pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/22907-2-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,295E-09 3,115E-06 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 1,994E-08 2,399E-05 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 4,781E-08 3,834E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 6,345E-08 3,817E-05 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 8,7E-07 4,187E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,297E-06 5,202E-04 ! regulation of centrosome cycle GO:0046605 7 5 1,000 7,155E-06 2,459E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 8,459E-06 2,544E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,073E-05 2,868E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,073E-05 2,581E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV GO:0009411 104 53 2,000 1,3E-05 2,844E-03 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 1,501E-05 3,009E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,892E-05 3,501E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2E-05 3,438E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,57E-05 4,123E-03 ! postreplication repair GO:0006301 22 9 1,000 2,57E-05 3,865E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 2,57E-05 3,638E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,638E-05 3,525E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,758E-05 3,492E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,211E-05 3,863E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 3,211E-05 3,679E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,211E-05 3,512E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,274E-05 3,425E-03 ! protein oligomerization GO:0051259 139 78 2,000 4,162E-05 4,173E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,705E-05 4,528E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 4,705E-05 4,354E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 5,557E-05 4,952E-03 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 5,557E-05 4,775E-03 ! regulation of DNA repair GO:0006282 21 13 1,000 5,557E-05 4,611E-03 ! positive regulation of protein modification process GO:0031401 136 88 2,000 5,97E-05 4,788E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 6,48E-05 5,029E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 6,48E-05 4,872E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 7,473E-05 5,448E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 7,5E-05 5,307E-03 ! interphase GO:0051325 213 98 2,000 8,227E-05 5,655E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 8,536E-05 5,705E-03 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 9,669E-05 6,287E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 9,669E-05 6,122E-03 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 1,087E-04 6,707E-03 ! centrosome cycle GO:0007098 25 18 1,000 1,087E-04 6,539E-03 ! skin development GO:0043588 36 19 1,000 1,214E-04 7,127E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,214E-04 6,957E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,349E-04 7,546E-03 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 1,349E-04 7,375E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 1,49E-04 7,966E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,638E-04 8,567E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,638E-04 8,385E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,955E-04 9,799E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,955E-04 9,599E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,124E-04 0,01021987 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,124E-04 0,01001948 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,3E-04 0,01064004 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,3E-04 0,01043929 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 2,3E-04 0,01024597 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,482E-04 0,01085869 ! fat cell differentiation GO:0045444 50 27 1,000 2,482E-04 0,01066478 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,672E-04 0,01127767 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,868E-04 0,01189789 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,868E-04 0,01169623 ! regulation of B cell activation GO:0050864 50 30 1,000 3,071E-04 0,01231627 ! spindle organization GO:0007051 46 32 1,000 3,498E-04 0,0137985 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,19E-04 0,01625975 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,19E-04 0,01600166 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 4,434E-04 0,01666935 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 4,434E-04 0,0164129 ! meiosis I GO:0007127 65 37 1,000 4,685E-04 0,01707882 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,943E-04 0,01774916 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,943E-04 0,01748814 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 5,756E-04 0,02007108 ! double-strand break repair GO:0006302 81 44 1,000 6,63E-04 0,02278808 ! epidermal cell differentiation GO:0009913 68 46 1,000 7,246E-04 0,02455477 ! response to calcium ion GO:0051592 81 47 1,000 7,564E-04 0,02527649 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,889E-04 0,02600036 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 7,889E-04 0,025649 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 8,558E-04 0,0274541 ! response to estrogen stimulus GO:0043627 93 51 1,000 8,903E-04 0,02818374 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 8,903E-04 0,02781772 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 9,254E-04 0,02854438 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 9,976E-04 0,03038251 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 1,355E-03 0,0407522 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 1,355E-03 0,04024909 ! regulation of cellular response to stress GO:0080135 128 67 1,000 1,531E-03 0,04491516 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,531E-03 0,04437401 ! chromosome segregation GO:0007059 113 67 1,000 1,531E-03 0,04384575 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 1,576E-03 0,04461929 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,576E-03 0,04410046 ! cell cycle checkpoint GO:0000075 137 69 1,000 1,623E-03 0,04487107 ! negative regulation of cell size GO:0045792 134 69 1,000 1,623E-03 0,04436118 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,623E-03 0,04386273 ! regulation of caspase activity GO:0043281 122 72 1,000 1,765E-03 0,04718301 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,765E-03 0,04666451 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,765E-03 0,04615729 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,765E-03 0,04566098 ! meiosis GO:0007126 121 74 1,000 1,863E-03 0,04768741 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 1,863E-03 0,04718544 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 1,913E-03 0,0479478 ! meiotic cell cycle GO:0051321 122 75 1,000 1,913E-03 0,04745349 ! positive regulation of ligase activity GO:0051351 124 77 1,000 2,015E-03 0,04947263 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,015E-03 0,04897291 ! negative regulation of organelle organization GO:0010639 161 78 1,000 2,067E-03 0,0497327 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 2,067E-03 0,0492403 ! regulation of peptidase activity GO:0052547 134 79 1,000 2,12E-03 0,04999749 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 2,12E-03 0,04951207 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,12E-03 0,049036 ! response to metal ion GO:0010038 140 80 1,000 2,173E-03 0,04978796 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,227E-03 0,05054005 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 2,392E-03 0,05378363 ! regulation of ligase activity GO:0051340 142 84 1,000 2,392E-03 0,05328563 ! response to unfolded protein GO:0006986 131 85 1,000 2,448E-03 0,05404035 ! positive regulation of cell activation GO:0050867 145 85 1,000 2,448E-03 0,05354908 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 2,505E-03 0,05430138 ! mitochondrion organization GO:0007005 148 86 1,000 2,505E-03 0,05381655 ! regulation of cell cycle process GO:0010564 149 90 1,000 2,739E-03 0,05832445 ! response to protein stimulus GO:0051789 149 91 1,000 2,799E-03 0,05908071 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,921E-03 0,06111949 GO:0010498|proteasomal protein catabolic process, ! regulation of DNA metabolic process GO:0051052 178 97 1,000 3,173E-03 0,06580701 ! cell cycle arrest GO:0007050 213 100 1,000 3,368E-03 0,06925433 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 4,309E-03 0,08786668 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,309E-03 0,0871283 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,309E-03 0,08640223 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,309E-03 0,08568816 ! neuron fate determination GO:0048664 7 5 0,000 4,309E-03 0,0849858 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,309E-03 0,08429486 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,309E-03 0,08361506 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,309E-03 0,08294614 ! polyol transport GO:0015791 12 5 0,000 4,309E-03 0,08228784 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,309E-03 0,0816399 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,309E-03 0,08100209 ! response to superoxide GO:0000303 10 5 0,000 4,309E-03 0,08037417 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,309E-03 0,07975591 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,309E-03 0,07914708 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,309E-03 0,07854748 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,309E-03 0,0779569 ! female meiosis GO:0007143 7 5 0,000 4,309E-03 0,07737513 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,309E-03 0,07680198 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,309E-03 0,07623726 ! cobalt ion transport GO:0006824 11 5 0,000 4,309E-03 0,07568079 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,309E-03 0,07513238 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,309E-03 0,07459185 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,309E-03 0,07405906 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,309E-03 0,07353381 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,309E-03 0,07301597 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,309E-03 0,07250537 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,309E-03 0,07200186 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,309E-03 0,0715053 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,309E-03 0,07101553 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,309E-03 0,07053243 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,309E-03 0,07005586 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,309E-03 0,06958569 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,309E-03 0,06912179 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,309E-03 0,06866403 ! negative chemotaxis GO:0050919 14 5 0,000 4,309E-03 0,06821229 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,309E-03 0,06776646 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,309E-03 0,06732641 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,309E-03 0,06689205 ! behavioral response to pain GO:0048266 9 5 0,000 4,309E-03 0,06646326 ! clathrin coat assembly GO:0048268 14 5 0,000 4,309E-03 0,06603992 ! Notch receptor processing GO:0007220 8 5 0,000 4,309E-03 0,06562195 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,309E-03 0,06520923 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,309E-03 0,06480167 ! micturition GO:0060073 9 5 0,000 4,309E-03 0,06439918 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,309E-03 0,06400165 ! copulation GO:0007620 9 5 0,000 4,309E-03 0,063609 ! glial cell fate commitment GO:0021781 13 5 0,000 4,309E-03 0,06322115 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,309E-03 0,06283799 ! spermidine metabolic process GO:0008216 7 5 0,000 4,309E-03 0,06245944 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,309E-03 0,06208544 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,309E-03 0,06171588 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,309E-03 0,0613507 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,309E-03 0,06098981 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,309E-03 0,06063315 ! grooming behavior GO:0007625 6 5 0,000 4,309E-03 0,06028063 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,309E-03 0,05993218 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,309E-03 0,05958775 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,309E-03 0,05924724 ! response to protozoan GO:0001562 10 5 0,000 4,309E-03 0,05891061 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,309E-03 0,05857778 ! lymph vessel development GO:0001945 10 5 0,000 4,309E-03 0,0582487 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,309E-03 0,05792328 ! endochondral ossification GO:0001958 16 5 0,000 4,309E-03 0,05760149 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,309E-03 0,05728325 ! parathyroid gland development GO:0060017 13 5 0,000 4,309E-03 0,0569685 ! anagen GO:0042640 6 5 0,000 4,309E-03 0,0566572 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,309E-03 0,05634928 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,309E-03 0,05604469 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,309E-03 0,05574338 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,309E-03 0,05544528 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,309E-03 0,05515036 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,309E-03 0,05485856 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,309E-03 0,05456983 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,309E-03 0,05428412 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,309E-03 0,05400139 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,309E-03 0,05372159 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,309E-03 0,05344468 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,309E-03 0,0531706 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,309E-03 0,05289933 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,309E-03 0,0526308 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,309E-03 0,05236499 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,309E-03 0,05210185 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,309E-03 0,05184134 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,309E-03 0,05158342 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,309E-03 0,05132806 ! histidine catabolic process GO:0006548 6 5 0,000 4,309E-03 0,05107521 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,309E-03 0,05082484 ! microvillus organization GO:0032528 7 5 0,000 4,309E-03 0,05057692 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,309E-03 0,0503314 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,309E-03 0,05008825 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,309E-03 0,04984744 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,309E-03 0,04960894 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,309E-03 0,0493727 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,309E-03 0,04913871 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,309E-03 0,04890692 ! polyol catabolic process GO:0046174 7 5 0,000 4,309E-03 0,04867731 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,309E-03 0,04844985 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,309E-03 0,0482245 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,309E-03 0,04800124 ! muscle cell migration GO:0014812 8 5 0,000 4,309E-03 0,04778004 ! mitochondrial fission GO:0000266 8 5 0,000 4,309E-03 0,04756086 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,309E-03 0,04734369 ! mRNA transcription GO:0009299 9 5 0,000 4,309E-03 0,04712849 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,309E-03 0,04691524 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,309E-03 0,04670391 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,309E-03 0,04649447 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,309E-03 0,04628691 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,309E-03 0,04608119 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,309E-03 0,04587729 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,309E-03 0,04567519 ! response to food GO:0032094 6 5 0,000 4,309E-03 0,04547486 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,309E-03 0,04527628 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,309E-03 0,04507943 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,309E-03 0,04488428 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,309E-03 0,04469081 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,309E-03 0,044499 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,309E-03 0,04430884 ! forebrain neuron development GO:0021884 13 5 0,000 4,309E-03 0,04412029 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,309E-03 0,04393334 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,309E-03 0,04374797 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,309E-03 0,04356415 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,309E-03 0,04338187 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,309E-03 0,04320112 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,309E-03 0,04302186 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,309E-03 0,04284408 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,309E-03 0,04266777 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,309E-03 0,0424929 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,309E-03 0,04231946 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,309E-03 0,04214743 ! basic amino acid transport GO:0015802 11 5 0,000 4,309E-03 0,04197679 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,309E-03 0,04180753 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,309E-03 0,04163963 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,309E-03 0,04147307 ! depyrimidination GO:0045008 10 5 0,000 4,309E-03 0,04130784 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,309E-03 0,04114392 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,309E-03 0,0409813 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,309E-03 0,04081995 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,309E-03 0,04065987 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,309E-03 0,04050105 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,309E-03 0,04034345 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,309E-03 0,04018708 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,309E-03 0,04003192 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,309E-03 0,03987795 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,309E-03 0,03972516 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,309E-03 0,03957354 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,309E-03 0,03942307 ! response to arsenic GO:0046685 10 5 0,000 4,309E-03 0,03927374 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,309E-03 0,03912554 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,309E-03 0,03897845 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,309E-03 0,03883246 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,309E-03 0,03868757 ! response to cadmium ion GO:0046686 7 5 0,000 4,309E-03 0,03854375 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,309E-03 0,03840099 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,309E-03 0,03825929 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,309E-03 0,03811863 ! decidualization GO:0046697 11 5 0,000 4,309E-03 0,037979 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,309E-03 0,03784039 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,309E-03 0,03770279 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,309E-03 0,03756619 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,309E-03 0,03743057 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,309E-03 0,03729593 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,309E-03 0,03716225 ! neural tube patterning GO:0021532 7 5 0,000 4,309E-03 0,03702953 ! embryonic cleavage GO:0040016 6 5 0,000 4,309E-03 0,03689775 ! peroxisome fission GO:0016559 5 5 0,000 4,309E-03 0,03676691 ! histone demethylation GO:0016577 10 5 0,000 4,309E-03 0,03663699 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,309E-03 0,03650799 ! mitotic recombination GO:0006312 9 5 0,000 4,309E-03 0,03637989 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,309E-03 0,03625268 ! metaphase plate congression GO:0051310 7 5 0,000 4,309E-03 0,03612637 ! regulation of sterol transport GO:0032371 7 5 0,000 4,309E-03 0,03600093 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,309E-03 0,03587636 ! enteric nervous system development GO:0048484 8 5 0,000 4,309E-03 0,03575265 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,309E-03 0,03562979 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,309E-03 0,03550777 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,309E-03 0,03538658 ! muscle cell proliferation GO:0033002 11 5 0,000 4,309E-03 0,03526622 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,309E-03 0,03514667 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,309E-03 0,03502793 ! plasminogen activation GO:0031639 5 5 0,000 4,309E-03 0,03490999 ! B cell homeostasis GO:0001782 13 5 0,000 4,309E-03 0,03479284 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,309E-03 0,03467648 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,309E-03 0,03456089 ! metaphase GO:0051323 8 5 0,000 4,309E-03 0,03444607 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,309E-03 0,03433201 ! cellular response to nutrient GO:0031670 8 5 0,000 4,309E-03 0,03421871 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,309E-03 0,03410614 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,309E-03 0,03399432 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,309E-03 0,03388323 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,309E-03 0,03377286 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,309E-03 0,03366321 ! response to redox state GO:0051775 5 5 0,000 4,309E-03 0,03355426 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,309E-03 0,03344603 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,309E-03 0,03333848 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,309E-03 0,03323163 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,309E-03 0,03312546 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,309E-03 0,03301996 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,309E-03 0,03291514 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,309E-03 0,03281097 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,309E-03 0,03270747 ! striatum development GO:0021756 9 5 0,000 4,309E-03 0,03260462 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,309E-03 0,03250241 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 4,309E-03 0,03240084 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,309E-03 0,0322999 ! glial cell migration GO:0008347 11 5 0,000 4,309E-03 0,03219959 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,309E-03 0,0320999 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,309E-03 0,03200083 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,309E-03 0,03190236 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,309E-03 0,0318045 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,309E-03 0,03170724 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,309E-03 0,03161057 ! neuroprotection GO:0043526 6 5 0,000 4,309E-03 0,03151449 ! neural plate development GO:0001840 8 5 0,000 4,309E-03 0,03141899 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,309E-03 0,03132407 ! regulation of sensory perception GO:0051931 7 5 0,000 4,309E-03 0,03122972 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,309E-03 0,03113594 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,309E-03 0,03104272 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,309E-03 0,03095005 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,309E-03 0,03085794 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,309E-03 0,03076637 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,309E-03 0,03067535 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,309E-03 0,03058486 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,309E-03 0,03049491 ! spindle assembly GO:0051225 6 5 0,000 4,309E-03 0,03040548 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,309E-03 0,03031657 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,309E-03 0,03022819 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,309E-03 0,03014031 ! drug metabolic process GO:0017144 6 5 0,000 4,309E-03 0,03005295 ! stem cell division GO:0017145 11 5 0,000 4,309E-03 0,02996609 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,309E-03 0,02987973 ! organ regeneration GO:0031100 7 5 0,000 4,309E-03 0,02979387 ! carnitine metabolic process GO:0009437 7 5 0,000 4,309E-03 0,0297085 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,309E-03 0,02962362 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,309E-03 0,02953922 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,169E-03 0,0353317 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,169E-03 0,03523161 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,169E-03 0,03513209 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,169E-03 0,03503313 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,169E-03 0,03493472 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,169E-03 0,03483686 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,169E-03 0,03473955 ! sleep GO:0030431 13 6 0,000 5,169E-03 0,03464278 ! response to oxygen radical GO:0000305 11 6 0,000 5,169E-03 0,03454655 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,169E-03 0,03445086 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,169E-03 0,03435569 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,169E-03 0,03426105 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,169E-03 0,03416692 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,169E-03 0,03407331 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,169E-03 0,03398022 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,169E-03 0,03388763 ! forebrain regionalization GO:0021871 8 6 0,000 5,169E-03 0,03379554 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,169E-03 0,03370396 ! male meiosis GO:0007140 7 6 0,000 5,169E-03 0,03361286 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,169E-03 0,03352226 ! response to zinc ion GO:0010043 9 6 0,000 5,169E-03 0,03343215 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,169E-03 0,03334252 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,169E-03 0,03325337 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,169E-03 0,03316469 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,169E-03 0,03307649 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,169E-03 0,03298875 ! malate metabolic process GO:0006108 11 6 0,000 5,169E-03 0,03290148 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,169E-03 0,03281467 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,169E-03 0,03272831 ! protein refolding GO:0042026 15 6 0,000 5,169E-03 0,03264241 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,169E-03 0,03255696 ! opsonization GO:0008228 8 6 0,000 5,169E-03 0,03247196 ! mating behavior GO:0007617 7 6 0,000 5,169E-03 0,03238739 ! neuron remodeling GO:0016322 15 6 0,000 5,169E-03 0,03230327 ! erythrocyte maturation GO:0043249 7 6 0,000 5,169E-03 0,03221958 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,169E-03 0,03213633 ! equilibrioception GO:0050957 14 6 0,000 5,169E-03 0,0320535 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,169E-03 0,0319711 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,169E-03 0,03188913 ! photoreceptor cell development GO:0042461 10 6 0,000 5,169E-03 0,03180757 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,169E-03 0,03172643 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,169E-03 0,0316457 ! response to interferon-gamma GO:0034341 15 6 0,000 5,169E-03 0,03156538 ! toxin metabolic process GO:0009404 11 6 0,000 5,169E-03 0,03148547 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,169E-03 0,03140596 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,169E-03 0,03132685 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,169E-03 0,03124814 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,169E-03 0,03116982 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,169E-03 0,0310919 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,169E-03 0,03101436 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,169E-03 0,03093721 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,169E-03 0,03086045 ! thymic T cell selection GO:0045061 12 6 0,000 5,169E-03 0,03078406 ! protein lipoylation GO:0009249 10 6 0,000 5,169E-03 0,03070805 ! cysteine metabolic process GO:0006534 10 6 0,000 5,169E-03 0,03063241 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,169E-03 0,03055715 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,169E-03 0,03048225 ! glutamate catabolic process GO:0006538 10 6 0,000 5,169E-03 0,03040773 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,169E-03 0,03033356 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,169E-03 0,03025976 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,169E-03 0,03018631 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,169E-03 0,03011322 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,169E-03 0,03004048 ! hyperosmotic response GO:0006972 9 6 0,000 5,169E-03 0,0299681 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,169E-03 0,02989606 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,169E-03 0,02982436 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,169E-03 0,02975301 ! urea metabolic process GO:0019627 7 6 0,000 5,169E-03 0,029682 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,169E-03 0,02961133 ! neutrophil activation GO:0042119 8 6 0,000 5,169E-03 0,029541 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,169E-03 0,02947099 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,169E-03 0,02940132 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,169E-03 0,02933198 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,169E-03 0,02926296 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,169E-03 0,02919427 ! neuron apoptosis GO:0051402 9 6 0,000 5,169E-03 0,0291259 ! nucleoside salvage GO:0043174 9 6 0,000 5,169E-03 0,02905785 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,169E-03 0,02899012 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,169E-03 0,0289227 ! T cell mediated immunity GO:0002456 16 6 0,000 5,169E-03 0,02885559 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,169E-03 0,0287888 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,169E-03 0,02872231 ! carnitine transport GO:0015879 10 6 0,000 5,169E-03 0,02865613 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,169E-03 0,02859025 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,169E-03 0,02852468 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,169E-03 0,0284594 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,169E-03 0,02839443 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,169E-03 0,02832975 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,169E-03 0,02826536 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,169E-03 0,02820127 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,169E-03 0,02813747 ! establishment of spindle localization GO:0051293 12 6 0,000 5,169E-03 0,02807395 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,169E-03 0,02801072 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,169E-03 0,02794777 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,169E-03 0,02788511 ! neural nucleus development GO:0048857 14 6 0,000 5,169E-03 0,02782273 ! response to UV-C GO:0010225 11 6 0,000 5,169E-03 0,02776062 ! astrocyte development GO:0014002 15 6 0,000 5,169E-03 0,0276988 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,169E-03 0,02763724 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,169E-03 0,02757596 ! interaction with symbiont GO:0051702 13 6 0,000 5,169E-03 0,02751495 ! regulation of dendrite development GO:0050773 16 6 0,000 5,169E-03 0,02745422 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,169E-03 0,02739374 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,169E-03 0,02733354 ! response to copper ion GO:0046688 10 6 0,000 5,169E-03 0,0272736 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,169E-03 0,02721392 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,169E-03 0,0271545 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,169E-03 0,02709534 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,169E-03 0,02703643 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,169E-03 0,02697779 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,169E-03 0,02691939 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,169E-03 0,02686125 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,169E-03 0,02680336 ! hair follicle maturation GO:0048820 7 6 0,000 5,169E-03 0,02674572 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,169E-03 0,02668833 ! Schwann cell development GO:0014044 15 6 0,000 5,169E-03 0,02663118 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,169E-03 0,02657427 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,169E-03 0,02651761 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,169E-03 0,02646119 ! subpallium development GO:0021544 10 6 0,000 5,169E-03 0,02640501 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,169E-03 0,02634907 ! histone ubiquitination GO:0016574 8 6 0,000 5,169E-03 0,02629336 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,169E-03 0,02623789 ! maintenance of organ identity GO:0048496 9 6 0,000 5,169E-03 0,02618265 ! G2 phase GO:0051319 16 6 0,000 5,169E-03 0,02612765 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,169E-03 0,02607287 ! establishment of planar polarity GO:0001736 7 6 0,000 5,169E-03 0,02601833 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,169E-03 0,02596401 ! membrane to membrane docking GO:0022614 14 6 0,000 5,169E-03 0,02590992 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,169E-03 0,02585605 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,169E-03 0,02580241 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,169E-03 0,02574898 ! receptor internalization GO:0031623 10 6 0,000 5,169E-03 0,02569578 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,169E-03 0,0256428 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,169E-03 0,02559004 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,169E-03 0,02553749 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,169E-03 0,02548516 ! protein deubiquitination GO:0016579 14 6 0,000 5,169E-03 0,02543305 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,169E-03 0,02538114 ! protein destabilization GO:0031648 9 6 0,000 5,169E-03 0,02532945 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,169E-03 0,02527797 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,169E-03 0,02522669 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,169E-03 0,02517563 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,169E-03 0,02512477 ! progesterone metabolic process GO:0042448 10 6 0,000 5,169E-03 0,02507411 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,169E-03 0,02502366 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,169E-03 0,02497341 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,169E-03 0,02492337 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,169E-03 0,02487352 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,169E-03 0,02482387 ! determination of adult lifespan GO:0008340 15 6 0,000 5,169E-03 0,02477442 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,169E-03 0,02472517 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,169E-03 0,02467611 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,169E-03 0,02462725 ! catecholamine transport GO:0051937 9 6 0,000 5,169E-03 0,02457858 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,169E-03 0,0245301 ! sensory cilium assembly GO:0035058 10 6 0,000 5,169E-03 0,02448181 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,169E-03 0,02443371 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,169E-03 0,0243858 ! maternal placenta development GO:0001893 12 6 0,000 5,169E-03 0,02433808 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,169E-03 0,02429055 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,169E-03 0,0242432 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,169E-03 0,02419603 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,169E-03 0,02414905 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,169E-03 0,02410225 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,169E-03 0,02405563 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,169E-03 0,02400919 ! tRNA transcription GO:0009304 14 7 0,000 6,028E-03 0,02794515 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,028E-03 0,02789141 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 6,028E-03 0,02783788 ! regulation of helicase activity GO:0051095 15 7 0,000 6,028E-03 0,02778455 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,028E-03 0,02773142 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,028E-03 0,0276785 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,028E-03 0,02762578 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,028E-03 0,02757326 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,028E-03 0,02752094 ! prostate gland development GO:0030850 13 7 0,000 6,028E-03 0,02746881 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,028E-03 0,02741689 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,028E-03 0,02736516 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,028E-03 0,02731362 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,028E-03 0,02726228 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,028E-03 0,02721113 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,028E-03 0,02716018 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,028E-03 0,02710941 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,028E-03 0,02705883 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,028E-03 0,02700844 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,028E-03 0,02695824 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,028E-03 0,02690823 ! glycolipid transport GO:0046836 10 7 0,000 6,028E-03 0,0268584 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,028E-03 0,02680875 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,028E-03 0,02675929 ! neuron adhesion GO:0007158 12 7 0,000 6,028E-03 0,02671001 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,028E-03 0,02666091 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,028E-03 0,02661199 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,028E-03 0,02656325 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,028E-03 0,02651469 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,028E-03 0,0264663 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,028E-03 0,02641809 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,028E-03 0,02637006 ! mRNA stabilization GO:0048255 18 7 0,000 6,028E-03 0,0263222 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,028E-03 0,02627452 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,028E-03 0,02622701 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,028E-03 0,02617966 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,028E-03 0,02613249 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,028E-03 0,02608549 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,028E-03 0,02603866 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,028E-03 0,025992 ! lipoprotein transport GO:0042953 14 7 0,000 6,028E-03 0,0259455 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,028E-03 0,02589917 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,028E-03 0,025853 ! rhythmic behavior GO:0007622 15 7 0,000 6,028E-03 0,025807 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,028E-03 0,02576116 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,028E-03 0,02571549 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,028E-03 0,02566997 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,028E-03 0,02562462 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,028E-03 0,02557943 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,028E-03 0,02553439 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,028E-03 0,02548951 ! mechanosensory behavior GO:0007638 14 7 0,000 6,028E-03 0,0254448 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,028E-03 0,02540023 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,028E-03 0,02535583 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,028E-03 0,02531158 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,028E-03 0,02526748 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,028E-03 0,02522354 ! spinal cord patterning GO:0021511 13 7 0,000 6,028E-03 0,02517975 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,028E-03 0,02513611 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,028E-03 0,02509262 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,028E-03 0,02504928 ! adrenal gland development GO:0030325 17 7 0,000 6,028E-03 0,02500609 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,028E-03 0,02496305 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,028E-03 0,02492016 ! ovulation GO:0030728 9 7 0,000 6,028E-03 0,02487742 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,028E-03 0,02483482 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,028E-03 0,02479237 ! microtubule nucleation GO:0007020 20 7 0,000 6,028E-03 0,02475006 ! proline biosynthetic process GO:0006561 10 7 0,000 6,028E-03 0,02470789 ! thyroid hormone generation GO:0006590 13 7 0,000 6,028E-03 0,02466587 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,028E-03 0,024624 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,028E-03 0,02458226 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,028E-03 0,02454067 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,028E-03 0,02449921 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,028E-03 0,0244579 ! galactose metabolic process GO:0006012 13 7 0,000 6,028E-03 0,02441672 ! vesicle fusion GO:0006906 17 7 0,000 6,028E-03 0,02437569 ! response to dietary excess GO:0002021 8 7 0,000 6,028E-03 0,02433479 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,028E-03 0,02429403 ! intracellular pH reduction GO:0051452 11 7 0,000 6,028E-03 0,0242534 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,028E-03 0,02421291 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,028E-03 0,02417256 ! organ growth GO:0035265 15 7 0,000 6,028E-03 0,02413234 ! purine salvage GO:0043101 10 7 0,000 6,028E-03 0,02409225 ! nucleoside transport GO:0015858 8 7 0,000 6,028E-03 0,0240523 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,028E-03 0,02401247 ! parturition GO:0007567 14 7 0,000 6,028E-03 0,02397278 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,028E-03 0,02393322 ! rRNA modification GO:0000154 14 7 0,000 6,028E-03 0,0238938 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,028E-03 0,0238545 ! spindle checkpoint GO:0031577 15 7 0,000 6,028E-03 0,02381533 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,028E-03 0,02377629 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,028E-03 0,02373737 ! macrophage differentiation GO:0030225 11 7 0,000 6,028E-03 0,02369858 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,028E-03 0,02365992 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,028E-03 0,02362139 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,028E-03 0,02358298 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,028E-03 0,0235447 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,028E-03 0,02350654 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,028E-03 0,0234685 ! fibrinolysis GO:0042730 10 7 0,000 6,028E-03 0,02343059 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,028E-03 0,0233928 ! eating behavior GO:0042755 7 7 0,000 6,028E-03 0,02335513 ! B cell lineage commitment GO:0002326 21 7 0,000 6,028E-03 0,02331758 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,028E-03 0,02328015 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,028E-03 0,02324284 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,028E-03 0,02320565 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,028E-03 0,02316858 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,028E-03 0,02313163 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,028E-03 0,0230948 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,028E-03 0,02305808 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,028E-03 0,02302148 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,028E-03 0,022985 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,028E-03 0,02294863 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,028E-03 0,02291238 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,028E-03 0,02287624 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,028E-03 0,02284021 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,028E-03 0,0228043 ! regulation of meiosis GO:0040020 12 7 0,000 6,028E-03 0,0227685 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,028E-03 0,02273281 ! T cell lineage commitment GO:0002360 16 7 0,000 6,028E-03 0,02269724 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,028E-03 0,02266177 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,028E-03 0,02262642 ! oxygen homeostasis GO:0032364 12 7 0,000 6,028E-03 0,02259117 ! transcription termination GO:0006353 13 7 0,000 6,028E-03 0,02255604 ! response to tumor cell GO:0002347 13 7 0,000 6,028E-03 0,02252102 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,028E-03 0,0224861 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,028E-03 0,02245129 ! anaphase GO:0051322 17 7 0,000 6,028E-03 0,02241659 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,028E-03 0,022382 ! axonal fasciculation GO:0007413 18 7 0,000 6,028E-03 0,02234751 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,028E-03 0,02231313 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,028E-03 0,02227885 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,028E-03 0,02224468 ! diuresis GO:0030146 12 7 0,000 6,028E-03 0,02221062 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,028E-03 0,02217666 ! thiamin metabolic process GO:0006772 7 7 0,000 6,028E-03 0,0221428 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,028E-03 0,02210905 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,028E-03 0,02207539 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,028E-03 0,02204185 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,028E-03 0,0220084 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,028E-03 0,02197505 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,028E-03 0,02194181 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,028E-03 0,02190866 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,028E-03 0,02187562 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,028E-03 0,02184267 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,028E-03 0,02180983 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,028E-03 0,02177708 ! lymph node development GO:0048535 10 7 0,000 6,028E-03 0,02174443 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,028E-03 0,02171188 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,028E-03 0,02167942 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,028E-03 0,02164707 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,028E-03 0,0216148 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,028E-03 0,02158264 ! adult feeding behavior GO:0008343 9 7 0,000 6,028E-03 0,02155057 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,028E-03 0,0215186 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,028E-03 0,02148672 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,028E-03 0,02145493 ! muscle adaptation GO:0043500 14 7 0,000 6,028E-03 0,02142324 ! embryonic heart tube development GO:0035050 10 7 0,000 6,028E-03 0,02139164 ! retina homeostasis GO:0001895 12 7 0,000 6,028E-03 0,02136014 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,028E-03 0,02132873 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,028E-03 0,02129741 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,028E-03 0,02126618 ! protein prenylation GO:0018342 18 7 0,000 6,028E-03 0,02123504 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,028E-03 0,021204 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,028E-03 0,02117304 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,028E-03 0,02114218 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,886E-03 0,02411731 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,886E-03 0,02408226 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,886E-03 0,0240473 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,886E-03 0,02401245 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,886E-03 0,0239777 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,886E-03 0,02394305 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,886E-03 0,0239085 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,886E-03 0,02387405 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,886E-03 0,0238397 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,886E-03 0,02380545 ! meiotic prophase I GO:0007128 13 8 0,000 6,886E-03 0,02377129 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,886E-03 0,02373724 ! oligopeptide transport GO:0006857 15 8 0,000 6,886E-03 0,02370328 ! UTP metabolic process GO:0046051 8 8 0,000 6,886E-03 0,02366942 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,886E-03 0,02363565 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,886E-03 0,02360198 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,886E-03 0,02356841 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,886E-03 0,02353493 ! succinate metabolic process GO:0006105 14 8 0,000 6,886E-03 0,02350155 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,886E-03 0,02346826 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,886E-03 0,02343507 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,886E-03 0,02340197 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,886E-03 0,02336896 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,886E-03 0,02333605 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,886E-03 0,02330322 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,886E-03 0,02327049 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,886E-03 0,02323786 ! reflex GO:0060004 16 8 0,000 6,886E-03 0,02320531 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,886E-03 0,02317286 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,886E-03 0,02314049 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,886E-03 0,02310822 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,886E-03 0,02307603 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,886E-03 0,02304394 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,886E-03 0,02301193 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,886E-03 0,02298002 ! pigment granule organization GO:0048753 16 8 0,000 6,886E-03 0,02294819 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,886E-03 0,02291645 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,886E-03 0,0228848 ! astrocyte differentiation GO:0048708 18 8 0,000 6,886E-03 0,02285323 ! histidine metabolic process GO:0006547 16 8 0,000 6,886E-03 0,02282175 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,886E-03 0,02279036 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,886E-03 0,02275906 ! glycine catabolic process GO:0006546 13 8 0,000 6,886E-03 0,02272784 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,886E-03 0,0226967 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,886E-03 0,02266565 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,886E-03 0,02263469 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,886E-03 0,02260381 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,886E-03 0,02257301 ! melanin metabolic process GO:0006582 15 8 0,000 6,886E-03 0,0225423 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,886E-03 0,02251167 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,886E-03 0,02248113 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,886E-03 0,02245067 ! macrophage activation GO:0042116 12 8 0,000 6,886E-03 0,02242029 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,886E-03 0,02238999 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,886E-03 0,02235977 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,886E-03 0,02232964 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,886E-03 0,02229959 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,886E-03 0,02226961 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,886E-03 0,02223972 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,886E-03 0,02220991 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,886E-03 0,02218018 ! osteoblast development GO:0002076 16 8 0,000 6,886E-03 0,02215052 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,886E-03 0,02212095 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,886E-03 0,02209146 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,886E-03 0,02206204 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,886E-03 0,0220327 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,886E-03 0,02200344 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,886E-03 0,02197426 ! response to UV-B GO:0010224 16 8 0,000 6,886E-03 0,02194516 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,886E-03 0,02191613 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,886E-03 0,02188718 ! intermediate filament organization GO:0045109 12 8 0,000 6,886E-03 0,0218583 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,886E-03 0,0218295 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,886E-03 0,02180078 ! cellular extravasation GO:0045123 12 8 0,000 6,886E-03 0,02177213 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,886E-03 0,02174356 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,886E-03 0,02171506 ! response to antibiotic GO:0046677 11 8 0,000 6,886E-03 0,02168664 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,886E-03 0,02165829 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,886E-03 0,02163002 ! DNA topological change GO:0006265 12 8 0,000 6,886E-03 0,02160182 ! response to tropane GO:0014073 15 8 0,000 6,886E-03 0,02157369 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,886E-03 0,02154563 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,886E-03 0,02151765 ! melanosome transport GO:0032402 13 8 0,000 6,886E-03 0,02148974 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,886E-03 0,02146191 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,886E-03 0,02143414 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,886E-03 0,02140645 ! mast cell activation GO:0045576 14 8 0,000 6,886E-03 0,02137883 ! multicellular organismal aging GO:0010259 18 8 0,000 6,886E-03 0,02135128 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 6,886E-03 0,0213238 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,886E-03 0,02129639 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,886E-03 0,02126905 ! nucleosome disassembly GO:0006337 14 8 0,000 6,886E-03 0,02124179 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,886E-03 0,02121459 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,886E-03 0,02118746 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,886E-03 0,0211604 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,886E-03 0,02113341 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,886E-03 0,02110649 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,886E-03 0,02107963 ! intracellular lipid transport GO:0032365 13 8 0,000 6,886E-03 0,02105285 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,886E-03 0,02102613 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,886E-03 0,02099948 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,886E-03 0,0209729 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,886E-03 0,02094639 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,886E-03 0,02091994 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,886E-03 0,02089356 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,886E-03 0,02086724 ! hormone catabolic process GO:0042447 17 8 0,000 6,886E-03 0,020841 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,886E-03 0,02081481 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,886E-03 0,0207887 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,886E-03 0,02076265 ! ATP catabolic process GO:0006200 11 8 0,000 6,886E-03 0,02073666 ! blastocyst growth GO:0001832 19 8 0,000 6,886E-03 0,02071074 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,886E-03 0,02068488 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,886E-03 0,02065909 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,886E-03 0,02063337 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,886E-03 0,0206077 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,886E-03 0,0205821 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,886E-03 0,02055657 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,886E-03 0,02053109 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,886E-03 0,02050568 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,886E-03 0,02048034 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,886E-03 0,02045505 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,886E-03 0,02042983 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,886E-03 0,02040467 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,886E-03 0,02037957 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,886E-03 0,02035454 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,886E-03 0,02032956 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,886E-03 0,02030465 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,886E-03 0,02027979 ! regulation of developmental growth GO:0048638 15 9 0,000 7,744E-03 0,02277743 ! axon extension GO:0048675 15 9 0,000 7,744E-03 0,02274962 ! autophagic vacuole formation GO:0000045 15 9 0,000 7,744E-03 0,02272187 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,744E-03 0,0226942 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 7,744E-03 0,02266659 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 7,744E-03 0,02263905 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,744E-03 0,02261157 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 7,744E-03 0,02258417 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 7,744E-03 0,02255682 ! cell proliferation in forebrain GO:0021846 15 9 0,000 7,744E-03 0,02252955 ! phosphate transport GO:0006817 19 9 0,000 7,744E-03 0,02250234 ! reproductive behavior GO:0019098 19 9 0,000 7,744E-03 0,02247519 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,744E-03 0,02244812 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 7,744E-03 0,0224211 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,744E-03 0,02239415 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 7,744E-03 0,02236727 ! GTP metabolic process GO:0046039 9 9 0,000 7,744E-03 0,02234045 ! RNA methylation GO:0001510 15 9 0,000 7,744E-03 0,0223137 ! elastic fiber assembly GO:0048251 15 9 0,000 7,744E-03 0,022287 ! induction of positive chemotaxis GO:0050930 15 9 0,000 7,744E-03 0,02226038 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 7,744E-03 0,02223381 ! artery development GO:0060840 24 9 0,000 7,744E-03 0,02220731 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 7,744E-03 0,02218088 ! regulation of glycolysis GO:0006110 21 9 0,000 7,744E-03 0,0221545 ! cerebral cortex cell migration GO:0021795 15 9 0,000 7,744E-03 0,02212819 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 7,744E-03 0,02210194 ! chemosensory behavior GO:0007635 20 9 0,000 7,744E-03 0,02207575 ! microtubule bundle formation GO:0001578 21 9 0,000 7,744E-03 0,02204963 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,744E-03 0,02202357 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 7,744E-03 0,02199756 ! leukocyte degranulation GO:0043299 16 9 0,000 7,744E-03 0,02197162 ! bile acid and bile salt transport GO:0015721 13 9 0,000 7,744E-03 0,02194574 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 7,744E-03 0,02191992 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 7,744E-03 0,02189417 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,744E-03 0,02186847 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,744E-03 0,02184283 ! protein targeting to ER GO:0045047 22 9 0,000 7,744E-03 0,02181726 ! ceramide biosynthetic process GO:0046513 19 9 0,000 7,744E-03 0,02179174 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 7,744E-03 0,02176628 ! T cell selection GO:0045058 23 9 0,000 7,744E-03 0,02174088 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 7,744E-03 0,02171554 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 7,744E-03 0,02169026 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,744E-03 0,02166504 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 7,744E-03 0,02163988 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 7,744E-03 0,02161478 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,744E-03 0,02158973 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,744E-03 0,02156474 ! mannose metabolic process GO:0006013 13 9 0,000 7,744E-03 0,02153981 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 7,744E-03 0,02151494 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 7,744E-03 0,02149012 ! Rac protein signal transduction GO:0016601 17 9 0,000 7,744E-03 0,02146536 ! receptor clustering GO:0043113 18 9 0,000 7,744E-03 0,02144066 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 7,744E-03 0,02141602 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,744E-03 0,02139143 ! ruffle organization GO:0031529 15 9 0,000 7,744E-03 0,0213669 ! retinol metabolic process GO:0042572 18 9 0,000 7,744E-03 0,02134242 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 7,744E-03 0,021318 ! behavioral fear response GO:0001662 22 9 0,000 7,744E-03 0,02129364 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 7,744E-03 0,02126933 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 7,744E-03 0,02124508 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 7,744E-03 0,02122088 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 7,744E-03 0,02119674 ! protein heterooligomerization GO:0051291 16 9 0,000 7,744E-03 0,02117265 ! oligodendrocyte development GO:0014003 10 9 0,000 7,744E-03 0,02114862 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 7,744E-03 0,02112464 ! segment specification GO:0007379 13 9 0,000 7,744E-03 0,02110072 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,744E-03 0,02107685 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 7,744E-03 0,02105304 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,744E-03 0,02102927 ! response to amine stimulus GO:0014075 13 9 0,000 7,744E-03 0,02100556 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,744E-03 0,02098191 ! erythrocyte development GO:0048821 15 9 0,000 7,744E-03 0,02095831 ! gas homeostasis GO:0033483 16 9 0,000 7,744E-03 0,02093476 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,744E-03 0,02091126 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 7,744E-03 0,02088782 ! renal water homeostasis GO:0003091 14 9 0,000 7,744E-03 0,02086443 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 7,744E-03 0,02084109 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 7,744E-03 0,02081781 ! icosanoid secretion GO:0032309 15 9 0,000 7,744E-03 0,02079457 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 7,744E-03 0,02077139 ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,744E-03 0,02074826 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 7,744E-03 0,02072518 ! regulation of cell division GO:0051302 15 9 0,000 7,744E-03 0,02070215 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 7,744E-03 0,02067917 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,744E-03 0,02065625 ! sterol catabolic process GO:0016127 11 9 0,000 7,744E-03 0,02063337 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,744E-03 0,02061055 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 7,744E-03 0,02058777 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 7,744E-03 0,02056505 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 7,744E-03 0,02054238 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 7,744E-03 0,02051975 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 7,744E-03 0,02049718 ! musculoskeletal movement GO:0050881 14 9 0,000 7,744E-03 0,02047466 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 7,744E-03 0,02045218 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 7,744E-03 0,02042975 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,744E-03 0,02040738 ! purine base metabolic process GO:0006144 21 9 0,000 7,744E-03 0,02038505 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 7,744E-03 0,02036277 ! pigment granule transport GO:0051904 17 9 0,000 7,744E-03 0,02034054 ! regulation of fibrinolysis GO:0051917 16 9 0,000 7,744E-03 0,02031836 ! regulation of telomere maintenance GO:0032204 14 9 0,000 7,744E-03 0,02029623 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 7,744E-03 0,02027414 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,744E-03 0,0202521 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,744E-03 0,02023012 ! mitochondrion localization GO:0051646 15 9 0,000 7,744E-03 0,02020817 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,601E-03 0,0224199 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,601E-03 0,02239563 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,601E-03 0,02237142 ! synapsis GO:0007129 13 10 0,000 8,601E-03 0,02234726 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,601E-03 0,02232316 ! N-glycan processing GO:0006491 20 10 0,000 8,601E-03 0,0222991 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 8,601E-03 0,0222751 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,601E-03 0,02225115 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,601E-03 0,02222725 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,601E-03 0,0222034 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,601E-03 0,0221796 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,601E-03 0,02215585 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,601E-03 0,02213216 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,601E-03 0,02210851 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,601E-03 0,02208492 ! androgen metabolic process GO:0008209 17 10 0,000 8,601E-03 0,02206137 ! phospholipid efflux GO:0033700 16 10 0,000 8,601E-03 0,02203788 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,601E-03 0,02201443 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,601E-03 0,02199104 ! lung alveolus development GO:0048286 26 10 0,000 8,601E-03 0,02196769 ! pathogenesis GO:0009405 13 10 0,000 8,601E-03 0,0219444 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,601E-03 0,02192115 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,601E-03 0,02189795 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,601E-03 0,02187481 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,601E-03 0,02185171 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,601E-03 0,02182866 ! endoderm development GO:0007492 16 10 0,000 8,601E-03 0,02180566 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,601E-03 0,0217827 ! arginine catabolic process GO:0006527 13 10 0,000 8,601E-03 0,0217598 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,601E-03 0,02173694 ! proline metabolic process GO:0006560 13 10 0,000 8,601E-03 0,02171413 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,601E-03 0,02169137 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,601E-03 0,02166866 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,601E-03 0,02164599 ! V(D)J recombination GO:0033151 28 10 0,000 8,601E-03 0,02162337 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,601E-03 0,0216008 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,601E-03 0,02157828 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 8,601E-03 0,0215558 ! B cell proliferation GO:0042100 18 10 0,000 8,601E-03 0,02153337 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,601E-03 0,02151098 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,601E-03 0,02148865 ! multicellular organism growth GO:0035264 18 10 0,000 8,601E-03 0,02146636 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,601E-03 0,02144411 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,601E-03 0,02142191 ! epithelial cell development GO:0002064 20 10 0,000 8,601E-03 0,02139976 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,601E-03 0,02137765 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,601E-03 0,02135559 ! macroautophagy GO:0016236 17 10 0,000 8,601E-03 0,02133357 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,601E-03 0,0213116 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,601E-03 0,02128968 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,601E-03 0,0212678 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,601E-03 0,02124596 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,601E-03 0,02122417 ! copper ion homeostasis GO:0055070 13 10 0,000 8,601E-03 0,02120242 ! regulation of bone resorption GO:0045124 25 10 0,000 8,601E-03 0,02118072 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,601E-03 0,02115907 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,601E-03 0,02113745 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,601E-03 0,02111588 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,601E-03 0,02109436 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,601E-03 0,02107288 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,601E-03 0,02105144 ! blastoderm segmentation GO:0007350 18 10 0,000 8,601E-03 0,02103005 ! response to dsRNA GO:0043331 20 10 0,000 8,601E-03 0,0210087 ! DNA ligation GO:0006266 19 10 0,000 8,601E-03 0,02098739 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,601E-03 0,02096613 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,601E-03 0,02094491 ! melanosome localization GO:0032400 16 10 0,000 8,601E-03 0,02092373 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,601E-03 0,02090259 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,601E-03 0,0208815 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,601E-03 0,02086045 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,601E-03 0,02083944 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 8,601E-03 0,02081848 ! mRNA cleavage GO:0006379 17 10 0,000 8,601E-03 0,02079755 ! protein sumoylation GO:0016925 15 10 0,000 8,601E-03 0,02077667 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,601E-03 0,02075583 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,601E-03 0,02073504 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,601E-03 0,02071428 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,601E-03 0,02069357 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,601E-03 0,02067289 ! salivary gland development GO:0007431 27 10 0,000 8,601E-03 0,02065226 ! prophase GO:0051324 15 10 0,000 8,601E-03 0,02063167 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,601E-03 0,02061112 ! apical protein localization GO:0045176 15 10 0,000 8,601E-03 0,02059061 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,601E-03 0,02057015 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,601E-03 0,02054972 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,601E-03 0,02052933 ! midbrain development GO:0030901 13 10 0,000 8,601E-03 0,02050899 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,601E-03 0,02048868 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,601E-03 0,02046841 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,601E-03 0,02044819 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,601E-03 0,020428 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,601E-03 0,02040786 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,601E-03 0,02038775 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 8,601E-03 0,02036768 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,601E-03 0,02034766 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,601E-03 0,02032767 ! oocyte development GO:0048599 17 10 0,000 8,601E-03 0,02030772 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,601E-03 0,02028781 ! blastocyst formation GO:0001825 17 10 0,000 8,601E-03 0,02026794 ! cerebellar cortex development GO:0021695 15 10 0,000 8,601E-03 0,02024811 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 8,601E-03 0,02022832 ! activation of innate immune response GO:0002218 12 10 0,000 8,601E-03 0,02020856 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 8,601E-03 0,02018885 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,601E-03 0,02016917 ! response to nicotine GO:0035094 20 10 0,000 8,601E-03 0,02014953 ! establishment of cell polarity GO:0030010 16 10 0,000 8,601E-03 0,02012993 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,601E-03 0,02011037 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,601E-03 0,02009084 ! localization within membrane GO:0051668 20 10 0,000 8,601E-03 0,02007135 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,457E-03 0,02204795 ! respiratory burst GO:0045730 17 11 0,000 9,457E-03 0,02202661 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,457E-03 0,0220053 ! neuron fate specification GO:0048665 17 11 0,000 9,457E-03 0,02198404 ! telencephalon cell migration GO:0022029 20 11 0,000 9,457E-03 0,02196282 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 9,457E-03 0,02194164 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,457E-03 0,02192051 ! thyroid gland development GO:0030878 26 11 0,000 9,457E-03 0,02189941 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,457E-03 0,02187835 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,457E-03 0,02185733 ! Golgi vesicle budding GO:0048194 22 11 0,000 9,457E-03 0,02183636 ! response to pain GO:0048265 24 11 0,000 9,457E-03 0,02181542 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,457E-03 0,02179453 ! T cell proliferation GO:0042098 26 11 0,000 9,457E-03 0,02177367 ! blood vessel remodeling GO:0001974 29 11 0,000 9,457E-03 0,02175285 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,457E-03 0,02173208 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 9,457E-03 0,02171134 ! bone resorption GO:0045453 16 11 0,000 9,457E-03 0,02169064 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,457E-03 0,02166999 ! ventral spinal cord development GO:0021517 21 11 0,000 9,457E-03 0,02164937 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,457E-03 0,02162879 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,457E-03 0,02160825 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,457E-03 0,02158775 ! melanocyte differentiation GO:0030318 21 11 0,000 9,457E-03 0,02156728 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,457E-03 0,02154686 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,457E-03 0,02152648 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,457E-03 0,02150613 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,457E-03 0,02148582 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,457E-03 0,02146555 ! lipid digestion GO:0044241 18 11 0,000 9,457E-03 0,02144532 ! substrate-bound cell migration GO:0006929 13 11 0,000 9,457E-03 0,02142513 ! UV protection GO:0009650 19 11 0,000 9,457E-03 0,02140497 ! adult heart development GO:0007512 14 11 0,000 9,457E-03 0,02138485 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,457E-03 0,02136477 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,457E-03 0,02134473 ! temperature homeostasis GO:0001659 17 11 0,000 9,457E-03 0,02132473 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,457E-03 0,02130476 ! negative regulation of ossification GO:0030279 26 11 0,000 9,457E-03 0,02128483 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,457E-03 0,02126494 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,457E-03 0,02124508 ! regulation of organ growth GO:0046620 13 11 0,000 9,457E-03 0,02122527 ! pigment granule localization GO:0051875 20 11 0,000 9,457E-03 0,02120548 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,457E-03 0,02118574 ! vasoconstriction GO:0042310 18 11 0,000 9,457E-03 0,02116603 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,457E-03 0,02114636 ! embryonic axis specification GO:0000578 18 11 0,000 9,457E-03 0,02112673 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,457E-03 0,02110713 ! snRNA metabolic process GO:0016073 24 11 0,000 9,457E-03 0,02108757 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,457E-03 0,02106804 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,457E-03 0,02104855 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,457E-03 0,0210291 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,457E-03 0,02100968 ! zymogen activation GO:0031638 15 11 0,000 9,457E-03 0,0209903 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,457E-03 0,02097095 ! neuroblast proliferation GO:0007405 24 11 0,000 9,457E-03 0,02095164 ! nucleosome positioning GO:0016584 15 11 0,000 9,457E-03 0,02093237 ! regulation of isotype switching GO:0045191 22 11 0,000 9,457E-03 0,02091313 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,457E-03 0,02089393 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,457E-03 0,02087476 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,457E-03 0,02085562 ! acid secretion GO:0046717 18 11 0,000 9,457E-03 0,02083652 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,457E-03 0,02081746 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,457E-03 0,02079843 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,457E-03 0,02077944 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,457E-03 0,02076048 ! oocyte differentiation GO:0009994 18 11 0,000 9,457E-03 0,02074155 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,457E-03 0,02072266 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 9,457E-03 0,02070381 ! cholesterol efflux GO:0033344 19 11 0,000 9,457E-03 0,02068499 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,457E-03 0,0206662 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,457E-03 0,02064745 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,457E-03 0,02062873 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,457E-03 0,02061004 ! embryonic gut development GO:0048566 15 11 0,000 9,457E-03 0,02059139 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,457E-03 0,02057277 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 9,457E-03 0,02055419 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,457E-03 0,02053564 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,457E-03 0,02051712 ! defense response to fungus GO:0050832 13 11 0,000 9,457E-03 0,02049864 ! developmental induction GO:0031128 19 11 0,000 9,457E-03 0,02048018 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 9,457E-03 0,02046177 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,457E-03 0,02044338 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,457E-03 0,02042503 ! sequestering of metal ion GO:0051238 14 11 0,000 9,457E-03 0,02040671 ! lamellipodium assembly GO:0030032 20 11 0,000 9,457E-03 0,02038843 ! regulation of embryonic development GO:0045995 27 11 0,000 9,457E-03 0,02037017 ! nucleus localization GO:0051647 19 11 0,000 9,457E-03 0,02035195 ! regulation of synapse organization GO:0050807 17 11 0,000 9,457E-03 0,02033377 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01031242 0,0221533 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01031242 0,02213354 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01031242 0,02211381 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01031242 0,02209412 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01031242 0,02207446 ! virus-host interaction GO:0019048 29 12 0,000 0,01031242 0,02205484 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01031242 0,02203525 ! cartilage condensation GO:0001502 20 12 0,000 0,01031242 0,0220157 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01031242 0,02199618 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01031242 0,0219767 ! protein complex disassembly GO:0043241 27 12 0,000 0,01031242 0,02195725 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01031242 0,02193784 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01031242 0,02191846 ! hippocampus development GO:0021766 26 12 0,000 0,01031242 0,02189911 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01031242 0,0218798 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01031242 0,02186052 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01031242 0,02184128 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01031242 0,02182207 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01031242 0,02180289 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01031242 0,02178375 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01031242 0,02176464 ! drug transport GO:0015893 16 12 0,000 0,01031242 0,02174557 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01031242 0,02172653 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01031242 0,02170752 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01031242 0,02168854 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01031242 0,0216696 ! focal adhesion formation GO:0048041 35 12 0,000 0,01031242 0,02165069 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01031242 0,02163182 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01031242 0,02161297 ! forebrain cell migration GO:0021885 21 12 0,000 0,01031242 0,02159416 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01031242 0,02157539 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01031242 0,02155664 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01031242 0,02153793 ! entry into host cell GO:0030260 32 12 0,000 0,01031242 0,02151925 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01031242 0,0215006 ! monoamine transport GO:0015844 18 12 0,000 0,01031242 0,02148199 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01031242 0,0214634 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01031242 0,02144485 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01031242 0,02142633 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01031242 0,02140785 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01031242 0,02138939 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01031242 0,02137097 ! protein homotetramerization GO:0051289 21 12 0,000 0,01031242 0,02135258 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01031242 0,02133422 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01031242 0,02131589 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01031242 0,02129759 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01031242 0,02127933 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01031242 0,02126109 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01031242 0,02124289 ! cranial nerve development GO:0021545 20 12 0,000 0,01031242 0,02122472 ! fucose catabolic process GO:0019317 22 12 0,000 0,01031242 0,02120658 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01031242 0,02118847 ! histone acetylation GO:0016573 26 12 0,000 0,01031242 0,02117039 ! histone methylation GO:0016571 26 12 0,000 0,01031242 0,02115234 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01031242 0,02113432 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01031242 0,02111633 ! gland morphogenesis GO:0022612 29 12 0,000 0,01031242 0,02109838 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01031242 0,02108045 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01031242 0,02106256 ! T cell homeostasis GO:0043029 25 12 0,000 0,01031242 0,02104469 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01031242 0,02102686 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01031242 0,02100905 ! spleen development GO:0048536 22 12 0,000 0,01031242 0,02099128 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01031242 0,02097354 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01031242 0,02095582 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01031242 0,02093814 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01031242 0,02092048 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01031242 0,02090286 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01031242 0,02088526 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01031242 0,0208677 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01031242 0,02085016 ! response to cold GO:0009409 17 12 0,000 0,01031242 0,02083266 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01031242 0,02081518 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01031242 0,02079773 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01116716 0,02250267 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01116716 0,02248384 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01116716 0,02246504 ! peroxisomal transport GO:0043574 24 13 0,000 0,01116716 0,02244628 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01116716 0,02242754 ! lipid localization GO:0010876 28 13 0,000 0,01116716 0,02240883 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01116716 0,02239016 ! organelle fusion GO:0048284 32 13 0,000 0,01116716 0,02237152 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01116716 0,02235291 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01116716 0,02233432 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01116716 0,02231577 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01116716 0,02229725 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01116716 0,02227877 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01116716 0,02226031 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01116716 0,02224188 ! methionine metabolic process GO:0006555 27 13 0,000 0,01116716 0,02222348 ! plasma membrane organization GO:0007009 24 13 0,000 0,01116716 0,02220512 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01116716 0,02218678 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01116716 0,02216848 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01116716 0,0221502 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01116716 0,02213195 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01116716 0,02211374 ! response to X-ray GO:0010165 25 13 0,000 0,01116716 0,02209555 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01116716 0,0220774 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01116716 0,02205927 ! exocrine system development GO:0035272 32 13 0,000 0,01116716 0,02204117 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01116716 0,02202311 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01116716 0,02200507 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01116716 0,02198706 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01116716 0,02196909 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01116716 0,02195114 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01116716 0,02193322 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01116716 0,02191533 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01116716 0,02189747 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01116716 0,02187964 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01116716 0,02186183 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01116716 0,02184406 ! ribosome assembly GO:0042255 17 13 0,000 0,01116716 0,02182631 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01116716 0,0218086 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01116716 0,02179091 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01116716 0,02177325 ! chromatin silencing GO:0006342 26 13 0,000 0,01116716 0,02175562 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01116716 0,02173802 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01116716 0,02172045 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01116716 0,0217029 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01116716 0,02168538 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01116716 0,0216679 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01116716 0,02165044 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01116716 0,021633 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01116716 0,0216156 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01116716 0,02159822 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01116716 0,02158088 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01116716 0,02156356 ! embryonic placenta development GO:0001892 23 13 0,000 0,01116716 0,02154626 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01116716 0,021529 ! insulin secretion GO:0030073 23 13 0,000 0,01116716 0,02151176 ! actin filament polymerization GO:0030041 24 13 0,000 0,01116716 0,02149455 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01116716 0,02147737 ! acrosome reaction GO:0007340 18 13 0,000 0,01116716 0,02146022 ! rRNA transcription GO:0009303 25 14 0,000 0,01202119 0,02308299 ! lactation GO:0007595 26 14 0,000 0,01202119 0,02306458 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01202119 0,0230462 ! reproductive cellular process GO:0048610 20 14 0,000 0,01202119 0,02302785 ! tRNA modification GO:0006400 20 14 0,000 0,01202119 0,02300953 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01202119 0,02299124 ! regulation of S phase GO:0033261 23 14 0,000 0,01202119 0,02297298 ! water transport GO:0006833 21 14 0,000 0,01202119 0,02295475 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01202119 0,02293654 ! non-recombinational repair GO:0000726 25 14 0,000 0,01202119 0,02291837 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01202119 0,02290022 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01202119 0,02288211 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01202119 0,02286402 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01202119 0,02284596 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01202119 0,02282793 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01202119 0,02280992 ! palate development GO:0060021 31 14 0,000 0,01202119 0,02279195 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01202119 0,022774 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01202119 0,02275608 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01202119 0,02273819 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01202119 0,02272033 ! arginine metabolic process GO:0006525 17 14 0,000 0,01202119 0,0227025 ! regulation of heart rate GO:0002027 24 14 0,000 0,01202119 0,02268469 ! organic alcohol transport GO:0015850 29 14 0,000 0,01202119 0,02266691 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01202119 0,02264916 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01202119 0,02263144 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01202119 0,02261375 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01202119 0,02259608 ! L-amino acid transport GO:0015807 30 14 0,000 0,01202119 0,02257844 ! bone mineralization GO:0030282 17 14 0,000 0,01202119 0,02256083 ! stem cell development GO:0048864 43 14 0,000 0,01202119 0,02254324 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01202119 0,02252569 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01202119 0,02250816 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01202119 0,02249066 ! cerebellum development GO:0021549 21 14 0,000 0,01202119 0,02247318 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01202119 0,02245573 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01202119 0,02243831 ! response to gamma radiation GO:0010332 28 14 0,000 0,01202119 0,02242092 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01202119 0,02240355 ! cofactor transport GO:0051181 26 14 0,000 0,01202119 0,02238621 ! NADP metabolic process GO:0006739 24 14 0,000 0,01202119 0,0223689 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01202119 0,02235161 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01202119 0,02233435 ! intestinal absorption GO:0050892 25 14 0,000 0,01202119 0,02231712 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01202119 0,02229991 ! oxygen transport GO:0015671 21 14 0,000 0,01202119 0,02228273 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01202119 0,02226558 ! male genitalia development GO:0030539 24 14 0,000 0,01202119 0,02224845 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01202119 0,02223135 ! regulation of axon extension GO:0030516 37 14 0,000 0,01202119 0,02221427 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01202119 0,02219722 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01287451 0,02375465 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01287451 0,02373645 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01287451 0,02371828 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01287451 0,02370013 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01287451 0,02368201 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01287451 0,02366392 ! copper ion transport GO:0006825 20 15 0,000 0,01287451 0,02364585 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01287451 0,02362782 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01287451 0,02360981 ! sulfate transport GO:0008272 23 15 0,000 0,01287451 0,02359183 ! response to cAMP GO:0051591 22 15 0,000 0,01287451 0,02357387 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01287451 0,02355594 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01287451 0,02353805 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01287451 0,02352017 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01287451 0,02350233 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01287451 0,02348451 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01287451 0,02346672 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01287451 0,02344895 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01287451 0,02343122 ! pituitary gland development GO:0021983 29 15 0,000 0,01287451 0,02341351 ! vesicle coating GO:0006901 33 15 0,000 0,01287451 0,02339582 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01287451 0,02337816 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01287451 0,02336053 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01287451 0,02334293 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01287451 0,02332535 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01287451 0,0233078 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01287451 0,02329028 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01287451 0,02327278 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01287451 0,02325531 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01287451 0,02323786 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01287451 0,02322044 ! histone deacetylation GO:0016575 20 15 0,000 0,01287451 0,02320305 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01287451 0,02318568 ! tissue regeneration GO:0042246 26 15 0,000 0,01287451 0,02316834 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01287451 0,02315102 ! water homeostasis GO:0030104 27 15 0,000 0,01287451 0,02313373 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01287451 0,02311647 ! muscle maintenance GO:0046716 26 15 0,000 0,01287451 0,02309923 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01287451 0,02308202 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01287451 0,02306483 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01287451 0,02304767 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01287451 0,02303053 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01287451 0,02301342 ! cell killing GO:0001906 29 15 0,000 0,01287451 0,02299634 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01287451 0,02297928 ! detection of bacterium GO:0016045 18 15 0,000 0,01287451 0,02296224 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01287451 0,02294524 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01287451 0,02292825 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01287451 0,02291129 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01287451 0,02289436 ! peptide hormone processing GO:0016486 23 15 0,000 0,01287451 0,02287745 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01372712 0,0243745 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01372712 0,02435652 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01372712 0,02433858 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01372712 0,02432065 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01372712 0,02430276 ! bone remodeling GO:0046849 27 16 0,000 0,01372712 0,02428489 ! filopodium assembly GO:0046847 32 16 0,000 0,01372712 0,02426704 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01372712 0,02424923 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01372712 0,02423144 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01372712 0,02421367 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01372712 0,02419593 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01372712 0,02417822 ! startle response GO:0001964 28 16 0,000 0,01372712 0,02416053 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01372712 0,02414287 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01372712 0,02412524 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01372712 0,02410763 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01372712 0,02409004 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01372712 0,02407248 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01372712 0,02405495 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01372712 0,02403744 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01372712 0,02401996 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01372712 0,0240025 ! response to osmotic stress GO:0006970 25 16 0,000 0,01372712 0,02398507 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01372712 0,02396767 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01372712 0,02395029 ! fructose metabolic process GO:0006000 25 16 0,000 0,01372712 0,02393293 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01372712 0,0239156 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01372712 0,0238983 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01372712 0,02388102 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01372712 0,02386376 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01372712 0,02384653 ! axon cargo transport GO:0008088 43 16 0,000 0,01372712 0,02382933 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01372712 0,02381215 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01372712 0,02379499 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01372712 0,02377786 ! DNA replication initiation GO:0006270 27 16 0,000 0,01372712 0,02376075 ! neuron recognition GO:0008038 35 16 0,000 0,01372712 0,02374367 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01372712 0,02372661 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01372712 0,02370958 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01372712 0,02369257 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01372712 0,02367559 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01372712 0,02365863 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01372712 0,02364169 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01372712 0,02362478 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01372712 0,0236079 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01372712 0,02359103 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01372712 0,02357419 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01372712 0,02355738 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01372712 0,02354059 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01372712 0,02352382 ! defense response to virus GO:0051607 37 16 0,000 0,01372712 0,02350708 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01457902 0,02494817 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01457902 0,02493044 ! metencephalon development GO:0022037 30 17 0,000 0,01457902 0,02491273 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01457902 0,02489505 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01457902 0,02487739 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01457902 0,02485976 ! signal complex assembly GO:0007172 41 17 0,000 0,01457902 0,02484215 ! endothelial cell migration GO:0043542 28 17 0,000 0,01457902 0,02482457 ! inositol metabolic process GO:0006020 28 17 0,000 0,01457902 0,02480702 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01457902 0,02478949 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01457902 0,02477198 ! glial cell development GO:0021782 27 17 0,000 0,01457902 0,0247545 ! limbic system development GO:0021761 36 17 0,000 0,01457902 0,02473704 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01457902 0,02471961 ! adult walking behavior GO:0007628 33 17 0,000 0,01457902 0,0247022 ! heart looping GO:0001947 30 17 0,000 0,01457902 0,02468482 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01457902 0,02466746 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01457902 0,02465012 ! myoblast differentiation GO:0045445 45 17 0,000 0,01457902 0,02463281 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01457902 0,02461552 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01457902 0,02459826 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01457902 0,02458102 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01457902 0,02456381 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01457902 0,02454662 ! glycine metabolic process GO:0006544 28 17 0,000 0,01457902 0,02452946 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01457902 0,02451231 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01457902 0,0244952 ! NAD metabolic process GO:0019674 29 17 0,000 0,01457902 0,0244781 ! membrane budding GO:0006900 37 17 0,000 0,01457902 0,02446103 ! DNA integration GO:0015074 29 17 0,000 0,01457902 0,02444399 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01457902 0,02442697 ! regulation of protein binding GO:0043393 33 17 0,000 0,01457902 0,02440997 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01457902 0,02439299 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01457902 0,02437604 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01457902 0,02435911 ! genitalia development GO:0048806 30 17 0,000 0,01457902 0,02434221 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01457902 0,02432533 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01457902 0,02430847 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01457902 0,02429164 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01457902 0,02427483 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01457902 0,02425804 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01457902 0,02424127 ! steroid catabolic process GO:0006706 31 17 0,000 0,01457902 0,02422453 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01457902 0,02420781 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01457902 0,02419112 ! gas transport GO:0015669 25 17 0,000 0,01457902 0,02417445 ! organic cation transport GO:0015695 31 17 0,000 0,01457902 0,0241578 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01457902 0,02414117 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01457902 0,02412457 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01457902 0,02410799 ! microspike assembly GO:0030035 36 17 0,000 0,01457902 0,02409143 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01457902 0,0240749 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01457902 0,02405838 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01543021 0,02544558 ! neuron maturation GO:0042551 42 18 0,000 0,01543021 0,02542815 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01543021 0,02541074 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01543021 0,02539336 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01543021 0,02537601 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01543021 0,02535867 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01543021 0,02534136 ! memory GO:0007613 31 18 0,000 0,01543021 0,02532408 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01543021 0,02530681 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01543021 0,02528957 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01543021 0,02527236 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01543021 0,02525517 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01543021 0,025238 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01543021 0,02522085 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01543021 0,02520373 ! response to retinoic acid GO:0032526 26 18 0,000 0,01543021 0,02518663 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01543021 0,02516956 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01543021 0,0251525 ! response to fungus GO:0009620 21 18 0,000 0,01543021 0,02513547 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01543021 0,02511847 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01543021 0,02510148 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01543021 0,02508452 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01543021 0,02506759 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01543021 0,02505067 ! vitamin transport GO:0051180 27 18 0,000 0,01543021 0,02503378 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01543021 0,02501691 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01543021 0,02500006 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01543021 0,02498324 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01543021 0,02496644 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01543021 0,02494966 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01543021 0,02493291 ! nerve development GO:0021675 28 18 0,000 0,01543021 0,02491617 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01543021 0,02489946 ! protein secretion GO:0009306 39 19 0,000 0,0162807 0,02625427 ! positive regulation of translation GO:0045727 30 19 0,000 0,0162807 0,02623668 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0162807 0,02621912 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0162807 0,02620158 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0162807 0,02618407 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0162807 0,02616658 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0162807 0,02614911 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0162807 0,02613167 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0162807 0,02611425 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0162807 0,02609685 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0162807 0,02607947 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0162807 0,02606212 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0162807 0,02604479 ! cerebral cortex development GO:0021987 36 19 0,000 0,0162807 0,02602749 ! pigmentation during development GO:0048066 41 19 0,000 0,0162807 0,0260102 ! response to vitamin A GO:0033189 27 19 0,000 0,0162807 0,02599294 ! heme metabolic process GO:0042168 36 19 0,000 0,0162807 0,02597571 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0162807 0,02595849 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0162807 0,0259413 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0162807 0,02592413 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0162807 0,02590699 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0162807 0,02588987 ! peptide cross-linking GO:0018149 37 19 0,000 0,0162807 0,02587277 ! protein export from nucleus GO:0006611 36 19 0,000 0,0162807 0,02585569 ! heart process GO:0003015 30 19 0,000 0,0162807 0,02583863 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0162807 0,0258216 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0162807 0,02580459 ! visual learning GO:0008542 36 19 0,000 0,0162807 0,0257876 ! cellular pigmentation GO:0033059 36 19 0,000 0,0162807 0,02577064 ! G1 phase GO:0051318 40 19 0,000 0,0162807 0,02575369 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0162807 0,02573677 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0162807 0,02571987 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0162807 0,025703 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0162807 0,02568614 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0162807 0,02566931 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0162807 0,0256525 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0162807 0,02563571 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0162807 0,02561895 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0162807 0,0256022 ! cilium assembly GO:0042384 37 19 0,000 0,0162807 0,02558548 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0162807 0,02556878 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01713048 0,02688581 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01713048 0,02686828 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01713048 0,02685078 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01713048 0,02683329 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01713048 0,02681584 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01713048 0,0267984 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01713048 0,02678099 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01713048 0,0267636 ! response to vitamin GO:0033273 31 20 0,000 0,01713048 0,02674623 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01713048 0,02672888 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01713048 0,02671156 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01713048 0,02669426 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01713048 0,02667698 ! response to alkaloid GO:0043279 38 20 0,000 0,01713048 0,02665973 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01713048 0,0266425 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01713048 0,02662528 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01713048 0,0266081 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01713048 0,02659093 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01713048 0,02657378 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01713048 0,02655666 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01713048 0,02653956 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01713048 0,02652248 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01713048 0,02650543 ! body fluid secretion GO:0007589 31 20 0,000 0,01713048 0,02648839 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01713048 0,02647138 ! peptide secretion GO:0002790 35 20 0,000 0,01713048 0,02645439 ! stem cell differentiation GO:0048863 53 20 0,000 0,01713048 0,02643742 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01713048 0,02642047 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01713048 0,02640355 ! sensory perception of pain GO:0019233 30 20 0,000 0,01713048 0,02638665 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01713048 0,02636976 ! diencephalon development GO:0021536 34 20 0,000 0,01713048 0,0263529 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01713048 0,02633606 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01713048 0,02631925 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01713048 0,02630245 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01713048 0,02628568 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01713048 0,02626892 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01713048 0,02625219 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01713048 0,02623548 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01713048 0,02621879 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01713048 0,02620212 ! regulation of glucose import GO:0046324 29 20 0,000 0,01713048 0,02618548 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01713048 0,02616885 ! actin filament-based movement GO:0030048 43 20 0,000 0,01713048 0,02615225 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01713048 0,02613566 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01713048 0,0261191 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01713048 0,02610256 ! negative regulation of translation GO:0017148 29 20 0,000 0,01713048 0,02608604 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01713048 0,02606954 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01713048 0,02605306 ! regulation of cell killing GO:0031341 42 21 0,000 0,01797956 0,02732711 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01797956 0,02730986 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01797956 0,02729263 ! hormone secretion GO:0046879 38 21 0,000 0,01797956 0,02727542 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01797956 0,02725823 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01797956 0,02724107 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01797956 0,02722392 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01797956 0,0272068 ! axis specification GO:0009798 38 21 0,000 0,01797956 0,0271897 ! ovarian follicle development GO:0001541 35 21 0,000 0,01797956 0,02717262 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01797956 0,02715556 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01797956 0,02713853 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01797956 0,02712151 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01797956 0,02710452 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01797956 0,02708755 ! cell aging GO:0007569 44 21 0,000 0,01797956 0,0270706 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01797956 0,02705367 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01797956 0,02703676 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01797956 0,02701987 ! cytolysis GO:0019835 24 21 0,000 0,01797956 0,02700301 ! vasodilation GO:0042311 39 21 0,000 0,01797956 0,02698616 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01797956 0,02696934 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01797956 0,02695253 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01797956 0,02693575 ! oogenesis GO:0048477 36 21 0,000 0,01797956 0,02691899 ! DNA modification GO:0006304 34 21 0,000 0,01797956 0,02690225 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01797956 0,02688553 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01797956 0,02686883 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01797956 0,02685215 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01797956 0,02683549 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01797956 0,02681886 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01797956 0,02680224 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01797956 0,02678564 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01797956 0,02676907 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01797956 0,02675251 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01797956 0,02673598 ! collagen catabolic process GO:0030574 28 21 0,000 0,01797956 0,02671947 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01797956 0,02670297 ! gut development GO:0048565 39 21 0,000 0,01797956 0,0266865 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01882793 0,02792848 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01882793 0,02791127 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01882793 0,02789408 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01882793 0,02787692 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01882793 0,02785977 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01882793 0,02784265 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01882793 0,02782555 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01882793 0,02780847 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01882793 0,02779141 ! regeneration GO:0031099 41 22 0,000 0,01882793 0,02777437 ! keratinization GO:0031424 28 22 0,000 0,01882793 0,02775735 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01882793 0,02774035 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01882793 0,02772337 ! sensory perception of taste GO:0050909 28 22 0,000 0,01882793 0,02770642 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01882793 0,02768948 ! vacuolar transport GO:0007034 36 22 0,000 0,01882793 0,02767257 ! lysosome organization GO:0007040 41 22 0,000 0,01882793 0,02765567 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01882793 0,0276388 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01882793 0,02762195 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01882793 0,02760511 ! fucose metabolic process GO:0006004 39 22 0,000 0,01882793 0,0275883 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01882793 0,02757151 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01882793 0,02755474 ! ureteric bud development GO:0001657 43 22 0,000 0,01882793 0,02753799 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01882793 0,02752126 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01882793 0,02750455 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01882793 0,02748786 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01882793 0,02747119 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01882793 0,02745454 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01882793 0,02743791 ! sarcomere organization GO:0045214 30 22 0,000 0,01882793 0,0274213 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01882793 0,02740471 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01882793 0,02738815 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01882793 0,0273716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01882793 0,02735507 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01882793 0,02733856 ! protein stabilization GO:0050821 39 22 0,000 0,01882793 0,02732207 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01967559 0,02853494 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01967559 0,02851776 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01967559 0,02850059 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01967559 0,02848344 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01967559 0,02846631 ! gluconeogenesis GO:0006094 33 23 0,000 0,01967559 0,0284492 ! viral genome replication GO:0019079 41 23 0,000 0,01967559 0,02843212 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01967559 0,02841505 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01967559 0,028398 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01967559 0,02838098 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01967559 0,02836397 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01967559 0,02834699 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01967559 0,02833003 ! visual behavior GO:0007632 42 23 0,000 0,01967559 0,02831308 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01967559 0,02829616 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01967559 0,02827926 ! response to ethanol GO:0045471 46 23 0,000 0,01967559 0,02826237 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01967559 0,02824551 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01967559 0,02822867 ! peroxisome organization GO:0007031 37 23 0,000 0,01967559 0,02821184 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01967559 0,02819504 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01967559 0,02817826 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01967559 0,0281615 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01967559 0,02814475 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01967559 0,02812803 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01967559 0,02811133 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01967559 0,02809464 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01967559 0,02807798 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01967559 0,02806134 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01967559 0,02804471 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01967559 0,02802811 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01967559 0,02801152 ! fatty acid transport GO:0015908 44 23 0,000 0,01967559 0,02799496 ! platelet activation GO:0030168 37 23 0,000 0,01967559 0,02797841 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01967559 0,02796189 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01967559 0,02794538 ! hormone transport GO:0009914 40 23 0,000 0,01967559 0,02792889 ! cell-cell recognition GO:0009988 25 23 0,000 0,01967559 0,02791243 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01967559 0,02789598 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01967559 0,02787955 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01967559 0,02786314 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01967559 0,02784675 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01967559 0,02783038 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02052255 0,02901132 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02052255 0,02899428 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02052255 0,02897727 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02052255 0,02896027 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02052255 0,02894329 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02052255 0,02892634 ! vesicle docking GO:0048278 47 24 0,000 0,02052255 0,0289094 ! spinal cord development GO:0021510 47 24 0,000 0,02052255 0,02889249 ! vacuole organization GO:0007033 43 24 0,000 0,02052255 0,02887559 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02052255 0,02885871 ! digestive system process GO:0022600 39 24 0,000 0,02052255 0,02884186 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02052255 0,02882502 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02052255 0,0288082 ! regulation of behavior GO:0050795 43 24 0,000 0,02052255 0,02879141 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02052255 0,02877463 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02052255 0,02875787 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02052255 0,02874113 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02052255 0,02872441 ! membrane depolarization GO:0051899 39 24 0,000 0,02052255 0,02870771 ! pallium development GO:0021543 49 24 0,000 0,02052255 0,02869103 ! pentose metabolic process GO:0019321 35 24 0,000 0,02052255 0,02867437 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02052255 0,02865773 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02052255 0,0286411 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02052255 0,0286245 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02052255 0,02860791 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02052255 0,02859135 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02052255 0,0285748 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02052255 0,02855828 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02052255 0,02854177 ! regulation of amine transport GO:0051952 40 24 0,000 0,02052255 0,02852528 ! protein tetramerization GO:0051262 52 24 0,000 0,02052255 0,02850881 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02136881 0,02966726 ! myelination GO:0042552 45 25 0,000 0,02136881 0,02965015 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02136881 0,02963306 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02136881 0,02961599 ! phototransduction GO:0007602 33 25 0,000 0,02136881 0,02959894 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02136881 0,02958191 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02136881 0,0295649 ! sperm motility GO:0030317 31 25 0,000 0,02136881 0,02954791 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02136881 0,02953093 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02136881 0,02951398 ! receptor metabolic process GO:0043112 46 25 0,000 0,02136881 0,02949705 ! chromosome condensation GO:0030261 45 25 0,000 0,02136881 0,02948013 ! response to starvation GO:0042594 42 25 0,000 0,02136881 0,02946324 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02136881 0,02944637 ! neural crest cell development GO:0014032 54 25 0,000 0,02136881 0,02942951 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02136881 0,02941267 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02136881 0,02939586 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02136881 0,02937906 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02136881 0,02936228 ! interaction with host GO:0051701 62 25 0,000 0,02136881 0,02934552 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02136881 0,02932878 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02136881 0,02931206 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02136881 0,02929536 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02136881 0,02927868 ! immunoglobulin production GO:0002377 55 25 0,000 0,02136881 0,02926201 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02136881 0,02924537 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02136881 0,02922874 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02136881 0,02921213 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02136881 0,02919555 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02136881 0,02917898 ! telomere organization GO:0032200 43 25 0,000 0,02136881 0,02916243 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02136881 0,02914589 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02136881 0,02912938 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02221436 0,03026487 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02221436 0,03024774 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02221436 0,03023063 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02221436 0,03021354 ! initiation of viral infection GO:0019059 57 26 0,000 0,02221436 0,03019647 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02221436 0,03017942 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02221436 0,03016239 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02221436 0,03014538 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02221436 0,03012839 ! molting cycle process GO:0022404 50 26 0,000 0,02221436 0,03011141 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02221436 0,03009446 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02221436 0,03007752 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02221436 0,03006061 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02221436 0,03004371 ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02221436 0,03002683 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02221436 0,03000997 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02221436 0,02999313 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02221436 0,02997631 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02221436 0,02995951 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02221436 0,02994272 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02221436 0,02992596 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02221436 0,02990921 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02221436 0,02989248 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02221436 0,02987577 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02221436 0,02985908 ! blastocyst development GO:0001824 49 26 0,000 0,02221436 0,02984241 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02221436 0,02982576 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02221436 0,02980912 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02221436 0,02979251 ! neuron fate commitment GO:0048663 48 27 0,000 0,02305921 0,03090834 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02305921 0,03089113 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02305921 0,03087394 ! iron ion transport GO:0006826 59 27 0,000 0,02305921 0,03085677 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02305921 0,03083962 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02305921 0,03082248 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02305921 0,03080537 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02305921 0,03078827 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02305921 0,0307712 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02305921 0,03075414 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02305921 0,0307371 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02305921 0,03072008 ! autophagy GO:0006914 41 27 0,000 0,02305921 0,03070308 ! male gonad development GO:0008584 44 27 0,000 0,02305921 0,0306861 ! response to toxin GO:0009636 47 27 0,000 0,02305921 0,03066914 ! primary neural tube formation GO:0014020 51 27 0,000 0,02305921 0,03065219 ! base-excision repair GO:0006284 41 27 0,000 0,02305921 0,03063527 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02305921 0,03061836 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02305921 0,03060147 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02305921 0,0305846 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02305921 0,03056775 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02305921 0,03055092 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02305921 0,03053411 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02305921 0,03051731 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02305921 0,03050053 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02390336 0,03159972 ! circadian rhythm GO:0007623 50 28 0,000 0,02390336 0,03158237 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02390336 0,03156504 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02390336 0,03154772 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02390336 0,03153042 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02390336 0,03151315 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02390336 0,03149589 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02390336 0,03147865 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02390336 0,03146143 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02390336 0,03144423 ! synaptogenesis GO:0007416 42 28 0,000 0,02390336 0,03142705 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02390336 0,03140988 ! lipid oxidation GO:0034440 43 28 0,000 0,02390336 0,03139274 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02390336 0,03137561 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02390336 0,0313585 ! translational initiation GO:0006413 65 29 0,000 0,02474681 0,03244732 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02474681 0,03242965 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02474681 0,03241199 ! regulation of pH GO:0006885 43 29 0,000 0,02474681 0,03239436 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02474681 0,03237674 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02474681 0,03235915 ! catechol metabolic process GO:0009712 54 29 0,000 0,02474681 0,03234157 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02474681 0,03232401 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02474681 0,03230647 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02474681 0,03228895 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02474681 0,03227145 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02474681 0,03225397 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02474681 0,03223651 ! cell fate determination GO:0001709 60 29 0,000 0,02474681 0,03221906 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02474681 0,03220164 ! detection of light stimulus GO:0009583 38 29 0,000 0,02474681 0,03218423 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02474681 0,03216685 ! tissue homeostasis GO:0001894 48 29 0,000 0,02474681 0,03214948 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02474681 0,03213213 ! phenol metabolic process GO:0018958 55 30 0,000 0,02558956 0,03320846 ! zinc ion transport GO:0006829 45 30 0,000 0,02558956 0,03319056 ! membrane docking GO:0022406 61 30 0,000 0,02558956 0,03317267 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02558956 0,03315481 ! cell junction assembly GO:0034329 78 30 0,000 0,02558956 0,03313697 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02558956 0,03311914 ! acute-phase response GO:0006953 49 30 0,000 0,02558956 0,03310133 ! myofibril assembly GO:0030239 47 30 0,000 0,02558956 0,03308355 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02558956 0,03306578 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02558956 0,03304803 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02558956 0,0330303 ! phospholipid transport GO:0015914 51 30 0,000 0,02558956 0,03301259 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02558956 0,0329949 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02558956 0,03297723 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02558956 0,03295957 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02558956 0,03294194 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02558956 0,03292432 ! eye morphogenesis GO:0048592 60 30 0,000 0,02558956 0,03290672 ! response to heat GO:0009408 50 30 0,000 0,02558956 0,03288915 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02643161 0,03395326 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02643161 0,03393514 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02643161 0,03391704 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02643161 0,03389896 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02643161 0,0338809 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02643161 0,03386286 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02643161 0,03384484 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02643161 0,03382683 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02643161 0,03380885 ! ovulation cycle process GO:0022602 49 31 0,000 0,02643161 0,03379089 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02643161 0,03377294 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02643161 0,03375501 ! peptide transport GO:0015833 55 31 0,000 0,02643161 0,03373711 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02643161 0,03371922 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02643161 0,03370135 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02643161 0,0336835 ! mesoderm formation GO:0001707 69 31 0,000 0,02643161 0,03366567 ! natural killer cell activation GO:0030101 45 31 0,000 0,02643161 0,03364786 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02643161 0,03363006 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02643161 0,03361229 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02643161 0,03359453 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02643161 0,03357679 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02643161 0,03355907 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02727295 0,03460903 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02727295 0,03459079 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02727295 0,03457257 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02727295 0,03455436 ! cholesterol transport GO:0030301 56 32 0,000 0,02727295 0,03453617 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02727295 0,03451801 ! spliceosome assembly GO:0000245 67 32 0,000 0,02727295 0,03449986 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02727295 0,03448173 ! metanephros development GO:0001656 74 32 0,000 0,02727295 0,03446362 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02727295 0,03444553 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02727295 0,03442745 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02727295 0,0344094 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02727295 0,03439137 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02727295 0,03437335 ! muscle cell development GO:0055001 49 32 0,000 0,02727295 0,03435536 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02727295 0,03433738 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02727295 0,03431942 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02727295 0,03430148 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02727295 0,03428356 ! ovulation cycle GO:0042698 51 32 0,000 0,02727295 0,03426565 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02727295 0,03424777 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02727295 0,03422991 ! hindbrain development GO:0030902 61 32 0,000 0,02727295 0,03421206 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02727295 0,03419423 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02727295 0,03417642 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02727295 0,03415863 ! gene silencing GO:0016458 65 32 0,000 0,02727295 0,03414086 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0281136 0,0351749 ! post-embryonic development GO:0009791 69 33 0,000 0,0281136 0,03515662 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0281136 0,03513835 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0281136 0,03512011 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0281136 0,03510188 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0281136 0,03508368 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0281136 0,03506549 ! cell fate specification GO:0001708 52 33 0,000 0,0281136 0,03504732 ! sterol transport GO:0015918 57 33 0,000 0,0281136 0,03502917 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0281136 0,03501104 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0281136 0,03499293 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0281136 0,03497483 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0281136 0,03495676 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0281136 0,0349387 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02895355 0,03596399 ! glial cell differentiation GO:0010001 63 34 0,000 0,02895355 0,03594543 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02895355 0,03592689 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02895355 0,03590837 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02895355 0,03588987 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02895355 0,03587139 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02895355 0,03585293 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02895355 0,03583449 ! mismatch repair GO:0006298 46 34 0,000 0,02895355 0,03581607 ! spermatid development GO:0007286 63 34 0,000 0,02895355 0,03579766 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02895355 0,03577927 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02895355 0,03576091 ! placenta development GO:0001890 53 34 0,000 0,02895355 0,03574256 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02895355 0,03572423 ! regulation of muscle development GO:0048634 70 35 0,000 0,0297928 0,0367409 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0297928 0,03672207 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0297928 0,03670327 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0297928 0,03668449 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0297928 0,03666572 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0297928 0,03664698 ! odontogenesis GO:0042476 66 35 0,000 0,0297928 0,03662825 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0297928 0,03660954 ! female gonad development GO:0008585 58 35 0,000 0,0297928 0,03659086 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0297928 0,03657219 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0297928 0,03655354 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0297928 0,03653491 ! cytokine production GO:0001816 59 35 0,000 0,0297928 0,03651629 ! neural tube formation GO:0001841 67 35 0,000 0,0297928 0,0364977 ! vesicle localization GO:0051648 64 35 0,000 0,0297928 0,03647913 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03063136 0,0374868 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03063136 0,03746774 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03063136 0,0374487 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03063136 0,03742968 ! cell junction organization GO:0034330 86 36 0,000 0,03063136 0,03741068 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03063136 0,0373917 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03063136 0,03737274 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03063136 0,0373538 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03063136 0,03733488 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03063136 0,03731597 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03063136 0,03729709 ! aerobic respiration GO:0009060 55 36 0,000 0,03063136 0,03727822 ! embryonic organ development GO:0048568 57 36 0,000 0,03063136 0,03725938 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03063136 0,03724055 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03063136 0,03722174 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03146922 0,03822056 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03146922 0,03820128 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03146922 0,03818201 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03146922 0,03816277 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03146922 0,03814354 ! organic anion transport GO:0015711 68 37 0,000 0,03146922 0,03812434 ! tissue remodeling GO:0048771 76 37 0,000 0,03146922 0,03810515 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03146922 0,03808598 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03146922 0,03806683 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03146922 0,0380477 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03146922 0,0380286 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03146922 0,0380095 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03146922 0,03799043 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03146922 0,03797138 ! pigment metabolic process GO:0042440 80 37 0,000 0,03146922 0,03795235 ! spermatid differentiation GO:0048515 66 37 0,000 0,03146922 0,03793333 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03146922 0,03791434 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03230638 0,03890347 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03230638 0,03888401 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03230638 0,03886457 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03230638 0,03884515 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03230638 0,03882575 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03230638 0,03880636 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03230638 0,038787 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03230638 0,03876765 ! lipid homeostasis GO:0055088 67 38 0,000 0,03230638 0,03874833 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03230638 0,03872902 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03230638 0,03870973 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03230638 0,03869046 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03230638 0,03867121 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03230638 0,03865199 ! glucan metabolic process GO:0044042 62 38 0,000 0,03230638 0,03863277 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03314284 0,03961335 ! mammary gland development GO:0030879 86 39 0,000 0,03314284 0,03959368 ! learning GO:0007612 77 39 0,000 0,03314284 0,03957403 ! ear morphogenesis GO:0042471 60 39 0,000 0,03314284 0,0395544 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03314284 0,03953479 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03314284 0,0395152 ! segmentation GO:0035282 67 39 0,000 0,03314284 0,03949563 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03314284 0,03947608 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03314284 0,03945654 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03314284 0,03943703 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03314284 0,03941754 ! RNA modification GO:0009451 57 39 0,000 0,03314284 0,03939806 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03314284 0,03937861 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03397861 0,0403517 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03397861 0,04033179 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03397861 0,0403119 ! feeding behavior GO:0007631 59 40 0,000 0,03397861 0,04029204 ! negative regulation of binding GO:0051100 72 40 0,000 0,03397861 0,04027219 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03397861 0,04025236 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03397861 0,04023255 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03397861 0,04021276 ! maintenance of protein location GO:0045185 91 40 0,000 0,03397861 0,04019299 ! cytokinesis GO:0000910 72 40 0,000 0,03397861 0,04017324 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03481369 0,04114034 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03481369 0,04112014 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03481369 0,04109997 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03481369 0,04107981 ! gliogenesis GO:0042063 88 41 0,000 0,03481369 0,04105967 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03481369 0,04103955 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03481369 0,04101946 ! T cell differentiation GO:0030217 81 41 0,000 0,03481369 0,04099938 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03481369 0,04097932 ! female gamete generation GO:0007292 61 41 0,000 0,03481369 0,04095928 ! polyol metabolic process GO:0019751 66 41 0,000 0,03481369 0,04093926 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03481369 0,04091926 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03564807 0,04187952 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03564807 0,04185908 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03564807 0,04183866 ! regulation of tube size GO:0035150 71 42 0,000 0,03564807 0,04181826 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03564807 0,04179788 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03564807 0,04177752 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03564807 0,04175718 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03564807 0,04173686 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03564807 0,04171656 ! neuron migration GO:0001764 79 42 0,000 0,03564807 0,04169628 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03564807 0,04167602 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03564807 0,04165578 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03648176 0,04260927 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03648176 0,0425886 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03648176 0,04256795 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03648176 0,04254731 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03648176 0,0425267 ! glucose transport GO:0015758 65 43 0,000 0,03648176 0,0425061 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03648176 0,04248553 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03648176 0,04246497 ! neural tube development GO:0021915 77 43 0,000 0,03648176 0,04244444 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03648176 0,04242393 ! striated muscle contraction GO:0006941 77 43 0,000 0,03648176 0,04240343 ! phagocytosis GO:0006909 90 43 0,000 0,03648176 0,04238296 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03648176 0,0423625 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03731475 0,04330887 ! hexose transport GO:0008645 67 44 0,000 0,03731475 0,04328799 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03731475 0,04326713 ! male sex differentiation GO:0046661 76 44 0,000 0,03731475 0,04324628 ! biopolymer methylation GO:0043414 84 44 0,000 0,03731475 0,04322546 ! B cell differentiation GO:0030183 107 44 0,000 0,03731475 0,04320466 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03731475 0,04318388 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03731475 0,04316312 ! developmental growth GO:0048589 82 44 0,000 0,03731475 0,04314238 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03731475 0,04312166 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03814705 0,04406232 ! glycolysis GO:0006096 65 45 0,000 0,03814705 0,04404117 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03814705 0,04402005 ! leukocyte migration GO:0050900 68 45 0,000 0,03814705 0,04399895 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03814705 0,04397787 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03814705 0,0439568 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03814705 0,04393576 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03814705 0,04391474 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03814705 0,04389374 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03814705 0,04387276 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03814705 0,04385179 ! cell growth GO:0016049 84 45 0,000 0,03814705 0,04383085 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03897866 0,04476499 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03897866 0,04474364 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03897866 0,0447223 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03897866 0,04470098 ! pigmentation GO:0043473 100 46 0,000 0,03897866 0,04467969 ! response to insulin stimulus GO:0032868 95 46 0,000 0,03897866 0,04465841 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03897866 0,04463715 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03980958 0,04556701 ! endosome transport GO:0016197 108 47 0,000 0,03980958 0,04554534 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03980958 0,04552369 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03980958 0,04550207 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03980958 0,04548046 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03980958 0,04545888 ! JNK cascade GO:0007254 91 47 0,000 0,03980958 0,04543731 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03980958 0,04541577 ! methylation GO:0032259 90 47 0,000 0,03980958 0,04539424 ! protein homooligomerization GO:0051260 76 47 0,000 0,03980958 0,04537274 ! mitochondrial transport GO:0006839 82 48 0,000 0,04063981 0,04629705 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04063981 0,04627514 ! cellular component disassembly GO:0022411 86 48 0,000 0,04063981 0,04625325 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04063981 0,04623138 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04063981 0,04620954 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04063981 0,04618771 ! activation of caspase activity GO:0006919 84 48 0,000 0,04063981 0,0461659 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04063981 0,04614411 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04063981 0,04612235 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04063981 0,0461006 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04146935 0,04701944 ! regulation of action potential GO:0001508 95 49 0,000 0,04146935 0,04699729 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04146935 0,04697516 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04146935 0,04695306 ! regulation of ion transport GO:0043269 77 49 0,000 0,04146935 0,04693097 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04146935 0,04690891 ! peptide metabolic process GO:0006518 76 49 0,000 0,04146935 0,04688686 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04146935 0,04686484 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04146935 0,04684284 ! endocrine system development GO:0035270 104 49 0,000 0,04146935 0,04682086 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04146935 0,0467989 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04146935 0,04677696 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04146935 0,04675504 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04146935 0,04673314 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04229819 0,04764488 ! neuromuscular process GO:0050905 99 50 0,000 0,04229819 0,04762258 ! regulation of ossification GO:0030278 117 50 0,000 0,04229819 0,04760031 ! inner ear development GO:0048839 79 50 0,000 0,04229819 0,04757805 ! histone modification GO:0016570 91 50 0,000 0,04229819 0,04755582 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04229819 0,04753361 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04229819 0,04751142 ! positive regulation of binding GO:0051099 78 51 0,000 0,04312635 0,04841904 ! viral infectious cycle GO:0019058 99 51 0,000 0,04312635 0,04839646 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04312635 0,04837389 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04312635 0,04835135 ! excretion GO:0007588 83 51 0,000 0,04312635 0,04832883 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04312635 0,04830633 ! chromatin remodeling GO:0006338 109 51 0,000 0,04312635 0,04828385 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04312635 0,0482614 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04312635 0,04823896 ! vesicle organization GO:0016050 107 51 0,000 0,04312635 0,04821654 ! regulation of cell shape GO:0008360 125 51 0,000 0,04312635 0,04819415 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04312635 0,04817177 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04395382 0,04907327 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04395382 0,04905051 ! membrane fusion GO:0006944 110 52 0,000 0,04395382 0,04902777 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04395382 0,04900505 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04395382 0,04898235 ! amino acid activation GO:0043038 92 52 0,000 0,04395382 0,04895967 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04395382 0,04893702 ! synapse organization GO:0050808 85 52 0,000 0,04395382 0,04891438 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0447806 0,04981143 ! RNA catabolic process GO:0006401 93 53 0,000 0,0447806 0,04978842 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0447806 0,04976542 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0447806 0,04974244 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0447806 0,04971949 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0447806 0,04969656 ! cell maturation GO:0048469 100 53 0,000 0,0447806 0,04967364 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0447806 0,04965075 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0447806 0,04962788 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0456067 0,05052013 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0456067 0,05049688 ! cell recognition GO:0008037 85 54 0,000 0,0456067 0,05047365 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0456067 0,05045044 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0456067 0,05042726 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0456067 0,0504041 ! chloride transport GO:0006821 90 55 0,000 0,04643211 0,05129277 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04643211 0,05126923 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04643211 0,05124571 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04643211 0,05122221 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04643211 0,05119874 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04643211 0,05117529 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04643211 0,05115185 ! aging GO:0007568 103 55 0,000 0,04643211 0,05112844 ! gastrulation GO:0007369 112 55 0,000 0,04643211 0,05110505 ! heart morphogenesis GO:0003007 97 55 0,000 0,04643211 0,05108169 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04643211 0,05105834 ! RNA elongation GO:0006354 79 55 0,000 0,04643211 0,05103501 ! nuclear export GO:0051168 97 55 0,000 0,04643211 0,05101171 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04643211 0,05098843 ! regulation of actin filament length GO:0030832 105 56 0,000 0,04725683 0,0518704 ! sensory perception of smell GO:0007608 80 56 0,000 0,04725683 0,05184675 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,04725683 0,05182312 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,04725683 0,05179951 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,04725683 0,05177592 ! regulation of DNA replication GO:0006275 101 56 0,000 0,04725683 0,05175236 ! proton transport GO:0015992 94 56 0,000 0,04725683 0,05172881 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,04725683 0,05170529 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04808086 0,05258298 ! muscle fiber development GO:0048747 112 57 0,000 0,04808086 0,05255909 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04808086 0,05253522 ! lipid modification GO:0030258 97 57 0,000 0,04808086 0,05251137 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04808086 0,05248755 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04808086 0,05246374 ! maintenance of location GO:0051235 118 57 0,000 0,04808086 0,05243996 ! hydrogen transport GO:0006818 97 58 0,000 0,04890421 0,05331379 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04890421 0,05328964 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04890421 0,05326552 ! adult behavior GO:0030534 99 58 0,000 0,04890421 0,05324142 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04890421 0,05321734 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04972688 0,0540881 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04972688 0,05406365 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,04972688 0,05403924 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,04972688 0,05401484 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,04972688 0,05399046 ! DNA catabolic process GO:0006308 86 59 0,000 0,04972688 0,05396611 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04972688 0,05394178 ! establishment of organelle localization GO:0051656 109 59 0,000 0,04972688 0,05391747 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05054886 0,05478403 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05054886 0,05475937 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05054886 0,05473472 ! camera-type eye development GO:0043010 116 60 0,000 0,05054886 0,0547101 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05054886 0,0546855 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05054886 0,05466092 ! kidney development GO:0001822 122 60 0,000 0,05054886 0,05463637 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,05137016 0,05549914 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,05137016 0,05547423 ! mesoderm development GO:0007498 119 61 0,000 0,05137016 0,05544935 ! tRNA processing GO:0008033 89 61 0,000 0,05137016 0,05542448 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,05137016 0,05539964 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,05137016 0,05537482 ! ear development GO:0043583 103 62 0,000 0,05219077 0,05623421 ! viral reproductive process GO:0022415 126 62 0,000 0,05219077 0,05620904 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05219077 0,05618389 ! gonad development GO:0008406 98 62 0,000 0,05219077 0,05615876 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05219077 0,05613366 ! regulation of mitosis GO:0007088 105 63 0,000 0,0530107 0,05699006 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,0530107 0,0569646 ! detection of external stimulus GO:0009581 91 63 0,000 0,0530107 0,05693917 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,0530107 0,05691376 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05382995 0,05776756 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05382995 0,0577418 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05382995 0,05771607 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05382995 0,05769036 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05382995 0,05766468 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05382995 0,05763901 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05464852 0,05848947 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05464852 0,05846347 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05464852 0,05843748 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05464852 0,05841152 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05464852 0,05838558 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05546641 0,0592331 ! actin filament organization GO:0007015 148 66 0,000 0,05546641 0,05920682 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05546641 0,05918056 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05546641 0,05915433 ! secondary metabolic process GO:0019748 116 66 0,000 0,05546641 0,05912812 ! developmental maturation GO:0021700 116 66 0,000 0,05546641 0,05910194 ! cell projection assembly GO:0030031 120 66 0,000 0,05546641 0,05907577 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05628361 0,05991963 ! activation of MAPK activity GO:0000187 115 67 0,000 0,05628361 0,05989313 ! lung development GO:0030324 144 67 0,000 0,05628361 0,05986665 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,05628361 0,0598402 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05628361 0,05981377 ! hexose catabolic process GO:0019320 104 67 0,000 0,05628361 0,05978736 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05628361 0,05976098 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05628361 0,05973461 ! adaptive immune response GO:0002250 119 67 0,000 0,05628361 0,05970828 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05628361 0,05968196 ! amino acid transport GO:0006865 125 68 0,000 0,05710014 0,06052112 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05710014 0,06049447 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05710014 0,06046784 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,05710014 0,06044124 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05710014 0,06041466 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05710014 0,0603881 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05791599 0,06122402 ! urogenital system development GO:0001655 137 69 0,000 0,05791599 0,06119713 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05791599 0,06117026 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05791599 0,06114342 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05791599 0,06111661 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05873115 0,06194965 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05873115 0,06192251 ! amine catabolic process GO:0009310 117 71 0,000 0,05954564 0,06275375 ! reproductive structure development GO:0048608 113 71 0,000 0,05954564 0,06272628 ! appendage development GO:0048736 136 71 0,000 0,05954564 0,06269883 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05954564 0,0626714 ! B cell activation GO:0042113 160 71 0,000 0,05954564 0,062644 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05954564 0,06261662 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05954564 0,06258926 ! acute inflammatory response GO:0002526 113 72 0,000 0,06035946 0,06341697 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06035946 0,06338929 ! carbohydrate transport GO:0008643 110 72 0,000 0,06035946 0,06336163 ! respiratory system development GO:0060541 153 72 0,000 0,06035946 0,063334 ! learning or memory GO:0007611 147 73 0,000 0,06117259 0,06415922 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06117259 0,06413127 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06117259 0,06410334 ! axon guidance GO:0007411 139 73 0,000 0,06117259 0,06407543 ! fertilization GO:0009566 90 73 0,000 0,06117259 0,06404754 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06198505 0,06486996 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06198505 0,06484175 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06198505 0,06481357 ! exocytosis GO:0006887 133 74 0,000 0,06198505 0,06478542 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,06198505 0,06475729 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06198505 0,06472918 ! eye development GO:0001654 143 74 0,000 0,06198505 0,0647011 ! organelle localization GO:0051640 136 74 0,000 0,06198505 0,06467304 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06279683 0,06549163 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06279683 0,06546325 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06279683 0,0654349 ! rhythmic process GO:0048511 128 75 0,000 0,06279683 0,06540657 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06279683 0,06537827 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06360794 0,06619408 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06360794 0,06616546 ! defense response to bacterium GO:0042742 89 76 0,000 0,06360794 0,06613687 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06360794 0,0661083 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,06360794 0,06607975 ! regulation of catabolic process GO:0009894 161 76 0,000 0,06360794 0,06605123 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06441837 0,06686394 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,06441837 0,0668351 ! blood coagulation GO:0007596 146 78 0,000 0,06522813 0,06764607 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06522813 0,06761693 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06603722 0,06842616 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06603722 0,0683967 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06603722 0,06836727 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06603722 0,06833787 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06684563 0,0691447 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06684563 0,06911499 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06684563 0,0690853 ! protein import into nucleus GO:0006606 158 80 0,000 0,06684563 0,06905564 ! inorganic anion transport GO:0015698 138 80 0,000 0,06684563 0,069026 ! T cell activation GO:0042110 168 81 0,000 0,06765336 0,06983011 ! response to hypoxia GO:0001666 171 81 0,000 0,06765336 0,06980017 ! digestion GO:0007586 112 81 0,000 0,06765336 0,06977025 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06765336 0,06974036 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06765336 0,06971049 ! nuclear import GO:0051170 161 81 0,000 0,06765336 0,06968065 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06765336 0,06965083 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06846043 0,07045158 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06846043 0,07042146 ! response to drug GO:0042493 143 82 0,000 0,06846043 0,07039136 ! response to nutrient GO:0007584 125 82 0,000 0,06846043 0,07036129 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06846043 0,07033125 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06846043 0,07030123 ! response to oxygen levels GO:0070482 176 83 0,000 0,06926682 0,07109896 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06926682 0,07106865 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07007254 0,07186468 ! hemostasis GO:0007599 158 84 0,000 0,07007254 0,07183406 ! negative regulation of transport GO:0051051 153 84 0,000 0,07007254 0,07180347 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07007254 0,0717729 ! nucleosome assembly GO:0006334 122 85 0,000 0,0708776 0,07256659 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0708776 0,07253573 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07168198 0,07332774 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07168198 0,07329657 ! chromatin assembly GO:0031497 124 86 0,000 0,07168198 0,07326544 ! tube morphogenesis GO:0035239 176 86 0,000 0,07168198 0,07323433 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07168198 0,07320324 ! amine transport GO:0015837 155 86 0,000 0,07168198 0,07317218 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07248569 0,07396122 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07248569 0,07392987 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07248569 0,07389855 ! regulation of protein transport GO:0051223 154 87 0,000 0,07248569 0,07386725 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,07328873 0,07465397 ! regulation of DNA binding GO:0051101 155 88 0,000 0,07328873 0,07462238 ! gland development GO:0048732 206 88 0,000 0,07328873 0,07459082 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07328873 0,07455928 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07328873 0,07452776 ! cellular defense response GO:0006968 114 89 0,000 0,07409111 0,07531187 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07409111 0,07528007 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,07409111 0,07524829 ! ossification GO:0001503 188 90 0,000 0,07489281 0,07603042 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07489281 0,07599836 ! sex differentiation GO:0007548 145 90 0,000 0,07489281 0,07596632 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07489281 0,0759343 ! bone development GO:0060348 189 91 0,000 0,07569385 0,07671416 ! sterol metabolic process GO:0016125 152 91 0,000 0,07569385 0,07668185 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,07569385 0,07664958 ! regulation of defense response GO:0031347 149 92 0,000 0,07649422 0,07742747 ! nucleosome organization GO:0034728 138 92 0,000 0,07649422 0,07739491 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07649422 0,07736238 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07649422 0,07732987 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,07729393 0,0781055 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,07729393 0,07807271 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,07729393 0,07803995 ! regulation of membrane potential GO:0042391 164 93 0,000 0,07729393 0,07800721 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,07729393 0,0779745 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,07809297 0,07874756 ! female pregnancy GO:0007565 164 94 0,000 0,07809297 0,07871457 ! transcription initiation GO:0006352 153 94 0,000 0,07809297 0,07868161 ! regulation of T cell activation GO:0050863 158 94 0,000 0,07809297 0,07864867 ! forebrain development GO:0030900 188 95 0,000 0,07889134 0,07941948 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,07889134 0,07938627 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07968905 0,08015546 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07968905 0,08012196 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07968905 0,08008849 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07968905 0,08005505 ! detection of stimulus GO:0051606 151 96 0,000 0,07968905 0,08002164 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08048609 0,0807883 ! protein ubiquitination GO:0016567 217 97 0,000 0,08048609 0,08075461 ! hormone metabolic process GO:0042445 157 97 0,000 0,08048609 0,08072094 ! regulation of protein localization GO:0032880 176 97 0,000 0,08048609 0,08068731 ! response to virus GO:0009615 160 98 0,000 0,08128248 0,08145174 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08128248 0,08141783 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08128248 0,08138395 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08207819 0,08214648 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,08207819 0,08211232 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,08207819 0,08207819 GO:0060538|skeletal muscle organ development,