pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/1894-2-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! embryonic forelimb morphogenesis GO:0035115 8 8 1,000 7,091E-06 0,0130691 ! forelimb morphogenesis GO:0035136 10 10 1,000 1,139E-05 0,01049788 ! hindbrain development GO:0030902 11 11 1,000 1,392E-05 8,552E-03 ! proximal/distal pattern formation GO:0009954 11 11 1,000 1,392E-05 6,414E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 1,973E-05 7,274E-03 ! pigmentation GO:0043473 17 17 1,000 3,438E-05 0,01056129 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 4,321E-05 0,01137781 ! neural tube development GO:0021915 21 20 1,000 4,801E-05 0,01105961 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 5,834E-05 0,0119475 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 1,587E-04 0,02924601 GO:0035113|embryonic appendage morphogenesis, ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 1,677E-04 0,02810109 ! limb development GO:0060173 39 39 1,000 1,865E-04 0,02864902 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 2,166E-04 0,03070995 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,379E-04 0,0313194 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,489E-04 0,03058509 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,602E-04 0,02997103 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,602E-04 0,02820803 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 2,835E-04 0,02902344 ! regulation of ligase activity GO:0051340 50 49 1,000 2,955E-04 0,02866035 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 3,077E-04 0,02835629 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 3,077E-04 0,02700599 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 3,33E-04 0,02789299 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,587E-04 0,03675667 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regionalization GO:0003002 70 69 1,000 5,871E-04 0,04508712 ! negative regulation of signal transduction GO:0009968 71 71 1,000 6,217E-04 0,0458303 ! negative regulation of cell communication GO:0010648 76 76 1,000 7,123E-04 0,05049104 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 7,502E-04 0,0512112 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 9,982E-04 0,0657053 ! brain development GO:0007420 91 90 1,000 9,982E-04 0,0634396 ! pattern specification process GO:0007389 96 94 1,000 1,089E-03 0,0668769 ! anti-apoptosis GO:0006916 100 99 1,000 1,207E-03 0,07175659 ! rRNA transcription GO:0009303 5 5 0,000 2,904E-03 0,1672777 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 2,904E-03 0,16220868 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 2,904E-03 0,15743784 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 2,904E-03 0,15293962 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 2,904E-03 0,14869129 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 2,904E-03 0,14467261 ! reproductive cellular process GO:0048610 5 5 0,000 2,904E-03 0,14086543 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 2,904E-03 0,1372535 ! negative regulation of blood pressure GO:0045776 6 5 0,000 2,904E-03 0,13382216 ! prostate gland development GO:0030850 5 5 0,000 2,904E-03 0,13055821 ! metencephalon development GO:0022037 5 5 0,000 2,904E-03 0,12744968 ! water transport GO:0006833 5 5 0,000 2,904E-03 0,12448573 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 2,904E-03 0,12165651 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 2,904E-03 0,11895303 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 2,904E-03 0,1163671 ! glycerol metabolic process GO:0006071 5 5 0,000 2,904E-03 0,1138912 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 2,904E-03 0,11151847 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 2,904E-03 0,10924258 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 2,904E-03 0,10705773 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 2,904E-03 0,10495856 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 2,904E-03 0,10294013 ! filopodium assembly GO:0046847 7 5 0,000 2,904E-03 0,10099786 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 2,904E-03 0,09912753 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 2,904E-03 0,09732521 ! GTP metabolic process GO:0046039 5 5 0,000 2,904E-03 0,09558726 ! establishment of tissue polarity GO:0007164 5 5 0,000 2,904E-03 0,09391029 ! mRNA stabilization GO:0048255 5 5 0,000 2,904E-03 0,09229115 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 2,904E-03 0,09072689 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 2,904E-03 0,08921478 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 2,904E-03 0,08775224 ! social behavior GO:0035176 5 5 0,000 2,904E-03 0,08633688 ! macrophage chemotaxis GO:0048246 6 5 0,000 2,904E-03 0,08496645 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 2,904E-03 0,08363885 ! memory GO:0007613 5 5 0,000 2,904E-03 0,0823521 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 2,904E-03 0,08110434 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 2,904E-03 0,07989383 ! membrane hyperpolarization GO:0060081 5 5 0,000 2,904E-03 0,07871892 ! response to lipid GO:0033993 5 5 0,000 2,904E-03 0,07757807 ! erythrocyte maturation GO:0043249 5 5 0,000 2,904E-03 0,07646981 ! hippocampus development GO:0021766 6 5 0,000 2,904E-03 0,07539277 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 2,904E-03 0,07434565 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 2,904E-03 0,07332721 ! middle ear morphogenesis GO:0042474 5 5 0,000 2,904E-03 0,0723363 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 2,904E-03 0,07137182 ! mechanosensory behavior GO:0007638 5 5 0,000 2,904E-03 0,07043272 ! heart looping GO:0001947 5 5 0,000 2,904E-03 0,06951801 ! negative regulation of endocytosis GO:0045806 5 5 0,000 2,904E-03 0,06862675 ! response to interferon-gamma GO:0034341 5 5 0,000 2,904E-03 0,06775806 ! pseudouridine synthesis GO:0001522 5 5 0,000 2,904E-03 0,06691108 ! endocrine pancreas development GO:0031018 5 5 0,000 2,904E-03 0,06608502 ! pH reduction GO:0045851 5 5 0,000 2,904E-03 0,0652791 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 2,904E-03 0,06449261 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 2,904E-03 0,06372484 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 2,904E-03 0,06297514 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 2,904E-03 0,06224287 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 2,904E-03 0,06152743 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 2,904E-03 0,06082826 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 2,904E-03 0,06014479 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 2,904E-03 0,05947652 ! adrenal gland development GO:0030325 5 5 0,000 2,904E-03 0,05882293 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 2,904E-03 0,05818355 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 2,904E-03 0,05755792 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 2,904E-03 0,0569456 ! astrocyte differentiation GO:0048708 5 5 0,000 2,904E-03 0,05634617 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 2,904E-03 0,05575923 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 2,904E-03 0,0551844 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 2,904E-03 0,05462129 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 2,904E-03 0,05406956 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 2,904E-03 0,05352887 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 2,904E-03 0,05299888 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 2,904E-03 0,05247928 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 2,904E-03 0,05196977 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 2,904E-03 0,05147006 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 2,904E-03 0,05097987 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 2,904E-03 0,05049893 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 2,904E-03 0,05002698 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 2,904E-03 0,04956376 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 2,904E-03 0,04910905 ! response to ATP GO:0033198 5 5 0,000 2,904E-03 0,0486626 ! regulation of type I interferon production GO:0032479 5 5 0,000 2,904E-03 0,0482242 ! regulation of appetite GO:0032098 5 5 0,000 2,904E-03 0,04779363 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 2,904E-03 0,04737068 ! paraxial mesoderm development GO:0048339 5 5 0,000 2,904E-03 0,04695514 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 2,904E-03 0,04654684 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 2,904E-03 0,04614557 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 2,904E-03 0,04575117 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 2,904E-03 0,04536345 ! receptor clustering GO:0043113 5 5 0,000 2,904E-03 0,04498224 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 2,904E-03 0,04460739 ! fear response GO:0042596 5 5 0,000 2,904E-03 0,04423873 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 2,904E-03 0,04387612 ! lens development in camera-type eye GO:0002088 5 5 0,000 2,904E-03 0,0435194 ! retinol metabolic process GO:0042572 5 5 0,000 2,904E-03 0,04316844 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 2,904E-03 0,04282309 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 2,904E-03 0,04248323 ! positive regulation of exocytosis GO:0045921 6 5 0,000 2,904E-03 0,04214871 ! parturition GO:0007567 5 5 0,000 2,904E-03 0,04181943 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,904E-03 0,04149524 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 2,904E-03 0,04117605 ! Schwann cell differentiation GO:0014037 5 5 0,000 2,904E-03 0,04086173 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 2,904E-03 0,04055217 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 2,904E-03 0,04024727 ! protein heterooligomerization GO:0051291 5 5 0,000 2,904E-03 0,03994691 ! regulation of gliogenesis GO:0014013 5 5 0,000 2,904E-03 0,03965101 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 2,904E-03 0,03935946 ! response to UV-B GO:0010224 5 5 0,000 2,904E-03 0,03907216 ! oligodendrocyte development GO:0014003 5 5 0,000 2,904E-03 0,03878903 ! hyaluronan metabolic process GO:0030212 5 5 0,000 2,904E-03 0,03850998 ! activated T cell proliferation GO:0050798 5 5 0,000 2,904E-03 0,0382349 ! interaction with symbiont GO:0051702 5 5 0,000 2,904E-03 0,03796373 ! cellular extravasation GO:0045123 5 5 0,000 2,904E-03 0,03769638 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 2,904E-03 0,03743277 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 2,904E-03 0,03717282 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 2,904E-03 0,03691646 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 2,904E-03 0,03666361 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 2,904E-03 0,03641419 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 2,904E-03 0,03616815 ! response to amine stimulus GO:0014075 5 5 0,000 2,904E-03 0,03592541 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 2,904E-03 0,03568591 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 2,904E-03 0,03544958 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 2,904E-03 0,03521636 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 2,904E-03 0,03498619 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 2,904E-03 0,034759 ! neuron recognition GO:0008038 5 5 0,000 2,904E-03 0,03453475 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 2,904E-03 0,03431338 ! decidualization GO:0046697 5 5 0,000 2,904E-03 0,03409482 ! hair follicle maturation GO:0048820 5 5 0,000 2,904E-03 0,03387903 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 2,904E-03 0,03366595 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 2,904E-03 0,03345554 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 2,904E-03 0,03324774 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 2,904E-03 0,03304251 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 2,904E-03 0,03283979 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 2,904E-03 0,03263955 ! postreplication repair GO:0006301 5 5 0,000 2,904E-03 0,03244174 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 2,904E-03 0,0322463 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 2,904E-03 0,03205321 ! histone methylation GO:0016571 5 5 0,000 2,904E-03 0,03186242 ! DNA methylation GO:0006306 5 5 0,000 2,904E-03 0,03167388 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 2,904E-03 0,03148757 ! T cell lineage commitment GO:0002360 5 5 0,000 2,904E-03 0,03130343 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 2,904E-03 0,03112143 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 2,904E-03 0,03094154 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 2,904E-03 0,03076372 ! intracellular cholesterol transport GO:0032367 5 5 0,000 2,904E-03 0,03058792 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 2,904E-03 0,03041413 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 2,904E-03 0,0302423 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 2,904E-03 0,0300724 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 2,904E-03 0,02990439 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 2,904E-03 0,02973826 ! sterol catabolic process GO:0016127 5 5 0,000 2,904E-03 0,02957396 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 2,904E-03 0,02941146 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 2,904E-03 0,02925075 ! detection of biotic stimulus GO:0009595 5 5 0,000 2,904E-03 0,02909177 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 2,904E-03 0,02893452 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 2,904E-03 0,02877896 ! zymogen activation GO:0031638 5 5 0,000 2,904E-03 0,02862506 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 2,904E-03 0,0284728 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 2,904E-03 0,02832215 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 2,904E-03 0,02817309 ! peptidyl-lysine modification GO:0018205 5 5 0,000 2,904E-03 0,02802558 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 2,904E-03 0,02787962 ! peptidyl-histidine modification GO:0018202 5 5 0,000 2,904E-03 0,02773516 ! nucleosome positioning GO:0016584 5 5 0,000 2,904E-03 0,0275922 ! regulation of isotype switching GO:0045191 5 5 0,000 2,904E-03 0,0274507 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 2,904E-03 0,02731065 ! negative regulation of neurological system process GO:0031645 5 5 0,000 2,904E-03 0,02717201 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 2,904E-03 0,02703478 ! glutathione biosynthetic process GO:0006750 5 5 0,000 2,904E-03 0,02689893 ! NADPH regeneration GO:0006740 5 5 0,000 2,904E-03 0,02676443 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 2,904E-03 0,02663128 ! positive regulation of epidermis development GO:0045684 5 5 0,000 2,904E-03 0,02649944 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 2,904E-03 0,0263689 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 2,904E-03 0,02623964 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 2,904E-03 0,02611164 ! sarcomere organization GO:0045214 5 5 0,000 2,904E-03 0,02598489 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 2,904E-03 0,02585936 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 2,904E-03 0,02573503 ! negative regulation of glucose transport GO:0010829 5 5 0,000 2,904E-03 0,0256119 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 2,904E-03 0,02548994 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 2,904E-03 0,02536913 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 2,904E-03 0,02524946 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 2,904E-03 0,02513092 ! spleen development GO:0048536 5 5 0,000 2,904E-03 0,02501349 ! male genitalia development GO:0030539 5 5 0,000 2,904E-03 0,02489715 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 2,904E-03 0,02478188 ! quaternary ammonium group transport GO:0015697 5 5 0,000 2,904E-03 0,02466768 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 2,904E-03 0,02455453 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 2,904E-03 0,0244424 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 2,904E-03 0,0243313 ! removal of superoxide radicals GO:0019430 6 5 0,000 2,904E-03 0,02422121 ! myeloid cell homeostasis GO:0002262 5 5 0,000 2,904E-03 0,0241121 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 2,904E-03 0,02400398 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 2,904E-03 0,02389681 ! ATP catabolic process GO:0006200 5 5 0,000 2,904E-03 0,02379061 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 2,904E-03 0,02368534 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 2,904E-03 0,023581 ! blastocyst formation GO:0001825 5 5 0,000 2,904E-03 0,02347757 ! regulation of fibrinolysis GO:0051917 5 5 0,000 2,904E-03 0,02337505 ! embryonic gut development GO:0048566 5 5 0,000 2,904E-03 0,02327342 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 2,904E-03 0,02317267 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 2,904E-03 0,02307279 ! activation of innate immune response GO:0002218 5 5 0,000 2,904E-03 0,02297376 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 2,904E-03 0,02287558 ! catecholamine transport GO:0051937 5 5 0,000 2,904E-03 0,02277824 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 2,904E-03 0,02268172 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 2,904E-03 0,02258602 ! muscle adaptation GO:0043500 5 5 0,000 2,904E-03 0,02249112 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 2,904E-03 0,02239701 ! embryonic heart tube development GO:0035050 5 5 0,000 2,904E-03 0,02230369 ! cardiac cell differentiation GO:0035051 6 5 0,000 2,904E-03 0,02221115 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 2,904E-03 0,02211937 ! defense response to fungus GO:0050832 5 5 0,000 2,904E-03 0,02202834 ! lysogeny GO:0030069 5 5 0,000 2,904E-03 0,02193806 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 2,904E-03 0,02184852 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 2,904E-03 0,0217597 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 2,904E-03 0,02167161 ! response to nicotine GO:0035094 5 5 0,000 2,904E-03 0,02158422 ! establishment of cell polarity GO:0030010 5 5 0,000 2,904E-03 0,02149754 ! mitochondrion localization GO:0051646 5 5 0,000 2,904E-03 0,02141155 ! nucleus localization GO:0051647 5 5 0,000 2,904E-03 0,02132624 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 2,904E-03 0,02124161 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 3,485E-03 0,02538365 ! axon extension GO:0048675 7 6 0,000 3,485E-03 0,02528371 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 3,485E-03 0,02518456 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 3,485E-03 0,02508618 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 3,485E-03 0,02498857 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 3,485E-03 0,02489172 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 3,485E-03 0,02479561 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 3,485E-03 0,02470024 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 3,485E-03 0,02460561 ! virus-host interaction GO:0019048 6 6 0,000 3,485E-03 0,02451169 ! regulation of S phase GO:0033261 6 6 0,000 3,485E-03 0,02441849 ! myotube differentiation GO:0014902 6 6 0,000 3,485E-03 0,024326 ! regulation of B cell proliferation GO:0030888 6 6 0,000 3,485E-03 0,0242342 ! bone remodeling GO:0046849 6 6 0,000 3,485E-03 0,02414309 ! N-glycan processing GO:0006491 6 6 0,000 3,485E-03 0,02405267 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 3,485E-03 0,02396292 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 3,485E-03 0,02387384 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 3,485E-03 0,02378542 ! retina development in camera-type eye GO:0060041 6 6 0,000 3,485E-03 0,02369765 ! RNA methylation GO:0001510 6 6 0,000 3,485E-03 0,02361053 ! cartilage condensation GO:0001502 7 6 0,000 3,485E-03 0,02352404 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 3,485E-03 0,02343819 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 3,485E-03 0,02335296 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 3,485E-03 0,02326834 ! artery development GO:0060840 6 6 0,000 3,485E-03 0,02318434 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 3,485E-03 0,02310095 ! bile acid metabolic process GO:0008206 6 6 0,000 3,485E-03 0,02301815 ! androgen metabolic process GO:0008209 6 6 0,000 3,485E-03 0,02293594 ! estrogen metabolic process GO:0008210 6 6 0,000 3,485E-03 0,02285432 ! limbic system development GO:0021761 7 6 0,000 3,485E-03 0,02277327 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 3,485E-03 0,0226928 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 3,485E-03 0,0226129 ! positive regulation of heart contraction GO:0045823 6 6 0,000 3,485E-03 0,02253355 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 3,485E-03 0,02245477 ! pathogenesis GO:0009405 6 6 0,000 3,485E-03 0,02237653 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 3,485E-03 0,02229883 ! positive regulation of cell growth GO:0030307 6 6 0,000 3,485E-03 0,02222167 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 3,485E-03 0,02214504 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 3,485E-03 0,02206895 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 3,485E-03 0,02199337 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 3,485E-03 0,0219183 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 3,485E-03 0,02184375 ! arginine metabolic process GO:0006525 6 6 0,000 3,485E-03 0,02176971 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 3,485E-03 0,02169616 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 3,485E-03 0,02162311 ! glutamate catabolic process GO:0006538 7 6 0,000 3,485E-03 0,02155055 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 3,485E-03 0,02147847 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 3,485E-03 0,02140688 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 3,485E-03 0,02133576 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 3,485E-03 0,02126511 ! ER overload response GO:0006983 6 6 0,000 3,485E-03 0,02119493 ! V(D)J recombination GO:0033151 6 6 0,000 3,485E-03 0,02112521 ! focal adhesion formation GO:0048041 7 6 0,000 3,485E-03 0,02105594 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 3,485E-03 0,02098713 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 3,485E-03 0,02091877 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 3,485E-03 0,02085085 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 3,485E-03 0,02078338 ! regulation of heart rate GO:0002027 6 6 0,000 3,485E-03 0,02071633 ! lipid digestion GO:0044241 6 6 0,000 3,485E-03 0,02064972 ! asymmetric protein localization GO:0008105 6 6 0,000 3,485E-03 0,02058354 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 3,485E-03 0,02051777 ! phagocytosis, engulfment GO:0006911 6 6 0,000 3,485E-03 0,02045243 ! Rac protein signal transduction GO:0016601 6 6 0,000 3,485E-03 0,0203875 ! regulation of vascular permeability GO:0043114 6 6 0,000 3,485E-03 0,02032298 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 3,485E-03 0,02025887 ! ruffle organization GO:0031529 6 6 0,000 3,485E-03 0,02019517 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 3,485E-03 0,02013186 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 3,485E-03 0,02006895 ! retinoic acid metabolic process GO:0042573 6 6 0,000 3,485E-03 0,02000643 ! neutral amino acid transport GO:0015804 6 6 0,000 3,485E-03 0,0199443 ! L-amino acid transport GO:0015807 6 6 0,000 3,485E-03 0,01988255 ! bone mineralization GO:0030282 6 6 0,000 3,485E-03 0,01982118 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 3,485E-03 0,01976019 ! negative regulation of ossification GO:0030279 6 6 0,000 3,485E-03 0,01969958 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 3,485E-03 0,01963934 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 3,485E-03 0,01957946 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 3,485E-03 0,01951995 ! purine base biosynthetic process GO:0009113 6 6 0,000 3,485E-03 0,0194608 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 3,485E-03 0,019402 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 3,485E-03 0,01934356 ! regulation of phagocytosis GO:0050764 6 6 0,000 3,485E-03 0,01928547 ! regulation of organ growth GO:0046620 6 6 0,000 3,485E-03 0,01922773 ! regulation of circadian rhythm GO:0042752 6 6 0,000 3,485E-03 0,01917034 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 3,485E-03 0,01911328 ! response to dsRNA GO:0043331 6 6 0,000 3,485E-03 0,01905657 ! DNA unwinding during replication GO:0006268 6 6 0,000 3,485E-03 0,01900019 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 3,485E-03 0,01894414 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 3,485E-03 0,01888842 ! genitalia development GO:0048806 6 6 0,000 3,485E-03 0,01883303 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 3,485E-03 0,01877796 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 3,485E-03 0,01872322 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 3,485E-03 0,01866879 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 3,485E-03 0,01861468 ! multicellular organismal aging GO:0010259 6 6 0,000 3,485E-03 0,01856088 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 3,485E-03 0,01850739 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 3,485E-03 0,0184542 ! erythrocyte development GO:0048821 6 6 0,000 3,485E-03 0,01840133 ! renal water homeostasis GO:0003091 6 6 0,000 3,485E-03 0,01834875 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 3,485E-03 0,01829648 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 3,485E-03 0,0182445 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 3,485E-03 0,01819281 ! ribosome assembly GO:0042255 6 6 0,000 3,485E-03 0,01814142 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 3,485E-03 0,01809032 ! diencephalon development GO:0021536 6 6 0,000 3,485E-03 0,0180395 ! fucose catabolic process GO:0019317 6 6 0,000 3,485E-03 0,01798897 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 3,485E-03 0,01793872 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 3,485E-03 0,01788875 ! regulation of lipid transport GO:0032368 6 6 0,000 3,485E-03 0,01783906 ! regulation of cell division GO:0051302 6 6 0,000 3,485E-03 0,01778965 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 3,485E-03 0,01774051 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 3,485E-03 0,01769163 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 3,485E-03 0,01764303 ! salivary gland morphogenesis GO:0007435 6 6 0,000 3,485E-03 0,01759469 ! neuroblast proliferation GO:0007405 6 6 0,000 3,485E-03 0,01754662 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 3,485E-03 0,01749881 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 3,485E-03 0,01745126 ! regulation of glucose transport GO:0010827 6 6 0,000 3,485E-03 0,01740396 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 3,485E-03 0,01735693 ! methionine biosynthetic process GO:0009086 6 6 0,000 3,485E-03 0,01731014 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 3,485E-03 0,01726361 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 3,485E-03 0,01721733 ! thymus development GO:0048538 6 6 0,000 3,485E-03 0,01717129 ! lymph node development GO:0048535 6 6 0,000 3,485E-03 0,0171255 ! organic cation transport GO:0015695 6 6 0,000 3,485E-03 0,01707995 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 3,485E-03 0,01703465 ! regulation of RNA splicing GO:0043484 6 6 0,000 3,485E-03 0,01698958 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 3,485E-03 0,01694476 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 3,485E-03 0,01690017 ! sperm-egg recognition GO:0035036 7 6 0,000 3,485E-03 0,01685581 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 3,485E-03 0,01681168 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 3,485E-03 0,01676779 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 3,485E-03 0,01672412 ! alditol metabolic process GO:0019400 6 6 0,000 3,485E-03 0,01668068 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 3,485E-03 0,01663747 ! regulation of amino acid transport GO:0051955 6 6 0,000 3,485E-03 0,01659448 ! maternal placenta development GO:0001893 6 6 0,000 3,485E-03 0,01655171 ! regulation of embryonic development GO:0045995 6 6 0,000 3,485E-03 0,01650916 ! negative regulation of immune effector process GO:0002698 6 6 0,000 3,485E-03 0,01646683 ! localization within membrane GO:0051668 6 6 0,000 3,485E-03 0,01642471 ! respiratory burst GO:0045730 7 7 0,000 4,064E-03 0,01910911 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 4,064E-03 0,01906049 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 4,064E-03 0,01901211 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 4,064E-03 0,01896398 ! positive regulation of blood pressure GO:0045777 7 7 0,000 4,064E-03 0,01891609 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 4,064E-03 0,01886845 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 4,064E-03 0,01882104 ! regulation of chemokine production GO:0032642 7 7 0,000 4,064E-03 0,01877387 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 4,064E-03 0,01872693 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 4,064E-03 0,01868023 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 4,064E-03 0,01863376 ! cellular protein complex disassembly GO:0043624 8 7 0,000 4,064E-03 0,01858753 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 4,064E-03 0,01854152 ! gene silencing by RNA GO:0031047 7 7 0,000 4,064E-03 0,01849574 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 4,064E-03 0,01845018 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 4,064E-03 0,01840485 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 4,064E-03 0,01835974 ! keratinocyte proliferation GO:0043616 7 7 0,000 4,064E-03 0,01831485 ! axis specification GO:0009798 7 7 0,000 4,064E-03 0,01827018 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 4,064E-03 0,01822572 ! visual behavior GO:0007632 7 7 0,000 4,064E-03 0,01818149 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 4,064E-03 0,01813746 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 4,064E-03 0,01809365 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 4,064E-03 0,01805006 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 4,064E-03 0,01800667 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 4,064E-03 0,01796348 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 4,064E-03 0,01792051 ! endothelial cell differentiation GO:0045446 7 7 0,000 4,064E-03 0,01787774 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 4,064E-03 0,01783517 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 4,064E-03 0,01779281 ! digestive system development GO:0055123 7 7 0,000 4,064E-03 0,01775065 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 4,064E-03 0,01770868 ! regulation of exit from mitosis GO:0007096 7 7 0,000 4,064E-03 0,01766692 ! protein targeting to ER GO:0045047 8 7 0,000 4,064E-03 0,01762535 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 4,064E-03 0,01758397 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 4,064E-03 0,01754279 ! endoderm development GO:0007492 7 7 0,000 4,064E-03 0,01750181 ! regulation of defense response to virus GO:0050688 7 7 0,000 4,064E-03 0,01746101 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 4,064E-03 0,0174204 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 4,064E-03 0,01737998 ! response to hexose stimulus GO:0009746 7 7 0,000 4,064E-03 0,01733975 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 4,064E-03 0,01729971 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 4,064E-03 0,01725985 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 4,064E-03 0,01722017 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 4,064E-03 0,01718067 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 4,064E-03 0,01714136 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 4,064E-03 0,01710222 ! complement activation, alternative pathway GO:0006957 7 7 0,000 4,064E-03 0,01706326 ! arachidonic acid secretion GO:0050482 7 7 0,000 4,064E-03 0,01702448 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 4,064E-03 0,01698588 ! response to X-ray GO:0010165 7 7 0,000 4,064E-03 0,01694745 ! regulation of intracellular pH GO:0051453 7 7 0,000 4,064E-03 0,01690919 ! UV protection GO:0009650 7 7 0,000 4,064E-03 0,01687111 ! DNA integration GO:0015074 7 7 0,000 4,064E-03 0,0168332 ! myofibril assembly GO:0030239 7 7 0,000 4,064E-03 0,01679545 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 4,064E-03 0,01675788 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 4,064E-03 0,01672048 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 4,064E-03 0,01668324 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 4,064E-03 0,01664616 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 4,064E-03 0,01660925 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 4,064E-03 0,01657251 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 4,064E-03 0,01653592 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 4,064E-03 0,0164995 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 4,064E-03 0,01646324 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 4,064E-03 0,01642713 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 4,064E-03 0,01639119 ! axon cargo transport GO:0008088 7 7 0,000 4,064E-03 0,0163554 ! eating behavior GO:0042755 7 7 0,000 4,064E-03 0,01631977 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 4,064E-03 0,01628429 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 4,064E-03 0,01624897 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 4,064E-03 0,01621379 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 4,064E-03 0,01617878 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 4,064E-03 0,01614391 ! cranial nerve development GO:0021545 7 7 0,000 4,064E-03 0,01610919 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 4,064E-03 0,01607462 ! induction of an organ GO:0001759 7 7 0,000 4,064E-03 0,0160402 ! leukocyte activation during immune response GO:0002366 7 7 0,000 4,064E-03 0,01600593 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 4,064E-03 0,0159718 ! autonomic nervous system development GO:0048483 7 7 0,000 4,064E-03 0,01593781 ! intracellular lipid transport GO:0032365 7 7 0,000 4,064E-03 0,01590398 ! detection of chemical stimulus GO:0009593 8 7 0,000 4,064E-03 0,01587028 ! platelet activation GO:0030168 8 7 0,000 4,064E-03 0,01583673 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 4,064E-03 0,01580332 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 4,064E-03 0,01577005 ! natural killer cell activation GO:0030101 7 7 0,000 4,064E-03 0,01573692 ! response to gamma radiation GO:0010332 8 7 0,000 4,064E-03 0,01570393 ! NADP metabolic process GO:0006739 7 7 0,000 4,064E-03 0,01567107 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 4,064E-03 0,01563836 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 4,064E-03 0,01560578 ! ubiquinone metabolic process GO:0006743 7 7 0,000 4,064E-03 0,01557333 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 4,064E-03 0,01554102 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 4,064E-03 0,01550885 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 4,064E-03 0,0154768 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 4,064E-03 0,01544489 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 4,064E-03 0,01541311 ! regulation of ATPase activity GO:0043462 7 7 0,000 4,064E-03 0,01538146 ! cell-cell recognition GO:0009988 8 7 0,000 4,064E-03 0,01534994 ! hormone catabolic process GO:0042447 7 7 0,000 4,064E-03 0,01531855 ! dopamine metabolic process GO:0042417 7 7 0,000 4,064E-03 0,01528729 ! cAMP biosynthetic process GO:0006171 7 7 0,000 4,064E-03 0,01525616 ! oxygen transport GO:0015671 7 7 0,000 4,064E-03 0,01522515 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 4,064E-03 0,01519427 ! regulation of mRNA stability GO:0043488 7 7 0,000 4,064E-03 0,01516351 ! biogenic amine catabolic process GO:0042402 7 7 0,000 4,064E-03 0,01513287 ! regulation of axon extension GO:0030516 7 7 0,000 4,064E-03 0,01510236 ! cell killing GO:0001906 7 7 0,000 4,064E-03 0,01507198 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 4,064E-03 0,01504171 ! adult feeding behavior GO:0008343 7 7 0,000 4,064E-03 0,01501157 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 4,064E-03 0,01498155 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 4,064E-03 0,01495164 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 4,064E-03 0,01492186 ! negative regulation of T cell activation GO:0050868 7 7 0,000 4,064E-03 0,01489219 ! response to cold GO:0009409 7 7 0,000 4,064E-03 0,01486264 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 4,644E-03 0,01694855 ! negative regulation of muscle development GO:0048635 8 8 0,000 4,644E-03 0,01691505 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 4,644E-03 0,01688169 ! positive regulation of translation GO:0045727 8 8 0,000 4,644E-03 0,01684846 ! positive regulation of cell killing GO:0031343 8 8 0,000 4,644E-03 0,01681536 ! superoxide anion generation GO:0042554 8 8 0,000 4,644E-03 0,01678238 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 4,644E-03 0,01674954 ! cGMP metabolic process GO:0046068 8 8 0,000 4,644E-03 0,01671683 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 4,644E-03 0,01668424 ! 'de novo' protein folding GO:0006458 8 8 0,000 4,644E-03 0,01665178 ! dicarboxylic acid transport GO:0006835 8 8 0,000 4,644E-03 0,01661945 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 4,644E-03 0,01658724 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 4,644E-03 0,01655516 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 4,644E-03 0,0165232 ! zinc ion transport GO:0006829 8 8 0,000 4,644E-03 0,01649136 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 4,644E-03 0,01645965 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 4,644E-03 0,01642805 ! cardiac muscle contraction GO:0060048 8 8 0,000 4,644E-03 0,01639658 ! lipid localization GO:0010876 8 8 0,000 4,644E-03 0,01636523 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 4,644E-03 0,016334 ! response to cAMP GO:0051591 8 8 0,000 4,644E-03 0,01630289 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 4,644E-03 0,01627189 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 4,644E-03 0,01624102 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 4,644E-03 0,01621026 ! negative regulation of ion transport GO:0043271 8 8 0,000 4,644E-03 0,01617961 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 4,644E-03 0,01614909 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 4,644E-03 0,01611867 ! sensory perception of taste GO:0050909 8 8 0,000 4,644E-03 0,01608838 ! organelle fusion GO:0048284 8 8 0,000 4,644E-03 0,01605819 ! pancreas development GO:0031016 8 8 0,000 4,644E-03 0,01602812 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 4,644E-03 0,01599816 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 4,644E-03 0,01596831 ! negative regulation of proteolysis GO:0045861 8 8 0,000 4,644E-03 0,01593858 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 4,644E-03 0,01590895 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 4,644E-03 0,01587944 ! sperm motility GO:0030317 8 8 0,000 4,644E-03 0,01585003 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 4,644E-03 0,01582073 ! DNA duplex unwinding GO:0032508 8 8 0,000 4,644E-03 0,01579154 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 4,644E-03 0,01576246 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 4,644E-03 0,01573349 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 4,644E-03 0,01570462 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 4,644E-03 0,01567585 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 4,644E-03 0,0156472 ! Golgi organization GO:0007030 8 8 0,000 4,644E-03 0,01561864 ! cell-cell junction assembly GO:0007043 8 8 0,000 4,644E-03 0,01559019 ! regulation of stress fiber formation GO:0051492 9 8 0,000 4,644E-03 0,01556185 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 4,644E-03 0,0155336 ! fructose metabolic process GO:0006000 8 8 0,000 4,644E-03 0,01550546 ! mannose metabolic process GO:0006013 9 8 0,000 4,644E-03 0,01547743 ! NAD metabolic process GO:0019674 8 8 0,000 4,644E-03 0,01544949 ! sex determination GO:0007530 8 8 0,000 4,644E-03 0,01542165 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 4,644E-03 0,01539391 ! plasma membrane fusion GO:0045026 8 8 0,000 4,644E-03 0,01536628 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 4,644E-03 0,01533874 ! response to fungus GO:0009620 8 8 0,000 4,644E-03 0,0153113 ! stem cell differentiation GO:0048863 8 8 0,000 4,644E-03 0,01528396 ! alpha-beta T cell activation GO:0046631 8 8 0,000 4,644E-03 0,01525671 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 4,644E-03 0,01522957 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 4,644E-03 0,01520252 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 4,644E-03 0,01517556 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 4,644E-03 0,0151487 ! regulation of vasodilation GO:0042312 8 8 0,000 4,644E-03 0,01512194 ! vasoconstriction GO:0042310 8 8 0,000 4,644E-03 0,01509527 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 4,644E-03 0,01506869 ! muscle cell development GO:0055001 8 8 0,000 4,644E-03 0,01504221 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 4,644E-03 0,01501582 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 4,644E-03 0,01498952 ! sensory perception of pain GO:0019233 8 8 0,000 4,644E-03 0,01496332 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 4,644E-03 0,0149372 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 4,644E-03 0,01491118 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 4,644E-03 0,01488525 ! chromatin silencing GO:0006342 8 8 0,000 4,644E-03 0,0148594 ! tissue regeneration GO:0042246 8 8 0,000 4,644E-03 0,01483365 ! salivary gland development GO:0007431 8 8 0,000 4,644E-03 0,01480799 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 4,644E-03 0,01478241 ! T cell homeostasis GO:0043029 8 8 0,000 4,644E-03 0,01475692 ! peptide biosynthetic process GO:0043043 9 8 0,000 4,644E-03 0,01473153 ! peptidyl-serine modification GO:0018209 8 8 0,000 4,644E-03 0,01470621 ! water homeostasis GO:0030104 8 8 0,000 4,644E-03 0,01468099 ! cofactor transport GO:0051181 8 8 0,000 4,644E-03 0,01465585 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 4,644E-03 0,0146308 ! acid secretion GO:0046717 8 8 0,000 4,644E-03 0,01460583 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 4,644E-03 0,01458095 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 4,644E-03 0,01455615 ! protein-chromophore linkage GO:0018298 9 8 0,000 4,644E-03 0,01453144 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 4,644E-03 0,01450681 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 4,644E-03 0,01448226 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 4,644E-03 0,0144578 ! regulation of RNA stability GO:0043487 8 8 0,000 4,644E-03 0,01443342 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 4,644E-03 0,01440912 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 4,644E-03 0,0143849 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 4,644E-03 0,01436077 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 4,644E-03 0,01433671 ! regulation of organic acid transport GO:0032890 8 8 0,000 4,644E-03 0,01431274 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 4,644E-03 0,01428884 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 4,644E-03 0,01426503 ! regulation of multi-organism process GO:0043900 8 8 0,000 4,644E-03 0,01424129 ! positive regulation of amine transport GO:0051954 8 8 0,000 4,644E-03 0,01421764 ! developmental induction GO:0031128 8 8 0,000 4,644E-03 0,01419406 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 4,644E-03 0,01417056 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 4,644E-03 0,01414713 ! actin filament polymerization GO:0030041 9 8 0,000 4,644E-03 0,01412379 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 4,644E-03 0,01410052 ! peptide hormone processing GO:0016486 8 8 0,000 4,644E-03 0,01407733 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 4,644E-03 0,01405421 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 4,644E-03 0,01403117 ! lactation GO:0007595 10 9 0,000 5,223E-03 0,0157558 ! embryonic pattern specification GO:0009880 10 9 0,000 5,223E-03 0,01573005 ! positive regulation of cell size GO:0045793 9 9 0,000 5,223E-03 0,01570439 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 5,223E-03 0,01567882 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 5,223E-03 0,01565332 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 5,223E-03 0,01562791 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 5,223E-03 0,01560258 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 5,223E-03 0,01557734 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 5,223E-03 0,01555217 ! viral genome replication GO:0019079 9 9 0,000 5,223E-03 0,01552709 ! phospholipid catabolic process GO:0009395 9 9 0,000 5,223E-03 0,01550208 ! copper ion transport GO:0006825 9 9 0,000 5,223E-03 0,01547716 ! lipid phosphorylation GO:0046834 9 9 0,000 5,223E-03 0,01545232 ! aminoglycan catabolic process GO:0006026 9 9 0,000 5,223E-03 0,01542755 ! Golgi vesicle budding GO:0048194 9 9 0,000 5,223E-03 0,01540287 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 5,223E-03 0,01537826 ! RNA polyadenylation GO:0043631 9 9 0,000 5,223E-03 0,01535374 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 5,223E-03 0,01532929 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 5,223E-03 0,01530492 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 5,223E-03 0,01528062 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 5,223E-03 0,01525641 ! phospholipid efflux GO:0033700 9 9 0,000 5,223E-03 0,01523227 ! response to alkaloid GO:0043279 10 9 0,000 5,223E-03 0,0152082 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 5,223E-03 0,01518422 ! cytokine biosynthetic process GO:0042089 9 9 0,000 5,223E-03 0,0151603 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 5,223E-03 0,01513647 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 5,223E-03 0,01511271 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 5,223E-03 0,01508902 ! response to ethanol GO:0045471 9 9 0,000 5,223E-03 0,0150654 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 5,223E-03 0,01504186 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 5,223E-03 0,0150184 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 5,223E-03 0,01499501 ! methionine metabolic process GO:0006555 9 9 0,000 5,223E-03 0,01497168 ! glutamine metabolic process GO:0006541 9 9 0,000 5,223E-03 0,01494844 ! cerebral cortex development GO:0021987 9 9 0,000 5,223E-03 0,01492526 ! response to osmotic stress GO:0006970 9 9 0,000 5,223E-03 0,01490216 ! pigmentation during development GO:0048066 9 9 0,000 5,223E-03 0,01487912 ! reverse cholesterol transport GO:0043691 9 9 0,000 5,223E-03 0,01485616 ! central nervous system neuron development GO:0021954 10 9 0,000 5,223E-03 0,01483327 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 5,223E-03 0,01481045 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 5,223E-03 0,0147877 ! substrate-bound cell migration GO:0006929 9 9 0,000 5,223E-03 0,01476502 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 5,223E-03 0,01474241 ! negative regulation of caspase activity GO:0043154 9 9 0,000 5,223E-03 0,01471987 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 5,223E-03 0,01469739 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 5,223E-03 0,01467499 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 5,223E-03 0,01465265 ! regulation of dephosphorylation GO:0035303 9 9 0,000 5,223E-03 0,01463039 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 5,223E-03 0,01460818 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 5,223E-03 0,01458605 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 5,223E-03 0,01456398 ! behavioral interaction between organisms GO:0051705 9 9 0,000 5,223E-03 0,01454198 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 5,223E-03 0,01452005 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 5,223E-03 0,01449818 ! DNA replication initiation GO:0006270 9 9 0,000 5,223E-03 0,01447638 ! prostaglandin metabolic process GO:0006693 9 9 0,000 5,223E-03 0,01445464 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 5,223E-03 0,01443297 ! regulation of cellular pH GO:0030641 9 9 0,000 5,223E-03 0,01441137 ! histone acetylation GO:0016573 9 9 0,000 5,223E-03 0,01438983 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 5,223E-03 0,01436835 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 5,223E-03 0,01434693 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 5,223E-03 0,01432559 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 5,223E-03 0,0143043 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 5,223E-03 0,01428308 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 5,223E-03 0,01426192 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 5,223E-03 0,01424082 ! negative regulation of protein secretion GO:0050709 9 9 0,000 5,223E-03 0,01421978 ! regulation of leukocyte migration GO:0002685 9 9 0,000 5,223E-03 0,01419881 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 5,223E-03 0,0141779 ! collagen catabolic process GO:0030574 9 9 0,000 5,223E-03 0,01415705 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 5,223E-03 0,01413626 ! purine base metabolic process GO:0006144 9 9 0,000 5,223E-03 0,01411553 ! gas transport GO:0015669 9 9 0,000 5,223E-03 0,01409487 ! cholesterol efflux GO:0033344 9 9 0,000 5,223E-03 0,01407426 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 5,223E-03 0,01405371 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 5,223E-03 0,01403323 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 5,223E-03 0,0140128 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 5,223E-03 0,01399243 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 5,223E-03 0,01397212 ! defense response to virus GO:0051607 9 9 0,000 5,223E-03 0,01395187 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 5,223E-03 0,01393168 ! actin filament-based movement GO:0030048 9 9 0,000 5,223E-03 0,01391155 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 5,223E-03 0,01389148 ! protein import into nucleus, docking GO:0000059 10 10 0,000 5,803E-03 0,01540937 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 5,803E-03 0,0153872 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 5,803E-03 0,01536509 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 5,803E-03 0,01534305 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 5,803E-03 0,01532107 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 5,803E-03 0,01529915 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 5,803E-03 0,01527729 ! neuron maturation GO:0042551 10 10 0,000 5,803E-03 0,0152555 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 5,803E-03 0,01523377 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 5,803E-03 0,0152121 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 5,803E-03 0,01519049 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 5,803E-03 0,01516894 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 5,803E-03 0,01514746 ! hormone secretion GO:0046879 10 10 0,000 5,803E-03 0,01512603 ! glucosamine metabolic process GO:0006041 10 10 0,000 5,803E-03 0,01510467 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 5,803E-03 0,01508336 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 5,803E-03 0,01506212 ! inositol metabolic process GO:0006020 10 10 0,000 5,803E-03 0,01504093 ! cAMP metabolic process GO:0046058 10 10 0,000 5,803E-03 0,01501981 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 5,803E-03 0,01499874 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 5,803E-03 0,01497774 ! glial cell development GO:0021782 10 10 0,000 5,803E-03 0,01495679 ! phototransduction GO:0007602 11 10 0,000 5,803E-03 0,0149359 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 5,803E-03 0,01491507 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 5,803E-03 0,0148943 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 5,803E-03 0,01487358 ! fat cell differentiation GO:0045444 10 10 0,000 5,803E-03 0,01485292 ! myoblast differentiation GO:0045445 10 10 0,000 5,803E-03 0,01483232 ! centrosome cycle GO:0007098 10 10 0,000 5,803E-03 0,01481178 ! inactivation of MAPK activity GO:0000188 10 10 0,000 5,803E-03 0,01479129 ! positive regulation of proteolysis GO:0045862 10 10 0,000 5,803E-03 0,01477086 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 5,803E-03 0,01475049 ! regulation of survival gene product expression GO:0045884 10 10 0,000 5,803E-03 0,01473017 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 5,803E-03 0,01470991 ! epidermis morphogenesis GO:0048730 10 10 0,000 5,803E-03 0,0146897 ! protein polyubiquitination GO:0000209 10 10 0,000 5,803E-03 0,01466955 ! glutamate metabolic process GO:0006536 11 10 0,000 5,803E-03 0,01464946 ! plasma membrane organization GO:0007009 10 10 0,000 5,803E-03 0,01462942 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 5,803E-03 0,01460943 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 5,803E-03 0,0145895 ! lysosomal transport GO:0007041 10 10 0,000 5,803E-03 0,01456962 ! cellular response to unfolded protein GO:0034620 10 10 0,000 5,803E-03 0,0145498 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 5,803E-03 0,01453003 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 5,803E-03 0,01451032 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 5,803E-03 0,01449066 ! exocrine system development GO:0035272 10 10 0,000 5,803E-03 0,01447105 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 5,803E-03 0,01445149 ! neuromuscular junction development GO:0007528 10 10 0,000 5,803E-03 0,01443199 ! embryo implantation GO:0007566 11 10 0,000 5,803E-03 0,01441254 ! regulation of protein binding GO:0043393 11 10 0,000 5,803E-03 0,01439314 ! protein targeting to peroxisome GO:0006625 10 10 0,000 5,803E-03 0,0143738 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 5,803E-03 0,0143545 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 5,803E-03 0,01433526 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 5,803E-03 0,01431607 ! protein export from nucleus GO:0006611 10 10 0,000 5,803E-03 0,01429693 ! negative regulation of immune response GO:0050777 10 10 0,000 5,803E-03 0,01427784 ! cytolysis GO:0019835 10 10 0,000 5,803E-03 0,01425881 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 5,803E-03 0,01423982 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 5,803E-03 0,01422088 ! regulation of B cell differentiation GO:0045577 10 10 0,000 5,803E-03 0,014202 ! histone deacetylation GO:0016575 10 10 0,000 5,803E-03 0,01418316 ! mRNA splice site selection GO:0006376 11 10 0,000 5,803E-03 0,01416438 ! synaptic vesicle transport GO:0048489 11 10 0,000 5,803E-03 0,01414564 ! gland morphogenesis GO:0022612 10 10 0,000 5,803E-03 0,01412695 ! positive regulation of neurological system process GO:0031646 10 10 0,000 5,803E-03 0,01410832 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 5,803E-03 0,01408973 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 5,803E-03 0,01407119 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 5,803E-03 0,0140527 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 5,803E-03 0,01403426 ! regulation of epidermis development GO:0045682 10 10 0,000 5,803E-03 0,01401586 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 5,803E-03 0,01399752 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 5,803E-03 0,01397922 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 5,803E-03 0,01396097 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 5,803E-03 0,01394277 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 5,803E-03 0,01392461 ! lymphocyte homeostasis GO:0002260 10 10 0,000 5,803E-03 0,01390651 ! nerve development GO:0021675 10 10 0,000 5,803E-03 0,01388845 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 5,803E-03 0,01387043 ! gut development GO:0048565 10 10 0,000 5,803E-03 0,01385247 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 5,803E-03 0,01383455 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 5,803E-03 0,01381667 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 5,803E-03 0,01379884 ! mRNA 3'-end processing GO:0031124 10 10 0,000 5,803E-03 0,01378106 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 5,803E-03 0,01376333 ! negative regulation of coagulation GO:0050819 11 10 0,000 5,803E-03 0,01374564 ! protein stabilization GO:0050821 10 10 0,000 5,803E-03 0,01372799 ! protein secretion GO:0009306 11 11 0,000 6,381E-03 0,01507814 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 6,381E-03 0,01505883 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 6,381E-03 0,01503958 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 6,381E-03 0,01502037 ! negative regulation of defense response GO:0031348 11 11 0,000 6,381E-03 0,01500121 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 6,381E-03 0,0149821 ! determination of bilateral symmetry GO:0009855 11 11 0,000 6,381E-03 0,01496304 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 6,381E-03 0,01494403 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 6,381E-03 0,01492506 ! skin development GO:0043588 11 11 0,000 6,381E-03 0,01490615 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 6,381E-03 0,01488728 ! signal complex assembly GO:0007172 11 11 0,000 6,381E-03 0,01486846 ! microtubule-based transport GO:0010970 11 11 0,000 6,381E-03 0,01484968 ! endothelial cell migration GO:0043542 11 11 0,000 6,381E-03 0,01483096 ! peroxisomal transport GO:0043574 11 11 0,000 6,381E-03 0,01481228 ! protein amino acid methylation GO:0006479 11 11 0,000 6,381E-03 0,01479365 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 6,381E-03 0,01477506 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 6,381E-03 0,01475652 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 6,381E-03 0,01473803 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 6,381E-03 0,01471959 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 6,381E-03 0,01470119 ! T cell proliferation GO:0042098 11 11 0,000 6,381E-03 0,01468283 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 6,381E-03 0,01466452 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 6,381E-03 0,01464626 ! regulation of viral genome replication GO:0045069 11 11 0,000 6,381E-03 0,01462805 ! spinal cord development GO:0021510 11 11 0,000 6,381E-03 0,01460987 ! activation of MAPKK activity GO:0000186 12 11 0,000 6,381E-03 0,01459175 ! smooth muscle contraction GO:0006939 11 11 0,000 6,381E-03 0,01457367 ! cellular response to starvation GO:0009267 11 11 0,000 6,381E-03 0,01455563 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 6,381E-03 0,01453764 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 6,381E-03 0,01451969 ! digestive system process GO:0022600 11 11 0,000 6,381E-03 0,01450179 ! mitotic spindle organization GO:0007052 11 11 0,000 6,381E-03 0,01448393 ! fucose metabolic process GO:0006004 11 11 0,000 6,381E-03 0,01446611 ! membrane budding GO:0006900 11 11 0,000 6,381E-03 0,01444834 ! apoptotic nuclear changes GO:0030262 11 11 0,000 6,381E-03 0,01443061 ! monoamine transport GO:0015844 11 11 0,000 6,381E-03 0,01441293 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 6,381E-03 0,01439529 ! response to lipopolysaccharide GO:0032496 11 11 0,000 6,381E-03 0,01437769 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 6,381E-03 0,01436013 ! body fluid secretion GO:0007589 11 11 0,000 6,381E-03 0,01434262 ! G1/S transition checkpoint GO:0031575 12 11 0,000 6,381E-03 0,01432515 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 6,381E-03 0,01430772 ! intermediate filament-based process GO:0045103 11 11 0,000 6,381E-03 0,01429034 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 6,381E-03 0,014273 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 6,381E-03 0,0142557 ! membrane depolarization GO:0051899 11 11 0,000 6,381E-03 0,01423844 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 6,381E-03 0,01422122 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 6,381E-03 0,01420404 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 6,381E-03 0,01418691 ! oogenesis GO:0048477 11 11 0,000 6,381E-03 0,01416982 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 6,381E-03 0,01415277 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 6,381E-03 0,01413576 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 6,381E-03 0,01411879 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 6,381E-03 0,01410186 ! muscle maintenance GO:0046716 12 11 0,000 6,381E-03 0,01408497 ! vitamin A metabolic process GO:0006776 11 11 0,000 6,381E-03 0,01406812 ! steroid catabolic process GO:0006706 11 11 0,000 6,381E-03 0,01405131 ! endocrine process GO:0050886 11 11 0,000 6,381E-03 0,01403455 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 6,381E-03 0,01401782 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 6,381E-03 0,01400113 ! RNA 3'-end processing GO:0031123 11 11 0,000 6,381E-03 0,01398448 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 6,381E-03 0,01396787 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 6,96E-03 0,01521628 ! translational initiation GO:0006413 12 12 0,000 6,96E-03 0,01519826 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 6,96E-03 0,01518027 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 6,96E-03 0,01516233 ! initiation of viral infection GO:0019059 12 12 0,000 6,96E-03 0,01514442 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 6,96E-03 0,01512657 ! iron ion transport GO:0006826 13 12 0,000 6,96E-03 0,01510875 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 6,96E-03 0,01509097 ! amino sugar metabolic process GO:0006040 12 12 0,000 6,96E-03 0,01507324 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 6,96E-03 0,01505555 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 6,96E-03 0,0150379 ! heterophilic cell adhesion GO:0007157 12 12 0,000 6,96E-03 0,01502029 ! collagen metabolic process GO:0032963 12 12 0,000 6,96E-03 0,01500272 ! hindlimb morphogenesis GO:0035137 12 12 0,000 6,96E-03 0,0149852 ! xenobiotic metabolic process GO:0006805 12 12 0,000 6,96E-03 0,01496771 ! glutamate signaling pathway GO:0007215 12 12 0,000 6,96E-03 0,01495027 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 6,96E-03 0,01493286 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 6,96E-03 0,0149155 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 6,96E-03 0,01489817 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 6,96E-03 0,01488089 ! actomyosin structure organization GO:0031032 12 12 0,000 6,96E-03 0,01486365 ! microtubule organizing center organization GO:0031023 12 12 0,000 6,96E-03 0,01484644 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 6,96E-03 0,01482928 ! retinoid metabolic process GO:0001523 12 12 0,000 6,96E-03 0,01481216 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 6,96E-03 0,01479507 ! positive regulation of innate immune response GO:0045089 12 12 0,000 6,96E-03 0,01477803 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 6,96E-03 0,01476102 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 6,96E-03 0,01474405 ! acute-phase response GO:0006953 12 12 0,000 6,96E-03 0,01472713 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 6,96E-03 0,01471024 ! vacuolar transport GO:0007034 12 12 0,000 6,96E-03 0,01469339 ! polysaccharide catabolic process GO:0000272 12 12 0,000 6,96E-03 0,01467658 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 6,96E-03 0,0146598 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 6,96E-03 0,01464307 ! barbed-end actin filament capping GO:0051016 12 12 0,000 6,96E-03 0,01462637 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 6,96E-03 0,01460971 ! male gonad development GO:0008584 12 12 0,000 6,96E-03 0,01459309 ! regulation of insulin secretion GO:0050796 12 12 0,000 6,96E-03 0,01457651 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 6,96E-03 0,01455996 ! renal system process GO:0003014 12 12 0,000 6,96E-03 0,01454346 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 6,96E-03 0,01452699 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 6,96E-03 0,01451055 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 6,96E-03 0,01449416 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 6,96E-03 0,0144778 ! pallium development GO:0021543 13 12 0,000 6,96E-03 0,01446147 ! cell fate determination GO:0001709 12 12 0,000 6,96E-03 0,01444519 ! regulation of chromosome organization GO:0033044 12 12 0,000 6,96E-03 0,01442894 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 6,96E-03 0,01441273 ! somitogenesis GO:0001756 13 12 0,000 6,96E-03 0,01439655 ! G1 phase GO:0051318 13 12 0,000 6,96E-03 0,01438041 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 6,96E-03 0,01436431 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 6,96E-03 0,01434824 ! detection of light stimulus GO:0009583 13 12 0,000 6,96E-03 0,01433221 ! synaptogenesis GO:0007416 12 12 0,000 6,96E-03 0,01431621 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 6,96E-03 0,01430025 ! hormone transport GO:0009914 12 12 0,000 6,96E-03 0,01428433 ! neurotransmitter secretion GO:0007269 14 12 0,000 6,96E-03 0,01426844 ! heme biosynthetic process GO:0006783 12 12 0,000 6,96E-03 0,01425259 ! spermatid differentiation GO:0048515 13 12 0,000 6,96E-03 0,01423677 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 6,96E-03 0,01422098 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 6,96E-03 0,01420524 ! neural tube closure GO:0001843 13 12 0,000 6,96E-03 0,01418952 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 6,96E-03 0,01417384 ! negative regulation of translation GO:0017148 12 12 0,000 6,96E-03 0,0141582 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 6,96E-03 0,01414259 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 6,96E-03 0,01412701 ! positive regulation of DNA replication GO:0045740 14 13 0,000 7,538E-03 0,01528409 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 7,538E-03 0,0152673 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 7,538E-03 0,01525054 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 7,538E-03 0,01523382 ! phenol metabolic process GO:0018958 13 13 0,000 7,538E-03 0,01521713 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 7,538E-03 0,01520048 ! gluconeogenesis GO:0006094 13 13 0,000 7,538E-03 0,01518387 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 7,538E-03 0,01516729 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 7,538E-03 0,01515075 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 7,538E-03 0,01513425 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 7,538E-03 0,01511778 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 7,538E-03 0,01510135 ! regeneration GO:0031099 13 13 0,000 7,538E-03 0,01508495 ! keratinization GO:0031424 13 13 0,000 7,538E-03 0,01506859 ! post-embryonic development GO:0009791 14 13 0,000 7,538E-03 0,01505227 ! negative regulation of protein modification process GO:0031400 13 13 0,000 7,538E-03 0,01503597 ! patterning of blood vessels GO:0001569 13 13 0,000 7,538E-03 0,01501972 ! vasculogenesis GO:0001570 13 13 0,000 7,538E-03 0,0150035 ! regulation of DNA recombination GO:0000018 13 13 0,000 7,538E-03 0,01498731 ! regulation of innate immune response GO:0045088 13 13 0,000 7,538E-03 0,01497116 ! mitochondrial membrane organization GO:0007006 13 13 0,000 7,538E-03 0,01495505 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 7,538E-03 0,01493897 ! negative regulation of DNA replication GO:0008156 13 13 0,000 7,538E-03 0,01492292 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 7,538E-03 0,01490691 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 7,538E-03 0,01489093 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 7,538E-03 0,01487499 ! autophagy GO:0006914 13 13 0,000 7,538E-03 0,01485908 ! receptor metabolic process GO:0043112 14 13 0,000 7,538E-03 0,01484321 ! actin filament bundle formation GO:0051017 13 13 0,000 7,538E-03 0,01482736 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 7,538E-03 0,01481156 ! ureteric bud development GO:0001657 13 13 0,000 7,538E-03 0,01479578 ! cell aging GO:0007569 13 13 0,000 7,538E-03 0,01478004 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 7,538E-03 0,01476434 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 7,538E-03 0,01474866 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 7,538E-03 0,01473302 ! coenzyme catabolic process GO:0009109 13 13 0,000 7,538E-03 0,01471742 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 7,538E-03 0,01470184 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 7,538E-03 0,0146863 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 7,538E-03 0,01467079 ! regulation of viral reproduction GO:0050792 13 13 0,000 7,538E-03 0,01465532 ! nucleobase metabolic process GO:0009112 13 13 0,000 7,538E-03 0,01463987 ! regulation of axonogenesis GO:0050770 14 13 0,000 7,538E-03 0,01462446 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 7,538E-03 0,01460909 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 7,538E-03 0,01459374 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 7,538E-03 0,01457843 ! vasodilation GO:0042311 14 13 0,000 7,538E-03 0,01456315 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 7,538E-03 0,0145479 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 7,538E-03 0,01453268 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 7,538E-03 0,01451749 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 7,538E-03 0,01450234 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 7,538E-03 0,01448722 ! neutrophil chemotaxis GO:0030593 14 13 0,000 7,538E-03 0,01447213 ! long-chain fatty acid transport GO:0015909 13 13 0,000 7,538E-03 0,01445707 ! immunoglobulin production GO:0002377 13 13 0,000 7,538E-03 0,01444204 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 7,538E-03 0,01442704 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 7,538E-03 0,01441208 ! cell-cell junction organization GO:0045216 13 13 0,000 7,538E-03 0,01439714 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 7,538E-03 0,01438224 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 7,538E-03 0,01436736 ! response to cytokine stimulus GO:0034097 13 13 0,000 7,538E-03 0,01435252 ! activation of JUN kinase activity GO:0007257 13 13 0,000 7,538E-03 0,01433771 ! terpenoid metabolic process GO:0006721 13 13 0,000 7,538E-03 0,01432293 ! alkene biosynthetic process GO:0043450 13 13 0,000 7,538E-03 0,01430818 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 7,538E-03 0,01429346 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 7,538E-03 0,01427877 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 7,538E-03 0,01426411 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 7,538E-03 0,01424948 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 7,538E-03 0,01423488 ! blastocyst development GO:0001824 13 13 0,000 7,538E-03 0,01422031 ! telomere organization GO:0032200 13 13 0,000 7,538E-03 0,01420577 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 7,538E-03 0,01419126 ! regulation of amine transport GO:0051952 13 13 0,000 7,538E-03 0,01417678 ! tissue homeostasis GO:0001894 13 13 0,000 7,538E-03 0,01416233 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 7,538E-03 0,0141479 ! protein tetramerization GO:0051262 13 13 0,000 7,538E-03 0,01413351 ! neuron fate commitment GO:0048663 14 14 0,000 8,116E-03 0,01520192 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 8,116E-03 0,01518649 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 8,116E-03 0,01517108 ! pyruvate metabolic process GO:0006090 14 14 0,000 8,116E-03 0,01515571 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 8,116E-03 0,01514037 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 8,116E-03 0,01512506 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 8,116E-03 0,01510979 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 8,116E-03 0,01509454 ! protein amino acid acylation GO:0043543 14 14 0,000 8,116E-03 0,01507932 ! regulation of neuron projection development GO:0010975 15 14 0,000 8,116E-03 0,01506414 ! protein amino acid deacetylation GO:0006476 14 14 0,000 8,116E-03 0,01504898 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 8,116E-03 0,01503386 ! vesicle docking GO:0048278 14 14 0,000 8,116E-03 0,01501876 ! superoxide metabolic process GO:0006801 15 14 0,000 8,116E-03 0,0150037 ! macromolecular complex disassembly GO:0032984 15 14 0,000 8,116E-03 0,01498867 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 8,116E-03 0,01497366 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 8,116E-03 0,01495869 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 8,116E-03 0,01494374 ! hair cycle GO:0042633 14 14 0,000 8,116E-03 0,01492883 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 8,116E-03 0,01491395 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 8,116E-03 0,01489909 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 8,116E-03 0,01488427 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 8,116E-03 0,01486947 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 8,116E-03 0,01485471 ! lysosome organization GO:0007040 14 14 0,000 8,116E-03 0,01483997 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 8,116E-03 0,01482526 ! D-ribose metabolic process GO:0006014 14 14 0,000 8,116E-03 0,01481058 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 8,116E-03 0,01479593 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 8,116E-03 0,01478131 ! primary neural tube formation GO:0014020 15 14 0,000 8,116E-03 0,01476672 ! peptide cross-linking GO:0018149 14 14 0,000 8,116E-03 0,01475216 ! regulation of behavior GO:0050795 14 14 0,000 8,116E-03 0,01473762 ! vitamin biosynthetic process GO:0009110 14 14 0,000 8,116E-03 0,01472312 ! base-excision repair GO:0006284 14 14 0,000 8,116E-03 0,01470864 ! response to organic cyclic substance GO:0014070 15 14 0,000 8,116E-03 0,01469419 ! leukotriene metabolic process GO:0006691 14 14 0,000 8,116E-03 0,01467977 ! regulation of vasoconstriction GO:0019229 14 14 0,000 8,116E-03 0,01466538 ! formation of primary germ layer GO:0001704 14 14 0,000 8,116E-03 0,01465102 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 8,116E-03 0,01463668 ! collagen fibril organization GO:0030199 14 14 0,000 8,116E-03 0,01462237 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 8,116E-03 0,01460809 ! regulation of blood coagulation GO:0030193 15 14 0,000 8,116E-03 0,01459384 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 8,116E-03 0,01457962 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 8,116E-03 0,01456542 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 8,116E-03 0,01455125 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 8,116E-03 0,01453711 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 8,116E-03 0,014523 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 8,116E-03 0,01450891 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 8,116E-03 0,01449485 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 8,694E-03 0,01551178 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 8,694E-03 0,01549678 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 8,694E-03 0,01548181 ! positive regulation of ossification GO:0045778 15 15 0,000 8,694E-03 0,01546686 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 8,694E-03 0,01545195 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 8,694E-03 0,01543706 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 8,694E-03 0,0154222 ! proteoglycan metabolic process GO:0006029 15 15 0,000 8,694E-03 0,01540738 ! response to vitamin GO:0033273 15 15 0,000 8,694E-03 0,01539257 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 8,694E-03 0,0153778 ! striated muscle cell differentiation GO:0051146 16 15 0,000 8,694E-03 0,01536306 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 8,694E-03 0,01534834 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 8,694E-03 0,01533366 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 8,694E-03 0,015319 ! ovarian follicle development GO:0001541 15 15 0,000 8,694E-03 0,01530436 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 8,694E-03 0,01528976 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 8,694E-03 0,01527519 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 8,694E-03 0,01526064 ! complement activation, classical pathway GO:0006958 15 15 0,000 8,694E-03 0,01524612 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 8,694E-03 0,01523163 ! heme metabolic process GO:0042168 15 15 0,000 8,694E-03 0,01521716 ! mesoderm morphogenesis GO:0048332 15 15 0,000 8,694E-03 0,01520272 ! chromosome condensation GO:0030261 15 15 0,000 8,694E-03 0,01518831 ! response to starvation GO:0042594 15 15 0,000 8,694E-03 0,01517393 ! response to ionizing radiation GO:0010212 16 15 0,000 8,694E-03 0,01515957 ! response to mechanical stimulus GO:0009612 15 15 0,000 8,694E-03 0,01514525 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 8,694E-03 0,01513094 ! regulation of biomineral formation GO:0070167 15 15 0,000 8,694E-03 0,01511667 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 8,694E-03 0,01510242 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 8,694E-03 0,0150882 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 8,694E-03 0,01507401 ! phospholipid transport GO:0015914 15 15 0,000 8,694E-03 0,01505984 ! leukocyte homeostasis GO:0001776 15 15 0,000 8,694E-03 0,0150457 ! regulation of cytokine secretion GO:0050707 15 15 0,000 8,694E-03 0,01503159 ! glutathione metabolic process GO:0006749 16 15 0,000 8,694E-03 0,0150175 ! nicotinamide metabolic process GO:0006769 15 15 0,000 8,694E-03 0,01500344 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 8,694E-03 0,0149894 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 8,694E-03 0,01497539 ! cellular alkene metabolic process GO:0043449 15 15 0,000 8,694E-03 0,01496141 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 8,694E-03 0,01494745 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 8,694E-03 0,01493352 ! negative regulation of cell activation GO:0050866 15 15 0,000 8,694E-03 0,01491962 ! protein homooligomerization GO:0051260 15 15 0,000 8,694E-03 0,01490574 ! positive regulation of immune effector process GO:0002699 15 15 0,000 8,694E-03 0,01489189 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 9,272E-03 0,01586647 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 9,272E-03 0,01585175 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 9,272E-03 0,01583706 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 9,272E-03 0,01582239 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 9,272E-03 0,01580776 ! learning GO:0007612 16 16 0,000 9,272E-03 0,01579315 ! circadian rhythm GO:0007623 16 16 0,000 9,272E-03 0,01577857 ! inner ear morphogenesis GO:0042472 16 16 0,000 9,272E-03 0,01576401 ! positive regulation of mitosis GO:0045840 16 16 0,000 9,272E-03 0,01574948 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 9,272E-03 0,01573498 ! vacuole organization GO:0007033 16 16 0,000 9,272E-03 0,0157205 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 9,272E-03 0,01570605 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 9,272E-03 0,01569163 ! vesicle targeting GO:0006903 17 16 0,000 9,272E-03 0,01567724 ! segmentation GO:0035282 17 16 0,000 9,272E-03 0,01566287 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 9,272E-03 0,01564852 ! triglyceride metabolic process GO:0006641 16 16 0,000 9,272E-03 0,01563421 ! iron ion homeostasis GO:0055072 16 16 0,000 9,272E-03 0,01561991 ! positive regulation of cell development GO:0010720 16 16 0,000 9,272E-03 0,01560565 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 9,272E-03 0,01559141 ! lymphocyte proliferation GO:0046651 16 16 0,000 9,272E-03 0,0155772 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 9,272E-03 0,01556301 ! cell fate specification GO:0001708 16 16 0,000 9,272E-03 0,01554885 ! pentose metabolic process GO:0019321 16 16 0,000 9,272E-03 0,01553471 ! fatty acid transport GO:0015908 16 16 0,000 9,272E-03 0,01552061 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 9,272E-03 0,01550652 ! cellular response to nutrient levels GO:0031669 16 16 0,000 9,272E-03 0,01549246 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 9,272E-03 0,01547843 ! cofactor catabolic process GO:0051187 16 16 0,000 9,272E-03 0,01546442 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 9,272E-03 0,01545044 ! polyol metabolic process GO:0019751 16 16 0,000 9,272E-03 0,01543648 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 9,272E-03 0,01542255 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 9,272E-03 0,01540864 ! porphyrin metabolic process GO:0006778 16 16 0,000 9,272E-03 0,01539476 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 9,272E-03 0,01538091 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 9,272E-03 0,01536707 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 9,272E-03 0,01535327 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 9,272E-03 0,01533949 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 9,272E-03 0,01532573 ! regulation of coagulation GO:0050818 17 16 0,000 9,272E-03 0,015312 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 9,849E-03 0,01625088 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 9,849E-03 0,01623635 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 9,849E-03 0,01622184 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 9,849E-03 0,01620736 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 9,849E-03 0,0161929 ! myelination GO:0042552 17 17 0,000 9,849E-03 0,01617846 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 9,849E-03 0,01616406 ! regulation of transmembrane transport GO:0034762 17 17 0,000 9,849E-03 0,01614968 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 9,849E-03 0,01613532 ! leukocyte adhesion GO:0007159 17 17 0,000 9,849E-03 0,01612099 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 9,849E-03 0,01610669 ! sensory perception of smell GO:0007608 17 17 0,000 9,849E-03 0,01609241 ! glucose transport GO:0015758 17 17 0,000 9,849E-03 0,01607816 ! cell junction assembly GO:0034329 18 17 0,000 9,849E-03 0,01606393 ! tissue remodeling GO:0048771 17 17 0,000 9,849E-03 0,01604972 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 9,849E-03 0,01603555 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 9,849E-03 0,01602139 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 9,849E-03 0,01600726 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 9,849E-03 0,01599316 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 9,849E-03 0,01597908 ! neural crest cell development GO:0014032 19 17 0,000 9,849E-03 0,01596503 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 9,849E-03 0,015951 ! negative regulation of cell development GO:0010721 18 17 0,000 9,849E-03 0,015937 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 9,849E-03 0,01592302 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 9,849E-03 0,01590906 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 9,849E-03 0,01589513 ! positive regulation of protein secretion GO:0050714 17 17 0,000 9,849E-03 0,01588122 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 9,849E-03 0,01586734 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 9,849E-03 0,01585348 ! myeloid leukocyte activation GO:0002274 18 17 0,000 9,849E-03 0,01583965 ! adult locomotory behavior GO:0008344 17 17 0,000 9,849E-03 0,01582584 ! embryonic organ development GO:0048568 17 17 0,000 9,849E-03 0,01581205 ! regulation of calcium ion transport GO:0051924 17 17 0,000 9,849E-03 0,01579829 ! liver development GO:0001889 17 17 0,000 9,849E-03 0,01578455 ! gene silencing GO:0016458 17 17 0,000 9,849E-03 0,01577084 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,01042638 0,0166804 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,01042638 0,01666594 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,01042638 0,01665149 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,01042638 0,01663708 ! meiosis I GO:0007127 18 18 0,000 0,01042638 0,01662268 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,01042638 0,01660832 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,01042638 0,01659398 ! membrane docking GO:0022406 18 18 0,000 0,01042638 0,01657966 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,01042638 0,01656537 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,01042638 0,0165511 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,01042638 0,01653685 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,01042638 0,01652263 ! hexose transport GO:0008645 18 18 0,000 0,01042638 0,01650844 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,01042638 0,01649427 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,01042638 0,01648012 ! striated muscle contraction GO:0006941 18 18 0,000 0,01042638 0,016466 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,01042638 0,0164519 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,01042638 0,01643783 ! ceramide metabolic process GO:0006672 18 18 0,000 0,01042638 0,01642378 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,01042638 0,01640976 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,01042638 0,01639575 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,01042638 0,01638178 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,01042638 0,01636782 ! B cell differentiation GO:0030183 18 18 0,000 0,01042638 0,01635389 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,01042638 0,01633999 ! ensheathment of neurons GO:0007272 18 18 0,000 0,01042638 0,0163261 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,01042638 0,01631224 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,01042638 0,01629841 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,01042638 0,0162846 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,01042638 0,01627081 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,01042638 0,01625704 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01100323 0,01714197 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01100323 0,01712749 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01100323 0,01711303 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01100323 0,0170986 ! glial cell differentiation GO:0010001 19 19 0,000 0,01100323 0,0170842 ! regulation of pH GO:0006885 19 19 0,000 0,01100323 0,01706982 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01100323 0,01705546 ! feeding behavior GO:0007631 19 19 0,000 0,01100323 0,01704113 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01100323 0,01702682 ! peroxisome organization GO:0007031 19 19 0,000 0,01100323 0,01701254 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01100323 0,01699828 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01100323 0,01698404 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01100323 0,01696983 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01100323 0,01695564 ! metanephros development GO:0001656 19 19 0,000 0,01100323 0,01694147 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01100323 0,01692733 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01100323 0,01691321 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01100323 0,01689912 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01100323 0,01688505 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01100323 0,016871 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01100323 0,01685698 ! regulation of protein stability GO:0031647 19 19 0,000 0,01100323 0,01684298 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01100323 0,016829 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01100323 0,01681505 ! eye morphogenesis GO:0048592 19 19 0,000 0,01100323 0,01680111 ! regulation of cell shape GO:0008360 21 19 0,000 0,01100323 0,01678721 ! placenta development GO:0001890 19 19 0,000 0,01100323 0,01677332 ! response to heat GO:0009408 19 19 0,000 0,01100323 0,01675946 ! vesicle localization GO:0051648 20 19 0,000 0,01100323 0,01674562 ! regulation of muscle development GO:0048634 21 20 0,000 0,01157982 0,01760858 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,01157982 0,01759407 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,01157982 0,01757957 ! negative regulation of binding GO:0051100 21 20 0,000 0,01157982 0,0175651 ! organic ether metabolic process GO:0018904 20 20 0,000 0,01157982 0,01755066 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,01157982 0,01753624 ! nucleus organization GO:0006997 20 20 0,000 0,01157982 0,01752184 ! phagocytosis GO:0006909 21 20 0,000 0,01157982 0,01750747 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,01157982 0,01749312 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,01157982 0,01747879 ! protein targeting to membrane GO:0006612 22 20 0,000 0,01157982 0,01746449 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,01157982 0,01745021 ! chromatin remodeling GO:0006338 20 20 0,000 0,01157982 0,01743595 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,01157982 0,01742172 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,01157982 0,0174075 ! lipid oxidation GO:0034440 20 20 0,000 0,01157982 0,01739332 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,01157982 0,01737915 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,01157982 0,01736501 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,01157982 0,0173509 ! RNA modification GO:0009451 20 20 0,000 0,01157982 0,0173368 ! single fertilization GO:0007338 21 20 0,000 0,01157982 0,01732273 ! regulation of B cell activation GO:0050864 20 20 0,000 0,01157982 0,01730868 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,01215615 0,01815542 ! mRNA catabolic process GO:0006402 21 21 0,000 0,01215615 0,01814072 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,01215615 0,01812605 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,01215615 0,01811139 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,01215615 0,01809676 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,01215615 0,01808216 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,01215615 0,01806757 ! Notch signaling pathway GO:0007219 22 21 0,000 0,01215615 0,01805302 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,01215615 0,01803848 ! ear morphogenesis GO:0042471 21 21 0,000 0,01215615 0,01802397 ! organic anion transport GO:0015711 21 21 0,000 0,01215615 0,01800948 ! cholesterol transport GO:0030301 21 21 0,000 0,01215615 0,01799501 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,01215615 0,01798057 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,01215615 0,01796615 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,01215615 0,01795176 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,01215615 0,01793738 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,01215615 0,01792303 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,01215615 0,01790871 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,01215615 0,0178944 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,01215615 0,01788012 ! regulation of proteolysis GO:0030162 21 21 0,000 0,01215615 0,01786586 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,01215615 0,01785163 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,01215615 0,01783741 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,01215615 0,01782322 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,01215615 0,01780906 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,01273224 0,01863822 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,01273224 0,01862343 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,01273224 0,01860866 ! sister chromatid segregation GO:0000819 22 22 0,000 0,01273224 0,01859391 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,01273224 0,01857919 ! regulation of ion transport GO:0043269 22 22 0,000 0,01273224 0,01856449 ! odontogenesis GO:0042476 22 22 0,000 0,01273224 0,01854982 ! cell junction organization GO:0034330 23 22 0,000 0,01273224 0,01853517 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,01273224 0,01852054 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,01273224 0,01850593 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,01273224 0,01849135 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,01273224 0,01847679 ! ovulation cycle process GO:0022602 22 22 0,000 0,01273224 0,01846225 ! spindle organization GO:0007051 22 22 0,000 0,01273224 0,01844774 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,01273224 0,01843324 ! cell chemotaxis GO:0060326 23 22 0,000 0,01273224 0,01841878 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,01273224 0,01840433 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,01273224 0,01838991 ! male sex differentiation GO:0046661 22 22 0,000 0,01273224 0,0183755 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,01273224 0,01836113 ! biopolymer methylation GO:0043414 22 22 0,000 0,01273224 0,01834677 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,01273224 0,01833244 ! detection of external stimulus GO:0009581 23 22 0,000 0,01273224 0,01831813 ! neuron migration GO:0001764 22 22 0,000 0,01273224 0,01830384 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,01273224 0,01828957 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,01273224 0,01827533 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,01273224 0,0182611 ! aerobic respiration GO:0009060 22 22 0,000 0,01273224 0,0182469 ! cytokine production GO:0001816 22 22 0,000 0,01273224 0,01823273 ! cytokinesis GO:0000910 23 22 0,000 0,01273224 0,01821857 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,01273224 0,01820444 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,01330807 0,01901301 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,01330807 0,01899828 ! viral infectious cycle GO:0019058 23 23 0,000 0,01330807 0,01898358 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,01330807 0,0189689 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,01330807 0,01895424 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,01330807 0,0189396 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,01330807 0,01892499 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,01330807 0,01891039 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,01330807 0,01889583 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,01330807 0,01888128 ! endocrine system development GO:0035270 23 23 0,000 0,01330807 0,01886676 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,01330807 0,01885225 ! positive regulation of growth GO:0045927 23 23 0,000 0,01330807 0,01883777 ! female gonad development GO:0008585 23 23 0,000 0,01330807 0,01882332 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,01330807 0,01880888 ! lipid homeostasis GO:0055088 23 23 0,000 0,01330807 0,01879447 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,01330807 0,01878008 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,01330807 0,01876571 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,01330807 0,01875136 ! cell projection assembly GO:0030031 25 23 0,000 0,01330807 0,01873704 ! mitochondrial transport GO:0006839 24 24 0,000 0,01388366 0,0195325 ! regulation of action potential GO:0001508 24 24 0,000 0,01388366 0,0195176 ! gliogenesis GO:0042063 24 24 0,000 0,01388366 0,01950273 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,01388366 0,01948788 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,01388366 0,01947304 ! glucose homeostasis GO:0042593 24 24 0,000 0,01388366 0,01945824 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,01388366 0,01944345 ! T cell differentiation GO:0030217 24 24 0,000 0,01388366 0,01942869 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,01388366 0,01941395 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,01388366 0,01939923 ! ovulation cycle GO:0042698 24 24 0,000 0,01388366 0,01938453 ! fertilization GO:0009566 25 24 0,000 0,01388366 0,01936986 ! maintenance of protein location GO:0045185 25 24 0,000 0,01388366 0,0193552 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,01388366 0,01934057 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,01388366 0,01932597 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,01388366 0,01931138 ! glucan metabolic process GO:0044042 25 24 0,000 0,01388366 0,01929682 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,01445899 0,02008132 ! negative regulation of secretion GO:0051048 26 25 0,000 0,01445899 0,0200662 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,01445899 0,0200511 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,01445899 0,02003603 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,01445899 0,02002097 ! cellular component disassembly GO:0022411 26 25 0,000 0,01445899 0,02000594 ! endosome transport GO:0016197 25 25 0,000 0,01445899 0,01999093 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,01445899 0,01997595 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,01445899 0,01996098 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,01445899 0,01994604 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,01445899 0,01993112 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,01445899 0,01991623 ! excretion GO:0007588 25 25 0,000 0,01445899 0,01990135 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,01445899 0,0198865 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,01445899 0,01987167 ! gastrulation GO:0007369 25 25 0,000 0,01445899 0,01985687 ! heart morphogenesis GO:0003007 25 25 0,000 0,01445899 0,01984208 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,01445899 0,01982732 ! regulation of endocytosis GO:0030100 25 25 0,000 0,01445899 0,01981258 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,01445899 0,01979786 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,01445899 0,01978316 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,01445899 0,01976848 ! positive regulation of binding GO:0051099 27 26 0,000 0,01503407 0,0205395 ! positive regulation of defense response GO:0031349 26 26 0,000 0,01503407 0,02052428 ! glycolysis GO:0006096 26 26 0,000 0,01503407 0,02050909 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,01503407 0,02049392 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,01503407 0,02047878 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,01503407 0,02046365 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,01503407 0,02044855 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,01503407 0,02043347 ! cellular defense response GO:0006968 26 26 0,000 0,01503407 0,02041841 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,01503407 0,02040338 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,01503407 0,02038836 ! double-strand break repair GO:0006302 27 26 0,000 0,01503407 0,02037337 ! regulation of protein secretion GO:0050708 26 26 0,000 0,01503407 0,0203584 ! germ cell development GO:0007281 27 26 0,000 0,01503407 0,02034345 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,01503407 0,02032853 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,01503407 0,02031362 ! response to insulin stimulus GO:0032868 28 26 0,000 0,01503407 0,02029874 ! maintenance of location in cell GO:0051651 27 26 0,000 0,01503407 0,02028388 ! synapse organization GO:0050808 26 26 0,000 0,01503407 0,02026904 ! chloride transport GO:0006821 27 27 0,000 0,01560889 0,02102865 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,01560889 0,02101329 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,01560889 0,02099795 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,01560889 0,02098263 ! learning or memory GO:0007611 28 27 0,000 0,01560889 0,02096734 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,01560889 0,02095207 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,01560889 0,02093682 ! peptide metabolic process GO:0006518 29 27 0,000 0,01560889 0,02092159 ! activation of caspase activity GO:0006919 27 27 0,000 0,01560889 0,02090639 ! mesenchymal cell development GO:0014031 29 27 0,000 0,01560889 0,02089121 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,01560889 0,02087604 ! defense response to bacterium GO:0042742 27 27 0,000 0,01560889 0,02086091 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,01560889 0,02084579 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,01560889 0,0208307 ! cell growth GO:0016049 27 27 0,000 0,01560889 0,02081562 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,01618347 0,02156626 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,01618347 0,02155067 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,01618347 0,02153511 ! carbohydrate transport GO:0008643 28 28 0,000 0,01618347 0,02151958 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,01618347 0,02150406 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,01618347 0,02148857 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,01618347 0,0214731 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,01618347 0,02145765 ! histone modification GO:0016570 28 28 0,000 0,01618347 0,02144222 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,01618347 0,02142682 ! developmental growth GO:0048589 28 28 0,000 0,01618347 0,02141144 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,01618347 0,02139608 ! cartilage development GO:0051216 29 28 0,000 0,01618347 0,02138074 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,01675779 0,02212365 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,01675779 0,02210781 ! viral reproductive process GO:0022415 29 29 0,000 0,01675779 0,022092 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,01675779 0,0220762 ! leukocyte migration GO:0050900 30 29 0,000 0,01675779 0,02206044 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,01675779 0,02204469 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,01675779 0,02202897 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,01675779 0,02201326 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,01675779 0,02199759 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,01675779 0,02198193 ! tRNA processing GO:0008033 29 29 0,000 0,01675779 0,02196629 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,01675779 0,02195068 ! covalent chromatin modification GO:0016569 29 29 0,000 0,01675779 0,02193509 ! adult behavior GO:0030534 30 29 0,000 0,01675779 0,02191953 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,01675779 0,02190398 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,01675779 0,02188846 ! response to UV GO:0009411 29 29 0,000 0,01675779 0,02187295 ! transition metal ion transport GO:0000041 31 30 0,000 0,01733186 0,02260625 ! RNA catabolic process GO:0006401 30 30 0,000 0,01733186 0,02259026 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,01733186 0,02257429 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,01733186 0,02255835 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,01733186 0,02254243 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,01733186 0,02252653 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,01733186 0,02251066 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,01733186 0,02249481 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,01733186 0,02247898 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,01733186 0,02246317 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,01733186 0,02244738 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,01733186 0,02243162 ! response to temperature stimulus GO:0009266 30 30 0,000 0,01733186 0,02241588 ! regulation of ossification GO:0030278 30 30 0,000 0,01733186 0,02240016 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,01733186 0,02238446 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,01733186 0,02236879 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,01733186 0,02235313 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,01733186 0,0223375 ! vesicle organization GO:0016050 30 30 0,000 0,01733186 0,02232189 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,01733186 0,0223063 ! establishment of organelle localization GO:0051656 31 30 0,000 0,01733186 0,02229074 ! regulation of translational initiation GO:0006446 31 31 0,000 0,01790569 0,02301268 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,01790569 0,02299664 ! membrane fusion GO:0006944 31 31 0,000 0,01790569 0,02298063 ! B cell activation GO:0042113 31 31 0,000 0,01790569 0,02296463 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,01790569 0,02294866 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,01790569 0,02293272 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,01790569 0,02291679 ! ion transmembrane transport GO:0034220 31 31 0,000 0,01790569 0,02290089 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,01790569 0,02288501 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,01790569 0,02286915 ! digestion GO:0007586 31 31 0,000 0,01790569 0,02285331 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,01790569 0,02283749 ! regulation of DNA replication GO:0006275 32 31 0,000 0,01790569 0,0228217 ! regulation of heart contraction GO:0008016 31 31 0,000 0,01790569 0,02280593 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,01790569 0,02279018 ! camera-type eye development GO:0043010 31 31 0,000 0,01790569 0,02277445 ! extracellular matrix organization GO:0030198 31 31 0,000 0,01790569 0,02275874 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,01790569 0,02274306 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,01790569 0,0227274 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,01790569 0,02271175 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,01790569 0,02269613 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,01790569 0,02268053 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,01847925 0,02339098 ! cell redox homeostasis GO:0045454 32 32 0,000 0,01847925 0,02337493 ! muscle fiber development GO:0048747 32 32 0,000 0,01847925 0,02335889 ! glucose catabolic process GO:0006007 32 32 0,000 0,01847925 0,02334288 ! lipid modification GO:0030258 32 32 0,000 0,01847925 0,02332689 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,01847925 0,02331093 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,01847925 0,02329498 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,01847925 0,02327906 ! cell maturation GO:0048469 32 32 0,000 0,01847925 0,02326316 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,01847925 0,02324728 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,01847925 0,02323142 ! nuclear export GO:0051168 32 32 0,000 0,01847925 0,02321559 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,01847925 0,02319977 ! kidney development GO:0001822 32 32 0,000 0,01847925 0,02318398 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,01847925 0,02316821 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,01847925 0,02315246 ! maintenance of location GO:0051235 33 32 0,000 0,01847925 0,02313673 ! negative regulation of cell size GO:0045792 33 33 0,000 0,01905257 0,02383835 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,01905257 0,02382218 ! amino acid transport GO:0006865 33 33 0,000 0,01905257 0,02380603 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,01905257 0,0237899 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,01905257 0,02377379 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,01905257 0,02375771 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,01905257 0,02374164 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,01905257 0,0237256 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,01905257 0,02370958 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,01905257 0,02369358 ! regulation of actin filament length GO:0030832 34 34 0,000 0,01962564 0,02438979 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,01962564 0,02437335 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,01962564 0,02435694 ! response to metal ion GO:0010038 34 34 0,000 0,01962564 0,02434055 ! ear development GO:0043583 34 34 0,000 0,01962564 0,02432418 ! muscle cell differentiation GO:0042692 35 34 0,000 0,01962564 0,02430783 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,01962564 0,02429151 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,01962564 0,0242752 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,01962564 0,02425892 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,01962564 0,02424266 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,01962564 0,02422643 ! secondary metabolic process GO:0019748 34 34 0,000 0,01962564 0,02421021 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,01962564 0,02419402 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,01962564 0,02417784 ! viral reproduction GO:0016032 34 34 0,000 0,01962564 0,02416169 ! detection of stimulus GO:0051606 36 34 0,000 0,01962564 0,02414556 ! acute inflammatory response GO:0002526 35 35 0,000 0,02019846 0,02483372 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,02019846 0,02481717 ! regulation of cellular component size GO:0032535 35 35 0,000 0,02019846 0,02480064 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,02019846 0,02478412 ! mesoderm development GO:0007498 35 35 0,000 0,02019846 0,02476763 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,02019846 0,02475117 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,02019846 0,02473472 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,02019846 0,0247183 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,02019846 0,02470189 ! inorganic anion transport GO:0015698 35 35 0,000 0,02019846 0,02468551 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,02019846 0,02466915 ! regulation of immune effector process GO:0002697 35 35 0,000 0,02019846 0,02465282 ! hydrogen transport GO:0006818 36 36 0,000 0,02077102 0,02533487 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,02077102 0,02531812 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,02077102 0,02530138 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,02077102 0,02528467 ! regulation of mitosis GO:0007088 37 36 0,000 0,02077102 0,02526798 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,02077102 0,02525131 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,02077102 0,02523467 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,02077102 0,02521804 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,02077102 0,02520144 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,02077102 0,02518486 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,02077102 0,0251683 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,02077102 0,02515177 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,02077102 0,02513525 ! gonad development GO:0008406 36 36 0,000 0,02077102 0,02511876 ! regulation of lipase activity GO:0060191 36 36 0,000 0,02077102 0,02510229 ! activation of immune response GO:0002253 36 36 0,000 0,02077102 0,02508584 ! coagulation GO:0050817 39 36 0,000 0,02077102 0,02506941 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,02134333 0,0257433 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,02134333 0,02572647 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,02134333 0,02570965 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,02134333 0,02569286 ! response to drug GO:0042493 37 37 0,000 0,02134333 0,02567609 ! lung development GO:0030324 38 37 0,000 0,02134333 0,02565934 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,02134333 0,02564261 ! eye development GO:0001654 37 37 0,000 0,02134333 0,02562591 ! negative regulation of growth GO:0045926 37 37 0,000 0,02134333 0,02560922 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,02134333 0,02559256 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,02134333 0,02557592 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,02134333 0,0255593 ! adaptive immune response GO:0002250 37 37 0,000 0,02134333 0,0255427 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,0219154 0,0262103 ! neurotransmitter transport GO:0006836 40 38 0,000 0,0219154 0,02619331 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,0219154 0,02617633 ! exocytosis GO:0006887 40 38 0,000 0,0219154 0,02615938 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,0219154 0,02614244 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,0219154 0,02612553 ! chromosome segregation GO:0007059 38 38 0,000 0,0219154 0,02610865 ! urogenital system development GO:0001655 38 38 0,000 0,0219154 0,02609178 ! hexose catabolic process GO:0019320 38 38 0,000 0,0219154 0,02607494 ! RNA elongation GO:0006354 38 38 0,000 0,0219154 0,02605811 ! meiotic cell cycle GO:0051321 38 38 0,000 0,0219154 0,02604131 ! axon guidance GO:0007411 39 38 0,000 0,0219154 0,02602453 ! regulation of neurological system process GO:0031644 38 38 0,000 0,0219154 0,02600778 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,0219154 0,02599104 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,0219154 0,02597433 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,02248721 0,02663491 ! hemostasis GO:0007599 42 39 0,000 0,02248721 0,02661781 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,02248721 0,02660072 ! activation of MAPK activity GO:0000187 39 39 0,000 0,02248721 0,02658366 ! respiratory tube development GO:0030323 40 39 0,000 0,02248721 0,02656662 ! response to unfolded protein GO:0006986 39 39 0,000 0,02248721 0,0265496 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,02248721 0,0265326 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,02248721 0,02651563 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,02248721 0,02649867 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,02248721 0,02648174 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,02248721 0,02646483 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,02248721 0,02644794 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,02248721 0,02643108 ! respiratory system development GO:0060541 40 39 0,000 0,02248721 0,02641423 ! developmental maturation GO:0021700 39 39 0,000 0,02248721 0,02639741 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,02248721 0,0263806 ! protein oligomerization GO:0051259 39 39 0,000 0,02248721 0,02636382 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,02248721 0,02634706 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,02305877 0,02699956 ! DNA catabolic process GO:0006308 41 40 0,000 0,02305877 0,02698242 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,02305877 0,0269653 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,02305877 0,0269482 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,02305877 0,02693112 ! organelle localization GO:0051640 41 40 0,000 0,02305877 0,02691407 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,02363008 0,02756344 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,02363008 0,02754601 ! amine catabolic process GO:0009310 42 41 0,000 0,02363008 0,0275286 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,02363008 0,02751121 ! regulation of caspase activity GO:0043281 41 41 0,000 0,02363008 0,02749384 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,02363008 0,02747649 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,02363008 0,02745917 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,02363008 0,02744187 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,02363008 0,02742458 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,02420114 0,02806967 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,02420114 0,02805201 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,02420114 0,02803438 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,02420114 0,02801677 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,02420114 0,02799919 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,02420114 0,02798162 ! protein ubiquitination GO:0016567 43 42 0,000 0,02420114 0,02796408 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,02420114 0,02794656 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,02420114 0,02792906 ! forebrain development GO:0030900 43 42 0,000 0,02420114 0,02791158 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,02420114 0,02789412 ! reproductive structure development GO:0048608 43 43 0,000 0,02477195 0,02853419 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,02477195 0,02851637 ! mitochondrion organization GO:0007005 44 43 0,000 0,02477195 0,02849857 ! alcohol catabolic process GO:0046164 43 43 0,000 0,02477195 0,02848079 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,02477195 0,02846303 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,02477195 0,0284453 ! humoral immune response GO:0006959 44 44 0,000 0,02534251 0,02908234 ! mRNA transport GO:0051028 44 44 0,000 0,02534251 0,02906425 ! protein import into nucleus GO:0006606 44 44 0,000 0,02534251 0,02904617 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,02534251 0,02902812 ! vitamin metabolic process GO:0006766 44 44 0,000 0,02534251 0,02901009 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,02534251 0,02899208 ! amine biosynthetic process GO:0009309 46 45 0,000 0,02591282 0,02962613 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,02591282 0,02960776 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,02591282 0,02958942 ! regulation of DNA binding GO:0051101 47 45 0,000 0,02591282 0,0295711 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,02591282 0,0295528 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,02591282 0,02953452 ! nuclear import GO:0051170 45 45 0,000 0,02591282 0,02951627 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,02591282 0,02949804 ! protein processing GO:0016485 45 45 0,000 0,02591282 0,02947983 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,02648288 0,03010977 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,02648288 0,03009121 ! tube morphogenesis GO:0035239 47 46 0,000 0,02648288 0,03007267 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,02648288 0,03005415 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,02648288 0,03003566 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,02648288 0,03001718 ! regulation of membrane potential GO:0042391 46 46 0,000 0,02648288 0,02999874 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,02705268 0,03062537 ! regulation of blood pressure GO:0008217 48 47 0,000 0,02705268 0,03060657 ! sex differentiation GO:0007548 47 47 0,000 0,02705268 0,03058779 ! amine transport GO:0015837 47 47 0,000 0,02705268 0,03056904 ! rhythmic process GO:0048511 47 47 0,000 0,02705268 0,03055031 ! regulation of catabolic process GO:0009894 48 47 0,000 0,02705268 0,0305316 ! calcium ion transport GO:0006816 48 48 0,000 0,02762224 0,03115532 ! actin filament organization GO:0007015 50 48 0,000 0,02762224 0,03113627 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,02762224 0,03111723 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,02762224 0,03109822 ! protein localization in nucleus GO:0034504 48 48 0,000 0,02762224 0,03107924 ! DNA recombination GO:0006310 48 48 0,000 0,02762224 0,03106028 ! leukocyte differentiation GO:0002521 50 49 0,000 0,02819155 0,03168111 ! ossification GO:0001503 50 49 0,000 0,02819155 0,03166181 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,02819155 0,03164253 ! cell cycle arrest GO:0007050 49 49 0,000 0,02819155 0,03162327 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,02819155 0,03160403 ! divalent metal ion transport GO:0070838 49 49 0,000 0,02819155 0,03158482 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,02819155 0,03156563 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,02819155 0,03154647 ! response to bacterium GO:0009617 50 49 0,000 0,02819155 0,03152732 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,02819155 0,0315082 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,02819155 0,03148911 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,02819155 0,03147004 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,02876061 0,03208584 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,02876061 0,03206643 ! negative regulation of transport GO:0051051 51 50 0,000 0,02876061 0,03204704 ! chromatin assembly GO:0031497 50 50 0,000 0,02876061 0,03202767 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,02876061 0,03200833 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,02876061 0,03198902 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,02876061 0,03196972 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,02876061 0,03195045 ! transcription initiation GO:0006352 50 50 0,000 0,02876061 0,03193121 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,02876061 0,03191198 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,02932942 0,03252353 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,02932942 0,03250398 ! positive regulation of immune response GO:0050778 51 51 0,000 0,02932942 0,03248444 ! rRNA metabolic process GO:0016072 51 51 0,000 0,02932942 0,03246493 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,02932942 0,03244545 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,02932942 0,03242598 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,02932942 0,03240654 ! protein maturation GO:0051604 51 51 0,000 0,02932942 0,03238713 ! RNA localization GO:0006403 52 52 0,000 0,02989797 0,03299519 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,02989797 0,03297544 ! cell fate commitment GO:0045165 52 52 0,000 0,02989797 0,03295572 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,02989797 0,03293602 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,02989797 0,03291635 ! response to light stimulus GO:0009416 53 52 0,000 0,02989797 0,0328967 ! sodium ion transport GO:0006814 53 53 0,000 0,03046628 0,033502 ! tRNA metabolic process GO:0006399 53 53 0,000 0,03046628 0,03348203 ! response to hypoxia GO:0001666 53 53 0,000 0,03046628 0,03346207 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,03046628 0,03344214 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,03046628 0,03342224 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,03046628 0,03340235 ! regulation of T cell activation GO:0050863 53 53 0,000 0,03046628 0,0333825 ! regulation of protein transport GO:0051223 53 53 0,000 0,03046628 0,03336266 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,03103434 0,03396454 ! response to oxygen levels GO:0070482 55 54 0,000 0,03103434 0,03394439 ! response to virus GO:0009615 54 54 0,000 0,03103434 0,03392425 ! hormone metabolic process GO:0042445 55 54 0,000 0,03103434 0,03390414 ! sulfur metabolic process GO:0006790 55 54 0,000 0,03103434 0,03388406 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,03103434 0,033864 ! nucleosome organization GO:0034728 55 55 0,000 0,03160215 0,03446317 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,03160215 0,03444279 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,03160215 0,03442244 ! in utero embryonic development GO:0001701 55 55 0,000 0,03160215 0,0344021 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,03160215 0,0343818 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,03160215 0,03436151 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,03216971 0,034958 ! reproductive developmental process GO:0003006 56 56 0,000 0,03216971 0,0349374 ! extracellular structure organization GO:0043062 56 56 0,000 0,03216971 0,03491683 ! regulation of nervous system development GO:0051960 57 56 0,000 0,03216971 0,03489628 ! regulation of binding GO:0051098 60 57 0,000 0,03273702 0,03549078 ! ATP metabolic process GO:0046034 57 57 0,000 0,03273702 0,03546991 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,03273702 0,03544907 ! regulation of protein localization GO:0032880 58 57 0,000 0,03273702 0,03542826 ! innate immune response GO:0045087 58 58 0,000 0,03330408 0,03602078 ! dephosphorylation GO:0016311 60 59 0,000 0,03387089 0,03661235 ! carboxylic acid transport GO:0046942 59 59 0,000 0,03387089 0,03659088 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,03387089 0,03656945 ! regulation of cell development GO:0060284 60 59 0,000 0,03387089 0,03654804 ! sterol metabolic process GO:0016125 59 59 0,000 0,03387089 0,03652665 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,03387089 0,03650529 ! protein localization in organelle GO:0033365 59 59 0,000 0,03387089 0,03648396 ! immune effector process GO:0002252 59 59 0,000 0,03387089 0,03646265 ! potassium ion transport GO:0006813 60 60 0,000 0,03443745 0,03705092 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,03443745 0,0370293 ! protein polymerization GO:0051258 65 60 0,000 0,03443745 0,03700771 ! cellular respiration GO:0045333 62 61 0,000 0,03500376 0,03759437 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,03500376 0,03757247 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,03500376 0,0375506 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,03500376 0,03752876 ! lipid transport GO:0006869 62 62 0,000 0,03556983 0,03811348 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,03556983 0,03809134 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,03556983 0,03806922 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,03556983 0,03804712 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,03556983 0,03802505 ! protein import GO:0017038 62 62 0,000 0,03556983 0,03800301 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,03556983 0,03798099 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,03556983 0,037959 ! regulation of secretion GO:0051046 65 63 0,000 0,03613564 0,0385405 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,03613564 0,03851821 ! glucose metabolic process GO:0006006 63 63 0,000 0,03613564 0,03849595 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,03613564 0,03847371 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,03613564 0,03845149 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,03670121 0,03903077 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,03670121 0,03900826 ! angiogenesis GO:0001525 65 64 0,000 0,03670121 0,03898578 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,03670121 0,03896332 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,03670121 0,03894089 ! anion transport GO:0006820 65 65 0,000 0,03726652 0,03951795 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,03726652 0,03949523 ! regulation of hormone levels GO:0010817 66 65 0,000 0,03726652 0,03947253 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,03783159 0,04004803 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,03783159 0,04002504 ! DNA packaging GO:0006323 66 66 0,000 0,03783159 0,04000208 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,03783159 0,03997914 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,03783159 0,03995623 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,03783159 0,03993334 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,03839641 0,04050634 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,03839641 0,04048317 ! muscle contraction GO:0006936 67 67 0,000 0,03839641 0,04046002 ! striated muscle tissue development GO:0014706 69 67 0,000 0,03839641 0,0404369 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,03839641 0,04041381 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,03839641 0,04039074 ! response to radiation GO:0009314 70 68 0,000 0,03896098 0,04096126 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,03896098 0,0409379 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,03896098 0,04091458 ! regulation of cell size GO:0008361 68 68 0,000 0,03896098 0,04089128 ! regulation of translation GO:0006417 69 69 0,000 0,0395253 0,04145995 ! sensory perception of sound GO:0007605 71 69 0,000 0,0395253 0,04143636 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,0395253 0,04141281 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,0395253 0,04138928 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,0395253 0,04136577 ! positive regulation of transport GO:0051050 71 70 0,000 0,04008937 0,0419323 ! cell part morphogenesis GO:0032990 75 70 0,000 0,04008937 0,04190852 ! wound healing GO:0042060 74 70 0,000 0,04008937 0,04188476 ! growth GO:0040007 70 70 0,000 0,04008937 0,04186103 ! muscle tissue development GO:0060537 72 70 0,000 0,04008937 0,04183732 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,04008937 0,04181365 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,0406532 0,04237774 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,0406532 0,04235378 ! regulation of cell migration GO:0030334 71 71 0,000 0,0406532 0,04232985 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,0406532 0,04230595 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,0406532 0,04228208 ! regulation of cell activation GO:0050865 71 71 0,000 0,0406532 0,04225823 ! secretion by cell GO:0032940 75 72 0,000 0,04121677 0,0428199 ! muscle system process GO:0003012 72 72 0,000 0,04121677 0,04279578 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,04121677 0,04277168 ! sensory organ development GO:0007423 72 72 0,000 0,04121677 0,04274761 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,04121677 0,04272357 ! regulation of cytokine production GO:0001817 72 72 0,000 0,04121677 0,04269956 ! electron transport chain GO:0022900 75 74 0,000 0,04234318 0,04384184 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,04234318 0,04381722 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,04290601 0,04437473 ! response to oxidative stress GO:0006979 76 75 0,000 0,04290601 0,04434985 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,04290601 0,04432499 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,04346859 0,04488102 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,04403093 0,04543617 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,04403093 0,04541074 ! regulation of protein modification process GO:0031399 79 78 0,000 0,04459301 0,04596472 ! microtubule-based movement GO:0007018 82 78 0,000 0,04459301 0,04593903 ! metal ion homeostasis GO:0055065 78 78 0,000 0,04459301 0,04591337 ! regulation of immune response GO:0050776 78 78 0,000 0,04459301 0,04588773 ! regulation of locomotion GO:0040012 79 79 0,000 0,04515485 0,04643995 ! nuclear transport GO:0051169 79 79 0,000 0,04515485 0,04641405 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,04515485 0,04638818 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,04571644 0,04693894 ! neuron projection development GO:0031175 85 80 0,000 0,04571644 0,04691281 ! MAPKKK cascade GO:0000165 82 81 0,000 0,04627779 0,04746242 ! tube development GO:0035295 83 81 0,000 0,04627779 0,04743602 ! lymphocyte activation GO:0046649 82 81 0,000 0,04627779 0,04740965 ! lipid catabolic process GO:0016042 82 81 0,000 0,04627779 0,04738331 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,04739973 0,04850511 ! ncRNA processing GO:0034470 83 83 0,000 0,04739973 0,04847819 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,04739973 0,0484513 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,04796033 0,04899717 ! regulation of cellular localization GO:0060341 86 85 0,000 0,04852068 0,04954217 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,04852068 0,04951474 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,04852068 0,04948734 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,04852068 0,04945997 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,04908079 0,05000326 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,04908079 0,04997563 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,04908079 0,04994804 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,04908079 0,04992047 ! heart development GO:0007507 90 87 0,000 0,04964065 0,05046206 ! male gamete generation GO:0048232 90 88 0,000 0,05020026 0,0510028 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,05020026 0,0509747 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,05020026 0,05094663 ! chemotaxis GO:0006935 90 89 0,000 0,05075962 0,05148596 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,05075962 0,05145764 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,05187761 0,05256208 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,05187761 0,0525332 ! DNA replication GO:0006260 91 91 0,000 0,05187761 0,05250436 ! visual perception GO:0007601 93 92 0,000 0,05243623 0,0530406 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,05243623 0,05301151 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,05243623 0,05298244 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,05243623 0,05295341 ! tissue morphogenesis GO:0048729 94 93 0,000 0,05299461 0,05348799 ! regulation of response to stress GO:0080134 97 94 0,000 0,05355274 0,05402173 ! blood vessel development GO:0001568 95 94 0,000 0,05355274 0,05399217 ! epidermis development GO:0008544 94 94 0,000 0,05355274 0,05396265 ! cofactor metabolic process GO:0051186 95 94 0,000 0,05355274 0,05393317 ! regulation of cell growth GO:0001558 97 96 0,000 0,05466825 0,05502654 ! vasculature development GO:0001944 97 96 0,000 0,05466825 0,0549965 ! endocytosis GO:0006897 99 98 0,000 0,05578279 0,05608711 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,05578279 0,05605653 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,05578279 0,05602598 ! blood circulation GO:0008015 99 98 0,000 0,05578279 0,05599546 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,05578279 0,05596498 ! ectoderm development GO:0007398 99 99 0,000 0,05633968 0,05649294 ! response to hormone stimulus GO:0009725 102 100 0,000 0,05689633 0,05702009 ! muscle organ development GO:0007517 102 100 0,000 0,05689633 0,0569891 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,05689633 0,05695814 ! response to other organism GO:0051707 101 100 0,000 0,05689633 0,05692722 ! hemopoiesis GO:0030097 104 100 0,000 0,05689633 0,05689633