pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/1501-1-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 2,517E-08 6,056E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 7,142E-07 8,592E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,223E-06 9,807E-04 ! fructose metabolic process GO:0006000 25 16 2,000 1,394E-06 8,388E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,828E-06 1,361E-03 ! alditol metabolic process GO:0019400 38 24 2,000 5,001E-06 2,005E-03 ! sperm motility GO:0030317 31 25 2,000 5,677E-06 1,951E-03 ! osteoblast differentiation GO:0001649 60 25 2,000 5,677E-06 1,707E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 7,206E-06 1,926E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 9,485E-06 2,282E-03 ! interphase GO:0051325 213 98 3,000 1,073E-05 2,347E-03 ! cell cycle arrest GO:0007050 213 100 3,000 1,162E-05 2,331E-03 ! hexose biosynthetic process GO:0019319 48 32 2,000 1,216E-05 2,251E-03 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 1,6E-05 2,75E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 1,744E-05 2,797E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,744E-05 2,622E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,894E-05 2,68E-03 ! skeletal myofibril assembly GO:0014866 10 5 1,000 1,894E-05 2,531E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,894E-05 2,398E-03 ! learning GO:0007612 77 39 2,000 2,225E-05 2,677E-03 ! polyol metabolic process GO:0019751 66 41 2,000 2,591E-05 2,968E-03 ! alcohol biosynthetic process GO:0046165 59 42 2,000 2,787E-05 3,048E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,838E-05 2,969E-03 GO:0046530|photoreceptor cell differentiation, ! striated muscle cell differentiation GO:0051146 82 43 2,000 2,994E-05 3,001E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,671E-05 3,533E-03 ! neuron adhesion GO:0007158 12 7 1,000 3,969E-05 3,673E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 5,288E-05 4,712E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 1,000 5,288E-05 4,544E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 1,000 5,288E-05 4,387E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,483E-05 6,804E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,483E-05 6,584E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 8,483E-05 6,378E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 8,483E-05 6,185E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 8,483E-05 6,003E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 1,036E-04 7,121E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! Golgi vesicle budding GO:0048194 22 11 1,000 1,036E-04 6,923E-03 ! actin filament organization GO:0007015 148 66 2,000 1,086E-04 7,059E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,242E-04 7,864E-03 ! learning or memory GO:0007611 147 73 2,000 1,465E-04 9,04E-03 ! regulation of synaptic transmission GO:0050804 134 79 2,000 1,852E-04 0,01114217 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,923E-04 0,01128299 ! muscle cell differentiation GO:0042692 159 80 2,000 1,923E-04 0,01101435 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 2,068E-04 0,01157379 ! regulation of cyclase activity GO:0031279 159 82 2,000 2,068E-04 0,01131075 ! regulation of lyase activity GO:0051339 160 83 2,000 2,144E-04 0,01146301 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 2,221E-04 0,01161788 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 2,221E-04 0,01137069 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,25E-04 0,01127915 ! alcohol catabolic process GO:0046164 130 86 2,000 2,381E-04 0,01169157 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 2,464E-04 0,01185545 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! membrane budding GO:0006900 37 17 1,000 2,548E-04 0,01202046 ! regulation of neurological system process GO:0031644 148 88 2,000 2,548E-04 0,01179038 ! ossification GO:0001503 188 90 2,000 2,723E-04 0,0123603 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 2,723E-04 0,0121314 ! bone development GO:0060348 189 91 2,000 2,813E-04 0,01230496 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 2,999E-04 0,01288404 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 2,999E-04 0,012658 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 3,198E-04 0,01326636 ! visual learning GO:0008542 36 19 1,000 3,198E-04 0,01304151 ! G1 phase GO:0051318 40 19 1,000 3,198E-04 0,01282415 ! cell-cell junction organization GO:0045216 35 19 1,000 3,198E-04 0,01261392 ! cell aging GO:0007569 44 21 1,000 3,92E-04 0,01521399 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 3,92E-04 0,0149725 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 4,309E-04 0,01619807 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,309E-04 0,01594887 ! visual behavior GO:0007632 42 23 1,000 4,715E-04 0,01718794 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,139E-04 0,0184543 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 5,139E-04 0,01818291 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 5,139E-04 0,01791939 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,581E-04 0,01918238 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 6,041E-04 0,02047011 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 6,041E-04 0,02018581 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,518E-04 0,02148303 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 7,526E-04 0,02447022 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 7,526E-04 0,02414395 ! myofibril assembly GO:0030239 47 30 1,000 8,057E-04 0,02550559 GO:0055002|striated muscle cell development, ! eye morphogenesis GO:0048592 60 30 1,000 8,057E-04 0,02517435 ! regulation of B cell activation GO:0050864 50 30 1,000 8,057E-04 0,0248516 ! muscle cell development GO:0055001 49 32 1,000 9,17E-04 0,02792844 ! protein targeting to membrane GO:0006612 68 33 1,000 9,753E-04 0,02933272 ! cell junction organization GO:0034330 86 36 1,000 1,161E-03 0,03447569 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 1,161E-03 0,03405525 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 1,226E-03 0,03553611 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 1,226E-03 0,03511306 ! actomyosin structure organization GO:0031032 62 37 1,000 1,226E-03 0,03469997 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 1,226E-03 0,03429648 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,293E-03 0,03575413 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 1,504E-03 0,04112168 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 1,653E-03 0,0446962 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,809E-03 0,04837253 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,89E-03 0,04997143 ! response to insulin stimulus GO:0032868 95 46 1,000 1,89E-03 0,04942826 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 2,056E-03 0,05319643 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 2,142E-03 0,05482171 ! vesicle organization GO:0016050 107 51 1,000 2,318E-03 0,05870748 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,318E-03 0,05809594 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! morphogenesis of a branching structure GO:0001763 111 52 1,000 2,409E-03 0,05974417 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 2,501E-03 0,06139935 ! response to UV GO:0009411 104 53 1,000 2,501E-03 0,06077916 ! aging GO:0007568 103 55 1,000 2,69E-03 0,06472932 ! skeletal muscle fiber development GO:0048741 111 56 1,000 2,788E-03 0,0664035 ! muscle fiber development GO:0048747 112 57 1,000 2,886E-03 0,06808343 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 3,298E-03 0,07703555 ! regulation of mitosis GO:0007088 105 63 1,000 3,513E-03 0,08127945 GO:0051783|regulation of nuclear division, ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 3,963E-03 0,09081983 ! negative regulation of cell growth GO:0030308 132 67 1,000 3,963E-03 0,08996304 ! negative regulation of kinase activity GO:0033673 131 68 1,000 4,08E-03 0,09174209 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 4,08E-03 0,09089263 ! negative regulation of cell size GO:0045792 134 69 1,000 4,198E-03 0,09266541 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 4,198E-03 0,091823 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 4,562E-03 0,09887959 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 4,562E-03 0,09799673 ! negative regulation of transferase activity GO:0051348 140 72 1,000 4,562E-03 0,09712951 ! eye development GO:0001654 143 74 1,000 4,812E-03 0,10156025 ! positive regulation of ligase activity GO:0051351 124 77 1,000 5,199E-03 0,10877614 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 5,199E-03 0,10783841 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 5,331E-03 0,10963378 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 5,465E-03 0,11143008 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 5,875E-03 0,11878683 ! negative regulation of growth GO:0045926 155 84 1,000 6,156E-03 0,12343219 ! regulation of ligase activity GO:0051340 142 84 1,000 6,156E-03 0,12241209 ! positive regulation of cell activation GO:0050867 145 85 1,000 6,299E-03 0,12422491 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,954E-03 0,13602401 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,954E-03 0,13492704 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,954E-03 0,13384762 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,954E-03 0,13278534 ! neuron fate determination GO:0048664 7 5 0,000 6,954E-03 0,13173978 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,954E-03 0,13071057 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,954E-03 0,12969731 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,954E-03 0,12869964 ! polyol transport GO:0015791 12 5 0,000 6,954E-03 0,1277172 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,954E-03 0,12674964 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,954E-03 0,12579664 ! response to superoxide GO:0000303 10 5 0,000 6,954E-03 0,12485786 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,954E-03 0,12393298 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,954E-03 0,12302171 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,954E-03 0,12212374 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,954E-03 0,12123879 ! female meiosis GO:0007143 7 5 0,000 6,954E-03 0,12036657 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,954E-03 0,1195068 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,954E-03 0,11865924 ! cobalt ion transport GO:0006824 11 5 0,000 6,954E-03 0,11782361 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,954E-03 0,11699967 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,954E-03 0,11618717 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,954E-03 0,11538588 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,954E-03 0,11459557 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,954E-03 0,113816 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,954E-03 0,11304698 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,954E-03 0,11228827 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,954E-03 0,11153968 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,954E-03 0,11080101 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,954E-03 0,11007206 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,954E-03 0,10935263 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,954E-03 0,10864255 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,954E-03 0,10794163 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,954E-03 0,1072497 ! negative chemotaxis GO:0050919 14 5 0,000 6,954E-03 0,10656658 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,954E-03 0,10589211 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,954E-03 0,10522612 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,954E-03 0,10456845 ! behavioral response to pain GO:0048266 9 5 0,000 6,954E-03 0,10391896 ! clathrin coat assembly GO:0048268 14 5 0,000 6,954E-03 0,10327749 ! Notch receptor processing GO:0007220 8 5 0,000 6,954E-03 0,10264388 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,954E-03 0,102018 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,954E-03 0,10139971 ! micturition GO:0060073 9 5 0,000 6,954E-03 0,10078887 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,954E-03 0,10018535 ! copulation GO:0007620 9 5 0,000 6,954E-03 0,099589 ! glial cell fate commitment GO:0021781 13 5 0,000 6,954E-03 0,09899972 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,954E-03 0,09841737 ! spermidine metabolic process GO:0008216 7 5 0,000 6,954E-03 0,09784183 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,954E-03 0,09727298 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,954E-03 0,09671071 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,954E-03 0,0961549 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,954E-03 0,09560544 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,954E-03 0,09506223 ! grooming behavior GO:0007625 6 5 0,000 6,954E-03 0,09452516 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,954E-03 0,09399412 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,954E-03 0,09346901 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,954E-03 0,09294974 ! response to protozoan GO:0001562 10 5 0,000 6,954E-03 0,0924362 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,954E-03 0,09192831 ! lymph vessel development GO:0001945 10 5 0,000 6,954E-03 0,09142597 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,954E-03 0,09092909 ! endochondral ossification GO:0001958 16 5 0,000 6,954E-03 0,09043758 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,954E-03 0,08995136 ! parathyroid gland development GO:0060017 13 5 0,000 6,954E-03 0,08947034 ! anagen GO:0042640 6 5 0,000 6,954E-03 0,08899443 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,954E-03 0,08852356 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,954E-03 0,08805765 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,954E-03 0,08759661 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,954E-03 0,08714038 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,954E-03 0,08668887 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,954E-03 0,08624202 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,954E-03 0,08579976 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,954E-03 0,085362 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,954E-03 0,08492869 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,954E-03 0,08449976 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,954E-03 0,08407514 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,954E-03 0,08365476 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,954E-03 0,08323857 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,954E-03 0,0828265 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,954E-03 0,08241849 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,954E-03 0,08201447 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,954E-03 0,0816144 ! histidine catabolic process GO:0006548 6 5 0,000 6,954E-03 0,08121822 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,954E-03 0,08082586 ! microvillus organization GO:0032528 7 5 0,000 6,954E-03 0,08043727 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,954E-03 0,08005241 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,954E-03 0,0796712 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,954E-03 0,07929361 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,954E-03 0,07891959 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,954E-03 0,07854907 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,954E-03 0,07818202 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,954E-03 0,07781838 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,954E-03 0,07745811 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,954E-03 0,07710116 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,954E-03 0,07674749 ! muscle cell migration GO:0014812 8 5 0,000 6,954E-03 0,07639704 ! mitochondrial fission GO:0000266 8 5 0,000 6,954E-03 0,07604978 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,954E-03 0,07570567 ! mRNA transcription GO:0009299 9 5 0,000 6,954E-03 0,07536465 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,954E-03 0,07502669 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,954E-03 0,07469175 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,954E-03 0,07435979 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,954E-03 0,07403076 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,954E-03 0,07370464 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,954E-03 0,07338137 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,954E-03 0,07306093 ! response to food GO:0032094 6 5 0,000 6,954E-03 0,07274327 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,954E-03 0,07242837 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,954E-03 0,07211618 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,954E-03 0,07180666 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,954E-03 0,0714998 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,954E-03 0,07119554 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,954E-03 0,07089387 ! forebrain neuron development GO:0021884 13 5 0,000 6,954E-03 0,07059474 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,954E-03 0,07029812 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,954E-03 0,07000399 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,954E-03 0,0697123 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,954E-03 0,06942304 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,954E-03 0,06913617 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,954E-03 0,06885166 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,954E-03 0,06856948 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,954E-03 0,0682896 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,954E-03 0,068012 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,954E-03 0,06773665 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,954E-03 0,06746352 ! basic amino acid transport GO:0015802 11 5 0,000 6,954E-03 0,06719258 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,954E-03 0,06692381 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,954E-03 0,06665718 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,954E-03 0,06639267 ! depyrimidination GO:0045008 10 5 0,000 6,954E-03 0,06613025 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,954E-03 0,06586989 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,954E-03 0,06561158 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,954E-03 0,06535528 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,954E-03 0,06510098 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,954E-03 0,06484865 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,954E-03 0,06459827 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,954E-03 0,06434982 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,954E-03 0,06410327 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,954E-03 0,0638586 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,954E-03 0,06361579 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,954E-03 0,06337482 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,954E-03 0,06313567 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,954E-03 0,06289832 ! response to arsenic GO:0046685 10 5 0,000 6,954E-03 0,06266274 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,954E-03 0,06242893 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,954E-03 0,06219685 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,954E-03 0,06196649 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,954E-03 0,06173783 ! response to cadmium ion GO:0046686 7 5 0,000 6,954E-03 0,06151086 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,954E-03 0,06128554 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,954E-03 0,06106187 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,954E-03 0,06083983 ! decidualization GO:0046697 11 5 0,000 6,954E-03 0,06061939 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,954E-03 0,06040055 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,954E-03 0,06018328 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,954E-03 0,05996757 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,954E-03 0,0597534 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,954E-03 0,05954076 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,954E-03 0,05932962 ! neural tube patterning GO:0021532 7 5 0,000 6,954E-03 0,05911997 ! embryonic cleavage GO:0040016 6 5 0,000 6,954E-03 0,05891181 ! peroxisome fission GO:0016559 5 5 0,000 6,954E-03 0,0587051 ! histone demethylation GO:0016577 10 5 0,000 6,954E-03 0,05849983 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,954E-03 0,058296 ! mitotic recombination GO:0006312 9 5 0,000 6,954E-03 0,05809359 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,954E-03 0,05789257 ! metaphase plate congression GO:0051310 7 5 0,000 6,954E-03 0,05769294 ! regulation of sterol transport GO:0032371 7 5 0,000 6,954E-03 0,05749468 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,954E-03 0,05729778 ! enteric nervous system development GO:0048484 8 5 0,000 6,954E-03 0,05710223 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,954E-03 0,056908 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,954E-03 0,05671509 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,954E-03 0,05652349 ! muscle cell proliferation GO:0033002 11 5 0,000 6,954E-03 0,05633317 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,954E-03 0,05614414 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,954E-03 0,05595636 ! plasminogen activation GO:0031639 5 5 0,000 6,954E-03 0,05576984 ! B cell homeostasis GO:0001782 13 5 0,000 6,954E-03 0,05558456 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,954E-03 0,05540051 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,954E-03 0,05521767 ! metaphase GO:0051323 8 5 0,000 6,954E-03 0,05503603 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,954E-03 0,05485558 ! cellular response to nutrient GO:0031670 8 5 0,000 6,954E-03 0,05467632 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,954E-03 0,05449822 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,954E-03 0,05432127 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,954E-03 0,05414548 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,954E-03 0,05397082 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,954E-03 0,05379728 ! response to redox state GO:0051775 5 5 0,000 6,954E-03 0,05362485 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,954E-03 0,05345352 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,954E-03 0,05328329 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,954E-03 0,05311414 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,954E-03 0,05294605 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,954E-03 0,05277903 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,954E-03 0,05261306 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,954E-03 0,05244813 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,954E-03 0,05228423 ! striatum development GO:0021756 9 5 0,000 6,954E-03 0,05212135 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,954E-03 0,05195948 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,954E-03 0,05179862 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,954E-03 0,05163874 ! glial cell migration GO:0008347 11 5 0,000 6,954E-03 0,05147985 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,954E-03 0,05132194 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,954E-03 0,05116499 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,954E-03 0,051009 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,954E-03 0,05085396 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,954E-03 0,05069986 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,954E-03 0,05054668 ! neuroprotection GO:0043526 6 5 0,000 6,954E-03 0,05039444 ! neural plate development GO:0001840 8 5 0,000 6,954E-03 0,0502431 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,954E-03 0,05009267 ! regulation of sensory perception GO:0051931 7 5 0,000 6,954E-03 0,04994314 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,954E-03 0,0497945 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,954E-03 0,04964674 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,954E-03 0,04949986 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,954E-03 0,04935384 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,954E-03 0,04920868 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,954E-03 0,04906438 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,954E-03 0,04892091 ! spindle assembly GO:0051225 6 5 0,000 6,954E-03 0,04877829 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,954E-03 0,04863649 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,954E-03 0,04849551 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,954E-03 0,04835535 ! drug metabolic process GO:0017144 6 5 0,000 6,954E-03 0,048216 ! stem cell division GO:0017145 11 5 0,000 6,954E-03 0,04807745 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,954E-03 0,04793969 ! organ regeneration GO:0031100 7 5 0,000 6,954E-03 0,04780272 ! carnitine metabolic process GO:0009437 7 5 0,000 6,954E-03 0,04766653 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,954E-03 0,04753112 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,954E-03 0,04739647 ! regulation of cell cycle process GO:0010564 149 90 1,000 7,036E-03 0,04781786 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 7,495E-03 0,05079934 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 7,495E-03 0,05065665 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,339E-03 0,05620025 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,339E-03 0,05604326 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 8,339E-03 0,05588715 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,339E-03 0,05573191 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,339E-03 0,05557753 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 8,339E-03 0,055424 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 8,339E-03 0,05527132 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,339E-03 0,05511947 ! sleep GO:0030431 13 6 0,000 8,339E-03 0,05496846 ! response to oxygen radical GO:0000305 11 6 0,000 8,339E-03 0,05481827 ! positive regulation of axon extension GO:0045773 11 6 0,000 8,339E-03 0,0546689 ! myoblast cell fate commitment GO:0048625 16 6 0,000 8,339E-03 0,05452035 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 8,339E-03 0,0543726 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 8,339E-03 0,05422564 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,339E-03 0,05407948 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,339E-03 0,05393411 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 8,339E-03 0,05378951 ! forebrain regionalization GO:0021871 8 6 0,000 8,339E-03 0,05364569 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,339E-03 0,05350263 ! male meiosis GO:0007140 7 6 0,000 8,339E-03 0,05336034 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,339E-03 0,0532188 ! response to zinc ion GO:0010043 9 6 0,000 8,339E-03 0,05307801 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,339E-03 0,05293796 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 8,339E-03 0,05279865 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 8,339E-03 0,05266007 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,339E-03 0,05252222 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,339E-03 0,05238509 ! malate metabolic process GO:0006108 11 6 0,000 8,339E-03 0,05224867 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 8,339E-03 0,05211296 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 8,339E-03 0,05197795 ! protein refolding GO:0042026 15 6 0,000 8,339E-03 0,05184364 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,339E-03 0,05171002 ! opsonization GO:0008228 8 6 0,000 8,339E-03 0,05157709 ! mating behavior GO:0007617 7 6 0,000 8,339E-03 0,05144484 ! neuron remodeling GO:0016322 15 6 0,000 8,339E-03 0,05131327 ! erythrocyte maturation GO:0043249 7 6 0,000 8,339E-03 0,05118237 ! embryonic hemopoiesis GO:0035162 14 6 0,000 8,339E-03 0,05105213 ! equilibrioception GO:0050957 14 6 0,000 8,339E-03 0,05092256 ! protein amino acid dealkylation GO:0008214 12 6 0,000 8,339E-03 0,05079364 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 8,339E-03 0,05066537 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 8,339E-03 0,05053775 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,339E-03 0,05041077 ! response to interferon-gamma GO:0034341 15 6 0,000 8,339E-03 0,05028443 ! toxin metabolic process GO:0009404 11 6 0,000 8,339E-03 0,05015872 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,339E-03 0,05003364 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,339E-03 0,04990917 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 8,339E-03 0,04978533 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 8,339E-03 0,0496621 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 8,339E-03 0,04953948 ! cGMP-mediated signaling GO:0019934 13 6 0,000 8,339E-03 0,04941746 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,339E-03 0,04929604 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 8,339E-03 0,04917522 ! thymic T cell selection GO:0045061 12 6 0,000 8,339E-03 0,04905498 ! protein lipoylation GO:0009249 10 6 0,000 8,339E-03 0,04893534 ! cysteine metabolic process GO:0006534 10 6 0,000 8,339E-03 0,04881627 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,339E-03 0,04869779 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,339E-03 0,04857987 ! glutamate catabolic process GO:0006538 10 6 0,000 8,339E-03 0,04846253 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 8,339E-03 0,04834575 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,339E-03 0,04822954 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 8,339E-03 0,04811388 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 8,339E-03 0,04799877 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,339E-03 0,04788422 ! hyperosmotic response GO:0006972 9 6 0,000 8,339E-03 0,04777021 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 8,339E-03 0,04765674 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 8,339E-03 0,04754381 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,339E-03 0,04743141 ! urea metabolic process GO:0019627 7 6 0,000 8,339E-03 0,04731955 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,339E-03 0,04720821 ! neutrophil activation GO:0042119 8 6 0,000 8,339E-03 0,04709739 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,339E-03 0,04698709 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 8,339E-03 0,04687731 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,339E-03 0,04676804 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,339E-03 0,04665927 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,339E-03 0,04655102 ! neuron apoptosis GO:0051402 9 6 0,000 8,339E-03 0,04644326 ! nucleoside salvage GO:0043174 9 6 0,000 8,339E-03 0,046336 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 8,339E-03 0,04622923 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,339E-03 0,04612296 ! T cell mediated immunity GO:0002456 16 6 0,000 8,339E-03 0,04601717 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,339E-03 0,04591187 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 8,339E-03 0,04580705 ! carnitine transport GO:0015879 10 6 0,000 8,339E-03 0,04570271 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 8,339E-03 0,04559884 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,339E-03 0,04549544 ! positive regulation of exocytosis GO:0045921 8 6 0,000 8,339E-03 0,04539251 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 8,339E-03 0,04529004 ! 5S class rRNA transcription GO:0042791 11 6 0,000 8,339E-03 0,04518804 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,339E-03 0,04508649 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 8,339E-03 0,0449854 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 8,339E-03 0,04488476 ! sodium ion homeostasis GO:0055078 11 6 0,000 8,339E-03 0,04478457 ! establishment of spindle localization GO:0051293 12 6 0,000 8,339E-03 0,04468483 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 8,339E-03 0,04458553 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,339E-03 0,04448667 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 8,339E-03 0,04438825 ! neural nucleus development GO:0048857 14 6 0,000 8,339E-03 0,04429026 ! response to UV-C GO:0010225 11 6 0,000 8,339E-03 0,0441927 ! astrocyte development GO:0014002 15 6 0,000 8,339E-03 0,04409558 ! protein targeting to lysosome GO:0006622 10 6 0,000 8,339E-03 0,04399888 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,339E-03 0,0439026 ! interaction with symbiont GO:0051702 13 6 0,000 8,339E-03 0,04380674 ! regulation of dendrite development GO:0050773 16 6 0,000 8,339E-03 0,0437113 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,339E-03 0,04361628 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 8,339E-03 0,04352167 ! response to copper ion GO:0046688 10 6 0,000 8,339E-03 0,04342746 ! response to exogenous dsRNA GO:0043330 10 6 0,000 8,339E-03 0,04333367 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 8,339E-03 0,04324028 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,339E-03 0,04314729 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,339E-03 0,0430547 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,339E-03 0,0429625 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 8,339E-03 0,0428707 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,339E-03 0,04277929 ! nucleoside catabolic process GO:0009164 7 6 0,000 8,339E-03 0,04268827 ! hair follicle maturation GO:0048820 7 6 0,000 8,339E-03 0,04259764 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,339E-03 0,04250739 ! Schwann cell development GO:0014044 15 6 0,000 8,339E-03 0,04241752 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 8,339E-03 0,04232803 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,339E-03 0,04223892 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 8,339E-03 0,04215018 ! subpallium development GO:0021544 10 6 0,000 8,339E-03 0,04206182 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 8,339E-03 0,04197382 ! histone ubiquitination GO:0016574 8 6 0,000 8,339E-03 0,0418862 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 8,339E-03 0,04179893 ! maintenance of organ identity GO:0048496 9 6 0,000 8,339E-03 0,04171203 ! G2 phase GO:0051319 16 6 0,000 8,339E-03 0,04162549 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 8,339E-03 0,04153931 ! establishment of planar polarity GO:0001736 7 6 0,000 8,339E-03 0,04145349 ! regulation of mast cell activation GO:0033003 12 6 0,000 8,339E-03 0,04136802 ! membrane to membrane docking GO:0022614 14 6 0,000 8,339E-03 0,0412829 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,339E-03 0,04119813 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 8,339E-03 0,0411137 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,339E-03 0,04102963 ! receptor internalization GO:0031623 10 6 0,000 8,339E-03 0,04094589 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 8,339E-03 0,0408625 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 8,339E-03 0,04077945 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,339E-03 0,04069673 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 8,339E-03 0,04061435 ! protein deubiquitination GO:0016579 14 6 0,000 8,339E-03 0,0405323 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 8,339E-03 0,04045058 ! protein destabilization GO:0031648 9 6 0,000 8,339E-03 0,04036919 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,339E-03 0,04028813 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 8,339E-03 0,04020739 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,339E-03 0,04012698 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 8,339E-03 0,04004688 ! progesterone metabolic process GO:0042448 10 6 0,000 8,339E-03 0,03996711 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 8,339E-03 0,03988765 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 8,339E-03 0,03980851 ! negative regulation of axon extension GO:0030517 21 6 0,000 8,339E-03 0,03972968 ! removal of superoxide radicals GO:0019430 11 6 0,000 8,339E-03 0,03965116 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,339E-03 0,03957295 ! determination of adult lifespan GO:0008340 15 6 0,000 8,339E-03 0,03949505 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 8,339E-03 0,03941746 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 8,339E-03 0,03934017 ! cerebellar cortex formation GO:0021697 8 6 0,000 8,339E-03 0,03926319 ! catecholamine transport GO:0051937 9 6 0,000 8,339E-03 0,0391865 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 8,339E-03 0,03911011 ! sensory cilium assembly GO:0035058 10 6 0,000 8,339E-03 0,03903402 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,339E-03 0,03895823 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 8,339E-03 0,03888273 ! maternal placenta development GO:0001893 12 6 0,000 8,339E-03 0,03880752 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 8,339E-03 0,0387326 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,339E-03 0,03865797 ! negative regulation of B cell activation GO:0050869 13 6 0,000 8,339E-03 0,03858363 ! protein amino acid prenylation GO:0018346 16 6 0,000 8,339E-03 0,03850957 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,339E-03 0,0384358 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 8,339E-03 0,03836231 ! positive regulation of coagulation GO:0050820 12 6 0,000 8,339E-03 0,0382891 ! Golgi vesicle transport GO:0048193 207 99 1,000 8,455E-03 0,03874611 ! skeletal muscle tissue development GO:0007519 186 99 1,000 8,455E-03 0,03867245 GO:0060538|skeletal muscle organ development, ! tRNA transcription GO:0009304 14 7 0,000 9,722E-03 0,04438612 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,722E-03 0,04430206 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 9,722E-03 0,04421831 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,722E-03 0,04413488 ! regulation of helicase activity GO:0051095 15 7 0,000 9,722E-03 0,04405176 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,722E-03 0,04396896 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,722E-03 0,04388646 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,722E-03 0,04380428 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,722E-03 0,0437224 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,722E-03 0,04364083 ! prostate gland development GO:0030850 13 7 0,000 9,722E-03 0,04355956 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,722E-03 0,0434786 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,722E-03 0,04339793 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,722E-03 0,04331757 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,722E-03 0,0432375 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,722E-03 0,04315772 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,722E-03 0,04307824 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,722E-03 0,04299905 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 9,722E-03 0,04292016 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,722E-03 0,04284155 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,722E-03 0,04276323 ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,722E-03 0,04268519 ! glycolipid transport GO:0046836 10 7 0,000 9,722E-03 0,04260744 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,722E-03 0,04252997 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,722E-03 0,04245279 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 9,722E-03 0,04237588 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,722E-03 0,04229925 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,722E-03 0,0422229 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 9,722E-03 0,04214682 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,722E-03 0,04207102 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,722E-03 0,04199549 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,722E-03 0,04192022 ! mRNA stabilization GO:0048255 18 7 0,000 9,722E-03 0,04184523 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,722E-03 0,04177051 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,722E-03 0,04169605 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,722E-03 0,04162186 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,722E-03 0,04154793 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,722E-03 0,04147426 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,722E-03 0,04140086 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,722E-03 0,04132771 ! lipoprotein transport GO:0042953 14 7 0,000 9,722E-03 0,04125482 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,722E-03 0,04118219 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,722E-03 0,04110982 ! rhythmic behavior GO:0007622 15 7 0,000 9,722E-03 0,04103769 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,722E-03 0,04096582 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,722E-03 0,04089421 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,722E-03 0,04082284 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,722E-03 0,04075172 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,722E-03 0,04068084 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,722E-03 0,04061022 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,722E-03 0,04053984 ! mechanosensory behavior GO:0007638 14 7 0,000 9,722E-03 0,0404697 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,722E-03 0,0403998 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,722E-03 0,04033015 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,722E-03 0,04026073 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,722E-03 0,04019156 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,722E-03 0,04012262 ! spinal cord patterning GO:0021511 13 7 0,000 9,722E-03 0,04005391 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,722E-03 0,03998545 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,722E-03 0,03991721 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,722E-03 0,03984921 ! adrenal gland development GO:0030325 17 7 0,000 9,722E-03 0,03978144 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,722E-03 0,0397139 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,722E-03 0,03964659 ! ovulation GO:0030728 9 7 0,000 9,722E-03 0,0395795 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,722E-03 0,03951264 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,722E-03 0,03944601 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,722E-03 0,03937961 ! microtubule nucleation GO:0007020 20 7 0,000 9,722E-03 0,03931342 ! proline biosynthetic process GO:0006561 10 7 0,000 9,722E-03 0,03924746 ! thyroid hormone generation GO:0006590 13 7 0,000 9,722E-03 0,03918172 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 9,722E-03 0,0391162 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,722E-03 0,03905089 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,722E-03 0,03898581 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,722E-03 0,03892094 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,722E-03 0,03885629 ! galactose metabolic process GO:0006012 13 7 0,000 9,722E-03 0,03879185 ! vesicle fusion GO:0006906 17 7 0,000 9,722E-03 0,03872762 ! response to dietary excess GO:0002021 8 7 0,000 9,722E-03 0,03866361 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,722E-03 0,03859981 ! intracellular pH reduction GO:0051452 11 7 0,000 9,722E-03 0,03853622 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,722E-03 0,03847284 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,722E-03 0,03840966 ! organ growth GO:0035265 15 7 0,000 9,722E-03 0,0383467 ! purine salvage GO:0043101 10 7 0,000 9,722E-03 0,03828394 ! nucleoside transport GO:0015858 8 7 0,000 9,722E-03 0,03822138 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,722E-03 0,03815903 ! parturition GO:0007567 14 7 0,000 9,722E-03 0,03809688 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,722E-03 0,03803494 ! rRNA modification GO:0000154 14 7 0,000 9,722E-03 0,03797319 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,722E-03 0,03791165 ! spindle checkpoint GO:0031577 15 7 0,000 9,722E-03 0,0378503 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 9,722E-03 0,03778915 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,722E-03 0,0377282 ! macrophage differentiation GO:0030225 11 7 0,000 9,722E-03 0,03766745 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,722E-03 0,03760689 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,722E-03 0,03754653 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,722E-03 0,03748635 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,722E-03 0,03742638 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,722E-03 0,03736659 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,722E-03 0,03730699 ! fibrinolysis GO:0042730 10 7 0,000 9,722E-03 0,03724759 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,722E-03 0,03718837 ! eating behavior GO:0042755 7 7 0,000 9,722E-03 0,03712934 ! B cell lineage commitment GO:0002326 21 7 0,000 9,722E-03 0,0370705 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,722E-03 0,03701184 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,722E-03 0,03695337 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,722E-03 0,03689509 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,722E-03 0,03683698 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,722E-03 0,03677907 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,722E-03 0,03672133 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,722E-03 0,03666377 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,722E-03 0,03660639 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,722E-03 0,0365492 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,722E-03 0,03649218 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,722E-03 0,03643534 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,722E-03 0,03637867 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,722E-03 0,03632218 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,722E-03 0,03626587 ! regulation of meiosis GO:0040020 12 7 0,000 9,722E-03 0,03620973 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,722E-03 0,03615376 ! T cell lineage commitment GO:0002360 16 7 0,000 9,722E-03 0,03609797 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,722E-03 0,03604235 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,722E-03 0,0359869 ! oxygen homeostasis GO:0032364 12 7 0,000 9,722E-03 0,03593162 ! transcription termination GO:0006353 13 7 0,000 9,722E-03 0,03587651 ! response to tumor cell GO:0002347 13 7 0,000 9,722E-03 0,03582157 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,722E-03 0,0357668 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,722E-03 0,03571219 ! anaphase GO:0051322 17 7 0,000 9,722E-03 0,03565775 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,722E-03 0,03560348 ! axonal fasciculation GO:0007413 18 7 0,000 9,722E-03 0,03554937 ! negative regulation of nuclear division GO:0051784 14 7 0,000 9,722E-03 0,03549543 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,722E-03 0,03544164 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,722E-03 0,03538803 ! diuresis GO:0030146 12 7 0,000 9,722E-03 0,03533457 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,722E-03 0,03528128 ! thiamin metabolic process GO:0006772 7 7 0,000 9,722E-03 0,03522814 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,722E-03 0,03517517 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,722E-03 0,03512235 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,722E-03 0,03506969 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,722E-03 0,03501719 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,722E-03 0,03496485 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,722E-03 0,03491266 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,722E-03 0,03486063 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,722E-03 0,03480876 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,722E-03 0,03475704 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,722E-03 0,03470547 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,722E-03 0,03465405 ! lymph node development GO:0048535 10 7 0,000 9,722E-03 0,03460279 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,722E-03 0,03455168 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,722E-03 0,03450072 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,722E-03 0,0344499 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,722E-03 0,03439924 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,722E-03 0,03434873 ! adult feeding behavior GO:0008343 9 7 0,000 9,722E-03 0,03429837 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,722E-03 0,03424815 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,722E-03 0,03419808 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,722E-03 0,03414815 ! muscle adaptation GO:0043500 14 7 0,000 9,722E-03 0,03409838 ! embryonic heart tube development GO:0035050 10 7 0,000 9,722E-03 0,03404874 ! retina homeostasis GO:0001895 12 7 0,000 9,722E-03 0,03399925 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,722E-03 0,03394991 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,722E-03 0,0339007 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,722E-03 0,03385164 ! protein prenylation GO:0018342 18 7 0,000 9,722E-03 0,03380272 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 9,722E-03 0,03375395 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 9,722E-03 0,03370531 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,722E-03 0,03365681 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01110347 0,03838355 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01110347 0,03832848 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01110347 0,03827357 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01110347 0,03821881 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01110347 0,03816422 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01110347 0,03810977 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01110347 0,03805549 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01110347 0,03800135 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01110347 0,03794737 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01110347 0,03789355 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01110347 0,03783987 ! meiotic prophase I GO:0007128 13 8 0,000 0,01110347 0,03778635 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01110347 0,03773298 ! oligopeptide transport GO:0006857 15 8 0,000 0,01110347 0,03767976 ! UTP metabolic process GO:0046051 8 8 0,000 0,01110347 0,03762669 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01110347 0,03757377 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01110347 0,037521 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01110347 0,03746837 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01110347 0,0374159 ! succinate metabolic process GO:0006105 14 8 0,000 0,01110347 0,03736357 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01110347 0,03731138 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01110347 0,03725935 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01110347 0,03720745 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01110347 0,0371557 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01110347 0,0371041 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01110347 0,03705264 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01110347 0,03700132 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01110347 0,03695014 ! reflex GO:0060004 16 8 0,000 0,01110347 0,0368991 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01110347 0,03684821 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01110347 0,03679745 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01110347 0,03674684 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01110347 0,03669636 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01110347 0,03664602 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01110347 0,03659582 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01110347 0,03654576 ! pigment granule organization GO:0048753 16 8 0,000 0,01110347 0,03649584 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01110347 0,03644605 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01110347 0,03639639 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01110347 0,03634687 ! histidine metabolic process GO:0006547 16 8 0,000 0,01110347 0,03629749 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01110347 0,03624824 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01110347 0,03619912 ! glycine catabolic process GO:0006546 13 8 0,000 0,01110347 0,03615014 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01110347 0,03610129 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01110347 0,03605257 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01110347 0,03600398 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01110347 0,03595552 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01110347 0,03590719 ! melanin metabolic process GO:0006582 15 8 0,000 0,01110347 0,035859 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01110347 0,03581093 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01110347 0,03576299 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01110347 0,03571518 ! macrophage activation GO:0042116 12 8 0,000 0,01110347 0,03566749 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01110347 0,03561994 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01110347 0,03557251 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01110347 0,0355252 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01110347 0,03547802 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01110347 0,03543097 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01110347 0,03538404 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01110347 0,03533724 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01110347 0,03529056 ! osteoblast development GO:0002076 16 8 0,000 0,01110347 0,035244 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01110347 0,03519756 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01110347 0,03515125 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01110347 0,03510506 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01110347 0,03505899 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01110347 0,03501304 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01110347 0,03496721 ! response to UV-B GO:0010224 16 8 0,000 0,01110347 0,0349215 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01110347 0,03487592 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01110347 0,03483044 ! intermediate filament organization GO:0045109 12 8 0,000 0,01110347 0,03478509 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01110347 0,03473986 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01110347 0,03469474 ! cellular extravasation GO:0045123 12 8 0,000 0,01110347 0,03464974 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01110347 0,03460486 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01110347 0,03456009 ! response to antibiotic GO:0046677 11 8 0,000 0,01110347 0,03451544 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01110347 0,0344709 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01110347 0,03442648 ! DNA topological change GO:0006265 12 8 0,000 0,01110347 0,03438218 ! response to tropane GO:0014073 15 8 0,000 0,01110347 0,03433798 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01110347 0,0342939 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01110347 0,03424994 ! melanosome transport GO:0032402 13 8 0,000 0,01110347 0,03420608 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01110347 0,03416234 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01110347 0,03411871 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01110347 0,03407519 ! mast cell activation GO:0045576 14 8 0,000 0,01110347 0,03403179 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01110347 0,03398849 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01110347 0,0339453 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01110347 0,03390222 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01110347 0,03385925 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01110347 0,03381639 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01110347 0,03377364 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01110347 0,033731 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01110347 0,03368846 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01110347 0,03364603 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01110347 0,03360371 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01110347 0,0335615 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01110347 0,03351939 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01110347 0,03347738 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01110347 0,03343548 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01110347 0,03339369 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01110347 0,033352 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01110347 0,03331041 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01110347 0,03326893 ! hormone catabolic process GO:0042447 17 8 0,000 0,01110347 0,03322755 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01110347 0,03318627 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01110347 0,0331451 ! ATP catabolic process GO:0006200 11 8 0,000 0,01110347 0,03310403 ! blastocyst growth GO:0001832 19 8 0,000 0,01110347 0,03306306 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01110347 0,03302219 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01110347 0,03298142 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01110347 0,03294075 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01110347 0,03290019 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01110347 0,03285972 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01110347 0,03281935 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01110347 0,03277908 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01110347 0,03273891 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01110347 0,03269884 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01110347 0,03265886 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01110347 0,03261899 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01110347 0,03257921 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01110347 0,03253953 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01110347 0,03249994 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01110347 0,03246045 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01110347 0,03242106 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01248291 0,03640472 ! axon extension GO:0048675 15 9 0,000 0,01248291 0,03636064 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01248291 0,03631668 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01248291 0,03627282 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01248291 0,03622906 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01248291 0,03618541 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01248291 0,03614187 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01248291 0,03609843 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01248291 0,03605509 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01248291 0,03601186 ! phosphate transport GO:0006817 19 9 0,000 0,01248291 0,03596873 ! reproductive behavior GO:0019098 19 9 0,000 0,01248291 0,03592571 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01248291 0,03588279 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01248291 0,03583997 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01248291 0,03579725 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01248291 0,03575463 ! GTP metabolic process GO:0046039 9 9 0,000 0,01248291 0,03571212 ! RNA methylation GO:0001510 15 9 0,000 0,01248291 0,0356697 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01248291 0,03562739 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01248291 0,03558518 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01248291 0,03554307 ! artery development GO:0060840 24 9 0,000 0,01248291 0,03550105 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01248291 0,03545914 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01248291 0,03541732 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01248291 0,03537561 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01248291 0,03533399 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01248291 0,03529247 ! chemosensory behavior GO:0007635 20 9 0,000 0,01248291 0,03525105 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01248291 0,03520972 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01248291 0,03516849 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01248291 0,03512736 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01248291 0,03508632 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01248291 0,03504538 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01248291 0,03500454 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01248291 0,03496379 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01248291 0,03492313 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01248291 0,03488257 ! protein targeting to ER GO:0045047 22 9 0,000 0,01248291 0,0348421 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01248291 0,03480173 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01248291 0,03476145 ! T cell selection GO:0045058 23 9 0,000 0,01248291 0,03472126 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01248291 0,03468117 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01248291 0,03464117 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01248291 0,03460126 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01248291 0,03456144 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01248291 0,03452171 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01248291 0,03448208 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01248291 0,03444254 ! mannose metabolic process GO:0006013 13 9 0,000 0,01248291 0,03440308 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01248291 0,03436372 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01248291 0,03432445 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01248291 0,03428526 ! receptor clustering GO:0043113 18 9 0,000 0,01248291 0,03424617 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01248291 0,03420717 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01248291 0,03416825 ! ruffle organization GO:0031529 15 9 0,000 0,01248291 0,03412942 ! retinol metabolic process GO:0042572 18 9 0,000 0,01248291 0,03409068 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01248291 0,03405203 ! behavioral fear response GO:0001662 22 9 0,000 0,01248291 0,03401347 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01248291 0,03397499 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01248291 0,0339366 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01248291 0,0338983 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01248291 0,03386008 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01248291 0,03382195 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01248291 0,0337839 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01248291 0,03374595 ! segment specification GO:0007379 13 9 0,000 0,01248291 0,03370807 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01248291 0,03367028 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01248291 0,03363258 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01248291 0,03359496 ! response to amine stimulus GO:0014075 13 9 0,000 0,01248291 0,03355742 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01248291 0,03351997 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01248291 0,0334826 ! erythrocyte development GO:0048821 15 9 0,000 0,01248291 0,03344531 ! gas homeostasis GO:0033483 16 9 0,000 0,01248291 0,03340811 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01248291 0,03337099 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01248291 0,03333395 ! renal water homeostasis GO:0003091 14 9 0,000 0,01248291 0,033297 ! postreplication repair GO:0006301 22 9 0,000 0,01248291 0,03326012 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01248291 0,03322333 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01248291 0,03318662 ! icosanoid secretion GO:0032309 15 9 0,000 0,01248291 0,03314999 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01248291 0,03311344 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01248291 0,03307697 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01248291 0,03304058 ! regulation of cell division GO:0051302 15 9 0,000 0,01248291 0,03300428 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01248291 0,03296805 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01248291 0,0329319 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01248291 0,03289583 ! sterol catabolic process GO:0016127 11 9 0,000 0,01248291 0,03285984 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01248291 0,03282393 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01248291 0,03278809 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01248291 0,03275234 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01248291 0,03271666 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01248291 0,03268106 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01248291 0,03264553 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01248291 0,03261009 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01248291 0,03257472 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01248291 0,03253943 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01248291 0,03250421 ! purine base metabolic process GO:0006144 21 9 0,000 0,01248291 0,03246907 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01248291 0,03243401 ! pigment granule transport GO:0051904 17 9 0,000 0,01248291 0,03239902 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01248291 0,03236411 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01248291 0,03232927 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01248291 0,03229451 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01248291 0,03225982 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01248291 0,03222521 ! mitochondrion localization GO:0051646 15 9 0,000 0,01248291 0,03219067 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01386048 0,03570483 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01386048 0,03566664 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01386048 0,03562854 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01386048 0,03559051 ! synapsis GO:0007129 13 10 0,000 0,01386048 0,03555257 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01386048 0,03551471 ! N-glycan processing GO:0006491 20 10 0,000 0,01386048 0,03547693 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01386048 0,03543923 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01386048 0,03540161 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01386048 0,03536406 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01386048 0,0353266 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01386048 0,03528922 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01386048 0,03525192 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01386048 0,03521469 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01386048 0,03517754 ! androgen metabolic process GO:0008209 17 10 0,000 0,01386048 0,03514048 ! phospholipid efflux GO:0033700 16 10 0,000 0,01386048 0,03510349 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01386048 0,03506657 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01386048 0,03502974 ! lung alveolus development GO:0048286 26 10 0,000 0,01386048 0,03499298 ! pathogenesis GO:0009405 13 10 0,000 0,01386048 0,0349563 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01386048 0,0349197 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01386048 0,03488317 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01386048 0,03484672 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01386048 0,03481035 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01386048 0,03477405 ! endoderm development GO:0007492 16 10 0,000 0,01386048 0,03473783 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01386048 0,03470168 ! arginine catabolic process GO:0006527 13 10 0,000 0,01386048 0,03466561 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01386048 0,03462961 ! proline metabolic process GO:0006560 13 10 0,000 0,01386048 0,03459368 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01386048 0,03455784 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01386048 0,03452206 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01386048 0,03448636 ! V(D)J recombination GO:0033151 28 10 0,000 0,01386048 0,03445074 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01386048 0,03441518 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01386048 0,0343797 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01386048 0,0343443 ! B cell proliferation GO:0042100 18 10 0,000 0,01386048 0,03430896 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01386048 0,0342737 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01386048 0,03423851 ! multicellular organism growth GO:0035264 18 10 0,000 0,01386048 0,0342034 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01386048 0,03416835 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01386048 0,03413338 ! epithelial cell development GO:0002064 20 10 0,000 0,01386048 0,03409848 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01386048 0,03406365 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01386048 0,03402889 ! macroautophagy GO:0016236 17 10 0,000 0,01386048 0,0339942 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01386048 0,03395958 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01386048 0,03392504 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01386048 0,03389056 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01386048 0,03385615 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01386048 0,03382182 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01386048 0,03378755 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01386048 0,03375335 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01386048 0,03371922 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01386048 0,03368516 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01386048 0,03365117 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01386048 0,03361725 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01386048 0,0335834 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01386048 0,03354961 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01386048 0,03351589 ! response to dsRNA GO:0043331 20 10 0,000 0,01386048 0,03348224 ! DNA ligation GO:0006266 19 10 0,000 0,01386048 0,03344866 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01386048 0,03341514 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01386048 0,03338169 ! melanosome localization GO:0032400 16 10 0,000 0,01386048 0,03334831 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01386048 0,033315 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01386048 0,03328175 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01386048 0,03324857 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01386048 0,03321545 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01386048 0,0331824 ! mRNA cleavage GO:0006379 17 10 0,000 0,01386048 0,03314942 ! protein sumoylation GO:0016925 15 10 0,000 0,01386048 0,0331165 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01386048 0,03308364 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01386048 0,03305085 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01386048 0,03301813 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01386048 0,03298547 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01386048 0,03295288 ! salivary gland development GO:0007431 27 10 0,000 0,01386048 0,03292035 ! prophase GO:0051324 15 10 0,000 0,01386048 0,03288788 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01386048 0,03285548 ! apical protein localization GO:0045176 15 10 0,000 0,01386048 0,03282314 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01386048 0,03279087 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01386048 0,03275866 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01386048 0,03272651 ! midbrain development GO:0030901 13 10 0,000 0,01386048 0,03269442 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01386048 0,0326624 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01386048 0,03263044 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01386048 0,03259855 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01386048 0,03256671 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01386048 0,03253494 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01386048 0,03250323 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01386048 0,03247158 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01386048 0,03243999 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01386048 0,03240847 ! oocyte development GO:0048599 17 10 0,000 0,01386048 0,032377 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01386048 0,0323456 ! blastocyst formation GO:0001825 17 10 0,000 0,01386048 0,03231426 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01386048 0,03228297 ! activation of innate immune response GO:0002218 12 10 0,000 0,01386048 0,03225175 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01386048 0,03222059 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01386048 0,03218949 ! response to nicotine GO:0035094 20 10 0,000 0,01386048 0,03215845 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01386048 0,03212747 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01386048 0,03209655 ! localization within membrane GO:0051668 20 10 0,000 0,01386048 0,03206568 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01523617 0,03521443 ! respiratory burst GO:0045730 17 11 0,000 0,01523617 0,03518063 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01523617 0,0351469 ! neuron fate specification GO:0048665 17 11 0,000 0,01523617 0,03511324 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01523617 0,03507964 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01523617 0,0350461 ! thyroid gland development GO:0030878 26 11 0,000 0,01523617 0,03501263 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01523617 0,03497922 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01523617 0,03494587 ! response to pain GO:0048265 24 11 0,000 0,01523617 0,03491259 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01523617 0,03487937 ! T cell proliferation GO:0042098 26 11 0,000 0,01523617 0,03484622 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01523617 0,03481312 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01523617 0,03478009 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01523617 0,03474713 ! bone resorption GO:0045453 16 11 0,000 0,01523617 0,03471422 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01523617 0,03468138 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01523617 0,0346486 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01523617 0,03461588 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01523617 0,03458323 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01523617 0,03455063 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01523617 0,0345181 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01523617 0,03448562 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01523617 0,03445321 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01523617 0,03442086 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01523617 0,03438857 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01523617 0,03435634 ! lipid digestion GO:0044241 18 11 0,000 0,01523617 0,03432418 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01523617 0,03429207 ! UV protection GO:0009650 19 11 0,000 0,01523617 0,03426002 ! adult heart development GO:0007512 14 11 0,000 0,01523617 0,03422803 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01523617 0,0341961 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01523617 0,03416423 ! temperature homeostasis GO:0001659 17 11 0,000 0,01523617 0,03413242 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01523617 0,03410067 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01523617 0,03406898 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01523617 0,03403734 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01523617 0,03400577 ! regulation of organ growth GO:0046620 13 11 0,000 0,01523617 0,03397425 ! pigment granule localization GO:0051875 20 11 0,000 0,01523617 0,0339428 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01523617 0,0339114 ! vasoconstriction GO:0042310 18 11 0,000 0,01523617 0,03388005 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01523617 0,03384877 ! embryonic axis specification GO:0000578 18 11 0,000 0,01523617 0,03381755 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01523617 0,03378638 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01523617 0,03375527 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01523617 0,03372421 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01523617 0,03369322 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01523617 0,03366228 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01523617 0,03363139 ! zymogen activation GO:0031638 15 11 0,000 0,01523617 0,03360057 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01523617 0,0335698 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01523617 0,03353908 ! nucleosome positioning GO:0016584 15 11 0,000 0,01523617 0,03350843 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01523617 0,03347783 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01523617 0,03344728 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01523617 0,03341679 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01523617 0,03338636 ! acid secretion GO:0046717 18 11 0,000 0,01523617 0,03335598 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01523617 0,03332565 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01523617 0,03329539 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01523617 0,03326517 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01523617 0,03323501 ! oocyte differentiation GO:0009994 18 11 0,000 0,01523617 0,03320491 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01523617 0,03317486 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01523617 0,03314486 ! cholesterol efflux GO:0033344 19 11 0,000 0,01523617 0,03311492 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01523617 0,03308504 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01523617 0,0330552 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01523617 0,03302542 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01523617 0,0329957 ! embryonic gut development GO:0048566 15 11 0,000 0,01523617 0,03296602 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01523617 0,03293641 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01523617 0,03290684 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01523617 0,03287733 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01523617 0,03284787 ! defense response to fungus GO:0050832 13 11 0,000 0,01523617 0,03281846 ! developmental induction GO:0031128 19 11 0,000 0,01523617 0,0327891 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01523617 0,0327598 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01523617 0,03273055 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01523617 0,03270136 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01523617 0,03267221 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01523617 0,03264312 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01523617 0,03261407 ! nucleus localization GO:0051647 19 11 0,000 0,01523617 0,03258508 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01523617 0,03255614 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01660998 0,03546018 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01660998 0,03542874 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01660998 0,03539736 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01660998 0,03536603 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01660998 0,03533476 ! virus-host interaction GO:0019048 29 12 0,000 0,01660998 0,03530355 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01660998 0,03527239 ! cartilage condensation GO:0001502 20 12 0,000 0,01660998 0,03524129 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01660998 0,03521024 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01660998 0,03517924 ! protein complex disassembly GO:0043241 27 12 0,000 0,01660998 0,0351483 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01660998 0,03511742 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01660998 0,03508658 ! hippocampus development GO:0021766 26 12 0,000 0,01660998 0,03505581 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01660998 0,03502508 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01660998 0,03499441 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01660998 0,0349638 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01660998 0,03493323 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01660998 0,03490272 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01660998 0,03487227 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01660998 0,03484186 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01660998 0,03481151 ! drug transport GO:0015893 16 12 0,000 0,01660998 0,03478122 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01660998 0,03475097 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01660998 0,03472078 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01660998 0,03469064 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01660998 0,03466055 ! focal adhesion formation GO:0048041 35 12 0,000 0,01660998 0,03463052 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01660998 0,03460054 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01660998 0,0345706 ! forebrain cell migration GO:0021885 21 12 0,000 0,01660998 0,03454072 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01660998 0,0345109 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01660998 0,03448112 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01660998 0,0344514 ! entry into host cell GO:0030260 32 12 0,000 0,01660998 0,03442172 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01660998 0,0343921 ! monoamine transport GO:0015844 18 12 0,000 0,01660998 0,03436253 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01660998 0,03433301 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01660998 0,03430354 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01660998 0,03427412 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01660998 0,03424475 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01660998 0,03421543 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01660998 0,03418616 ! protein homotetramerization GO:0051289 21 12 0,000 0,01660998 0,03415694 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01660998 0,03412777 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01660998 0,03409865 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01660998 0,03406958 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01660998 0,03404056 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01660998 0,03401159 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01660998 0,03398267 ! cranial nerve development GO:0021545 20 12 0,000 0,01660998 0,0339538 ! fucose catabolic process GO:0019317 22 12 0,000 0,01660998 0,03392497 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01660998 0,0338962 ! histone acetylation GO:0016573 26 12 0,000 0,01660998 0,03386747 ! histone methylation GO:0016571 26 12 0,000 0,01660998 0,0338388 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01660998 0,03381017 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01660998 0,03378159 ! gland morphogenesis GO:0022612 29 12 0,000 0,01660998 0,03375306 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01660998 0,03372457 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01660998 0,03369614 ! T cell homeostasis GO:0043029 25 12 0,000 0,01660998 0,03366775 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01660998 0,03363941 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01660998 0,03361112 ! spleen development GO:0048536 22 12 0,000 0,01660998 0,03358287 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01660998 0,03355468 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01660998 0,03352653 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01660998 0,03349842 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01660998 0,03347037 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01660998 0,03344236 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01660998 0,0334144 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01660998 0,03338648 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01660998 0,03335861 ! response to cold GO:0009409 17 12 0,000 0,01660998 0,03333079 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01660998 0,03330302 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01660998 0,03327529 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01798193 0,03599377 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01798193 0,03596385 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01798193 0,03593398 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01798193 0,03590416 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01798193 0,03587439 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01798193 0,03584467 ! lipid localization GO:0010876 28 13 0,000 0,01798193 0,035815 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01798193 0,03578537 ! organelle fusion GO:0048284 32 13 0,000 0,01798193 0,0357558 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01798193 0,03572627 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01798193 0,0356968 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01798193 0,03566737 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01798193 0,03563799 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01798193 0,03560866 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01798193 0,03557937 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01798193 0,03555014 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01798193 0,03552095 ! methionine metabolic process GO:0006555 27 13 0,000 0,01798193 0,03549181 ! plasma membrane organization GO:0007009 24 13 0,000 0,01798193 0,03546272 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01798193 0,03543367 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01798193 0,03540468 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01798193 0,03537573 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01798193 0,03534683 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01798193 0,03531797 ! response to X-ray GO:0010165 25 13 0,000 0,01798193 0,03528917 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01798193 0,0352604 ! exocrine system development GO:0035272 32 13 0,000 0,01798193 0,03523169 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01798193 0,03520302 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01798193 0,0351744 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01798193 0,03514583 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01798193 0,0351173 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01798193 0,03508882 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01798193 0,03506039 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01798193 0,035032 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01798193 0,03500365 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01798193 0,03497536 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01798193 0,03494711 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01798193 0,0349189 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01798193 0,03489074 ! ribosome assembly GO:0042255 17 13 0,000 0,01798193 0,03486262 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01798193 0,03483455 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01798193 0,03480653 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01798193 0,03477855 ! chromatin silencing GO:0006342 26 13 0,000 0,01798193 0,03475062 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01798193 0,03472273 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01798193 0,03469488 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01798193 0,03466708 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01798193 0,03463932 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01798193 0,03461161 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01798193 0,03458395 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01798193 0,03455632 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01798193 0,03452874 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01798193 0,03450121 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01798193 0,03447372 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01798193 0,03444627 ! embryonic placenta development GO:0001892 23 13 0,000 0,01798193 0,03441887 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01798193 0,03439151 ! insulin secretion GO:0030073 23 13 0,000 0,01798193 0,03436419 ! actin filament polymerization GO:0030041 24 13 0,000 0,01798193 0,03433692 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01798193 0,03430969 ! acrosome reaction GO:0007340 18 13 0,000 0,01798193 0,0342825 ! rRNA transcription GO:0009303 25 14 0,000 0,019352 0,03686534 ! lactation GO:0007595 26 14 0,000 0,019352 0,03683617 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,019352 0,03680705 ! reproductive cellular process GO:0048610 20 14 0,000 0,019352 0,03677798 ! tRNA modification GO:0006400 20 14 0,000 0,019352 0,03674895 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,019352 0,03671997 ! regulation of S phase GO:0033261 23 14 0,000 0,019352 0,03669103 ! water transport GO:0006833 21 14 0,000 0,019352 0,03666214 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,019352 0,0366333 ! non-recombinational repair GO:0000726 25 14 0,000 0,019352 0,0366045 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,019352 0,03657574 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,019352 0,03654703 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,019352 0,03651837 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,019352 0,03648975 ! RNA polyadenylation GO:0043631 30 14 0,000 0,019352 0,03646117 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,019352 0,03643264 ! palate development GO:0060021 31 14 0,000 0,019352 0,03640416 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,019352 0,03637572 ! regulated secretory pathway GO:0045055 23 14 0,000 0,019352 0,03634732 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,019352 0,03631897 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,019352 0,03629066 ! arginine metabolic process GO:0006525 17 14 0,000 0,019352 0,0362624 ! regulation of heart rate GO:0002027 24 14 0,000 0,019352 0,03623418 ! organic alcohol transport GO:0015850 29 14 0,000 0,019352 0,036206 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,019352 0,03617787 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,019352 0,03614978 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,019352 0,03612174 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,019352 0,03609374 ! neutral amino acid transport GO:0015804 26 14 0,000 0,019352 0,03606578 ! L-amino acid transport GO:0015807 30 14 0,000 0,019352 0,03603786 ! bone mineralization GO:0030282 17 14 0,000 0,019352 0,03600999 ! stem cell development GO:0048864 43 14 0,000 0,019352 0,03598216 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,019352 0,03595438 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,019352 0,03592663 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,019352 0,03589893 ! cerebellum development GO:0021549 21 14 0,000 0,019352 0,03587128 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,019352 0,03584366 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,019352 0,03581609 ! response to gamma radiation GO:0010332 28 14 0,000 0,019352 0,03578856 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,019352 0,03576107 ! cofactor transport GO:0051181 26 14 0,000 0,019352 0,03573363 ! NADP metabolic process GO:0006739 24 14 0,000 0,019352 0,03570623 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,019352 0,03567886 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,019352 0,03565155 ! intestinal absorption GO:0050892 25 14 0,000 0,019352 0,03562427 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,019352 0,03559703 ! oxygen transport GO:0015671 21 14 0,000 0,019352 0,03556984 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,019352 0,03554269 ! male genitalia development GO:0030539 24 14 0,000 0,019352 0,03551557 ! regulation of RNA stability GO:0043487 32 14 0,000 0,019352 0,0354885 ! regulation of axon extension GO:0030516 37 14 0,000 0,019352 0,03546148 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,019352 0,03543449 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,019352 0,03540754 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02072021 0,03788209 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02072021 0,03785333 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02072021 0,03782461 ! superoxide anion generation GO:0042554 20 15 0,000 0,02072021 0,03779593 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02072021 0,0377673 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02072021 0,03773871 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02072021 0,03771016 ! copper ion transport GO:0006825 20 15 0,000 0,02072021 0,03768166 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02072021 0,0376532 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02072021 0,03762478 ! sulfate transport GO:0008272 23 15 0,000 0,02072021 0,0375964 ! response to cAMP GO:0051591 22 15 0,000 0,02072021 0,03756807 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02072021 0,03753978 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02072021 0,03751154 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02072021 0,03748333 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02072021 0,03745517 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02072021 0,03742705 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02072021 0,03739897 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02072021 0,03737094 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02072021 0,03734294 ! pituitary gland development GO:0021983 29 15 0,000 0,02072021 0,03731499 ! vesicle coating GO:0006901 33 15 0,000 0,02072021 0,03728708 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02072021 0,03725922 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02072021 0,03723139 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02072021 0,03720361 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02072021 0,03717586 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02072021 0,03714816 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02072021 0,0371205 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02072021 0,03709288 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02072021 0,0370653 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02072021 0,03703776 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02072021 0,03701027 ! histone deacetylation GO:0016575 20 15 0,000 0,02072021 0,03698281 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02072021 0,0369554 ! tissue regeneration GO:0042246 26 15 0,000 0,02072021 0,03692802 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02072021 0,03690069 ! water homeostasis GO:0030104 27 15 0,000 0,02072021 0,0368734 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02072021 0,03684614 ! muscle maintenance GO:0046716 26 15 0,000 0,02072021 0,03681893 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02072021 0,03679176 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02072021 0,03676462 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02072021 0,03673753 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02072021 0,03671048 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02072021 0,03668347 ! cell killing GO:0001906 29 15 0,000 0,02072021 0,03665649 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02072021 0,03662956 ! detection of bacterium GO:0016045 18 15 0,000 0,02072021 0,03660267 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02072021 0,03657581 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02072021 0,036549 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02072021 0,03652222 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02072021 0,03649548 ! peptide hormone processing GO:0016486 23 15 0,000 0,02072021 0,03646879 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02208656 0,03884522 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02208656 0,03881684 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02208656 0,03878851 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02208656 0,03876022 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02208656 0,03873197 ! bone remodeling GO:0046849 27 16 0,000 0,02208656 0,03870376 ! filopodium assembly GO:0046847 32 16 0,000 0,02208656 0,03867559 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02208656 0,03864746 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02208656 0,03861937 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02208656 0,03859133 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02208656 0,03856332 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02208656 0,03853536 ! startle response GO:0001964 28 16 0,000 0,02208656 0,03850743 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02208656 0,03847955 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02208656 0,03845171 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02208656 0,0384239 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02208656 0,03839614 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02208656 0,03836842 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02208656 0,03834074 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02208656 0,03831309 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02208656 0,03828549 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02208656 0,03825793 ! response to osmotic stress GO:0006970 25 16 0,000 0,02208656 0,0382304 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02208656 0,03820292 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02208656 0,03817547 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02208656 0,03814807 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02208656 0,0381207 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02208656 0,03809338 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02208656 0,03806609 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02208656 0,03803884 ! axon cargo transport GO:0008088 43 16 0,000 0,02208656 0,03801163 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02208656 0,03798446 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02208656 0,03795733 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02208656 0,03793024 ! DNA replication initiation GO:0006270 27 16 0,000 0,02208656 0,03790318 ! neuron recognition GO:0008038 35 16 0,000 0,02208656 0,03787617 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02208656 0,03784919 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02208656 0,03782225 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02208656 0,03779535 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02208656 0,03776849 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02208656 0,03774166 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02208656 0,03771488 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02208656 0,03768813 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02208656 0,03766142 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02208656 0,03763474 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02208656 0,03760811 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02208656 0,03758151 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02208656 0,03755495 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02208656 0,03752843 ! defense response to virus GO:0051607 37 16 0,000 0,02208656 0,03750195 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02345104 0,0397907 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02345104 0,03976266 ! metencephalon development GO:0022037 30 17 0,000 0,02345104 0,03973466 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02345104 0,03970669 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02345104 0,03967877 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02345104 0,03965089 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02345104 0,03962304 ! signal complex assembly GO:0007172 41 17 0,000 0,02345104 0,03959524 ! endothelial cell migration GO:0043542 28 17 0,000 0,02345104 0,03956747 ! inositol metabolic process GO:0006020 28 17 0,000 0,02345104 0,03953974 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02345104 0,03951205 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02345104 0,0394844 ! glial cell development GO:0021782 27 17 0,000 0,02345104 0,03945679 ! limbic system development GO:0021761 36 17 0,000 0,02345104 0,03942922 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02345104 0,03940168 ! adult walking behavior GO:0007628 33 17 0,000 0,02345104 0,03937419 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02345104 0,03934673 ! heart looping GO:0001947 30 17 0,000 0,02345104 0,03931931 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02345104 0,03929193 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02345104 0,03926459 ! myoblast differentiation GO:0045445 45 17 0,000 0,02345104 0,03923728 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02345104 0,03921001 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02345104 0,03918279 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02345104 0,03915559 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02345104 0,03912844 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02345104 0,03910132 ! glycine metabolic process GO:0006544 28 17 0,000 0,02345104 0,03907425 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02345104 0,0390472 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02345104 0,0390202 ! NAD metabolic process GO:0019674 29 17 0,000 0,02345104 0,03899323 ! DNA integration GO:0015074 29 17 0,000 0,02345104 0,03896631 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02345104 0,03893941 ! regulation of protein binding GO:0043393 33 17 0,000 0,02345104 0,03891256 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02345104 0,03888574 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02345104 0,03885896 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02345104 0,03883222 ! genitalia development GO:0048806 30 17 0,000 0,02345104 0,03880551 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02345104 0,03877884 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02345104 0,03875221 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02345104 0,03872561 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02345104 0,03869905 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02345104 0,03867252 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02345104 0,03864603 ! steroid catabolic process GO:0006706 31 17 0,000 0,02345104 0,03861958 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02345104 0,03859317 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02345104 0,03856679 ! gas transport GO:0015669 25 17 0,000 0,02345104 0,03854044 ! organic cation transport GO:0015695 31 17 0,000 0,02345104 0,03851414 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02345104 0,03848787 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02345104 0,03846163 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02345104 0,03843543 ! microspike assembly GO:0030035 36 17 0,000 0,02345104 0,03840927 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02345104 0,03838314 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02345104 0,03835704 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02481367 0,04055821 ! neuron maturation GO:0042551 42 18 0,000 0,02481367 0,04053068 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02481367 0,04050318 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02481367 0,04047572 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02481367 0,0404483 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02481367 0,04042091 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02481367 0,04039357 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02481367 0,04036625 ! memory GO:0007613 31 18 0,000 0,02481367 0,04033898 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02481367 0,04031174 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02481367 0,04028454 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02481367 0,04025738 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02481367 0,04023025 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02481367 0,04020316 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02481367 0,0401761 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02481367 0,04014909 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02481367 0,0401221 ! response to retinoic acid GO:0032526 26 18 0,000 0,02481367 0,04009516 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02481367 0,04006825 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02481367 0,04004137 ! response to fungus GO:0009620 21 18 0,000 0,02481367 0,04001454 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02481367 0,03998774 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02481367 0,03996097 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02481367 0,03993424 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02481367 0,03990755 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02481367 0,03988089 ! vitamin transport GO:0051180 27 18 0,000 0,02481367 0,03985427 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02481367 0,03982768 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02481367 0,03980113 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02481367 0,03977461 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02481367 0,03974813 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02481367 0,03972168 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02481367 0,03969527 ! nerve development GO:0021675 28 18 0,000 0,02481367 0,0396689 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02481367 0,03964256 ! protein secretion GO:0009306 39 19 0,000 0,02617444 0,04178879 ! positive regulation of translation GO:0045727 30 19 0,000 0,02617444 0,04176108 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02617444 0,0417334 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02617444 0,04170576 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02617444 0,04167816 ! skin development GO:0043588 36 19 0,000 0,02617444 0,0416506 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02617444 0,04162307 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02617444 0,04159558 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02617444 0,04156812 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02617444 0,0415407 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02617444 0,04151332 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02617444 0,04148597 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02617444 0,04145866 ! cerebral cortex development GO:0021987 36 19 0,000 0,02617444 0,04143138 ! pigmentation during development GO:0048066 41 19 0,000 0,02617444 0,04140414 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02617444 0,04137694 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02617444 0,04134977 ! heme metabolic process GO:0042168 36 19 0,000 0,02617444 0,04132264 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02617444 0,04129554 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02617444 0,04126848 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02617444 0,04124146 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02617444 0,04121447 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02617444 0,04118751 ! peptide cross-linking GO:0018149 37 19 0,000 0,02617444 0,04116059 ! protein export from nucleus GO:0006611 36 19 0,000 0,02617444 0,04113371 ! heart process GO:0003015 30 19 0,000 0,02617444 0,04110686 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02617444 0,04108004 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02617444 0,04105326 ! cellular pigmentation GO:0033059 36 19 0,000 0,02617444 0,04102652 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02617444 0,04099981 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02617444 0,04097313 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02617444 0,04094649 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02617444 0,04091989 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02617444 0,04089331 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02617444 0,04086678 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02617444 0,04084027 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02617444 0,04081381 ! cilium assembly GO:0042384 37 19 0,000 0,02617444 0,04078737 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02617444 0,04076097 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02753336 0,04284945 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02753336 0,04282176 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02753336 0,04279409 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02753336 0,04276647 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02753336 0,04273888 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02753336 0,04271132 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02753336 0,0426838 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02753336 0,04265631 ! response to vitamin GO:0033273 31 20 0,000 0,02753336 0,04262887 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02753336 0,04260145 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02753336 0,04257407 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02753336 0,04254673 ! response to alkaloid GO:0043279 38 20 0,000 0,02753336 0,04251942 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02753336 0,04249215 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02753336 0,04246491 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02753336 0,0424377 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02753336 0,04241054 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02753336 0,0423834 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02753336 0,0423563 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02753336 0,04232924 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02753336 0,04230221 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02753336 0,04227521 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02753336 0,04224825 ! body fluid secretion GO:0007589 31 20 0,000 0,02753336 0,04222132 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02753336 0,04219443 ! peptide secretion GO:0002790 35 20 0,000 0,02753336 0,04216757 ! stem cell differentiation GO:0048863 53 20 0,000 0,02753336 0,04214075 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02753336 0,04211396 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02753336 0,0420872 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02753336 0,04206048 ! sensory perception of pain GO:0019233 30 20 0,000 0,02753336 0,04203379 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02753336 0,04200714 ! diencephalon development GO:0021536 34 20 0,000 0,02753336 0,04198052 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02753336 0,04195393 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02753336 0,04192738 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02753336 0,04190086 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02753336 0,04187437 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02753336 0,04184792 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02753336 0,0418215 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02753336 0,04179511 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02753336 0,04176876 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02753336 0,04174244 ! regulation of glucose import GO:0046324 29 20 0,000 0,02753336 0,04171616 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02753336 0,0416899 ! actin filament-based movement GO:0030048 43 20 0,000 0,02753336 0,04166368 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02753336 0,0416375 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02753336 0,04161134 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02753336 0,04158522 ! negative regulation of translation GO:0017148 29 20 0,000 0,02753336 0,04155913 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02753336 0,04153308 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02753336 0,04150705 ! regulation of cell killing GO:0031341 42 21 0,000 0,02889042 0,04352558 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02889042 0,04349835 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02889042 0,04347114 ! hormone secretion GO:0046879 38 21 0,000 0,02889042 0,04344397 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02889042 0,04341684 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02889042 0,04338974 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02889042 0,04336267 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02889042 0,04333563 ! axis specification GO:0009798 38 21 0,000 0,02889042 0,04330863 ! ovarian follicle development GO:0001541 35 21 0,000 0,02889042 0,04328167 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02889042 0,04325473 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02889042 0,04322783 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02889042 0,04320097 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02889042 0,04317413 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02889042 0,04314733 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02889042 0,04312057 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02889042 0,04309384 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02889042 0,04306714 ! cytolysis GO:0019835 24 21 0,000 0,02889042 0,04304047 ! vasodilation GO:0042311 39 21 0,000 0,02889042 0,04301383 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02889042 0,04298723 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02889042 0,04296067 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02889042 0,04293413 ! oogenesis GO:0048477 36 21 0,000 0,02889042 0,04290763 ! DNA modification GO:0006304 34 21 0,000 0,02889042 0,04288116 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02889042 0,04285472 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02889042 0,04282832 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02889042 0,04280194 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02889042 0,0427756 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02889042 0,0427493 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02889042 0,04272302 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02889042 0,04269678 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02889042 0,04267057 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02889042 0,04264439 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02889042 0,04261824 ! collagen catabolic process GO:0030574 28 21 0,000 0,02889042 0,04259213 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02889042 0,04256605 ! gut development GO:0048565 39 21 0,000 0,02889042 0,04254 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03024564 0,04450826 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03024564 0,04448106 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03024564 0,04445388 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03024564 0,04442674 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03024564 0,04439964 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03024564 0,04437257 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03024564 0,04434553 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03024564 0,04431852 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03024564 0,04429154 ! regeneration GO:0031099 41 22 0,000 0,03024564 0,0442646 ! keratinization GO:0031424 28 22 0,000 0,03024564 0,04423769 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03024564 0,04421082 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03024564 0,04418398 ! sensory perception of taste GO:0050909 28 22 0,000 0,03024564 0,04415716 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03024564 0,04413039 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03024564 0,04410364 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03024564 0,04407693 ! vacuolar transport GO:0007034 36 22 0,000 0,03024564 0,04405025 ! lysosome organization GO:0007040 41 22 0,000 0,03024564 0,0440236 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03024564 0,04399698 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03024564 0,0439704 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03024564 0,04394385 ! fucose metabolic process GO:0006004 39 22 0,000 0,03024564 0,04391733 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03024564 0,04389084 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03024564 0,04386438 ! ureteric bud development GO:0001657 43 22 0,000 0,03024564 0,04383796 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03024564 0,04381156 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03024564 0,0437852 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03024564 0,04375887 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,03024564 0,04373258 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03024564 0,04370631 ! sarcomere organization GO:0045214 30 22 0,000 0,03024564 0,04368008 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03024564 0,04365387 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03024564 0,0436277 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03024564 0,04360156 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03024564 0,04357545 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03024564 0,04354938 ! protein stabilization GO:0050821 39 22 0,000 0,03024564 0,04352333 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03159901 0,04544364 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03159901 0,0454165 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03159901 0,04538938 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03159901 0,0453623 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03159901 0,04533525 ! gluconeogenesis GO:0006094 33 23 0,000 0,03159901 0,04530823 ! viral genome replication GO:0019079 41 23 0,000 0,03159901 0,04528125 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03159901 0,0452543 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03159901 0,04522737 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03159901 0,04520049 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03159901 0,04517363 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03159901 0,0451468 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03159901 0,04512001 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03159901 0,04509325 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03159901 0,04506652 ! response to ethanol GO:0045471 46 23 0,000 0,03159901 0,04503982 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03159901 0,04501315 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03159901 0,04498652 ! peroxisome organization GO:0007031 37 23 0,000 0,03159901 0,04495992 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03159901 0,04493334 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03159901 0,0449068 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03159901 0,04488029 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03159901 0,04485382 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03159901 0,04482737 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03159901 0,04480095 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03159901 0,04477457 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03159901 0,04474821 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03159901 0,04472189 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03159901 0,0446956 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03159901 0,04466934 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03159901 0,04464311 ! fatty acid transport GO:0015908 44 23 0,000 0,03159901 0,04461691 ! platelet activation GO:0030168 37 23 0,000 0,03159901 0,04459074 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03159901 0,04456461 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03159901 0,0445385 ! hormone transport GO:0009914 40 23 0,000 0,03159901 0,04451242 ! cell-cell recognition GO:0009988 25 23 0,000 0,03159901 0,04448638 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03159901 0,04446036 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03159901 0,04443438 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03159901 0,04440842 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03159901 0,0443825 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03159901 0,0443566 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03295054 0,04622682 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03295054 0,04619988 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03295054 0,04617297 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03295054 0,04614609 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03295054 0,04611925 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03295054 0,04609244 ! vesicle docking GO:0048278 47 24 0,000 0,03295054 0,04606565 ! spinal cord development GO:0021510 47 24 0,000 0,03295054 0,0460389 ! vacuole organization GO:0007033 43 24 0,000 0,03295054 0,04601218 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03295054 0,04598549 ! digestive system process GO:0022600 39 24 0,000 0,03295054 0,04595883 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03295054 0,04593221 ! regulation of behavior GO:0050795 43 24 0,000 0,03295054 0,04590561 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03295054 0,04587905 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03295054 0,04585251 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03295054 0,04582601 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03295054 0,04579953 ! membrane depolarization GO:0051899 39 24 0,000 0,03295054 0,04577309 ! pallium development GO:0021543 49 24 0,000 0,03295054 0,04574668 ! pentose metabolic process GO:0019321 35 24 0,000 0,03295054 0,04572029 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03295054 0,04569394 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03295054 0,04566762 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03295054 0,04564133 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03295054 0,04561507 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03295054 0,04558884 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03295054 0,04556264 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03295054 0,04553647 ! regulation of amine transport GO:0051952 40 24 0,000 0,03295054 0,04551033 ! protein tetramerization GO:0051262 52 24 0,000 0,03295054 0,04548422 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03430022 0,04732014 ! myelination GO:0042552 45 25 0,000 0,03430022 0,04729303 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03430022 0,04726594 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03430022 0,04723889 ! phototransduction GO:0007602 33 25 0,000 0,03430022 0,04721186 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03430022 0,04718487 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03430022 0,0471579 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03430022 0,04713097 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03430022 0,04710407 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03430022 0,0470772 ! receptor metabolic process GO:0043112 46 25 0,000 0,03430022 0,04705036 ! chromosome condensation GO:0030261 45 25 0,000 0,03430022 0,04702355 ! response to starvation GO:0042594 42 25 0,000 0,03430022 0,04699677 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03430022 0,04697002 ! neural crest cell development GO:0014032 54 25 0,000 0,03430022 0,04694331 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03430022 0,04691662 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03430022 0,04688996 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03430022 0,04686333 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03430022 0,04683674 ! interaction with host GO:0051701 62 25 0,000 0,03430022 0,04681017 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03430022 0,04678364 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03430022 0,04675713 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03430022 0,04673065 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03430022 0,04670421 ! immunoglobulin production GO:0002377 55 25 0,000 0,03430022 0,04667779 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03430022 0,0466514 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03430022 0,04662505 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03430022 0,04659872 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03430022 0,04657242 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03430022 0,04654615 ! telomere organization GO:0032200 43 25 0,000 0,03430022 0,04651992 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03430022 0,04649371 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03430022 0,04646753 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03564807 0,04826632 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03564807 0,04823917 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03564807 0,04821206 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03564807 0,04818497 ! initiation of viral infection GO:0019059 57 26 0,000 0,03564807 0,04815792 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03564807 0,04813089 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03564807 0,0481039 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03564807 0,04807693 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03564807 0,04805 ! molting cycle process GO:0022404 50 26 0,000 0,03564807 0,0480231 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03564807 0,04799622 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03564807 0,04796938 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03564807 0,04794257 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03564807 0,04791578 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03564807 0,04788903 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03564807 0,04786231 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03564807 0,04783561 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03564807 0,04780895 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03564807 0,04778231 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03564807 0,04775571 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03564807 0,04772913 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03564807 0,04770259 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03564807 0,04767607 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03564807 0,04764958 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03564807 0,04762313 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03564807 0,0475967 ! blastocyst development GO:0001824 49 26 0,000 0,03564807 0,0475703 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03564807 0,04754393 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03564807 0,04751759 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03564807 0,04749128 ! neuron fate commitment GO:0048663 48 27 0,000 0,03699408 0,04925719 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03699408 0,04922995 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03699408 0,04920274 ! iron ion transport GO:0006826 59 27 0,000 0,03699408 0,04917555 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03699408 0,0491484 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03699408 0,04912128 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03699408 0,04909418 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03699408 0,04906712 ! fat cell differentiation GO:0045444 50 27 0,000 0,03699408 0,04904008 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03699408 0,04901308 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03699408 0,0489861 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03699408 0,04895916 ! autophagy GO:0006914 41 27 0,000 0,03699408 0,04893224 ! male gonad development GO:0008584 44 27 0,000 0,03699408 0,04890536 ! response to toxin GO:0009636 47 27 0,000 0,03699408 0,0488785 ! primary neural tube formation GO:0014020 51 27 0,000 0,03699408 0,04885167 ! base-excision repair GO:0006284 41 27 0,000 0,03699408 0,04882488 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03699408 0,04879811 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03699408 0,04877137 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03699408 0,04874466 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03699408 0,04871798 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03699408 0,04869133 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03699408 0,04866471 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03699408 0,04863812 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03699408 0,04861155 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03833825 0,05035035 ! circadian rhythm GO:0007623 50 28 0,000 0,03833825 0,05032288 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03833825 0,05029544 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03833825 0,05026803 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03833825 0,05024065 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03833825 0,0502133 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,03833825 0,05018598 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03833825 0,05015869 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03833825 0,05013143 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03833825 0,0501042 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03833825 0,050077 ! synaptogenesis GO:0007416 42 28 0,000 0,03833825 0,05004983 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03833825 0,05002269 ! lipid oxidation GO:0034440 43 28 0,000 0,03833825 0,04999558 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03833825 0,04996849 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03833825 0,04994144 ! translational initiation GO:0006413 65 29 0,000 0,0396806 0,05166208 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0396806 0,05163414 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0396806 0,05160623 ! regulation of pH GO:0006885 43 29 0,000 0,0396806 0,05157835 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0396806 0,0515505 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0396806 0,05152268 ! catechol metabolic process GO:0009712 54 29 0,000 0,0396806 0,05149489 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0396806 0,05146713 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0396806 0,0514394 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0396806 0,05141169 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0396806 0,05138402 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0396806 0,05135638 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0396806 0,05132877 ! cell fate determination GO:0001709 60 29 0,000 0,0396806 0,05130119 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0396806 0,05127364 ! detection of light stimulus GO:0009583 38 29 0,000 0,0396806 0,05124612 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0396806 0,05121863 ! tissue homeostasis GO:0001894 48 29 0,000 0,0396806 0,05119116 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0396806 0,05116373 ! phenol metabolic process GO:0018958 55 30 0,000 0,04102111 0,05286384 ! zinc ion transport GO:0006829 45 30 0,000 0,04102111 0,05283554 ! membrane docking GO:0022406 61 30 0,000 0,04102111 0,05280727 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04102111 0,05277904 ! cell junction assembly GO:0034329 78 30 0,000 0,04102111 0,05275083 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04102111 0,05272265 ! acute-phase response GO:0006953 49 30 0,000 0,04102111 0,0526945 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04102111 0,05266638 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04102111 0,05263829 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04102111 0,05261023 ! phospholipid transport GO:0015914 51 30 0,000 0,04102111 0,0525822 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04102111 0,0525542 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04102111 0,05252624 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04102111 0,0524983 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04102111 0,05247039 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04102111 0,05244251 ! response to heat GO:0009408 50 30 0,000 0,04102111 0,05241466 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,0423598 0,05409643 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,0423598 0,05406773 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,0423598 0,05403907 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,0423598 0,05401043 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,0423598 0,05398182 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,0423598 0,05395325 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,0423598 0,0539247 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,0423598 0,05389618 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,0423598 0,0538677 ! ovulation cycle process GO:0022602 49 31 0,000 0,0423598 0,05383924 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,0423598 0,05381081 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,0423598 0,05378242 ! peptide transport GO:0015833 55 31 0,000 0,0423598 0,05375405 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,0423598 0,05372571 ! iron ion homeostasis GO:0055072 54 31 0,000 0,0423598 0,05369741 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,0423598 0,05366913 ! mesoderm formation GO:0001707 69 31 0,000 0,0423598 0,05364088 ! natural killer cell activation GO:0030101 45 31 0,000 0,0423598 0,05361267 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,0423598 0,05358448 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,0423598 0,05355632 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,0423598 0,05352819 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,0423598 0,05350009 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,0423598 0,05347203 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04369666 0,05513066 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04369666 0,05510177 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04369666 0,0550729 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04369666 0,05504407 ! cholesterol transport GO:0030301 56 32 0,000 0,04369666 0,05501527 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04369666 0,05498649 ! spliceosome assembly GO:0000245 67 32 0,000 0,04369666 0,05495775 ! spindle organization GO:0007051 46 32 0,000 0,04369666 0,05492904 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04369666 0,05490035 ! metanephros development GO:0001656 74 32 0,000 0,04369666 0,0548717 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04369666 0,05484308 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04369666 0,05481448 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04369666 0,05478592 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04369666 0,05475738 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04369666 0,05472888 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04369666 0,0547004 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04369666 0,05467196 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04369666 0,05464354 ! ovulation cycle GO:0042698 51 32 0,000 0,04369666 0,05461516 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04369666 0,0545868 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04369666 0,05455847 ! hindbrain development GO:0030902 61 32 0,000 0,04369666 0,05453017 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04369666 0,05450191 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04369666 0,05447367 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04369666 0,05444546 ! gene silencing GO:0016458 65 32 0,000 0,04369666 0,05441727 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04503171 0,05605085 ! post-embryonic development GO:0009791 69 33 0,000 0,04503171 0,05602186 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04503171 0,05599291 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04503171 0,05596399 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04503171 0,0559351 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04503171 0,05590624 ! cell fate specification GO:0001708 52 33 0,000 0,04503171 0,0558774 ! sterol transport GO:0015918 57 33 0,000 0,04503171 0,0558486 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04503171 0,05581983 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04503171 0,05579108 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04503171 0,05576237 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04503171 0,05573369 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04503171 0,05570503 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04636493 0,05732478 ! glial cell differentiation GO:0010001 63 34 0,000 0,04636493 0,05729534 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04636493 0,05726592 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04636493 0,05723654 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04636493 0,05720719 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04636493 0,05717787 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04636493 0,05714858 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04636493 0,05711931 ! mismatch repair GO:0006298 46 34 0,000 0,04636493 0,05709008 ! spermatid development GO:0007286 63 34 0,000 0,04636493 0,05706088 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04636493 0,05703171 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04636493 0,05700257 ! placenta development GO:0001890 53 34 0,000 0,04636493 0,05697345 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04636493 0,05694437 ! regulation of muscle development GO:0048634 70 35 0,000 0,04769633 0,05854968 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04769633 0,05851983 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04769633 0,05849 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04769633 0,0584602 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04769633 0,05843044 ! odontogenesis GO:0042476 66 35 0,000 0,04769633 0,0584007 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04769633 0,058371 ! female gonad development GO:0008585 58 35 0,000 0,04769633 0,05834132 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04769633 0,05831168 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04769633 0,05828206 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04769633 0,05825248 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04769633 0,05822292 ! cytokine production GO:0001816 59 35 0,000 0,04769633 0,0581934 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,04769633 0,0581639 ! neural tube formation GO:0001841 67 35 0,000 0,04769633 0,05813444 ! vesicle localization GO:0051648 64 35 0,000 0,04769633 0,058105 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04902593 0,05969452 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04902593 0,05966433 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,04902593 0,05963416 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,04902593 0,05960403 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04902593 0,05957393 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04902593 0,05954386 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04902593 0,05951381 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04902593 0,0594838 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04902593 0,05945382 ! aerobic respiration GO:0009060 55 36 0,000 0,04902593 0,05942387 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,04902593 0,05939395 ! embryonic organ development GO:0048568 57 36 0,000 0,04902593 0,05936406 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04902593 0,05933419 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0503537 0,06091051 ! meiosis I GO:0007127 65 37 0,000 0,0503537 0,06087991 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0503537 0,06084933 ! organic anion transport GO:0015711 68 37 0,000 0,0503537 0,06081878 ! tissue remodeling GO:0048771 76 37 0,000 0,0503537 0,06078827 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0503537 0,06075778 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0503537 0,06072732 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,0503537 0,0606969 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0503537 0,06066651 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0503537 0,06063614 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0503537 0,06060581 ! glycogen metabolic process GO:0005977 61 37 0,000 0,0503537 0,06057551 ! pigment metabolic process GO:0042440 80 37 0,000 0,0503537 0,06054523 ! spermatid differentiation GO:0048515 66 37 0,000 0,0503537 0,06051499 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,05167967 0,06207753 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,05167967 0,06204655 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05167967 0,06201561 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05167967 0,06198469 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05167967 0,06195381 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,05167967 0,06192296 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,05167967 0,06189213 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05167967 0,06186134 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05167967 0,06183058 ! lipid homeostasis GO:0055088 67 38 0,000 0,05167967 0,06179985 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05167967 0,06176915 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,05167967 0,06173848 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05167967 0,06170784 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05167967 0,06167723 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05167967 0,06164665 ! glucan metabolic process GO:0044042 62 38 0,000 0,05167967 0,0616161 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,05300383 0,06316356 ! mammary gland development GO:0030879 86 39 0,000 0,05300383 0,06313229 ! ear morphogenesis GO:0042471 60 39 0,000 0,05300383 0,06310105 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05300383 0,06306984 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05300383 0,06303867 ! segmentation GO:0035282 67 39 0,000 0,05300383 0,06300752 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05300383 0,06297641 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05300383 0,06294532 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05300383 0,06291427 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05300383 0,06288325 ! RNA modification GO:0009451 57 39 0,000 0,05300383 0,06285226 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05300383 0,06282129 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05432619 0,06435688 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05432619 0,0643252 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05432619 0,06429356 ! feeding behavior GO:0007631 59 40 0,000 0,05432619 0,06426195 ! negative regulation of binding GO:0051100 72 40 0,000 0,05432619 0,06423038 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05432619 0,06419883 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05432619 0,06416731 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05432619 0,06413583 ! maintenance of protein location GO:0045185 91 40 0,000 0,05432619 0,06410437 ! cytokinesis GO:0000910 72 40 0,000 0,05432619 0,06407295 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,05564675 0,06559827 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,05564675 0,06556615 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,05564675 0,06553405 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,05564675 0,06550199 ! gliogenesis GO:0042063 88 41 0,000 0,05564675 0,06546996 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,05564675 0,06543796 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,05564675 0,06540599 ! T cell differentiation GO:0030217 81 41 0,000 0,05564675 0,06537406 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,05564675 0,06534215 ! female gamete generation GO:0007292 61 41 0,000 0,05564675 0,06531028 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,05564675 0,06527843 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0569655 0,06679288 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0569655 0,06676035 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,0569655 0,06672784 ! regulation of tube size GO:0035150 71 42 0,000 0,0569655 0,06669537 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0569655 0,06666293 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0569655 0,06663053 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,0569655 0,06659815 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0569655 0,0665658 ! neuron migration GO:0001764 79 42 0,000 0,0569655 0,06653349 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0569655 0,06650121 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0569655 0,06646896 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05828245 0,06797265 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05828245 0,06793972 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05828245 0,06790682 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05828245 0,06787395 ! glucose transport GO:0015758 65 43 0,000 0,05828245 0,06784112 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05828245 0,06780831 ! neural tube development GO:0021915 77 43 0,000 0,05828245 0,06777554 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05828245 0,0677428 ! striated muscle contraction GO:0006941 77 43 0,000 0,05828245 0,06771009 ! phagocytosis GO:0006909 90 43 0,000 0,05828245 0,06767741 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05828245 0,06764476 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05959762 0,06913783 ! hexose transport GO:0008645 67 44 0,000 0,05959762 0,06910451 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05959762 0,06907122 ! male sex differentiation GO:0046661 76 44 0,000 0,05959762 0,06903797 ! double-strand break repair GO:0006302 81 44 0,000 0,05959762 0,06900475 ! biopolymer methylation GO:0043414 84 44 0,000 0,05959762 0,06897155 ! B cell differentiation GO:0030183 107 44 0,000 0,05959762 0,0689384 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05959762 0,06890527 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05959762 0,06887217 ! developmental growth GO:0048589 82 44 0,000 0,05959762 0,06883911 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05959762 0,06880608 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06091098 0,07028864 ! glycolysis GO:0006096 65 45 0,000 0,06091098 0,07025495 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,06091098 0,07022129 ! leukocyte migration GO:0050900 68 45 0,000 0,06091098 0,07018766 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06091098 0,07015406 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,06091098 0,07012049 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06091098 0,07008696 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,06091098 0,07005345 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06091098 0,07001998 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06091098 0,06998654 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06091098 0,06995314 ! cell growth GO:0016049 84 45 0,000 0,06091098 0,06991976 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06222256 0,07139126 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,06222256 0,07135723 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,06222256 0,07132324 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06222256 0,07128928 ! pigmentation GO:0043473 100 46 0,000 0,06222256 0,07125534 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,06222256 0,07122145 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06353235 0,07268608 ! response to calcium ion GO:0051592 81 47 0,000 0,06353235 0,07265154 ! endosome transport GO:0016197 108 47 0,000 0,06353235 0,07261702 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06353235 0,07258254 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06353235 0,07254809 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06353235 0,07251368 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06353235 0,07247929 ! JNK cascade GO:0007254 91 47 0,000 0,06353235 0,07244494 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06353235 0,07241063 ! methylation GO:0032259 90 47 0,000 0,06353235 0,07237634 ! protein homooligomerization GO:0051260 76 47 0,000 0,06353235 0,07234209 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,06484035 0,07379654 ! mitochondrial transport GO:0006839 82 48 0,000 0,06484035 0,07376165 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06484035 0,07372679 ! cellular component disassembly GO:0022411 86 48 0,000 0,06484035 0,07369196 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06484035 0,07365717 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,06484035 0,07362241 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06484035 0,07358768 ! activation of caspase activity GO:0006919 84 48 0,000 0,06484035 0,07355299 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06484035 0,07351832 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06484035 0,07348369 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06484035 0,0734491 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06614657 0,07489348 ! regulation of action potential GO:0001508 95 49 0,000 0,06614657 0,07485825 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06614657 0,07482306 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06614657 0,0747879 ! regulation of ion transport GO:0043269 77 49 0,000 0,06614657 0,07475277 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06614657 0,07471768 ! peptide metabolic process GO:0006518 76 49 0,000 0,06614657 0,07468261 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06614657 0,07464758 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06614657 0,07461259 ! endocrine system development GO:0035270 104 49 0,000 0,06614657 0,07457762 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06614657 0,07454269 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06614657 0,07450779 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06614657 0,07447293 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,06745101 0,07590605 ! neuromuscular process GO:0050905 99 50 0,000 0,06745101 0,07587056 ! regulation of ossification GO:0030278 117 50 0,000 0,06745101 0,07583511 ! inner ear development GO:0048839 79 50 0,000 0,06745101 0,07579969 ! histone modification GO:0016570 91 50 0,000 0,06745101 0,0757643 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06745101 0,07572894 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06745101 0,07569362 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06745101 0,07565833 ! positive regulation of binding GO:0051099 78 51 0,000 0,06875367 0,07708356 ! viral infectious cycle GO:0019058 99 51 0,000 0,06875367 0,07704766 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06875367 0,07701179 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06875367 0,07697595 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06875367 0,07694015 ! excretion GO:0007588 83 51 0,000 0,06875367 0,07690438 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06875367 0,07686865 ! chromatin remodeling GO:0006338 109 51 0,000 0,06875367 0,07683294 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06875367 0,07679727 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06875367 0,07676164 ! regulation of cell shape GO:0008360 125 51 0,000 0,06875367 0,07672603 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06875367 0,07669046 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,07005455 0,07810531 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,07005455 0,07806913 ! membrane fusion GO:0006944 110 52 0,000 0,07005455 0,07803299 ! positive regulation of growth GO:0045927 90 52 0,000 0,07005455 0,07799688 ! covalent chromatin modification GO:0016569 101 52 0,000 0,07005455 0,0779608 ! amino acid activation GO:0043038 92 52 0,000 0,07005455 0,07792476 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,07005455 0,07788875 ! synapse organization GO:0050808 85 52 0,000 0,07005455 0,07785277 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,07135366 0,07925988 ! RNA catabolic process GO:0006401 93 53 0,000 0,07135366 0,07922331 ! regulation of translational initiation GO:0006446 82 53 0,000 0,07135366 0,07918676 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,07135366 0,07915026 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,07135366 0,07911378 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,07135366 0,07907734 ! cell maturation GO:0048469 100 53 0,000 0,07135366 0,07904093 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,07135366 0,07900456 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,072651 0,080404 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,072651 0,08036703 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,072651 0,0803301 ! cell recognition GO:0008037 85 54 0,000 0,072651 0,0802932 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,072651 0,08025634 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,072651 0,0802195 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,072651 0,08018271 ! chloride transport GO:0006821 90 55 0,000 0,07394656 0,08157516 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07394656 0,08153778 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,07394656 0,08150043 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,07394656 0,08146311 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07394656 0,08142583 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07394656 0,08138858 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,07394656 0,08135136 ! gastrulation GO:0007369 112 55 0,000 0,07394656 0,08131418 ! heart morphogenesis GO:0003007 97 55 0,000 0,07394656 0,08127704 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,07394656 0,08123992 ! RNA elongation GO:0006354 79 55 0,000 0,07394656 0,08120285 ! nuclear export GO:0051168 97 55 0,000 0,07394656 0,0811658 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07394656 0,08112879 ! regulation of actin filament length GO:0030832 105 56 0,000 0,07524037 0,08251063 ! sensory perception of smell GO:0007608 80 56 0,000 0,07524037 0,08247304 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07524037 0,08243548 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07524037 0,08239796 ! regulation of DNA replication GO:0006275 101 56 0,000 0,07524037 0,08236047 ! proton transport GO:0015992 94 56 0,000 0,07524037 0,08232302 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,07524037 0,0822856 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,0765324 0,08366059 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,0765324 0,0836226 ! lipid modification GO:0030258 97 57 0,000 0,0765324 0,08358464 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,0765324 0,08354671 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,0765324 0,08350882 ! maintenance of location GO:0051235 118 57 0,000 0,0765324 0,08347097 ! hydrogen transport GO:0006818 97 58 0,000 0,07782268 0,08483976 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,07782268 0,08480134 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07782268 0,08476295 ! adult behavior GO:0030534 99 58 0,000 0,07782268 0,0847246 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07782268 0,08468628 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07911119 0,08604951 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07911119 0,08601063 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07911119 0,08597178 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07911119 0,08593297 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07911119 0,08589419 ! DNA catabolic process GO:0006308 86 59 0,000 0,07911119 0,08585545 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07911119 0,08581674 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07911119 0,08577806 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,08039795 0,08713399 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,08039795 0,08709476 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,08039795 0,08705556 ! regulation of heart contraction GO:0008016 110 60 0,000 0,08039795 0,0870164 ! camera-type eye development GO:0043010 116 60 0,000 0,08039795 0,08697728 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,08039795 0,08693818 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,08039795 0,08689913 ! kidney development GO:0001822 122 60 0,000 0,08039795 0,08686011 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,08168295 0,08820879 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,08168295 0,08816921 ! mesoderm development GO:0007498 119 61 0,000 0,08168295 0,08812967 ! tRNA processing GO:0008033 89 61 0,000 0,08168295 0,08809017 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,08168295 0,0880507 ! ear development GO:0043583 103 62 0,000 0,0829662 0,08939394 ! viral reproductive process GO:0022415 126 62 0,000 0,0829662 0,08935393 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,0829662 0,08931395 ! gonad development GO:0008406 98 62 0,000 0,0829662 0,089274 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,0829662 0,08923409 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08424769 0,09057192 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,08424769 0,09053147 ! detection of external stimulus GO:0009581 91 63 0,000 0,08424769 0,09049105 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08424769 0,09045067 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,08424769 0,09041033 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08552744 0,09174277 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08552744 0,09170189 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,08552744 0,09166104 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08552744 0,09162023 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08552744 0,09157945 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,08552744 0,09153871 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,08680545 0,09286523 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,08680545 0,09282396 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,08680545 0,09278272 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,08680545 0,09274152 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,08680545 0,09270036 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08808171 0,09402156 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08808171 0,09397986 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08808171 0,0939382 ! secondary metabolic process GO:0019748 116 66 0,000 0,08808171 0,09389658 ! developmental maturation GO:0021700 116 66 0,000 0,08808171 0,093855 ! cell projection assembly GO:0030031 120 66 0,000 0,08808171 0,09381345 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,08935623 0,0951288 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08935623 0,09508672 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08935623 0,09504469 ! lung development GO:0030324 144 67 0,000 0,08935623 0,09500269 ! chromosome segregation GO:0007059 113 67 0,000 0,08935623 0,09496073 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08935623 0,0949188 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08935623 0,09487691 ! hexose catabolic process GO:0019320 104 67 0,000 0,08935623 0,09483506 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,08935623 0,09479325 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08935623 0,09475147 ! adaptive immune response GO:0002250 119 67 0,000 0,08935623 0,09470973 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08935623 0,09466802 ! amino acid transport GO:0006865 125 68 0,000 0,09062901 0,0959742 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,09062901 0,09593198 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,09062901 0,09588979 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,09062901 0,09584764 ! viral reproduction GO:0016032 134 68 0,000 0,09062901 0,09580553 ! regulation of lipase activity GO:0060191 130 68 0,000 0,09062901 0,09576346 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,09062901 0,09572142 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,09190005 0,09702129 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,09190005 0,09697874 ! urogenital system development GO:0001655 137 69 0,000 0,09190005 0,09693622 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,09190005 0,09689374 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,09190005 0,0968513 ! antigen processing and presentation GO:0019882 104 69 0,000 0,09190005 0,0968089 ! appendage morphogenesis GO:0035107 135 70 0,000 0,09316936 0,09810305 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,09316936 0,09806014 ! amine catabolic process GO:0009310 117 71 0,000 0,09443694 0,0993508 ! reproductive structure development GO:0048608 113 71 0,000 0,09443694 0,09930737 ! appendage development GO:0048736 136 71 0,000 0,09443694 0,09926399 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,09443694 0,09922064 ! B cell activation GO:0042113 160 71 0,000 0,09443694 0,09917733 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,09443694 0,09913406 ! regulation of immune effector process GO:0002697 137 71 0,000 0,09443694 0,09909083 ! acute inflammatory response GO:0002526 113 72 0,000 0,09570278 0,10037528 ! regulation of caspase activity GO:0043281 122 72 0,000 0,09570278 0,10033155 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,09570278 0,10028785 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,09570278 0,10024419 ! carbohydrate transport GO:0008643 110 72 0,000 0,09570278 0,10020056 ! respiratory system development GO:0060541 153 72 0,000 0,09570278 0,10015698 ! regulation of blood pressure GO:0008217 125 73 0,000 0,0969669 0,10143581 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,0969669 0,10139173 ! axon guidance GO:0007411 139 73 0,000 0,0969669 0,10134768 ! fertilization GO:0009566 90 73 0,000 0,0969669 0,10130368 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,0982293 0,10257799 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,0982293 0,10253349 ! neurotransmitter transport GO:0006836 123 74 0,000 0,0982293 0,10248903 ! meiosis GO:0007126 121 74 0,000 0,0982293 0,1024446 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,0982293 0,10240021 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,0982293 0,10235586 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,0982293 0,10231156 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,0982293 0,10226728 ! organelle localization GO:0051640 136 74 0,000 0,0982293 0,10222305 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,09948997 0,10349022 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,09948997 0,10344549 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,09948997 0,10340081 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,09948997 0,10335616 ! meiotic cell cycle GO:0051321 122 75 0,000 0,09948997 0,10331155 ! rhythmic process GO:0048511 128 75 0,000 0,09948997 0,10326698 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,09948997 0,10322245 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,10074892 0,10448358 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,10074892 0,10443856 ! defense response to bacterium GO:0042742 89 76 0,000 0,10074892 0,10439359 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,10074892 0,10434865 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,10074892 0,10430375 ! regulation of catabolic process GO:0009894 161 76 0,000 0,10074892 0,10425888 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,10200616 0,10551454 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,10200616 0,10546919 ! blood coagulation GO:0007596 146 78 0,000 0,10326167 0,10672147 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,10326167 0,10667565 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,10326167 0,10662986 ! protein oligomerization GO:0051259 139 78 0,000 0,10326167 0,10658412 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,10451548 0,10783201 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,10451548 0,10778578 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,10451548 0,1077396 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,10451548 0,10769346 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,10451548 0,10764736 ! response to metal ion GO:0010038 140 80 0,000 0,10576757 0,10889036 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,10576757 0,10884379 ! protein import into nucleus GO:0006606 158 80 0,000 0,10576757 0,10879725 ! inorganic anion transport GO:0015698 138 80 0,000 0,10576757 0,10875076 ! T cell activation GO:0042110 168 81 0,000 0,10701795 0,1099894 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,10701795 0,10994244 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,10701795 0,10989552 ! digestion GO:0007586 112 81 0,000 0,10701795 0,10984863 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,10701795 0,10980179 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,10701795 0,10975498 ! nuclear import GO:0051170 161 81 0,000 0,10701795 0,10970822 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,10701795 0,1096615 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,10826663 0,11089379 ! response to drug GO:0042493 143 82 0,000 0,10826663 0,1108466 ! response to nutrient GO:0007584 125 82 0,000 0,10826663 0,11079945 ! response to oxygen levels GO:0070482 176 83 0,000 0,1095136 0,11202794 ! hemostasis GO:0007599 158 84 0,000 0,11075887 0,11325365 ! negative regulation of transport GO:0051051 153 84 0,000 0,11075887 0,11320554 ! response to unfolded protein GO:0006986 131 85 0,000 0,11200244 0,11442797 ! nucleosome assembly GO:0006334 122 85 0,000 0,11200244 0,1143794 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,11200244 0,11433087 ! amine biosynthetic process GO:0009309 138 86 0,000 0,11324431 0,11554954 ! response to inorganic substance GO:0010035 153 86 0,000 0,11324431 0,11550056 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,11324431 0,11545162 ! chromatin assembly GO:0031497 124 86 0,000 0,11324431 0,11540272 ! tube morphogenesis GO:0035239 176 86 0,000 0,11324431 0,11535386 ! mitochondrion organization GO:0007005 148 86 0,000 0,11324431 0,11530504 ! amine transport GO:0015837 155 86 0,000 0,11324431 0,11525627 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,11448449 0,11646921 ! protein localization in nucleus GO:0034504 176 87 0,000 0,11448449 0,11641998 ! regulation of protein transport GO:0051223 154 87 0,000 0,11448449 0,1163708 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,11572297 0,11758001 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,11572297 0,11753038 ! regulation of DNA binding GO:0051101 155 88 0,000 0,11572297 0,11748079 ! gland development GO:0048732 206 88 0,000 0,11572297 0,11743124 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,11572297 0,11738173 ! cellular defense response GO:0006968 114 89 0,000 0,11695976 0,11858626 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,11695976 0,11853631 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,11695976 0,1184864 ! sex differentiation GO:0007548 145 90 0,000 0,11819487 0,11968723 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11819487 0,11963687 ! sterol metabolic process GO:0016125 152 91 0,000 0,11942828 0,1208345 ! response to protein stimulus GO:0051789 149 91 0,000 0,11942828 0,12078371 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11942828 0,12073296 ! regulation of defense response GO:0031347 149 92 0,000 0,12066002 0,12192692 ! nucleosome organization GO:0034728 138 92 0,000 0,12066002 0,12187574 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,12066002 0,12182459 ! vitamin metabolic process GO:0006766 139 92 0,000 0,12066002 0,12177349 ! regulation of membrane potential GO:0042391 164 93 0,000 0,12189007 0,12296331 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,12189007 0,12291178 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,12311844 0,12409844 ! female pregnancy GO:0007565 164 94 0,000 0,12311844 0,12404647 ! transcription initiation GO:0006352 153 94 0,000 0,12311844 0,12399454 ! regulation of T cell activation GO:0050863 158 94 0,000 0,12311844 0,12394266 ! forebrain development GO:0030900 188 95 0,000 0,12434513 0,12512522 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,12434513 0,12507291 ! leukocyte differentiation GO:0002521 202 96 0,000 0,12557015 0,12625231 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,12557015 0,12619958 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,12557015 0,12614688 ! positive regulation of immune response GO:0050778 156 96 0,000 0,12557015 0,12609423 ! detection of stimulus GO:0051606 151 96 0,000 0,12557015 0,12604163 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,1267935 0,12721649 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,1267935 0,12716347 ! protein ubiquitination GO:0016567 217 97 0,000 0,1267935 0,12711048 ! hormone metabolic process GO:0042445 157 97 0,000 0,1267935 0,12705754 ! regulation of protein localization GO:0032880 176 97 0,000 0,1267935 0,12700464 ! response to virus GO:0009615 160 98 0,000 0,12801517 0,12817499 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,12801517 0,12812167 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,12801517 0,1280684 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12923518 0,12923518