pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/11143-0-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 4,833E-07 8,907E-04 ! regulation of chromosome organization GO:0033044 12 12 2,000 8,843E-07 8,148E-04 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 2,000 1,148E-06 7,055E-04 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 1,148E-06 5,291E-04 ! negative regulation of protein transport GO:0051224 21 21 2,000 5,299E-06 1,953E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 2,000 6,129E-06 1,883E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 9,127E-06 2,403E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,158E-05 2,669E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,773E-05 3,631E-03 ! muscle cell migration GO:0014812 5 5 1,000 2,781E-05 5,125E-03 ! lysogeny GO:0030069 5 5 1,000 2,781E-05 4,659E-03 GO:0019047|provirus integration, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 4,167E-05 6,4E-03 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 1,000 4,167E-05 5,908E-03 ! DNA unwinding during replication GO:0006268 6 6 1,000 4,167E-05 5,486E-03 ! protein sumoylation GO:0016925 6 6 1,000 4,167E-05 5,12E-03 ! thymus development GO:0048538 6 6 1,000 4,167E-05 4,8E-03 ! negative regulation of organelle organization GO:0010639 45 44 2,000 5,158E-05 5,592E-03 ! axis specification GO:0009798 7 7 1,000 5,829E-05 5,968E-03 ! regulation of mRNA processing GO:0050684 7 7 1,000 5,829E-05 5,654E-03 ! DNA integration GO:0015074 7 7 1,000 5,829E-05 5,371E-03 ! induction of an organ GO:0001759 7 7 1,000 5,829E-05 5,115E-03 ! negative regulation of transport GO:0051051 51 50 2,000 7,589E-05 6,358E-03 ! thyroid gland development GO:0030878 8 8 1,000 7,764E-05 6,221E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 7,764E-05 5,962E-03 ! DNA duplex unwinding GO:0032508 8 8 1,000 7,764E-05 5,724E-03 GO:0032392|DNA geometric change, ! developmental induction GO:0031128 8 8 1,000 7,764E-05 5,504E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 7,764E-05 5,3E-03 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 8,055E-05 5,302E-03 ! regulation of protein transport GO:0051223 53 53 2,000 9,044E-05 5,747E-03 GO:0070201|regulation of establishment of protein localization, ! negative regulation of cell cycle process GO:0010948 9 9 1,000 9,973E-05 6,127E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 9,973E-05 5,929E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 9,973E-05 5,744E-03 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 1,011E-04 5,645E-03 ! regulation of protein localization GO:0032880 58 57 2,000 1,125E-04 6,099E-03 ! histone deacetylation GO:0016575 10 10 1,000 1,245E-04 6,558E-03 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 1,518E-04 7,771E-03 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 1,521E-04 7,575E-03 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,823E-04 8,842E-03 ! initiation of viral infection GO:0019059 12 12 1,000 1,823E-04 8,615E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,823E-04 8,4E-03 ! ureteric bud development GO:0001657 13 13 1,000 2,152E-04 9,675E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 2,152E-04 9,445E-03 ! activation of JUN kinase activity GO:0007257 13 13 1,000 2,152E-04 9,225E-03 ! tissue homeostasis GO:0001894 13 13 1,000 2,152E-04 9,016E-03 GO:0048871|multicellular organismal homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 2,000 2,168E-04 8,878E-03 ! protein amino acid deacetylation GO:0006476 14 14 1,000 2,509E-04 0,01005115 ! macromolecular complex disassembly GO:0032984 15 14 1,000 2,509E-04 9,837E-03 ! base-excision repair GO:0006284 14 14 1,000 2,509E-04 9,632E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 2,653E-04 9,979E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 2,892E-04 0,01065934 ! inner ear morphogenesis GO:0042472 16 16 1,000 3,302E-04 0,01193166 ! positive regulation of mitosis GO:0045840 16 16 1,000 3,302E-04 0,01170221 GO:0051785|positive regulation of nuclear division, ! cell fate specification GO:0001708 16 16 1,000 3,302E-04 0,01148141 ! positive regulation of catabolic process GO:0009896 16 16 1,000 3,302E-04 0,01126879 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 3,302E-04 0,0110639 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cellular localization GO:0060341 86 85 2,000 3,695E-04 0,01215955 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 3,738E-04 0,0120874 ! meiosis I GO:0007127 18 18 1,000 4,202E-04 0,01335092 ! negative regulation of DNA binding GO:0043392 19 18 1,000 4,202E-04 0,01312463 ! DNA replication GO:0006260 91 91 2,000 4,518E-04 0,01387658 ! metanephros development GO:0001656 19 19 1,000 4,691E-04 0,01417402 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 4,691E-04 0,0139454 ! pattern specification process GO:0007389 96 94 2,000 4,97E-04 0,01453894 ! negative regulation of binding GO:0051100 21 20 1,000 5,208E-04 0,01499613 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 5,75E-04 0,01630386 ! ear morphogenesis GO:0042471 21 21 1,000 5,75E-04 0,01605683 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 5,75E-04 0,01581718 ! anti-apoptosis GO:0006916 100 99 2,000 5,787E-04 0,01568399 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 5,96E-04 0,01591901 ! sister chromatid segregation GO:0000819 22 22 1,000 6,319E-04 0,01663709 ! embryonic skeletal system development GO:0048706 22 22 1,000 6,319E-04 0,01640277 ! maintenance of protein location in cell GO:0032507 23 22 1,000 6,319E-04 0,01617495 ! spindle organization GO:0007051 22 22 1,000 6,319E-04 0,01595337 ! cytokinesis GO:0000910 23 22 1,000 6,319E-04 0,01573779 ! epithelial cell differentiation GO:0030855 23 23 1,000 6,914E-04 0,01699032 ! viral infectious cycle GO:0019058 23 23 1,000 6,914E-04 0,01676677 ! endocrine system development GO:0035270 23 23 1,000 6,914E-04 0,01654902 ! regulation of JNK cascade GO:0046328 25 23 1,000 6,914E-04 0,01633685 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 7,535E-04 0,01757937 ! maintenance of protein location GO:0045185 25 24 1,000 7,535E-04 0,01735963 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 7,535E-04 0,01714531 ! cellular component disassembly GO:0022411 26 25 1,000 8,183E-04 0,0183911 ! maintenance of location in cell GO:0051651 27 26 1,000 8,856E-04 0,01966457 ! inner ear development GO:0048839 27 27 1,000 9,555E-04 0,02096458 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 1,028E-03 0,02229 GO:0007254|JNK cascade, ! histone modification GO:0016570 28 28 1,000 1,028E-03 0,02203082 ! positive regulation of cell cycle GO:0045787 29 29 1,000 1,103E-03 0,02336808 ! viral reproductive process GO:0022415 29 29 1,000 1,103E-03 0,02310253 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 1,103E-03 0,02284295 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 1,103E-03 0,02258914 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 1,103E-03 0,02234091 ! covalent chromatin modification GO:0016569 29 29 1,000 1,103E-03 0,02209808 ! skeletal system morphogenesis GO:0048705 31 30 1,000 1,181E-03 0,02339923 ! establishment of organelle localization GO:0051656 31 30 1,000 1,181E-03 0,0231503 ! skeletal muscle fiber development GO:0048741 31 31 1,000 1,261E-03 0,02446265 ! regulation of DNA replication GO:0006275 32 31 1,000 1,261E-03 0,02420784 ! muscle fiber development GO:0048747 32 32 1,000 1,344E-03 0,02553073 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 1,344E-03 0,02527021 ! kidney development GO:0001822 32 32 1,000 1,344E-03 0,02501495 ! maintenance of location GO:0051235 33 32 1,000 1,344E-03 0,02476481 ! regulation of cellular response to stress GO:0080135 35 33 1,000 1,429E-03 0,02607623 ! regulation of neuron differentiation GO:0045664 34 33 1,000 1,429E-03 0,02582058 ! ear development GO:0043583 34 34 1,000 1,517E-03 0,02714169 ! regulation of protein catabolic process GO:0042176 35 34 1,000 1,517E-03 0,02688071 ! viral reproduction GO:0016032 34 34 1,000 1,517E-03 0,02662471 ! regulation of mitosis GO:0007088 37 36 1,000 1,7E-03 0,02955997 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 1,7E-03 0,02928371 ! meiosis GO:0007126 37 37 1,000 1,796E-03 0,03064071 GO:0051327|M phase of meiotic cell cycle, ! chromosome segregation GO:0007059 38 38 1,000 1,893E-03 0,0320152 ! urogenital system development GO:0001655 38 38 1,000 1,893E-03 0,03172415 ! meiotic cell cycle GO:0051321 38 38 1,000 1,893E-03 0,03143835 ! activation of MAPK activity GO:0000187 39 39 1,000 1,994E-03 0,03281003 ! nucleotide-excision repair GO:0006289 40 39 1,000 1,994E-03 0,03251968 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 1,994E-03 0,03223442 ! organelle localization GO:0051640 41 40 1,000 2,097E-03 0,03360333 ! protein ubiquitination GO:0016567 43 42 1,000 2,31E-03 0,03670192 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 2,31E-03 0,03638823 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,533E-03 0,03956498 ! regulation of DNA binding GO:0051101 47 45 1,000 2,648E-03 0,04101749 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 2,648E-03 0,04067568 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,648E-03 0,04033952 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 2,648E-03 0,04000886 ! tube morphogenesis GO:0035239 47 46 1,000 2,766E-03 0,0414472 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,766E-03 0,04111295 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,766E-03 0,04078404 ! regulation of catabolic process GO:0009894 48 47 1,000 2,886E-03 0,04221766 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 3,009E-03 0,043664 ! regulation of cell cycle process GO:0010564 50 48 1,000 3,009E-03 0,04332288 ! DNA recombination GO:0006310 48 48 1,000 3,009E-03 0,04298704 ! cell cycle arrest GO:0007050 49 49 1,000 3,134E-03 0,04442846 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 3,134E-03 0,04408931 ! regulation of ligase activity GO:0051340 50 49 1,000 3,134E-03 0,0437553 ! gland development GO:0048732 51 49 1,000 3,134E-03 0,04342631 ! skeletal muscle tissue development GO:0007519 50 49 1,000 3,134E-03 0,04310224 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 1,000 3,261E-03 0,04452241 ! regulation of neurogenesis GO:0050767 51 50 1,000 3,261E-03 0,04419504 ! anatomical structure homeostasis GO:0060249 51 50 1,000 3,261E-03 0,04387245 ! cell fate commitment GO:0045165 52 52 1,000 3,523E-03 0,04705427 ! nucleosome organization GO:0034728 55 55 1,000 3,934E-03 0,05216554 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 3,934E-03 0,05179293 ! regulation of nervous system development GO:0051960 57 56 1,000 4,076E-03 0,0532786 ! regulation of binding GO:0051098 60 57 1,000 4,22E-03 0,05477406 ! regulation of cell development GO:0060284 60 59 1,000 4,516E-03 0,05819728 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,82E-03 0,06169297 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 4,82E-03 0,0612675 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 4,976E-03 0,06281523 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 4,976E-03 0,06238792 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 5,295E-03 0,06593462 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 5,458E-03 0,06750578 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 5,623E-03 0,06908427 ! striated muscle tissue development GO:0014706 69 67 1,000 5,79E-03 0,07066985 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 5,96E-03 0,07226229 ! sensory perception of sound GO:0007605 71 69 1,000 6,132E-03 0,07386138 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 6,132E-03 0,07338176 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 6,132E-03 0,07290833 ! muscle tissue development GO:0060537 72 70 1,000 6,306E-03 0,07449938 ! sensory organ development GO:0007423 72 72 1,000 6,661E-03 0,07819515 ! regulation of protein modification process GO:0031399 79 78 1,000 7,781E-03 0,09075961 ! MAPKKK cascade GO:0000165 82 81 1,000 8,371E-03 0,09702423 ! tube development GO:0035295 83 81 1,000 8,371E-03 0,09641783 ! rRNA transcription GO:0009303 5 5 0,000 8,693E-03 0,09951147 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 8,693E-03 0,0988972 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 8,693E-03 0,09829047 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 8,693E-03 0,09769114 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 8,693E-03 0,09709907 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 8,693E-03 0,09651414 ! reproductive cellular process GO:0048610 5 5 0,000 8,693E-03 0,09593621 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 8,693E-03 0,09536516 ! negative regulation of blood pressure GO:0045776 6 5 0,000 8,693E-03 0,09480087 ! prostate gland development GO:0030850 5 5 0,000 8,693E-03 0,09424321 ! metencephalon development GO:0022037 5 5 0,000 8,693E-03 0,09369208 ! water transport GO:0006833 5 5 0,000 8,693E-03 0,09314736 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 8,693E-03 0,09260894 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 8,693E-03 0,0920767 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 8,693E-03 0,09155055 ! glycerol metabolic process GO:0006071 5 5 0,000 8,693E-03 0,09103038 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 8,693E-03 0,09051608 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 8,693E-03 0,09000756 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 8,693E-03 0,08950473 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 8,693E-03 0,08900748 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 8,693E-03 0,08851573 ! filopodium assembly GO:0046847 7 5 0,000 8,693E-03 0,08802938 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 8,693E-03 0,08754834 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 8,693E-03 0,08707254 ! GTP metabolic process GO:0046039 5 5 0,000 8,693E-03 0,08660187 ! establishment of tissue polarity GO:0007164 5 5 0,000 8,693E-03 0,08613627 ! mRNA stabilization GO:0048255 5 5 0,000 8,693E-03 0,08567565 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 8,693E-03 0,08521993 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 8,693E-03 0,08476903 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 8,693E-03 0,08432288 ! social behavior GO:0035176 5 5 0,000 8,693E-03 0,0838814 ! macrophage chemotaxis GO:0048246 6 5 0,000 8,693E-03 0,08344451 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 8,693E-03 0,08301216 ! memory GO:0007613 5 5 0,000 8,693E-03 0,08258426 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 8,693E-03 0,08216075 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 8,693E-03 0,08174156 ! membrane hyperpolarization GO:0060081 5 5 0,000 8,693E-03 0,08132663 ! response to lipid GO:0033993 5 5 0,000 8,693E-03 0,08091589 ! erythrocyte maturation GO:0043249 5 5 0,000 8,693E-03 0,08050928 ! hippocampus development GO:0021766 6 5 0,000 8,693E-03 0,08010673 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 8,693E-03 0,07970819 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 8,693E-03 0,0793136 ! middle ear morphogenesis GO:0042474 5 5 0,000 8,693E-03 0,07892289 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 8,693E-03 0,07853601 ! mechanosensory behavior GO:0007638 5 5 0,000 8,693E-03 0,07815291 ! heart looping GO:0001947 5 5 0,000 8,693E-03 0,07777353 ! negative regulation of endocytosis GO:0045806 5 5 0,000 8,693E-03 0,07739781 ! response to interferon-gamma GO:0034341 5 5 0,000 8,693E-03 0,0770257 ! pseudouridine synthesis GO:0001522 5 5 0,000 8,693E-03 0,07665716 ! endocrine pancreas development GO:0031018 5 5 0,000 8,693E-03 0,07629213 ! pH reduction GO:0045851 5 5 0,000 8,693E-03 0,07593055 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 8,693E-03 0,07557239 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 8,693E-03 0,07521759 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 8,693E-03 0,0748661 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 8,693E-03 0,07451789 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 8,693E-03 0,0741729 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 8,693E-03 0,07383109 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 8,693E-03 0,07349241 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 8,693E-03 0,07315683 ! adrenal gland development GO:0030325 5 5 0,000 8,693E-03 0,0728243 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 8,693E-03 0,07249478 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 8,693E-03 0,07216823 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 8,693E-03 0,0718446 ! astrocyte differentiation GO:0048708 5 5 0,000 8,693E-03 0,07152387 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 8,693E-03 0,07120598 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 8,693E-03 0,07089091 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 8,693E-03 0,07057862 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 8,693E-03 0,07026906 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 8,693E-03 0,06996221 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 8,693E-03 0,06965803 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 8,693E-03 0,06935648 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 8,693E-03 0,06905753 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 8,693E-03 0,06876114 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 8,693E-03 0,06846729 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 8,693E-03 0,06817594 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 8,693E-03 0,06788706 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 8,693E-03 0,06760062 ! response to ATP GO:0033198 5 5 0,000 8,693E-03 0,06731658 ! regulation of type I interferon production GO:0032479 5 5 0,000 8,693E-03 0,06703492 ! regulation of appetite GO:0032098 5 5 0,000 8,693E-03 0,06675561 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 8,693E-03 0,06647862 ! paraxial mesoderm development GO:0048339 5 5 0,000 8,693E-03 0,06620391 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 8,693E-03 0,06593147 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 8,693E-03 0,06566126 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 8,693E-03 0,06539325 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,693E-03 0,06512742 ! receptor clustering GO:0043113 5 5 0,000 8,693E-03 0,06486375 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 8,693E-03 0,0646022 ! fear response GO:0042596 5 5 0,000 8,693E-03 0,06434276 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 8,693E-03 0,06408539 ! lens development in camera-type eye GO:0002088 5 5 0,000 8,693E-03 0,06383007 ! retinol metabolic process GO:0042572 5 5 0,000 8,693E-03 0,06357677 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 8,693E-03 0,06332548 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 8,693E-03 0,06307617 ! positive regulation of exocytosis GO:0045921 6 5 0,000 8,693E-03 0,06282881 ! parturition GO:0007567 5 5 0,000 8,693E-03 0,06258338 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,693E-03 0,06233987 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 8,693E-03 0,06209824 ! Schwann cell differentiation GO:0014037 5 5 0,000 8,693E-03 0,06185848 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 8,693E-03 0,06162056 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 8,693E-03 0,06138447 ! protein heterooligomerization GO:0051291 5 5 0,000 8,693E-03 0,06115018 ! regulation of gliogenesis GO:0014013 5 5 0,000 8,693E-03 0,06091767 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 8,693E-03 0,06068692 ! response to UV-B GO:0010224 5 5 0,000 8,693E-03 0,06045791 ! oligodendrocyte development GO:0014003 5 5 0,000 8,693E-03 0,06023063 ! hyaluronan metabolic process GO:0030212 5 5 0,000 8,693E-03 0,06000504 ! activated T cell proliferation GO:0050798 5 5 0,000 8,693E-03 0,05978114 ! interaction with symbiont GO:0051702 5 5 0,000 8,693E-03 0,05955891 ! cellular extravasation GO:0045123 5 5 0,000 8,693E-03 0,05933832 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 8,693E-03 0,05911936 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 8,693E-03 0,05890201 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 8,693E-03 0,05868625 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 8,693E-03 0,05847207 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 8,693E-03 0,05825944 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 8,693E-03 0,05804836 ! response to amine stimulus GO:0014075 5 5 0,000 8,693E-03 0,0578388 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 8,693E-03 0,05763074 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 8,693E-03 0,05742418 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 8,693E-03 0,05721909 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 8,693E-03 0,05701547 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 8,693E-03 0,05681329 ! neuron recognition GO:0008038 5 5 0,000 8,693E-03 0,05661253 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 8,693E-03 0,05641319 ! decidualization GO:0046697 5 5 0,000 8,693E-03 0,05621525 ! hair follicle maturation GO:0048820 5 5 0,000 8,693E-03 0,05601869 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 8,693E-03 0,05582351 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 8,693E-03 0,05562968 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 8,693E-03 0,05543718 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 8,693E-03 0,05524602 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 8,693E-03 0,05505617 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 8,693E-03 0,05486762 ! postreplication repair GO:0006301 5 5 0,000 8,693E-03 0,05468036 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 8,693E-03 0,05449438 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 8,693E-03 0,05430965 ! histone methylation GO:0016571 5 5 0,000 8,693E-03 0,05412617 ! DNA methylation GO:0006306 5 5 0,000 8,693E-03 0,05394393 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,693E-03 0,05376291 ! T cell lineage commitment GO:0002360 5 5 0,000 8,693E-03 0,0535831 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 8,693E-03 0,05340449 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 8,693E-03 0,05322706 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 8,693E-03 0,05305082 ! intracellular cholesterol transport GO:0032367 5 5 0,000 8,693E-03 0,05287573 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 8,693E-03 0,0527018 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 8,693E-03 0,052529 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 8,693E-03 0,05235734 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 8,693E-03 0,0521868 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 8,693E-03 0,05201736 ! sterol catabolic process GO:0016127 5 5 0,000 8,693E-03 0,05184902 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 8,693E-03 0,05168176 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 8,693E-03 0,05151558 ! detection of biotic stimulus GO:0009595 5 5 0,000 8,693E-03 0,05135047 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 8,693E-03 0,05118641 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 8,693E-03 0,0510234 ! zymogen activation GO:0031638 5 5 0,000 8,693E-03 0,05086142 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 8,693E-03 0,05070046 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 8,693E-03 0,05054053 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 8,693E-03 0,05038159 ! peptidyl-lysine modification GO:0018205 5 5 0,000 8,693E-03 0,05022366 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 8,693E-03 0,05006671 ! peptidyl-histidine modification GO:0018202 5 5 0,000 8,693E-03 0,04991074 ! nucleosome positioning GO:0016584 5 5 0,000 8,693E-03 0,04975573 ! regulation of isotype switching GO:0045191 5 5 0,000 8,693E-03 0,04960169 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 8,693E-03 0,0494486 ! negative regulation of neurological system process GO:0031645 5 5 0,000 8,693E-03 0,04929645 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 8,693E-03 0,04914523 ! glutathione biosynthetic process GO:0006750 5 5 0,000 8,693E-03 0,04899494 ! NADPH regeneration GO:0006740 5 5 0,000 8,693E-03 0,04884557 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 8,693E-03 0,0486971 ! positive regulation of epidermis development GO:0045684 5 5 0,000 8,693E-03 0,04854953 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 8,693E-03 0,04840286 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 8,693E-03 0,04825707 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 8,693E-03 0,04811215 ! sarcomere organization GO:0045214 5 5 0,000 8,693E-03 0,0479681 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 8,693E-03 0,04782491 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 8,693E-03 0,04768258 ! negative regulation of glucose transport GO:0010829 5 5 0,000 8,693E-03 0,04754109 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 8,693E-03 0,04740043 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 8,693E-03 0,04726061 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 8,693E-03 0,04712161 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 8,693E-03 0,04698342 ! spleen development GO:0048536 5 5 0,000 8,693E-03 0,04684604 ! male genitalia development GO:0030539 5 5 0,000 8,693E-03 0,04670946 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 8,693E-03 0,04657368 ! quaternary ammonium group transport GO:0015697 5 5 0,000 8,693E-03 0,04643869 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 8,693E-03 0,04630447 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 8,693E-03 0,04617103 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 8,693E-03 0,04603835 ! removal of superoxide radicals GO:0019430 6 5 0,000 8,693E-03 0,04590644 ! myeloid cell homeostasis GO:0002262 5 5 0,000 8,693E-03 0,04577528 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 8,693E-03 0,04564486 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 8,693E-03 0,04551519 ! ATP catabolic process GO:0006200 5 5 0,000 8,693E-03 0,04538625 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,693E-03 0,04525804 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 8,693E-03 0,04513055 ! blastocyst formation GO:0001825 5 5 0,000 8,693E-03 0,04500378 ! regulation of fibrinolysis GO:0051917 5 5 0,000 8,693E-03 0,04487772 ! embryonic gut development GO:0048566 5 5 0,000 8,693E-03 0,04475236 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 8,693E-03 0,04462771 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 8,693E-03 0,04450374 ! activation of innate immune response GO:0002218 5 5 0,000 8,693E-03 0,04438046 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 8,693E-03 0,04425786 ! catecholamine transport GO:0051937 5 5 0,000 8,693E-03 0,04413594 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 8,693E-03 0,04401469 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 8,693E-03 0,0438941 ! muscle adaptation GO:0043500 5 5 0,000 8,693E-03 0,04377417 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 8,693E-03 0,04365489 ! embryonic heart tube development GO:0035050 5 5 0,000 8,693E-03 0,04353627 ! cardiac cell differentiation GO:0035051 6 5 0,000 8,693E-03 0,04341828 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 8,693E-03 0,04330094 ! defense response to fungus GO:0050832 5 5 0,000 8,693E-03 0,04318422 ! prepulse inhibition GO:0060134 5 5 0,000 8,693E-03 0,04306814 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 8,693E-03 0,04295267 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 8,693E-03 0,04283782 ! response to nicotine GO:0035094 5 5 0,000 8,693E-03 0,04272359 ! establishment of cell polarity GO:0030010 5 5 0,000 8,693E-03 0,04260996 ! mitochondrion localization GO:0051646 5 5 0,000 8,693E-03 0,04249694 ! nucleus localization GO:0051647 5 5 0,000 8,693E-03 0,04238451 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 8,693E-03 0,04227268 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 9,397E-03 0,04557565 ! positive regulation of transferase activity GO:0051347 91 88 1,000 9,823E-03 0,04751544 GO:0033674|positive regulation of kinase activity, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01042336 0,05028862 ! axon extension GO:0048675 7 6 0,000 0,01042336 0,05015732 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01042336 0,0500267 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01042336 0,04989677 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01042336 0,0497675 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01042336 0,0496389 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01042336 0,04951097 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01042336 0,04938369 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01042336 0,04925706 ! virus-host interaction GO:0019048 6 6 0,000 0,01042336 0,04913109 ! regulation of S phase GO:0033261 6 6 0,000 0,01042336 0,04900575 ! myotube differentiation GO:0014902 6 6 0,000 0,01042336 0,04888106 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01042336 0,04875699 ! bone remodeling GO:0046849 6 6 0,000 0,01042336 0,04863356 ! N-glycan processing GO:0006491 6 6 0,000 0,01042336 0,04851074 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01042336 0,04838855 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01042336 0,04826697 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01042336 0,048146 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01042336 0,04802564 ! RNA methylation GO:0001510 6 6 0,000 0,01042336 0,04790587 ! cartilage condensation GO:0001502 7 6 0,000 0,01042336 0,0477867 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01042336 0,04766813 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01042336 0,04755014 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01042336 0,04743273 ! artery development GO:0060840 6 6 0,000 0,01042336 0,0473159 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01042336 0,04719964 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01042336 0,04708396 ! androgen metabolic process GO:0008209 6 6 0,000 0,01042336 0,04696884 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01042336 0,04685428 ! limbic system development GO:0021761 7 6 0,000 0,01042336 0,04674028 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,01042336 0,04662683 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01042336 0,04651393 ! pathogenesis GO:0009405 6 6 0,000 0,01042336 0,04640158 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01042336 0,04628977 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01042336 0,0461785 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01042336 0,04606776 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01042336 0,04595755 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01042336 0,04584786 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01042336 0,0457387 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01042336 0,04563006 ! arginine metabolic process GO:0006525 6 6 0,000 0,01042336 0,04552193 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01042336 0,04541431 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01042336 0,0453072 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01042336 0,0452006 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01042336 0,04509449 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01042336 0,04498889 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01042336 0,04488377 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01042336 0,04477915 ! ER overload response GO:0006983 6 6 0,000 0,01042336 0,04467501 ! V(D)J recombination GO:0033151 6 6 0,000 0,01042336 0,04457136 ! focal adhesion formation GO:0048041 7 6 0,000 0,01042336 0,04446818 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01042336 0,04436548 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01042336 0,04426326 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01042336 0,0441615 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01042336 0,04406022 ! regulation of heart rate GO:0002027 6 6 0,000 0,01042336 0,04395939 ! lipid digestion GO:0044241 6 6 0,000 0,01042336 0,04385903 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01042336 0,04375912 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01042336 0,04365967 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01042336 0,04356067 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01042336 0,04346211 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01042336 0,04336401 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01042336 0,04326634 ! ruffle organization GO:0031529 6 6 0,000 0,01042336 0,04316911 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01042336 0,04307232 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01042336 0,04297596 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01042336 0,04288003 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01042336 0,04278453 ! L-amino acid transport GO:0015807 6 6 0,000 0,01042336 0,04268945 ! bone mineralization GO:0030282 6 6 0,000 0,01042336 0,0425948 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01042336 0,04250056 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01042336 0,04240674 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01042336 0,04231334 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01042336 0,04222034 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01042336 0,04212775 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01042336 0,04203557 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,01042336 0,04194379 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01042336 0,04185241 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01042336 0,04176142 ! regulation of organ growth GO:0046620 6 6 0,000 0,01042336 0,04167083 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01042336 0,04158064 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01042336 0,04149083 ! response to dsRNA GO:0043331 6 6 0,000 0,01042336 0,04140141 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01042336 0,04131238 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01042336 0,04122372 ! genitalia development GO:0048806 6 6 0,000 0,01042336 0,04113545 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01042336 0,04104755 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01042336 0,04096003 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01042336 0,04087288 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01042336 0,0407861 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01042336 0,04069969 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01042336 0,04061365 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01042336 0,04052796 ! erythrocyte development GO:0048821 6 6 0,000 0,01042336 0,04044264 ! renal water homeostasis GO:0003091 6 6 0,000 0,01042336 0,04035768 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01042336 0,04027307 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01042336 0,04018882 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01042336 0,04010492 ! ribosome assembly GO:0042255 6 6 0,000 0,01042336 0,04002136 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01042336 0,03993816 ! diencephalon development GO:0021536 6 6 0,000 0,01042336 0,0398553 ! fucose catabolic process GO:0019317 6 6 0,000 0,01042336 0,03977278 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01042336 0,03969061 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,01042336 0,03960877 ! regulation of cell division GO:0051302 6 6 0,000 0,01042336 0,03952727 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01042336 0,03944611 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01042336 0,03936528 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01042336 0,03928477 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01042336 0,0392046 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01042336 0,03912475 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01042336 0,03904523 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01042336 0,03896603 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01042336 0,03888716 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01042336 0,0388086 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01042336 0,03873035 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01042336 0,03865242 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01042336 0,03857481 ! lymph node development GO:0048535 6 6 0,000 0,01042336 0,0384975 ! organic cation transport GO:0015695 6 6 0,000 0,01042336 0,03842051 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01042336 0,03834382 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01042336 0,03826744 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,01042336 0,03819136 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01042336 0,03811558 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01042336 0,03804011 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01042336 0,03796493 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01042336 0,03789005 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01042336 0,03781546 ! alditol metabolic process GO:0019400 6 6 0,000 0,01042336 0,03774117 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01042336 0,03766717 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01042336 0,03759345 ! maternal placenta development GO:0001893 6 6 0,000 0,01042336 0,03752003 ! regulation of embryonic development GO:0045995 6 6 0,000 0,01042336 0,03744689 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01042336 0,03737404 ! localization within membrane GO:0051668 6 6 0,000 0,01042336 0,03730147 ! tissue morphogenesis GO:0048729 94 93 1,000 0,01092447 0,03901898 ! regulation of response to stress GO:0080134 97 94 1,000 0,01115115 0,03975159 ! respiratory burst GO:0045730 7 7 0,000 0,01215087 0,04323178 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01215087 0,04314848 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01215087 0,0430655 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01215087 0,04298284 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01215087 0,0429005 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01215087 0,04281847 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01215087 0,04273676 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01215087 0,04265535 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01215087 0,04257426 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,01215087 0,04249347 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01215087 0,04241299 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01215087 0,04233282 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01215087 0,04225294 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01215087 0,04217337 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01215087 0,0420941 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01215087 0,04201512 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01215087 0,04193644 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,01215087 0,04185806 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01215087 0,04177996 ! visual behavior GO:0007632 7 7 0,000 0,01215087 0,04170216 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01215087 0,04162465 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01215087 0,04154742 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01215087 0,04147048 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01215087 0,04139383 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01215087 0,04131745 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01215087 0,04124136 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01215087 0,04116555 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01215087 0,04109002 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01215087 0,04101476 ! digestive system development GO:0055123 7 7 0,000 0,01215087 0,04093978 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01215087 0,04086507 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01215087 0,04079064 ! protein targeting to ER GO:0045047 8 7 0,000 0,01215087 0,04071647 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01215087 0,04064258 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01215087 0,04056895 ! endoderm development GO:0007492 7 7 0,000 0,01215087 0,04049559 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01215087 0,04042249 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01215087 0,04034966 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,01215087 0,04027709 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01215087 0,04020478 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01215087 0,04013272 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01215087 0,04006093 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01215087 0,03998939 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01215087 0,03991811 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01215087 0,03984708 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01215087 0,03977631 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01215087 0,03970578 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01215087 0,0396355 ! response to X-ray GO:0010165 7 7 0,000 0,01215087 0,03956548 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01215087 0,0394957 ! UV protection GO:0009650 7 7 0,000 0,01215087 0,03942616 ! myofibril assembly GO:0030239 7 7 0,000 0,01215087 0,03935687 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01215087 0,03928782 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01215087 0,03921902 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01215087 0,03915045 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01215087 0,03908213 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01215087 0,03901404 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01215087 0,03894619 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01215087 0,03887858 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01215087 0,0388112 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01215087 0,03874405 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01215087 0,03867713 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01215087 0,03861045 ! axon cargo transport GO:0008088 7 7 0,000 0,01215087 0,03854399 ! eating behavior GO:0042755 7 7 0,000 0,01215087 0,03847777 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01215087 0,03841177 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01215087 0,03834599 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01215087 0,03828044 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01215087 0,03821512 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01215087 0,03815002 ! cranial nerve development GO:0021545 7 7 0,000 0,01215087 0,03808514 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01215087 0,03802048 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01215087 0,03795603 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01215087 0,03789181 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01215087 0,0378278 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01215087 0,03776401 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01215087 0,03770044 ! platelet activation GO:0030168 8 7 0,000 0,01215087 0,03763708 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01215087 0,03757393 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01215087 0,03751099 ! natural killer cell activation GO:0030101 7 7 0,000 0,01215087 0,03744826 ! response to gamma radiation GO:0010332 8 7 0,000 0,01215087 0,03738574 ! NADP metabolic process GO:0006739 7 7 0,000 0,01215087 0,03732343 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01215087 0,03726133 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01215087 0,03719943 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01215087 0,03713774 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01215087 0,03707626 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01215087 0,03701497 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01215087 0,03695389 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01215087 0,03689301 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01215087 0,03683234 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01215087 0,03677186 ! cell-cell recognition GO:0009988 8 7 0,000 0,01215087 0,03671157 ! hormone catabolic process GO:0042447 7 7 0,000 0,01215087 0,03665149 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01215087 0,0365916 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01215087 0,03653191 ! oxygen transport GO:0015671 7 7 0,000 0,01215087 0,03647241 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01215087 0,03641311 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01215087 0,03635399 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01215087 0,03629507 ! regulation of axon extension GO:0030516 7 7 0,000 0,01215087 0,03623634 ! cell killing GO:0001906 7 7 0,000 0,01215087 0,0361778 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01215087 0,03611945 ! adult feeding behavior GO:0008343 7 7 0,000 0,01215087 0,03606129 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01215087 0,03600331 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01215087 0,03594552 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01215087 0,03588792 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01215087 0,0358305 ! response to cold GO:0009409 7 7 0,000 0,01215087 0,03577326 ! muscle organ development GO:0007517 102 100 1,000 0,01255512 0,03690444 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01387562 0,04072097 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01387562 0,04065623 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01387562 0,0405917 ! positive regulation of translation GO:0045727 8 8 0,000 0,01387562 0,04052737 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01387562 0,04046324 ! superoxide anion generation GO:0042554 8 8 0,000 0,01387562 0,04039932 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01387562 0,0403356 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01387562 0,04027208 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01387562 0,04020876 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01387562 0,04014563 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01387562 0,04008271 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01387562 0,04001998 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01387562 0,03995745 ! zinc ion transport GO:0006829 8 8 0,000 0,01387562 0,03989512 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01387562 0,03983297 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01387562 0,03977103 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01387562 0,03970927 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01387562 0,0396477 ! lipid localization GO:0010876 8 8 0,000 0,01387562 0,03958633 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01387562 0,03952515 ! response to cAMP GO:0051591 8 8 0,000 0,01387562 0,03946415 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01387562 0,03940334 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01387562 0,03934272 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01387562 0,03928229 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01387562 0,03922204 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01387562 0,03916197 ! sensory perception of taste GO:0050909 8 8 0,000 0,01387562 0,03910209 ! organelle fusion GO:0048284 8 8 0,000 0,01387562 0,0390424 ! pancreas development GO:0031016 8 8 0,000 0,01387562 0,03898288 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01387562 0,03892355 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01387562 0,03886439 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01387562 0,03880542 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01387562 0,03874662 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01387562 0,038688 ! sperm motility GO:0030317 8 8 0,000 0,01387562 0,03862956 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01387562 0,0385713 ! glycine metabolic process GO:0006544 8 8 0,000 0,01387562 0,03851321 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01387562 0,03845529 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01387562 0,03839755 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01387562 0,03833998 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01387562 0,03828259 ! Golgi organization GO:0007030 8 8 0,000 0,01387562 0,03822537 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01387562 0,03816831 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,01387562 0,03811143 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01387562 0,03805472 ! fructose metabolic process GO:0006000 8 8 0,000 0,01387562 0,03799817 ! mannose metabolic process GO:0006013 9 8 0,000 0,01387562 0,03794179 ! NAD metabolic process GO:0019674 8 8 0,000 0,01387562 0,03788558 ! sex determination GO:0007530 8 8 0,000 0,01387562 0,03782954 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01387562 0,03777366 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01387562 0,03771795 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01387562 0,0376624 ! response to fungus GO:0009620 8 8 0,000 0,01387562 0,03760701 ! stem cell differentiation GO:0048863 8 8 0,000 0,01387562 0,03755179 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01387562 0,03749673 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01387562 0,03744183 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01387562 0,03738709 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01387562 0,03733251 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01387562 0,03727809 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01387562 0,03722383 ! vasoconstriction GO:0042310 8 8 0,000 0,01387562 0,03716972 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01387562 0,03711578 ! muscle cell development GO:0055001 8 8 0,000 0,01387562 0,03706198 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01387562 0,03700835 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01387562 0,03695487 ! sensory perception of pain GO:0019233 8 8 0,000 0,01387562 0,03690154 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01387562 0,03684837 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01387562 0,03679535 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01387562 0,03674248 ! chromatin silencing GO:0006342 8 8 0,000 0,01387562 0,03668977 ! tissue regeneration GO:0042246 8 8 0,000 0,01387562 0,03663721 ! salivary gland development GO:0007431 8 8 0,000 0,01387562 0,03658479 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01387562 0,03653253 ! T cell homeostasis GO:0043029 8 8 0,000 0,01387562 0,03648041 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01387562 0,03642845 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01387562 0,03637663 ! water homeostasis GO:0030104 8 8 0,000 0,01387562 0,03632496 ! cofactor transport GO:0051181 8 8 0,000 0,01387562 0,03627343 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01387562 0,03622205 ! acid secretion GO:0046717 8 8 0,000 0,01387562 0,03617082 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01387562 0,03611973 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01387562 0,03606879 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01387562 0,03601799 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01387562 0,03596733 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01387562 0,03591681 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01387562 0,03586644 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01387562 0,0358162 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01387562 0,03576611 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01387562 0,03571616 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01387562 0,03566635 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,01387562 0,03561667 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01387562 0,03556713 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01387562 0,03551774 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01387562 0,03546847 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01387562 0,03541935 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01387562 0,03537036 ! peptide hormone secretion GO:0030072 8 8 0,000 0,01387562 0,0353215 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01387562 0,03527279 ! actin filament polymerization GO:0030041 9 8 0,000 0,01387562 0,0352242 ! peptide hormone processing GO:0016486 8 8 0,000 0,01387562 0,03517575 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01387562 0,03512743 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01387562 0,03507924 ! lactation GO:0007595 10 9 0,000 0,01559761 0,03937862 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01559761 0,03932475 ! positive regulation of cell size GO:0045793 9 9 0,000 0,01559761 0,03927103 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01559761 0,03921745 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01559761 0,03916402 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01559761 0,03911074 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01559761 0,0390576 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01559761 0,0390046 ! viral genome replication GO:0019079 9 9 0,000 0,01559761 0,03895175 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01559761 0,03889904 ! copper ion transport GO:0006825 9 9 0,000 0,01559761 0,03884647 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01559761 0,03879405 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01559761 0,03874177 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01559761 0,03868962 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01559761 0,03863762 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01559761 0,03858576 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01559761 0,03853404 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01559761 0,03848245 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01559761 0,038431 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01559761 0,03837969 ! phospholipid efflux GO:0033700 9 9 0,000 0,01559761 0,03832852 ! response to alkaloid GO:0043279 10 9 0,000 0,01559761 0,03827748 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01559761 0,03822658 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01559761 0,03817582 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01559761 0,03812519 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01559761 0,03807469 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01559761 0,03802433 ! response to ethanol GO:0045471 9 9 0,000 0,01559761 0,0379741 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01559761 0,037924 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01559761 0,03787403 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01559761 0,0378242 ! methionine metabolic process GO:0006555 9 9 0,000 0,01559761 0,0377745 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01559761 0,03772492 ! cerebral cortex development GO:0021987 9 9 0,000 0,01559761 0,03767548 ! response to osmotic stress GO:0006970 9 9 0,000 0,01559761 0,03762617 ! pigmentation during development GO:0048066 9 9 0,000 0,01559761 0,03757698 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01559761 0,03752793 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01559761 0,037479 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01559761 0,0374302 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01559761 0,03738152 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01559761 0,03733298 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01559761 0,03728455 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,01559761 0,03723626 ! L-glutamate transport GO:0015813 9 9 0,000 0,01559761 0,03718809 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01559761 0,03714004 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,01559761 0,03709212 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01559761 0,03704432 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01559761 0,03699664 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01559761 0,03694909 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01559761 0,03690166 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01559761 0,03685435 ! DNA replication initiation GO:0006270 9 9 0,000 0,01559761 0,03680716 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01559761 0,03676009 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01559761 0,03671314 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01559761 0,03666631 ! histone acetylation GO:0016573 9 9 0,000 0,01559761 0,03661961 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01559761 0,03657302 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01559761 0,03652655 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01559761 0,03648019 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01559761 0,03643396 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01559761 0,03638784 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01559761 0,03634183 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01559761 0,03629595 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01559761 0,03625018 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01559761 0,03620452 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01559761 0,03615898 ! collagen catabolic process GO:0030574 9 9 0,000 0,01559761 0,03611356 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01559761 0,03606824 ! purine base metabolic process GO:0006144 9 9 0,000 0,01559761 0,03602305 ! gas transport GO:0015669 9 9 0,000 0,01559761 0,03597796 ! cholesterol efflux GO:0033344 9 9 0,000 0,01559761 0,03593299 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01559761 0,03588813 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01559761 0,03584338 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01559761 0,03579874 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,01559761 0,03575422 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01559761 0,0357098 ! defense response to virus GO:0051607 9 9 0,000 0,01559761 0,0356655 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01559761 0,0356213 ! actin filament-based movement GO:0030048 9 9 0,000 0,01559761 0,03557722 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01559761 0,03553324 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01731684 0,03940115 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01731684 0,03935257 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01731684 0,0393041 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01731684 0,03925576 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01731684 0,03920753 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01731684 0,03915943 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01731684 0,03911144 ! neuron maturation GO:0042551 10 10 0,000 0,01731684 0,03906356 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01731684 0,03901581 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01731684 0,03896817 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01731684 0,03892065 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01731684 0,03887324 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01731684 0,03882595 ! hormone secretion GO:0046879 10 10 0,000 0,01731684 0,03877877 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01731684 0,03873171 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01731684 0,03868477 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,01731684 0,03863793 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01731684 0,03859121 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01731684 0,0385446 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01731684 0,03849811 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01731684 0,03845172 ! glial cell development GO:0021782 10 10 0,000 0,01731684 0,03840545 ! phototransduction GO:0007602 11 10 0,000 0,01731684 0,03835929 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01731684 0,03831324 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01731684 0,0382673 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,01731684 0,03822148 ! fat cell differentiation GO:0045444 10 10 0,000 0,01731684 0,03817576 ! myoblast differentiation GO:0045445 10 10 0,000 0,01731684 0,03813015 ! centrosome cycle GO:0007098 10 10 0,000 0,01731684 0,03808464 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01731684 0,03803925 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01731684 0,03799397 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01731684 0,03794879 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01731684 0,03790372 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01731684 0,03785876 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01731684 0,0378139 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01731684 0,03776915 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01731684 0,03772451 ! plasma membrane organization GO:0007009 10 10 0,000 0,01731684 0,03767997 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01731684 0,03763553 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01731684 0,0375912 ! lysosomal transport GO:0007041 10 10 0,000 0,01731684 0,03754698 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01731684 0,03750286 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01731684 0,03745884 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01731684 0,03741493 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01731684 0,03737111 ! exocrine system development GO:0035272 10 10 0,000 0,01731684 0,03732741 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01731684 0,0372838 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01731684 0,03724029 ! embryo implantation GO:0007566 11 10 0,000 0,01731684 0,03719689 ! regulation of protein binding GO:0043393 11 10 0,000 0,01731684 0,03715359 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01731684 0,03711039 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01731684 0,03706728 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01731684 0,03702428 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01731684 0,03698138 ! protein export from nucleus GO:0006611 10 10 0,000 0,01731684 0,03693858 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01731684 0,03689587 ! cytolysis GO:0019835 10 10 0,000 0,01731684 0,03685327 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01731684 0,03681076 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01731684 0,03676835 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01731684 0,03672604 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01731684 0,03668383 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01731684 0,03664171 ! gland morphogenesis GO:0022612 10 10 0,000 0,01731684 0,03659969 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01731684 0,03655777 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01731684 0,03651594 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01731684 0,03647421 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01731684 0,03643257 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01731684 0,03639103 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01731684 0,03634958 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01731684 0,03630823 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01731684 0,03626697 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01731684 0,0362258 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01731684 0,03618473 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01731684 0,03614375 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01731684 0,03610286 ! nerve development GO:0021675 10 10 0,000 0,01731684 0,03606207 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01731684 0,03602137 ! gut development GO:0048565 10 10 0,000 0,01731684 0,03598076 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01731684 0,03594024 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01731684 0,03589981 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01731684 0,03585947 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01731684 0,03581923 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01731684 0,03577907 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01731684 0,03573901 ! protein stabilization GO:0050821 10 10 0,000 0,01731684 0,03569903 ! protein secretion GO:0009306 11 11 0,000 0,01903331 0,03919374 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01903331 0,03915 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01903331 0,03910635 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01903331 0,03906281 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01903331 0,03901935 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01903331 0,038976 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01903331 0,03893274 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01903331 0,03888958 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01903331 0,03884651 ! skin development GO:0043588 11 11 0,000 0,01903331 0,03880354 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01903331 0,03876066 ! signal complex assembly GO:0007172 11 11 0,000 0,01903331 0,03871788 ! microtubule-based transport GO:0010970 11 11 0,000 0,01903331 0,03867519 ! endothelial cell migration GO:0043542 11 11 0,000 0,01903331 0,0386326 ! peroxisomal transport GO:0043574 11 11 0,000 0,01903331 0,0385901 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01903331 0,03854769 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01903331 0,03850538 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01903331 0,03846316 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01903331 0,03842103 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01903331 0,03837899 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01903331 0,03833705 ! T cell proliferation GO:0042098 11 11 0,000 0,01903331 0,0382952 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01903331 0,03825343 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01903331 0,03821176 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01903331 0,03817018 ! spinal cord development GO:0021510 11 11 0,000 0,01903331 0,03812869 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01903331 0,0380873 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01903331 0,03804599 ! cellular response to starvation GO:0009267 11 11 0,000 0,01903331 0,03800477 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01903331 0,03796364 ! digestive system process GO:0022600 11 11 0,000 0,01903331 0,03792259 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01903331 0,03788164 ! fucose metabolic process GO:0006004 11 11 0,000 0,01903331 0,03784078 ! membrane budding GO:0006900 11 11 0,000 0,01903331 0,0378 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01903331 0,03775931 ! monoamine transport GO:0015844 11 11 0,000 0,01903331 0,03771871 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01903331 0,03767819 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01903331 0,03763777 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01903331 0,03759743 ! body fluid secretion GO:0007589 11 11 0,000 0,01903331 0,03755717 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01903331 0,037517 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01903331 0,03747692 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01903331 0,03743693 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01903331 0,03739701 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01903331 0,03735719 ! membrane depolarization GO:0051899 11 11 0,000 0,01903331 0,03731745 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01903331 0,03727779 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01903331 0,03723822 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01903331 0,03719873 ! oogenesis GO:0048477 11 11 0,000 0,01903331 0,03715932 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01903331 0,03712 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01903331 0,03708076 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01903331 0,0370416 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01903331 0,03700253 ! muscle maintenance GO:0046716 12 11 0,000 0,01903331 0,03696354 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01903331 0,03692463 ! hindbrain development GO:0030902 11 11 0,000 0,01903331 0,0368858 ! steroid catabolic process GO:0006706 11 11 0,000 0,01903331 0,03684706 ! endocrine process GO:0050886 11 11 0,000 0,01903331 0,03680839 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01903331 0,03676981 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01903331 0,03673131 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01903331 0,03669289 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01903331 0,03665454 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01903331 0,03661628 ! translational initiation GO:0006413 12 12 0,000 0,02074704 0,03987153 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,02074704 0,03983 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,02074704 0,03978855 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,02074704 0,03974719 ! iron ion transport GO:0006826 13 12 0,000 0,02074704 0,03970592 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,02074704 0,03966473 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,02074704 0,03962363 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,02074704 0,03958261 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,02074704 0,03954168 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,02074704 0,03950083 ! collagen metabolic process GO:0032963 12 12 0,000 0,02074704 0,03946006 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,02074704 0,03941938 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,02074704 0,03937879 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,02074704 0,03933827 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,02074704 0,03929784 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,02074704 0,0392575 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,02074704 0,03921723 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,02074704 0,03917705 ! actomyosin structure organization GO:0031032 12 12 0,000 0,02074704 0,03913695 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,02074704 0,03909693 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,02074704 0,039057 ! retinoid metabolic process GO:0001523 12 12 0,000 0,02074704 0,03901714 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,02074704 0,03897737 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,02074704 0,03893768 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,02074704 0,03889807 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,02074704 0,03885854 ! acute-phase response GO:0006953 12 12 0,000 0,02074704 0,03881909 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,02074704 0,03877972 ! vacuolar transport GO:0007034 12 12 0,000 0,02074704 0,03874043 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,02074704 0,03870122 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,02074704 0,03866208 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,02074704 0,03862303 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,02074704 0,03858406 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,02074704 0,03854516 ! male gonad development GO:0008584 12 12 0,000 0,02074704 0,03850634 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,02074704 0,03846761 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,02074704 0,03842895 ! renal system process GO:0003014 12 12 0,000 0,02074704 0,03839036 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,02074704 0,03835186 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,02074704 0,03831343 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,02074704 0,03827508 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,02074704 0,0382368 ! pallium development GO:0021543 13 12 0,000 0,02074704 0,0381986 ! cell fate determination GO:0001709 12 12 0,000 0,02074704 0,03816048 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,02074704 0,03812243 ! somitogenesis GO:0001756 13 12 0,000 0,02074704 0,03808446 ! G1 phase GO:0051318 13 12 0,000 0,02074704 0,03804657 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,02074704 0,03800875 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,02074704 0,037971 ! detection of light stimulus GO:0009583 13 12 0,000 0,02074704 0,03793333 ! synaptogenesis GO:0007416 12 12 0,000 0,02074704 0,03789574 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,02074704 0,03785822 ! hormone transport GO:0009914 12 12 0,000 0,02074704 0,03782077 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,02074704 0,0377834 ! heme biosynthetic process GO:0006783 12 12 0,000 0,02074704 0,0377461 ! spermatid differentiation GO:0048515 13 12 0,000 0,02074704 0,03770888 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,02074704 0,03767172 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,02074704 0,03763465 ! neural tube closure GO:0001843 13 12 0,000 0,02074704 0,03759764 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,02074704 0,03756071 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,02074704 0,03752385 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,02074704 0,03748706 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,02245803 0,04053883 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,02245803 0,04049916 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,02245803 0,04045957 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,02245803 0,04042006 ! phenol metabolic process GO:0018958 13 13 0,000 0,02245803 0,04038063 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,02245803 0,04034127 ! gluconeogenesis GO:0006094 13 13 0,000 0,02245803 0,04030199 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,02245803 0,04026279 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,02245803 0,04022366 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,02245803 0,04018461 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,02245803 0,04014563 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,02245803 0,04010673 ! regeneration GO:0031099 13 13 0,000 0,02245803 0,0400679 ! keratinization GO:0031424 13 13 0,000 0,02245803 0,04002915 ! post-embryonic development GO:0009791 14 13 0,000 0,02245803 0,03999048 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,02245803 0,03995188 ! patterning of blood vessels GO:0001569 13 13 0,000 0,02245803 0,03991335 ! vasculogenesis GO:0001570 13 13 0,000 0,02245803 0,0398749 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,02245803 0,03983652 ! regulation of innate immune response GO:0045088 13 13 0,000 0,02245803 0,03979821 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,02245803 0,03975998 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,02245803 0,03972183 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,02245803 0,03968374 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,02245803 0,03964573 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,02245803 0,03960779 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,02245803 0,03956993 ! autophagy GO:0006914 13 13 0,000 0,02245803 0,03953213 ! receptor metabolic process GO:0043112 14 13 0,000 0,02245803 0,03949441 ! actin filament bundle formation GO:0051017 13 13 0,000 0,02245803 0,03945676 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,02245803 0,03941918 ! cell aging GO:0007569 13 13 0,000 0,02245803 0,03938168 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,02245803 0,03934424 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,02245803 0,03930688 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,02245803 0,03926959 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,02245803 0,03923236 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,02245803 0,03919521 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,02245803 0,03915813 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,02245803 0,03912112 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,02245803 0,03908418 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,02245803 0,0390473 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,02245803 0,0390105 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,02245803 0,03897377 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,02245803 0,03893711 ! vasodilation GO:0042311 14 13 0,000 0,02245803 0,03890051 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,02245803 0,03886398 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,02245803 0,03882753 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,02245803 0,03879114 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,02245803 0,03875482 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,02245803 0,03871856 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,02245803 0,03868238 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,02245803 0,03864626 ! immunoglobulin production GO:0002377 13 13 0,000 0,02245803 0,03861021 GO:0002440|production of molecular mediator of immune response, ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,02245803 0,03857422 ! cell-cell junction organization GO:0045216 13 13 0,000 0,02245803 0,03853831 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,02245803 0,03850246 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,02245803 0,03846668 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,02245803 0,03843096 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,02245803 0,03839531 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,02245803 0,03835972 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,02245803 0,03832421 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,02245803 0,03828875 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,02245803 0,03825337 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,02245803 0,03821805 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,02245803 0,03818279 ! blastocyst development GO:0001824 13 13 0,000 0,02245803 0,0381476 ! telomere organization GO:0032200 13 13 0,000 0,02245803 0,03811247 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,02245803 0,03807741 ! regulation of amine transport GO:0051952 13 13 0,000 0,02245803 0,03804241 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,02245803 0,03800748 ! protein tetramerization GO:0051262 13 13 0,000 0,02245803 0,03797261 ! neuron fate commitment GO:0048663 14 14 0,000 0,02416627 0,0408235 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02416627 0,04078611 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02416627 0,0407488 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02416627 0,04071155 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02416627 0,04067437 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02416627 0,04063726 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02416627 0,04060021 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02416627 0,04056324 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02416627 0,04052633 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02416627 0,04048949 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02416627 0,04045271 ! vesicle docking GO:0048278 14 14 0,000 0,02416627 0,040416 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02416627 0,04037936 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02416627 0,04034279 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02416627 0,04030628 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02416627 0,04026983 ! hair cycle GO:0042633 14 14 0,000 0,02416627 0,04023346 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02416627 0,04019714 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02416627 0,0401609 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02416627 0,04012472 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02416627 0,0400886 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02416627 0,04005255 ! lysosome organization GO:0007040 14 14 0,000 0,02416627 0,04001656 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02416627 0,03998064 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02416627 0,03994478 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02416627 0,03990899 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02416627 0,03987326 ! primary neural tube formation GO:0014020 15 14 0,000 0,02416627 0,0398376 ! peptide cross-linking GO:0018149 14 14 0,000 0,02416627 0,039802 ! regulation of behavior GO:0050795 14 14 0,000 0,02416627 0,03976646 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02416627 0,03973099 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02416627 0,03969557 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02416627 0,03966023 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02416627 0,03962494 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02416627 0,03958972 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02416627 0,03955456 ! collagen fibril organization GO:0030199 14 14 0,000 0,02416627 0,03951946 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02416627 0,03948443 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02416627 0,03944946 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02416627 0,03941454 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02416627 0,03937969 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02416627 0,03934491 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02416627 0,03931018 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02416627 0,03927552 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02416627 0,03924091 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,02416627 0,03920637 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02587178 0,0419364 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02587178 0,04189955 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,02587178 0,04186276 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02587178 0,04182604 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,02587178 0,04178938 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02587178 0,04175279 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02587178 0,04171626 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02587178 0,04167979 ! response to vitamin GO:0033273 15 15 0,000 0,02587178 0,04164339 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,02587178 0,04160705 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02587178 0,04157078 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02587178 0,04153457 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,02587178 0,04149842 ! ovarian follicle development GO:0001541 15 15 0,000 0,02587178 0,04146233 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02587178 0,04142631 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02587178 0,04139035 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02587178 0,04135445 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02587178 0,04131862 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02587178 0,04128284 ! heme metabolic process GO:0042168 15 15 0,000 0,02587178 0,04124713 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02587178 0,04121148 ! chromosome condensation GO:0030261 15 15 0,000 0,02587178 0,04117589 ! response to starvation GO:0042594 15 15 0,000 0,02587178 0,04114036 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02587178 0,0411049 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02587178 0,04106949 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02587178 0,04103415 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02587178 0,04099887 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02587178 0,04096364 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02587178 0,04092848 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02587178 0,04089338 ! phospholipid transport GO:0015914 15 15 0,000 0,02587178 0,04085834 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02587178 0,04082336 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02587178 0,04078844 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02587178 0,04075357 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02587178 0,04071877 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02587178 0,04068403 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02587178 0,04064935 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02587178 0,04061472 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02587178 0,04058016 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02587178 0,04054565 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02587178 0,0405112 ! protein homooligomerization GO:0051260 15 15 0,000 0,02587178 0,04047681 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02587178 0,04044248 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02757455 0,04306771 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02757455 0,04303124 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02757455 0,04299483 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02757455 0,04295849 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02757455 0,04292221 ! learning GO:0007612 16 16 0,000 0,02757455 0,04288599 ! circadian rhythm GO:0007623 16 16 0,000 0,02757455 0,04284983 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02757455 0,04281373 ! vacuole organization GO:0007033 16 16 0,000 0,02757455 0,04277769 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02757455 0,04274171 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02757455 0,04270579 ! vesicle targeting GO:0006903 17 16 0,000 0,02757455 0,04266994 ! segmentation GO:0035282 17 16 0,000 0,02757455 0,04263414 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02757455 0,0425984 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02757455 0,04256273 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02757455 0,04252711 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02757455 0,04249155 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02757455 0,04245605 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02757455 0,04242061 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02757455 0,04238523 ! pentose metabolic process GO:0019321 16 16 0,000 0,02757455 0,04234991 ! fatty acid transport GO:0015908 16 16 0,000 0,02757455 0,04231465 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02757455 0,04227945 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02757455 0,0422443 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02757455 0,04220921 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02757455 0,04217419 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02757455 0,04213922 ! polyol metabolic process GO:0019751 16 16 0,000 0,02757455 0,0421043 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02757455 0,04206945 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02757455 0,04203465 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02757455 0,04199991 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02757455 0,04196523 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02757455 0,04193061 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02757455 0,04189604 ! regulation of coagulation GO:0050818 17 16 0,000 0,02757455 0,04186153 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,02927459 0,04440582 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,02927459 0,04436931 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,02927459 0,04433285 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,02927459 0,04429645 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,02927459 0,04426011 ! myelination GO:0042552 17 17 0,000 0,02927459 0,04422383 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,02927459 0,04418761 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,02927459 0,04415145 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,02927459 0,04411535 ! leukocyte adhesion GO:0007159 17 17 0,000 0,02927459 0,04407931 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,02927459 0,04404333 ! sensory perception of smell GO:0007608 17 17 0,000 0,02927459 0,0440074 ! glucose transport GO:0015758 17 17 0,000 0,02927459 0,04397154 ! cell junction assembly GO:0034329 18 17 0,000 0,02927459 0,04393573 ! tissue remodeling GO:0048771 17 17 0,000 0,02927459 0,04389998 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,02927459 0,04386429 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,02927459 0,04382866 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,02927459 0,04379308 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,02927459 0,04375756 ! neural crest cell development GO:0014032 19 17 0,000 0,02927459 0,0437221 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,02927459 0,0436867 ! negative regulation of cell development GO:0010721 18 17 0,000 0,02927459 0,04365136 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,02927459 0,04361607 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,02927459 0,04358084 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,02927459 0,04354566 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,02927459 0,04351054 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,02927459 0,04347548 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,02927459 0,04344048 ! pigmentation GO:0043473 17 17 0,000 0,02927459 0,04340553 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,02927459 0,04337064 ! adult locomotory behavior GO:0008344 17 17 0,000 0,02927459 0,0433358 ! embryonic organ development GO:0048568 17 17 0,000 0,02927459 0,04330102 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,02927459 0,0432663 ! liver development GO:0001889 17 17 0,000 0,02927459 0,04323163 ! gene silencing GO:0016458 17 17 0,000 0,02927459 0,04319702 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,03097191 0,04566499 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,03097191 0,04562849 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,03097191 0,04559204 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,03097191 0,04555566 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,03097191 0,04551933 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,03097191 0,04548306 ! membrane docking GO:0022406 18 18 0,000 0,03097191 0,04544684 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,03097191 0,04541069 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,03097191 0,04537459 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,03097191 0,04533855 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,03097191 0,04530257 ! hexose transport GO:0008645 18 18 0,000 0,03097191 0,04526664 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,03097191 0,04523077 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,03097191 0,04519496 ! striated muscle contraction GO:0006941 18 18 0,000 0,03097191 0,04515921 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,03097191 0,04512351 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,03097191 0,04508786 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,03097191 0,04505228 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,03097191 0,04501675 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,03097191 0,04498127 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,03097191 0,04494586 ! B cell differentiation GO:0030183 18 18 0,000 0,03097191 0,04491049 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,03097191 0,04487519 ! ensheathment of neurons GO:0007272 18 18 0,000 0,03097191 0,04483993 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,03097191 0,04480474 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,03097191 0,0447696 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,03097191 0,04473451 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,03097191 0,04469948 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,03097191 0,0446645 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,03266651 0,04707145 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,03266651 0,04703467 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,03266651 0,04699796 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,03266651 0,0469613 ! glial cell differentiation GO:0010001 19 19 0,000 0,03266651 0,04692469 ! regulation of pH GO:0006885 19 19 0,000 0,03266651 0,04688815 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,03266651 0,04685166 ! feeding behavior GO:0007631 19 19 0,000 0,03266651 0,04681523 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,03266651 0,04677885 ! peroxisome organization GO:0007031 19 19 0,000 0,03266651 0,04674253 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,03266651 0,04670627 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,03266651 0,04667006 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,03266651 0,04663391 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,03266651 0,04659782 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,03266651 0,04656178 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,03266651 0,0465258 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,03266651 0,04648987 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,03266651 0,046454 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,03266651 0,04641818 ! peripheral nervous system development GO:0007422 19 19 0,000 0,03266651 0,04638242 ! regulation of protein stability GO:0031647 19 19 0,000 0,03266651 0,04634671 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,03266651 0,04631106 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,03266651 0,04627547 ! eye morphogenesis GO:0048592 19 19 0,000 0,03266651 0,04623992 ! regulation of cell shape GO:0008360 21 19 0,000 0,03266651 0,04620444 ! placenta development GO:0001890 19 19 0,000 0,03266651 0,046169 ! response to heat GO:0009408 19 19 0,000 0,03266651 0,04613363 ! vesicle localization GO:0051648 20 19 0,000 0,03266651 0,0460983 ! regulation of muscle development GO:0048634 21 20 0,000 0,03435839 0,04844875 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,03435839 0,04841171 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,03435839 0,04837473 ! organic ether metabolic process GO:0018904 20 20 0,000 0,03435839 0,0483378 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,03435839 0,04830093 ! neural tube development GO:0021915 21 20 0,000 0,03435839 0,04826412 ! nucleus organization GO:0006997 20 20 0,000 0,03435839 0,04822736 ! phagocytosis GO:0006909 21 20 0,000 0,03435839 0,04819065 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,03435839 0,04815401 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,03435839 0,04811742 ! protein targeting to membrane GO:0006612 22 20 0,000 0,03435839 0,04808088 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,03435839 0,0480444 ! chromatin remodeling GO:0006338 20 20 0,000 0,03435839 0,04800798 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,03435839 0,04797161 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,03435839 0,04793529 ! lipid oxidation GO:0034440 20 20 0,000 0,03435839 0,04789903 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,03435839 0,04786283 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,03435839 0,04782668 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,03435839 0,04779058 ! RNA modification GO:0009451 20 20 0,000 0,03435839 0,04775454 ! single fertilization GO:0007338 21 20 0,000 0,03435839 0,04771855 ! regulation of B cell activation GO:0050864 20 20 0,000 0,03435839 0,04768262 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03604756 0,04998921 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03604756 0,04995162 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03604756 0,04991409 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03604756 0,04987662 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03604756 0,0498392 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03604756 0,04980184 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03604756 0,04976454 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03604756 0,04972729 ! organic anion transport GO:0015711 21 21 0,000 0,03604756 0,0496901 ! cholesterol transport GO:0030301 21 21 0,000 0,03604756 0,04965296 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03604756 0,04961588 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03604756 0,04957885 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03604756 0,04954188 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03604756 0,04950496 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03604756 0,0494681 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03604756 0,04943129 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03604756 0,04939454 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03604756 0,04935784 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,03604756 0,0493212 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03604756 0,04928461 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,03604756 0,04924808 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03773402 0,05151393 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,03773402 0,0514758 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03773402 0,05143772 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03773402 0,05139971 ! regulation of ion transport GO:0043269 22 22 0,000 0,03773402 0,05136175 ! odontogenesis GO:0042476 22 22 0,000 0,03773402 0,05132384 ! cell junction organization GO:0034330 23 22 0,000 0,03773402 0,05128599 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03773402 0,0512482 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03773402 0,05121046 ! ovulation cycle process GO:0022602 22 22 0,000 0,03773402 0,05117278 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03773402 0,05113515 ! cell chemotaxis GO:0060326 23 22 0,000 0,03773402 0,05109758 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03773402 0,05106006 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03773402 0,0510226 ! male sex differentiation GO:0046661 22 22 0,000 0,03773402 0,05098519 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03773402 0,05094784 ! biopolymer methylation GO:0043414 22 22 0,000 0,03773402 0,05091054 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03773402 0,0508733 ! detection of external stimulus GO:0009581 23 22 0,000 0,03773402 0,05083611 ! neuron migration GO:0001764 22 22 0,000 0,03773402 0,05079898 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03773402 0,0507619 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03773402 0,05072488 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03773402 0,0506879 ! aerobic respiration GO:0009060 22 22 0,000 0,03773402 0,05065099 ! cytokine production GO:0001816 22 22 0,000 0,03773402 0,05061412 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03773402 0,05057731 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03941778 0,05279576 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03941778 0,05275742 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03941778 0,05271913 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,03941778 0,0526809 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03941778 0,05264273 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03941778 0,05260461 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03941778 0,05256654 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03941778 0,05252854 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03941778 0,05249058 ! positive regulation of growth GO:0045927 23 23 0,000 0,03941778 0,05245268 ! female gonad development GO:0008585 23 23 0,000 0,03941778 0,05241484 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03941778 0,05237705 ! lipid homeostasis GO:0055088 23 23 0,000 0,03941778 0,05233931 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03941778 0,05230163 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03941778 0,052264 ! cell projection assembly GO:0030031 25 23 0,000 0,03941778 0,05222643 ! mitochondrial transport GO:0006839 24 24 0,000 0,04109883 0,05441462 ! regulation of action potential GO:0001508 24 24 0,000 0,04109883 0,05437555 ! gliogenesis GO:0042063 24 24 0,000 0,04109883 0,05433655 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,04109883 0,0542976 ! glucose homeostasis GO:0042593 24 24 0,000 0,04109883 0,0542587 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,04109883 0,05421986 ! T cell differentiation GO:0030217 24 24 0,000 0,04109883 0,05418108 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,04109883 0,05414235 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,04109883 0,05410368 ! ovulation cycle GO:0042698 24 24 0,000 0,04109883 0,05406506 ! fertilization GO:0009566 25 24 0,000 0,04109883 0,0540265 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,04109883 0,05398799 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,04109883 0,05394953 ! glucan metabolic process GO:0044042 25 24 0,000 0,04109883 0,05391114 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,04277719 0,0560728 ! negative regulation of secretion GO:0051048 26 25 0,000 0,04277719 0,05603295 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,04277719 0,05599315 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,04277719 0,05595341 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,04277719 0,05591373 ! endosome transport GO:0016197 25 25 0,000 0,04277719 0,0558741 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,04277719 0,05583453 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,04277719 0,05579502 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,04277719 0,05575556 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,04277719 0,05571615 ! excretion GO:0007588 25 25 0,000 0,04277719 0,05567681 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,04277719 0,05563751 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,04277719 0,05559828 ! gastrulation GO:0007369 25 25 0,000 0,04277719 0,0555591 ! heart morphogenesis GO:0003007 25 25 0,000 0,04277719 0,05551997 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,04277719 0,0554809 ! regulation of endocytosis GO:0030100 25 25 0,000 0,04277719 0,05544188 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,04277719 0,05540292 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,04277719 0,05536402 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,04277719 0,05532516 ! positive regulation of binding GO:0051099 27 26 0,000 0,04445285 0,05745204 ! positive regulation of defense response GO:0031349 26 26 0,000 0,04445285 0,05741178 ! glycolysis GO:0006096 26 26 0,000 0,04445285 0,05737157 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,04445285 0,05733143 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,04445285 0,05729133 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,04445285 0,0572513 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,04445285 0,05721132 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,04445285 0,05717139 ! cellular defense response GO:0006968 26 26 0,000 0,04445285 0,05713152 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,04445285 0,05709171 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,04445285 0,05705195 ! double-strand break repair GO:0006302 27 26 0,000 0,04445285 0,05701225 ! regulation of protein secretion GO:0050708 26 26 0,000 0,04445285 0,05697261 ! germ cell development GO:0007281 27 26 0,000 0,04445285 0,05693301 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,04445285 0,05689348 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,04445285 0,05685399 ! response to insulin stimulus GO:0032868 28 26 0,000 0,04445285 0,05681457 ! synapse organization GO:0050808 26 26 0,000 0,04445285 0,0567752 ! chloride transport GO:0006821 27 27 0,000 0,04612583 0,05887112 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,04612583 0,05883038 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,04612583 0,05878969 ! learning or memory GO:0007611 28 27 0,000 0,04612583 0,05874907 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,04612583 0,05870849 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,04612583 0,05866798 ! peptide metabolic process GO:0006518 29 27 0,000 0,04612583 0,05862752 ! activation of caspase activity GO:0006919 27 27 0,000 0,04612583 0,05858711 ! mesenchymal cell development GO:0014031 29 27 0,000 0,04612583 0,05854676 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 0,000 0,04612583 0,05850647 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,04612583 0,05846623 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,04612583 0,05842605 ! cell growth GO:0016049 27 27 0,000 0,04612583 0,05838592 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,04779612 0,06045864 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,04779612 0,06041717 ! carbohydrate transport GO:0008643 28 28 0,000 0,04779612 0,06037576 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,04779612 0,06033441 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,04779612 0,06029311 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,04779612 0,06025187 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,04779612 0,06021069 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,04779612 0,06016956 ! developmental growth GO:0048589 28 28 0,000 0,04779612 0,06012849 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,04779612 0,06008748 ! cartilage development GO:0051216 29 28 0,000 0,04779612 0,06004652 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04946372 0,06209921 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04946372 0,06205694 ! leukocyte migration GO:0050900 30 29 0,000 0,04946372 0,06201472 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04946372 0,06197256 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04946372 0,06193046 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04946372 0,06188842 ! tRNA processing GO:0008033 29 29 0,000 0,04946372 0,06184643 ! adult behavior GO:0030534 30 29 0,000 0,04946372 0,0618045 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,04946372 0,06176263 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04946372 0,06172081 ! response to UV GO:0009411 29 29 0,000 0,04946372 0,06167905 ! transition metal ion transport GO:0000041 31 30 0,000 0,05112865 0,06371204 ! RNA catabolic process GO:0006401 30 30 0,000 0,05112865 0,06366899 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,05112865 0,063626 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,05112865 0,06358307 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,05112865 0,06354019 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,05112865 0,06349738 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,05112865 0,06345462 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,05112865 0,06341192 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,05112865 0,06336927 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,05112865 0,06332668 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,05112865 0,06328416 ! response to temperature stimulus GO:0009266 30 30 0,000 0,05112865 0,06324168 ! regulation of ossification GO:0030278 30 30 0,000 0,05112865 0,06319927 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,05112865 0,06315691 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,05112865 0,06311461 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,05112865 0,06307236 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,05112865 0,06303017 ! vesicle organization GO:0016050 30 30 0,000 0,05112865 0,06298804 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,05112865 0,06294596 ! regulation of translational initiation GO:0006446 31 31 0,000 0,05279091 0,06494903 ! membrane fusion GO:0006944 31 31 0,000 0,05279091 0,0649057 ! B cell activation GO:0042113 31 31 0,000 0,05279091 0,06486243 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,05279091 0,06481922 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,05279091 0,06477606 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,05279091 0,06473296 ! ion transmembrane transport GO:0034220 31 31 0,000 0,05279091 0,06468992 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,05279091 0,06464694 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,05279091 0,06460401 ! digestion GO:0007586 31 31 0,000 0,05279091 0,06456115 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,05279091 0,06451833 ! regulation of heart contraction GO:0008016 31 31 0,000 0,05279091 0,06447558 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,05279091 0,06443288 ! camera-type eye development GO:0043010 31 31 0,000 0,05279091 0,06439024 ! extracellular matrix organization GO:0030198 31 31 0,000 0,05279091 0,06434765 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,05279091 0,06430512 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,05279091 0,06426265 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,05279091 0,06422023 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,05279091 0,06417787 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,0544505 0,06615179 ! cell redox homeostasis GO:0045454 32 32 0,000 0,0544505 0,06610821 ! glucose catabolic process GO:0006007 32 32 0,000 0,0544505 0,06606469 ! lipid modification GO:0030258 32 32 0,000 0,0544505 0,06602123 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,0544505 0,06597782 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,0544505 0,06593447 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,0544505 0,06589118 ! cell maturation GO:0048469 32 32 0,000 0,0544505 0,06584794 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,0544505 0,06580476 ! nuclear export GO:0051168 32 32 0,000 0,0544505 0,06576164 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,0544505 0,06571857 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,0544505 0,06567557 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,0544505 0,06563261 ! negative regulation of cell size GO:0045792 33 33 0,000 0,05610742 0,0675856 ! amino acid transport GO:0006865 33 33 0,000 0,05610742 0,06754146 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,05610742 0,06749737 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,05610742 0,06745334 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,05610742 0,06740937 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,05610742 0,06736545 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,05610742 0,06732159 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,05610742 0,06727779 ! regulation of actin filament length GO:0030832 34 34 0,000 0,05776168 0,06921636 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,05776168 0,06917139 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,05776168 0,06912647 ! response to metal ion GO:0010038 34 34 0,000 0,05776168 0,06908161 ! muscle cell differentiation GO:0042692 35 34 0,000 0,05776168 0,06903681 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,05776168 0,06899207 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,05776168 0,06894739 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,05776168 0,06890276 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,05776168 0,06885819 ! secondary metabolic process GO:0019748 34 34 0,000 0,05776168 0,06881368 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,05776168 0,06876923 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,05776168 0,06872483 ! detection of stimulus GO:0051606 36 34 0,000 0,05776168 0,0686805 ! acute inflammatory response GO:0002526 35 35 0,000 0,05941328 0,07059875 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,05941328 0,07055327 ! regulation of cellular component size GO:0032535 35 35 0,000 0,05941328 0,07050784 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,05941328 0,07046246 ! mesoderm development GO:0007498 35 35 0,000 0,05941328 0,07041715 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,05941328 0,0703719 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,05941328 0,0703267 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,05941328 0,07028156 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,05941328 0,07023648 ! inorganic anion transport GO:0015698 35 35 0,000 0,05941328 0,07019145 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,05941328 0,07014649 ! regulation of immune effector process GO:0002697 35 35 0,000 0,05941328 0,07010158 ! hydrogen transport GO:0006818 36 36 0,000 0,06106222 0,07200107 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,06106222 0,07195504 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,06106222 0,07190906 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,06106222 0,07186314 ! positive regulation of cell migration GO:0030335 36 36 0,000 0,06106222 0,07181728 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,06106222 0,07177148 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,06106222 0,07172573 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,06106222 0,07168005 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,06106222 0,07163442 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,06106222 0,07158885 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,06106222 0,07154334 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,06106222 0,07149789 ! gonad development GO:0008406 36 36 0,000 0,06106222 0,07145249 ! regulation of lipase activity GO:0060191 36 36 0,000 0,06106222 0,07140716 ! activation of immune response GO:0002253 36 36 0,000 0,06106222 0,07136188 ! coagulation GO:0050817 39 36 0,000 0,06106222 0,07131665 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,06270852 0,07319303 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,06270852 0,07314671 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,06270852 0,07310044 ! response to drug GO:0042493 37 37 0,000 0,06270852 0,07305424 ! lung development GO:0030324 38 37 0,000 0,06270852 0,07300809 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,06270852 0,072962 ! eye development GO:0001654 37 37 0,000 0,06270852 0,07291596 ! negative regulation of growth GO:0045926 37 37 0,000 0,06270852 0,07286999 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,06270852 0,07282407 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,06270852 0,07277821 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,06270852 0,07273241 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,06270852 0,07268667 ! adaptive immune response GO:0002250 37 37 0,000 0,06270852 0,07264098 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,06435217 0,07449815 ! neurotransmitter transport GO:0006836 40 38 0,000 0,06435217 0,07445138 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,06435217 0,07440467 ! exocytosis GO:0006887 40 38 0,000 0,06435217 0,07435802 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,06435217 0,07431143 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,06435217 0,0742649 ! hexose catabolic process GO:0019320 38 38 0,000 0,06435217 0,07421843 ! RNA elongation GO:0006354 38 38 0,000 0,06435217 0,07417201 ! axon guidance GO:0007411 39 38 0,000 0,06435217 0,07412566 ! regulation of neurological system process GO:0031644 38 38 0,000 0,06435217 0,07407936 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,06435217 0,07403311 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,06435217 0,07398693 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,06599318 0,07582633 ! hemostasis GO:0007599 42 39 0,000 0,06599318 0,07577908 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,06599318 0,0757319 ! respiratory tube development GO:0030323 40 39 0,000 0,06599318 0,07568477 ! response to unfolded protein GO:0006986 39 39 0,000 0,06599318 0,0756377 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,06599318 0,07559069 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,06599318 0,07554374 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,06599318 0,07549685 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,06599318 0,07545002 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,06599318 0,07540324 ! respiratory system development GO:0060541 40 39 0,000 0,06599318 0,07535652 ! developmental maturation GO:0021700 39 39 0,000 0,06599318 0,07530986 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,06599318 0,07526326 ! limb development GO:0060173 39 39 0,000 0,06599318 0,07521671 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,06599318 0,07517023 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,06599318 0,0751238 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,06763155 0,07694132 ! DNA catabolic process GO:0006308 41 40 0,000 0,06763155 0,07689386 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,06763155 0,07684645 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,06763155 0,0767991 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,06763155 0,07675181 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,06926728 0,07855975 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,06926728 0,07851144 ! amine catabolic process GO:0009310 42 41 0,000 0,06926728 0,07846318 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,06926728 0,07841499 ! regulation of caspase activity GO:0043281 41 41 0,000 0,06926728 0,07836685 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,06926728 0,07831877 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,06926728 0,07827075 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,06926728 0,07822279 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,06926728 0,07817489 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,07090038 0,07996904 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,07090038 0,07992013 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,07090038 0,07987128 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,07090038 0,07982248 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,07090038 0,07977375 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,07090038 0,07972508 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,07090038 0,07967647 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,07090038 0,07962791 ! forebrain development GO:0030900 43 42 0,000 0,07090038 0,07957942 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,07090038 0,07953098 ! reproductive structure development GO:0048608 43 43 0,000 0,07253086 0,08131045 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,07253086 0,08126102 ! mitochondrion organization GO:0007005 44 43 0,000 0,07253086 0,08121165 ! alcohol catabolic process GO:0046164 43 43 0,000 0,07253086 0,08116234 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,07253086 0,08111309 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,07253086 0,0810639 ! humoral immune response GO:0006959 44 44 0,000 0,07415871 0,08283303 ! mRNA transport GO:0051028 44 44 0,000 0,07415871 0,08278286 ! protein import into nucleus GO:0006606 44 44 0,000 0,07415871 0,08273275 ! vitamin metabolic process GO:0006766 44 44 0,000 0,07415871 0,0826827 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,07415871 0,08263271 ! amine biosynthetic process GO:0009309 46 45 0,000 0,07578395 0,08439264 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,07578395 0,08434167 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,07578395 0,08429077 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,07578395 0,08423994 ! nuclear import GO:0051170 45 45 0,000 0,07578395 0,08418916 ! protein processing GO:0016485 45 45 0,000 0,07578395 0,08413844 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,07740656 0,0858882 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,07740656 0,08583652 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,07740656 0,08578491 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,07740656 0,08573335 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,07740656 0,08568186 ! regulation of membrane potential GO:0042391 46 46 0,000 0,07740656 0,08563043 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,07902657 0,08737011 ! regulation of blood pressure GO:0008217 48 47 0,000 0,07902657 0,08731773 ! sex differentiation GO:0007548 47 47 0,000 0,07902657 0,08726541 ! amine transport GO:0015837 47 47 0,000 0,07902657 0,08721315 ! rhythmic process GO:0048511 47 47 0,000 0,07902657 0,08716096 ! calcium ion transport GO:0006816 48 48 0,000 0,08064397 0,08889165 ! actin filament organization GO:0007015 50 48 0,000 0,08064397 0,08883851 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,08064397 0,08878544 ! protein localization in nucleus GO:0034504 48 48 0,000 0,08064397 0,08873244 ! leukocyte differentiation GO:0002521 50 49 0,000 0,08225876 0,09045519 ! ossification GO:0001503 50 49 0,000 0,08225876 0,09040125 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,08225876 0,09034738 ! divalent metal ion transport GO:0070838 49 49 0,000 0,08225876 0,09029357 ! response to nutrient GO:0007584 49 49 0,000 0,08225876 0,09023982 ! response to bacterium GO:0009617 50 49 0,000 0,08225876 0,09018614 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,08225876 0,09013252 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,08225876 0,09007897 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,08387096 0,09178989 ! chromatin assembly GO:0031497 50 50 0,000 0,08387096 0,09173541 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,08387096 0,091681 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,08387096 0,09162666 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,08387096 0,09157238 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,08387096 0,09151816 ! transcription initiation GO:0006352 50 50 0,000 0,08387096 0,09146401 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,08387096 0,09140992 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,08548055 0,09310914 ! positive regulation of immune response GO:0050778 51 51 0,000 0,08548055 0,09305414 ! rRNA metabolic process GO:0016072 51 51 0,000 0,08548055 0,09299921 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,08548055 0,09294434 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,08548055 0,09288954 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,08548055 0,0928348 ! protein maturation GO:0051604 51 51 0,000 0,08548055 0,09278013 ! RNA localization GO:0006403 52 52 0,000 0,08708756 0,09446873 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,08708756 0,09441316 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,08708756 0,09435765 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,08708756 0,09430221 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,08708756 0,09424684 ! response to light stimulus GO:0009416 53 52 0,000 0,08708756 0,09419153 ! sodium ion transport GO:0006814 53 53 0,000 0,08869197 0,09587056 ! tRNA metabolic process GO:0006399 53 53 0,000 0,08869197 0,09581436 ! response to hypoxia GO:0001666 53 53 0,000 0,08869197 0,09575823 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,08869197 0,09570217 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,08869197 0,09564617 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,08869197 0,09559024 ! regulation of T cell activation GO:0050863 53 53 0,000 0,08869197 0,09553437 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,0902938 0,09720297 ! response to oxygen levels GO:0070482 55 54 0,000 0,0902938 0,09714622 ! response to virus GO:0009615 54 54 0,000 0,0902938 0,09708954 ! hormone metabolic process GO:0042445 55 54 0,000 0,0902938 0,09703293 ! sulfur metabolic process GO:0006790 55 54 0,000 0,0902938 0,09697639 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,0902938 0,09691991 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,09189305 0,0985791 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,09189305 0,09852175 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,09189305 0,09846447 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,09348972 0,10011712 ! reproductive developmental process GO:0003006 56 56 0,000 0,09348972 0,10005898 ! extracellular structure organization GO:0043062 56 56 0,000 0,09348972 0,10000091 ! ATP metabolic process GO:0046034 57 57 0,000 0,09508382 0,10164703 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,09508382 0,10158811 ! innate immune response GO:0045087 58 58 0,000 0,09667535 0,10322866 ! dephosphorylation GO:0016311 60 59 0,000 0,09826431 0,10486458 ! carboxylic acid transport GO:0046942 59 59 0,000 0,09826431 0,10480389 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,09826431 0,10474328 ! sterol metabolic process GO:0016125 59 59 0,000 0,09826431 0,10468273 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,09826431 0,10462226 ! protein localization in organelle GO:0033365 59 59 0,000 0,09826431 0,10456185 ! immune effector process GO:0002252 59 59 0,000 0,09826431 0,10450151 ! potassium ion transport GO:0006813 60 60 0,000 0,09985071 0,10612737 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,09985071 0,1060662 ! protein polymerization GO:0051258 65 60 0,000 0,09985071 0,1060051 ! cellular respiration GO:0045333 62 61 0,000 0,10143455 0,10762457 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,10143455 0,10756264 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,10143455 0,10750079 ! lipid transport GO:0006869 62 62 0,000 0,10301584 0,1091139 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,10301584 0,10905123 ! axonogenesis GO:0007409 66 62 0,000 0,10301584 0,10898863 ! protein import GO:0017038 62 62 0,000 0,10301584 0,1089261 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,10301584 0,10886364 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,10301584 0,10880125 ! regulation of secretion GO:0051046 65 63 0,000 0,10459457 0,11040538 ! glucose metabolic process GO:0006006 63 63 0,000 0,10459457 0,11034218 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,10459457 0,11027906 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,10459457 0,11021601 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,10617076 0,11181297 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,10617076 0,11174912 ! angiogenesis GO:0001525 65 64 0,000 0,10617076 0,11168533 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,10617076 0,11162162 ! anion transport GO:0006820 65 65 0,000 0,1077444 0,11321148 ! regulation of hormone levels GO:0010817 66 65 0,000 0,1077444 0,11314697 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,1093155 0,11473148 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,1093155 0,11466618 ! DNA packaging GO:0006323 66 66 0,000 0,1093155 0,11460095 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,1093155 0,1145358 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,1093155 0,11447072 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,11088407 0,11604733 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,11088407 0,11598146 ! muscle contraction GO:0006936 67 67 0,000 0,11088407 0,11591568 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,11088407 0,11584997 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,11088407 0,11578433 ! response to radiation GO:0009314 70 68 0,000 0,1124501 0,11735308 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,1124501 0,11728667 ! regulation of cell size GO:0008361 68 68 0,000 0,1124501 0,11722033 ! regulation of translation GO:0006417 69 69 0,000 0,11401361 0,11878297 ! response to nutrient levels GO:0031667 69 69 0,000 0,11401361 0,11871587 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,11401361 0,11864883 ! positive regulation of transport GO:0051050 71 70 0,000 0,11557459 0,1202054 ! cell part morphogenesis GO:0032990 75 70 0,000 0,11557459 0,1201376 ! wound healing GO:0042060 74 70 0,000 0,11557459 0,12006988 ! growth GO:0040007 70 70 0,000 0,11557459 0,12000224 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,11557459 0,11993467 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,11713305 0,12148352 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,11713305 0,12141519 ! regulation of cell migration GO:0030334 71 71 0,000 0,11713305 0,12134694 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,11713305 0,12127877 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,11713305 0,12121067 ! regulation of cell activation GO:0050865 71 71 0,000 0,11713305 0,12114265 ! secretion by cell GO:0032940 75 72 0,000 0,11868899 0,12268301 ! muscle system process GO:0003012 72 72 0,000 0,11868899 0,12261424 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,11868899 0,12254555 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,11868899 0,12247694 ! regulation of cytokine production GO:0001817 72 72 0,000 0,11868899 0,1224084 ! electron transport chain GO:0022900 75 74 0,000 0,12179333 0,12553977 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,12179333 0,1254696 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,12334174 0,12699376 ! response to oxidative stress GO:0006979 76 75 0,000 0,12334174 0,12692286 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,12334174 0,12685203 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,12488765 0,1283703 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,12643106 0,1298843 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,12643106 0,12981195 ! microtubule-based movement GO:0007018 82 78 0,000 0,12797197 0,1313209 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,12797197 0,13124783 ! metal ion homeostasis GO:0055065 78 78 0,000 0,12797197 0,13117483 ! regulation of immune response GO:0050776 78 78 0,000 0,12797197 0,13110191 ! regulation of locomotion GO:0040012 79 79 0,000 0,12951039 0,13260425 ! nuclear transport GO:0051169 79 79 0,000 0,12951039 0,13253062 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,12951039 0,13245708 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,13104632 0,13395362 ! neuron projection development GO:0031175 85 80 0,000 0,13104632 0,13387937 ! lymphocyte activation GO:0046649 82 81 0,000 0,13257977 0,13537093 ! lipid catabolic process GO:0016042 82 81 0,000 0,13257977 0,13529597 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,13563923 0,1383415 ! ncRNA processing GO:0034470 83 83 0,000 0,13563923 0,13826499 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,13563923 0,13818856 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,13716524 0,13966605 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,13868879 0,14113939 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,13868879 0,1410615 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,13868879 0,1409837 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,14020987 0,14245137 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,14020987 0,14237289 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,14020987 0,14229449 ! heart development GO:0007507 90 87 0,000 0,14172849 0,14375652 ! male gamete generation GO:0048232 90 88 0,000 0,14324464 0,14521445 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,14324464 0,14513462 ! chemotaxis GO:0006935 90 89 0,000 0,14475835 0,14658771 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,14475835 0,14650721 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,1462696 0,14795547 ! brain development GO:0007420 91 90 0,000 0,1462696 0,14787431 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,1477784 0,14931776 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,1477784 0,14923594 ! visual perception GO:0007601 93 92 0,000 0,14928475 0,15067459 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,14928475 0,15059212 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,14928475 0,15050974 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,14928475 0,15042745 ! blood vessel development GO:0001568 95 94 0,000 0,15229015 0,15337199 ! epidermis development GO:0008544 94 94 0,000 0,15229015 0,15328823 ! cofactor metabolic process GO:0051186 95 94 0,000 0,15229015 0,15320456 ! regulation of cell growth GO:0001558 97 96 0,000 0,15528581 0,15613298 ! vasculature development GO:0001944 97 96 0,000 0,15528581 0,15604784 ! endocytosis GO:0006897 99 98 0,000 0,15827176 0,15896177 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,15827176 0,15887519 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,15827176 0,15878871 ! blood circulation GO:0008015 99 98 0,000 0,15827176 0,15870232 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,15827176 0,15861602 ! ectoderm development GO:0007398 99 99 0,000 0,15976111 0,16002159 ! response to hormone stimulus GO:0009725 102 100 0,000 0,16124804 0,16142321 ! response to other organism GO:0051707 101 100 0,000 0,16124804 0,16133558 ! hemopoiesis GO:0030097 104 100 0,000 0,16124804 0,16124804