pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/11143-0-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 3,57E-07 8,59E-04 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 8,454E-07 1,017E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 8,454E-07 6,78E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,458E-06 8,773E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,542E-06 7,42E-04 ! interphase GO:0051325 213 98 3,000 1,746E-06 7,003E-04 ! regulation of chromosome organization GO:0033044 42 27 2,000 1,853E-06 6,368E-04 ! negative regulation of protein transport GO:0051224 69 33 2,000 3,443E-06 1,036E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 4,498E-06 1,202E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 7,206E-06 1,734E-03 ! muscle cell migration GO:0014812 8 5 1,000 7,727E-06 1,69E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 7,727E-06 1,549E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 9,506E-06 1,759E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 9,506E-06 1,634E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,082E-05 1,735E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 1,158E-05 1,742E-03 GO:0051653|spindle localization, ! response to UV GO:0009411 104 53 2,000 1,461E-05 2,068E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,621E-05 2,167E-03 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 1,000 1,621E-05 2,053E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,82E-05 2,19E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,82E-05 2,086E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,16E-05 2,362E-03 ! nucleosome disassembly GO:0006337 14 8 1,000 2,16E-05 2,259E-03 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 2,776E-05 2,782E-03 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 1,000 2,776E-05 2,671E-03 ! induction of an organ GO:0001759 14 9 1,000 2,776E-05 2,568E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 3,097E-05 2,76E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 3,236E-05 2,781E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,468E-05 2,877E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,468E-05 2,781E-03 ! protein sumoylation GO:0016925 15 10 1,000 3,468E-05 2,691E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 3,677E-05 2,765E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 3,677E-05 2,681E-03 ! thyroid gland development GO:0030878 26 11 1,000 4,236E-05 2,997E-03 ! thymus development GO:0048538 27 11 1,000 4,236E-05 2,912E-03 ! developmental induction GO:0031128 19 11 1,000 4,236E-05 2,831E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 1,000 4,236E-05 2,754E-03 GO:0019047|provirus integration, ! positive regulation of ligase activity GO:0051351 124 77 2,000 4,497E-05 2,847E-03 ! negative regulation of organelle organization GO:0010639 161 78 2,000 4,674E-05 2,883E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 4,855E-05 2,921E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,08E-05 2,981E-03 ! negative regulation of transport GO:0051051 153 84 2,000 5,833E-05 3,341E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 5,833E-05 3,264E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 6E-05 3,281E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 6E-05 3,208E-03 ! regulation of protein transport GO:0051223 154 87 2,000 6,477E-05 3,388E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of mRNA processing GO:0050684 24 14 1,000 6,997E-05 3,582E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 6,997E-05 3,507E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 6,997E-05 3,435E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 7,901E-05 3,802E-03 GO:0010498|proteasomal protein catabolic process, ! histone deacetylation GO:0016575 20 15 1,000 8,068E-05 3,806E-03 ! regulation of protein localization GO:0032880 176 97 2,000 8,956E-05 4,144E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 9,216E-05 4,184E-03 ! cell cycle arrest GO:0007050 213 100 2,000 9,804E-05 4,368E-03 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,044E-04 4,567E-03 ! DNA integration GO:0015074 29 17 1,000 1,044E-04 4,485E-03 ! DNA unwinding during replication GO:0006268 27 17 1,000 1,044E-04 4,406E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,311E-04 5,439E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! protein amino acid deacetylation GO:0006476 29 20 1,000 1,456E-04 5,937E-03 ! DNA duplex unwinding GO:0032508 31 20 1,000 1,456E-04 5,838E-03 GO:0032392|DNA geometric change, ! axis specification GO:0009798 38 21 1,000 1,608E-04 6,344E-03 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 1,608E-04 6,241E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 1,768E-04 6,753E-03 ! ureteric bud development GO:0001657 43 22 1,000 1,768E-04 6,647E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,768E-04 6,545E-03 ! activation of JUN kinase activity GO:0007257 42 22 1,000 1,768E-04 6,446E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,768E-04 6,35E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,11E-04 7,467E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,11E-04 7,359E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,293E-04 7,88E-03 ! initiation of viral infection GO:0019059 57 26 1,000 2,482E-04 8,412E-03 ! macromolecular complex disassembly GO:0032984 53 26 1,000 2,482E-04 8,295E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,482E-04 8,181E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,482E-04 8,071E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 2,482E-04 7,963E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 2,482E-04 7,858E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,679E-04 8,372E-03 ! fat cell differentiation GO:0045444 50 27 1,000 2,679E-04 8,265E-03 ! base-excision repair GO:0006284 41 27 1,000 2,679E-04 8,16E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,884E-04 8,673E-03 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 2,884E-04 8,566E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,096E-04 9,083E-03 ! tissue homeostasis GO:0001894 48 29 1,000 3,096E-04 8,974E-03 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 50 30 1,000 3,315E-04 9,495E-03 ! inner ear morphogenesis GO:0042472 47 31 1,000 3,542E-04 0,01002513 ! spindle organization GO:0007051 46 32 1,000 3,776E-04 0,01056329 ! metanephros development GO:0001656 74 32 1,000 3,776E-04 0,01044187 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,776E-04 0,01032321 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,776E-04 0,01020722 ! cell fate specification GO:0001708 52 33 1,000 4,017E-04 0,01073908 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 4,522E-04 0,01195559 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 4,785E-04 0,01251435 ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,785E-04 0,01237978 ! meiosis I GO:0007127 65 37 1,000 5,056E-04 0,01294082 ! sister chromatid segregation GO:0000819 58 37 1,000 5,056E-04 0,0128046 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,056E-04 0,01267122 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,334E-04 0,01322997 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 5,619E-04 0,01379518 ! negative regulation of binding GO:0051100 72 40 1,000 5,911E-04 0,01436662 ! maintenance of protein location GO:0045185 91 40 1,000 5,911E-04 0,01422296 ! cytokinesis GO:0000910 72 40 1,000 5,911E-04 0,01408214 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 6,211E-04 0,01465106 ! epithelial cell differentiation GO:0030855 79 43 1,000 6,832E-04 0,01595974 ! maintenance of location in cell GO:0051651 97 44 1,000 7,154E-04 0,01654981 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 7,482E-04 0,01714515 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 7,482E-04 0,0169834 ! response to calcium ion GO:0051592 81 47 1,000 8,161E-04 0,0183509 ! JNK cascade GO:0007254 91 47 1,000 8,161E-04 0,01818098 ! regulation of JNK cascade GO:0046328 94 47 1,000 8,161E-04 0,01801419 ! cellular component disassembly GO:0022411 86 48 1,000 8,511E-04 0,01861624 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 8,511E-04 0,01844852 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 8,511E-04 0,01828381 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 8,868E-04 0,01888272 ! endocrine system development GO:0035270 104 49 1,000 8,868E-04 0,01871708 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 8,868E-04 0,01855432 ! inner ear development GO:0048839 79 50 1,000 9,233E-04 0,01915022 ! histone modification GO:0016570 91 50 1,000 9,233E-04 0,01898654 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 9,233E-04 0,01882564 ! viral infectious cycle GO:0019058 99 51 1,000 9,604E-04 0,01941865 ! embryonic skeletal system development GO:0048706 85 51 1,000 9,604E-04 0,01925683 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 9,604E-04 0,01909768 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 9,604E-04 0,01894114 ! covalent chromatin modification GO:0016569 101 52 1,000 9,983E-04 0,01952784 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 9,983E-04 0,01937036 ! regulation of protein catabolic process GO:0042176 116 55 1,000 1,116E-03 0,02148388 ! skeletal muscle fiber development GO:0048741 111 56 1,000 1,157E-03 0,02209055 ! nucleotide-excision repair GO:0006289 83 56 1,000 1,157E-03 0,02191661 ! regulation of DNA replication GO:0006275 101 56 1,000 1,157E-03 0,02174539 ! positive regulation of organelle organization GO:0010638 100 56 1,000 1,157E-03 0,02157682 ! muscle fiber development GO:0048747 112 57 1,000 1,198E-03 0,02217717 ! maintenance of location GO:0051235 118 57 1,000 1,198E-03 0,02200788 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,283E-03 0,02338907 ! establishment of organelle localization GO:0051656 109 59 1,000 1,283E-03 0,02321321 ! kidney development GO:0001822 122 60 1,000 1,327E-03 0,02382131 ! ear development GO:0043583 103 62 1,000 1,416E-03 0,02523337 ! viral reproductive process GO:0022415 126 62 1,000 1,416E-03 0,02504783 ! regulation of mitosis GO:0007088 105 63 1,000 1,461E-03 0,02566607 GO:0051783|regulation of nuclear division, ! regulation of cellular response to stress GO:0080135 128 67 1,000 1,651E-03 0,02878249 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 1,651E-03 0,02857543 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,651E-03 0,02837132 ! activation of MAPK activity GO:0000187 115 67 1,000 1,651E-03 0,0281701 ! chromosome segregation GO:0007059 113 67 1,000 1,651E-03 0,02797172 ! negative regulation of kinase activity GO:0033673 131 68 1,000 1,7E-03 0,02860202 ! viral reproduction GO:0016032 134 68 1,000 1,7E-03 0,0284034 ! negative regulation of cell size GO:0045792 134 69 1,000 1,75E-03 0,0290335 ! urogenital system development GO:0001655 137 69 1,000 1,75E-03 0,02883464 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 1,851E-03 0,03030184 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,903E-03 0,03093994 ! negative regulation of transferase activity GO:0051348 140 72 1,000 1,903E-03 0,03073229 ! meiosis GO:0007126 121 74 1,000 2,009E-03 0,03222362 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 1,000 2,009E-03 0,03201022 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 2,063E-03 0,03265282 ! meiotic cell cycle GO:0051321 122 75 1,000 2,063E-03 0,0324394 ! regulation of catabolic process GO:0009894 161 76 1,000 2,117E-03 0,03308155 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,173E-03 0,03372599 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,285E-03 0,03524601 ! response to metal ion GO:0010038 140 80 1,000 2,343E-03 0,03589969 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,401E-03 0,03655541 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 1,000 2,401E-03 0,0363255 ! negative regulation of growth GO:0045926 155 84 1,000 2,579E-03 0,03877505 ! response to unfolded protein GO:0006986 131 85 1,000 2,639E-03 0,03944099 ! positive regulation of cell activation GO:0050867 145 85 1,000 2,639E-03 0,03919753 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 2,701E-03 0,03986261 ! tube morphogenesis GO:0035239 176 86 1,000 2,701E-03 0,03961955 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,825E-03 0,04119789 ! regulation of DNA binding GO:0051101 155 88 1,000 2,825E-03 0,04094971 ! gland development GO:0048732 206 88 1,000 2,825E-03 0,0407045 ! regulation of cell cycle process GO:0010564 149 90 1,000 2,953E-03 0,04228645 ! response to protein stimulus GO:0051789 149 91 1,000 3,017E-03 0,04295717 ! nucleosome organization GO:0034728 138 92 1,000 3,083E-03 0,04362941 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 3,149E-03 0,04430312 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 3,419E-03 0,04783177 ! protein ubiquitination GO:0016567 217 97 1,000 3,419E-03 0,04755529 ! skeletal muscle tissue development GO:0007519 186 99 1,000 3,559E-03 0,04920794 GO:0060538|skeletal muscle organ development, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 4,475E-03 0,0615219 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,475E-03 0,06117234 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,475E-03 0,06082674 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,475E-03 0,06048501 ! neuron fate determination GO:0048664 7 5 0,000 4,475E-03 0,06014711 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,475E-03 0,05981296 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,475E-03 0,0594825 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,475E-03 0,05915567 ! polyol transport GO:0015791 12 5 0,000 4,475E-03 0,05883242 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,475E-03 0,05851268 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,475E-03 0,05819639 ! response to superoxide GO:0000303 10 5 0,000 4,475E-03 0,05788351 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,475E-03 0,05757397 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,475E-03 0,05726773 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,475E-03 0,05696472 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,475E-03 0,05666491 ! female meiosis GO:0007143 7 5 0,000 4,475E-03 0,05636823 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,475E-03 0,05607465 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,475E-03 0,05578411 ! cobalt ion transport GO:0006824 11 5 0,000 4,475E-03 0,05549656 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,475E-03 0,05521196 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,475E-03 0,05493027 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,475E-03 0,05465143 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,475E-03 0,05437542 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,475E-03 0,05410217 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,475E-03 0,05383166 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,475E-03 0,05356384 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,475E-03 0,05329867 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,475E-03 0,05303612 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,475E-03 0,05277614 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,475E-03 0,05251869 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,475E-03 0,05226375 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,475E-03 0,05201127 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,475E-03 0,05176121 ! negative chemotaxis GO:0050919 14 5 0,000 4,475E-03 0,05151355 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,475E-03 0,05126825 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,475E-03 0,05102527 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,475E-03 0,05078459 ! behavioral response to pain GO:0048266 9 5 0,000 4,475E-03 0,05054616 ! clathrin coat assembly GO:0048268 14 5 0,000 4,475E-03 0,05030996 ! Notch receptor processing GO:0007220 8 5 0,000 4,475E-03 0,05007596 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,475E-03 0,04984413 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,475E-03 0,04961443 ! micturition GO:0060073 9 5 0,000 4,475E-03 0,04938685 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,475E-03 0,04916133 ! copulation GO:0007620 9 5 0,000 4,475E-03 0,04893787 ! glial cell fate commitment GO:0021781 13 5 0,000 4,475E-03 0,04871644 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,475E-03 0,04849699 ! spermidine metabolic process GO:0008216 7 5 0,000 4,475E-03 0,04827952 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,475E-03 0,04806398 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,475E-03 0,04785037 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,475E-03 0,04763864 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,475E-03 0,04742878 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,475E-03 0,04722076 ! grooming behavior GO:0007625 6 5 0,000 4,475E-03 0,04701455 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,475E-03 0,04681014 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,475E-03 0,0466075 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,475E-03 0,0464066 ! response to protozoan GO:0001562 10 5 0,000 4,475E-03 0,04620743 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,475E-03 0,04600997 ! lymph vessel development GO:0001945 10 5 0,000 4,475E-03 0,04581418 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,475E-03 0,04562005 ! endochondral ossification GO:0001958 16 5 0,000 4,475E-03 0,04542756 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,475E-03 0,04523669 ! parathyroid gland development GO:0060017 13 5 0,000 4,475E-03 0,04504742 ! anagen GO:0042640 6 5 0,000 4,475E-03 0,04485972 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,475E-03 0,04467358 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,475E-03 0,04448898 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,475E-03 0,04430589 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,475E-03 0,04412431 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,475E-03 0,04394421 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,475E-03 0,04376558 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,475E-03 0,04358839 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,475E-03 0,04341263 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,475E-03 0,04323828 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,475E-03 0,04306533 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,475E-03 0,04289375 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,475E-03 0,04272354 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,475E-03 0,04255467 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,475E-03 0,04238714 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,475E-03 0,04222091 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,475E-03 0,04205599 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,475E-03 0,04189234 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,475E-03 0,04172997 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,475E-03 0,04156885 ! histidine catabolic process GO:0006548 6 5 0,000 4,475E-03 0,04140897 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,475E-03 0,04125032 ! microvillus organization GO:0032528 7 5 0,000 4,475E-03 0,04109287 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,475E-03 0,04093662 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,475E-03 0,04078156 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,475E-03 0,04062767 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,475E-03 0,04047493 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,475E-03 0,04032334 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,475E-03 0,04017288 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,475E-03 0,04002354 ! polyol catabolic process GO:0046174 7 5 0,000 4,475E-03 0,0398753 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,475E-03 0,03972816 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,475E-03 0,0395821 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,475E-03 0,03943711 ! mitochondrial fission GO:0000266 8 5 0,000 4,475E-03 0,03929318 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,475E-03 0,0391503 ! mRNA transcription GO:0009299 9 5 0,000 4,475E-03 0,03900845 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,475E-03 0,03886763 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,475E-03 0,03872781 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,475E-03 0,038589 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,475E-03 0,03845119 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,475E-03 0,03831435 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,475E-03 0,03817848 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,475E-03 0,03804358 ! response to food GO:0032094 6 5 0,000 4,475E-03 0,03790962 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,475E-03 0,0377766 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,475E-03 0,03764452 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,475E-03 0,03751335 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,475E-03 0,0373831 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,475E-03 0,03725374 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,475E-03 0,03712528 ! forebrain neuron development GO:0021884 13 5 0,000 4,475E-03 0,03699771 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,475E-03 0,036871 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,475E-03 0,03674516 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,475E-03 0,03662018 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,475E-03 0,03649604 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,475E-03 0,03637274 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,475E-03 0,03625028 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,475E-03 0,03612863 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,475E-03 0,0360078 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,475E-03 0,03588777 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,475E-03 0,03576855 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,475E-03 0,03565011 ! basic amino acid transport GO:0015802 11 5 0,000 4,475E-03 0,03553245 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,475E-03 0,03541557 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,475E-03 0,03529945 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,475E-03 0,03518409 ! depyrimidination GO:0045008 10 5 0,000 4,475E-03 0,03506949 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,475E-03 0,03495562 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,475E-03 0,0348425 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,475E-03 0,0347301 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,475E-03 0,03461843 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,475E-03 0,03450748 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,475E-03 0,03439723 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,475E-03 0,03428768 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,475E-03 0,03417883 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,475E-03 0,03407067 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,475E-03 0,03396319 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,475E-03 0,03385639 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,475E-03 0,03375026 ! response to arsenic GO:0046685 10 5 0,000 4,475E-03 0,03364479 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,475E-03 0,03353998 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,475E-03 0,03343581 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,475E-03 0,0333323 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,475E-03 0,03322942 ! response to cadmium ion GO:0046686 7 5 0,000 4,475E-03 0,03312718 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,475E-03 0,03302556 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,475E-03 0,03292456 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,475E-03 0,03282418 ! decidualization GO:0046697 11 5 0,000 4,475E-03 0,03272441 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,475E-03 0,03262525 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,475E-03 0,03252668 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,475E-03 0,03242871 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,475E-03 0,03233133 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,475E-03 0,03223453 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,475E-03 0,03213831 ! neural tube patterning GO:0021532 7 5 0,000 4,475E-03 0,03204266 ! embryonic cleavage GO:0040016 6 5 0,000 4,475E-03 0,03194757 ! peroxisome fission GO:0016559 5 5 0,000 4,475E-03 0,03185305 ! histone demethylation GO:0016577 10 5 0,000 4,475E-03 0,03175909 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,475E-03 0,03166568 ! mitotic recombination GO:0006312 9 5 0,000 4,475E-03 0,03157282 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,475E-03 0,0314805 ! metaphase plate congression GO:0051310 7 5 0,000 4,475E-03 0,03138872 ! regulation of sterol transport GO:0032371 7 5 0,000 4,475E-03 0,03129748 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,475E-03 0,03120676 ! enteric nervous system development GO:0048484 8 5 0,000 4,475E-03 0,03111657 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,475E-03 0,03102689 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,475E-03 0,03093774 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,475E-03 0,03084909 ! muscle cell proliferation GO:0033002 11 5 0,000 4,475E-03 0,03076095 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,475E-03 0,03067331 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,475E-03 0,03058617 ! plasminogen activation GO:0031639 5 5 0,000 4,475E-03 0,03049952 ! B cell homeostasis GO:0001782 13 5 0,000 4,475E-03 0,03041337 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,475E-03 0,0303277 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,475E-03 0,03024251 ! metaphase GO:0051323 8 5 0,000 4,475E-03 0,03015779 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,475E-03 0,03007355 ! cellular response to nutrient GO:0031670 8 5 0,000 4,475E-03 0,02998978 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,475E-03 0,02990648 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,475E-03 0,02982364 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,475E-03 0,02974125 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,475E-03 0,02965932 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,475E-03 0,02957784 ! response to redox state GO:0051775 5 5 0,000 4,475E-03 0,0294968 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,475E-03 0,02941621 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,475E-03 0,02933606 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,475E-03 0,02925634 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,475E-03 0,02917705 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,475E-03 0,0290982 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,475E-03 0,02901976 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,475E-03 0,02894175 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,475E-03 0,02886416 ! striatum development GO:0021756 9 5 0,000 4,475E-03 0,02878698 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,475E-03 0,02871022 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 4,475E-03 0,02863386 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,475E-03 0,02855791 ! glial cell migration GO:0008347 11 5 0,000 4,475E-03 0,02848236 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,475E-03 0,02840721 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,475E-03 0,02833245 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,475E-03 0,02825809 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,475E-03 0,02818412 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,475E-03 0,02811053 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,475E-03 0,02803732 ! neuroprotection GO:0043526 6 5 0,000 4,475E-03 0,0279645 ! neural plate development GO:0001840 8 5 0,000 4,475E-03 0,02789205 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,475E-03 0,02781998 ! regulation of sensory perception GO:0051931 7 5 0,000 4,475E-03 0,02774828 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,475E-03 0,02767695 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,475E-03 0,02760598 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,475E-03 0,02753538 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,475E-03 0,02746513 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,475E-03 0,02739525 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,475E-03 0,02732572 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,475E-03 0,02725654 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,475E-03 0,02718771 ! spindle assembly GO:0051225 6 5 0,000 4,475E-03 0,02711922 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,475E-03 0,02705109 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,475E-03 0,02698329 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,475E-03 0,02691583 ! drug metabolic process GO:0017144 6 5 0,000 4,475E-03 0,02684871 ! stem cell division GO:0017145 11 5 0,000 4,475E-03 0,02678192 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,475E-03 0,02671546 ! organ regeneration GO:0031100 7 5 0,000 4,475E-03 0,02664934 ! carnitine metabolic process GO:0009437 7 5 0,000 4,475E-03 0,02658354 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,475E-03 0,02651806 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,475E-03 0,0264529 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,367E-03 0,03165202 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,367E-03 0,03157463 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,367E-03 0,03149762 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,367E-03 0,03142098 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,367E-03 0,03134472 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,367E-03 0,03126882 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,367E-03 0,0311933 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,367E-03 0,03111813 ! sleep GO:0030431 13 6 0,000 5,367E-03 0,03104333 ! response to oxygen radical GO:0000305 11 6 0,000 5,367E-03 0,03096888 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,367E-03 0,0308948 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,367E-03 0,03082106 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,367E-03 0,03074768 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,367E-03 0,03067464 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,367E-03 0,03060195 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,367E-03 0,03052961 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,367E-03 0,03045761 ! forebrain regionalization GO:0021871 8 6 0,000 5,367E-03 0,03038594 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,367E-03 0,03031461 ! male meiosis GO:0007140 7 6 0,000 5,367E-03 0,03024362 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,367E-03 0,03017295 ! response to zinc ion GO:0010043 9 6 0,000 5,367E-03 0,03010262 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,367E-03 0,03003262 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,367E-03 0,02996293 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,367E-03 0,02989358 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,367E-03 0,02982454 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,367E-03 0,02975582 ! malate metabolic process GO:0006108 11 6 0,000 5,367E-03 0,02968741 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,367E-03 0,02961932 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,367E-03 0,02955154 ! protein refolding GO:0042026 15 6 0,000 5,367E-03 0,02948407 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,367E-03 0,02941691 ! opsonization GO:0008228 8 6 0,000 5,367E-03 0,02935006 ! mating behavior GO:0007617 7 6 0,000 5,367E-03 0,0292835 ! neuron remodeling GO:0016322 15 6 0,000 5,367E-03 0,02921725 ! erythrocyte maturation GO:0043249 7 6 0,000 5,367E-03 0,0291513 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,367E-03 0,02908564 ! equilibrioception GO:0050957 14 6 0,000 5,367E-03 0,02902028 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,367E-03 0,02895521 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,367E-03 0,02889044 ! photoreceptor cell development GO:0042461 10 6 0,000 5,367E-03 0,02882595 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,367E-03 0,02876175 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,367E-03 0,02869783 ! response to interferon-gamma GO:0034341 15 6 0,000 5,367E-03 0,0286342 ! toxin metabolic process GO:0009404 11 6 0,000 5,367E-03 0,02857085 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,367E-03 0,02850778 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,367E-03 0,02844499 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,367E-03 0,02838247 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,367E-03 0,02832023 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,367E-03 0,02825826 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,367E-03 0,02819656 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,367E-03 0,02813513 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,367E-03 0,02807397 ! thymic T cell selection GO:0045061 12 6 0,000 5,367E-03 0,02801307 ! protein lipoylation GO:0009249 10 6 0,000 5,367E-03 0,02795243 ! cysteine metabolic process GO:0006534 10 6 0,000 5,367E-03 0,02789206 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,367E-03 0,02783195 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,367E-03 0,0277721 ! glutamate catabolic process GO:0006538 10 6 0,000 5,367E-03 0,0277125 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,367E-03 0,02765316 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,367E-03 0,02759407 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,367E-03 0,02753523 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,367E-03 0,02747665 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,367E-03 0,02741831 ! hyperosmotic response GO:0006972 9 6 0,000 5,367E-03 0,02736022 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,367E-03 0,02730238 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,367E-03 0,02724478 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,367E-03 0,02718742 ! urea metabolic process GO:0019627 7 6 0,000 5,367E-03 0,0271303 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,367E-03 0,02707343 ! neutrophil activation GO:0042119 8 6 0,000 5,367E-03 0,02701679 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,367E-03 0,02696039 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,367E-03 0,02690422 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,367E-03 0,02684828 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,367E-03 0,02679258 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,367E-03 0,02673711 ! neuron apoptosis GO:0051402 9 6 0,000 5,367E-03 0,02668187 ! nucleoside salvage GO:0043174 9 6 0,000 5,367E-03 0,02662685 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,367E-03 0,02657207 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,367E-03 0,0265175 ! T cell mediated immunity GO:0002456 16 6 0,000 5,367E-03 0,02646317 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,367E-03 0,02640905 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,367E-03 0,02635515 ! carnitine transport GO:0015879 10 6 0,000 5,367E-03 0,02630148 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,367E-03 0,02624802 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,367E-03 0,02619478 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,367E-03 0,02614175 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,367E-03 0,02608894 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,367E-03 0,02603634 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,367E-03 0,02598395 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,367E-03 0,02593178 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,367E-03 0,02587981 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,367E-03 0,02582805 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,367E-03 0,0257765 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,367E-03 0,02572515 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,367E-03 0,02567401 ! neural nucleus development GO:0048857 14 6 0,000 5,367E-03 0,02562306 ! response to UV-C GO:0010225 11 6 0,000 5,367E-03 0,02557233 ! astrocyte development GO:0014002 15 6 0,000 5,367E-03 0,02552179 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,367E-03 0,02547145 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,367E-03 0,02542131 ! interaction with symbiont GO:0051702 13 6 0,000 5,367E-03 0,02537136 ! regulation of dendrite development GO:0050773 16 6 0,000 5,367E-03 0,02532162 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,367E-03 0,02527206 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,367E-03 0,0252227 ! response to copper ion GO:0046688 10 6 0,000 5,367E-03 0,02517354 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,367E-03 0,02512456 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,367E-03 0,02507578 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,367E-03 0,02502718 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,367E-03 0,02497877 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,367E-03 0,02493055 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,367E-03 0,02488251 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,367E-03 0,02483466 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,367E-03 0,024787 ! hair follicle maturation GO:0048820 7 6 0,000 5,367E-03 0,02473951 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,367E-03 0,02469221 ! Schwann cell development GO:0014044 15 6 0,000 5,367E-03 0,02464509 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,367E-03 0,02459814 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,367E-03 0,02455138 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,367E-03 0,02450479 ! subpallium development GO:0021544 10 6 0,000 5,367E-03 0,02445838 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,367E-03 0,02441214 ! histone ubiquitination GO:0016574 8 6 0,000 5,367E-03 0,02436608 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,367E-03 0,0243202 ! maintenance of organ identity GO:0048496 9 6 0,000 5,367E-03 0,02427448 ! G2 phase GO:0051319 16 6 0,000 5,367E-03 0,02422894 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,367E-03 0,02418357 ! establishment of planar polarity GO:0001736 7 6 0,000 5,367E-03 0,02413836 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,367E-03 0,02409333 ! membrane to membrane docking GO:0022614 14 6 0,000 5,367E-03 0,02404846 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,367E-03 0,02400376 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,367E-03 0,02395923 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,367E-03 0,02391486 ! receptor internalization GO:0031623 10 6 0,000 5,367E-03 0,02387066 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,367E-03 0,02382661 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,367E-03 0,02378273 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,367E-03 0,02373902 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,367E-03 0,02369546 ! protein deubiquitination GO:0016579 14 6 0,000 5,367E-03 0,02365206 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,367E-03 0,02360882 ! protein destabilization GO:0031648 9 6 0,000 5,367E-03 0,02356574 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,367E-03 0,02352281 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,367E-03 0,02348004 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,367E-03 0,02343743 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,367E-03 0,02339497 ! progesterone metabolic process GO:0042448 10 6 0,000 5,367E-03 0,02335267 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,367E-03 0,02331051 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,367E-03 0,02326851 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,367E-03 0,02322666 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,367E-03 0,02318496 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,367E-03 0,02314341 ! determination of adult lifespan GO:0008340 15 6 0,000 5,367E-03 0,02310201 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,367E-03 0,02306076 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,367E-03 0,02301965 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,367E-03 0,02297869 ! catecholamine transport GO:0051937 9 6 0,000 5,367E-03 0,02293788 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,367E-03 0,02289721 ! sensory cilium assembly GO:0035058 10 6 0,000 5,367E-03 0,02285668 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,367E-03 0,0228163 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,367E-03 0,02277606 ! maternal placenta development GO:0001893 12 6 0,000 5,367E-03 0,02273596 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,367E-03 0,022696 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,367E-03 0,02265618 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,367E-03 0,02261651 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,367E-03 0,02257697 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,367E-03 0,02253756 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,367E-03 0,0224983 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,367E-03 0,02245917 ! tRNA transcription GO:0009304 14 7 0,000 6,259E-03 0,02614559 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,259E-03 0,02610028 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,259E-03 0,02605513 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,259E-03 0,02601012 ! regulation of helicase activity GO:0051095 15 7 0,000 6,259E-03 0,02596528 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,259E-03 0,02592059 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,259E-03 0,02587605 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,259E-03 0,02583167 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,259E-03 0,02578744 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,259E-03 0,02574335 ! prostate gland development GO:0030850 13 7 0,000 6,259E-03 0,02569942 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,259E-03 0,02565564 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,259E-03 0,02561201 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,259E-03 0,02556853 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,259E-03 0,02552519 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,259E-03 0,025482 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,259E-03 0,02543896 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,259E-03 0,02539606 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,259E-03 0,0253533 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,259E-03 0,02531069 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,259E-03 0,02526823 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,259E-03 0,0252259 ! glycolipid transport GO:0046836 10 7 0,000 6,259E-03 0,02518372 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,259E-03 0,02514167 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 6,259E-03 0,02509977 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,259E-03 0,02505801 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,259E-03 0,02501638 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,259E-03 0,0249749 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,259E-03 0,02493355 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,259E-03 0,02489233 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,259E-03 0,02485126 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,259E-03 0,02481032 ! mRNA stabilization GO:0048255 18 7 0,000 6,259E-03 0,02476951 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,259E-03 0,02472884 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,259E-03 0,0246883 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,259E-03 0,02464789 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,259E-03 0,02460762 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,259E-03 0,02456748 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,259E-03 0,02452746 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,259E-03 0,02448758 ! lipoprotein transport GO:0042953 14 7 0,000 6,259E-03 0,02444783 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,259E-03 0,0244082 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,259E-03 0,02436871 ! rhythmic behavior GO:0007622 15 7 0,000 6,259E-03 0,02432934 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,259E-03 0,0242901 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,259E-03 0,02425099 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,259E-03 0,024212 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,259E-03 0,02417313 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,259E-03 0,02413439 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,259E-03 0,02409578 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,259E-03 0,02405729 ! mechanosensory behavior GO:0007638 14 7 0,000 6,259E-03 0,02401892 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,259E-03 0,02398067 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,259E-03 0,02394255 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,259E-03 0,02390454 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,259E-03 0,02386666 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,259E-03 0,0238289 ! spinal cord patterning GO:0021511 13 7 0,000 6,259E-03 0,02379125 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,259E-03 0,02375373 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,259E-03 0,02371632 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,259E-03 0,02367903 ! adrenal gland development GO:0030325 17 7 0,000 6,259E-03 0,02364186 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,259E-03 0,0236048 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,259E-03 0,02356786 ! ovulation GO:0030728 9 7 0,000 6,259E-03 0,02353103 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,259E-03 0,02349433 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,259E-03 0,02345773 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,259E-03 0,02342125 ! microtubule nucleation GO:0007020 20 7 0,000 6,259E-03 0,02338488 ! proline biosynthetic process GO:0006561 10 7 0,000 6,259E-03 0,02334862 ! thyroid hormone generation GO:0006590 13 7 0,000 6,259E-03 0,02331248 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,259E-03 0,02327645 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,259E-03 0,02324053 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,259E-03 0,02320472 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,259E-03 0,02316902 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,259E-03 0,02313343 ! galactose metabolic process GO:0006012 13 7 0,000 6,259E-03 0,02309795 ! vesicle fusion GO:0006906 17 7 0,000 6,259E-03 0,02306258 ! response to dietary excess GO:0002021 8 7 0,000 6,259E-03 0,02302731 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,259E-03 0,02299216 ! intracellular pH reduction GO:0051452 11 7 0,000 6,259E-03 0,02295711 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,259E-03 0,02292216 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,259E-03 0,02288733 ! organ growth GO:0035265 15 7 0,000 6,259E-03 0,0228526 ! purine salvage GO:0043101 10 7 0,000 6,259E-03 0,02281797 ! nucleoside transport GO:0015858 8 7 0,000 6,259E-03 0,02278345 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,259E-03 0,02274904 ! parturition GO:0007567 14 7 0,000 6,259E-03 0,02271472 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,259E-03 0,02268052 ! rRNA modification GO:0000154 14 7 0,000 6,259E-03 0,02264641 ! spindle checkpoint GO:0031577 15 7 0,000 6,259E-03 0,02261241 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,259E-03 0,0225785 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,259E-03 0,0225447 ! macrophage differentiation GO:0030225 11 7 0,000 6,259E-03 0,022511 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,259E-03 0,02247741 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,259E-03 0,02244391 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,259E-03 0,02241051 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,259E-03 0,02237721 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,259E-03 0,02234401 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,259E-03 0,02231091 ! fibrinolysis GO:0042730 10 7 0,000 6,259E-03 0,0222779 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,259E-03 0,022245 ! eating behavior GO:0042755 7 7 0,000 6,259E-03 0,02221219 ! B cell lineage commitment GO:0002326 21 7 0,000 6,259E-03 0,02217947 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,259E-03 0,02214686 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,259E-03 0,02211434 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,259E-03 0,02208191 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,259E-03 0,02204958 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,259E-03 0,02201734 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,259E-03 0,0219852 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,259E-03 0,02195315 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,259E-03 0,0219212 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,259E-03 0,02188933 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,259E-03 0,02185757 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,259E-03 0,02182589 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,259E-03 0,0217943 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,259E-03 0,02176281 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,259E-03 0,0217314 ! regulation of meiosis GO:0040020 12 7 0,000 6,259E-03 0,02170009 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,259E-03 0,02166887 ! T cell lineage commitment GO:0002360 16 7 0,000 6,259E-03 0,02163773 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,259E-03 0,02160669 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,259E-03 0,02157573 ! oxygen homeostasis GO:0032364 12 7 0,000 6,259E-03 0,02154487 ! transcription termination GO:0006353 13 7 0,000 6,259E-03 0,02151409 ! response to tumor cell GO:0002347 13 7 0,000 6,259E-03 0,0214834 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,259E-03 0,0214528 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,259E-03 0,02142228 ! anaphase GO:0051322 17 7 0,000 6,259E-03 0,02139185 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,259E-03 0,02136151 ! axonal fasciculation GO:0007413 18 7 0,000 6,259E-03 0,02133125 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,259E-03 0,02130108 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,259E-03 0,02127099 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,259E-03 0,02124099 ! diuresis GO:0030146 12 7 0,000 6,259E-03 0,02121107 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,259E-03 0,02118124 ! thiamin metabolic process GO:0006772 7 7 0,000 6,259E-03 0,02115149 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,259E-03 0,02112183 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,259E-03 0,02109224 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,259E-03 0,02106274 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,259E-03 0,02103333 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,259E-03 0,02100399 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,259E-03 0,02097474 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,259E-03 0,02094557 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,259E-03 0,02091648 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,259E-03 0,02088747 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,259E-03 0,02085854 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,259E-03 0,02082969 ! lymph node development GO:0048535 10 7 0,000 6,259E-03 0,02080091 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,259E-03 0,02077222 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,259E-03 0,02074361 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,259E-03 0,02071508 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,259E-03 0,02068662 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,259E-03 0,02065825 ! adult feeding behavior GO:0008343 9 7 0,000 6,259E-03 0,02062995 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,259E-03 0,02060173 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,259E-03 0,02057358 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,259E-03 0,02054551 ! muscle adaptation GO:0043500 14 7 0,000 6,259E-03 0,02051752 ! embryonic heart tube development GO:0035050 10 7 0,000 6,259E-03 0,02048961 ! retina homeostasis GO:0001895 12 7 0,000 6,259E-03 0,02046177 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,259E-03 0,02043401 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,259E-03 0,02040632 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,259E-03 0,0203787 ! protein prenylation GO:0018342 18 7 0,000 6,259E-03 0,02035117 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,259E-03 0,0203237 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,259E-03 0,02029631 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,259E-03 0,02026899 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 7,15E-03 0,02312345 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 7,15E-03 0,02309241 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 7,15E-03 0,02306146 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 7,15E-03 0,02303059 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 7,15E-03 0,0229998 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,15E-03 0,02296909 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,15E-03 0,02293846 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 7,15E-03 0,02290792 ! neutral lipid catabolic process GO:0046461 13 8 0,000 7,15E-03 0,02287746 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 7,15E-03 0,02284707 ! meiotic prophase I GO:0007128 13 8 0,000 7,15E-03 0,02281677 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,15E-03 0,02278655 ! oligopeptide transport GO:0006857 15 8 0,000 7,15E-03 0,02275641 ! UTP metabolic process GO:0046051 8 8 0,000 7,15E-03 0,02272635 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 7,15E-03 0,02269637 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 7,15E-03 0,02266647 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 7,15E-03 0,02263664 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,15E-03 0,0226069 ! succinate metabolic process GO:0006105 14 8 0,000 7,15E-03 0,02257723 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,15E-03 0,02254764 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,15E-03 0,02251812 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 7,15E-03 0,02248869 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,15E-03 0,02245933 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 7,15E-03 0,02243005 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,15E-03 0,02240084 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,15E-03 0,02237171 ! ganglioside metabolic process GO:0001573 19 8 0,000 7,15E-03 0,02234266 ! reflex GO:0060004 16 8 0,000 7,15E-03 0,02231368 ! negative regulation of endocytosis GO:0045806 11 8 0,000 7,15E-03 0,02228478 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 7,15E-03 0,02225595 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,15E-03 0,02222719 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 7,15E-03 0,02219851 ! glycerolipid catabolic process GO:0046503 13 8 0,000 7,15E-03 0,02216991 ! hemoglobin metabolic process GO:0020027 13 8 0,000 7,15E-03 0,02214137 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,15E-03 0,02211291 ! pigment granule organization GO:0048753 16 8 0,000 7,15E-03 0,02208453 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,15E-03 0,02205621 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 7,15E-03 0,02202797 ! astrocyte differentiation GO:0048708 18 8 0,000 7,15E-03 0,0219998 ! histidine metabolic process GO:0006547 16 8 0,000 7,15E-03 0,02197171 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,15E-03 0,02194368 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 7,15E-03 0,02191573 ! glycine catabolic process GO:0006546 13 8 0,000 7,15E-03 0,02188785 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 7,15E-03 0,02186003 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 7,15E-03 0,02183229 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 7,15E-03 0,02180462 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 7,15E-03 0,02177702 ! regulation of pigmentation during development GO:0048070 24 8 0,000 7,15E-03 0,02174949 ! melanin metabolic process GO:0006582 15 8 0,000 7,15E-03 0,02172203 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 7,15E-03 0,02169464 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,15E-03 0,02166731 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,15E-03 0,02164006 ! macrophage activation GO:0042116 12 8 0,000 7,15E-03 0,02161287 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,15E-03 0,02158576 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,15E-03 0,02155871 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 7,15E-03 0,02153172 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,15E-03 0,02150481 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,15E-03 0,02147796 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 7,15E-03 0,02145118 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,15E-03 0,02142447 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 7,15E-03 0,02139782 ! osteoblast development GO:0002076 16 8 0,000 7,15E-03 0,02137124 ! positive regulation of vasodilation GO:0045909 13 8 0,000 7,15E-03 0,02134472 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,15E-03 0,02131827 ! negative regulation of translational initiation GO:0045947 10 8 0,000 7,15E-03 0,02129189 ! Schwann cell differentiation GO:0014037 19 8 0,000 7,15E-03 0,02126557 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 7,15E-03 0,02123932 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,15E-03 0,02121313 ! response to UV-B GO:0010224 16 8 0,000 7,15E-03 0,021187 ! protein targeting to vacuole GO:0006623 12 8 0,000 7,15E-03 0,02116094 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,15E-03 0,02113495 ! intermediate filament organization GO:0045109 12 8 0,000 7,15E-03 0,02110901 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 7,15E-03 0,02108315 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 7,15E-03 0,02105734 ! cellular extravasation GO:0045123 12 8 0,000 7,15E-03 0,0210316 ! cardiac muscle cell development GO:0055013 13 8 0,000 7,15E-03 0,02100592 ! regulation of circadian rhythm GO:0042752 16 8 0,000 7,15E-03 0,0209803 ! response to antibiotic GO:0046677 11 8 0,000 7,15E-03 0,02095475 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 7,15E-03 0,02092925 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 7,15E-03 0,02090382 ! DNA topological change GO:0006265 12 8 0,000 7,15E-03 0,02087846 ! response to tropane GO:0014073 15 8 0,000 7,15E-03 0,02085315 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 7,15E-03 0,0208279 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 7,15E-03 0,02080272 ! melanosome transport GO:0032402 13 8 0,000 7,15E-03 0,02077759 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 7,15E-03 0,02075253 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 7,15E-03 0,02072753 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,15E-03 0,02070258 ! mast cell activation GO:0045576 14 8 0,000 7,15E-03 0,0206777 ! multicellular organismal aging GO:0010259 18 8 0,000 7,15E-03 0,02065288 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 7,15E-03 0,02062811 ! dendrite morphogenesis GO:0048813 13 8 0,000 7,15E-03 0,02060341 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 7,15E-03 0,02057876 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,15E-03 0,02055418 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 7,15E-03 0,02052965 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,15E-03 0,02050518 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,15E-03 0,02048077 ! establishment of chromosome localization GO:0051303 12 8 0,000 7,15E-03 0,02045642 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 7,15E-03 0,02043212 ! intracellular lipid transport GO:0032365 13 8 0,000 7,15E-03 0,02040789 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,15E-03 0,02038371 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,15E-03 0,02035958 ! regulation of macrophage activation GO:0043030 15 8 0,000 7,15E-03 0,02033552 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 7,15E-03 0,02031151 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,15E-03 0,02028756 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 7,15E-03 0,02026366 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 7,15E-03 0,02023982 ! hormone catabolic process GO:0042447 17 8 0,000 7,15E-03 0,02021604 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,15E-03 0,02019231 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 7,15E-03 0,02016864 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 7,15E-03 0,02014502 ! ATP catabolic process GO:0006200 11 8 0,000 7,15E-03 0,02012146 ! blastocyst growth GO:0001832 19 8 0,000 7,15E-03 0,02009795 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,15E-03 0,0200745 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,15E-03 0,0200511 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 7,15E-03 0,02002776 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,15E-03 0,02000447 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,15E-03 0,01998124 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 7,15E-03 0,01995806 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 7,15E-03 0,01993493 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 7,15E-03 0,01991186 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 7,15E-03 0,01988884 ! amino sugar catabolic process GO:0046348 10 8 0,000 7,15E-03 0,01986587 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 7,15E-03 0,01984296 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,15E-03 0,0198201 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,15E-03 0,01979729 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,15E-03 0,01977454 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,15E-03 0,01975183 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,15E-03 0,01972918 ! NAD biosynthetic process GO:0009435 13 8 0,000 7,15E-03 0,01970658 ! regulation of developmental growth GO:0048638 15 9 0,000 8,041E-03 0,02213499 ! axon extension GO:0048675 15 9 0,000 8,041E-03 0,02210969 ! autophagic vacuole formation GO:0000045 15 9 0,000 8,041E-03 0,02208445 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,041E-03 0,02205927 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 8,041E-03 0,02203415 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 8,041E-03 0,02200908 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,041E-03 0,02198407 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 8,041E-03 0,02195912 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 8,041E-03 0,02193422 ! cell proliferation in forebrain GO:0021846 15 9 0,000 8,041E-03 0,02190938 ! phosphate transport GO:0006817 19 9 0,000 8,041E-03 0,02188459 ! reproductive behavior GO:0019098 19 9 0,000 8,041E-03 0,02185987 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,041E-03 0,02183519 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 8,041E-03 0,02181058 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,041E-03 0,02178601 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 8,041E-03 0,02176151 ! GTP metabolic process GO:0046039 9 9 0,000 8,041E-03 0,02173706 ! RNA methylation GO:0001510 15 9 0,000 8,041E-03 0,02171266 ! elastic fiber assembly GO:0048251 15 9 0,000 8,041E-03 0,02168832 ! induction of positive chemotaxis GO:0050930 15 9 0,000 8,041E-03 0,02166403 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 8,041E-03 0,0216398 ! artery development GO:0060840 24 9 0,000 8,041E-03 0,02161562 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 8,041E-03 0,0215915 ! regulation of glycolysis GO:0006110 21 9 0,000 8,041E-03 0,02156743 ! cerebral cortex cell migration GO:0021795 15 9 0,000 8,041E-03 0,02154341 ! keratinocyte proliferation GO:0043616 14 9 0,000 8,041E-03 0,02151944 ! chemosensory behavior GO:0007635 20 9 0,000 8,041E-03 0,02149553 ! microtubule bundle formation GO:0001578 21 9 0,000 8,041E-03 0,02147168 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,041E-03 0,02144787 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 8,041E-03 0,02142412 ! leukocyte degranulation GO:0043299 16 9 0,000 8,041E-03 0,02140042 ! bile acid and bile salt transport GO:0015721 13 9 0,000 8,041E-03 0,02137677 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 8,041E-03 0,02135318 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,041E-03 0,02132964 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,041E-03 0,02130615 ! protein targeting to ER GO:0045047 22 9 0,000 8,041E-03 0,02128271 ! ceramide biosynthetic process GO:0046513 19 9 0,000 8,041E-03 0,02125932 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 8,041E-03 0,02123598 ! T cell selection GO:0045058 23 9 0,000 8,041E-03 0,0212127 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 8,041E-03 0,02118946 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 8,041E-03 0,02116628 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,041E-03 0,02114315 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 8,041E-03 0,02112007 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 8,041E-03 0,02109703 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,041E-03 0,02107405 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,041E-03 0,02105112 ! mannose metabolic process GO:0006013 13 9 0,000 8,041E-03 0,02102824 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 8,041E-03 0,02100541 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 8,041E-03 0,02098263 ! Rac protein signal transduction GO:0016601 17 9 0,000 8,041E-03 0,02095989 ! receptor clustering GO:0043113 18 9 0,000 8,041E-03 0,02093721 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 8,041E-03 0,02091457 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,041E-03 0,02089199 ! ruffle organization GO:0031529 15 9 0,000 8,041E-03 0,02086945 ! retinol metabolic process GO:0042572 18 9 0,000 8,041E-03 0,02084696 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 8,041E-03 0,02082452 ! behavioral fear response GO:0001662 22 9 0,000 8,041E-03 0,02080213 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 8,041E-03 0,02077979 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 8,041E-03 0,02075749 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 8,041E-03 0,02073524 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 8,041E-03 0,02071304 ! protein heterooligomerization GO:0051291 16 9 0,000 8,041E-03 0,02069089 ! oligodendrocyte development GO:0014003 10 9 0,000 8,041E-03 0,02066878 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 8,041E-03 0,02064672 ! segment specification GO:0007379 13 9 0,000 8,041E-03 0,02062471 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,041E-03 0,02060275 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 8,041E-03 0,02058083 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,041E-03 0,02055896 ! response to amine stimulus GO:0014075 13 9 0,000 8,041E-03 0,02053713 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,041E-03 0,02051536 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 8,041E-03 0,02049362 ! erythrocyte development GO:0048821 15 9 0,000 8,041E-03 0,02047194 ! gas homeostasis GO:0033483 16 9 0,000 8,041E-03 0,0204503 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,041E-03 0,0204287 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 8,041E-03 0,02040715 ! renal water homeostasis GO:0003091 14 9 0,000 8,041E-03 0,02038565 ! postreplication repair GO:0006301 22 9 0,000 8,041E-03 0,02036419 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 8,041E-03 0,02034278 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 8,041E-03 0,02032141 ! icosanoid secretion GO:0032309 15 9 0,000 8,041E-03 0,02030008 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,041E-03 0,02027881 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 8,041E-03 0,02025757 ! regulation of cell division GO:0051302 15 9 0,000 8,041E-03 0,02023638 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 8,041E-03 0,02021524 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,041E-03 0,02019413 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,041E-03 0,02017308 ! sterol catabolic process GO:0016127 11 9 0,000 8,041E-03 0,02015206 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,041E-03 0,02013109 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 8,041E-03 0,02011017 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 8,041E-03 0,02008928 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 8,041E-03 0,02006844 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 8,041E-03 0,02004765 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 8,041E-03 0,0200269 ! musculoskeletal movement GO:0050881 14 9 0,000 8,041E-03 0,02000618 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 8,041E-03 0,01998552 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 8,041E-03 0,01996489 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,041E-03 0,01994431 ! purine base metabolic process GO:0006144 21 9 0,000 8,041E-03 0,01992377 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 8,041E-03 0,01990327 ! pigment granule transport GO:0051904 17 9 0,000 8,041E-03 0,01988282 ! regulation of fibrinolysis GO:0051917 16 9 0,000 8,041E-03 0,0198624 ! regulation of telomere maintenance GO:0032204 14 9 0,000 8,041E-03 0,01984203 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 8,041E-03 0,0198217 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,041E-03 0,01980141 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,041E-03 0,01978117 ! mitochondrion localization GO:0051646 15 9 0,000 8,041E-03 0,01976096 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,93E-03 0,02192476 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,93E-03 0,02190241 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 8,93E-03 0,02188011 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,93E-03 0,02185785 ! synapsis GO:0007129 13 10 0,000 8,93E-03 0,02183563 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,93E-03 0,02181347 ! N-glycan processing GO:0006491 20 10 0,000 8,93E-03 0,02179134 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 8,93E-03 0,02176926 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,93E-03 0,02174723 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,93E-03 0,02172524 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,93E-03 0,0217033 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,93E-03 0,0216814 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,93E-03 0,02165954 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,93E-03 0,02163773 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,93E-03 0,02161596 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,93E-03 0,02159424 ! androgen metabolic process GO:0008209 17 10 0,000 8,93E-03 0,02157255 ! phospholipid efflux GO:0033700 16 10 0,000 8,93E-03 0,02155092 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,93E-03 0,02152932 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,93E-03 0,02150777 ! lung alveolus development GO:0048286 26 10 0,000 8,93E-03 0,02148626 ! pathogenesis GO:0009405 13 10 0,000 8,93E-03 0,0214648 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,93E-03 0,02144338 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,93E-03 0,021422 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,93E-03 0,02140066 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,93E-03 0,02137937 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,93E-03 0,02135812 ! endoderm development GO:0007492 16 10 0,000 8,93E-03 0,02133691 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,93E-03 0,02131574 ! arginine catabolic process GO:0006527 13 10 0,000 8,93E-03 0,02129461 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,93E-03 0,02127353 ! proline metabolic process GO:0006560 13 10 0,000 8,93E-03 0,02125249 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,93E-03 0,02123149 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,93E-03 0,02121053 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,93E-03 0,02118961 ! V(D)J recombination GO:0033151 28 10 0,000 8,93E-03 0,02116873 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,93E-03 0,0211479 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,93E-03 0,0211271 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 8,93E-03 0,02110635 ! B cell proliferation GO:0042100 18 10 0,000 8,93E-03 0,02108564 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,93E-03 0,02106496 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,93E-03 0,02104433 ! multicellular organism growth GO:0035264 18 10 0,000 8,93E-03 0,02102374 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,93E-03 0,02100319 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,93E-03 0,02098268 ! epithelial cell development GO:0002064 20 10 0,000 8,93E-03 0,02096221 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,93E-03 0,02094178 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,93E-03 0,02092139 ! macroautophagy GO:0016236 17 10 0,000 8,93E-03 0,02090104 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,93E-03 0,02088072 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,93E-03 0,02086045 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,93E-03 0,02084022 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,93E-03 0,02082002 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,93E-03 0,02079987 ! copper ion homeostasis GO:0055070 13 10 0,000 8,93E-03 0,02077975 ! regulation of bone resorption GO:0045124 25 10 0,000 8,93E-03 0,02075968 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,93E-03 0,02073964 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,93E-03 0,02071964 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,93E-03 0,02069968 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,93E-03 0,02067975 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,93E-03 0,02065987 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,93E-03 0,02064002 ! blastoderm segmentation GO:0007350 18 10 0,000 8,93E-03 0,02062022 ! response to dsRNA GO:0043331 20 10 0,000 8,93E-03 0,02060045 ! DNA ligation GO:0006266 19 10 0,000 8,93E-03 0,02058071 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,93E-03 0,02056102 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,93E-03 0,02054136 ! melanosome localization GO:0032400 16 10 0,000 8,93E-03 0,02052174 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,93E-03 0,02050216 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,93E-03 0,02048262 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,93E-03 0,02046311 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,93E-03 0,02044364 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 8,93E-03 0,02042421 ! mRNA cleavage GO:0006379 17 10 0,000 8,93E-03 0,02040481 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,93E-03 0,02038545 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,93E-03 0,02036613 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,93E-03 0,02034684 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,93E-03 0,02032759 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,93E-03 0,02030838 ! salivary gland development GO:0007431 27 10 0,000 8,93E-03 0,0202892 ! prophase GO:0051324 15 10 0,000 8,93E-03 0,02027006 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,93E-03 0,02025096 ! apical protein localization GO:0045176 15 10 0,000 8,93E-03 0,02023189 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,93E-03 0,02021285 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,93E-03 0,02019386 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,93E-03 0,0201749 ! midbrain development GO:0030901 13 10 0,000 8,93E-03 0,02015597 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,93E-03 0,02013708 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,93E-03 0,02011822 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,93E-03 0,02009941 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,93E-03 0,02008062 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,93E-03 0,02006187 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,93E-03 0,02004316 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 8,93E-03 0,02002448 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,93E-03 0,02000583 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,93E-03 0,01998722 ! oocyte development GO:0048599 17 10 0,000 8,93E-03 0,01996865 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,93E-03 0,01995011 ! blastocyst formation GO:0001825 17 10 0,000 8,93E-03 0,0199316 ! cerebellar cortex development GO:0021695 15 10 0,000 8,93E-03 0,01991313 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 8,93E-03 0,01989469 ! activation of innate immune response GO:0002218 12 10 0,000 8,93E-03 0,01987629 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 8,93E-03 0,01985792 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,93E-03 0,01983958 ! response to nicotine GO:0035094 20 10 0,000 8,93E-03 0,01982128 ! establishment of cell polarity GO:0030010 16 10 0,000 8,93E-03 0,01980301 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,93E-03 0,01978477 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,93E-03 0,01976657 ! localization within membrane GO:0051668 20 10 0,000 8,93E-03 0,0197484 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,819E-03 0,02169394 ! respiratory burst GO:0045730 17 11 0,000 9,819E-03 0,02167404 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,819E-03 0,02165417 ! neuron fate specification GO:0048665 17 11 0,000 9,819E-03 0,02163434 ! telencephalon cell migration GO:0022029 20 11 0,000 9,819E-03 0,02161455 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 9,819E-03 0,02159479 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,819E-03 0,02157507 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,819E-03 0,02155538 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,819E-03 0,02153573 ! Golgi vesicle budding GO:0048194 22 11 0,000 9,819E-03 0,02151612 ! response to pain GO:0048265 24 11 0,000 9,819E-03 0,02149654 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,819E-03 0,021477 ! T cell proliferation GO:0042098 26 11 0,000 9,819E-03 0,02145749 ! blood vessel remodeling GO:0001974 29 11 0,000 9,819E-03 0,02143802 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,819E-03 0,02141859 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 9,819E-03 0,02139918 ! bone resorption GO:0045453 16 11 0,000 9,819E-03 0,02137982 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,819E-03 0,02136049 ! ventral spinal cord development GO:0021517 21 11 0,000 9,819E-03 0,02134119 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,819E-03 0,02132193 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,819E-03 0,0213027 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,819E-03 0,02128351 ! melanocyte differentiation GO:0030318 21 11 0,000 9,819E-03 0,02126436 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,819E-03 0,02124523 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,819E-03 0,02122615 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,819E-03 0,02120709 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,819E-03 0,02118807 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,819E-03 0,02116909 ! lipid digestion GO:0044241 18 11 0,000 9,819E-03 0,02115013 ! substrate-bound cell migration GO:0006929 13 11 0,000 9,819E-03 0,02113122 ! UV protection GO:0009650 19 11 0,000 9,819E-03 0,02111233 ! adult heart development GO:0007512 14 11 0,000 9,819E-03 0,02109348 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,819E-03 0,02107467 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,819E-03 0,02105588 ! temperature homeostasis GO:0001659 17 11 0,000 9,819E-03 0,02103713 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,819E-03 0,02101842 ! negative regulation of ossification GO:0030279 26 11 0,000 9,819E-03 0,02099973 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,819E-03 0,02098108 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,819E-03 0,02096247 ! regulation of organ growth GO:0046620 13 11 0,000 9,819E-03 0,02094388 ! pigment granule localization GO:0051875 20 11 0,000 9,819E-03 0,02092533 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,819E-03 0,02090681 ! vasoconstriction GO:0042310 18 11 0,000 9,819E-03 0,02088833 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,819E-03 0,02086988 ! embryonic axis specification GO:0000578 18 11 0,000 9,819E-03 0,02085146 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,819E-03 0,02083307 ! snRNA metabolic process GO:0016073 24 11 0,000 9,819E-03 0,02081471 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,819E-03 0,02079639 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,819E-03 0,0207781 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,819E-03 0,02075984 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,819E-03 0,02074162 ! zymogen activation GO:0031638 15 11 0,000 9,819E-03 0,02072342 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,819E-03 0,02070526 ! neuroblast proliferation GO:0007405 24 11 0,000 9,819E-03 0,02068713 ! nucleosome positioning GO:0016584 15 11 0,000 9,819E-03 0,02066903 ! regulation of isotype switching GO:0045191 22 11 0,000 9,819E-03 0,02065096 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,819E-03 0,02063293 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,819E-03 0,02061492 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,819E-03 0,02059695 ! acid secretion GO:0046717 18 11 0,000 9,819E-03 0,02057901 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,819E-03 0,0205611 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,819E-03 0,02054322 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,819E-03 0,02052537 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,819E-03 0,02050755 ! oocyte differentiation GO:0009994 18 11 0,000 9,819E-03 0,02048977 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,819E-03 0,02047201 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 9,819E-03 0,02045429 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,819E-03 0,02043659 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,819E-03 0,02041893 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,819E-03 0,02040129 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,819E-03 0,02038369 ! embryonic gut development GO:0048566 15 11 0,000 9,819E-03 0,02036612 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,819E-03 0,02034858 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 9,819E-03 0,02033107 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,819E-03 0,02031359 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,819E-03 0,02029613 ! defense response to fungus GO:0050832 13 11 0,000 9,819E-03 0,02027871 ! prepulse inhibition GO:0060134 18 11 0,000 9,819E-03 0,02026132 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,819E-03 0,02024396 ! sequestering of metal ion GO:0051238 14 11 0,000 9,819E-03 0,02022663 ! lamellipodium assembly GO:0030032 20 11 0,000 9,819E-03 0,02020932 ! regulation of embryonic development GO:0045995 27 11 0,000 9,819E-03 0,02019205 ! nucleus localization GO:0051647 19 11 0,000 9,819E-03 0,02017481 ! regulation of synapse organization GO:0050807 17 11 0,000 9,819E-03 0,02015759 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0107071 0,02196188 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0107071 0,02194318 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0107071 0,0219245 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0107071 0,02190586 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0107071 0,02188725 ! virus-host interaction GO:0019048 29 12 0,000 0,0107071 0,02186867 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0107071 0,02185012 ! cartilage condensation GO:0001502 20 12 0,000 0,0107071 0,0218316 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0107071 0,02181311 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0107071 0,02179466 ! protein complex disassembly GO:0043241 27 12 0,000 0,0107071 0,02177624 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0107071 0,02175784 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0107071 0,02173948 ! hippocampus development GO:0021766 26 12 0,000 0,0107071 0,02172115 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0107071 0,02170285 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0107071 0,02168459 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0107071 0,02166635 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0107071 0,02164814 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0107071 0,02162996 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0107071 0,02161182 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0107071 0,0215937 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0107071 0,02157562 ! drug transport GO:0015893 16 12 0,000 0,0107071 0,02155756 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0107071 0,02153954 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0107071 0,02152154 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0107071 0,02150358 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0107071 0,02148564 ! focal adhesion formation GO:0048041 35 12 0,000 0,0107071 0,02146774 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0107071 0,02144987 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0107071 0,02143202 ! forebrain cell migration GO:0021885 21 12 0,000 0,0107071 0,0214142 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0107071 0,02139642 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0107071 0,02137866 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0107071 0,02136094 ! entry into host cell GO:0030260 32 12 0,000 0,0107071 0,02134324 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0107071 0,02132557 ! monoamine transport GO:0015844 18 12 0,000 0,0107071 0,02130793 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0107071 0,02129032 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0107071 0,02127274 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0107071 0,02125519 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0107071 0,02123767 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0107071 0,02122017 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0107071 0,02120271 ! protein homotetramerization GO:0051289 21 12 0,000 0,0107071 0,02118527 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0107071 0,02116786 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0107071 0,02115048 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0107071 0,02113313 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0107071 0,02111581 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0107071 0,02109852 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0107071 0,02108125 ! cranial nerve development GO:0021545 20 12 0,000 0,0107071 0,02106401 ! fucose catabolic process GO:0019317 22 12 0,000 0,0107071 0,0210468 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0107071 0,02102962 ! histone acetylation GO:0016573 26 12 0,000 0,0107071 0,02101247 ! histone methylation GO:0016571 26 12 0,000 0,0107071 0,02099534 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0107071 0,02097825 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0107071 0,02096118 ! gland morphogenesis GO:0022612 29 12 0,000 0,0107071 0,02094414 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0107071 0,02092712 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0107071 0,02091014 ! T cell homeostasis GO:0043029 25 12 0,000 0,0107071 0,02089318 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0107071 0,02087625 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0107071 0,02085934 ! spleen development GO:0048536 22 12 0,000 0,0107071 0,02084247 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0107071 0,02082562 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0107071 0,02080879 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0107071 0,020792 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0107071 0,02077523 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0107071 0,02075849 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0107071 0,02074178 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0107071 0,02072509 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0107071 0,02070843 ! response to cold GO:0009409 17 12 0,000 0,0107071 0,0206918 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0107071 0,02067519 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0107071 0,02065861 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01159436 0,02235259 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01159436 0,02233469 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01159436 0,02231682 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01159436 0,02229899 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01159436 0,02228118 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01159436 0,02226339 ! lipid localization GO:0010876 28 13 0,000 0,01159436 0,02224564 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,01159436 0,02222791 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01159436 0,02221022 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01159436 0,02219255 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01159436 0,02217491 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01159436 0,02215729 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01159436 0,02213971 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01159436 0,02212215 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01159436 0,02210462 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01159436 0,02208712 ! methionine metabolic process GO:0006555 27 13 0,000 0,01159436 0,02206964 ! plasma membrane organization GO:0007009 24 13 0,000 0,01159436 0,0220522 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01159436 0,02203478 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01159436 0,02201739 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01159436 0,02200002 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01159436 0,02198269 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01159436 0,02196538 ! response to X-ray GO:0010165 25 13 0,000 0,01159436 0,0219481 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01159436 0,02193084 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01159436 0,02191361 ! exocrine system development GO:0035272 32 13 0,000 0,01159436 0,02189641 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01159436 0,02187924 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01159436 0,02186209 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01159436 0,02184497 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01159436 0,02182788 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01159436 0,02181081 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01159436 0,02179377 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01159436 0,02177676 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01159436 0,02175977 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01159436 0,02174281 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01159436 0,02172588 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01159436 0,02170897 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01159436 0,02169209 ! ribosome assembly GO:0042255 17 13 0,000 0,01159436 0,02167524 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01159436 0,02165841 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01159436 0,02164161 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01159436 0,02162483 ! chromatin silencing GO:0006342 26 13 0,000 0,01159436 0,02160808 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01159436 0,02159136 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01159436 0,02157466 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01159436 0,02155798 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01159436 0,02154134 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01159436 0,02152472 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01159436 0,02150812 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01159436 0,02149155 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01159436 0,021475 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01159436 0,02145849 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01159436 0,02144199 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01159436 0,02142552 ! embryonic placenta development GO:0001892 23 13 0,000 0,01159436 0,02140908 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01159436 0,02139266 ! insulin secretion GO:0030073 23 13 0,000 0,01159436 0,02137627 ! actin filament polymerization GO:0030041 24 13 0,000 0,01159436 0,0213599 ! acrosome reaction GO:0007340 18 13 0,000 0,01159436 0,02134356 ! rRNA transcription GO:0009303 25 14 0,000 0,01248085 0,0229579 ! lactation GO:0007595 26 14 0,000 0,01248085 0,02294036 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01248085 0,02292285 ! reproductive cellular process GO:0048610 20 14 0,000 0,01248085 0,02290536 ! tRNA modification GO:0006400 20 14 0,000 0,01248085 0,0228879 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01248085 0,02287047 ! regulation of S phase GO:0033261 23 14 0,000 0,01248085 0,02285307 ! water transport GO:0006833 21 14 0,000 0,01248085 0,02283569 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01248085 0,02281834 ! non-recombinational repair GO:0000726 25 14 0,000 0,01248085 0,02280101 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01248085 0,02278371 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01248085 0,02276644 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01248085 0,02274919 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01248085 0,02273197 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01248085 0,02271477 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01248085 0,0226976 ! palate development GO:0060021 31 14 0,000 0,01248085 0,02268046 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01248085 0,02266334 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01248085 0,02264625 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01248085 0,02262919 ! arginine metabolic process GO:0006525 17 14 0,000 0,01248085 0,02261215 ! regulation of heart rate GO:0002027 24 14 0,000 0,01248085 0,02259513 ! organic alcohol transport GO:0015850 29 14 0,000 0,01248085 0,02257814 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01248085 0,02256118 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01248085 0,02254424 ! embryo implantation GO:0007566 30 14 0,000 0,01248085 0,02252733 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01248085 0,02251044 ! L-amino acid transport GO:0015807 30 14 0,000 0,01248085 0,02249358 ! bone mineralization GO:0030282 17 14 0,000 0,01248085 0,02247674 ! stem cell development GO:0048864 43 14 0,000 0,01248085 0,02245993 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01248085 0,02244315 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01248085 0,02242639 ! cerebellum development GO:0021549 21 14 0,000 0,01248085 0,02240965 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01248085 0,02239294 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01248085 0,02237625 ! response to gamma radiation GO:0010332 28 14 0,000 0,01248085 0,02235959 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01248085 0,02234295 ! cofactor transport GO:0051181 26 14 0,000 0,01248085 0,02232634 ! NADP metabolic process GO:0006739 24 14 0,000 0,01248085 0,02230976 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01248085 0,02229319 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01248085 0,02227665 ! intestinal absorption GO:0050892 25 14 0,000 0,01248085 0,02226014 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01248085 0,02224365 ! oxygen transport GO:0015671 21 14 0,000 0,01248085 0,02222719 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01248085 0,02221075 ! male genitalia development GO:0030539 24 14 0,000 0,01248085 0,02219433 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01248085 0,02217794 ! regulation of axon extension GO:0030516 37 14 0,000 0,01248085 0,02216157 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01248085 0,02214523 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01248085 0,02212891 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01336658 0,02368188 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01336658 0,02366445 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01336658 0,02364705 ! superoxide anion generation GO:0042554 20 15 0,000 0,01336658 0,02362968 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01336658 0,02361233 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01336658 0,023595 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01336658 0,0235777 ! copper ion transport GO:0006825 20 15 0,000 0,01336658 0,02356043 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01336658 0,02354318 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01336658 0,02352596 ! sulfate transport GO:0008272 23 15 0,000 0,01336658 0,02350876 ! response to cAMP GO:0051591 22 15 0,000 0,01336658 0,02349159 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01336658 0,02347444 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01336658 0,02345732 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01336658 0,02344022 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01336658 0,02342315 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01336658 0,0234061 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01336658 0,02338908 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01336658 0,02337208 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01336658 0,02335511 ! pituitary gland development GO:0021983 29 15 0,000 0,01336658 0,02333816 ! vesicle coating GO:0006901 33 15 0,000 0,01336658 0,02332124 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01336658 0,02330434 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01336658 0,02328746 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01336658 0,02327061 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01336658 0,02325379 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01336658 0,02323699 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01336658 0,02322021 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01336658 0,02320345 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01336658 0,02318673 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01336658 0,02317002 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01336658 0,02315334 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01336658 0,02313668 ! tissue regeneration GO:0042246 26 15 0,000 0,01336658 0,02312005 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01336658 0,02310344 ! water homeostasis GO:0030104 27 15 0,000 0,01336658 0,02308685 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01336658 0,02307029 ! muscle maintenance GO:0046716 26 15 0,000 0,01336658 0,02305375 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01336658 0,02303724 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01336658 0,02302075 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01336658 0,02300428 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01336658 0,02298784 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01336658 0,02297142 ! cell killing GO:0001906 29 15 0,000 0,01336658 0,02295502 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01336658 0,02293865 ! detection of bacterium GO:0016045 18 15 0,000 0,01336658 0,0229223 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01336658 0,02290597 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01336658 0,02288967 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01336658 0,02287339 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01336658 0,02285713 ! peptide hormone processing GO:0016486 23 15 0,000 0,01336658 0,0228409 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01425154 0,02433584 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01425154 0,02431858 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01425154 0,02430135 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01425154 0,02428414 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01425154 0,02426695 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01425154 0,02424979 ! bone remodeling GO:0046849 27 16 0,000 0,01425154 0,02423265 ! filopodium assembly GO:0046847 32 16 0,000 0,01425154 0,02421554 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01425154 0,02419845 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01425154 0,02418139 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01425154 0,02416434 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01425154 0,02414733 ! startle response GO:0001964 28 16 0,000 0,01425154 0,02413033 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01425154 0,02411336 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01425154 0,02409642 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01425154 0,0240795 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01425154 0,0240626 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01425154 0,02404573 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01425154 0,02402888 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01425154 0,02401205 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01425154 0,02399524 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01425154 0,02397846 ! response to osmotic stress GO:0006970 25 16 0,000 0,01425154 0,02396171 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01425154 0,02394498 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01425154 0,02392827 ! fructose metabolic process GO:0006000 25 16 0,000 0,01425154 0,02391158 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01425154 0,02389492 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01425154 0,02387828 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01425154 0,02386166 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01425154 0,02384507 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01425154 0,0238285 ! axon cargo transport GO:0008088 43 16 0,000 0,01425154 0,02381195 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01425154 0,02379542 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01425154 0,02377892 ! DNA replication initiation GO:0006270 27 16 0,000 0,01425154 0,02376244 ! neuron recognition GO:0008038 35 16 0,000 0,01425154 0,02374599 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01425154 0,02372955 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01425154 0,02371314 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01425154 0,02369676 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01425154 0,02368039 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01425154 0,02366405 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01425154 0,02364773 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01425154 0,02363143 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01425154 0,02361515 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01425154 0,0235989 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01425154 0,02358267 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01425154 0,02356646 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01425154 0,02355028 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01425154 0,02353411 ! defense response to virus GO:0051607 37 16 0,000 0,01425154 0,02351797 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01513574 0,02495996 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01513574 0,02494286 ! metencephalon development GO:0022037 30 17 0,000 0,01513574 0,02492579 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01513574 0,02490874 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01513574 0,02489172 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01513574 0,02487471 ! signal complex assembly GO:0007172 41 17 0,000 0,01513574 0,02485774 ! endothelial cell migration GO:0043542 28 17 0,000 0,01513574 0,02484078 ! inositol metabolic process GO:0006020 28 17 0,000 0,01513574 0,02482385 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01513574 0,02480694 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01513574 0,02479005 ! glial cell development GO:0021782 27 17 0,000 0,01513574 0,02477319 ! limbic system development GO:0021761 36 17 0,000 0,01513574 0,02475634 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01513574 0,02473953 ! adult walking behavior GO:0007628 33 17 0,000 0,01513574 0,02472273 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01513574 0,02470596 ! heart looping GO:0001947 30 17 0,000 0,01513574 0,02468921 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01513574 0,02467248 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01513574 0,02465578 ! myoblast differentiation GO:0045445 45 17 0,000 0,01513574 0,02463909 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01513574 0,02462244 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01513574 0,0246058 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01513574 0,02458918 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01513574 0,02457259 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01513574 0,02455602 ! glycine metabolic process GO:0006544 28 17 0,000 0,01513574 0,02453948 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01513574 0,02452295 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01513574 0,02450645 ! NAD metabolic process GO:0019674 29 17 0,000 0,01513574 0,02448997 ! membrane budding GO:0006900 37 17 0,000 0,01513574 0,02447351 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01513574 0,02445707 ! regulation of protein binding GO:0043393 33 17 0,000 0,01513574 0,02444066 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01513574 0,02442427 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01513574 0,0244079 ! genitalia development GO:0048806 30 17 0,000 0,01513574 0,02439155 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01513574 0,02437522 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01513574 0,02435892 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01513574 0,02434264 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01513574 0,02432637 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01513574 0,02431014 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01513574 0,02429392 ! steroid catabolic process GO:0006706 31 17 0,000 0,01513574 0,02427772 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01513574 0,02426155 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01513574 0,02424539 ! gas transport GO:0015669 25 17 0,000 0,01513574 0,02422926 ! organic cation transport GO:0015695 31 17 0,000 0,01513574 0,02421315 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01513574 0,02419706 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01513574 0,024181 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01513574 0,02416495 ! microspike assembly GO:0030035 36 17 0,000 0,01513574 0,02414893 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01513574 0,02413292 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01513574 0,02411694 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01601917 0,02550769 ! neuron maturation GO:0042551 42 18 0,000 0,01601917 0,02549082 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01601917 0,02547397 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01601917 0,02545715 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01601917 0,02544034 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01601917 0,02542356 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01601917 0,0254068 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01601917 0,02539007 ! memory GO:0007613 31 18 0,000 0,01601917 0,02537335 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01601917 0,02535666 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01601917 0,02533999 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01601917 0,02532334 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01601917 0,02530671 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01601917 0,02529011 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01601917 0,02527352 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01601917 0,02525696 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01601917 0,02524042 ! response to retinoic acid GO:0032526 26 18 0,000 0,01601917 0,0252239 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01601917 0,02520741 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01601917 0,02519093 ! response to fungus GO:0009620 21 18 0,000 0,01601917 0,02517448 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01601917 0,02515804 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01601917 0,02514163 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01601917 0,02512524 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01601917 0,02510887 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01601917 0,02509253 ! vitamin transport GO:0051180 27 18 0,000 0,01601917 0,0250762 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01601917 0,0250599 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01601917 0,02504361 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01601917 0,02502735 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01601917 0,02501111 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01601917 0,02499489 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01601917 0,02497869 ! nerve development GO:0021675 28 18 0,000 0,01601917 0,02496251 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01601917 0,02494636 ! protein secretion GO:0009306 39 19 0,000 0,01690184 0,0263039 ! positive regulation of translation GO:0045727 30 19 0,000 0,01690184 0,02628689 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01690184 0,02626991 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01690184 0,02625295 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01690184 0,02623602 ! skin development GO:0043588 36 19 0,000 0,01690184 0,0262191 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01690184 0,02620221 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01690184 0,02618534 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01690184 0,02616849 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01690184 0,02615166 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01690184 0,02613485 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01690184 0,02611806 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01690184 0,0261013 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01690184 0,02608456 ! cerebral cortex development GO:0021987 36 19 0,000 0,01690184 0,02606784 ! pigmentation during development GO:0048066 41 19 0,000 0,01690184 0,02605114 ! response to vitamin A GO:0033189 27 19 0,000 0,01690184 0,02603446 ! heme metabolic process GO:0042168 36 19 0,000 0,01690184 0,0260178 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01690184 0,02600117 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01690184 0,02598455 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01690184 0,02596796 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01690184 0,02595139 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01690184 0,02593484 ! peptide cross-linking GO:0018149 37 19 0,000 0,01690184 0,02591831 ! protein export from nucleus GO:0006611 36 19 0,000 0,01690184 0,0259018 ! heart process GO:0003015 30 19 0,000 0,01690184 0,02588531 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01690184 0,02586885 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01690184 0,0258524 ! visual learning GO:0008542 36 19 0,000 0,01690184 0,02583598 ! cellular pigmentation GO:0033059 36 19 0,000 0,01690184 0,02581957 ! G1 phase GO:0051318 40 19 0,000 0,01690184 0,02580319 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01690184 0,02578683 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01690184 0,02577049 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01690184 0,02575416 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01690184 0,02573786 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01690184 0,02572159 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01690184 0,02570533 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01690184 0,02568909 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01690184 0,02567287 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01690184 0,02565667 ! cilium assembly GO:0042384 37 19 0,000 0,01690184 0,0256405 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01690184 0,02562434 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01778375 0,02694439 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01778375 0,02692744 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01778375 0,0269105 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01778375 0,02689359 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01778375 0,02687669 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01778375 0,02685982 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01778375 0,02684297 ! response to vitamin GO:0033273 31 20 0,000 0,01778375 0,02682614 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01778375 0,02680933 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01778375 0,02679255 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01778375 0,02677578 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01778375 0,02675903 ! response to alkaloid GO:0043279 38 20 0,000 0,01778375 0,02674231 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01778375 0,02672561 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01778375 0,02670892 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01778375 0,02669226 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01778375 0,02667562 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01778375 0,026659 ! cellular response to starvation GO:0009267 33 20 0,000 0,01778375 0,0266424 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01778375 0,02662582 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01778375 0,02660926 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01778375 0,02659273 ! body fluid secretion GO:0007589 31 20 0,000 0,01778375 0,02657621 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01778375 0,02655971 ! peptide secretion GO:0002790 35 20 0,000 0,01778375 0,02654324 ! stem cell differentiation GO:0048863 53 20 0,000 0,01778375 0,02652678 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01778375 0,02651034 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01778375 0,02649393 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01778375 0,02647753 ! sensory perception of pain GO:0019233 30 20 0,000 0,01778375 0,02646116 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01778375 0,02644481 ! diencephalon development GO:0021536 34 20 0,000 0,01778375 0,02642847 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01778375 0,02641216 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01778375 0,02639586 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01778375 0,02637959 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01778375 0,02636334 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01778375 0,0263471 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01778375 0,02633089 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01778375 0,0263147 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01778375 0,02629852 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01778375 0,02628237 ! regulation of glucose import GO:0046324 29 20 0,000 0,01778375 0,02626623 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01778375 0,02625012 ! actin filament-based movement GO:0030048 43 20 0,000 0,01778375 0,02623403 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01778375 0,02621795 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01778375 0,0262019 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01778375 0,02618586 ! negative regulation of translation GO:0017148 29 20 0,000 0,01778375 0,02616984 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01778375 0,02615385 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01778375 0,02613787 ! regulation of cell killing GO:0031341 42 21 0,000 0,01866489 0,0274162 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01866489 0,02739947 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01866489 0,02738276 ! hormone secretion GO:0046879 38 21 0,000 0,01866489 0,02736608 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01866489 0,02734941 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01866489 0,02733276 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01866489 0,02731614 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01866489 0,02729953 ! ovarian follicle development GO:0001541 35 21 0,000 0,01866489 0,02728295 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01866489 0,02726638 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01866489 0,02724984 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01866489 0,02723331 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01866489 0,02721681 ! cell aging GO:0007569 44 21 0,000 0,01866489 0,02720032 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01866489 0,02718386 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01866489 0,02716741 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01866489 0,02715099 ! cytolysis GO:0019835 24 21 0,000 0,01866489 0,02713458 ! vasodilation GO:0042311 39 21 0,000 0,01866489 0,0271182 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01866489 0,02710183 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01866489 0,02708548 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01866489 0,02706916 ! oogenesis GO:0048477 36 21 0,000 0,01866489 0,02705285 ! DNA modification GO:0006304 34 21 0,000 0,01866489 0,02703656 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01866489 0,0270203 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01866489 0,02700405 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01866489 0,02698782 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01866489 0,02697161 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01866489 0,02695542 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01866489 0,02693925 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01866489 0,0269231 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01866489 0,02690697 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01866489 0,02689086 ! collagen catabolic process GO:0030574 28 21 0,000 0,01866489 0,02687476 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01866489 0,02685869 ! gut development GO:0048565 39 21 0,000 0,01866489 0,02684264 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01954528 0,02809196 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01954528 0,02807519 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01954528 0,02805843 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01954528 0,0280417 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01954528 0,02802499 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01954528 0,0280083 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01954528 0,02799163 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01954528 0,02797498 ! regeneration GO:0031099 41 22 0,000 0,01954528 0,02795835 ! keratinization GO:0031424 28 22 0,000 0,01954528 0,02794173 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01954528 0,02792514 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01954528 0,02790857 ! sensory perception of taste GO:0050909 28 22 0,000 0,01954528 0,02789201 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01954528 0,02787548 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01954528 0,02785897 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01954528 0,02784247 ! vacuolar transport GO:0007034 36 22 0,000 0,01954528 0,027826 ! lysosome organization GO:0007040 41 22 0,000 0,01954528 0,02780954 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01954528 0,02779311 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01954528 0,02777669 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01954528 0,02776029 ! fucose metabolic process GO:0006004 39 22 0,000 0,01954528 0,02774392 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01954528 0,02772756 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01954528 0,02771122 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01954528 0,0276949 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01954528 0,0276786 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01954528 0,02766232 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01954528 0,02764605 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01954528 0,02762981 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01954528 0,02761359 ! sarcomere organization GO:0045214 30 22 0,000 0,01954528 0,02759738 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01954528 0,02758119 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01954528 0,02756503 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01954528 0,02754888 ! protein stabilization GO:0050821 39 22 0,000 0,01954528 0,02753275 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0204249 0,02875501 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0204249 0,02873819 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0204249 0,0287214 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0204249 0,02870462 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0204249 0,02868786 ! gluconeogenesis GO:0006094 33 23 0,000 0,0204249 0,02867113 ! viral genome replication GO:0019079 41 23 0,000 0,0204249 0,02865441 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0204249 0,02863771 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0204249 0,02862103 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0204249 0,02860437 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0204249 0,02858773 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0204249 0,02857111 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0204249 0,02855451 ! visual behavior GO:0007632 42 23 0,000 0,0204249 0,02853793 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0204249 0,02852136 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0204249 0,02850482 ! response to ethanol GO:0045471 46 23 0,000 0,0204249 0,0284883 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0204249 0,02847179 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0204249 0,0284553 ! peroxisome organization GO:0007031 37 23 0,000 0,0204249 0,02843884 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0204249 0,02842239 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0204249 0,02840596 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0204249 0,02838955 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0204249 0,02837316 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0204249 0,02835679 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0204249 0,02834043 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0204249 0,0283241 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0204249 0,02830778 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0204249 0,02829149 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0204249 0,02827521 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0204249 0,02825895 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0204249 0,02824271 ! fatty acid transport GO:0015908 44 23 0,000 0,0204249 0,02822649 ! platelet activation GO:0030168 37 23 0,000 0,0204249 0,02821028 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0204249 0,0281941 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0204249 0,02817793 ! hormone transport GO:0009914 40 23 0,000 0,0204249 0,02816178 ! cell-cell recognition GO:0009988 25 23 0,000 0,0204249 0,02814565 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0204249 0,02812954 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0204249 0,02811345 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0204249 0,02809738 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0204249 0,02808132 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0204249 0,02806528 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02130376 0,0292562 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02130376 0,02923951 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02130376 0,02922284 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02130376 0,02920619 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02130376 0,02918955 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02130376 0,02917294 ! vesicle docking GO:0048278 47 24 0,000 0,02130376 0,02915635 ! spinal cord development GO:0021510 47 24 0,000 0,02130376 0,02913977 ! vacuole organization GO:0007033 43 24 0,000 0,02130376 0,02912321 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02130376 0,02910668 ! digestive system process GO:0022600 39 24 0,000 0,02130376 0,02909016 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02130376 0,02907366 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02130376 0,02905718 ! regulation of behavior GO:0050795 43 24 0,000 0,02130376 0,02904071 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02130376 0,02902427 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02130376 0,02900784 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02130376 0,02899144 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02130376 0,02897505 ! membrane depolarization GO:0051899 39 24 0,000 0,02130376 0,02895868 ! pallium development GO:0021543 49 24 0,000 0,02130376 0,02894233 ! pentose metabolic process GO:0019321 35 24 0,000 0,02130376 0,02892599 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02130376 0,02890968 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02130376 0,02889338 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02130376 0,0288771 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02130376 0,02886084 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02130376 0,0288446 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02130376 0,02882838 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02130376 0,02881217 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02130376 0,02879599 ! regulation of amine transport GO:0051952 40 24 0,000 0,02130376 0,02877982 ! protein tetramerization GO:0051262 52 24 0,000 0,02130376 0,02876367 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02218187 0,02993246 ! myelination GO:0042552 45 25 0,000 0,02218187 0,02991568 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02218187 0,02989892 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02218187 0,02988218 ! phototransduction GO:0007602 33 25 0,000 0,02218187 0,02986546 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02218187 0,02984876 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02218187 0,02983207 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02218187 0,02981541 ! sperm motility GO:0030317 31 25 0,000 0,02218187 0,02979876 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02218187 0,02978213 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02218187 0,02976552 ! receptor metabolic process GO:0043112 46 25 0,000 0,02218187 0,02974893 ! chromosome condensation GO:0030261 45 25 0,000 0,02218187 0,02973235 ! response to starvation GO:0042594 42 25 0,000 0,02218187 0,0297158 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02218187 0,02969926 ! neural crest cell development GO:0014032 54 25 0,000 0,02218187 0,02968275 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02218187 0,02966625 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02218187 0,02964977 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02218187 0,0296333 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02218187 0,02961686 ! interaction with host GO:0051701 62 25 0,000 0,02218187 0,02960043 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02218187 0,02958402 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02218187 0,02956763 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02218187 0,02955126 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02218187 0,02953491 ! immunoglobulin production GO:0002377 55 25 0,000 0,02218187 0,02951857 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02218187 0,02950225 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02218187 0,02948595 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02218187 0,02946967 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02218187 0,02945341 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02218187 0,02943716 ! telomere organization GO:0032200 43 25 0,000 0,02218187 0,02942094 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02218187 0,02940473 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02218187 0,02938853 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02305921 0,03053411 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02305921 0,03051731 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02305921 0,03050053 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02305921 0,03048378 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02305921 0,03046704 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02305921 0,03045031 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02305921 0,03043361 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02305921 0,03041692 ! molting cycle process GO:0022404 50 26 0,000 0,02305921 0,03040026 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02305921 0,03038361 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02305921 0,03036698 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02305921 0,03035037 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02305921 0,03033377 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02305921 0,0303172 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02305921 0,03030064 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02305921 0,0302841 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02305921 0,03026758 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02305921 0,03025107 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02305921 0,03023459 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02305921 0,03021812 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02305921 0,03020167 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02305921 0,03018524 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02305921 0,03016883 ! blastocyst development GO:0001824 49 26 0,000 0,02305921 0,03015243 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02305921 0,03013605 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02305921 0,03011969 ! neuron fate commitment GO:0048663 48 27 0,000 0,0239358 0,03124772 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0239358 0,03123077 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0239358 0,03121384 ! iron ion transport GO:0006826 59 27 0,000 0,0239358 0,03119693 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0239358 0,03118004 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0239358 0,03116317 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0239358 0,03114632 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0239358 0,03112948 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0239358 0,03111266 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0239358 0,03109586 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0239358 0,03107908 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0239358 0,03106232 ! autophagy GO:0006914 41 27 0,000 0,0239358 0,03104557 ! male gonad development GO:0008584 44 27 0,000 0,0239358 0,03102885 ! response to toxin GO:0009636 47 27 0,000 0,0239358 0,03101214 ! primary neural tube formation GO:0014020 51 27 0,000 0,0239358 0,03099545 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0239358 0,03097877 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0239358 0,03096212 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0239358 0,03094548 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0239358 0,03092886 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0239358 0,03091226 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0239358 0,03089568 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0239358 0,03087911 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02481163 0,03199185 ! circadian rhythm GO:0007623 50 28 0,000 0,02481163 0,03197471 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02481163 0,0319576 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02481163 0,0319405 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02481163 0,03192342 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02481163 0,03190635 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02481163 0,03188931 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02481163 0,03187228 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02481163 0,03185528 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02481163 0,03183829 ! synaptogenesis GO:0007416 42 28 0,000 0,02481163 0,03182132 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02481163 0,03180436 ! lipid oxidation GO:0034440 43 28 0,000 0,02481163 0,03178743 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02481163 0,03177051 ! translational initiation GO:0006413 65 29 0,000 0,02568671 0,03287352 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02568671 0,03285604 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02568671 0,03283858 ! regulation of pH GO:0006885 43 29 0,000 0,02568671 0,03282114 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02568671 0,03280372 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02568671 0,03278632 ! catechol metabolic process GO:0009712 54 29 0,000 0,02568671 0,03276894 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02568671 0,03275157 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02568671 0,03273422 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02568671 0,0327169 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02568671 0,03269958 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02568671 0,03268229 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02568671 0,03266502 ! cell fate determination GO:0001709 60 29 0,000 0,02568671 0,03264776 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02568671 0,03263053 ! detection of light stimulus GO:0009583 38 29 0,000 0,02568671 0,03261331 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02568671 0,03259611 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02568671 0,03257892 ! regulation of coagulation GO:0050818 46 29 0,000 0,02568671 0,03256176 ! phenol metabolic process GO:0018958 55 30 0,000 0,02656102 0,03365236 ! zinc ion transport GO:0006829 45 30 0,000 0,02656102 0,03363464 ! membrane docking GO:0022406 61 30 0,000 0,02656102 0,03361695 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02656102 0,03359928 ! cell junction assembly GO:0034329 78 30 0,000 0,02656102 0,03358162 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02656102 0,03356398 ! acute-phase response GO:0006953 49 30 0,000 0,02656102 0,03354636 ! myofibril assembly GO:0030239 47 30 0,000 0,02656102 0,03352876 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02656102 0,03351118 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02656102 0,03349362 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02656102 0,03347607 ! phospholipid transport GO:0015914 51 30 0,000 0,02656102 0,03345855 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02656102 0,03344104 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02656102 0,03342355 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02656102 0,03340608 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02656102 0,03338862 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02656102 0,03337119 ! eye morphogenesis GO:0048592 60 30 0,000 0,02656102 0,03335377 ! response to heat GO:0009408 50 30 0,000 0,02656102 0,03333637 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02743459 0,03441481 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02743459 0,03439688 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02743459 0,03437896 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02743459 0,03436107 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02743459 0,03434319 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02743459 0,03432533 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02743459 0,03430749 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02743459 0,03428967 ! ovulation cycle process GO:0022602 49 31 0,000 0,02743459 0,03427187 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02743459 0,03425408 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02743459 0,03423631 ! peptide transport GO:0015833 55 31 0,000 0,02743459 0,03421857 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02743459 0,03420084 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02743459 0,03418312 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02743459 0,03416543 ! mesoderm formation GO:0001707 69 31 0,000 0,02743459 0,03414776 ! natural killer cell activation GO:0030101 45 31 0,000 0,02743459 0,0341301 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02743459 0,03411246 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02743459 0,03409484 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02743459 0,03407724 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02743459 0,03405966 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02743459 0,03404209 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02830739 0,035107 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02830739 0,03508892 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02830739 0,03507085 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02830739 0,0350528 ! cholesterol transport GO:0030301 56 32 0,000 0,02830739 0,03503477 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02830739 0,03501675 ! spliceosome assembly GO:0000245 67 32 0,000 0,02830739 0,03499876 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02830739 0,03498078 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02830739 0,03496283 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02830739 0,03494489 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02830739 0,03492697 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02830739 0,03490906 ! muscle cell development GO:0055001 49 32 0,000 0,02830739 0,03489118 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02830739 0,03487332 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02830739 0,03485547 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02830739 0,03483764 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02830739 0,03481983 ! ovulation cycle GO:0042698 51 32 0,000 0,02830739 0,03480204 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02830739 0,03478426 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02830739 0,03476651 ! hindbrain development GO:0030902 61 32 0,000 0,02830739 0,03474877 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02830739 0,03473105 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02830739 0,03471335 ! gene silencing GO:0016458 65 32 0,000 0,02830739 0,03469566 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02917944 0,03574631 ! post-embryonic development GO:0009791 69 33 0,000 0,02917944 0,03572811 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02917944 0,03570994 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02917944 0,03569179 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02917944 0,03567365 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02917944 0,03565553 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02917944 0,03563743 ! sterol transport GO:0015918 57 33 0,000 0,02917944 0,03561935 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02917944 0,03560129 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02917944 0,03558325 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02917944 0,03556522 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02917944 0,03554721 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03005074 0,03659013 ! glial cell differentiation GO:0010001 63 34 0,000 0,03005074 0,03657162 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03005074 0,03655313 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03005074 0,03653466 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03005074 0,03651621 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03005074 0,03649777 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03005074 0,03647936 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03005074 0,03646096 ! mismatch repair GO:0006298 46 34 0,000 0,03005074 0,03644259 ! spermatid development GO:0007286 63 34 0,000 0,03005074 0,03642423 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03005074 0,03640589 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03005074 0,03638756 ! placenta development GO:0001890 53 34 0,000 0,03005074 0,03636926 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03005074 0,03635097 ! regulation of muscle development GO:0048634 70 35 0,000 0,03092129 0,03738524 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03092129 0,03736646 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03092129 0,0373477 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03092129 0,03732896 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03092129 0,03731024 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03092129 0,03729154 ! odontogenesis GO:0042476 66 35 0,000 0,03092129 0,03727286 ! female gonad development GO:0008585 58 35 0,000 0,03092129 0,03725419 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03092129 0,03723555 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03092129 0,03721692 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,03092129 0,03719831 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03092129 0,03717972 ! cytokine production GO:0001816 59 35 0,000 0,03092129 0,03716115 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,03092129 0,0371426 ! neural tube formation GO:0001841 67 35 0,000 0,03092129 0,03712406 ! vesicle localization GO:0051648 64 35 0,000 0,03092129 0,03710555 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03179108 0,03813028 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03179108 0,03811128 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03179108 0,0380923 ! cell junction organization GO:0034330 86 36 0,000 0,03179108 0,03807334 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03179108 0,0380544 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03179108 0,03803548 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03179108 0,03801657 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03179108 0,03799769 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03179108 0,03797882 ! aerobic respiration GO:0009060 55 36 0,000 0,03179108 0,03795997 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03179108 0,03794114 ! embryonic organ development GO:0048568 57 36 0,000 0,03179108 0,03792233 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03179108 0,03790354 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03179108 0,03788477 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03266012 0,03890112 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03266012 0,03888187 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03266012 0,03886264 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03266012 0,03884343 ! organic anion transport GO:0015711 68 37 0,000 0,03266012 0,03882424 ! tissue remodeling GO:0048771 76 37 0,000 0,03266012 0,03880507 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03266012 0,03878591 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03266012 0,03876678 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03266012 0,03874766 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03266012 0,03872857 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03266012 0,03870949 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03266012 0,03869043 ! pigment metabolic process GO:0042440 80 37 0,000 0,03266012 0,03867139 ! spermatid differentiation GO:0048515 66 37 0,000 0,03266012 0,03865237 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03266012 0,03863336 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03352841 0,03964097 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03352841 0,0396215 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03352841 0,03960205 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03352841 0,03958261 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03352841 0,0395632 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03352841 0,03954381 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03352841 0,03952443 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03352841 0,03950508 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03352841 0,03948574 ! lipid homeostasis GO:0055088 67 38 0,000 0,03352841 0,03946642 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03352841 0,03944712 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03352841 0,03942784 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03352841 0,03940858 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03352841 0,03938934 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03352841 0,03937012 ! glucan metabolic process GO:0044042 62 38 0,000 0,03352841 0,03935091 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03439595 0,04034942 ! mammary gland development GO:0030879 86 39 0,000 0,03439595 0,04032976 ! learning GO:0007612 77 39 0,000 0,03439595 0,04031012 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03439595 0,04029049 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03439595 0,04027088 ! segmentation GO:0035282 67 39 0,000 0,03439595 0,0402513 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03439595 0,04023173 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03439595 0,04021218 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03439595 0,04019265 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03439595 0,04017314 ! RNA modification GO:0009451 57 39 0,000 0,03439595 0,04015365 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03439595 0,04013417 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03526274 0,04112562 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03526274 0,0411057 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03526274 0,04108579 ! feeding behavior GO:0007631 59 40 0,000 0,03526274 0,04106591 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03526274 0,04104604 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03526274 0,04102619 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03526274 0,04100636 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03612879 0,04199317 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03612879 0,04197289 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03612879 0,04195263 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03612879 0,0419324 ! gliogenesis GO:0042063 88 41 0,000 0,03612879 0,04191218 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03612879 0,04189198 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03612879 0,0418718 ! T cell differentiation GO:0030217 81 41 0,000 0,03612879 0,04185164 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,03612879 0,0418315 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03612879 0,04181138 ! female gamete generation GO:0007292 61 41 0,000 0,03612879 0,04179128 ! polyol metabolic process GO:0019751 66 41 0,000 0,03612879 0,0417712 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03699408 0,04275108 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03699408 0,04273056 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03699408 0,04271005 ! regulation of tube size GO:0035150 71 42 0,000 0,03699408 0,04268957 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03699408 0,0426691 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03699408 0,04264866 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03699408 0,04262823 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03699408 0,04260783 ! neuron migration GO:0001764 79 42 0,000 0,03699408 0,04258744 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03699408 0,04256707 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03699408 0,04254673 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03785862 0,04352023 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03785862 0,04349945 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03785862 0,04347868 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03785862 0,04345794 ! glucose transport GO:0015758 65 43 0,000 0,03785862 0,04343722 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03785862 0,04341651 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03785862 0,04339583 ! neural tube development GO:0021915 77 43 0,000 0,03785862 0,04337516 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03785862 0,04335452 ! striated muscle contraction GO:0006941 77 43 0,000 0,03785862 0,04333389 ! phagocytosis GO:0006909 90 43 0,000 0,03785862 0,04331329 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03785862 0,0432927 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03872242 0,04425945 ! hexose transport GO:0008645 67 44 0,000 0,03872242 0,04423843 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03872242 0,04421744 ! male sex differentiation GO:0046661 76 44 0,000 0,03872242 0,04419646 ! double-strand break repair GO:0006302 81 44 0,000 0,03872242 0,0441755 ! biopolymer methylation GO:0043414 84 44 0,000 0,03872242 0,04415457 ! B cell differentiation GO:0030183 107 44 0,000 0,03872242 0,04413365 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03872242 0,04411275 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03872242 0,04409188 ! developmental growth GO:0048589 82 44 0,000 0,03872242 0,04407102 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03958547 0,04503198 ! glycolysis GO:0006096 65 45 0,000 0,03958547 0,0450107 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03958547 0,04498944 ! leukocyte migration GO:0050900 68 45 0,000 0,03958547 0,04496819 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03958547 0,04494697 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03958547 0,04492577 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03958547 0,04490459 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03958547 0,04488343 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03958547 0,04486229 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03958547 0,04484117 ! cell growth GO:0016049 84 45 0,000 0,03958547 0,04482006 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,04044777 0,04577485 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,04044777 0,04575333 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,04044777 0,04573183 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,04044777 0,04571035 ! pigmentation GO:0043473 100 46 0,000 0,04044777 0,04568889 ! response to insulin stimulus GO:0032868 95 46 0,000 0,04044777 0,04566745 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,04044777 0,04564603 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04130933 0,04659646 ! endosome transport GO:0016197 108 47 0,000 0,04130933 0,04657462 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04130933 0,04655281 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04130933 0,04653101 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04130933 0,04650924 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04130933 0,04648749 ! methylation GO:0032259 90 47 0,000 0,04130933 0,04646575 ! protein homooligomerization GO:0051260 76 47 0,000 0,04130933 0,04644404 ! mitochondrial transport GO:0006839 82 48 0,000 0,04217014 0,04738971 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04217014 0,04736758 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04217014 0,04734548 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04217014 0,0473234 ! activation of caspase activity GO:0006919 84 48 0,000 0,04217014 0,04730133 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04217014 0,04727929 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04217014 0,04725727 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04217014 0,04723527 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04303021 0,04817622 ! regulation of action potential GO:0001508 95 49 0,000 0,04303021 0,04815381 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04303021 0,04813142 ! regulation of ion transport GO:0043269 77 49 0,000 0,04303021 0,04810906 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04303021 0,04808671 ! peptide metabolic process GO:0006518 76 49 0,000 0,04303021 0,04806439 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04303021 0,04804208 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04303021 0,0480198 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04303021 0,04799754 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04303021 0,0479753 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04303021 0,04795307 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04388954 0,04888807 ! neuromuscular process GO:0050905 99 50 0,000 0,04388954 0,04886544 ! regulation of ossification GO:0030278 117 50 0,000 0,04388954 0,04884284 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04388954 0,04882026 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04388954 0,0487977 ! positive regulation of binding GO:0051099 78 51 0,000 0,04474812 0,04972932 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04474812 0,04970636 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04474812 0,04968342 ! excretion GO:0007588 83 51 0,000 0,04474812 0,0496605 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04474812 0,04963761 ! chromatin remodeling GO:0006338 109 51 0,000 0,04474812 0,04961473 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04474812 0,04959188 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04474812 0,04956905 ! vesicle organization GO:0016050 107 51 0,000 0,04474812 0,04954624 ! regulation of cell shape GO:0008360 125 51 0,000 0,04474812 0,04952345 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04560596 0,05044962 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04560596 0,05042644 ! membrane fusion GO:0006944 110 52 0,000 0,04560596 0,05040328 ! positive regulation of growth GO:0045927 90 52 0,000 0,04560596 0,05038013 ! amino acid activation GO:0043038 92 52 0,000 0,04560596 0,05035701 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04560596 0,05033391 ! synapse organization GO:0050808 85 52 0,000 0,04560596 0,05031084 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04646306 0,05123286 ! RNA catabolic process GO:0006401 93 53 0,000 0,04646306 0,0512094 ! regulation of translational initiation GO:0006446 82 53 0,000 0,04646306 0,05118595 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04646306 0,05116252 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04646306 0,05113912 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04646306 0,05111573 ! cell maturation GO:0048469 100 53 0,000 0,04646306 0,05109237 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,04646306 0,05106903 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04646306 0,05104571 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04731941 0,0519628 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04731941 0,0519391 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04731941 0,05191541 ! cell recognition GO:0008037 85 54 0,000 0,04731941 0,05189175 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04731941 0,05186811 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04731941 0,05184449 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04731941 0,05182089 ! chloride transport GO:0006821 90 55 0,000 0,04817503 0,0527339 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04817503 0,05270992 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04817503 0,05268596 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04817503 0,05266202 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04817503 0,05263811 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04817503 0,05261421 ! aging GO:0007568 103 55 0,000 0,04817503 0,05259034 ! gastrulation GO:0007369 112 55 0,000 0,04817503 0,05256649 ! heart morphogenesis GO:0003007 97 55 0,000 0,04817503 0,05254266 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04817503 0,05251886 ! RNA elongation GO:0006354 79 55 0,000 0,04817503 0,05249507 ! nuclear export GO:0051168 97 55 0,000 0,04817503 0,05247131 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04817503 0,05244756 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0490299 0,05335411 ! sensory perception of smell GO:0007608 80 56 0,000 0,0490299 0,05332999 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0490299 0,0533059 ! proton transport GO:0015992 94 56 0,000 0,0490299 0,05328182 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04988404 0,05418555 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04988404 0,0541611 ! lipid modification GO:0030258 97 57 0,000 0,04988404 0,05413667 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04988404 0,05411226 ! hydrogen transport GO:0006818 97 58 0,000 0,05073744 0,05501319 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05073744 0,05498841 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05073744 0,05496365 ! adult behavior GO:0030534 99 58 0,000 0,05073744 0,05493892 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05073744 0,0549142 ! positive regulation of secretion GO:0051047 95 59 0,000 0,0515901 0,05581195 ! regulation of cellular component size GO:0032535 109 59 0,000 0,0515901 0,05578686 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,0515901 0,0557618 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,0515901 0,05573676 ! DNA catabolic process GO:0006308 86 59 0,000 0,0515901 0,05571175 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,0515901 0,05568675 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05244202 0,05658094 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,05244202 0,05655558 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05244202 0,05653024 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05244202 0,05650492 ! camera-type eye development GO:0043010 116 60 0,000 0,05244202 0,05647963 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05244202 0,05645436 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05244202 0,05642911 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,0532932 0,05731938 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,0532932 0,05729377 ! mesoderm development GO:0007498 119 61 0,000 0,0532932 0,05726818 ! tRNA processing GO:0008033 89 61 0,000 0,0532932 0,05724261 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,0532932 0,05721707 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,0532932 0,05719155 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05414365 0,0580783 ! gonad development GO:0008406 98 62 0,000 0,05414365 0,05805242 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05414365 0,05802656 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05499336 0,05891097 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,05499336 0,05888475 ! detection of external stimulus GO:0009581 91 63 0,000 0,05499336 0,05885856 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05499336 0,05883239 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05499336 0,05880624 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05584234 0,05968755 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05584234 0,05966105 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05584234 0,05963457 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05584234 0,05960811 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05584234 0,05958167 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05584234 0,05955526 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05669059 0,06043312 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05669059 0,06040635 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05669059 0,06037961 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05669059 0,0603529 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05669059 0,0603262 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,0575381 0,061201 ! actin filament organization GO:0007015 148 66 0,000 0,0575381 0,06117395 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,0575381 0,06114693 ! extracellular matrix organization GO:0030198 133 66 0,000 0,0575381 0,06111994 ! secondary metabolic process GO:0019748 116 66 0,000 0,0575381 0,06109296 ! developmental maturation GO:0021700 116 66 0,000 0,0575381 0,06106602 ! cell projection assembly GO:0030031 120 66 0,000 0,0575381 0,06103909 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05838487 0,06191009 ! lung development GO:0030324 144 67 0,000 0,05838487 0,06188282 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,05838487 0,06185557 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05838487 0,06182835 ! hexose catabolic process GO:0019320 104 67 0,000 0,05838487 0,06180114 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05838487 0,06177397 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05838487 0,06174681 ! adaptive immune response GO:0002250 119 67 0,000 0,05838487 0,06171968 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05838487 0,06169258 ! amino acid transport GO:0006865 125 68 0,000 0,05923091 0,06255908 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05923091 0,06253163 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05923091 0,0625042 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05923091 0,0624768 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05923091 0,06244942 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05923091 0,06242207 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,06007623 0,0632852 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06007623 0,06325751 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06007623 0,06322983 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06007623 0,06320219 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06007623 0,06317456 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06092081 0,06403471 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,06092081 0,06400675 ! amine catabolic process GO:0009310 117 71 0,000 0,06176466 0,06486502 ! reproductive structure development GO:0048608 113 71 0,000 0,06176466 0,06483672 ! appendage development GO:0048736 136 71 0,000 0,06176466 0,06480844 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,06176466 0,06478019 ! B cell activation GO:0042113 160 71 0,000 0,06176466 0,06475197 ! regulation of immune effector process GO:0002697 137 71 0,000 0,06176466 0,06472376 ! acute inflammatory response GO:0002526 113 72 0,000 0,06260777 0,06557871 ! regulation of caspase activity GO:0043281 122 72 0,000 0,06260777 0,06555018 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06260777 0,06552166 ! carbohydrate transport GO:0008643 110 72 0,000 0,06260777 0,06549318 ! respiratory system development GO:0060541 153 72 0,000 0,06260777 0,06546471 ! learning or memory GO:0007611 147 73 0,000 0,06345016 0,06631672 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06345016 0,06628793 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06345016 0,06625916 ! axon guidance GO:0007411 139 73 0,000 0,06345016 0,06623041 ! fertilization GO:0009566 90 73 0,000 0,06345016 0,06620169 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06429182 0,06705077 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06429182 0,06702172 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06429182 0,06699269 ! exocytosis GO:0006887 133 74 0,000 0,06429182 0,06696369 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,06429182 0,06693472 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06429182 0,06690577 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,06429182 0,06687684 ! eye development GO:0001654 143 74 0,000 0,06429182 0,06684794 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06513276 0,06769305 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06513276 0,06766382 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06513276 0,06763462 ! rhythmic process GO:0048511 128 75 0,000 0,06513276 0,06760544 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06513276 0,06757629 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06597296 0,06841851 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06597296 0,06838903 ! defense response to bacterium GO:0042742 89 76 0,000 0,06597296 0,06835958 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06597296 0,06833015 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,06597296 0,06830075 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06681244 0,0691401 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,06681244 0,06911037 ! blood coagulation GO:0007596 146 78 0,000 0,06765119 0,0699479 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06765119 0,06991785 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,06765119 0,06988783 ! protein oligomerization GO:0051259 139 78 0,000 0,06765119 0,06985784 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06848921 0,07069286 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06848921 0,07066254 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06848921 0,07063225 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,06848921 0,07060199 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06848921 0,07057175 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06932651 0,07140393 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06932651 0,07137338 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06932651 0,07134285 ! protein import into nucleus GO:0006606 158 80 0,000 0,06932651 0,07131235 ! inorganic anion transport GO:0015698 138 80 0,000 0,06932651 0,07128188 ! T cell activation GO:0042110 168 81 0,000 0,07016309 0,07211123 ! response to hypoxia GO:0001666 171 81 0,000 0,07016309 0,07208044 ! digestion GO:0007586 112 81 0,000 0,07016309 0,07204967 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,07016309 0,07201894 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,07016309 0,07198822 ! nuclear import GO:0051170 161 81 0,000 0,07016309 0,07195754 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,07099894 0,07278374 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,07099894 0,07275274 ! response to drug GO:0042493 143 82 0,000 0,07099894 0,07272177 ! response to nutrient GO:0007584 125 82 0,000 0,07099894 0,07269083 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,07099894 0,07265991 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,07099894 0,07262901 ! response to oxygen levels GO:0070482 176 83 0,000 0,07183406 0,07345208 ! regulation of lyase activity GO:0051339 160 83 0,000 0,07183406 0,07342088 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07266847 0,07424218 ! hemostasis GO:0007599 158 84 0,000 0,07266847 0,07421067 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07266847 0,07417918 ! nucleosome assembly GO:0006334 122 85 0,000 0,07350215 0,07499838 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,07350215 0,07496658 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07433511 0,07578401 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07433511 0,07575191 ! chromatin assembly GO:0031497 124 86 0,000 0,07433511 0,07571984 ! mitochondrion organization GO:0007005 148 86 0,000 0,07433511 0,0756878 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07433511 0,07565578 ! amine transport GO:0015837 155 86 0,000 0,07433511 0,07562379 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07516735 0,07643814 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07516735 0,07640584 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07516735 0,07637358 ! cellular respiration GO:0045333 135 88 0,000 0,07599886 0,07718585 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07599886 0,07715328 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07599886 0,07712074 ! cellular defense response GO:0006968 114 89 0,000 0,07682966 0,07793093 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07682966 0,07789809 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,07682966 0,07786528 ! ossification GO:0001503 188 90 0,000 0,07765974 0,0786734 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07765974 0,07864029 ! sex differentiation GO:0007548 145 90 0,000 0,07765974 0,07860721 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07765974 0,07857415 ! bone development GO:0060348 189 91 0,000 0,0784891 0,0793799 ! sterol metabolic process GO:0016125 152 91 0,000 0,0784891 0,07934654 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,0784891 0,07931322 ! regulation of defense response GO:0031347 149 92 0,000 0,07931774 0,08011691 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07931774 0,08008329 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07931774 0,0800497 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,08014567 0,08085135 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,08014567 0,08081747 ! regulation of membrane potential GO:0042391 164 93 0,000 0,08014567 0,08078361 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,08014567 0,08074978 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,08097287 0,08154907 ! female pregnancy GO:0007565 164 94 0,000 0,08097287 0,08151495 ! transcription initiation GO:0006352 153 94 0,000 0,08097287 0,08148086 ! regulation of T cell activation GO:0050863 158 94 0,000 0,08097287 0,08144679 ! forebrain development GO:0030900 188 95 0,000 0,08179936 0,08224374 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,08179936 0,08220939 ! leukocyte differentiation GO:0002521 202 96 0,000 0,08262514 0,08300463 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,08262514 0,08296999 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,08262514 0,08293537 ! positive regulation of immune response GO:0050778 156 96 0,000 0,08262514 0,08290079 ! detection of stimulus GO:0051606 151 96 0,000 0,08262514 0,08286623 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0834502 0,08365882 ! hormone metabolic process GO:0042445 157 97 0,000 0,0834502 0,08362398 ! response to virus GO:0009615 160 98 0,000 0,08427454 0,08441488 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08427454 0,08437976 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08427454 0,08434466 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08509818 0,08513356 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,08509818 0,08509818