pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/11143-0-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 3,000 3,25E-11 1,185E-07 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 2,000 2,25E-07 4,104E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 2,000 2,811E-07 3,418E-04 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 2,000 3,458E-07 3,154E-04 ! negative regulation of intracellular transport GO:0032387 20 18 2,000 5,033E-07 3,672E-04 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 7,416E-07 4,509E-04 ! interphase GO:0051325 103 83 3,000 8,182E-07 4,264E-04 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 2,000 8,19E-07 3,735E-04 ! negative regulation of protein transport GO:0051224 34 30 2,000 2,487E-06 1,008E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 2,000 3,337E-06 1,217E-03 ! regulation of intracellular protein transport GO:0033157 43 40 2,000 6,019E-06 1,996E-03 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 7,506E-06 2,282E-03 ! regulation of protein export from nucleus GO:0046825 5 5 1,000 7,75E-06 2,175E-03 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 1,000 7,75E-06 2,019E-03 ! enucleate erythrocyte differentiation GO:0043353 7 5 1,000 7,75E-06 1,885E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 7,75E-06 1,767E-03 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 2,000 8,051E-06 1,728E-03 ! response to UV GO:0009411 59 45 2,000 8,621E-06 1,747E-03 ! nuclear periphery GO:0034399 60 49 2,000 1,117E-05 2,144E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,162E-05 2,119E-03 ! embryonic camera-type eye development GO:0031076 9 6 1,000 1,162E-05 2,018E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! retinoid X receptor binding GO:0046965 7 6 1,000 1,162E-05 1,927E-03 ! MutLalpha complex binding GO:0032405 8 6 1,000 1,162E-05 1,843E-03 ! DNA replication factor C complex GO:0005663 7 6 1,000 1,162E-05 1,766E-03 ! nucleosome disassembly GO:0006337 7 6 1,000 1,162E-05 1,695E-03 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! embryonic skeletal system development GO:0048706 59 50 2,000 1,187E-05 1,666E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 1,261E-05 1,704E-03 ! regulation of intracellular transport GO:0032386 57 52 2,000 1,337E-05 1,742E-03 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 1,000 1,626E-05 2,045E-03 ! dorsal/ventral axis specification GO:0009950 7 7 1,000 1,626E-05 1,977E-03 ! lysogeny GO:0030069 7 7 1,000 1,626E-05 1,913E-03 GO:0019047|provirus integration, ! mismatch repair complex binding GO:0032404 10 8 1,000 2,166E-05 2,47E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 2,276E-05 2,516E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 2,624E-05 2,816E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 2,748E-05 2,864E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 1,000 2,784E-05 2,821E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 2,000 2,875E-05 2,834E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 3,006E-05 2,885E-03 ! positive regulation of ligase activity GO:0051351 86 70 2,000 3,279E-05 3,067E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 3,478E-05 3,172E-03 ! regulation of mRNA processing GO:0050684 12 10 1,000 3,478E-05 3,095E-03 ! induction of an organ GO:0001759 12 10 1,000 3,478E-05 3,021E-03 ! trophectodermal cell differentiation GO:0001829 11 10 1,000 3,478E-05 2,951E-03 ! thyroid gland development GO:0030878 12 10 1,000 3,478E-05 2,884E-03 ! embryonic eye morphogenesis GO:0048048 14 10 1,000 3,478E-05 2,82E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 3,478E-05 2,758E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 2,000 4,034E-05 3,131E-03 ! kinase regulator activity GO:0019207 93 76 2,000 4,197E-05 3,19E-03 ! cytoplasmic sequestering of protein GO:0051220 12 11 1,000 4,249E-05 3,163E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 4,249E-05 3,1E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 1,000 4,249E-05 3,039E-03 ! DNA integration GO:0015074 11 11 1,000 4,249E-05 2,981E-03 ! regulation of ligase activity GO:0051340 95 78 2,000 4,537E-05 3,123E-03 ! regulation of protein transport GO:0051223 85 78 2,000 4,537E-05 3,065E-03 ! thymus development GO:0048538 13 12 1,000 5,096E-05 3,38E-03 ! blastocyst formation GO:0001825 13 12 1,000 5,096E-05 3,319E-03 ! embryonic placenta development GO:0001892 16 12 1,000 5,096E-05 3,261E-03 ! midbody GO:0030496 14 12 1,000 5,096E-05 3,205E-03 ! regulation of establishment of protein localization GO:0070201 90 83 2,000 5,464E-05 3,379E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 5,464E-05 3,322E-03 GO:0010498|proteasomal protein catabolic process, ! protein modification by small protein conjugation GO:0032446 103 85 2,000 5,867E-05 3,509E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 1,000 6,019E-05 3,541E-03 GO:0060675|ureteric bud morphogenesis, ! retinoic acid receptor binding GO:0042974 14 13 1,000 6,019E-05 3,485E-03 ! negative regulation of protein import into nucleus GO:0042308 13 13 1,000 6,019E-05 3,431E-03 ! DNA unwinding during replication GO:0006268 14 13 1,000 6,019E-05 3,378E-03 ! histone deacetylation GO:0016575 14 13 1,000 6,019E-05 3,327E-03 ! negative regulation of transport GO:0051051 98 86 2,000 6,076E-05 3,308E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 7,018E-05 3,765E-03 ! regulation of protein localization GO:0032880 99 91 2,000 7,193E-05 3,803E-03 ! cell cycle arrest GO:0007050 103 93 2,000 7,674E-05 3,999E-03 ! protein modification by small protein conjugation or removal GO:0070647 112 93 2,000 7,674E-05 3,943E-03 ! developmental induction GO:0031128 17 15 1,000 8,094E-05 4,101E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! DNA duplex unwinding GO:0032508 17 16 1,000 9,245E-05 4,62E-03 GO:0032392|DNA geometric change, ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 1,000 9,245E-05 4,558E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 1,000 9,245E-05 4,497E-03 ! response to light stimulus GO:0009416 131 100 2,000 9,525E-05 4,572E-03 ! protein amino acid deacetylation GO:0006476 19 18 1,000 1,177E-04 5,579E-03 ! spindle microtubule GO:0005876 27 18 1,000 1,177E-04 5,507E-03 ! embryonic organ morphogenesis GO:0048562 22 18 1,000 1,177E-04 5,437E-03 ! nuclear ubiquitin ligase complex GO:0000152 31 18 1,000 1,177E-04 5,369E-03 ! cellular macromolecular complex disassembly GO:0034623 23 19 1,000 1,315E-04 5,924E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,315E-04 5,852E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! histone deacetylase activity GO:0004407 20 19 1,000 1,315E-04 5,781E-03 GO:0033558|protein deacetylase activity, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 1,315E-04 5,712E-03 ! nuclear inner membrane GO:0005637 21 20 1,000 1,461E-04 6,269E-03 ! initiation of viral infection GO:0019059 22 20 1,000 1,461E-04 6,196E-03 ! activation of JUN kinase activity GO:0007257 22 20 1,000 1,461E-04 6,125E-03 ! positive regulation of protein catabolic process GO:0045732 23 21 1,000 1,614E-04 6,689E-03 ! axis specification GO:0009798 25 21 1,000 1,614E-04 6,614E-03 ! deacetylase activity GO:0019213 23 22 1,000 1,774E-04 7,191E-03 ! positive regulation of B cell activation GO:0050871 26 22 1,000 1,774E-04 7,112E-03 ! base-excision repair GO:0006284 33 22 1,000 1,774E-04 7,034E-03 ! regulation of chromosome organization GO:0033044 27 22 1,000 1,774E-04 6,959E-03 ! ureteric bud development GO:0001657 24 23 1,000 1,942E-04 7,536E-03 ! positive regulation of JUN kinase activity GO:0043507 25 23 1,000 1,942E-04 7,457E-03 ! growth cone GO:0030426 27 24 1,000 2,117E-04 8,046E-03 ! regulation of transcription factor import into nucleus GO:0042990 26 24 1,000 2,117E-04 7,963E-03 ! site of polarized growth GO:0030427 28 25 1,000 2,3E-04 8,562E-03 ! blastocyst development GO:0001824 27 26 1,000 2,491E-04 9,177E-03 ! regulation of JUN kinase activity GO:0043506 28 26 1,000 2,491E-04 9,086E-03 ! lysine N-acetyltransferase activity GO:0004468 29 26 1,000 2,491E-04 8,996E-03 GO:0004402|histone acetyltransferase activity, ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 2,491E-04 8,907E-03 ! histone deacetylase complex GO:0000118 29 26 1,000 2,491E-04 8,821E-03 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 2,491E-04 8,736E-03 ! liver development GO:0001889 33 27 1,000 2,688E-04 9,34E-03 ! fat cell differentiation GO:0045444 30 27 1,000 2,688E-04 9,252E-03 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 2,688E-04 9,166E-03 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 1,000 2,894E-04 9,774E-03 ! tissue homeostasis GO:0001894 31 28 1,000 2,894E-04 9,684E-03 GO:0048871|multicellular organismal homeostasis, ! negative regulation of phosphorylation GO:0042326 30 28 1,000 2,894E-04 9,596E-03 ! erythrocyte differentiation GO:0030218 35 29 1,000 3,106E-04 0,01020879 ! replication fork GO:0005657 42 29 1,000 3,106E-04 0,01011764 ! camera-type eye morphogenesis GO:0048593 36 29 1,000 3,106E-04 0,0100281 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 3,106E-04 9,94E-03 ! metanephros development GO:0001656 31 30 1,000 3,326E-04 0,0105519 ! maintenance of protein location in cell GO:0032507 32 31 1,000 3,554E-04 0,01117641 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 3,554E-04 0,01108089 GO:0045936|negative regulation of phosphate metabolic process, ! response to calcium ion GO:0051592 34 31 1,000 3,554E-04 0,01098698 ! macromolecular complex disassembly GO:0032984 37 31 1,000 3,554E-04 0,01089465 ! negative regulation of DNA binding GO:0043392 39 33 1,000 4,031E-04 0,01225452 ! embryonic organ development GO:0048568 41 33 1,000 4,031E-04 0,01215324 ! placenta development GO:0001890 39 33 1,000 4,031E-04 0,01205363 ! regulation of B cell activation GO:0050864 40 34 1,000 4,281E-04 0,01269608 ! regulation of protein import into nucleus GO:0042306 36 34 1,000 4,281E-04 0,01259369 ! erythrocyte homeostasis GO:0034101 40 34 1,000 4,281E-04 0,01249294 ! epithelial tube morphogenesis GO:0060562 38 34 1,000 4,281E-04 0,01239379 ! protein kinase inhibitor activity GO:0004860 37 34 1,000 4,281E-04 0,0122962 ! inner ear morphogenesis GO:0042472 46 35 1,000 4,538E-04 0,01293263 ! kinase inhibitor activity GO:0019210 47 35 1,000 4,538E-04 0,01283238 ! positive regulation of catabolic process GO:0009896 38 35 1,000 4,538E-04 0,01273367 ! maintenance of protein location GO:0045185 45 35 1,000 4,538E-04 0,01263646 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 4,802E-04 0,01327133 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 4,802E-04 0,01317155 GO:0050671|positive regulation of lymphocyte proliferation, ! maintenance of location in cell GO:0051651 38 36 1,000 4,802E-04 0,01307325 ! skeletal muscle fiber development GO:0048741 41 37 1,000 5,074E-04 0,0137106 ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 5,074E-04 0,01360979 GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of binding GO:0051100 44 38 1,000 5,353E-04 0,01425342 ! viral infectious cycle GO:0019058 40 38 1,000 5,353E-04 0,01415013 ! muscle fiber development GO:0048747 42 38 1,000 5,353E-04 0,01404833 ! cell fate specification GO:0001708 55 39 1,000 5,639E-04 0,01469409 ! embryonic skeletal system morphogenesis GO:0048704 46 39 1,000 5,639E-04 0,01458987 ! dorsal/ventral pattern formation GO:0009953 42 40 1,000 5,933E-04 0,01524147 ! induction of apoptosis by intracellular signals GO:0008629 56 41 1,000 6,234E-04 0,01590254 ! branching morphogenesis of a tube GO:0048754 54 41 1,000 6,234E-04 0,01579211 ! positive regulation of cell cycle GO:0045787 56 43 1,000 6,857E-04 0,01725221 ! ear morphogenesis GO:0042471 56 43 1,000 6,857E-04 0,01713405 ! epithelial cell differentiation GO:0030855 56 43 1,000 6,857E-04 0,01701749 ! histone modification GO:0016570 45 43 1,000 6,857E-04 0,0169025 ! nuclear matrix GO:0016363 56 45 1,000 7,51E-04 0,01838698 ! DNA-dependent DNA replication GO:0006261 66 45 1,000 7,51E-04 0,0182644 ! covalent chromatin modification GO:0016569 47 45 1,000 7,51E-04 0,01814344 ! eye morphogenesis GO:0048592 57 46 1,000 7,847E-04 0,0188333 ! regulation of JNK cascade GO:0046328 53 46 1,000 7,847E-04 0,0187102 ! JNK cascade GO:0007254 48 46 1,000 7,847E-04 0,01858871 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 1,000 8,192E-04 0,01927932 ! morphogenesis of a branching structure GO:0001763 70 47 1,000 8,192E-04 0,01915574 ! viral reproductive process GO:0022415 53 47 1,000 8,192E-04 0,01903373 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 1,000 8,543E-04 0,01972504 ! inner ear development GO:0048839 60 48 1,000 8,543E-04 0,01960099 ! chromatin remodeling complex GO:0016585 54 48 1,000 8,543E-04 0,01947848 ! regulation of gene expression, epigenetic GO:0040029 64 49 1,000 8,902E-04 0,02017045 ! maintenance of location GO:0051235 62 49 1,000 8,902E-04 0,02004594 ! nucleotide-excision repair GO:0006289 53 49 1,000 8,902E-04 0,01992296 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 8,902E-04 0,01980148 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 1,000 9,268E-04 0,02049059 ! endocrine system development GO:0035270 55 51 1,000 9,641E-04 0,02118716 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 1,002E-03 0,02189101 ! kidney development GO:0001822 55 52 1,000 1,002E-03 0,02176071 ! cellular component disassembly GO:0022411 69 52 1,000 1,002E-03 0,02163195 ! N-acetyltransferase activity GO:0008080 59 53 1,000 1,041E-03 0,0223361 ! viral reproduction GO:0016032 59 53 1,000 1,041E-03 0,02220548 ! regulation of protein catabolic process GO:0042176 56 53 1,000 1,041E-03 0,02207638 ! regulation of DNA replication GO:0006275 75 53 1,000 1,041E-03 0,02194877 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 1,041E-03 0,02182263 GO:0032944|regulation of mononuclear cell proliferation, ! double-stranded DNA binding GO:0003690 63 54 1,000 1,08E-03 0,02252044 ! regulation of cellular response to stress GO:0080135 79 59 1,000 1,288E-03 0,02670262 ! homeostasis of number of cells GO:0048872 67 59 1,000 1,288E-03 0,02655176 ! response to metal ion GO:0010038 65 60 1,000 1,332E-03 0,02729846 ! ear development GO:0043583 76 61 1,000 1,376E-03 0,02805119 ! camera-type eye development GO:0043010 69 61 1,000 1,376E-03 0,02789535 ! lung development GO:0030324 90 62 1,000 1,422E-03 0,02865065 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 1,422E-03 0,02849323 ! skeletal system morphogenesis GO:0048705 83 62 1,000 1,422E-03 0,02833752 ! negative regulation of cell growth GO:0030308 69 63 1,000 1,467E-03 0,02909204 ! urogenital system development GO:0001655 75 63 1,000 1,467E-03 0,02893479 ! negative regulation of protein kinase activity GO:0006469 78 64 1,000 1,514E-03 0,02969174 ! respiratory tube development GO:0030323 92 64 1,000 1,514E-03 0,02953296 ! response to unfolded protein GO:0006986 66 64 1,000 1,514E-03 0,02937587 ! nuclear hormone receptor binding GO:0035257 79 64 1,000 1,514E-03 0,02922044 ! N-acyltransferase activity GO:0016410 70 64 1,000 1,514E-03 0,02906665 ! negative regulation of cell size GO:0045792 71 65 1,000 1,561E-03 0,02981648 ! multicellular organism reproduction GO:0032504 71 65 1,000 1,561E-03 0,02966118 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 1,561E-03 0,0295075 ! response to inorganic substance GO:0010035 71 65 1,000 1,561E-03 0,0293554 ! negative regulation of kinase activity GO:0033673 79 65 1,000 1,561E-03 0,02920486 ! activation of MAPK activity GO:0000187 74 65 1,000 1,561E-03 0,02905585 ! acetyltransferase activity GO:0016407 73 65 1,000 1,561E-03 0,02890836 ! myeloid cell differentiation GO:0030099 78 66 1,000 1,609E-03 0,02964537 ! tube morphogenesis GO:0035239 84 66 1,000 1,609E-03 0,02949639 ! female pregnancy GO:0007565 78 67 1,000 1,658E-03 0,03023582 ! negative regulation of organelle organization GO:0010639 93 68 1,000 1,707E-03 0,03098054 ! respiratory system development GO:0060541 96 68 1,000 1,707E-03 0,03082717 ! skeletal muscle tissue development GO:0007519 75 69 1,000 1,757E-03 0,03157415 GO:0060538|skeletal muscle organ development, ! negative regulation of transferase activity GO:0051348 85 70 1,000 1,808E-03 0,03232623 ! hormone receptor binding GO:0051427 85 70 1,000 1,808E-03 0,03216854 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 1,808E-03 0,03201238 ! response to protein stimulus GO:0051789 73 70 1,000 1,808E-03 0,03185773 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 1,911E-03 0,03351986 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of MAPKKK cascade GO:0043408 82 72 1,000 1,911E-03 0,03335948 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 1,964E-03 0,03411765 ! phosphoinositide-mediated signaling GO:0048015 92 74 1,000 2,017E-03 0,03488057 ! ubiquitin ligase complex GO:0000151 91 74 1,000 2,017E-03 0,03471604 ! regulation of DNA binding GO:0051101 94 75 1,000 2,072E-03 0,03548079 ! positive regulation of cell activation GO:0050867 94 75 1,000 2,072E-03 0,03531499 ! negative regulation of growth GO:0045926 85 76 1,000 2,127E-03 0,0360815 ! regulation of neuron differentiation GO:0045664 96 76 1,000 2,127E-03 0,03591446 ! nucleosome organization GO:0034728 96 77 1,000 2,182E-03 0,03668269 ! positive regulation of protein modification process GO:0031401 100 78 1,000 2,238E-03 0,03745535 ! protein ubiquitination GO:0016567 95 78 1,000 2,238E-03 0,03728432 ! positive regulation of MAP kinase activity GO:0043406 89 79 1,000 2,295E-03 0,03805857 ! eye development GO:0001654 93 80 1,000 2,353E-03 0,03883709 ! regulation of catabolic process GO:0009894 87 80 1,000 2,353E-03 0,03866214 ! ossification GO:0001503 111 82 1,000 2,47E-03 0,04040663 ! bone development GO:0060348 112 83 1,000 2,53E-03 0,04119751 ! regulation of DNA metabolic process GO:0051052 139 84 1,000 2,59E-03 0,04199237 ! DNA recombination GO:0006310 147 84 1,000 2,59E-03 0,04180656 ! protein kinase binding GO:0019901 115 89 1,000 2,902E-03 0,04663206 ! gland development GO:0048732 108 89 1,000 2,902E-03 0,04642753 ! spindle GO:0005819 126 92 1,000 3,097E-03 0,04933294 ! structure-specific DNA binding GO:0043566 112 92 1,000 3,097E-03 0,04911845 ! anatomical structure homeostasis GO:0060249 121 92 1,000 3,097E-03 0,04890581 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 3,097E-03 0,04869501 ! morphogenesis of an epithelium GO:0002009 113 94 1,000 3,23E-03 0,05057491 GO:0060429|epithelium development, ! Wnt receptor signaling pathway GO:0016055 121 95 1,000 3,298E-03 0,05141435 ! in utero embryonic development GO:0001701 110 96 1,000 3,366E-03 0,05225697 ! cell fate commitment GO:0045165 118 98 1,000 3,505E-03 0,05418014 ! negative regulation of cellular component organization GO:0051129 132 99 1,000 3,575E-03 0,05503459 ! regulation of neurogenesis GO:0050767 123 100 1,000 3,646E-03 0,05589199 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 1,000 3,646E-03 0,05565813 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 3,646E-03 0,05542623 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 4,533E-03 0,06861332 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 4,533E-03 0,06832979 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 4,533E-03 0,0680486 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 4,533E-03 0,06776971 ! response to superoxide GO:0000303 5 5 0,000 4,533E-03 0,0674931 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 4,533E-03 0,06721874 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 4,533E-03 0,0669466 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 4,533E-03 0,06667665 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 4,533E-03 0,06640887 ! quinolinate metabolic process GO:0046874 5 5 0,000 4,533E-03 0,06614324 ! biotin binding GO:0009374 7 5 0,000 4,533E-03 0,06587972 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4,533E-03 0,06561829 ! tongue development GO:0043586 6 5 0,000 4,533E-03 0,06535893 ! nose development GO:0043584 5 5 0,000 4,533E-03 0,06510161 ! cell proliferation in forebrain GO:0021846 5 5 0,000 4,533E-03 0,06484631 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 4,533E-03 0,064593 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4,533E-03 0,06434167 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 4,533E-03 0,06409228 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 4,533E-03 0,06384482 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 4,533E-03 0,06359927 ! glycolipid transport GO:0046836 6 5 0,000 4,533E-03 0,06335559 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 4,533E-03 0,06311377 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 4,533E-03 0,0628738 ! neuron adhesion GO:0007158 5 5 0,000 4,533E-03 0,06263564 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 4,533E-03 0,06239928 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 4,533E-03 0,0621647 ! opioid peptide activity GO:0001515 6 5 0,000 4,533E-03 0,06193187 ! selenocysteine incorporation GO:0001514 5 5 0,000 4,533E-03 0,06170078 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 4,533E-03 0,06147141 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 4,533E-03 0,06124374 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 4,533E-03 0,06101775 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 4,533E-03 0,06079342 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 4,533E-03 0,06057073 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,533E-03 0,06034967 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 4,533E-03 0,06013021 ! clathrin coat assembly GO:0048268 6 5 0,000 4,533E-03 0,05991235 ! cerebral cortex cell migration GO:0021795 5 5 0,000 4,533E-03 0,05969606 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 4,533E-03 0,05948133 ! membrane hyperpolarization GO:0060081 5 5 0,000 4,533E-03 0,05926813 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 4,533E-03 0,05905646 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4,533E-03 0,0588463 ! translation repressor activity GO:0030371 8 5 0,000 4,533E-03 0,05863762 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 4,533E-03 0,05843042 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 4,533E-03 0,05822468 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4,533E-03 0,05802038 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 4,533E-03 0,05781751 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 4,533E-03 0,05761606 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 4,533E-03 0,057416 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4,533E-03 0,05721733 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4,533E-03 0,05702003 ! microfibril GO:0001527 5 5 0,000 4,533E-03 0,05682409 ! troponin I binding GO:0031013 5 5 0,000 4,533E-03 0,05662948 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 4,533E-03 0,05643621 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 4,533E-03 0,05624425 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4,533E-03 0,05605359 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 4,533E-03 0,05586422 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4,533E-03 0,05567612 ! protein lipoylation GO:0009249 14 5 0,000 4,533E-03 0,05548929 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 4,533E-03 0,05530371 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4,533E-03 0,05511936 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 4,533E-03 0,05493624 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 4,533E-03 0,05475433 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4,533E-03 0,05457363 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4,533E-03 0,05439411 ! glutamate catabolic process GO:0006538 6 5 0,000 4,533E-03 0,05421577 ! microvillus organization GO:0032528 5 5 0,000 4,533E-03 0,05403859 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 4,533E-03 0,05386257 ! tyrosine catabolic process GO:0006572 5 5 0,000 4,533E-03 0,05368769 ! response to pH GO:0009268 5 5 0,000 4,533E-03 0,05351395 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 4,533E-03 0,05334132 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 4,533E-03 0,0531698 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4,533E-03 0,05299939 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,533E-03 0,05283006 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 4,533E-03 0,05266181 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,533E-03 0,05249463 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 4,533E-03 0,05232851 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 4,533E-03 0,05216344 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 4,533E-03 0,0519994 ! anaerobic glycolysis GO:0019642 5 5 0,000 4,533E-03 0,05183639 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 4,533E-03 0,0516744 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 4,533E-03 0,05151342 ! peroxisomal matrix GO:0005782 5 5 0,000 4,533E-03 0,05135344 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4,533E-03 0,05119446 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 4,533E-03 0,05103645 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4,533E-03 0,05087941 ! multivesicular body GO:0005771 5 5 0,000 4,533E-03 0,05072334 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 4,533E-03 0,05056822 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 4,533E-03 0,05041405 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 4,533E-03 0,05026082 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 4,533E-03 0,05010851 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 4,533E-03 0,04995713 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 4,533E-03 0,04980665 ! epithelial cell maturation GO:0002070 14 5 0,000 4,533E-03 0,04965708 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 4,533E-03 0,04950841 ! muscle thin filament assembly GO:0030240 5 5 0,000 4,533E-03 0,04936062 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 4,533E-03 0,04921372 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 4,533E-03 0,04906768 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 4,533E-03 0,04892251 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 4,533E-03 0,0487782 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,533E-03 0,04863473 ! positive regulation of translational initiation GO:0045948 6 5 0,000 4,533E-03 0,04849211 ! nonhomologous end joining complex GO:0070419 6 5 0,000 4,533E-03 0,04835032 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 4,533E-03 0,04820936 ! ATPase activator activity GO:0001671 5 5 0,000 4,533E-03 0,04806921 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4,533E-03 0,04792988 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 4,533E-03 0,04779136 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 4,533E-03 0,04765363 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 4,533E-03 0,04751669 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 4,533E-03 0,04738054 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 4,533E-03 0,04724517 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 4,533E-03 0,04711057 ! cardiac myofibril assembly GO:0055003 5 5 0,000 4,533E-03 0,04697673 ! anterograde axon cargo transport GO:0008089 6 5 0,000 4,533E-03 0,04684365 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,533E-03 0,04671132 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4,533E-03 0,04657974 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4,533E-03 0,0464489 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 4,533E-03 0,04631879 ! protein localization to telomere GO:0070198 7 5 0,000 4,533E-03 0,04618941 ! response to exogenous dsRNA GO:0043330 5 5 0,000 4,533E-03 0,04606075 ! MutSalpha complex binding GO:0032407 7 5 0,000 4,533E-03 0,0459328 ! bile acid biosynthetic process GO:0006699 5 5 0,000 4,533E-03 0,04580557 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 4,533E-03 0,04567903 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,533E-03 0,04555319 ! nerve growth factor binding GO:0048406 7 5 0,000 4,533E-03 0,04542805 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 4,533E-03 0,04530359 ! high-density lipoprotein binding GO:0008035 6 5 0,000 4,533E-03 0,04517981 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 4,533E-03 0,0450567 ! transcription initiation factor activity GO:0016986 5 5 0,000 4,533E-03 0,04493426 ! gas homeostasis GO:0033483 5 5 0,000 4,533E-03 0,04481249 ! Schwann cell development GO:0014044 5 5 0,000 4,533E-03 0,04469138 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 4,533E-03 0,04457091 ! cyclohydrolase activity GO:0019238 5 5 0,000 4,533E-03 0,0444511 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,533E-03 0,04433193 ! response to pheromone GO:0019236 5 5 0,000 4,533E-03 0,04421339 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 4,533E-03 0,04409549 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 4,533E-03 0,04397822 ! rhombomere development GO:0021546 6 5 0,000 4,533E-03 0,04386156 ! alanine transport GO:0032328 6 5 0,000 4,533E-03 0,04374553 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 4,533E-03 0,0436301 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 4,533E-03 0,04351529 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 4,533E-03 0,04340107 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 4,533E-03 0,04328746 ! regulation of meiosis GO:0040020 6 5 0,000 4,533E-03 0,04317444 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 4,533E-03 0,043062 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 4,533E-03 0,04295015 ! lymphocyte costimulation GO:0031294 5 5 0,000 4,533E-03 0,04283888 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 4,533E-03 0,04272819 ! RS domain binding GO:0050733 6 5 0,000 4,533E-03 0,04261806 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 4,533E-03 0,04250851 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 4,533E-03 0,04239951 ! B cell homeostasis GO:0001782 6 5 0,000 4,533E-03 0,04229107 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4,533E-03 0,04218319 ! anaphase GO:0051322 7 5 0,000 4,533E-03 0,04207585 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 4,533E-03 0,04196906 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4,533E-03 0,04186281 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 4,533E-03 0,04175709 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4,533E-03 0,04165191 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 4,533E-03 0,04154726 ! diuresis GO:0030146 5 5 0,000 4,533E-03 0,04144313 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 4,533E-03 0,04133952 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4,533E-03 0,04123643 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4,533E-03 0,04113385 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 4,533E-03 0,04103178 ! GTP-Rho binding GO:0017049 5 5 0,000 4,533E-03 0,04093022 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4,533E-03 0,04082916 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,533E-03 0,04072859 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 4,533E-03 0,04062852 ! brown fat cell differentiation GO:0050873 5 5 0,000 4,533E-03 0,04052894 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,533E-03 0,04042985 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4,533E-03 0,04033124 ! TAP complex GO:0042825 5 5 0,000 4,533E-03 0,04023311 ! platelet dense granule GO:0042827 6 5 0,000 4,533E-03 0,04013546 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4,533E-03 0,04003828 ! secretory granule organization GO:0033363 5 5 0,000 4,533E-03 0,03994157 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 4,533E-03 0,03984532 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4,533E-03 0,03974954 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 4,533E-03 0,03965422 ! lamin binding GO:0005521 8 5 0,000 4,533E-03 0,03955935 ! aldehyde-lyase activity GO:0016832 6 5 0,000 4,533E-03 0,03946494 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,533E-03 0,03937097 ! neural plate morphogenesis GO:0001839 6 5 0,000 4,533E-03 0,03927746 ! cyclosporin A binding GO:0016018 6 5 0,000 4,533E-03 0,03918438 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4,533E-03 0,03909175 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 4,533E-03 0,03899955 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 4,533E-03 0,03890779 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 4,533E-03 0,03881645 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 4,533E-03 0,03872555 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 4,533E-03 0,03863507 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 4,533E-03 0,03854501 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 4,533E-03 0,03845537 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 4,533E-03 0,03836615 ! organ or tissue specific immune response GO:0002251 6 5 0,000 4,533E-03 0,03827734 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4,533E-03 0,03818894 ! retina homeostasis GO:0001895 5 5 0,000 4,533E-03 0,03810094 ! prepulse inhibition GO:0060134 8 5 0,000 4,533E-03 0,03801335 ! maternal placenta development GO:0001893 5 5 0,000 4,533E-03 0,03792617 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 4,533E-03 0,03783938 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 4,533E-03 0,03775299 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4,533E-03 0,03766699 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 4,533E-03 0,03758138 ! protein palmitoylation GO:0018345 5 5 0,000 4,533E-03 0,03749617 ! protein amino acid prenylation GO:0018346 6 5 0,000 4,533E-03 0,03741133 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 4,533E-03 0,03732688 ! stem cell division GO:0017145 6 5 0,000 4,533E-03 0,03724281 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4,533E-03 0,03715912 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 4,533E-03 0,0370758 ! organ regeneration GO:0031100 6 5 0,000 4,533E-03 0,03699286 ! lymphocyte apoptosis GO:0070227 6 5 0,000 4,533E-03 0,03691029 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 4,533E-03 0,03682808 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4,533E-03 0,03674624 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 4,533E-03 0,03666477 ! acyl carrier activity GO:0000036 5 5 0,000 4,533E-03 0,03658365 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 4,533E-03 0,03650289 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 4,533E-03 0,03642249 ! phagocytic vesicle GO:0045335 5 5 0,000 4,533E-03 0,03634244 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4,533E-03 0,03626274 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4,533E-03 0,03618339 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 4,533E-03 0,03610439 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4,533E-03 0,03602573 ! polyol transport GO:0015791 8 5 0,000 4,533E-03 0,03594741 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 4,533E-03 0,03586943 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 4,533E-03 0,03579179 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 4,533E-03 0,03571449 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 4,533E-03 0,03563752 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4,533E-03 0,03556088 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 4,533E-03 0,03548457 ! ethanol metabolic process GO:0006067 6 5 0,000 4,533E-03 0,03540858 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 4,533E-03 0,03533293 ! cobalt ion transport GO:0006824 5 5 0,000 4,533E-03 0,03525759 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 4,533E-03 0,03518257 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 4,533E-03 0,03510787 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 4,533E-03 0,03503349 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 4,533E-03 0,03495943 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 4,533E-03 0,03488567 ! sterol carrier activity GO:0005498 6 5 0,000 4,533E-03 0,03481223 ! adaptation of signaling pathway GO:0022401 6 5 0,000 4,533E-03 0,03473909 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 4,533E-03 0,03466627 ! response to acid GO:0001101 7 5 0,000 4,533E-03 0,03459374 ! fibril organization GO:0043206 5 5 0,000 4,533E-03 0,03452152 ! malate metabolic process GO:0006108 6 5 0,000 4,533E-03 0,0344496 ! regulation of dopamine uptake GO:0051584 7 5 0,000 4,533E-03 0,03437798 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 4,533E-03 0,03430666 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 4,533E-03 0,03423563 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 4,533E-03 0,03416489 ! protein maturation by protein folding GO:0022417 5 5 0,000 4,533E-03 0,03409445 ! activation of protein kinase B activity GO:0032148 15 5 0,000 4,533E-03 0,0340243 ! origin recognition complex GO:0000808 5 5 0,000 4,533E-03 0,03395443 ! neurexin binding GO:0042043 6 5 0,000 4,533E-03 0,03388485 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 4,533E-03 0,03381556 ! protein amino acid dealkylation GO:0008214 5 5 0,000 4,533E-03 0,03374655 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 4,533E-03 0,03367782 ! lipoic acid binding GO:0031405 5 5 0,000 4,533E-03 0,03360937 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 4,533E-03 0,03354119 ! lithium ion binding GO:0031403 6 5 0,000 4,533E-03 0,0334733 ! grooming behavior GO:0007625 7 5 0,000 4,533E-03 0,03340567 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 4,533E-03 0,03333832 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4,533E-03 0,03327125 ! lymph vessel development GO:0001945 6 5 0,000 4,533E-03 0,03320444 ! bicarbonate transport GO:0015701 5 5 0,000 4,533E-03 0,03313789 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 4,533E-03 0,03307162 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 4,533E-03 0,03300561 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 4,533E-03 0,03293986 ! endothelial cell proliferation GO:0001935 8 5 0,000 4,533E-03 0,03287437 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 4,533E-03 0,03280914 ! dorsal spinal cord development GO:0021516 6 5 0,000 4,533E-03 0,03274418 ! activation of MAPKKK activity GO:0000185 5 5 0,000 4,533E-03 0,03267946 ! synaptic vesicle maturation GO:0016188 6 5 0,000 4,533E-03 0,03261501 ! sphingoid catabolic process GO:0046521 5 5 0,000 4,533E-03 0,03255081 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4,533E-03 0,03248685 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4,533E-03 0,03242315 ! intercellular canaliculus GO:0046581 5 5 0,000 4,533E-03 0,0323597 ! dopamine binding GO:0035240 7 5 0,000 4,533E-03 0,0322965 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 4,533E-03 0,03223355 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 4,533E-03 0,03217083 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 4,533E-03 0,03210837 ! amine oxidase activity GO:0008131 7 5 0,000 4,533E-03 0,03204614 ! monocyte activation GO:0042117 9 5 0,000 4,533E-03 0,03198416 ! negative regulation of protein binding GO:0032091 5 5 0,000 4,533E-03 0,03192241 ! regulation of response to food GO:0032095 5 5 0,000 4,533E-03 0,0318609 ! response to food GO:0032094 6 5 0,000 4,533E-03 0,03179963 ! positive regulation of protein binding GO:0032092 5 5 0,000 4,533E-03 0,0317386 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 4,533E-03 0,0316778 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 4,533E-03 0,03161723 ! hedgehog receptor activity GO:0008158 5 5 0,000 4,533E-03 0,03155689 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4,533E-03 0,03149678 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 4,533E-03 0,0314369 ! purine salvage GO:0043101 7 5 0,000 4,533E-03 0,03137725 ! small-subunit processome GO:0032040 5 5 0,000 4,533E-03 0,03131782 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 4,533E-03 0,03125862 ! ciliary rootlet GO:0035253 5 5 0,000 4,533E-03 0,03119964 ! myosin heavy chain binding GO:0032036 5 5 0,000 4,533E-03 0,03114088 ! nucleobase transport GO:0015851 5 5 0,000 4,533E-03 0,03108235 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 4,533E-03 0,03102403 ! GPI anchor binding GO:0034235 6 5 0,000 4,533E-03 0,03096593 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,533E-03 0,03090805 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 4,533E-03 0,03085039 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 4,533E-03 0,03079294 ! basic amino acid transport GO:0015802 5 5 0,000 4,533E-03 0,0307357 ! dendritic shaft GO:0043198 5 5 0,000 4,533E-03 0,03067868 ! terminal button GO:0043195 7 5 0,000 4,533E-03 0,03062187 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4,533E-03 0,03056527 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 4,533E-03 0,03050887 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 4,533E-03 0,03045269 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 4,533E-03 0,03039671 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 4,533E-03 0,03034093 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 4,533E-03 0,03028536 ! response to UV-C GO:0010225 15 5 0,000 4,533E-03 0,03023 ! positive regulation of organ growth GO:0046622 5 5 0,000 4,533E-03 0,03017483 ! response to arsenic GO:0046685 6 5 0,000 4,533E-03 0,03011987 ! IgE binding GO:0019863 5 5 0,000 4,533E-03 0,03006511 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 4,533E-03 0,03001054 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 4,533E-03 0,02995618 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 4,533E-03 0,02990201 ! response to copper ion GO:0046688 5 5 0,000 4,533E-03 0,02984803 ! response to cadmium ion GO:0046686 5 5 0,000 4,533E-03 0,02979425 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 4,533E-03 0,02974066 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 4,533E-03 0,02968727 ! protein autoprocessing GO:0016540 6 5 0,000 4,533E-03 0,02963407 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4,533E-03 0,02958105 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4,533E-03 0,02952823 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4,533E-03 0,0294756 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 4,533E-03 0,02942315 ! mitotic recombination GO:0006312 15 5 0,000 4,533E-03 0,02937089 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 4,533E-03 0,02931881 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,533E-03 0,02926692 ! membrane to membrane docking GO:0022614 5 5 0,000 4,533E-03 0,02921521 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 4,533E-03 0,02916368 ! translation activator activity GO:0008494 5 5 0,000 4,533E-03 0,02911234 ! somatostatin receptor activity GO:0004994 5 5 0,000 4,533E-03 0,02906118 ! melanocortin receptor activity GO:0004977 6 5 0,000 4,533E-03 0,02901019 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 4,533E-03 0,02895939 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 4,533E-03 0,02890876 ! salivary gland morphogenesis GO:0007435 5 5 0,000 4,533E-03 0,02885831 ! galactosidase activity GO:0015925 5 5 0,000 4,533E-03 0,02880803 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 4,533E-03 0,02875793 ! cellular response to nutrient GO:0031670 5 5 0,000 4,533E-03 0,028708 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4,533E-03 0,02865825 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 4,533E-03 0,02860867 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 4,533E-03 0,02855926 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 4,533E-03 0,02851002 ! A band GO:0031672 5 5 0,000 4,533E-03 0,02846094 ! heat generation GO:0031649 5 5 0,000 4,533E-03 0,02841204 ! flagellum organization GO:0043064 5 5 0,000 4,533E-03 0,02836331 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 4,533E-03 0,02831474 ! disaccharide metabolic process GO:0005984 6 5 0,000 4,533E-03 0,02826634 ! glycogen catabolic process GO:0005980 16 5 0,000 4,533E-03 0,0282181 ! dopamine biosynthetic process GO:0042416 6 5 0,000 4,533E-03 0,02817003 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 4,533E-03 0,02812212 ! chromocenter GO:0010369 5 5 0,000 4,533E-03 0,02807438 ! glial cell migration GO:0008347 5 5 0,000 4,533E-03 0,02802679 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 4,533E-03 0,02797937 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 4,533E-03 0,02793211 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4,533E-03 0,02788501 ! growth hormone receptor binding GO:0005131 5 5 0,000 4,533E-03 0,02783806 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4,533E-03 0,02779128 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 4,533E-03 0,02774465 ! aminomethyltransferase activity GO:0004047 5 5 0,000 4,533E-03 0,02769817 ! aminoacylase activity GO:0004046 5 5 0,000 4,533E-03 0,02765185 ! penetration of zona pellucida GO:0007341 6 5 0,000 4,533E-03 0,02760569 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 4,533E-03 0,02755968 ! nucleus localization GO:0051647 5 5 0,000 4,533E-03 0,02751383 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 4,533E-03 0,02746812 ! carnitine metabolic process GO:0009437 5 5 0,000 4,533E-03 0,02742257 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,437E-03 0,03283857 ! regulation of helicase activity GO:0051095 6 6 0,000 5,437E-03 0,03278429 ! response to oxygen radical GO:0000305 6 6 0,000 5,437E-03 0,03273019 ! positive regulation of axon extension GO:0045773 7 6 0,000 5,437E-03 0,03267627 ! forebrain neuron differentiation GO:0021879 6 6 0,000 5,437E-03 0,03262252 ! forebrain regionalization GO:0021871 7 6 0,000 5,437E-03 0,03256896 ! meiotic prophase I GO:0007128 7 6 0,000 5,437E-03 0,03251556 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 5,437E-03 0,03246235 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 5,437E-03 0,0324093 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 5,437E-03 0,03235643 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 5,437E-03 0,03230374 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 5,437E-03 0,03225121 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 5,437E-03 0,03219885 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 5,437E-03 0,03214667 ! protein amino acid sulfation GO:0006477 9 6 0,000 5,437E-03 0,03209465 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 5,437E-03 0,0320428 ! establishment of tissue polarity GO:0007164 8 6 0,000 5,437E-03 0,03199112 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 5,437E-03 0,0319396 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 5,437E-03 0,03188825 ! hexokinase activity GO:0004396 7 6 0,000 5,437E-03 0,03183707 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 5,437E-03 0,03178605 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 5,437E-03 0,03173519 ! Notch receptor processing GO:0007220 7 6 0,000 5,437E-03 0,0316845 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 5,437E-03 0,03163396 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 5,437E-03 0,03158359 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 5,437E-03 0,03153338 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 5,437E-03 0,03148332 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 5,437E-03 0,03143343 ! neurofilament GO:0005883 7 6 0,000 5,437E-03 0,03138369 ! glial cell fate commitment GO:0021781 7 6 0,000 5,437E-03 0,03133411 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 5,437E-03 0,03128469 ! dynactin complex GO:0005869 7 6 0,000 5,437E-03 0,03123542 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 5,437E-03 0,03118631 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 5,437E-03 0,03113735 ! oocyte maturation GO:0001556 6 6 0,000 5,437E-03 0,03108855 ! DNA replication origin binding GO:0003688 6 6 0,000 5,437E-03 0,0310399 ! reflex GO:0060004 10 6 0,000 5,437E-03 0,0309914 ! positive regulation of glycolysis GO:0045821 6 6 0,000 5,437E-03 0,03094305 ! parathyroid gland development GO:0060017 6 6 0,000 5,437E-03 0,03089485 ! anagen GO:0042640 7 6 0,000 5,437E-03 0,0308468 ! protein-cofactor linkage GO:0018065 15 6 0,000 5,437E-03 0,0307989 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 5,437E-03 0,03075115 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 5,437E-03 0,03070355 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 5,437E-03 0,0306561 ! skeletal myofibril assembly GO:0014866 6 6 0,000 5,437E-03 0,03060879 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 5,437E-03 0,03056162 ! cysteine metabolic process GO:0006534 7 6 0,000 5,437E-03 0,03051461 ! glycine catabolic process GO:0006546 6 6 0,000 5,437E-03 0,03046773 ! adenohypophysis development GO:0021984 6 6 0,000 5,437E-03 0,030421 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 5,437E-03 0,03037442 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 5,437E-03 0,03032797 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 5,437E-03 0,03028167 ! microtubule nucleation GO:0007020 7 6 0,000 5,437E-03 0,03023551 ! proline biosynthetic process GO:0006561 8 6 0,000 5,437E-03 0,03018949 ! tryptophan metabolic process GO:0006568 6 6 0,000 5,437E-03 0,03014361 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 5,437E-03 0,03009787 ! thyroid hormone generation GO:0006590 6 6 0,000 5,437E-03 0,03005226 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 5,437E-03 0,0300068 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 5,437E-03 0,02996147 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 5,437E-03 0,02991628 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 5,437E-03 0,02987123 ! sister chromatid cohesion GO:0007062 6 6 0,000 5,437E-03 0,02982631 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 5,437E-03 0,02978152 ! positive regulation of transporter activity GO:0032411 8 6 0,000 5,437E-03 0,02973687 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 5,437E-03 0,02969236 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 5,437E-03 0,02964797 ! p53 binding GO:0002039 6 6 0,000 5,437E-03 0,02960372 ! demethylase activity GO:0032451 6 6 0,000 5,437E-03 0,0295596 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 5,437E-03 0,02951562 ! regulation of platelet activation GO:0010543 7 6 0,000 5,437E-03 0,02947176 ! lipid phosphatase activity GO:0042577 7 6 0,000 5,437E-03 0,02942803 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 5,437E-03 0,02938444 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 5,437E-03 0,02934097 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 5,437E-03 0,02929763 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 5,437E-03 0,02925442 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 5,437E-03 0,02921133 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 5,437E-03 0,02916837 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 5,437E-03 0,02912554 ! LIM domain binding GO:0030274 7 6 0,000 5,437E-03 0,02908284 ! negative regulation of translational initiation GO:0045947 6 6 0,000 5,437E-03 0,02904025 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 5,437E-03 0,0289978 ! 5S class rRNA transcription GO:0042791 6 6 0,000 5,437E-03 0,02895547 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 5,437E-03 0,02891326 ! axon guidance receptor activity GO:0008046 6 6 0,000 5,437E-03 0,02887117 ! zinc ion homeostasis GO:0055069 7 6 0,000 5,437E-03 0,02882921 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 5,437E-03 0,02878736 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 5,437E-03 0,02874564 ! protein targeting to lysosome GO:0006622 6 6 0,000 5,437E-03 0,02870404 ! hyaluronan metabolic process GO:0030212 8 6 0,000 5,437E-03 0,02866256 ! protein retention in ER lumen GO:0006621 6 6 0,000 5,437E-03 0,0286212 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 5,437E-03 0,02857996 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 5,437E-03 0,02853884 ! dynein binding GO:0045502 6 6 0,000 5,437E-03 0,02849784 ! regulation of dendrite development GO:0050773 6 6 0,000 5,437E-03 0,02845695 ! peptidyl-arginine modification GO:0018195 6 6 0,000 5,437E-03 0,02841618 ! eating behavior GO:0042755 7 6 0,000 5,437E-03 0,02837553 ! protein localization to chromosome GO:0034502 8 6 0,000 5,437E-03 0,02833499 ! Hsp90 protein binding GO:0051879 7 6 0,000 5,437E-03 0,02829457 ! glycolipid binding GO:0051861 7 6 0,000 5,437E-03 0,02825427 ! mast cell activation GO:0045576 6 6 0,000 5,437E-03 0,02821407 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 5,437E-03 0,028174 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,437E-03 0,02813403 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 5,437E-03 0,02809418 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 5,437E-03 0,02805445 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 5,437E-03 0,02801482 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 5,437E-03 0,02797531 ! lipoxygenase activity GO:0016165 6 6 0,000 5,437E-03 0,02793591 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 5,437E-03 0,02789662 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 5,437E-03 0,02785744 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 5,437E-03 0,02781836 ! DNA replication factor A complex GO:0005662 7 6 0,000 5,437E-03 0,0277794 ! establishment of chromosome localization GO:0051303 15 6 0,000 5,437E-03 0,02774055 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 5,437E-03 0,02770181 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 5,437E-03 0,02766317 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 5,437E-03 0,02762464 ! chromatin assembly complex GO:0005678 16 6 0,000 5,437E-03 0,02758622 ! sex chromatin GO:0001739 6 6 0,000 5,437E-03 0,02754791 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 5,437E-03 0,0275097 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 5,437E-03 0,0274716 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! SAP kinase activity GO:0016909 7 6 0,000 5,437E-03 0,0274336 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 5,437E-03 0,02739571 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 5,437E-03 0,02735792 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 5,437E-03 0,02732024 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 5,437E-03 0,02728266 ! phosphatidylserine binding GO:0001786 6 6 0,000 5,437E-03 0,02724518 ! alpha-mannosidase activity GO:0004559 8 6 0,000 5,437E-03 0,02720781 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 5,437E-03 0,02717054 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 5,437E-03 0,02713337 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 5,437E-03 0,0270963 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 5,437E-03 0,02705934 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 5,437E-03 0,02702247 ! leading edge membrane GO:0031256 8 6 0,000 5,437E-03 0,02698571 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 5,437E-03 0,02694904 ! CARD domain binding GO:0050700 6 6 0,000 5,437E-03 0,02691248 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 5,437E-03 0,02687601 ! COPII vesicle coat GO:0030127 7 6 0,000 5,437E-03 0,02683964 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 5,437E-03 0,02680337 ! glutathione biosynthetic process GO:0006750 7 6 0,000 5,437E-03 0,0267672 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 5,437E-03 0,02673112 ! positive regulation of epidermis development GO:0045684 8 6 0,000 5,437E-03 0,02669515 ! proteasome regulator activity GO:0010860 6 6 0,000 5,437E-03 0,02665927 ! ceramidase activity GO:0017040 6 6 0,000 5,437E-03 0,02662348 ! antibiotic transport GO:0042891 7 6 0,000 5,437E-03 0,02658779 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 5,437E-03 0,0265522 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 5,437E-03 0,0265167 ! sodium channel regulator activity GO:0017080 6 6 0,000 5,437E-03 0,0264813 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 5,437E-03 0,02644599 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 5,437E-03 0,02641078 ! response to fluid shear stress GO:0034405 6 6 0,000 5,437E-03 0,02637566 ! lymph node development GO:0048535 6 6 0,000 5,437E-03 0,02634063 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 5,437E-03 0,0263057 ! triglyceride catabolic process GO:0019433 15 6 0,000 5,437E-03 0,02627085 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 5,437E-03 0,0262361 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 5,437E-03 0,02620145 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 5,437E-03 0,02616688 ! negative regulation of lipase activity GO:0060192 6 6 0,000 5,437E-03 0,0261324 ! activation of innate immune response GO:0002218 6 6 0,000 5,437E-03 0,02609802 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 5,437E-03 0,02606372 ! sarcoglycan complex GO:0016012 8 6 0,000 5,437E-03 0,02602952 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 5,437E-03 0,02599541 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 5,437E-03 0,02596138 ! neural plate development GO:0001840 7 6 0,000 5,437E-03 0,02592744 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 5,437E-03 0,0258936 ! catecholamine transport GO:0051937 6 6 0,000 5,437E-03 0,02585984 ! ether hydrolase activity GO:0016803 7 6 0,000 5,437E-03 0,02582616 ! FACIT collagen GO:0005593 6 6 0,000 5,437E-03 0,02579258 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 5,437E-03 0,02575908 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 5,437E-03 0,02572567 ! collagen type IV GO:0005587 6 6 0,000 5,437E-03 0,02569235 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 5,437E-03 0,02565911 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 5,437E-03 0,02562596 ! drug metabolic process GO:0017144 6 6 0,000 5,437E-03 0,0255929 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 5,437E-03 0,02555992 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 5,437E-03 0,02552702 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 5,437E-03 0,02549421 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 5,437E-03 0,02546148 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 5,437E-03 0,02542884 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 5,437E-03 0,02539628 ! cellular anion homeostasis GO:0030002 6 6 0,000 5,437E-03 0,0253638 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 5,437E-03 0,02533141 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 5,437E-03 0,0252991 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 5,437E-03 0,02526687 ! behavioral response to cocaine GO:0048148 9 6 0,000 5,437E-03 0,02523473 ! translation initiation factor binding GO:0031369 6 6 0,000 5,437E-03 0,02520266 ! nucleotide-sugar transport GO:0015780 6 6 0,000 5,437E-03 0,02517068 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 5,437E-03 0,02513878 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 5,437E-03 0,02510695 ! quaternary ammonium group binding GO:0050997 7 6 0,000 5,437E-03 0,02507521 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 5,437E-03 0,02504355 ! reproductive behavior GO:0019098 8 6 0,000 5,437E-03 0,02501197 ! response to growth hormone stimulus GO:0060416 7 6 0,000 5,437E-03 0,02498047 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 5,437E-03 0,02494905 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 5,437E-03 0,02491771 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 5,437E-03 0,02488644 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 5,437E-03 0,02485526 ! induction of positive chemotaxis GO:0050930 7 6 0,000 5,437E-03 0,02482415 ! cohesin complex GO:0008278 6 6 0,000 5,437E-03 0,02479312 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 5,437E-03 0,02476216 ! citrate metabolic process GO:0006101 7 6 0,000 5,437E-03 0,02473129 ! myelin sheath GO:0043209 8 6 0,000 5,437E-03 0,02470049 ! phototransduction, visible light GO:0007603 6 6 0,000 5,437E-03 0,02466977 ! opsonization GO:0008228 7 6 0,000 5,437E-03 0,02463912 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 5,437E-03 0,02460855 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 5,437E-03 0,02457806 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 5,437E-03 0,02454764 ! regulation of potassium ion transport GO:0043266 8 6 0,000 5,437E-03 0,0245173 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 5,437E-03 0,02448703 ! chemoattractant activity GO:0042056 6 6 0,000 5,437E-03 0,02445684 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 5,437E-03 0,02442672 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 5,437E-03 0,02439667 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 5,437E-03 0,0243667 ! leukocyte degranulation GO:0043299 6 6 0,000 5,437E-03 0,0243368 ! bile acid and bile salt transport GO:0015721 7 6 0,000 5,437E-03 0,02430698 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 5,437E-03 0,02427723 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 5,437E-03 0,02424755 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 5,437E-03 0,02421794 ! DNA topoisomerase activity GO:0003916 6 6 0,000 5,437E-03 0,02418841 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 5,437E-03 0,02415895 ! ceramide biosynthetic process GO:0046513 6 6 0,000 5,437E-03 0,02412955 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 5,437E-03 0,02410024 ! activin receptor activity GO:0017002 7 6 0,000 5,437E-03 0,02407099 ! astrocyte differentiation GO:0048708 6 6 0,000 5,437E-03 0,02404181 ! syncytium formation GO:0006949 6 6 0,000 5,437E-03 0,0240127 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 5,437E-03 0,02398367 ! neutrophil activation GO:0042119 6 6 0,000 5,437E-03 0,0239547 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 5,437E-03 0,02392581 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 5,437E-03 0,02389698 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 5,437E-03 0,02386822 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 5,437E-03 0,02383954 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 5,437E-03 0,02381092 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 5,437E-03 0,02378237 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 5,437E-03 0,02375389 ! neuron apoptosis GO:0051402 7 6 0,000 5,437E-03 0,02372547 ! folic acid transport GO:0015884 8 6 0,000 5,437E-03 0,02369713 ! carnitine transport GO:0015879 6 6 0,000 5,437E-03 0,02366885 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 5,437E-03 0,02364064 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 5,437E-03 0,02361249 ! S-methyltransferase activity GO:0008172 6 6 0,000 5,437E-03 0,02358442 ! phospholipase D activity GO:0004630 6 6 0,000 5,437E-03 0,02355641 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 5,437E-03 0,02352846 ! intercalated disc GO:0014704 8 6 0,000 5,437E-03 0,02350059 ! G2/M transition checkpoint GO:0031576 24 6 0,000 5,437E-03 0,02347277 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 5,437E-03 0,02344503 ! IgG binding GO:0019864 6 6 0,000 5,437E-03 0,02341735 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 5,437E-03 0,02338973 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 5,437E-03 0,02336218 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 5,437E-03 0,0233347 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 5,437E-03 0,02330728 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 5,437E-03 0,02327992 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 5,437E-03 0,02325263 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 5,437E-03 0,0232254 ! dendrite morphogenesis GO:0048813 7 6 0,000 5,437E-03 0,02319824 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 5,437E-03 0,02317114 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 5,437E-03 0,0231441 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 5,437E-03 0,02311713 ! general transcriptional repressor activity GO:0016565 7 6 0,000 5,437E-03 0,02309021 ! regulation of mast cell activation GO:0033003 6 6 0,000 5,437E-03 0,02306337 ! tetracycline transporter activity GO:0008493 7 6 0,000 5,437E-03 0,02303658 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 5,437E-03 0,02300985 ! receptor internalization GO:0031623 8 6 0,000 5,437E-03 0,02298319 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 5,437E-03 0,02295659 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 5,437E-03 0,02293005 ! histamine receptor activity GO:0004969 7 6 0,000 5,437E-03 0,02290357 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 5,437E-03 0,02287716 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 5,437E-03 0,0228508 ! protein deubiquitination GO:0016579 6 6 0,000 5,437E-03 0,0228245 ! axonal fasciculation GO:0007413 7 6 0,000 5,437E-03 0,02279827 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 5,437E-03 0,02277209 ! cytidine deaminase activity GO:0004126 6 6 0,000 5,437E-03 0,02274598 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 5,437E-03 0,02271992 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 5,437E-03 0,02269393 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 5,437E-03 0,02266799 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 5,437E-03 0,02264212 ! glycine binding GO:0016594 9 6 0,000 5,437E-03 0,0226163 ! apical protein localization GO:0045176 7 6 0,000 5,437E-03 0,02259054 ! ankyrin binding GO:0030506 6 6 0,000 5,437E-03 0,02256484 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 5,437E-03 0,0225392 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 5,437E-03 0,02251361 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 5,437E-03 0,02248809 ! progesterone metabolic process GO:0042448 6 6 0,000 5,437E-03 0,02246262 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 5,437E-03 0,02243721 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 5,437E-03 0,02241186 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 5,437E-03 0,02238656 ! ATP catabolic process GO:0006200 6 6 0,000 5,437E-03 0,02236132 ! CoA carboxylase activity GO:0016421 6 6 0,000 5,437E-03 0,02233614 ! determination of adult lifespan GO:0008340 6 6 0,000 5,437E-03 0,02231102 ! S-acyltransferase activity GO:0016417 6 6 0,000 5,437E-03 0,02228595 ! somatic stem cell maintenance GO:0035019 6 6 0,000 5,437E-03 0,02226094 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 5,437E-03 0,02223598 ! IkappaB kinase complex GO:0008385 7 6 0,000 5,437E-03 0,02221108 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 5,437E-03 0,02218624 ! store-operated calcium channel activity GO:0015279 6 6 0,000 5,437E-03 0,02216145 ! alkaline phosphatase activity GO:0004035 7 6 0,000 5,437E-03 0,02213671 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 5,437E-03 0,02211203 ! unconventional myosin complex GO:0016461 8 6 0,000 5,437E-03 0,02208741 ! tRNA transcription GO:0009304 7 7 0,000 6,341E-03 0,02572899 ! respiratory burst GO:0045730 7 7 0,000 6,341E-03 0,0257004 ! telencephalon cell migration GO:0022029 8 7 0,000 6,341E-03 0,02567187 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 6,341E-03 0,02564341 ! cation:chloride symporter activity GO:0015377 8 7 0,000 6,341E-03 0,02561502 ! RNA cap binding GO:0000339 8 7 0,000 6,341E-03 0,02558668 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 6,341E-03 0,02555841 ! ephrin receptor binding GO:0046875 9 7 0,000 6,341E-03 0,0255302 ! male meiosis I GO:0007141 7 7 0,000 6,341E-03 0,02550205 ! synapsis GO:0007129 7 7 0,000 6,341E-03 0,02547396 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 6,341E-03 0,02544594 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 6,341E-03 0,02541798 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 6,341E-03 0,02539008 ! signal peptide processing GO:0006465 7 7 0,000 6,341E-03 0,02536224 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 6,341E-03 0,02533446 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 6,341E-03 0,02530674 ! macrophage chemotaxis GO:0048246 7 7 0,000 6,341E-03 0,02527908 ! Golgi cisterna membrane GO:0032580 7 7 0,000 6,341E-03 0,02525148 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 6,341E-03 0,02522395 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 6,341E-03 0,02519647 ! smoothened signaling pathway GO:0007224 8 7 0,000 6,341E-03 0,02516905 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 6,341E-03 0,02514169 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 6,341E-03 0,0251144 ! cytoplasmic microtubule GO:0005881 7 7 0,000 6,341E-03 0,02508716 ! Arp2/3 protein complex GO:0005885 8 7 0,000 6,341E-03 0,02505998 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 6,341E-03 0,02503286 ! ATPase binding GO:0051117 8 7 0,000 6,341E-03 0,02500579 ! positive regulation of isotype switching GO:0045830 7 7 0,000 6,341E-03 0,02497879 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 6,341E-03 0,02495184 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 6,341E-03 0,02492496 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,341E-03 0,02489813 ! thymic T cell selection GO:0045061 16 7 0,000 6,341E-03 0,02487135 ! transepithelial chloride transport GO:0030321 7 7 0,000 6,341E-03 0,02484464 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 6,341E-03 0,02481798 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 6,341E-03 0,02479138 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 6,341E-03 0,02476484 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 6,341E-03 0,02473835 ! melanocyte differentiation GO:0030318 8 7 0,000 6,341E-03 0,02471192 ! malate dehydrogenase activity GO:0016615 8 7 0,000 6,341E-03 0,02468555 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 6,341E-03 0,02465923 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 6,341E-03 0,02463297 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 6,341E-03 0,02460676 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 6,341E-03 0,02458062 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 6,341E-03 0,02455452 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 6,341E-03 0,02452848 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 6,341E-03 0,0245025 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 6,341E-03 0,02447657 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 6,341E-03 0,0244507 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 6,341E-03 0,02442488 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 6,341E-03 0,02439911 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 6,341E-03 0,0243734 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 6,341E-03 0,02434775 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 6,341E-03 0,02432214 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 6,341E-03 0,0242966 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 6,341E-03 0,0242711 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 6,341E-03 0,02424566 ! melanosome organization GO:0032438 7 7 0,000 6,341E-03 0,02422027 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 6,341E-03 0,02419494 ! mesodermal cell differentiation GO:0048333 9 7 0,000 6,341E-03 0,02416965 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 6,341E-03 0,02414442 ! Rac protein signal transduction GO:0016601 7 7 0,000 6,341E-03 0,02411925 ! chondrocyte differentiation GO:0002062 7 7 0,000 6,341E-03 0,02409412 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 6,341E-03 0,02406905 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 6,341E-03 0,02404403 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 6,341E-03 0,02401906 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 6,341E-03 0,02399415 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 6,341E-03 0,02396928 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 6,341E-03 0,02394447 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 6,341E-03 0,02391971 ! Schwann cell differentiation GO:0014037 8 7 0,000 6,341E-03 0,023895 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 6,341E-03 0,02387034 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 6,341E-03 0,02384573 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 6,341E-03 0,02382117 ! vinculin binding GO:0017166 9 7 0,000 6,341E-03 0,02379667 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 6,341E-03 0,02377221 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 6,341E-03 0,0237478 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 6,341E-03 0,02372345 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 6,341E-03 0,02369914 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 6,341E-03 0,02367488 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 6,341E-03 0,02365067 ! cardiac muscle cell development GO:0055013 8 7 0,000 6,341E-03 0,02362652 ! fibrinolysis GO:0042730 9 7 0,000 6,341E-03 0,02360241 ! response to tropane GO:0014073 10 7 0,000 6,341E-03 0,02357835 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 6,341E-03 0,02355434 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 6,341E-03 0,02353038 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 6,341E-03 0,02350646 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 6,341E-03 0,0234826 ! laminin-1 complex GO:0005606 7 7 0,000 6,341E-03 0,02345878 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 6,341E-03 0,02343501 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 6,341E-03 0,02341129 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 6,341E-03 0,02338762 ! regulation of cell division GO:0051302 7 7 0,000 6,341E-03 0,023364 ! holo TFIIH complex GO:0005675 7 7 0,000 6,341E-03 0,02334042 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 6,341E-03 0,02331689 ! chitinase activity GO:0004568 7 7 0,000 6,341E-03 0,02329341 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 6,341E-03 0,02326998 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 6,341E-03 0,02324659 ! regulation of respiratory burst GO:0060263 8 7 0,000 6,341E-03 0,02322325 ! prophase GO:0051324 8 7 0,000 6,341E-03 0,02319996 ! peptidyl-histidine modification GO:0018202 8 7 0,000 6,341E-03 0,02317671 ! centriolar satellite GO:0034451 10 7 0,000 6,341E-03 0,02315351 ! BBSome GO:0034464 7 7 0,000 6,341E-03 0,02313036 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 6,341E-03 0,02310725 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,341E-03 0,02308419 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 6,341E-03 0,02306118 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 6,341E-03 0,02303821 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 6,341E-03 0,02301528 ! regulation of synaptogenesis GO:0051963 7 7 0,000 6,341E-03 0,0229924 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 6,341E-03 0,02296957 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 6,341E-03 0,02294678 ! glycolipid catabolic process GO:0019377 7 7 0,000 6,341E-03 0,02292404 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 6,341E-03 0,02290135 ! circadian behavior GO:0048512 9 7 0,000 6,341E-03 0,02287869 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 6,341E-03 0,02285609 ! striatum development GO:0021756 7 7 0,000 6,341E-03 0,02283352 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 6,341E-03 0,022811 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 6,341E-03 0,02278853 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 6,341E-03 0,0227661 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 6,341E-03 0,02274372 ! dystroglycan complex GO:0016011 9 7 0,000 6,341E-03 0,02272137 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 6,341E-03 0,02269908 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 6,341E-03 0,02267682 ! peroxiredoxin activity GO:0051920 7 7 0,000 6,341E-03 0,02265461 ! muscle adaptation GO:0043500 7 7 0,000 6,341E-03 0,02263245 ! regulation of muscle adaptation GO:0043502 7 7 0,000 6,341E-03 0,02261032 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 6,341E-03 0,02258824 ! protein insertion into membrane GO:0051205 7 7 0,000 6,341E-03 0,0225662 ! sequestering of metal ion GO:0051238 9 7 0,000 6,341E-03 0,02254421 ! membrane attack complex GO:0005579 7 7 0,000 6,341E-03 0,02252226 ! fibrinogen complex GO:0005577 7 7 0,000 6,341E-03 0,02250035 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 6,341E-03 0,02247848 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 6,341E-03 0,02245666 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 6,341E-03 0,02243488 ! GABA receptor binding GO:0050811 8 7 0,000 6,341E-03 0,02241314 ! sheet-forming collagen GO:0030935 7 7 0,000 6,341E-03 0,02239144 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 6,341E-03 0,02236979 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 6,341E-03 0,02234817 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 6,341E-03 0,0223266 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 6,341E-03 0,02230507 ! 7S RNA binding GO:0008312 8 7 0,000 6,341E-03 0,02228358 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 6,341E-03 0,02226214 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 6,341E-03 0,02224073 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 6,341E-03 0,02221936 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 6,341E-03 0,02219804 ! Golgi to endosome transport GO:0006895 8 7 0,000 6,341E-03 0,02217676 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 6,341E-03 0,02215552 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 6,341E-03 0,02213431 ! fibril GO:0043205 7 7 0,000 6,341E-03 0,02211315 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,341E-03 0,02209203 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 6,341E-03 0,02207095 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 6,341E-03 0,02204991 ! sensory perception of bitter taste GO:0050913 7 7 0,000 6,341E-03 0,02202891 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 6,341E-03 0,02200795 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 6,341E-03 0,02198703 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 6,341E-03 0,02196615 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 6,341E-03 0,02194531 ! equilibrioception GO:0050957 10 7 0,000 6,341E-03 0,02192451 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 6,341E-03 0,02190375 ! titin binding GO:0031432 7 7 0,000 6,341E-03 0,02188303 ! chemosensory behavior GO:0007635 9 7 0,000 6,341E-03 0,02186234 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 6,341E-03 0,0218417 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 6,341E-03 0,02182109 ! cobalamin binding GO:0031419 7 7 0,000 6,341E-03 0,02180053 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 6,341E-03 0,02178 ! response to axon injury GO:0048678 9 7 0,000 6,341E-03 0,02175951 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 6,341E-03 0,02173906 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 6,341E-03 0,02171865 ! F-actin capping protein complex GO:0008290 8 7 0,000 6,341E-03 0,02169827 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 6,341E-03 0,02167794 ! cGMP-mediated signaling GO:0019934 8 7 0,000 6,341E-03 0,02165764 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 6,341E-03 0,02163738 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 6,341E-03 0,02161716 ! senescence GO:0010149 8 7 0,000 6,341E-03 0,02159697 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 6,341E-03 0,02157683 ! nuclear localization sequence binding GO:0008139 8 7 0,000 6,341E-03 0,02155672 ! galactose metabolic process GO:0006012 8 7 0,000 6,341E-03 0,02153665 ! vesicle fusion GO:0006906 8 7 0,000 6,341E-03 0,02151661 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 6,341E-03 0,02149662 ! intracellular pH reduction GO:0051452 7 7 0,000 6,341E-03 0,02147666 ! glycerol ether catabolic process GO:0044269 16 7 0,000 6,341E-03 0,02145673 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 6,341E-03 0,02143685 ! ruffle organization GO:0031529 9 7 0,000 6,341E-03 0,021417 ! nucleoside transport GO:0015858 8 7 0,000 6,341E-03 0,02139719 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 6,341E-03 0,02137741 ! inclusion body GO:0016234 7 7 0,000 6,341E-03 0,02135767 ! Cajal body GO:0015030 7 7 0,000 6,341E-03 0,02133797 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 6,341E-03 0,0213183 ! rRNA modification GO:0000154 7 7 0,000 6,341E-03 0,02129867 ! PcG protein complex GO:0031519 7 7 0,000 6,341E-03 0,02127908 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 6,341E-03 0,02125952 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 6,341E-03 0,02124 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 6,341E-03 0,02122051 ! apolipoprotein binding GO:0034185 9 7 0,000 6,341E-03 0,02120106 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 6,341E-03 0,02118165 ! segment specification GO:0007379 9 7 0,000 6,341E-03 0,02116227 ! pronucleus GO:0045120 25 7 0,000 6,341E-03 0,02114292 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 6,341E-03 0,02112362 ! Rac GTPase activator activity GO:0030675 9 7 0,000 6,341E-03 0,02110434 ! regulation of DNA repair GO:0006282 19 7 0,000 6,341E-03 0,0210851 ! preribosome GO:0030684 7 7 0,000 6,341E-03 0,0210659 ! DNA topological change GO:0006265 7 7 0,000 6,341E-03 0,02104673 ! DNA ligation GO:0006266 8 7 0,000 6,341E-03 0,0210276 ! hair follicle maturation GO:0048820 8 7 0,000 6,341E-03 0,0210085 ! renal water homeostasis GO:0003091 7 7 0,000 6,341E-03 0,02098944 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 6,341E-03 0,02097041 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 6,341E-03 0,02095141 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 6,341E-03 0,02093245 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 6,341E-03 0,02091353 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 6,341E-03 0,02089463 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 6,341E-03 0,02087578 ! phosphofructokinase activity GO:0008443 7 7 0,000 6,341E-03 0,02085695 ! gap junction channel activity GO:0005243 8 7 0,000 6,341E-03 0,02083816 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 6,341E-03 0,0208194 ! histone methylation GO:0016571 7 7 0,000 6,341E-03 0,02080068 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 6,341E-03 0,02078199 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 6,341E-03 0,02076334 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 6,341E-03 0,02074472 ! muscle cell proliferation GO:0033002 8 7 0,000 6,341E-03 0,02072613 ! transcription termination GO:0006353 9 7 0,000 6,341E-03 0,02070757 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 6,341E-03 0,02068905 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 6,341E-03 0,02067056 ! cytidylyltransferase activity GO:0070567 8 7 0,000 6,341E-03 0,02065211 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 6,341E-03 0,02063368 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 6,341E-03 0,02061529 ! salivary gland development GO:0007431 7 7 0,000 6,341E-03 0,02059694 ! glucosidase activity GO:0015926 8 7 0,000 6,341E-03 0,02057861 ! NuRD complex GO:0016581 8 7 0,000 6,341E-03 0,02056032 ! negative regulation of nuclear division GO:0051784 7 7 0,000 6,341E-03 0,02054206 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 6,341E-03 0,02052383 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 6,341E-03 0,02050564 ! response to redox state GO:0051775 8 7 0,000 6,341E-03 0,02048747 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 6,341E-03 0,02046934 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 6,341E-03 0,02045125 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 6,341E-03 0,02043318 ! actin monomer binding GO:0003785 7 7 0,000 6,341E-03 0,02041514 ! protein prenyltransferase activity GO:0008318 8 7 0,000 6,341E-03 0,02039714 ! endosome to lysosome transport GO:0008333 7 7 0,000 6,341E-03 0,02037917 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 6,341E-03 0,02036123 ! germ cell migration GO:0008354 7 7 0,000 6,341E-03 0,02034332 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 6,341E-03 0,02032545 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 6,341E-03 0,0203076 ! CoA-ligase activity GO:0016405 8 7 0,000 6,341E-03 0,02028979 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 6,341E-03 0,02027201 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 6,341E-03 0,02025425 ! embryonic heart tube development GO:0035050 8 7 0,000 6,341E-03 0,02023653 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 6,341E-03 0,02021885 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 6,341E-03 0,02020119 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 6,341E-03 0,02018356 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 6,341E-03 0,02016596 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 6,341E-03 0,0201484 ! adenylate kinase activity GO:0004017 8 7 0,000 6,341E-03 0,02013086 ! negative regulation of immune effector process GO:0002698 13 7 0,000 6,341E-03 0,02011336 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 6,341E-03 0,02009588 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 6,341E-03 0,02007844 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 7,243E-03 0,02291709 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 7,243E-03 0,02289723 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 7,243E-03 0,02287741 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 7,243E-03 0,02285762 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 7,243E-03 0,02283786 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 7,243E-03 0,02281814 ! proteasome regulatory particle GO:0005838 8 8 0,000 7,243E-03 0,02279845 ! SMAD protein complex assembly GO:0007183 10 8 0,000 7,243E-03 0,0227788 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 7,243E-03 0,02275918 ! protein self-association GO:0043621 8 8 0,000 7,243E-03 0,02273959 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 7,243E-03 0,02272004 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 7,243E-03 0,02270052 ! neurotransmitter uptake GO:0001504 8 8 0,000 7,243E-03 0,02268103 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 7,243E-03 0,02266158 ! guanylate cyclase activity GO:0004383 9 8 0,000 7,243E-03 0,02264216 ! troponin complex GO:0005861 8 8 0,000 7,243E-03 0,02262278 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 7,243E-03 0,02260343 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 7,243E-03 0,02258411 ! keratinocyte proliferation GO:0043616 9 8 0,000 7,243E-03 0,02256482 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 7,243E-03 0,02254557 ! microtubule bundle formation GO:0001578 8 8 0,000 7,243E-03 0,02252635 ! middle ear morphogenesis GO:0042474 10 8 0,000 7,243E-03 0,02250716 ! ganglioside metabolic process GO:0001573 8 8 0,000 7,243E-03 0,022488 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 7,243E-03 0,02246888 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 7,243E-03 0,02244979 ! ciliary or flagellar motility GO:0001539 8 8 0,000 7,243E-03 0,02243073 ! pathogenesis GO:0009405 8 8 0,000 7,243E-03 0,02241171 ! pH reduction GO:0045851 9 8 0,000 7,243E-03 0,02239272 ! small protein activating enzyme activity GO:0008641 10 8 0,000 7,243E-03 0,02237376 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 7,243E-03 0,02235483 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 7,243E-03 0,02233593 ! hemoglobin metabolic process GO:0020027 8 8 0,000 7,243E-03 0,02231707 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 7,243E-03 0,02229823 ! arginine catabolic process GO:0006527 9 8 0,000 7,243E-03 0,02227943 ! T-tubule GO:0030315 9 8 0,000 7,243E-03 0,02226066 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 7,243E-03 0,02224192 ! histidine catabolic process GO:0006548 8 8 0,000 7,243E-03 0,02222322 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 7,243E-03 0,02220454 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 7,243E-03 0,0221859 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 7,243E-03 0,02216729 ! proline metabolic process GO:0006560 10 8 0,000 7,243E-03 0,02214871 ! L-serine metabolic process GO:0006563 9 8 0,000 7,243E-03 0,02213016 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 7,243E-03 0,02211164 ! melanosome membrane GO:0033162 9 8 0,000 7,243E-03 0,02209315 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 7,243E-03 0,02207469 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 7,243E-03 0,02205627 ! pericentriolar material GO:0000242 9 8 0,000 7,243E-03 0,02203787 ! reverse cholesterol transport GO:0043691 8 8 0,000 7,243E-03 0,0220195 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 7,243E-03 0,02200117 ! melanin metabolic process GO:0006582 10 8 0,000 7,243E-03 0,02198287 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 7,243E-03 0,02196459 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 7,243E-03 0,02194635 ! Golgi lumen GO:0005796 8 8 0,000 7,243E-03 0,02192814 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 7,243E-03 0,02190995 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 7,243E-03 0,0218918 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 7,243E-03 0,02187368 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 7,243E-03 0,02185559 ! stereocilium bundle GO:0032421 11 8 0,000 7,243E-03 0,02183753 ! forebrain cell migration GO:0021885 9 8 0,000 7,243E-03 0,02181949 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 7,243E-03 0,02180149 ! osteoblast development GO:0002076 11 8 0,000 7,243E-03 0,02178352 ! retinoic acid metabolic process GO:0042573 8 8 0,000 7,243E-03 0,02176557 ! retinol metabolic process GO:0042572 8 8 0,000 7,243E-03 0,02174766 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 7,243E-03 0,02172977 ! structural constituent of epidermis GO:0030280 9 8 0,000 7,243E-03 0,02171192 ! clathrin binding GO:0030276 10 8 0,000 7,243E-03 0,02169409 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 7,243E-03 0,0216763 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 7,243E-03 0,02165853 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 7,243E-03 0,02164079 ! motor axon guidance GO:0008045 8 8 0,000 7,243E-03 0,02162308 ! protein targeting to vacuole GO:0006623 8 8 0,000 7,243E-03 0,0216054 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 7,243E-03 0,02158775 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 7,243E-03 0,02157013 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 7,243E-03 0,02155253 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 7,243E-03 0,02153497 ! protein-lipid complex assembly GO:0065005 8 8 0,000 7,243E-03 0,02151743 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 7,243E-03 0,02149992 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 7,243E-03 0,02148244 ! regulation of dopamine secretion GO:0014059 9 8 0,000 7,243E-03 0,02146499 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 7,243E-03 0,02144757 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 7,243E-03 0,02143017 ! subpallium development GO:0021544 8 8 0,000 7,243E-03 0,02141281 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 7,243E-03 0,02139547 ! icosanoid secretion GO:0032309 10 8 0,000 7,243E-03 0,02137816 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 7,243E-03 0,02136088 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 7,243E-03 0,02134362 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 7,243E-03 0,0213264 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 7,243E-03 0,0213092 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 7,243E-03 0,02129203 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 7,243E-03 0,02127488 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 7,243E-03 0,02125777 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 7,243E-03 0,02124068 ! ubiquinone metabolic process GO:0006743 9 8 0,000 7,243E-03 0,02122362 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 7,243E-03 0,02120659 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 7,243E-03 0,02118958 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 7,243E-03 0,0211726 ! Wnt receptor activity GO:0042813 11 8 0,000 7,243E-03 0,02115565 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 7,243E-03 0,02113872 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 7,243E-03 0,02112183 ! detection of calcium ion GO:0005513 9 8 0,000 7,243E-03 0,02110496 ! negative regulation of glucose import GO:0046325 9 8 0,000 7,243E-03 0,02108811 ! blastocyst growth GO:0001832 8 8 0,000 7,243E-03 0,0210713 ! regulation of fibrinolysis GO:0051917 8 8 0,000 7,243E-03 0,02105451 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 7,243E-03 0,02103774 ! cerebellar cortex formation GO:0021697 9 8 0,000 7,243E-03 0,02102101 ! complement binding GO:0001848 11 8 0,000 7,243E-03 0,0210043 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 7,243E-03 0,02098761 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 7,243E-03 0,02097096 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 7,243E-03 0,02095433 ! amino sugar catabolic process GO:0046348 8 8 0,000 7,243E-03 0,02093772 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 7,243E-03 0,02092114 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 7,243E-03 0,02090459 ! positive regulation of amine transport GO:0051954 9 8 0,000 7,243E-03 0,02088807 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 7,243E-03 0,02087157 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 7,243E-03 0,0208551 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,243E-03 0,02083865 ! Golgi transport complex GO:0017119 8 8 0,000 7,243E-03 0,02082223 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 7,243E-03 0,02080583 ! GDP binding GO:0019003 9 8 0,000 7,243E-03 0,02078946 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 7,243E-03 0,02077312 ! prostate gland development GO:0030850 17 8 0,000 7,243E-03 0,0207568 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 7,243E-03 0,02074051 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 7,243E-03 0,02072424 ! phosphate transport GO:0006817 9 8 0,000 7,243E-03 0,020708 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 7,243E-03 0,02069178 ! oligopeptide transport GO:0006857 8 8 0,000 7,243E-03 0,02067559 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 7,243E-03 0,02065943 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 7,243E-03 0,02064329 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 7,243E-03 0,02062717 ! lipoprotein transport GO:0042953 9 8 0,000 7,243E-03 0,02061108 ! estrogen metabolic process GO:0008210 8 8 0,000 7,243E-03 0,02059502 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 7,243E-03 0,02057898 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 7,243E-03 0,02056296 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 7,243E-03 0,02054697 ! T-helper 1 type immune response GO:0042088 8 8 0,000 7,243E-03 0,02053101 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 7,243E-03 0,02051507 ! response to amphetamine GO:0001975 11 8 0,000 7,243E-03 0,02049915 ! mechanosensory behavior GO:0007638 8 8 0,000 7,243E-03 0,02048326 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 7,243E-03 0,02046739 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 7,243E-03 0,02045155 ! C-X-C chemokine binding GO:0019958 8 8 0,000 7,243E-03 0,02043574 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 7,243E-03 0,02041994 ! glycerolipid catabolic process GO:0046503 17 8 0,000 7,243E-03 0,02040417 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 7,243E-03 0,02038843 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 7,243E-03 0,02037271 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 7,243E-03 0,02035702 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 7,243E-03 0,02034134 ! pigment granule organization GO:0048753 9 8 0,000 7,243E-03 0,0203257 ! GTP-dependent protein binding GO:0030742 11 8 0,000 7,243E-03 0,02031007 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 7,243E-03 0,02029447 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 7,243E-03 0,0202789 ! regulation of pigmentation during development GO:0048070 11 8 0,000 7,243E-03 0,02026335 ! macrophage activation GO:0042116 8 8 0,000 7,243E-03 0,02024782 ! poly(A) RNA binding GO:0008143 8 8 0,000 7,243E-03 0,02023232 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 7,243E-03 0,02021684 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 7,243E-03 0,02020138 ! asymmetric protein localization GO:0008105 9 8 0,000 7,243E-03 0,02018595 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 7,243E-03 0,02017054 ! neurotrophin binding GO:0043121 10 8 0,000 7,243E-03 0,02015515 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 7,243E-03 0,02013979 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 7,243E-03 0,02012445 ! phagocytosis, engulfment GO:0006911 10 8 0,000 7,243E-03 0,02010914 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 7,243E-03 0,02009384 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 7,243E-03 0,02007858 ! UV protection GO:0009650 9 8 0,000 7,243E-03 0,02006333 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 7,243E-03 0,02004811 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 7,243E-03 0,02003291 ! glutathione peroxidase activity GO:0004602 17 8 0,000 7,243E-03 0,02001773 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 7,243E-03 0,02000258 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 7,243E-03 0,01998745 ! ferric iron binding GO:0008199 9 8 0,000 7,243E-03 0,01997234 ! response to UV-B GO:0010224 10 8 0,000 7,243E-03 0,01995726 ! intermediate filament organization GO:0045109 8 8 0,000 7,243E-03 0,01994219 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 7,243E-03 0,01992715 ! cellular extravasation GO:0045123 9 8 0,000 7,243E-03 0,01991214 ! skeletal muscle contraction GO:0003009 8 8 0,000 7,243E-03 0,01989714 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 7,243E-03 0,01988217 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 7,243E-03 0,01986722 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 7,243E-03 0,0198523 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 7,243E-03 0,01983739 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 7,243E-03 0,01982251 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 7,243E-03 0,01980765 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 7,243E-03 0,01979281 ! erythrocyte development GO:0048821 9 8 0,000 7,243E-03 0,019778 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 7,243E-03 0,01976321 ! ribosome assembly GO:0042255 8 8 0,000 7,243E-03 0,01974843 ! postreplication repair GO:0006301 19 8 0,000 7,243E-03 0,01973369 ! gamma-tubulin binding GO:0043015 8 8 0,000 7,243E-03 0,01971896 ! NADPH oxidase complex GO:0043020 8 8 0,000 7,243E-03 0,01970425 ! mRNA cleavage GO:0006379 9 8 0,000 7,243E-03 0,01968957 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 7,243E-03 0,01967491 ! opioid receptor activity GO:0004985 8 8 0,000 7,243E-03 0,01966027 ! zymogen activation GO:0031638 9 8 0,000 7,243E-03 0,01964565 ! coenzyme A metabolic process GO:0015936 8 8 0,000 7,243E-03 0,01963106 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 7,243E-03 0,01961649 ! costamere GO:0043034 8 8 0,000 7,243E-03 0,01960193 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 7,243E-03 0,0195874 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 7,243E-03 0,01957289 ! sarcomere organization GO:0045214 9 8 0,000 7,243E-03 0,01955841 ! wide pore channel activity GO:0022829 9 8 0,000 7,243E-03 0,01954394 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 7,243E-03 0,01952949 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 7,243E-03 0,01951507 ! hormone catabolic process GO:0042447 9 8 0,000 7,243E-03 0,01950067 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 7,243E-03 0,01948629 ! cGMP biosynthetic process GO:0006182 9 8 0,000 7,243E-03 0,01947193 ! lysozyme activity GO:0003796 10 8 0,000 7,243E-03 0,01945759 ! death receptor binding GO:0005123 8 8 0,000 7,243E-03 0,01944327 ! protein modification by small protein removal GO:0070646 9 8 0,000 7,243E-03 0,01942897 ! adult feeding behavior GO:0008343 9 8 0,000 7,243E-03 0,0194147 ! microtubule basal body GO:0005932 8 8 0,000 7,243E-03 0,01940044 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 7,243E-03 0,01938621 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 7,243E-03 0,019372 ! calcium-release channel activity GO:0015278 8 8 0,000 7,243E-03 0,01935781 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 7,243E-03 0,01934364 ! behavioral response to nicotine GO:0035095 9 8 0,000 7,243E-03 0,01932948 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 7,243E-03 0,01931536 ! adenosine deaminase activity GO:0004000 8 8 0,000 7,243E-03 0,01930125 ! NAD biosynthetic process GO:0009435 9 8 0,000 7,243E-03 0,01928716 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 8,145E-03 0,02167297 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 8,145E-03 0,02165717 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 8,145E-03 0,0216414 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 8,145E-03 0,02162565 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 8,145E-03 0,02160992 ! myotube differentiation GO:0014902 9 9 0,000 8,145E-03 0,02159421 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 8,145E-03 0,02157853 ! N-glycan processing GO:0006491 10 9 0,000 8,145E-03 0,02156287 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 8,145E-03 0,02154723 ! actin-myosin filament sliding GO:0033275 11 9 0,000 8,145E-03 0,02153162 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 8,145E-03 0,02151603 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 8,145E-03 0,02150046 ! RNA methylation GO:0001510 9 9 0,000 8,145E-03 0,02148491 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 8,145E-03 0,02146939 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 8,145E-03 0,02145389 ! artery development GO:0060840 9 9 0,000 8,145E-03 0,02143841 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 8,145E-03 0,02142295 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 8,145E-03 0,02140752 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 8,145E-03 0,02139211 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 8,145E-03 0,02137672 ! positive regulation of heart contraction GO:0045823 11 9 0,000 8,145E-03 0,02136135 ! lipopolysaccharide binding GO:0001530 9 9 0,000 8,145E-03 0,021346 ! regulated secretory pathway GO:0045055 10 9 0,000 8,145E-03 0,02133068 ! estrogen receptor binding GO:0030331 9 9 0,000 8,145E-03 0,02131538 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 8,145E-03 0,0213001 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 8,145E-03 0,02128484 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 8,145E-03 0,0212696 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 8,145E-03 0,02125439 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 8,145E-03 0,0212392 ! urea metabolic process GO:0019627 19 9 0,000 8,145E-03 0,02122403 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 8,145E-03 0,02120888 ! autophagic vacuole GO:0005776 11 9 0,000 8,145E-03 0,02119375 ! Rac GTPase binding GO:0048365 10 9 0,000 8,145E-03 0,02117864 ! response to dietary excess GO:0002021 9 9 0,000 8,145E-03 0,02116356 ! regulation of sodium ion transport GO:0002028 10 9 0,000 8,145E-03 0,0211485 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 8,145E-03 0,02113345 ! lens development in camera-type eye GO:0002088 9 9 0,000 8,145E-03 0,02111843 ! male sex determination GO:0030238 9 9 0,000 8,145E-03 0,02110344 ! positive regulation of vasodilation GO:0045909 19 9 0,000 8,145E-03 0,02108846 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 8,145E-03 0,0210735 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 8,145E-03 0,02105857 ! male germ cell nucleus GO:0001673 11 9 0,000 8,145E-03 0,02104365 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 8,145E-03 0,02102876 ! copper ion homeostasis GO:0055070 9 9 0,000 8,145E-03 0,02101389 ! protein heterooligomerization GO:0051291 10 9 0,000 8,145E-03 0,02099904 ! spectrin GO:0008091 9 9 0,000 8,145E-03 0,02098421 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 8,145E-03 0,0209694 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 8,145E-03 0,02095461 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 8,145E-03 0,02093984 ! regulation of B cell differentiation GO:0045577 10 9 0,000 8,145E-03 0,0209251 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 8,145E-03 0,02091037 ! neural tube patterning GO:0021532 10 9 0,000 8,145E-03 0,02089567 ! fucose catabolic process GO:0019317 10 9 0,000 8,145E-03 0,02088098 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 8,145E-03 0,02086632 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 8,145E-03 0,02085167 ! sterol catabolic process GO:0016127 10 9 0,000 8,145E-03 0,02083705 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 8,145E-03 0,02082245 ! clathrin coat of coated pit GO:0030132 11 9 0,000 8,145E-03 0,02080787 ! SNARE complex GO:0031201 11 9 0,000 8,145E-03 0,02079331 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 8,145E-03 0,02077877 ! negative regulation of glucose transport GO:0010829 10 9 0,000 8,145E-03 0,02076425 ! methionine biosynthetic process GO:0009086 11 9 0,000 8,145E-03 0,02074975 ! peptidoglycan binding GO:0042834 9 9 0,000 8,145E-03 0,02073527 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 8,145E-03 0,02072081 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 8,145E-03 0,02070637 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 8,145E-03 0,02069195 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 8,145E-03 0,02067755 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 8,145E-03 0,02066317 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 8,145E-03 0,02064881 ! detection of bacterium GO:0016045 10 9 0,000 8,145E-03 0,02063447 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 8,145E-03 0,02062015 ! embryonic gut development GO:0048566 10 9 0,000 8,145E-03 0,02060585 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 8,145E-03 0,02059157 ! desmosome GO:0030057 10 9 0,000 8,145E-03 0,02057731 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 8,145E-03 0,02056307 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 8,145E-03 0,02054885 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 8,145E-03 0,02053465 ! actin filament polymerization GO:0030041 10 9 0,000 8,145E-03 0,02052047 ! negative regulation of B cell activation GO:0050869 10 9 0,000 8,145E-03 0,02050631 ! establishment of cell polarity GO:0030010 10 9 0,000 8,145E-03 0,02049216 ! regulation of synapse organization GO:0050807 10 9 0,000 8,145E-03 0,02047804 ! septin complex GO:0031105 10 9 0,000 8,145E-03 0,02046394 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 8,145E-03 0,02044985 ! anchoring collagen GO:0030934 9 9 0,000 8,145E-03 0,02043579 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 8,145E-03 0,02042174 ! regulation of developmental growth GO:0048638 11 9 0,000 8,145E-03 0,02040772 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 8,145E-03 0,02039371 ! GMP binding GO:0019002 11 9 0,000 8,145E-03 0,02037972 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 8,145E-03 0,02036576 ! virus-host interaction GO:0019048 13 9 0,000 8,145E-03 0,02035181 ! pentose-phosphate shunt GO:0006098 11 9 0,000 8,145E-03 0,02033788 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 8,145E-03 0,02032396 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 8,145E-03 0,02031007 ! non-recombinational repair GO:0000726 10 9 0,000 8,145E-03 0,0202962 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 8,145E-03 0,02028235 ! nuclear telomere cap complex GO:0000783 10 9 0,000 8,145E-03 0,02026851 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 8,145E-03 0,02025469 ! social behavior GO:0035176 10 9 0,000 8,145E-03 0,0202409 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 8,145E-03 0,02022712 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 8,145E-03 0,02021336 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 8,145E-03 0,02019962 ! mating GO:0007618 11 9 0,000 8,145E-03 0,02018589 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 8,145E-03 0,02017219 ! rhythmic behavior GO:0007622 11 9 0,000 8,145E-03 0,02015851 ! phospholipid efflux GO:0033700 10 9 0,000 8,145E-03 0,02014484 ! poly-purine tract binding GO:0070717 9 9 0,000 8,145E-03 0,02013119 ! T cell proliferation GO:0042098 10 9 0,000 8,145E-03 0,02011756 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 8,145E-03 0,02010395 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 8,145E-03 0,02009036 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 8,145E-03 0,02007678 ! interleukin-1 binding GO:0019966 10 9 0,000 8,145E-03 0,02006323 ! glucosyltransferase activity GO:0046527 9 9 0,000 8,145E-03 0,02004969 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 8,145E-03 0,02003617 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 8,145E-03 0,02002267 ! ovulation GO:0030728 9 9 0,000 8,145E-03 0,02000918 ! acid phosphatase activity GO:0003993 18 9 0,000 8,145E-03 0,01999572 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 8,145E-03 0,01998227 ! ER overload response GO:0006983 11 9 0,000 8,145E-03 0,01996884 ! B cell proliferation GO:0042100 10 9 0,000 8,145E-03 0,01995543 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 8,145E-03 0,01994204 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 8,145E-03 0,01992866 ! mannose metabolic process GO:0006013 13 9 0,000 8,145E-03 0,01991531 ! lipid digestion GO:0044241 11 9 0,000 8,145E-03 0,01990197 ! tumor necrosis factor binding GO:0043120 9 9 0,000 8,145E-03 0,01988865 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 8,145E-03 0,01987534 ! regulation of bone resorption GO:0045124 10 9 0,000 8,145E-03 0,01986206 ! brain morphogenesis GO:0048854 9 9 0,000 8,145E-03 0,01984879 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 8,145E-03 0,01983554 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 8,145E-03 0,01982231 ! synaptic vesicle membrane GO:0030672 9 9 0,000 8,145E-03 0,01980909 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 8,145E-03 0,01979589 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 8,145E-03 0,01978271 ! kinesin binding GO:0019894 9 9 0,000 8,145E-03 0,01976955 ! multicellular organismal aging GO:0010259 18 9 0,000 8,145E-03 0,01975641 ! Ran GTPase binding GO:0008536 11 9 0,000 8,145E-03 0,01974328 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 8,145E-03 0,01973017 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 8,145E-03 0,01971708 ! mRNA polyadenylation GO:0006378 10 9 0,000 8,145E-03 0,019704 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 8,145E-03 0,01969095 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 8,145E-03 0,01967791 ! prostaglandin receptor activity GO:0004955 11 9 0,000 8,145E-03 0,01966488 ! caspase inhibitor activity GO:0043027 9 9 0,000 8,145E-03 0,01965188 ! adrenoceptor activity GO:0004935 12 9 0,000 8,145E-03 0,01963889 ! regulation of isotype switching GO:0045191 9 9 0,000 8,145E-03 0,01962592 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 8,145E-03 0,01961296 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 8,145E-03 0,01960002 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 8,145E-03 0,0195871 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 8,145E-03 0,0195742 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 8,145E-03 0,01956131 ! Notch binding GO:0005112 10 9 0,000 8,145E-03 0,01954845 ! ATPase regulator activity GO:0060590 10 9 0,000 8,145E-03 0,01953559 ! gamma-tubulin complex GO:0000930 19 9 0,000 8,145E-03 0,01952276 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 8,145E-03 0,01950994 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 8,145E-03 0,01949714 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 8,145E-03 0,01948435 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 8,145E-03 0,01947158 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 9,046E-03 0,02161169 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 9,046E-03 0,02159755 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 9,046E-03 0,02158342 ! sleep GO:0030431 11 10 0,000 9,046E-03 0,02156932 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 9,046E-03 0,02155523 ! lipid particle GO:0005811 10 10 0,000 9,046E-03 0,02154116 ! filopodium assembly GO:0046847 14 10 0,000 9,046E-03 0,02152711 ! UTP metabolic process GO:0046051 12 10 0,000 9,046E-03 0,02151307 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 9,046E-03 0,02149906 ! guanylate kinase activity GO:0004385 14 10 0,000 9,046E-03 0,02148506 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 9,046E-03 0,02147108 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 9,046E-03 0,02145712 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 9,046E-03 0,02144318 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 9,046E-03 0,02142926 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 9,046E-03 0,02141535 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 9,046E-03 0,02140146 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 9,046E-03 0,02138759 ! lung alveolus development GO:0048286 11 10 0,000 9,046E-03 0,02137374 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 9,046E-03 0,02135991 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 9,046E-03 0,02134609 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 9,046E-03 0,02133229 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 9,046E-03 0,02131851 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 9,046E-03 0,02130475 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 9,046E-03 0,021291 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 9,046E-03 0,02127728 ! transforming growth factor beta binding GO:0050431 11 10 0,000 9,046E-03 0,02126357 ! histidine metabolic process GO:0006547 10 10 0,000 9,046E-03 0,02124987 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 9,046E-03 0,0212362 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 9,046E-03 0,02122254 ! death receptor activity GO:0005035 11 10 0,000 9,046E-03 0,0212089 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 9,046E-03 0,02119528 ! entry into host cell GO:0030260 11 10 0,000 9,046E-03 0,02118168 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 9,046E-03 0,02116809 ! filamentous actin GO:0031941 11 10 0,000 9,046E-03 0,02115452 ! behavioral fear response GO:0001662 12 10 0,000 9,046E-03 0,02114097 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 9,046E-03 0,02112744 ! negative regulation of ossification GO:0030279 12 10 0,000 9,046E-03 0,02111392 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 9,046E-03 0,02110042 ! macrophage differentiation GO:0030225 11 10 0,000 9,046E-03 0,02108694 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 9,046E-03 0,02107347 ! recycling endosome membrane GO:0055038 11 10 0,000 9,046E-03 0,02106002 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 9,046E-03 0,02104659 ! snRNA metabolic process GO:0016073 10 10 0,000 9,046E-03 0,02103318 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 9,046E-03 0,02101978 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 9,046E-03 0,0210064 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 9,046E-03 0,02099304 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 9,046E-03 0,02097969 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 9,046E-03 0,02096636 ! nitric oxide metabolic process GO:0046209 20 10 0,000 9,046E-03 0,02095305 ! response to estradiol stimulus GO:0032355 11 10 0,000 9,046E-03 0,02093976 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 9,046E-03 0,02092648 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 9,046E-03 0,02091322 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 9,046E-03 0,02089997 ! MHC class II receptor activity GO:0032395 14 10 0,000 9,046E-03 0,02088674 ! peptidyl-lysine modification GO:0018205 11 10 0,000 9,046E-03 0,02087353 ! ribonuclease P activity GO:0004526 10 10 0,000 9,046E-03 0,02086034 ! COPI vesicle coat GO:0030126 12 10 0,000 9,046E-03 0,02084716 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 9,046E-03 0,020834 ! vitamin transporter activity GO:0051183 12 10 0,000 9,046E-03 0,02082085 ! snRNA binding GO:0017069 11 10 0,000 9,046E-03 0,02080773 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 9,046E-03 0,02079462 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 9,046E-03 0,02078152 ! fatty-acid ligase activity GO:0015645 10 10 0,000 9,046E-03 0,02076844 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 9,046E-03 0,02075538 ! quaternary ammonium group transport GO:0015697 10 10 0,000 9,046E-03 0,02074233 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 9,046E-03 0,02072931 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 9,046E-03 0,02071629 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 9,046E-03 0,0207033 ! regulation of RNA splicing GO:0043484 13 10 0,000 9,046E-03 0,02069032 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 9,046E-03 0,02067735 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 9,046E-03 0,0206644 ! extracellular matrix binding GO:0050840 11 10 0,000 9,046E-03 0,02065147 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 9,046E-03 0,02063856 ! autophagic vacuole formation GO:0000045 11 10 0,000 9,046E-03 0,02062566 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 9,046E-03 0,02061278 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 9,046E-03 0,02059991 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 9,046E-03 0,02058706 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 9,046E-03 0,02057422 ! DNA bending activity GO:0008301 11 10 0,000 9,046E-03 0,0205614 ! regulation of phosphatase activity GO:0010921 10 10 0,000 9,046E-03 0,0205486 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 9,046E-03 0,02053581 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 9,046E-03 0,02052304 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 9,046E-03 0,02051029 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 9,046E-03 0,02049755 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 9,046E-03 0,02048483 ! regulation of glycolysis GO:0006110 11 10 0,000 9,046E-03 0,02047212 ! nucleotidase activity GO:0008252 10 10 0,000 9,046E-03 0,02045943 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 9,046E-03 0,02044675 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 9,046E-03 0,02043409 ! androgen metabolic process GO:0008209 11 10 0,000 9,046E-03 0,02042144 ! lateral plasma membrane GO:0016328 13 10 0,000 9,046E-03 0,02040882 ! MAP kinase kinase activity GO:0004708 12 10 0,000 9,046E-03 0,0203962 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 9,046E-03 0,0203836 ! startle response GO:0001964 13 10 0,000 9,046E-03 0,02037102 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 9,046E-03 0,02035845 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 9,046E-03 0,0203459 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 9,046E-03 0,02033337 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 9,046E-03 0,02032085 ! spinal cord patterning GO:0021511 12 10 0,000 9,046E-03 0,02030834 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 9,046E-03 0,02029585 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 9,046E-03 0,02028338 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 9,046E-03 0,02027092 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 9,046E-03 0,02025847 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 9,046E-03 0,02024605 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 9,046E-03 0,02023363 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 9,046E-03 0,02022123 ! regulation of intracellular pH GO:0051453 10 10 0,000 9,046E-03 0,02020885 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 9,046E-03 0,02019648 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 9,046E-03 0,02018413 ! adult heart development GO:0007512 14 10 0,000 9,046E-03 0,02017179 ! neuromuscular junction development GO:0007528 12 10 0,000 9,046E-03 0,02015947 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 9,046E-03 0,02014716 ! O-methyltransferase activity GO:0008171 10 10 0,000 9,046E-03 0,02013487 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 9,046E-03 0,02012259 ! signalosome GO:0008180 10 10 0,000 9,046E-03 0,02011033 ! lysophospholipase activity GO:0004622 19 10 0,000 9,046E-03 0,02009808 ! prefoldin complex GO:0016272 10 10 0,000 9,046E-03 0,02008585 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 9,046E-03 0,02007363 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 9,046E-03 0,02006143 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 9,046E-03 0,02004924 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 9,046E-03 0,02003707 ! endocytic vesicle membrane GO:0030666 10 10 0,000 9,046E-03 0,02002491 ! gland morphogenesis GO:0022612 11 10 0,000 9,046E-03 0,02001277 ! icosanoid receptor activity GO:0004953 13 10 0,000 9,046E-03 0,02000064 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 9,046E-03 0,01998852 ! peptide transporter activity GO:0015197 10 10 0,000 9,046E-03 0,01997642 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 9,046E-03 0,01996434 ! regulation of leukocyte migration GO:0002685 11 10 0,000 9,046E-03 0,01995227 ! muscle maintenance GO:0046716 10 10 0,000 9,046E-03 0,01994021 ! acid secretion GO:0046717 12 10 0,000 9,046E-03 0,01992817 ! retinoid-X receptor activity GO:0004886 11 10 0,000 9,046E-03 0,01991615 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 9,046E-03 0,01990413 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 9,046E-03 0,01989214 ! GTPase inhibitor activity GO:0005095 21 10 0,000 9,046E-03 0,01988015 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 9,046E-03 0,01986818 ! pattern recognition receptor activity GO:0008329 10 10 0,000 9,046E-03 0,01985623 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 9,046E-03 0,01984429 ! regulation of organic acid transport GO:0032890 12 10 0,000 9,046E-03 0,01983236 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 9,046E-03 0,01982045 ! C-acyltransferase activity GO:0016408 12 10 0,000 9,046E-03 0,01980856 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 9,046E-03 0,01979667 ! water channel activity GO:0015250 15 10 0,000 9,046E-03 0,0197848 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 9,046E-03 0,01977295 ! regulation of embryonic development GO:0045995 12 10 0,000 9,046E-03 0,01976111 ! acrosome reaction GO:0007340 12 10 0,000 9,046E-03 0,01974928 ! mitochondrion localization GO:0051646 10 10 0,000 9,046E-03 0,01973747 ! cilium part GO:0044441 10 10 0,000 9,046E-03 0,01972567 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 9,947E-03 0,02167602 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 9,947E-03 0,02166308 ! negative regulation of blood pressure GO:0045776 13 11 0,000 9,947E-03 0,02165016 ! centriole GO:0005814 11 11 0,000 9,947E-03 0,02163725 ! cadmium ion binding GO:0046870 15 11 0,000 9,947E-03 0,02162435 ! hemoglobin complex GO:0005833 13 11 0,000 9,947E-03 0,02161147 ! CTP metabolic process GO:0046036 13 11 0,000 9,947E-03 0,02159861 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 9,947E-03 0,02158576 ! response to pain GO:0048265 12 11 0,000 9,947E-03 0,02157293 ! regulation of viral genome replication GO:0045069 13 11 0,000 9,947E-03 0,02156011 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 9,947E-03 0,0215473 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 9,947E-03 0,02153452 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 9,947E-03 0,02152174 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 9,947E-03 0,02150899 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 9,947E-03 0,02149624 ! peptide antigen binding GO:0042605 14 11 0,000 9,947E-03 0,02148352 ! polyamine metabolic process GO:0006595 11 11 0,000 9,947E-03 0,0214708 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 9,947E-03 0,02145811 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 9,947E-03 0,02144543 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 9,947E-03 0,02143276 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 9,947E-03 0,02142011 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 9,947E-03 0,02140747 ! protein homotetramerization GO:0051289 13 11 0,000 9,947E-03 0,02139485 ! regulation of gliogenesis GO:0014013 13 11 0,000 9,947E-03 0,02138224 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 9,947E-03 0,02136965 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 9,947E-03 0,02135707 ! regulation of circadian rhythm GO:0042752 11 11 0,000 9,947E-03 0,02134451 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 9,947E-03 0,02133196 ! response to dsRNA GO:0043331 21 11 0,000 9,947E-03 0,02131942 ! response to amine stimulus GO:0014075 15 11 0,000 9,947E-03 0,02130691 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 9,947E-03 0,0212944 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 9,947E-03 0,02128191 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 9,947E-03 0,02126944 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 9,947E-03 0,02125698 ! retinal binding GO:0016918 11 11 0,000 9,947E-03 0,02124453 ! leukocyte activation during immune response GO:0002366 11 11 0,000 9,947E-03 0,0212321 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 9,947E-03 0,02121968 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 9,947E-03 0,02120728 ! autonomic nervous system development GO:0048483 12 11 0,000 9,947E-03 0,0211949 ! negative regulation of lipid transport GO:0032369 12 11 0,000 9,947E-03 0,02118252 ! photoreceptor outer segment GO:0001750 12 11 0,000 9,947E-03 0,02117016 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 9,947E-03 0,02115782 ! peptidyl-threonine modification GO:0018210 15 11 0,000 9,947E-03 0,02114549 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 9,947E-03 0,02113317 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 9,947E-03 0,02112087 ! regulation of epidermis development GO:0045682 14 11 0,000 9,947E-03 0,02110859 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 9,947E-03 0,02109631 ! midbrain development GO:0030901 12 11 0,000 9,947E-03 0,02108406 ! musculoskeletal movement GO:0050881 12 11 0,000 9,947E-03 0,02107181 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 9,947E-03 0,02105958 ! regulation of RNA stability GO:0043487 13 11 0,000 9,947E-03 0,02104737 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 9,947E-03 0,02103517 ! cell killing GO:0001906 13 11 0,000 9,947E-03 0,02102298 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 9,947E-03 0,02101081 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 9,947E-03 0,02099865 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 9,947E-03 0,0209865 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 9,947E-03 0,02097437 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 9,947E-03 0,02096225 ! folic acid binding GO:0005542 12 11 0,000 9,947E-03 0,02095015 ! mRNA 3'-end processing GO:0031124 12 11 0,000 9,947E-03 0,02093806 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 9,947E-03 0,02092599 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 9,947E-03 0,02091393 ! microspike assembly GO:0030035 15 11 0,000 9,947E-03 0,02090188 ! lamellipodium assembly GO:0030032 22 11 0,000 9,947E-03 0,02088984 ! fibrillar collagen GO:0005583 12 11 0,000 9,947E-03 0,02087783 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 9,947E-03 0,02086582 ! negative regulation of muscle development GO:0048635 13 11 0,000 9,947E-03 0,02085383 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 9,947E-03 0,02084185 ! synaptonemal complex GO:0000795 11 11 0,000 9,947E-03 0,02082989 ! reproductive cellular process GO:0048610 13 11 0,000 9,947E-03 0,02081793 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 9,947E-03 0,020806 ! Golgi vesicle budding GO:0048194 12 11 0,000 9,947E-03 0,02079407 ! response to cAMP GO:0051591 11 11 0,000 9,947E-03 0,02078217 ! detection of mechanical stimulus GO:0050982 13 11 0,000 9,947E-03 0,02077027 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 9,947E-03 0,02075839 ! regulation of cell projection assembly GO:0060491 11 11 0,000 9,947E-03 0,02074652 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 9,947E-03 0,02073466 ! macromolecular complex remodeling GO:0034367 11 11 0,000 9,947E-03 0,02072282 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 9,947E-03 0,02071099 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 9,947E-03 0,02069918 ! drug transport GO:0015893 12 11 0,000 9,947E-03 0,02068738 ! FMN binding GO:0010181 12 11 0,000 9,947E-03 0,02067559 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 9,947E-03 0,02066382 ! water transporter activity GO:0005372 17 11 0,000 9,947E-03 0,02065205 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 9,947E-03 0,02064031 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 9,947E-03 0,02062857 ! multicellular organism growth GO:0035264 12 11 0,000 9,947E-03 0,02061685 ! integrator complex GO:0032039 11 11 0,000 9,947E-03 0,02060514 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 9,947E-03 0,02059345 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 12 11 0,000 9,947E-03 0,02058177 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 9,947E-03 0,0205701 ! negative regulation of caspase activity GO:0043154 12 11 0,000 9,947E-03 0,02055845 ! macroautophagy GO:0016236 12 11 0,000 9,947E-03 0,02054681 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 9,947E-03 0,02053518 ! neuromuscular junction GO:0031594 12 11 0,000 9,947E-03 0,02052356 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 9,947E-03 0,02051196 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 9,947E-03 0,02050037 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 9,947E-03 0,0204888 ! response to antibiotic GO:0046677 13 11 0,000 9,947E-03 0,02047723 ! protein-hormone receptor activity GO:0016500 12 11 0,000 9,947E-03 0,02046569 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 9,947E-03 0,02045415 ! proteasome accessory complex GO:0022624 11 11 0,000 9,947E-03 0,02044263 ! neuroblast proliferation GO:0007405 13 11 0,000 9,947E-03 0,02043112 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 9,947E-03 0,02041962 ! negative regulation of neurological system process GO:0031645 13 11 0,000 9,947E-03 0,02040813 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 9,947E-03 0,02039666 ! protein kinase C binding GO:0005080 11 11 0,000 9,947E-03 0,0203852 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 9,947E-03 0,02037376 ! male genitalia development GO:0030539 15 11 0,000 9,947E-03 0,02036232 ! receptor inhibitor activity GO:0030547 12 11 0,000 9,947E-03 0,0203509 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 9,947E-03 0,0203395 ! L-fucose metabolic process GO:0042354 13 11 0,000 9,947E-03 0,0203281 ! palmitoyltransferase activity GO:0016409 11 11 0,000 9,947E-03 0,02031672 ! arylsulfatase activity GO:0004065 12 11 0,000 9,947E-03 0,02030535 ! sterol transporter activity GO:0015248 11 11 0,000 9,947E-03 0,02029399 ! response to nicotine GO:0035094 13 11 0,000 9,947E-03 0,02028265 ! adenylate cyclase activity GO:0004016 11 11 0,000 9,947E-03 0,02027132 ! rRNA transcription GO:0009303 12 12 0,000 0,01084634 0,02209238 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01084634 0,02208005 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01084634 0,02206774 ! superoxide anion generation GO:0042554 12 12 0,000 0,01084634 0,02205544 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01084634 0,02204315 ! regulation of S phase GO:0033261 16 12 0,000 0,01084634 0,02203088 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01084634 0,02201862 ! male meiosis GO:0007140 12 12 0,000 0,01084634 0,02200637 ! signal complex assembly GO:0007172 15 12 0,000 0,01084634 0,02199414 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01084634 0,02198192 ! GTP metabolic process GO:0046039 14 12 0,000 0,01084634 0,02196972 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01084634 0,02195752 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01084634 0,02194535 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01084634 0,02193318 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01084634 0,02192103 ! cartilage condensation GO:0001502 14 12 0,000 0,01084634 0,02190889 ! polysome GO:0005844 14 12 0,000 0,01084634 0,02189677 ! hippocampus development GO:0021766 13 12 0,000 0,01084634 0,02188466 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01084634 0,02187256 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01084634 0,02186047 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01084634 0,0218484 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01084634 0,02183635 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01084634 0,0218243 ! chylomicron GO:0042627 13 12 0,000 0,01084634 0,02181227 ! T cell selection GO:0045058 22 12 0,000 0,01084634 0,02180025 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01084634 0,02178825 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01084634 0,02177626 ! WW domain binding GO:0050699 12 12 0,000 0,01084634 0,02176428 ! methionine metabolic process GO:0006555 14 12 0,000 0,01084634 0,02175231 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01084634 0,02174036 ! glycine metabolic process GO:0006544 14 12 0,000 0,01084634 0,02172842 ! plasma membrane organization GO:0007009 12 12 0,000 0,01084634 0,0217165 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01084634 0,02170458 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01084634 0,02169269 ! Golgi organization GO:0007030 15 12 0,000 0,01084634 0,0216808 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01084634 0,02166893 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01084634 0,02165706 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01084634 0,02164522 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01084634 0,02163338 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01084634 0,02162156 ! temperature homeostasis GO:0001659 13 12 0,000 0,01084634 0,02160975 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01084634 0,02159796 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01084634 0,02158617 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01084634 0,0215744 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01084634 0,02156265 ! axon cargo transport GO:0008088 13 12 0,000 0,01084634 0,0215509 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01084634 0,02153917 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01084634 0,02152745 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01084634 0,02151575 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01084634 0,02150405 ! basal lamina GO:0005605 12 12 0,000 0,01084634 0,02149237 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01084634 0,0214807 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01084634 0,02146905 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01084634 0,02145741 ! biomineral formation GO:0031214 14 12 0,000 0,01084634 0,02144578 ! water homeostasis GO:0030104 12 12 0,000 0,01084634 0,02143416 ! promoter binding GO:0010843 14 12 0,000 0,01084634 0,02142255 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01084634 0,02141096 ! intestinal absorption GO:0050892 14 12 0,000 0,01084634 0,02139938 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01084634 0,02138781 ! oocyte differentiation GO:0009994 13 12 0,000 0,01084634 0,02137626 ! oxygen transport GO:0015671 13 12 0,000 0,01084634 0,02136472 GO:0005344|oxygen transporter activity, ! cholesterol efflux GO:0033344 13 12 0,000 0,01084634 0,02135319 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01084634 0,02134167 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01084634 0,02133017 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01084634 0,02131867 ! tropomyosin binding GO:0005523 12 12 0,000 0,01084634 0,02130719 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01084634 0,02129573 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01084634 0,02128427 ! mannose binding GO:0005537 13 12 0,000 0,01084634 0,02127283 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01084634 0,0212614 ! defense response to fungus GO:0050832 12 12 0,000 0,01084634 0,02124998 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01084634 0,02123857 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01084634 0,02122718 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01084634 0,02121579 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01084634 0,02120443 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01084634 0,02119307 ! copper ion transport GO:0006825 12 12 0,000 0,01084634 0,02118172 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01084634 0,02117039 ! inositol metabolic process GO:0006020 21 12 0,000 0,01084634 0,02115907 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01084634 0,02114776 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01084634 0,02113646 ! protein complex disassembly GO:0043241 15 12 0,000 0,01084634 0,02112518 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01084634 0,0211139 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01084634 0,02110264 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01084634 0,0210914 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01084634 0,02108016 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01084634 0,02106893 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01084634 0,02105772 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01084634 0,02104652 ! endoderm development GO:0007492 13 12 0,000 0,01084634 0,02103533 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01084634 0,02102415 ! focal adhesion formation GO:0048041 16 12 0,000 0,01084634 0,02101299 ! T cell receptor complex GO:0042101 31 12 0,000 0,01084634 0,02100184 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01084634 0,02099069 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01084634 0,02097956 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01084634 0,02096845 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01084634 0,02095734 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01084634 0,02094625 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01084634 0,02093516 ! retinol binding GO:0019841 12 12 0,000 0,01084634 0,02092409 ! regulation of organ growth GO:0046620 12 12 0,000 0,01084634 0,02091303 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01084634 0,02090198 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01084634 0,02089095 ! histone acetylation GO:0016573 13 12 0,000 0,01084634 0,02087992 ! ribosome binding GO:0043022 13 12 0,000 0,01084634 0,02086891 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01084634 0,02085791 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01084634 0,02084692 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01084634 0,02083594 ! tissue regeneration GO:0042246 12 12 0,000 0,01084634 0,02082498 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01084634 0,02081402 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01084634 0,02080308 ! germ cell nucleus GO:0043073 14 12 0,000 0,01084634 0,02079215 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01084634 0,02078123 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01084634 0,02077032 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01084634 0,02075942 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01084634 0,02074854 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01084634 0,02073766 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01084634 0,0207268 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01084634 0,02071595 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01084634 0,02070511 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01084634 0,02069428 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01084634 0,02068346 ! bacterial binding GO:0008367 14 12 0,000 0,01084634 0,02067265 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01084634 0,02066186 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01084634 0,02065107 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01084634 0,0206403 ! localization within membrane GO:0051668 13 12 0,000 0,01084634 0,02062954 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01084634 0,02061879 ! axoneme part GO:0044447 12 12 0,000 0,01084634 0,02060805 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01174519 0,02230424 ! neuron maturation GO:0042551 14 13 0,000 0,01174519 0,02229264 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01174519 0,02228104 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01174519 0,02226946 ! bone remodeling GO:0046849 14 13 0,000 0,01174519 0,0222579 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01174519 0,02224634 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01174519 0,02223479 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01174519 0,02222326 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01174519 0,02221174 ! organelle fusion GO:0048284 16 13 0,000 0,01174519 0,02220023 ! palate development GO:0060021 15 13 0,000 0,01174519 0,02218874 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01174519 0,02217725 ! arginine metabolic process GO:0006525 14 13 0,000 0,01174519 0,02216578 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01174519 0,02215432 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01174519 0,02214287 ! response to retinoic acid GO:0032526 17 13 0,000 0,01174519 0,02213143 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01174519 0,02212 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01174519 0,02210859 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01174519 0,02209719 ! fear response GO:0042596 15 13 0,000 0,01174519 0,0220858 ! epithelial cell development GO:0002064 22 13 0,000 0,01174519 0,02207442 ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01174519 0,02206305 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01174519 0,0220517 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01174519 0,02204035 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01174519 0,02202902 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01174519 0,0220177 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01174519 0,02200639 ! cranial nerve development GO:0021545 15 13 0,000 0,01174519 0,0219951 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01174519 0,02198381 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01174519 0,02197254 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01174519 0,02196128 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01174519 0,02195002 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01174519 0,02193879 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01174519 0,02192756 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01174519 0,02191634 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01174519 0,02190514 ! NADP metabolic process GO:0006739 15 13 0,000 0,01174519 0,02189394 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01174519 0,02188276 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01174519 0,02187159 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01174519 0,02186043 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01174519 0,02184929 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01174519 0,02183815 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01174519 0,02182702 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01174519 0,02181591 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01174519 0,02180481 ! ADP binding GO:0043531 15 13 0,000 0,01174519 0,02179372 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01174519 0,02178264 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01174519 0,02177157 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01174519 0,02176051 ! neuron fate specification GO:0048665 25 13 0,000 0,01174519 0,02174947 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01174519 0,02173843 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01174519 0,02172741 ! water transport GO:0006833 18 13 0,000 0,01174519 0,0217164 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01174519 0,02170539 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01174519 0,0216944 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01174519 0,02168343 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01174519 0,02167246 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01174519 0,0216615 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01174519 0,02165055 ! myoblast differentiation GO:0045445 15 13 0,000 0,01174519 0,02163962 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01174519 0,0216287 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01174519 0,02161778 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01174519 0,02160688 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01174519 0,02159599 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01174519 0,02158511 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01174519 0,02157424 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01174519 0,02156339 ! exocrine system development GO:0035272 14 13 0,000 0,01174519 0,02155254 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01174519 0,0215417 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01174519 0,02153088 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01174519 0,02152006 ! L-glutamate transport GO:0015813 14 13 0,000 0,01174519 0,02150926 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01174519 0,02149847 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01174519 0,02148769 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01174519 0,02147692 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01174519 0,02146616 ! genitalia development GO:0048806 18 13 0,000 0,01174519 0,02145541 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01174519 0,02144467 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01174519 0,02143394 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01174519 0,02142322 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01174519 0,02141252 ! DNA methylation GO:0006306 15 13 0,000 0,01174519 0,02140182 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01174519 0,02139114 ! chromatin silencing GO:0006342 13 13 0,000 0,01174519 0,02138046 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01174519 0,0213698 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01174519 0,02135915 ! T cell homeostasis GO:0043029 14 13 0,000 0,01174519 0,0213485 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01174519 0,02133787 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01174519 0,02132725 ! response to gamma radiation GO:0010332 14 13 0,000 0,01174519 0,02131664 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01174519 0,02130604 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01174519 0,02129545 ! purine base metabolic process GO:0006144 15 13 0,000 0,01174519 0,02128487 ! cAMP binding GO:0030552 15 13 0,000 0,01174519 0,0212743 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01174519 0,02126375 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01174519 0,0212532 ! regulation of axon extension GO:0030516 16 13 0,000 0,01174519 0,02124266 ! drug transporter activity GO:0015238 14 13 0,000 0,01174519 0,02123213 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01174519 0,02122162 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01174519 0,02121111 ! response to cold GO:0009409 13 13 0,000 0,01174519 0,02120062 ! cadherin binding GO:0045296 16 13 0,000 0,01174519 0,02119013 ! nucleolar part GO:0044452 13 13 0,000 0,01174519 0,02117966 ! tRNA modification GO:0006400 14 14 0,000 0,01264327 0,02278786 ! cis-Golgi network GO:0005801 16 14 0,000 0,01264327 0,02277661 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01264327 0,02276537 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01264327 0,02275414 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01264327 0,02274292 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01264327 0,02273171 ! peroxisomal transport GO:0043574 14 14 0,000 0,01264327 0,02272051 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01264327 0,02270932 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01264327 0,02269815 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01264327 0,02268698 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01264327 0,02267583 ! negative regulation of peptidase activity GO:0010466 16 14 0,000 0,01264327 0,02266468 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01264327 0,02265355 ! positive regulation of cell growth GO:0030307 15 14 0,000 0,01264327 0,02264243 ! caspase activator activity GO:0008656 16 14 0,000 0,01264327 0,02263132 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01264327 0,02262022 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01264327 0,02260913 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01264327 0,02259806 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01264327 0,02258699 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01264327 0,02257593 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01264327 0,02256489 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01264327 0,02255386 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01264327 0,02254283 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01264327 0,02253182 ! response to vitamin A GO:0033189 18 14 0,000 0,01264327 0,02252082 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01264327 0,02250983 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01264327 0,02249885 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01264327 0,02248788 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01264327 0,02247692 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01264327 0,02246597 ! protein export from nucleus GO:0006611 14 14 0,000 0,01264327 0,02245503 ! presynaptic membrane GO:0042734 14 14 0,000 0,01264327 0,0224441 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01264327 0,02243319 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01264327 0,02242228 ! neural crest cell migration GO:0001755 15 14 0,000 0,01264327 0,02241139 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01264327 0,0224005 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01264327 0,02238963 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01264327 0,02237876 ! cofactor transport GO:0051181 16 14 0,000 0,01264327 0,02236791 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01264327 0,02235707 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01264327 0,02234624 ! cobalt ion binding GO:0050897 14 14 0,000 0,01264327 0,02233542 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01264327 0,0223246 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01264327 0,0223138 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01264327 0,02230301 ! gas transport GO:0015669 15 14 0,000 0,01264327 0,02229223 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01264327 0,02228147 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01264327 0,02227071 ! release of cytochrome c from mitochondria GO:0001836 26 14 0,000 0,01264327 0,02225996 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01264327 0,02224922 ! insulin secretion GO:0030073 17 14 0,000 0,01264327 0,02223849 ! tRNA binding GO:0000049 16 14 0,000 0,01264327 0,02222778 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01264327 0,02221707 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01264327 0,02220637 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01264327 0,02219569 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01264327 0,02218501 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01264327 0,02217434 ! MAP kinase activity GO:0004707 16 14 0,000 0,01264327 0,02216369 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01264327 0,02215304 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01264327 0,02214241 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01264327 0,02213178 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01264327 0,02212117 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01264327 0,02211056 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01264327 0,02209997 ! response to osmotic stress GO:0006970 17 14 0,000 0,01264327 0,02208938 ! fructose metabolic process GO:0006000 15 14 0,000 0,01264327 0,02207881 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01264327 0,02206825 ! monoamine transport GO:0015844 15 14 0,000 0,01264327 0,02205769 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01264327 0,02204715 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01264327 0,02203661 ! dendritic spine GO:0043197 15 14 0,000 0,01264327 0,02202609 ! stem cell development GO:0048864 14 14 0,000 0,01264327 0,02201558 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01264327 0,02200507 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01264327 0,02199458 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01264327 0,0219841 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01264327 0,02197362 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01264327 0,02196316 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01264327 0,02195271 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01264327 0,02194226 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01264327 0,02193183 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01264327 0,0219214 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01264327 0,02191099 ! mannosidase activity GO:0015923 19 14 0,000 0,01264327 0,02190059 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01264327 0,02189019 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01264327 0,02187981 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01264327 0,02186943 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01264327 0,02185907 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01264327 0,02184871 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01264327 0,02183837 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01264327 0,02182803 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01264327 0,02181771 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01264327 0,02180739 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01264327 0,02179709 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01264327 0,02178679 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01264327 0,0217765 ! positive regulation of translation GO:0045727 17 15 0,000 0,01354057 0,023311 ! nuclear replication fork GO:0043596 26 15 0,000 0,01354057 0,02330001 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01354057 0,02328902 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01354057 0,02327805 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01354057 0,02326708 ! endothelial cell migration GO:0043542 16 15 0,000 0,01354057 0,02325613 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01354057 0,02324518 ! response to vitamin GO:0033273 19 15 0,000 0,01354057 0,02323425 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01354057 0,02322333 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01354057 0,02321241 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01354057 0,02320151 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01354057 0,02319062 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01354057 0,02317974 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01354057 0,02316886 ! pituitary gland development GO:0021983 16 15 0,000 0,01354057 0,023158 ! cholesterol binding GO:0015485 15 15 0,000 0,01354057 0,02314715 ! NAD metabolic process GO:0019674 17 15 0,000 0,01354057 0,02313631 ! protease binding GO:0002020 20 15 0,000 0,01354057 0,02312548 ! regulation of heart rate GO:0002027 20 15 0,000 0,01354057 0,02311465 ! actin filament bundle GO:0032432 18 15 0,000 0,01354057 0,02310384 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,01354057 0,02309304 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01354057 0,02308225 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01354057 0,02307147 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01354057 0,0230607 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01354057 0,02304994 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01354057 0,02303919 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01354057 0,02302845 ! neuron recognition GO:0008038 18 15 0,000 0,01354057 0,02301772 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01354057 0,02300699 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01354057 0,02299628 ! filopodium GO:0030175 17 15 0,000 0,01354057 0,02298558 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01354057 0,02297489 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01354057 0,02296421 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01354057 0,02295354 ! peptide hormone binding GO:0017046 16 15 0,000 0,01354057 0,02294288 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01354057 0,02293223 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01354057 0,02292159 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01354057 0,02291095 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01354057 0,02290033 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01354057 0,02288972 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01354057 0,02287912 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01354057 0,02286853 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01354057 0,02285794 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01354057 0,02284737 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01354057 0,02283681 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01354057 0,02282626 ! lactation GO:0007595 17 15 0,000 0,01354057 0,02281571 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01354057 0,02280518 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01354057 0,02279466 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01354057 0,02278414 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01354057 0,02277364 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01354057 0,02276314 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01354057 0,02275266 ! sulfate transport GO:0008272 16 15 0,000 0,01354057 0,02274218 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01354057 0,02273172 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01354057 0,02272126 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01354057 0,02271081 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01354057 0,02270038 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01354057 0,02268995 ! heart looping GO:0001947 18 15 0,000 0,01354057 0,02267953 ! protein kinase C activity GO:0004697 17 15 0,000 0,01354057 0,02266912 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01354057 0,02265872 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01354057 0,02264833 ! pigmentation during development GO:0048066 17 15 0,000 0,01354057 0,02263795 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01354057 0,02262758 ! vesicle coating GO:0006901 17 15 0,000 0,01354057 0,02261722 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01354057 0,02260687 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01354057 0,02259653 ! L-amino acid transport GO:0015807 16 15 0,000 0,01354057 0,0225862 ! microfilament motor activity GO:0000146 15 15 0,000 0,01354057 0,02257588 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01354057 0,02256556 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01354057 0,02255526 ! DNA replication initiation GO:0006270 15 15 0,000 0,01354057 0,02254496 ! taste receptor activity GO:0008527 15 15 0,000 0,01354057 0,02253468 ! cellular pigmentation GO:0033059 16 15 0,000 0,01354057 0,0225244 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01354057 0,02251414 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01354057 0,02250388 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01354057 0,02249363 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01354057 0,02248339 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01354057 0,02247317 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01354057 0,02246295 ! ion gated channel activity GO:0022839 17 15 0,000 0,01354057 0,02245274 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01354057 0,02244253 ! receptor activator activity GO:0030546 17 15 0,000 0,01354057 0,02243234 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01354057 0,02242216 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01354057 0,02241199 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01354057 0,02240182 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01354057 0,02239167 ! peptide hormone processing GO:0016486 19 15 0,000 0,01354057 0,02238152 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01354057 0,02237138 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01443712 0,02384183 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01443712 0,02383104 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01443712 0,02382026 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01443712 0,02380949 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01443712 0,02379874 ! kinesin complex GO:0005871 16 16 0,000 0,01443712 0,02378799 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01443712 0,02377725 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01443712 0,02376652 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01443712 0,0237558 ! centrosome cycle GO:0007098 26 16 0,000 0,01443712 0,02374509 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01443712 0,02373439 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01443712 0,02372369 ! cerebral cortex development GO:0021987 16 16 0,000 0,01443712 0,02371301 ! lysosomal transport GO:0007041 16 16 0,000 0,01443712 0,02370234 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01443712 0,02369168 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01443712 0,02368103 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01443712 0,02367038 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01443712 0,02365975 ! myofibril assembly GO:0030239 17 16 0,000 0,01443712 0,02364912 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,01443712 0,02363851 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01443712 0,02362791 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01443712 0,02361731 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01443712 0,02360672 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01443712 0,02359615 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01443712 0,02358558 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01443712 0,02357502 ! steroid catabolic process GO:0006706 18 16 0,000 0,01443712 0,02356447 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01443712 0,02355394 ! cell-cell recognition GO:0009988 19 16 0,000 0,01443712 0,02354341 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01443712 0,02353289 ! spleen development GO:0048536 19 16 0,000 0,01443712 0,02352238 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01443712 0,02351188 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01443712 0,02350138 ! neural tube closure GO:0001843 19 16 0,000 0,01443712 0,0234909 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01443712 0,02348043 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,01443712 0,02346996 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01443712 0,02345951 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01443712 0,02344907 ! viral genome replication GO:0019079 16 16 0,000 0,01443712 0,02343863 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01443712 0,0234282 ! memory GO:0007613 18 16 0,000 0,01443712 0,02341779 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01443712 0,02340738 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01443712 0,02339698 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01443712 0,02338659 ! glycoprotein binding GO:0001948 19 16 0,000 0,01443712 0,02337621 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01443712 0,02336584 ! syntaxin binding GO:0019905 18 16 0,000 0,01443712 0,02335548 ! myosin binding GO:0017022 17 16 0,000 0,01443712 0,02334512 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01443712 0,02333478 ! fucose metabolic process GO:0006004 18 16 0,000 0,01443712 0,02332445 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01443712 0,02331412 ! membrane budding GO:0006900 18 16 0,000 0,01443712 0,02330381 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01443712 0,0232935 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01443712 0,0232832 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01443712 0,02327291 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01443712 0,02326263 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01443712 0,02325236 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,01443712 0,0232421 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01443712 0,02323185 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01443712 0,02322161 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01443712 0,02321137 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01443712 0,02320115 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01443712 0,02319093 ! axoneme GO:0005930 16 16 0,000 0,01443712 0,02318072 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01443712 0,02317052 ! anion exchanger activity GO:0015380 17 17 0,000 0,01533289 0,02459736 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01533289 0,02458654 ! skin development GO:0043588 20 17 0,000 0,01533289 0,02457574 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01533289 0,02456495 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01533289 0,02455416 ! glial cell development GO:0021782 17 17 0,000 0,01533289 0,02454339 ! limbic system development GO:0021761 18 17 0,000 0,01533289 0,02453263 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01533289 0,02452187 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01533289 0,02451112 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01533289 0,02450039 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01533289 0,02448966 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01533289 0,02447894 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01533289 0,02446824 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01533289 0,02445754 ! signal sequence binding GO:0005048 18 17 0,000 0,01533289 0,02444685 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01533289 0,02443617 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01533289 0,0244255 ! organelle subcompartment GO:0031984 19 17 0,000 0,01533289 0,02441484 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,01533289 0,02440418 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01533289 0,02439354 ! membrane depolarization GO:0051899 19 17 0,000 0,01533289 0,02438291 ! oogenesis GO:0048477 20 17 0,000 0,01533289 0,02437228 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01533289 0,02436167 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01533289 0,02435106 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01533289 0,02434046 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01533289 0,02432988 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01533289 0,0243193 ! organic cation transport GO:0015695 17 17 0,000 0,01533289 0,02430873 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01533289 0,02429817 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01533289 0,02428762 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01533289 0,02427708 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01533289 0,02426655 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01533289 0,02425602 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01533289 0,02424551 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01533289 0,024235 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01533289 0,02422451 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01533289 0,02421402 ! lipid localization GO:0010876 19 17 0,000 0,01533289 0,02420354 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01533289 0,02419307 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01533289 0,02418261 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01533289 0,02417216 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01533289 0,02416172 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01533289 0,02415129 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01533289 0,02414087 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01533289 0,02413045 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01533289 0,02412005 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01533289 0,02410965 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01533289 0,02409926 ! AMP binding GO:0016208 19 17 0,000 0,01533289 0,02408888 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01533289 0,02407851 ! receptor metabolic process GO:0043112 20 17 0,000 0,01533289 0,02406815 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01533289 0,0240578 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01533289 0,02404746 ! alcohol binding GO:0043178 20 17 0,000 0,01533289 0,02403712 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01533289 0,0240268 ! visual learning GO:0008542 31 17 0,000 0,01533289 0,02401648 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01533289 0,02400617 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01533289 0,02399588 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01533289 0,02398559 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01533289 0,02397531 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01533289 0,02396503 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01533289 0,02395477 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01533289 0,02394452 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01533289 0,02393427 ! histone binding GO:0042393 26 17 0,000 0,01533289 0,02392403 ! cilium assembly GO:0042384 18 17 0,000 0,01533289 0,0239138 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01533289 0,02390358 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01533289 0,02389337 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01533289 0,02388317 ! protein secretion GO:0009306 19 18 0,000 0,0162279 0,02526649 ! positive regulation of cell size GO:0045793 19 18 0,000 0,0162279 0,02525571 ! positive regulation of ossification GO:0045778 19 18 0,000 0,0162279 0,02524494 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,0162279 0,02523418 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,0162279 0,02522342 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid acetylation GO:0006473 21 18 0,000 0,0162279 0,02521268 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,0162279 0,02520195 ! cAMP metabolic process GO:0046058 18 18 0,000 0,0162279 0,02519122 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,0162279 0,02518051 ! cornified envelope GO:0001533 22 18 0,000 0,0162279 0,0251698 ! retinoid metabolic process GO:0001523 19 18 0,000 0,0162279 0,02515911 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,0162279 0,02514842 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,0162279 0,02513774 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,0162279 0,02512707 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,0162279 0,02511641 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,0162279 0,02510576 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,0162279 0,02509512 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,0162279 0,02508448 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,0162279 0,02507386 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,0162279 0,02506324 ! primary neural tube formation GO:0014020 21 18 0,000 0,0162279 0,02505264 ! recycling endosome GO:0055037 22 18 0,000 0,0162279 0,02504204 ! muscle cell development GO:0055001 20 18 0,000 0,0162279 0,02503145 ! kinase activator activity GO:0019209 22 18 0,000 0,0162279 0,02502087 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,0162279 0,0250103 ! cerebellum development GO:0021549 20 18 0,000 0,0162279 0,02499974 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,0162279 0,02498918 ! somitogenesis GO:0001756 20 18 0,000 0,0162279 0,02497864 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,0162279 0,02496811 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,0162279 0,02495758 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,0162279 0,02494706 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,0162279 0,02493655 ! basal plasma membrane GO:0009925 21 18 0,000 0,0162279 0,02492605 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,0162279 0,02491556 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,0162279 0,02490508 ! negative regulation of translation GO:0017148 31 18 0,000 0,0162279 0,02489461 ! regulation of cell killing GO:0031341 24 18 0,000 0,0162279 0,02488414 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,0162279 0,02487369 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,0162279 0,02486324 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,0162279 0,0248528 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,0162279 0,02484237 ! protein complex scaffold GO:0032947 22 18 0,000 0,0162279 0,02483195 ! SNAP receptor activity GO:0005484 21 18 0,000 0,0162279 0,02482154 ! dendrite development GO:0016358 22 18 0,000 0,0162279 0,02481114 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,0162279 0,02480074 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,0162279 0,02479036 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,0162279 0,02477998 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,0162279 0,02476961 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,0162279 0,02475925 ! coreceptor activity GO:0015026 28 18 0,000 0,0162279 0,0247489 ! response to fungus GO:0009620 18 18 0,000 0,0162279 0,02473856 ! stem cell differentiation GO:0048863 18 18 0,000 0,0162279 0,02472823 ! intermediate filament-based process GO:0045103 18 18 0,000 0,0162279 0,0247179 ! heart process GO:0003015 19 18 0,000 0,0162279 0,02470759 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,0162279 0,02469728 ! vasodilation GO:0042311 20 18 0,000 0,0162279 0,02468698 ! transport vesicle membrane GO:0030658 23 18 0,000 0,0162279 0,02467669 ! MHC protein binding GO:0042287 30 18 0,000 0,0162279 0,02466641 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,0162279 0,02465613 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,0162279 0,02464587 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,0162279 0,02463561 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,0162279 0,02462537 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,0162279 0,02461513 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,0162279 0,0246049 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,0162279 0,02459467 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,0162279 0,02458446 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,01712214 0,02592842 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,01712214 0,02591767 ! proteasome core complex GO:0005839 20 19 0,000 0,01712214 0,02590692 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,01712214 0,02589618 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,01712214 0,02588544 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,01712214 0,02587472 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,01712214 0,02586401 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,01712214 0,0258533 ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,01712214 0,0258426 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,01712214 0,02583192 ! lysosome organization GO:0007040 20 19 0,000 0,01712214 0,02582124 ! central nervous system neuron development GO:0021954 21 19 0,000 0,01712214 0,02581057 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,01712214 0,02579991 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,01712214 0,02578925 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,01712214 0,02577861 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,01712214 0,02576798 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,01712214 0,02575735 ! peptide cross-linking GO:0018149 23 19 0,000 0,01712214 0,02574673 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,01712214 0,02573612 ! beta-catenin binding GO:0008013 23 19 0,000 0,01712214 0,02572552 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,01712214 0,02571493 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,01712214 0,02570435 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01712214 0,02569378 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,01712214 0,02568321 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,01712214 0,02567266 ! vitamin transport GO:0051180 21 19 0,000 0,01712214 0,02566211 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,01712214 0,02565157 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,01712214 0,02564104 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,01712214 0,02563052 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,01712214 0,02562001 ! retinoid binding GO:0005501 19 19 0,000 0,01712214 0,0256095 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,01712214 0,02559901 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,01712214 0,02558852 ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,01712214 0,02557804 ! gluconeogenesis GO:0006094 23 19 0,000 0,01712214 0,02556757 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,01712214 0,02555711 ! microtubule-based transport GO:0010970 20 19 0,000 0,01712214 0,02554666 ! superoxide metabolic process GO:0006801 21 19 0,000 0,01712214 0,02553621 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,01712214 0,02552578 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01712214 0,02551535 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,01712214 0,02550493 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,01712214 0,02549452 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,01712214 0,02548412 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,01712214 0,02547373 ! acetylcholine binding GO:0042166 20 19 0,000 0,01712214 0,02546334 ! heme metabolic process GO:0042168 20 19 0,000 0,01712214 0,02545296 ! SH2 domain binding GO:0042169 25 19 0,000 0,01712214 0,0254426 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,01712214 0,02543224 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,01712214 0,02542189 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,01712214 0,02541154 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,01712214 0,02540121 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,01712214 0,02539088 ! body fluid secretion GO:0007589 21 19 0,000 0,01712214 0,02538057 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,01712214 0,02537026 ! secretory granule membrane GO:0030667 21 19 0,000 0,01712214 0,02535996 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,01712214 0,02534967 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,01712214 0,02533938 ! peptidase activator activity GO:0016504 21 19 0,000 0,01712214 0,02532911 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01712214 0,02531884 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,01712214 0,02530858 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,01712214 0,02529833 ! sialyltransferase activity GO:0008373 31 19 0,000 0,01712214 0,02528809 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,01712214 0,02527785 ! chaperone binding GO:0051087 21 20 0,000 0,01801562 0,02658616 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,01801562 0,02657541 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,01801562 0,02656466 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,01801562 0,02655393 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,01801562 0,02654321 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,01801562 0,02653249 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,01801562 0,02652178 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,01801562 0,02651109 ! ovarian follicle development GO:0001541 21 20 0,000 0,01801562 0,0265004 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,01801562 0,02648971 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,01801562 0,02647904 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,01801562 0,02646838 ! diencephalon development GO:0021536 22 20 0,000 0,01801562 0,02645772 ! regulation of lipid transport GO:0032368 22 20 0,000 0,01801562 0,02644707 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,01801562 0,02643644 ! glutathione metabolic process GO:0006749 21 20 0,000 0,01801562 0,02642581 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,01801562 0,02641519 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,01801562 0,02640457 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,01801562 0,02639397 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,01801562 0,02638337 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,01801562 0,02637279 ! peptide hormone secretion GO:0030072 25 20 0,000 0,01801562 0,02636221 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,01801562 0,02635164 ! Rab GTPase binding GO:0017137 22 20 0,000 0,01801562 0,02634107 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,01801562 0,02633052 ! heterochromatin GO:0000792 20 20 0,000 0,01801562 0,02631998 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,01801562 0,02630944 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,01801562 0,02629891 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,01801562 0,02628839 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,01801562 0,02627788 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,01801562 0,02626738 ! visual behavior GO:0007632 34 20 0,000 0,01801562 0,02625688 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,01801562 0,0262464 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,01801562 0,02623592 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,01801562 0,02622545 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,01801562 0,02621499 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,01801562 0,02620454 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,01801562 0,02619409 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,01801562 0,02618366 ! rRNA binding GO:0019843 22 20 0,000 0,01801562 0,02617323 ! cytolysis GO:0019835 22 20 0,000 0,01801562 0,02616281 ! renal system process GO:0003014 22 20 0,000 0,01801562 0,0261524 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,01801562 0,026142 ! fatty acid transport GO:0015908 23 20 0,000 0,01801562 0,0261316 ! transaminase activity GO:0008483 22 20 0,000 0,01801562 0,02612122 ! collagen catabolic process GO:0030574 21 20 0,000 0,01801562 0,02611084 ! microvillus GO:0005902 25 20 0,000 0,01801562 0,02610047 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,01801562 0,02609011 ! connexon complex GO:0005922 23 20 0,000 0,01801562 0,02607975 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,01890833 0,02736121 ! translational initiation GO:0006413 21 21 0,000 0,01890833 0,02735036 ! NF-kappaB binding GO:0051059 31 21 0,000 0,01890833 0,02733952 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,01890833 0,02732868 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,01890833 0,02731786 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,01890833 0,02730705 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,01890833 0,02729624 ! glutathione transferase activity GO:0004364 21 21 0,000 0,01890833 0,02728544 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,01890833 0,02727465 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,01890833 0,02726387 ! regeneration GO:0031099 24 21 0,000 0,01890833 0,0272531 ! apoptotic mitochondrial changes GO:0008637 33 21 0,000 0,01890833 0,02724234 ! MHC class I protein complex GO:0042612 31 21 0,000 0,01890833 0,02723158 ! cellular response to starvation GO:0009267 22 21 0,000 0,01890833 0,02722084 ! peroxisome organization GO:0007031 22 21 0,000 0,01890833 0,0272101 ! vacuole organization GO:0007033 23 21 0,000 0,01890833 0,02719937 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,01890833 0,02718865 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,01890833 0,02717793 ! neural crest cell development GO:0014032 24 21 0,000 0,01890833 0,02716723 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,01890833 0,02715653 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,01890833 0,02714585 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,01890833 0,02713517 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01890833 0,0271245 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,01890833 0,02711384 ! pallium development GO:0021543 22 21 0,000 0,01890833 0,02710318 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,01890833 0,02709254 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,01890833 0,0270819 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,01890833 0,02707127 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,01890833 0,02706065 ! cyclase activity GO:0009975 22 21 0,000 0,01890833 0,02705004 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,01890833 0,02703943 ! gut development GO:0048565 23 21 0,000 0,01890833 0,02702884 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,01890833 0,02701825 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,01890833 0,02700767 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01890833 0,0269971 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,01890833 0,02698654 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01890833 0,02697599 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,01890833 0,02696544 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,01890833 0,0269549 ! response to alkaloid GO:0043279 27 21 0,000 0,01890833 0,02694437 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,01890833 0,02693385 ! response to ethanol GO:0045471 28 21 0,000 0,01890833 0,02692334 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,01890833 0,02691284 ! smooth muscle contraction GO:0006939 25 21 0,000 0,01890833 0,02690234 ! ubiquitin binding GO:0043130 25 21 0,000 0,01890833 0,02689185 ! vesicle targeting GO:0006903 22 21 0,000 0,01890833 0,02688137 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,01890833 0,0268709 ! SNARE binding GO:0000149 24 21 0,000 0,01890833 0,02686044 ! interaction with host GO:0051701 26 21 0,000 0,01890833 0,02684998 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,01890833 0,02683953 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,01890833 0,02682909 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,01890833 0,02681866 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,01890833 0,02680824 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,01890833 0,02679782 ! cell-cell junction organization GO:0045216 24 21 0,000 0,01890833 0,02678742 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,01890833 0,02677702 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,01890833 0,02676663 ! caveola GO:0005901 25 21 0,000 0,01890833 0,02675624 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,01890833 0,02674587 ! insulin receptor binding GO:0005158 25 21 0,000 0,01890833 0,0267355 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,01890833 0,02672514 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01890833 0,02671479 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,01980028 0,02796416 ! metencephalon development GO:0022037 25 22 0,000 0,01980028 0,02795334 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,01980028 0,02794253 ! hormone secretion GO:0046879 28 22 0,000 0,01980028 0,02793172 ! vesicle docking GO:0048278 24 22 0,000 0,01980028 0,02792092 ! muscle myosin complex GO:0005859 23 22 0,000 0,01980028 0,02791013 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,01980028 0,02789935 ! actomyosin structure organization GO:0031032 24 22 0,000 0,01980028 0,02788858 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,01980028 0,02787782 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,01980028 0,02786706 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 0,000 0,01980028 0,02785632 ! sperm motility GO:0030317 23 22 0,000 0,01980028 0,02784558 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,01980028 0,02783485 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,01980028 0,02782413 ! vacuolar transport GO:0007034 22 22 0,000 0,01980028 0,02781341 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,01980028 0,02780271 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,01980028 0,02779201 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,01980028 0,02778132 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,01980028 0,02777064 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,01980028 0,02775996 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,01980028 0,0277493 ! PML body GO:0016605 25 22 0,000 0,01980028 0,02773864 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,01980028 0,027728 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,01980028 0,02771736 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,01980028 0,02770672 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,01980028 0,0276961 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,01980028 0,02768548 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,01980028 0,02767488 ! pentose metabolic process GO:0019321 23 22 0,000 0,01980028 0,02766428 ! collagen fibril organization GO:0030199 32 22 0,000 0,01980028 0,02765369 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,01980028 0,0276431 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,01980028 0,02763253 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,01980028 0,02762196 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,01980028 0,0276114 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,01980028 0,02760085 ! positive regulation of behavior GO:0048520 24 22 0,000 0,01980028 0,02759031 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,01980028 0,02757977 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,01980028 0,02756925 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,01980028 0,02755873 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,01980028 0,02754822 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,01980028 0,02753772 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,01980028 0,02752722 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,01980028 0,02751673 ! glycerol metabolic process GO:0006071 24 22 0,000 0,01980028 0,02750626 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,01980028 0,02749579 ! nuclear chromatin GO:0000790 23 22 0,000 0,01980028 0,02748532 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,01980028 0,02747487 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,01980028 0,02746442 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,01980028 0,02745398 ! sterol binding GO:0032934 24 22 0,000 0,01980028 0,02744355 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,01980028 0,02743313 ! digestive system process GO:0022600 25 22 0,000 0,01980028 0,02742271 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,01980028 0,02741231 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,01980028 0,02740191 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,01980028 0,02739152 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,01980028 0,02738113 ! DNA modification GO:0006304 25 22 0,000 0,01980028 0,02737076 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,01980028 0,02736039 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,01980028 0,02735003 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,01980028 0,02733968 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,01980028 0,02732933 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,01980028 0,027319 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,01980028 0,02730867 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,01980028 0,02729835 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,01980028 0,02728804 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02069147 0,02850547 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02069147 0,02849471 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02069147 0,02848395 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02069147 0,02847321 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02069147 0,02846247 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02069147 0,02845174 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02069147 0,02844102 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02069147 0,02843031 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02069147 0,02841961 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02069147 0,02840891 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02069147 0,02839822 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02069147 0,02838754 ! deaminase activity GO:0019239 24 23 0,000 0,02069147 0,02837687 ! sensory perception of pain GO:0019233 26 23 0,000 0,02069147 0,02836621 ! lipid kinase activity GO:0001727 26 23 0,000 0,02069147 0,02835555 ! platelet activation GO:0030168 27 23 0,000 0,02069147 0,0283449 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02069147 0,02833426 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02069147 0,02832363 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02069147 0,02831301 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02069147 0,02830239 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02069147 0,02829178 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02069147 0,02828118 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02069147 0,02827059 ! cell surface binding GO:0043498 28 23 0,000 0,02069147 0,02826001 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02069147 0,02824943 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02069147 0,02823886 ! regulation of glucose import GO:0046324 28 23 0,000 0,02069147 0,0282283 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02069147 0,02821775 ! alditol metabolic process GO:0019400 25 23 0,000 0,02069147 0,0282072 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02069147 0,02819667 ! zinc ion transport GO:0006829 26 23 0,000 0,02069147 0,02818614 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02069147 0,02817562 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02069147 0,0281651 ! sex determination GO:0007530 25 23 0,000 0,02069147 0,0281546 ! phosphate binding GO:0042301 25 23 0,000 0,02069147 0,0281441 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02069147 0,02813361 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02069147 0,02812313 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02069147 0,02811265 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02069147 0,02810219 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02069147 0,02809173 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,02069147 0,02808128 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,02069147 0,02807083 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02069147 0,0280604 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02069147 0,02804997 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02069147 0,02803955 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02069147 0,02802914 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02069147 0,02801874 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02069147 0,02800834 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02158189 0,0292028 ! actin filament GO:0005884 26 24 0,000 0,02158189 0,02919197 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02158189 0,02918115 ! pancreas development GO:0031016 27 24 0,000 0,02158189 0,02917034 ! androgen receptor binding GO:0050681 34 24 0,000 0,02158189 0,02915953 ! calcium channel complex GO:0034704 31 24 0,000 0,02158189 0,02914874 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02158189 0,02913795 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02158189 0,02912717 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02158189 0,0291164 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02158189 0,02910563 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02158189 0,02909488 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02158189 0,02908413 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02158189 0,02907339 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02158189 0,02906266 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02158189 0,02905193 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02158189 0,02904122 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02158189 0,02903051 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02158189 0,02901981 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02158189 0,02900912 ! protein stabilization GO:0050821 24 24 0,000 0,02158189 0,02899843 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02158189 0,02898775 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02158189 0,02897708 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,02158189 0,02896642 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02158189 0,02895577 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02158189 0,02894512 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02158189 0,02893449 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02158189 0,02892386 ! chemokine binding GO:0019956 26 24 0,000 0,02158189 0,02891324 ! catechol metabolic process GO:0009712 29 24 0,000 0,02158189 0,02890262 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02158189 0,02889201 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02158189 0,02888142 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02158189 0,02887082 ! cell aging GO:0007569 47 24 0,000 0,02158189 0,02886024 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02158189 0,02884967 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02158189 0,0288391 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02158189 0,02882854 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02158189 0,02881799 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02158189 0,02880744 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02158189 0,02879691 ! caspase regulator activity GO:0043028 26 24 0,000 0,02158189 0,02878638 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02158189 0,02877586 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02158189 0,02876534 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,02158189 0,02875484 ! selenium binding GO:0008430 24 24 0,000 0,02158189 0,02874434 ! spindle pole GO:0000922 35 24 0,000 0,02158189 0,02873385 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02158189 0,02872336 ! phenol metabolic process GO:0018958 31 25 0,000 0,02247155 0,02989651 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02247155 0,02988561 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02247155 0,02987472 ! aromatase activity GO:0070330 28 25 0,000 0,02247155 0,02986383 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02247155 0,02985296 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02247155 0,02984209 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02247155 0,02983123 ! response to starvation GO:0042594 26 25 0,000 0,02247155 0,02982038 ! dynein complex GO:0030286 28 25 0,000 0,02247155 0,02980954 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02247155 0,0297987 ! regulation of behavior GO:0050795 27 25 0,000 0,02247155 0,02978787 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02247155 0,02977705 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02247155 0,02976624 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02247155 0,02975544 ! hormone transport GO:0009914 31 25 0,000 0,02247155 0,02974464 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02247155 0,02973385 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02247155 0,02972307 ! regulation of coagulation GO:0050818 28 25 0,000 0,02247155 0,0297123 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02247155 0,02970153 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02247155 0,02969077 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02247155 0,02968002 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02247155 0,02966928 ! molting cycle process GO:0022404 28 25 0,000 0,02247155 0,02965855 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02247155 0,02964782 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02247155 0,0296371 ! phototransduction GO:0007602 27 25 0,000 0,02247155 0,02962639 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02247155 0,02961569 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02247155 0,02960499 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02247155 0,0295943 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02247155 0,02958362 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02247155 0,02957295 ! autophagy GO:0006914 28 25 0,000 0,02247155 0,02956229 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02247155 0,02955163 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02247155 0,02954098 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02247155 0,02953034 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02336045 0,03068741 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,02336045 0,03067636 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,02336045 0,03066532 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02336045 0,03065429 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02336045 0,03064327 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02336045 0,03063225 ! hair cycle GO:0042633 29 26 0,000 0,02336045 0,03062125 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02336045 0,03061025 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02336045 0,03059926 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02336045 0,03058827 ! early endosome membrane GO:0031901 31 26 0,000 0,02336045 0,0305773 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02336045 0,03056633 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02336045 0,03055537 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02336045 0,03054442 ! GABA receptor activity GO:0016917 31 26 0,000 0,02336045 0,03053348 ! PDZ domain binding GO:0030165 28 26 0,000 0,02336045 0,03052254 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02336045 0,03051161 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02336045 0,03050069 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02336045 0,03048978 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02336045 0,03047887 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02336045 0,03046798 ! fatty acid binding GO:0005504 28 26 0,000 0,02336045 0,03045709 ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,02336045 0,03044621 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02336045 0,03043533 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,02336045 0,03042447 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02336045 0,03041361 ! iron ion transport GO:0006826 33 26 0,000 0,02336045 0,03040276 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02336045 0,03039192 ! glucose transport GO:0015758 27 26 0,000 0,02336045 0,03038108 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,02336045 0,03037025 ! spinal cord development GO:0021510 30 26 0,000 0,02336045 0,03035943 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02336045 0,03034862 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02336045 0,03033782 ! RNA helicase activity GO:0003724 46 26 0,000 0,02336045 0,03032702 ! brush border GO:0005903 30 26 0,000 0,02336045 0,03031623 ! gap junction GO:0005921 29 26 0,000 0,02336045 0,03030545 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02336045 0,03029468 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,02424859 0,03143527 ! RNA export from nucleus GO:0006405 31 27 0,000 0,02424859 0,03142411 ! mRNA catabolic process GO:0006402 31 27 0,000 0,02424859 0,03141295 ! myelination GO:0042552 31 27 0,000 0,02424859 0,0314018 ! trans-Golgi network GO:0005802 31 27 0,000 0,02424859 0,03139065 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,02424859 0,03137952 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,02424859 0,03136839 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,02424859 0,03135727 ! vasculogenesis GO:0001570 32 27 0,000 0,02424859 0,03134616 ! hexose transport GO:0008645 28 27 0,000 0,02424859 0,03133506 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,02424859 0,03132396 ! spindle organization GO:0007051 38 27 0,000 0,02424859 0,03131287 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,02424859 0,03130179 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,02424859 0,03129072 ! cell fate determination GO:0001709 29 27 0,000 0,02424859 0,03127965 ! lipid oxidation GO:0034440 29 27 0,000 0,02424859 0,0312686 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,02424859 0,03125755 ! collagen binding GO:0005518 29 27 0,000 0,02424859 0,03124651 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,02424859 0,03123547 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,02424859 0,03122445 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,02424859 0,03121343 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,02424859 0,03120242 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,02424859 0,03119142 ! membrane docking GO:0022406 29 27 0,000 0,02424859 0,03118042 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,02424859 0,03116944 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,02424859 0,03115846 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,02424859 0,03114749 ! phospholipid transport GO:0015914 29 27 0,000 0,02424859 0,03113652 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,02424859 0,03112557 ! aminopeptidase activity GO:0004177 33 27 0,000 0,02424859 0,03111462 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,02424859 0,03110368 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,02424859 0,03109275 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,02424859 0,03108182 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,02424859 0,0310709 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,02424859 0,03105999 ! Golgi stack GO:0005795 30 28 0,000 0,02513597 0,03218534 ! male gonad development GO:0008584 32 28 0,000 0,02513597 0,03217404 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,02513597 0,03216276 ! lipoprotein binding GO:0008034 31 28 0,000 0,02513597 0,03215148 ! mesoderm formation GO:0001707 34 28 0,000 0,02513597 0,03214021 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,02513597 0,03212895 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,02513597 0,0321177 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,02513597 0,03210645 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,02513597 0,03209521 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,02513597 0,03208398 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,02513597 0,03207276 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,02513597 0,03206155 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,02513597 0,03205034 ! DNA damage checkpoint GO:0000077 48 28 0,000 0,02513597 0,03203914 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,02513597 0,03202795 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,02513597 0,03201677 ! sister chromatid segregation GO:0000819 49 28 0,000 0,02513597 0,03200559 ! post-embryonic development GO:0009791 32 28 0,000 0,02513597 0,03199442 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,02513597 0,03198326 ! detection of visible light GO:0009584 30 28 0,000 0,02513597 0,03197211 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,02513597 0,03196097 ! receptor regulator activity GO:0030545 31 28 0,000 0,02513597 0,03194983 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,02513597 0,0319387 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,02513597 0,03192758 ! response to heat GO:0009408 33 28 0,000 0,02513597 0,03191647 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,02513597 0,03190537 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,02602259 0,03301927 ! hormone binding GO:0042562 31 29 0,000 0,02602259 0,03300779 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,02602259 0,03299632 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,02602259 0,03298485 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,02602259 0,0329734 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,02602259 0,03296195 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,02602259 0,03295051 ! ceramide metabolic process GO:0006672 29 29 0,000 0,02602259 0,03293907 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,02602259 0,03292765 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,02602259 0,03291623 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,02602259 0,03290482 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,02602259 0,03289342 ! regulation of pH GO:0006885 30 29 0,000 0,02602259 0,03288203 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,02602259 0,03287064 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,02602259 0,03285926 ! phospholipase C activity GO:0004629 43 29 0,000 0,02602259 0,03284789 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,02602259 0,03283653 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,02602259 0,03282518 ! sodium channel activity GO:0005272 33 29 0,000 0,02602259 0,03281383 ! sarcoplasm GO:0016528 31 29 0,000 0,02602259 0,03280249 ! detection of light stimulus GO:0009583 31 29 0,000 0,02602259 0,03279116 ! spermatid development GO:0007286 30 29 0,000 0,02602259 0,03277984 ! DNA polymerase activity GO:0034061 34 29 0,000 0,02602259 0,03276852 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,02602259 0,03275721 ! sarcolemma GO:0042383 30 29 0,000 0,02602259 0,03274592 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,02602259 0,03273462 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,02602259 0,03272334 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02602259 0,03271206 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,02690845 0,03381399 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,02690845 0,03380235 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,02690845 0,03379071 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,02690845 0,03377909 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,02690845 0,03376747 ! scavenger receptor activity GO:0005044 39 30 0,000 0,02690845 0,03375586 ! spliceosome assembly GO:0000245 34 30 0,000 0,02690845 0,03374425 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,02690845 0,03373266 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,02690845 0,03372107 ! glutamate receptor activity GO:0008066 35 30 0,000 0,02690845 0,03370949 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,02690845 0,03369791 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,02690845 0,03368635 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,02690845 0,03367479 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,02690845 0,03366325 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,02690845 0,03365171 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,02690845 0,03364017 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,02690845 0,03362865 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,02690845 0,03361713 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,02690845 0,03360562 ! protein-lipid complex GO:0032994 41 30 0,000 0,02690845 0,03359412 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,02690845 0,03358263 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,02690845 0,03357114 ! phosphatase binding GO:0019902 34 30 0,000 0,02690845 0,03355967 ! acute-phase response GO:0006953 44 30 0,000 0,02690845 0,0335482 ! segmentation GO:0035282 37 30 0,000 0,02690845 0,03353674 ! response to toxin GO:0009636 33 30 0,000 0,02690845 0,03352528 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02690845 0,03351384 ! antigen binding GO:0003823 33 30 0,000 0,02690845 0,0335024 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,02690845 0,03349097 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,02690845 0,03347955 ! ensheathment of neurons GO:0007272 35 30 0,000 0,02690845 0,03346813 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,02690845 0,03345672 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,02690845 0,03344532 ! vesicle localization GO:0051648 31 30 0,000 0,02690845 0,03343393 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,02779355 0,03452192 ! acrosomal vesicle GO:0001669 34 31 0,000 0,02779355 0,03451017 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02779355 0,03449843 ! protein targeting to membrane GO:0006612 35 31 0,000 0,02779355 0,03448669 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,02779355 0,03447497 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,02779355 0,03446325 ! formation of primary germ layer GO:0001704 37 31 0,000 0,02779355 0,03445154 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,02779355 0,03443984 ! endocytic vesicle GO:0030139 33 31 0,000 0,02779355 0,03442814 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,02779355 0,03441646 ! spermatid differentiation GO:0048515 32 31 0,000 0,02779355 0,03440478 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,02779355 0,03439311 ! neuron fate commitment GO:0048663 44 31 0,000 0,02779355 0,03438144 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,02779355 0,03436979 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,02779355 0,03435814 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,02779355 0,0343465 ! cell junction assembly GO:0034329 36 31 0,000 0,02779355 0,03433487 ! drug binding GO:0008144 34 31 0,000 0,02779355 0,03432325 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,02779355 0,03431163 ! peptide transport GO:0015833 36 31 0,000 0,02779355 0,03430003 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,02779355 0,03428843 ! peripheral nervous system development GO:0007422 35 31 0,000 0,02779355 0,03427684 ! I band GO:0031674 34 31 0,000 0,02779355 0,03426525 ! BMP signaling pathway GO:0030509 33 31 0,000 0,02779355 0,03425368 ! adult locomotory behavior GO:0008344 37 31 0,000 0,02779355 0,03424211 ! gene silencing GO:0016458 33 31 0,000 0,02779355 0,03423055 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,0286779 0,03530778 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,0286779 0,03529587 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,0286779 0,03528397 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,0286779 0,03527207 ! meiosis I GO:0007127 53 32 0,000 0,0286779 0,03526018 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,0286779 0,0352483 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,0286779 0,03523643 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,0286779 0,03522457 ! vesicle coat GO:0030120 39 32 0,000 0,0286779 0,03521271 ! cytokine production GO:0001816 32 32 0,000 0,0286779 0,03520086 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,0286779 0,03518902 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,0286779 0,03517719 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,0286779 0,03516537 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,0286779 0,03515355 ! oxygen binding GO:0019825 33 32 0,000 0,0286779 0,03514174 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,0286779 0,03512994 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,0286779 0,03511815 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,0286779 0,03510636 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,0286779 0,03509459 ! microtubule organizing center part GO:0044450 46 32 0,000 0,0286779 0,03508282 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,02956148 0,03615162 ! DNA helicase activity GO:0003678 55 33 0,000 0,02956148 0,03613951 ! neural tube development GO:0021915 37 33 0,000 0,02956148 0,0361274 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,02956148 0,0361153 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,02956148 0,03610321 ! organelle envelope lumen GO:0031970 46 33 0,000 0,02956148 0,03609113 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,02956148 0,03607905 ! NAD or NADH binding GO:0051287 36 33 0,000 0,02956148 0,03606699 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,02956148 0,03605493 ! B cell differentiation GO:0030183 37 33 0,000 0,02956148 0,03604288 ! aerobic respiration GO:0009060 35 33 0,000 0,02956148 0,03603084 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,02956148 0,0360188 ! tissue remodeling GO:0048771 37 33 0,000 0,02956148 0,03600678 ! flagellum GO:0019861 34 33 0,000 0,02956148 0,03599476 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,02956148 0,03598275 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,02956148 0,03597074 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,02956148 0,03595875 ! odontogenesis GO:0042476 39 34 0,000 0,03044431 0,03702029 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03044431 0,03700795 ! lipid homeostasis GO:0055088 37 34 0,000 0,03044431 0,03699562 ! telencephalon development GO:0021537 36 34 0,000 0,03044431 0,0369833 ! negative regulation of hydrolase activity GO:0051346 36 34 0,000 0,03044431 0,03697099 ! clathrin coat GO:0030118 41 34 0,000 0,03044431 0,03695869 ! cell growth GO:0016049 36 34 0,000 0,03044431 0,03694639 ! protein polymerization GO:0051258 38 34 0,000 0,03044431 0,03693411 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,03044431 0,03692183 ! learning GO:0007612 51 34 0,000 0,03044431 0,03690956 ! keratinization GO:0031424 40 34 0,000 0,03044431 0,03689729 ! ovulation cycle process GO:0022602 35 34 0,000 0,03044431 0,03688504 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,03044431 0,03687279 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,03044431 0,03686056 ! amino acid binding GO:0016597 40 34 0,000 0,03044431 0,03684833 ! regulation of protein stability GO:0031647 35 34 0,000 0,03044431 0,03683611 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,03044431 0,03682389 ! glycogen metabolic process GO:0005977 48 34 0,000 0,03044431 0,03681169 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,03044431 0,03679949 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,03044431 0,0367873 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03132639 0,03784062 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03132639 0,03782809 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03132639 0,03781557 ! MHC protein complex GO:0042611 50 35 0,000 0,03132639 0,03780307 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03132639 0,03779056 ! vesicle lumen GO:0031983 38 35 0,000 0,03132639 0,03777807 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,03132639 0,03776559 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03132639 0,03775311 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03132639 0,03774064 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03132639 0,03772818 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03132639 0,03771573 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03132639 0,03770329 ! ovulation cycle GO:0042698 37 35 0,000 0,03132639 0,03769085 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03132639 0,03767843 ! collagen GO:0005581 54 35 0,000 0,03132639 0,03766601 ! glucan metabolic process GO:0044042 49 35 0,000 0,03132639 0,0376536 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03132639 0,03764119 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03132639 0,0376288 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03132639 0,03761641 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03132639 0,03760404 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03132639 0,03759167 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03132639 0,0375793 ! polyol metabolic process GO:0019751 46 35 0,000 0,03132639 0,03756695 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,03132639 0,03755461 ! cytokinesis GO:0000910 38 35 0,000 0,03132639 0,03754227 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03132639 0,03752994 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03220771 0,03857312 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03220771 0,03856046 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03220771 0,03854781 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03220771 0,03853517 ! SMAD binding GO:0046332 39 36 0,000 0,03220771 0,03852253 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03220771 0,0385099 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03220771 0,03849729 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03220771 0,03848468 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03220771 0,03847208 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03220771 0,03845948 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03220771 0,0384469 ! nucleus organization GO:0006997 42 36 0,000 0,03220771 0,03843432 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,03220771 0,03842175 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03220771 0,03840919 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,03220771 0,03839664 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03220771 0,0383841 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03220771 0,03837156 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,03308827 0,03940778 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,03308827 0,03939491 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,03308827 0,03938206 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,03308827 0,03936922 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,03308827 0,03935638 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,03308827 0,03934355 ! endoribonuclease activity GO:0004521 48 37 0,000 0,03308827 0,03933073 ! hindbrain development GO:0030902 43 37 0,000 0,03308827 0,03931792 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,03308827 0,03930512 ! pigmentation GO:0043473 51 37 0,000 0,03308827 0,03929232 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,03308827 0,03927954 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,03308827 0,03926676 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,03308827 0,03925399 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,03308827 0,03924123 ! sensory perception of taste GO:0050909 37 37 0,000 0,03308827 0,03922848 ! cell junction organization GO:0034330 44 37 0,000 0,03308827 0,03921573 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,03308827 0,03920299 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,03308827 0,03919027 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,03308827 0,03917755 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,03308827 0,03916483 ! coated pit GO:0005905 44 37 0,000 0,03308827 0,03915213 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,03396808 0,04018015 ! regulation of translational initiation GO:0006446 50 38 0,000 0,03396808 0,04016712 ! organic ether metabolic process GO:0018904 50 38 0,000 0,03396808 0,0401541 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,03396808 0,0401411 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,03396808 0,0401281 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,03396808 0,04011511 ! hydro-lyase activity GO:0016836 44 38 0,000 0,03396808 0,04010213 ! synapse organization GO:0050808 43 38 0,000 0,03396808 0,04008915 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,03396808 0,04007619 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,03396808 0,04006323 ! organic anion transport GO:0015711 42 38 0,000 0,03396808 0,04005028 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,03396808 0,04003734 ! monosaccharide binding GO:0048029 41 38 0,000 0,03396808 0,04002441 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,03396808 0,04001148 ! phagocytosis GO:0006909 44 38 0,000 0,03396808 0,03999857 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,03396808 0,03998566 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,03396808 0,03997276 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,03396808 0,03995987 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,03396808 0,03994699 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,03396808 0,03993412 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,03396808 0,03992125 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,03396808 0,0399084 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,03484714 0,040928 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,03484714 0,04091483 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,03484714 0,04090166 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,03484714 0,04088851 ! T cell differentiation GO:0030217 64 39 0,000 0,03484714 0,04087536 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,03484714 0,04086222 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,03484714 0,04084909 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,03484714 0,04083597 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,03484714 0,04082285 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,03484714 0,04080975 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,03484714 0,04079665 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,03484714 0,04078356 ! amine receptor activity GO:0008227 48 39 0,000 0,03484714 0,04077048 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,03484714 0,04075741 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,03484714 0,04074435 ! double-strand break repair GO:0006302 70 39 0,000 0,03484714 0,04073129 ! pigment metabolic process GO:0042440 43 39 0,000 0,03484714 0,04071825 ! RNA modification GO:0009451 39 39 0,000 0,03484714 0,04070521 ! damaged DNA binding GO:0003684 51 40 0,000 0,03572544 0,0417178 ! peroxisomal membrane GO:0005778 44 40 0,000 0,03572544 0,04170445 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,03572544 0,04169111 ! positive regulation of cell development GO:0010720 43 40 0,000 0,03572544 0,04167778 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,03572544 0,04166446 ! biopolymer methylation GO:0043414 45 40 0,000 0,03572544 0,04165114 ! neuron migration GO:0001764 43 40 0,000 0,03572544 0,04163783 ! regulation of protein secretion GO:0050708 45 40 0,000 0,03572544 0,04162454 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,03572544 0,04161125 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,03572544 0,04159796 ! positive regulation of defense response GO:0031349 41 40 0,000 0,03572544 0,04158469 ! mammary gland development GO:0030879 47 40 0,000 0,03572544 0,04157143 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,03572544 0,04155817 ! neuropeptide binding GO:0042923 42 40 0,000 0,03572544 0,04154492 ! regulation of tube size GO:0035150 44 40 0,000 0,03572544 0,04153168 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,03572544 0,04151845 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,03572544 0,04150523 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,03572544 0,04149202 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,03572544 0,04147881 ! chromatin remodeling GO:0006338 44 40 0,000 0,03572544 0,04146561 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,03572544 0,04145242 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,036603 0,04245715 ! Notch signaling pathway GO:0007219 46 41 0,000 0,036603 0,04244365 ! keratin filament GO:0045095 44 41 0,000 0,036603 0,04243017 ! peptide metabolic process GO:0006518 42 41 0,000 0,036603 0,04241669 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,036603 0,04240322 ! late endosome membrane GO:0031902 45 41 0,000 0,036603 0,04238976 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,036603 0,0423763 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,036603 0,04236286 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,036603 0,04234942 ! lamellipodium GO:0030027 56 41 0,000 0,036603 0,042336 ! glycolysis GO:0006096 43 41 0,000 0,036603 0,04232258 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,036603 0,04230917 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,036603 0,04229576 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,0374798 0,04329522 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,0374798 0,04328151 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,0374798 0,04326782 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,0374798 0,04325413 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,0374798 0,04324045 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,0374798 0,04322678 ! nuclear export GO:0051168 46 42 0,000 0,0374798 0,04321312 ! developmental growth GO:0048589 45 42 0,000 0,0374798 0,04319946 ! structural constituent of muscle GO:0008307 46 42 0,000 0,0374798 0,04318582 ! mitochondrial transport GO:0006839 45 42 0,000 0,0374798 0,04317218 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,0374798 0,04315855 ! metal cluster binding GO:0051540 47 42 0,000 0,0374798 0,04314493 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,0374798 0,04313132 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,0374798 0,04311772 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,0374798 0,04310413 ! RNA catabolic process GO:0006401 49 43 0,000 0,03835585 0,04409774 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,03835585 0,04408384 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,03835585 0,04406996 ! positive regulation of growth GO:0045927 47 43 0,000 0,03835585 0,04405608 ! cell recognition GO:0008037 51 43 0,000 0,03835585 0,04404222 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,03835585 0,04402836 ! gliogenesis GO:0042063 46 43 0,000 0,03835585 0,04401451 ! endosome transport GO:0016197 48 43 0,000 0,03835585 0,04400067 ! striated muscle contraction GO:0006941 45 43 0,000 0,03835585 0,04398684 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,03835585 0,04397301 ! antioxidant activity GO:0016209 53 43 0,000 0,03835585 0,0439592 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,03835585 0,04394539 ! activation of caspase activity GO:0006919 60 43 0,000 0,03835585 0,04393159 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,03835585 0,0439178 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,03835585 0,04390402 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,03923114 0,04489185 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,03923114 0,04487777 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,03923114 0,0448637 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,03923114 0,04484964 ! chemokine activity GO:0008009 48 44 0,000 0,03923114 0,04483559 ! ruffle GO:0001726 50 44 0,000 0,03923114 0,04482155 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,03923114 0,04480752 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,03923114 0,04479349 ! cartilage development GO:0051216 48 44 0,000 0,03923114 0,04477948 ! membrane fusion GO:0006944 52 44 0,000 0,03923114 0,04476547 ! channel regulator activity GO:0016247 54 44 0,000 0,03923114 0,04475147 ! excretion GO:0007588 53 44 0,000 0,03923114 0,04473748 ! male sex differentiation GO:0046661 52 44 0,000 0,03923114 0,0447235 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,03923114 0,04470953 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,03923114 0,04469557 ! amino acid activation GO:0043038 45 44 0,000 0,03923114 0,04468161 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,03923114 0,04466767 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04010569 0,04564916 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04010569 0,04563492 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04010569 0,04562069 ! organellar ribosome GO:0000313 46 45 0,000 0,04010569 0,04560647 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,04010569 0,04559226 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04010569 0,04557806 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04010569 0,04556386 ! transport vesicle GO:0030133 53 45 0,000 0,04010569 0,04554968 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04010569 0,0455355 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04010569 0,04552133 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,04010569 0,04550717 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04010569 0,04549302 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04010569 0,04547888 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04010569 0,04546475 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04010569 0,04545063 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04010569 0,04543651 ! synaptosome GO:0019717 50 45 0,000 0,04010569 0,0454224 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04010569 0,04540831 ! regulation of action potential GO:0001508 56 46 0,000 0,04097949 0,04638324 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,04097949 0,04636885 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,04097949 0,04635448 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,04097949 0,04634011 ! methylation GO:0032259 51 46 0,000 0,04097949 0,04632575 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,04097949 0,0463114 ! regulation of ion transport GO:0043269 54 46 0,000 0,04097949 0,04629705 ! leukocyte migration GO:0050900 49 46 0,000 0,04097949 0,04628272 ! neuromuscular process GO:0050905 56 46 0,000 0,04097949 0,0462684 ! sulfotransferase activity GO:0008146 54 46 0,000 0,04097949 0,04625408 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,04097949 0,04623977 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,04185254 0,04721029 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,04185254 0,0471957 ! microtubule binding GO:0008017 61 47 0,000 0,04185254 0,04718111 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,04185254 0,04716654 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,04185254 0,04715197 ! RNA elongation GO:0006354 52 47 0,000 0,04185254 0,04713741 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,04185254 0,04712286 ! mRNA binding GO:0003729 65 47 0,000 0,04185254 0,04710832 ! response to insulin stimulus GO:0032868 57 47 0,000 0,04185254 0,04709379 ! axon GO:0030424 53 48 0,000 0,04272484 0,04806051 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,04272484 0,04804569 ! proteasome complex GO:0000502 50 48 0,000 0,04272484 0,04803089 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,04272484 0,04801609 ! protein homooligomerization GO:0051260 63 48 0,000 0,04272484 0,0480013 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,04272484 0,04798653 ! kinetochore GO:0000776 69 48 0,000 0,04272484 0,04797176 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,04272484 0,047957 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,04272484 0,04794224 ! growth factor receptor binding GO:0070851 58 48 0,000 0,04272484 0,0479275 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,04272484 0,04791277 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,04272484 0,04789804 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,04272484 0,04788333 ! B cell mediated immunity GO:0019724 53 48 0,000 0,04272484 0,04786862 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,04272484 0,04785393 ! regulation of cell shape GO:0008360 55 48 0,000 0,04272484 0,04783924 ! protein N-terminus binding GO:0047485 57 48 0,000 0,04272484 0,04782456 ! establishment of organelle localization GO:0051656 58 48 0,000 0,04272484 0,04780989 ! cell cortex part GO:0044448 54 48 0,000 0,04272484 0,04779523 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,0435964 0,04875526 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,0435964 0,04874032 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,0435964 0,04872539 ! response to temperature stimulus GO:0009266 57 49 0,000 0,0435964 0,04871046 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,0435964 0,04869555 ! lipid modification GO:0030258 55 49 0,000 0,0435964 0,04868065 ! synaptic vesicle GO:0008021 56 49 0,000 0,0435964 0,04866575 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,0435964 0,04865086 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,0435964 0,04863598 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,0435964 0,04862112 ! regulation of actin filament length GO:0030832 62 49 0,000 0,0435964 0,04860626 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,0435964 0,0485914 ! negative regulation of cytoskeleton organization GO:0051494 73 49 0,000 0,0435964 0,04857656 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,04446721 0,04953172 ! DNA damage response, signal transduction GO:0042770 84 50 0,000 0,04446721 0,0495166 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,04446721 0,04950149 ! glucose catabolic process GO:0006007 54 50 0,000 0,04446721 0,04948639 ! aging GO:0007568 92 50 0,000 0,04446721 0,04947129 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,04446721 0,04945621 ! heart morphogenesis GO:0003007 57 50 0,000 0,04446721 0,04944114 ! integrin binding GO:0005178 56 50 0,000 0,04446721 0,04942607 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,04446721 0,04941102 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,04533727 0,05036247 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,04533727 0,05034714 ! regulation of ossification GO:0030278 59 51 0,000 0,04533727 0,05033182 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,04533727 0,05031651 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,04533727 0,05030121 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,04533727 0,05028591 ! germ cell development GO:0007281 56 51 0,000 0,04533727 0,05027063 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,04620659 0,05121897 ! regulation of cellular component size GO:0032535 66 52 0,000 0,04620659 0,05120341 ! carbohydrate transport GO:0008643 57 52 0,000 0,04620659 0,05118786 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,04620659 0,05117232 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,04620659 0,05115679 ! cell maturation GO:0048469 68 52 0,000 0,04620659 0,05114127 ! vesicle organization GO:0016050 59 52 0,000 0,04620659 0,05112576 ! cell redox homeostasis GO:0045454 57 52 0,000 0,04620659 0,05111026 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,04620659 0,05109476 ! lipid transporter activity GO:0005319 58 52 0,000 0,04620659 0,05107928 ! cytokine receptor activity GO:0004896 54 52 0,000 0,04620659 0,05106381 ! antiporter activity GO:0015297 53 52 0,000 0,04620659 0,05104834 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,04707516 0,05199218 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,04707516 0,05197645 ! keratinocyte differentiation GO:0030216 60 53 0,000 0,04707516 0,05196072 ! basement membrane GO:0005604 55 53 0,000 0,04707516 0,051945 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,04707516 0,05192929 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,04707516 0,0519136 ! chloride transport GO:0006821 60 53 0,000 0,04707516 0,05189791 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,04707516 0,05188223 ! DNA catabolic process GO:0006308 57 53 0,000 0,04707516 0,05186656 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,04707516 0,0518509 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,04707516 0,05183525 ! single fertilization GO:0007338 58 53 0,000 0,04707516 0,05181961 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,04794298 0,05275898 GO:0010863|positive regulation of phospholipase C activity, ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,04794298 0,05274307 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,04794298 0,05272717 ! coated membrane GO:0048475 65 54 0,000 0,04794298 0,05271127 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,04794298 0,05269539 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,04794298 0,05267952 ! cellular defense response GO:0006968 61 54 0,000 0,04794298 0,05266366 ! gastrulation GO:0007369 62 54 0,000 0,04794298 0,05264781 ! dendrite GO:0030425 60 55 0,000 0,04881007 0,05358385 ! regulation of mitosis GO:0007088 79 55 0,000 0,04881007 0,05356773 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,04881007 0,05355162 ! respiratory chain GO:0070469 57 55 0,000 0,04881007 0,05353552 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,04881007 0,05351942 ! extracellular matrix organization GO:0030198 77 55 0,000 0,04881007 0,05350334 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,04881007 0,05348727 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,04881007 0,05347121 ! translation initiation factor activity GO:0003743 66 55 0,000 0,04881007 0,05345516 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,04881007 0,05343911 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,04967641 0,0543713 ! heat shock protein binding GO:0031072 62 56 0,000 0,04967641 0,05435499 ! late endosome GO:0005770 60 56 0,000 0,04967641 0,05433869 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,04967641 0,0543224 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,04967641 0,05430612 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,04967641 0,05428985 ! ribonuclease activity GO:0004540 67 56 0,000 0,04967641 0,05427359 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,04967641 0,05425735 ! mesoderm development GO:0007498 67 56 0,000 0,04967641 0,05424111 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,04967641 0,05422488 ! antigen processing and presentation GO:0019882 73 56 0,000 0,04967641 0,05420865 ! proton transport GO:0015992 59 56 0,000 0,04967641 0,05419244 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,050542 0,05512025 ! chromosome segregation GO:0007059 92 57 0,000 0,050542 0,05510378 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,050542 0,05508731 ! diacylglycerol binding GO:0019992 65 57 0,000 0,050542 0,05507086 ! B cell activation GO:0042113 63 57 0,000 0,050542 0,05505441 ! small ribosomal subunit GO:0015935 58 57 0,000 0,050542 0,05503798 ! detection of external stimulus GO:0009581 64 57 0,000 0,050542 0,05502156 ! occluding junction GO:0070160 75 58 0,000 0,05140686 0,05594637 GO:0005923|tight junction, ! epidermal cell differentiation GO:0009913 66 58 0,000 0,05140686 0,05592968 ! hydrogen transport GO:0006818 61 58 0,000 0,05140686 0,05591301 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 0,000 0,05140686 0,05589634 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,05140686 0,05587968 ! response to nutrient GO:0007584 68 58 0,000 0,05140686 0,05586304 ! large ribosomal subunit GO:0015934 64 58 0,000 0,05140686 0,0558464 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,05140686 0,05582978 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,05140686 0,05581316 ! myosin complex GO:0016459 64 58 0,000 0,05140686 0,05579656 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,05227097 0,05671758 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,05227097 0,05670072 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,05227097 0,05668386 ! actin filament organization GO:0007015 65 59 0,000 0,05227097 0,05666702 ! regulation of heart contraction GO:0008016 71 59 0,000 0,05227097 0,05665018 ! hexose catabolic process GO:0019320 64 59 0,000 0,05227097 0,05663336 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,05227097 0,05661654 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,05227097 0,05659974 ! cell projection assembly GO:0030031 79 59 0,000 0,05227097 0,05658294 ! appendage morphogenesis GO:0035107 68 59 0,000 0,05227097 0,05656615 GO:0035108|limb morphogenesis, ! fertilization GO:0009566 65 59 0,000 0,05227097 0,05654938 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,05227097 0,05653261 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,05227097 0,05651586 ! adult behavior GO:0030534 72 59 0,000 0,05227097 0,05649911 ! organelle localization GO:0051640 70 59 0,000 0,05227097 0,05648238 ! positive regulation of secretion GO:0051047 66 60 0,000 0,05313434 0,05739831 ! molecular adaptor activity GO:0060090 73 60 0,000 0,05313434 0,05738132 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,05313434 0,05736434 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,05313434 0,05734736 ! copper ion binding GO:0005507 85 60 0,000 0,05313434 0,0573304 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,05313434 0,05731345 ! activation of immune response GO:0002253 72 60 0,000 0,05313434 0,05729651 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,05313434 0,05727958 ! regulation of caspase activity GO:0043281 78 60 0,000 0,05313434 0,05726266 ! appendage development GO:0048736 69 60 0,000 0,05313434 0,05724574 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,05313434 0,05722884 ! secondary metabolic process GO:0019748 67 60 0,000 0,05313434 0,05721195 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,05399698 0,05812363 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,05399698 0,05810648 ! learning or memory GO:0007611 79 61 0,000 0,05399698 0,05808935 ! Ras GTPase binding GO:0017016 78 61 0,000 0,05399698 0,05807222 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,05399698 0,05805511 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,05485887 0,05896439 GO:0090046|regulation of transcription regulator activity, ! lysosomal membrane GO:0005765 69 62 0,000 0,05485887 0,05894703 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,05485887 0,05892967 ! nuclear pore GO:0005643 79 62 0,000 0,05485887 0,05891232 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,05485887 0,05889498 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,05485887 0,05887766 ! chloride channel activity GO:0005254 72 62 0,000 0,05485887 0,05886034 ! cell soma GO:0043025 68 62 0,000 0,05485887 0,05884303 ! microtubule motor activity GO:0003777 94 62 0,000 0,05485887 0,05882574 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,05485887 0,05880845 ! focal adhesion GO:0005925 72 62 0,000 0,05485887 0,05879117 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,05485887 0,05877391 ! FAD binding GO:0050660 71 63 0,000 0,05572002 0,05967899 ! regulation of endopeptidase activity GO:0052548 81 63 0,000 0,05572002 0,05966147 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,05572002 0,05964397 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,05572002 0,05962647 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,05572002 0,05960899 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,05572002 0,05959151 ! regulation of immune effector process GO:0002697 81 63 0,000 0,05572002 0,05957405 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,05658044 0,06047625 ! tRNA processing GO:0008033 73 64 0,000 0,05658044 0,06045853 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,05658044 0,06044083 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,05658044 0,06042314 ! adaptive immune response GO:0002250 70 64 0,000 0,05658044 0,06040545 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,05658044 0,06038778 ! neurotransmitter transport GO:0006836 72 64 0,000 0,05658044 0,06037012 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,05658044 0,06035247 ! lymphocyte differentiation GO:0030098 93 65 0,000 0,05744011 0,06125155 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,05744011 0,06123365 ! gonad development GO:0008406 71 65 0,000 0,05744011 0,06121576 ! protein import into nucleus GO:0006606 73 66 0,000 0,05829905 0,06211301 ! developmental maturation GO:0021700 85 66 0,000 0,05829905 0,06209488 ! tubulin binding GO:0015631 92 66 0,000 0,05829905 0,06207675 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,05829905 0,06205864 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,05829905 0,06204053 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,05829905 0,06202244 ! regulation of peptidase activity GO:0052547 86 67 0,000 0,05915726 0,06291711 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,05915726 0,06289877 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,05915726 0,06288044 ! nuclear import GO:0051170 74 67 0,000 0,05915726 0,06286212 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,05915726 0,06284382 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,05915726 0,06282552 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,05915726 0,06280724 ! chloride ion binding GO:0031404 79 67 0,000 0,05915726 0,06278897 ! humoral immune response GO:0006959 75 67 0,000 0,05915726 0,0627707 ! amine binding GO:0043176 77 67 0,000 0,05915726 0,06275245 ! extrinsic to membrane GO:0019898 75 67 0,000 0,05915726 0,06273421 ! anion channel activity GO:0005253 77 67 0,000 0,05915726 0,06271598 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,05915726 0,06269776 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,06001472 0,06358807 ! amine catabolic process GO:0009310 73 68 0,000 0,06001472 0,0635696 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,06001472 0,06355115 ! cell-substrate junction GO:0030055 78 68 0,000 0,06001472 0,06353271 ! mRNA transport GO:0051028 88 69 0,000 0,06087145 0,06442097 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,06087145 0,06440228 ! small GTPase binding GO:0031267 86 69 0,000 0,06087145 0,06438361 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,06087145 0,06436495 ! sarcomere GO:0030017 74 69 0,000 0,06087145 0,0643463 ! exocytosis GO:0006887 76 69 0,000 0,06087145 0,06432766 ! nucleosome assembly GO:0006334 87 69 0,000 0,06087145 0,06430903 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,06087145 0,06429041 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,06087145 0,0642718 ! amine biosynthetic process GO:0009309 78 70 0,000 0,06172745 0,06515675 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,06172745 0,06513791 ! early endosome GO:0005769 104 70 0,000 0,06172745 0,06511907 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,06172745 0,06510024 ! regulation of lipase activity GO:0060191 78 70 0,000 0,06172745 0,06508143 ! amino acid transport GO:0006865 76 70 0,000 0,06172745 0,06506262 ! chromatin assembly GO:0031497 88 70 0,000 0,06172745 0,06504383 ! calcium channel activity GO:0005262 86 70 0,000 0,06172745 0,06502505 ! axon guidance GO:0007411 87 70 0,000 0,06172745 0,06500628 ! cell cortex GO:0005938 77 70 0,000 0,06172745 0,06498752 ! nuclear chromosome part GO:0044454 94 70 0,000 0,06172745 0,06496877 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,06258271 0,06584994 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,06258271 0,06583095 ! protein localization in nucleus GO:0034504 78 71 0,000 0,06258271 0,06581197 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,06258271 0,06579301 ! pore complex GO:0046930 89 72 0,000 0,06343724 0,06667216 ! response to hypoxia GO:0001666 84 72 0,000 0,06343724 0,06665295 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,06343724 0,06663376 ! regulation of lyase activity GO:0051339 85 72 0,000 0,06343724 0,06661458 ! acute inflammatory response GO:0002526 91 72 0,000 0,06343724 0,06659541 ! apical junction complex GO:0043296 90 72 0,000 0,06343724 0,06657625 ! phospholipase activity GO:0004620 99 72 0,000 0,06343724 0,06655711 ! membrane raft GO:0045121 81 72 0,000 0,06343724 0,06653797 ! regulation of neurological system process GO:0031644 91 72 0,000 0,06343724 0,06651884 ! structural constituent of cytoskeleton GO:0005200 78 72 0,000 0,06343724 0,06649973 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,06429104 0,06737538 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,06429104 0,06735603 ! protein transporter activity GO:0008565 80 73 0,000 0,06429104 0,06733669 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,06429104 0,06731736 ! exopeptidase activity GO:0008238 81 73 0,000 0,06429104 0,06729805 ! digestion GO:0007586 81 73 0,000 0,06429104 0,06727874 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,06429104 0,06725945 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,0651441 0,06813236 ! response to oxygen levels GO:0070482 86 74 0,000 0,0651441 0,06811283 ! potassium channel complex GO:0034705 84 74 0,000 0,0651441 0,06809332 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,0651441 0,06807381 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,0651441 0,06805432 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,0651441 0,06803483 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,0651441 0,06801536 ! blood coagulation GO:0007596 90 74 0,000 0,0651441 0,0679959 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,0651441 0,06797645 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,0651441 0,06795701 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,0651441 0,06793758 ! cell projection part GO:0044463 80 74 0,000 0,0651441 0,06791817 ! meiosis GO:0007126 108 75 0,000 0,06599643 0,06878713 GO:0051327|M phase of meiotic cell cycle, ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,06599643 0,06876749 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,06599643 0,06874785 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,06599643 0,06872822 ! regulation of blood pressure GO:0008217 82 75 0,000 0,06599643 0,06870861 ! transcription initiation GO:0006352 84 75 0,000 0,06599643 0,06868901 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,06599643 0,06866942 ! neuropeptide signaling pathway GO:0007218 85 76 0,000 0,06684803 0,06953567 ! defense response to bacterium GO:0042742 81 76 0,000 0,06684803 0,06951585 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,06684803 0,06949604 ! cell leading edge GO:0031252 97 76 0,000 0,06684803 0,06947624 ! meiotic cell cycle GO:0051321 109 76 0,000 0,06684803 0,06945645 ! condensed chromosome GO:0000793 106 76 0,000 0,06684803 0,06943668 ! protein-DNA complex GO:0032993 93 76 0,000 0,06684803 0,06941691 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,06684803 0,06939716 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,06684803 0,06937741 ! cytosolic ribosome GO:0022626 82 76 0,000 0,06684803 0,06935768 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,06684803 0,06933796 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,0676989 0,07020056 ! alcohol catabolic process GO:0046164 84 77 0,000 0,0676989 0,07018061 ! vacuolar membrane GO:0005774 86 77 0,000 0,0676989 0,07016067 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,0676989 0,07014075 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,0676989 0,07012083 ! establishment of RNA localization GO:0051236 97 77 0,000 0,0676989 0,07010093 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,0676989 0,07008104 ! protein oligomerization GO:0051259 93 77 0,000 0,0676989 0,07006115 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,06854903 0,07092084 ! endonuclease activity GO:0004519 111 78 0,000 0,06854903 0,07090073 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,06854903 0,07088063 ! inorganic anion transport GO:0015698 87 78 0,000 0,06854903 0,07086055 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,06854903 0,07084047 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,06854903 0,07082041 ! carboxylesterase activity GO:0004091 93 78 0,000 0,06854903 0,07080036 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,06854903 0,07078032 ! contractile fiber part GO:0044449 83 78 0,000 0,06854903 0,07076029 ! RNA localization GO:0006403 99 79 0,000 0,06939844 0,07161684 ! vitamin metabolic process GO:0006766 86 79 0,000 0,06939844 0,07159658 ! T cell activation GO:0042110 120 79 0,000 0,06939844 0,07157634 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,06939844 0,07155611 ! phosphoinositide binding GO:0035091 99 79 0,000 0,06939844 0,07153589 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,07024712 0,07239025 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,07024712 0,07236981 ! rhythmic process GO:0048511 90 80 0,000 0,07024712 0,07234938 ! SH3 domain binding GO:0017124 95 80 0,000 0,07024712 0,07232896 ! hemostasis GO:0007599 96 80 0,000 0,07024712 0,07230855 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,07024712 0,07228815 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,07024712 0,07226777 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,07024712 0,07224739 ! rRNA processing GO:0006364 84 80 0,000 0,07024712 0,07222703 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,07109507 0,07307828 ! vacuolar part GO:0044437 91 81 0,000 0,07109507 0,0730577 ! mitochondrion organization GO:0007005 104 82 0,000 0,07194229 0,07390749 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,07194229 0,07388668 ! forebrain development GO:0030900 93 82 0,000 0,07194229 0,07386588 ! external side of plasma membrane GO:0009897 105 82 0,000 0,07194229 0,0738451 ! cellular respiration GO:0045333 85 82 0,000 0,07194229 0,07382433 ! heparin binding GO:0008201 108 82 0,000 0,07194229 0,07380357 ! microtubule-based movement GO:0007018 119 83 0,000 0,07278879 0,07465097 ! nuclear speck GO:0016607 99 83 0,000 0,07278879 0,07462999 ! rRNA metabolic process GO:0016072 88 83 0,000 0,07278879 0,07460902 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,07278879 0,07458806 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,07278879 0,07456712 ! regulation of T cell activation GO:0050863 104 83 0,000 0,07278879 0,07454618 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,07278879 0,07452526 ! contractile fiber GO:0043292 88 83 0,000 0,07278879 0,07450435 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,07278879 0,07448345 ! regulation of membrane potential GO:0042391 98 83 0,000 0,07278879 0,07446256 ! cilium GO:0005929 88 83 0,000 0,07278879 0,07444169 ! regulation of defense response GO:0031347 98 84 0,000 0,07363456 0,07528556 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,07363456 0,07526446 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,07363456 0,07524338 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,0744796 0,07608557 ! monooxygenase activity GO:0004497 92 85 0,000 0,0744796 0,07606427 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,0744796 0,07604298 ! protein binding, bridging GO:0030674 104 85 0,000 0,0744796 0,07602171 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,07532392 0,076862 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,07532392 0,07684051 ! lipase activity GO:0016298 114 86 0,000 0,07532392 0,07681902 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,07532392 0,07679755 ! adherens junction GO:0005912 100 86 0,000 0,07532392 0,0767761 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,07616751 0,07761427 ! leukocyte differentiation GO:0002521 118 87 0,000 0,07616751 0,07759259 ! pigment granule GO:0048770 101 87 0,000 0,07616751 0,07757093 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,07616751 0,07754928 ! organelle outer membrane GO:0031968 102 88 0,000 0,07701038 0,07838556 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,07701038 0,0783637 ! growth factor binding GO:0019838 102 88 0,000 0,07701038 0,07834184 ! protein processing GO:0016485 100 88 0,000 0,07701038 0,07832 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,07785252 0,0791544 ! ATP metabolic process GO:0046034 100 90 0,000 0,07869394 0,0799876 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,07869394 0,07996532 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,07869394 0,07994305 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,07869394 0,0799208 ! sterol metabolic process GO:0016125 102 90 0,000 0,07869394 0,07989855 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,07869394 0,07987632 ! anion binding GO:0043168 104 90 0,000 0,07869394 0,0798541 ! amine transport GO:0015837 97 90 0,000 0,07869394 0,0798319 ! response to virus GO:0009615 109 90 0,000 0,07869394 0,0798097 ! outer membrane GO:0019867 104 90 0,000 0,07869394 0,07978752 ! extracellular matrix part GO:0044420 111 90 0,000 0,07869394 0,07976535 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,07953464 0,0805951 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,07953464 0,08057272 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,07953464 0,08055035 ! sulfur metabolic process GO:0006790 98 91 0,000 0,07953464 0,08052799 ! sex differentiation GO:0007548 103 91 0,000 0,07953464 0,08050565 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,07953464 0,08048332 ! hormone metabolic process GO:0042445 107 91 0,000 0,07953464 0,080461 ! detection of stimulus GO:0051606 100 91 0,000 0,07953464 0,08043869 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,08037462 0,08126569 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,08037462 0,08124317 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,08037462 0,08122066 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,08037462 0,08119817 ! extracellular structure organization GO:0043062 119 92 0,000 0,08037462 0,08117569 ! protein import GO:0017038 102 93 0,000 0,08121387 0,08200061 ! regulation of cytoskeleton organization GO:0051493 133 93 0,000 0,08121387 0,08197792 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,08121387 0,08195524 ! response to nutrient levels GO:0031667 105 93 0,000 0,08121387 0,08193258 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,08121387 0,08190992 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,0820524 0,08273277 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,0820524 0,08270991 ! anchoring junction GO:0070161 108 94 0,000 0,0820524 0,08268706 ! neurotransmitter binding GO:0042165 105 94 0,000 0,0820524 0,08266423 ! DNA packaging GO:0006323 113 94 0,000 0,0820524 0,0826414 ! homophilic cell adhesion GO:0007156 107 95 0,000 0,08289022 0,08346219 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,08289022 0,08343916 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,08289022 0,08341614 ! protein localization in organelle GO:0033365 104 95 0,000 0,08289022 0,08339314 ! immune effector process GO:0002252 110 95 0,000 0,08289022 0,08337014 ! apical plasma membrane GO:0016324 105 95 0,000 0,08289022 0,08334716 ! translational elongation GO:0006414 104 96 0,000 0,08372731 0,08416567 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,08372731 0,08414249 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,08372731 0,08411931 ! receptor complex GO:0043235 131 96 0,000 0,08372731 0,08409615 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,08372731 0,084073 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,08372731 0,08404987 ! electron transport chain GO:0022900 104 97 0,000 0,08456368 0,08486611 ! microtubule associated complex GO:0005875 135 97 0,000 0,08456368 0,08484277 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,08456368 0,08481944 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,08456368 0,08479613 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,08456368 0,08477283 ! carboxylic acid binding GO:0031406 108 97 0,000 0,08456368 0,08474954 ! protein maturation GO:0051604 109 97 0,000 0,08456368 0,08472626 ! intermediate filament GO:0005882 102 98 0,000 0,08539934 0,08554003 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,08539934 0,08551655 ! hormone activity GO:0005179 113 99 0,000 0,08623428 0,08632894 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,08623428 0,08630525 ! unfolded protein binding GO:0051082 118 100 0,000 0,0870685 0,08711626 ! nuclear chromosome GO:0000228 127 100 0,000 0,0870685 0,08709237 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,0870685 0,0870685