pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/10456-0-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 9,923E-06 0,01828869 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 1,518E-05 0,01399039 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 2,137E-05 0,01313057 ! positive regulation of cell growth GO:0030307 6 6 1,000 2,276E-05 0,01048567 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,276E-05 8,389E-03 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 2,276E-05 6,99E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 2,276E-05 5,992E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 3,184E-05 7,335E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,184E-05 6,52E-03 ! regulation of stress fiber formation GO:0051492 9 8 1,000 4,242E-05 7,819E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 4,242E-05 7,108E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 5,451E-05 8,371E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 5,451E-05 7,728E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 5,451E-05 7,176E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 5,451E-05 6,697E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 6,809E-05 7,843E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 6,809E-05 7,382E-03 ! skin development GO:0043588 11 11 1,000 8,316E-05 8,515E-03 ! regulation of viral genome replication GO:0045069 11 11 1,000 8,316E-05 8,067E-03 ! apoptotic nuclear changes GO:0030262 11 11 1,000 8,316E-05 7,663E-03 ! negative regulation of signal transduction GO:0009968 71 71 2,000 8,463E-05 7,427E-03 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 9,973E-05 8,354E-03 ! negative regulation of translation GO:0017148 12 12 1,000 9,973E-05 7,991E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 1,038E-04 7,967E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 1,178E-04 8,683E-03 ! regulation of viral reproduction GO:0050792 13 13 1,000 1,178E-04 8,349E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 1,178E-04 8,04E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,178E-04 7,752E-03 GO:0001952|regulation of cell-matrix adhesion, ! chromosome condensation GO:0030261 15 15 1,000 1,583E-04 0,01006243 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,048E-04 0,01258171 ! meiosis I GO:0007127 18 18 1,000 2,302E-04 0,01368853 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,302E-04 0,01326076 ! nucleus organization GO:0006997 20 20 1,000 2,855E-04 0,01594692 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,154E-04 0,01709554 ! RNA export from nucleus GO:0006405 22 22 1,000 3,467E-04 0,0182554 ! spindle organization GO:0007051 22 22 1,000 3,467E-04 0,01774831 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 3,467E-04 0,01726862 ! positive regulation of growth GO:0045927 23 23 1,000 3,794E-04 0,01840304 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 4,864E-04 0,02298722 ! response to insulin stimulus GO:0032868 28 26 1,000 4,864E-04 0,02241254 ! keratinocyte differentiation GO:0030216 28 28 1,000 5,65E-04 0,0253972 ! epidermal cell differentiation GO:0009913 31 31 1,000 6,936E-04 0,03043664 ! nuclear export GO:0051168 32 32 1,000 7,394E-04 0,0316892 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 8,351E-04 0,03497988 ! meiosis GO:0007126 37 37 1,000 9,894E-04 0,04052144 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 9,894E-04 0,03964054 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 9,894E-04 0,03879712 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 9,894E-04 0,03798885 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,044E-03 0,03925431 ! chromosome segregation GO:0007059 38 38 1,000 1,044E-03 0,03846922 ! meiotic cell cycle GO:0051321 38 38 1,000 1,044E-03 0,03771493 ! negative regulation of transferase activity GO:0051348 40 40 1,000 1,156E-03 0,04098541 ! regulation of caspase activity GO:0043281 41 41 1,000 1,215E-03 0,04224556 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 1,215E-03 0,04146323 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 1,275E-03 0,04271579 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 1,275E-03 0,04195301 ! mitochondrion organization GO:0007005 44 43 1,000 1,336E-03 0,04319822 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 1,399E-03 0,04444481 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 1,463E-03 0,04569262 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 1,463E-03 0,04493107 ! regulation of actin filament-based process GO:0032970 47 46 1,000 1,528E-03 0,04617196 ! regulation of peptidase activity GO:0052547 46 46 1,000 1,528E-03 0,04542725 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 1,528E-03 0,04470618 ! positive regulation of ligase activity GO:0051351 47 46 1,000 1,528E-03 0,04400765 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 1,663E-03 0,04715996 ! regulation of ligase activity GO:0051340 50 49 1,000 1,733E-03 0,04838892 ! RNA transport GO:0050658 50 50 1,000 1,804E-03 0,04961909 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! RNA localization GO:0006403 52 52 1,000 1,95E-03 0,05284841 ! regulation of GTPase activity GO:0043087 53 52 1,000 1,95E-03 0,05208249 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 2,025E-03 0,05331548 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 2,179E-03 0,0565692 ! regulation of cell adhesion GO:0030155 56 55 1,000 2,179E-03 0,05578352 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 2,589E-03 0,06535617 ! cellular respiration GO:0045333 62 61 1,000 2,675E-03 0,06661322 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 2,675E-03 0,06572504 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 2,762E-03 0,06697671 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 2,94E-03 0,07038098 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 3,032E-03 0,07163563 ! DNA packaging GO:0006323 66 66 1,000 3,124E-03 0,07288956 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 3,124E-03 0,07197844 ! regulation of cell size GO:0008361 68 68 1,000 3,314E-03 0,07539515 ! regulation of translation GO:0006417 69 69 1,000 3,41E-03 0,07664673 ! ribosome biogenesis GO:0042254 71 71 1,000 3,607E-03 0,08010089 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 3,708E-03 0,08135334 ! regulation of protein modification process GO:0031399 79 78 1,000 4,339E-03 0,09407163 ! nuclear transport GO:0051169 79 79 1,000 4,448E-03 0,09532795 GO:0006913|nucleocytoplasmic transport, ! heart development GO:0007507 90 87 1,000 5,372E-03 0,11379757 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 5,739E-03 0,1201983 ! negative regulation of cell cycle GO:0045786 92 91 1,000 5,864E-03 0,12143588 ! DNA replication GO:0006260 91 91 1,000 5,864E-03 0,12008659 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 5,99E-03 0,12132369 ! epidermis development GO:0008544 94 94 1,000 6,247E-03 0,12513823 ! regulation of cell growth GO:0001558 97 96 1,000 6,508E-03 0,12896983 ! rRNA transcription GO:0009303 5 5 0,000 6,526E-03 0,12794145 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 6,526E-03 0,1265947 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 6,526E-03 0,12527601 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 6,526E-03 0,1239845 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 6,526E-03 0,12271935 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 6,526E-03 0,12147976 ! reproductive cellular process GO:0048610 5 5 0,000 6,526E-03 0,12026497 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 6,526E-03 0,11907422 ! negative regulation of blood pressure GO:0045776 6 5 0,000 6,526E-03 0,11790683 ! prostate gland development GO:0030850 5 5 0,000 6,526E-03 0,1167621 ! metencephalon development GO:0022037 5 5 0,000 6,526E-03 0,11563939 ! water transport GO:0006833 5 5 0,000 6,526E-03 0,11453806 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 6,526E-03 0,11345751 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 6,526E-03 0,11239716 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 6,526E-03 0,11135645 ! glycerol metabolic process GO:0006071 5 5 0,000 6,526E-03 0,11033483 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 6,526E-03 0,10933179 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 6,526E-03 0,10834682 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 6,526E-03 0,10737943 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 6,526E-03 0,10642917 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 6,526E-03 0,10549558 ! filopodium assembly GO:0046847 7 5 0,000 6,526E-03 0,10457823 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 6,526E-03 0,10367669 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 6,526E-03 0,10279057 ! GTP metabolic process GO:0046039 5 5 0,000 6,526E-03 0,10191946 ! establishment of tissue polarity GO:0007164 5 5 0,000 6,526E-03 0,101063 ! mRNA stabilization GO:0048255 5 5 0,000 6,526E-03 0,1002208 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 6,526E-03 0,09939253 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 6,526E-03 0,09857784 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 6,526E-03 0,09777639 ! social behavior GO:0035176 5 5 0,000 6,526E-03 0,09698788 ! macrophage chemotaxis GO:0048246 6 5 0,000 6,526E-03 0,09621197 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 6,526E-03 0,09544839 ! memory GO:0007613 5 5 0,000 6,526E-03 0,09469682 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 6,526E-03 0,093957 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 6,526E-03 0,09322866 ! membrane hyperpolarization GO:0060081 5 5 0,000 6,526E-03 0,09251151 ! response to lipid GO:0033993 5 5 0,000 6,526E-03 0,09180532 ! erythrocyte maturation GO:0043249 5 5 0,000 6,526E-03 0,09110982 ! hippocampus development GO:0021766 6 5 0,000 6,526E-03 0,09042479 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 6,526E-03 0,08974997 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 6,526E-03 0,08908516 ! middle ear morphogenesis GO:0042474 5 5 0,000 6,526E-03 0,08843012 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 6,526E-03 0,08778465 ! mechanosensory behavior GO:0007638 5 5 0,000 6,526E-03 0,08714853 ! heart looping GO:0001947 5 5 0,000 6,526E-03 0,08652156 ! negative regulation of endocytosis GO:0045806 5 5 0,000 6,526E-03 0,08590355 ! response to interferon-gamma GO:0034341 5 5 0,000 6,526E-03 0,0852943 ! pseudouridine synthesis GO:0001522 5 5 0,000 6,526E-03 0,08469364 ! endocrine pancreas development GO:0031018 5 5 0,000 6,526E-03 0,08410137 ! pH reduction GO:0045851 5 5 0,000 6,526E-03 0,08351734 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 6,526E-03 0,08294136 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 6,526E-03 0,08237326 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 6,526E-03 0,0818129 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 6,526E-03 0,08126011 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 6,526E-03 0,08071474 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 6,526E-03 0,08017664 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 6,526E-03 0,07964567 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 6,526E-03 0,07912169 ! adrenal gland development GO:0030325 5 5 0,000 6,526E-03 0,07860455 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 6,526E-03 0,07809413 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 6,526E-03 0,0775903 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 6,526E-03 0,07709293 ! astrocyte differentiation GO:0048708 5 5 0,000 6,526E-03 0,07660189 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 6,526E-03 0,07611707 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 6,526E-03 0,07563834 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 6,526E-03 0,0751656 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 6,526E-03 0,07469874 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 6,526E-03 0,07423763 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 6,526E-03 0,07378219 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 6,526E-03 0,0733323 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 6,526E-03 0,07288786 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 6,526E-03 0,07244877 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 6,526E-03 0,07201495 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 6,526E-03 0,07158629 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 6,526E-03 0,0711627 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 6,526E-03 0,0707441 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 6,526E-03 0,07033039 ! response to ATP GO:0033198 5 5 0,000 6,526E-03 0,06992149 ! regulation of type I interferon production GO:0032479 5 5 0,000 6,526E-03 0,06951732 ! regulation of appetite GO:0032098 5 5 0,000 6,526E-03 0,0691178 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 6,526E-03 0,06872284 ! paraxial mesoderm development GO:0048339 5 5 0,000 6,526E-03 0,06833237 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 6,526E-03 0,06794631 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 6,526E-03 0,06756459 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 6,526E-03 0,06718713 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,526E-03 0,06681387 ! receptor clustering GO:0043113 5 5 0,000 6,526E-03 0,06644473 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 6,526E-03 0,06607965 ! fear response GO:0042596 5 5 0,000 6,526E-03 0,06571856 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 6,526E-03 0,06536139 ! lens development in camera-type eye GO:0002088 5 5 0,000 6,526E-03 0,06500809 ! retinol metabolic process GO:0042572 5 5 0,000 6,526E-03 0,06465858 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 6,526E-03 0,06431282 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 6,526E-03 0,06397073 ! positive regulation of exocytosis GO:0045921 6 5 0,000 6,526E-03 0,06363226 ! parturition GO:0007567 5 5 0,000 6,526E-03 0,06329735 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,526E-03 0,06296595 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 6,526E-03 0,062638 ! Schwann cell differentiation GO:0014037 5 5 0,000 6,526E-03 0,06231345 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 6,526E-03 0,06199225 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 6,526E-03 0,06167434 ! protein heterooligomerization GO:0051291 5 5 0,000 6,526E-03 0,06135968 ! regulation of gliogenesis GO:0014013 5 5 0,000 6,526E-03 0,06104821 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 6,526E-03 0,06073988 ! response to UV-B GO:0010224 5 5 0,000 6,526E-03 0,06043466 ! oligodendrocyte development GO:0014003 5 5 0,000 6,526E-03 0,06013248 ! hyaluronan metabolic process GO:0030212 5 5 0,000 6,526E-03 0,05983332 ! activated T cell proliferation GO:0050798 5 5 0,000 6,526E-03 0,05953711 ! interaction with symbiont GO:0051702 5 5 0,000 6,526E-03 0,05924383 ! cellular extravasation GO:0045123 5 5 0,000 6,526E-03 0,05895341 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 6,526E-03 0,05866584 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 6,526E-03 0,05838105 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 6,526E-03 0,05809902 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 6,526E-03 0,05781969 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 6,526E-03 0,05754305 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 6,526E-03 0,05726903 ! response to amine stimulus GO:0014075 5 5 0,000 6,526E-03 0,05699761 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 6,526E-03 0,05672876 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 6,526E-03 0,05646243 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 6,526E-03 0,05619858 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 6,526E-03 0,05593719 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 6,526E-03 0,05567822 ! neuron recognition GO:0008038 5 5 0,000 6,526E-03 0,05542164 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 6,526E-03 0,05516742 ! decidualization GO:0046697 5 5 0,000 6,526E-03 0,05491551 ! hair follicle maturation GO:0048820 5 5 0,000 6,526E-03 0,05466589 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 6,526E-03 0,05441854 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 6,526E-03 0,05417341 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 6,526E-03 0,05393048 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 6,526E-03 0,05368972 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 6,526E-03 0,0534511 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 6,526E-03 0,05321459 ! postreplication repair GO:0006301 5 5 0,000 6,526E-03 0,05298016 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 6,526E-03 0,05274779 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 6,526E-03 0,05251745 ! histone methylation GO:0016571 5 5 0,000 6,526E-03 0,05228912 ! DNA methylation GO:0006306 5 5 0,000 6,526E-03 0,05206276 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,526E-03 0,05183835 ! T cell lineage commitment GO:0002360 5 5 0,000 6,526E-03 0,05161586 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 6,526E-03 0,05139528 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 6,526E-03 0,05117658 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 6,526E-03 0,05095973 ! intracellular cholesterol transport GO:0032367 5 5 0,000 6,526E-03 0,05074471 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 6,526E-03 0,0505315 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 6,526E-03 0,05032007 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 6,526E-03 0,0501104 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 6,526E-03 0,04990248 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 6,526E-03 0,04969627 ! sterol catabolic process GO:0016127 5 5 0,000 6,526E-03 0,04949176 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 6,526E-03 0,04928892 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 6,526E-03 0,04908774 ! detection of biotic stimulus GO:0009595 5 5 0,000 6,526E-03 0,0488882 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 6,526E-03 0,04869027 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 6,526E-03 0,04849394 ! zymogen activation GO:0031638 5 5 0,000 6,526E-03 0,04829918 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 6,526E-03 0,04810599 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 6,526E-03 0,04791433 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 6,526E-03 0,04772419 ! peptidyl-lysine modification GO:0018205 5 5 0,000 6,526E-03 0,04753556 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 6,526E-03 0,04734841 ! peptidyl-histidine modification GO:0018202 5 5 0,000 6,526E-03 0,04716273 ! nucleosome positioning GO:0016584 5 5 0,000 6,526E-03 0,0469785 ! regulation of isotype switching GO:0045191 5 5 0,000 6,526E-03 0,04679571 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 6,526E-03 0,04661433 ! negative regulation of neurological system process GO:0031645 5 5 0,000 6,526E-03 0,04643435 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 6,526E-03 0,04625576 ! glutathione biosynthetic process GO:0006750 5 5 0,000 6,526E-03 0,04607853 ! NADPH regeneration GO:0006740 5 5 0,000 6,526E-03 0,04590266 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 6,526E-03 0,04572812 ! positive regulation of epidermis development GO:0045684 5 5 0,000 6,526E-03 0,04555491 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 6,526E-03 0,04538301 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 6,526E-03 0,04521239 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 6,526E-03 0,04504306 ! sarcomere organization GO:0045214 5 5 0,000 6,526E-03 0,04487499 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 6,526E-03 0,04470817 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 6,526E-03 0,04454258 ! negative regulation of glucose transport GO:0010829 5 5 0,000 6,526E-03 0,04437822 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 6,526E-03 0,04421506 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 6,526E-03 0,0440531 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 6,526E-03 0,04389232 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 6,526E-03 0,04373271 ! spleen development GO:0048536 5 5 0,000 6,526E-03 0,04357426 ! male genitalia development GO:0030539 5 5 0,000 6,526E-03 0,04341695 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 6,526E-03 0,04326078 ! quaternary ammonium group transport GO:0015697 5 5 0,000 6,526E-03 0,04310572 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 6,526E-03 0,04295177 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 6,526E-03 0,04279892 ! removal of superoxide radicals GO:0019430 6 5 0,000 6,526E-03 0,04264715 ! myeloid cell homeostasis GO:0002262 5 5 0,000 6,526E-03 0,04249645 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 6,526E-03 0,04234682 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 6,526E-03 0,04219823 ! ATP catabolic process GO:0006200 5 5 0,000 6,526E-03 0,04205069 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 6,526E-03 0,04190417 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 6,526E-03 0,04175867 ! blastocyst formation GO:0001825 5 5 0,000 6,526E-03 0,04161417 ! regulation of fibrinolysis GO:0051917 5 5 0,000 6,526E-03 0,04147068 ! embryonic gut development GO:0048566 5 5 0,000 6,526E-03 0,04132817 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 6,526E-03 0,04118663 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 6,526E-03 0,04104606 ! activation of innate immune response GO:0002218 5 5 0,000 6,526E-03 0,04090645 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 6,526E-03 0,04076778 ! catecholamine transport GO:0051937 5 5 0,000 6,526E-03 0,04063006 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 6,526E-03 0,04049325 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 6,526E-03 0,04035737 ! muscle adaptation GO:0043500 5 5 0,000 6,526E-03 0,0402224 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 6,526E-03 0,04008832 ! embryonic heart tube development GO:0035050 5 5 0,000 6,526E-03 0,03995514 ! cardiac cell differentiation GO:0035051 6 5 0,000 6,526E-03 0,03982284 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 6,526E-03 0,03969141 ! defense response to fungus GO:0050832 5 5 0,000 6,526E-03 0,03956084 ! lysogeny GO:0030069 5 5 0,000 6,526E-03 0,03943114 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 6,526E-03 0,03930228 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 6,526E-03 0,03917426 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 6,526E-03 0,03904707 ! response to nicotine GO:0035094 5 5 0,000 6,526E-03 0,0389207 ! establishment of cell polarity GO:0030010 5 5 0,000 6,526E-03 0,03879515 ! mitochondrion localization GO:0051646 5 5 0,000 6,526E-03 0,03867041 ! nucleus localization GO:0051647 5 5 0,000 6,526E-03 0,03854646 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 6,526E-03 0,03842331 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 6,774E-03 0,03976066 ! anti-apoptosis GO:0006916 100 99 1,000 6,909E-03 0,04042414 ! ectoderm development GO:0007398 99 99 1,000 6,909E-03 0,04029621 ! response to hormone stimulus GO:0009725 102 100 1,000 7,045E-03 0,040961 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 7,826E-03 0,04535663 ! axon extension GO:0048675 7 6 0,000 7,826E-03 0,04521444 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 7,826E-03 0,04507315 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 7,826E-03 0,04493273 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 7,826E-03 0,04479319 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 7,826E-03 0,04465451 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 7,826E-03 0,04451669 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 7,826E-03 0,04437971 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 7,826E-03 0,04424358 ! virus-host interaction GO:0019048 6 6 0,000 7,826E-03 0,04410828 ! regulation of S phase GO:0033261 6 6 0,000 7,826E-03 0,0439738 ! myotube differentiation GO:0014902 6 6 0,000 7,826E-03 0,04384014 ! regulation of B cell proliferation GO:0030888 6 6 0,000 7,826E-03 0,04370729 ! bone remodeling GO:0046849 6 6 0,000 7,826E-03 0,04357525 ! N-glycan processing GO:0006491 6 6 0,000 7,826E-03 0,043444 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 7,826E-03 0,04331354 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 7,826E-03 0,04318385 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 7,826E-03 0,04305495 ! retina development in camera-type eye GO:0060041 6 6 0,000 7,826E-03 0,04292681 ! RNA methylation GO:0001510 6 6 0,000 7,826E-03 0,04279943 ! cartilage condensation GO:0001502 7 6 0,000 7,826E-03 0,0426728 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 7,826E-03 0,04254692 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 7,826E-03 0,04242179 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 7,826E-03 0,04229738 ! artery development GO:0060840 6 6 0,000 7,826E-03 0,04217371 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 7,826E-03 0,04205075 ! bile acid metabolic process GO:0008206 6 6 0,000 7,826E-03 0,04192851 ! androgen metabolic process GO:0008209 6 6 0,000 7,826E-03 0,04180698 ! estrogen metabolic process GO:0008210 6 6 0,000 7,826E-03 0,04168615 ! limbic system development GO:0021761 7 6 0,000 7,826E-03 0,04156602 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 7,826E-03 0,04144657 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 7,826E-03 0,04132781 ! positive regulation of heart contraction GO:0045823 6 6 0,000 7,826E-03 0,04120974 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 7,826E-03 0,04109233 ! pathogenesis GO:0009405 6 6 0,000 7,826E-03 0,04097559 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 7,826E-03 0,04085951 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 7,826E-03 0,04074409 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 7,826E-03 0,04062932 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 7,826E-03 0,04051519 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 7,826E-03 0,0404017 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 7,826E-03 0,04028885 ! arginine metabolic process GO:0006525 6 6 0,000 7,826E-03 0,04017662 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 7,826E-03 0,04006502 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 7,826E-03 0,03995404 ! glutamate catabolic process GO:0006538 7 6 0,000 7,826E-03 0,03984367 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 7,826E-03 0,0397339 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 7,826E-03 0,03962475 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 7,826E-03 0,03951618 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 7,826E-03 0,03940822 ! ER overload response GO:0006983 6 6 0,000 7,826E-03 0,03930084 ! V(D)J recombination GO:0033151 6 6 0,000 7,826E-03 0,03919404 ! focal adhesion formation GO:0048041 7 6 0,000 7,826E-03 0,03908782 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 7,826E-03 0,03898218 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 7,826E-03 0,03887711 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 7,826E-03 0,0387726 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 7,826E-03 0,03866865 ! regulation of heart rate GO:0002027 6 6 0,000 7,826E-03 0,03856526 ! lipid digestion GO:0044241 6 6 0,000 7,826E-03 0,03846242 ! asymmetric protein localization GO:0008105 6 6 0,000 7,826E-03 0,03836013 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 7,826E-03 0,03825837 ! phagocytosis, engulfment GO:0006911 6 6 0,000 7,826E-03 0,03815716 ! Rac protein signal transduction GO:0016601 6 6 0,000 7,826E-03 0,03805648 ! regulation of vascular permeability GO:0043114 6 6 0,000 7,826E-03 0,03795633 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 7,826E-03 0,03785671 ! ruffle organization GO:0031529 6 6 0,000 7,826E-03 0,03775761 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 7,826E-03 0,03765903 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 7,826E-03 0,03756096 ! retinoic acid metabolic process GO:0042573 6 6 0,000 7,826E-03 0,0374634 ! neutral amino acid transport GO:0015804 6 6 0,000 7,826E-03 0,03736634 ! L-amino acid transport GO:0015807 6 6 0,000 7,826E-03 0,03726979 ! bone mineralization GO:0030282 6 6 0,000 7,826E-03 0,03717373 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 7,826E-03 0,03707817 ! negative regulation of ossification GO:0030279 6 6 0,000 7,826E-03 0,0369831 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 7,826E-03 0,03688851 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 7,826E-03 0,03679441 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 7,826E-03 0,03670078 ! purine base biosynthetic process GO:0009113 6 6 0,000 7,826E-03 0,03660763 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 7,826E-03 0,03651496 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 7,826E-03 0,03642275 ! regulation of phagocytosis GO:0050764 6 6 0,000 7,826E-03 0,036331 ! regulation of organ growth GO:0046620 6 6 0,000 7,826E-03 0,03623972 ! regulation of circadian rhythm GO:0042752 6 6 0,000 7,826E-03 0,03614889 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 7,826E-03 0,03605852 ! response to dsRNA GO:0043331 6 6 0,000 7,826E-03 0,0359686 ! DNA unwinding during replication GO:0006268 6 6 0,000 7,826E-03 0,03587912 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 7,826E-03 0,03579009 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 7,826E-03 0,0357015 ! genitalia development GO:0048806 6 6 0,000 7,826E-03 0,03561335 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 7,826E-03 0,03552563 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 7,826E-03 0,03543835 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 7,826E-03 0,03535149 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 7,826E-03 0,03526505 ! multicellular organismal aging GO:0010259 6 6 0,000 7,826E-03 0,03517904 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 7,826E-03 0,03509345 ! erythrocyte development GO:0048821 6 6 0,000 7,826E-03 0,03500827 ! renal water homeostasis GO:0003091 6 6 0,000 7,826E-03 0,0349235 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 7,826E-03 0,03483915 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 7,826E-03 0,0347552 ! ribosome assembly GO:0042255 6 6 0,000 7,826E-03 0,03467165 ! diencephalon development GO:0021536 6 6 0,000 7,826E-03 0,03458851 ! fucose catabolic process GO:0019317 6 6 0,000 7,826E-03 0,03450576 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 7,826E-03 0,03442341 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 7,826E-03 0,03434145 ! regulation of lipid transport GO:0032368 6 6 0,000 7,826E-03 0,03425987 ! regulation of cell division GO:0051302 6 6 0,000 7,826E-03 0,03417869 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 7,826E-03 0,03409789 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 7,826E-03 0,03401747 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 7,826E-03 0,03393743 ! salivary gland morphogenesis GO:0007435 6 6 0,000 7,826E-03 0,03385776 ! neuroblast proliferation GO:0007405 6 6 0,000 7,826E-03 0,03377847 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 7,826E-03 0,03369955 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 7,826E-03 0,033621 ! regulation of glucose transport GO:0010827 6 6 0,000 7,826E-03 0,03354281 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 7,826E-03 0,03346498 ! methionine biosynthetic process GO:0009086 6 6 0,000 7,826E-03 0,03338752 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 7,826E-03 0,03331041 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 7,826E-03 0,03323366 ! thymus development GO:0048538 6 6 0,000 7,826E-03 0,03315726 ! lymph node development GO:0048535 6 6 0,000 7,826E-03 0,03308121 ! organic cation transport GO:0015695 6 6 0,000 7,826E-03 0,03300551 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 7,826E-03 0,03293015 ! regulation of RNA splicing GO:0043484 6 6 0,000 7,826E-03 0,03285514 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 7,826E-03 0,03278047 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 7,826E-03 0,03270614 ! sperm-egg recognition GO:0035036 7 6 0,000 7,826E-03 0,03263214 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 7,826E-03 0,03255848 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 7,826E-03 0,03248515 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 7,826E-03 0,03241215 ! alditol metabolic process GO:0019400 6 6 0,000 7,826E-03 0,03233948 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 7,826E-03 0,03226713 ! regulation of amino acid transport GO:0051955 6 6 0,000 7,826E-03 0,03219511 ! maternal placenta development GO:0001893 6 6 0,000 7,826E-03 0,0321234 ! regulation of embryonic development GO:0045995 6 6 0,000 7,826E-03 0,03205202 ! negative regulation of immune effector process GO:0002698 6 6 0,000 7,826E-03 0,03198095 ! localization within membrane GO:0051668 6 6 0,000 7,826E-03 0,03191019 ! respiratory burst GO:0045730 7 7 0,000 9,125E-03 0,03712479 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 9,125E-03 0,03704301 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 9,125E-03 0,0369616 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 9,125E-03 0,03688055 ! positive regulation of blood pressure GO:0045777 7 7 0,000 9,125E-03 0,03679984 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 9,125E-03 0,03671949 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 9,125E-03 0,0366395 ! regulation of chemokine production GO:0032642 7 7 0,000 9,125E-03 0,03655984 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 9,125E-03 0,03648054 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 9,125E-03 0,03640158 ! cellular protein complex disassembly GO:0043624 8 7 0,000 9,125E-03 0,03632296 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 9,125E-03 0,03624467 ! gene silencing by RNA GO:0031047 7 7 0,000 9,125E-03 0,03616673 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 9,125E-03 0,03608912 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 9,125E-03 0,03601184 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 9,125E-03 0,03593489 ! axis specification GO:0009798 7 7 0,000 9,125E-03 0,03585827 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 9,125E-03 0,03578198 ! visual behavior GO:0007632 7 7 0,000 9,125E-03 0,03570601 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 9,125E-03 0,03563036 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 9,125E-03 0,03555503 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 9,125E-03 0,03548002 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 9,125E-03 0,03540532 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 9,125E-03 0,03533094 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 9,125E-03 0,03525687 ! endothelial cell differentiation GO:0045446 7 7 0,000 9,125E-03 0,03518311 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 9,125E-03 0,03510966 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 9,125E-03 0,03503652 ! digestive system development GO:0055123 7 7 0,000 9,125E-03 0,03496368 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 9,125E-03 0,03489114 ! regulation of exit from mitosis GO:0007096 7 7 0,000 9,125E-03 0,0348189 ! protein targeting to ER GO:0045047 8 7 0,000 9,125E-03 0,03474696 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 9,125E-03 0,03467532 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 9,125E-03 0,03460397 ! endoderm development GO:0007492 7 7 0,000 9,125E-03 0,03453291 ! regulation of defense response to virus GO:0050688 7 7 0,000 9,125E-03 0,03446215 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 9,125E-03 0,03439167 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 9,125E-03 0,03432149 ! response to hexose stimulus GO:0009746 7 7 0,000 9,125E-03 0,03425159 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 9,125E-03 0,03418197 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 9,125E-03 0,03411263 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 9,125E-03 0,03404358 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 9,125E-03 0,03397481 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 9,125E-03 0,03390631 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 9,125E-03 0,03383809 ! complement activation, alternative pathway GO:0006957 7 7 0,000 9,125E-03 0,03377014 ! arachidonic acid secretion GO:0050482 7 7 0,000 9,125E-03 0,03370246 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 9,125E-03 0,03363506 ! response to X-ray GO:0010165 7 7 0,000 9,125E-03 0,03356792 ! regulation of intracellular pH GO:0051453 7 7 0,000 9,125E-03 0,03350105 ! UV protection GO:0009650 7 7 0,000 9,125E-03 0,03343445 ! DNA integration GO:0015074 7 7 0,000 9,125E-03 0,03336811 ! myofibril assembly GO:0030239 7 7 0,000 9,125E-03 0,03330204 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 9,125E-03 0,03323622 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 9,125E-03 0,03317067 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 9,125E-03 0,03310537 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 9,125E-03 0,03304033 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 9,125E-03 0,03297555 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 9,125E-03 0,03291101 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 9,125E-03 0,03284674 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 9,125E-03 0,03278271 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 9,125E-03 0,03271893 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 9,125E-03 0,0326554 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 9,125E-03 0,03259211 ! axon cargo transport GO:0008088 7 7 0,000 9,125E-03 0,03252907 ! eating behavior GO:0042755 7 7 0,000 9,125E-03 0,03246627 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 9,125E-03 0,03240372 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 9,125E-03 0,0323414 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 9,125E-03 0,03227933 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 9,125E-03 0,03221749 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 9,125E-03 0,03215589 ! cranial nerve development GO:0021545 7 7 0,000 9,125E-03 0,03209452 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 9,125E-03 0,03203339 ! induction of an organ GO:0001759 7 7 0,000 9,125E-03 0,03197249 ! leukocyte activation during immune response GO:0002366 7 7 0,000 9,125E-03 0,03191182 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 9,125E-03 0,03185138 ! autonomic nervous system development GO:0048483 7 7 0,000 9,125E-03 0,03179117 ! intracellular lipid transport GO:0032365 7 7 0,000 9,125E-03 0,03173119 ! detection of chemical stimulus GO:0009593 8 7 0,000 9,125E-03 0,03167143 ! platelet activation GO:0030168 8 7 0,000 9,125E-03 0,0316119 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 9,125E-03 0,03155259 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 9,125E-03 0,0314935 ! natural killer cell activation GO:0030101 7 7 0,000 9,125E-03 0,03143463 ! response to gamma radiation GO:0010332 8 7 0,000 9,125E-03 0,03137599 ! NADP metabolic process GO:0006739 7 7 0,000 9,125E-03 0,03131756 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 9,125E-03 0,03125935 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 9,125E-03 0,03120135 ! ubiquinone metabolic process GO:0006743 7 7 0,000 9,125E-03 0,03114357 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 9,125E-03 0,031086 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 9,125E-03 0,03102865 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 9,125E-03 0,03097151 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 9,125E-03 0,03091457 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 9,125E-03 0,03085785 ! regulation of ATPase activity GO:0043462 7 7 0,000 9,125E-03 0,03080133 ! cell-cell recognition GO:0009988 8 7 0,000 9,125E-03 0,03074502 ! hormone catabolic process GO:0042447 7 7 0,000 9,125E-03 0,03068892 ! dopamine metabolic process GO:0042417 7 7 0,000 9,125E-03 0,03063302 ! cAMP biosynthetic process GO:0006171 7 7 0,000 9,125E-03 0,03057732 ! oxygen transport GO:0015671 7 7 0,000 9,125E-03 0,03052183 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 9,125E-03 0,03046654 ! regulation of mRNA stability GO:0043488 7 7 0,000 9,125E-03 0,03041144 ! biogenic amine catabolic process GO:0042402 7 7 0,000 9,125E-03 0,03035655 ! regulation of axon extension GO:0030516 7 7 0,000 9,125E-03 0,03030185 ! cell killing GO:0001906 7 7 0,000 9,125E-03 0,03024735 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 9,125E-03 0,03019305 ! adult feeding behavior GO:0008343 7 7 0,000 9,125E-03 0,03013894 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 9,125E-03 0,03008502 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 9,125E-03 0,0300313 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 9,125E-03 0,02997777 ! negative regulation of T cell activation GO:0050868 7 7 0,000 9,125E-03 0,02992443 ! response to cold GO:0009409 7 7 0,000 9,125E-03 0,02987128 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01042261 0,03405827 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01042261 0,03399799 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01042261 0,03393792 ! positive regulation of translation GO:0045727 8 8 0,000 0,01042261 0,03387807 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01042261 0,03381842 ! superoxide anion generation GO:0042554 8 8 0,000 0,01042261 0,03375899 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01042261 0,03369976 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01042261 0,03364074 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01042261 0,03358193 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01042261 0,03352332 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01042261 0,03346492 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01042261 0,03340672 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01042261 0,03334872 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01042261 0,03329092 ! zinc ion transport GO:0006829 8 8 0,000 0,01042261 0,03323333 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01042261 0,03317593 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01042261 0,03311873 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01042261 0,03306173 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01042261 0,03300492 ! lipid localization GO:0010876 8 8 0,000 0,01042261 0,03294831 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01042261 0,03289189 ! response to cAMP GO:0051591 8 8 0,000 0,01042261 0,03283566 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01042261 0,03277963 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01042261 0,03272379 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01042261 0,03266813 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01042261 0,03261267 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01042261 0,0325574 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01042261 0,03250231 ! sensory perception of taste GO:0050909 8 8 0,000 0,01042261 0,0324474 ! organelle fusion GO:0048284 8 8 0,000 0,01042261 0,03239269 ! pancreas development GO:0031016 8 8 0,000 0,01042261 0,03233815 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01042261 0,0322838 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01042261 0,03222964 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01042261 0,03217565 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01042261 0,03212184 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01042261 0,03206822 ! sperm motility GO:0030317 8 8 0,000 0,01042261 0,03201477 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01042261 0,0319615 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01042261 0,03190841 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01042261 0,03185549 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01042261 0,03180275 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01042261 0,03175019 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01042261 0,03169779 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01042261 0,03164557 ! Golgi organization GO:0007030 8 8 0,000 0,01042261 0,03159352 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01042261 0,03154165 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01042261 0,03148994 ! fructose metabolic process GO:0006000 8 8 0,000 0,01042261 0,0314384 ! mannose metabolic process GO:0006013 9 8 0,000 0,01042261 0,03138703 ! NAD metabolic process GO:0019674 8 8 0,000 0,01042261 0,03133583 ! sex determination GO:0007530 8 8 0,000 0,01042261 0,03128479 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01042261 0,03123392 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01042261 0,03118322 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01042261 0,03113268 ! response to fungus GO:0009620 8 8 0,000 0,01042261 0,0310823 ! stem cell differentiation GO:0048863 8 8 0,000 0,01042261 0,03103209 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01042261 0,03098204 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01042261 0,03093215 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01042261 0,03088242 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01042261 0,03083285 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01042261 0,03078343 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01042261 0,03073418 ! vasoconstriction GO:0042310 8 8 0,000 0,01042261 0,03068508 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01042261 0,03063615 ! muscle cell development GO:0055001 8 8 0,000 0,01042261 0,03058736 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01042261 0,03053873 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01042261 0,03049026 ! sensory perception of pain GO:0019233 8 8 0,000 0,01042261 0,03044194 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01042261 0,03039377 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01042261 0,03034576 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01042261 0,03029789 ! chromatin silencing GO:0006342 8 8 0,000 0,01042261 0,03025018 ! tissue regeneration GO:0042246 8 8 0,000 0,01042261 0,03020261 ! salivary gland development GO:0007431 8 8 0,000 0,01042261 0,0301552 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01042261 0,03010794 ! T cell homeostasis GO:0043029 8 8 0,000 0,01042261 0,03006082 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01042261 0,03001385 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01042261 0,02996703 ! water homeostasis GO:0030104 8 8 0,000 0,01042261 0,02992035 ! cofactor transport GO:0051181 8 8 0,000 0,01042261 0,02987382 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01042261 0,02982743 ! acid secretion GO:0046717 8 8 0,000 0,01042261 0,02978118 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01042261 0,02973508 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01042261 0,02968912 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01042261 0,02964331 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01042261 0,02959763 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01042261 0,0295521 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01042261 0,0295067 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01042261 0,02946145 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01042261 0,02941633 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01042261 0,02937135 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01042261 0,02932651 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01042261 0,0292818 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01042261 0,02923723 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01042261 0,0291928 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01042261 0,0291485 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01042261 0,02910434 ! developmental induction GO:0031128 8 8 0,000 0,01042261 0,02906031 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01042261 0,02901641 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01042261 0,02897264 ! actin filament polymerization GO:0030041 9 8 0,000 0,01042261 0,02892901 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01042261 0,02888551 ! peptide hormone processing GO:0016486 8 8 0,000 0,01042261 0,02884214 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01042261 0,0287989 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01042261 0,02875578 ! lactation GO:0007595 10 9 0,000 0,01171862 0,03228313 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01171862 0,03223495 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01171862 0,03218691 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01171862 0,03213901 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01171862 0,03209125 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01171862 0,03204364 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01171862 0,03199617 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01171862 0,03194884 ! viral genome replication GO:0019079 9 9 0,000 0,01171862 0,03190165 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01171862 0,03185459 ! copper ion transport GO:0006825 9 9 0,000 0,01171862 0,03180768 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01171862 0,0317609 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01171862 0,03171426 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01171862 0,03166776 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01171862 0,0316214 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01171862 0,03157517 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01171862 0,03152907 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01171862 0,03148311 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01171862 0,03143728 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01171862 0,03139159 ! phospholipid efflux GO:0033700 9 9 0,000 0,01171862 0,03134603 ! response to alkaloid GO:0043279 10 9 0,000 0,01171862 0,0313006 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01171862 0,0312553 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01171862 0,03121014 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01171862 0,0311651 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01171862 0,03112019 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01171862 0,03107542 ! response to ethanol GO:0045471 9 9 0,000 0,01171862 0,03103077 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01171862 0,03098625 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01171862 0,03094185 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01171862 0,03089759 ! methionine metabolic process GO:0006555 9 9 0,000 0,01171862 0,03085345 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01171862 0,03080943 ! cerebral cortex development GO:0021987 9 9 0,000 0,01171862 0,03076555 ! response to osmotic stress GO:0006970 9 9 0,000 0,01171862 0,03072178 ! pigmentation during development GO:0048066 9 9 0,000 0,01171862 0,03067814 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01171862 0,03063463 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01171862 0,03059124 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01171862 0,03054797 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01171862 0,03050482 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01171862 0,0304618 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01171862 0,03041889 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01171862 0,03037611 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01171862 0,03033345 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01171862 0,0302909 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01171862 0,03024848 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01171862 0,03020617 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01171862 0,03016399 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01171862 0,03012192 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01171862 0,03007996 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01171862 0,03003813 ! DNA replication initiation GO:0006270 9 9 0,000 0,01171862 0,02999641 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01171862 0,0299548 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01171862 0,02991332 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01171862 0,02987194 ! histone acetylation GO:0016573 9 9 0,000 0,01171862 0,02983068 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01171862 0,02978954 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01171862 0,0297485 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01171862 0,02970758 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01171862 0,02966678 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01171862 0,02962608 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01171862 0,0295855 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01171862 0,02954503 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01171862 0,02950466 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01171862 0,02946441 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01171862 0,02942427 ! collagen catabolic process GO:0030574 9 9 0,000 0,01171862 0,02938424 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01171862 0,02934431 ! purine base metabolic process GO:0006144 9 9 0,000 0,01171862 0,0293045 ! gas transport GO:0015669 9 9 0,000 0,01171862 0,02926479 ! cholesterol efflux GO:0033344 9 9 0,000 0,01171862 0,02922519 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01171862 0,02918569 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01171862 0,02914631 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01171862 0,02910703 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01171862 0,02906785 ! defense response to virus GO:0051607 9 9 0,000 0,01171862 0,02902878 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01171862 0,02898982 ! actin filament-based movement GO:0030048 9 9 0,000 0,01171862 0,02895096 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01171862 0,0289122 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01301312 0,03206308 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01301312 0,03202027 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01301312 0,03197758 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01301312 0,031935 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01301312 0,03189253 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01301312 0,03185018 ! neuron maturation GO:0042551 10 10 0,000 0,01301312 0,03180794 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01301312 0,03176581 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01301312 0,03172379 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01301312 0,03168188 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01301312 0,03164008 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01301312 0,0315984 ! hormone secretion GO:0046879 10 10 0,000 0,01301312 0,03155682 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01301312 0,03151535 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01301312 0,03147399 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01301312 0,03143274 ! inositol metabolic process GO:0006020 10 10 0,000 0,01301312 0,0313916 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01301312 0,03135057 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01301312 0,03130964 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01301312 0,03126882 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01301312 0,0312281 ! glial cell development GO:0021782 10 10 0,000 0,01301312 0,03118749 ! phototransduction GO:0007602 11 10 0,000 0,01301312 0,03114699 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01301312 0,03110659 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01301312 0,0310663 ! fat cell differentiation GO:0045444 10 10 0,000 0,01301312 0,03102611 ! myoblast differentiation GO:0045445 10 10 0,000 0,01301312 0,03098603 ! centrosome cycle GO:0007098 10 10 0,000 0,01301312 0,03094604 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01301312 0,03090616 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01301312 0,03086639 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01301312 0,03082671 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01301312 0,03078714 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01301312 0,03074767 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01301312 0,0307083 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01301312 0,03066903 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01301312 0,03062986 ! plasma membrane organization GO:0007009 10 10 0,000 0,01301312 0,0305908 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01301312 0,03055183 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01301312 0,03051296 ! lysosomal transport GO:0007041 10 10 0,000 0,01301312 0,03047418 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01301312 0,03043551 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01301312 0,03039694 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01301312 0,03035846 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01301312 0,03032008 ! exocrine system development GO:0035272 10 10 0,000 0,01301312 0,0302818 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01301312 0,03024361 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01301312 0,03020552 ! embryo implantation GO:0007566 11 10 0,000 0,01301312 0,03016753 ! regulation of protein binding GO:0043393 11 10 0,000 0,01301312 0,03012963 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01301312 0,03009182 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01301312 0,03005411 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01301312 0,0300165 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01301312 0,02997898 ! protein export from nucleus GO:0006611 10 10 0,000 0,01301312 0,02994155 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01301312 0,02990422 ! cytolysis GO:0019835 10 10 0,000 0,01301312 0,02986698 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01301312 0,02982983 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01301312 0,02979277 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01301312 0,02975581 ! histone deacetylation GO:0016575 10 10 0,000 0,01301312 0,02971894 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01301312 0,02968216 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01301312 0,02964547 ! gland morphogenesis GO:0022612 10 10 0,000 0,01301312 0,02960887 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01301312 0,02957236 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01301312 0,02953594 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01301312 0,02949961 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01301312 0,02946337 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01301312 0,02942722 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01301312 0,02939116 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01301312 0,02935518 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01301312 0,0293193 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01301312 0,0292835 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01301312 0,02924778 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01301312 0,02921216 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01301312 0,02917662 ! nerve development GO:0021675 10 10 0,000 0,01301312 0,02914117 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01301312 0,02910581 ! gut development GO:0048565 10 10 0,000 0,01301312 0,02907053 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01301312 0,02903533 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01301312 0,02900022 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01301312 0,0289652 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01301312 0,02893026 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01301312 0,0288954 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01301312 0,02886063 ! protein stabilization GO:0050821 10 10 0,000 0,01301312 0,02882594 ! protein secretion GO:0009306 11 11 0,000 0,01430612 0,03165207 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01430612 0,03161412 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01430612 0,03157626 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01430612 0,03153849 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01430612 0,03150081 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01430612 0,03146322 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01430612 0,03142571 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01430612 0,0313883 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01430612 0,03135098 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01430612 0,03131375 ! signal complex assembly GO:0007172 11 11 0,000 0,01430612 0,0312766 ! microtubule-based transport GO:0010970 11 11 0,000 0,01430612 0,03123954 ! endothelial cell migration GO:0043542 11 11 0,000 0,01430612 0,03120257 ! peroxisomal transport GO:0043574 11 11 0,000 0,01430612 0,03116569 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01430612 0,0311289 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01430612 0,03109219 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01430612 0,03105557 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01430612 0,03101903 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01430612 0,03098258 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01430612 0,03094621 ! T cell proliferation GO:0042098 11 11 0,000 0,01430612 0,03090994 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01430612 0,03087374 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01430612 0,03083763 ! spinal cord development GO:0021510 11 11 0,000 0,01430612 0,03080161 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01430612 0,03076566 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01430612 0,03072981 ! cellular response to starvation GO:0009267 11 11 0,000 0,01430612 0,03069403 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01430612 0,03065834 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01430612 0,03062274 ! digestive system process GO:0022600 11 11 0,000 0,01430612 0,03058721 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01430612 0,03055177 ! fucose metabolic process GO:0006004 11 11 0,000 0,01430612 0,03051641 ! membrane budding GO:0006900 11 11 0,000 0,01430612 0,03048113 ! monoamine transport GO:0015844 11 11 0,000 0,01430612 0,03044593 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01430612 0,03041081 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01430612 0,03037578 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01430612 0,03034082 ! body fluid secretion GO:0007589 11 11 0,000 0,01430612 0,03030595 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01430612 0,03027115 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01430612 0,03023644 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01430612 0,0302018 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01430612 0,03016725 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01430612 0,03013277 ! membrane depolarization GO:0051899 11 11 0,000 0,01430612 0,03009837 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01430612 0,03006405 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01430612 0,03002981 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01430612 0,02999565 ! oogenesis GO:0048477 11 11 0,000 0,01430612 0,02996156 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01430612 0,02992755 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01430612 0,02989362 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01430612 0,02985977 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01430612 0,02982599 ! muscle maintenance GO:0046716 12 11 0,000 0,01430612 0,02979229 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01430612 0,02975866 ! hindbrain development GO:0030902 11 11 0,000 0,01430612 0,02972511 ! steroid catabolic process GO:0006706 11 11 0,000 0,01430612 0,02969164 ! endocrine process GO:0050886 11 11 0,000 0,01430612 0,02965824 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01430612 0,02962492 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01430612 0,02959167 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01430612 0,02955849 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01430612 0,02952539 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01430612 0,02949237 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01559761 0,03211887 ! translational initiation GO:0006413 12 12 0,000 0,01559761 0,03208303 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01559761 0,03204726 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01559761 0,03201157 ! initiation of viral infection GO:0019059 12 12 0,000 0,01559761 0,03197596 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01559761 0,03194043 ! iron ion transport GO:0006826 13 12 0,000 0,01559761 0,03190498 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01559761 0,03186961 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01559761 0,03183432 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01559761 0,03179911 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01559761 0,03176397 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01559761 0,03172891 ! collagen metabolic process GO:0032963 12 12 0,000 0,01559761 0,03169393 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01559761 0,03165902 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01559761 0,03162419 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01559761 0,03158944 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01559761 0,03155477 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01559761 0,03152017 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01559761 0,03148564 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,01559761 0,03145119 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01559761 0,03141682 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01559761 0,03138252 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01559761 0,0313483 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01559761 0,03131415 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01559761 0,03128008 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01559761 0,03124608 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01559761 0,03121215 ! acute-phase response GO:0006953 12 12 0,000 0,01559761 0,0311783 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01559761 0,03114452 ! vacuolar transport GO:0007034 12 12 0,000 0,01559761 0,03111081 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01559761 0,03107718 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01559761 0,03104362 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01559761 0,03101013 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01559761 0,03097671 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01559761 0,03094337 ! male gonad development GO:0008584 12 12 0,000 0,01559761 0,0309101 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01559761 0,0308769 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01559761 0,03084377 ! renal system process GO:0003014 12 12 0,000 0,01559761 0,03081071 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01559761 0,03077772 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01559761 0,0307448 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01559761 0,03071196 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01559761 0,03067918 ! pallium development GO:0021543 13 12 0,000 0,01559761 0,03064647 ! cell fate determination GO:0001709 12 12 0,000 0,01559761 0,03061383 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01559761 0,03058127 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01559761 0,03054877 ! somitogenesis GO:0001756 13 12 0,000 0,01559761 0,03051634 ! G1 phase GO:0051318 13 12 0,000 0,01559761 0,03048398 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01559761 0,03045169 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01559761 0,03041946 ! detection of light stimulus GO:0009583 13 12 0,000 0,01559761 0,03038731 ! synaptogenesis GO:0007416 12 12 0,000 0,01559761 0,03035522 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01559761 0,0303232 ! hormone transport GO:0009914 12 12 0,000 0,01559761 0,03029124 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01559761 0,03025936 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01559761 0,03022754 ! spermatid differentiation GO:0048515 13 12 0,000 0,01559761 0,03019579 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01559761 0,0301641 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01559761 0,03013249 ! neural tube closure GO:0001843 13 12 0,000 0,01559761 0,03010093 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01559761 0,03006945 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01559761 0,03003803 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01559761 0,03000667 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01688759 0,03245447 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01688759 0,03242066 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01688759 0,03238692 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01688759 0,03235326 ! phenol metabolic process GO:0018958 13 13 0,000 0,01688759 0,03231966 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01688759 0,03228614 ! gluconeogenesis GO:0006094 13 13 0,000 0,01688759 0,03225268 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01688759 0,03221929 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01688759 0,03218597 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01688759 0,03215272 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01688759 0,03211954 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01688759 0,03208643 ! regeneration GO:0031099 13 13 0,000 0,01688759 0,03205338 ! keratinization GO:0031424 13 13 0,000 0,01688759 0,03202041 ! post-embryonic development GO:0009791 14 13 0,000 0,01688759 0,0319875 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01688759 0,03195466 ! vasculogenesis GO:0001570 13 13 0,000 0,01688759 0,03192188 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01688759 0,03188917 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01688759 0,03185653 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01688759 0,03182396 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01688759 0,03179146 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01688759 0,03175901 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01688759 0,03172664 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01688759 0,03169433 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01688759 0,03166209 ! autophagy GO:0006914 13 13 0,000 0,01688759 0,03162991 ! receptor metabolic process GO:0043112 14 13 0,000 0,01688759 0,0315978 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01688759 0,03156576 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01688759 0,03153377 ! ureteric bud development GO:0001657 13 13 0,000 0,01688759 0,03150186 ! cell aging GO:0007569 13 13 0,000 0,01688759 0,03147 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01688759 0,03143822 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01688759 0,03140649 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01688759 0,03137483 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01688759 0,03134324 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01688759 0,0313117 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01688759 0,03128024 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01688759 0,03124883 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01688759 0,03121749 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01688759 0,03118621 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01688759 0,03115499 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01688759 0,03112383 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,01688759 0,03109274 ! vasodilation GO:0042311 14 13 0,000 0,01688759 0,03106171 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01688759 0,03103074 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01688759 0,03099984 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01688759 0,03096899 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01688759 0,03093821 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01688759 0,03090748 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01688759 0,03087682 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01688759 0,03084622 ! immunoglobulin production GO:0002377 13 13 0,000 0,01688759 0,03081568 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01688759 0,0307852 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01688759 0,03075478 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01688759 0,03072442 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01688759 0,03069412 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01688759 0,03066388 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01688759 0,0306337 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01688759 0,03060357 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01688759 0,03057351 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01688759 0,03054351 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01688759 0,03051356 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01688759 0,03048368 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01688759 0,03045385 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01688759 0,03042408 ! blastocyst development GO:0001824 13 13 0,000 0,01688759 0,03039437 ! telomere organization GO:0032200 13 13 0,000 0,01688759 0,03036472 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01688759 0,03033512 ! regulation of amine transport GO:0051952 13 13 0,000 0,01688759 0,03030558 ! tissue homeostasis GO:0001894 13 13 0,000 0,01688759 0,0302761 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01688759 0,03024668 ! protein tetramerization GO:0051262 13 13 0,000 0,01688759 0,03021732 ! neuron fate commitment GO:0048663 14 14 0,000 0,01817608 0,03249128 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01817608 0,03245979 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01817608 0,03242837 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01817608 0,03239701 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01817608 0,03236571 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01817608 0,03233447 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01817608 0,03230329 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01817608 0,03227217 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01817608 0,03224111 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01817608 0,0322101 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01817608 0,03217916 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01817608 0,03214828 ! vesicle docking GO:0048278 14 14 0,000 0,01817608 0,03211746 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01817608 0,03208669 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01817608 0,03205599 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01817608 0,03202534 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01817608 0,03199475 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01817608 0,03196423 ! hair cycle GO:0042633 14 14 0,000 0,01817608 0,03193375 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01817608 0,03190334 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01817608 0,03187299 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01817608 0,03184269 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01817608 0,03181245 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01817608 0,03178227 ! lysosome organization GO:0007040 14 14 0,000 0,01817608 0,03175214 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01817608 0,03172207 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01817608 0,03169206 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01817608 0,03166211 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01817608 0,03163221 ! primary neural tube formation GO:0014020 15 14 0,000 0,01817608 0,03160237 ! peptide cross-linking GO:0018149 14 14 0,000 0,01817608 0,03157258 ! regulation of behavior GO:0050795 14 14 0,000 0,01817608 0,03154285 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01817608 0,03151318 ! base-excision repair GO:0006284 14 14 0,000 0,01817608 0,03148356 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01817608 0,031454 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01817608 0,03142449 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01817608 0,03139504 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01817608 0,03136564 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01817608 0,0313363 ! collagen fibril organization GO:0030199 14 14 0,000 0,01817608 0,03130702 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01817608 0,03127779 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01817608 0,03124861 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01817608 0,03121949 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01817608 0,03119042 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01817608 0,0311614 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01817608 0,03113244 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01817608 0,03110354 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01817608 0,03107468 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01817608 0,03104588 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01946306 0,03321335 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01946306 0,03318262 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01946306 0,03315196 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01946306 0,03312134 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01946306 0,03309079 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01946306 0,03306029 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01946306 0,03302985 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01946306 0,03299946 ! response to vitamin GO:0033273 15 15 0,000 0,01946306 0,03296913 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01946306 0,03293886 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01946306 0,03290864 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01946306 0,03287847 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01946306 0,03284837 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01946306 0,03281831 ! ovarian follicle development GO:0001541 15 15 0,000 0,01946306 0,03278831 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01946306 0,03275837 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01946306 0,03272848 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01946306 0,03269865 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01946306 0,03266887 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01946306 0,03263914 ! heme metabolic process GO:0042168 15 15 0,000 0,01946306 0,03260947 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01946306 0,03257985 ! response to starvation GO:0042594 15 15 0,000 0,01946306 0,03255029 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01946306 0,03252078 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01946306 0,03249132 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01946306 0,03246191 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01946306 0,03243256 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01946306 0,03240327 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01946306 0,03237402 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01946306 0,03234483 ! phospholipid transport GO:0015914 15 15 0,000 0,01946306 0,03231569 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01946306 0,0322866 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01946306 0,03225757 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01946306 0,03222859 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01946306 0,03219965 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01946306 0,03217078 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01946306 0,03214195 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01946306 0,03211317 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01946306 0,03208445 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01946306 0,03205578 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01946306 0,03202716 ! protein homooligomerization GO:0051260 15 15 0,000 0,01946306 0,03199859 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01946306 0,03197007 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02074854 0,03405125 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02074854 0,03402096 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02074854 0,03399072 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02074854 0,03396053 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,02074854 0,0339304 ! learning GO:0007612 16 16 0,000 0,02074854 0,03390032 ! circadian rhythm GO:0007623 16 16 0,000 0,02074854 0,03387029 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02074854 0,03384032 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02074854 0,0338104 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02074854 0,03378053 ! vacuole organization GO:0007033 16 16 0,000 0,02074854 0,03375071 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02074854 0,03372095 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02074854 0,03369124 ! vesicle targeting GO:0006903 17 16 0,000 0,02074854 0,03366158 ! segmentation GO:0035282 17 16 0,000 0,02074854 0,03363198 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02074854 0,03360242 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02074854 0,03357292 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02074854 0,03354347 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02074854 0,03351407 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02074854 0,03348473 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02074854 0,03345543 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02074854 0,03342619 ! cell fate specification GO:0001708 16 16 0,000 0,02074854 0,03339699 ! pentose metabolic process GO:0019321 16 16 0,000 0,02074854 0,03336785 ! fatty acid transport GO:0015908 16 16 0,000 0,02074854 0,03333876 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02074854 0,03330972 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02074854 0,03328073 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02074854 0,03325179 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02074854 0,0332229 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02074854 0,03319406 ! polyol metabolic process GO:0019751 16 16 0,000 0,02074854 0,03316527 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02074854 0,03313653 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02074854 0,03310784 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02074854 0,0330792 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02074854 0,03305061 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02074854 0,03302207 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02074854 0,03299358 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02074854 0,03296514 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02074854 0,03293674 ! regulation of coagulation GO:0050818 17 16 0,000 0,02074854 0,0329084 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,02203252 0,03491482 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,02203252 0,03488483 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,02203252 0,03485488 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,02203252 0,03482499 ! myelination GO:0042552 17 17 0,000 0,02203252 0,03479515 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,02203252 0,03476536 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,02203252 0,03473562 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,02203252 0,03470593 ! leukocyte adhesion GO:0007159 17 17 0,000 0,02203252 0,03467629 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,02203252 0,03464671 ! sensory perception of smell GO:0007608 17 17 0,000 0,02203252 0,03461717 ! glucose transport GO:0015758 17 17 0,000 0,02203252 0,03458768 ! cell junction assembly GO:0034329 18 17 0,000 0,02203252 0,03455825 ! tissue remodeling GO:0048771 17 17 0,000 0,02203252 0,03452886 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,02203252 0,03449952 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,02203252 0,03447024 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,02203252 0,034441 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,02203252 0,03441181 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,02203252 0,03438268 ! neural crest cell development GO:0014032 19 17 0,000 0,02203252 0,03435359 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,02203252 0,03432455 ! negative regulation of cell development GO:0010721 18 17 0,000 0,02203252 0,03429556 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,02203252 0,03426662 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,02203252 0,03423772 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,02203252 0,03420888 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,02203252 0,03418008 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,02203252 0,03415134 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,02203252 0,03412264 ! pigmentation GO:0043473 17 17 0,000 0,02203252 0,03409399 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,02203252 0,03406539 ! adult locomotory behavior GO:0008344 17 17 0,000 0,02203252 0,03403683 ! embryonic organ development GO:0048568 17 17 0,000 0,02203252 0,03400832 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,02203252 0,03397987 ! liver development GO:0001889 17 17 0,000 0,02203252 0,03395145 ! gene silencing GO:0016458 17 17 0,000 0,02203252 0,03392309 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,02331501 0,03586775 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,02331501 0,03583783 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,02331501 0,03580797 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,02331501 0,03577815 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,02331501 0,03574839 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,02331501 0,03571867 ! membrane docking GO:0022406 18 18 0,000 0,02331501 0,03568901 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,02331501 0,03565939 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,02331501 0,03562982 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,02331501 0,0356003 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,02331501 0,03557083 ! hexose transport GO:0008645 18 18 0,000 0,02331501 0,03554141 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,02331501 0,03551204 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,02331501 0,03548271 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,02331501 0,03545344 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,02331501 0,03542421 ! ceramide metabolic process GO:0006672 18 18 0,000 0,02331501 0,03539503 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,02331501 0,0353659 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,02331501 0,03533681 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,02331501 0,03530778 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,02331501 0,03527879 ! B cell differentiation GO:0030183 18 18 0,000 0,02331501 0,03524985 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,02331501 0,03522095 ! ensheathment of neurons GO:0007272 18 18 0,000 0,02331501 0,03519211 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,02331501 0,03516331 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,02331501 0,03513456 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,02331501 0,03510585 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,02331501 0,03507719 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,02331501 0,03504858 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,024596 0,03694412 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,024596 0,03691403 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,024596 0,036884 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,024596 0,03685401 ! glial cell differentiation GO:0010001 19 19 0,000 0,024596 0,03682407 ! regulation of pH GO:0006885 19 19 0,000 0,024596 0,03679418 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,024596 0,03676434 ! feeding behavior GO:0007631 19 19 0,000 0,024596 0,03673455 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,024596 0,0367048 ! peroxisome organization GO:0007031 19 19 0,000 0,024596 0,03667511 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,024596 0,03664546 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,024596 0,03661586 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,024596 0,0365863 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,024596 0,0365568 ! metanephros development GO:0001656 19 19 0,000 0,024596 0,03652734 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,024596 0,03649793 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,024596 0,03646857 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,024596 0,03643925 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,024596 0,03640998 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,024596 0,03638076 ! peripheral nervous system development GO:0007422 19 19 0,000 0,024596 0,03635159 ! regulation of protein stability GO:0031647 19 19 0,000 0,024596 0,03632246 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,024596 0,03629338 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,024596 0,03626434 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,024596 0,03623536 ! eye morphogenesis GO:0048592 19 19 0,000 0,024596 0,03620641 ! regulation of cell shape GO:0008360 21 19 0,000 0,024596 0,03617752 ! placenta development GO:0001890 19 19 0,000 0,024596 0,03614867 ! response to heat GO:0009408 19 19 0,000 0,024596 0,03611987 ! vesicle localization GO:0051648 20 19 0,000 0,024596 0,03609111 ! regulation of muscle development GO:0048634 21 20 0,000 0,0258755 0,03793838 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0258755 0,03790822 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0258755 0,03787811 ! negative regulation of binding GO:0051100 21 20 0,000 0,0258755 0,03784805 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0258755 0,03781804 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0258755 0,03778807 ! neural tube development GO:0021915 21 20 0,000 0,0258755 0,03775815 ! phagocytosis GO:0006909 21 20 0,000 0,0258755 0,03772828 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,0258755 0,03769846 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0258755 0,03766868 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0258755 0,03763895 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0258755 0,03760926 ! chromatin remodeling GO:0006338 20 20 0,000 0,0258755 0,03757963 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0258755 0,03755004 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,0258755 0,03752049 ! lipid oxidation GO:0034440 20 20 0,000 0,0258755 0,037491 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0258755 0,03746154 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0258755 0,03743214 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0258755 0,03740278 ! RNA modification GO:0009451 20 20 0,000 0,0258755 0,03737347 ! single fertilization GO:0007338 21 20 0,000 0,0258755 0,0373442 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0258755 0,03731498 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,02715351 0,03912737 ! mRNA catabolic process GO:0006402 21 21 0,000 0,02715351 0,03909681 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,02715351 0,03906628 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,02715351 0,03903581 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,02715351 0,03900539 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,02715351 0,03897501 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,02715351 0,03894468 ! Notch signaling pathway GO:0007219 22 21 0,000 0,02715351 0,03891439 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,02715351 0,03888416 ! ear morphogenesis GO:0042471 21 21 0,000 0,02715351 0,03885397 ! organic anion transport GO:0015711 21 21 0,000 0,02715351 0,03882383 ! cholesterol transport GO:0030301 21 21 0,000 0,02715351 0,03879373 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,02715351 0,03876368 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,02715351 0,03873368 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,02715351 0,03870372 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,02715351 0,03867381 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,02715351 0,03864395 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,02715351 0,03861413 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,02715351 0,03858436 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,02715351 0,03855463 ! regulation of proteolysis GO:0030162 21 21 0,000 0,02715351 0,03852495 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,02715351 0,03849532 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,02715351 0,03846573 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,02715351 0,03843618 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,02843002 0,04021222 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,02843002 0,04018139 ! sister chromatid segregation GO:0000819 22 22 0,000 0,02843002 0,0401506 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,02843002 0,04011985 ! regulation of ion transport GO:0043269 22 22 0,000 0,02843002 0,04008916 ! odontogenesis GO:0042476 22 22 0,000 0,02843002 0,04005851 ! cell junction organization GO:0034330 23 22 0,000 0,02843002 0,04002791 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,02843002 0,03999735 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,02843002 0,03996684 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,02843002 0,03993638 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,02843002 0,03990596 ! ovulation cycle process GO:0022602 22 22 0,000 0,02843002 0,03987559 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,02843002 0,03984527 ! cell chemotaxis GO:0060326 23 22 0,000 0,02843002 0,03981499 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,02843002 0,03978476 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,02843002 0,03975457 ! male sex differentiation GO:0046661 22 22 0,000 0,02843002 0,03972443 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,02843002 0,03969434 ! biopolymer methylation GO:0043414 22 22 0,000 0,02843002 0,03966429 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,02843002 0,03963429 ! detection of external stimulus GO:0009581 23 22 0,000 0,02843002 0,03960433 ! neuron migration GO:0001764 22 22 0,000 0,02843002 0,03957442 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,02843002 0,03954455 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,02843002 0,03951473 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,02843002 0,03948495 ! aerobic respiration GO:0009060 22 22 0,000 0,02843002 0,03945522 ! cytokine production GO:0001816 22 22 0,000 0,02843002 0,03942553 ! cytokinesis GO:0000910 23 22 0,000 0,02843002 0,03939589 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,02843002 0,03936629 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,02970505 0,0411009 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,02970505 0,04107007 ! viral infectious cycle GO:0019058 23 23 0,000 0,02970505 0,04103928 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,02970505 0,04100854 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,02970505 0,04097785 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,02970505 0,0409472 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,02970505 0,04091659 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,02970505 0,04088604 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,02970505 0,04085552 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,02970505 0,04082506 ! endocrine system development GO:0035270 23 23 0,000 0,02970505 0,04079464 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,02970505 0,04076426 ! female gonad development GO:0008585 23 23 0,000 0,02970505 0,04073393 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,02970505 0,04070364 ! lipid homeostasis GO:0055088 23 23 0,000 0,02970505 0,0406734 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,02970505 0,04064321 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,02970505 0,04061306 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,02970505 0,04058295 ! cell projection assembly GO:0030031 25 23 0,000 0,02970505 0,04055289 ! mitochondrial transport GO:0006839 24 24 0,000 0,03097859 0,0422602 ! regulation of action potential GO:0001508 24 24 0,000 0,03097859 0,04222894 ! gliogenesis GO:0042063 24 24 0,000 0,03097859 0,04219773 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,03097859 0,04216657 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,03097859 0,04213545 ! glucose homeostasis GO:0042593 24 24 0,000 0,03097859 0,04210438 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,03097859 0,04207335 ! T cell differentiation GO:0030217 24 24 0,000 0,03097859 0,04204237 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,03097859 0,04201143 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,03097859 0,04198054 ! ovulation cycle GO:0042698 24 24 0,000 0,03097859 0,04194969 ! fertilization GO:0009566 25 24 0,000 0,03097859 0,04191889 ! maintenance of protein location GO:0045185 25 24 0,000 0,03097859 0,04188814 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,03097859 0,04185743 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,03097859 0,04182676 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,03097859 0,04179614 ! glucan metabolic process GO:0044042 25 24 0,000 0,03097859 0,04176557 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,03225064 0,04344878 ! negative regulation of secretion GO:0051048 26 25 0,000 0,03225064 0,04341704 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,03225064 0,04338535 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,03225064 0,0433537 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,03225064 0,0433221 ! cellular component disassembly GO:0022411 26 25 0,000 0,03225064 0,04329055 ! endosome transport GO:0016197 25 25 0,000 0,03225064 0,04325904 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,03225064 0,04322758 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,03225064 0,04319617 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,03225064 0,0431648 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,03225064 0,04313347 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,03225064 0,04310219 ! excretion GO:0007588 25 25 0,000 0,03225064 0,04307096 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,03225064 0,04303977 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,03225064 0,04300863 ! gastrulation GO:0007369 25 25 0,000 0,03225064 0,04297753 ! heart morphogenesis GO:0003007 25 25 0,000 0,03225064 0,04294648 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,03225064 0,04291547 ! regulation of endocytosis GO:0030100 25 25 0,000 0,03225064 0,04288451 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,03225064 0,04285359 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,03225064 0,04282271 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,03225064 0,04279188 ! positive regulation of binding GO:0051099 27 26 0,000 0,03352121 0,04444574 ! positive regulation of defense response GO:0031349 26 26 0,000 0,03352121 0,04441379 ! glycolysis GO:0006096 26 26 0,000 0,03352121 0,04438188 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,03352121 0,04435002 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,03352121 0,04431821 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,03352121 0,04428644 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,03352121 0,04425472 ! cellular defense response GO:0006968 26 26 0,000 0,03352121 0,04422304 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,03352121 0,0441914 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,03352121 0,04415982 ! double-strand break repair GO:0006302 27 26 0,000 0,03352121 0,04412827 ! regulation of protein secretion GO:0050708 26 26 0,000 0,03352121 0,04409678 ! germ cell development GO:0007281 27 26 0,000 0,03352121 0,04406532 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,03352121 0,04403392 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,03352121 0,04400255 ! maintenance of location in cell GO:0051651 27 26 0,000 0,03352121 0,04397123 ! synapse organization GO:0050808 26 26 0,000 0,03352121 0,04393996 ! chloride transport GO:0006821 27 27 0,000 0,03479029 0,04557108 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,03479029 0,04553871 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,03479029 0,04550639 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,03479029 0,04547412 ! learning or memory GO:0007611 28 27 0,000 0,03479029 0,04544189 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,03479029 0,04540971 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,03479029 0,04537757 ! peptide metabolic process GO:0006518 29 27 0,000 0,03479029 0,04534548 ! activation of caspase activity GO:0006919 27 27 0,000 0,03479029 0,04531343 ! mesenchymal cell development GO:0014031 29 27 0,000 0,03479029 0,04528143 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,03479029 0,04524948 ! defense response to bacterium GO:0042742 27 27 0,000 0,03479029 0,04521757 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,03479029 0,0451857 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,03479029 0,04515388 ! cell growth GO:0016049 27 27 0,000 0,03479029 0,0451221 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,0360579 0,04673326 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0360579 0,04670042 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0360579 0,04666763 ! carbohydrate transport GO:0008643 28 28 0,000 0,0360579 0,04663488 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0360579 0,04660217 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0360579 0,04656952 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0360579 0,04653691 ! histone modification GO:0016570 28 28 0,000 0,0360579 0,04650434 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,0360579 0,04647182 ! developmental growth GO:0048589 28 28 0,000 0,0360579 0,04643934 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,0360579 0,04640691 ! cartilage development GO:0051216 29 28 0,000 0,0360579 0,04637453 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,03732402 0,04796943 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,03732402 0,047936 ! viral reproductive process GO:0022415 29 29 0,000 0,03732402 0,04790262 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,03732402 0,04786929 ! leukocyte migration GO:0050900 30 29 0,000 0,03732402 0,047836 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,03732402 0,04780276 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,03732402 0,04776956 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,03732402 0,04773641 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,03732402 0,04770331 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,03732402 0,04767025 ! tRNA processing GO:0008033 29 29 0,000 0,03732402 0,04763723 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,03732402 0,04760427 ! covalent chromatin modification GO:0016569 29 29 0,000 0,03732402 0,04757135 ! adult behavior GO:0030534 30 29 0,000 0,03732402 0,04753847 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,03732402 0,04750564 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,03732402 0,04747285 ! response to UV GO:0009411 29 29 0,000 0,03732402 0,04744011 ! transition metal ion transport GO:0000041 31 30 0,000 0,03858866 0,04901372 ! RNA catabolic process GO:0006401 30 30 0,000 0,03858866 0,04897996 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,03858866 0,04894625 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,03858866 0,04891259 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,03858866 0,04887897 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,03858866 0,0488454 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,03858866 0,04881188 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,03858866 0,0487784 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,03858866 0,04874497 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,03858866 0,04871158 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,03858866 0,04867824 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,03858866 0,04864494 ! response to temperature stimulus GO:0009266 30 30 0,000 0,03858866 0,04861169 ! regulation of ossification GO:0030278 30 30 0,000 0,03858866 0,04857849 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,03858866 0,04854533 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,03858866 0,04851222 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,03858866 0,04847915 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,03858866 0,04844612 ! vesicle organization GO:0016050 30 30 0,000 0,03858866 0,04841314 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,03858866 0,04838021 ! establishment of organelle localization GO:0051656 31 30 0,000 0,03858866 0,04834732 ! regulation of translational initiation GO:0006446 31 31 0,000 0,03985183 0,04989601 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,03985183 0,04986214 ! membrane fusion GO:0006944 31 31 0,000 0,03985183 0,04982831 ! B cell activation GO:0042113 31 31 0,000 0,03985183 0,04979453 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,03985183 0,04976079 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,03985183 0,0497271 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,03985183 0,04969345 ! ion transmembrane transport GO:0034220 31 31 0,000 0,03985183 0,04965986 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,03985183 0,0496263 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,03985183 0,04959279 ! digestion GO:0007586 31 31 0,000 0,03985183 0,04955933 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,03985183 0,04952591 ! regulation of DNA replication GO:0006275 32 31 0,000 0,03985183 0,04949254 ! regulation of heart contraction GO:0008016 31 31 0,000 0,03985183 0,04945921 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,03985183 0,04942593 ! camera-type eye development GO:0043010 31 31 0,000 0,03985183 0,04939269 ! extracellular matrix organization GO:0030198 31 31 0,000 0,03985183 0,04935949 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,03985183 0,04932634 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,03985183 0,04929324 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,03985183 0,04926018 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,03985183 0,04922716 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,04111352 0,05075166 ! cell redox homeostasis GO:0045454 32 32 0,000 0,04111352 0,05071769 ! muscle fiber development GO:0048747 32 32 0,000 0,04111352 0,05068376 ! glucose catabolic process GO:0006007 32 32 0,000 0,04111352 0,05064988 ! lipid modification GO:0030258 32 32 0,000 0,04111352 0,05061605 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,04111352 0,05058226 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,04111352 0,05054852 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,04111352 0,05051482 ! cell maturation GO:0048469 32 32 0,000 0,04111352 0,05048116 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,04111352 0,05044755 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,04111352 0,05041399 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,04111352 0,05038047 ! kidney development GO:0001822 32 32 0,000 0,04111352 0,05034699 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,04111352 0,05031356 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,04111352 0,05028018 ! maintenance of location GO:0051235 33 32 0,000 0,04111352 0,05024683 ! negative regulation of cell size GO:0045792 33 33 0,000 0,04237374 0,05175269 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,04237374 0,05171842 ! amino acid transport GO:0006865 33 33 0,000 0,04237374 0,05168419 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,04237374 0,05165001 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,04237374 0,05161587 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,04237374 0,05158178 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,04237374 0,05154773 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,04237374 0,05151373 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,04237374 0,05147977 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,04237374 0,05144586 ! regulation of actin filament length GO:0030832 34 34 0,000 0,04363249 0,05293922 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,04363249 0,05290439 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,04363249 0,05286961 ! response to metal ion GO:0010038 34 34 0,000 0,04363249 0,05283487 ! ear development GO:0043583 34 34 0,000 0,04363249 0,05280018 ! muscle cell differentiation GO:0042692 35 34 0,000 0,04363249 0,05276554 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,04363249 0,05273094 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,04363249 0,05269638 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,04363249 0,05266187 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,04363249 0,05262741 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,04363249 0,05259299 ! secondary metabolic process GO:0019748 34 34 0,000 0,04363249 0,05255861 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,04363249 0,05252428 ! viral reproduction GO:0016032 34 34 0,000 0,04363249 0,05249 ! detection of stimulus GO:0051606 36 34 0,000 0,04363249 0,05245576 ! acute inflammatory response GO:0002526 35 35 0,000 0,04488977 0,0539321 ! regulation of cellular component size GO:0032535 35 35 0,000 0,04488977 0,05389696 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,04488977 0,05386187 ! mesoderm development GO:0007498 35 35 0,000 0,04488977 0,05382683 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,04488977 0,05379183 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,04488977 0,05375688 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,04488977 0,05372197 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,04488977 0,05368711 ! inorganic anion transport GO:0015698 35 35 0,000 0,04488977 0,05365229 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,04488977 0,05361752 ! regulation of immune effector process GO:0002697 35 35 0,000 0,04488977 0,0535828 ! hydrogen transport GO:0006818 36 36 0,000 0,04614557 0,05504614 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,04614557 0,05501054 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,04614557 0,05497498 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,04614557 0,05493946 ! regulation of mitosis GO:0007088 37 36 0,000 0,04614557 0,05490399 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,04614557 0,05486857 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,04614557 0,0548332 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,04614557 0,05479787 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,04614557 0,05476258 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,04614557 0,05472734 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,04614557 0,05469215 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,04614557 0,054657 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,04614557 0,05462189 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,04614557 0,05458683 ! gonad development GO:0008406 36 36 0,000 0,04614557 0,05455182 ! regulation of lipase activity GO:0060191 36 36 0,000 0,04614557 0,05451685 ! activation of immune response GO:0002253 36 36 0,000 0,04614557 0,05448193 ! coagulation GO:0050817 39 36 0,000 0,04614557 0,05444705 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,04739991 0,05589126 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,04739991 0,05585552 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 0,000 0,04739991 0,05581983 ! lung development GO:0030324 38 37 0,000 0,04739991 0,05578418 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,04739991 0,05574859 ! eye development GO:0001654 37 37 0,000 0,04739991 0,05571303 ! negative regulation of growth GO:0045926 37 37 0,000 0,04739991 0,05567752 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,04739991 0,05564206 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,04739991 0,05560664 ! adaptive immune response GO:0002250 37 37 0,000 0,04739991 0,05557127 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,04865278 0,05700386 ! neurotransmitter transport GO:0006836 40 38 0,000 0,04865278 0,05696765 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,04865278 0,05693148 ! exocytosis GO:0006887 40 38 0,000 0,04865278 0,05689535 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,04865278 0,05685927 ! urogenital system development GO:0001655 38 38 0,000 0,04865278 0,05682324 ! hexose catabolic process GO:0019320 38 38 0,000 0,04865278 0,05678725 ! RNA elongation GO:0006354 38 38 0,000 0,04865278 0,05675131 ! axon guidance GO:0007411 39 38 0,000 0,04865278 0,05671542 ! regulation of neurological system process GO:0031644 38 38 0,000 0,04865278 0,05667957 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,04865278 0,05664376 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,04865278 0,056608 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,04990419 0,05802739 ! hemostasis GO:0007599 42 39 0,000 0,04990419 0,05799081 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,04990419 0,05795426 ! activation of MAPK activity GO:0000187 39 39 0,000 0,04990419 0,05791777 ! respiratory tube development GO:0030323 40 39 0,000 0,04990419 0,05788132 ! response to unfolded protein GO:0006986 39 39 0,000 0,04990419 0,05784492 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,04990419 0,05780856 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,04990419 0,05777225 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,04990419 0,05773598 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,04990419 0,05769976 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,04990419 0,05766359 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,04990419 0,05762745 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,04990419 0,05759137 ! respiratory system development GO:0060541 40 39 0,000 0,04990419 0,05755533 ! developmental maturation GO:0021700 39 39 0,000 0,04990419 0,05751934 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,04990419 0,05748339 ! limb development GO:0060173 39 39 0,000 0,04990419 0,05744748 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,04990419 0,05741162 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,04990419 0,05737581 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,05115413 0,05877622 ! DNA catabolic process GO:0006308 41 40 0,000 0,05115413 0,0587396 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,05115413 0,05870303 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,05115413 0,0586665 ! organelle localization GO:0051640 41 40 0,000 0,05115413 0,05863001 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,05240261 0,06002363 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,05240261 0,05998634 ! amine catabolic process GO:0009310 42 41 0,000 0,05240261 0,05994911 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,05240261 0,05991192 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,05240261 0,05987478 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,05240261 0,05983768 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,05240261 0,05980063 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,05364963 0,06118581 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,05364963 0,06114797 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,05364963 0,06111018 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,05364963 0,06107244 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,05364963 0,06103474 ! protein ubiquitination GO:0016567 43 42 0,000 0,05364963 0,06099708 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,05364963 0,06095948 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,05364963 0,06092192 ! forebrain development GO:0030900 43 42 0,000 0,05364963 0,06088441 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,05364963 0,06084694 ! reproductive structure development GO:0048608 43 43 0,000 0,0548952 0,06222131 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,0548952 0,06218306 ! alcohol catabolic process GO:0046164 43 43 0,000 0,0548952 0,06214487 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,0548952 0,06210672 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,0548952 0,06206862 ! humoral immune response GO:0006959 44 44 0,000 0,0561393 0,06343638 ! mRNA transport GO:0051028 44 44 0,000 0,0561393 0,06339751 ! protein import into nucleus GO:0006606 44 44 0,000 0,0561393 0,06335868 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,0561393 0,06331991 ! vitamin metabolic process GO:0006766 44 44 0,000 0,0561393 0,06328118 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,0561393 0,0632425 ! amine biosynthetic process GO:0009309 46 45 0,000 0,05738195 0,06460289 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,05738195 0,06456345 ! regulation of DNA binding GO:0051101 47 45 0,000 0,05738195 0,06452406 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,05738195 0,06448471 ! nuclear import GO:0051170 45 45 0,000 0,05738195 0,06444542 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,05738195 0,06440617 ! protein processing GO:0016485 45 45 0,000 0,05738195 0,06436697 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,05862314 0,06571925 ! tube morphogenesis GO:0035239 47 46 0,000 0,05862314 0,0656793 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,05862314 0,0656394 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,05862314 0,06559955 ! regulation of membrane potential GO:0042391 46 46 0,000 0,05862314 0,06555974 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,05986288 0,06690558 ! regulation of blood pressure GO:0008217 48 47 0,000 0,05986288 0,06686503 ! sex differentiation GO:0007548 47 47 0,000 0,05986288 0,06682453 ! amine transport GO:0015837 47 47 0,000 0,05986288 0,06678408 ! rhythmic process GO:0048511 47 47 0,000 0,05986288 0,06674368 ! regulation of catabolic process GO:0009894 48 47 0,000 0,05986288 0,06670332 ! calcium ion transport GO:0006816 48 48 0,000 0,06110117 0,06804197 ! actin filament organization GO:0007015 50 48 0,000 0,06110117 0,06800088 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,06110117 0,06795985 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,06110117 0,06791886 ! protein localization in nucleus GO:0034504 48 48 0,000 0,06110117 0,06787792 ! DNA recombination GO:0006310 48 48 0,000 0,06110117 0,06783703 ! leukocyte differentiation GO:0002521 50 49 0,000 0,06233801 0,06916855 ! ossification GO:0001503 50 49 0,000 0,06233801 0,06912693 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,06233801 0,06908536 ! cell cycle arrest GO:0007050 49 49 0,000 0,06233801 0,06904385 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,06233801 0,06900238 ! divalent metal ion transport GO:0070838 49 49 0,000 0,06233801 0,06896096 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,06233801 0,06891959 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,06233801 0,06887827 ! response to bacterium GO:0009617 50 49 0,000 0,06233801 0,068837 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,06233801 0,06879578 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,06233801 0,06875461 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,06233801 0,06871349 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,06357341 0,07003334 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,06357341 0,06999151 ! negative regulation of transport GO:0051051 51 50 0,000 0,06357341 0,06994972 ! chromatin assembly GO:0031497 50 50 0,000 0,06357341 0,06990799 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,06357341 0,0698663 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,06357341 0,06982466 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,06357341 0,06978308 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,06357341 0,06974154 ! transcription initiation GO:0006352 50 50 0,000 0,06357341 0,06970005 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,06357341 0,06965861 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,06357341 0,06961722 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,06480735 0,07092633 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,06480735 0,07088424 ! positive regulation of immune response GO:0050778 51 51 0,000 0,06480735 0,0708422 ! rRNA metabolic process GO:0016072 51 51 0,000 0,06480735 0,0708002 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,06480735 0,07075826 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,06480735 0,07071637 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,06480735 0,07067452 ! protein maturation GO:0051604 51 51 0,000 0,06480735 0,07063273 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,06603985 0,07193348 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,06603985 0,07189099 ! cell fate commitment GO:0045165 52 52 0,000 0,06603985 0,07184855 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,06603985 0,07180616 ! response to light stimulus GO:0009416 53 52 0,000 0,06603985 0,07176382 ! sodium ion transport GO:0006814 53 53 0,000 0,0672709 0,0730585 ! tRNA metabolic process GO:0006399 53 53 0,000 0,0672709 0,07301547 ! response to hypoxia GO:0001666 53 53 0,000 0,0672709 0,0729725 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,0672709 0,07292957 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,0672709 0,0728867 ! regulation of T cell activation GO:0050863 53 53 0,000 0,0672709 0,07284387 ! regulation of protein transport GO:0051223 53 53 0,000 0,0672709 0,0728011 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,06850051 0,07408829 ! response to oxygen levels GO:0070482 55 54 0,000 0,06850051 0,07404484 ! response to virus GO:0009615 54 54 0,000 0,06850051 0,07400144 ! hormone metabolic process GO:0042445 55 54 0,000 0,06850051 0,07395808 ! sulfur metabolic process GO:0006790 55 54 0,000 0,06850051 0,07391478 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,06850051 0,07387153 ! nucleosome organization GO:0034728 55 55 0,000 0,06972869 0,07515203 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,06972869 0,07510811 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,06972869 0,07506423 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,06972869 0,07502041 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,07095542 0,0762957 ! reproductive developmental process GO:0003006 56 56 0,000 0,07095542 0,07625122 ! extracellular structure organization GO:0043062 56 56 0,000 0,07095542 0,07620678 ! regulation of nervous system development GO:0051960 57 56 0,000 0,07095542 0,0761624 ! regulation of binding GO:0051098 60 57 0,000 0,07218071 0,07743251 ! ATP metabolic process GO:0046034 57 57 0,000 0,07218071 0,07738746 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,07218071 0,07734247 ! regulation of protein localization GO:0032880 58 57 0,000 0,07218071 0,07729753 ! innate immune response GO:0045087 58 58 0,000 0,07340457 0,0785625 ! dephosphorylation GO:0016311 60 59 0,000 0,07462699 0,07982446 ! carboxylic acid transport GO:0046942 59 59 0,000 0,07462699 0,07977816 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,07462699 0,07973191 ! regulation of cell development GO:0060284 60 59 0,000 0,07462699 0,07968571 ! sterol metabolic process GO:0016125 59 59 0,000 0,07462699 0,07963957 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,07462699 0,07959348 ! protein localization in organelle GO:0033365 59 59 0,000 0,07462699 0,07954745 ! immune effector process GO:0002252 59 59 0,000 0,07462699 0,07950147 ! potassium ion transport GO:0006813 60 60 0,000 0,07584798 0,08075553 ! protein polymerization GO:0051258 65 60 0,000 0,07584798 0,0807089 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,07706753 0,0819593 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,07706753 0,08191203 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,07706753 0,08186482 ! lipid transport GO:0006869 62 62 0,000 0,07828566 0,08311087 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,07828566 0,08306302 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,07828566 0,08301523 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,07828566 0,08296749 ! protein import GO:0017038 62 62 0,000 0,07828566 0,08291981 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,07828566 0,08287218 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,07828566 0,08282461 ! regulation of secretion GO:0051046 65 63 0,000 0,07950235 0,08406359 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,07950235 0,08401539 ! glucose metabolic process GO:0006006 63 63 0,000 0,07950235 0,08396724 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,07950235 0,08391915 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,07950235 0,08387111 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,08071762 0,08510445 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,08071762 0,08505579 ! angiogenesis GO:0001525 65 64 0,000 0,08071762 0,08500718 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,08071762 0,08495864 ! anion transport GO:0006820 65 65 0,000 0,08193146 0,08618703 ! regulation of hormone levels GO:0010817 66 65 0,000 0,08193146 0,08613787 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,08314388 0,08736269 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,08314388 0,08731291 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,08314388 0,08726319 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,08314388 0,08721353 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,08435487 0,08843346 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,08435487 0,08838319 ! muscle contraction GO:0006936 67 67 0,000 0,08435487 0,08833297 ! striated muscle tissue development GO:0014706 69 67 0,000 0,08435487 0,08828281 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,08435487 0,0882327 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,08435487 0,08818266 ! response to radiation GO:0009314 70 68 0,000 0,08556444 0,08939641 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,08556444 0,08934576 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,08556444 0,08929517 ! sensory perception of sound GO:0007605 71 69 0,000 0,08677259 0,09050475 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,08677259 0,09045355 ! response to nutrient levels GO:0031667 69 69 0,000 0,08677259 0,09040242 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,08677259 0,09035135 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,08677259 0,09030033 ! positive regulation of transport GO:0051050 71 70 0,000 0,08797932 0,09150445 ! cell part morphogenesis GO:0032990 75 70 0,000 0,08797932 0,09145284 ! wound healing GO:0042060 74 70 0,000 0,08797932 0,09140129 ! growth GO:0040007 70 70 0,000 0,08797932 0,0913498 ! muscle tissue development GO:0060537 72 70 0,000 0,08797932 0,09129836 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,08797932 0,09124698 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,08918464 0,09244504 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,08918464 0,09239308 ! regulation of cell migration GO:0030334 71 71 0,000 0,08918464 0,09234117 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,08918464 0,09228932 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,08918464 0,09223753 ! secretion by cell GO:0032940 75 72 0,000 0,09038853 0,09343021 ! muscle system process GO:0003012 72 72 0,000 0,09038853 0,09337784 ! sensory organ development GO:0007423 72 72 0,000 0,09038853 0,09332553 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,09038853 0,09327327 ! regulation of cytokine production GO:0001817 72 72 0,000 0,09038853 0,09322108 ! electron transport chain GO:0022900 75 74 0,000 0,09279209 0,09564643 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,09279209 0,09559296 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,09399174 0,09677474 ! response to oxidative stress GO:0006979 76 75 0,000 0,09399174 0,09672071 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,09399174 0,09666673 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,09518999 0,09784448 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,09638683 0,09901947 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,09638683 0,0989643 ! microtubule-based movement GO:0007018 82 78 0,000 0,09758226 0,10013592 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,09758226 0,10008019 ! metal ion homeostasis GO:0055065 78 78 0,000 0,09758226 0,10002453 ! regulation of immune response GO:0050776 78 78 0,000 0,09758226 0,09996893 ! regulation of locomotion GO:0040012 79 79 0,000 0,09877629 0,10113594 ! regulation of cell motion GO:0051270 79 79 0,000 0,09877629 0,10107979 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,09996891 0,10224345 ! neuron projection development GO:0031175 85 80 0,000 0,09996891 0,10218674 ! MAPKKK cascade GO:0000165 82 81 0,000 0,10116012 0,10334707 ! tube development GO:0035295 83 81 0,000 0,10116012 0,10328981 ! lymphocyte activation GO:0046649 82 81 0,000 0,10116012 0,10323262 ! lipid catabolic process GO:0016042 82 81 0,000 0,10116012 0,10317549 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,10353836 0,10554269 ! ncRNA processing GO:0034470 83 83 0,000 0,10353836 0,10548435 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,10353836 0,10542607 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,10472537 0,10657585 ! regulation of cellular localization GO:0060341 86 85 0,000 0,10591099 0,10772294 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,10591099 0,10766352 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,10591099 0,10760417 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,10591099 0,10754488 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,10709522 0,10868749 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,10709522 0,10862767 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,10709522 0,10856792 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,10709522 0,10850824 ! male gamete generation GO:0048232 90 88 0,000 0,10945948 0,11084276 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,10945948 0,11078189 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,10945948 0,11072109 ! chemotaxis GO:0006935 90 89 0,000 0,11063953 0,11185335 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,11063953 0,11179202 ! brain development GO:0007420 91 90 0,000 0,11181818 0,11292105 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,11299545 0,11404743 ! visual perception GO:0007601 93 92 0,000 0,11417133 0,11517119 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,11417133 0,11510818 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,11417133 0,11504525 ! tissue morphogenesis GO:0048729 94 93 0,000 0,11534582 0,11616522 ! regulation of response to stress GO:0080134 97 94 0,000 0,11651893 0,11728257 ! blood vessel development GO:0001568 95 94 0,000 0,11651893 0,11721855 ! pattern specification process GO:0007389 96 94 0,000 0,11651893 0,1171546 ! cofactor metabolic process GO:0051186 95 94 0,000 0,11651893 0,11709072 ! vasculature development GO:0001944 97 96 0,000 0,118861 0,11937919 ! endocytosis GO:0006897 99 98 0,000 0,12119755 0,12165963 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,12119755 0,1215934 ! blood circulation GO:0008015 99 98 0,000 0,12119755 0,12152725 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,12119755 0,12146116 ! muscle organ development GO:0007517 102 100 0,000 0,12352859 0,12372999 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,12352859 0,12366278 ! response to other organism GO:0051707 101 100 0,000 0,12352859 0,12359565 ! hemopoiesis GO:0030097 104 100 0,000 0,12352859 0,12352859