pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/10456-0-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,929E-09 4,64E-06 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,633E-06 1,964E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,795E-06 1,439E-03 ! interphase GO:0051325 213 98 3,000 2,032E-06 1,223E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 8,321E-06 4,004E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 8,321E-06 3,337E-03 GO:0032862|activation of Rho GTPase activity, ! female meiosis GO:0007143 7 5 1,000 8,321E-06 2,86E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 8,321E-06 2,502E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 8,321E-06 2,224E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 9,948E-06 2,393E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,064E-05 2,326E-03 ! response to UV GO:0009411 104 53 2,000 1,634E-05 3,276E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,326E-05 4,305E-03 ! DNA topological change GO:0006265 12 8 1,000 2,326E-05 3,997E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 2,326E-05 3,731E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,989E-05 4,494E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,989E-05 4,23E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 3,313E-05 4,428E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 3,463E-05 4,386E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 3,463E-05 4,167E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 3,619E-05 4,146E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,734E-05 4,083E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 3,734E-05 3,906E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,734E-05 3,743E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 3,734E-05 3,593E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 3,734E-05 3,455E-03 ! DNA ligation GO:0006266 19 10 1,000 3,734E-05 3,327E-03 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 3,734E-05 3,208E-03 ! oocyte development GO:0048599 17 10 1,000 3,734E-05 3,098E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 4,111E-05 3,297E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 4,111E-05 3,191E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 4,111E-05 3,091E-03 ! meiosis GO:0007126 121 74 2,000 4,463E-05 3,254E-03 GO:0051327|M phase of meiotic cell cycle, ! oocyte differentiation GO:0009994 18 11 1,000 4,561E-05 3,227E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 4,561E-05 3,135E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 4,646E-05 3,105E-03 ! meiotic cell cycle GO:0051321 122 75 2,000 4,646E-05 3,021E-03 ! positive regulation of ligase activity GO:0051351 124 77 2,000 5,027E-05 3,183E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 5,428E-05 3,348E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,47E-05 3,29E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 5,47E-05 3,21E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 6,46E-05 3,701E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 6,52E-05 3,648E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 7,533E-05 4,119E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 7,533E-05 4,028E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 7,533E-05 3,94E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 8,687E-05 4,447E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 8,83E-05 4,426E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of protein ubiquitination GO:0031396 25 16 1,000 9,922E-05 4,872E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 9,922E-05 4,774E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,124E-04 5,302E-03 ! regulation of viral genome replication GO:0045069 28 17 1,000 1,124E-04 5,2E-03 ! skin development GO:0043588 36 19 1,000 1,411E-04 6,407E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,411E-04 6,289E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,567E-04 6,856E-03 ! negative regulation of translation GO:0017148 29 20 1,000 1,567E-04 6,734E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,731E-04 7,308E-03 ! oogenesis GO:0048477 36 21 1,000 1,731E-04 7,182E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 1,731E-04 7,06E-03 ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,903E-04 7,633E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,903E-04 7,507E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,083E-04 8,085E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,083E-04 7,957E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of viral reproduction GO:0050792 38 23 1,000 2,083E-04 7,833E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,272E-04 8,408E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,272E-04 8,281E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,468E-04 8,861E-03 ! chromosome condensation GO:0030261 45 25 1,000 2,468E-04 8,731E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,468E-04 8,605E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,672E-04 9,183E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,884E-04 9,773E-03 ! fat cell differentiation GO:0045444 50 27 1,000 2,884E-04 9,637E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 3,104E-04 0,01023011 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,104E-04 0,01009186 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,332E-04 0,01068873 ! regulation of B cell activation GO:0050864 50 30 1,000 3,568E-04 0,01129503 ! spindle organization GO:0007051 46 32 1,000 4,063E-04 0,01269706 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,866E-04 0,01501017 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 5,149E-04 0,01568293 ! RNA export from nucleus GO:0006405 56 37 1,000 5,441E-04 0,01636245 ! meiosis I GO:0007127 65 37 1,000 5,441E-04 0,01616044 ! nucleus organization GO:0006997 67 38 1,000 5,74E-04 0,01684054 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,74E-04 0,01663764 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 6,683E-04 0,01914257 ! female gamete generation GO:0007292 61 41 1,000 6,683E-04 0,01891736 ! epidermal cell differentiation GO:0009913 68 46 1,000 8,411E-04 0,02353205 ! response to insulin stimulus GO:0032868 95 46 1,000 8,411E-04 0,02326157 ! response to calcium ion GO:0051592 81 47 1,000 8,78E-04 0,02400553 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,157E-04 0,02475358 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,157E-04 0,02447854 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,033E-03 0,02731739 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 1,074E-03 0,02808514 ! cell maturation GO:0048469 100 53 1,000 1,115E-03 0,02885611 ! nuclear export GO:0051168 97 55 1,000 1,201E-03 0,03073061 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 1,427E-03 0,03613894 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,474E-03 0,03695356 ! germ cell development GO:0007281 118 65 1,000 1,672E-03 0,0414735 ! developmental maturation GO:0021700 116 66 1,000 1,723E-03 0,04230883 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,775E-03 0,04314536 ! chromosome segregation GO:0007059 113 67 1,000 1,775E-03 0,0427139 ! negative regulation of cell size GO:0045792 134 69 1,000 1,882E-03 0,04482173 ! regulation of caspase activity GO:0043281 122 72 1,000 2,046E-03 0,04827197 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 2,046E-03 0,04780331 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 2,16E-03 0,04997205 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 2,16E-03 0,04949613 ! regulation of actin filament-based process GO:0032970 152 77 1,000 2,336E-03 0,05302209 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,336E-03 0,05252656 ! regulation of peptidase activity GO:0052547 134 79 1,000 2,457E-03 0,05473411 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,457E-03 0,05423196 ! response to metal ion GO:0010038 140 80 1,000 2,518E-03 0,05508526 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,581E-03 0,0559389 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 2,772E-03 0,05954619 ! response to unfolded protein GO:0006986 131 85 1,000 2,837E-03 0,06040673 ! positive regulation of cell activation GO:0050867 145 85 1,000 2,837E-03 0,05987685 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 2,903E-03 0,06073459 ! mitochondrion organization GO:0007005 148 86 1,000 2,903E-03 0,06021101 ! cellular respiration GO:0045333 135 88 1,000 3,037E-03 0,0624503 ! positive regulation of protein modification process GO:0031401 136 88 1,000 3,037E-03 0,06192106 ! regulation of cell adhesion GO:0030155 212 89 1,000 3,105E-03 0,06277622 ! response to protein stimulus GO:0051789 149 91 1,000 3,243E-03 0,06502407 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 3,528E-03 0,07015227 ! cell cycle arrest GO:0007050 213 100 1,000 3,9E-03 0,07691419 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,64E-03 0,09076702 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,64E-03 0,09003503 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,64E-03 0,08931475 ! neuron fate determination GO:0048664 7 5 0,000 4,64E-03 0,0886059 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,64E-03 0,08790822 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,64E-03 0,08722144 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,64E-03 0,0865453 ! polyol transport GO:0015791 12 5 0,000 4,64E-03 0,08587957 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,64E-03 0,085224 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,64E-03 0,08457836 ! response to superoxide GO:0000303 10 5 0,000 4,64E-03 0,08394244 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,64E-03 0,083316 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,64E-03 0,08269884 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,64E-03 0,08209076 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,64E-03 0,08149156 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,64E-03 0,08090104 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,64E-03 0,08031902 ! cobalt ion transport GO:0006824 11 5 0,000 4,64E-03 0,07974531 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,64E-03 0,07917974 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,64E-03 0,07862214 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,64E-03 0,07807233 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,64E-03 0,07753017 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,64E-03 0,07699548 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,64E-03 0,07646811 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,64E-03 0,07594792 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,64E-03 0,07543476 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,64E-03 0,07492848 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,64E-03 0,07442896 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,64E-03 0,07393605 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,64E-03 0,07344963 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,64E-03 0,07296957 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,64E-03 0,07249574 ! negative chemotaxis GO:0050919 14 5 0,000 4,64E-03 0,07202803 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,64E-03 0,07156631 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,64E-03 0,07111047 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,64E-03 0,0706604 ! behavioral response to pain GO:0048266 9 5 0,000 4,64E-03 0,070216 ! clathrin coat assembly GO:0048268 14 5 0,000 4,64E-03 0,06977715 ! Notch receptor processing GO:0007220 8 5 0,000 4,64E-03 0,06934375 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,64E-03 0,0689157 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,64E-03 0,06849291 ! micturition GO:0060073 9 5 0,000 4,64E-03 0,06807527 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,64E-03 0,06766269 ! copulation GO:0007620 9 5 0,000 4,64E-03 0,06725508 ! glial cell fate commitment GO:0021781 13 5 0,000 4,64E-03 0,06685236 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,64E-03 0,06645443 ! spermidine metabolic process GO:0008216 7 5 0,000 4,64E-03 0,06606121 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,64E-03 0,06567261 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,64E-03 0,06528856 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,64E-03 0,06490898 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,64E-03 0,06453378 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,64E-03 0,0641629 ! grooming behavior GO:0007625 6 5 0,000 4,64E-03 0,06379625 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,64E-03 0,06343377 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,64E-03 0,06307539 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,64E-03 0,06272103 ! response to protozoan GO:0001562 10 5 0,000 4,64E-03 0,06237064 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,64E-03 0,06202413 ! lymph vessel development GO:0001945 10 5 0,000 4,64E-03 0,06168146 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,64E-03 0,06134255 ! endochondral ossification GO:0001958 16 5 0,000 4,64E-03 0,06100734 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,64E-03 0,06067578 ! parathyroid gland development GO:0060017 13 5 0,000 4,64E-03 0,0603478 ! anagen GO:0042640 6 5 0,000 4,64E-03 0,06002335 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,64E-03 0,05970237 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,64E-03 0,05938481 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,64E-03 0,0590706 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,64E-03 0,0587597 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,64E-03 0,05845206 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,64E-03 0,05814762 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,64E-03 0,05784634 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,64E-03 0,05754816 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,64E-03 0,05725305 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,64E-03 0,05696094 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,64E-03 0,0566718 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,64E-03 0,05638558 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,64E-03 0,05610223 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,64E-03 0,05582172 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,64E-03 0,055544 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,64E-03 0,05526903 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,64E-03 0,05499677 ! histidine catabolic process GO:0006548 6 5 0,000 4,64E-03 0,05472718 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,64E-03 0,05446021 ! microvillus organization GO:0032528 7 5 0,000 4,64E-03 0,05419584 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,64E-03 0,05393403 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,64E-03 0,05367473 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,64E-03 0,05341791 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,64E-03 0,05316354 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,64E-03 0,05291158 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,64E-03 0,052662 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,64E-03 0,05241476 ! polyol catabolic process GO:0046174 7 5 0,000 4,64E-03 0,05216983 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,64E-03 0,05192718 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,64E-03 0,05168678 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,64E-03 0,05144859 ! muscle cell migration GO:0014812 8 5 0,000 4,64E-03 0,05121259 ! mitochondrial fission GO:0000266 8 5 0,000 4,64E-03 0,05097874 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,64E-03 0,05074702 ! mRNA transcription GO:0009299 9 5 0,000 4,64E-03 0,05051739 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,64E-03 0,05028984 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,64E-03 0,05006432 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,64E-03 0,04984082 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,64E-03 0,04961931 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,64E-03 0,04939975 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,64E-03 0,04918213 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,64E-03 0,04896642 ! response to food GO:0032094 6 5 0,000 4,64E-03 0,04875259 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,64E-03 0,04854063 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,64E-03 0,04833049 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,64E-03 0,04812217 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,64E-03 0,04791564 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,64E-03 0,04771087 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,64E-03 0,04750785 ! forebrain neuron development GO:0021884 13 5 0,000 4,64E-03 0,04730654 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,64E-03 0,04710694 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,64E-03 0,04690901 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,64E-03 0,04671274 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,64E-03 0,0465181 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,64E-03 0,04632508 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,64E-03 0,04613365 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,64E-03 0,0459438 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,64E-03 0,04575551 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,64E-03 0,04556875 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,64E-03 0,04538351 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,64E-03 0,04519977 ! basic amino acid transport GO:0015802 11 5 0,000 4,64E-03 0,04501752 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,64E-03 0,04483672 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,64E-03 0,04465738 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,64E-03 0,04447946 ! depyrimidination GO:0045008 10 5 0,000 4,64E-03 0,04430295 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,64E-03 0,04412784 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,64E-03 0,04395411 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,64E-03 0,04378174 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,64E-03 0,04361072 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,64E-03 0,04344103 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,64E-03 0,04327265 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,64E-03 0,04310557 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,64E-03 0,04293978 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,64E-03 0,04277526 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,64E-03 0,042612 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,64E-03 0,04244998 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,64E-03 0,04228918 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,64E-03 0,0421296 ! response to arsenic GO:0046685 10 5 0,000 4,64E-03 0,04197122 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,64E-03 0,04181402 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,64E-03 0,041658 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,64E-03 0,04150314 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,64E-03 0,04134942 ! response to cadmium ion GO:0046686 7 5 0,000 4,64E-03 0,04119684 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,64E-03 0,04104538 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,64E-03 0,04089503 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,64E-03 0,04074578 ! decidualization GO:0046697 11 5 0,000 4,64E-03 0,04059761 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,64E-03 0,04045052 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,64E-03 0,04030449 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,64E-03 0,04015951 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,64E-03 0,04001557 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,64E-03 0,03987266 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,64E-03 0,03973076 ! neural tube patterning GO:0021532 7 5 0,000 4,64E-03 0,03958987 ! embryonic cleavage GO:0040016 6 5 0,000 4,64E-03 0,03944998 ! peroxisome fission GO:0016559 5 5 0,000 4,64E-03 0,03931107 ! histone demethylation GO:0016577 10 5 0,000 4,64E-03 0,03917314 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,64E-03 0,03903617 ! mitotic recombination GO:0006312 9 5 0,000 4,64E-03 0,03890015 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,64E-03 0,03876508 ! metaphase plate congression GO:0051310 7 5 0,000 4,64E-03 0,03863095 ! regulation of sterol transport GO:0032371 7 5 0,000 4,64E-03 0,03849774 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,64E-03 0,03836544 ! enteric nervous system development GO:0048484 8 5 0,000 4,64E-03 0,03823405 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,64E-03 0,03810356 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,64E-03 0,03797396 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,64E-03 0,03784523 ! muscle cell proliferation GO:0033002 11 5 0,000 4,64E-03 0,03771738 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,64E-03 0,03759038 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,64E-03 0,03746424 ! plasminogen activation GO:0031639 5 5 0,000 4,64E-03 0,03733894 ! B cell homeostasis GO:0001782 13 5 0,000 4,64E-03 0,03721448 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,64E-03 0,03709084 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,64E-03 0,03696803 ! metaphase GO:0051323 8 5 0,000 4,64E-03 0,03684602 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,64E-03 0,03672482 ! cellular response to nutrient GO:0031670 8 5 0,000 4,64E-03 0,03660441 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,64E-03 0,03648478 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,64E-03 0,03636594 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,64E-03 0,03624787 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,64E-03 0,03613056 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,64E-03 0,03601401 ! response to redox state GO:0051775 5 5 0,000 4,64E-03 0,03589821 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,64E-03 0,03578315 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,64E-03 0,03566883 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,64E-03 0,03555524 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,64E-03 0,03544236 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,64E-03 0,0353302 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,64E-03 0,03521875 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,64E-03 0,035108 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,64E-03 0,03499794 ! striatum development GO:0021756 9 5 0,000 4,64E-03 0,03488857 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,64E-03 0,03477989 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,64E-03 0,03467188 ! glial cell migration GO:0008347 11 5 0,000 4,64E-03 0,03456453 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,64E-03 0,03445785 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,64E-03 0,03435183 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,64E-03 0,03424645 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,64E-03 0,03414172 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,64E-03 0,03403763 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,64E-03 0,03393418 ! neuroprotection GO:0043526 6 5 0,000 4,64E-03 0,03383135 ! neural plate development GO:0001840 8 5 0,000 4,64E-03 0,03372914 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,64E-03 0,03362754 ! regulation of sensory perception GO:0051931 7 5 0,000 4,64E-03 0,03352656 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,64E-03 0,03342618 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,64E-03 0,0333264 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,64E-03 0,03322721 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,64E-03 0,03312862 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,64E-03 0,0330306 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,64E-03 0,03293317 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,64E-03 0,03283631 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,64E-03 0,03274001 ! spindle assembly GO:0051225 6 5 0,000 4,64E-03 0,03264428 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,64E-03 0,03254911 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,64E-03 0,03245449 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,64E-03 0,03236042 ! drug metabolic process GO:0017144 6 5 0,000 4,64E-03 0,03226689 ! stem cell division GO:0017145 11 5 0,000 4,64E-03 0,0321739 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,64E-03 0,03208145 ! organ regeneration GO:0031100 7 5 0,000 4,64E-03 0,03198952 ! carnitine metabolic process GO:0009437 7 5 0,000 4,64E-03 0,03189813 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,64E-03 0,03180725 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,64E-03 0,03171689 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,566E-03 0,03793544 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,566E-03 0,03782828 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,566E-03 0,03772172 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,566E-03 0,03761576 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,566E-03 0,03751039 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,566E-03 0,03740562 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,566E-03 0,03730142 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,566E-03 0,03719781 ! sleep GO:0030431 13 6 0,000 5,566E-03 0,03709477 ! response to oxygen radical GO:0000305 11 6 0,000 5,566E-03 0,03699229 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,566E-03 0,03689039 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,566E-03 0,03678904 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,566E-03 0,03668825 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,566E-03 0,03658801 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,566E-03 0,03648831 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,566E-03 0,03638916 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,566E-03 0,03629054 ! forebrain regionalization GO:0021871 8 6 0,000 5,566E-03 0,03619246 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,566E-03 0,03609491 ! male meiosis GO:0007140 7 6 0,000 5,566E-03 0,03599788 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,566E-03 0,03590137 ! response to zinc ion GO:0010043 9 6 0,000 5,566E-03 0,03580537 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,566E-03 0,03570989 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,566E-03 0,03561492 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,566E-03 0,03552045 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,566E-03 0,03542648 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,566E-03 0,03533301 ! malate metabolic process GO:0006108 11 6 0,000 5,566E-03 0,03524003 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,566E-03 0,03514753 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,566E-03 0,03505552 ! protein refolding GO:0042026 15 6 0,000 5,566E-03 0,034964 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,566E-03 0,03487294 ! opsonization GO:0008228 8 6 0,000 5,566E-03 0,03478236 ! mating behavior GO:0007617 7 6 0,000 5,566E-03 0,03469225 ! neuron remodeling GO:0016322 15 6 0,000 5,566E-03 0,03460261 ! erythrocyte maturation GO:0043249 7 6 0,000 5,566E-03 0,03451343 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,566E-03 0,0344247 ! equilibrioception GO:0050957 14 6 0,000 5,566E-03 0,03433644 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,566E-03 0,03424862 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,566E-03 0,03416125 ! photoreceptor cell development GO:0042461 10 6 0,000 5,566E-03 0,03407433 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,566E-03 0,03398784 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,566E-03 0,0339018 ! response to interferon-gamma GO:0034341 15 6 0,000 5,566E-03 0,03381619 ! toxin metabolic process GO:0009404 11 6 0,000 5,566E-03 0,03373101 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,566E-03 0,03364626 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,566E-03 0,03356193 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,566E-03 0,03347803 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,566E-03 0,03339454 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,566E-03 0,03331147 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,566E-03 0,03322881 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,566E-03 0,03314656 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,566E-03 0,03306472 ! thymic T cell selection GO:0045061 12 6 0,000 5,566E-03 0,03298328 ! protein lipoylation GO:0009249 10 6 0,000 5,566E-03 0,03290224 ! cysteine metabolic process GO:0006534 10 6 0,000 5,566E-03 0,03282159 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,566E-03 0,03274135 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,566E-03 0,03266149 ! glutamate catabolic process GO:0006538 10 6 0,000 5,566E-03 0,03258202 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,566E-03 0,03250294 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,566E-03 0,03242424 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,566E-03 0,03234592 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,566E-03 0,03226798 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,566E-03 0,03219041 ! hyperosmotic response GO:0006972 9 6 0,000 5,566E-03 0,03211321 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,566E-03 0,03203639 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,566E-03 0,03195993 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,566E-03 0,03188383 ! urea metabolic process GO:0019627 7 6 0,000 5,566E-03 0,0318081 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,566E-03 0,03173273 ! neutrophil activation GO:0042119 8 6 0,000 5,566E-03 0,03165771 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,566E-03 0,03158304 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,566E-03 0,03150873 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,566E-03 0,03143477 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,566E-03 0,03136115 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,566E-03 0,03128787 ! neuron apoptosis GO:0051402 9 6 0,000 5,566E-03 0,03121494 ! nucleoside salvage GO:0043174 9 6 0,000 5,566E-03 0,03114235 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,566E-03 0,03107009 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,566E-03 0,03099817 ! T cell mediated immunity GO:0002456 16 6 0,000 5,566E-03 0,03092658 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,566E-03 0,03085532 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,566E-03 0,03078439 ! carnitine transport GO:0015879 10 6 0,000 5,566E-03 0,03071378 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,566E-03 0,0306435 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,566E-03 0,03057354 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,566E-03 0,0305039 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,566E-03 0,03043457 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,566E-03 0,03036556 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,566E-03 0,03029686 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,566E-03 0,03022847 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,566E-03 0,03016038 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,566E-03 0,03009261 ! establishment of spindle localization GO:0051293 12 6 0,000 5,566E-03 0,03002513 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,566E-03 0,02995796 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,566E-03 0,02989109 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,566E-03 0,02982452 ! neural nucleus development GO:0048857 14 6 0,000 5,566E-03 0,02975824 ! response to UV-C GO:0010225 11 6 0,000 5,566E-03 0,02969226 ! astrocyte development GO:0014002 15 6 0,000 5,566E-03 0,02962657 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,566E-03 0,02956117 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,566E-03 0,02949606 ! interaction with symbiont GO:0051702 13 6 0,000 5,566E-03 0,02943123 ! regulation of dendrite development GO:0050773 16 6 0,000 5,566E-03 0,02936669 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,566E-03 0,02930243 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,566E-03 0,02923845 ! response to copper ion GO:0046688 10 6 0,000 5,566E-03 0,02917475 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,566E-03 0,02911133 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,566E-03 0,02904818 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,566E-03 0,0289853 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,566E-03 0,0289227 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,566E-03 0,02886037 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,566E-03 0,0287983 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,566E-03 0,0287365 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,566E-03 0,02867497 ! hair follicle maturation GO:0048820 7 6 0,000 5,566E-03 0,0286137 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,566E-03 0,02855269 ! Schwann cell development GO:0014044 15 6 0,000 5,566E-03 0,02849194 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,566E-03 0,02843144 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,566E-03 0,02837121 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,566E-03 0,02831123 ! subpallium development GO:0021544 10 6 0,000 5,566E-03 0,0282515 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,566E-03 0,02819202 ! histone ubiquitination GO:0016574 8 6 0,000 5,566E-03 0,02813279 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,566E-03 0,02807382 ! maintenance of organ identity GO:0048496 9 6 0,000 5,566E-03 0,02801508 ! G2 phase GO:0051319 16 6 0,000 5,566E-03 0,0279566 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,566E-03 0,02789835 ! establishment of planar polarity GO:0001736 7 6 0,000 5,566E-03 0,02784035 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,566E-03 0,02778259 ! membrane to membrane docking GO:0022614 14 6 0,000 5,566E-03 0,02772507 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,566E-03 0,02766779 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,566E-03 0,02761074 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,566E-03 0,02755393 ! receptor internalization GO:0031623 10 6 0,000 5,566E-03 0,02749735 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,566E-03 0,027441 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,566E-03 0,02738489 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,566E-03 0,027329 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,566E-03 0,02727334 ! protein deubiquitination GO:0016579 14 6 0,000 5,566E-03 0,02721791 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,566E-03 0,0271627 ! protein destabilization GO:0031648 9 6 0,000 5,566E-03 0,02710771 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,566E-03 0,02705295 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,566E-03 0,02699841 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,566E-03 0,02694408 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,566E-03 0,02688998 ! progesterone metabolic process GO:0042448 10 6 0,000 5,566E-03 0,02683609 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,566E-03 0,02678242 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,566E-03 0,02672896 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,566E-03 0,02667572 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,566E-03 0,02662268 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,566E-03 0,02656986 ! determination of adult lifespan GO:0008340 15 6 0,000 5,566E-03 0,02651725 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,566E-03 0,02646484 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,566E-03 0,02641264 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,566E-03 0,02636065 ! catecholamine transport GO:0051937 9 6 0,000 5,566E-03 0,02630886 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,566E-03 0,02625727 ! sensory cilium assembly GO:0035058 10 6 0,000 5,566E-03 0,02620589 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,566E-03 0,02615471 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,566E-03 0,02610372 ! maternal placenta development GO:0001893 12 6 0,000 5,566E-03 0,02605294 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,566E-03 0,02600235 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,566E-03 0,02595196 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,566E-03 0,02590176 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,566E-03 0,02585176 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,566E-03 0,02580195 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,566E-03 0,02575233 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,566E-03 0,0257029 ! tRNA transcription GO:0009304 14 7 0,000 6,49E-03 0,02991586 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,49E-03 0,02985866 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,49E-03 0,02980168 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,49E-03 0,02974491 ! regulation of helicase activity GO:0051095 15 7 0,000 6,49E-03 0,02968836 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,49E-03 0,02963203 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,49E-03 0,02957591 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,49E-03 0,02952 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,49E-03 0,0294643 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,49E-03 0,02940881 ! prostate gland development GO:0030850 13 7 0,000 6,49E-03 0,02935353 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,49E-03 0,02929846 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,49E-03 0,02924359 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,49E-03 0,02918893 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,49E-03 0,02913448 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,49E-03 0,02908022 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,49E-03 0,02902617 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,49E-03 0,02897232 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,49E-03 0,02891867 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,49E-03 0,02886521 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,49E-03 0,02881196 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,49E-03 0,02875889 ! glycolipid transport GO:0046836 10 7 0,000 6,49E-03 0,02870603 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,49E-03 0,02865336 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,49E-03 0,02860088 ! neuron adhesion GO:0007158 12 7 0,000 6,49E-03 0,02854859 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,49E-03 0,0284965 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,49E-03 0,02844459 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,49E-03 0,02839287 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,49E-03 0,02834134 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,49E-03 0,02829 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,49E-03 0,02823884 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,49E-03 0,02818787 ! mRNA stabilization GO:0048255 18 7 0,000 6,49E-03 0,02813708 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,49E-03 0,02808647 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,49E-03 0,02803605 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,49E-03 0,02798581 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,49E-03 0,02793574 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,49E-03 0,02788586 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,49E-03 0,02783615 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,49E-03 0,02778662 ! lipoprotein transport GO:0042953 14 7 0,000 6,49E-03 0,02773726 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,49E-03 0,02768808 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,49E-03 0,02763908 ! rhythmic behavior GO:0007622 15 7 0,000 6,49E-03 0,02759025 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,49E-03 0,02754159 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,49E-03 0,0274931 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,49E-03 0,02744478 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,49E-03 0,02739663 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,49E-03 0,02734865 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,49E-03 0,02730084 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,49E-03 0,02725319 ! mechanosensory behavior GO:0007638 14 7 0,000 6,49E-03 0,02720571 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,49E-03 0,0271584 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,49E-03 0,02711125 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,49E-03 0,02706426 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,49E-03 0,02701744 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,49E-03 0,02697078 ! spinal cord patterning GO:0021511 13 7 0,000 6,49E-03 0,02692428 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,49E-03 0,02687793 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,49E-03 0,02683175 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,49E-03 0,02678573 ! adrenal gland development GO:0030325 17 7 0,000 6,49E-03 0,02673986 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,49E-03 0,02669415 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,49E-03 0,0266486 ! ovulation GO:0030728 9 7 0,000 6,49E-03 0,0266032 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,49E-03 0,02655796 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,49E-03 0,02651287 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,49E-03 0,02646793 ! microtubule nucleation GO:0007020 20 7 0,000 6,49E-03 0,02642315 ! proline biosynthetic process GO:0006561 10 7 0,000 6,49E-03 0,02637851 ! thyroid hormone generation GO:0006590 13 7 0,000 6,49E-03 0,02633403 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,49E-03 0,0262897 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,49E-03 0,02624551 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,49E-03 0,02620148 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,49E-03 0,02615759 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,49E-03 0,02611385 ! galactose metabolic process GO:0006012 13 7 0,000 6,49E-03 0,02607025 ! vesicle fusion GO:0006906 17 7 0,000 6,49E-03 0,0260268 ! response to dietary excess GO:0002021 8 7 0,000 6,49E-03 0,02598349 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,49E-03 0,02594033 ! intracellular pH reduction GO:0051452 11 7 0,000 6,49E-03 0,02589731 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,49E-03 0,02585444 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,49E-03 0,0258117 ! organ growth GO:0035265 15 7 0,000 6,49E-03 0,02576911 ! purine salvage GO:0043101 10 7 0,000 6,49E-03 0,02572666 ! nucleoside transport GO:0015858 8 7 0,000 6,49E-03 0,02568434 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,49E-03 0,02564217 ! parturition GO:0007567 14 7 0,000 6,49E-03 0,02560013 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,49E-03 0,02555823 ! rRNA modification GO:0000154 14 7 0,000 6,49E-03 0,02551647 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,49E-03 0,02547484 ! spindle checkpoint GO:0031577 15 7 0,000 6,49E-03 0,02543335 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,49E-03 0,025392 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,49E-03 0,02535078 ! macrophage differentiation GO:0030225 11 7 0,000 6,49E-03 0,02530969 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,49E-03 0,02526874 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,49E-03 0,02522792 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,49E-03 0,02518723 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,49E-03 0,02514667 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,49E-03 0,02510624 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,49E-03 0,02506594 ! fibrinolysis GO:0042730 10 7 0,000 6,49E-03 0,02502577 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,49E-03 0,02498573 ! eating behavior GO:0042755 7 7 0,000 6,49E-03 0,02494581 ! B cell lineage commitment GO:0002326 21 7 0,000 6,49E-03 0,02490603 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,49E-03 0,02486637 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,49E-03 0,02482684 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,49E-03 0,02478743 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,49E-03 0,02474815 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,49E-03 0,02470899 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,49E-03 0,02466995 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,49E-03 0,02463104 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,49E-03 0,02459225 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,49E-03 0,02455358 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,49E-03 0,02451504 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,49E-03 0,02447661 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,49E-03 0,02443831 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,49E-03 0,02440012 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,49E-03 0,02436206 ! regulation of meiosis GO:0040020 12 7 0,000 6,49E-03 0,02432411 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,49E-03 0,02428628 ! T cell lineage commitment GO:0002360 16 7 0,000 6,49E-03 0,02424857 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,49E-03 0,02421098 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,49E-03 0,0241735 ! oxygen homeostasis GO:0032364 12 7 0,000 6,49E-03 0,02413614 ! transcription termination GO:0006353 13 7 0,000 6,49E-03 0,02409889 ! response to tumor cell GO:0002347 13 7 0,000 6,49E-03 0,02406176 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,49E-03 0,02402474 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,49E-03 0,02398783 ! anaphase GO:0051322 17 7 0,000 6,49E-03 0,02395104 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,49E-03 0,02391436 ! axonal fasciculation GO:0007413 18 7 0,000 6,49E-03 0,0238778 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,49E-03 0,02384134 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,49E-03 0,023805 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,49E-03 0,02376877 ! diuresis GO:0030146 12 7 0,000 6,49E-03 0,02373264 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,49E-03 0,02369663 ! thiamin metabolic process GO:0006772 7 7 0,000 6,49E-03 0,02366073 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,49E-03 0,02362493 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,49E-03 0,02358924 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,49E-03 0,02355366 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,49E-03 0,02351819 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,49E-03 0,02348283 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,49E-03 0,02344757 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,49E-03 0,02341241 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,49E-03 0,02337736 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,49E-03 0,02334242 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,49E-03 0,02330758 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,49E-03 0,02327285 ! lymph node development GO:0048535 10 7 0,000 6,49E-03 0,02323821 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,49E-03 0,02320368 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,49E-03 0,02316926 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,49E-03 0,02313493 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,49E-03 0,02310071 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,49E-03 0,02306659 ! adult feeding behavior GO:0008343 9 7 0,000 6,49E-03 0,02303257 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,49E-03 0,02299864 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,49E-03 0,02296482 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,49E-03 0,0229311 ! muscle adaptation GO:0043500 14 7 0,000 6,49E-03 0,02289748 ! embryonic heart tube development GO:0035050 10 7 0,000 6,49E-03 0,02286395 ! retina homeostasis GO:0001895 12 7 0,000 6,49E-03 0,02283053 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,49E-03 0,0227972 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,49E-03 0,02276396 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,49E-03 0,02273083 ! protein prenylation GO:0018342 18 7 0,000 6,49E-03 0,02269779 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,49E-03 0,02266485 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,49E-03 0,022632 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,49E-03 0,02259925 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 7,414E-03 0,02577884 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 7,414E-03 0,02574164 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 7,414E-03 0,02570454 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 7,414E-03 0,02566756 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 7,414E-03 0,02563068 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,414E-03 0,02559391 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,414E-03 0,02555724 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 7,414E-03 0,02552068 ! neutral lipid catabolic process GO:0046461 13 8 0,000 7,414E-03 0,02548422 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 7,414E-03 0,02544787 ! meiotic prophase I GO:0007128 13 8 0,000 7,414E-03 0,02541162 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,414E-03 0,02537547 ! oligopeptide transport GO:0006857 15 8 0,000 7,414E-03 0,02533942 ! UTP metabolic process GO:0046051 8 8 0,000 7,414E-03 0,02530348 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 7,414E-03 0,02526764 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 7,414E-03 0,0252319 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 7,414E-03 0,02519626 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,414E-03 0,02516073 ! succinate metabolic process GO:0006105 14 8 0,000 7,414E-03 0,02512529 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,414E-03 0,02508995 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,414E-03 0,02505471 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 7,414E-03 0,02501957 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,414E-03 0,02498453 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 7,414E-03 0,02494959 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,414E-03 0,02491474 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,414E-03 0,02487999 ! ganglioside metabolic process GO:0001573 19 8 0,000 7,414E-03 0,02484534 ! reflex GO:0060004 16 8 0,000 7,414E-03 0,02481078 ! negative regulation of endocytosis GO:0045806 11 8 0,000 7,414E-03 0,02477633 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 7,414E-03 0,02474196 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,414E-03 0,02470769 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 7,414E-03 0,02467352 ! glycerolipid catabolic process GO:0046503 13 8 0,000 7,414E-03 0,02463944 ! hemoglobin metabolic process GO:0020027 13 8 0,000 7,414E-03 0,02460545 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,414E-03 0,02457156 ! pigment granule organization GO:0048753 16 8 0,000 7,414E-03 0,02453776 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,414E-03 0,02450406 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 7,414E-03 0,02447044 ! astrocyte differentiation GO:0048708 18 8 0,000 7,414E-03 0,02443692 ! histidine metabolic process GO:0006547 16 8 0,000 7,414E-03 0,02440349 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,414E-03 0,02437016 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 7,414E-03 0,02433691 ! glycine catabolic process GO:0006546 13 8 0,000 7,414E-03 0,02430375 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 7,414E-03 0,02427069 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 7,414E-03 0,02423771 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 7,414E-03 0,02420482 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 7,414E-03 0,02417202 ! regulation of pigmentation during development GO:0048070 24 8 0,000 7,414E-03 0,02413932 ! melanin metabolic process GO:0006582 15 8 0,000 7,414E-03 0,02410669 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 7,414E-03 0,02407416 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,414E-03 0,02404172 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,414E-03 0,02400936 ! macrophage activation GO:0042116 12 8 0,000 7,414E-03 0,02397709 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,414E-03 0,0239449 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,414E-03 0,02391281 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 7,414E-03 0,0238808 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,414E-03 0,02384887 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,414E-03 0,02381703 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 7,414E-03 0,02378527 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,414E-03 0,0237536 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 7,414E-03 0,02372201 ! osteoblast development GO:0002076 16 8 0,000 7,414E-03 0,02369051 ! positive regulation of vasodilation GO:0045909 13 8 0,000 7,414E-03 0,02365909 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,414E-03 0,02362775 ! negative regulation of translational initiation GO:0045947 10 8 0,000 7,414E-03 0,0235965 ! Schwann cell differentiation GO:0014037 19 8 0,000 7,414E-03 0,02356533 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 7,414E-03 0,02353424 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,414E-03 0,02350323 ! response to UV-B GO:0010224 16 8 0,000 7,414E-03 0,02347231 ! protein targeting to vacuole GO:0006623 12 8 0,000 7,414E-03 0,02344146 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,414E-03 0,0234107 ! intermediate filament organization GO:0045109 12 8 0,000 7,414E-03 0,02338002 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 7,414E-03 0,02334942 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 7,414E-03 0,02331889 ! cellular extravasation GO:0045123 12 8 0,000 7,414E-03 0,02328845 ! cardiac muscle cell development GO:0055013 13 8 0,000 7,414E-03 0,02325809 ! regulation of circadian rhythm GO:0042752 16 8 0,000 7,414E-03 0,0232278 ! response to antibiotic GO:0046677 11 8 0,000 7,414E-03 0,0231976 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 7,414E-03 0,02316747 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 7,414E-03 0,02313742 ! response to tropane GO:0014073 15 8 0,000 7,414E-03 0,02310745 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 7,414E-03 0,02307756 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 7,414E-03 0,02304774 ! melanosome transport GO:0032402 13 8 0,000 7,414E-03 0,02301801 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 7,414E-03 0,02298834 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 7,414E-03 0,02295876 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,414E-03 0,02292925 ! mast cell activation GO:0045576 14 8 0,000 7,414E-03 0,02289981 ! multicellular organismal aging GO:0010259 18 8 0,000 7,414E-03 0,02287045 ! dendrite morphogenesis GO:0048813 13 8 0,000 7,414E-03 0,02284117 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 7,414E-03 0,02281196 ! nucleosome disassembly GO:0006337 14 8 0,000 7,414E-03 0,02278283 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,414E-03 0,02275377 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 7,414E-03 0,02272478 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,414E-03 0,02269587 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,414E-03 0,02266703 ! establishment of chromosome localization GO:0051303 12 8 0,000 7,414E-03 0,02263827 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 7,414E-03 0,02260957 ! intracellular lipid transport GO:0032365 13 8 0,000 7,414E-03 0,02258095 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,414E-03 0,02255241 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,414E-03 0,02252393 ! regulation of macrophage activation GO:0043030 15 8 0,000 7,414E-03 0,02249553 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 7,414E-03 0,0224672 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,414E-03 0,02243894 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 7,414E-03 0,02241075 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 7,414E-03 0,02238263 ! hormone catabolic process GO:0042447 17 8 0,000 7,414E-03 0,02235458 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,414E-03 0,0223266 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 7,414E-03 0,02229869 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 7,414E-03 0,02227085 ! ATP catabolic process GO:0006200 11 8 0,000 7,414E-03 0,02224308 ! blastocyst growth GO:0001832 19 8 0,000 7,414E-03 0,02221539 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,414E-03 0,02218775 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,414E-03 0,02216019 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 7,414E-03 0,0221327 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,414E-03 0,02210527 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,414E-03 0,02207791 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 7,414E-03 0,02205062 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 7,414E-03 0,0220234 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 7,414E-03 0,02199624 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 7,414E-03 0,02196916 ! amino sugar catabolic process GO:0046348 10 8 0,000 7,414E-03 0,02194213 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 7,414E-03 0,02191518 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,414E-03 0,02188829 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,414E-03 0,02186146 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,414E-03 0,02183471 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,414E-03 0,02180801 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,414E-03 0,02178138 ! NAD biosynthetic process GO:0009435 13 8 0,000 7,414E-03 0,02175482 ! regulation of developmental growth GO:0048638 15 9 0,000 8,337E-03 0,02443342 ! axon extension GO:0048675 15 9 0,000 8,337E-03 0,02440369 ! autophagic vacuole formation GO:0000045 15 9 0,000 8,337E-03 0,02437404 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,337E-03 0,02434446 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 8,337E-03 0,02431495 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 8,337E-03 0,02428551 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,337E-03 0,02425615 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 8,337E-03 0,02422685 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 8,337E-03 0,02419763 ! cell proliferation in forebrain GO:0021846 15 9 0,000 8,337E-03 0,02416848 ! phosphate transport GO:0006817 19 9 0,000 8,337E-03 0,02413939 ! reproductive behavior GO:0019098 19 9 0,000 8,337E-03 0,02411038 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,337E-03 0,02408143 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 8,337E-03 0,02405256 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,337E-03 0,02402375 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 8,337E-03 0,02399502 ! GTP metabolic process GO:0046039 9 9 0,000 8,337E-03 0,02396635 ! RNA methylation GO:0001510 15 9 0,000 8,337E-03 0,02393775 ! elastic fiber assembly GO:0048251 15 9 0,000 8,337E-03 0,02390922 ! induction of positive chemotaxis GO:0050930 15 9 0,000 8,337E-03 0,02388076 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 8,337E-03 0,02385236 ! artery development GO:0060840 24 9 0,000 8,337E-03 0,02382403 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 8,337E-03 0,02379577 ! regulation of glycolysis GO:0006110 21 9 0,000 8,337E-03 0,02376758 ! cerebral cortex cell migration GO:0021795 15 9 0,000 8,337E-03 0,02373945 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 8,337E-03 0,02371139 ! chemosensory behavior GO:0007635 20 9 0,000 8,337E-03 0,02368339 ! microtubule bundle formation GO:0001578 21 9 0,000 8,337E-03 0,02365547 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,337E-03 0,0236276 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 8,337E-03 0,02359981 ! leukocyte degranulation GO:0043299 16 9 0,000 8,337E-03 0,02357207 ! bile acid and bile salt transport GO:0015721 13 9 0,000 8,337E-03 0,02354441 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 8,337E-03 0,02351681 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 8,337E-03 0,02348927 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,337E-03 0,0234618 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,337E-03 0,02343439 ! protein targeting to ER GO:0045047 22 9 0,000 8,337E-03 0,02340704 ! ceramide biosynthetic process GO:0046513 19 9 0,000 8,337E-03 0,02337976 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 8,337E-03 0,02335254 ! T cell selection GO:0045058 23 9 0,000 8,337E-03 0,02332539 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 8,337E-03 0,0232983 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 8,337E-03 0,02327127 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,337E-03 0,02324431 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 8,337E-03 0,0232174 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,337E-03 0,02319056 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,337E-03 0,02316378 ! mannose metabolic process GO:0006013 13 9 0,000 8,337E-03 0,02313706 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 8,337E-03 0,02311041 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 8,337E-03 0,02308382 ! Rac protein signal transduction GO:0016601 17 9 0,000 8,337E-03 0,02305728 ! receptor clustering GO:0043113 18 9 0,000 8,337E-03 0,02303081 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 8,337E-03 0,0230044 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,337E-03 0,02297805 ! ruffle organization GO:0031529 15 9 0,000 8,337E-03 0,02295176 ! retinol metabolic process GO:0042572 18 9 0,000 8,337E-03 0,02292553 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 8,337E-03 0,02289936 ! behavioral fear response GO:0001662 22 9 0,000 8,337E-03 0,02287324 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 8,337E-03 0,02284719 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 8,337E-03 0,0228212 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 8,337E-03 0,02279527 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 8,337E-03 0,02276939 ! protein heterooligomerization GO:0051291 16 9 0,000 8,337E-03 0,02274358 ! oligodendrocyte development GO:0014003 10 9 0,000 8,337E-03 0,02271782 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 8,337E-03 0,02269212 ! segment specification GO:0007379 13 9 0,000 8,337E-03 0,02266648 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,337E-03 0,0226409 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 8,337E-03 0,02261537 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,337E-03 0,0225899 ! response to amine stimulus GO:0014075 13 9 0,000 8,337E-03 0,02256449 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,337E-03 0,02253914 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 8,337E-03 0,02251384 ! erythrocyte development GO:0048821 15 9 0,000 8,337E-03 0,0224886 ! gas homeostasis GO:0033483 16 9 0,000 8,337E-03 0,02246342 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,337E-03 0,02243829 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 8,337E-03 0,02241322 ! renal water homeostasis GO:0003091 14 9 0,000 8,337E-03 0,02238821 ! postreplication repair GO:0006301 22 9 0,000 8,337E-03 0,02236325 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 8,337E-03 0,02233835 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 8,337E-03 0,0223135 ! icosanoid secretion GO:0032309 15 9 0,000 8,337E-03 0,02228871 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 8,337E-03 0,02226397 ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,337E-03 0,02223929 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 8,337E-03 0,02221466 ! regulation of cell division GO:0051302 15 9 0,000 8,337E-03 0,02219008 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 8,337E-03 0,02216556 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,337E-03 0,0221411 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,337E-03 0,02211669 ! sterol catabolic process GO:0016127 11 9 0,000 8,337E-03 0,02209233 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,337E-03 0,02206803 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 8,337E-03 0,02204378 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 8,337E-03 0,02201958 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 8,337E-03 0,02199543 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 8,337E-03 0,02197134 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 8,337E-03 0,0219473 ! musculoskeletal movement GO:0050881 14 9 0,000 8,337E-03 0,02192332 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 8,337E-03 0,02189938 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 8,337E-03 0,0218755 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,337E-03 0,02185167 ! purine base metabolic process GO:0006144 21 9 0,000 8,337E-03 0,02182789 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 8,337E-03 0,02180417 ! pigment granule transport GO:0051904 17 9 0,000 8,337E-03 0,02178049 ! regulation of fibrinolysis GO:0051917 16 9 0,000 8,337E-03 0,02175687 ! regulation of telomere maintenance GO:0032204 14 9 0,000 8,337E-03 0,0217333 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 8,337E-03 0,02170978 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,337E-03 0,02168631 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,337E-03 0,02166289 ! mitochondrion localization GO:0051646 15 9 0,000 8,337E-03 0,02163952 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 9,26E-03 0,02400725 ! negative regulation of blood pressure GO:0045776 26 10 0,000 9,26E-03 0,0239814 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 9,26E-03 0,02395562 ! synapsis GO:0007129 13 10 0,000 9,26E-03 0,02392989 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 9,26E-03 0,02390421 ! N-glycan processing GO:0006491 20 10 0,000 9,26E-03 0,02387859 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 9,26E-03 0,02385302 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 9,26E-03 0,02382751 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 9,26E-03 0,02380206 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 9,26E-03 0,02377665 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 9,26E-03 0,02375131 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 9,26E-03 0,02372601 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 9,26E-03 0,02370077 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 9,26E-03 0,02367558 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 9,26E-03 0,02365045 ! androgen metabolic process GO:0008209 17 10 0,000 9,26E-03 0,02362537 ! phospholipid efflux GO:0033700 16 10 0,000 9,26E-03 0,02360034 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 9,26E-03 0,02357537 ! positive regulation of heart contraction GO:0045823 16 10 0,000 9,26E-03 0,02355045 ! lung alveolus development GO:0048286 26 10 0,000 9,26E-03 0,02352558 ! pathogenesis GO:0009405 13 10 0,000 9,26E-03 0,02350076 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 9,26E-03 0,023476 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 9,26E-03 0,02345129 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 9,26E-03 0,02342663 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 9,26E-03 0,02340202 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 9,26E-03 0,02337747 ! endoderm development GO:0007492 16 10 0,000 9,26E-03 0,02335296 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 9,26E-03 0,02332851 ! arginine catabolic process GO:0006527 13 10 0,000 9,26E-03 0,02330411 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 9,26E-03 0,02327975 ! proline metabolic process GO:0006560 13 10 0,000 9,26E-03 0,02325545 ! glucan biosynthetic process GO:0009250 14 10 0,000 9,26E-03 0,0232312 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 9,26E-03 0,023207 ! polyamine biosynthetic process GO:0006596 12 10 0,000 9,26E-03 0,02318286 ! V(D)J recombination GO:0033151 28 10 0,000 9,26E-03 0,02315876 ! reverse cholesterol transport GO:0043691 16 10 0,000 9,26E-03 0,02313471 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 9,26E-03 0,02311071 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 9,26E-03 0,02308676 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 9,26E-03 0,02306286 ! regulation of sodium ion transport GO:0002028 21 10 0,000 9,26E-03 0,02303901 ! multicellular organism growth GO:0035264 18 10 0,000 9,26E-03 0,02301521 ! phagocytosis, engulfment GO:0006911 28 10 0,000 9,26E-03 0,02299146 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 9,26E-03 0,02296776 ! epithelial cell development GO:0002064 20 10 0,000 9,26E-03 0,0229441 ! lens development in camera-type eye GO:0002088 16 10 0,000 9,26E-03 0,0229205 ! retinoic acid metabolic process GO:0042573 14 10 0,000 9,26E-03 0,02289694 ! macroautophagy GO:0016236 17 10 0,000 9,26E-03 0,02287343 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 9,26E-03 0,02284997 ! positive regulation of translational initiation GO:0045948 11 10 0,000 9,26E-03 0,02282656 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 9,26E-03 0,0228032 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 9,26E-03 0,02277988 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 9,26E-03 0,02275661 ! copper ion homeostasis GO:0055070 13 10 0,000 9,26E-03 0,02273339 ! regulation of bone resorption GO:0045124 25 10 0,000 9,26E-03 0,02271022 ! regulation of gliogenesis GO:0014013 23 10 0,000 9,26E-03 0,02268709 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 9,26E-03 0,02266401 ! alpha-beta T cell activation GO:0046631 23 10 0,000 9,26E-03 0,02264098 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 9,26E-03 0,02261799 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 9,26E-03 0,02259506 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 9,26E-03 0,02257216 ! blastoderm segmentation GO:0007350 18 10 0,000 9,26E-03 0,02254932 ! response to dsRNA GO:0043331 20 10 0,000 9,26E-03 0,02252652 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 9,26E-03 0,02250376 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 9,26E-03 0,02248105 ! melanosome localization GO:0032400 16 10 0,000 9,26E-03 0,02245839 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 9,26E-03 0,02243578 ! regulation of B cell differentiation GO:0045577 19 10 0,000 9,26E-03 0,0224132 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 9,26E-03 0,02239068 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 9,26E-03 0,0223682 ! mRNA cleavage GO:0006379 17 10 0,000 9,26E-03 0,02234576 ! protein sumoylation GO:0016925 15 10 0,000 9,26E-03 0,02232337 ! hindbrain morphogenesis GO:0021575 19 10 0,000 9,26E-03 0,02230103 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 9,26E-03 0,02227872 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 9,26E-03 0,02225647 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 9,26E-03 0,02223426 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 9,26E-03 0,02221209 ! salivary gland development GO:0007431 27 10 0,000 9,26E-03 0,02218996 ! prophase GO:0051324 15 10 0,000 9,26E-03 0,02216789 ! negative regulation of neurological system process GO:0031645 19 10 0,000 9,26E-03 0,02214585 ! apical protein localization GO:0045176 15 10 0,000 9,26E-03 0,02212386 ! ubiquinone metabolic process GO:0006743 15 10 0,000 9,26E-03 0,02210191 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 9,26E-03 0,02208 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 9,26E-03 0,02205814 ! midbrain development GO:0030901 13 10 0,000 9,26E-03 0,02203633 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 9,26E-03 0,02201455 ! methionine biosynthetic process GO:0009086 19 10 0,000 9,26E-03 0,02199282 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 9,26E-03 0,02197113 ! quaternary ammonium group transport GO:0015697 21 10 0,000 9,26E-03 0,02194948 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 9,26E-03 0,02192788 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 9,26E-03 0,02190632 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 9,26E-03 0,0218848 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 9,26E-03 0,02186332 ! establishment of pigment granule localization GO:0051905 18 10 0,000 9,26E-03 0,02184189 ! blastocyst formation GO:0001825 17 10 0,000 9,26E-03 0,02182049 ! cerebellar cortex development GO:0021695 15 10 0,000 9,26E-03 0,02179914 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 9,26E-03 0,02177783 ! activation of innate immune response GO:0002218 12 10 0,000 9,26E-03 0,02175657 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 9,26E-03 0,02173534 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 9,26E-03 0,02171416 ! response to nicotine GO:0035094 20 10 0,000 9,26E-03 0,02169301 ! establishment of cell polarity GO:0030010 16 10 0,000 9,26E-03 0,02167191 ! negative regulation of immune effector process GO:0002698 20 10 0,000 9,26E-03 0,02165085 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 9,26E-03 0,02162983 ! localization within membrane GO:0051668 20 10 0,000 9,26E-03 0,02160885 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01018106 0,02373607 ! respiratory burst GO:0045730 17 11 0,000 0,01018106 0,02371309 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01018106 0,02369016 ! neuron fate specification GO:0048665 17 11 0,000 0,01018106 0,02366727 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01018106 0,02364443 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01018106 0,02362162 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01018106 0,02359887 ! thyroid gland development GO:0030878 26 11 0,000 0,01018106 0,02357615 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01018106 0,02355348 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01018106 0,02353086 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01018106 0,02350828 ! response to pain GO:0048265 24 11 0,000 0,01018106 0,02348574 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01018106 0,02346324 ! T cell proliferation GO:0042098 26 11 0,000 0,01018106 0,02344079 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01018106 0,02341838 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01018106 0,02339601 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01018106 0,02337369 ! bone resorption GO:0045453 16 11 0,000 0,01018106 0,02335141 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01018106 0,02332917 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01018106 0,02330697 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01018106 0,02328481 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01018106 0,0232627 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01018106 0,02324063 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01018106 0,0232186 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01018106 0,02319661 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01018106 0,02317467 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01018106 0,02315276 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01018106 0,0231309 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01018106 0,02310908 ! lipid digestion GO:0044241 18 11 0,000 0,01018106 0,0230873 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01018106 0,02306556 ! UV protection GO:0009650 19 11 0,000 0,01018106 0,02304386 ! adult heart development GO:0007512 14 11 0,000 0,01018106 0,0230222 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01018106 0,02300059 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01018106 0,02297901 ! temperature homeostasis GO:0001659 17 11 0,000 0,01018106 0,02295747 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01018106 0,02293598 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01018106 0,02291452 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01018106 0,02289311 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01018106 0,02287173 ! regulation of organ growth GO:0046620 13 11 0,000 0,01018106 0,0228504 ! pigment granule localization GO:0051875 20 11 0,000 0,01018106 0,0228291 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01018106 0,02280784 ! vasoconstriction GO:0042310 18 11 0,000 0,01018106 0,02278663 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01018106 0,02276545 ! embryonic axis specification GO:0000578 18 11 0,000 0,01018106 0,02274431 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01018106 0,02272321 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01018106 0,02270215 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01018106 0,02268113 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01018106 0,02266015 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01018106 0,02263921 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01018106 0,02261831 ! zymogen activation GO:0031638 15 11 0,000 0,01018106 0,02259744 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01018106 0,02257661 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01018106 0,02255582 ! nucleosome positioning GO:0016584 15 11 0,000 0,01018106 0,02253507 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01018106 0,02251436 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01018106 0,02249369 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01018106 0,02247305 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01018106 0,02245245 ! acid secretion GO:0046717 18 11 0,000 0,01018106 0,02243189 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01018106 0,02241137 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01018106 0,02239088 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01018106 0,02237043 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01018106 0,02235002 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01018106 0,02232965 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01018106 0,02230931 ! cholesterol efflux GO:0033344 19 11 0,000 0,01018106 0,02228901 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01018106 0,02226875 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01018106 0,02224852 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01018106 0,02222833 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01018106 0,02220818 ! embryonic gut development GO:0048566 15 11 0,000 0,01018106 0,02218807 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01018106 0,02216799 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01018106 0,02214794 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01018106 0,02212794 ! defense response to fungus GO:0050832 13 11 0,000 0,01018106 0,02210796 ! developmental induction GO:0031128 19 11 0,000 0,01018106 0,02208803 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01018106 0,02206813 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01018106 0,02204827 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01018106 0,02202844 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01018106 0,02200865 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01018106 0,02198889 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01018106 0,02196917 ! nucleus localization GO:0051647 19 11 0,000 0,01018106 0,02194948 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01018106 0,02192983 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01110164 0,02389136 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01110164 0,02387001 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01110164 0,02384869 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01110164 0,02382742 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01110164 0,02380618 ! virus-host interaction GO:0019048 29 12 0,000 0,01110164 0,02378498 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01110164 0,02376382 ! cartilage condensation GO:0001502 20 12 0,000 0,01110164 0,0237427 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01110164 0,02372161 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01110164 0,02370056 ! protein complex disassembly GO:0043241 27 12 0,000 0,01110164 0,02367955 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01110164 0,02365858 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01110164 0,02363764 ! hippocampus development GO:0021766 26 12 0,000 0,01110164 0,02361674 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01110164 0,02359588 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01110164 0,02357505 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01110164 0,02355426 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01110164 0,02353351 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01110164 0,0235128 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01110164 0,02349212 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01110164 0,02347147 ! drug transport GO:0015893 16 12 0,000 0,01110164 0,02345087 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01110164 0,02343029 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01110164 0,02340976 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01110164 0,02338926 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01110164 0,0233688 ! focal adhesion formation GO:0048041 35 12 0,000 0,01110164 0,02334837 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01110164 0,02332798 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01110164 0,02330762 ! forebrain cell migration GO:0021885 21 12 0,000 0,01110164 0,0232873 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01110164 0,02326702 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01110164 0,02324677 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01110164 0,02322655 ! entry into host cell GO:0030260 32 12 0,000 0,01110164 0,02320637 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01110164 0,02318623 ! monoamine transport GO:0015844 18 12 0,000 0,01110164 0,02316612 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01110164 0,02314604 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01110164 0,023126 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01110164 0,023106 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01110164 0,02308603 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01110164 0,02306609 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01110164 0,02304619 ! protein homotetramerization GO:0051289 21 12 0,000 0,01110164 0,02302632 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01110164 0,02300649 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01110164 0,02298669 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01110164 0,02296693 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01110164 0,0229472 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01110164 0,0229275 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01110164 0,02290784 ! cranial nerve development GO:0021545 20 12 0,000 0,01110164 0,02288821 ! fucose catabolic process GO:0019317 22 12 0,000 0,01110164 0,02286861 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01110164 0,02284905 ! histone acetylation GO:0016573 26 12 0,000 0,01110164 0,02282952 ! histone methylation GO:0016571 26 12 0,000 0,01110164 0,02281002 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01110164 0,02279056 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01110164 0,02277113 ! gland morphogenesis GO:0022612 29 12 0,000 0,01110164 0,02275173 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01110164 0,02273237 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01110164 0,02271304 ! T cell homeostasis GO:0043029 25 12 0,000 0,01110164 0,02269374 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01110164 0,02267448 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01110164 0,02265525 ! spleen development GO:0048536 22 12 0,000 0,01110164 0,02263605 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01110164 0,02261688 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01110164 0,02259775 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01110164 0,02257864 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01110164 0,02255957 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01110164 0,02254054 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01110164 0,02252153 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01110164 0,02250256 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01110164 0,02248362 ! response to cold GO:0009409 17 12 0,000 0,01110164 0,02246471 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01110164 0,02244583 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01110164 0,02242698 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01202139 0,02426465 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01202139 0,02424431 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01202139 0,024224 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01202139 0,02420373 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01202139 0,0241835 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01202139 0,02416329 ! lipid localization GO:0010876 28 13 0,000 0,01202139 0,02414312 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01202139 0,02412299 ! organelle fusion GO:0048284 32 13 0,000 0,01202139 0,02410288 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01202139 0,02408281 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01202139 0,02406278 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01202139 0,02404278 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01202139 0,02402281 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01202139 0,02400287 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01202139 0,02398297 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01202139 0,0239631 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01202139 0,02394326 ! methionine metabolic process GO:0006555 27 13 0,000 0,01202139 0,02392346 ! plasma membrane organization GO:0007009 24 13 0,000 0,01202139 0,02390369 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01202139 0,02388395 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01202139 0,02386424 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01202139 0,02384457 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01202139 0,02382493 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01202139 0,02380532 ! response to X-ray GO:0010165 25 13 0,000 0,01202139 0,02378574 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01202139 0,0237662 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01202139 0,02374668 ! exocrine system development GO:0035272 32 13 0,000 0,01202139 0,0237272 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01202139 0,02370775 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01202139 0,02368834 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01202139 0,02366895 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01202139 0,0236496 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01202139 0,02363028 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01202139 0,02361099 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01202139 0,02359173 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01202139 0,0235725 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01202139 0,02355331 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01202139 0,02353414 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01202139 0,02351501 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01202139 0,02349591 ! ribosome assembly GO:0042255 17 13 0,000 0,01202139 0,02347683 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01202139 0,02345779 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01202139 0,02343878 ! chromatin silencing GO:0006342 26 13 0,000 0,01202139 0,02341981 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01202139 0,02340086 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01202139 0,02338194 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01202139 0,02336305 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01202139 0,0233442 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01202139 0,02332537 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01202139 0,02330658 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01202139 0,02328781 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01202139 0,02326908 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01202139 0,02325037 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01202139 0,0232317 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01202139 0,02321305 ! embryonic placenta development GO:0001892 23 13 0,000 0,01202139 0,02319444 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01202139 0,02317585 ! insulin secretion GO:0030073 23 13 0,000 0,01202139 0,02315729 ! actin filament polymerization GO:0030041 24 13 0,000 0,01202139 0,02313877 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01202139 0,02312027 ! acrosome reaction GO:0007340 18 13 0,000 0,01202139 0,02310181 ! rRNA transcription GO:0009303 25 14 0,000 0,01294032 0,02484789 ! lactation GO:0007595 26 14 0,000 0,01294032 0,02482807 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01294032 0,02480829 ! reproductive cellular process GO:0048610 20 14 0,000 0,01294032 0,02478854 ! tRNA modification GO:0006400 20 14 0,000 0,01294032 0,02476882 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01294032 0,02474913 ! regulation of S phase GO:0033261 23 14 0,000 0,01294032 0,02472947 ! water transport GO:0006833 21 14 0,000 0,01294032 0,02470984 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01294032 0,02469025 ! non-recombinational repair GO:0000726 25 14 0,000 0,01294032 0,02467068 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01294032 0,02465115 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01294032 0,02463165 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01294032 0,02461217 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01294032 0,02459273 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01294032 0,02457332 ! palate development GO:0060021 31 14 0,000 0,01294032 0,02455394 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01294032 0,02453459 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01294032 0,02451528 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01294032 0,02449599 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01294032 0,02447673 ! arginine metabolic process GO:0006525 17 14 0,000 0,01294032 0,0244575 ! regulation of heart rate GO:0002027 24 14 0,000 0,01294032 0,02443831 ! organic alcohol transport GO:0015850 29 14 0,000 0,01294032 0,02441914 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01294032 0,0244 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01294032 0,02438089 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01294032 0,02436182 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01294032 0,02434277 ! L-amino acid transport GO:0015807 30 14 0,000 0,01294032 0,02432375 ! bone mineralization GO:0030282 17 14 0,000 0,01294032 0,02430476 ! stem cell development GO:0048864 43 14 0,000 0,01294032 0,0242858 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01294032 0,02426688 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01294032 0,02424798 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01294032 0,02422911 ! cerebellum development GO:0021549 21 14 0,000 0,01294032 0,02421027 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01294032 0,02419145 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01294032 0,02417267 ! response to gamma radiation GO:0010332 28 14 0,000 0,01294032 0,02415392 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01294032 0,02413519 ! cofactor transport GO:0051181 26 14 0,000 0,01294032 0,0241165 ! NADP metabolic process GO:0006739 24 14 0,000 0,01294032 0,02409783 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01294032 0,0240792 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01294032 0,02406059 ! intestinal absorption GO:0050892 25 14 0,000 0,01294032 0,02404201 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01294032 0,02402346 ! oxygen transport GO:0015671 21 14 0,000 0,01294032 0,02400494 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01294032 0,02398644 ! male genitalia development GO:0030539 24 14 0,000 0,01294032 0,02396798 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01294032 0,02394954 ! regulation of axon extension GO:0030516 37 14 0,000 0,01294032 0,02393113 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01294032 0,02391275 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01385842 0,02558968 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01385842 0,02557006 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01385842 0,02555047 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01385842 0,0255309 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01385842 0,02551137 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01385842 0,02549186 ! copper ion transport GO:0006825 20 15 0,000 0,01385842 0,02547239 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01385842 0,02545295 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01385842 0,02543353 ! sulfate transport GO:0008272 23 15 0,000 0,01385842 0,02541414 ! response to cAMP GO:0051591 22 15 0,000 0,01385842 0,02539479 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01385842 0,02537546 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01385842 0,02535617 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01385842 0,0253369 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01385842 0,02531766 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01385842 0,02529845 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01385842 0,02527927 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01385842 0,02526012 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01385842 0,025241 ! pituitary gland development GO:0021983 29 15 0,000 0,01385842 0,0252219 ! vesicle coating GO:0006901 33 15 0,000 0,01385842 0,02520284 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01385842 0,02518381 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01385842 0,0251648 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01385842 0,02514582 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01385842 0,02512687 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01385842 0,02510795 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01385842 0,02508906 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01385842 0,02507019 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01385842 0,02505136 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01385842 0,02503255 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01385842 0,02501377 ! histone deacetylation GO:0016575 20 15 0,000 0,01385842 0,02499502 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01385842 0,0249763 ! tissue regeneration GO:0042246 26 15 0,000 0,01385842 0,0249576 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01385842 0,02493894 ! water homeostasis GO:0030104 27 15 0,000 0,01385842 0,0249203 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01385842 0,02490169 ! muscle maintenance GO:0046716 26 15 0,000 0,01385842 0,0248831 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01385842 0,02486455 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01385842 0,02484602 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01385842 0,02482752 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01385842 0,02480905 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01385842 0,0247906 ! cell killing GO:0001906 29 15 0,000 0,01385842 0,02477218 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01385842 0,02475379 ! detection of bacterium GO:0016045 18 15 0,000 0,01385842 0,02473543 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01385842 0,02471709 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01385842 0,02469878 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01385842 0,0246805 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01385842 0,02466225 ! peptide hormone processing GO:0016486 23 15 0,000 0,01385842 0,02464402 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0147757 0,02625579 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0147757 0,02623641 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0147757 0,02621706 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0147757 0,02619774 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0147757 0,02617845 ! bone remodeling GO:0046849 27 16 0,000 0,0147757 0,02615919 ! filopodium assembly GO:0046847 32 16 0,000 0,0147757 0,02613995 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0147757 0,02612074 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0147757 0,02610157 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0147757 0,02608242 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0147757 0,02606329 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0147757 0,0260442 ! startle response GO:0001964 28 16 0,000 0,0147757 0,02602513 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0147757 0,0260061 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0147757 0,02598709 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0147757 0,0259681 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0147757 0,02594915 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0147757 0,02593022 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0147757 0,02591132 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0147757 0,02589245 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0147757 0,02587361 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0147757 0,02585479 ! response to osmotic stress GO:0006970 25 16 0,000 0,0147757 0,025836 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0147757 0,02581724 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0147757 0,0257985 ! fructose metabolic process GO:0006000 25 16 0,000 0,0147757 0,02577979 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0147757 0,02576111 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,0147757 0,02574246 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0147757 0,02572383 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0147757 0,02570523 ! axon cargo transport GO:0008088 43 16 0,000 0,0147757 0,02568666 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0147757 0,02566811 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0147757 0,02564959 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0147757 0,0256311 ! DNA replication initiation GO:0006270 27 16 0,000 0,0147757 0,02561263 ! neuron recognition GO:0008038 35 16 0,000 0,0147757 0,02559419 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0147757 0,02557578 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0147757 0,02555739 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0147757 0,02553903 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0147757 0,0255207 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0147757 0,02550239 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0147757 0,02548411 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0147757 0,02546586 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0147757 0,02544763 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0147757 0,02542942 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0147757 0,02541125 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0147757 0,0253931 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,0147757 0,02537497 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0147757 0,02535687 ! defense response to virus GO:0051607 37 16 0,000 0,0147757 0,0253388 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01569216 0,02689126 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01569216 0,02687212 ! metencephalon development GO:0022037 30 17 0,000 0,01569216 0,02685301 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01569216 0,02683392 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01569216 0,02681487 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01569216 0,02679583 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01569216 0,02677683 ! signal complex assembly GO:0007172 41 17 0,000 0,01569216 0,02675785 ! endothelial cell migration GO:0043542 28 17 0,000 0,01569216 0,0267389 ! inositol metabolic process GO:0006020 28 17 0,000 0,01569216 0,02671998 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01569216 0,02670108 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01569216 0,02668221 ! glial cell development GO:0021782 27 17 0,000 0,01569216 0,02666337 ! limbic system development GO:0021761 36 17 0,000 0,01569216 0,02664455 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01569216 0,02662576 ! adult walking behavior GO:0007628 33 17 0,000 0,01569216 0,026607 ! heart looping GO:0001947 30 17 0,000 0,01569216 0,02658826 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01569216 0,02656955 ! myoblast differentiation GO:0045445 45 17 0,000 0,01569216 0,02655086 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01569216 0,02653221 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01569216 0,02651357 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01569216 0,02649497 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01569216 0,02647639 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01569216 0,02645783 ! glycine metabolic process GO:0006544 28 17 0,000 0,01569216 0,02643931 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01569216 0,0264208 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01569216 0,02640233 ! NAD metabolic process GO:0019674 29 17 0,000 0,01569216 0,02638388 ! membrane budding GO:0006900 37 17 0,000 0,01569216 0,02636545 ! DNA integration GO:0015074 29 17 0,000 0,01569216 0,02634706 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01569216 0,02632868 ! regulation of protein binding GO:0043393 33 17 0,000 0,01569216 0,02631033 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01569216 0,02629201 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01569216 0,02627372 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01569216 0,02625545 ! genitalia development GO:0048806 30 17 0,000 0,01569216 0,0262372 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01569216 0,02621898 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01569216 0,02620078 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01569216 0,02618261 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01569216 0,02616447 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01569216 0,02614635 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01569216 0,02612826 ! steroid catabolic process GO:0006706 31 17 0,000 0,01569216 0,02611019 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01569216 0,02609214 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01569216 0,02607412 ! gas transport GO:0015669 25 17 0,000 0,01569216 0,02605613 ! organic cation transport GO:0015695 31 17 0,000 0,01569216 0,02603816 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01569216 0,02602021 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01569216 0,02600229 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01569216 0,0259844 ! microspike assembly GO:0030035 36 17 0,000 0,01569216 0,02596653 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01569216 0,02594868 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01569216 0,02593086 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01660779 0,02742508 ! neuron maturation GO:0042551 42 18 0,000 0,01660779 0,02740627 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01660779 0,02738749 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01660779 0,02736873 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01660779 0,02735 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01660779 0,02733129 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01660779 0,02731261 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01660779 0,02729395 ! memory GO:0007613 31 18 0,000 0,01660779 0,02727532 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01660779 0,02725672 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01660779 0,02723814 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01660779 0,02721958 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01660779 0,02720105 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01660779 0,02718255 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01660779 0,02716407 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01660779 0,02714562 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01660779 0,02712719 ! response to retinoic acid GO:0032526 26 18 0,000 0,01660779 0,02710878 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01660779 0,02709041 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01660779 0,02707205 ! response to fungus GO:0009620 21 18 0,000 0,01660779 0,02705372 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01660779 0,02703542 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01660779 0,02701714 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01660779 0,02699888 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01660779 0,02698065 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01660779 0,02696245 ! vitamin transport GO:0051180 27 18 0,000 0,01660779 0,02694427 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01660779 0,02692611 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01660779 0,02690798 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01660779 0,02688987 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01660779 0,02687179 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01660779 0,02685373 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01660779 0,02683569 ! nerve development GO:0021675 28 18 0,000 0,01660779 0,02681768 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01660779 0,0267997 ! protein secretion GO:0009306 39 19 0,000 0,01752261 0,02825696 ! positive regulation of translation GO:0045727 30 19 0,000 0,01752261 0,02823804 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01752261 0,02821914 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01752261 0,02820026 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01752261 0,02818141 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01752261 0,02816259 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01752261 0,02814379 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01752261 0,02812501 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01752261 0,02810626 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01752261 0,02808754 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01752261 0,02806884 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01752261 0,02805016 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01752261 0,02803151 ! cerebral cortex development GO:0021987 36 19 0,000 0,01752261 0,02801288 ! pigmentation during development GO:0048066 41 19 0,000 0,01752261 0,02799428 ! response to vitamin A GO:0033189 27 19 0,000 0,01752261 0,02797571 ! heme metabolic process GO:0042168 36 19 0,000 0,01752261 0,02795716 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01752261 0,02793863 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01752261 0,02792013 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01752261 0,02790165 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01752261 0,02788319 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01752261 0,02786477 ! peptide cross-linking GO:0018149 37 19 0,000 0,01752261 0,02784636 ! protein export from nucleus GO:0006611 36 19 0,000 0,01752261 0,02782798 ! heart process GO:0003015 30 19 0,000 0,01752261 0,02780962 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01752261 0,02779129 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01752261 0,02777298 ! visual learning GO:0008542 36 19 0,000 0,01752261 0,0277547 ! cellular pigmentation GO:0033059 36 19 0,000 0,01752261 0,02773644 ! G1 phase GO:0051318 40 19 0,000 0,01752261 0,02771821 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01752261 0,02769999 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01752261 0,02768181 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01752261 0,02766364 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01752261 0,0276455 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01752261 0,02762739 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01752261 0,02760929 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01752261 0,02759122 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01752261 0,02757318 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01752261 0,02755516 ! cilium assembly GO:0042384 37 19 0,000 0,01752261 0,02753716 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01752261 0,02751918 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0184366 0,02893572 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0184366 0,02891686 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0184366 0,02889802 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0184366 0,0288792 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0184366 0,02886042 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,0184366 0,02884165 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0184366 0,02882291 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0184366 0,02880419 ! response to vitamin GO:0033273 31 20 0,000 0,0184366 0,0287855 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0184366 0,02876683 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0184366 0,02874819 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0184366 0,02872957 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0184366 0,02871098 ! response to alkaloid GO:0043279 38 20 0,000 0,0184366 0,0286924 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0184366 0,02867386 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0184366 0,02865533 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0184366 0,02863684 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0184366 0,02861836 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0184366 0,02859991 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0184366 0,02858148 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0184366 0,02856308 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0184366 0,0285447 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0184366 0,02852634 ! body fluid secretion GO:0007589 31 20 0,000 0,0184366 0,02850801 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0184366 0,0284897 ! peptide secretion GO:0002790 35 20 0,000 0,0184366 0,02847141 ! stem cell differentiation GO:0048863 53 20 0,000 0,0184366 0,02845315 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0184366 0,02843491 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0184366 0,02841669 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0184366 0,0283985 ! sensory perception of pain GO:0019233 30 20 0,000 0,0184366 0,02838033 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0184366 0,02836219 ! diencephalon development GO:0021536 34 20 0,000 0,0184366 0,02834406 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0184366 0,02832596 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0184366 0,02830789 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0184366 0,02828983 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0184366 0,0282718 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0184366 0,02825379 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0184366 0,02823581 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0184366 0,02821785 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0184366 0,02819991 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0184366 0,02818199 ! regulation of glucose import GO:0046324 29 20 0,000 0,0184366 0,0281641 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0184366 0,02814623 ! actin filament-based movement GO:0030048 43 20 0,000 0,0184366 0,02812838 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0184366 0,02811056 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0184366 0,02809275 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0184366 0,02807497 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0184366 0,02805722 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0184366 0,02803948 ! regulation of cell killing GO:0031341 42 21 0,000 0,01934977 0,0294097 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01934977 0,02939113 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01934977 0,02937259 ! hormone secretion GO:0046879 38 21 0,000 0,01934977 0,02935407 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01934977 0,02933557 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01934977 0,0293171 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01934977 0,02929865 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01934977 0,02928022 ! axis specification GO:0009798 38 21 0,000 0,01934977 0,02926182 ! ovarian follicle development GO:0001541 35 21 0,000 0,01934977 0,02924344 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01934977 0,02922508 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01934977 0,02920675 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01934977 0,02918843 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01934977 0,02917015 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01934977 0,02915188 ! cell aging GO:0007569 44 21 0,000 0,01934977 0,02913364 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01934977 0,02911542 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01934977 0,02909722 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01934977 0,02907905 ! cytolysis GO:0019835 24 21 0,000 0,01934977 0,02906089 ! vasodilation GO:0042311 39 21 0,000 0,01934977 0,02904277 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01934977 0,02902466 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01934977 0,02900657 ! DNA modification GO:0006304 34 21 0,000 0,01934977 0,02898851 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01934977 0,02897047 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01934977 0,02895246 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01934977 0,02893446 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01934977 0,02891649 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01934977 0,02889854 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01934977 0,02888062 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01934977 0,02886271 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01934977 0,02884483 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01934977 0,02882697 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01934977 0,02880913 ! collagen catabolic process GO:0030574 28 21 0,000 0,01934977 0,02879131 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01934977 0,02877352 ! gut development GO:0048565 39 21 0,000 0,01934977 0,02875575 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02026213 0,03009301 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02026213 0,03007445 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02026213 0,0300559 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02026213 0,03003739 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02026213 0,03001889 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02026213 0,03000042 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02026213 0,02998197 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02026213 0,02996354 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02026213 0,02994513 ! regeneration GO:0031099 41 22 0,000 0,02026213 0,02992675 ! keratinization GO:0031424 28 22 0,000 0,02026213 0,02990839 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02026213 0,02989005 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02026213 0,02987174 ! sensory perception of taste GO:0050909 28 22 0,000 0,02026213 0,02985345 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02026213 0,02983518 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02026213 0,02981693 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02026213 0,0297987 ! vacuolar transport GO:0007034 36 22 0,000 0,02026213 0,0297805 ! lysosome organization GO:0007040 41 22 0,000 0,02026213 0,02976232 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02026213 0,02974416 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02026213 0,02972602 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02026213 0,02970791 ! fucose metabolic process GO:0006004 39 22 0,000 0,02026213 0,02968982 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02026213 0,02967174 ! ureteric bud development GO:0001657 43 22 0,000 0,02026213 0,0296537 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02026213 0,02963567 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02026213 0,02961767 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02026213 0,02959968 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02026213 0,02958172 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02026213 0,02956378 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02026213 0,02954586 ! sarcomere organization GO:0045214 30 22 0,000 0,02026213 0,02952797 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02026213 0,02951009 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02026213 0,02949224 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02026213 0,02947441 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02026213 0,0294566 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02026213 0,02943881 ! protein stabilization GO:0050821 39 22 0,000 0,02026213 0,02942105 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02117366 0,03072607 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02117366 0,03070755 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02117366 0,03068905 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02117366 0,03067058 ! gluconeogenesis GO:0006094 33 23 0,000 0,02117366 0,03065212 ! viral genome replication GO:0019079 41 23 0,000 0,02117366 0,03063369 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02117366 0,03061528 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02117366 0,0305969 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02117366 0,03057853 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02117366 0,03056019 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02117366 0,03054187 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02117366 0,03052357 ! visual behavior GO:0007632 42 23 0,000 0,02117366 0,03050529 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02117366 0,03048703 ! response to ethanol GO:0045471 46 23 0,000 0,02117366 0,0304688 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02117366 0,03045059 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02117366 0,0304324 ! peroxisome organization GO:0007031 37 23 0,000 0,02117366 0,03041423 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02117366 0,03039608 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02117366 0,03037796 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02117366 0,03035985 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02117366 0,03034177 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02117366 0,03032371 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02117366 0,03030567 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02117366 0,03028765 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02117366 0,03026966 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02117366 0,03025168 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02117366 0,03023373 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02117366 0,0302158 ! fatty acid transport GO:0015908 44 23 0,000 0,02117366 0,03019788 ! platelet activation GO:0030168 37 23 0,000 0,02117366 0,03017999 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02117366 0,03016213 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02117366 0,03014428 ! hormone transport GO:0009914 40 23 0,000 0,02117366 0,03012645 ! cell-cell recognition GO:0009988 25 23 0,000 0,02117366 0,03010865 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02117366 0,03009086 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02117366 0,0300731 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02117366 0,03005536 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02117366 0,03003764 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02117366 0,03001994 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02208438 0,03129271 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02208438 0,03127429 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02208438 0,03125589 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02208438 0,03123752 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02208438 0,03121916 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02208438 0,03120083 ! vesicle docking GO:0048278 47 24 0,000 0,02208438 0,03118252 ! spinal cord development GO:0021510 47 24 0,000 0,02208438 0,03116423 ! vacuole organization GO:0007033 43 24 0,000 0,02208438 0,03114597 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02208438 0,03112772 ! digestive system process GO:0022600 39 24 0,000 0,02208438 0,0311095 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02208438 0,03109129 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02208438 0,03107311 ! regulation of behavior GO:0050795 43 24 0,000 0,02208438 0,03105495 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02208438 0,03103681 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02208438 0,03101869 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02208438 0,03100059 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02208438 0,03098252 ! membrane depolarization GO:0051899 39 24 0,000 0,02208438 0,03096446 ! pallium development GO:0021543 49 24 0,000 0,02208438 0,03094643 ! pentose metabolic process GO:0019321 35 24 0,000 0,02208438 0,03092842 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02208438 0,03091042 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02208438 0,03089245 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02208438 0,0308745 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02208438 0,03085657 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02208438 0,03083866 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02208438 0,03082078 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02208438 0,03080291 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02208438 0,03078506 ! regulation of amine transport GO:0051952 40 24 0,000 0,02208438 0,03076724 ! protein tetramerization GO:0051262 52 24 0,000 0,02208438 0,03074943 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02299428 0,03199782 ! myelination GO:0042552 45 25 0,000 0,02299428 0,03197933 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02299428 0,03196085 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02299428 0,0319424 ! phototransduction GO:0007602 33 25 0,000 0,02299428 0,03192397 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02299428 0,03190556 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02299428 0,03188717 ! sperm motility GO:0030317 31 25 0,000 0,02299428 0,0318688 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02299428 0,03185045 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02299428 0,03183213 ! receptor metabolic process GO:0043112 46 25 0,000 0,02299428 0,03181382 ! response to starvation GO:0042594 42 25 0,000 0,02299428 0,03179554 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02299428 0,03177728 ! neural crest cell development GO:0014032 54 25 0,000 0,02299428 0,03175903 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02299428 0,03174081 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02299428 0,03172261 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02299428 0,03170443 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02299428 0,03168628 ! interaction with host GO:0051701 62 25 0,000 0,02299428 0,03166814 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02299428 0,03165002 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02299428 0,03163193 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02299428 0,03161385 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02299428 0,0315958 ! immunoglobulin production GO:0002377 55 25 0,000 0,02299428 0,03157776 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02299428 0,03155975 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02299428 0,03154176 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02299428 0,03152378 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02299428 0,03150583 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02299428 0,0314879 ! telomere organization GO:0032200 43 25 0,000 0,02299428 0,03146999 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02299428 0,0314521 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02299428 0,03143423 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02390336 0,03265843 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02390336 0,03263989 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02390336 0,03262138 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02390336 0,03260289 ! initiation of viral infection GO:0019059 57 26 0,000 0,02390336 0,03258442 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02390336 0,03256597 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02390336 0,03254754 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02390336 0,03252913 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02390336 0,03251074 ! molting cycle process GO:0022404 50 26 0,000 0,02390336 0,03249237 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02390336 0,03247402 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02390336 0,0324557 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02390336 0,03243739 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02390336 0,03241911 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02390336 0,03240084 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02390336 0,0323826 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02390336 0,03236438 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02390336 0,03234617 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02390336 0,03232799 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02390336 0,03230983 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02390336 0,03229169 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02390336 0,03227357 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02390336 0,03225547 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02390336 0,03223739 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02390336 0,03221932 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02390336 0,03220128 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02390336 0,03218327 ! blastocyst development GO:0001824 49 26 0,000 0,02390336 0,03216527 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02390336 0,03214729 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02390336 0,03212933 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02390336 0,03211139 ! neuron fate commitment GO:0048663 48 27 0,000 0,02481163 0,03331294 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02481163 0,03329436 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02481163 0,0332758 ! iron ion transport GO:0006826 59 27 0,000 0,02481163 0,03325726 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02481163 0,03323875 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02481163 0,03322025 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02481163 0,03320177 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02481163 0,03318332 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02481163 0,03316488 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02481163 0,03314647 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02481163 0,03312807 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02481163 0,0331097 ! autophagy GO:0006914 41 27 0,000 0,02481163 0,03309135 ! male gonad development GO:0008584 44 27 0,000 0,02481163 0,03307301 ! response to toxin GO:0009636 47 27 0,000 0,02481163 0,0330547 ! primary neural tube formation GO:0014020 51 27 0,000 0,02481163 0,03303641 ! base-excision repair GO:0006284 41 27 0,000 0,02481163 0,03301814 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02481163 0,03299988 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02481163 0,03298165 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02481163 0,03296344 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02481163 0,03294525 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02481163 0,03292708 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02481163 0,03290892 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02481163 0,03289079 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02481163 0,03287268 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02571909 0,0340562 ! circadian rhythm GO:0007623 50 28 0,000 0,02571909 0,03403747 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02571909 0,03401876 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02571909 0,03400007 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02571909 0,0339814 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02571909 0,03396275 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02571909 0,03394412 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02571909 0,03392551 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02571909 0,03390692 ! synaptogenesis GO:0007416 42 28 0,000 0,02571909 0,03388835 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02571909 0,0338698 ! lipid oxidation GO:0034440 43 28 0,000 0,02571909 0,03385127 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02571909 0,03383276 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02571909 0,03381427 ! translational initiation GO:0006413 65 29 0,000 0,02662573 0,03498716 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02662573 0,03496807 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02662573 0,03494899 ! regulation of pH GO:0006885 43 29 0,000 0,02662573 0,03492993 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02662573 0,0349109 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02662573 0,03489188 ! catechol metabolic process GO:0009712 54 29 0,000 0,02662573 0,03487289 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02662573 0,03485391 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02662573 0,03483496 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02662573 0,03481603 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02662573 0,03479712 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02662573 0,03477823 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02662573 0,03475936 ! cell fate determination GO:0001709 60 29 0,000 0,02662573 0,03474051 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02662573 0,03472168 ! detection of light stimulus GO:0009583 38 29 0,000 0,02662573 0,03470287 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02662573 0,03468408 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02662573 0,03466531 ! tissue homeostasis GO:0001894 48 29 0,000 0,02662573 0,03464656 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02662573 0,03462784 ! phenol metabolic process GO:0018958 55 30 0,000 0,02753155 0,03578655 ! zinc ion transport GO:0006829 45 30 0,000 0,02753155 0,03576723 ! membrane docking GO:0022406 61 30 0,000 0,02753155 0,03574793 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02753155 0,03572865 ! cell junction assembly GO:0034329 78 30 0,000 0,02753155 0,03570939 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02753155 0,03569015 ! acute-phase response GO:0006953 49 30 0,000 0,02753155 0,03567093 ! myofibril assembly GO:0030239 47 30 0,000 0,02753155 0,03565173 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02753155 0,03563255 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02753155 0,03561339 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02753155 0,03559426 ! phospholipid transport GO:0015914 51 30 0,000 0,02753155 0,03557514 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02753155 0,03555605 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02753155 0,03553697 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02753155 0,03551792 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02753155 0,03549888 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02753155 0,03547987 ! eye morphogenesis GO:0048592 60 30 0,000 0,02753155 0,03546087 ! response to heat GO:0009408 50 30 0,000 0,02753155 0,0354419 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02843656 0,03658736 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02843656 0,03656781 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02843656 0,03654828 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02843656 0,03652876 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02843656 0,03650927 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02843656 0,0364898 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02843656 0,03647035 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02843656 0,03645092 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02843656 0,03643151 ! ovulation cycle process GO:0022602 49 31 0,000 0,02843656 0,03641212 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02843656 0,03639275 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02843656 0,0363734 ! peptide transport GO:0015833 55 31 0,000 0,02843656 0,03635408 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02843656 0,03633477 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02843656 0,03631548 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02843656 0,03629622 ! mesoderm formation GO:0001707 69 31 0,000 0,02843656 0,03627697 ! natural killer cell activation GO:0030101 45 31 0,000 0,02843656 0,03625775 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02843656 0,03623854 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02843656 0,03621936 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02843656 0,0362002 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02843656 0,03618105 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02843656 0,03616193 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02934076 0,03729206 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02934076 0,03727238 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02934076 0,03725271 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02934076 0,03723306 ! cholesterol transport GO:0030301 56 32 0,000 0,02934076 0,03721343 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02934076 0,03719382 ! spliceosome assembly GO:0000245 67 32 0,000 0,02934076 0,03717424 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02934076 0,03715467 ! metanephros development GO:0001656 74 32 0,000 0,02934076 0,03713513 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02934076 0,0371156 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02934076 0,0370961 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02934076 0,03707662 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02934076 0,03705715 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02934076 0,03703771 ! muscle cell development GO:0055001 49 32 0,000 0,02934076 0,03701829 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02934076 0,03699889 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02934076 0,03697951 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02934076 0,03696015 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02934076 0,03694081 ! ovulation cycle GO:0042698 51 32 0,000 0,02934076 0,03692148 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02934076 0,03690218 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02934076 0,0368829 ! hindbrain development GO:0030902 61 32 0,000 0,02934076 0,03686364 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02934076 0,0368444 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02934076 0,03682518 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02934076 0,03680598 ! gene silencing GO:0016458 65 32 0,000 0,02934076 0,03678681 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03024415 0,0378997 ! post-embryonic development GO:0009791 69 33 0,000 0,03024415 0,03787998 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03024415 0,03786027 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03024415 0,03784058 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03024415 0,03782091 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03024415 0,03780126 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03024415 0,03778164 ! cell fate specification GO:0001708 52 33 0,000 0,03024415 0,03776203 ! sterol transport GO:0015918 57 33 0,000 0,03024415 0,03774244 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03024415 0,03772288 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03024415 0,03770333 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03024415 0,03768381 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03024415 0,0376643 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03024415 0,03764482 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03114673 0,03874821 ! glial cell differentiation GO:0010001 63 34 0,000 0,03114673 0,03872818 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03114673 0,03870818 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03114673 0,0386882 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03114673 0,03866823 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03114673 0,03864829 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03114673 0,03862837 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03114673 0,03860847 ! mismatch repair GO:0006298 46 34 0,000 0,03114673 0,03858859 ! spermatid development GO:0007286 63 34 0,000 0,03114673 0,03856873 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03114673 0,03854889 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03114673 0,03852907 ! placenta development GO:0001890 53 34 0,000 0,03114673 0,03850927 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03114673 0,03848949 ! regulation of muscle development GO:0048634 70 35 0,000 0,0320485 0,03958352 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0320485 0,03956321 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0320485 0,03954292 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0320485 0,03952265 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0320485 0,0395024 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0320485 0,03948218 ! odontogenesis GO:0042476 66 35 0,000 0,0320485 0,03946197 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0320485 0,03944179 ! female gonad development GO:0008585 58 35 0,000 0,0320485 0,03942162 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0320485 0,03940148 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0320485 0,03938135 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0320485 0,03936125 ! cytokine production GO:0001816 59 35 0,000 0,0320485 0,03934117 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0320485 0,03932111 ! neural tube formation GO:0001841 67 35 0,000 0,0320485 0,03930107 ! vesicle localization GO:0051648 64 35 0,000 0,0320485 0,03928104 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03294946 0,04036476 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03294946 0,04034422 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03294946 0,0403237 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03294946 0,0403032 ! cell junction organization GO:0034330 86 36 0,000 0,03294946 0,04028272 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03294946 0,04026226 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03294946 0,04024183 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03294946 0,04022141 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03294946 0,04020101 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03294946 0,04018064 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03294946 0,04016028 ! aerobic respiration GO:0009060 55 36 0,000 0,03294946 0,04013995 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03294946 0,04011963 ! embryonic organ development GO:0048568 57 36 0,000 0,03294946 0,04009934 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03294946 0,04007907 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03294946 0,04005882 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03384961 0,0411324 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03384961 0,04111164 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03384961 0,0410909 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03384961 0,04107018 ! organic anion transport GO:0015711 68 37 0,000 0,03384961 0,04104947 ! tissue remodeling GO:0048771 76 37 0,000 0,03384961 0,0410288 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03384961 0,04100814 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03384961 0,0409875 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03384961 0,04096688 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03384961 0,04094628 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03384961 0,04092571 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03384961 0,04090515 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03384961 0,04088462 ! pigment metabolic process GO:0042440 80 37 0,000 0,03384961 0,0408641 ! spermatid differentiation GO:0048515 66 37 0,000 0,03384961 0,04084361 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03384961 0,04082314 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03474895 0,04188676 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03474895 0,04186579 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03474895 0,04184483 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03474895 0,0418239 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03474895 0,04180299 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03474895 0,0417821 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03474895 0,04176123 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03474895 0,04174038 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,03474895 0,04171955 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03474895 0,04169874 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03474895 0,04167795 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03474895 0,04165719 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03474895 0,04163644 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03474895 0,04161572 ! glucan metabolic process GO:0044042 62 38 0,000 0,03474895 0,04159501 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03564749 0,04264935 ! mammary gland development GO:0030879 86 39 0,000 0,03564749 0,04262816 ! learning GO:0007612 77 39 0,000 0,03564749 0,04260698 ! ear morphogenesis GO:0042471 60 39 0,000 0,03564749 0,04258582 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03564749 0,04256469 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03564749 0,04254358 ! segmentation GO:0035282 67 39 0,000 0,03564749 0,04252248 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03564749 0,04250141 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03564749 0,04248036 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03564749 0,04245933 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03564749 0,04243832 ! RNA modification GO:0009451 57 39 0,000 0,03564749 0,04241733 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03564749 0,04239637 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03654521 0,04344258 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03654521 0,04342113 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03654521 0,0433997 ! feeding behavior GO:0007631 59 40 0,000 0,03654521 0,04337829 ! negative regulation of binding GO:0051100 72 40 0,000 0,03654521 0,0433569 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03654521 0,04333553 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03654521 0,04331418 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03654521 0,04329285 ! maintenance of protein location GO:0045185 91 40 0,000 0,03654521 0,04327155 ! cytokinesis GO:0000910 72 40 0,000 0,03654521 0,04325026 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03744214 0,04428996 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03744214 0,0442682 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03744214 0,04424645 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03744214 0,04422473 ! gliogenesis GO:0042063 88 41 0,000 0,03744214 0,04420303 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03744214 0,04418135 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03744214 0,0441597 ! T cell differentiation GO:0030217 81 41 0,000 0,03744214 0,04413806 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03744214 0,04411644 ! polyol metabolic process GO:0019751 66 41 0,000 0,03744214 0,04409485 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03744214 0,04407328 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03833825 0,04510603 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03833825 0,04508399 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03833825 0,04506196 ! regulation of tube size GO:0035150 71 42 0,000 0,03833825 0,04503996 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03833825 0,04501798 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03833825 0,04499602 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03833825 0,04497408 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03833825 0,04495216 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03833825 0,04493027 ! neuron migration GO:0001764 79 42 0,000 0,03833825 0,04490839 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03833825 0,04488654 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03833825 0,04486471 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03923357 0,04589011 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03923357 0,04586781 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03923357 0,04584554 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03923357 0,04582328 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03923357 0,04580105 ! glucose transport GO:0015758 65 43 0,000 0,03923357 0,04577884 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03923357 0,04575665 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03923357 0,04573448 ! neural tube development GO:0021915 77 43 0,000 0,03923357 0,04571233 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03923357 0,0456902 ! striated muscle contraction GO:0006941 77 43 0,000 0,03923357 0,0456681 ! phagocytosis GO:0006909 90 43 0,000 0,03923357 0,04564602 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03923357 0,04562395 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04012807 0,04664162 ! hexose transport GO:0008645 67 44 0,000 0,04012807 0,0466191 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04012807 0,0465966 ! male sex differentiation GO:0046661 76 44 0,000 0,04012807 0,04657412 ! double-strand break repair GO:0006302 81 44 0,000 0,04012807 0,04655166 ! biopolymer methylation GO:0043414 84 44 0,000 0,04012807 0,04652923 ! B cell differentiation GO:0030183 107 44 0,000 0,04012807 0,04650682 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04012807 0,04648442 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04012807 0,04646205 ! developmental growth GO:0048589 82 44 0,000 0,04012807 0,04643971 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04012807 0,04641738 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,04102178 0,04742835 ! glycolysis GO:0006096 65 45 0,000 0,04102178 0,04740557 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,04102178 0,04738282 ! leukocyte migration GO:0050900 68 45 0,000 0,04102178 0,04736008 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,04102178 0,04733736 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,04102178 0,04731467 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,04102178 0,047292 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,04102178 0,04726935 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,04102178 0,04724672 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,04102178 0,04722412 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,04102178 0,04720153 ! cell growth GO:0016049 84 45 0,000 0,04102178 0,04717897 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,04191468 0,04818286 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,04191468 0,04815985 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,04191468 0,04813686 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,04191468 0,0481139 ! pigmentation GO:0043473 100 46 0,000 0,04191468 0,04809095 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,04191468 0,04806803 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04280679 0,04906771 ! endosome transport GO:0016197 108 47 0,000 0,04280679 0,04904435 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04280679 0,049021 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04280679 0,04899768 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04280679 0,04897438 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04280679 0,04895111 ! JNK cascade GO:0007254 91 47 0,000 0,04280679 0,04892785 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,04280679 0,04890462 ! methylation GO:0032259 90 47 0,000 0,04280679 0,04888141 ! protein homooligomerization GO:0051260 76 47 0,000 0,04280679 0,04885822 ! mitochondrial transport GO:0006839 82 48 0,000 0,04369809 0,04985187 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04369809 0,04982824 ! cellular component disassembly GO:0022411 86 48 0,000 0,04369809 0,04980464 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04369809 0,04978106 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04369809 0,0497575 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04369809 0,04973396 ! activation of caspase activity GO:0006919 84 48 0,000 0,04369809 0,04971045 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04369809 0,04968695 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04369809 0,04966348 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04369809 0,04964004 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04458859 0,05062772 ! regulation of action potential GO:0001508 95 49 0,000 0,04458859 0,05060384 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04458859 0,05057998 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04458859 0,05055614 ! regulation of ion transport GO:0043269 77 49 0,000 0,04458859 0,05053233 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04458859 0,05050854 ! peptide metabolic process GO:0006518 76 49 0,000 0,04458859 0,05048477 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04458859 0,05046103 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04458859 0,0504373 ! endocrine system development GO:0035270 104 49 0,000 0,04458859 0,0504136 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04458859 0,05038992 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04458859 0,05036626 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04458859 0,05034263 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04458859 0,05031901 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04547829 0,051299 ! neuromuscular process GO:0050905 99 50 0,000 0,04547829 0,05127496 ! regulation of ossification GO:0030278 117 50 0,000 0,04547829 0,05125094 ! inner ear development GO:0048839 79 50 0,000 0,04547829 0,05122695 ! histone modification GO:0016570 91 50 0,000 0,04547829 0,05120298 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04547829 0,05117903 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04547829 0,0511551 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04547829 0,0511312 ! positive regulation of binding GO:0051099 78 51 0,000 0,04636719 0,05210624 ! viral infectious cycle GO:0019058 99 51 0,000 0,04636719 0,05208191 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04636719 0,05205761 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04636719 0,05203333 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04636719 0,05200907 ! excretion GO:0007588 83 51 0,000 0,04636719 0,05198484 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04636719 0,05196062 ! chromatin remodeling GO:0006338 109 51 0,000 0,04636719 0,05193643 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04636719 0,05191226 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04636719 0,05188812 ! vesicle organization GO:0016050 107 51 0,000 0,04636719 0,051864 ! regulation of cell shape GO:0008360 125 51 0,000 0,04636719 0,0518399 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04636719 0,05181582 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04725529 0,05278377 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04725529 0,05275927 ! membrane fusion GO:0006944 110 52 0,000 0,04725529 0,0527348 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04725529 0,05271035 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04725529 0,05268593 ! amino acid activation GO:0043038 92 52 0,000 0,04725529 0,05266153 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04725529 0,05263715 ! synapse organization GO:0050808 85 52 0,000 0,04725529 0,05261279 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0481426 0,0535759 ! RNA catabolic process GO:0006401 93 53 0,000 0,0481426 0,05355113 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0481426 0,05352638 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0481426 0,05350166 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0481426 0,05347696 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0481426 0,05345228 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0481426 0,05342763 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0481426 0,05340299 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04902911 0,05436131 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04902911 0,05433627 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04902911 0,05431125 ! cell recognition GO:0008037 85 54 0,000 0,04902911 0,05428626 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04902911 0,05426128 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04902911 0,05423634 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04902911 0,05421141 ! chloride transport GO:0006821 90 55 0,000 0,04991482 0,05516539 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04991482 0,05514006 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04991482 0,05511476 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04991482 0,05508948 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04991482 0,05506422 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04991482 0,05503898 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04991482 0,05501377 ! aging GO:0007568 103 55 0,000 0,04991482 0,05498858 ! gastrulation GO:0007369 112 55 0,000 0,04991482 0,05496341 ! heart morphogenesis GO:0003007 97 55 0,000 0,04991482 0,05493827 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04991482 0,05491315 ! RNA elongation GO:0006354 79 55 0,000 0,04991482 0,05488805 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04991482 0,05486298 ! regulation of actin filament length GO:0030832 105 56 0,000 0,05079974 0,05581012 ! sensory perception of smell GO:0007608 80 56 0,000 0,05079974 0,05578465 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,05079974 0,0557592 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,05079974 0,05573377 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,05079974 0,05570837 ! regulation of DNA replication GO:0006275 101 56 0,000 0,05079974 0,05568299 ! proton transport GO:0015992 94 56 0,000 0,05079974 0,05565764 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,05079974 0,0556323 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,05168386 0,05657478 ! muscle fiber development GO:0048747 112 57 0,000 0,05168386 0,05654905 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,05168386 0,05652335 ! lipid modification GO:0030258 97 57 0,000 0,05168386 0,05649767 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,05168386 0,05647201 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,05168386 0,05644638 ! maintenance of location GO:0051235 118 57 0,000 0,05168386 0,05642077 ! hydrogen transport GO:0006818 97 58 0,000 0,05256719 0,05735903 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05256719 0,05733303 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05256719 0,05730705 ! adult behavior GO:0030534 99 58 0,000 0,05256719 0,05728109 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05256719 0,05725516 ! positive regulation of secretion GO:0051047 95 59 0,000 0,05344972 0,05819006 ! regulation of cellular component size GO:0032535 109 59 0,000 0,05344972 0,05816374 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,05344972 0,05813745 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,05344972 0,05811118 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,05344972 0,05808493 ! DNA catabolic process GO:0006308 86 59 0,000 0,05344972 0,05805871 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,05344972 0,05803251 ! establishment of organelle localization GO:0051656 109 59 0,000 0,05344972 0,05800633 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05433147 0,05893666 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05433147 0,0589101 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05433147 0,05888356 ! camera-type eye development GO:0043010 116 60 0,000 0,05433147 0,05885705 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05433147 0,05883056 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05433147 0,0588041 ! kidney development GO:0001822 122 60 0,000 0,05433147 0,05877766 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,05521242 0,05970385 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,05521242 0,05967703 ! mesoderm development GO:0007498 119 61 0,000 0,05521242 0,05965023 ! tRNA processing GO:0008033 89 61 0,000 0,05521242 0,05962346 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,05521242 0,05959671 ! ear development GO:0043583 103 62 0,000 0,05609257 0,06051961 ! viral reproductive process GO:0022415 126 62 0,000 0,05609257 0,06049249 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05609257 0,06046538 ! gonad development GO:0008406 98 62 0,000 0,05609257 0,0604383 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05609257 0,06041125 ! regulation of mitosis GO:0007088 105 63 0,000 0,05697194 0,06133087 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05697194 0,06130344 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,05697194 0,06127604 ! detection of external stimulus GO:0009581 91 63 0,000 0,05697194 0,06124866 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05697194 0,0612213 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05697194 0,06119397 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05785052 0,06210993 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05785052 0,06208223 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05785052 0,06205455 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05785052 0,0620269 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05785052 0,06199927 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05785052 0,06197166 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05872831 0,06288398 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05872831 0,06285601 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05872831 0,06282806 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05872831 0,06280014 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05960531 0,06370963 ! actin filament organization GO:0007015 148 66 0,000 0,05960531 0,06368134 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05960531 0,06365307 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05960531 0,06362483 ! secondary metabolic process GO:0019748 116 66 0,000 0,05960531 0,06359662 ! cell projection assembly GO:0030031 120 66 0,000 0,05960531 0,06356843 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,06048152 0,06447432 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,06048152 0,06444577 ! activation of MAPK activity GO:0000187 115 67 0,000 0,06048152 0,06441724 ! lung development GO:0030324 144 67 0,000 0,06048152 0,06438874 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,06048152 0,06436026 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,06048152 0,0643318 ! hexose catabolic process GO:0019320 104 67 0,000 0,06048152 0,06430338 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,06048152 0,06427497 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,06048152 0,0642466 ! adaptive immune response GO:0002250 119 67 0,000 0,06048152 0,06421824 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,06048152 0,06418992 ! amino acid transport GO:0006865 125 68 0,000 0,06135695 0,06509031 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,06135695 0,06506162 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,06135695 0,06503296 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,06135695 0,06500432 ! viral reproduction GO:0016032 134 68 0,000 0,06135695 0,06497571 ! regulation of lipase activity GO:0060191 130 68 0,000 0,06135695 0,06494712 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,06135695 0,06491856 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,06223158 0,06581503 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06223158 0,06578611 ! urogenital system development GO:0001655 137 69 0,000 0,06223158 0,06575722 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06223158 0,06572836 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06223158 0,06569951 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06223158 0,0656707 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06310544 0,06656365 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,06310544 0,06653448 ! amine catabolic process GO:0009310 117 71 0,000 0,0639785 0,06742544 ! reproductive structure development GO:0048608 113 71 0,000 0,0639785 0,06739592 ! appendage development GO:0048736 136 71 0,000 0,0639785 0,06736643 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0639785 0,06733696 ! B cell activation GO:0042113 160 71 0,000 0,0639785 0,06730751 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0639785 0,0672781 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0639785 0,0672487 ! acute inflammatory response GO:0002526 113 72 0,000 0,06485079 0,06813581 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06485079 0,06810606 ! carbohydrate transport GO:0008643 110 72 0,000 0,06485079 0,06807635 ! respiratory system development GO:0060541 153 72 0,000 0,06485079 0,06804666 ! learning or memory GO:0007611 147 73 0,000 0,06572229 0,06893105 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06572229 0,06890101 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06572229 0,068871 ! axon guidance GO:0007411 139 73 0,000 0,06572229 0,06884102 ! fertilization GO:0009566 90 73 0,000 0,06572229 0,06881106 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,066593 0,06969237 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,066593 0,06966207 ! neurotransmitter transport GO:0006836 123 74 0,000 0,066593 0,0696318 ! exocytosis GO:0006887 133 74 0,000 0,066593 0,06960155 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,066593 0,06957132 ! eye development GO:0001654 143 74 0,000 0,066593 0,06954113 ! organelle localization GO:0051640 136 74 0,000 0,066593 0,06951096 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06746293 0,07038847 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06746293 0,07035796 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06746293 0,07032748 ! rhythmic process GO:0048511 128 75 0,000 0,06746293 0,07029702 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06746293 0,07026659 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06833209 0,07114106 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06833209 0,07111029 ! defense response to bacterium GO:0042742 89 76 0,000 0,06833209 0,07107955 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06833209 0,07104883 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,06833209 0,07101814 ! regulation of catabolic process GO:0009894 161 76 0,000 0,06833209 0,07098748 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06920046 0,07185857 ! blood coagulation GO:0007596 146 78 0,000 0,07006804 0,07272809 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,07006804 0,07269673 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,07006804 0,07266539 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,07006804 0,07263409 ! protein oligomerization GO:0051259 139 78 0,000 0,07006804 0,07260281 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,07093485 0,07346933 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,07093485 0,07343772 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,07093485 0,07340613 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,07093485 0,07337457 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,07180088 0,07423847 ! muscle cell differentiation GO:0042692 159 80 0,000 0,07180088 0,07420658 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,07180088 0,07417472 ! protein import into nucleus GO:0006606 158 80 0,000 0,07180088 0,07414289 ! inorganic anion transport GO:0015698 138 80 0,000 0,07180088 0,07411108 ! T cell activation GO:0042110 168 81 0,000 0,07266614 0,07497201 ! response to hypoxia GO:0001666 171 81 0,000 0,07266614 0,07493987 ! digestion GO:0007586 112 81 0,000 0,07266614 0,07490777 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,07266614 0,07487569 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,07266614 0,07484363 ! nuclear import GO:0051170 161 81 0,000 0,07266614 0,07481161 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,07266614 0,07477961 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,07353061 0,07563687 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,07353061 0,07560455 ! response to drug GO:0042493 143 82 0,000 0,07353061 0,07557226 ! response to nutrient GO:0007584 125 82 0,000 0,07353061 0,07553999 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,07353061 0,07550775 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,07353061 0,07547553 ! response to oxygen levels GO:0070482 176 83 0,000 0,07439431 0,07632951 ! regulation of lyase activity GO:0051339 160 83 0,000 0,07439431 0,07629698 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07525723 0,07714908 ! hemostasis GO:0007599 158 84 0,000 0,07525723 0,07711622 ! negative regulation of transport GO:0051051 153 84 0,000 0,07525723 0,07708339 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07525723 0,07705059 ! nucleosome assembly GO:0006334 122 85 0,000 0,07611937 0,07790013 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,07611937 0,07786701 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07698074 0,07871469 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07698074 0,07868125 ! chromatin assembly GO:0031497 124 86 0,000 0,07698074 0,07864784 ! tube morphogenesis GO:0035239 176 86 0,000 0,07698074 0,07861446 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07698074 0,07858111 ! amine transport GO:0015837 155 86 0,000 0,07698074 0,07854778 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07784134 0,07939223 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07784134 0,07935859 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07784134 0,07932497 ! regulation of protein transport GO:0051223 154 87 0,000 0,07784134 0,07929139 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 0,000 0,07870116 0,0801333 ! gland development GO:0048732 206 88 0,000 0,07870116 0,0800994 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07870116 0,08006554 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07870116 0,0800317 ! cellular defense response GO:0006968 114 89 0,000 0,07956021 0,08087109 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07956021 0,08083694 ! ossification GO:0001503 188 90 0,000 0,08041849 0,08167449 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,08041849 0,08164003 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,08041849 0,0816056 ! sex differentiation GO:0007548 145 90 0,000 0,08041849 0,0815712 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,08041849 0,08153682 ! bone development GO:0060348 189 91 0,000 0,08127599 0,08237154 ! sterol metabolic process GO:0016125 152 91 0,000 0,08127599 0,08233685 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,08127599 0,0823022 ! regulation of defense response GO:0031347 149 92 0,000 0,08213272 0,08313476 ! nucleosome organization GO:0034728 138 92 0,000 0,08213272 0,0830998 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,08213272 0,08306487 ! vitamin metabolic process GO:0006766 139 92 0,000 0,08213272 0,08302997 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,08298869 0,08386005 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,08298869 0,08382484 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,08298869 0,08378967 ! regulation of membrane potential GO:0042391 164 93 0,000 0,08298869 0,08375452 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,08298869 0,0837194 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,08384388 0,08454668 ! female pregnancy GO:0007565 164 94 0,000 0,08384388 0,08451126 ! transcription initiation GO:0006352 153 94 0,000 0,08384388 0,08447587 ! regulation of T cell activation GO:0050863 158 94 0,000 0,08384388 0,08444051 ! forebrain development GO:0030900 188 95 0,000 0,0846983 0,08526532 ! leukocyte differentiation GO:0002521 202 96 0,000 0,08555196 0,08608867 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,08555196 0,08605268 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,08555196 0,08601672 ! positive regulation of immune response GO:0050778 156 96 0,000 0,08555196 0,08598079 ! detection of stimulus GO:0051606 151 96 0,000 0,08555196 0,08594489 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,08640485 0,08676547 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08640485 0,08672927 ! protein ubiquitination GO:0016567 217 97 0,000 0,08640485 0,0866931 ! hormone metabolic process GO:0042445 157 97 0,000 0,08640485 0,08665697 ! regulation of protein localization GO:0032880 176 97 0,000 0,08640485 0,08662086 ! response to virus GO:0009615 160 98 0,000 0,08725697 0,08743868 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08725697 0,08740227 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08725697 0,0873659 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08810832 0,08818162 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,08810832 0,08814496 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,08810832 0,08810832 GO:0060538|skeletal muscle organ development,