pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/1022-0-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of focal adhesion formation GO:0051893 7 6 1,000 6,331E-06 0,01166884 ! regulation of Rho GTPase activity GO:0032319 6 6 1,000 6,331E-06 5,834E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 6,331E-06 3,89E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 8,861E-06 4,083E-03 ! cellular protein complex disassembly GO:0043624 8 7 1,000 8,861E-06 3,266E-03 GO:0043241|protein complex disassembly, ! negative regulation of signal transduction GO:0009968 71 71 2,000 1,038E-05 3,188E-03 ! regulation of stress fiber formation GO:0051492 9 8 1,000 1,181E-05 3,11E-03 ! negative regulation of cell communication GO:0010648 76 76 2,000 1,275E-05 2,938E-03 ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,518E-05 3,109E-03 ! regulation of actin filament bundle formation GO:0032231 10 9 1,000 1,518E-05 2,798E-03 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 1,897E-05 3,179E-03 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 2,318E-05 3,56E-03 ! mitotic spindle organization GO:0007052 11 11 1,000 2,318E-05 3,286E-03 ! negative regulation of translation GO:0017148 12 12 1,000 2,781E-05 3,661E-03 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,286E-05 4,037E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 3,286E-05 3,785E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,286E-05 3,562E-03 GO:0001952|regulation of cell-matrix adhesion, ! macromolecular complex disassembly GO:0032984 15 14 1,000 3,832E-05 3,924E-03 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,722E-05 5,55E-03 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 5,722E-05 5,273E-03 ! RNA export from nucleus GO:0006405 22 22 1,000 9,705E-05 8,517E-03 ! spindle organization GO:0007051 22 22 1,000 9,705E-05 8,13E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 9,705E-05 7,777E-03 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 1,159E-04 8,899E-03 ! cellular component disassembly GO:0022411 26 25 1,000 1,259E-04 9,284E-03 ! response to insulin stimulus GO:0032868 28 26 1,000 1,364E-04 9,668E-03 ! nuclear export GO:0051168 32 32 1,000 2,078E-04 0,01418294 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 2,349E-04 0,01545967 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 2,49E-04 0,0158266 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 2,636E-04 0,01619427 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 2,786E-04 0,01656258 ! RNA elongation GO:0006354 38 38 1,000 2,94E-04 0,01693145 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 2,94E-04 0,01641838 ! nucleotide-excision repair GO:0006289 40 39 1,000 3,098E-04 0,01679197 ! DNA catabolic process GO:0006308 41 40 1,000 3,26E-04 0,01716572 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 3,26E-04 0,0166889 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 3,426E-04 0,01706558 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 3,596E-04 0,01744222 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 3,949E-04 0,01866188 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 4,132E-04 0,01903608 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 4,132E-04 0,01857178 ! regulation of actin filament-based process GO:0032970 47 46 1,000 4,318E-04 0,01894814 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 4,318E-04 0,01850749 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 4,318E-04 0,01808686 ! positive regulation of ligase activity GO:0051351 47 46 1,000 4,318E-04 0,01768493 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 4,703E-04 0,01884401 ! regulation of ligase activity GO:0051340 50 49 1,000 4,902E-04 0,01922228 ! RNA transport GO:0050658 50 50 1,000 5,105E-04 0,01960034 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! transcription initiation GO:0006352 50 50 1,000 5,105E-04 0,01920033 ! RNA localization GO:0006403 52 52 1,000 5,522E-04 0,02035582 ! regulation of GTPase activity GO:0043087 53 52 1,000 5,522E-04 0,01995669 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 5,737E-04 0,02033454 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 6,179E-04 0,02148748 ! regulation of cell adhesion GO:0030155 56 55 1,000 6,179E-04 0,02108956 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 7,354E-04 0,02464401 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 7,602E-04 0,0250171 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 7,853E-04 0,02539006 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 8,367E-04 0,02658618 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 8,63E-04 0,02695739 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 8,897E-04 0,02732849 ! regulation of translation GO:0006417 69 69 1,000 9,722E-04 0,02937359 ! ribosome biogenesis GO:0042254 71 71 1,000 1,029E-03 0,03059425 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 1,058E-03 0,03095982 ! regulation of protein modification process GO:0031399 79 78 1,000 1,241E-03 0,03574306 ! nuclear transport GO:0051169 79 79 1,000 1,273E-03 0,03609671 GO:0006913|nucleocytoplasmic transport, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 1,65E-03 0,04606279 ! negative regulation of cell cycle GO:0045786 92 91 1,000 1,686E-03 0,04638138 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 1,953E-03 0,05293384 ! anti-apoptosis GO:0006916 100 99 1,000 1,993E-03 0,0532267 ! response to hormone stimulus GO:0009725 102 100 1,000 2,033E-03 0,05352138 ! rRNA transcription GO:0009303 5 5 0,000 3,629E-03 0,09421356 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 3,629E-03 0,09290504 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 3,629E-03 0,09163237 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 3,629E-03 0,09039409 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 3,629E-03 0,08918884 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 3,629E-03 0,0880153 ! reproductive cellular process GO:0048610 5 5 0,000 3,629E-03 0,08687224 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 3,629E-03 0,0857585 ! negative regulation of blood pressure GO:0045776 6 5 0,000 3,629E-03 0,08467295 ! prostate gland development GO:0030850 5 5 0,000 3,629E-03 0,08361453 ! metencephalon development GO:0022037 5 5 0,000 3,629E-03 0,08258226 ! water transport GO:0006833 5 5 0,000 3,629E-03 0,08157516 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 3,629E-03 0,08059232 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 3,629E-03 0,07963289 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 3,629E-03 0,07869603 ! glycerol metabolic process GO:0006071 5 5 0,000 3,629E-03 0,07778096 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 3,629E-03 0,07688693 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 3,629E-03 0,07601321 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 3,629E-03 0,07515913 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 3,629E-03 0,07432403 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 3,629E-03 0,07350728 ! filopodium assembly GO:0046847 7 5 0,000 3,629E-03 0,07270829 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 3,629E-03 0,07192648 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 3,629E-03 0,07116131 ! GTP metabolic process GO:0046039 5 5 0,000 3,629E-03 0,07041224 ! establishment of tissue polarity GO:0007164 5 5 0,000 3,629E-03 0,06967878 ! mRNA stabilization GO:0048255 5 5 0,000 3,629E-03 0,06896044 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 3,629E-03 0,06825676 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 3,629E-03 0,0675673 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 3,629E-03 0,06689163 ! social behavior GO:0035176 5 5 0,000 3,629E-03 0,06622933 ! macrophage chemotaxis GO:0048246 6 5 0,000 3,629E-03 0,06558003 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 3,629E-03 0,06494333 ! memory GO:0007613 5 5 0,000 3,629E-03 0,06431887 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 3,629E-03 0,06370631 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 3,629E-03 0,06310531 ! membrane hyperpolarization GO:0060081 5 5 0,000 3,629E-03 0,06251554 ! response to lipid GO:0033993 5 5 0,000 3,629E-03 0,06193669 ! erythrocyte maturation GO:0043249 5 5 0,000 3,629E-03 0,06136847 ! hippocampus development GO:0021766 6 5 0,000 3,629E-03 0,06081057 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 3,629E-03 0,06026273 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 3,629E-03 0,05972467 ! middle ear morphogenesis GO:0042474 5 5 0,000 3,629E-03 0,05919613 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 3,629E-03 0,05867687 ! mechanosensory behavior GO:0007638 5 5 0,000 3,629E-03 0,05816663 ! heart looping GO:0001947 5 5 0,000 3,629E-03 0,0576652 ! negative regulation of endocytosis GO:0045806 5 5 0,000 3,629E-03 0,05717233 ! response to interferon-gamma GO:0034341 5 5 0,000 3,629E-03 0,05668782 ! pseudouridine synthesis GO:0001522 5 5 0,000 3,629E-03 0,05621145 ! endocrine pancreas development GO:0031018 5 5 0,000 3,629E-03 0,05574302 ! pH reduction GO:0045851 5 5 0,000 3,629E-03 0,05528234 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 3,629E-03 0,0548292 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 3,629E-03 0,05438344 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 3,629E-03 0,05394486 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 3,629E-03 0,0535133 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 3,629E-03 0,05308859 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 3,629E-03 0,05267057 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 3,629E-03 0,05225908 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 3,629E-03 0,05185398 ! adrenal gland development GO:0030325 5 5 0,000 3,629E-03 0,0514551 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 3,629E-03 0,05106231 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 3,629E-03 0,05067548 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 3,629E-03 0,05029446 ! astrocyte differentiation GO:0048708 5 5 0,000 3,629E-03 0,04991913 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 3,629E-03 0,04954935 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 3,629E-03 0,04918502 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 3,629E-03 0,04882601 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 3,629E-03 0,04847219 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 3,629E-03 0,04812347 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 3,629E-03 0,04777973 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 3,629E-03 0,04744087 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 3,629E-03 0,04710678 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 3,629E-03 0,04677736 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 3,629E-03 0,04645252 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 3,629E-03 0,04613216 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 3,629E-03 0,04581618 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 3,629E-03 0,04550451 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 3,629E-03 0,04519705 ! response to ATP GO:0033198 5 5 0,000 3,629E-03 0,04489371 ! regulation of type I interferon production GO:0032479 5 5 0,000 3,629E-03 0,04459442 ! regulation of appetite GO:0032098 5 5 0,000 3,629E-03 0,04429909 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 3,629E-03 0,04400765 ! paraxial mesoderm development GO:0048339 5 5 0,000 3,629E-03 0,04372002 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 3,629E-03 0,04343612 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 3,629E-03 0,04315589 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 3,629E-03 0,04287925 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,629E-03 0,04260613 ! receptor clustering GO:0043113 5 5 0,000 3,629E-03 0,04233647 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 3,629E-03 0,04207021 ! fear response GO:0042596 5 5 0,000 3,629E-03 0,04180727 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 3,629E-03 0,04154759 ! lens development in camera-type eye GO:0002088 5 5 0,000 3,629E-03 0,04129113 ! retinol metabolic process GO:0042572 5 5 0,000 3,629E-03 0,04103781 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 3,629E-03 0,04078758 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 3,629E-03 0,04054038 ! positive regulation of exocytosis GO:0045921 6 5 0,000 3,629E-03 0,04029616 ! parturition GO:0007567 5 5 0,000 3,629E-03 0,04005487 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,629E-03 0,03981645 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 3,629E-03 0,03958084 ! Schwann cell differentiation GO:0014037 5 5 0,000 3,629E-03 0,03934802 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 3,629E-03 0,03911791 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 3,629E-03 0,03889048 ! protein heterooligomerization GO:0051291 5 5 0,000 3,629E-03 0,03866568 ! regulation of gliogenesis GO:0014013 5 5 0,000 3,629E-03 0,03844346 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 3,629E-03 0,03822379 ! response to UV-B GO:0010224 5 5 0,000 3,629E-03 0,03800661 ! oligodendrocyte development GO:0014003 5 5 0,000 3,629E-03 0,03779188 ! hyaluronan metabolic process GO:0030212 5 5 0,000 3,629E-03 0,03757957 ! activated T cell proliferation GO:0050798 5 5 0,000 3,629E-03 0,03736962 ! interaction with symbiont GO:0051702 5 5 0,000 3,629E-03 0,03716202 ! cellular extravasation GO:0045123 5 5 0,000 3,629E-03 0,0369567 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 3,629E-03 0,03675364 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 3,629E-03 0,0365528 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 3,629E-03 0,03635415 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 3,629E-03 0,03615764 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 3,629E-03 0,03596324 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 3,629E-03 0,03577092 ! response to amine stimulus GO:0014075 5 5 0,000 3,629E-03 0,03558065 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 3,629E-03 0,0353924 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 3,629E-03 0,03520612 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 3,629E-03 0,03502179 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 3,629E-03 0,03483939 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 3,629E-03 0,03465887 ! neuron recognition GO:0008038 5 5 0,000 3,629E-03 0,03448022 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 3,629E-03 0,0343034 ! decidualization GO:0046697 5 5 0,000 3,629E-03 0,03412838 ! hair follicle maturation GO:0048820 5 5 0,000 3,629E-03 0,03395514 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 3,629E-03 0,03378365 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 3,629E-03 0,03361388 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 3,629E-03 0,03344581 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 3,629E-03 0,03327942 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 3,629E-03 0,03311467 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 3,629E-03 0,03295154 ! postreplication repair GO:0006301 5 5 0,000 3,629E-03 0,03279001 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 3,629E-03 0,03263006 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 3,629E-03 0,03247166 ! histone methylation GO:0016571 5 5 0,000 3,629E-03 0,0323148 ! DNA methylation GO:0006306 5 5 0,000 3,629E-03 0,03215944 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,629E-03 0,03200556 ! T cell lineage commitment GO:0002360 5 5 0,000 3,629E-03 0,03185316 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 3,629E-03 0,03170219 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 3,629E-03 0,03155265 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 3,629E-03 0,03140452 ! intracellular cholesterol transport GO:0032367 5 5 0,000 3,629E-03 0,03125777 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 3,629E-03 0,03111239 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 3,629E-03 0,03096835 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 3,629E-03 0,03082563 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 3,629E-03 0,03068423 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 3,629E-03 0,03054412 ! sterol catabolic process GO:0016127 5 5 0,000 3,629E-03 0,03040529 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 3,629E-03 0,0302677 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 3,629E-03 0,03013136 ! detection of biotic stimulus GO:0009595 5 5 0,000 3,629E-03 0,02999625 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 3,629E-03 0,02986233 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 3,629E-03 0,02972961 ! zymogen activation GO:0031638 5 5 0,000 3,629E-03 0,02959807 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 3,629E-03 0,02946768 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 3,629E-03 0,02933843 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 3,629E-03 0,02921032 ! peptidyl-lysine modification GO:0018205 5 5 0,000 3,629E-03 0,02908332 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 3,629E-03 0,02895741 ! peptidyl-histidine modification GO:0018202 5 5 0,000 3,629E-03 0,0288326 ! nucleosome positioning GO:0016584 5 5 0,000 3,629E-03 0,02870885 ! regulation of isotype switching GO:0045191 5 5 0,000 3,629E-03 0,02858617 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 3,629E-03 0,02846452 ! negative regulation of neurological system process GO:0031645 5 5 0,000 3,629E-03 0,02834391 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 3,629E-03 0,02822432 ! glutathione biosynthetic process GO:0006750 5 5 0,000 3,629E-03 0,02810573 ! NADPH regeneration GO:0006740 5 5 0,000 3,629E-03 0,02798813 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 3,629E-03 0,02787151 ! positive regulation of epidermis development GO:0045684 5 5 0,000 3,629E-03 0,02775586 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 3,629E-03 0,02764117 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 3,629E-03 0,02752742 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 3,629E-03 0,0274146 ! sarcomere organization GO:0045214 5 5 0,000 3,629E-03 0,02730271 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 3,629E-03 0,02719172 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 3,629E-03 0,02708163 ! negative regulation of glucose transport GO:0010829 5 5 0,000 3,629E-03 0,02697243 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 3,629E-03 0,02686411 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 3,629E-03 0,02675665 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 3,629E-03 0,02665005 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 3,629E-03 0,0265443 ! spleen development GO:0048536 5 5 0,000 3,629E-03 0,02643938 ! male genitalia development GO:0030539 5 5 0,000 3,629E-03 0,02633529 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 3,629E-03 0,02623201 ! quaternary ammonium group transport GO:0015697 5 5 0,000 3,629E-03 0,02612954 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 3,629E-03 0,02602787 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 3,629E-03 0,02592699 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 3,629E-03 0,02582688 ! removal of superoxide radicals GO:0019430 6 5 0,000 3,629E-03 0,02572755 ! myeloid cell homeostasis GO:0002262 5 5 0,000 3,629E-03 0,02562898 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 3,629E-03 0,02553116 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 3,629E-03 0,02543408 ! ATP catabolic process GO:0006200 5 5 0,000 3,629E-03 0,02533774 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,629E-03 0,02524212 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 3,629E-03 0,02514723 ! blastocyst formation GO:0001825 5 5 0,000 3,629E-03 0,02505304 ! regulation of fibrinolysis GO:0051917 5 5 0,000 3,629E-03 0,02495956 ! embryonic gut development GO:0048566 5 5 0,000 3,629E-03 0,02486678 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 3,629E-03 0,02477468 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 3,629E-03 0,02468326 ! activation of innate immune response GO:0002218 5 5 0,000 3,629E-03 0,02459251 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 3,629E-03 0,02450243 ! catecholamine transport GO:0051937 5 5 0,000 3,629E-03 0,024413 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 3,629E-03 0,02432423 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 3,629E-03 0,0242361 ! muscle adaptation GO:0043500 5 5 0,000 3,629E-03 0,0241486 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 3,629E-03 0,02406174 ! embryonic heart tube development GO:0035050 5 5 0,000 3,629E-03 0,02397549 ! cardiac cell differentiation GO:0035051 6 5 0,000 3,629E-03 0,02388987 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 3,629E-03 0,02380485 ! defense response to fungus GO:0050832 5 5 0,000 3,629E-03 0,02372044 ! lysogeny GO:0030069 5 5 0,000 3,629E-03 0,02363662 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 3,629E-03 0,02355339 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 3,629E-03 0,02347075 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 3,629E-03 0,02338868 ! response to nicotine GO:0035094 5 5 0,000 3,629E-03 0,02330719 ! establishment of cell polarity GO:0030010 5 5 0,000 3,629E-03 0,02322626 ! mitochondrion localization GO:0051646 5 5 0,000 3,629E-03 0,02314589 ! nucleus localization GO:0051647 5 5 0,000 3,629E-03 0,02306608 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 3,629E-03 0,02298681 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 4,354E-03 0,02748172 ! axon extension GO:0048675 7 6 0,000 4,354E-03 0,02738792 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 4,354E-03 0,02729477 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 4,354E-03 0,02720224 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 4,354E-03 0,02711034 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 4,354E-03 0,02701906 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 4,354E-03 0,02692839 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 4,354E-03 0,02683833 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 4,354E-03 0,02674887 ! virus-host interaction GO:0019048 6 6 0,000 4,354E-03 0,02666001 ! regulation of S phase GO:0033261 6 6 0,000 4,354E-03 0,02657173 ! myotube differentiation GO:0014902 6 6 0,000 4,354E-03 0,02648403 ! regulation of B cell proliferation GO:0030888 6 6 0,000 4,354E-03 0,02639691 ! bone remodeling GO:0046849 6 6 0,000 4,354E-03 0,02631037 ! N-glycan processing GO:0006491 6 6 0,000 4,354E-03 0,02622438 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,354E-03 0,02613896 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 4,354E-03 0,0260541 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 4,354E-03 0,02596978 ! retina development in camera-type eye GO:0060041 6 6 0,000 4,354E-03 0,02588601 ! RNA methylation GO:0001510 6 6 0,000 4,354E-03 0,02580277 ! cartilage condensation GO:0001502 7 6 0,000 4,354E-03 0,02572007 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 4,354E-03 0,0256379 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 4,354E-03 0,02555625 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 4,354E-03 0,02547512 ! artery development GO:0060840 6 6 0,000 4,354E-03 0,0253945 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 4,354E-03 0,02531439 ! bile acid metabolic process GO:0008206 6 6 0,000 4,354E-03 0,02523478 ! androgen metabolic process GO:0008209 6 6 0,000 4,354E-03 0,02515568 ! estrogen metabolic process GO:0008210 6 6 0,000 4,354E-03 0,02507707 ! limbic system development GO:0021761 7 6 0,000 4,354E-03 0,02499895 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 4,354E-03 0,02492131 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 4,354E-03 0,02484415 ! positive regulation of heart contraction GO:0045823 6 6 0,000 4,354E-03 0,02476747 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 4,354E-03 0,02469127 ! pathogenesis GO:0009405 6 6 0,000 4,354E-03 0,02461553 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 4,354E-03 0,02454025 ! positive regulation of cell growth GO:0030307 6 6 0,000 4,354E-03 0,02446543 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 4,354E-03 0,02439107 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 4,354E-03 0,02431716 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 4,354E-03 0,02424369 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 4,354E-03 0,02417067 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 4,354E-03 0,02409808 ! arginine metabolic process GO:0006525 6 6 0,000 4,354E-03 0,02402593 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 4,354E-03 0,02395421 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 4,354E-03 0,02388292 ! glutamate catabolic process GO:0006538 7 6 0,000 4,354E-03 0,02381205 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 4,354E-03 0,0237416 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 4,354E-03 0,02367157 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 4,354E-03 0,02360195 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 4,354E-03 0,02353273 ! ER overload response GO:0006983 6 6 0,000 4,354E-03 0,02346392 ! V(D)J recombination GO:0033151 6 6 0,000 4,354E-03 0,02339551 ! focal adhesion formation GO:0048041 7 6 0,000 4,354E-03 0,0233275 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,354E-03 0,02325989 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 4,354E-03 0,02319266 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 4,354E-03 0,02312583 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 4,354E-03 0,02305937 ! regulation of heart rate GO:0002027 6 6 0,000 4,354E-03 0,0229933 ! lipid digestion GO:0044241 6 6 0,000 4,354E-03 0,0229276 ! asymmetric protein localization GO:0008105 6 6 0,000 4,354E-03 0,02286228 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 4,354E-03 0,02279733 ! phagocytosis, engulfment GO:0006911 6 6 0,000 4,354E-03 0,02273275 ! Rac protein signal transduction GO:0016601 6 6 0,000 4,354E-03 0,02266854 ! regulation of vascular permeability GO:0043114 6 6 0,000 4,354E-03 0,02260468 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 4,354E-03 0,02254118 ! ruffle organization GO:0031529 6 6 0,000 4,354E-03 0,02247804 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 4,354E-03 0,02241526 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 4,354E-03 0,02235282 ! retinoic acid metabolic process GO:0042573 6 6 0,000 4,354E-03 0,02229073 ! neutral amino acid transport GO:0015804 6 6 0,000 4,354E-03 0,02222898 ! L-amino acid transport GO:0015807 6 6 0,000 4,354E-03 0,02216757 ! bone mineralization GO:0030282 6 6 0,000 4,354E-03 0,02210651 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 4,354E-03 0,02204577 ! negative regulation of ossification GO:0030279 6 6 0,000 4,354E-03 0,02198537 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 4,354E-03 0,0219253 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 4,354E-03 0,02186556 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 4,354E-03 0,02180615 ! purine base biosynthetic process GO:0009113 6 6 0,000 4,354E-03 0,02174705 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 4,354E-03 0,02168827 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 4,354E-03 0,02162982 ! regulation of phagocytosis GO:0050764 6 6 0,000 4,354E-03 0,02157167 ! regulation of organ growth GO:0046620 6 6 0,000 4,354E-03 0,02151384 ! regulation of circadian rhythm GO:0042752 6 6 0,000 4,354E-03 0,02145631 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 4,354E-03 0,0213991 ! response to dsRNA GO:0043331 6 6 0,000 4,354E-03 0,02134219 ! DNA unwinding during replication GO:0006268 6 6 0,000 4,354E-03 0,02128557 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 4,354E-03 0,02122926 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 4,354E-03 0,02117325 ! genitalia development GO:0048806 6 6 0,000 4,354E-03 0,02111753 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 4,354E-03 0,0210621 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 4,354E-03 0,02100697 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 4,354E-03 0,02095212 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 4,354E-03 0,02089756 ! multicellular organismal aging GO:0010259 6 6 0,000 4,354E-03 0,02084328 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 4,354E-03 0,02078928 ! erythrocyte development GO:0048821 6 6 0,000 4,354E-03 0,02073556 ! renal water homeostasis GO:0003091 6 6 0,000 4,354E-03 0,02068212 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 4,354E-03 0,02062895 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 4,354E-03 0,02057606 ! ribosome assembly GO:0042255 6 6 0,000 4,354E-03 0,02052343 ! diencephalon development GO:0021536 6 6 0,000 4,354E-03 0,02047108 ! fucose catabolic process GO:0019317 6 6 0,000 4,354E-03 0,02041899 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 4,354E-03 0,02036716 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 4,354E-03 0,0203156 ! regulation of lipid transport GO:0032368 6 6 0,000 4,354E-03 0,0202643 ! regulation of cell division GO:0051302 6 6 0,000 4,354E-03 0,02021325 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 4,354E-03 0,02016247 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 4,354E-03 0,02011193 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 4,354E-03 0,02006165 ! salivary gland morphogenesis GO:0007435 6 6 0,000 4,354E-03 0,02001162 ! neuroblast proliferation GO:0007405 6 6 0,000 4,354E-03 0,01996184 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 4,354E-03 0,01991231 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 4,354E-03 0,01986302 ! regulation of glucose transport GO:0010827 6 6 0,000 4,354E-03 0,01981398 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 4,354E-03 0,01976518 ! methionine biosynthetic process GO:0009086 6 6 0,000 4,354E-03 0,01971661 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 4,354E-03 0,01966829 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 4,354E-03 0,0196202 ! thymus development GO:0048538 6 6 0,000 4,354E-03 0,01957235 ! lymph node development GO:0048535 6 6 0,000 4,354E-03 0,01952472 ! organic cation transport GO:0015695 6 6 0,000 4,354E-03 0,01947733 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 4,354E-03 0,01943017 ! regulation of RNA splicing GO:0043484 6 6 0,000 4,354E-03 0,01938324 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 4,354E-03 0,01933653 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 4,354E-03 0,01929005 ! sperm-egg recognition GO:0035036 7 6 0,000 4,354E-03 0,01924379 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 4,354E-03 0,01919775 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 4,354E-03 0,01915194 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 4,354E-03 0,01910634 ! alditol metabolic process GO:0019400 6 6 0,000 4,354E-03 0,01906095 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 4,354E-03 0,01901579 ! regulation of amino acid transport GO:0051955 6 6 0,000 4,354E-03 0,01897083 ! maternal placenta development GO:0001893 6 6 0,000 4,354E-03 0,01892609 ! regulation of embryonic development GO:0045995 6 6 0,000 4,354E-03 0,01888156 ! negative regulation of immune effector process GO:0002698 6 6 0,000 4,354E-03 0,01883723 ! localization within membrane GO:0051668 6 6 0,000 4,354E-03 0,01879312 ! respiratory burst GO:0045730 7 7 0,000 5,078E-03 0,02186772 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 5,078E-03 0,02181674 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 5,078E-03 0,02176601 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 5,078E-03 0,02171551 ! positive regulation of blood pressure GO:0045777 7 7 0,000 5,078E-03 0,02166524 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 5,078E-03 0,0216152 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 5,078E-03 0,0215654 ! regulation of chemokine production GO:0032642 7 7 0,000 5,078E-03 0,02151582 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 5,078E-03 0,02146648 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 5,078E-03 0,02141735 ! hair follicle morphogenesis GO:0031069 7 7 0,000 5,078E-03 0,02136845 ! gene silencing by RNA GO:0031047 7 7 0,000 5,078E-03 0,02131978 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 5,078E-03 0,02127133 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 5,078E-03 0,02122309 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 5,078E-03 0,02117508 ! keratinocyte proliferation GO:0043616 7 7 0,000 5,078E-03 0,02112728 ! axis specification GO:0009798 7 7 0,000 5,078E-03 0,02107969 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 5,078E-03 0,02103232 ! visual behavior GO:0007632 7 7 0,000 5,078E-03 0,02098516 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 5,078E-03 0,02093822 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 5,078E-03 0,02089148 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 5,078E-03 0,02084495 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 5,078E-03 0,02079863 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 5,078E-03 0,02075251 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 5,078E-03 0,0207066 ! endothelial cell differentiation GO:0045446 7 7 0,000 5,078E-03 0,02066089 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 5,078E-03 0,02061538 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 5,078E-03 0,02057007 ! digestive system development GO:0055123 7 7 0,000 5,078E-03 0,02052496 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 5,078E-03 0,02048005 ! regulation of exit from mitosis GO:0007096 7 7 0,000 5,078E-03 0,02043533 ! protein targeting to ER GO:0045047 8 7 0,000 5,078E-03 0,02039081 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 5,078E-03 0,02034649 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 5,078E-03 0,02030235 ! endoderm development GO:0007492 7 7 0,000 5,078E-03 0,02025841 ! regulation of defense response to virus GO:0050688 7 7 0,000 5,078E-03 0,02021465 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 5,078E-03 0,02017108 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 5,078E-03 0,02012771 ! response to hexose stimulus GO:0009746 7 7 0,000 5,078E-03 0,02008451 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 5,078E-03 0,02004151 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 5,078E-03 0,01999868 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 5,078E-03 0,01995604 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 5,078E-03 0,01991358 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 5,078E-03 0,0198713 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 5,078E-03 0,0198292 ! complement activation, alternative pathway GO:0006957 7 7 0,000 5,078E-03 0,01978728 ! arachidonic acid secretion GO:0050482 7 7 0,000 5,078E-03 0,01974553 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 5,078E-03 0,01970396 ! response to X-ray GO:0010165 7 7 0,000 5,078E-03 0,01966257 ! regulation of intracellular pH GO:0051453 7 7 0,000 5,078E-03 0,01962135 ! UV protection GO:0009650 7 7 0,000 5,078E-03 0,0195803 ! DNA integration GO:0015074 7 7 0,000 5,078E-03 0,01953942 ! myofibril assembly GO:0030239 7 7 0,000 5,078E-03 0,01949872 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 5,078E-03 0,01945818 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 5,078E-03 0,01941781 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 5,078E-03 0,01937761 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 5,078E-03 0,01933757 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 5,078E-03 0,0192977 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 5,078E-03 0,01925799 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 5,078E-03 0,01921845 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 5,078E-03 0,01917906 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 5,078E-03 0,01913984 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 5,078E-03 0,01910078 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 5,078E-03 0,01906188 ! axon cargo transport GO:0008088 7 7 0,000 5,078E-03 0,01902314 ! eating behavior GO:0042755 7 7 0,000 5,078E-03 0,01898455 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 5,078E-03 0,01894612 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 5,078E-03 0,01890784 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 5,078E-03 0,01886972 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 5,078E-03 0,01883176 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 5,078E-03 0,01879394 ! cranial nerve development GO:0021545 7 7 0,000 5,078E-03 0,01875628 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 5,078E-03 0,01871877 ! induction of an organ GO:0001759 7 7 0,000 5,078E-03 0,0186814 ! leukocyte activation during immune response GO:0002366 7 7 0,000 5,078E-03 0,01864419 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 5,078E-03 0,01860712 ! autonomic nervous system development GO:0048483 7 7 0,000 5,078E-03 0,0185702 ! intracellular lipid transport GO:0032365 7 7 0,000 5,078E-03 0,01853343 ! detection of chemical stimulus GO:0009593 8 7 0,000 5,078E-03 0,0184968 ! platelet activation GO:0030168 8 7 0,000 5,078E-03 0,01846032 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 5,078E-03 0,01842398 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 5,078E-03 0,01838779 ! natural killer cell activation GO:0030101 7 7 0,000 5,078E-03 0,01835173 ! response to gamma radiation GO:0010332 8 7 0,000 5,078E-03 0,01831582 ! NADP metabolic process GO:0006739 7 7 0,000 5,078E-03 0,01828005 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 5,078E-03 0,01824441 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 5,078E-03 0,01820892 ! ubiquinone metabolic process GO:0006743 7 7 0,000 5,078E-03 0,01817356 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 5,078E-03 0,01813834 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 5,078E-03 0,01810326 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 5,078E-03 0,01806831 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 5,078E-03 0,01803349 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 5,078E-03 0,01799881 ! regulation of ATPase activity GO:0043462 7 7 0,000 5,078E-03 0,01796427 ! cell-cell recognition GO:0009988 8 7 0,000 5,078E-03 0,01792985 ! hormone catabolic process GO:0042447 7 7 0,000 5,078E-03 0,01789557 ! dopamine metabolic process GO:0042417 7 7 0,000 5,078E-03 0,01786142 ! cAMP biosynthetic process GO:0006171 7 7 0,000 5,078E-03 0,0178274 ! oxygen transport GO:0015671 7 7 0,000 5,078E-03 0,0177935 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 5,078E-03 0,01775974 ! regulation of mRNA stability GO:0043488 7 7 0,000 5,078E-03 0,0177261 ! biogenic amine catabolic process GO:0042402 7 7 0,000 5,078E-03 0,0176926 ! regulation of axon extension GO:0030516 7 7 0,000 5,078E-03 0,01765921 ! cell killing GO:0001906 7 7 0,000 5,078E-03 0,01762596 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 5,078E-03 0,01759283 ! adult feeding behavior GO:0008343 7 7 0,000 5,078E-03 0,01755982 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 5,078E-03 0,01752693 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 5,078E-03 0,01749417 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 5,078E-03 0,01746154 ! negative regulation of T cell activation GO:0050868 7 7 0,000 5,078E-03 0,01742902 ! response to cold GO:0009409 7 7 0,000 5,078E-03 0,01739662 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 5,802E-03 0,0198392 ! negative regulation of muscle development GO:0048635 8 8 0,000 5,802E-03 0,01980246 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 5,802E-03 0,01976586 ! positive regulation of translation GO:0045727 8 8 0,000 5,802E-03 0,01972939 ! positive regulation of cell killing GO:0031343 8 8 0,000 5,802E-03 0,01969305 ! superoxide anion generation GO:0042554 8 8 0,000 5,802E-03 0,01965685 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 5,802E-03 0,01962079 ! cGMP metabolic process GO:0046068 8 8 0,000 5,802E-03 0,01958485 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 5,802E-03 0,01954905 ! 'de novo' protein folding GO:0006458 8 8 0,000 5,802E-03 0,01951337 ! dicarboxylic acid transport GO:0006835 8 8 0,000 5,802E-03 0,01947783 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 5,802E-03 0,01944241 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 5,802E-03 0,01940713 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 5,802E-03 0,01937197 ! zinc ion transport GO:0006829 8 8 0,000 5,802E-03 0,01933694 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 5,802E-03 0,01930204 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 5,802E-03 0,01926726 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 5,802E-03 0,0192326 ! cardiac muscle contraction GO:0060048 8 8 0,000 5,802E-03 0,01919808 ! lipid localization GO:0010876 8 8 0,000 5,802E-03 0,01916367 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 5,802E-03 0,01912939 ! response to cAMP GO:0051591 8 8 0,000 5,802E-03 0,01909523 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 5,802E-03 0,01906119 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 5,802E-03 0,01902727 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 5,802E-03 0,01899348 ! negative regulation of ion transport GO:0043271 8 8 0,000 5,802E-03 0,0189598 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 5,802E-03 0,01892624 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 5,802E-03 0,01889281 ! sensory perception of taste GO:0050909 8 8 0,000 5,802E-03 0,01885949 ! organelle fusion GO:0048284 8 8 0,000 5,802E-03 0,01882628 ! pancreas development GO:0031016 8 8 0,000 5,802E-03 0,0187932 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 5,802E-03 0,01876022 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 5,802E-03 0,01872737 ! negative regulation of proteolysis GO:0045861 8 8 0,000 5,802E-03 0,01869463 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 5,802E-03 0,018662 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 5,802E-03 0,01862949 ! sperm motility GO:0030317 8 8 0,000 5,802E-03 0,01859709 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 5,802E-03 0,01856481 ! DNA duplex unwinding GO:0032508 8 8 0,000 5,802E-03 0,01853263 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 5,802E-03 0,01850057 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 5,802E-03 0,01846862 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 5,802E-03 0,01843677 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 5,802E-03 0,01840504 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 5,802E-03 0,01837342 ! Golgi organization GO:0007030 8 8 0,000 5,802E-03 0,0183419 ! cell-cell junction assembly GO:0007043 8 8 0,000 5,802E-03 0,01831049 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 5,802E-03 0,01827919 ! fructose metabolic process GO:0006000 8 8 0,000 5,802E-03 0,018248 ! mannose metabolic process GO:0006013 9 8 0,000 5,802E-03 0,01821691 ! NAD metabolic process GO:0019674 8 8 0,000 5,802E-03 0,01818593 ! sex determination GO:0007530 8 8 0,000 5,802E-03 0,01815506 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 5,802E-03 0,01812428 ! plasma membrane fusion GO:0045026 8 8 0,000 5,802E-03 0,01809362 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 5,802E-03 0,01806305 ! response to fungus GO:0009620 8 8 0,000 5,802E-03 0,01803259 ! stem cell differentiation GO:0048863 8 8 0,000 5,802E-03 0,01800224 ! alpha-beta T cell activation GO:0046631 8 8 0,000 5,802E-03 0,01797198 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 5,802E-03 0,01794183 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 5,802E-03 0,01791177 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 5,802E-03 0,01788182 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 5,802E-03 0,01785197 ! regulation of vasodilation GO:0042312 8 8 0,000 5,802E-03 0,01782221 ! vasoconstriction GO:0042310 8 8 0,000 5,802E-03 0,01779256 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 5,802E-03 0,017763 ! muscle cell development GO:0055001 8 8 0,000 5,802E-03 0,01773355 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 5,802E-03 0,01770419 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 5,802E-03 0,01767492 ! sensory perception of pain GO:0019233 8 8 0,000 5,802E-03 0,01764576 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 5,802E-03 0,01761669 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 5,802E-03 0,01758771 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 5,802E-03 0,01755883 ! chromatin silencing GO:0006342 8 8 0,000 5,802E-03 0,01753005 ! tissue regeneration GO:0042246 8 8 0,000 5,802E-03 0,01750136 ! salivary gland development GO:0007431 8 8 0,000 5,802E-03 0,01747276 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 5,802E-03 0,01744425 ! T cell homeostasis GO:0043029 8 8 0,000 5,802E-03 0,01741584 ! peptide biosynthetic process GO:0043043 9 8 0,000 5,802E-03 0,01738753 ! peptidyl-serine modification GO:0018209 8 8 0,000 5,802E-03 0,0173593 ! water homeostasis GO:0030104 8 8 0,000 5,802E-03 0,01733116 ! cofactor transport GO:0051181 8 8 0,000 5,802E-03 0,01730312 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 5,802E-03 0,01727517 ! acid secretion GO:0046717 8 8 0,000 5,802E-03 0,0172473 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 5,802E-03 0,01721953 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 5,802E-03 0,01719185 ! protein-chromophore linkage GO:0018298 9 8 0,000 5,802E-03 0,01716425 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 5,802E-03 0,01713674 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 5,802E-03 0,01710932 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 5,802E-03 0,01708199 ! regulation of RNA stability GO:0043487 8 8 0,000 5,802E-03 0,01705475 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 5,802E-03 0,01702759 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 5,802E-03 0,01700052 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 5,802E-03 0,01697354 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 5,802E-03 0,01694664 ! regulation of organic acid transport GO:0032890 8 8 0,000 5,802E-03 0,01691982 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 5,802E-03 0,01689309 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 5,802E-03 0,01686645 ! regulation of multi-organism process GO:0043900 8 8 0,000 5,802E-03 0,01683989 ! positive regulation of amine transport GO:0051954 8 8 0,000 5,802E-03 0,01681341 ! developmental induction GO:0031128 8 8 0,000 5,802E-03 0,01678701 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 5,802E-03 0,0167607 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 5,802E-03 0,01673447 ! actin filament polymerization GO:0030041 9 8 0,000 5,802E-03 0,01670833 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 5,802E-03 0,01668226 ! peptide hormone processing GO:0016486 8 8 0,000 5,802E-03 0,01665627 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 5,802E-03 0,01663037 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 5,802E-03 0,01660455 ! lactation GO:0007595 10 9 0,000 6,526E-03 0,01864573 ! embryonic pattern specification GO:0009880 10 9 0,000 6,526E-03 0,01861687 ! positive regulation of cell size GO:0045793 9 9 0,000 6,526E-03 0,01858809 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 6,526E-03 0,01855941 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 6,526E-03 0,01853081 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 6,526E-03 0,0185023 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 6,526E-03 0,01847388 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 6,526E-03 0,01844555 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 6,526E-03 0,0184173 ! viral genome replication GO:0019079 9 9 0,000 6,526E-03 0,01838914 ! phospholipid catabolic process GO:0009395 9 9 0,000 6,526E-03 0,01836106 ! copper ion transport GO:0006825 9 9 0,000 6,526E-03 0,01833307 ! lipid phosphorylation GO:0046834 9 9 0,000 6,526E-03 0,01830517 ! aminoglycan catabolic process GO:0006026 9 9 0,000 6,526E-03 0,01827735 ! Golgi vesicle budding GO:0048194 9 9 0,000 6,526E-03 0,01824962 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 6,526E-03 0,01822196 ! RNA polyadenylation GO:0043631 9 9 0,000 6,526E-03 0,0181944 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 6,526E-03 0,01816691 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 6,526E-03 0,01813951 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 6,526E-03 0,01811219 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 6,526E-03 0,01808496 ! phospholipid efflux GO:0033700 9 9 0,000 6,526E-03 0,0180578 ! response to alkaloid GO:0043279 10 9 0,000 6,526E-03 0,01803073 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 6,526E-03 0,01800374 ! cytokine biosynthetic process GO:0042089 9 9 0,000 6,526E-03 0,01797683 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 6,526E-03 0,01794999 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 6,526E-03 0,01792324 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 6,526E-03 0,01789657 ! response to ethanol GO:0045471 9 9 0,000 6,526E-03 0,01786998 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 6,526E-03 0,01784347 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 6,526E-03 0,01781703 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 6,526E-03 0,01779068 ! methionine metabolic process GO:0006555 9 9 0,000 6,526E-03 0,0177644 ! glutamine metabolic process GO:0006541 9 9 0,000 6,526E-03 0,0177382 ! cerebral cortex development GO:0021987 9 9 0,000 6,526E-03 0,01771207 ! response to osmotic stress GO:0006970 9 9 0,000 6,526E-03 0,01768602 ! pigmentation during development GO:0048066 9 9 0,000 6,526E-03 0,01766005 ! reverse cholesterol transport GO:0043691 9 9 0,000 6,526E-03 0,01763416 ! central nervous system neuron development GO:0021954 10 9 0,000 6,526E-03 0,01760834 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 6,526E-03 0,0175826 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 6,526E-03 0,01755693 ! substrate-bound cell migration GO:0006929 9 9 0,000 6,526E-03 0,01753134 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 6,526E-03 0,01750582 ! negative regulation of caspase activity GO:0043154 9 9 0,000 6,526E-03 0,01748037 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 6,526E-03 0,017455 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 6,526E-03 0,01742971 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 6,526E-03 0,01740448 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 6,526E-03 0,01737933 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 6,526E-03 0,01735425 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 6,526E-03 0,01732925 ! behavioral interaction between organisms GO:0051705 9 9 0,000 6,526E-03 0,01730431 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 6,526E-03 0,01727945 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 6,526E-03 0,01725466 ! DNA replication initiation GO:0006270 9 9 0,000 6,526E-03 0,01722994 ! prostaglandin metabolic process GO:0006693 9 9 0,000 6,526E-03 0,01720529 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 6,526E-03 0,01718071 ! regulation of cellular pH GO:0030641 9 9 0,000 6,526E-03 0,0171562 ! histone acetylation GO:0016573 9 9 0,000 6,526E-03 0,01713176 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 6,526E-03 0,01710739 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 6,526E-03 0,01708309 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 6,526E-03 0,01705886 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 6,526E-03 0,0170347 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 6,526E-03 0,0170106 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 6,526E-03 0,01698658 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 6,526E-03 0,01696262 ! negative regulation of protein secretion GO:0050709 9 9 0,000 6,526E-03 0,01693873 ! regulation of leukocyte migration GO:0002685 9 9 0,000 6,526E-03 0,0169149 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 6,526E-03 0,01689115 ! collagen catabolic process GO:0030574 9 9 0,000 6,526E-03 0,01686746 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 6,526E-03 0,01684383 ! purine base metabolic process GO:0006144 9 9 0,000 6,526E-03 0,01682027 ! gas transport GO:0015669 9 9 0,000 6,526E-03 0,01679678 ! cholesterol efflux GO:0033344 9 9 0,000 6,526E-03 0,01677336 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 6,526E-03 0,01675 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 6,526E-03 0,0167267 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 6,526E-03 0,01670347 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 6,526E-03 0,0166803 ! defense response to virus GO:0051607 9 9 0,000 6,526E-03 0,0166572 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 6,526E-03 0,01663416 ! actin filament-based movement GO:0030048 9 9 0,000 6,526E-03 0,01661118 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 6,526E-03 0,01658827 ! protein import into nucleus, docking GO:0000059 10 10 0,000 7,248E-03 0,01840067 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 7,248E-03 0,01837536 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 7,248E-03 0,01835012 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 7,248E-03 0,01832495 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 7,248E-03 0,01829985 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 7,248E-03 0,01827481 ! neuron maturation GO:0042551 10 10 0,000 7,248E-03 0,01824985 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 7,248E-03 0,01822495 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 7,248E-03 0,01820012 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 7,248E-03 0,01817536 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 7,248E-03 0,01815066 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 7,248E-03 0,01812604 ! hormone secretion GO:0046879 10 10 0,000 7,248E-03 0,01810148 ! glucosamine metabolic process GO:0006041 10 10 0,000 7,248E-03 0,01807698 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 7,248E-03 0,01805255 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 7,248E-03 0,01802819 ! inositol metabolic process GO:0006020 10 10 0,000 7,248E-03 0,01800389 ! cAMP metabolic process GO:0046058 10 10 0,000 7,248E-03 0,01797966 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 7,248E-03 0,0179555 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 7,248E-03 0,01793139 ! forelimb morphogenesis GO:0035136 10 10 0,000 7,248E-03 0,01790736 ! glial cell development GO:0021782 10 10 0,000 7,248E-03 0,01788339 ! phototransduction GO:0007602 11 10 0,000 7,248E-03 0,01785948 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 7,248E-03 0,01783563 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 7,248E-03 0,01781185 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 7,248E-03 0,01778813 ! fat cell differentiation GO:0045444 10 10 0,000 7,248E-03 0,01776448 ! myoblast differentiation GO:0045445 10 10 0,000 7,248E-03 0,01774089 ! centrosome cycle GO:0007098 10 10 0,000 7,248E-03 0,01771736 ! inactivation of MAPK activity GO:0000188 10 10 0,000 7,248E-03 0,01769389 ! positive regulation of proteolysis GO:0045862 10 10 0,000 7,248E-03 0,01767049 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 7,248E-03 0,01764715 ! regulation of survival gene product expression GO:0045884 10 10 0,000 7,248E-03 0,01762386 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 7,248E-03 0,01760064 ! epidermis morphogenesis GO:0048730 10 10 0,000 7,248E-03 0,01757749 ! protein polyubiquitination GO:0000209 10 10 0,000 7,248E-03 0,01755439 ! glutamate metabolic process GO:0006536 11 10 0,000 7,248E-03 0,01753135 ! plasma membrane organization GO:0007009 10 10 0,000 7,248E-03 0,01750837 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 7,248E-03 0,01748546 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 7,248E-03 0,0174626 ! lysosomal transport GO:0007041 10 10 0,000 7,248E-03 0,0174398 ! cellular response to unfolded protein GO:0034620 10 10 0,000 7,248E-03 0,01741706 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 7,248E-03 0,01739439 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 7,248E-03 0,01737177 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 7,248E-03 0,01734921 ! exocrine system development GO:0035272 10 10 0,000 7,248E-03 0,0173267 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 7,248E-03 0,01730426 ! neuromuscular junction development GO:0007528 10 10 0,000 7,248E-03 0,01728187 ! embryo implantation GO:0007566 11 10 0,000 7,248E-03 0,01725955 ! regulation of protein binding GO:0043393 11 10 0,000 7,248E-03 0,01723728 ! protein targeting to peroxisome GO:0006625 10 10 0,000 7,248E-03 0,01721506 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 7,248E-03 0,01719291 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 7,248E-03 0,01717081 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 7,248E-03 0,01714877 ! protein export from nucleus GO:0006611 10 10 0,000 7,248E-03 0,01712678 ! negative regulation of immune response GO:0050777 10 10 0,000 7,248E-03 0,01710485 ! cytolysis GO:0019835 10 10 0,000 7,248E-03 0,01708298 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 7,248E-03 0,01706116 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 7,248E-03 0,0170394 ! regulation of B cell differentiation GO:0045577 10 10 0,000 7,248E-03 0,01701769 ! histone deacetylation GO:0016575 10 10 0,000 7,248E-03 0,01699604 ! mRNA splice site selection GO:0006376 11 10 0,000 7,248E-03 0,01697445 ! synaptic vesicle transport GO:0048489 11 10 0,000 7,248E-03 0,0169529 ! gland morphogenesis GO:0022612 10 10 0,000 7,248E-03 0,01693142 ! positive regulation of neurological system process GO:0031646 10 10 0,000 7,248E-03 0,01690999 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 7,248E-03 0,01688861 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 7,248E-03 0,01686728 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 7,248E-03 0,01684601 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 7,248E-03 0,0168248 ! regulation of epidermis development GO:0045682 10 10 0,000 7,248E-03 0,01680363 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 7,248E-03 0,01678252 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 7,248E-03 0,01676147 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 7,248E-03 0,01674046 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 7,248E-03 0,01671951 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 7,248E-03 0,01669861 ! lymphocyte homeostasis GO:0002260 10 10 0,000 7,248E-03 0,01667776 ! nerve development GO:0021675 10 10 0,000 7,248E-03 0,01665697 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 7,248E-03 0,01663623 ! gut development GO:0048565 10 10 0,000 7,248E-03 0,01661553 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 7,248E-03 0,01659489 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 7,248E-03 0,0165743 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 7,248E-03 0,01655377 ! mRNA 3'-end processing GO:0031124 10 10 0,000 7,248E-03 0,01653328 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 7,248E-03 0,01651284 ! negative regulation of coagulation GO:0050819 11 10 0,000 7,248E-03 0,01649246 ! protein stabilization GO:0050821 10 10 0,000 7,248E-03 0,01647212 ! protein secretion GO:0009306 11 11 0,000 7,971E-03 0,01809176 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 7,971E-03 0,0180695 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 7,971E-03 0,0180473 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 7,971E-03 0,01802516 ! negative regulation of defense response GO:0031348 11 11 0,000 7,971E-03 0,01800307 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 7,971E-03 0,01798103 ! determination of bilateral symmetry GO:0009855 11 11 0,000 7,971E-03 0,01795905 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 7,971E-03 0,01793712 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 7,971E-03 0,01791525 ! skin development GO:0043588 11 11 0,000 7,971E-03 0,01789343 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 7,971E-03 0,01787166 ! signal complex assembly GO:0007172 11 11 0,000 7,971E-03 0,01784995 ! microtubule-based transport GO:0010970 11 11 0,000 7,971E-03 0,01782828 ! endothelial cell migration GO:0043542 11 11 0,000 7,971E-03 0,01780667 ! peroxisomal transport GO:0043574 11 11 0,000 7,971E-03 0,01778512 ! protein amino acid methylation GO:0006479 11 11 0,000 7,971E-03 0,01776361 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 7,971E-03 0,01774216 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 7,971E-03 0,01772075 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 7,971E-03 0,0176994 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 7,971E-03 0,01767811 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 7,971E-03 0,01765686 ! T cell proliferation GO:0042098 11 11 0,000 7,971E-03 0,01763566 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 7,971E-03 0,01761451 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 7,971E-03 0,01759342 ! regulation of viral genome replication GO:0045069 11 11 0,000 7,971E-03 0,01757237 ! spinal cord development GO:0021510 11 11 0,000 7,971E-03 0,01755138 ! activation of MAPKK activity GO:0000186 12 11 0,000 7,971E-03 0,01753044 ! smooth muscle contraction GO:0006939 11 11 0,000 7,971E-03 0,01750954 ! cellular response to starvation GO:0009267 11 11 0,000 7,971E-03 0,0174887 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 7,971E-03 0,0174679 ! digestive system process GO:0022600 11 11 0,000 7,971E-03 0,01744716 ! fucose metabolic process GO:0006004 11 11 0,000 7,971E-03 0,01742646 ! membrane budding GO:0006900 11 11 0,000 7,971E-03 0,01740581 ! apoptotic nuclear changes GO:0030262 11 11 0,000 7,971E-03 0,01738521 ! monoamine transport GO:0015844 11 11 0,000 7,971E-03 0,01736466 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 7,971E-03 0,01734416 ! response to lipopolysaccharide GO:0032496 11 11 0,000 7,971E-03 0,01732371 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 7,971E-03 0,0173033 ! body fluid secretion GO:0007589 11 11 0,000 7,971E-03 0,01728295 ! G1/S transition checkpoint GO:0031575 12 11 0,000 7,971E-03 0,01726264 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 7,971E-03 0,01724238 ! intermediate filament-based process GO:0045103 11 11 0,000 7,971E-03 0,01722216 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 7,971E-03 0,017202 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 7,971E-03 0,01718188 ! membrane depolarization GO:0051899 11 11 0,000 7,971E-03 0,01716181 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 7,971E-03 0,01714178 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 7,971E-03 0,0171218 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 7,971E-03 0,01710187 ! oogenesis GO:0048477 11 11 0,000 7,971E-03 0,01708198 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 7,971E-03 0,01706214 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 7,971E-03 0,01704235 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 7,971E-03 0,0170226 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 7,971E-03 0,0170029 ! muscle maintenance GO:0046716 12 11 0,000 7,971E-03 0,01698324 ! vitamin A metabolic process GO:0006776 11 11 0,000 7,971E-03 0,01696363 ! hindbrain development GO:0030902 11 11 0,000 7,971E-03 0,01694407 ! steroid catabolic process GO:0006706 11 11 0,000 7,971E-03 0,01692455 ! endocrine process GO:0050886 11 11 0,000 7,971E-03 0,01690507 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 7,971E-03 0,01688564 ! proximal/distal pattern formation GO:0009954 11 11 0,000 7,971E-03 0,01686625 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 7,971E-03 0,01684691 ! RNA 3'-end processing GO:0031123 11 11 0,000 7,971E-03 0,01682761 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 7,971E-03 0,01680836 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 8,693E-03 0,01831011 ! translational initiation GO:0006413 12 12 0,000 8,693E-03 0,01828921 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 8,693E-03 0,01826835 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 8,693E-03 0,01824755 ! initiation of viral infection GO:0019059 12 12 0,000 8,693E-03 0,01822679 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 8,693E-03 0,01820608 ! iron ion transport GO:0006826 13 12 0,000 8,693E-03 0,01818541 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 8,693E-03 0,01816479 ! amino sugar metabolic process GO:0006040 12 12 0,000 8,693E-03 0,01814422 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 8,693E-03 0,0181237 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 8,693E-03 0,01810322 ! heterophilic cell adhesion GO:0007157 12 12 0,000 8,693E-03 0,01808278 ! collagen metabolic process GO:0032963 12 12 0,000 8,693E-03 0,0180624 ! hindlimb morphogenesis GO:0035137 12 12 0,000 8,693E-03 0,01804206 ! xenobiotic metabolic process GO:0006805 12 12 0,000 8,693E-03 0,01802176 ! glutamate signaling pathway GO:0007215 12 12 0,000 8,693E-03 0,01800151 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 8,693E-03 0,01798131 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 8,693E-03 0,01796115 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 8,693E-03 0,01794104 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 8,693E-03 0,01792097 ! actomyosin structure organization GO:0031032 12 12 0,000 8,693E-03 0,01790095 ! microtubule organizing center organization GO:0031023 12 12 0,000 8,693E-03 0,01788097 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 8,693E-03 0,01786103 ! retinoid metabolic process GO:0001523 12 12 0,000 8,693E-03 0,01784114 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 8,693E-03 0,0178213 ! positive regulation of innate immune response GO:0045089 12 12 0,000 8,693E-03 0,0178015 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 8,693E-03 0,01778174 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 8,693E-03 0,01776202 ! acute-phase response GO:0006953 12 12 0,000 8,693E-03 0,01774235 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 8,693E-03 0,01772273 ! vacuolar transport GO:0007034 12 12 0,000 8,693E-03 0,01770315 ! polysaccharide catabolic process GO:0000272 12 12 0,000 8,693E-03 0,01768361 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 8,693E-03 0,01766411 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 8,693E-03 0,01764465 ! barbed-end actin filament capping GO:0051016 12 12 0,000 8,693E-03 0,01762524 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 8,693E-03 0,01760588 ! male gonad development GO:0008584 12 12 0,000 8,693E-03 0,01758655 ! regulation of insulin secretion GO:0050796 12 12 0,000 8,693E-03 0,01756727 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 8,693E-03 0,01754802 ! renal system process GO:0003014 12 12 0,000 8,693E-03 0,01752883 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 8,693E-03 0,01750967 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 8,693E-03 0,01749055 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 8,693E-03 0,01747148 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 8,693E-03 0,01745245 ! pallium development GO:0021543 13 12 0,000 8,693E-03 0,01743346 ! cell fate determination GO:0001709 12 12 0,000 8,693E-03 0,01741451 ! regulation of chromosome organization GO:0033044 12 12 0,000 8,693E-03 0,0173956 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 8,693E-03 0,01737673 ! somitogenesis GO:0001756 13 12 0,000 8,693E-03 0,01735791 ! G1 phase GO:0051318 13 12 0,000 8,693E-03 0,01733912 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 8,693E-03 0,01732037 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 8,693E-03 0,01730167 ! detection of light stimulus GO:0009583 13 12 0,000 8,693E-03 0,01728301 ! synaptogenesis GO:0007416 12 12 0,000 8,693E-03 0,01726438 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 8,693E-03 0,0172458 ! hormone transport GO:0009914 12 12 0,000 8,693E-03 0,01722725 ! neurotransmitter secretion GO:0007269 14 12 0,000 8,693E-03 0,01720875 ! heme biosynthetic process GO:0006783 12 12 0,000 8,693E-03 0,01719029 ! spermatid differentiation GO:0048515 13 12 0,000 8,693E-03 0,01717186 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 8,693E-03 0,01715348 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 8,693E-03 0,01713513 ! neural tube closure GO:0001843 13 12 0,000 8,693E-03 0,01711682 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 8,693E-03 0,01709856 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 8,693E-03 0,01708033 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 8,693E-03 0,01706214 ! positive regulation of DNA replication GO:0045740 14 13 0,000 9,415E-03 0,01845895 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 9,415E-03 0,01843933 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 9,415E-03 0,01841976 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 9,415E-03 0,01840023 ! phenol metabolic process GO:0018958 13 13 0,000 9,415E-03 0,01838073 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 9,415E-03 0,01836128 ! gluconeogenesis GO:0006094 13 13 0,000 9,415E-03 0,01834187 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 9,415E-03 0,01832251 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 9,415E-03 0,01830318 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 9,415E-03 0,01828389 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 9,415E-03 0,01826464 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 9,415E-03 0,01824544 ! regeneration GO:0031099 13 13 0,000 9,415E-03 0,01822627 ! keratinization GO:0031424 13 13 0,000 9,415E-03 0,01820715 ! post-embryonic development GO:0009791 14 13 0,000 9,415E-03 0,01818806 ! patterning of blood vessels GO:0001569 13 13 0,000 9,415E-03 0,01816902 ! vasculogenesis GO:0001570 13 13 0,000 9,415E-03 0,01815001 ! regulation of DNA recombination GO:0000018 13 13 0,000 9,415E-03 0,01813105 ! regulation of innate immune response GO:0045088 13 13 0,000 9,415E-03 0,01811212 ! mitochondrial membrane organization GO:0007006 13 13 0,000 9,415E-03 0,01809324 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 9,415E-03 0,01807439 ! negative regulation of DNA replication GO:0008156 13 13 0,000 9,415E-03 0,01805558 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 9,415E-03 0,01803681 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 9,415E-03 0,01801808 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 9,415E-03 0,01799939 ! autophagy GO:0006914 13 13 0,000 9,415E-03 0,01798074 ! receptor metabolic process GO:0043112 14 13 0,000 9,415E-03 0,01796212 ! actin filament bundle formation GO:0051017 13 13 0,000 9,415E-03 0,01794355 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 9,415E-03 0,01792501 ! ureteric bud development GO:0001657 13 13 0,000 9,415E-03 0,01790651 ! cell aging GO:0007569 13 13 0,000 9,415E-03 0,01788805 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 9,415E-03 0,01786963 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 9,415E-03 0,01785125 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 9,415E-03 0,0178329 ! coenzyme catabolic process GO:0009109 13 13 0,000 9,415E-03 0,01781459 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 9,415E-03 0,01779632 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 9,415E-03 0,01777809 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 9,415E-03 0,01775989 ! regulation of viral reproduction GO:0050792 13 13 0,000 9,415E-03 0,01774173 ! nucleobase metabolic process GO:0009112 13 13 0,000 9,415E-03 0,01772361 ! regulation of axonogenesis GO:0050770 14 13 0,000 9,415E-03 0,01770552 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 9,415E-03 0,01768747 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 9,415E-03 0,01766946 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 9,415E-03 0,01765149 ! vasodilation GO:0042311 14 13 0,000 9,415E-03 0,01763355 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 9,415E-03 0,01761565 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 9,415E-03 0,01759778 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 9,415E-03 0,01757995 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 9,415E-03 0,01756216 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 9,415E-03 0,0175444 ! neutrophil chemotaxis GO:0030593 14 13 0,000 9,415E-03 0,01752668 ! long-chain fatty acid transport GO:0015909 13 13 0,000 9,415E-03 0,01750899 ! immunoglobulin production GO:0002377 13 13 0,000 9,415E-03 0,01749134 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 9,415E-03 0,01747373 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 9,415E-03 0,01745615 ! cell-cell junction organization GO:0045216 13 13 0,000 9,415E-03 0,01743861 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 9,415E-03 0,0174211 ! response to cytokine stimulus GO:0034097 13 13 0,000 9,415E-03 0,01740362 ! activation of JUN kinase activity GO:0007257 13 13 0,000 9,415E-03 0,01738618 ! terpenoid metabolic process GO:0006721 13 13 0,000 9,415E-03 0,01736878 ! alkene biosynthetic process GO:0043450 13 13 0,000 9,415E-03 0,01735141 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 9,415E-03 0,01733408 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 9,415E-03 0,01731678 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 9,415E-03 0,01729951 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 9,415E-03 0,01728228 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 9,415E-03 0,01726509 ! blastocyst development GO:0001824 13 13 0,000 9,415E-03 0,01724792 ! telomere organization GO:0032200 13 13 0,000 9,415E-03 0,0172308 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 9,415E-03 0,0172137 ! regulation of amine transport GO:0051952 13 13 0,000 9,415E-03 0,01719664 ! tissue homeostasis GO:0001894 13 13 0,000 9,415E-03 0,01717962 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 9,415E-03 0,01716262 ! protein tetramerization GO:0051262 13 13 0,000 9,415E-03 0,01714566 ! neuron fate commitment GO:0048663 14 14 0,000 0,01013603 0,01844097 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01013603 0,01842278 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01013603 0,01840463 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01013603 0,01838652 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01013603 0,01836844 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01013603 0,0183504 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01013603 0,01833239 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01013603 0,01831442 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01013603 0,01829648 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01013603 0,01827858 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01013603 0,01826071 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01013603 0,01824287 ! vesicle docking GO:0048278 14 14 0,000 0,01013603 0,01822508 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01013603 0,01820731 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01013603 0,01818958 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01013603 0,01817189 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01013603 0,01815423 ! hair cycle GO:0042633 14 14 0,000 0,01013603 0,01813661 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01013603 0,01811901 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01013603 0,01810146 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01013603 0,01808393 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01013603 0,01806644 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01013603 0,01804899 ! lysosome organization GO:0007040 14 14 0,000 0,01013603 0,01803157 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01013603 0,01801418 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01013603 0,01799682 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01013603 0,0179795 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01013603 0,01796222 ! primary neural tube formation GO:0014020 15 14 0,000 0,01013603 0,01794496 ! peptide cross-linking GO:0018149 14 14 0,000 0,01013603 0,01792774 ! regulation of behavior GO:0050795 14 14 0,000 0,01013603 0,01791055 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01013603 0,01789339 ! base-excision repair GO:0006284 14 14 0,000 0,01013603 0,01787627 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01013603 0,01785918 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01013603 0,01784212 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01013603 0,0178251 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01013603 0,01780811 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01013603 0,01779115 ! collagen fibril organization GO:0030199 14 14 0,000 0,01013603 0,01777422 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01013603 0,01775732 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01013603 0,01774046 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01013603 0,01772363 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01013603 0,01770683 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01013603 0,01769006 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01013603 0,01767332 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01013603 0,01765662 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01013603 0,01763995 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01013603 0,01762331 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01085687 0,01885883 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01085687 0,01884107 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01085687 0,01882335 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01085687 0,01880566 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01085687 0,018788 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01085687 0,01877038 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01085687 0,01875278 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01085687 0,01873523 ! response to vitamin GO:0033273 15 15 0,000 0,01085687 0,0187177 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01085687 0,01870021 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01085687 0,01868275 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01085687 0,01866532 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01085687 0,01864792 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,01085687 0,01863056 ! ovarian follicle development GO:0001541 15 15 0,000 0,01085687 0,01861323 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01085687 0,01859593 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01085687 0,01857866 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01085687 0,01856143 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01085687 0,01854423 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01085687 0,01852706 ! heme metabolic process GO:0042168 15 15 0,000 0,01085687 0,01850992 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01085687 0,01849281 ! chromosome condensation GO:0030261 15 15 0,000 0,01085687 0,01847573 ! response to starvation GO:0042594 15 15 0,000 0,01085687 0,01845869 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01085687 0,01844168 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01085687 0,0184247 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01085687 0,01840775 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01085687 0,01839083 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01085687 0,01837394 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01085687 0,01835708 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01085687 0,01834026 ! phospholipid transport GO:0015914 15 15 0,000 0,01085687 0,01832346 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01085687 0,0183067 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01085687 0,01828996 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01085687 0,01827326 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01085687 0,01825659 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01085687 0,01823995 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01085687 0,01822333 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01085687 0,01820675 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01085687 0,0181902 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01085687 0,01817368 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01085687 0,01815719 ! protein homooligomerization GO:0051260 15 15 0,000 0,01085687 0,01814073 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01085687 0,01812429 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,0115773 0,01930947 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,0115773 0,01929201 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,0115773 0,01927458 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,0115773 0,01925719 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,0115773 0,01923982 ! learning GO:0007612 16 16 0,000 0,0115773 0,01922249 ! circadian rhythm GO:0007623 16 16 0,000 0,0115773 0,01920519 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,0115773 0,01918792 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,0115773 0,01917068 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,0115773 0,01915347 ! vacuole organization GO:0007033 16 16 0,000 0,0115773 0,01913629 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,0115773 0,01911914 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,0115773 0,01910203 ! vesicle targeting GO:0006903 17 16 0,000 0,0115773 0,01908494 ! segmentation GO:0035282 17 16 0,000 0,0115773 0,01906788 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,0115773 0,01905086 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,0115773 0,01903387 ! iron ion homeostasis GO:0055072 16 16 0,000 0,0115773 0,0190169 ! positive regulation of cell development GO:0010720 16 16 0,000 0,0115773 0,01899997 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,0115773 0,01898306 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,0115773 0,01896619 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,0115773 0,01894935 ! cell fate specification GO:0001708 16 16 0,000 0,0115773 0,01893253 ! pentose metabolic process GO:0019321 16 16 0,000 0,0115773 0,01891575 ! fatty acid transport GO:0015908 16 16 0,000 0,0115773 0,01889899 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,0115773 0,01888227 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,0115773 0,01886557 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,0115773 0,01884891 ! cofactor catabolic process GO:0051187 16 16 0,000 0,0115773 0,01883227 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,0115773 0,01881566 ! polyol metabolic process GO:0019751 16 16 0,000 0,0115773 0,01879909 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,0115773 0,01878254 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,0115773 0,01876602 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,0115773 0,01874953 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,0115773 0,01873307 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,0115773 0,01871663 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,0115773 0,01870023 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,0115773 0,01868386 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,0115773 0,01866751 ! regulation of coagulation GO:0050818 17 16 0,000 0,0115773 0,01865119 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0122973 0,01979383 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0122973 0,01977656 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,0122973 0,01975931 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0122973 0,0197421 ! myelination GO:0042552 17 17 0,000 0,0122973 0,01972492 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0122973 0,01970777 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0122973 0,01969064 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0122973 0,01967355 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0122973 0,01965649 ! sensory perception of smell GO:0007608 17 17 0,000 0,0122973 0,01963946 ! glucose transport GO:0015758 17 17 0,000 0,0122973 0,01962245 ! cell junction assembly GO:0034329 18 17 0,000 0,0122973 0,01960548 ! tissue remodeling GO:0048771 17 17 0,000 0,0122973 0,01958853 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0122973 0,01957162 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0122973 0,01955473 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0122973 0,01953787 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0122973 0,01952104 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0122973 0,01950424 ! neural crest cell development GO:0014032 19 17 0,000 0,0122973 0,01948747 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,0122973 0,01947073 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0122973 0,01945402 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0122973 0,01943733 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0122973 0,01942068 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0122973 0,01940405 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0122973 0,01938745 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0122973 0,01937088 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0122973 0,01935434 ! pigmentation GO:0043473 17 17 0,000 0,0122973 0,01933783 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0122973 0,01932134 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0122973 0,01930488 ! embryonic organ development GO:0048568 17 17 0,000 0,0122973 0,01928845 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0122973 0,01927205 ! liver development GO:0001889 17 17 0,000 0,0122973 0,01925568 ! gene silencing GO:0016458 17 17 0,000 0,0122973 0,01923933 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,01301689 0,02034786 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,01301689 0,02033062 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,01301689 0,0203134 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,01301689 0,02029622 ! meiosis I GO:0007127 18 18 0,000 0,01301689 0,02027906 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,01301689 0,02026193 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,01301689 0,02024483 ! membrane docking GO:0022406 18 18 0,000 0,01301689 0,02022776 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,01301689 0,02021072 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,01301689 0,02019371 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,01301689 0,02017673 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,01301689 0,02015977 ! hexose transport GO:0008645 18 18 0,000 0,01301689 0,02014284 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,01301689 0,02012595 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,01301689 0,02010908 ! striated muscle contraction GO:0006941 18 18 0,000 0,01301689 0,02009223 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,01301689 0,02007542 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,01301689 0,02005864 ! ceramide metabolic process GO:0006672 18 18 0,000 0,01301689 0,02004188 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,01301689 0,02002515 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,01301689 0,02000845 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,01301689 0,01999177 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,01301689 0,01997513 ! B cell differentiation GO:0030183 18 18 0,000 0,01301689 0,01995851 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,01301689 0,01994192 ! ensheathment of neurons GO:0007272 18 18 0,000 0,01301689 0,01992536 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,01301689 0,01990882 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,01301689 0,01989231 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,01301689 0,01987583 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,01301689 0,01985938 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,01301689 0,01984295 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01373606 0,02092194 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01373606 0,02090467 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01373606 0,02088742 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01373606 0,0208702 ! glial cell differentiation GO:0010001 19 19 0,000 0,01373606 0,02085301 ! regulation of pH GO:0006885 19 19 0,000 0,01373606 0,02083584 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01373606 0,02081871 ! feeding behavior GO:0007631 19 19 0,000 0,01373606 0,0208016 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01373606 0,02078452 ! peroxisome organization GO:0007031 19 19 0,000 0,01373606 0,02076747 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01373606 0,02075045 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01373606 0,02073346 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01373606 0,02071649 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01373606 0,02069955 ! metanephros development GO:0001656 19 19 0,000 0,01373606 0,02068264 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01373606 0,02066576 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01373606 0,0206489 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01373606 0,02063207 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01373606 0,02061527 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01373606 0,0205985 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01373606 0,02058175 ! regulation of protein stability GO:0031647 19 19 0,000 0,01373606 0,02056503 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01373606 0,02054834 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01373606 0,02053167 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,01373606 0,02051503 ! eye morphogenesis GO:0048592 19 19 0,000 0,01373606 0,02049842 ! regulation of cell shape GO:0008360 21 19 0,000 0,01373606 0,02048184 ! placenta development GO:0001890 19 19 0,000 0,01373606 0,02046528 ! response to heat GO:0009408 19 19 0,000 0,01373606 0,02044875 ! vesicle localization GO:0051648 20 19 0,000 0,01373606 0,02043224 ! regulation of muscle development GO:0048634 21 20 0,000 0,0144548 0,02148403 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0144548 0,02146672 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0144548 0,02144944 ! negative regulation of binding GO:0051100 21 20 0,000 0,0144548 0,02143218 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0144548 0,02141495 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0144548 0,02139775 ! neural tube development GO:0021915 21 20 0,000 0,0144548 0,02138058 ! nucleus organization GO:0006997 20 20 0,000 0,0144548 0,02136343 ! phagocytosis GO:0006909 21 20 0,000 0,0144548 0,02134631 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,0144548 0,02132922 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0144548 0,02131216 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0144548 0,02129512 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0144548 0,02127812 ! chromatin remodeling GO:0006338 20 20 0,000 0,0144548 0,02126113 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0144548 0,02124418 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,0144548 0,02122725 ! lipid oxidation GO:0034440 20 20 0,000 0,0144548 0,02121035 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0144548 0,02119348 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0144548 0,02117663 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0144548 0,02115981 ! RNA modification GO:0009451 20 20 0,000 0,0144548 0,02114302 ! single fertilization GO:0007338 21 20 0,000 0,0144548 0,02112625 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0144548 0,02110951 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,01517313 0,022141 ! mRNA catabolic process GO:0006402 21 21 0,000 0,01517313 0,02212348 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,01517313 0,02210599 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,01517313 0,02208853 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,01517313 0,0220711 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,01517313 0,02205369 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,01517313 0,02203631 ! Notch signaling pathway GO:0007219 22 21 0,000 0,01517313 0,02201896 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,01517313 0,02200163 ! ear morphogenesis GO:0042471 21 21 0,000 0,01517313 0,02198434 ! organic anion transport GO:0015711 21 21 0,000 0,01517313 0,02196707 ! cholesterol transport GO:0030301 21 21 0,000 0,01517313 0,02194983 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,01517313 0,02193261 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,01517313 0,02191542 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,01517313 0,02189826 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,01517313 0,02188112 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,01517313 0,02186402 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,01517313 0,02184694 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,01517313 0,02182988 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,01517313 0,02181285 ! regulation of proteolysis GO:0030162 21 21 0,000 0,01517313 0,02179585 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,01517313 0,02177888 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,01517313 0,02176193 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,01517313 0,02174501 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,01517313 0,02172811 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,01589104 0,0227385 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,01589104 0,02272086 ! sister chromatid segregation GO:0000819 22 22 0,000 0,01589104 0,02270324 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,01589104 0,02268566 ! regulation of ion transport GO:0043269 22 22 0,000 0,01589104 0,0226681 ! odontogenesis GO:0042476 22 22 0,000 0,01589104 0,02265057 ! cell junction organization GO:0034330 23 22 0,000 0,01589104 0,02263306 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,01589104 0,02261559 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,01589104 0,02259813 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,01589104 0,02258071 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,01589104 0,02256332 ! ovulation cycle process GO:0022602 22 22 0,000 0,01589104 0,02254595 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,01589104 0,0225286 ! cell chemotaxis GO:0060326 23 22 0,000 0,01589104 0,02251129 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,01589104 0,022494 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,01589104 0,02247673 ! male sex differentiation GO:0046661 22 22 0,000 0,01589104 0,0224595 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,01589104 0,02244229 ! biopolymer methylation GO:0043414 22 22 0,000 0,01589104 0,0224251 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,01589104 0,02240794 ! detection of external stimulus GO:0009581 23 22 0,000 0,01589104 0,02239081 ! neuron migration GO:0001764 22 22 0,000 0,01589104 0,02237371 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,01589104 0,02235663 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,01589104 0,02233958 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,01589104 0,02232255 ! aerobic respiration GO:0009060 22 22 0,000 0,01589104 0,02230555 ! cytokine production GO:0001816 22 22 0,000 0,01589104 0,02228857 ! cytokinesis GO:0000910 23 22 0,000 0,01589104 0,02227162 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,01589104 0,0222547 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,01660853 0,02324185 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,01660853 0,02322422 ! viral infectious cycle GO:0019058 23 23 0,000 0,01660853 0,02320661 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,01660853 0,02318903 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,01660853 0,02317147 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,01660853 0,02315395 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,01660853 0,02313644 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,01660853 0,02311897 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,01660853 0,02310152 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,01660853 0,0230841 ! endocrine system development GO:0035270 23 23 0,000 0,01660853 0,0230667 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,01660853 0,02304933 ! positive regulation of growth GO:0045927 23 23 0,000 0,01660853 0,02303199 ! female gonad development GO:0008585 23 23 0,000 0,01660853 0,02301467 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,01660853 0,02299738 ! lipid homeostasis GO:0055088 23 23 0,000 0,01660853 0,02298012 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,01660853 0,02296288 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,01660853 0,02294566 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,01660853 0,02292848 ! cell projection assembly GO:0030031 25 23 0,000 0,01660853 0,02291131 ! mitochondrial transport GO:0006839 24 24 0,000 0,0173256 0,02388263 ! regulation of action potential GO:0001508 24 24 0,000 0,0173256 0,02386478 ! gliogenesis GO:0042063 24 24 0,000 0,0173256 0,02384696 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,0173256 0,02382916 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,0173256 0,02381139 ! glucose homeostasis GO:0042593 24 24 0,000 0,0173256 0,02379365 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,0173256 0,02377593 ! T cell differentiation GO:0030217 24 24 0,000 0,0173256 0,02375824 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,0173256 0,02374058 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,0173256 0,02372294 ! ovulation cycle GO:0042698 24 24 0,000 0,0173256 0,02370533 ! fertilization GO:0009566 25 24 0,000 0,0173256 0,02368774 ! maintenance of protein location GO:0045185 25 24 0,000 0,0173256 0,02367018 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,0173256 0,02365265 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,0173256 0,02363514 ! glucan metabolic process GO:0044042 25 24 0,000 0,0173256 0,02361766 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,01804225 0,0245764 ! negative regulation of secretion GO:0051048 26 25 0,000 0,01804225 0,02455825 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,01804225 0,02454013 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,01804225 0,02452203 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,01804225 0,02450396 ! endosome transport GO:0016197 25 25 0,000 0,01804225 0,02448591 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,01804225 0,0244679 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,01804225 0,0244499 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,01804225 0,02443194 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,01804225 0,024414 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,01804225 0,02439609 ! excretion GO:0007588 25 25 0,000 0,01804225 0,0243782 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,01804225 0,02436034 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,01804225 0,02434251 ! gastrulation GO:0007369 25 25 0,000 0,01804225 0,0243247 ! heart morphogenesis GO:0003007 25 25 0,000 0,01804225 0,02430692 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,01804225 0,02428917 ! regulation of endocytosis GO:0030100 25 25 0,000 0,01804225 0,02427144 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,01804225 0,02425373 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,01804225 0,02423606 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,01804225 0,0242184 ! positive regulation of binding GO:0051099 27 26 0,000 0,01875849 0,02516149 ! positive regulation of defense response GO:0031349 26 26 0,000 0,01875849 0,02514319 ! glycolysis GO:0006096 26 26 0,000 0,01875849 0,02512492 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,01875849 0,02510667 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,01875849 0,02508845 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,01875849 0,02507026 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,01875849 0,02505209 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,01875849 0,02503395 ! cellular defense response GO:0006968 26 26 0,000 0,01875849 0,02501584 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,01875849 0,02499775 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,01875849 0,02497969 ! double-strand break repair GO:0006302 27 26 0,000 0,01875849 0,02496165 ! regulation of protein secretion GO:0050708 26 26 0,000 0,01875849 0,02494364 ! germ cell development GO:0007281 27 26 0,000 0,01875849 0,02492566 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,01875849 0,0249077 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,01875849 0,02488977 ! maintenance of location in cell GO:0051651 27 26 0,000 0,01875849 0,02487186 ! synapse organization GO:0050808 26 26 0,000 0,01875849 0,02485398 ! chloride transport GO:0006821 27 27 0,000 0,0194743 0,02578387 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,0194743 0,02576536 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,0194743 0,02574687 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,0194743 0,02572842 ! learning or memory GO:0007611 28 27 0,000 0,0194743 0,02570999 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,0194743 0,02569158 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,0194743 0,02567321 ! peptide metabolic process GO:0006518 29 27 0,000 0,0194743 0,02565485 ! activation of caspase activity GO:0006919 27 27 0,000 0,0194743 0,02563653 ! mesenchymal cell development GO:0014031 29 27 0,000 0,0194743 0,02561823 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,0194743 0,02559996 ! defense response to bacterium GO:0042742 27 27 0,000 0,0194743 0,02558171 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,0194743 0,02556349 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,0194743 0,0255453 ! cell growth GO:0016049 27 27 0,000 0,0194743 0,02552713 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,0201897 0,02644607 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0201897 0,02642729 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0201897 0,02640853 ! carbohydrate transport GO:0008643 28 28 0,000 0,0201897 0,0263898 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0201897 0,0263711 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0201897 0,02635242 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0201897 0,02633377 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,0201897 0,02631515 ! histone modification GO:0016570 28 28 0,000 0,0201897 0,02629655 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,0201897 0,02627798 ! developmental growth GO:0048589 28 28 0,000 0,0201897 0,02625944 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,0201897 0,02624092 ! cartilage development GO:0051216 29 28 0,000 0,0201897 0,02622242 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,02090468 0,02713192 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,02090468 0,02711283 ! viral reproductive process GO:0022415 29 29 0,000 0,02090468 0,02709376 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,02090468 0,02707472 ! leukocyte migration GO:0050900 30 29 0,000 0,02090468 0,02705571 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,02090468 0,02703672 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,02090468 0,02701776 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,02090468 0,02699883 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,02090468 0,02697992 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,02090468 0,02696104 ! tRNA processing GO:0008033 29 29 0,000 0,02090468 0,02694219 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,02090468 0,02692336 ! covalent chromatin modification GO:0016569 29 29 0,000 0,02090468 0,02690456 ! adult behavior GO:0030534 30 29 0,000 0,02090468 0,02688579 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,02090468 0,02686704 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,02090468 0,02684831 ! response to UV GO:0009411 29 29 0,000 0,02090468 0,02682962 ! transition metal ion transport GO:0000041 31 30 0,000 0,02161925 0,0277274 ! RNA catabolic process GO:0006401 30 30 0,000 0,02161925 0,02770812 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,02161925 0,02768886 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,02161925 0,02766963 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,02161925 0,02765043 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,02161925 0,02763126 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,02161925 0,02761211 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,02161925 0,02759299 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,02161925 0,02757389 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,02161925 0,02755482 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,02161925 0,02753578 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,02161925 0,02751676 ! response to temperature stimulus GO:0009266 30 30 0,000 0,02161925 0,02749777 ! regulation of ossification GO:0030278 30 30 0,000 0,02161925 0,02747881 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,02161925 0,02745987 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,02161925 0,02744096 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,02161925 0,02742207 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,02161925 0,02740321 ! vesicle organization GO:0016050 30 30 0,000 0,02161925 0,02738438 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,02161925 0,02736557 ! establishment of organelle localization GO:0051656 31 30 0,000 0,02161925 0,02734679 ! regulation of translational initiation GO:0006446 31 31 0,000 0,02233339 0,02823076 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,02233339 0,02821141 ! membrane fusion GO:0006944 31 31 0,000 0,02233339 0,02819209 ! B cell activation GO:0042113 31 31 0,000 0,02233339 0,02817279 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,02233339 0,02815352 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,02233339 0,02813428 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,02233339 0,02811506 ! ion transmembrane transport GO:0034220 31 31 0,000 0,02233339 0,02809587 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,02233339 0,0280767 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,02233339 0,02805756 ! digestion GO:0007586 31 31 0,000 0,02233339 0,02803845 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,02233339 0,02801936 ! regulation of DNA replication GO:0006275 32 31 0,000 0,02233339 0,0280003 ! regulation of heart contraction GO:0008016 31 31 0,000 0,02233339 0,02798127 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,02233339 0,02796226 ! camera-type eye development GO:0043010 31 31 0,000 0,02233339 0,02794328 ! extracellular matrix organization GO:0030198 31 31 0,000 0,02233339 0,02792432 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,02233339 0,02790539 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,02233339 0,02788648 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,02233339 0,0278676 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,02233339 0,02784874 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,02233339 0,02782992 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,02304712 0,0286999 ! cell redox homeostasis GO:0045454 32 32 0,000 0,02304712 0,02868052 ! muscle fiber development GO:0048747 32 32 0,000 0,02304712 0,02866117 ! glucose catabolic process GO:0006007 32 32 0,000 0,02304712 0,02864184 ! lipid modification GO:0030258 32 32 0,000 0,02304712 0,02862254 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,02304712 0,02860326 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,02304712 0,02858402 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,02304712 0,02856479 ! cell maturation GO:0048469 32 32 0,000 0,02304712 0,0285456 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,02304712 0,02852643 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,02304712 0,02850728 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,02304712 0,02848816 ! kidney development GO:0001822 32 32 0,000 0,02304712 0,02846907 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,02304712 0,02845 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,02304712 0,02843096 ! maintenance of location GO:0051235 33 32 0,000 0,02304712 0,02841194 ! negative regulation of cell size GO:0045792 33 33 0,000 0,02376044 0,02927171 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,02376044 0,02925216 ! amino acid transport GO:0006865 33 33 0,000 0,02376044 0,02923263 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,02376044 0,02921313 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,02376044 0,02919366 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,02376044 0,02917421 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,02376044 0,02915478 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,02376044 0,02913538 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,02376044 0,02911601 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,02376044 0,02909667 ! regulation of actin filament length GO:0030832 34 34 0,000 0,02447333 0,02994977 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,02447333 0,02992989 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,02447333 0,02991005 ! response to metal ion GO:0010038 34 34 0,000 0,02447333 0,02989023 ! ear development GO:0043583 34 34 0,000 0,02447333 0,02987043 ! muscle cell differentiation GO:0042692 35 34 0,000 0,02447333 0,02985066 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,02447333 0,02983092 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,02447333 0,0298112 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,02447333 0,02979151 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,02447333 0,02977185 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,02447333 0,02975221 ! secondary metabolic process GO:0019748 34 34 0,000 0,02447333 0,0297326 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,02447333 0,02971301 ! viral reproduction GO:0016032 34 34 0,000 0,02447333 0,02969345 ! detection of stimulus GO:0051606 36 34 0,000 0,02447333 0,02967391 ! acute inflammatory response GO:0002526 35 35 0,000 0,02518581 0,03051772 ! regulation of cellular component size GO:0032535 35 35 0,000 0,02518581 0,03049767 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,02518581 0,03047764 ! mesoderm development GO:0007498 35 35 0,000 0,02518581 0,03045764 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,02518581 0,03043767 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,02518581 0,03041773 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,02518581 0,03039781 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,02518581 0,03037791 ! inorganic anion transport GO:0015698 35 35 0,000 0,02518581 0,03035804 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,02518581 0,0303382 ! regulation of immune effector process GO:0002697 35 35 0,000 0,02518581 0,03031839 ! hydrogen transport GO:0006818 36 36 0,000 0,02589787 0,03115521 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,02589787 0,03113489 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,02589787 0,03111459 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,02589787 0,03109432 ! regulation of mitosis GO:0007088 37 36 0,000 0,02589787 0,03107408 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,02589787 0,03105386 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,02589787 0,03103367 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,02589787 0,0310135 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,02589787 0,03099336 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,02589787 0,03097325 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,02589787 0,03095317 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,02589787 0,03093311 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,02589787 0,03091307 ! gonad development GO:0008406 36 36 0,000 0,02589787 0,03089306 ! regulation of lipase activity GO:0060191 36 36 0,000 0,02589787 0,03087308 ! activation of immune response GO:0002253 36 36 0,000 0,02589787 0,03085312 ! coagulation GO:0050817 39 36 0,000 0,02589787 0,03083319 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,02660952 0,03166 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,02660952 0,03163958 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,02660952 0,03161918 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,02660952 0,03159881 ! response to drug GO:0042493 37 37 0,000 0,02660952 0,03157846 ! lung development GO:0030324 38 37 0,000 0,02660952 0,03155814 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,02660952 0,03153784 ! eye development GO:0001654 37 37 0,000 0,02660952 0,03151757 ! negative regulation of growth GO:0045926 37 37 0,000 0,02660952 0,03149733 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,02660952 0,03147712 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,02660952 0,03145693 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,02660952 0,03143676 ! adaptive immune response GO:0002250 37 37 0,000 0,02660952 0,03141662 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,02732075 0,03223569 ! neurotransmitter transport GO:0006836 40 38 0,000 0,02732075 0,03221506 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,02732075 0,03219447 ! exocytosis GO:0006887 40 38 0,000 0,02732075 0,03217389 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,02732075 0,03215335 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,02732075 0,03213283 ! chromosome segregation GO:0007059 38 38 0,000 0,02732075 0,03211234 ! urogenital system development GO:0001655 38 38 0,000 0,02732075 0,03209187 ! hexose catabolic process GO:0019320 38 38 0,000 0,02732075 0,03207143 ! meiotic cell cycle GO:0051321 38 38 0,000 0,02732075 0,03205102 ! axon guidance GO:0007411 39 38 0,000 0,02732075 0,03203063 ! regulation of neurological system process GO:0031644 38 38 0,000 0,02732075 0,03201026 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,02732075 0,03198993 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,02803157 0,03280138 ! hemostasis GO:0007599 42 39 0,000 0,02803157 0,03278057 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,02803157 0,03275978 ! activation of MAPK activity GO:0000187 39 39 0,000 0,02803157 0,03273902 ! respiratory tube development GO:0030323 40 39 0,000 0,02803157 0,03271829 ! response to unfolded protein GO:0006986 39 39 0,000 0,02803157 0,03269758 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,02803157 0,0326769 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,02803157 0,03265624 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,02803157 0,03263561 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,02803157 0,03261501 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,02803157 0,03259443 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,02803157 0,03257388 ! respiratory system development GO:0060541 40 39 0,000 0,02803157 0,03255336 ! developmental maturation GO:0021700 39 39 0,000 0,02803157 0,03253286 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,02803157 0,03251238 ! limb development GO:0060173 39 39 0,000 0,02803157 0,03249194 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,02803157 0,03247151 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,02803157 0,03245112 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,02874197 0,03325263 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,02874197 0,03323177 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,02874197 0,03321094 ! organelle localization GO:0051640 41 40 0,000 0,02874197 0,03319013 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,02945195 0,03398869 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,02945195 0,03396742 ! amine catabolic process GO:0009310 42 41 0,000 0,02945195 0,03394618 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,02945195 0,03392496 ! regulation of caspase activity GO:0043281 41 41 0,000 0,02945195 0,03390377 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,02945195 0,03388261 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,02945195 0,03386147 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,02945195 0,03384036 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,03016152 0,03463407 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,03016152 0,0346125 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,03016152 0,03459096 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,03016152 0,03456945 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,03016152 0,03454797 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,03016152 0,03452651 ! protein ubiquitination GO:0016567 43 42 0,000 0,03016152 0,03450508 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,03016152 0,03448367 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,03016152 0,03446229 ! forebrain development GO:0030900 43 42 0,000 0,03016152 0,03444094 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,03016152 0,03441962 ! reproductive structure development GO:0048608 43 43 0,000 0,03087067 0,03520708 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,03087067 0,03518531 ! mitochondrion organization GO:0007005 44 43 0,000 0,03087067 0,03516357 ! alcohol catabolic process GO:0046164 43 43 0,000 0,03087067 0,03514185 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,03087067 0,03512015 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,03087067 0,03509849 ! humoral immune response GO:0006959 44 44 0,000 0,03157941 0,03588215 ! mRNA transport GO:0051028 44 44 0,000 0,03157941 0,03586005 ! protein import into nucleus GO:0006606 44 44 0,000 0,03157941 0,03583796 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,03157941 0,03581591 ! vitamin metabolic process GO:0006766 44 44 0,000 0,03157941 0,03579388 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,03157941 0,03577188 ! amine biosynthetic process GO:0009309 46 45 0,000 0,03228773 0,03655178 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,03228773 0,03652934 ! regulation of DNA binding GO:0051101 47 45 0,000 0,03228773 0,03650693 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,03228773 0,03648455 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,03228773 0,03646219 ! nuclear import GO:0051170 45 45 0,000 0,03228773 0,03643986 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,03228773 0,03641756 ! protein processing GO:0016485 45 45 0,000 0,03228773 0,03639529 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,03299564 0,03717052 ! tube morphogenesis GO:0035239 47 46 0,000 0,03299564 0,03714781 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,03299564 0,03712514 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,03299564 0,03710248 ! regulation of membrane potential GO:0042391 46 46 0,000 0,03299564 0,03707986 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,03370314 0,03785185 ! regulation of blood pressure GO:0008217 48 47 0,000 0,03370314 0,0378288 ! sex differentiation GO:0007548 47 47 0,000 0,03370314 0,03780577 ! amine transport GO:0015837 47 47 0,000 0,03370314 0,03778278 ! rhythmic process GO:0048511 47 47 0,000 0,03370314 0,03775981 ! regulation of catabolic process GO:0009894 48 47 0,000 0,03370314 0,03773687 ! calcium ion transport GO:0006816 48 48 0,000 0,03441022 0,03850518 ! actin filament organization GO:0007015 50 48 0,000 0,03441022 0,03848182 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,03441022 0,03845848 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,03441022 0,03843517 ! protein localization in nucleus GO:0034504 48 48 0,000 0,03441022 0,03841189 ! DNA recombination GO:0006310 48 48 0,000 0,03441022 0,03838864 ! leukocyte differentiation GO:0002521 50 49 0,000 0,03511689 0,03915331 ! ossification GO:0001503 50 49 0,000 0,03511689 0,03912964 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,03511689 0,039106 ! cell cycle arrest GO:0007050 49 49 0,000 0,03511689 0,03908238 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,03511689 0,03905879 ! divalent metal ion transport GO:0070838 49 49 0,000 0,03511689 0,03903524 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,03511689 0,03901171 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,03511689 0,03898821 ! response to bacterium GO:0009617 50 49 0,000 0,03511689 0,03896473 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,03511689 0,03894129 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,03511689 0,03891787 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,03511689 0,03889449 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,03582314 0,03965288 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,03582314 0,03962908 ! negative regulation of transport GO:0051051 51 50 0,000 0,03582314 0,03960531 ! chromatin assembly GO:0031497 50 50 0,000 0,03582314 0,03958156 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,03582314 0,03955785 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,03582314 0,03953416 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,03582314 0,0395105 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,03582314 0,03948687 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,03582314 0,03946327 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,03582314 0,03943969 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,03652898 0,04019278 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,03652898 0,0401688 ! positive regulation of immune response GO:0050778 51 51 0,000 0,03652898 0,04014485 ! rRNA metabolic process GO:0016072 51 51 0,000 0,03652898 0,04012092 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,03652898 0,04009703 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,03652898 0,04007316 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,03652898 0,04004932 ! protein maturation GO:0051604 51 51 0,000 0,03652898 0,04002551 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,03723441 0,04077422 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,03723441 0,04075001 ! cell fate commitment GO:0045165 52 52 0,000 0,03723441 0,04072582 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,03723441 0,04070167 ! response to light stimulus GO:0009416 53 52 0,000 0,03723441 0,04067754 ! sodium ion transport GO:0006814 53 53 0,000 0,03793942 0,04142319 ! tRNA metabolic process GO:0006399 53 53 0,000 0,03793942 0,04139867 ! response to hypoxia GO:0001666 53 53 0,000 0,03793942 0,04137417 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,03793942 0,0413497 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,03793942 0,04132527 ! regulation of T cell activation GO:0050863 53 53 0,000 0,03793942 0,04130086 ! regulation of protein transport GO:0051223 53 53 0,000 0,03793942 0,04127648 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,03864402 0,04201825 ! response to oxygen levels GO:0070482 55 54 0,000 0,03864402 0,04199347 ! response to virus GO:0009615 54 54 0,000 0,03864402 0,04196873 ! hormone metabolic process GO:0042445 55 54 0,000 0,03864402 0,04194401 ! sulfur metabolic process GO:0006790 55 54 0,000 0,03864402 0,04191932 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,03864402 0,04189466 ! nucleosome organization GO:0034728 55 55 0,000 0,03934821 0,04263301 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,03934821 0,04260796 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,03934821 0,04258294 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,03934821 0,04255795 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,04005198 0,04329372 ! reproductive developmental process GO:0003006 56 56 0,000 0,04005198 0,04326835 ! extracellular structure organization GO:0043062 56 56 0,000 0,04005198 0,043243 ! regulation of nervous system development GO:0051960 57 56 0,000 0,04005198 0,04321768 ! regulation of binding GO:0051098 60 57 0,000 0,04075534 0,0439509 ! ATP metabolic process GO:0046034 57 57 0,000 0,04075534 0,0439252 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,04075534 0,04389953 ! regulation of protein localization GO:0032880 58 57 0,000 0,04075534 0,04387389 ! innate immune response GO:0045087 58 58 0,000 0,04145829 0,04460457 ! dephosphorylation GO:0016311 60 59 0,000 0,04216083 0,04533396 ! carboxylic acid transport GO:0046942 59 59 0,000 0,04216083 0,04530753 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,04216083 0,04528112 ! regulation of cell development GO:0060284 60 59 0,000 0,04216083 0,04525475 ! sterol metabolic process GO:0016125 59 59 0,000 0,04216083 0,04522841 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,04216083 0,0452021 ! protein localization in organelle GO:0033365 59 59 0,000 0,04216083 0,04517582 ! immune effector process GO:0002252 59 59 0,000 0,04216083 0,04514957 ! potassium ion transport GO:0006813 60 60 0,000 0,04286295 0,04587481 ! protein polymerization GO:0051258 65 60 0,000 0,04286295 0,04584819 ! cellular respiration GO:0045333 62 61 0,000 0,04356467 0,04657174 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,04356467 0,04654474 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,04356467 0,04651778 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,04356467 0,04649084 ! lipid transport GO:0006869 62 62 0,000 0,04426597 0,04721191 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,04426597 0,0471846 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,04426597 0,04715733 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,04426597 0,04713009 ! protein import GO:0017038 62 62 0,000 0,04426597 0,04710288 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,04426597 0,0470757 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,04426597 0,04704855 ! regulation of secretion GO:0051046 65 63 0,000 0,04496686 0,04776595 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,04496686 0,04773843 ! glucose metabolic process GO:0006006 63 63 0,000 0,04496686 0,04771095 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,04496686 0,0476835 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,04496686 0,04765608 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,04566734 0,04837063 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,04566734 0,04834285 ! angiogenesis GO:0001525 65 64 0,000 0,04566734 0,0483151 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,04566734 0,04828738 ! anion transport GO:0006820 65 65 0,000 0,04636741 0,0489995 ! regulation of hormone levels GO:0010817 66 65 0,000 0,04636741 0,04897142 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,04706706 0,0496819 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,04706706 0,04965346 ! DNA packaging GO:0006323 66 66 0,000 0,04706706 0,04962506 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,04706706 0,04959668 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,04706706 0,04956834 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,04776631 0,05027602 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,04776631 0,05024732 ! muscle contraction GO:0006936 67 67 0,000 0,04776631 0,05021866 ! striated muscle tissue development GO:0014706 69 67 0,000 0,04776631 0,05019003 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,04776631 0,05016143 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,04776631 0,05013286 ! response to radiation GO:0009314 70 68 0,000 0,04846515 0,05083737 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,04846515 0,05080845 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,04846515 0,05077957 ! regulation of cell size GO:0008361 68 68 0,000 0,04846515 0,05075072 ! sensory perception of sound GO:0007605 71 69 0,000 0,04916357 0,05145285 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,04916357 0,05142364 ! response to nutrient levels GO:0031667 69 69 0,000 0,04916357 0,05139448 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,04916357 0,05136534 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,04916357 0,05133624 ! positive regulation of transport GO:0051050 71 70 0,000 0,04986159 0,05203562 ! cell part morphogenesis GO:0032990 75 70 0,000 0,04986159 0,05200617 ! wound healing GO:0042060 74 70 0,000 0,04986159 0,05197675 ! growth GO:0040007 70 70 0,000 0,04986159 0,05194737 ! muscle tissue development GO:0060537 72 70 0,000 0,04986159 0,05191802 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,04986159 0,05188871 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,05055919 0,05258498 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,05055919 0,05255532 ! regulation of cell migration GO:0030334 71 71 0,000 0,05055919 0,0525257 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,05055919 0,05249611 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 0,000 0,05055919 0,05246655 ! secretion by cell GO:0032940 75 72 0,000 0,05125639 0,05316011 ! muscle system process GO:0003012 72 72 0,000 0,05125639 0,05313021 ! sensory organ development GO:0007423 72 72 0,000 0,05125639 0,05310035 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,05125639 0,05307052 ! regulation of cytokine production GO:0001817 72 72 0,000 0,05125639 0,05304072 ! electron transport chain GO:0022900 75 74 0,000 0,05264955 0,05445181 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,05264955 0,05442127 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,05334552 0,05510975 ! response to oxidative stress GO:0006979 76 75 0,000 0,05334552 0,05507887 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,05334552 0,05504803 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,05404107 0,05573458 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,05473622 0,05641994 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,05473622 0,05638841 ! microtubule-based movement GO:0007018 82 78 0,000 0,05543096 0,05707222 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,05543096 0,05704035 ! metal ion homeostasis GO:0055065 78 78 0,000 0,05543096 0,05700852 ! regulation of immune response GO:0050776 78 78 0,000 0,05543096 0,05697672 ! regulation of locomotion GO:0040012 79 79 0,000 0,0561253 0,05765826 ! regulation of cell motion GO:0051270 79 79 0,000 0,0561253 0,05762614 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,05681922 0,05830614 ! neuron projection development GO:0031175 85 80 0,000 0,05681922 0,05827369 ! MAPKKK cascade GO:0000165 82 81 0,000 0,05751273 0,05895215 ! tube development GO:0035295 83 81 0,000 0,05751273 0,05891938 ! lymphocyte activation GO:0046649 82 81 0,000 0,05751273 0,05888665 ! lipid catabolic process GO:0016042 82 81 0,000 0,05751273 0,05885395 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,05889854 0,06023863 ! ncRNA processing GO:0034470 83 83 0,000 0,05889854 0,06020522 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,05889854 0,06017185 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,05959083 0,06084538 ! regulation of cellular localization GO:0060341 86 85 0,000 0,06028272 0,06151774 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,06028272 0,0614837 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,06028272 0,06144969 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,06028272 0,06141573 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,06097419 0,06208588 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,06097419 0,0620516 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,06097419 0,06201735 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,06097419 0,06198314 ! heart development GO:0007507 90 87 0,000 0,06166526 0,06265109 ! male gamete generation GO:0048232 90 88 0,000 0,06235593 0,06331789 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,06235593 0,06328302 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,06235593 0,0632482 ! chemotaxis GO:0006935 90 89 0,000 0,06304618 0,06391315 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,06304618 0,06387802 ! brain development GO:0007420 91 90 0,000 0,06373603 0,06454149 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,06442548 0,06520382 ! DNA replication GO:0006260 91 91 0,000 0,06442548 0,06516803 ! visual perception GO:0007601 93 92 0,000 0,06511451 0,06582888 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,06511451 0,06579279 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,06511451 0,06575674 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,06511451 0,06572073 ! tissue morphogenesis GO:0048729 94 93 0,000 0,06580314 0,06637942 ! regulation of response to stress GO:0080134 97 94 0,000 0,06649137 0,06703698 ! blood vessel development GO:0001568 95 94 0,000 0,06649137 0,06700032 ! pattern specification process GO:0007389 96 94 0,000 0,06649137 0,06696371 ! epidermis development GO:0008544 94 94 0,000 0,06649137 0,06692714 ! cofactor metabolic process GO:0051186 95 94 0,000 0,06649137 0,06689061 ! regulation of cell growth GO:0001558 97 96 0,000 0,0678666 0,06823685 ! vasculature development GO:0001944 97 96 0,000 0,0678666 0,06819965 ! endocytosis GO:0006897 99 98 0,000 0,06924022 0,06954208 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,06924022 0,0695042 ! blood circulation GO:0008015 99 98 0,000 0,06924022 0,06946637 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,06924022 0,06942857 ! ectoderm development GO:0007398 99 99 0,000 0,06992641 0,07007851 ! muscle organ development GO:0007517 102 100 0,000 0,07061221 0,07072734 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,07061221 0,07068892 ! response to other organism GO:0051707 101 100 0,000 0,07061221 0,07065054 ! hemopoiesis GO:0030097 104 100 0,000 0,07061221 0,07061221