Study run-a1

Study informations

119 subnetworks in total page | file

406 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6241-7-real

score

Dataset	Score	P-val 1	P-val 2	P-val 3
Desmedt	0.1893	5.017e-03	5.963e-03	5.847e-02
IPC-NIBC-129	0.2221	6.387e-02	8.248e-02	5.280e-01
Ivshina_GPL96-GPL97	0.2816	1.350e-02	2.016e-02	3.137e-01
Loi_GPL570	0.2289	8.963e-02	8.908e-02	3.846e-01
Loi_GPL96-GPL97	0.1996	2.220e-04	9.960e-04	6.145e-03
Parker_GPL1390	0.2404	1.140e-01	1.149e-01	5.754e-01
Parker_GPL887	0.0903	6.847e-01	7.111e-01	7.392e-01
Pawitan_GPL96-GPL97	0.3702	1.795e-01	1.441e-01	7.095e-01
Schmidt	0.1939	9.775e-03	1.398e-02	1.285e-01
Sotiriou	0.3166	2.326e-03	6.600e-04	5.915e-02
Wang	0.1979	5.824e-02	3.657e-02	2.536e-01
Zhang	0.2134	8.092e-02	5.083e-02	1.988e-01
Zhou	0.4172	5.563e-02	5.829e-02	3.486e-01

Expression data for subnetwork 6241-7-real in each dataset

Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Wang | Zhang | Zhou |

Subnetwork structure for each dataset

Desmedt IPC-NIBC-129 Ivshina_GPL96-GPL97 Loi_GPL570 Loi_GPL96-GPL97 Parker_GPL1390 Parker_GPL887 Pawitan_GPL96-GPL97 Schmidt Sotiriou Wang Zhang Zhou

Desmedt

Score for each gene in subnetwork 6241-7-real in each dataset

Gene Symbol	Links	Frequency	Frequency Rank	Subnetwork score rank	Global rank	Desmedt	IPC-NIBC-129	Ivshina_GPL96-GPL97	Loi_GPL570	Loi_GPL96-GPL97	Parker_GPL1390	Parker_GPL887	Pawitan_GPL96-GPL97	Schmidt	Sotiriou	Wang	Zhang	Zhou
ccnb2		16	13	153	125	0.164	0.176	0.204	0.123	0.172	0.178	0.090	0.366	0.240	0.169	0.144	0.211	0.463
cdc2		103	1	1	1	0.073	0.247	0.206	0.172	0.247	0.153	-0.131	0.282	0.226	0.221	0.067	0.297	0.336
rrm2		21	10	44	26	0.131	0.207	0.227	0.187	0.161	0.178	0.137	0.303	0.190	0.219	0.117	0.129	0.302
cdkn1a		70	3	73	51	0.115	-0.020	0.065	0.082	0.099	0.124	0.055	0.087	0.068	0.144	0.015	-0.201	0.069
sfn		50	4	29	17	0.077	0.137	0.111	0.172	0.112	0.119	0.141	0.219	0.100	0.147	0.025	0.079	0.181
ccnb1		36	7	78	59	0.082	0.246	0.212	0.224	0.256	0.099	0.126	0.351	0.129	0.249	0.152	0.167	0.398
clec11a		17	12	44	27	0.013	0.101	0.071	-0.085	0.066	0.082	0.209	-0.126	-0.034	-0.001	0.191	0.059	-0.075
ccnd1		102	2	1	2	0.127	-0.183	0.062	0.190	0.157	-0.002	-0.190	0.105	-0.107	0.174	0.106	0.144	0.290

GO Enrichment output for subnetwork 6241-7-real in each dataset

Desmedt file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		8.165E-09	1.878E-05
nucleoside diphosphate metabolic process	GO:0009132		1.428E-08	1.642E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.293E-08	4.824E-05
interphase of mitotic cell cycle	GO:0051329		5.262E-07	3.026E-04
G2/M transition of mitotic cell cycle	GO:0000086		5.392E-07	2.48E-04
deoxyribonucleotide metabolic process	GO:0009262		5.392E-07	2.067E-04
interphase	GO:0051325		5.773E-07	1.897E-04
induction of apoptosis by intracellular signals	GO:0008629		3.969E-06	1.141E-03
G1/S transition of mitotic cell cycle	GO:0000082		4.951E-06	1.265E-03
response to UV	GO:0009411		6.081E-06	1.399E-03
negative regulation of protein kinase activity	GO:0006469		1.166E-05	2.438E-03

IPC-NIBC-129 file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of cyclin-dependent protein kinase activity	GO:0000079		8.003E-09	1.955E-05
interphase of mitotic cell cycle	GO:0051329		7.245E-08	8.849E-05
G2/M transition of mitotic cell cycle	GO:0000086		1.391E-07	1.132E-04
induction of apoptosis by intracellular signals	GO:0008629		8.536E-07	5.213E-04
G1/S transition of mitotic cell cycle	GO:0000082		9.129E-07	4.461E-04
response to UV	GO:0009411		1.574E-06	6.41E-04
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	GO:0031145		2.997E-06	1.046E-03
negative regulation of protein kinase activity	GO:0006469		3.133E-06	9.567E-04
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	GO:0051437		3.133E-06	8.504E-04
negative regulation of kinase activity	GO:0033673		3.272E-06	7.994E-04
deoxyribonucleotide biosynthetic process	GO:0009263		3.486E-06	7.743E-04

Ivshina_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		3.494E-09	8.406E-06
nucleoside diphosphate metabolic process	GO:0009132		8.381E-09	1.008E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.549E-08	1.242E-05
interphase of mitotic cell cycle	GO:0051329		1.235E-07	7.426E-05
interphase	GO:0051325		1.4E-07	6.735E-05
deoxyribonucleotide metabolic process	GO:0009262		1.53E-07	6.137E-05
G2/M transition of mitotic cell cycle	GO:0000086		2.284E-07	7.849E-05
induction of apoptosis by intracellular signals	GO:0008629		1.401E-06	4.212E-04
G1/S transition of mitotic cell cycle	GO:0000082		1.498E-06	4.004E-04
response to UV	GO:0009411		2.307E-06	5.55E-04
negative regulation of protein kinase activity	GO:0006469		4.697E-06	1.027E-03

Loi_GPL570 file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of cyclin-dependent protein kinase activity	GO:0000079		8.003E-09	1.955E-05
interphase of mitotic cell cycle	GO:0051329		7.245E-08	8.849E-05
G2/M transition of mitotic cell cycle	GO:0000086		1.391E-07	1.132E-04
induction of apoptosis by intracellular signals	GO:0008629		8.536E-07	5.213E-04
G1/S transition of mitotic cell cycle	GO:0000082		9.129E-07	4.461E-04
response to UV	GO:0009411		1.574E-06	6.41E-04
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	GO:0031145		2.997E-06	1.046E-03
negative regulation of protein kinase activity	GO:0006469		3.133E-06	9.567E-04
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	GO:0051437		3.133E-06	8.504E-04
negative regulation of kinase activity	GO:0033673		3.272E-06	7.994E-04
deoxyribonucleotide biosynthetic process	GO:0009263		3.486E-06	7.743E-04

Loi_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		3.494E-09	8.406E-06
nucleoside diphosphate metabolic process	GO:0009132		8.381E-09	1.008E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.549E-08	1.242E-05
interphase of mitotic cell cycle	GO:0051329		1.235E-07	7.426E-05
interphase	GO:0051325		1.4E-07	6.735E-05
deoxyribonucleotide metabolic process	GO:0009262		1.53E-07	6.137E-05
G2/M transition of mitotic cell cycle	GO:0000086		2.284E-07	7.849E-05
induction of apoptosis by intracellular signals	GO:0008629		1.401E-06	4.212E-04
G1/S transition of mitotic cell cycle	GO:0000082		1.498E-06	4.004E-04
response to UV	GO:0009411		2.307E-06	5.55E-04
negative regulation of protein kinase activity	GO:0006469		4.697E-06	1.027E-03

Parker_GPL1390 file

Name	Accession Number	Link	P-val	Corrected P-val
cyclin-dependent protein kinase holoenzyme complex	GO:0000307		3.674E-09	1.312E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		4.076E-09	7.277E-06
cyclin-dependent protein kinase regulator activity	GO:0016538		1.082E-08	1.288E-05
protein kinase regulator activity	GO:0019887		1.122E-08	1.002E-05
kinase regulator activity	GO:0019207		2.384E-08	1.703E-05
protein serine/threonine kinase inhibitor activity	GO:0030291		2.385E-08	1.419E-05
interphase of mitotic cell cycle	GO:0051329		3.079E-08	1.571E-05
G2/M transition of mitotic cell cycle	GO:0000086		4.453E-08	1.988E-05
protein kinase inhibitor activity	GO:0004860		2.14E-07	8.492E-05
kinase inhibitor activity	GO:0019210		2.651E-07	9.468E-05
induction of apoptosis by intracellular signals	GO:0008629		8.038E-07	2.609E-04

Parker_GPL887 file

Name	Accession Number	Link	P-val	Corrected P-val
cyclin-dependent protein kinase holoenzyme complex	GO:0000307		2.866E-09	1.045E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		3.392E-09	6.188E-06
protein kinase regulator activity	GO:0019887		9.758E-09	1.187E-05
kinase regulator activity	GO:0019207		1.734E-08	1.582E-05
cyclin-dependent protein kinase regulator activity	GO:0016538		1.861E-08	1.357E-05
interphase of mitotic cell cycle	GO:0051329		2.247E-08	1.366E-05
interphase	GO:0051325		2.481E-08	1.293E-05
protein serine/threonine kinase inhibitor activity	GO:0030291		2.861E-08	1.305E-05
G2/M transition of mitotic cell cycle	GO:0000086		2.861E-08	1.16E-05
protein kinase inhibitor activity	GO:0004860		3.046E-07	1.111E-04
kinase inhibitor activity	GO:0019210		3.331E-07	1.105E-04

Pawitan_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		3.494E-09	8.406E-06
nucleoside diphosphate metabolic process	GO:0009132		8.381E-09	1.008E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.549E-08	1.242E-05
interphase of mitotic cell cycle	GO:0051329		1.235E-07	7.426E-05
interphase	GO:0051325		1.4E-07	6.735E-05
deoxyribonucleotide metabolic process	GO:0009262		1.53E-07	6.137E-05
G2/M transition of mitotic cell cycle	GO:0000086		2.284E-07	7.849E-05
induction of apoptosis by intracellular signals	GO:0008629		1.401E-06	4.212E-04
G1/S transition of mitotic cell cycle	GO:0000082		1.498E-06	4.004E-04
response to UV	GO:0009411		2.307E-06	5.55E-04
negative regulation of protein kinase activity	GO:0006469		4.697E-06	1.027E-03

Schmidt file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		8.165E-09	1.878E-05
nucleoside diphosphate metabolic process	GO:0009132		1.428E-08	1.642E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.293E-08	4.824E-05
interphase of mitotic cell cycle	GO:0051329		5.262E-07	3.026E-04
G2/M transition of mitotic cell cycle	GO:0000086		5.392E-07	2.48E-04
deoxyribonucleotide metabolic process	GO:0009262		5.392E-07	2.067E-04
interphase	GO:0051325		5.773E-07	1.897E-04
induction of apoptosis by intracellular signals	GO:0008629		3.969E-06	1.141E-03
G1/S transition of mitotic cell cycle	GO:0000082		4.951E-06	1.265E-03
response to UV	GO:0009411		6.081E-06	1.399E-03
negative regulation of protein kinase activity	GO:0006469		1.166E-05	2.438E-03

Sotiriou file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		8.165E-09	1.878E-05
nucleoside diphosphate metabolic process	GO:0009132		1.428E-08	1.642E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.293E-08	4.824E-05
interphase of mitotic cell cycle	GO:0051329		5.262E-07	3.026E-04
G2/M transition of mitotic cell cycle	GO:0000086		5.392E-07	2.48E-04
deoxyribonucleotide metabolic process	GO:0009262		5.392E-07	2.067E-04
interphase	GO:0051325		5.773E-07	1.897E-04
induction of apoptosis by intracellular signals	GO:0008629		3.969E-06	1.141E-03
G1/S transition of mitotic cell cycle	GO:0000082		4.951E-06	1.265E-03
response to UV	GO:0009411		6.081E-06	1.399E-03
negative regulation of protein kinase activity	GO:0006469		1.166E-05	2.438E-03

Wang file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		8.165E-09	1.878E-05
nucleoside diphosphate metabolic process	GO:0009132		1.428E-08	1.642E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.293E-08	4.824E-05
interphase of mitotic cell cycle	GO:0051329		5.262E-07	3.026E-04
G2/M transition of mitotic cell cycle	GO:0000086		5.392E-07	2.48E-04
deoxyribonucleotide metabolic process	GO:0009262		5.392E-07	2.067E-04
interphase	GO:0051325		5.773E-07	1.897E-04
induction of apoptosis by intracellular signals	GO:0008629		3.969E-06	1.141E-03
G1/S transition of mitotic cell cycle	GO:0000082		4.951E-06	1.265E-03
response to UV	GO:0009411		6.081E-06	1.399E-03
negative regulation of protein kinase activity	GO:0006469		1.166E-05	2.438E-03

Zhang file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		8.165E-09	1.878E-05
nucleoside diphosphate metabolic process	GO:0009132		1.428E-08	1.642E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.293E-08	4.824E-05
interphase of mitotic cell cycle	GO:0051329		5.262E-07	3.026E-04
G2/M transition of mitotic cell cycle	GO:0000086		5.392E-07	2.48E-04
deoxyribonucleotide metabolic process	GO:0009262		5.392E-07	2.067E-04
interphase	GO:0051325		5.773E-07	1.897E-04
induction of apoptosis by intracellular signals	GO:0008629		3.969E-06	1.141E-03
G1/S transition of mitotic cell cycle	GO:0000082		4.951E-06	1.265E-03
response to UV	GO:0009411		6.081E-06	1.399E-03
negative regulation of protein kinase activity	GO:0006469		1.166E-05	2.438E-03

Zhou file

Name	Accession Number	Link	P-val	Corrected P-val
deoxyribonucleotide biosynthetic process	GO:0009263		1.492E-08	3.541E-05
nucleoside diphosphate metabolic process	GO:0009132		2.386E-08	2.832E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		7.987E-08	6.318E-05
G2/M transition of mitotic cell cycle	GO:0000086		5.632E-07	3.341E-04
interphase of mitotic cell cycle	GO:0051329		5.972E-07	2.834E-04
deoxyribonucleotide metabolic process	GO:0009262		6.518E-07	2.578E-04
interphase	GO:0051325		6.545E-07	2.219E-04
induction of apoptosis by intracellular signals	GO:0008629		4.811E-06	1.427E-03
G1/S transition of mitotic cell cycle	GO:0000082		5.545E-06	1.462E-03
response to UV	GO:0009411		6.779E-06	1.609E-03
positive regulation of cyclin-dependent protein kinase activity	GO:0045737		1.271E-05	2.743E-03