Study run-a1
Study informations
119 subnetworks in total page | file
406 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 5518-6-real
score
Dataset | Score | P-val 1 | P-val 2 | P-val 3 |
Desmedt | 0.1554 | 6.311e-03 | 7.517e-03 | 6.985e-02 |
IPC-NIBC-129 | 0.2894 | 7.061e-02 | 9.166e-02 | 5.602e-01 |
Ivshina_GPL96-GPL97 | 0.2706 | 3.697e-03 | 6.292e-03 | 1.394e-01 |
Loi_GPL570 | 0.2893 | 3.574e-02 | 3.545e-02 | 1.978e-01 |
Loi_GPL96-GPL97 | 0.1502 | 8.100e-05 | 4.120e-04 | 1.607e-03 |
Parker_GPL1390 | 0.2330 | 1.811e-01 | 1.890e-01 | 7.024e-01 |
Parker_GPL887 | 0.0125 | 9.745e-01 | 9.776e-01 | 9.900e-01 |
Pawitan_GPL96-GPL97 | 0.3737 | 1.723e-01 | 1.373e-01 | 6.960e-01 |
Schmidt | 0.2088 | 1.547e-02 | 2.168e-02 | 1.818e-01 |
Sotiriou | 0.2885 | 4.400e-04 | 8.000e-05 | 1.684e-02 |
Wang | 0.1611 | 1.295e-01 | 9.302e-02 | 4.311e-01 |
Zhang | 0.2175 | 1.370e-01 | 9.546e-02 | 3.157e-01 |
Zhou | 0.5165 | 5.379e-02 | 5.617e-02 | 3.385e-01 |
Expression data for subnetwork 5518-6-real in each dataset
Desmedt |
IPC-NIBC-129 |
Ivshina_GPL96-GPL97 |
Loi_GPL570 |
Loi_GPL96-GPL97 |
Parker_GPL1390 |
Parker_GPL887 |
Pawitan_GPL96-GPL97 |
Schmidt |
Sotiriou |
Wang |
Zhang |
Zhou |
Subnetwork structure for each dataset
- Desmedt

Score for each gene in subnetwork 5518-6-real in each dataset
Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Wang | Zhang | Zhou |
tsc1 |  | 47 | 5 | 17 | 8 | 0.049 | 0.012 | -0.055 | 0.072 | 0.055 | -0.144 | -0.242 | -0.196 | 0.006 | 0.010 | 0.043 | -0.007 | 0.207 |
map4 |  | 16 | 13 | 73 | 55 | 0.002 | 0.046 | 0.067 | -0.043 | 0.034 | 0.119 | 0.159 | -0.058 | -0.020 | 0.043 | 0.108 | -0.074 | 0.302 |
cdc2 |  | 103 | 1 | 1 | 1 | 0.073 | 0.247 | 0.206 | 0.172 | 0.247 | 0.153 | -0.131 | 0.282 | 0.226 | 0.221 | 0.067 | 0.297 | 0.336 |
sfn |  | 50 | 4 | 29 | 17 | 0.077 | 0.137 | 0.111 | 0.172 | 0.112 | 0.119 | 0.141 | 0.219 | 0.100 | 0.147 | 0.025 | 0.079 | 0.181 |
eif2s1 |  | 14 | 17 | 73 | 57 | -0.031 | 0.151 | 0.253 | 0.182 | 0.098 | 0.167 | 0.005 | 0.270 | 0.233 | 0.038 | 0.122 | 0.239 | 0.265 |
ppp2r1a |  | 2 | 104 | 130 | 131 | 0.129 | 0.059 | 0.161 | 0.011 | 0.112 | 0.220 | -0.282 | 0.078 | -0.109 | 0.129 | -0.121 | -0.134 | 0.300 |
ccnb1 |  | 36 | 7 | 78 | 59 | 0.082 | 0.246 | 0.212 | 0.224 | 0.256 | 0.099 | 0.126 | 0.351 | 0.129 | 0.249 | 0.152 | 0.167 | 0.398 |
ccnf |  | 1 | 164 | 306 | 313 | 0.165 | 0.174 | 0.125 | 0.235 | 0.089 | 0.068 | 0.057 | 0.220 | 0.167 | 0.116 | 0.156 | 0.128 | 0.358 |
GO Enrichment output for subnetwork 5518-6-real in each dataset
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.348E-06 | 5.4E-03 |
negative regulation of cellular protein metabolic process | GO:0032269 |  | 2.786E-06 | 3.204E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.995E-06 | 7.663E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 9.995E-06 | 5.747E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 9.995E-06 | 4.598E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.096E-05 | 8.036E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.096E-05 | 6.888E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.59E-05 | 7.447E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.73E-05 | 6.976E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.793E-05 | 6.425E-03 |
positive regulation of Ras GTPase activity | GO:0032320 |  | 2.793E-05 | 5.841E-03 |
IPC-NIBC-129 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 8.763E-07 | 2.141E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 4.364E-06 | 5.331E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 4.364E-06 | 3.554E-03 |
activation of Ras GTPase activity | GO:0032856 |  | 6.543E-06 | 3.996E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 9.157E-06 | 4.474E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 1.22E-05 | 4.969E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 1.317E-05 | 4.596E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 1.376E-05 | 4.203E-03 |
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 1.376E-05 | 3.736E-03 |
negative regulation of kinase activity | GO:0033673 |  | 1.437E-05 | 3.511E-03 |
positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 1.564E-05 | 3.474E-03 |
Ivshina_GPL96-GPL97 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 1.438E-06 | 3.459E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 6.077E-06 | 7.311E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 6.077E-06 | 4.874E-03 |
activation of Ras GTPase activity | GO:0032856 |  | 6.077E-06 | 3.655E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 1.275E-05 | 6.135E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 1.699E-05 | 6.813E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.06E-05 | 7.08E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.154E-05 | 6.477E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.154E-05 | 5.758E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.183E-05 | 5.253E-03 |
regulation of phosphoprotein phosphatase activity | GO:0043666 |  | 2.183E-05 | 4.776E-03 |
Loi_GPL570 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 8.763E-07 | 2.141E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 4.364E-06 | 5.331E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 4.364E-06 | 3.554E-03 |
activation of Ras GTPase activity | GO:0032856 |  | 6.543E-06 | 3.996E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 9.157E-06 | 4.474E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 1.22E-05 | 4.969E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 1.317E-05 | 4.596E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 1.376E-05 | 4.203E-03 |
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 1.376E-05 | 3.736E-03 |
negative regulation of kinase activity | GO:0033673 |  | 1.437E-05 | 3.511E-03 |
positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 1.564E-05 | 3.474E-03 |
Loi_GPL96-GPL97 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 1.438E-06 | 3.459E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 6.077E-06 | 7.311E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 6.077E-06 | 4.874E-03 |
activation of Ras GTPase activity | GO:0032856 |  | 6.077E-06 | 3.655E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 1.275E-05 | 6.135E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 1.699E-05 | 6.813E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.06E-05 | 7.08E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.154E-05 | 6.477E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.154E-05 | 5.758E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.183E-05 | 5.253E-03 |
regulation of phosphoprotein phosphatase activity | GO:0043666 |  | 2.183E-05 | 4.776E-03 |
Parker_GPL1390 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 1.323E-07 | 4.726E-04 |
negative regulation of protein ubiquitination | GO:0031397 |  | 1.933E-06 | 3.452E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.336E-06 | 2.78E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.454E-06 | 2.191E-03 |
negative regulation of transferase activity | GO:0051348 |  | 2.832E-06 | 2.023E-03 |
eukaryotic translation initiation factor 2B complex | GO:0005851 |  | 2.9E-06 | 1.726E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.9E-06 | 1.479E-03 |
regulation of phosphoprotein phosphatase activity | GO:0043666 |  | 4.058E-06 | 1.812E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 4.058E-06 | 1.61E-03 |
regulation of cell adhesion | GO:0030155 |  | 4.92E-06 | 1.757E-03 |
keratinocyte proliferation | GO:0043616 |  | 5.41E-06 | 1.756E-03 |
Parker_GPL887 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.069E-07 | 7.546E-04 |
positive regulation of cell-matrix adhesion | GO:0001954 |  | 1.597E-06 | 2.913E-03 |
RNA polymerase II carboxy-terminal domain kinase activity | GO:0008353 |  | 1.597E-06 | 1.942E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 1.915E-06 | 1.746E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.108E-06 | 1.538E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.21E-06 | 1.344E-03 |
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 2.21E-06 | 1.152E-03 |
eukaryotic translation initiation factor 2B complex | GO:0005851 |  | 2.395E-06 | 1.092E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.395E-06 | 9.708E-04 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 2.395E-06 | 8.737E-04 |
negative regulation of protein ubiquitination | GO:0031397 |  | 2.395E-06 | 7.943E-04 |
Pawitan_GPL96-GPL97 file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 1.438E-06 | 3.459E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 6.077E-06 | 7.311E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 6.077E-06 | 4.874E-03 |
activation of Ras GTPase activity | GO:0032856 |  | 6.077E-06 | 3.655E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 1.275E-05 | 6.135E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 1.699E-05 | 6.813E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.06E-05 | 7.08E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.154E-05 | 6.477E-03 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.154E-05 | 5.758E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.183E-05 | 5.253E-03 |
regulation of phosphoprotein phosphatase activity | GO:0043666 |  | 2.183E-05 | 4.776E-03 |
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.348E-06 | 5.4E-03 |
negative regulation of cellular protein metabolic process | GO:0032269 |  | 2.786E-06 | 3.204E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.995E-06 | 7.663E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 9.995E-06 | 5.747E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 9.995E-06 | 4.598E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.096E-05 | 8.036E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.096E-05 | 6.888E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.59E-05 | 7.447E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.73E-05 | 6.976E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.793E-05 | 6.425E-03 |
positive regulation of Ras GTPase activity | GO:0032320 |  | 2.793E-05 | 5.841E-03 |
Sotiriou file
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.348E-06 | 5.4E-03 |
negative regulation of cellular protein metabolic process | GO:0032269 |  | 2.786E-06 | 3.204E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.995E-06 | 7.663E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 9.995E-06 | 5.747E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 9.995E-06 | 4.598E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.096E-05 | 8.036E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.096E-05 | 6.888E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.59E-05 | 7.447E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.73E-05 | 6.976E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.793E-05 | 6.425E-03 |
positive regulation of Ras GTPase activity | GO:0032320 |  | 2.793E-05 | 5.841E-03 |
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.348E-06 | 5.4E-03 |
negative regulation of cellular protein metabolic process | GO:0032269 |  | 2.786E-06 | 3.204E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.995E-06 | 7.663E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 9.995E-06 | 5.747E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 9.995E-06 | 4.598E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.096E-05 | 8.036E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.096E-05 | 6.888E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.59E-05 | 7.447E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.73E-05 | 6.976E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.793E-05 | 6.425E-03 |
positive regulation of Ras GTPase activity | GO:0032320 |  | 2.793E-05 | 5.841E-03 |
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.348E-06 | 5.4E-03 |
negative regulation of cellular protein metabolic process | GO:0032269 |  | 2.786E-06 | 3.204E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.995E-06 | 7.663E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 9.995E-06 | 5.747E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 9.995E-06 | 4.598E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.096E-05 | 8.036E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.096E-05 | 6.888E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 2.59E-05 | 7.447E-03 |
negative regulation of kinase activity | GO:0033673 |  | 2.73E-05 | 6.976E-03 |
keratinocyte proliferation | GO:0043616 |  | 2.793E-05 | 6.425E-03 |
positive regulation of Ras GTPase activity | GO:0032320 |  | 2.793E-05 | 5.841E-03 |
Name | Accession Number | Link | P-val | Corrected P-val |
negative regulation of protein modification process | GO:0031400 |  | 2.804E-06 | 6.653E-03 |
negative regulation of protein ubiquitination | GO:0031397 |  | 9.59E-06 | 0.01137901 |
negative regulation of tyrosine phosphorylation of Stat3 protein | GO:0042518 |  | 9.59E-06 | 7.586E-03 |
positive regulation of Rho GTPase activity | GO:0032321 |  | 1.438E-05 | 8.529E-03 |
negative regulation of peptidyl-tyrosine phosphorylation | GO:0050732 |  | 1.438E-05 | 6.823E-03 |
negative regulation of JAK-STAT cascade | GO:0046426 |  | 2.68E-05 | 0.0106012 |
keratinocyte proliferation | GO:0043616 |  | 2.68E-05 | 9.087E-03 |
regulation of focal adhesion formation | GO:0051893 |  | 2.68E-05 | 7.951E-03 |
negative regulation of protein kinase activity | GO:0006469 |  | 3.167E-05 | 8.35E-03 |
negative regulation of kinase activity | GO:0033673 |  | 3.323E-05 | 7.886E-03 |
negative regulation of transferase activity | GO:0051348 |  | 3.822E-05 | 8.245E-03 |