Study run-a1
Study informations
119 subnetworks in total page | file
406 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 5373-6-real
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 |
|---|
| Desmedt | 0.1668 | 6.350e-03 | 7.564e-03 | 7.018e-02 |
|---|
| IPC-NIBC-129 | 0.2534 | 3.842e-02 | 4.806e-02 | 3.771e-01 |
|---|
| Ivshina_GPL96-GPL97 | 0.2703 | 6.996e-03 | 1.116e-02 | 2.115e-01 |
|---|
| Loi_GPL570 | 0.2597 | 5.870e-02 | 5.828e-02 | 2.865e-01 |
|---|
| Loi_GPL96-GPL97 | 0.1386 | 3.000e-06 | 2.400e-05 | 1.300e-05 |
|---|
| Parker_GPL1390 | 0.2774 | 1.553e-01 | 1.604e-01 | 6.598e-01 |
|---|
| Parker_GPL887 | 0.1305 | 5.451e-01 | 5.775e-01 | 5.866e-01 |
|---|
| Pawitan_GPL96-GPL97 | 0.3576 | 9.604e-02 | 6.978e-02 | 5.058e-01 |
|---|
| Schmidt | 0.2553 | 1.426e-02 | 2.006e-02 | 1.712e-01 |
|---|
| Sotiriou | 0.2935 | 1.395e-03 | 3.460e-04 | 4.061e-02 |
|---|
| Wang | 0.2010 | 1.556e-01 | 1.152e-01 | 4.825e-01 |
|---|
| Zhang | 0.2751 | 7.742e-02 | 4.821e-02 | 1.910e-01 |
|---|
| Zhou | 0.4479 | 6.276e-02 | 6.653e-02 | 3.866e-01 |
|---|
Expression data for subnetwork 5373-6-real in each dataset
Desmedt |
IPC-NIBC-129 |
Ivshina_GPL96-GPL97 |
Loi_GPL570 |
Loi_GPL96-GPL97 |
Parker_GPL1390 |
Parker_GPL887 |
Pawitan_GPL96-GPL97 |
Schmidt |
Sotiriou |
Wang |
Zhang |
Zhou |
Subnetwork structure for each dataset
- Desmedt
Score for each gene in subnetwork 5373-6-real in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Wang | Zhang | Zhou |
|---|
| pin1 |   | 4 | 60 | 141 | 130 | -0.012 | 0.181 | 0.133 | 0.270 | 0.112 | 0.074 | -0.085 | 0.072 | 0.063 | 0.161 | 0.033 | 0.259 | 0.019 |
|---|
| rap1gap | | 1 | 164 | 141 | 152 | 0.019 | 0.060 | 0.005 | 0.138 | 0.092 | 0.049 | 0.059 | 0.094 | 0.015 | -0.030 | -0.024 | 0.009 | 0.072 |
|---|
| pmm2 | | 1 | 164 | 141 | 152 | 0.090 | 0.089 | 0.070 | -0.117 | 0.078 | 0.058 | 0.250 | 0.184 | 0.040 | 0.023 | 0.140 | 0.083 | 0.141 |
|---|
| cdkn1a | | 70 | 3 | 73 | 51 | 0.115 | -0.020 | 0.065 | 0.082 | 0.099 | 0.124 | 0.055 | 0.087 | 0.068 | 0.144 | 0.015 | -0.201 | 0.069 |
|---|
| cep55 | | 3 | 79 | 141 | 137 | 0.054 | 0.210 | 0.148 | 0.129 | 0.135 | 0.162 | 0.133 | 0.209 | 0.202 | 0.138 | 0.144 | 0.115 | 0.330 |
|---|
| plk1 | | 6 | 43 | 141 | 122 | 0.067 | 0.281 | 0.012 | 0.128 | 0.123 | 0.100 | 0.577 | 0.100 | 0.190 | 0.044 | 0.028 | 0.040 | 0.410 |
|---|
| lars2 | | 1 | 164 | 141 | 152 | 0.076 | 0.092 | 0.152 | -0.129 | 0.068 | -0.097 | 0.220 | 0.131 | 0.168 | 0.066 | 0.110 | 0.273 | 0.352 |
|---|
| ccnd1 | | 102 | 2 | 1 | 2 | 0.127 | -0.183 | 0.062 | 0.190 | 0.157 | -0.002 | -0.190 | 0.105 | -0.107 | 0.174 | 0.106 | 0.144 | 0.290 |
|---|
| kars | | 2 | 104 | 141 | 144 | 0.062 | 0.134 | 0.180 | 0.033 | 0.120 | 0.159 | -0.154 | 0.152 | 0.186 | 0.204 | 0.129 | 0.017 | 0.283 |
|---|
| tsc1 | | 47 | 5 | 17 | 8 | 0.049 | 0.012 | -0.055 | 0.072 | 0.055 | -0.144 | -0.242 | -0.196 | 0.006 | 0.010 | 0.043 | -0.007 | 0.207 |
|---|
| map4 | | 16 | 13 | 73 | 55 | 0.002 | 0.046 | 0.067 | -0.043 | 0.034 | 0.119 | 0.159 | -0.058 | -0.020 | 0.043 | 0.108 | -0.074 | 0.302 |
|---|
| cdc2 | | 103 | 1 | 1 | 1 | 0.073 | 0.247 | 0.206 | 0.172 | 0.247 | 0.153 | -0.131 | 0.282 | 0.226 | 0.221 | 0.067 | 0.297 | 0.336 |
|---|
| sfn | | 50 | 4 | 29 | 17 | 0.077 | 0.137 | 0.111 | 0.172 | 0.112 | 0.119 | 0.141 | 0.219 | 0.100 | 0.147 | 0.025 | 0.079 | 0.181 |
|---|
| eif2s1 | | 14 | 17 | 73 | 57 | -0.031 | 0.151 | 0.253 | 0.182 | 0.098 | 0.167 | 0.005 | 0.270 | 0.233 | 0.038 | 0.122 | 0.239 | 0.265 |
|---|
| ict1 | | 1 | 164 | 141 | 152 | -0.063 | 0.113 | 0.138 | 0.097 | 0.213 | 0.147 | 0.188 | 0.166 | 0.062 | 0.147 | -0.022 | 0.151 | 0.197 |
|---|
GO Enrichment output for subnetwork 5373-6-real in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 1.073E-06 | 2.468E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.291E-05 | 0.02634115 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 2.291E-05 | 0.01756077 |
|---|
| amino acid activation | GO:0043038 | | 2.465E-05 | 0.01417291 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.125E-05 | 0.01437287 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.891E-05 | 0.0149147 |
|---|
| response to UV | GO:0009411 | | 4.771E-05 | 0.01567646 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.801E-05 | 0.01380275 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 4.801E-05 | 0.01226912 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.395E-05 | 0.01470891 |
|---|
| positive regulation of B cell proliferation | GO:0030890 | | 6.395E-05 | 0.01337173 |
|---|
IPC-NIBC-129 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.066E-07 | 5.047E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.839E-06 | 9.575E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 9.166E-06 | 7.464E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 9.8E-06 | 5.985E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 1.175E-05 | 5.742E-03 |
|---|
| amino acid activation | GO:0043038 | | 1.421E-05 | 5.788E-03 |
|---|
| response to UV | GO:0009411 | | 1.684E-05 | 5.878E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 2.191E-05 | 6.691E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 2.191E-05 | 5.948E-03 |
|---|
| regulation of phosphoprotein phosphatase activity | GO:0043666 | | 2.816E-05 | 6.879E-03 |
|---|
| mannose metabolic process | GO:0006013 | | 2.816E-05 | 6.253E-03 |
|---|
Ivshina_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 3.984E-07 | 9.586E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 1.092E-05 | 0.01313115 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 1.092E-05 | 8.754E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.5E-05 | 9.022E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.603E-05 | 7.715E-03 |
|---|
| amino acid activation | GO:0043038 | | 2.324E-05 | 9.32E-03 |
|---|
| response to UV | GO:0009411 | | 2.462E-05 | 8.462E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 3.05E-05 | 9.174E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 3.05E-05 | 8.154E-03 |
|---|
| keratinocyte proliferation | GO:0043616 | | 3.919E-05 | 9.429E-03 |
|---|
| regulation of phosphoprotein phosphatase activity | GO:0043666 | | 3.919E-05 | 8.572E-03 |
|---|
Loi_GPL570 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.066E-07 | 5.047E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 7.839E-06 | 9.575E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 9.166E-06 | 7.464E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 9.8E-06 | 5.985E-03 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 1.175E-05 | 5.742E-03 |
|---|
| amino acid activation | GO:0043038 | | 1.421E-05 | 5.788E-03 |
|---|
| response to UV | GO:0009411 | | 1.684E-05 | 5.878E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 2.191E-05 | 6.691E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 2.191E-05 | 5.948E-03 |
|---|
| regulation of phosphoprotein phosphatase activity | GO:0043666 | | 2.816E-05 | 6.879E-03 |
|---|
| mannose metabolic process | GO:0006013 | | 2.816E-05 | 6.253E-03 |
|---|
Loi_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 3.984E-07 | 9.586E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 1.092E-05 | 0.01313115 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 1.092E-05 | 8.754E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.5E-05 | 9.022E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.603E-05 | 7.715E-03 |
|---|
| amino acid activation | GO:0043038 | | 2.324E-05 | 9.32E-03 |
|---|
| response to UV | GO:0009411 | | 2.462E-05 | 8.462E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 3.05E-05 | 9.174E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 3.05E-05 | 8.154E-03 |
|---|
| keratinocyte proliferation | GO:0043616 | | 3.919E-05 | 9.429E-03 |
|---|
| regulation of phosphoprotein phosphatase activity | GO:0043666 | | 3.919E-05 | 8.572E-03 |
|---|
Parker_GPL1390 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 | | 3.814E-08 | 1.362E-04 |
|---|
| cyclin-dependent protein kinase regulator activity | GO:0016538 | | 1.122E-07 | 2.003E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.145E-07 | 1.363E-04 |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 2.471E-07 | 2.206E-04 |
|---|
| protein kinase regulator activity | GO:0019887 | | 3.136E-07 | 2.24E-04 |
|---|
| kinase regulator activity | GO:0019207 | | 6.633E-07 | 3.947E-04 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 2.206E-06 | 1.125E-03 |
|---|
| kinase inhibitor activity | GO:0019210 | | 2.731E-06 | 1.219E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 8.241E-06 | 3.27E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 8.371E-06 | 2.989E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.012E-05 | 3.285E-03 |
|---|
Parker_GPL887 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 | | 2.861E-08 | 1.044E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 8.679E-08 | 1.583E-04 |
|---|
| cyclin-dependent protein kinase regulator activity | GO:0016538 | | 1.854E-07 | 2.254E-04 |
|---|
| protein kinase regulator activity | GO:0019887 | | 2.484E-07 | 2.265E-04 |
|---|
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 | | 2.64E-07 | 1.926E-04 |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 2.849E-07 | 1.732E-04 |
|---|
| positive regulation of ligase activity | GO:0051351 | | 3.154E-07 | 1.643E-04 |
|---|
| regulation of ubiquitin-protein ligase activity | GO:0051438 | | 4.17E-07 | 1.901E-04 |
|---|
| kinase regulator activity | GO:0019207 | | 4.399E-07 | 1.783E-04 |
|---|
| regulation of ligase activity | GO:0051340 | | 4.886E-07 | 1.782E-04 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 3.016E-06 | 1E-03 |
|---|
Pawitan_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 3.984E-07 | 9.586E-04 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 1.092E-05 | 0.01313115 |
|---|
| activation of Ras GTPase activity | GO:0032856 | | 1.092E-05 | 8.754E-03 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.5E-05 | 9.022E-03 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.603E-05 | 7.715E-03 |
|---|
| amino acid activation | GO:0043038 | | 2.324E-05 | 9.32E-03 |
|---|
| response to UV | GO:0009411 | | 2.462E-05 | 8.462E-03 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 3.05E-05 | 9.174E-03 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 3.05E-05 | 8.154E-03 |
|---|
| keratinocyte proliferation | GO:0043616 | | 3.919E-05 | 9.429E-03 |
|---|
| regulation of phosphoprotein phosphatase activity | GO:0043666 | | 3.919E-05 | 8.572E-03 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.073E-06 | 2.468E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.291E-05 | 0.02634115 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 2.291E-05 | 0.01756077 |
|---|
| amino acid activation | GO:0043038 | | 2.465E-05 | 0.01417291 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.125E-05 | 0.01437287 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.891E-05 | 0.0149147 |
|---|
| response to UV | GO:0009411 | | 4.771E-05 | 0.01567646 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.801E-05 | 0.01380275 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 4.801E-05 | 0.01226912 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.395E-05 | 0.01470891 |
|---|
| positive regulation of B cell proliferation | GO:0030890 | | 6.395E-05 | 0.01337173 |
|---|
Sotiriou file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.073E-06 | 2.468E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.291E-05 | 0.02634115 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 2.291E-05 | 0.01756077 |
|---|
| amino acid activation | GO:0043038 | | 2.465E-05 | 0.01417291 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.125E-05 | 0.01437287 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.891E-05 | 0.0149147 |
|---|
| response to UV | GO:0009411 | | 4.771E-05 | 0.01567646 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.801E-05 | 0.01380275 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 4.801E-05 | 0.01226912 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.395E-05 | 0.01470891 |
|---|
| positive regulation of B cell proliferation | GO:0030890 | | 6.395E-05 | 0.01337173 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.073E-06 | 2.468E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.291E-05 | 0.02634115 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 2.291E-05 | 0.01756077 |
|---|
| amino acid activation | GO:0043038 | | 2.465E-05 | 0.01417291 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.125E-05 | 0.01437287 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.891E-05 | 0.0149147 |
|---|
| response to UV | GO:0009411 | | 4.771E-05 | 0.01567646 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.801E-05 | 0.01380275 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 4.801E-05 | 0.01226912 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.395E-05 | 0.01470891 |
|---|
| positive regulation of B cell proliferation | GO:0030890 | | 6.395E-05 | 0.01337173 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.073E-06 | 2.468E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.291E-05 | 0.02634115 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 2.291E-05 | 0.01756077 |
|---|
| amino acid activation | GO:0043038 | | 2.465E-05 | 0.01417291 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.125E-05 | 0.01437287 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.891E-05 | 0.0149147 |
|---|
| response to UV | GO:0009411 | | 4.771E-05 | 0.01567646 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.801E-05 | 0.01380275 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 4.801E-05 | 0.01226912 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.395E-05 | 0.01470891 |
|---|
| positive regulation of B cell proliferation | GO:0030890 | | 6.395E-05 | 0.01337173 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.17E-06 | 2.776E-03 |
|---|
| negative regulation of protein ubiquitination | GO:0031397 | | 2.193E-05 | 0.02602574 |
|---|
| positive regulation of Rho GTPase activity | GO:0032321 | | 3.287E-05 | 0.02600132 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.417E-05 | 0.02027221 |
|---|
| amino acid activation | GO:0043038 | | 3.67E-05 | 0.01741637 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 3.934E-05 | 0.01555977 |
|---|
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 | | 4.598E-05 | 0.01558615 |
|---|
| response to UV | GO:0009411 | | 4.802E-05 | 0.01424414 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.124E-05 | 0.01614825 |
|---|
| keratinocyte proliferation | GO:0043616 | | 6.124E-05 | 0.01453343 |
|---|
| regulation of focal adhesion formation | GO:0051893 | | 6.124E-05 | 0.0132122 |
|---|
