pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/9551-11-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mRNA cleavage GO:0006379 13 9 2,000 2,743E-07 6,308E-04 ! mRNA polyadenylation GO:0006378 18 10 2,000 3,914E-07 4,501E-04 ! RNA polyadenylation GO:0043631 19 11 2,000 5,376E-07 4,122E-04 ! mRNA 3'-end processing GO:0031124 19 11 2,000 5,376E-07 3,091E-04 ! RNA 3'-end processing GO:0031123 20 12 2,000 7,161E-07 3,294E-04 ! collagen catabolic process GO:0030574 25 20 2,000 3,68E-06 1,411E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 4,289E-06 1,409E-03 ! multicellular organismal catabolic process GO:0044243 32 26 2,000 8,342E-06 2,398E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 8,787E-06 2,245E-03 ! interphase GO:0051325 159 88 3,000 9,628E-06 2,215E-03 ! collagen metabolic process GO:0032963 40 30 2,000 1,297E-05 2,712E-03 ! spliceosome assembly GO:0000245 49 30 2,000 1,297E-05 2,486E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 2,000 1,738E-05 3,075E-03 ! multicellular organismal metabolic process GO:0044236 50 39 2,000 2,893E-05 4,753E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 3,891E-05 5,966E-03 ! ribonucleoprotein complex assembly GO:0022618 70 44 2,000 4,171E-05 5,996E-03 ! response to UV GO:0009411 75 46 2,000 4,771E-05 6,455E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,801E-05 6,135E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,395E-05 7,742E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,395E-05 7,354E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 6,512E-05 7,132E-03 ! thymus development GO:0048538 15 9 1,000 8,215E-05 8,588E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,026E-04 0,01025838 ! T cell homeostasis GO:0043029 20 11 1,000 1,253E-04 0,01200415 ! lymphocyte homeostasis GO:0002260 24 13 1,000 1,773E-04 0,01631198 ! DNA unwinding during replication GO:0006268 21 14 1,000 2,067E-04 0,01828127 ! mRNA splice site selection GO:0006376 26 14 1,000 2,067E-04 0,01760418 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,72E-04 0,0223426 GO:0030968|endoplasmic reticulum unfolded protein response, ! DNA replication initiation GO:0006270 25 16 1,000 2,72E-04 0,02157216 ! DNA duplex unwinding GO:0032508 25 17 1,000 3,08E-04 0,02361099 GO:0032392|DNA geometric change, ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,865E-04 0,028675 ! response to light stimulus GO:0009416 153 96 2,000 4,266E-04 0,03065903 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,29E-04 0,02990164 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 4,737E-04 0,0320466 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 4,737E-04 0,03113098 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,206E-04 0,03326116 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 5,206E-04 0,03236221 ! leukocyte homeostasis GO:0001776 33 22 1,000 5,206E-04 0,03151057 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 5,696E-04 0,03359465 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 5,696E-04 0,03275479 ! fat cell differentiation GO:0045444 37 24 1,000 6,208E-04 0,03482779 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 6,742E-04 0,03691977 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of B cell activation GO:0050864 42 28 1,000 8,471E-04 0,04530747 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 1,000 1,039E-03 0,05431334 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,324E-03 0,06769513 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to calcium ion GO:0051592 58 40 1,000 1,728E-03 0,08640203 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 1,728E-03 0,08456369 ! ATP synthesis coupled electron transport GO:0042773 48 40 1,000 1,728E-03 0,08280194 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! DNA-dependent DNA replication GO:0006261 59 43 1,000 1,995E-03 0,09363533 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,088E-03 0,0960409 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,183E-03 0,09844353 ! respiratory electron transport chain GO:0022904 59 47 1,000 2,379E-03 0,10522495 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,379E-03 0,10323957 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! proton transport GO:0015992 75 50 1,000 2,688E-03 0,11449862 ! hydrogen transport GO:0006818 77 51 1,000 2,795E-03 0,11689413 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 3,479E-03 0,14289409 ! negative regulation of kinase activity GO:0033673 100 58 1,000 3,6E-03 0,14526296 ! homeostasis of number of cells GO:0048872 84 61 1,000 3,974E-03 0,15759507 ! negative regulation of transferase activity GO:0051348 105 61 1,000 3,974E-03 0,15492397 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 3,974E-03 0,15234191 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,103E-03 0,15469236 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 4,103E-03 0,15219732 ! negative regulation of cell size GO:0045792 108 64 1,000 4,366E-03 0,1593795 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 4,366E-03 0,1568892 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 4,5E-03 0,15922827 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 4,5E-03 0,15681572 ! positive regulation of ligase activity GO:0051351 99 69 1,000 5,056E-03 0,17356997 ! response to metal ion GO:0010038 103 70 1,000 5,2E-03 0,17588041 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,2E-03 0,17333142 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 5,346E-03 0,17564085 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 5,493E-03 0,17794575 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 5,794E-03 0,18507731 ! response to inorganic substance GO:0010035 115 75 1,000 5,947E-03 0,18736534 ! negative regulation of growth GO:0045926 123 75 1,000 5,947E-03 0,18483338 ! regulation of ligase activity GO:0051340 114 75 1,000 5,947E-03 0,18236893 ! response to unfolded protein GO:0006986 99 76 1,000 6,102E-03 0,18465815 ! positive regulation of protein modification process GO:0031401 107 78 1,000 6,417E-03 0,19168056 ! cellular respiration GO:0045333 107 79 1,000 6,578E-03 0,19395399 ! oxidative phosphorylation GO:0006119 105 79 1,000 6,578E-03 0,19149888 ! ATP biosynthetic process GO:0006754 118 79 1,000 6,578E-03 0,18910514 ! chromatin assembly GO:0031497 102 80 1,000 6,74E-03 0,19137795 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 6,74E-03 0,18904407 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 6,904E-03 0,19131323 ! positive regulation of cell activation GO:0050867 120 81 1,000 6,904E-03 0,18903569 GO:0002696|positive regulation of leukocyte activation, ! protein-DNA complex assembly GO:0065004 107 84 1,000 7,407E-03 0,2004248 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,699E-03 0,20591126 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 7,699E-03 0,20354446 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 7,699E-03 0,20123145 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 7,699E-03 0,19897043 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 7,699E-03 0,19675964 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,699E-03 0,19459745 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 7,699E-03 0,19248226 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,699E-03 0,19041256 ! sleep GO:0030431 11 5 0,000 7,699E-03 0,18838689 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,699E-03 0,18640387 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,699E-03 0,18446217 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,699E-03 0,18256049 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 7,699E-03 0,18069763 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 7,699E-03 0,1788724 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 7,699E-03 0,17708368 ! tongue development GO:0043586 6 5 0,000 7,699E-03 0,17533038 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 7,699E-03 0,17361145 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,699E-03 0,1719259 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 7,699E-03 0,17027277 ! cobalt ion transport GO:0006824 9 5 0,000 7,699E-03 0,16865112 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,699E-03 0,16706008 ! SMAD protein complex assembly GO:0007183 9 5 0,000 7,699E-03 0,16549877 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,699E-03 0,16396637 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,699E-03 0,16246209 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 7,699E-03 0,16098516 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,699E-03 0,15953485 ! embryonic camera-type eye development GO:0031076 8 5 0,000 7,699E-03 0,15811043 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 7,699E-03 0,15671122 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 7,699E-03 0,15533656 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,699E-03 0,15398581 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,699E-03 0,15265834 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,699E-03 0,15135357 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 7,699E-03 0,15007091 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 7,699E-03 0,14880981 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,699E-03 0,14756973 ! malate metabolic process GO:0006108 7 5 0,000 7,699E-03 0,14635015 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 7,699E-03 0,14515056 ! behavioral response to pain GO:0048266 7 5 0,000 7,699E-03 0,14397047 ! clathrin coat assembly GO:0048268 11 5 0,000 7,699E-03 0,14280942 ! phototransduction, visible light GO:0007603 6 5 0,000 7,699E-03 0,14166694 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,699E-03 0,1405426 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,699E-03 0,13943597 ! mating behavior GO:0007617 6 5 0,000 7,699E-03 0,13834662 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,699E-03 0,13727417 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,699E-03 0,13621822 ! rhythmic behavior GO:0007622 12 5 0,000 7,699E-03 0,13517838 ! copulation GO:0007620 7 5 0,000 7,699E-03 0,1341543 ! glial cell fate commitment GO:0021781 12 5 0,000 7,699E-03 0,13314562 ! protein maturation by protein folding GO:0022417 12 5 0,000 7,699E-03 0,132152 ! embryonic hemopoiesis GO:0035162 10 5 0,000 7,699E-03 0,1311731 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,699E-03 0,13020859 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 7,699E-03 0,12925816 ! apoptotic cell clearance GO:0043277 13 5 0,000 7,699E-03 0,12832151 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,699E-03 0,12739833 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 7,699E-03 0,12648834 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,699E-03 0,12559126 ! response to protozoan GO:0001562 9 5 0,000 7,699E-03 0,12470682 ! positive regulation of glycolysis GO:0045821 11 5 0,000 7,699E-03 0,12383474 ! lymph vessel development GO:0001945 7 5 0,000 7,699E-03 0,12297478 ! endochondral ossification GO:0001958 12 5 0,000 7,699E-03 0,12212668 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,699E-03 0,12129019 ! parathyroid gland development GO:0060017 8 5 0,000 7,699E-03 0,12046509 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 7,699E-03 0,11965113 ! anagen GO:0042640 6 5 0,000 7,699E-03 0,11884811 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,699E-03 0,11805579 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,699E-03 0,11727396 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 7,699E-03 0,11650242 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 7,699E-03 0,11574097 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,699E-03 0,1149894 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 7,699E-03 0,11424754 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 7,699E-03 0,11351518 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 7,699E-03 0,11279215 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,699E-03 0,11207828 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,699E-03 0,11137338 ! cardiac muscle fiber development GO:0048739 7 5 0,000 7,699E-03 0,1106773 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 7,699E-03 0,10998986 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 7,699E-03 0,10931091 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,699E-03 0,10864029 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,699E-03 0,10797785 ! ovulation GO:0030728 6 5 0,000 7,699E-03 0,10732344 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,699E-03 0,10667692 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 7,699E-03 0,10603813 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,699E-03 0,10540695 ! response to pH GO:0009268 9 5 0,000 7,699E-03 0,10478324 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,699E-03 0,10416687 ! proline biosynthetic process GO:0006561 6 5 0,000 7,699E-03 0,10355771 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,699E-03 0,10295563 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 7,699E-03 0,10236051 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,699E-03 0,10177223 ! polyol catabolic process GO:0046174 7 5 0,000 7,699E-03 0,10119067 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,699E-03 0,10061573 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,699E-03 0,10004728 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,699E-03 0,09948521 ! sister chromatid cohesion GO:0007062 9 5 0,000 7,699E-03 0,09892943 ! nerve growth factor processing GO:0032455 7 5 0,000 7,699E-03 0,09837982 ! urea metabolic process GO:0019627 6 5 0,000 7,699E-03 0,09783629 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 7,699E-03 0,09729873 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,699E-03 0,09676704 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 7,699E-03 0,09624113 ! neutrophil activation GO:0042119 5 5 0,000 7,699E-03 0,09572091 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,699E-03 0,09520628 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,699E-03 0,09469715 ! response to food GO:0032094 5 5 0,000 7,699E-03 0,09419345 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,699E-03 0,09369507 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,699E-03 0,09320194 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,699E-03 0,09271397 ! forebrain neuron development GO:0021884 7 5 0,000 7,699E-03 0,09223108 ! melanosome organization GO:0032438 7 5 0,000 7,699E-03 0,0917532 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,699E-03 0,09128025 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,699E-03 0,09081214 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 7,699E-03 0,09034882 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,699E-03 0,08989019 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 7,699E-03 0,0894362 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 7,699E-03 0,08898677 ! nucleoside transport GO:0015858 6 5 0,000 7,699E-03 0,08854184 ! nucleoside salvage GO:0043174 7 5 0,000 7,699E-03 0,08810133 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 7,699E-03 0,08766519 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,699E-03 0,08723334 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 7,699E-03 0,08680573 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,699E-03 0,08638228 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,699E-03 0,08596295 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,699E-03 0,08554767 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,699E-03 0,08513638 ! depyrimidination GO:0045008 8 5 0,000 7,699E-03 0,08472903 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 7,699E-03 0,08432556 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,699E-03 0,08392591 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 7,699E-03 0,08353004 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,699E-03 0,08313788 ! neuronal ion channel clustering GO:0045161 7 5 0,000 7,699E-03 0,08274938 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,699E-03 0,0823645 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 7,699E-03 0,08198319 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 7,699E-03 0,08160538 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,699E-03 0,08123105 ! monocyte differentiation GO:0030224 8 5 0,000 7,699E-03 0,08086013 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 7,699E-03 0,08049258 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 7,699E-03 0,08012836 ! centrosome duplication GO:0051298 5 5 0,000 7,699E-03 0,07976742 ! response to UV-C GO:0010225 6 5 0,000 7,699E-03 0,07940972 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,699E-03 0,07905521 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 7,699E-03 0,07870386 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,699E-03 0,07835561 ! regulation of dendrite development GO:0050773 12 5 0,000 7,699E-03 0,07801043 ! peptidyl-arginine modification GO:0018195 7 5 0,000 7,699E-03 0,07766828 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,699E-03 0,07732912 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 7,699E-03 0,0769929 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 7,699E-03 0,0766596 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 7,699E-03 0,07632917 ! regulation of dopamine secretion GO:0014059 12 5 0,000 7,699E-03 0,07600158 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,699E-03 0,07567679 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 7,699E-03 0,07535476 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,699E-03 0,07503546 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,699E-03 0,07471885 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 7,699E-03 0,07440491 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,699E-03 0,07409359 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 7,699E-03 0,07378487 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 7,699E-03 0,07347871 ! neural tube patterning GO:0021532 6 5 0,000 7,699E-03 0,07317507 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,699E-03 0,07287394 ! histone demethylation GO:0016577 9 5 0,000 7,699E-03 0,07257528 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,699E-03 0,07227905 ! regulation of sterol transport GO:0032371 7 5 0,000 7,699E-03 0,07198524 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,699E-03 0,0716938 ! enteric nervous system development GO:0048484 8 5 0,000 7,699E-03 0,07140471 ! establishment of planar polarity GO:0001736 6 5 0,000 7,699E-03 0,07111794 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,699E-03 0,07083347 ! muscle cell proliferation GO:0033002 8 5 0,000 7,699E-03 0,07055127 ! transcription termination GO:0006353 8 5 0,000 7,699E-03 0,0702713 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 7,699E-03 0,06999355 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 7,699E-03 0,06971798 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 7,699E-03 0,06944458 ! regulation of respiratory burst GO:0060263 8 5 0,000 7,699E-03 0,06917331 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,699E-03 0,06890416 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,699E-03 0,06863709 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,699E-03 0,06837208 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 7,699E-03 0,06810911 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,699E-03 0,06784815 ! apical protein localization GO:0045176 6 5 0,000 7,699E-03 0,06758919 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,699E-03 0,0673322 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,699E-03 0,06707715 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,699E-03 0,06682403 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,699E-03 0,06657281 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 7,699E-03 0,06632348 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 7,699E-03 0,066076 ! triglyceride catabolic process GO:0019433 6 5 0,000 7,699E-03 0,06583036 ! glial cell migration GO:0008347 10 5 0,000 7,699E-03 0,06558655 ! determination of adult lifespan GO:0008340 8 5 0,000 7,699E-03 0,06534453 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,699E-03 0,06510429 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,699E-03 0,06486582 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,699E-03 0,06462908 ! somatic stem cell maintenance GO:0035019 13 5 0,000 7,699E-03 0,06439407 ! cerebellar cortex formation GO:0021697 6 5 0,000 7,699E-03 0,06416075 ! neural plate development GO:0001840 6 5 0,000 7,699E-03 0,06392913 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 7,699E-03 0,06369917 ! regulation of sensory perception GO:0051931 6 5 0,000 7,699E-03 0,06347085 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 7,699E-03 0,06324417 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 7,699E-03 0,0630191 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 7,699E-03 0,06279563 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 7,699E-03 0,06257374 ! sensory cilium assembly GO:0035058 6 5 0,000 7,699E-03 0,06235341 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 7,699E-03 0,06213462 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,699E-03 0,06191737 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 7,699E-03 0,06170163 ! spindle assembly GO:0051225 5 5 0,000 7,699E-03 0,06148739 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 7,699E-03 0,06127463 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 7,699E-03 0,06106334 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,699E-03 0,0608535 ! organ regeneration GO:0031100 7 5 0,000 7,699E-03 0,0606451 ! NAD biosynthetic process GO:0009435 7 5 0,000 7,699E-03 0,06043812 ! carnitine metabolic process GO:0009437 5 5 0,000 7,699E-03 0,06023254 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 7,699E-03 0,06002837 ! cellular anion homeostasis GO:0030002 6 5 0,000 7,699E-03 0,05982557 GO:0055081|anion homeostasis, ! cell cycle arrest GO:0007050 150 86 1,000 7,751E-03 0,06002756 ! nucleosome organization GO:0034728 114 87 1,000 7,926E-03 0,0611758 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 1,000 7,926E-03 0,0609712 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 8,103E-03 0,06212228 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 8,281E-03 0,06327926 ! ATP metabolic process GO:0046034 137 91 1,000 8,643E-03 0,06582779 ! electron transport chain GO:0022900 123 94 1,000 9,2E-03 0,06983392 ! response to oxidative stress GO:0006979 141 94 1,000 9,2E-03 0,0696042 ! tRNA transcription GO:0009304 11 6 0,000 9,232E-03 0,0696205 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,232E-03 0,06939298 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,232E-03 0,06916694 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,232E-03 0,06894238 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,232E-03 0,06871926 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,232E-03 0,06849759 ! regulation of helicase activity GO:0051095 11 6 0,000 9,232E-03 0,06827734 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,232E-03 0,0680585 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,232E-03 0,06784106 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,232E-03 0,06762501 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,232E-03 0,06741032 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,232E-03 0,067197 ! prostate gland development GO:0030850 9 6 0,000 9,232E-03 0,06698502 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,232E-03 0,06677438 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,232E-03 0,06656505 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,232E-03 0,06635704 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,232E-03 0,06615032 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,232E-03 0,06594488 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,232E-03 0,06574072 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,232E-03 0,06553781 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,232E-03 0,06533616 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,232E-03 0,06513574 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,232E-03 0,06493655 ! neuron adhesion GO:0007158 9 6 0,000 9,232E-03 0,06473857 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,232E-03 0,0645418 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,232E-03 0,06434622 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,232E-03 0,06415182 ! signal peptide processing GO:0006465 8 6 0,000 9,232E-03 0,06395859 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,232E-03 0,06376652 ! mRNA stabilization GO:0048255 15 6 0,000 9,232E-03 0,0635756 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,232E-03 0,06338583 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,232E-03 0,06319718 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,232E-03 0,06300965 ! opsonization GO:0008228 8 6 0,000 9,232E-03 0,06282323 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,232E-03 0,06263791 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,232E-03 0,06245368 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,232E-03 0,06227053 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,232E-03 0,06208846 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,232E-03 0,06190744 ! photoreceptor cell development GO:0042461 10 6 0,000 9,232E-03 0,06172748 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,232E-03 0,06154856 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,232E-03 0,06137067 ! mechanosensory behavior GO:0007638 8 6 0,000 9,232E-03 0,06119381 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,232E-03 0,06101797 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,232E-03 0,06084313 ! response to interferon-gamma GO:0034341 12 6 0,000 9,232E-03 0,06066929 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,232E-03 0,06049644 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,232E-03 0,06032458 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,232E-03 0,06015369 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,232E-03 0,05998376 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,232E-03 0,05981479 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,232E-03 0,05964678 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,232E-03 0,0594797 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,232E-03 0,05931355 ! thymic T cell selection GO:0045061 12 6 0,000 9,232E-03 0,05914833 ! protein lipoylation GO:0009249 10 6 0,000 9,232E-03 0,05898403 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,232E-03 0,05882064 ! pigment granule organization GO:0048753 11 6 0,000 9,232E-03 0,05865815 ! drug transport GO:0015893 6 6 0,000 9,232E-03 0,05849656 ! cysteine metabolic process GO:0006534 7 6 0,000 9,232E-03 0,05833586 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,232E-03 0,05817603 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,232E-03 0,05801708 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,232E-03 0,057859 ! histidine metabolic process GO:0006547 6 6 0,000 9,232E-03 0,05770177 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,232E-03 0,0575454 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,232E-03 0,05738987 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,232E-03 0,05723518 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,232E-03 0,05708132 ! adenohypophysis development GO:0021984 10 6 0,000 9,232E-03 0,05692829 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,232E-03 0,05677607 ! hyperosmotic response GO:0006972 8 6 0,000 9,232E-03 0,05662467 ! microtubule nucleation GO:0007020 10 6 0,000 9,232E-03 0,05647407 ! ER overload response GO:0006983 7 6 0,000 9,232E-03 0,05632428 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,232E-03 0,05617527 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,232E-03 0,05602705 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,232E-03 0,05587961 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,232E-03 0,05573294 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,232E-03 0,05558705 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,232E-03 0,05544191 ! response to dietary excess GO:0002021 7 6 0,000 9,232E-03 0,05529753 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,232E-03 0,0551539 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,232E-03 0,05501102 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,232E-03 0,05486887 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,232E-03 0,05472745 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,232E-03 0,05458677 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,232E-03 0,0544468 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,232E-03 0,05430755 ! neuron apoptosis GO:0051402 8 6 0,000 9,232E-03 0,05416901 ! organic alcohol transport GO:0015850 9 6 0,000 9,232E-03 0,05403118 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,232E-03 0,05389404 ! T cell mediated immunity GO:0002456 12 6 0,000 9,232E-03 0,0537576 ! male sex determination GO:0030238 9 6 0,000 9,232E-03 0,05362185 ! carnitine transport GO:0015879 8 6 0,000 9,232E-03 0,05348678 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,232E-03 0,05335239 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,232E-03 0,05321868 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,232E-03 0,05308563 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,232E-03 0,05295325 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,232E-03 0,05282152 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,232E-03 0,05269045 ! parturition GO:0007567 12 6 0,000 9,232E-03 0,05256003 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,232E-03 0,05243025 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,232E-03 0,05230111 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,232E-03 0,05217261 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,232E-03 0,05204474 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,232E-03 0,05191749 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,232E-03 0,05179086 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,232E-03 0,05166485 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,232E-03 0,05153945 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,232E-03 0,05141465 ! macrophage differentiation GO:0030225 10 6 0,000 9,232E-03 0,05129046 ! astrocyte development GO:0014002 14 6 0,000 9,232E-03 0,05116687 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,232E-03 0,05104387 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,232E-03 0,05092147 ! interaction with symbiont GO:0051702 8 6 0,000 9,232E-03 0,05079965 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,232E-03 0,05067841 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,232E-03 0,05055774 ! eating behavior GO:0042755 6 6 0,000 9,232E-03 0,05043765 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,232E-03 0,05031813 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,232E-03 0,05019918 ! response to copper ion GO:0046688 9 6 0,000 9,232E-03 0,05008078 ! DNA topological change GO:0006265 8 6 0,000 9,232E-03 0,04996295 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,232E-03 0,04984566 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,232E-03 0,04972893 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,232E-03 0,04961274 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,232E-03 0,04949709 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,232E-03 0,04938198 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,232E-03 0,04926741 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,232E-03 0,04915336 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,232E-03 0,04903984 ! gas homeostasis GO:0033483 11 6 0,000 9,232E-03 0,04892685 ! hair follicle maturation GO:0048820 7 6 0,000 9,232E-03 0,04881437 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,232E-03 0,04870241 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,232E-03 0,04859097 ! Schwann cell development GO:0014044 14 6 0,000 9,232E-03 0,04848003 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,232E-03 0,04836959 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,232E-03 0,04825966 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,232E-03 0,04815023 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,232E-03 0,04804129 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,232E-03 0,04793285 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,232E-03 0,04782489 ! histone ubiquitination GO:0016574 7 6 0,000 9,232E-03 0,04771742 ! regulation of meiosis GO:0040020 10 6 0,000 9,232E-03 0,04761043 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,232E-03 0,04750392 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,232E-03 0,04739788 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,232E-03 0,04729232 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,232E-03 0,04718723 ! membrane to membrane docking GO:0022614 12 6 0,000 9,232E-03 0,0470826 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,232E-03 0,04697843 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,232E-03 0,04687473 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,232E-03 0,04677148 ! receptor internalization GO:0031623 9 6 0,000 9,232E-03 0,04666869 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,232E-03 0,04656634 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,232E-03 0,04646445 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,232E-03 0,046363 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,232E-03 0,04626199 ! protein deubiquitination GO:0016579 8 6 0,000 9,232E-03 0,04616142 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,232E-03 0,04606128 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,232E-03 0,04596158 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,232E-03 0,04586232 ! axonal fasciculation GO:0007413 9 6 0,000 9,232E-03 0,04576347 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,232E-03 0,04566506 ! thiamin metabolic process GO:0006772 6 6 0,000 9,232E-03 0,04556706 ! midbrain development GO:0030901 6 6 0,000 9,232E-03 0,04546949 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,232E-03 0,04537233 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,232E-03 0,04527559 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,232E-03 0,04517926 ! progesterone metabolic process GO:0042448 8 6 0,000 9,232E-03 0,04508334 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,232E-03 0,04498782 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,232E-03 0,04489271 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,232E-03 0,044798 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,232E-03 0,04470369 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,232E-03 0,04460977 ! adult feeding behavior GO:0008343 6 6 0,000 9,232E-03 0,04451625 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,232E-03 0,04442312 ! blastocyst growth GO:0001832 15 6 0,000 9,232E-03 0,04433038 ! pigment granule transport GO:0051904 12 6 0,000 9,232E-03 0,04423802 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,232E-03 0,04414605 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,232E-03 0,04405446 ! catecholamine transport GO:0051937 7 6 0,000 9,232E-03 0,04396325 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,232E-03 0,04387242 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,232E-03 0,04378196 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,232E-03 0,04369188 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,232E-03 0,04360216 ! protein prenylation GO:0018342 10 6 0,000 9,232E-03 0,04351281 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,232E-03 0,04342383 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,232E-03 0,04333521 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,232E-03 0,04324695 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,232E-03 0,04315905 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,232E-03 0,0430715 ! in utero embryonic development GO:0001701 147 96 1,000 9,579E-03 0,04460089 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,01035949 0,048135 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,010763 0,04990905 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,010763 0,04980863 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,010763 0,04970861 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,010763 0,049609 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,010763 0,04950978 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,010763 0,04941096 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,010763 0,04931253 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,010763 0,04921449 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,010763 0,04911685 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,010763 0,04901958 ! reproductive behavior GO:0019098 12 7 0,000 0,010763 0,04892271 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,010763 0,04882621 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,010763 0,0487301 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,010763 0,04863436 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,010763 0,048539 ! oligopeptide transport GO:0006857 11 7 0,000 0,010763 0,04844401 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,010763 0,0483494 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,010763 0,04825515 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,010763 0,04816127 ! RNA methylation GO:0001510 11 7 0,000 0,010763 0,04806775 ! pericardium development GO:0060039 8 7 0,000 0,010763 0,04797459 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,010763 0,0478818 ! fibril organization GO:0043206 13 7 0,000 0,010763 0,04778936 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,010763 0,04769728 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,010763 0,04760556 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,010763 0,04751418 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,010763 0,04742316 ! lipoprotein transport GO:0042953 9 7 0,000 0,010763 0,04733249 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,010763 0,04724216 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,010763 0,04715217 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,010763 0,04706253 ! estrogen metabolic process GO:0008210 14 7 0,000 0,010763 0,04697323 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,010763 0,04688426 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,010763 0,04679563 ! chemosensory behavior GO:0007635 9 7 0,000 0,010763 0,04670734 ! microtubule bundle formation GO:0001578 8 7 0,000 0,010763 0,04661938 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,010763 0,04653175 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,010763 0,04644445 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,010763 0,04635747 ! leukocyte degranulation GO:0043299 10 7 0,000 0,010763 0,04627082 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,010763 0,0461845 ! reflex GO:0060004 12 7 0,000 0,010763 0,04609849 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,010763 0,04601281 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,010763 0,04592744 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,010763 0,04584239 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,010763 0,04575765 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,010763 0,04567323 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,010763 0,04558912 ! spinal cord patterning GO:0021511 7 7 0,000 0,010763 0,04550531 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,010763 0,04542182 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,010763 0,04533863 ! adrenal gland development GO:0030325 17 7 0,000 0,010763 0,04525574 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,010763 0,04517316 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,010763 0,04509087 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,010763 0,04500889 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,010763 0,04492721 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,010763 0,04484582 ! endosome organization GO:0007032 10 7 0,000 0,010763 0,04476472 ! thyroid hormone generation GO:0006590 11 7 0,000 0,010763 0,04468392 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,010763 0,04460341 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,010763 0,04452318 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,010763 0,04444325 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,010763 0,0443636 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,010763 0,04428424 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,010763 0,04420516 ! galactose metabolic process GO:0006012 10 7 0,000 0,010763 0,04412636 ! vesicle fusion GO:0006906 15 7 0,000 0,010763 0,04404785 ! intracellular pH reduction GO:0051452 10 7 0,000 0,010763 0,04396961 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,010763 0,04389165 ! organ growth GO:0035265 11 7 0,000 0,010763 0,04381397 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,010763 0,04373656 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,010763 0,04365942 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,010763 0,04358255 ! retinol metabolic process GO:0042572 9 7 0,000 0,010763 0,04350596 ! behavioral fear response GO:0001662 13 7 0,000 0,010763 0,04342963 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,010763 0,04335357 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,010763 0,04327778 ! rRNA modification GO:0000154 12 7 0,000 0,010763 0,04320225 ! protein heterooligomerization GO:0051291 10 7 0,000 0,010763 0,04312699 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,010763 0,04305198 ! response to UV-B GO:0010224 11 7 0,000 0,010763 0,04297724 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,010763 0,04290276 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,010763 0,04282853 ! intermediate filament organization GO:0045109 11 7 0,000 0,010763 0,04275456 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,010763 0,04268085 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,010763 0,04260738 ! fibrinolysis GO:0042730 9 7 0,000 0,010763 0,04253418 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,010763 0,04246122 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,010763 0,04238851 ! B cell lineage commitment GO:0002326 17 7 0,000 0,010763 0,04231605 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,010763 0,04224384 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,010763 0,04217187 ! response to tropane GO:0014073 13 7 0,000 0,010763 0,04210015 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,010763 0,04202868 ! melanosome localization GO:0032400 10 7 0,000 0,010763 0,04195744 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,010763 0,04188645 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,010763 0,04181569 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,010763 0,04174518 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,010763 0,0416749 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,010763 0,04160486 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,010763 0,04153505 ! mast cell activation GO:0045576 9 7 0,000 0,010763 0,04146548 ! multicellular organismal aging GO:0010259 11 7 0,000 0,010763 0,04139614 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,010763 0,04132703 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,010763 0,04125815 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,010763 0,0411895 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,010763 0,04112108 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,010763 0,04105289 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,010763 0,04098492 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,010763 0,04091717 ! T cell lineage commitment GO:0002360 12 7 0,000 0,010763 0,04084965 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,010763 0,04078236 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,010763 0,04071528 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,010763 0,04064842 ! regulation of lipid transport GO:0032368 13 7 0,000 0,010763 0,04058179 ! response to tumor cell GO:0002347 12 7 0,000 0,010763 0,04051537 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,010763 0,04044917 ! neuroblast proliferation GO:0007405 13 7 0,000 0,010763 0,04038318 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,010763 0,04031741 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,010763 0,04025185 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,010763 0,04018651 ! diuresis GO:0030146 12 7 0,000 0,010763 0,04012138 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,010763 0,04005646 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,010763 0,03999175 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,010763 0,03992724 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,010763 0,03986295 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,010763 0,03979886 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,010763 0,03973498 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,010763 0,0396713 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,010763 0,03960782 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,010763 0,03954455 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,010763 0,03948148 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,010763 0,03941862 ! lymph node development GO:0048535 9 7 0,000 0,010763 0,03935595 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,010763 0,03929348 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,010763 0,0392312 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,010763 0,03916913 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,010763 0,03910725 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,010763 0,03904557 ! ATP catabolic process GO:0006200 10 7 0,000 0,010763 0,03898408 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,010763 0,03892278 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,010763 0,03886168 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,010763 0,03880077 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,010763 0,03874005 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,010763 0,03867952 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,010763 0,03861917 ! muscle adaptation GO:0043500 12 7 0,000 0,010763 0,03855902 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,010763 0,03849905 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,010763 0,03843927 ! retina homeostasis GO:0001895 9 7 0,000 0,010763 0,03837967 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,010763 0,03832026 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,010763 0,03826104 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,010763 0,03820199 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,010763 0,03814313 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,010763 0,03808445 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,010763 0,03802595 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,010763 0,03796762 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01229143 0,04329294 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01229143 0,04322674 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01229143 0,04316075 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01229143 0,04309495 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01229143 0,04302936 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01229143 0,04296397 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01229143 0,04289877 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01229143 0,04283377 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01229143 0,04276897 ! phosphate transport GO:0006817 10 8 0,000 0,01229143 0,04270437 ! N-glycan processing GO:0006491 12 8 0,000 0,01229143 0,04263996 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01229143 0,04257574 ! UTP metabolic process GO:0046051 8 8 0,000 0,01229143 0,04251171 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01229143 0,04244788 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01229143 0,04238424 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01229143 0,04232079 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01229143 0,04225753 ! succinate metabolic process GO:0006105 14 8 0,000 0,01229143 0,04219446 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01229143 0,04213158 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01229143 0,04206888 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01229143 0,04200638 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01229143 0,04194405 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01229143 0,04188191 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01229143 0,04181996 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01229143 0,04175818 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01229143 0,04169659 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01229143 0,04163518 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01229143 0,04157396 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01229143 0,04151291 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01229143 0,04145204 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01229143 0,04139135 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01229143 0,04133083 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01229143 0,0412705 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01229143 0,04121034 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01229143 0,04115035 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01229143 0,04109054 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01229143 0,0410309 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01229143 0,04097144 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01229143 0,04091214 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01229143 0,04085302 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01229143 0,04079407 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01229143 0,04073529 ! melanin metabolic process GO:0006582 12 8 0,000 0,01229143 0,04067668 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01229143 0,04061823 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01229143 0,04055996 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01229143 0,04050185 ! macrophage activation GO:0042116 12 8 0,000 0,01229143 0,04044391 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01229143 0,04038613 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01229143 0,04032852 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01229143 0,04027107 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01229143 0,04021378 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01229143 0,04015666 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01229143 0,0400997 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01229143 0,0400429 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01229143 0,03998627 ! ruffle organization GO:0031529 11 8 0,000 0,01229143 0,03992979 ! osteoblast development GO:0002076 13 8 0,000 0,01229143 0,03987347 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01229143 0,03981731 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01229143 0,03976131 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01229143 0,03970546 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01229143 0,03964978 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01229143 0,03959424 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01229143 0,03953887 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01229143 0,03948365 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01229143 0,03942858 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01229143 0,03937366 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01229143 0,0393189 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01229143 0,03926429 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01229143 0,03920983 ! segment specification GO:0007379 10 8 0,000 0,01229143 0,03915553 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01229143 0,03910137 ! cellular extravasation GO:0045123 11 8 0,000 0,01229143 0,03904736 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01229143 0,0389935 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01229143 0,03893979 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01229143 0,03888623 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01229143 0,03883282 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01229143 0,03877955 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01229143 0,03872643 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01229143 0,03867345 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01229143 0,03862062 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01229143 0,03856793 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01229143 0,03851538 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01229143 0,03846298 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01229143 0,03841072 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01229143 0,0383586 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01229143 0,03830663 ! icosanoid secretion GO:0032309 12 8 0,000 0,01229143 0,03825479 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01229143 0,0382031 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01229143 0,03815154 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01229143 0,03810012 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01229143 0,03804884 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01229143 0,0379977 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01229143 0,0379467 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01229143 0,03789583 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01229143 0,0378451 ! sterol catabolic process GO:0016127 9 8 0,000 0,01229143 0,03779451 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01229143 0,03774405 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01229143 0,03769372 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01229143 0,03764353 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01229143 0,03759347 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01229143 0,03754355 ! prophase GO:0051324 11 8 0,000 0,01229143 0,03749375 ! S phase GO:0051320 8 8 0,000 0,01229143 0,03744409 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01229143 0,03739456 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01229143 0,03734517 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01229143 0,0372959 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01229143 0,03724676 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01229143 0,03719775 ! hormone catabolic process GO:0042447 13 8 0,000 0,01229143 0,03714887 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01229143 0,03710012 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01229143 0,03705149 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01229143 0,037003 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01229143 0,03695463 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01229143 0,03690638 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01229143 0,03685827 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01229143 0,03681027 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01229143 0,03676241 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01229143 0,03671466 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01229143 0,03666704 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01229143 0,03661955 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01229143 0,03657217 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01229143 0,03652492 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01229143 0,03647779 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01229143 0,03643079 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01229143 0,0363839 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01381759 0,04084892 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01381759 0,04079648 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01381759 0,04074418 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01381759 0,04069201 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01381759 0,04063997 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01381759 0,04058807 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01381759 0,0405363 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01381759 0,04048466 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01381759 0,04043316 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01381759 0,04038178 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01381759 0,04033053 ! GTP metabolic process GO:0046039 9 9 0,000 0,01381759 0,04027942 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01381759 0,04022843 ! social behavior GO:0035176 14 9 0,000 0,01381759 0,04017757 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01381759 0,04012684 ! artery development GO:0060840 19 9 0,000 0,01381759 0,04007624 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01381759 0,04002577 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01381759 0,03997542 ! response to pain GO:0048265 16 9 0,000 0,01381759 0,0399252 ! protein complex disassembly GO:0043241 17 9 0,000 0,01381759 0,03987511 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01381759 0,03982514 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01381759 0,03977529 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01381759 0,03972557 ! lung alveolus development GO:0048286 17 9 0,000 0,01381759 0,03967598 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01381759 0,03962651 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01381759 0,03957716 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01381759 0,03952794 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01381759 0,03947883 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01381759 0,03942985 ! protein targeting to ER GO:0045047 19 9 0,000 0,01381759 0,03938099 ! T cell selection GO:0045058 18 9 0,000 0,01381759 0,03933225 ! endoderm development GO:0007492 12 9 0,000 0,01381759 0,03928363 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01381759 0,03923514 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01381759 0,03918676 ! arginine catabolic process GO:0006527 10 9 0,000 0,01381759 0,0391385 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01381759 0,03909036 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01381759 0,03904233 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01381759 0,03899443 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01381759 0,03894664 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01381759 0,03889897 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01381759 0,03885142 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01381759 0,03880398 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01381759 0,03875666 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01381759 0,03870945 ! mannose metabolic process GO:0006013 9 9 0,000 0,01381759 0,03866236 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01381759 0,03861538 ! receptor clustering GO:0043113 15 9 0,000 0,01381759 0,03856852 ! epithelial cell development GO:0002064 10 9 0,000 0,01381759 0,03852177 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01381759 0,03847513 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01381759 0,03842861 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01381759 0,0383822 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01381759 0,0383359 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01381759 0,03828971 ! motor axon guidance GO:0008045 14 9 0,000 0,01381759 0,03824363 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01381759 0,03819767 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01381759 0,03815181 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01381759 0,03810607 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01381759 0,03806043 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01381759 0,0380149 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01381759 0,03796949 ! DNA ligation GO:0006266 14 9 0,000 0,01381759 0,03792418 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01381759 0,03787897 ! response to amine stimulus GO:0014075 13 9 0,000 0,01381759 0,03783388 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01381759 0,03778889 ! erythrocyte development GO:0048821 11 9 0,000 0,01381759 0,03774401 ! renal water homeostasis GO:0003091 14 9 0,000 0,01381759 0,03769924 ! postreplication repair GO:0006301 11 9 0,000 0,01381759 0,03765457 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01381759 0,03761001 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01381759 0,03756556 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01381759 0,0375212 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01381759 0,03747696 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01381759 0,03743281 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01381759 0,03738878 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01381759 0,03734484 ! acid secretion GO:0046717 14 9 0,000 0,01381759 0,03730101 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01381759 0,03725728 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01381759 0,03721365 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01381759 0,03717013 ! purine base metabolic process GO:0006144 18 9 0,000 0,01381759 0,03712671 ! oocyte differentiation GO:0009994 12 9 0,000 0,01381759 0,03708338 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01381759 0,03704016 ! spleen development GO:0048536 15 9 0,000 0,01381759 0,03699704 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01381759 0,03695402 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01381759 0,0369111 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01381759 0,03686828 ! detection of calcium ion GO:0005513 13 9 0,000 0,01381759 0,03682556 ! blastocyst formation GO:0001825 12 9 0,000 0,01381759 0,03678294 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01381759 0,03674042 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01381759 0,03669799 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01381759 0,03665566 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01381759 0,03661343 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01381759 0,0365713 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01381759 0,03652926 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01381759 0,03648732 ! prepulse inhibition GO:0060134 14 9 0,000 0,01381759 0,03644548 ! embryonic placenta development GO:0001892 12 9 0,000 0,01381759 0,03640373 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01381759 0,03636208 ! insulin secretion GO:0030073 17 9 0,000 0,01381759 0,03632053 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01381759 0,03627906 ! response to nicotine GO:0035094 16 9 0,000 0,01381759 0,0362377 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01381759 0,03619642 ! nucleus localization GO:0051647 15 9 0,000 0,01381759 0,03615524 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01381759 0,03611416 ! localization within membrane GO:0051668 15 9 0,000 0,01381759 0,03607317 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01534148 0,04000613 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01534148 0,03996082 ! neuron fate specification GO:0048665 11 10 0,000 0,01534148 0,03991562 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01534148 0,03987052 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01534148 0,03982551 ! thyroid gland development GO:0030878 19 10 0,000 0,01534148 0,03978062 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01534148 0,03973582 ! synapsis GO:0007129 13 10 0,000 0,01534148 0,03969112 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01534148 0,03964652 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01534148 0,03960203 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01534148 0,03955763 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01534148 0,03951333 ! sulfate transport GO:0008272 12 10 0,000 0,01534148 0,03946913 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01534148 0,03942503 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01534148 0,03938103 ! androgen metabolic process GO:0008209 13 10 0,000 0,01534148 0,03933713 ! phospholipid efflux GO:0033700 16 10 0,000 0,01534148 0,03929333 ! hippocampus development GO:0021766 19 10 0,000 0,01534148 0,03924962 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01534148 0,03920601 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01534148 0,03916249 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01534148 0,03911908 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01534148 0,03907575 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01534148 0,03903253 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01534148 0,0389894 ! pathogenesis GO:0009405 13 10 0,000 0,01534148 0,03894636 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01534148 0,03890342 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01534148 0,03886058 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01534148 0,03881783 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01534148 0,03877517 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01534148 0,03873261 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01534148 0,03869014 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01534148 0,03864776 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01534148 0,03860548 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01534148 0,03856329 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01534148 0,03852119 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01534148 0,03847918 ! response to X-ray GO:0010165 16 10 0,000 0,01534148 0,03843726 ! B cell proliferation GO:0042100 14 10 0,000 0,01534148 0,03839544 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01534148 0,0383537 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01534148 0,03831206 ! forebrain cell migration GO:0021885 17 10 0,000 0,01534148 0,03827051 ! lipid digestion GO:0044241 15 10 0,000 0,01534148 0,03822904 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01534148 0,03818767 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01534148 0,03814639 ! UV protection GO:0009650 14 10 0,000 0,01534148 0,03810519 ! entry into host cell GO:0030260 20 10 0,000 0,01534148 0,03806408 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01534148 0,03802307 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01534148 0,03798214 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01534148 0,0379413 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01534148 0,03790054 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01534148 0,03785988 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01534148 0,0378193 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01534148 0,03777881 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01534148 0,0377384 ! regulation of organ growth GO:0046620 11 10 0,000 0,01534148 0,03769808 ! response to dsRNA GO:0043331 18 10 0,000 0,01534148 0,03765785 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01534148 0,0376177 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01534148 0,03757764 ! embryonic axis specification GO:0000578 12 10 0,000 0,01534148 0,03753767 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01534148 0,03749778 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01534148 0,03745797 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01534148 0,03741825 ! cranial nerve development GO:0021545 12 10 0,000 0,01534148 0,03737861 ! fucose catabolic process GO:0019317 16 10 0,000 0,01534148 0,03733905 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01534148 0,03729958 GO:0006305|DNA alkylation, ! protein sumoylation GO:0016925 12 10 0,000 0,01534148 0,0372602 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01534148 0,03722089 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01534148 0,03718167 ! zymogen activation GO:0031638 14 10 0,000 0,01534148 0,03714253 ! salivary gland development GO:0007431 22 10 0,000 0,01534148 0,03710348 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01534148 0,0370645 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01534148 0,03702561 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01534148 0,0369868 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01534148 0,03694807 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01534148 0,03690942 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01534148 0,03687085 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01534148 0,03683237 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01534148 0,03679396 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01534148 0,03675563 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01534148 0,03671738 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01534148 0,03667922 ! detection of bacterium GO:0016045 10 10 0,000 0,01534148 0,03664113 ! embryonic gut development GO:0048566 11 10 0,000 0,01534148 0,03660312 ! activation of innate immune response GO:0002218 10 10 0,000 0,01534148 0,03656519 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01534148 0,03652734 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01534148 0,03648956 ! developmental induction GO:0031128 13 10 0,000 0,01534148 0,03645187 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01534148 0,03641425 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01534148 0,03637671 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01534148 0,03633924 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01534148 0,03630186 ! rRNA transcription GO:0009303 17 11 0,000 0,0168631 0,03986139 ! respiratory burst GO:0045730 14 11 0,000 0,0168631 0,03982047 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0168631 0,03977963 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0168631 0,03973887 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0168631 0,0396982 ! virus-host interaction GO:0019048 17 11 0,000 0,0168631 0,0396576 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,0168631 0,0396171 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,0168631 0,03957667 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,0168631 0,03953633 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0168631 0,03949607 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0168631 0,03945589 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,0168631 0,03941579 ! mating GO:0007618 14 11 0,000 0,0168631 0,03937577 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,0168631 0,03933584 ! T cell proliferation GO:0042098 20 11 0,000 0,0168631 0,03929598 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0168631 0,03925621 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0168631 0,03921652 ! bone resorption GO:0045453 16 11 0,000 0,0168631 0,03917691 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0168631 0,03913737 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0168631 0,03909792 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0168631 0,03905855 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0168631 0,03901925 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0168631 0,03898004 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0168631 0,0389409 ! syncytium formation GO:0006949 15 11 0,000 0,0168631 0,03890184 ! plasma membrane organization GO:0007009 18 11 0,000 0,0168631 0,03886286 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0168631 0,03882396 ! focal adhesion formation GO:0048041 24 11 0,000 0,0168631 0,03878514 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0168631 0,03874639 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0168631 0,03870772 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,0168631 0,03866913 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0168631 0,03863061 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0168631 0,03859218 ! adult heart development GO:0007512 11 11 0,000 0,0168631 0,03855381 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0168631 0,03851553 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,0168631 0,03847732 ! temperature homeostasis GO:0001659 16 11 0,000 0,0168631 0,03843918 ! L-glutamate transport GO:0015813 16 11 0,000 0,0168631 0,03840113 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0168631 0,03836314 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0168631 0,03832523 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0168631 0,0382874 ! stem cell development GO:0048864 29 11 0,000 0,0168631 0,03824964 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0168631 0,03821196 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0168631 0,03817435 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0168631 0,03813681 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0168631 0,03809935 ! vasoconstriction GO:0042310 15 11 0,000 0,0168631 0,03806196 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0168631 0,03802464 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0168631 0,0379874 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0168631 0,03795023 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0168631 0,03791313 ! ribosome assembly GO:0042255 13 11 0,000 0,0168631 0,03787611 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,0168631 0,03783916 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,0168631 0,03780228 ! chromatin silencing GO:0006342 19 11 0,000 0,0168631 0,03776547 ! nucleosome positioning GO:0016584 13 11 0,000 0,0168631 0,03772873 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0168631 0,03769207 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0168631 0,03765547 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0168631 0,03761895 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0168631 0,0375825 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0168631 0,03754612 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0168631 0,0375098 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0168631 0,03747356 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0168631 0,03743739 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0168631 0,03740129 ! male genitalia development GO:0030539 13 11 0,000 0,0168631 0,03736526 ! cholesterol efflux GO:0033344 19 11 0,000 0,0168631 0,03732929 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0168631 0,0372934 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0168631 0,03725758 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0168631 0,03722182 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0168631 0,03718613 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0168631 0,03715051 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0168631 0,03711496 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,0168631 0,03707948 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,0168631 0,03704407 ! lysogeny GO:0030069 18 11 0,000 0,0168631 0,03700872 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0168631 0,03697344 ! acrosome reaction GO:0007340 13 11 0,000 0,0168631 0,03693823 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,0168631 0,03690308 ! lactation GO:0007595 20 12 0,000 0,01838246 0,04018979 ! reproductive cellular process GO:0048610 14 12 0,000 0,01838246 0,04015162 ! tRNA modification GO:0006400 14 12 0,000 0,01838246 0,04011353 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01838246 0,04007551 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01838246 0,04003756 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01838246 0,03999968 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01838246 0,03996187 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01838246 0,03992414 ! non-recombinational repair GO:0000726 19 12 0,000 0,01838246 0,03988647 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01838246 0,03984888 ! peroxisomal transport GO:0043574 21 12 0,000 0,01838246 0,03981136 ! cartilage condensation GO:0001502 18 12 0,000 0,01838246 0,0397739 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01838246 0,03973652 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01838246 0,03969921 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01838246 0,03966197 ! heart looping GO:0001947 15 12 0,000 0,01838246 0,0396248 ! palate development GO:0060021 15 12 0,000 0,01838246 0,0395877 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01838246 0,03955066 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01838246 0,0395137 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01838246 0,03947681 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01838246 0,03943998 ! arginine metabolic process GO:0006525 13 12 0,000 0,01838246 0,03940322 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01838246 0,03936654 ! methionine metabolic process GO:0006555 13 12 0,000 0,01838246 0,03932992 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01838246 0,03929336 ! Golgi organization GO:0007030 18 12 0,000 0,01838246 0,03925688 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01838246 0,03922046 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01838246 0,03918411 ! monoamine transport GO:0015844 13 12 0,000 0,01838246 0,03914783 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01838246 0,03911162 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01838246 0,03907547 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01838246 0,03903939 ! L-amino acid transport GO:0015807 20 12 0,000 0,01838246 0,03900338 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01838246 0,03896743 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01838246 0,03893155 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01838246 0,03889573 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01838246 0,03885998 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01838246 0,0388243 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01838246 0,03878868 ! cerebellum development GO:0021549 13 12 0,000 0,01838246 0,03875312 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01838246 0,03871764 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01838246 0,03868221 ! histone acetylation GO:0016573 23 12 0,000 0,01838246 0,03864685 ! histone methylation GO:0016571 15 12 0,000 0,01838246 0,03861156 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01838246 0,03857633 ! gland morphogenesis GO:0022612 23 12 0,000 0,01838246 0,03854117 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01838246 0,03850606 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01838246 0,03847103 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01838246 0,03843605 ! response to gamma radiation GO:0010332 20 12 0,000 0,01838246 0,03840114 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01838246 0,0383663 ! intestinal absorption GO:0050892 19 12 0,000 0,01838246 0,03833151 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01838246 0,03829679 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01838246 0,03826214 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01838246 0,03822754 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01838246 0,03819301 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01838246 0,03815854 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01838246 0,03812413 ! microspike assembly GO:0030035 23 12 0,000 0,01838246 0,03808978 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01838246 0,0380555 ! response to cold GO:0009409 14 12 0,000 0,01838246 0,03802128 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01989956 0,04112218 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01989956 0,04108526 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01989956 0,04104841 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01989956 0,04101163 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01989956 0,04097492 ! water transport GO:0006833 17 13 0,000 0,01989956 0,04093827 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01989956 0,04090168 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01989956 0,04086516 ! lipid localization GO:0010876 24 13 0,000 0,01989956 0,04082871 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01989956 0,04079232 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01989956 0,04075599 ! organelle fusion GO:0048284 28 13 0,000 0,01989956 0,04071973 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01989956 0,04068354 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01989956 0,04064741 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01989956 0,04061134 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01989956 0,04057534 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01989956 0,0405394 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01989956 0,04050352 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01989956 0,04046771 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01989956 0,04043196 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01989956 0,04039628 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01989956 0,04036065 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01989956 0,04032509 ! NAD metabolic process GO:0019674 21 13 0,000 0,01989956 0,0402896 ! exocrine system development GO:0035272 27 13 0,000 0,01989956 0,04025416 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01989956 0,04021879 ! bone mineralization GO:0030282 15 13 0,000 0,01989956 0,04018348 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01989956 0,04014823 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01989956 0,04011304 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01989956 0,04007792 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01989956 0,04004285 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01989956 0,04000785 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01989956 0,03997291 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01989956 0,03993803 ! genitalia development GO:0048806 15 13 0,000 0,01989956 0,03990321 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01989956 0,03986845 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01989956 0,03983375 ! cellular pigmentation GO:0033059 24 13 0,000 0,01989956 0,03979911 ! tissue regeneration GO:0042246 21 13 0,000 0,01989956 0,03976454 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01989956 0,03973002 ! cofactor transport GO:0051181 19 13 0,000 0,01989956 0,03969556 ! NADP metabolic process GO:0006739 18 13 0,000 0,01989956 0,03966116 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01989956 0,03962682 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01989956 0,03959254 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01989956 0,03955832 ! gas transport GO:0015669 18 13 0,000 0,01989956 0,03952416 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01989956 0,03949006 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01989956 0,03945602 ! regulation of axon extension GO:0030516 23 13 0,000 0,01989956 0,03942203 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01989956 0,03938811 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01989956 0,03935424 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01989956 0,03932043 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01989956 0,03928668 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01989956 0,03925299 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0214144 0,04220489 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0214144 0,04216876 ! superoxide anion generation GO:0042554 18 14 0,000 0,0214144 0,04213269 ! neuron maturation GO:0042551 21 14 0,000 0,0214144 0,04209667 ! regulation of S phase GO:0033261 18 14 0,000 0,0214144 0,04206073 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0214144 0,04202484 ! myotube differentiation GO:0014902 21 14 0,000 0,0214144 0,04198901 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,0214144 0,04195324 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0214144 0,04191754 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0214144 0,0418819 ! inositol metabolic process GO:0006020 20 14 0,000 0,0214144 0,04184631 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0214144 0,04181079 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0214144 0,04177533 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0214144 0,04173992 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0214144 0,04170458 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0214144 0,0416693 ! response to cAMP GO:0051591 19 14 0,000 0,0214144 0,04163407 ! limbic system development GO:0021761 25 14 0,000 0,0214144 0,04159891 ! startle response GO:0001964 21 14 0,000 0,0214144 0,04156381 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0214144 0,04152876 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0214144 0,04149377 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0214144 0,04145885 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0214144 0,04142398 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0214144 0,04138917 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0214144 0,04135442 ! glycine metabolic process GO:0006544 22 14 0,000 0,0214144 0,04131972 ! pituitary gland development GO:0021983 23 14 0,000 0,0214144 0,04128509 ! cellular response to starvation GO:0009267 21 14 0,000 0,0214144 0,04125051 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0214144 0,04121599 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0214144 0,04118153 ! regulation of heart rate GO:0002027 23 14 0,000 0,0214144 0,04114713 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0214144 0,04111278 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0214144 0,04107849 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0214144 0,04104426 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0214144 0,04101008 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0214144 0,04097596 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0214144 0,0409419 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0214144 0,0409079 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0214144 0,04087395 ! axon cargo transport GO:0008088 27 14 0,000 0,0214144 0,04084006 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0214144 0,04080622 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0214144 0,04077244 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0214144 0,04073872 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0214144 0,04070505 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0214144 0,04067144 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0214144 0,04063788 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0214144 0,04060438 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0214144 0,04057093 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0214144 0,04053754 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0214144 0,0405042 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0214144 0,04047092 ! muscle maintenance GO:0046716 19 14 0,000 0,0214144 0,04043769 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0214144 0,04040452 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0214144 0,0403714 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0214144 0,04033834 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0214144 0,04030533 ! cell killing GO:0001906 20 14 0,000 0,0214144 0,04027237 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,0214144 0,04023947 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0214144 0,04020662 ! cilium assembly GO:0042384 20 14 0,000 0,0214144 0,04017382 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0214144 0,04014108 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02292698 0,04294141 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02292698 0,04290647 ! metencephalon development GO:0022037 19 15 0,000 0,02292698 0,04287159 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02292698 0,04283676 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02292698 0,04280199 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02292698 0,04276728 ! skin development GO:0043588 25 15 0,000 0,02292698 0,04273262 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02292698 0,04269802 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02292698 0,04266347 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02292698 0,04262898 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02292698 0,04259455 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02292698 0,04256017 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02292698 0,04252585 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02292698 0,04249158 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02292698 0,04245737 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02292698 0,04242321 ! adult walking behavior GO:0007628 25 15 0,000 0,02292698 0,04238911 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02292698 0,04235506 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02292698 0,04232107 ! myoblast differentiation GO:0045445 27 15 0,000 0,02292698 0,04228713 ! centrosome cycle GO:0007098 16 15 0,000 0,02292698 0,04225325 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02292698 0,04221942 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02292698 0,04218564 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02292698 0,04215192 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02292698 0,04211825 ! cerebral cortex development GO:0021987 29 15 0,000 0,02292698 0,04208464 ! response to osmotic stress GO:0006970 22 15 0,000 0,02292698 0,04205108 ! vesicle coating GO:0006901 25 15 0,000 0,02292698 0,04201757 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02292698 0,04198412 ! DNA integration GO:0015074 22 15 0,000 0,02292698 0,04195072 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02292698 0,04191737 ! peptide secretion GO:0002790 27 15 0,000 0,02292698 0,04188408 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02292698 0,04185083 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02292698 0,04181765 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02292698 0,04178451 ! neuron recognition GO:0008038 22 15 0,000 0,02292698 0,04175143 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02292698 0,0417184 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02292698 0,04168542 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02292698 0,04165249 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02292698 0,04161961 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02292698 0,04158679 ! biomineral formation GO:0031214 18 15 0,000 0,02292698 0,04155402 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02292698 0,0415213 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02292698 0,04148863 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02292698 0,04145602 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02292698 0,04142345 ! organic cation transport GO:0015695 19 15 0,000 0,02292698 0,04139094 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02292698 0,04135847 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02292698 0,04132606 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02292698 0,0412937 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02292698 0,04126139 ! defense response to virus GO:0051607 27 15 0,000 0,02292698 0,04122913 ! peptide hormone processing GO:0016486 19 15 0,000 0,02292698 0,04119692 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02292698 0,04116476 ! protein secretion GO:0009306 27 16 0,000 0,02443731 0,04384229 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02443731 0,04380812 ! hormone secretion GO:0046879 25 16 0,000 0,02443731 0,043774 ! bone remodeling GO:0046849 24 16 0,000 0,02443731 0,04373993 ! endothelial cell migration GO:0043542 22 16 0,000 0,02443731 0,04370592 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02443731 0,04367196 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02443731 0,04363806 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02443731 0,0436042 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02443731 0,0435704 ! glial cell development GO:0021782 24 16 0,000 0,02443731 0,04353665 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02443731 0,04350295 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02443731 0,04346931 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02443731 0,04343572 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02443731 0,04340217 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02443731 0,04336868 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02443731 0,04333525 ! fructose metabolic process GO:0006000 20 16 0,000 0,02443731 0,04330186 ! regulation of protein binding GO:0043393 27 16 0,000 0,02443731 0,04326853 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02443731 0,04323524 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02443731 0,04320201 ! protein export from nucleus GO:0006611 24 16 0,000 0,02443731 0,04316883 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02443731 0,0431357 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02443731 0,04310262 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02443731 0,04306959 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02443731 0,04303661 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02443731 0,04300368 ! diencephalon development GO:0021536 25 16 0,000 0,02443731 0,04297081 ! oogenesis GO:0048477 23 16 0,000 0,02443731 0,04293798 ! neural crest cell migration GO:0001755 24 16 0,000 0,02443731 0,0429052 ! G1 phase GO:0051318 27 16 0,000 0,02443731 0,04287248 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02443731 0,0428398 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02443731 0,04280717 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02443731 0,04277459 ! steroid catabolic process GO:0006706 22 16 0,000 0,02443731 0,04274207 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02443731 0,04270959 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02443731 0,04267716 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02443731 0,04264478 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02443731 0,04261245 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02443731 0,04258016 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02443731 0,04254793 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02443731 0,04251575 ! nerve development GO:0021675 18 16 0,000 0,02443731 0,04248361 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02443731 0,04245152 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02443731 0,04241948 ! negative regulation of translation GO:0017148 22 16 0,000 0,02443731 0,04238749 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0259454 0,04496941 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0259454 0,04493555 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0259454 0,04490174 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0259454 0,04486798 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0259454 0,04483427 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0259454 0,04480061 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0259454 0,044767 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0259454 0,04473344 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0259454 0,04469993 ! signal complex assembly GO:0007172 29 17 0,000 0,0259454 0,04466647 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0259454 0,04463307 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0259454 0,04459971 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,0259454 0,0445664 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0259454 0,04453314 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0259454 0,04449993 ! memory GO:0007613 25 17 0,000 0,0259454 0,04446677 ! keratinization GO:0031424 17 17 0,000 0,0259454 0,04443366 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0259454 0,0444006 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,0259454 0,04436759 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0259454 0,04433463 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0259454 0,04430171 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0259454 0,04426885 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0259454 0,04423603 ! vacuolar transport GO:0007034 24 17 0,000 0,0259454 0,04420327 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0259454 0,04417055 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,0259454 0,04413788 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0259454 0,04410525 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0259454 0,04407268 ! membrane budding GO:0006900 29 17 0,000 0,0259454 0,04404015 ! heme metabolic process GO:0042168 27 17 0,000 0,0259454 0,04400768 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0259454 0,04397525 ! neuromuscular junction development GO:0007528 23 17 0,000 0,0259454 0,04394286 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0259454 0,04391053 ! body fluid secretion GO:0007589 27 17 0,000 0,0259454 0,04387824 ! stem cell differentiation GO:0048863 36 17 0,000 0,0259454 0,043846 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0259454 0,04381381 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,0259454 0,04378166 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0259454 0,04374957 ! sensory perception of pain GO:0019233 23 17 0,000 0,0259454 0,04371752 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0259454 0,04368551 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0259454 0,04365355 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,0259454 0,04362164 ! synaptogenesis GO:0007416 24 17 0,000 0,0259454 0,04358978 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,0259454 0,04355796 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0259454 0,04352619 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0259454 0,04349447 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0259454 0,04346279 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0259454 0,04343116 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,0259454 0,04339957 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0259454 0,04336803 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,0259454 0,04333653 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0259454 0,04330509 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0259454 0,04327368 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02745123 0,04575206 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02745123 0,04571893 ! positive regulation of translation GO:0045727 28 18 0,000 0,02745123 0,04568584 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02745123 0,04565281 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02745123 0,04561982 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02745123 0,04558689 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02745123 0,045554 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02745123 0,04552115 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02745123 0,04548836 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02745123 0,04545561 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02745123 0,0454229 ! axis specification GO:0009798 26 18 0,000 0,02745123 0,04539025 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02745123 0,04535764 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02745123 0,04532508 ! pancreas development GO:0031016 26 18 0,000 0,02745123 0,04529257 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02745123 0,0452601 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02745123 0,04522768 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02745123 0,0451953 ! response to retinoic acid GO:0032526 25 18 0,000 0,02745123 0,04516297 ! pigmentation during development GO:0048066 31 18 0,000 0,02745123 0,04513069 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02745123 0,04509846 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02745123 0,04506627 ! fucose metabolic process GO:0006004 26 18 0,000 0,02745123 0,04503412 ! response to fungus GO:0009620 19 18 0,000 0,02745123 0,04500202 ! peptide cross-linking GO:0018149 31 18 0,000 0,02745123 0,04496997 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02745123 0,04493796 ! heart process GO:0003015 27 18 0,000 0,02745123 0,044906 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02745123 0,04487409 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02745123 0,04484221 ! visual learning GO:0008542 35 18 0,000 0,02745123 0,04481039 ! somitogenesis GO:0001756 24 18 0,000 0,02745123 0,04477861 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02745123 0,04474687 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02745123 0,04471518 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02745123 0,04468354 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02745123 0,04465194 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02745123 0,04462038 ! vitamin transport GO:0051180 24 18 0,000 0,02745123 0,04458887 ! hormone transport GO:0009914 27 18 0,000 0,02745123 0,0445574 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02745123 0,04452598 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02745123 0,0444946 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02745123 0,04446327 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02745123 0,04443198 ! cell-cell recognition GO:0009988 20 18 0,000 0,02745123 0,04440073 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02745123 0,04436953 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02745123 0,04433837 ! regulation of glucose import GO:0046324 21 18 0,000 0,02745123 0,04430725 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02745123 0,04427618 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02745123 0,04424516 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02745123 0,04421417 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02745123 0,04418323 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02895483 0,04657071 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02895483 0,04653816 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02895483 0,04650566 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02895483 0,04647321 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02895483 0,0464408 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02895483 0,04640844 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02895483 0,04637612 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02895483 0,04634385 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02895483 0,04631162 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02895483 0,04627944 ! regeneration GO:0031099 32 19 0,000 0,02895483 0,0462473 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02895483 0,04621521 ! response to alkaloid GO:0043279 32 19 0,000 0,02895483 0,04618316 ! sensory perception of taste GO:0050909 23 19 0,000 0,02895483 0,04615115 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02895483 0,04611919 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02895483 0,04608727 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02895483 0,0460554 ! peroxisome organization GO:0007031 29 19 0,000 0,02895483 0,04602357 ! digestive system process GO:0022600 30 19 0,000 0,02895483 0,04599179 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02895483 0,04596005 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02895483 0,04592835 ! response to vitamin A GO:0033189 26 19 0,000 0,02895483 0,0458967 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02895483 0,04586509 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02895483 0,04583352 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02895483 0,045802 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02895483 0,04577052 ! response to starvation GO:0042594 30 19 0,000 0,02895483 0,04573909 ! sex determination GO:0007530 29 19 0,000 0,02895483 0,04570769 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02895483 0,04567634 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02895483 0,04564504 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02895483 0,04561377 ! cytolysis GO:0019835 20 19 0,000 0,02895483 0,04558255 ! renal system process GO:0003014 35 19 0,000 0,02895483 0,04555138 ! vasodilation GO:0042311 33 19 0,000 0,02895483 0,04552024 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02895483 0,04548915 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02895483 0,0454581 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02895483 0,04542709 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02895483 0,04539612 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02895483 0,0453652 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02895483 0,04533432 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02895483 0,04530348 ! sarcomere organization GO:0045214 23 19 0,000 0,02895483 0,04527268 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02895483 0,04524192 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02895483 0,04521121 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02895483 0,04518054 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02895483 0,04514991 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02895483 0,04511932 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02895483 0,04508877 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02895483 0,04505826 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02895483 0,0450278 ! protein stabilization GO:0050821 26 19 0,000 0,02895483 0,04499737 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03045619 0,04729861 ! iron ion transport GO:0006826 37 20 0,000 0,03045619 0,04726669 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03045619 0,04723482 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03045619 0,04720299 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03045619 0,0471712 ! response to vitamin GO:0033273 29 20 0,000 0,03045619 0,04713946 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03045619 0,04710776 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03045619 0,0470761 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03045619 0,04704448 ! spinal cord development GO:0021510 31 20 0,000 0,03045619 0,04701291 ! response to ethanol GO:0045471 37 20 0,000 0,03045619 0,04698138 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03045619 0,04694989 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03045619 0,04691844 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03045619 0,04688704 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03045619 0,04685568 ! chromosome condensation GO:0030261 31 20 0,000 0,03045619 0,04682435 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03045619 0,04679308 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03045619 0,04676184 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03045619 0,04673064 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03045619 0,04669949 ! pallium development GO:0021543 38 20 0,000 0,03045619 0,04666838 ! DNA modification GO:0006304 28 20 0,000 0,03045619 0,04663731 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03045619 0,04660628 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03045619 0,04657529 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03045619 0,04654434 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03045619 0,04651344 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03045619 0,04648257 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03045619 0,04645175 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03045619 0,04642096 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03045619 0,04639022 ! alditol metabolic process GO:0019400 24 20 0,000 0,03045619 0,04635952 ! actin filament-based movement GO:0030048 34 20 0,000 0,03045619 0,04632886 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03195531 0,04857714 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03195531 0,04854506 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03195531 0,04851301 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03195531 0,04848101 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03195531 0,04844906 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03195531 0,04841714 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03195531 0,04838526 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03195531 0,04835343 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03195531 0,04832164 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03195531 0,04828989 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03195531 0,04825819 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03195531 0,04822652 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03195531 0,0481949 ! vesicle docking GO:0048278 27 21 0,000 0,03195531 0,04816331 ! phototransduction GO:0007602 25 21 0,000 0,03195531 0,04813177 ! dendrite development GO:0016358 35 21 0,000 0,03195531 0,04810027 ! visual behavior GO:0007632 39 21 0,000 0,03195531 0,04806881 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03195531 0,0480374 ! ovarian follicle development GO:0001541 30 21 0,000 0,03195531 0,04800602 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03195531 0,04797468 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03195531 0,04794339 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03195531 0,04791214 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03195531 0,04788092 ! cell aging GO:0007569 32 21 0,000 0,03195531 0,04784975 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03195531 0,04781862 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03195531 0,04778753 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03195531 0,04775648 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03195531 0,04772547 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03195531 0,0476945 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03195531 0,04766356 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03195531 0,04763267 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03195531 0,04760182 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03195531 0,04757101 ! fatty acid transport GO:0015908 30 21 0,000 0,03195531 0,04754024 ! immunoglobulin production GO:0002377 33 21 0,000 0,03195531 0,04750951 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03195531 0,04747882 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03195531 0,04744817 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03195531 0,04741756 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03195531 0,04738699 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03195531 0,04735645 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03195531 0,04732596 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03195531 0,04729551 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03195531 0,04726509 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03195531 0,04723472 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03195531 0,04720438 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03195531 0,04717408 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03195531 0,04714382 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03195531 0,0471136 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03195531 0,04708342 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,0334522 0,0492574 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,0334522 0,04922589 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0334522 0,04919442 ! viral genome replication GO:0019079 29 22 0,000 0,0334522 0,04916298 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0334522 0,04913159 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0334522 0,04910023 ! molting cycle process GO:0022404 40 22 0,000 0,0334522 0,04906892 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,0334522 0,04903765 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0334522 0,04900641 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,0334522 0,04897522 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0334522 0,04894406 ! vasculogenesis GO:0001570 33 22 0,000 0,0334522 0,04891295 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,0334522 0,04888187 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,0334522 0,04885084 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,0334522 0,04881984 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0334522 0,04878888 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,0334522 0,04875796 ! lysosome organization GO:0007040 37 22 0,000 0,0334522 0,04872708 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0334522 0,04869624 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,0334522 0,04866544 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0334522 0,04863468 ! regulation of behavior GO:0050795 38 22 0,000 0,0334522 0,04860396 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0334522 0,04857327 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0334522 0,04854263 ! membrane depolarization GO:0051899 35 22 0,000 0,0334522 0,04851202 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0334522 0,04848145 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,0334522 0,04845092 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,0334522 0,04842043 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0334522 0,04838998 ! blastocyst development GO:0001824 37 22 0,000 0,0334522 0,04835956 ! neural tube closure GO:0001843 33 22 0,000 0,0334522 0,04832919 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0334522 0,04829885 ! protein tetramerization GO:0051262 39 22 0,000 0,0334522 0,04826855 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03494686 0,0503936 ! neuron fate commitment GO:0048663 32 23 0,000 0,03494686 0,05036202 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03494686 0,05033049 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03494686 0,05029899 ! myelination GO:0042552 35 23 0,000 0,03494686 0,05026753 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03494686 0,05023612 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03494686 0,05020474 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03494686 0,0501734 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03494686 0,0501421 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03494686 0,05011084 ! vesicle targeting GO:0006903 32 23 0,000 0,03494686 0,05007962 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03494686 0,05004844 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03494686 0,05001729 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03494686 0,04998619 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03494686 0,04995512 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03494686 0,04992409 ! interaction with host GO:0051701 37 23 0,000 0,03494686 0,0498931 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03494686 0,04986215 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03494686 0,04983124 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03494686 0,04980036 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03494686 0,04976953 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03494686 0,04973873 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03494686 0,04970797 ! cell fate determination GO:0001709 45 23 0,000 0,03494686 0,04967725 ! pentose metabolic process GO:0019321 31 23 0,000 0,03494686 0,04964656 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03494686 0,04961592 ! spermatid development GO:0007286 33 23 0,000 0,03494686 0,04958531 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03494686 0,04955474 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03494686 0,04952421 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03494686 0,04949371 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03494686 0,04946325 ! telomere organization GO:0032200 32 23 0,000 0,03494686 0,04943283 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03494686 0,04940245 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03494686 0,04937211 ! regulation of amine transport GO:0051952 38 23 0,000 0,03494686 0,0493418 ! liver development GO:0001889 40 23 0,000 0,03494686 0,04931153 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,0364393 0,05138589 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,0364393 0,05135441 ! initiation of viral infection GO:0019059 42 24 0,000 0,0364393 0,05132296 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,0364393 0,05129155 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,0364393 0,05126018 ! superoxide metabolic process GO:0006801 32 24 0,000 0,0364393 0,05122884 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,0364393 0,05119755 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,0364393 0,05116629 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,0364393 0,05113508 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,0364393 0,0511039 ! sperm motility GO:0030317 27 24 0,000 0,0364393 0,05107275 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,0364393 0,05104165 ! vacuole organization GO:0007033 39 24 0,000 0,0364393 0,05101058 ! receptor metabolic process GO:0043112 37 24 0,000 0,0364393 0,05097956 ! neural crest cell development GO:0014032 39 24 0,000 0,0364393 0,05094856 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,0364393 0,05091761 ! primary neural tube formation GO:0014020 35 24 0,000 0,0364393 0,0508867 ! negative regulation of cell development GO:0010721 56 24 0,000 0,0364393 0,05085582 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,0364393 0,05082498 ! base-excision repair GO:0006284 31 24 0,000 0,0364393 0,05079418 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,0364393 0,05076341 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,0364393 0,05073268 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,0364393 0,05070199 ! glutathione metabolic process GO:0006749 29 24 0,000 0,0364393 0,05067134 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,0364393 0,05064072 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,0364393 0,05061014 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,0364393 0,0505796 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03792951 0,05261633 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03792951 0,05258462 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03792951 0,05255294 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03792951 0,0525213 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03792951 0,0524897 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03792951 0,05245814 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03792951 0,05242661 ! peptide transport GO:0015833 43 25 0,000 0,03792951 0,05239512 ! male gonad development GO:0008584 33 25 0,000 0,03792951 0,05236367 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03792951 0,05233226 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03792951 0,05230089 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03792951 0,05226955 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03792951 0,05223825 ! phospholipid transport GO:0015914 35 25 0,000 0,03792951 0,05220699 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03792951 0,05217577 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03792951 0,05214458 ! detection of light stimulus GO:0009583 30 25 0,000 0,03792951 0,05211343 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03792951 0,05208232 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03792951 0,05205124 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03792951 0,0520202 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03792951 0,0519892 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03941751 0,05399658 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03941751 0,05396444 ! translational initiation GO:0006413 43 26 0,000 0,03941751 0,05393234 ! regulation of pH GO:0006885 36 26 0,000 0,03941751 0,05390028 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03941751 0,05386825 ! circadian rhythm GO:0007623 42 26 0,000 0,03941751 0,05383626 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03941751 0,05380431 ! post-embryonic development GO:0009791 42 26 0,000 0,03941751 0,0537724 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03941751 0,05374052 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03941751 0,05370869 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03941751 0,05367689 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03941751 0,05364513 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03941751 0,0536134 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03941751 0,05358172 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03941751 0,05355007 ! regulation of coagulation GO:0050818 39 26 0,000 0,03941751 0,05351846 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04090328 0,05550298 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04090328 0,05547025 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04090328 0,05543757 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04090328 0,05540492 ! membrane docking GO:0022406 39 27 0,000 0,04090328 0,05537231 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04090328 0,05533974 ! catechol metabolic process GO:0009712 43 27 0,000 0,04090328 0,0553072 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04090328 0,05527471 ! acute-phase response GO:0006953 42 27 0,000 0,04090328 0,05524225 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04090328 0,05520983 ! myofibril assembly GO:0030239 36 27 0,000 0,04090328 0,05517745 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04090328 0,05514511 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04090328 0,0551128 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04090328 0,05508053 ! natural killer cell activation GO:0030101 35 27 0,000 0,04090328 0,0550483 ! lipid oxidation GO:0034440 38 27 0,000 0,04090328 0,05501611 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04090328 0,05498396 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04090328 0,05495184 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04090328 0,05491976 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04090328 0,05488772 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04090328 0,05485572 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04090328 0,05482375 ! gene silencing GO:0016458 41 27 0,000 0,04090328 0,05479182 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04238685 0,05674607 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04238685 0,05671306 ! phenol metabolic process GO:0018958 44 28 0,000 0,04238685 0,05668009 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04238685 0,05664715 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04238685 0,05661426 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04238685 0,0565814 ! cell junction assembly GO:0034329 56 28 0,000 0,04238685 0,05654858 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04238685 0,0565158 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04238685 0,05648305 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04238685 0,05645035 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04238685 0,05641768 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04238685 0,05638505 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04238685 0,05635246 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04238685 0,0563199 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04238685 0,05628738 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04238685 0,0562549 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04238685 0,05622246 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04238685 0,05619006 ! mesoderm formation GO:0001707 46 28 0,000 0,04238685 0,05615769 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04238685 0,05612536 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04238685 0,05609307 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04238685 0,05606081 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04238685 0,05602859 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04238685 0,05599641 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04238685 0,05596426 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04238685 0,05593216 ! neural tube formation GO:0001841 41 28 0,000 0,04238685 0,05590009 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04238685 0,05586805 ! placenta development GO:0001890 37 28 0,000 0,04238685 0,05583605 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,0438682 0,05775436 ! regulation of innate immune response GO:0045088 38 29 0,000 0,0438682 0,05772132 ! ovulation cycle process GO:0022602 41 29 0,000 0,0438682 0,05768832 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,0438682 0,05765535 ! protein targeting to membrane GO:0006612 53 29 0,000 0,0438682 0,05762242 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,0438682 0,05758953 ! mismatch repair GO:0006298 34 29 0,000 0,0438682 0,05755668 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,0438682 0,05752387 ! muscle cell development GO:0055001 38 29 0,000 0,0438682 0,05749109 ! formation of primary germ layer GO:0001704 48 29 0,000 0,0438682 0,05745835 ! telencephalon development GO:0021537 52 29 0,000 0,0438682 0,05742565 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,0438682 0,05739298 ! eye morphogenesis GO:0048592 51 29 0,000 0,0438682 0,05736035 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,0438682 0,05732776 ! tissue homeostasis GO:0001894 42 29 0,000 0,0438682 0,05729521 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04534735 0,05919347 ! organic anion transport GO:0015711 51 30 0,000 0,04534735 0,0591599 ! cholesterol transport GO:0030301 46 30 0,000 0,04534735 0,05912636 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04534735 0,05909286 ! spindle organization GO:0007051 37 30 0,000 0,04534735 0,0590594 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04534735 0,05902598 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04534735 0,05899259 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04534735 0,05895924 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04534735 0,05892593 ! ovulation cycle GO:0042698 43 30 0,000 0,04534735 0,05889266 ! hindbrain development GO:0030902 45 30 0,000 0,04534735 0,05885943 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04534735 0,05882623 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04534735 0,05879307 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04534735 0,05875995 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04534735 0,05872686 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04534735 0,05869381 ! response to heat GO:0009408 41 30 0,000 0,04534735 0,0586608 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04534735 0,05862783 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04534735 0,05859489 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04682429 0,06046933 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04682429 0,06043539 ! mammary gland development GO:0030879 57 31 0,000 0,04682429 0,0604015 ! glial cell differentiation GO:0010001 55 31 0,000 0,04682429 0,06036764 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04682429 0,06033382 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04682429 0,06030004 ! odontogenesis GO:0042476 50 31 0,000 0,04682429 0,0602663 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04682429 0,06023259 ! segmentation GO:0035282 41 31 0,000 0,04682429 0,06019892 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04682429 0,06016529 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04682429 0,0601317 ! metanephros development GO:0001656 58 31 0,000 0,04682429 0,06009814 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04682429 0,06006463 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04682429 0,06003114 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04682429 0,0599977 ! cell fate specification GO:0001708 37 31 0,000 0,04682429 0,05996429 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04682429 0,05993093 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04682429 0,05989759 ! RNA modification GO:0009451 40 31 0,000 0,04682429 0,0598643 ! regulation of muscle development GO:0048634 48 32 0,000 0,04829904 0,06171543 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04829904 0,06168117 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04829904 0,06164694 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,04829904 0,06161275 ! meiosis I GO:0007127 52 32 0,000 0,04829904 0,06157859 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,04829904 0,06154448 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,04829904 0,0615104 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04829904 0,06147636 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04829904 0,06144236 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04829904 0,06140839 ! regulation of protein stability GO:0031647 48 32 0,000 0,04829904 0,06137447 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04829904 0,06134058 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04829904 0,06130672 ! cytokine production GO:0001816 44 32 0,000 0,04829904 0,06127291 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04829904 0,06123913 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04829904 0,06120539 ! vesicle localization GO:0051648 47 32 0,000 0,04829904 0,06117169 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04977158 0,063002 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,04977158 0,06296735 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04977158 0,06293273 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04977158 0,06289815 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04977158 0,06286361 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04977158 0,06282911 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04977158 0,06279465 ! ear morphogenesis GO:0042471 42 33 0,000 0,04977158 0,06276022 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04977158 0,06272583 ! cell junction organization GO:0034330 63 33 0,000 0,04977158 0,06269148 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04977158 0,06265716 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04977158 0,06262289 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04977158 0,06258865 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04977158 0,06255445 ! female gonad development GO:0008585 49 33 0,000 0,04977158 0,06252028 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04977158 0,06248616 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04977158 0,06245207 ! lipid homeostasis GO:0055088 55 33 0,000 0,04977158 0,06241801 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04977158 0,062384 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04977158 0,06235002 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04977158 0,06231608 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04977158 0,06228218 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04977158 0,06224831 ! cytokinesis GO:0000910 52 33 0,000 0,04977158 0,06221448 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04977158 0,06218068 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05124193 0,06398287 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05124193 0,06394815 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05124193 0,06391347 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05124193 0,06387883 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05124193 0,06384423 ! feeding behavior GO:0007631 45 34 0,000 0,05124193 0,06380966 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05124193 0,06377513 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05124193 0,06374064 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05124193 0,06370619 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05124193 0,06367177 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05124193 0,06363739 ! neuron migration GO:0001764 46 34 0,000 0,05124193 0,06360305 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05124193 0,06356874 ! female gamete generation GO:0007292 43 34 0,000 0,05124193 0,06353447 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05124193 0,06350024 ! polyol metabolic process GO:0019751 44 34 0,000 0,05124193 0,06346605 ! aerobic respiration GO:0009060 47 34 0,000 0,05124193 0,06343189 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05124193 0,06339777 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05124193 0,06336368 ! embryonic organ development GO:0048568 45 34 0,000 0,05124193 0,06332963 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05124193 0,06329562 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05271009 0,06507419 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05271009 0,06503928 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05271009 0,06500441 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05271009 0,06496957 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05271009 0,06493477 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,05271009 0,06490001 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05271009 0,06486528 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05271009 0,0648306 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05271009 0,06479595 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05271009 0,06476133 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05271009 0,06472676 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05271009 0,06469222 ! pigment metabolic process GO:0042440 61 35 0,000 0,05271009 0,06465772 ! protein homooligomerization GO:0051260 52 35 0,000 0,05271009 0,06462325 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05417607 0,06638516 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05417607 0,06634982 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05417607 0,0663145 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05417607 0,06627923 ! negative regulation of binding GO:0051100 58 36 0,000 0,05417607 0,06624399 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05417607 0,0662088 ! tissue remodeling GO:0048771 62 36 0,000 0,05417607 0,06617363 ! neural tube development GO:0021915 50 36 0,000 0,05417607 0,06613851 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05417607 0,06610342 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05417607 0,06606837 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05417607 0,06603336 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05417607 0,06599839 ! glucan metabolic process GO:0044042 49 36 0,000 0,05417607 0,06596345 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05563986 0,06770988 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05563986 0,06767407 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05563986 0,0676383 ! learning GO:0007612 67 37 0,000 0,05563986 0,06760257 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05563986 0,06756688 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05563986 0,06753122 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05563986 0,0674956 ! amino acid activation GO:0043038 52 37 0,000 0,05563986 0,06746002 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05563986 0,06742448 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05710146 0,06915922 ! gliogenesis GO:0042063 71 38 0,000 0,05710146 0,06912282 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,05710146 0,06908646 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05710146 0,06905014 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05710146 0,06901385 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05710146 0,06897761 ! phagocytosis GO:0006909 60 38 0,000 0,05710146 0,0689414 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05710146 0,06890523 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05710146 0,06886909 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05710146 0,068833 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,05856089 0,07055529 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05856089 0,07051835 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05856089 0,07048145 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,05856089 0,07044458 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05856089 0,07040776 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,05856089 0,07037097 ! male sex differentiation GO:0046661 53 39 0,000 0,05856089 0,07033423 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05856089 0,07029752 ! chromatin remodeling GO:0006338 68 39 0,000 0,05856089 0,07026085 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05856089 0,07022422 ! JNK cascade GO:0007254 54 39 0,000 0,05856089 0,07018762 ! developmental growth GO:0048589 62 39 0,000 0,05856089 0,07015107 ! cell growth GO:0016049 61 39 0,000 0,05856089 0,07011455 ! synapse organization GO:0050808 55 39 0,000 0,05856089 0,07007807 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06001814 0,07178457 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06001814 0,07174726 ! regulation of tube size GO:0035150 60 40 0,000 0,06001814 0,07170999 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06001814 0,07167276 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06001814 0,07163556 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06001814 0,07159841 ! peptide metabolic process GO:0006518 56 40 0,000 0,06001814 0,07156129 ! inner ear development GO:0048839 57 40 0,000 0,06001814 0,07152421 ! T cell differentiation GO:0030217 65 40 0,000 0,06001814 0,07148717 ! double-strand break repair GO:0006302 67 40 0,000 0,06001814 0,07145017 ! B cell differentiation GO:0030183 62 40 0,000 0,06001814 0,07141321 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,06001814 0,07137628 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06001814 0,07133939 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06001814 0,07130254 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06001814 0,07126573 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06147322 0,07295584 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06147322 0,07291821 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06147322 0,07288062 ! glucose transport GO:0015758 52 41 0,000 0,06147322 0,07284308 ! endosome transport GO:0016197 71 41 0,000 0,06147322 0,07280557 ! striated muscle contraction GO:0006941 62 41 0,000 0,06147322 0,0727681 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06147322 0,07273066 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06147322 0,07269327 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06147322 0,07265592 ! biopolymer methylation GO:0043414 62 41 0,000 0,06147322 0,0726186 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06147322 0,07258132 ! mitochondrial transport GO:0006839 60 42 0,000 0,06292613 0,07425865 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06292613 0,07422057 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06292613 0,07418253 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06292613 0,07414452 ! cellular component disassembly GO:0022411 64 42 0,000 0,06292613 0,07410656 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06292613 0,07406863 ! hexose transport GO:0008645 54 42 0,000 0,06292613 0,07403075 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06292613 0,0739929 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06292613 0,07395509 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06292613 0,07391732 ! excretion GO:0007588 63 42 0,000 0,06292613 0,07387958 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06292613 0,07384189 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06292613 0,07380424 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06292613 0,07376662 ! regulation of cell shape GO:0008360 78 42 0,000 0,06292613 0,07372904 ! positive regulation of binding GO:0051099 59 43 0,000 0,06437688 0,07539044 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06437688 0,07535207 ! leukocyte migration GO:0050900 60 43 0,000 0,06437688 0,07531374 ! neuromuscular process GO:0050905 79 43 0,000 0,06437688 0,07527546 ! activation of caspase activity GO:0006919 65 43 0,000 0,06437688 0,07523721 ! tRNA processing GO:0008033 49 43 0,000 0,06437688 0,07519899 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06437688 0,07516082 ! vesicle organization GO:0016050 79 43 0,000 0,06437688 0,07512269 ! response to insulin stimulus GO:0032868 63 43 0,000 0,06437688 0,07508459 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06437688 0,07504654 ! methylation GO:0032259 64 43 0,000 0,06437688 0,07500852 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,06582546 0,0766575 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,06582546 0,0766187 ! glycolysis GO:0006096 53 44 0,000 0,06582546 0,07657995 ! regulation of action potential GO:0001508 71 44 0,000 0,06582546 0,07654123 ! regulation of ion transport GO:0043269 57 44 0,000 0,06582546 0,07650256 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,06582546 0,07646392 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,06582546 0,07642532 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,06582546 0,07638676 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,06582546 0,07634824 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,06582546 0,07630976 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,06582546 0,07627131 ! RNA catabolic process GO:0006401 64 45 0,000 0,06727188 0,07790802 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06727188 0,07786881 ! regulation of translational initiation GO:0006446 64 45 0,000 0,06727188 0,07782964 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06727188 0,07779051 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06727188 0,07775142 ! cell recognition GO:0008037 58 45 0,000 0,06727188 0,07771237 ! cell maturation GO:0048469 60 45 0,000 0,06727188 0,07767336 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06727188 0,07763439 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,06871615 0,07926135 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,06871615 0,07922162 ! cell redox homeostasis GO:0045454 63 46 0,000 0,06871615 0,07918193 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,06871615 0,07914228 ! regulation of ossification GO:0030278 71 46 0,000 0,06871615 0,07910267 ! histone modification GO:0016570 68 46 0,000 0,06871615 0,0790631 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,06871615 0,07902357 ! viral infectious cycle GO:0019058 71 47 0,000 0,07015826 0,08064168 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07015826 0,0806014 ! endocrine system development GO:0035270 83 47 0,000 0,07015826 0,08056116 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07015826 0,08052096 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07015826 0,0804808 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07015826 0,08044068 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07015826 0,0804006 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07015826 0,08036056 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07015826 0,08032056 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07015826 0,0802806 ! chloride transport GO:0006821 67 48 0,000 0,07159822 0,08188757 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07159822 0,08184687 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07159822 0,08180621 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07159822 0,0817656 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07159822 0,08172502 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07159822 0,08168448 ! gastrulation GO:0007369 73 48 0,000 0,07159822 0,08164398 ! heart morphogenesis GO:0003007 65 48 0,000 0,07159822 0,08160352 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07159822 0,08156311 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07159822 0,08152273 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07159822 0,08148239 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07159822 0,08144209 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07159822 0,08140183 ! nuclear export GO:0051168 69 48 0,000 0,07159822 0,08136162 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07159822 0,08132144 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07159822 0,0812813 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07303604 0,08287266 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07303604 0,0828318 ! sensory perception of smell GO:0007608 61 49 0,000 0,07303604 0,08279097 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07303604 0,08275019 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07303604 0,08270944 ! RNA elongation GO:0006354 62 49 0,000 0,07303604 0,08266874 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07303604 0,08262808 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07303604 0,08258745 ! germ cell development GO:0007281 68 49 0,000 0,07303604 0,08254687 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07303604 0,08250633 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07303604 0,08246582 ! cartilage development GO:0051216 70 49 0,000 0,07303604 0,08242536 ! maintenance of location GO:0051235 84 49 0,000 0,07303604 0,08238493 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07447171 0,0839632 ! ear development GO:0043583 72 50 0,000 0,07447171 0,08392206 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,07447171 0,08388096 ! membrane fusion GO:0006944 80 50 0,000 0,07447171 0,0838399 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07447171 0,08379889 ! lipid modification GO:0030258 73 50 0,000 0,07447171 0,08375791 ! positive regulation of growth GO:0045927 67 50 0,000 0,07447171 0,08371697 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07447171 0,08367607 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07447171 0,08363522 ! positive regulation of secretion GO:0051047 71 51 0,000 0,07590523 0,08520353 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,07590523 0,08516197 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,07590523 0,08512045 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,07590523 0,08507897 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,07590523 0,08503752 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,07590523 0,08499612 ! adult behavior GO:0030534 80 51 0,000 0,07590523 0,08495476 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,07590523 0,08491344 ! transition metal ion transport GO:0000041 74 52 0,000 0,07733662 0,08647265 ! regulation of cellular component size GO:0032535 74 52 0,000 0,07733662 0,08643063 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,07733662 0,08638865 ! aging GO:0007568 79 52 0,000 0,07733662 0,08634672 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,07733662 0,08630482 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,07733662 0,08626297 ! establishment of organelle localization GO:0051656 85 52 0,000 0,07733662 0,08622115 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,07876588 0,08777205 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,07876588 0,08772955 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,07876588 0,08768709 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,07876588 0,08764466 ! kidney development GO:0001822 90 53 0,000 0,07876588 0,08760228 ! single fertilization GO:0007338 59 53 0,000 0,07876588 0,08755994 ! cell projection assembly GO:0030031 76 53 0,000 0,07876588 0,08751764 ! amino acid transport GO:0006865 84 54 0,000 0,080193 0,08906031 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,080193 0,08901733 ! regulation of mitosis GO:0007088 84 54 0,000 0,080193 0,08897439 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,080193 0,08893149 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,080193 0,08888863 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,080193 0,08884581 ! DNA catabolic process GO:0006308 67 54 0,000 0,080193 0,08880303 ! detection of external stimulus GO:0009581 66 54 0,000 0,080193 0,0887603 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,080193 0,08871761 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,080193 0,08867495 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,080193 0,08863234 ! exocytosis GO:0006887 74 55 0,000 0,08161799 0,09016397 ! mesoderm development GO:0007498 76 55 0,000 0,08161799 0,09012069 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08161799 0,09007744 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08161799 0,09003424 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,08304086 0,09155992 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,08304086 0,09151604 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,08304086 0,09147221 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,08304086 0,09142843 ! carbohydrate transport GO:0008643 74 57 0,000 0,08446161 0,09294818 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,08446161 0,09290373 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,08446161 0,09285932 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,08446161 0,09281495 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,08446161 0,09277063 ! camera-type eye development GO:0043010 88 57 0,000 0,08446161 0,09272635 ! secondary metabolic process GO:0019748 84 57 0,000 0,08446161 0,09268211 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,08446161 0,09263791 ! developmental maturation GO:0021700 75 57 0,000 0,08446161 0,09259375 ! gonad development GO:0008406 79 57 0,000 0,08446161 0,09254964 ! viral reproductive process GO:0022415 87 58 0,000 0,08588023 0,0940593 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,08588023 0,09401453 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,08588023 0,09396981 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,08588023 0,09392512 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,08729674 0,09542895 ! activation of MAPK activity GO:0000187 84 59 0,000 0,08729674 0,09538361 ! lung development GO:0030324 94 59 0,000 0,08729674 0,09533832 ! actin filament organization GO:0007015 95 59 0,000 0,08729674 0,09529307 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,08729674 0,09524787 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,08729674 0,0952027 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,08871113 0,09669934 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,08871113 0,09665353 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,08871113 0,09660777 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,08871113 0,09656205 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,08871113 0,09651637 ! regulation of heart contraction GO:0008016 91 60 0,000 0,08871113 0,09647074 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,08871113 0,09642515 ! fertilization GO:0009566 68 60 0,000 0,08871113 0,0963796 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,08871113 0,09633409 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09012342 0,09782155 ! meiosis GO:0007126 96 61 0,000 0,09012342 0,09777541 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09012342 0,09772931 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09012342 0,09768325 ! urogenital system development GO:0001655 101 61 0,000 0,09012342 0,09763724 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09012342 0,09759127 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09012342 0,09754535 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09012342 0,09749946 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,09153359 0,0989785 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09153359 0,09893198 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09153359 0,09888552 ! respiratory tube development GO:0030323 99 62 0,000 0,09153359 0,09883909 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09153359 0,09879271 ! meiotic cell cycle GO:0051321 97 62 0,000 0,09153359 0,09874637 ! organelle localization GO:0051640 96 62 0,000 0,09153359 0,09870008 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09294166 0,10017143 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09294166 0,10012451 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09294166 0,10007763 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09294166 0,1000308 ! viral reproduction GO:0016032 92 63 0,000 0,09294166 0,09998402 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09294166 0,09993727 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,09434763 0,10140166 ! appendage morphogenesis GO:0035107 93 64 0,000 0,09434763 0,1013543 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,09434763 0,10130698 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,09434763 0,10125971 ! hexose catabolic process GO:0019320 82 64 0,000 0,09434763 0,10121248 ! respiratory system development GO:0060541 100 64 0,000 0,09434763 0,10116529 ! adaptive immune response GO:0002250 94 64 0,000 0,09434763 0,10111815 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,0957515 0,10257497 ! regulation of caspase activity GO:0043281 97 65 0,000 0,0957515 0,10252721 ! appendage development GO:0048736 94 65 0,000 0,0957515 0,10247951 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,0957515 0,10243184 ! defense response to bacterium GO:0042742 73 65 0,000 0,0957515 0,10238422 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,0957515 0,10233664 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,0957515 0,10228911 ! activation of immune response GO:0002253 83 65 0,000 0,0957515 0,10224162 ! protein oligomerization GO:0051259 100 65 0,000 0,0957515 0,10219418 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,09715328 0,10364218 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,09715328 0,10359413 ! antigen processing and presentation GO:0019882 96 66 0,000 0,09715328 0,10354613 ! axon guidance GO:0007411 99 66 0,000 0,09715328 0,10349816 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,09715328 0,10345025 ! regulation of immune effector process GO:0002697 101 66 0,000 0,09715328 0,10340238 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,09855296 0,10484357 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,09855296 0,1047951 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,09855296 0,10474668 ! acute inflammatory response GO:0002526 92 68 0,000 0,09995055 0,10618303 ! learning or memory GO:0007611 123 68 0,000 0,09995055 0,10613401 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,09995055 0,10608503 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,09995055 0,1060361 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,09995055 0,10598721 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,09995055 0,10593837 ! rhythmic process GO:0048511 105 68 0,000 0,09995055 0,10588958 ! inorganic anion transport GO:0015698 93 68 0,000 0,09995055 0,10584082 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10134606 0,10726918 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10134606 0,10721984 ! response to drug GO:0042493 108 69 0,000 0,10134606 0,10717054 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10273948 0,10859412 ! humoral immune response GO:0006959 86 70 0,000 0,10273948 0,10854424 ! eye development GO:0001654 111 70 0,000 0,10273948 0,1084944 ! amine transport GO:0015837 101 70 0,000 0,10273948 0,10844461 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10273948 0,10839486 ! regulation of catabolic process GO:0009894 106 70 0,000 0,10273948 0,10834516 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,10413082 0,10976209 ! muscle cell differentiation GO:0042692 104 71 0,000 0,10413082 0,10971181 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,10413082 0,10966158 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,10413082 0,10961139 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,10413082 0,10956125 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,10413082 0,10951115 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,10552008 0,11092148 ! response to hypoxia GO:0001666 132 72 0,000 0,10552008 0,11087081 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,10552008 0,11082018 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,10552008 0,1107696 ! negative regulation of transport GO:0051051 116 73 0,000 0,10690727 0,1121746 ! regulation of blood pressure GO:0008217 107 73 0,000 0,10690727 0,11212345 ! tube morphogenesis GO:0035239 118 73 0,000 0,10690727 0,11207235 ! mitochondrion organization GO:0007005 104 73 0,000 0,10690727 0,11202129 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,10690727 0,11197028 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,10690727 0,11191931 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,10829239 0,11331779 ! response to oxygen levels GO:0070482 137 74 0,000 0,10829239 0,11326626 ! digestion GO:0007586 97 74 0,000 0,10829239 0,11321477 ! protein import into nucleus GO:0006606 118 74 0,000 0,10829239 0,11316333 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,10829239 0,11311194 ! blood coagulation GO:0007596 116 75 0,000 0,10967544 0,11450454 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,10967544 0,11445259 ! nuclear import GO:0051170 121 75 0,000 0,10967544 0,11440068 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,10967544 0,11434883 ! amine biosynthetic process GO:0009309 97 76 0,000 0,11105642 0,11573619 ! tRNA metabolic process GO:0006399 95 76 0,000 0,11105642 0,11568377 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,11105642 0,1156314 ! regulation of protein transport GO:0051223 114 76 0,000 0,11105642 0,11557908 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,11243534 0,11696123 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,11243534 0,11690836 ! regulation of DNA binding GO:0051101 119 77 0,000 0,11243534 0,11685553 ! gland development GO:0048732 148 77 0,000 0,11243534 0,11680275 ! sex differentiation GO:0007548 105 77 0,000 0,11243534 0,11675002 ! protein ubiquitination GO:0016567 125 77 0,000 0,11243534 0,11669733 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,11243534 0,11664469 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,11243534 0,1165921 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,11243534 0,11653956 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,1138122 0,11791354 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,1138122 0,11786045 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,115187 0,11923047 ! T cell activation GO:0042110 134 79 0,000 0,115187 0,11917684 ! regulation of lyase activity GO:0051339 133 79 0,000 0,115187 0,11912325 ! alcohol catabolic process GO:0046164 104 80 0,000 0,11655975 0,12048873 ! protein localization in nucleus GO:0034504 133 80 0,000 0,11655975 0,1204346 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,11655975 0,12038053 ! forebrain development GO:0030900 131 80 0,000 0,11655975 0,12032649 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,11793045 0,12168687 ! hemostasis GO:0007599 125 81 0,000 0,11793045 0,1216323 ! mRNA transport GO:0051028 121 81 0,000 0,11793045 0,12157778 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,11793045 0,12152331 ! regulation of neurological system process GO:0031644 122 81 0,000 0,11793045 0,12146889 ! vitamin metabolic process GO:0006766 103 81 0,000 0,11793045 0,12141452 ! ossification GO:0001503 134 82 0,000 0,1192991 0,12276865 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1192991 0,12271374 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12066571 0,12406398 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12066571 0,12400854 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,12066571 0,12395316 ! regulation of defense response GO:0031347 117 84 0,000 0,12203027 0,12529894 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,12203027 0,12524302 ! sterol metabolic process GO:0016125 120 84 0,000 0,12203027 0,12518716 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,12339279 0,1265285 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,12339279 0,12647211 ! rRNA metabolic process GO:0016072 107 85 0,000 0,12339279 0,12641578 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,12339279 0,12635949 ! transcription initiation GO:0006352 118 85 0,000 0,12339279 0,12630326 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,12339279 0,12624707 ! regulation of protein localization GO:0032880 132 85 0,000 0,12339279 0,12619094 ! regulation of membrane potential GO:0042391 128 85 0,000 0,12339279 0,12613485 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,12339279 0,12607882 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,12475328 0,12741232 ! cellular defense response GO:0006968 102 87 0,000 0,12611173 0,12874256 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,12611173 0,12868544 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,12611173 0,12862837 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,12611173 0,12857136 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,12746816 0,12989666 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,12746816 0,12983913 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,12746816 0,12978165 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,12746816 0,12972423 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,12882255 0,13104461 ! reproductive developmental process GO:0003006 127 89 0,000 0,12882255 0,13098668 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,12882255 0,1309288 ! regulation of T cell activation GO:0050863 128 89 0,000 0,12882255 0,13087097 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13017492 0,13218646 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13017492 0,13212812 ! hormone metabolic process GO:0042445 121 90 0,000 0,13017492 0,13206984 ! RNA localization GO:0006403 135 91 0,000 0,13152527 0,13338101 ! response to virus GO:0009615 122 91 0,000 0,13152527 0,13332222 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,1328736 0,13462964 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,1328736 0,13457036 ! cell fate commitment GO:0045165 141 92 0,000 0,1328736 0,13451113 ! positive regulation of immune response GO:0050778 121 92 0,000 0,1328736 0,13445195 ! DNA recombination GO:0006310 146 92 0,000 0,1328736 0,13439283 ! sulfur metabolic process GO:0006790 118 92 0,000 0,1328736 0,13433375 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,13421992 0,13563524 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,13421992 0,13557567 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,13421992 0,13551616 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,13421992 0,1354567 ! regulation of binding GO:0051098 151 95 0,000 0,13690651 0,13810744 ! angiogenesis GO:0001525 149 95 0,000 0,13690651 0,1380469 ! carboxylic acid transport GO:0046942 147 95 0,000 0,13690651 0,1379864 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,13824679 0,13927623 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,13824679 0,13921525 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,13824679 0,13915432 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,13824679 0,13909345 ! protein maturation GO:0051604 129 96 0,000 0,13824679 0,13903263 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,13958507 0,14031716 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,13958507 0,14025586 ! calcium ion transport GO:0006816 167 99 0,000 0,14225563 0,14287684 ! extracellular structure organization GO:0043062 156 99 0,000 0,14225563 0,14281447 ! protein import GO:0017038 156 99 0,000 0,14225563 0,14275216 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,14225563 0,14268991 ! regulation of translation GO:0006417 151 100 0,000 0,14358792 0,14396347 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,14358792 0,14390075 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,14358792 0,14383807 ! divalent metal ion transport GO:0070838 171 100 0,000 0,14358792 0,14377545 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,14358792 0,14371289 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,14358792 0,14365037 ! protein localization in organelle GO:0033365 161 100 0,000 0,14358792 0,14358792