pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/9551-11-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mRNA cleavage GO:0006379 17 10 2,000 1,716E-07 4,128E-04 ! mRNA polyadenylation GO:0006378 23 12 2,000 3,14E-07 3,778E-04 ! mRNA 3'-end processing GO:0031124 24 13 2,000 4,079E-07 3,272E-04 ! RNA polyadenylation GO:0043631 30 14 2,000 5,188E-07 3,12E-04 ! RNA 3'-end processing GO:0031123 34 17 2,000 9,668E-07 4,652E-04 ! collagen catabolic process GO:0030574 28 21 2,000 1,885E-06 7,558E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,249E-06 1,117E-03 ! multicellular organismal catabolic process GO:0044243 36 27 2,000 4,126E-06 1,241E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 4,512E-06 1,206E-03 ! interphase GO:0051325 213 98 3,000 5,107E-06 1,229E-03 ! collagen metabolic process GO:0032963 45 31 2,000 6,32E-06 1,382E-03 ! spliceosome assembly GO:0000245 67 32 2,000 6,968E-06 1,397E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 8,393E-06 1,553E-03 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 1,309E-05 2,25E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,379E-05 2,212E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,109E-05 3,171E-03 ! ribonucleoprotein complex assembly GO:0022618 95 49 2,000 2,553E-05 3,614E-03 ! response to UV GO:0009411 104 53 2,000 3,236E-05 4,326E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,658E-05 4,632E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 4,03E-05 4,848E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 5,87E-05 6,725E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 5,87E-05 6,419E-03 ! thymus development GO:0048538 27 11 1,000 7,169E-05 7,499E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 8,596E-05 8,618E-03 ! T cell homeostasis GO:0043029 25 12 1,000 8,596E-05 8,273E-03 ! mRNA splice site selection GO:0006376 38 15 1,000 1,365E-04 0,01262773 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,365E-04 0,01216003 ! DNA replication initiation GO:0006270 27 16 1,000 1,558E-04 0,01339107 ! DNA unwinding during replication GO:0006268 27 17 1,000 1,765E-04 0,01464253 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,216E-04 0,01777116 GO:0030968|endoplasmic reticulum unfolded protein response, ! DNA duplex unwinding GO:0032508 31 20 1,000 2,46E-04 0,01909483 GO:0032392|DNA geometric change, ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,987E-04 0,02245701 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,563E-04 0,02598072 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,563E-04 0,02521658 ! leukocyte homeostasis GO:0001776 44 24 1,000 3,563E-04 0,02449611 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,87E-04 0,02586771 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,19E-04 0,02724607 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,522E-04 0,0286305 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 4,522E-04 0,02789638 ! fat cell differentiation GO:0045444 50 27 1,000 4,522E-04 0,02719897 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,866E-04 0,02855594 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,223E-04 0,02991909 ! regulation of B cell activation GO:0050864 50 30 1,000 5,592E-04 0,03128785 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 8,063E-04 0,04409023 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 8,984E-04 0,04803568 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,259E-03 0,06583891 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 1,259E-03 0,06443809 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! response to calcium ion GO:0051592 81 47 1,000 1,372E-03 0,06879499 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,431E-03 0,07026984 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,431E-03 0,06886445 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 1,491E-03 0,07033584 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,614E-03 0,07468161 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! respiratory electron transport chain GO:0022904 76 53 1,000 1,742E-03 0,07907651 ! proton transport GO:0015992 94 56 1,000 1,942E-03 0,08654705 ! hydrogen transport GO:0006818 97 58 1,000 2,082E-03 0,09107581 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 2,767E-03 0,11886354 ! negative regulation of cell growth GO:0030308 132 67 1,000 2,767E-03 0,11677822 ! homeostasis of number of cells GO:0048872 114 67 1,000 2,767E-03 0,1147648 ! negative regulation of kinase activity GO:0033673 131 68 1,000 2,848E-03 0,11615387 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 2,848E-03 0,11421797 ! negative regulation of cell size GO:0045792 134 69 1,000 2,931E-03 0,11561499 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 2,931E-03 0,11375024 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 3,187E-03 0,12169942 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 3,187E-03 0,11979786 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 3,187E-03 0,11795482 ! negative regulation of transferase activity GO:0051348 140 72 1,000 3,187E-03 0,11616763 ! positive regulation of ligase activity GO:0051351 124 77 1,000 3,635E-03 0,13052344 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 3,635E-03 0,12860397 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 3,822E-03 0,13326007 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 3,822E-03 0,13135636 ! response to metal ion GO:0010038 140 80 1,000 3,917E-03 0,13273041 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 4,013E-03 0,134103 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 4,308E-03 0,14199842 ! regulation of ligase activity GO:0051340 142 84 1,000 4,308E-03 0,14007952 ! response to unfolded protein GO:0006986 131 85 1,000 4,409E-03 0,14143937 ! nucleosome assembly GO:0006334 122 85 1,000 4,409E-03 0,13957832 ! positive regulation of cell activation GO:0050867 145 85 1,000 4,409E-03 0,13776562 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 4,511E-03 0,13913632 ! oxidative phosphorylation GO:0006119 133 86 1,000 4,511E-03 0,13737511 ! chromatin assembly GO:0031497 124 86 1,000 4,511E-03 0,13565792 ! cellular respiration GO:0045333 135 88 1,000 4,717E-03 0,14012109 ! positive regulation of protein modification process GO:0031401 136 88 1,000 4,717E-03 0,1384123 ! ATP biosynthetic process GO:0006754 159 88 1,000 4,717E-03 0,13674468 ! protein-DNA complex assembly GO:0065004 130 90 1,000 4,928E-03 0,14115907 ! response to protein stimulus GO:0051789 149 91 1,000 5,035E-03 0,14252959 ! nucleosome organization GO:0034728 138 92 1,000 5,143E-03 0,14389819 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 5,253E-03 0,14526489 GO:0010498|proteasomal protein catabolic process, ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 5,587E-03 0,15274783 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 5,7E-03 0,15409924 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 5,798E-03 0,15498826 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,798E-03 0,1532851 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,798E-03 0,15161895 ! positive regulation of helicase activity GO:0051096 11 5 0,000 5,798E-03 0,14998864 ! neuron fate determination GO:0048664 7 5 0,000 5,798E-03 0,14839302 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,798E-03 0,14683099 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 5,798E-03 0,1453015 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,798E-03 0,14380354 ! polyol transport GO:0015791 12 5 0,000 5,798E-03 0,14233616 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 5,798E-03 0,14089842 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,798E-03 0,13948944 ! response to superoxide GO:0000303 10 5 0,000 5,798E-03 0,13810835 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,798E-03 0,13675435 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 5,798E-03 0,13542664 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 5,798E-03 0,13412446 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,798E-03 0,13284708 ! female meiosis GO:0007143 7 5 0,000 5,798E-03 0,13159381 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,798E-03 0,13036396 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,798E-03 0,12915689 ! cobalt ion transport GO:0006824 11 5 0,000 5,798E-03 0,12797196 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 5,798E-03 0,12680858 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 5,798E-03 0,12566616 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 5,798E-03 0,12454414 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,798E-03 0,12344198 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 5,798E-03 0,12235916 ! embryonic camera-type eye development GO:0031076 10 5 0,000 5,798E-03 0,12129516 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,798E-03 0,12024951 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 5,798E-03 0,11922174 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 5,798E-03 0,11821139 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,798E-03 0,11721801 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,798E-03 0,1162412 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,798E-03 0,11528053 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 5,798E-03 0,1143356 ! negative chemotaxis GO:0050919 14 5 0,000 5,798E-03 0,11340605 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,798E-03 0,11249148 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,798E-03 0,11159155 ! sensory perception of bitter taste GO:0050913 7 5 0,000 5,798E-03 0,1107059 ! behavioral response to pain GO:0048266 9 5 0,000 5,798E-03 0,1098342 ! clathrin coat assembly GO:0048268 14 5 0,000 5,798E-03 0,10897612 ! Notch receptor processing GO:0007220 8 5 0,000 5,798E-03 0,10813135 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,798E-03 0,10729957 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,798E-03 0,10648049 ! micturition GO:0060073 9 5 0,000 5,798E-03 0,10567382 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,798E-03 0,10487928 ! copulation GO:0007620 9 5 0,000 5,798E-03 0,10409659 ! glial cell fate commitment GO:0021781 13 5 0,000 5,798E-03 0,10332551 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,798E-03 0,10256576 ! spermidine metabolic process GO:0008216 7 5 0,000 5,798E-03 0,10181711 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,798E-03 0,1010793 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,798E-03 0,10035211 ! apoptotic cell clearance GO:0043277 20 5 0,000 5,798E-03 0,09963531 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,798E-03 0,09892868 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,798E-03 0,098232 ! grooming behavior GO:0007625 6 5 0,000 5,798E-03 0,09754506 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,798E-03 0,09686766 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 5,798E-03 0,09619961 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,798E-03 0,09554071 ! response to protozoan GO:0001562 10 5 0,000 5,798E-03 0,09489077 ! positive regulation of glycolysis GO:0045821 14 5 0,000 5,798E-03 0,09424962 ! lymph vessel development GO:0001945 10 5 0,000 5,798E-03 0,09361707 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 5,798E-03 0,09299296 ! endochondral ossification GO:0001958 16 5 0,000 5,798E-03 0,09237711 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,798E-03 0,09176937 ! parathyroid gland development GO:0060017 13 5 0,000 5,798E-03 0,09116957 ! anagen GO:0042640 6 5 0,000 5,798E-03 0,09057756 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,798E-03 0,08999319 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,798E-03 0,08941631 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 5,798E-03 0,08884678 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 5,798E-03 0,08828445 ! dorsal spinal cord development GO:0021516 7 5 0,000 5,798E-03 0,08772921 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 5,798E-03 0,0871809 ! sphingoid catabolic process GO:0046521 6 5 0,000 5,798E-03 0,0866394 ! skeletal myofibril assembly GO:0014866 10 5 0,000 5,798E-03 0,08610459 ! smooth muscle tissue development GO:0048745 28 5 0,000 5,798E-03 0,08557634 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,798E-03 0,08505453 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,798E-03 0,08453905 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,798E-03 0,08402978 ! cardiac muscle fiber development GO:0048739 10 5 0,000 5,798E-03 0,08352661 ! transepithelial chloride transport GO:0030321 9 5 0,000 5,798E-03 0,08302943 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,798E-03 0,08253813 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 5,798E-03 0,08205261 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 5,798E-03 0,08157277 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,798E-03 0,08109851 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,798E-03 0,08062973 ! histidine catabolic process GO:0006548 6 5 0,000 5,798E-03 0,08016634 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 5,798E-03 0,07970825 ! microvillus organization GO:0032528 7 5 0,000 5,798E-03 0,07925536 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 5,798E-03 0,07880759 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,798E-03 0,07836485 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,798E-03 0,07792706 ! tryptophan metabolic process GO:0006568 9 5 0,000 5,798E-03 0,07749413 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 5,798E-03 0,07706599 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,798E-03 0,07664255 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 5,798E-03 0,07622374 ! polyol catabolic process GO:0046174 7 5 0,000 5,798E-03 0,07580948 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,798E-03 0,0753997 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,798E-03 0,07499432 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,798E-03 0,07459328 ! muscle cell migration GO:0014812 8 5 0,000 5,798E-03 0,07419651 ! mitochondrial fission GO:0000266 8 5 0,000 5,798E-03 0,07380393 ! sister chromatid cohesion GO:0007062 12 5 0,000 5,798E-03 0,07341549 ! mRNA transcription GO:0009299 9 5 0,000 5,798E-03 0,07303112 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 5,798E-03 0,07265075 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 5,798E-03 0,07227432 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 5,798E-03 0,07190177 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,798E-03 0,07153304 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,798E-03 0,07116808 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,798E-03 0,07080682 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,798E-03 0,07044921 ! response to food GO:0032094 6 5 0,000 5,798E-03 0,07009519 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,798E-03 0,06974472 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,798E-03 0,06939773 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 5,798E-03 0,06905418 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,798E-03 0,06871401 ! paraxial mesoderm development GO:0048339 14 5 0,000 5,798E-03 0,06837717 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 5,798E-03 0,06804363 ! forebrain neuron development GO:0021884 13 5 0,000 5,798E-03 0,06771332 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,798E-03 0,0673862 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 5,798E-03 0,06706223 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,798E-03 0,06674136 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,798E-03 0,06642354 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,798E-03 0,06610874 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 5,798E-03 0,0657969 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,798E-03 0,065488 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 5,798E-03 0,06518198 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 5,798E-03 0,06487881 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,798E-03 0,06457844 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 5,798E-03 0,06428085 ! basic amino acid transport GO:0015802 11 5 0,000 5,798E-03 0,06398598 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,798E-03 0,06369381 ! early endosome to late endosome transport GO:0045022 12 5 0,000 5,798E-03 0,06340429 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,798E-03 0,06311739 ! depyrimidination GO:0045008 10 5 0,000 5,798E-03 0,06283308 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,798E-03 0,06255132 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,798E-03 0,06227207 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,798E-03 0,06199531 ! zinc ion homeostasis GO:0055069 8 5 0,000 5,798E-03 0,06172099 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 5,798E-03 0,06144909 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 5,798E-03 0,06117958 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,798E-03 0,06091242 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,798E-03 0,06064758 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,798E-03 0,06038504 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 5,798E-03 0,06012476 ! peptidyl-arginine modification GO:0018195 9 5 0,000 5,798E-03 0,05986671 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,798E-03 0,05961087 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,798E-03 0,05935721 ! response to arsenic GO:0046685 10 5 0,000 5,798E-03 0,05910569 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,798E-03 0,0588563 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,798E-03 0,05860901 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 5,798E-03 0,05836378 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 5,798E-03 0,0581206 ! response to cadmium ion GO:0046686 7 5 0,000 5,798E-03 0,05787943 ! bile acid biosynthetic process GO:0006699 6 5 0,000 5,798E-03 0,05764026 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 5,798E-03 0,05740306 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,798E-03 0,0571678 ! decidualization GO:0046697 11 5 0,000 5,798E-03 0,05693446 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 5,798E-03 0,05670302 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 5,798E-03 0,05647346 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,798E-03 0,05624574 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,798E-03 0,05601985 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 5,798E-03 0,05579577 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,798E-03 0,05557348 ! neural tube patterning GO:0021532 7 5 0,000 5,798E-03 0,05535295 ! embryonic cleavage GO:0040016 6 5 0,000 5,798E-03 0,05513416 ! peroxisome fission GO:0016559 5 5 0,000 5,798E-03 0,0549171 ! histone demethylation GO:0016577 10 5 0,000 5,798E-03 0,05470174 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 5,798E-03 0,05448806 ! mitotic recombination GO:0006312 9 5 0,000 5,798E-03 0,05427605 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,798E-03 0,05406567 ! metaphase plate congression GO:0051310 7 5 0,000 5,798E-03 0,05385693 ! regulation of sterol transport GO:0032371 7 5 0,000 5,798E-03 0,05364978 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,798E-03 0,05344423 ! enteric nervous system development GO:0048484 8 5 0,000 5,798E-03 0,05324024 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 5,798E-03 0,05303781 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 5,798E-03 0,05283691 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 5,798E-03 0,05263752 ! muscle cell proliferation GO:0033002 11 5 0,000 5,798E-03 0,05243964 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,798E-03 0,05224323 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 5,798E-03 0,0520483 ! plasminogen activation GO:0031639 5 5 0,000 5,798E-03 0,05185481 ! B cell homeostasis GO:0001782 13 5 0,000 5,798E-03 0,05166275 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,798E-03 0,05147212 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,798E-03 0,05128288 ! metaphase GO:0051323 8 5 0,000 5,798E-03 0,05109503 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 5,798E-03 0,05090855 ! cellular response to nutrient GO:0031670 8 5 0,000 5,798E-03 0,05072343 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,798E-03 0,05053965 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,798E-03 0,0503572 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,798E-03 0,05017606 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 5,798E-03 0,04999621 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 5,798E-03 0,04981766 ! response to redox state GO:0051775 5 5 0,000 5,798E-03 0,04964037 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 5,798E-03 0,04946434 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 5,798E-03 0,04928955 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,798E-03 0,049116 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,798E-03 0,04894366 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,798E-03 0,04877253 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 5,798E-03 0,04860259 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,798E-03 0,04843383 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 5,798E-03 0,04826624 ! striatum development GO:0021756 9 5 0,000 5,798E-03 0,04809981 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 5,798E-03 0,04793451 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 5,798E-03 0,04777036 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,798E-03 0,04760732 ! glial cell migration GO:0008347 11 5 0,000 5,798E-03 0,04744539 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,798E-03 0,04728455 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 5,798E-03 0,04712481 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,798E-03 0,04696614 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,798E-03 0,04680854 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,798E-03 0,04665199 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,798E-03 0,04649648 ! neuroprotection GO:0043526 6 5 0,000 5,798E-03 0,04634201 ! neural plate development GO:0001840 8 5 0,000 5,798E-03 0,04618856 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,798E-03 0,04603612 ! regulation of sensory perception GO:0051931 7 5 0,000 5,798E-03 0,04588468 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,798E-03 0,04573424 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,798E-03 0,04558478 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 5,798E-03 0,0454363 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 5,798E-03 0,04528878 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,798E-03 0,04514221 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,798E-03 0,04499659 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,798E-03 0,04485191 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,798E-03 0,04470815 ! spindle assembly GO:0051225 6 5 0,000 5,798E-03 0,04456532 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,798E-03 0,04442339 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,798E-03 0,04428236 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,798E-03 0,04414223 ! drug metabolic process GO:0017144 6 5 0,000 5,798E-03 0,04400298 ! stem cell division GO:0017145 11 5 0,000 5,798E-03 0,0438646 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,798E-03 0,0437271 ! organ regeneration GO:0031100 7 5 0,000 5,798E-03 0,04359045 ! carnitine metabolic process GO:0009437 7 5 0,000 5,798E-03 0,04345465 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 5,798E-03 0,0433197 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,798E-03 0,04318558 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 5,815E-03 0,04318023 ! cell cycle arrest GO:0007050 213 100 1,000 6,047E-03 0,04476653 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,953E-03 0,05131684 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,953E-03 0,05115991 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 6,953E-03 0,05100393 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,953E-03 0,05084891 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,953E-03 0,05069482 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 6,953E-03 0,05054166 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 6,953E-03 0,05038943 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,953E-03 0,05023811 ! sleep GO:0030431 13 6 0,000 6,953E-03 0,05008769 ! response to oxygen radical GO:0000305 11 6 0,000 6,953E-03 0,04993818 ! positive regulation of axon extension GO:0045773 11 6 0,000 6,953E-03 0,04978955 ! myoblast cell fate commitment GO:0048625 16 6 0,000 6,953E-03 0,04964181 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 6,953E-03 0,04949494 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 6,953E-03 0,04934894 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,953E-03 0,04920379 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,953E-03 0,0490595 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 6,953E-03 0,04891605 ! forebrain regionalization GO:0021871 8 6 0,000 6,953E-03 0,04877344 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,953E-03 0,04863166 ! male meiosis GO:0007140 7 6 0,000 6,953E-03 0,0484907 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,953E-03 0,04835055 ! response to zinc ion GO:0010043 9 6 0,000 6,953E-03 0,04821121 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,953E-03 0,04807267 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 6,953E-03 0,04793493 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 6,953E-03 0,04779797 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,953E-03 0,04766179 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,953E-03 0,04752639 ! malate metabolic process GO:0006108 11 6 0,000 6,953E-03 0,04739176 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 6,953E-03 0,04725788 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 6,953E-03 0,04712476 ! protein refolding GO:0042026 15 6 0,000 6,953E-03 0,04699239 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,953E-03 0,04686076 ! opsonization GO:0008228 8 6 0,000 6,953E-03 0,04672986 ! mating behavior GO:0007617 7 6 0,000 6,953E-03 0,04659969 ! neuron remodeling GO:0016322 15 6 0,000 6,953E-03 0,04647025 ! erythrocyte maturation GO:0043249 7 6 0,000 6,953E-03 0,04634152 ! embryonic hemopoiesis GO:0035162 14 6 0,000 6,953E-03 0,04621351 ! equilibrioception GO:0050957 14 6 0,000 6,953E-03 0,0460862 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,953E-03 0,04595959 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 6,953E-03 0,04583367 ! photoreceptor cell development GO:0042461 10 6 0,000 6,953E-03 0,04570844 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,953E-03 0,0455839 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,953E-03 0,04546003 ! response to interferon-gamma GO:0034341 15 6 0,000 6,953E-03 0,04533683 ! toxin metabolic process GO:0009404 11 6 0,000 6,953E-03 0,0452143 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,953E-03 0,04509243 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,953E-03 0,04497121 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 6,953E-03 0,04485064 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 6,953E-03 0,04473072 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 6,953E-03 0,04461144 ! cGMP-mediated signaling GO:0019934 13 6 0,000 6,953E-03 0,04449279 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,953E-03 0,04437477 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 6,953E-03 0,04425738 ! thymic T cell selection GO:0045061 12 6 0,000 6,953E-03 0,04414061 ! protein lipoylation GO:0009249 10 6 0,000 6,953E-03 0,04402445 ! cysteine metabolic process GO:0006534 10 6 0,000 6,953E-03 0,0439089 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,953E-03 0,04379395 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,953E-03 0,04367961 ! glutamate catabolic process GO:0006538 10 6 0,000 6,953E-03 0,04356586 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 6,953E-03 0,0434527 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,953E-03 0,04334013 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 6,953E-03 0,04322814 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 6,953E-03 0,04311673 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,953E-03 0,04300589 ! hyperosmotic response GO:0006972 9 6 0,000 6,953E-03 0,04289562 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 6,953E-03 0,04278591 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 6,953E-03 0,04267676 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,953E-03 0,04256817 ! urea metabolic process GO:0019627 7 6 0,000 6,953E-03 0,04246013 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,953E-03 0,04235263 ! neutrophil activation GO:0042119 8 6 0,000 6,953E-03 0,04224568 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,953E-03 0,04213927 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 6,953E-03 0,04203339 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,953E-03 0,04192805 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,953E-03 0,04182322 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,953E-03 0,04171893 ! neuron apoptosis GO:0051402 9 6 0,000 6,953E-03 0,04161515 ! nucleoside salvage GO:0043174 9 6 0,000 6,953E-03 0,04151189 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 6,953E-03 0,04140913 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,953E-03 0,04130689 ! T cell mediated immunity GO:0002456 16 6 0,000 6,953E-03 0,04120515 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,953E-03 0,04110391 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 6,953E-03 0,04100316 ! carnitine transport GO:0015879 10 6 0,000 6,953E-03 0,04090291 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 6,953E-03 0,04080315 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,953E-03 0,04070387 ! positive regulation of exocytosis GO:0045921 8 6 0,000 6,953E-03 0,04060507 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 6,953E-03 0,04050676 ! 5S class rRNA transcription GO:0042791 11 6 0,000 6,953E-03 0,04040891 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,953E-03 0,04031154 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 6,953E-03 0,04021464 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 6,953E-03 0,0401182 ! sodium ion homeostasis GO:0055078 11 6 0,000 6,953E-03 0,04002222 ! establishment of spindle localization GO:0051293 12 6 0,000 6,953E-03 0,03992671 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,953E-03 0,03983164 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,953E-03 0,03973703 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 6,953E-03 0,03964287 ! neural nucleus development GO:0048857 14 6 0,000 6,953E-03 0,03954915 ! response to UV-C GO:0010225 11 6 0,000 6,953E-03 0,03945587 ! astrocyte development GO:0014002 15 6 0,000 6,953E-03 0,03936304 ! protein targeting to lysosome GO:0006622 10 6 0,000 6,953E-03 0,03927063 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,953E-03 0,03917867 ! interaction with symbiont GO:0051702 13 6 0,000 6,953E-03 0,03908713 ! regulation of dendrite development GO:0050773 16 6 0,000 6,953E-03 0,03899601 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,953E-03 0,03890533 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 6,953E-03 0,03881506 ! response to copper ion GO:0046688 10 6 0,000 6,953E-03 0,03872521 ! response to exogenous dsRNA GO:0043330 10 6 0,000 6,953E-03 0,03863577 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 6,953E-03 0,03854675 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,953E-03 0,03845814 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,953E-03 0,03836993 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,953E-03 0,03828213 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 6,953E-03 0,03819473 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,953E-03 0,03810772 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,953E-03 0,03802111 ! hair follicle maturation GO:0048820 7 6 0,000 6,953E-03 0,0379349 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,953E-03 0,03784907 ! Schwann cell development GO:0014044 15 6 0,000 6,953E-03 0,03776363 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,953E-03 0,03767858 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,953E-03 0,03759391 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 6,953E-03 0,03750962 ! subpallium development GO:0021544 10 6 0,000 6,953E-03 0,0374257 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 6,953E-03 0,03734217 ! histone ubiquitination GO:0016574 8 6 0,000 6,953E-03 0,037259 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 6,953E-03 0,0371762 ! maintenance of organ identity GO:0048496 9 6 0,000 6,953E-03 0,03709377 ! G2 phase GO:0051319 16 6 0,000 6,953E-03 0,0370117 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 6,953E-03 0,03693 ! establishment of planar polarity GO:0001736 7 6 0,000 6,953E-03 0,03684866 ! regulation of mast cell activation GO:0033003 12 6 0,000 6,953E-03 0,03676767 ! membrane to membrane docking GO:0022614 14 6 0,000 6,953E-03 0,03668704 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,953E-03 0,03660676 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 6,953E-03 0,03652683 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,953E-03 0,03644725 ! receptor internalization GO:0031623 10 6 0,000 6,953E-03 0,03636802 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 6,953E-03 0,03628913 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 6,953E-03 0,03621058 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,953E-03 0,03613238 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 6,953E-03 0,0360545 ! protein deubiquitination GO:0016579 14 6 0,000 6,953E-03 0,03597697 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 6,953E-03 0,03589976 ! protein destabilization GO:0031648 9 6 0,000 6,953E-03 0,03582289 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,953E-03 0,03574635 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 6,953E-03 0,03567013 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,953E-03 0,03559423 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 6,953E-03 0,03551866 ! progesterone metabolic process GO:0042448 10 6 0,000 6,953E-03 0,03544341 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 6,953E-03 0,03536848 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 6,953E-03 0,03529386 ! negative regulation of axon extension GO:0030517 21 6 0,000 6,953E-03 0,03521956 ! removal of superoxide radicals GO:0019430 11 6 0,000 6,953E-03 0,03514557 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,953E-03 0,03507189 ! determination of adult lifespan GO:0008340 15 6 0,000 6,953E-03 0,03499851 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 6,953E-03 0,03492545 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 6,953E-03 0,03485269 ! cerebellar cortex formation GO:0021697 8 6 0,000 6,953E-03 0,03478023 ! catecholamine transport GO:0051937 9 6 0,000 6,953E-03 0,03470807 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 6,953E-03 0,03463621 ! sensory cilium assembly GO:0035058 10 6 0,000 6,953E-03 0,03456465 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,953E-03 0,03449338 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 6,953E-03 0,03442241 ! maternal placenta development GO:0001893 12 6 0,000 6,953E-03 0,03435172 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 6,953E-03 0,03428133 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,953E-03 0,03421123 ! negative regulation of B cell activation GO:0050869 13 6 0,000 6,953E-03 0,03414141 ! protein amino acid prenylation GO:0018346 16 6 0,000 6,953E-03 0,03407187 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,953E-03 0,03400262 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 6,953E-03 0,03393365 ! positive regulation of coagulation GO:0050820 12 6 0,000 6,953E-03 0,03386496 ! tRNA transcription GO:0009304 14 7 0,000 8,107E-03 0,03940706 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 8,107E-03 0,03932761 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 8,107E-03 0,03924848 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,107E-03 0,03916967 ! regulation of helicase activity GO:0051095 15 7 0,000 8,107E-03 0,03909118 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 8,107E-03 0,03901299 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 8,107E-03 0,03893512 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,107E-03 0,03885756 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 8,107E-03 0,03878031 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,107E-03 0,03870337 ! prostate gland development GO:0030850 13 7 0,000 8,107E-03 0,03862673 ! nucleotide-sugar transport GO:0015780 12 7 0,000 8,107E-03 0,03855039 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,107E-03 0,03847435 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,107E-03 0,03839862 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 8,107E-03 0,03832318 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,107E-03 0,03824803 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 8,107E-03 0,03817318 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 8,107E-03 0,03809863 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 8,107E-03 0,03802436 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 8,107E-03 0,03795038 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,107E-03 0,03787669 ! SMAD protein complex assembly GO:0007183 12 7 0,000 8,107E-03 0,03780329 ! glycolipid transport GO:0046836 10 7 0,000 8,107E-03 0,03773017 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,107E-03 0,03765733 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,107E-03 0,03758477 ! neuron adhesion GO:0007158 12 7 0,000 8,107E-03 0,03751249 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 8,107E-03 0,03744049 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,107E-03 0,03736877 ! actin-myosin filament sliding GO:0033275 11 7 0,000 8,107E-03 0,03729732 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 8,107E-03 0,03722614 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 8,107E-03 0,03715523 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 8,107E-03 0,03708459 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 8,107E-03 0,03701423 ! mRNA stabilization GO:0048255 18 7 0,000 8,107E-03 0,03694412 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 8,107E-03 0,03687429 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 8,107E-03 0,03680471 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 8,107E-03 0,0367354 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 8,107E-03 0,03666635 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,107E-03 0,03659755 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,107E-03 0,03652902 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,107E-03 0,03646074 ! lipoprotein transport GO:0042953 14 7 0,000 8,107E-03 0,03639272 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,107E-03 0,03632495 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,107E-03 0,03625743 ! rhythmic behavior GO:0007622 15 7 0,000 8,107E-03 0,03619016 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 8,107E-03 0,03612314 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 8,107E-03 0,03605637 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 8,107E-03 0,03598985 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,107E-03 0,03592357 ! regulation of odontogenesis GO:0042481 13 7 0,000 8,107E-03 0,03585753 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,107E-03 0,03579174 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 8,107E-03 0,03572618 ! mechanosensory behavior GO:0007638 14 7 0,000 8,107E-03 0,03566087 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 8,107E-03 0,0355958 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,107E-03 0,03553096 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 8,107E-03 0,03546636 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,107E-03 0,03540199 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,107E-03 0,03533786 ! spinal cord patterning GO:0021511 13 7 0,000 8,107E-03 0,03527395 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 8,107E-03 0,03521028 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,107E-03 0,03514684 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 8,107E-03 0,03508363 ! adrenal gland development GO:0030325 17 7 0,000 8,107E-03 0,03502064 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 8,107E-03 0,03495788 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 8,107E-03 0,03489534 ! ovulation GO:0030728 9 7 0,000 8,107E-03 0,03483303 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 8,107E-03 0,03477094 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 8,107E-03 0,03470907 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 8,107E-03 0,03464742 ! microtubule nucleation GO:0007020 20 7 0,000 8,107E-03 0,03458599 ! proline biosynthetic process GO:0006561 10 7 0,000 8,107E-03 0,03452477 ! thyroid hormone generation GO:0006590 13 7 0,000 8,107E-03 0,03446378 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 8,107E-03 0,03440299 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 8,107E-03 0,03434242 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 8,107E-03 0,03428207 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,107E-03 0,03422192 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,107E-03 0,03416199 ! galactose metabolic process GO:0006012 13 7 0,000 8,107E-03 0,03410227 ! vesicle fusion GO:0006906 17 7 0,000 8,107E-03 0,03404275 ! response to dietary excess GO:0002021 8 7 0,000 8,107E-03 0,03398344 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,107E-03 0,03392434 ! intracellular pH reduction GO:0051452 11 7 0,000 8,107E-03 0,03386545 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,107E-03 0,03380675 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 8,107E-03 0,03374826 ! organ growth GO:0035265 15 7 0,000 8,107E-03 0,03368998 ! purine salvage GO:0043101 10 7 0,000 8,107E-03 0,03363189 ! nucleoside transport GO:0015858 8 7 0,000 8,107E-03 0,033574 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 8,107E-03 0,03351632 ! parturition GO:0007567 14 7 0,000 8,107E-03 0,03345883 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 8,107E-03 0,03340154 ! rRNA modification GO:0000154 14 7 0,000 8,107E-03 0,03334444 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 8,107E-03 0,03328754 ! spindle checkpoint GO:0031577 15 7 0,000 8,107E-03 0,03323083 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 8,107E-03 0,03317431 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 8,107E-03 0,03311799 ! macrophage differentiation GO:0030225 11 7 0,000 8,107E-03 0,03306186 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,107E-03 0,03300592 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,107E-03 0,03295016 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 8,107E-03 0,0328946 ! hyaluronan metabolic process GO:0030212 8 7 0,000 8,107E-03 0,03283922 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 8,107E-03 0,03278403 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,107E-03 0,03272902 ! fibrinolysis GO:0042730 10 7 0,000 8,107E-03 0,0326742 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 8,107E-03 0,03261956 ! eating behavior GO:0042755 7 7 0,000 8,107E-03 0,0325651 ! B cell lineage commitment GO:0002326 21 7 0,000 8,107E-03 0,03251083 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,107E-03 0,03245673 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 8,107E-03 0,03240282 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 8,107E-03 0,03234908 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,107E-03 0,03229552 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 8,107E-03 0,03224214 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,107E-03 0,03218894 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 8,107E-03 0,03213591 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 8,107E-03 0,03208305 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 8,107E-03 0,03203037 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 8,107E-03 0,03197786 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,107E-03 0,03192553 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 8,107E-03 0,03187336 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,107E-03 0,03182137 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,107E-03 0,03176954 ! regulation of meiosis GO:0040020 12 7 0,000 8,107E-03 0,03171788 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 8,107E-03 0,03166639 ! T cell lineage commitment GO:0002360 16 7 0,000 8,107E-03 0,03161507 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 8,107E-03 0,03156391 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,107E-03 0,03151292 ! oxygen homeostasis GO:0032364 12 7 0,000 8,107E-03 0,03146209 ! transcription termination GO:0006353 13 7 0,000 8,107E-03 0,03141143 ! response to tumor cell GO:0002347 13 7 0,000 8,107E-03 0,03136093 ! regulation of respiratory burst GO:0060263 11 7 0,000 8,107E-03 0,03131059 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,107E-03 0,03126041 ! anaphase GO:0051322 17 7 0,000 8,107E-03 0,03121039 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 8,107E-03 0,03116054 ! axonal fasciculation GO:0007413 18 7 0,000 8,107E-03 0,03111084 ! negative regulation of nuclear division GO:0051784 14 7 0,000 8,107E-03 0,0310613 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 8,107E-03 0,03101192 ! peptidyl-threonine modification GO:0018210 25 7 0,000 8,107E-03 0,03096269 ! diuresis GO:0030146 12 7 0,000 8,107E-03 0,03091362 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,107E-03 0,03086471 ! thiamin metabolic process GO:0006772 7 7 0,000 8,107E-03 0,03081595 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,107E-03 0,03076735 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 8,107E-03 0,03071889 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 8,107E-03 0,03067059 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,107E-03 0,03062244 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,107E-03 0,03057445 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,107E-03 0,0305266 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,107E-03 0,0304789 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 8,107E-03 0,03043135 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,107E-03 0,03038395 ! glycolipid catabolic process GO:0019377 15 7 0,000 8,107E-03 0,0303367 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,107E-03 0,03028959 ! lymph node development GO:0048535 10 7 0,000 8,107E-03 0,03024263 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 8,107E-03 0,03019582 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,107E-03 0,03014914 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 8,107E-03 0,03010262 ! endosome to lysosome transport GO:0008333 11 7 0,000 8,107E-03 0,03005624 ! protein modification by small protein removal GO:0070646 16 7 0,000 8,107E-03 0,03001 ! adult feeding behavior GO:0008343 9 7 0,000 8,107E-03 0,0299639 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 8,107E-03 0,02991794 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 8,107E-03 0,02987212 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,107E-03 0,02982645 ! muscle adaptation GO:0043500 14 7 0,000 8,107E-03 0,02978091 ! embryonic heart tube development GO:0035050 10 7 0,000 8,107E-03 0,02973551 ! retina homeostasis GO:0001895 12 7 0,000 8,107E-03 0,02969025 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 8,107E-03 0,02964513 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 8,107E-03 0,02960015 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 8,107E-03 0,0295553 ! protein prenylation GO:0018342 18 7 0,000 8,107E-03 0,02951059 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 8,107E-03 0,02946601 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 8,107E-03 0,02942156 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,107E-03 0,02937725 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 9,26E-03 0,03350461 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 9,26E-03 0,03345431 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 9,26E-03 0,03340415 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 9,26E-03 0,03335414 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 9,26E-03 0,03330429 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,26E-03 0,03325458 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,26E-03 0,03320502 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 9,26E-03 0,03315561 ! neutral lipid catabolic process GO:0046461 13 8 0,000 9,26E-03 0,03310634 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 9,26E-03 0,03305722 ! meiotic prophase I GO:0007128 13 8 0,000 9,26E-03 0,03300825 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,26E-03 0,03295942 ! oligopeptide transport GO:0006857 15 8 0,000 9,26E-03 0,03291074 ! UTP metabolic process GO:0046051 8 8 0,000 9,26E-03 0,03286219 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 9,26E-03 0,0328138 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 9,26E-03 0,03276554 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 9,26E-03 0,03271743 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,26E-03 0,03266945 ! succinate metabolic process GO:0006105 14 8 0,000 9,26E-03 0,03262162 ! membrane hyperpolarization GO:0060081 10 8 0,000 9,26E-03 0,03257393 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,26E-03 0,03252638 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 9,26E-03 0,03247896 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,26E-03 0,03243169 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 9,26E-03 0,03238455 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,26E-03 0,03233754 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,26E-03 0,03229068 ! ganglioside metabolic process GO:0001573 19 8 0,000 9,26E-03 0,03224395 ! reflex GO:0060004 16 8 0,000 9,26E-03 0,03219735 ! negative regulation of endocytosis GO:0045806 11 8 0,000 9,26E-03 0,03215089 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 9,26E-03 0,03210456 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,26E-03 0,03205837 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 9,26E-03 0,03201231 ! glycerolipid catabolic process GO:0046503 13 8 0,000 9,26E-03 0,03196638 ! hemoglobin metabolic process GO:0020027 13 8 0,000 9,26E-03 0,03192058 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,26E-03 0,03187492 ! pigment granule organization GO:0048753 16 8 0,000 9,26E-03 0,03182938 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,26E-03 0,03178398 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 9,26E-03 0,0317387 ! astrocyte differentiation GO:0048708 18 8 0,000 9,26E-03 0,03169355 ! histidine metabolic process GO:0006547 16 8 0,000 9,26E-03 0,03164853 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,26E-03 0,03160364 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 9,26E-03 0,03155888 ! glycine catabolic process GO:0006546 13 8 0,000 9,26E-03 0,03151424 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 9,26E-03 0,03146973 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 9,26E-03 0,03142534 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 9,26E-03 0,03138108 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 9,26E-03 0,03133694 ! regulation of pigmentation during development GO:0048070 24 8 0,000 9,26E-03 0,03129293 ! melanin metabolic process GO:0006582 15 8 0,000 9,26E-03 0,03124904 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 9,26E-03 0,03120528 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 9,26E-03 0,03116163 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,26E-03 0,03111811 ! macrophage activation GO:0042116 12 8 0,000 9,26E-03 0,03107471 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,26E-03 0,03103143 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,26E-03 0,03098827 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 9,26E-03 0,03094523 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,26E-03 0,03090231 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 9,26E-03 0,03085951 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 9,26E-03 0,03081683 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,26E-03 0,03077426 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 9,26E-03 0,03073182 ! osteoblast development GO:0002076 16 8 0,000 9,26E-03 0,03068949 ! positive regulation of vasodilation GO:0045909 13 8 0,000 9,26E-03 0,03064727 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 9,26E-03 0,03060518 ! negative regulation of translational initiation GO:0045947 10 8 0,000 9,26E-03 0,03056319 ! Schwann cell differentiation GO:0014037 19 8 0,000 9,26E-03 0,03052133 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 9,26E-03 0,03047957 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,26E-03 0,03043793 ! response to UV-B GO:0010224 16 8 0,000 9,26E-03 0,03039641 ! protein targeting to vacuole GO:0006623 12 8 0,000 9,26E-03 0,030355 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,26E-03 0,0303137 ! intermediate filament organization GO:0045109 12 8 0,000 9,26E-03 0,03027251 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 9,26E-03 0,03023144 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 9,26E-03 0,03019047 ! cellular extravasation GO:0045123 12 8 0,000 9,26E-03 0,03014962 ! cardiac muscle cell development GO:0055013 13 8 0,000 9,26E-03 0,03010888 ! regulation of circadian rhythm GO:0042752 16 8 0,000 9,26E-03 0,03006824 ! response to antibiotic GO:0046677 11 8 0,000 9,26E-03 0,03002772 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 9,26E-03 0,02998731 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 9,26E-03 0,029947 ! DNA topological change GO:0006265 12 8 0,000 9,26E-03 0,0299068 ! response to tropane GO:0014073 15 8 0,000 9,26E-03 0,02986671 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 9,26E-03 0,02982673 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 9,26E-03 0,02978686 ! melanosome transport GO:0032402 13 8 0,000 9,26E-03 0,02974709 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 9,26E-03 0,02970742 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 9,26E-03 0,02966787 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,26E-03 0,02962841 ! mast cell activation GO:0045576 14 8 0,000 9,26E-03 0,02958907 ! multicellular organismal aging GO:0010259 18 8 0,000 9,26E-03 0,02954982 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 9,26E-03 0,02951069 ! dendrite morphogenesis GO:0048813 13 8 0,000 9,26E-03 0,02947165 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 9,26E-03 0,02943272 ! nucleosome disassembly GO:0006337 14 8 0,000 9,26E-03 0,02939389 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,26E-03 0,02935516 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 9,26E-03 0,02931654 ! leukocyte activation during immune response GO:0002366 13 8 0,000 9,26E-03 0,02927801 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,26E-03 0,02923959 ! establishment of chromosome localization GO:0051303 12 8 0,000 9,26E-03 0,02920127 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 9,26E-03 0,02916305 ! intracellular lipid transport GO:0032365 13 8 0,000 9,26E-03 0,02912493 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,26E-03 0,0290869 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 9,26E-03 0,02904898 ! regulation of macrophage activation GO:0043030 15 8 0,000 9,26E-03 0,02901116 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 9,26E-03 0,02897343 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,26E-03 0,0289358 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 9,26E-03 0,02889827 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 9,26E-03 0,02886084 ! hormone catabolic process GO:0042447 17 8 0,000 9,26E-03 0,0288235 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,26E-03 0,02878626 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 9,26E-03 0,02874912 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 9,26E-03 0,02871207 ! ATP catabolic process GO:0006200 11 8 0,000 9,26E-03 0,02867512 ! blastocyst growth GO:0001832 19 8 0,000 9,26E-03 0,02863826 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,26E-03 0,0286015 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,26E-03 0,02856483 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 9,26E-03 0,02852826 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,26E-03 0,02849177 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 9,26E-03 0,02845539 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 9,26E-03 0,02841909 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 9,26E-03 0,02838289 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 9,26E-03 0,02834678 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 9,26E-03 0,02831076 ! amino sugar catabolic process GO:0046348 10 8 0,000 9,26E-03 0,02827483 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 9,26E-03 0,028239 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,26E-03 0,02820325 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 9,26E-03 0,02816759 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,26E-03 0,02813203 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,26E-03 0,02809655 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,26E-03 0,02806117 ! NAD biosynthetic process GO:0009435 13 8 0,000 9,26E-03 0,02802587 ! regulation of developmental growth GO:0048638 15 9 0,000 0,0104121 0,03147174 ! axon extension GO:0048675 15 9 0,000 0,0104121 0,03143225 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0104121 0,03139286 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0104121 0,03135357 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0104121 0,03131438 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0104121 0,03127529 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0104121 0,03123629 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0104121 0,03119739 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0104121 0,03115859 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0104121 0,03111988 ! phosphate transport GO:0006817 19 9 0,000 0,0104121 0,03108127 ! reproductive behavior GO:0019098 19 9 0,000 0,0104121 0,03104276 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0104121 0,03100434 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0104121 0,03096601 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0104121 0,03092779 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0104121 0,03088965 ! GTP metabolic process GO:0046039 9 9 0,000 0,0104121 0,03085161 ! RNA methylation GO:0001510 15 9 0,000 0,0104121 0,03081366 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0104121 0,03077581 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0104121 0,03073804 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0104121 0,03070037 ! artery development GO:0060840 24 9 0,000 0,0104121 0,0306628 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0104121 0,03062531 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0104121 0,03058792 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0104121 0,03055062 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0104121 0,03051341 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0104121 0,03047628 ! chemosensory behavior GO:0007635 20 9 0,000 0,0104121 0,03043925 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0104121 0,03040231 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0104121 0,03036546 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0104121 0,0303287 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0104121 0,03029203 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0104121 0,03025544 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0104121 0,03021895 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0104121 0,03018254 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0104121 0,03014622 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0104121 0,03010998 ! protein targeting to ER GO:0045047 22 9 0,000 0,0104121 0,03007384 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0104121 0,03003778 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0104121 0,0300018 ! T cell selection GO:0045058 23 9 0,000 0,0104121 0,02996592 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,0104121 0,02993011 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0104121 0,0298944 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0104121 0,02985877 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0104121 0,02982322 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0104121 0,02978776 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0104121 0,02975238 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0104121 0,02971709 ! mannose metabolic process GO:0006013 13 9 0,000 0,0104121 0,02968188 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0104121 0,02964675 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0104121 0,02961171 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0104121 0,02957675 ! receptor clustering GO:0043113 18 9 0,000 0,0104121 0,02954187 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0104121 0,02950707 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0104121 0,02947236 ! ruffle organization GO:0031529 15 9 0,000 0,0104121 0,02943773 ! retinol metabolic process GO:0042572 18 9 0,000 0,0104121 0,02940318 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0104121 0,02936871 ! behavioral fear response GO:0001662 22 9 0,000 0,0104121 0,02933432 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0104121 0,02930001 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0104121 0,02926578 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0104121 0,02923163 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0104121 0,02919756 ! protein heterooligomerization GO:0051291 16 9 0,000 0,0104121 0,02916357 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0104121 0,02912966 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0104121 0,02909583 ! segment specification GO:0007379 13 9 0,000 0,0104121 0,02906207 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0104121 0,0290284 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0104121 0,0289948 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0104121 0,02896128 ! response to amine stimulus GO:0014075 13 9 0,000 0,0104121 0,02892784 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0104121 0,02889447 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0104121 0,02886118 ! erythrocyte development GO:0048821 15 9 0,000 0,0104121 0,02882797 ! gas homeostasis GO:0033483 16 9 0,000 0,0104121 0,02879483 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0104121 0,02876177 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0104121 0,02872879 ! renal water homeostasis GO:0003091 14 9 0,000 0,0104121 0,02869588 ! postreplication repair GO:0006301 22 9 0,000 0,0104121 0,02866305 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0104121 0,02863029 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0104121 0,02859761 ! icosanoid secretion GO:0032309 15 9 0,000 0,0104121 0,028565 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0104121 0,02853247 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0104121 0,02850001 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0104121 0,02846762 ! regulation of cell division GO:0051302 15 9 0,000 0,0104121 0,02843531 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0104121 0,02840307 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0104121 0,0283709 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0104121 0,02833881 ! sterol catabolic process GO:0016127 11 9 0,000 0,0104121 0,02830679 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0104121 0,02827484 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0104121 0,02824296 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0104121 0,02821116 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0104121 0,02817942 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0104121 0,02814776 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0104121 0,02811617 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0104121 0,02808465 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0104121 0,0280532 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0104121 0,02802182 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0104121 0,02799051 ! purine base metabolic process GO:0006144 21 9 0,000 0,0104121 0,02795927 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0104121 0,0279281 ! pigment granule transport GO:0051904 17 9 0,000 0,0104121 0,027897 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0104121 0,02786597 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0104121 0,02783501 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0104121 0,02780411 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0104121 0,02777329 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0104121 0,02774253 ! mitochondrion localization GO:0051646 15 9 0,000 0,0104121 0,02771184 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01156248 0,03073957 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01156248 0,03070565 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01156248 0,03067179 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01156248 0,03063801 ! synapsis GO:0007129 13 10 0,000 0,01156248 0,03060431 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01156248 0,03057068 ! N-glycan processing GO:0006491 20 10 0,000 0,01156248 0,03053712 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01156248 0,03050363 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01156248 0,03047022 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01156248 0,03043689 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01156248 0,03040362 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01156248 0,03037043 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01156248 0,03033731 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01156248 0,03030426 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01156248 0,03027129 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01156248 0,03023839 ! androgen metabolic process GO:0008209 17 10 0,000 0,01156248 0,03020555 ! phospholipid efflux GO:0033700 16 10 0,000 0,01156248 0,03017279 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01156248 0,0301401 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01156248 0,03010748 ! lung alveolus development GO:0048286 26 10 0,000 0,01156248 0,03007494 ! pathogenesis GO:0009405 13 10 0,000 0,01156248 0,03004246 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01156248 0,03001005 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01156248 0,02997771 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01156248 0,02994544 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01156248 0,02991324 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01156248 0,02988111 ! endoderm development GO:0007492 16 10 0,000 0,01156248 0,02984905 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01156248 0,02981706 ! arginine catabolic process GO:0006527 13 10 0,000 0,01156248 0,02978513 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01156248 0,02975328 ! proline metabolic process GO:0006560 13 10 0,000 0,01156248 0,02972149 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01156248 0,02968977 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01156248 0,02965812 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01156248 0,02962653 ! V(D)J recombination GO:0033151 28 10 0,000 0,01156248 0,02959502 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01156248 0,02956357 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01156248 0,02953218 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01156248 0,02950086 ! B cell proliferation GO:0042100 18 10 0,000 0,01156248 0,02946961 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01156248 0,02943843 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01156248 0,02940731 ! multicellular organism growth GO:0035264 18 10 0,000 0,01156248 0,02937626 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01156248 0,02934527 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01156248 0,02931435 ! epithelial cell development GO:0002064 20 10 0,000 0,01156248 0,02928349 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01156248 0,0292527 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01156248 0,02922197 ! macroautophagy GO:0016236 17 10 0,000 0,01156248 0,02919131 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01156248 0,02916071 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01156248 0,02913017 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01156248 0,0290997 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01156248 0,02906929 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01156248 0,02903895 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01156248 0,02900867 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01156248 0,02897845 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01156248 0,0289483 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01156248 0,02891821 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01156248 0,02888818 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01156248 0,02885821 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01156248 0,02882831 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01156248 0,02879846 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01156248 0,02876868 ! response to dsRNA GO:0043331 20 10 0,000 0,01156248 0,02873896 ! DNA ligation GO:0006266 19 10 0,000 0,01156248 0,0287093 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01156248 0,02867971 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01156248 0,02865017 ! melanosome localization GO:0032400 16 10 0,000 0,01156248 0,02862069 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01156248 0,02859128 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01156248 0,02856193 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01156248 0,02853263 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01156248 0,0285034 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01156248 0,02847422 ! protein sumoylation GO:0016925 15 10 0,000 0,01156248 0,02844511 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01156248 0,02841605 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01156248 0,02838706 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01156248 0,02835812 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01156248 0,02832924 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01156248 0,02830042 ! salivary gland development GO:0007431 27 10 0,000 0,01156248 0,02827166 ! prophase GO:0051324 15 10 0,000 0,01156248 0,02824296 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01156248 0,02821432 ! apical protein localization GO:0045176 15 10 0,000 0,01156248 0,02818573 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01156248 0,0281572 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01156248 0,02812873 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01156248 0,02810032 ! midbrain development GO:0030901 13 10 0,000 0,01156248 0,02807196 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01156248 0,02804366 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01156248 0,02801542 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01156248 0,02798724 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01156248 0,02795911 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01156248 0,02793104 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01156248 0,02790302 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01156248 0,02787507 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01156248 0,02784716 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01156248 0,02781932 ! oocyte development GO:0048599 17 10 0,000 0,01156248 0,02779152 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01156248 0,02776379 ! blastocyst formation GO:0001825 17 10 0,000 0,01156248 0,02773611 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01156248 0,02770848 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01156248 0,02768091 ! activation of innate immune response GO:0002218 12 10 0,000 0,01156248 0,02765339 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01156248 0,02762593 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01156248 0,02759853 ! response to nicotine GO:0035094 20 10 0,000 0,01156248 0,02757117 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01156248 0,02754388 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01156248 0,02751663 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01156248 0,02748944 ! localization within membrane GO:0051668 20 10 0,000 0,01156248 0,02746231 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01271155 0,03016173 ! respiratory burst GO:0045730 17 11 0,000 0,01271155 0,03013202 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01271155 0,03010236 ! neuron fate specification GO:0048665 17 11 0,000 0,01271155 0,03007276 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01271155 0,03004322 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01271155 0,03001374 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01271155 0,02998431 ! thyroid gland development GO:0030878 26 11 0,000 0,01271155 0,02995494 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01271155 0,02992563 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01271155 0,02989638 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01271155 0,02986719 ! response to pain GO:0048265 24 11 0,000 0,01271155 0,02983805 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01271155 0,02980897 ! T cell proliferation GO:0042098 26 11 0,000 0,01271155 0,02977994 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01271155 0,02975097 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01271155 0,02972206 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01271155 0,0296932 ! bone resorption GO:0045453 16 11 0,000 0,01271155 0,0296644 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01271155 0,02963566 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01271155 0,02960697 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01271155 0,02957834 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01271155 0,02954976 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01271155 0,02952123 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01271155 0,02949277 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01271155 0,02946435 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01271155 0,02943599 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01271155 0,02940769 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01271155 0,02937944 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01271155 0,02935125 ! lipid digestion GO:0044241 18 11 0,000 0,01271155 0,0293231 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01271155 0,02929502 ! UV protection GO:0009650 19 11 0,000 0,01271155 0,02926698 ! adult heart development GO:0007512 14 11 0,000 0,01271155 0,029239 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01271155 0,02921108 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01271155 0,0291832 ! temperature homeostasis GO:0001659 17 11 0,000 0,01271155 0,02915538 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01271155 0,02912762 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01271155 0,0290999 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01271155 0,02907224 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01271155 0,02904463 ! regulation of organ growth GO:0046620 13 11 0,000 0,01271155 0,02901708 ! pigment granule localization GO:0051875 20 11 0,000 0,01271155 0,02898957 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01271155 0,02896212 ! vasoconstriction GO:0042310 18 11 0,000 0,01271155 0,02893472 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01271155 0,02890737 ! embryonic axis specification GO:0000578 18 11 0,000 0,01271155 0,02888007 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01271155 0,02885283 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01271155 0,02882563 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01271155 0,02879849 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01271155 0,0287714 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01271155 0,02874436 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01271155 0,02871737 ! zymogen activation GO:0031638 15 11 0,000 0,01271155 0,02869043 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01271155 0,02866354 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01271155 0,0286367 ! nucleosome positioning GO:0016584 15 11 0,000 0,01271155 0,02860991 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01271155 0,02858318 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01271155 0,02855649 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01271155 0,02852985 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01271155 0,02850326 ! acid secretion GO:0046717 18 11 0,000 0,01271155 0,02847672 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01271155 0,02845023 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01271155 0,02842379 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01271155 0,0283974 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01271155 0,02837106 ! oocyte differentiation GO:0009994 18 11 0,000 0,01271155 0,02834476 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01271155 0,02831852 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,01271155 0,02829232 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01271155 0,02826617 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01271155 0,02824007 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01271155 0,02821402 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01271155 0,02818802 ! embryonic gut development GO:0048566 15 11 0,000 0,01271155 0,02816206 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01271155 0,02813615 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01271155 0,02811029 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01271155 0,02808448 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01271155 0,02805871 ! defense response to fungus GO:0050832 13 11 0,000 0,01271155 0,028033 ! developmental induction GO:0031128 19 11 0,000 0,01271155 0,02800732 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01271155 0,0279817 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01271155 0,02795612 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01271155 0,02793059 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01271155 0,02790511 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01271155 0,02787967 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01271155 0,02785428 ! nucleus localization GO:0051647 19 11 0,000 0,01271155 0,02782893 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01271155 0,02780363 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01385933 0,03028661 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01385933 0,03025913 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01385933 0,0302317 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01385933 0,03020431 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01385933 0,03017698 ! virus-host interaction GO:0019048 29 12 0,000 0,01385933 0,03014969 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01385933 0,03012246 ! cartilage condensation GO:0001502 20 12 0,000 0,01385933 0,03009527 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01385933 0,03006813 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01385933 0,03004104 ! protein complex disassembly GO:0043241 27 12 0,000 0,01385933 0,03001401 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01385933 0,02998701 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01385933 0,02996007 ! hippocampus development GO:0021766 26 12 0,000 0,01385933 0,02993318 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01385933 0,02990633 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01385933 0,02987953 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01385933 0,02985278 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01385933 0,02982608 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01385933 0,02979943 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01385933 0,02977282 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01385933 0,02974626 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01385933 0,02971975 ! drug transport GO:0015893 16 12 0,000 0,01385933 0,02969329 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01385933 0,02966687 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01385933 0,0296405 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01385933 0,02961417 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01385933 0,0295879 ! focal adhesion formation GO:0048041 35 12 0,000 0,01385933 0,02956167 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01385933 0,02953548 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01385933 0,02950934 ! forebrain cell migration GO:0021885 21 12 0,000 0,01385933 0,02948325 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01385933 0,02945721 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01385933 0,02943121 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01385933 0,02940526 ! entry into host cell GO:0030260 32 12 0,000 0,01385933 0,02937935 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01385933 0,02935349 ! monoamine transport GO:0015844 18 12 0,000 0,01385933 0,02932767 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01385933 0,0293019 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01385933 0,02927617 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01385933 0,02925049 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01385933 0,02922486 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01385933 0,02919926 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01385933 0,02917372 ! protein homotetramerization GO:0051289 21 12 0,000 0,01385933 0,02914822 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01385933 0,02912276 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01385933 0,02909735 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01385933 0,02907198 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01385933 0,02904665 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01385933 0,02902137 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01385933 0,02899614 ! cranial nerve development GO:0021545 20 12 0,000 0,01385933 0,02897095 ! fucose catabolic process GO:0019317 22 12 0,000 0,01385933 0,0289458 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01385933 0,02892069 ! histone acetylation GO:0016573 26 12 0,000 0,01385933 0,02889563 ! histone methylation GO:0016571 26 12 0,000 0,01385933 0,02887061 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01385933 0,02884564 ! gland morphogenesis GO:0022612 29 12 0,000 0,01385933 0,02882071 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01385933 0,02879582 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01385933 0,02877097 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01385933 0,02874617 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01385933 0,02872141 ! spleen development GO:0048536 22 12 0,000 0,01385933 0,0286967 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01385933 0,02867202 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01385933 0,02864739 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01385933 0,0286228 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01385933 0,02859825 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01385933 0,02857374 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01385933 0,02854928 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01385933 0,02852486 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01385933 0,02850048 ! response to cold GO:0009409 17 12 0,000 0,01385933 0,02847614 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01385933 0,02845184 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01385933 0,02842759 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01500582 0,03075298 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01500582 0,03072681 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01500582 0,03070068 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01500582 0,0306746 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01500582 0,03064856 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01500582 0,03062256 ! lipid localization GO:0010876 28 13 0,000 0,01500582 0,03059661 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01500582 0,0305707 ! organelle fusion GO:0048284 32 13 0,000 0,01500582 0,03054484 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01500582 0,03051902 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01500582 0,03049324 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01500582 0,03046751 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01500582 0,03044182 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01500582 0,03041618 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01500582 0,03039057 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01500582 0,03036501 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01500582 0,0303395 ! methionine metabolic process GO:0006555 27 13 0,000 0,01500582 0,03031402 ! plasma membrane organization GO:0007009 24 13 0,000 0,01500582 0,03028859 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01500582 0,0302632 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01500582 0,03023786 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01500582 0,03021255 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01500582 0,03018729 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01500582 0,03016207 ! response to X-ray GO:0010165 25 13 0,000 0,01500582 0,0301369 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01500582 0,03011176 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01500582 0,03008667 ! exocrine system development GO:0035272 32 13 0,000 0,01500582 0,03006162 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01500582 0,03003661 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01500582 0,03001164 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01500582 0,02998671 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01500582 0,02996183 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01500582 0,02993698 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01500582 0,02991218 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01500582 0,02988742 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01500582 0,0298627 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01500582 0,02983802 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01500582 0,02981338 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01500582 0,02978878 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01500582 0,02976422 ! ribosome assembly GO:0042255 17 13 0,000 0,01500582 0,02973971 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01500582 0,02971523 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01500582 0,02969079 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01500582 0,02966639 ! chromatin silencing GO:0006342 26 13 0,000 0,01500582 0,02964204 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01500582 0,02961772 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01500582 0,02959344 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01500582 0,02956921 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01500582 0,02954501 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01500582 0,02952085 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01500582 0,02949673 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01500582 0,02947265 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01500582 0,02944861 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01500582 0,02942461 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01500582 0,02940065 ! embryonic placenta development GO:0001892 23 13 0,000 0,01500582 0,02937673 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01500582 0,02935285 ! insulin secretion GO:0030073 23 13 0,000 0,01500582 0,029329 ! actin filament polymerization GO:0030041 24 13 0,000 0,01500582 0,0293052 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01500582 0,02928143 ! acrosome reaction GO:0007340 18 13 0,000 0,01500582 0,0292577 ! rRNA transcription GO:0009303 25 14 0,000 0,01615101 0,03146504 ! lactation GO:0007595 26 14 0,000 0,01615101 0,03143959 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01615101 0,03141417 ! reproductive cellular process GO:0048610 20 14 0,000 0,01615101 0,0313888 ! tRNA modification GO:0006400 20 14 0,000 0,01615101 0,03136346 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01615101 0,03133817 ! regulation of S phase GO:0033261 23 14 0,000 0,01615101 0,03131292 ! water transport GO:0006833 21 14 0,000 0,01615101 0,0312877 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01615101 0,03126253 ! non-recombinational repair GO:0000726 25 14 0,000 0,01615101 0,0312374 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01615101 0,03121231 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01615101 0,03118726 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01615101 0,03116225 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01615101 0,03113728 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01615101 0,03111235 ! palate development GO:0060021 31 14 0,000 0,01615101 0,03108746 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01615101 0,03106261 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01615101 0,0310378 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01615101 0,03101303 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01615101 0,0309883 ! arginine metabolic process GO:0006525 17 14 0,000 0,01615101 0,03096361 ! regulation of heart rate GO:0002027 24 14 0,000 0,01615101 0,03093896 ! organic alcohol transport GO:0015850 29 14 0,000 0,01615101 0,03091434 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01615101 0,03088977 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01615101 0,03086523 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01615101 0,03084074 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01615101 0,03081628 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01615101 0,03079186 ! L-amino acid transport GO:0015807 30 14 0,000 0,01615101 0,03076748 ! bone mineralization GO:0030282 17 14 0,000 0,01615101 0,03074314 ! stem cell development GO:0048864 43 14 0,000 0,01615101 0,03071884 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01615101 0,03069457 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01615101 0,03067035 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01615101 0,03064616 ! cerebellum development GO:0021549 21 14 0,000 0,01615101 0,03062201 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01615101 0,0305979 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01615101 0,03057382 ! response to gamma radiation GO:0010332 28 14 0,000 0,01615101 0,03054979 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01615101 0,03052579 ! cofactor transport GO:0051181 26 14 0,000 0,01615101 0,03050183 ! NADP metabolic process GO:0006739 24 14 0,000 0,01615101 0,0304779 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01615101 0,03045402 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01615101 0,03043017 ! intestinal absorption GO:0050892 25 14 0,000 0,01615101 0,03040636 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01615101 0,03038259 ! oxygen transport GO:0015671 21 14 0,000 0,01615101 0,03035885 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01615101 0,03033515 ! male genitalia development GO:0030539 24 14 0,000 0,01615101 0,03031149 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01615101 0,03028786 ! regulation of axon extension GO:0030516 37 14 0,000 0,01615101 0,03026427 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01615101 0,03024072 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01615101 0,03021721 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01729491 0,0323322 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01729491 0,0323071 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01729491 0,03228204 ! superoxide anion generation GO:0042554 20 15 0,000 0,01729491 0,03225701 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01729491 0,03223202 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01729491 0,03220708 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01729491 0,03218217 ! copper ion transport GO:0006825 20 15 0,000 0,01729491 0,0321573 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01729491 0,03213247 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01729491 0,03210767 ! sulfate transport GO:0008272 23 15 0,000 0,01729491 0,03208292 ! response to cAMP GO:0051591 22 15 0,000 0,01729491 0,0320582 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01729491 0,03203352 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01729491 0,03200888 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01729491 0,03198428 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01729491 0,03195971 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01729491 0,03193518 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01729491 0,03191069 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01729491 0,03188624 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01729491 0,03186183 ! pituitary gland development GO:0021983 29 15 0,000 0,01729491 0,03183745 ! vesicle coating GO:0006901 33 15 0,000 0,01729491 0,03181311 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01729491 0,0317888 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01729491 0,03176454 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01729491 0,03174031 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01729491 0,03171612 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01729491 0,03169196 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01729491 0,03166784 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01729491 0,03164376 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01729491 0,03161971 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01729491 0,03159571 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01729491 0,03157173 ! histone deacetylation GO:0016575 20 15 0,000 0,01729491 0,0315478 ! tissue regeneration GO:0042246 26 15 0,000 0,01729491 0,0315239 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01729491 0,03150003 ! water homeostasis GO:0030104 27 15 0,000 0,01729491 0,03147621 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01729491 0,03145241 ! muscle maintenance GO:0046716 26 15 0,000 0,01729491 0,03142866 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01729491 0,03140494 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01729491 0,03138125 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01729491 0,03135761 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01729491 0,03133399 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01729491 0,03131042 ! cell killing GO:0001906 29 15 0,000 0,01729491 0,03128687 ! detection of bacterium GO:0016045 18 15 0,000 0,01729491 0,03126337 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01729491 0,0312399 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01729491 0,03121646 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01729491 0,03119306 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01729491 0,0311697 ! peptide hormone processing GO:0016486 23 15 0,000 0,01729491 0,03114636 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01843751 0,03317924 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01843751 0,03315445 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01843751 0,03312969 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01843751 0,03310496 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01843751 0,03308028 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01843751 0,03305563 ! bone remodeling GO:0046849 27 16 0,000 0,01843751 0,03303101 ! filopodium assembly GO:0046847 32 16 0,000 0,01843751 0,03300644 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01843751 0,0329819 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01843751 0,03295739 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01843751 0,03293292 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01843751 0,03290849 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01843751 0,0328841 ! startle response GO:0001964 28 16 0,000 0,01843751 0,03285974 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01843751 0,03283542 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01843751 0,03281113 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01843751 0,03278688 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01843751 0,03276267 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01843751 0,03273849 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01843751 0,03271434 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01843751 0,03269024 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01843751 0,03266616 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01843751 0,03264213 ! response to osmotic stress GO:0006970 25 16 0,000 0,01843751 0,03261812 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01843751 0,03259416 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01843751 0,03257023 ! fructose metabolic process GO:0006000 25 16 0,000 0,01843751 0,03254633 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01843751 0,03252247 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01843751 0,03249864 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01843751 0,03247485 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01843751 0,0324511 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01843751 0,03242738 ! axon cargo transport GO:0008088 43 16 0,000 0,01843751 0,03240369 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01843751 0,03238004 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01843751 0,03235642 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01843751 0,03233284 ! neuron recognition GO:0008038 35 16 0,000 0,01843751 0,03230929 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01843751 0,03228577 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01843751 0,03226229 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01843751 0,03223884 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01843751 0,03221543 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01843751 0,03219205 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01843751 0,03216871 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01843751 0,0321454 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01843751 0,03212212 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01843751 0,03209888 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01843751 0,03207567 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01843751 0,03205249 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01843751 0,03202935 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01843751 0,03200624 ! defense response to virus GO:0051607 37 16 0,000 0,01843751 0,03198316 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01957882 0,03393851 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01957882 0,03391408 ! metencephalon development GO:0022037 30 17 0,000 0,01957882 0,03388968 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01957882 0,03386531 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01957882 0,03384098 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01957882 0,03381669 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01957882 0,03379243 ! signal complex assembly GO:0007172 41 17 0,000 0,01957882 0,03376821 ! endothelial cell migration GO:0043542 28 17 0,000 0,01957882 0,03374402 ! inositol metabolic process GO:0006020 28 17 0,000 0,01957882 0,03371986 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01957882 0,03369574 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01957882 0,03367166 ! glial cell development GO:0021782 27 17 0,000 0,01957882 0,03364761 ! limbic system development GO:0021761 36 17 0,000 0,01957882 0,03362359 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01957882 0,03359961 ! adult walking behavior GO:0007628 33 17 0,000 0,01957882 0,03357566 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01957882 0,03355175 ! heart looping GO:0001947 30 17 0,000 0,01957882 0,03352787 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01957882 0,03350402 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01957882 0,03348021 ! myoblast differentiation GO:0045445 45 17 0,000 0,01957882 0,03345643 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01957882 0,03343268 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01957882 0,03340897 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01957882 0,03338529 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01957882 0,03336165 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01957882 0,03333804 ! glycine metabolic process GO:0006544 28 17 0,000 0,01957882 0,03331446 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01957882 0,03329092 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01957882 0,03326741 ! NAD metabolic process GO:0019674 29 17 0,000 0,01957882 0,03324393 ! membrane budding GO:0006900 37 17 0,000 0,01957882 0,03322049 ! DNA integration GO:0015074 29 17 0,000 0,01957882 0,03319708 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01957882 0,0331737 ! regulation of protein binding GO:0043393 33 17 0,000 0,01957882 0,03315035 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01957882 0,03312704 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01957882 0,03310376 ! genitalia development GO:0048806 30 17 0,000 0,01957882 0,03308051 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01957882 0,0330573 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01957882 0,03303412 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01957882 0,03301097 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01957882 0,03298785 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01957882 0,03296477 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01957882 0,03294171 ! steroid catabolic process GO:0006706 31 17 0,000 0,01957882 0,03291869 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01957882 0,03289571 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01957882 0,03287275 ! gas transport GO:0015669 25 17 0,000 0,01957882 0,03284983 ! organic cation transport GO:0015695 31 17 0,000 0,01957882 0,03282693 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01957882 0,03280407 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01957882 0,03278125 ! microspike assembly GO:0030035 36 17 0,000 0,01957882 0,03275845 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01957882 0,03273569 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01957882 0,03271295 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02071885 0,03459372 ! neuron maturation GO:0042551 42 18 0,000 0,02071885 0,03456973 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02071885 0,03454577 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02071885 0,03452185 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02071885 0,03449796 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02071885 0,0344741 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02071885 0,03445028 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02071885 0,03442648 ! memory GO:0007613 31 18 0,000 0,02071885 0,03440273 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02071885 0,034379 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02071885 0,03435531 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02071885 0,03433165 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02071885 0,03430802 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02071885 0,03428442 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02071885 0,03426086 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02071885 0,03423733 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02071885 0,03421383 ! response to retinoic acid GO:0032526 26 18 0,000 0,02071885 0,03419036 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02071885 0,03416693 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02071885 0,03414353 ! response to fungus GO:0009620 21 18 0,000 0,02071885 0,03412016 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02071885 0,03409682 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02071885 0,03407351 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02071885 0,03405024 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02071885 0,034027 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02071885 0,03400379 ! vitamin transport GO:0051180 27 18 0,000 0,02071885 0,03398061 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02071885 0,03395746 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02071885 0,03393434 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02071885 0,03391126 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02071885 0,03388821 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02071885 0,03386518 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02071885 0,03384219 ! nerve development GO:0021675 28 18 0,000 0,02071885 0,03381923 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02071885 0,03379631 ! protein secretion GO:0009306 39 19 0,000 0,02185759 0,03562964 ! positive regulation of translation GO:0045727 30 19 0,000 0,02185759 0,03560552 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02185759 0,03558143 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02185759 0,03555737 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02185759 0,03553335 ! skin development GO:0043588 36 19 0,000 0,02185759 0,03550935 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02185759 0,03548539 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02185759 0,03546146 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02185759 0,03543757 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02185759 0,0354137 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02185759 0,03538987 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02185759 0,03536607 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02185759 0,03534231 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02185759 0,03531857 ! cerebral cortex development GO:0021987 36 19 0,000 0,02185759 0,03529487 ! pigmentation during development GO:0048066 41 19 0,000 0,02185759 0,03527119 ! response to vitamin A GO:0033189 27 19 0,000 0,02185759 0,03524755 ! heme metabolic process GO:0042168 36 19 0,000 0,02185759 0,03522395 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02185759 0,03520037 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02185759 0,03517682 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02185759 0,03515331 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02185759 0,03512983 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02185759 0,03510638 ! peptide cross-linking GO:0018149 37 19 0,000 0,02185759 0,03508296 ! protein export from nucleus GO:0006611 36 19 0,000 0,02185759 0,03505957 ! heart process GO:0003015 30 19 0,000 0,02185759 0,03503621 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02185759 0,03501288 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02185759 0,03498959 ! visual learning GO:0008542 36 19 0,000 0,02185759 0,03496632 ! cellular pigmentation GO:0033059 36 19 0,000 0,02185759 0,03494309 ! G1 phase GO:0051318 40 19 0,000 0,02185759 0,03491989 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02185759 0,03489672 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02185759 0,03487357 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02185759 0,03485046 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02185759 0,03482738 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02185759 0,03480434 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02185759 0,03478132 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02185759 0,03475833 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02185759 0,03473537 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02185759 0,03471244 ! cilium assembly GO:0042384 37 19 0,000 0,02185759 0,03468955 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02185759 0,03466668 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02299504 0,03644668 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02299504 0,03642268 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02299504 0,03639872 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02299504 0,03637479 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02299504 0,03635089 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02299504 0,03632702 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02299504 0,03630319 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02299504 0,03627938 ! response to vitamin GO:0033273 31 20 0,000 0,02299504 0,03625561 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02299504 0,03623186 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02299504 0,03620815 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02299504 0,03618447 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02299504 0,03616082 ! response to alkaloid GO:0043279 38 20 0,000 0,02299504 0,0361372 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02299504 0,03611361 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02299504 0,03609006 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02299504 0,03606653 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02299504 0,03604303 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02299504 0,03601957 ! cellular response to starvation GO:0009267 33 20 0,000 0,02299504 0,03599613 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02299504 0,03597273 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02299504 0,03594935 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02299504 0,03592601 ! body fluid secretion GO:0007589 31 20 0,000 0,02299504 0,0359027 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02299504 0,03587941 ! peptide secretion GO:0002790 35 20 0,000 0,02299504 0,03585616 ! stem cell differentiation GO:0048863 53 20 0,000 0,02299504 0,03583294 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02299504 0,03580975 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02299504 0,03578658 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02299504 0,03576345 ! sensory perception of pain GO:0019233 30 20 0,000 0,02299504 0,03574035 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02299504 0,03571727 ! diencephalon development GO:0021536 34 20 0,000 0,02299504 0,03569423 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02299504 0,03567122 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02299504 0,03564823 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02299504 0,03562528 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02299504 0,03560235 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02299504 0,03557946 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02299504 0,03555659 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02299504 0,03553376 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02299504 0,03551095 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02299504 0,03548817 ! regulation of glucose import GO:0046324 29 20 0,000 0,02299504 0,03546542 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02299504 0,0354427 ! actin filament-based movement GO:0030048 43 20 0,000 0,02299504 0,03542001 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02299504 0,03539735 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02299504 0,03537472 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02299504 0,03535211 ! negative regulation of translation GO:0017148 29 20 0,000 0,02299504 0,03532954 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02299504 0,03530699 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02299504 0,03528448 ! regulation of cell killing GO:0031341 42 21 0,000 0,0241312 0,03700425 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0241312 0,03698068 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0241312 0,03695714 ! hormone secretion GO:0046879 38 21 0,000 0,0241312 0,03693363 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0241312 0,03691015 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0241312 0,0368867 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0241312 0,03686328 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0241312 0,03683989 ! axis specification GO:0009798 38 21 0,000 0,0241312 0,03681653 ! ovarian follicle development GO:0001541 35 21 0,000 0,0241312 0,0367932 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0241312 0,0367699 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0241312 0,03674663 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0241312 0,03672338 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,0241312 0,03670017 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0241312 0,03667699 ! cell aging GO:0007569 44 21 0,000 0,0241312 0,03665383 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0241312 0,03663071 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0241312 0,03660761 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0241312 0,03658454 ! cytolysis GO:0019835 24 21 0,000 0,0241312 0,03656151 ! vasodilation GO:0042311 39 21 0,000 0,0241312 0,0365385 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0241312 0,03651552 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0241312 0,03649257 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0241312 0,03646964 ! oogenesis GO:0048477 36 21 0,000 0,0241312 0,03644675 ! DNA modification GO:0006304 34 21 0,000 0,0241312 0,03642388 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0241312 0,03640105 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0241312 0,03637824 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0241312 0,03635546 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0241312 0,03633271 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,0241312 0,03630999 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0241312 0,03628729 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0241312 0,03626463 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0241312 0,03624199 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0241312 0,03621938 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0241312 0,0361968 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0241312 0,03617425 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0241312 0,03615173 ! gut development GO:0048565 39 21 0,000 0,0241312 0,03612923 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02526608 0,03780485 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02526608 0,03778135 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02526608 0,03775789 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02526608 0,03773445 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02526608 0,03771104 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02526608 0,03768766 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02526608 0,03766431 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02526608 0,03764099 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02526608 0,0376177 ! regeneration GO:0031099 41 22 0,000 0,02526608 0,03759443 ! keratinization GO:0031424 28 22 0,000 0,02526608 0,0375712 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02526608 0,03754799 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02526608 0,03752481 ! sensory perception of taste GO:0050909 28 22 0,000 0,02526608 0,03750166 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02526608 0,03747854 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02526608 0,03745545 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02526608 0,03743239 ! vacuolar transport GO:0007034 36 22 0,000 0,02526608 0,03740935 ! lysosome organization GO:0007040 41 22 0,000 0,02526608 0,03738635 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02526608 0,03736337 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02526608 0,03734042 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02526608 0,03731749 ! fucose metabolic process GO:0006004 39 22 0,000 0,02526608 0,0372946 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02526608 0,03727173 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02526608 0,0372489 ! ureteric bud development GO:0001657 43 22 0,000 0,02526608 0,03722609 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02526608 0,0372033 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02526608 0,03718055 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02526608 0,03715782 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02526608 0,03713512 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02526608 0,03711245 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02526608 0,03708981 ! sarcomere organization GO:0045214 30 22 0,000 0,02526608 0,03706719 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02526608 0,03704461 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02526608 0,03702204 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02526608 0,03699951 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02526608 0,03697701 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02526608 0,03695453 ! protein stabilization GO:0050821 39 22 0,000 0,02526608 0,03693208 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02639968 0,03856566 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02639968 0,03854226 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02639968 0,03851888 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02639968 0,03849554 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02639968 0,03847222 ! gluconeogenesis GO:0006094 33 23 0,000 0,02639968 0,03844893 ! viral genome replication GO:0019079 41 23 0,000 0,02639968 0,03842567 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02639968 0,03840244 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02639968 0,03837924 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02639968 0,03835606 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02639968 0,03833291 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02639968 0,03830979 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02639968 0,0382867 ! visual behavior GO:0007632 42 23 0,000 0,02639968 0,03826364 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02639968 0,0382406 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02639968 0,03821759 ! response to ethanol GO:0045471 46 23 0,000 0,02639968 0,03819461 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02639968 0,03817166 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02639968 0,03814873 ! peroxisome organization GO:0007031 37 23 0,000 0,02639968 0,03812583 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02639968 0,03810296 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02639968 0,03808012 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02639968 0,0380573 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02639968 0,03803451 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02639968 0,03801175 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02639968 0,03798902 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02639968 0,03796631 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02639968 0,03794363 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02639968 0,03792098 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02639968 0,03789835 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02639968 0,03787575 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02639968 0,03785318 ! fatty acid transport GO:0015908 44 23 0,000 0,02639968 0,03783064 ! platelet activation GO:0030168 37 23 0,000 0,02639968 0,03780812 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02639968 0,03778563 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02639968 0,03776316 ! hormone transport GO:0009914 40 23 0,000 0,02639968 0,03774072 ! cell-cell recognition GO:0009988 25 23 0,000 0,02639968 0,03771831 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02639968 0,03769593 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02639968 0,03767357 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02639968 0,03765124 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02639968 0,03762893 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02639968 0,03760665 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,027532 0,03919645 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,027532 0,03917327 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,027532 0,03915012 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,027532 0,03912699 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,027532 0,03910389 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,027532 0,03908082 ! vesicle docking GO:0048278 47 24 0,000 0,027532 0,03905778 ! spinal cord development GO:0021510 47 24 0,000 0,027532 0,03903477 ! vacuole organization GO:0007033 43 24 0,000 0,027532 0,03901178 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,027532 0,03898882 ! digestive system process GO:0022600 39 24 0,000 0,027532 0,03896588 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,027532 0,03894297 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,027532 0,03892009 ! regulation of behavior GO:0050795 43 24 0,000 0,027532 0,03889724 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,027532 0,03887441 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,027532 0,03885161 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,027532 0,03882884 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,027532 0,03880609 ! membrane depolarization GO:0051899 39 24 0,000 0,027532 0,03878337 ! pallium development GO:0021543 49 24 0,000 0,027532 0,03876068 ! pentose metabolic process GO:0019321 35 24 0,000 0,027532 0,03873801 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,027532 0,03871537 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,027532 0,03869276 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,027532 0,03867017 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,027532 0,03864761 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,027532 0,03862507 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,027532 0,03860256 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,027532 0,03858008 ! regulation of amine transport GO:0051952 40 24 0,000 0,027532 0,03855762 ! protein tetramerization GO:0051262 52 24 0,000 0,027532 0,03853519 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02866304 0,04009493 ! myelination GO:0042552 45 25 0,000 0,02866304 0,04007163 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02866304 0,04004836 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02866304 0,04002512 ! phototransduction GO:0007602 33 25 0,000 0,02866304 0,0400019 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02866304 0,03997871 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02866304 0,03995555 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02866304 0,03993241 ! sperm motility GO:0030317 31 25 0,000 0,02866304 0,03990931 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02866304 0,03988622 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02866304 0,03986317 ! receptor metabolic process GO:0043112 46 25 0,000 0,02866304 0,03984014 ! chromosome condensation GO:0030261 45 25 0,000 0,02866304 0,03981714 ! response to starvation GO:0042594 42 25 0,000 0,02866304 0,03979416 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02866304 0,03977121 ! neural crest cell development GO:0014032 54 25 0,000 0,02866304 0,03974829 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02866304 0,03972539 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02866304 0,03970252 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02866304 0,03967968 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02866304 0,03965686 ! interaction with host GO:0051701 62 25 0,000 0,02866304 0,03963407 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02866304 0,0396113 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02866304 0,03958856 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02866304 0,03956585 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02866304 0,03954317 ! immunoglobulin production GO:0002377 55 25 0,000 0,02866304 0,0395205 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02866304 0,03949787 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02866304 0,03947526 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02866304 0,03945268 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02866304 0,03943012 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02866304 0,03940759 ! telomere organization GO:0032200 43 25 0,000 0,02866304 0,03938508 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02866304 0,0393626 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02866304 0,03934015 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0297928 0,04086744 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0297928 0,04084415 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0297928 0,04082089 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0297928 0,04079766 ! initiation of viral infection GO:0019059 57 26 0,000 0,0297928 0,04077445 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0297928 0,04075127 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0297928 0,04072812 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0297928 0,04070499 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0297928 0,04068189 ! molting cycle process GO:0022404 50 26 0,000 0,0297928 0,04065881 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0297928 0,04063576 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0297928 0,04061274 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,0297928 0,04058974 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0297928 0,04056677 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0297928 0,04054383 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,0297928 0,04052091 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0297928 0,04049802 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0297928 0,04047515 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0297928 0,04045231 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0297928 0,04042949 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0297928 0,0404067 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0297928 0,04038394 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0297928 0,0403612 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0297928 0,04033848 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0297928 0,0403158 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0297928 0,04029313 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0297928 0,0402705 ! blastocyst development GO:0001824 49 26 0,000 0,0297928 0,04024789 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0297928 0,0402253 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0297928 0,04020274 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0297928 0,04018021 ! neuron fate commitment GO:0048663 48 27 0,000 0,03092129 0,04167878 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03092129 0,04165544 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03092129 0,04163213 ! iron ion transport GO:0006826 59 27 0,000 0,03092129 0,04160885 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03092129 0,04158559 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03092129 0,04156236 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03092129 0,04153915 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03092129 0,04151597 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03092129 0,04149282 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03092129 0,04146969 ! autophagy GO:0006914 41 27 0,000 0,03092129 0,04144659 ! male gonad development GO:0008584 44 27 0,000 0,03092129 0,04142351 ! response to toxin GO:0009636 47 27 0,000 0,03092129 0,04140046 ! primary neural tube formation GO:0014020 51 27 0,000 0,03092129 0,04137743 ! base-excision repair GO:0006284 41 27 0,000 0,03092129 0,04135443 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03092129 0,04133146 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03092129 0,04130851 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03092129 0,04128558 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03092129 0,04126269 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03092129 0,04123981 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03092129 0,04121697 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03092129 0,04119414 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03092129 0,04117135 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0320485 0,04264861 ! circadian rhythm GO:0007623 50 28 0,000 0,0320485 0,04262504 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0320485 0,04260149 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0320485 0,04257796 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0320485 0,04255446 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0320485 0,04253099 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0320485 0,04250755 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0320485 0,04248413 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0320485 0,04246073 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0320485 0,04243736 ! synaptogenesis GO:0007416 42 28 0,000 0,0320485 0,04241402 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,0320485 0,0423907 ! lipid oxidation GO:0034440 43 28 0,000 0,0320485 0,04236741 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0320485 0,04234415 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0320485 0,04232091 ! translational initiation GO:0006413 65 29 0,000 0,03317444 0,0437837 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03317444 0,0437597 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03317444 0,04373572 ! regulation of pH GO:0006885 43 29 0,000 0,03317444 0,04371177 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03317444 0,04368785 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03317444 0,04366395 ! catechol metabolic process GO:0009712 54 29 0,000 0,03317444 0,04364007 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03317444 0,04361623 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03317444 0,0435924 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03317444 0,04356861 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03317444 0,04354484 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03317444 0,0435211 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03317444 0,04349738 ! cell fate determination GO:0001709 60 29 0,000 0,03317444 0,04347369 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03317444 0,04345002 ! detection of light stimulus GO:0009583 38 29 0,000 0,03317444 0,04342638 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03317444 0,04340277 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03317444 0,04337918 ! tissue homeostasis GO:0001894 48 29 0,000 0,03317444 0,04335562 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03317444 0,04333208 ! phenol metabolic process GO:0018958 55 30 0,000 0,0342991 0,0447768 ! zinc ion transport GO:0006829 45 30 0,000 0,0342991 0,04475251 ! membrane docking GO:0022406 61 30 0,000 0,0342991 0,04472826 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0342991 0,04470403 ! cell junction assembly GO:0034329 78 30 0,000 0,0342991 0,04467982 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0342991 0,04465565 ! acute-phase response GO:0006953 49 30 0,000 0,0342991 0,0446315 ! myofibril assembly GO:0030239 47 30 0,000 0,0342991 0,04460737 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0342991 0,04458327 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0342991 0,0445592 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0342991 0,04453515 ! phospholipid transport GO:0015914 51 30 0,000 0,0342991 0,04451113 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0342991 0,04448713 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0342991 0,04446317 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0342991 0,04443922 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0342991 0,0444153 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0342991 0,04439141 ! eye morphogenesis GO:0048592 60 30 0,000 0,0342991 0,04436755 ! response to heat GO:0009408 50 30 0,000 0,0342991 0,04434371 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03542249 0,04577149 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03542249 0,04574692 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03542249 0,04572238 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03542249 0,04569787 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03542249 0,04567338 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03542249 0,04564891 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03542249 0,04562448 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03542249 0,04560006 ! ovulation cycle process GO:0022602 49 31 0,000 0,03542249 0,04557568 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03542249 0,04555132 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03542249 0,04552699 ! peptide transport GO:0015833 55 31 0,000 0,03542249 0,04550268 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03542249 0,0454784 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03542249 0,04545414 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03542249 0,04542991 ! mesoderm formation GO:0001707 69 31 0,000 0,03542249 0,04540571 ! natural killer cell activation GO:0030101 45 31 0,000 0,03542249 0,04538153 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03542249 0,04535738 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03542249 0,04533325 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03542249 0,04530915 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03542249 0,04528508 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03542249 0,04526103 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03654462 0,04667004 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03654462 0,04664528 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03654462 0,04662055 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03654462 0,04659584 ! cholesterol transport GO:0030301 56 32 0,000 0,03654462 0,04657116 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03654462 0,04654651 ! spindle organization GO:0007051 46 32 0,000 0,03654462 0,04652188 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03654462 0,04649728 ! metanephros development GO:0001656 74 32 0,000 0,03654462 0,0464727 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03654462 0,04644815 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03654462 0,04642363 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03654462 0,04639913 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03654462 0,04637466 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03654462 0,04635021 ! muscle cell development GO:0055001 49 32 0,000 0,03654462 0,04632579 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03654462 0,04630139 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03654462 0,04627703 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03654462 0,04625268 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03654462 0,04622836 ! ovulation cycle GO:0042698 51 32 0,000 0,03654462 0,04620407 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03654462 0,04617981 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03654462 0,04615556 ! hindbrain development GO:0030902 61 32 0,000 0,03654462 0,04613135 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03654462 0,04610716 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03654462 0,04608299 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03654462 0,04605885 ! gene silencing GO:0016458 65 32 0,000 0,03654462 0,04603474 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03766547 0,04742184 ! post-embryonic development GO:0009791 69 33 0,000 0,03766547 0,04739703 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03766547 0,04737226 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03766547 0,04734751 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03766547 0,04732278 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03766547 0,04729808 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03766547 0,04727341 ! cell fate specification GO:0001708 52 33 0,000 0,03766547 0,04724876 ! sterol transport GO:0015918 57 33 0,000 0,03766547 0,04722414 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03766547 0,04719955 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03766547 0,04717498 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03766547 0,04715043 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03766547 0,04712591 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03766547 0,04710142 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03878506 0,04847629 ! glial cell differentiation GO:0010001 63 34 0,000 0,03878506 0,04845112 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03878506 0,04842598 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03878506 0,04840086 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03878506 0,04837577 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03878506 0,0483507 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03878506 0,04832566 ! mismatch repair GO:0006298 46 34 0,000 0,03878506 0,04830065 ! spermatid development GO:0007286 63 34 0,000 0,03878506 0,04827566 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03878506 0,0482507 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03878506 0,04822577 ! placenta development GO:0001890 53 34 0,000 0,03878506 0,04820086 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03878506 0,04817597 ! regulation of muscle development GO:0048634 70 35 0,000 0,03990338 0,0495395 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03990338 0,04951395 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03990338 0,04948842 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03990338 0,04946293 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03990338 0,04943746 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03990338 0,04941201 ! odontogenesis GO:0042476 66 35 0,000 0,03990338 0,0493866 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03990338 0,04936121 ! female gonad development GO:0008585 58 35 0,000 0,03990338 0,04933584 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03990338 0,0493105 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03990338 0,04928519 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,03990338 0,0492599 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03990338 0,04923464 ! cytokine production GO:0001816 59 35 0,000 0,03990338 0,0492094 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,03990338 0,04918419 ! neural tube formation GO:0001841 67 35 0,000 0,03990338 0,04915901 ! vesicle localization GO:0051648 64 35 0,000 0,03990338 0,04913385 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04102044 0,05048347 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,04102044 0,05045766 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04102044 0,05043188 ! cell junction organization GO:0034330 86 36 0,000 0,04102044 0,05040612 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,04102044 0,05038039 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04102044 0,05035469 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04102044 0,05032901 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04102044 0,05030336 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04102044 0,05027773 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,04102044 0,05025213 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04102044 0,05022656 ! aerobic respiration GO:0009060 55 36 0,000 0,04102044 0,05020101 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,04102044 0,05017549 ! embryonic organ development GO:0048568 57 36 0,000 0,04102044 0,05014999 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,04102044 0,05012452 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04102044 0,05009908 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04213624 0,05143572 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04213624 0,05140963 ! meiosis I GO:0007127 65 37 0,000 0,04213624 0,05138358 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,04213624 0,05135755 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04213624 0,05133154 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04213624 0,05130556 ! organic anion transport GO:0015711 68 37 0,000 0,04213624 0,05127961 ! tissue remodeling GO:0048771 76 37 0,000 0,04213624 0,05125369 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04213624 0,05122779 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04213624 0,05120192 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04213624 0,05117607 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04213624 0,05115025 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04213624 0,05112446 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04213624 0,05109869 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04213624 0,05107295 ! pigment metabolic process GO:0042440 80 37 0,000 0,04213624 0,05104723 ! spermatid differentiation GO:0048515 66 37 0,000 0,04213624 0,05102154 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04213624 0,05099587 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04325078 0,05231844 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04325078 0,05229215 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04325078 0,05226588 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04325078 0,05223964 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04325078 0,05221343 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04325078 0,05218725 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04325078 0,05216109 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04325078 0,05213495 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04325078 0,05210885 ! lipid homeostasis GO:0055088 67 38 0,000 0,04325078 0,05208277 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04325078 0,05205671 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04325078 0,05203068 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04325078 0,05200468 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04325078 0,05197871 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04325078 0,05195276 ! glucan metabolic process GO:0044042 62 38 0,000 0,04325078 0,05192683 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,04436405 0,05323686 ! mammary gland development GO:0030879 86 39 0,000 0,04436405 0,05321032 ! learning GO:0007612 77 39 0,000 0,04436405 0,05318381 ! ear morphogenesis GO:0042471 60 39 0,000 0,04436405 0,05315733 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04436405 0,05313087 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04436405 0,05310443 ! segmentation GO:0035282 67 39 0,000 0,04436405 0,05307803 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04436405 0,05305165 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04436405 0,05302529 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04436405 0,05299896 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04436405 0,05297266 ! RNA modification GO:0009451 57 39 0,000 0,04436405 0,05294638 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04436405 0,05292013 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04547607 0,05421973 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04547607 0,05419288 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04547607 0,05416605 ! feeding behavior GO:0007631 59 40 0,000 0,04547607 0,05413925 ! negative regulation of binding GO:0051100 72 40 0,000 0,04547607 0,05411247 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04547607 0,05408573 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04547607 0,054059 ! maintenance of protein location GO:0045185 91 40 0,000 0,04547607 0,05403231 ! cytokinesis GO:0000910 72 40 0,000 0,04547607 0,05400564 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04658683 0,05529744 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04658683 0,05527017 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04658683 0,05524293 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04658683 0,05521572 ! gliogenesis GO:0042063 88 41 0,000 0,04658683 0,05518853 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04658683 0,05516137 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04658683 0,05513424 ! T cell differentiation GO:0030217 81 41 0,000 0,04658683 0,05510714 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,04658683 0,05508006 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04658683 0,055053 ! female gamete generation GO:0007292 61 41 0,000 0,04658683 0,05502598 ! polyol metabolic process GO:0019751 66 41 0,000 0,04658683 0,05499898 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04658683 0,054972 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,04769633 0,05625362 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,04769633 0,05622606 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,04769633 0,05619852 ! regulation of tube size GO:0035150 71 42 0,000 0,04769633 0,05617101 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,04769633 0,05614353 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,04769633 0,05611608 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,04769633 0,05608865 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,04769633 0,05606125 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,04769633 0,05603388 ! neuron migration GO:0001764 79 42 0,000 0,04769633 0,05600653 ! regulation of protein secretion GO:0050708 71 42 0,000 0,04769633 0,05597921 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,04769633 0,05595192 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,04880459 0,05722409 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04880459 0,05719622 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04880459 0,05716837 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04880459 0,05714055 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04880459 0,05711276 ! glucose transport GO:0015758 65 43 0,000 0,04880459 0,05708499 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,04880459 0,05705726 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04880459 0,05702954 ! neural tube development GO:0021915 77 43 0,000 0,04880459 0,05700186 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04880459 0,0569742 ! striated muscle contraction GO:0006941 77 43 0,000 0,04880459 0,05694657 ! phagocytosis GO:0006909 90 43 0,000 0,04880459 0,05691897 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04880459 0,05689139 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04991158 0,05815364 ! hexose transport GO:0008645 67 44 0,000 0,04991158 0,05812549 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04991158 0,05809737 ! male sex differentiation GO:0046661 76 44 0,000 0,04991158 0,05806928 ! double-strand break repair GO:0006302 81 44 0,000 0,04991158 0,05804121 ! biopolymer methylation GO:0043414 84 44 0,000 0,04991158 0,05801317 ! B cell differentiation GO:0030183 107 44 0,000 0,04991158 0,05798516 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04991158 0,05795718 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04991158 0,05792922 ! developmental growth GO:0048589 82 44 0,000 0,04991158 0,05790129 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04991158 0,05787338 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05101733 0,05912702 ! glycolysis GO:0006096 65 45 0,000 0,05101733 0,05909855 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,05101733 0,05907011 ! leukocyte migration GO:0050900 68 45 0,000 0,05101733 0,0590417 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05101733 0,05901331 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05101733 0,05898496 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05101733 0,05895662 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05101733 0,05892832 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05101733 0,05890004 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05101733 0,05887179 ! cell growth GO:0016049 84 45 0,000 0,05101733 0,05884357 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05212182 0,0600887 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05212182 0,06005992 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05212182 0,06003117 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05212182 0,06000244 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,05212182 0,05997375 ! pigmentation GO:0043473 100 46 0,000 0,05212182 0,05994508 ! response to insulin stimulus GO:0032868 95 46 0,000 0,05212182 0,05991644 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05212182 0,05988783 ! positive regulation of defense response GO:0031349 76 47 0,000 0,05322507 0,06112626 ! endosome transport GO:0016197 108 47 0,000 0,05322507 0,0610971 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,05322507 0,06106796 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,05322507 0,06103886 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,05322507 0,06100978 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,05322507 0,06098072 ! JNK cascade GO:0007254 91 47 0,000 0,05322507 0,0609517 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,05322507 0,0609227 ! methylation GO:0032259 90 47 0,000 0,05322507 0,06089373 ! protein homooligomerization GO:0051260 76 47 0,000 0,05322507 0,06086479 ! mitochondrial transport GO:0006839 82 48 0,000 0,05432707 0,06209545 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05432707 0,06206597 ! cellular component disassembly GO:0022411 86 48 0,000 0,05432707 0,06203651 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05432707 0,06200708 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,05432707 0,06197768 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,05432707 0,06194831 ! activation of caspase activity GO:0006919 84 48 0,000 0,05432707 0,06191896 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05432707 0,06188965 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05432707 0,06186036 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05432707 0,06183109 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,05542782 0,06305406 ! regulation of action potential GO:0001508 95 49 0,000 0,05542782 0,06302426 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,05542782 0,06299449 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,05542782 0,06296475 ! regulation of ion transport GO:0043269 77 49 0,000 0,05542782 0,06293504 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,05542782 0,06290535 ! peptide metabolic process GO:0006518 76 49 0,000 0,05542782 0,06287569 ! response to temperature stimulus GO:0009266 76 49 0,000 0,05542782 0,06284606 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,05542782 0,06281646 ! endocrine system development GO:0035270 104 49 0,000 0,05542782 0,06278688 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,05542782 0,06275734 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,05542782 0,06272782 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,05652733 0,06394206 ! neuromuscular process GO:0050905 99 50 0,000 0,05652733 0,06391201 ! regulation of ossification GO:0030278 117 50 0,000 0,05652733 0,06388199 ! inner ear development GO:0048839 79 50 0,000 0,05652733 0,063852 ! histone modification GO:0016570 91 50 0,000 0,05652733 0,06382204 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05652733 0,0637921 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05652733 0,06376219 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05652733 0,06373232 ! positive regulation of binding GO:0051099 78 51 0,000 0,0576256 0,06494013 ! viral infectious cycle GO:0019058 99 51 0,000 0,0576256 0,06490973 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,0576256 0,06487936 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,0576256 0,06484901 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,0576256 0,06481869 ! excretion GO:0007588 83 51 0,000 0,0576256 0,06478841 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,0576256 0,06475814 ! chromatin remodeling GO:0006338 109 51 0,000 0,0576256 0,06472791 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,0576256 0,06469771 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,0576256 0,06466753 ! vesicle organization GO:0016050 107 51 0,000 0,0576256 0,06463738 ! regulation of cell shape GO:0008360 125 51 0,000 0,0576256 0,06460726 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,0576256 0,06457717 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,05872262 0,0657759 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,05872262 0,06574529 ! membrane fusion GO:0006944 110 52 0,000 0,05872262 0,06571471 ! positive regulation of growth GO:0045927 90 52 0,000 0,05872262 0,06568416 ! covalent chromatin modification GO:0016569 101 52 0,000 0,05872262 0,06565364 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,05872262 0,06562314 ! amino acid activation GO:0043038 92 52 0,000 0,05872262 0,06559268 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,05872262 0,06556224 ! synapse organization GO:0050808 85 52 0,000 0,05872262 0,06553183 ! RNA catabolic process GO:0006401 93 53 0,000 0,0598184 0,06672373 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0598184 0,06669281 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0598184 0,06666192 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0598184 0,06663106 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0598184 0,06660022 ! cell maturation GO:0048469 100 53 0,000 0,0598184 0,06656942 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0598184 0,06653864 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0598184 0,06650789 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06091295 0,06769356 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06091295 0,0676623 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06091295 0,06763108 ! cell recognition GO:0008037 85 54 0,000 0,06091295 0,06759989 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06091295 0,06756872 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06091295 0,06753758 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06091295 0,06750647 ! chloride transport GO:0006821 90 55 0,000 0,06200625 0,06868648 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,06200625 0,06865488 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,06200625 0,0686233 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,06200625 0,06859174 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,06200625 0,06856022 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,06200625 0,06852873 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,06200625 0,06849727 ! aging GO:0007568 103 55 0,000 0,06200625 0,06846583 ! gastrulation GO:0007369 112 55 0,000 0,06200625 0,06843442 ! heart morphogenesis GO:0003007 97 55 0,000 0,06200625 0,06840305 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,06200625 0,0683717 ! RNA elongation GO:0006354 79 55 0,000 0,06200625 0,06834038 ! nuclear export GO:0051168 97 55 0,000 0,06200625 0,06830909 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,06200625 0,06827782 ! regulation of actin filament length GO:0030832 105 56 0,000 0,06309832 0,06944856 ! sensory perception of smell GO:0007608 80 56 0,000 0,06309832 0,06941681 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,06309832 0,06938508 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,06309832 0,06935339 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,06309832 0,06932172 ! regulation of DNA replication GO:0006275 101 56 0,000 0,06309832 0,06929008 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,06309832 0,06925847 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06418916 0,07042367 ! muscle fiber development GO:0048747 112 57 0,000 0,06418916 0,07039157 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06418916 0,0703595 ! lipid modification GO:0030258 97 57 0,000 0,06418916 0,07032746 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06418916 0,07029545 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,06418916 0,07026347 ! maintenance of location GO:0051235 118 57 0,000 0,06418916 0,07023152 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,06527876 0,07139122 ! regulation of endocytosis GO:0030100 91 58 0,000 0,06527876 0,07135879 ! adult behavior GO:0030534 99 58 0,000 0,06527876 0,07132638 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,06527876 0,071294 ! positive regulation of secretion GO:0051047 95 59 0,000 0,06636712 0,07244977 ! regulation of cellular component size GO:0032535 109 59 0,000 0,06636712 0,07241692 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,06636712 0,07238409 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,06636712 0,07235129 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,06636712 0,07231852 ! DNA catabolic process GO:0006308 86 59 0,000 0,06636712 0,07228579 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,06636712 0,07225308 ! establishment of organelle localization GO:0051656 109 59 0,000 0,06636712 0,0722204 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,06745426 0,07337023 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,06745426 0,07333708 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,06745426 0,07330395 ! regulation of heart contraction GO:0008016 110 60 0,000 0,06745426 0,07327086 ! camera-type eye development GO:0043010 116 60 0,000 0,06745426 0,07323779 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,06745426 0,07320476 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,06745426 0,07317175 ! kidney development GO:0001822 122 60 0,000 0,06745426 0,07313878 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,06854017 0,07428272 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,06854017 0,07424928 ! mesoderm development GO:0007498 119 61 0,000 0,06854017 0,07421586 ! tRNA processing GO:0008033 89 61 0,000 0,06854017 0,07418247 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,06854017 0,07414912 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,06854017 0,07411579 ! ear development GO:0043583 103 62 0,000 0,06962485 0,07525489 ! viral reproductive process GO:0022415 126 62 0,000 0,06962485 0,07522109 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,06962485 0,07518733 ! gonad development GO:0008406 98 62 0,000 0,06962485 0,0751536 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,06962485 0,0751199 ! regulation of mitosis GO:0007088 105 63 0,000 0,0707083 0,07625467 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,0707083 0,0762205 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,0707083 0,07618637 ! detection of external stimulus GO:0009581 91 63 0,000 0,0707083 0,07615227 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,0707083 0,07611819 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,0707083 0,07608415 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,07179052 0,07721412 ! cell redox homeostasis GO:0045454 102 64 0,000 0,07179052 0,07717962 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,07179052 0,07714515 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,07179052 0,07711071 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,07179052 0,0770763 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,07179052 0,07704193 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,07287152 0,07816714 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,07287152 0,0781323 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,07287152 0,0780975 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,07287152 0,07806273 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,07287152 0,07802799 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,0739513 0,07914895 ! actin filament organization GO:0007015 148 66 0,000 0,0739513 0,07911375 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,0739513 0,07907859 ! extracellular matrix organization GO:0030198 133 66 0,000 0,0739513 0,07904346 ! secondary metabolic process GO:0019748 116 66 0,000 0,0739513 0,07900836 ! developmental maturation GO:0021700 116 66 0,000 0,0739513 0,07897329 ! cell projection assembly GO:0030031 120 66 0,000 0,0739513 0,07893826 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,07502986 0,08005403 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,07502986 0,08001855 ! activation of MAPK activity GO:0000187 115 67 0,000 0,07502986 0,07998309 ! lung development GO:0030324 144 67 0,000 0,07502986 0,07994767 ! chromosome segregation GO:0007059 113 67 0,000 0,07502986 0,07991228 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,07502986 0,07987692 ! hexose catabolic process GO:0019320 104 67 0,000 0,07502986 0,07984159 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,07502986 0,0798063 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,07502986 0,07977103 ! adaptive immune response GO:0002250 119 67 0,000 0,07502986 0,07973579 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,07502986 0,07970059 ! amino acid transport GO:0006865 125 68 0,000 0,07610719 0,08080932 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,07610719 0,08077367 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,07610719 0,08073806 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,07610719 0,08070247 ! viral reproduction GO:0016032 134 68 0,000 0,07610719 0,08066692 ! regulation of lipase activity GO:0060191 130 68 0,000 0,07610719 0,0806314 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,07610719 0,08059591 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,07718331 0,08169954 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,07718331 0,08166361 ! urogenital system development GO:0001655 137 69 0,000 0,07718331 0,08162771 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,07718331 0,08159185 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,07718331 0,08155602 ! antigen processing and presentation GO:0019882 104 69 0,000 0,07718331 0,08152021 ! appendage morphogenesis GO:0035107 135 70 0,000 0,07825821 0,08261924 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,07825821 0,08258301 ! amine catabolic process GO:0009310 117 71 0,000 0,0793319 0,08367932 ! reproductive structure development GO:0048608 113 71 0,000 0,0793319 0,08364266 ! appendage development GO:0048736 136 71 0,000 0,0793319 0,08360602 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0793319 0,08356941 ! B cell activation GO:0042113 160 71 0,000 0,0793319 0,08353284 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0793319 0,0834963 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0793319 0,08345979 ! acute inflammatory response GO:0002526 113 72 0,000 0,08040436 0,08455109 ! regulation of caspase activity GO:0043281 122 72 0,000 0,08040436 0,08451415 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,08040436 0,08447725 ! carbohydrate transport GO:0008643 110 72 0,000 0,08040436 0,08444037 ! respiratory system development GO:0060541 153 72 0,000 0,08040436 0,08440353 ! learning or memory GO:0007611 147 73 0,000 0,08147562 0,08549077 ! regulation of blood pressure GO:0008217 125 73 0,000 0,08147562 0,0854535 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,08147562 0,08541627 ! axon guidance GO:0007411 139 73 0,000 0,08147562 0,08537907 ! fertilization GO:0009566 90 73 0,000 0,08147562 0,0853419 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,08254566 0,08642509 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,08254566 0,0863875 ! neurotransmitter transport GO:0006836 123 74 0,000 0,08254566 0,08634994 ! meiosis GO:0007126 121 74 0,000 0,08254566 0,08631241 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,08254566 0,08627492 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,08254566 0,08623746 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,08254566 0,08620003 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,08254566 0,08616263 ! eye development GO:0001654 143 74 0,000 0,08254566 0,08612526 ! organelle localization GO:0051640 136 74 0,000 0,08254566 0,08608793 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,08361449 0,08716485 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,08361449 0,0871271 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,08361449 0,08708938 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,08361449 0,0870517 ! meiotic cell cycle GO:0051321 122 75 0,000 0,08361449 0,08701404 ! rhythmic process GO:0048511 128 75 0,000 0,08361449 0,08697642 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,08361449 0,08693884 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,08468211 0,08801087 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,08468211 0,08797287 ! defense response to bacterium GO:0042742 89 76 0,000 0,08468211 0,0879349 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,08468211 0,08789697 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,08468211 0,08785906 ! regulation of catabolic process GO:0009894 161 76 0,000 0,08468211 0,08782119 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,08574853 0,08888882 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,08574853 0,08885054 ! blood coagulation GO:0007596 146 78 0,000 0,08681373 0,08991556 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,08681373 0,08987687 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,08681373 0,08983821 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,08681373 0,08979959 ! protein oligomerization GO:0051259 139 78 0,000 0,08681373 0,089761 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,08787773 0,09082209 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,08787773 0,0907831 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,08787773 0,09074413 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,08787773 0,0907052 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,08787773 0,09066631 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,08894053 0,0917235 ! muscle cell differentiation GO:0042692 159 80 0,000 0,08894053 0,0916842 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,08894053 0,09164493 ! protein import into nucleus GO:0006606 158 80 0,000 0,08894053 0,0916057 ! inorganic anion transport GO:0015698 138 80 0,000 0,08894053 0,0915665 ! T cell activation GO:0042110 168 81 0,000 0,09000212 0,09261981 ! response to hypoxia GO:0001666 171 81 0,000 0,09000212 0,09258021 ! digestion GO:0007586 112 81 0,000 0,09000212 0,09254065 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,09000212 0,09250112 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,09000212 0,09246162 ! nuclear import GO:0051170 161 81 0,000 0,09000212 0,09242216 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,09000212 0,09238273 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,09106252 0,09343131 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,09106252 0,09339148 ! response to drug GO:0042493 143 82 0,000 0,09106252 0,09335169 ! response to nutrient GO:0007584 125 82 0,000 0,09106252 0,09331193 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,09106252 0,09327221 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,09106252 0,09323252 ! response to oxygen levels GO:0070482 176 83 0,000 0,09212171 0,09427683 ! regulation of lyase activity GO:0051339 160 83 0,000 0,09212171 0,09423675 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,0931797 0,09527852 ! hemostasis GO:0007599 158 84 0,000 0,0931797 0,09523804 ! negative regulation of transport GO:0051051 153 84 0,000 0,0931797 0,0951976 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,0931797 0,0951572 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,09423649 0,09619559 ! amine biosynthetic process GO:0009309 138 86 0,000 0,09529209 0,09723188 ! tube morphogenesis GO:0035239 176 86 0,000 0,09529209 0,09719066 ! mitochondrion organization GO:0007005 148 86 0,000 0,09529209 0,09714948 ! alcohol catabolic process GO:0046164 130 86 0,000 0,09529209 0,09710833 ! amine transport GO:0015837 155 86 0,000 0,09529209 0,09706722 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,0963465 0,09809973 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,0963465 0,09805823 ! protein localization in nucleus GO:0034504 176 87 0,000 0,0963465 0,09801677 ! regulation of protein transport GO:0051223 154 87 0,000 0,0963465 0,09797535 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 0,000 0,0973997 0,09900452 ! gland development GO:0048732 206 88 0,000 0,0973997 0,09896271 ! regulation of neurological system process GO:0031644 148 88 0,000 0,0973997 0,09892093 ! cellular defense response GO:0006968 114 89 0,000 0,09845172 0,09994719 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,09845172 0,09990504 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,09845172 0,09986292 ! ossification GO:0001503 188 90 0,000 0,09950255 0,10088627 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,09950255 0,10084378 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,09950255 0,10080132 ! sex differentiation GO:0007548 145 90 0,000 0,09950255 0,10075889 ! bone development GO:0060348 189 91 0,000 0,10055218 0,10177894 ! sterol metabolic process GO:0016125 152 91 0,000 0,10055218 0,10173614 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,10055218 0,10169338 ! regulation of defense response GO:0031347 149 92 0,000 0,10160063 0,10271055 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,10160063 0,10266741 ! vitamin metabolic process GO:0006766 139 92 0,000 0,10160063 0,10262431 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,10264789 0,10363862 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,10264789 0,10359514 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,10264789 0,10355171 ! regulation of membrane potential GO:0042391 164 93 0,000 0,10264789 0,10350831 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,10264789 0,10346494 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,10369396 0,10447558 ! female pregnancy GO:0007565 164 94 0,000 0,10369396 0,10443184 ! transcription initiation GO:0006352 153 94 0,000 0,10369396 0,10438815 ! regulation of T cell activation GO:0050863 158 94 0,000 0,10369396 0,10434449 ! forebrain development GO:0030900 188 95 0,000 0,10473885 0,10535187 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,10473885 0,10530785 ! leukocyte differentiation GO:0002521 202 96 0,000 0,10578256 0,1063128 ! mRNA transport GO:0051028 169 96 0,000 0,10578256 0,10626841 ! positive regulation of immune response GO:0050778 156 96 0,000 0,10578256 0,10622406 ! detection of stimulus GO:0051606 151 96 0,000 0,10578256 0,10617974 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,10682508 0,10718146 ! protein ubiquitination GO:0016567 217 97 0,000 0,10682508 0,10713679 ! hormone metabolic process GO:0042445 157 97 0,000 0,10682508 0,10709215 ! regulation of protein localization GO:0032880 176 97 0,000 0,10682508 0,10704754 ! response to virus GO:0009615 160 98 0,000 0,10786643 0,10804605 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,10786643 0,10800109 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,10890659 0,10899719 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,10890659 0,10895187 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,10890659 0,10890659 GO:0060538|skeletal muscle organ development,