pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/9551-11-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! mRNA cleavage GO:0006379 18 10 2,000 1,24E-07 3,029E-04 ! mRNA polyadenylation GO:0006378 24 12 2,000 2,269E-07 2,772E-04 ! mRNA 3'-end processing GO:0031124 25 13 2,000 2,948E-07 2,401E-04 ! RNA polyadenylation GO:0043631 32 14 2,000 3,75E-07 2,29E-04 ! RNA 3'-end processing GO:0031123 37 17 2,000 6,99E-07 3,415E-04 ! collagen catabolic process GO:0030574 29 21 2,000 1,363E-06 5,55E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 2,351E-06 8,204E-04 ! multicellular organismal catabolic process GO:0044243 38 27 2,000 2,985E-06 9,116E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 3,346E-06 9,082E-04 ! collagen metabolic process GO:0032963 49 32 2,000 5,044E-06 1,232E-03 ! spliceosome assembly GO:0000245 75 34 2,000 6,076E-06 1,35E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 2,000 6,641E-06 1,352E-03 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 1,052E-05 1,977E-03 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 1,077E-05 1,879E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,528E-05 2,489E-03 ! ribonucleoprotein complex assembly GO:0022618 104 52 2,000 2,215E-05 3,383E-03 ! response to UV GO:0009411 120 55 2,000 2,624E-05 3,771E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 2,923E-05 3,967E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,941E-05 3,781E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 4,72E-05 5,765E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 4,72E-05 5,491E-03 ! thymus development GO:0048538 29 11 1,000 5,765E-05 6,401E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 6,913E-05 7,343E-03 ! T cell homeostasis GO:0043029 28 12 1,000 6,913E-05 7,037E-03 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,098E-04 0,01072631 ! DNA replication initiation GO:0006270 28 16 1,000 1,254E-04 0,01177942 ! mRNA splice site selection GO:0006376 44 16 1,000 1,254E-04 0,01134314 ! DNA unwinding during replication GO:0006268 26 17 1,000 1,42E-04 0,01238831 ! DNA duplex unwinding GO:0032508 30 20 1,000 1,98E-04 0,01667753 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,98E-04 0,01612162 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of B cell activation GO:0050871 42 22 1,000 2,404E-04 0,01894335 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,868E-04 0,02189757 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 3,116E-04 0,02306531 ! leukocyte homeostasis GO:0001776 50 25 1,000 3,116E-04 0,02238692 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 3,373E-04 0,02354412 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 3,373E-04 0,02289012 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,918E-04 0,02586948 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 3,918E-04 0,0251887 ! fat cell differentiation GO:0045444 57 28 1,000 3,918E-04 0,02454284 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 4,205E-04 0,02568496 ! regulation of B cell activation GO:0050864 55 30 1,000 4,503E-04 0,02683079 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 4,81E-04 0,02797996 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 1,000 6,496E-04 0,03690559 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 7,625E-04 0,04233814 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,015E-03 0,05509115 ! ATP synthesis coupled electron transport GO:0042773 69 45 1,000 1,015E-03 0,05389352 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,154E-03 0,05998147 ! response to calcium ion GO:0051592 94 49 1,000 1,202E-03 0,061191 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,202E-03 0,0599422 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 1,353E-03 0,06610615 ! respiratory electron transport chain GO:0022904 83 53 1,000 1,405E-03 0,06730744 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,405E-03 0,06601306 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! proton transport GO:0015992 117 61 1,000 1,856E-03 0,08556284 ! hydrogen transport GO:0006818 121 64 1,000 2,041E-03 0,09233244 ! negative regulation of cell growth GO:0030308 142 67 1,000 2,234E-03 0,09922732 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 2,3E-03 0,10034295 ! negative regulation of cell size GO:0045792 144 69 1,000 2,367E-03 0,10145893 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 2,367E-03 0,09970963 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 2,367E-03 0,09801964 ! homeostasis of number of cells GO:0048872 131 69 1,000 2,367E-03 0,09638598 ! negative regulation of kinase activity GO:0033673 145 70 1,000 2,435E-03 0,09753048 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 2,574E-03 0,10142715 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 2,574E-03 0,0998172 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 2,717E-03 0,10369594 ! negative regulation of transferase activity GO:0051348 155 74 1,000 2,717E-03 0,10210062 ! positive regulation of ligase activity GO:0051351 130 77 1,000 2,937E-03 0,10871657 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 3,012E-03 0,10984037 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 3,089E-03 0,11096356 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 3,244E-03 0,11484864 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 3,403E-03 0,11874797 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 3,483E-03 0,11985263 ! regulation of ligase activity GO:0051340 147 84 1,000 3,483E-03 0,11818801 ! negative regulation of growth GO:0045926 168 85 1,000 3,565E-03 0,11929991 ! positive regulation of cell activation GO:0050867 161 86 1,000 3,647E-03 0,12041114 GO:0002696|positive regulation of leukocyte activation, ! nucleosome assembly GO:0006334 126 87 1,000 3,731E-03 0,12152167 ! cellular respiration GO:0045333 143 88 1,000 3,815E-03 0,12263146 ! chromatin assembly GO:0031497 128 88 1,000 3,815E-03 0,12103885 ! response to inorganic substance GO:0010035 173 90 1,000 3,986E-03 0,12484873 ! oxidative phosphorylation GO:0006119 152 90 1,000 3,986E-03 0,12326837 ! positive regulation of protein modification process GO:0031401 156 90 1,000 3,986E-03 0,12172751 ! response to unfolded protein GO:0006986 139 90 1,000 3,986E-03 0,1202247 ! protein-DNA complex assembly GO:0065004 134 92 1,000 4,161E-03 0,12396363 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 4,25E-03 0,12508003 GO:0010498|proteasomal protein catabolic process, ! nucleosome organization GO:0034728 143 95 1,000 4,43E-03 0,12882504 ! ATP biosynthetic process GO:0006754 197 95 1,000 4,43E-03 0,12730945 ! response to protein stimulus GO:0051789 158 96 1,000 4,521E-03 0,12842244 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 5,194E-03 0,14585787 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,194E-03 0,14420039 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,194E-03 0,14258016 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,194E-03 0,14099594 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,194E-03 0,13944653 ! neuron fate determination GO:0048664 7 5 0,000 5,194E-03 0,13793081 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,194E-03 0,13644768 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,194E-03 0,13499611 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,194E-03 0,1335751 ! polyol transport GO:0015791 12 5 0,000 5,194E-03 0,13218369 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,194E-03 0,13082097 ! response to superoxide GO:0000303 10 5 0,000 5,194E-03 0,12948607 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,194E-03 0,12817813 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,194E-03 0,12689635 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,194E-03 0,12563995 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,194E-03 0,12440818 ! female meiosis GO:0007143 10 5 0,000 5,194E-03 0,12320034 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,194E-03 0,12201572 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,194E-03 0,12085366 ! hypothalamus development GO:0021854 9 5 0,000 5,194E-03 0,11971353 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,194E-03 0,11859472 ! cobalt ion transport GO:0006824 11 5 0,000 5,194E-03 0,11749662 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,194E-03 0,11641867 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,194E-03 0,11536031 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,194E-03 0,11432103 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,194E-03 0,11330031 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,194E-03 0,11229765 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,194E-03 0,11131258 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,194E-03 0,11034465 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,194E-03 0,1093934 ! transposition GO:0032196 9 5 0,000 5,194E-03 0,10845841 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,194E-03 0,10753928 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,194E-03 0,10663558 ! negative chemotaxis GO:0050919 16 5 0,000 5,194E-03 0,10574695 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,194E-03 0,10487301 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,194E-03 0,1040134 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,194E-03 0,10316776 ! behavioral response to pain GO:0048266 10 5 0,000 5,194E-03 0,10233576 ! clathrin coat assembly GO:0048268 15 5 0,000 5,194E-03 0,10151708 ! Notch receptor processing GO:0007220 11 5 0,000 5,194E-03 0,10071138 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,194E-03 0,09991838 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,194E-03 0,09913777 ! micturition GO:0060073 9 5 0,000 5,194E-03 0,09836926 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,194E-03 0,09761257 ! copulation GO:0007620 9 5 0,000 5,194E-03 0,09686744 ! glial cell fate commitment GO:0021781 14 5 0,000 5,194E-03 0,09613359 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,194E-03 0,09541079 ! bioluminescence GO:0008218 9 5 0,000 5,194E-03 0,09469876 ! spermidine metabolic process GO:0008216 7 5 0,000 5,194E-03 0,09399729 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,194E-03 0,09330614 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,194E-03 0,09262507 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,194E-03 0,09195387 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,194E-03 0,09129233 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,194E-03 0,09064025 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,194E-03 0,08999741 ! grooming behavior GO:0007625 6 5 0,000 5,194E-03 0,08936362 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,194E-03 0,0887387 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,194E-03 0,08812246 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,194E-03 0,08751472 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,194E-03 0,0869153 ! response to protozoan GO:0001562 13 5 0,000 5,194E-03 0,08632404 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,194E-03 0,08574077 ! lymph vessel development GO:0001945 10 5 0,000 5,194E-03 0,08516533 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,194E-03 0,08459756 ! endochondral ossification GO:0001958 17 5 0,000 5,194E-03 0,08403731 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,194E-03 0,08348444 ! single strand break repair GO:0000012 8 5 0,000 5,194E-03 0,08293879 ! parathyroid gland development GO:0060017 14 5 0,000 5,194E-03 0,08240022 ! anagen GO:0042640 7 5 0,000 5,194E-03 0,08186861 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,194E-03 0,08134381 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,194E-03 0,0808257 ! cytokine secretion GO:0050663 15 5 0,000 5,194E-03 0,08031414 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,194E-03 0,07980902 ! ceramide catabolic process GO:0046514 7 5 0,000 5,194E-03 0,07931022 ! skeletal myofibril assembly GO:0014866 12 5 0,000 5,194E-03 0,07881761 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,194E-03 0,07833108 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,194E-03 0,07785052 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,194E-03 0,07737582 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,194E-03 0,07690688 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,194E-03 0,07644358 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,194E-03 0,07598584 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,194E-03 0,07553354 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,194E-03 0,07508659 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,194E-03 0,07464491 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,194E-03 0,07420839 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,194E-03 0,07377694 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,194E-03 0,07335049 ! microvillus organization GO:0032528 8 5 0,000 5,194E-03 0,07292893 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,194E-03 0,0725122 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,194E-03 0,0721002 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,194E-03 0,07169285 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,194E-03 0,07129008 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,194E-03 0,07089181 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,194E-03 0,07049797 ! polyol catabolic process GO:0046174 9 5 0,000 5,194E-03 0,07010848 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 5,194E-03 0,06972327 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,194E-03 0,06934227 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,194E-03 0,0689654 ! muscle cell migration GO:0014812 8 5 0,000 5,194E-03 0,06859262 ! mitochondrial fission GO:0000266 8 5 0,000 5,194E-03 0,06822384 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,194E-03 0,06785901 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,194E-03 0,06749806 ! mRNA transcription GO:0009299 10 5 0,000 5,194E-03 0,06714092 ! nerve growth factor processing GO:0032455 9 5 0,000 5,194E-03 0,06678755 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,194E-03 0,06643788 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,194E-03 0,06609185 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,194E-03 0,0657494 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,194E-03 0,06541049 ! monocyte activation GO:0042117 10 5 0,000 5,194E-03 0,06507505 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,194E-03 0,06474303 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,194E-03 0,06441439 ! response to food GO:0032094 6 5 0,000 5,194E-03 0,06408906 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,194E-03 0,06376701 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,194E-03 0,06344817 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,194E-03 0,06313251 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,194E-03 0,06281997 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,194E-03 0,06251051 ! forebrain neuron development GO:0021884 13 5 0,000 5,194E-03 0,06220409 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,194E-03 0,06190066 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,194E-03 0,06160017 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,194E-03 0,06130258 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,194E-03 0,06100786 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,194E-03 0,06071595 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,194E-03 0,06042683 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,194E-03 0,06014045 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,194E-03 0,05985677 ! lipid glycosylation GO:0030259 7 5 0,000 5,194E-03 0,05957575 ! nucleobase transport GO:0015851 6 5 0,000 5,194E-03 0,05929736 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,194E-03 0,05902156 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,194E-03 0,05874831 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,194E-03 0,05847758 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,194E-03 0,05820933 ! basic amino acid transport GO:0015802 12 5 0,000 5,194E-03 0,05794354 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,194E-03 0,05768016 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,194E-03 0,05741916 ! actin nucleation GO:0045010 11 5 0,000 5,194E-03 0,05716052 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,194E-03 0,05690419 ! depurination GO:0045007 5 5 0,000 5,194E-03 0,05665015 ! depyrimidination GO:0045008 10 5 0,000 5,194E-03 0,05639838 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,194E-03 0,05614883 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,194E-03 0,05590147 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,194E-03 0,05565629 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,194E-03 0,05541325 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,194E-03 0,05517232 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,194E-03 0,05493348 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,194E-03 0,0546967 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,194E-03 0,05446195 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,194E-03 0,05422921 ! activated T cell proliferation GO:0050798 16 5 0,000 5,194E-03 0,05399844 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,194E-03 0,05376964 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,194E-03 0,05354276 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,194E-03 0,05331779 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,194E-03 0,05309471 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,194E-03 0,05287348 ! response to arsenic GO:0046685 11 5 0,000 5,194E-03 0,05265409 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,194E-03 0,05243651 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,194E-03 0,05222072 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,194E-03 0,0520067 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,194E-03 0,05179443 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,194E-03 0,05158388 ! response to mercury ion GO:0046689 8 5 0,000 5,194E-03 0,05137504 ! response to cadmium ion GO:0046686 7 5 0,000 5,194E-03 0,05116788 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,194E-03 0,05096239 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,194E-03 0,05075854 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 5,194E-03 0,05055631 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,194E-03 0,05035569 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,194E-03 0,05015666 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,194E-03 0,04995919 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,194E-03 0,04976327 ! decidualization GO:0046697 11 5 0,000 5,194E-03 0,04956888 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,194E-03 0,04937601 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,194E-03 0,04918463 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,194E-03 0,04899473 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,194E-03 0,04880629 ! embryonic cleavage GO:0040016 6 5 0,000 5,194E-03 0,04861929 ! peroxisome fission GO:0016559 5 5 0,000 5,194E-03 0,04843372 ! histone demethylation GO:0016577 13 5 0,000 5,194E-03 0,04824956 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,194E-03 0,0480668 ! mitotic recombination GO:0006312 9 5 0,000 5,194E-03 0,04788541 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,194E-03 0,04770539 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,194E-03 0,04752672 ! metaphase plate congression GO:0051310 7 5 0,000 5,194E-03 0,04734938 ! regulation of sterol transport GO:0032371 7 5 0,000 5,194E-03 0,04717336 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,194E-03 0,04699865 ! enteric nervous system development GO:0048484 8 5 0,000 5,194E-03 0,04682522 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,194E-03 0,04665307 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,194E-03 0,04648218 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,194E-03 0,04631253 ! muscle cell proliferation GO:0033002 12 5 0,000 5,194E-03 0,04614413 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,194E-03 0,04597694 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,194E-03 0,04581095 ! B cell homeostasis GO:0001782 13 5 0,000 5,194E-03 0,04564617 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,194E-03 0,04548256 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,194E-03 0,04532012 ! metaphase GO:0051323 11 5 0,000 5,194E-03 0,04515884 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,194E-03 0,0449987 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,194E-03 0,0448397 ! cellular response to nutrient GO:0031670 8 5 0,000 5,194E-03 0,04468181 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,194E-03 0,04452503 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,194E-03 0,04436935 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,194E-03 0,04421475 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,194E-03 0,04406123 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,194E-03 0,04390877 ! response to redox state GO:0051775 6 5 0,000 5,194E-03 0,04375736 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,194E-03 0,04360699 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,194E-03 0,04345765 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,194E-03 0,04330933 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,194E-03 0,04316202 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,194E-03 0,04301571 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,194E-03 0,04287039 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,194E-03 0,04272604 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,194E-03 0,04258267 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,194E-03 0,04244025 ! striatum development GO:0021756 14 5 0,000 5,194E-03 0,04229878 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,194E-03 0,04215825 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,194E-03 0,04201866 ! glial cell migration GO:0008347 10 5 0,000 5,194E-03 0,04187998 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,194E-03 0,04174222 ! neural plate morphogenesis GO:0001839 7 5 0,000 5,194E-03 0,04160536 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,194E-03 0,04146939 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,194E-03 0,04133431 ! T cell activation during immune response GO:0002286 9 5 0,000 5,194E-03 0,04120011 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,194E-03 0,04106678 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,194E-03 0,0409343 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,194E-03 0,04080268 ! neuroprotection GO:0043526 8 5 0,000 5,194E-03 0,04067191 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,194E-03 0,04054196 ! regulation of sensory perception GO:0051931 8 5 0,000 5,194E-03 0,04041285 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,194E-03 0,04028455 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,194E-03 0,04015707 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,194E-03 0,04003039 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,194E-03 0,03990451 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,194E-03 0,03977942 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,194E-03 0,03965511 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,194E-03 0,03953157 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,194E-03 0,0394088 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,194E-03 0,03928679 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,194E-03 0,03916554 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,194E-03 0,03904503 ! spindle assembly GO:0051225 6 5 0,000 5,194E-03 0,03892526 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,194E-03 0,03880622 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,194E-03 0,03868791 ! protein palmitoylation GO:0018345 12 5 0,000 5,194E-03 0,03857032 ! drug metabolic process GO:0017144 7 5 0,000 5,194E-03 0,03845344 ! stem cell division GO:0017145 11 5 0,000 5,194E-03 0,03833726 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,194E-03 0,03822179 ! organ regeneration GO:0031100 7 5 0,000 5,194E-03 0,03810701 ! carnitine metabolic process GO:0009437 8 5 0,000 5,194E-03 0,03799292 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,194E-03 0,03787951 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,23E-03 0,04529719 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,23E-03 0,04516277 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 6,23E-03 0,04502915 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 6,23E-03 0,04489633 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,23E-03 0,04476428 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 6,23E-03 0,044633 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 6,23E-03 0,0445025 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,23E-03 0,04437275 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 6,23E-03 0,04424376 ! response to oxygen radical GO:0000305 11 6 0,000 6,23E-03 0,04411552 ! positive regulation of axon extension GO:0045773 13 6 0,000 6,23E-03 0,04398802 ! myoblast cell fate commitment GO:0048625 18 6 0,000 6,23E-03 0,04386125 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 6,23E-03 0,04373521 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 6,23E-03 0,0436099 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,23E-03 0,0434853 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,23E-03 0,04336141 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 6,23E-03 0,04323822 ! forebrain regionalization GO:0021871 9 6 0,000 6,23E-03 0,04311573 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,23E-03 0,04299394 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,23E-03 0,04287283 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 6,23E-03 0,0427524 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,23E-03 0,04263265 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 6,23E-03 0,04251356 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 6,23E-03 0,04239514 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,23E-03 0,04227737 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 6,23E-03 0,04216026 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 6,23E-03 0,0420438 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,23E-03 0,04192797 ! malate metabolic process GO:0006108 13 6 0,000 6,23E-03 0,04181279 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 6,23E-03 0,04169823 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 6,23E-03 0,0415843 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 6,23E-03 0,04147099 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 6,23E-03 0,0413583 ! protein refolding GO:0042026 15 6 0,000 6,23E-03 0,04124622 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,23E-03 0,04113474 ! opsonization GO:0008228 8 6 0,000 6,23E-03 0,04102387 ! mating behavior GO:0007617 7 6 0,000 6,23E-03 0,04091359 ! erythrocyte maturation GO:0043249 8 6 0,000 6,23E-03 0,0408039 ! embryonic hemopoiesis GO:0035162 16 6 0,000 6,23E-03 0,0406948 ! protein amino acid dealkylation GO:0008214 15 6 0,000 6,23E-03 0,04058628 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 6,23E-03 0,04047834 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 6,23E-03 0,04037097 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,23E-03 0,04026416 ! response to interferon-gamma GO:0034341 16 6 0,000 6,23E-03 0,04015793 ! toxin metabolic process GO:0009404 11 6 0,000 6,23E-03 0,04005225 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,23E-03 0,03994712 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 6,23E-03 0,03984255 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 6,23E-03 0,03973852 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 6,23E-03 0,03963504 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 6,23E-03 0,03953209 ! cGMP-mediated signaling GO:0019934 14 6 0,000 6,23E-03 0,03942967 ! dorsal spinal cord development GO:0021516 10 6 0,000 6,23E-03 0,03932779 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,23E-03 0,03922643 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 6,23E-03 0,03912559 ! thymic T cell selection GO:0045061 16 6 0,000 6,23E-03 0,03902527 ! sphingoid catabolic process GO:0046521 8 6 0,000 6,23E-03 0,03892546 ! protein lipoylation GO:0009249 10 6 0,000 6,23E-03 0,03882616 ! transepithelial chloride transport GO:0030321 12 6 0,000 6,23E-03 0,03872736 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 6,23E-03 0,03862907 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,23E-03 0,03853128 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 6,23E-03 0,03843398 ! glutamate catabolic process GO:0006538 12 6 0,000 6,23E-03 0,03833716 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 6,23E-03 0,03824084 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,23E-03 0,038145 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 6,23E-03 0,03804964 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,23E-03 0,03795475 ! hyperosmotic response GO:0006972 10 6 0,000 6,23E-03 0,03786033 ! L-serine biosynthetic process GO:0006564 7 6 0,000 6,23E-03 0,03776639 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 6,23E-03 0,03767291 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 6,23E-03 0,03757989 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,23E-03 0,03748733 ! urea metabolic process GO:0019627 7 6 0,000 6,23E-03 0,03739522 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,23E-03 0,03730356 ! neutrophil activation GO:0042119 7 6 0,000 6,23E-03 0,03721236 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,23E-03 0,0371216 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 6,23E-03 0,03703128 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,23E-03 0,03694139 ! paraxial mesoderm development GO:0048339 16 6 0,000 6,23E-03 0,03685195 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 6,23E-03 0,03676293 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,23E-03 0,03667435 ! neuron apoptosis GO:0051402 15 6 0,000 6,23E-03 0,03658619 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,23E-03 0,03649845 ! T cell mediated immunity GO:0002456 17 6 0,000 6,23E-03 0,03641113 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,23E-03 0,03632423 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 6,23E-03 0,03623775 ! carnitine transport GO:0015879 10 6 0,000 6,23E-03 0,03615167 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,23E-03 0,03606601 ! positive regulation of exocytosis GO:0045921 11 6 0,000 6,23E-03 0,03598074 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 6,23E-03 0,03589588 ! early endosome to late endosome transport GO:0045022 16 6 0,000 6,23E-03 0,03581142 ! 5S class rRNA transcription GO:0042791 13 6 0,000 6,23E-03 0,03572736 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,23E-03 0,03564369 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 6,23E-03 0,03556041 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 6,23E-03 0,03547752 ! sodium ion homeostasis GO:0055078 12 6 0,000 6,23E-03 0,03539501 ! establishment of spindle localization GO:0051293 16 6 0,000 6,23E-03 0,03531289 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 6,23E-03 0,03523114 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,23E-03 0,03514978 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 6,23E-03 0,03506879 ! response to UV-C GO:0010225 14 6 0,000 6,23E-03 0,03498817 ! astrocyte development GO:0014002 16 6 0,000 6,23E-03 0,03490792 ! protein targeting to lysosome GO:0006622 12 6 0,000 6,23E-03 0,03482804 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,23E-03 0,03474853 ! interaction with symbiont GO:0051702 14 6 0,000 6,23E-03 0,03466937 ! regulation of dendrite development GO:0050773 16 6 0,000 6,23E-03 0,03459058 ! peptidyl-arginine modification GO:0018195 13 6 0,000 6,23E-03 0,03451214 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 6,23E-03 0,03443406 ! response to copper ion GO:0046688 10 6 0,000 6,23E-03 0,03435633 ! response to exogenous dsRNA GO:0043330 13 6 0,000 6,23E-03 0,03427895 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 6,23E-03 0,03420192 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,23E-03 0,03412523 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 6,23E-03 0,03404889 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,23E-03 0,03397289 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 6,23E-03 0,03389723 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,23E-03 0,0338219 ! nucleoside catabolic process GO:0009164 10 6 0,000 6,23E-03 0,03374691 ! hair follicle maturation GO:0048820 8 6 0,000 6,23E-03 0,03367224 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,23E-03 0,03359791 ! Schwann cell development GO:0014044 15 6 0,000 6,23E-03 0,03352391 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 6,23E-03 0,03345023 ! response to pheromone GO:0019236 6 6 0,000 6,23E-03 0,03337687 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 6,23E-03 0,03330384 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 6,23E-03 0,03323112 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 6,23E-03 0,03315872 ! base conversion or substitution editing GO:0016553 6 6 0,000 6,23E-03 0,03308664 ! subpallium development GO:0021544 15 6 0,000 6,23E-03 0,03301487 ! neural tube patterning GO:0021532 8 6 0,000 6,23E-03 0,03294341 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 6,23E-03 0,03287226 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 6,23E-03 0,03280141 ! maintenance of organ identity GO:0048496 9 6 0,000 6,23E-03 0,03273087 ! G2 phase GO:0051319 16 6 0,000 6,23E-03 0,03266063 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 6,23E-03 0,03259069 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 6,23E-03 0,03252106 ! oxygen homeostasis GO:0032364 10 6 0,000 6,23E-03 0,03245172 ! establishment of planar polarity GO:0001736 7 6 0,000 6,23E-03 0,03238267 ! regulation of mast cell activation GO:0033003 13 6 0,000 6,23E-03 0,03231392 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,23E-03 0,03224545 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 6,23E-03 0,03217728 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,23E-03 0,0321094 ! receptor internalization GO:0031623 11 6 0,000 6,23E-03 0,0320418 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,23E-03 0,03197448 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 6,23E-03 0,03190745 ! neutrophil homeostasis GO:0001780 11 6 0,000 6,23E-03 0,0318407 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,23E-03 0,03177423 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 6,23E-03 0,03170803 ! protein deubiquitination GO:0016579 16 6 0,000 6,23E-03 0,03164211 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 6,23E-03 0,03157646 ! protein destabilization GO:0031648 9 6 0,000 6,23E-03 0,03151109 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 6,23E-03 0,03144598 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,23E-03 0,03138114 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 6,23E-03 0,03131657 ! regulation of viral transcription GO:0046782 11 6 0,000 6,23E-03 0,03125227 ! progesterone metabolic process GO:0042448 12 6 0,000 6,23E-03 0,03118823 ! negative regulation of axon extension GO:0030517 24 6 0,000 6,23E-03 0,03112445 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 6,23E-03 0,03106093 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 6,23E-03 0,03099767 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,23E-03 0,03093466 ! determination of adult lifespan GO:0008340 17 6 0,000 6,23E-03 0,03087192 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 6,23E-03 0,03080942 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 6,23E-03 0,03074718 ! neural plate development GO:0001840 9 6 0,000 6,23E-03 0,03068519 ! catecholamine transport GO:0051937 9 6 0,000 6,23E-03 0,03062345 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 6,23E-03 0,03056196 ! sensory cilium assembly GO:0035058 10 6 0,000 6,23E-03 0,03050071 ! organ or tissue specific immune response GO:0002251 8 6 0,000 6,23E-03 0,03043971 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 6,23E-03 0,03037895 ! maternal placenta development GO:0001893 12 6 0,000 6,23E-03 0,03031843 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 6,23E-03 0,03025816 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,23E-03 0,03019812 ! negative regulation of B cell activation GO:0050869 14 6 0,000 6,23E-03 0,03013833 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 6,23E-03 0,03007876 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 6,23E-03 0,03001944 ! positive regulation of coagulation GO:0050820 13 6 0,000 6,23E-03 0,02996034 ! cellular anion homeostasis GO:0030002 11 6 0,000 6,23E-03 0,02990148 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 7,265E-03 0,03479904 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 7,265E-03 0,03473094 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 7,265E-03 0,03466311 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,265E-03 0,03459554 ! regulation of helicase activity GO:0051095 16 7 0,000 7,265E-03 0,03452823 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 7,265E-03 0,03446119 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 7,265E-03 0,0343944 ! sleep GO:0030431 16 7 0,000 7,265E-03 0,03432787 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,265E-03 0,0342616 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 7,265E-03 0,03419559 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,265E-03 0,03412983 ! prostate gland development GO:0030850 14 7 0,000 7,265E-03 0,03406432 ! nucleotide-sugar transport GO:0015780 11 7 0,000 7,265E-03 0,03399906 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,265E-03 0,03393406 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,265E-03 0,0338693 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 7,265E-03 0,03380478 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,265E-03 0,03374052 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 7,265E-03 0,03367649 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 7,265E-03 0,03361271 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,265E-03 0,03354917 ! SMAD protein complex assembly GO:0007183 13 7 0,000 7,265E-03 0,03348587 ! glycolipid transport GO:0046836 11 7 0,000 7,265E-03 0,03342281 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,265E-03 0,03335998 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,265E-03 0,03329739 ! neuron adhesion GO:0007158 14 7 0,000 7,265E-03 0,03323504 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 7,265E-03 0,03317292 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,265E-03 0,03311103 ! establishment of tissue polarity GO:0007164 8 7 0,000 7,265E-03 0,03304937 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 7,265E-03 0,03298794 ! mRNA stabilization GO:0048255 18 7 0,000 7,265E-03 0,03292674 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 7,265E-03 0,03286576 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 7,265E-03 0,03280501 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 7,265E-03 0,03274449 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 7,265E-03 0,03268418 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,265E-03 0,0326241 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,265E-03 0,03256424 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,265E-03 0,0325046 ! lipoprotein transport GO:0042953 14 7 0,000 7,265E-03 0,03244518 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,265E-03 0,03238597 ! rhythmic behavior GO:0007622 17 7 0,000 7,265E-03 0,03232698 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 7,265E-03 0,0322682 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 7,265E-03 0,03220964 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 7,265E-03 0,03215129 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 7,265E-03 0,03209315 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,265E-03 0,03203522 ! regulation of odontogenesis GO:0042481 14 7 0,000 7,265E-03 0,0319775 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,265E-03 0,03191998 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 7,265E-03 0,03186268 ! mechanosensory behavior GO:0007638 16 7 0,000 7,265E-03 0,03180558 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 7,265E-03 0,03174868 ! positive regulation of isotype switching GO:0045830 17 7 0,000 7,265E-03 0,03169198 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 7,265E-03 0,03163549 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 7,265E-03 0,0315792 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,265E-03 0,03152311 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,265E-03 0,03146722 ! spinal cord patterning GO:0021511 14 7 0,000 7,265E-03 0,03141152 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 7,265E-03 0,03135603 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 7,265E-03 0,03130073 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,265E-03 0,03124562 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 7,265E-03 0,0311907 ! adrenal gland development GO:0030325 17 7 0,000 7,265E-03 0,03113598 ! cysteine metabolic process GO:0006534 13 7 0,000 7,265E-03 0,03108146 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 7,265E-03 0,03102712 ! ovulation GO:0030728 10 7 0,000 7,265E-03 0,03097297 ! adenohypophysis development GO:0021984 11 7 0,000 7,265E-03 0,03091901 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 7,265E-03 0,03086524 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 7,265E-03 0,03081165 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 7,265E-03 0,03075825 ! microtubule nucleation GO:0007020 21 7 0,000 7,265E-03 0,03070504 ! proline biosynthetic process GO:0006561 10 7 0,000 7,265E-03 0,03065201 ! tryptophan metabolic process GO:0006568 11 7 0,000 7,265E-03 0,03059916 ! thyroid hormone generation GO:0006590 13 7 0,000 7,265E-03 0,03054649 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 7,265E-03 0,03049401 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 7,265E-03 0,0304417 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,265E-03 0,03038957 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 7,265E-03 0,03033763 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 7,265E-03 0,03028586 ! galactose metabolic process GO:0006012 13 7 0,000 7,265E-03 0,03023426 ! vesicle fusion GO:0006906 20 7 0,000 7,265E-03 0,03018284 ! response to dietary excess GO:0002021 8 7 0,000 7,265E-03 0,0301316 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,265E-03 0,03008053 ! intracellular pH reduction GO:0051452 13 7 0,000 7,265E-03 0,03002963 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,265E-03 0,0299789 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 7,265E-03 0,02992835 ! organ growth GO:0035265 15 7 0,000 7,265E-03 0,02987796 ! nucleoside transport GO:0015858 11 7 0,000 7,265E-03 0,02982775 ! nucleoside salvage GO:0043174 11 7 0,000 7,265E-03 0,0297777 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 7,265E-03 0,02972782 ! male sex determination GO:0030238 15 7 0,000 7,265E-03 0,02967811 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 7,265E-03 0,02962857 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 7,265E-03 0,02957919 ! parturition GO:0007567 16 7 0,000 7,265E-03 0,02952997 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 7,265E-03 0,02948092 ! rRNA modification GO:0000154 14 7 0,000 7,265E-03 0,02943203 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 7,265E-03 0,0293833 ! spindle checkpoint GO:0031577 16 7 0,000 7,265E-03 0,02933473 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 7,265E-03 0,02928632 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 7,265E-03 0,02923807 ! monocyte differentiation GO:0030224 16 7 0,000 7,265E-03 0,02918999 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 7,265E-03 0,02914205 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,265E-03 0,02909428 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 7,265E-03 0,02904666 ! hyaluronan metabolic process GO:0030212 9 7 0,000 7,265E-03 0,0289992 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 7,265E-03 0,02895189 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,265E-03 0,02890474 ! fibrinolysis GO:0042730 11 7 0,000 7,265E-03 0,02885774 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 7,265E-03 0,02881089 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,265E-03 0,0287642 ! eating behavior GO:0042755 8 7 0,000 7,265E-03 0,02871766 ! B cell lineage commitment GO:0002326 21 7 0,000 7,265E-03 0,02867126 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,265E-03 0,02862502 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 7,265E-03 0,02857892 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 7,265E-03 0,02853298 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,265E-03 0,02848718 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 7,265E-03 0,02844152 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,265E-03 0,02839602 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 7,265E-03 0,02835066 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 7,265E-03 0,02830544 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 7,265E-03 0,02826037 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 7,265E-03 0,02821544 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,265E-03 0,02817065 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 7,265E-03 0,02812601 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,265E-03 0,0280815 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,265E-03 0,02803714 ! histone ubiquitination GO:0016574 9 7 0,000 7,265E-03 0,02799292 ! regulation of meiosis GO:0040020 12 7 0,000 7,265E-03 0,02794884 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 7,265E-03 0,02790489 ! T cell lineage commitment GO:0002360 16 7 0,000 7,265E-03 0,02786108 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 7,265E-03 0,02781742 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,265E-03 0,02777388 ! membrane to membrane docking GO:0022614 14 7 0,000 7,265E-03 0,02773049 ! transcription termination GO:0006353 14 7 0,000 7,265E-03 0,02768722 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,265E-03 0,0276441 ! anaphase GO:0051322 18 7 0,000 7,265E-03 0,02760111 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 7,265E-03 0,02755825 ! axonal fasciculation GO:0007413 19 7 0,000 7,265E-03 0,02751552 ! negative regulation of nuclear division GO:0051784 15 7 0,000 7,265E-03 0,02747293 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 7,265E-03 0,02743047 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 7,265E-03 0,02738813 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 7,265E-03 0,02734593 ! diuresis GO:0030146 12 7 0,000 7,265E-03 0,02730386 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,265E-03 0,02726192 ! thiamin metabolic process GO:0006772 7 7 0,000 7,265E-03 0,02722011 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,265E-03 0,02717842 ! antibiotic transport GO:0042891 9 7 0,000 7,265E-03 0,02713687 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,265E-03 0,02709544 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 7,265E-03 0,02705413 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 7,265E-03 0,02701295 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 7,265E-03 0,0269719 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 7,265E-03 0,02693097 ! melanin biosynthetic process GO:0042438 10 7 0,000 7,265E-03 0,02689017 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 7,265E-03 0,02684949 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,265E-03 0,02680893 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,265E-03 0,02676849 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 7,265E-03 0,02672818 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 7,265E-03 0,02668799 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 7,265E-03 0,02664791 ! endosome to lysosome transport GO:0008333 12 7 0,000 7,265E-03 0,02660796 ! protein modification by small protein removal GO:0070646 19 7 0,000 7,265E-03 0,02656813 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 7,265E-03 0,02652842 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 7,265E-03 0,02648882 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 7,265E-03 0,02644935 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 7,265E-03 0,02640999 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,265E-03 0,02637074 ! muscle adaptation GO:0043500 13 7 0,000 7,265E-03 0,02633162 ! embryonic heart tube development GO:0035050 14 7 0,000 7,265E-03 0,02629261 ! retina homeostasis GO:0001895 12 7 0,000 7,265E-03 0,02625371 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 7,265E-03 0,02621494 ! protein amino acid prenylation GO:0018346 19 7 0,000 7,265E-03 0,02617627 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 7,265E-03 0,02613772 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 7,265E-03 0,02609928 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 8,298E-03 0,02976888 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 8,298E-03 0,02972523 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 8,298E-03 0,02968171 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 8,298E-03 0,02963831 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 8,298E-03 0,02959505 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,298E-03 0,02955191 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,298E-03 0,02950889 ! male meiosis GO:0007140 9 8 0,000 8,298E-03 0,029466 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 8,298E-03 0,02942323 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 8,298E-03 0,02938059 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 8,298E-03 0,02933807 ! meiotic prophase I GO:0007128 14 8 0,000 8,298E-03 0,02929568 ! response to zinc ion GO:0010043 12 8 0,000 8,298E-03 0,0292534 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 8,298E-03 0,02921125 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,298E-03 0,02916922 ! oligopeptide transport GO:0006857 16 8 0,000 8,298E-03 0,02912731 ! actin-myosin filament sliding GO:0033275 13 8 0,000 8,298E-03 0,02908552 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 8,298E-03 0,02904385 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 8,298E-03 0,0290023 ! signal peptide processing GO:0006465 12 8 0,000 8,298E-03 0,02896087 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 8,298E-03 0,02891955 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 8,298E-03 0,02887836 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,298E-03 0,02883728 ! succinate metabolic process GO:0006105 17 8 0,000 8,298E-03 0,02879632 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 8,298E-03 0,02875547 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,298E-03 0,02871474 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,298E-03 0,02867413 ! estrogen metabolic process GO:0008210 17 8 0,000 8,298E-03 0,02863363 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 8,298E-03 0,02859324 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,298E-03 0,02855297 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 8,298E-03 0,02851281 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,298E-03 0,02847276 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,298E-03 0,02843283 ! reflex GO:0060004 17 8 0,000 8,298E-03 0,02839301 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,298E-03 0,0283533 ! glycerolipid catabolic process GO:0046503 14 8 0,000 8,298E-03 0,0283137 ! hemoglobin metabolic process GO:0020027 14 8 0,000 8,298E-03 0,02827421 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,298E-03 0,02823483 ! pigment granule organization GO:0048753 17 8 0,000 8,298E-03 0,02819556 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,298E-03 0,0281564 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 8,298E-03 0,02811735 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 8,298E-03 0,0280784 ! astrocyte differentiation GO:0048708 19 8 0,000 8,298E-03 0,02803957 ! histidine catabolic process GO:0006548 10 8 0,000 8,298E-03 0,02800084 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,298E-03 0,02796222 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 8,298E-03 0,0279237 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 8,298E-03 0,02788529 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 8,298E-03 0,02784699 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 8,298E-03 0,02780879 ! regulation of pigmentation during development GO:0048070 25 8 0,000 8,298E-03 0,02777069 ! melanin metabolic process GO:0006582 17 8 0,000 8,298E-03 0,0277327 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 8,298E-03 0,02769482 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 8,298E-03 0,02765704 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 8,298E-03 0,02761936 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,298E-03 0,02758178 ! macrophage activation GO:0042116 13 8 0,000 8,298E-03 0,0275443 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,298E-03 0,02750693 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,298E-03 0,02746966 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 8,298E-03 0,02743249 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,298E-03 0,02739542 ! purine salvage GO:0043101 12 8 0,000 8,298E-03 0,02735844 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 8,298E-03 0,02732157 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,298E-03 0,0272848 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 8,298E-03 0,02724813 ! osteoblast development GO:0002076 17 8 0,000 8,298E-03 0,02721155 ! positive regulation of vasodilation GO:0045909 14 8 0,000 8,298E-03 0,02717508 ! negative regulation of translational initiation GO:0045947 12 8 0,000 8,298E-03 0,0271387 ! Schwann cell differentiation GO:0014037 21 8 0,000 8,298E-03 0,02710242 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 8,298E-03 0,02706623 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,298E-03 0,02703014 ! response to UV-B GO:0010224 17 8 0,000 8,298E-03 0,02699415 ! protein targeting to vacuole GO:0006623 14 8 0,000 8,298E-03 0,02695825 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,298E-03 0,02692245 ! intermediate filament organization GO:0045109 12 8 0,000 8,298E-03 0,02688675 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 8,298E-03 0,02685114 ! cellular extravasation GO:0045123 13 8 0,000 8,298E-03 0,02681562 ! cardiac muscle cell development GO:0055013 14 8 0,000 8,298E-03 0,02678019 ! response to antibiotic GO:0046677 11 8 0,000 8,298E-03 0,02674486 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 8,298E-03 0,02670963 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 8,298E-03 0,02667448 ! DNA topological change GO:0006265 12 8 0,000 8,298E-03 0,02663943 ! response to tropane GO:0014073 15 8 0,000 8,298E-03 0,02660447 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 8,298E-03 0,0265696 ! melanosome transport GO:0032402 13 8 0,000 8,298E-03 0,02653483 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 8,298E-03 0,02650014 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 8,298E-03 0,02646554 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,298E-03 0,02643104 ! mast cell activation GO:0045576 14 8 0,000 8,298E-03 0,02639662 ! multicellular organismal aging GO:0010259 20 8 0,000 8,298E-03 0,0263623 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 8,298E-03 0,02632806 ! gas homeostasis GO:0033483 14 8 0,000 8,298E-03 0,02629391 ! dendrite morphogenesis GO:0048813 14 8 0,000 8,298E-03 0,02625985 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 8,298E-03 0,02622588 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 8,298E-03 0,026192 ! nucleosome disassembly GO:0006337 14 8 0,000 8,298E-03 0,0261582 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,298E-03 0,02612449 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 8,298E-03 0,02609087 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,298E-03 0,02605734 ! establishment of chromosome localization GO:0051303 14 8 0,000 8,298E-03 0,02602389 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 8,298E-03 0,02599052 ! intracellular lipid transport GO:0032365 16 8 0,000 8,298E-03 0,02595724 ! response to tumor cell GO:0002347 16 8 0,000 8,298E-03 0,02592405 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,298E-03 0,02589094 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 8,298E-03 0,02585792 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 8,298E-03 0,02582498 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 8,298E-03 0,02579212 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,298E-03 0,02575935 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 8,298E-03 0,02572666 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 8,298E-03 0,02569405 ! hormone catabolic process GO:0042447 17 8 0,000 8,298E-03 0,02566153 ! glycolipid catabolic process GO:0019377 16 8 0,000 8,298E-03 0,02562909 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 8,298E-03 0,02559673 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 8,298E-03 0,02556445 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 8,298E-03 0,02553225 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,298E-03 0,02550013 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 8,298E-03 0,0254681 ! adult feeding behavior GO:0008343 10 8 0,000 8,298E-03 0,02543614 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 8,298E-03 0,02540427 ! ATP catabolic process GO:0006200 11 8 0,000 8,298E-03 0,02537247 ! blastocyst growth GO:0001832 19 8 0,000 8,298E-03 0,02534076 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,298E-03 0,02530912 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,298E-03 0,02527757 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 8,298E-03 0,02524609 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,298E-03 0,02521469 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 8,298E-03 0,02518336 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 8,298E-03 0,02515212 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 8,298E-03 0,02512095 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 8,298E-03 0,02508986 ! amino sugar catabolic process GO:0046348 11 8 0,000 8,298E-03 0,02505885 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 8,298E-03 0,02502791 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,298E-03 0,02499705 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 8,298E-03 0,02496627 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 8,298E-03 0,02493556 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,298E-03 0,02490492 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 8,298E-03 0,02487436 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 8,298E-03 0,02484388 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,298E-03 0,02481347 ! NAD biosynthetic process GO:0009435 17 8 0,000 8,298E-03 0,02478314 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 8,298E-03 0,02475288 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 8,298E-03 0,02472269 ! axon extension GO:0048675 16 9 0,000 9,331E-03 0,0277651 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,331E-03 0,02773132 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 9,331E-03 0,02769762 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 9,331E-03 0,02766401 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,331E-03 0,02763048 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 9,331E-03 0,02759703 ! cell proliferation in forebrain GO:0021846 18 9 0,000 9,331E-03 0,02756366 ! neutral lipid catabolic process GO:0046461 14 9 0,000 9,331E-03 0,02753037 ! reproductive behavior GO:0019098 22 9 0,000 9,331E-03 0,02749716 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,331E-03 0,02746403 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 9,331E-03 0,02743098 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 9,331E-03 0,02739801 ! UTP metabolic process GO:0046051 10 9 0,000 9,331E-03 0,02736512 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 9,331E-03 0,02733231 ! induction of positive chemotaxis GO:0050930 17 9 0,000 9,331E-03 0,02729958 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 9,331E-03 0,02726692 ! artery development GO:0060840 25 9 0,000 9,331E-03 0,02723434 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 9,331E-03 0,02720184 ! regulation of glycolysis GO:0006110 20 9 0,000 9,331E-03 0,02716942 ! cerebral cortex cell migration GO:0021795 18 9 0,000 9,331E-03 0,02713708 ! equilibrioception GO:0050957 20 9 0,000 9,331E-03 0,02710481 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 9,331E-03 0,02707262 ! chemosensory behavior GO:0007635 21 9 0,000 9,331E-03 0,0270405 ! microtubule bundle formation GO:0001578 22 9 0,000 9,331E-03 0,02700847 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,331E-03 0,0269765 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 9,331E-03 0,02694462 ! leukocyte degranulation GO:0043299 16 9 0,000 9,331E-03 0,0269128 ! ganglioside metabolic process GO:0001573 22 9 0,000 9,331E-03 0,02688107 ! negative regulation of endocytosis GO:0045806 12 9 0,000 9,331E-03 0,02684941 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 9,331E-03 0,02681782 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 9,331E-03 0,0267863 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,331E-03 0,02675487 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,331E-03 0,0267235 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 9,331E-03 0,02669221 ! protein targeting to ER GO:0045047 25 9 0,000 9,331E-03 0,02666099 ! ceramide biosynthetic process GO:0046513 20 9 0,000 9,331E-03 0,02662984 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 9,331E-03 0,02659877 ! T cell selection GO:0045058 27 9 0,000 9,331E-03 0,02656777 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 9,331E-03 0,02653684 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 9,331E-03 0,02650598 ! glycine catabolic process GO:0006546 15 9 0,000 9,331E-03 0,0264752 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 9,331E-03 0,02644448 ! endosome organization GO:0007032 20 9 0,000 9,331E-03 0,02641384 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 9,331E-03 0,02638327 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 9,331E-03 0,02635277 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,331E-03 0,02632234 ! mannose metabolic process GO:0006013 13 9 0,000 9,331E-03 0,02629198 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 9,331E-03 0,02626169 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 9,331E-03 0,02623147 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 9,331E-03 0,02620132 ! Rac protein signal transduction GO:0016601 20 9 0,000 9,331E-03 0,02617123 ! receptor clustering GO:0043113 20 9 0,000 9,331E-03 0,02614122 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 9,331E-03 0,02611128 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,331E-03 0,0260814 ! retinol metabolic process GO:0042572 20 9 0,000 9,331E-03 0,02605159 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 9,331E-03 0,02602186 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 9,331E-03 0,02599218 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 9,331E-03 0,02596258 ! macrophage differentiation GO:0030225 15 9 0,000 9,331E-03 0,02593304 ! oligodendrocyte development GO:0014003 11 9 0,000 9,331E-03 0,02590357 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 9,331E-03 0,02587417 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,331E-03 0,02584484 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 9,331E-03 0,02581557 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,331E-03 0,02578636 ! response to amine stimulus GO:0014075 13 9 0,000 9,331E-03 0,02575723 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,331E-03 0,02572816 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 9,331E-03 0,02569915 ! erythrocyte development GO:0048821 17 9 0,000 9,331E-03 0,02567021 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,331E-03 0,02564133 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 9,331E-03 0,02561252 ! renal water homeostasis GO:0003091 15 9 0,000 9,331E-03 0,02558378 ! postreplication repair GO:0006301 25 9 0,000 9,331E-03 0,0255551 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 9,331E-03 0,02552648 ! icosanoid secretion GO:0032309 15 9 0,000 9,331E-03 0,02549793 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,331E-03 0,02546944 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 9,331E-03 0,02544101 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 9,331E-03 0,02541265 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 9,331E-03 0,02538435 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,331E-03 0,02535611 ! sterol catabolic process GO:0016127 14 9 0,000 9,331E-03 0,02532794 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,331E-03 0,02529983 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 9,331E-03 0,02527178 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 9,331E-03 0,02524379 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 9,331E-03 0,02521587 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 9,331E-03 0,02518801 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 9,331E-03 0,0251602 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 9,331E-03 0,02513246 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 9,331E-03 0,02510479 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 9,331E-03 0,02507717 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 9,331E-03 0,02504961 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,331E-03 0,02502211 ! purine base metabolic process GO:0006144 25 9 0,000 9,331E-03 0,02499468 ! pigment granule transport GO:0051904 17 9 0,000 9,331E-03 0,0249673 ! regulation of telomere maintenance GO:0032204 17 9 0,000 9,331E-03 0,02493998 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 9,331E-03 0,02491273 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 9,331E-03 0,02488553 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,331E-03 0,02485839 ! regulation of amino acid transport GO:0051955 12 9 0,000 9,331E-03 0,02483131 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 9,331E-03 0,02480429 ! mitochondrion localization GO:0051646 18 9 0,000 9,331E-03 0,02477733 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01036231 0,02748657 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01036231 0,02745675 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01036231 0,02742701 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01036231 0,02739732 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01036231 0,02736771 ! associative learning GO:0008306 21 10 0,000 0,01036231 0,02733815 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01036231 0,02730866 ! phosphate transport GO:0006817 24 10 0,000 0,01036231 0,02727923 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01036231 0,02724987 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01036231 0,02722057 ! CTP metabolic process GO:0046036 11 10 0,000 0,01036231 0,02719133 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01036231 0,02716215 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01036231 0,02713304 ! GTP metabolic process GO:0046039 11 10 0,000 0,01036231 0,02710399 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01036231 0,027075 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01036231 0,02704608 ! social behavior GO:0035176 29 10 0,000 0,01036231 0,02701721 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01036231 0,02698841 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01036231 0,02695967 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01036231 0,02693099 ! androgen metabolic process GO:0008209 17 10 0,000 0,01036231 0,02690237 ! phospholipid efflux GO:0033700 19 10 0,000 0,01036231 0,02687381 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01036231 0,02684531 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01036231 0,02681687 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01036231 0,0267885 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01036231 0,02676018 ! lung alveolus development GO:0048286 26 10 0,000 0,01036231 0,02673192 ! pathogenesis GO:0009405 17 10 0,000 0,01036231 0,02670372 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01036231 0,02667558 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01036231 0,0266475 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01036231 0,02661948 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01036231 0,02659152 ! endoderm development GO:0007492 18 10 0,000 0,01036231 0,02656362 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01036231 0,02653577 ! arginine catabolic process GO:0006527 17 10 0,000 0,01036231 0,02650799 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01036231 0,02648026 ! proline metabolic process GO:0006560 13 10 0,000 0,01036231 0,02645259 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01036231 0,02642498 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01036231 0,02639742 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01036231 0,02636992 ! V(D)J recombination GO:0033151 34 10 0,000 0,01036231 0,02634248 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01036231 0,0263151 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01036231 0,02628778 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01036231 0,02626051 ! B cell proliferation GO:0042100 19 10 0,000 0,01036231 0,02623329 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01036231 0,02620614 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01036231 0,02617904 ! multicellular organism growth GO:0035264 19 10 0,000 0,01036231 0,02615199 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01036231 0,026125 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01036231 0,02609807 ! ruffle organization GO:0031529 17 10 0,000 0,01036231 0,02607119 ! epithelial cell development GO:0002064 21 10 0,000 0,01036231 0,02604437 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01036231 0,0260176 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01036231 0,02599089 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01036231 0,02596423 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01036231 0,02593763 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01036231 0,02591108 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01036231 0,02588459 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01036231 0,02585815 ! motor axon guidance GO:0008045 22 10 0,000 0,01036231 0,02583176 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01036231 0,02580543 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01036231 0,02577915 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01036231 0,02575293 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01036231 0,02572676 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01036231 0,02570064 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01036231 0,02567457 ! segment specification GO:0007379 15 10 0,000 0,01036231 0,02564856 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01036231 0,0256226 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01036231 0,02559669 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01036231 0,02557084 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01036231 0,02554503 ! response to dsRNA GO:0043331 23 10 0,000 0,01036231 0,02551928 ! DNA ligation GO:0006266 18 10 0,000 0,01036231 0,02549358 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01036231 0,02546794 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01036231 0,02544234 ! melanosome localization GO:0032400 16 10 0,000 0,01036231 0,0254168 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01036231 0,0253913 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01036231 0,02536586 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01036231 0,02534047 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01036231 0,02531513 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01036231 0,02528984 ! induction of an organ GO:0001759 17 10 0,000 0,01036231 0,0252646 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01036231 0,02523941 GO:0002263|cell activation during immune response, ! protein sumoylation GO:0016925 17 10 0,000 0,01036231 0,02521427 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01036231 0,02518918 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01036231 0,02516414 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01036231 0,02513915 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01036231 0,02511421 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01036231 0,02508932 ! salivary gland development GO:0007431 28 10 0,000 0,01036231 0,02506448 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01036231 0,02503969 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01036231 0,02501495 ! midbrain development GO:0030901 14 10 0,000 0,01036231 0,02499025 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01036231 0,02496561 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01036231 0,02494101 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01036231 0,02491646 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01036231 0,02489196 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01036231 0,02486751 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01036231 0,02484311 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01036231 0,02481875 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01036231 0,02479444 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01036231 0,02477018 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01036231 0,02474597 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01036231 0,0247218 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01036231 0,02469769 ! blastocyst formation GO:0001825 18 10 0,000 0,01036231 0,02467361 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01036231 0,02464959 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01036231 0,02462561 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01036231 0,02460168 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01036231 0,02457779 ! response to nicotine GO:0035094 20 10 0,000 0,01036231 0,02455396 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01036231 0,02453016 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01036231 0,02450642 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01139278 0,02691737 ! respiratory burst GO:0045730 17 11 0,000 0,01139278 0,02689136 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01139278 0,0268654 ! neuron fate specification GO:0048665 18 11 0,000 0,01139278 0,0268395 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01139278 0,02681364 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01139278 0,02678783 ! thyroid gland development GO:0030878 26 11 0,000 0,01139278 0,02676207 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01139278 0,02673637 ! synapsis GO:0007129 14 11 0,000 0,01139278 0,02671071 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01139278 0,0266851 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01139278 0,02665954 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01139278 0,02663403 ! response to pain GO:0048265 27 11 0,000 0,01139278 0,02660856 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01139278 0,02658315 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01139278 0,02655778 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01139278 0,02653247 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01139278 0,0265072 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01139278 0,02648198 ! bone resorption GO:0045453 16 11 0,000 0,01139278 0,0264568 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01139278 0,02643168 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01139278 0,0264066 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01139278 0,02638157 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01139278 0,02635659 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01139278 0,02633165 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01139278 0,02630677 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01139278 0,02628192 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01139278 0,02625713 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01139278 0,02623238 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01139278 0,02620768 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01139278 0,02618303 ! UV protection GO:0009650 20 11 0,000 0,01139278 0,02615842 ! adult heart development GO:0007512 16 11 0,000 0,01139278 0,02613386 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01139278 0,02610934 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01139278 0,02608487 ! macroautophagy GO:0016236 19 11 0,000 0,01139278 0,02606045 ! temperature homeostasis GO:0001659 18 11 0,000 0,01139278 0,02603607 ! behavioral fear response GO:0001662 27 11 0,000 0,01139278 0,02601174 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01139278 0,02598745 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01139278 0,02596321 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01139278 0,02593901 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01139278 0,02591486 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01139278 0,02589075 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01139278 0,02586669 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01139278 0,02584267 ! regulation of organ growth GO:0046620 14 11 0,000 0,01139278 0,0258187 ! pigment granule localization GO:0051875 20 11 0,000 0,01139278 0,02579477 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01139278 0,02577089 ! vasoconstriction GO:0042310 20 11 0,000 0,01139278 0,02574705 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01139278 0,02572325 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01139278 0,0256995 ! embryonic axis specification GO:0000578 19 11 0,000 0,01139278 0,02567579 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01139278 0,02565213 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01139278 0,02562851 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01139278 0,02560493 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01139278 0,02558139 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01139278 0,0255579 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01139278 0,02553446 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01139278 0,02551105 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01139278 0,02548769 ! prophase GO:0051324 17 11 0,000 0,01139278 0,02546437 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01139278 0,02544109 ! nucleosome positioning GO:0016584 15 11 0,000 0,01139278 0,02541786 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01139278 0,02539467 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01139278 0,02537152 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01139278 0,02534841 ! apical protein localization GO:0045176 18 11 0,000 0,01139278 0,02532535 ! acid secretion GO:0046717 20 11 0,000 0,01139278 0,02530232 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01139278 0,02527934 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01139278 0,0252564 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01139278 0,02523351 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01139278 0,02521065 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01139278 0,02518783 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01139278 0,02516506 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,01139278 0,02514233 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01139278 0,02511964 ! oocyte development GO:0048599 20 11 0,000 0,01139278 0,02509699 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01139278 0,02507438 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01139278 0,02505181 ! embryonic gut development GO:0048566 19 11 0,000 0,01139278 0,02502928 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01139278 0,02500679 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01139278 0,02498434 ! activation of innate immune response GO:0002218 16 11 0,000 0,01139278 0,02496193 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01139278 0,02493957 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01139278 0,02491724 ! lysogeny GO:0030069 22 11 0,000 0,01139278 0,02489495 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01139278 0,02487271 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01139278 0,0248505 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01139278 0,02482833 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01139278 0,0248062 ! nucleus localization GO:0051647 22 11 0,000 0,01139278 0,02478411 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0124222 0,0269995 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0124222 0,0269755 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0124222 0,02695154 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0124222 0,02692763 ! virus-host interaction GO:0019048 30 12 0,000 0,0124222 0,02690376 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0124222 0,02687993 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0124222 0,02685614 ! protein complex disassembly GO:0043241 28 12 0,000 0,0124222 0,02683239 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0124222 0,02680869 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0124222 0,02678503 ! hippocampus development GO:0021766 29 12 0,000 0,0124222 0,02676141 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0124222 0,02673783 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0124222 0,02671429 ! T cell proliferation GO:0042098 32 12 0,000 0,0124222 0,0266908 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0124222 0,02666734 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0124222 0,02664393 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0124222 0,02662056 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0124222 0,02659723 ! drug transport GO:0015893 16 12 0,000 0,0124222 0,02657394 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0124222 0,02655069 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0124222 0,02652748 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0124222 0,02650431 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0124222 0,02648118 ! focal adhesion formation GO:0048041 37 12 0,000 0,0124222 0,0264581 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0124222 0,02643505 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0124222 0,02641204 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0124222 0,02638908 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0124222 0,02636615 ! lipid digestion GO:0044241 21 12 0,000 0,0124222 0,02634326 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0124222 0,02632041 ! entry into host cell GO:0030260 34 12 0,000 0,0124222 0,02629761 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0124222 0,02627484 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0124222 0,02625211 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0124222 0,02622942 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0124222 0,02620677 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0124222 0,02618416 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0124222 0,02616158 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0124222 0,02613905 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0124222 0,02611655 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0124222 0,0260941 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0124222 0,02607168 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0124222 0,0260493 ! cranial nerve development GO:0021545 23 12 0,000 0,0124222 0,02602696 ! fucose catabolic process GO:0019317 25 12 0,000 0,0124222 0,02600466 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0124222 0,02598239 ! histone acetylation GO:0016573 27 12 0,000 0,0124222 0,02596017 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0124222 0,02593798 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0124222 0,02591583 ! zymogen activation GO:0031638 18 12 0,000 0,0124222 0,02589372 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0124222 0,02587164 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0124222 0,02584961 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0124222 0,02582761 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0124222 0,02580564 ! oocyte differentiation GO:0009994 21 12 0,000 0,0124222 0,02578372 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0124222 0,02576183 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0124222 0,02573998 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0124222 0,02571817 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0124222 0,02569639 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0124222 0,02567465 ! defense response to fungus GO:0050832 15 12 0,000 0,0124222 0,02565295 ! developmental induction GO:0031128 22 12 0,000 0,0124222 0,02563128 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0124222 0,02560965 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0124222 0,02558806 ! response to cold GO:0009409 17 12 0,000 0,0124222 0,0255665 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0124222 0,02554498 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0124222 0,0255235 ! localization within membrane GO:0051668 26 12 0,000 0,0124222 0,02550205 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01345058 0,02759006 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01345058 0,02756692 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01345058 0,02754381 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01345058 0,02752074 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01345058 0,02749771 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01345058 0,02747472 ! peroxisomal transport GO:0043574 28 13 0,000 0,01345058 0,02745177 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01345058 0,02742885 ! cartilage condensation GO:0001502 22 13 0,000 0,01345058 0,02740598 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01345058 0,02738314 ! organelle fusion GO:0048284 36 13 0,000 0,01345058 0,02736034 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01345058 0,02733758 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01345058 0,02731485 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01345058 0,02729217 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01345058 0,02726952 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01345058 0,0272469 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01345058 0,02722433 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01345058 0,02720179 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01345058 0,02717929 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01345058 0,02715683 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01345058 0,02713441 ! methionine metabolic process GO:0006555 31 13 0,000 0,01345058 0,02711202 ! plasma membrane organization GO:0007009 27 13 0,000 0,01345058 0,02708967 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01345058 0,02706735 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01345058 0,02704508 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01345058 0,02702284 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01345058 0,02700063 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01345058 0,02697846 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01345058 0,02695633 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01345058 0,02693424 ! exocrine system development GO:0035272 34 13 0,000 0,01345058 0,02691218 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01345058 0,02689015 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01345058 0,02686817 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01345058 0,02684622 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01345058 0,0268243 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01345058 0,02680242 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01345058 0,02678058 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01345058 0,02675877 ! protein homotetramerization GO:0051289 24 13 0,000 0,01345058 0,026737 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01345058 0,02671526 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01345058 0,02669356 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01345058 0,02667189 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01345058 0,02665026 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01345058 0,02662866 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01345058 0,0266071 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01345058 0,02658557 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01345058 0,02656408 ! histone methylation GO:0016571 29 13 0,000 0,01345058 0,02654262 ! chromatin silencing GO:0006342 29 13 0,000 0,01345058 0,0265212 ! gland morphogenesis GO:0022612 31 13 0,000 0,01345058 0,02649981 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01345058 0,02647846 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01345058 0,02645714 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01345058 0,02643585 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01345058 0,0264146 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01345058 0,02639339 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01345058 0,0263722 ! spleen development GO:0048536 24 13 0,000 0,01345058 0,02635106 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01345058 0,02632994 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01345058 0,02630886 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01345058 0,02628781 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01345058 0,0262668 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01345058 0,02624582 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01345058 0,02622487 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01345058 0,02620396 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01345058 0,02618308 ! insulin secretion GO:0030073 24 13 0,000 0,01345058 0,02616224 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01345058 0,02614142 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01345058 0,02612064 ! acrosome reaction GO:0007340 19 13 0,000 0,01345058 0,02609989 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01345058 0,02607918 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01345058 0,0260585 ! rRNA transcription GO:0009303 28 14 0,000 0,01447792 0,02802659 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01447792 0,0280044 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01447792 0,02798224 ! water transport GO:0006833 21 14 0,000 0,01447792 0,02796012 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01447792 0,02793804 ! non-recombinational repair GO:0000726 29 14 0,000 0,01447792 0,02791598 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01447792 0,02789397 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01447792 0,02787199 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01447792 0,02785004 ! lipid localization GO:0010876 32 14 0,000 0,01447792 0,02782813 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01447792 0,02780625 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01447792 0,02778441 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01447792 0,0277626 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01447792 0,02774083 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01447792 0,02771909 ! arginine metabolic process GO:0006525 21 14 0,000 0,01447792 0,02769738 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01447792 0,02767571 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01447792 0,02765407 ! regulation of heart rate GO:0002027 25 14 0,000 0,01447792 0,02763246 ! fear response GO:0042596 34 14 0,000 0,01447792 0,02761089 ! organic alcohol transport GO:0015850 29 14 0,000 0,01447792 0,02758935 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01447792 0,02756785 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01447792 0,02754638 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01447792 0,02752494 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01447792 0,02750354 ! bone mineralization GO:0030282 18 14 0,000 0,01447792 0,02748217 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01447792 0,02746083 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01447792 0,02743953 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01447792 0,02741826 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01447792 0,02739702 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01447792 0,02737581 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01447792 0,02735464 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01447792 0,0273335 ! ribosome assembly GO:0042255 18 14 0,000 0,01447792 0,0273124 ! cerebellum development GO:0021549 23 14 0,000 0,01447792 0,02729132 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01447792 0,02727028 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01447792 0,02724927 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01447792 0,02722829 ! response to gamma radiation GO:0010332 30 14 0,000 0,01447792 0,02720735 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01447792 0,02718644 ! NADP metabolic process GO:0006739 24 14 0,000 0,01447792 0,02716556 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01447792 0,02714471 ! oxygen transport GO:0015671 22 14 0,000 0,01447792 0,02712389 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01447792 0,02710311 ! male genitalia development GO:0030539 26 14 0,000 0,01447792 0,02708235 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01447792 0,02706163 ! regulation of axon extension GO:0030516 43 14 0,000 0,01447792 0,02704094 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01447792 0,02702028 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01447792 0,02699966 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01447792 0,02697906 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01550421 0,02886951 ! lactation GO:0007595 30 15 0,000 0,01550421 0,02884752 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01550421 0,02882557 ! reproductive cellular process GO:0048610 22 15 0,000 0,01550421 0,02880365 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01550421 0,02878176 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01550421 0,02875991 ! superoxide anion generation GO:0042554 22 15 0,000 0,01550421 0,02873808 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01550421 0,0287163 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01550421 0,02869454 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01550421 0,02867282 ! copper ion transport GO:0006825 22 15 0,000 0,01550421 0,02865113 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01550421 0,02862947 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01550421 0,02860785 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01550421 0,02858626 ! sulfate transport GO:0008272 27 15 0,000 0,01550421 0,0285647 ! response to cAMP GO:0051591 25 15 0,000 0,01550421 0,02854318 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01550421 0,02852168 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01550421 0,02850022 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01550421 0,02847879 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01550421 0,0284574 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01550421 0,02843603 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01550421 0,0284147 ! vesicle coating GO:0006901 38 15 0,000 0,01550421 0,0283934 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01550421 0,02837213 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01550421 0,02835089 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01550421 0,02832969 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01550421 0,02830852 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01550421 0,02828738 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01550421 0,02826627 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01550421 0,02824519 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01550421 0,02822414 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01550421 0,02820312 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01550421 0,02818214 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01550421 0,02816119 ! histone deacetylation GO:0016575 24 15 0,000 0,01550421 0,02814026 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01550421 0,02811937 ! water homeostasis GO:0030104 28 15 0,000 0,01550421 0,02809851 ! cofactor transport GO:0051181 30 15 0,000 0,01550421 0,02807768 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01550421 0,02805689 ! muscle maintenance GO:0046716 26 15 0,000 0,01550421 0,02803612 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01550421 0,02801538 ! intestinal absorption GO:0050892 31 15 0,000 0,01550421 0,02799468 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01550421 0,027974 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01550421 0,02795335 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01550421 0,02793274 ! cell killing GO:0001906 32 15 0,000 0,01550421 0,02791216 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01550421 0,0278916 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01550421 0,02787108 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01550421 0,02785058 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01550421 0,02783012 ! actin filament polymerization GO:0030041 27 15 0,000 0,01550421 0,02780969 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01550421 0,02778928 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01652947 0,0296052 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01652947 0,02958351 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01652947 0,02956186 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01652947 0,02954023 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01652947 0,02951864 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01652947 0,02949708 ! bone remodeling GO:0046849 28 16 0,000 0,01652947 0,02947555 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01652947 0,02945405 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01652947 0,02943258 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01652947 0,02941114 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01652947 0,02938974 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01652947 0,02936836 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01652947 0,02934702 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01652947 0,02932571 ! startle response GO:0001964 28 16 0,000 0,01652947 0,02930442 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01652947 0,02928317 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01652947 0,02926195 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01652947 0,02924077 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01652947 0,02921961 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01652947 0,02919848 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01652947 0,02917738 ! pituitary gland development GO:0021983 30 16 0,000 0,01652947 0,02915632 ! response to osmotic stress GO:0006970 27 16 0,000 0,01652947 0,02913528 ! lysosomal transport GO:0007041 31 16 0,000 0,01652947 0,02911427 ! fructose metabolic process GO:0006000 25 16 0,000 0,01652947 0,0290933 ! L-amino acid transport GO:0015807 33 16 0,000 0,01652947 0,02907235 ! stem cell development GO:0048864 46 16 0,000 0,01652947 0,02905144 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01652947 0,02903055 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01652947 0,0290097 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01652947 0,02898887 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01652947 0,02896808 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01652947 0,02894731 ! axon cargo transport GO:0008088 46 16 0,000 0,01652947 0,02892657 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01652947 0,02890587 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01652947 0,02888519 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01652947 0,02886454 ! neuron recognition GO:0008038 40 16 0,000 0,01652947 0,02884393 ! tissue regeneration GO:0042246 27 16 0,000 0,01652947 0,02882334 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01652947 0,02880278 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01652947 0,02878225 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01652947 0,02876175 ! biomineral formation GO:0031214 22 16 0,000 0,01652947 0,02874128 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01652947 0,02872084 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01652947 0,02870042 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01652947 0,02868004 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01652947 0,02865969 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01652947 0,02863936 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01652947 0,02861906 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01652947 0,02859879 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01652947 0,02857855 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01652947 0,02855834 ! peptide hormone processing GO:0016486 27 16 0,000 0,01652947 0,02853816 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01755369 0,03028507 ! metencephalon development GO:0022037 32 17 0,000 0,01755369 0,0302637 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01755369 0,03024236 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01755369 0,03022104 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01755369 0,03019976 ! signal complex assembly GO:0007172 47 17 0,000 0,01755369 0,03017851 ! filopodium assembly GO:0046847 42 17 0,000 0,01755369 0,03015729 ! endothelial cell migration GO:0043542 31 17 0,000 0,01755369 0,03013609 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01755369 0,03011493 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01755369 0,0300938 ! glial cell development GO:0021782 28 17 0,000 0,01755369 0,03007269 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01755369 0,03005162 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01755369 0,03003058 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01755369 0,03000956 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01755369 0,02998857 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01755369 0,02996762 ! myoblast differentiation GO:0045445 50 17 0,000 0,01755369 0,02994669 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01755369 0,02992579 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01755369 0,02990492 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01755369 0,02988408 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01755369 0,02986327 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01755369 0,02984249 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01755369 0,02982174 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01755369 0,02980102 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01755369 0,02978032 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01755369 0,02975965 ! membrane budding GO:0006900 42 17 0,000 0,01755369 0,02973902 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01755369 0,02971841 ! regulation of protein binding GO:0043393 33 17 0,000 0,01755369 0,02969783 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01755369 0,02967727 ! genitalia development GO:0048806 32 17 0,000 0,01755369 0,02965675 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01755369 0,02963626 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01755369 0,02961579 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01755369 0,02959535 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01755369 0,02957494 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01755369 0,02955456 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01755369 0,0295342 ! steroid catabolic process GO:0006706 34 17 0,000 0,01755369 0,02951388 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01755369 0,02949358 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01755369 0,02947331 ! gas transport GO:0015669 26 17 0,000 0,01755369 0,02945306 ! organic cation transport GO:0015695 32 17 0,000 0,01755369 0,02943285 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01755369 0,02941266 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01755369 0,0293925 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01857687 0,03108445 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01857687 0,03106317 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01857687 0,03104192 ! limbic system development GO:0021761 40 18 0,000 0,01857687 0,0310207 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01857687 0,03099952 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01857687 0,03097836 ! adult walking behavior GO:0007628 36 18 0,000 0,01857687 0,03095722 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01857687 0,03093612 ! heart looping GO:0001947 34 18 0,000 0,01857687 0,03091505 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01857687 0,030894 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01857687 0,03087299 ! centrosome cycle GO:0007098 26 18 0,000 0,01857687 0,030852 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01857687 0,03083104 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01857687 0,03081011 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01857687 0,03078921 ! glycine metabolic process GO:0006544 30 18 0,000 0,01857687 0,03076833 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01857687 0,03074749 ! response to retinoic acid GO:0032526 31 18 0,000 0,01857687 0,03072667 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01857687 0,03070588 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01857687 0,03068512 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01857687 0,03066439 ! DNA integration GO:0015074 32 18 0,000 0,01857687 0,03064368 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01857687 0,030623 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01857687 0,03060235 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01857687 0,03058173 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01857687 0,03056114 ! neural crest cell migration GO:0001755 41 18 0,000 0,01857687 0,03054057 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01857687 0,03052003 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01857687 0,03049952 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01857687 0,03047904 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01857687 0,03045858 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01857687 0,03043816 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01857687 0,03041775 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01857687 0,03039738 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01857687 0,03037703 ! detection of bacterium GO:0016045 22 18 0,000 0,01857687 0,03035672 ! nerve development GO:0021675 34 18 0,000 0,01857687 0,03033642 ! defense response to virus GO:0051607 43 18 0,000 0,01857687 0,03031616 ! microspike assembly GO:0030035 46 18 0,000 0,01857687 0,03029592 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01857687 0,03027571 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01857687 0,03025553 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01959901 0,03189899 ! positive regulation of translation GO:0045727 31 19 0,000 0,01959901 0,03187775 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01959901 0,03185654 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01959901 0,03183536 ! neuron maturation GO:0042551 46 19 0,000 0,01959901 0,03181421 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01959901 0,03179308 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01959901 0,03177199 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01959901 0,03175092 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01959901 0,03172988 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01959901 0,03170886 ! inositol metabolic process GO:0006020 33 19 0,000 0,01959901 0,03168788 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01959901 0,03166692 ! memory GO:0007613 34 19 0,000 0,01959901 0,03164599 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01959901 0,03162509 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01959901 0,03160421 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01959901 0,03158337 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01959901 0,03156255 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01959901 0,03154176 ! cerebral cortex development GO:0021987 40 19 0,000 0,01959901 0,03152099 ! pigmentation during development GO:0048066 42 19 0,000 0,01959901 0,03150025 ! response to vitamin A GO:0033189 32 19 0,000 0,01959901 0,03147954 ! heme metabolic process GO:0042168 40 19 0,000 0,01959901 0,03145886 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01959901 0,0314382 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01959901 0,03141758 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01959901 0,03139697 ! response to fungus GO:0009620 26 19 0,000 0,01959901 0,0313764 ! peptide cross-linking GO:0018149 39 19 0,000 0,01959901 0,03135585 ! protein export from nucleus GO:0006611 40 19 0,000 0,01959901 0,03133533 ! heart process GO:0003015 32 19 0,000 0,01959901 0,03131484 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01959901 0,03129437 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01959901 0,03127393 ! visual learning GO:0008542 38 19 0,000 0,01959901 0,03125352 ! cellular pigmentation GO:0033059 37 19 0,000 0,01959901 0,03123313 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01959901 0,03121277 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01959901 0,03119243 ! vitamin transport GO:0051180 31 19 0,000 0,01959901 0,03117213 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01959901 0,03115184 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01959901 0,03113159 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01959901 0,03111136 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01959901 0,03109116 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01959901 0,03107098 ! cilium assembly GO:0042384 38 19 0,000 0,01959901 0,03105083 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01959901 0,03103071 ! protein secretion GO:0009306 45 20 0,000 0,02062012 0,03262626 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02062012 0,03260515 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02062012 0,03258406 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02062012 0,03256299 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02062012 0,03254196 ! skin development GO:0043588 42 20 0,000 0,02062012 0,03252095 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02062012 0,03249997 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02062012 0,03247901 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02062012 0,03245809 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02062012 0,03243719 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02062012 0,03241631 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02062012 0,03239547 ! response to vitamin GO:0033273 36 20 0,000 0,02062012 0,03237465 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02062012 0,03235385 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02062012 0,03233309 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02062012 0,03231235 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02062012 0,03229164 ! response to alkaloid GO:0043279 38 20 0,000 0,02062012 0,03227095 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02062012 0,03225029 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02062012 0,03222966 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02062012 0,03220905 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02062012 0,03218847 ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02062012 0,03216791 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02062012 0,03214738 ! body fluid secretion GO:0007589 33 20 0,000 0,02062012 0,03212688 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02062012 0,03210641 ! peptide secretion GO:0002790 38 20 0,000 0,02062012 0,03208596 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02062012 0,03206553 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02062012 0,03204513 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02062012 0,03202476 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02062012 0,03200442 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02062012 0,0319841 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02062012 0,0319638 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02062012 0,03194353 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02062012 0,03192329 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02062012 0,03190307 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02062012 0,03188288 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02062012 0,03186271 ! regulation of glucose import GO:0046324 30 20 0,000 0,02062012 0,03184257 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02062012 0,03182246 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02062012 0,03180237 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02062012 0,0317823 ! negative regulation of translation GO:0017148 32 20 0,000 0,02062012 0,03176226 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02062012 0,03174225 ! regulation of cell killing GO:0031341 46 21 0,000 0,02164019 0,03329155 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02164019 0,0332706 ! hormone secretion GO:0046879 39 21 0,000 0,02164019 0,03324968 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02164019 0,03322878 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02164019 0,03320791 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02164019 0,03318706 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02164019 0,03316624 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02164019 0,03314545 ! ovarian follicle development GO:0001541 39 21 0,000 0,02164019 0,03312468 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02164019 0,03310394 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02164019 0,03308322 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02164019 0,03306253 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02164019 0,03304187 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02164019 0,03302123 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02164019 0,03300062 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02164019 0,03298003 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02164019 0,03295947 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02164019 0,03293893 ! sensory perception of pain GO:0019233 33 21 0,000 0,02164019 0,03291842 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02164019 0,03289794 ! diencephalon development GO:0021536 36 21 0,000 0,02164019 0,03287748 ! collagen fibril organization GO:0030199 62 21 0,000 0,02164019 0,03285705 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02164019 0,03283664 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02164019 0,03281626 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02164019 0,0327959 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02164019 0,03277557 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02164019 0,03275526 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02164019 0,03273498 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02164019 0,03271472 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02164019 0,03269449 ! actin filament-based movement GO:0030048 47 21 0,000 0,02164019 0,03267428 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02164019 0,0326541 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02265923 0,03417068 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02265923 0,0341496 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02265923 0,03412854 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02265923 0,03410752 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02265923 0,03408651 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02265923 0,03406554 ! microtubule-based transport GO:0010970 59 22 0,000 0,02265923 0,03404459 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02265923 0,03402366 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02265923 0,03400276 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02265923 0,03398189 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02265923 0,03396104 ! cellular response to starvation GO:0009267 37 22 0,000 0,02265923 0,03394022 ! vacuolar transport GO:0007034 41 22 0,000 0,02265923 0,03391942 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02265923 0,03389865 ! fucose metabolic process GO:0006004 44 22 0,000 0,02265923 0,03387791 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02265923 0,03385719 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02265923 0,03383649 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02265923 0,03381582 ! ureteric bud development GO:0001657 50 22 0,000 0,02265923 0,03379518 ! cell aging GO:0007569 48 22 0,000 0,02265923 0,03377456 ! stem cell differentiation GO:0048863 57 22 0,000 0,02265923 0,03375396 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02265923 0,03373339 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02265923 0,03371285 ! cytolysis GO:0019835 27 22 0,000 0,02265923 0,03369233 ! renal system process GO:0003014 42 22 0,000 0,02265923 0,03367184 ! vasodilation GO:0042311 40 22 0,000 0,02265923 0,03365137 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02265923 0,03363092 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02265923 0,0336105 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02265923 0,03359011 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02265923 0,03356974 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02265923 0,03354939 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02265923 0,03352907 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02265923 0,03350878 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02265923 0,03348851 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02265923 0,03346826 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02265923 0,03344804 ! sarcomere organization GO:0045214 32 22 0,000 0,02265923 0,03342784 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02265923 0,03340766 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02265923 0,03338751 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02265923 0,03336739 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02265923 0,03334729 ! gut development GO:0048565 44 22 0,000 0,02265923 0,03332721 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02265923 0,03330716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02265923 0,03328713 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02265923 0,03326713 ! protein stabilization GO:0050821 41 22 0,000 0,02265923 0,03324715 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02367724 0,03471998 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02367724 0,03469915 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02367724 0,03467835 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02367724 0,03465757 ! gluconeogenesis GO:0006094 38 23 0,000 0,02367724 0,03463682 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02367724 0,03461609 ! viral genome replication GO:0019079 44 23 0,000 0,02367724 0,03459539 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02367724 0,03457471 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02367724 0,03455406 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02367724 0,03453343 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02367724 0,03451282 ! regeneration GO:0031099 42 23 0,000 0,02367724 0,03449224 ! axis specification GO:0009798 43 23 0,000 0,02367724 0,03447169 ! visual behavior GO:0007632 46 23 0,000 0,02367724 0,03445115 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02367724 0,03443065 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02367724 0,03441017 ! response to ethanol GO:0045471 47 23 0,000 0,02367724 0,03438971 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02367724 0,03436927 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02367724 0,03434886 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02367724 0,03432848 ! peroxisome organization GO:0007031 43 23 0,000 0,02367724 0,03430812 ! lysosome organization GO:0007040 47 23 0,000 0,02367724 0,03428778 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02367724 0,03426747 ! vesicle targeting GO:0006903 49 23 0,000 0,02367724 0,03424718 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02367724 0,03422692 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02367724 0,03420668 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02367724 0,03418646 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02367724 0,03416627 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02367724 0,0341461 ! DNA modification GO:0006304 36 23 0,000 0,02367724 0,03412595 ! fatty acid transport GO:0015908 47 23 0,000 0,02367724 0,03410583 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,02367724 0,03408573 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02367724 0,03406566 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02367724 0,03404561 ! hormone transport GO:0009914 41 23 0,000 0,02367724 0,03402558 ! cell-cell recognition GO:0009988 28 23 0,000 0,02367724 0,03400558 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02367724 0,0339856 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02367724 0,03396564 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02367724 0,03394571 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02469421 0,03538297 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02469421 0,03536223 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02469421 0,03534151 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02469421 0,03532082 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02469421 0,03530015 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02469421 0,03527951 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02469421 0,03525889 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02469421 0,03523829 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02469421 0,03521772 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02469421 0,03519717 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02469421 0,03517665 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02469421 0,03515615 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02469421 0,03513568 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02469421 0,03511522 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02469421 0,0350948 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02469421 0,03507439 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02469421 0,03505401 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02469421 0,03503366 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02469421 0,03501332 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02469421 0,03499301 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02469421 0,03497273 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02469421 0,03495247 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02469421 0,03493223 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02469421 0,03491201 ! membrane depolarization GO:0051899 45 24 0,000 0,02469421 0,03489182 ! pallium development GO:0021543 56 24 0,000 0,02469421 0,03487165 ! oogenesis GO:0048477 44 24 0,000 0,02469421 0,03485151 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02469421 0,03483138 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02469421 0,03481128 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02469421 0,03479121 ! platelet activation GO:0030168 41 24 0,000 0,02469421 0,03477116 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02469421 0,03475113 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02469421 0,03473112 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02469421 0,03471114 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02469421 0,03469118 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02469421 0,03467124 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02469421 0,03465132 ! regulation of amine transport GO:0051952 41 24 0,000 0,02469421 0,03463143 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02469421 0,03461156 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02571015 0,03601485 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02571015 0,03599422 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02571015 0,0359736 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02571015 0,03595301 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02571015 0,03593244 ! phototransduction GO:0007602 37 25 0,000 0,02571015 0,0359119 ! keratinization GO:0031424 37 25 0,000 0,02571015 0,03589138 ! vasculogenesis GO:0001570 49 25 0,000 0,02571015 0,03587088 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02571015 0,0358504 ! vacuole organization GO:0007033 49 25 0,000 0,02571015 0,03582995 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02571015 0,03580952 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02571015 0,03578912 ! receptor metabolic process GO:0043112 53 25 0,000 0,02571015 0,03576874 ! chromosome condensation GO:0030261 48 25 0,000 0,02571015 0,03574838 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02571015 0,03572805 ! regulation of behavior GO:0050795 48 25 0,000 0,02571015 0,03570774 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02571015 0,03568745 ! interaction with host GO:0051701 66 25 0,000 0,02571015 0,03566718 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02571015 0,03564694 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02571015 0,03562672 ! immunoglobulin production GO:0002377 62 25 0,000 0,02571015 0,03560652 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02571015 0,03558635 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02571015 0,0355662 ! liver development GO:0001889 55 25 0,000 0,02571015 0,03554607 ! protein tetramerization GO:0051262 57 25 0,000 0,02571015 0,03552597 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02672507 0,03690748 ! myelination GO:0042552 50 26 0,000 0,02672507 0,03688663 ! initiation of viral infection GO:0019059 60 26 0,000 0,02672507 0,03686581 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02672507 0,036845 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02672507 0,03682422 ! molting cycle process GO:0022404 52 26 0,000 0,02672507 0,03680346 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02672507 0,03678273 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02672507 0,03676202 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02672507 0,03674133 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02672507 0,03672066 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02672507 0,03670002 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02672507 0,0366794 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02672507 0,03665881 ! digestive system process GO:0022600 49 26 0,000 0,02672507 0,03663824 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02672507 0,03661769 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02672507 0,03659716 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02672507 0,03657666 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02672507 0,03655618 ! neural crest cell development GO:0014032 59 26 0,000 0,02672507 0,03653573 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02672507 0,03651529 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02672507 0,03649488 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02672507 0,03647449 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02672507 0,03645413 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02672507 0,03643378 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02672507 0,03641346 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02672507 0,03639317 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02672507 0,03637289 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02672507 0,03635264 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02672507 0,03633241 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02672507 0,0363122 ! blastocyst development GO:0001824 50 26 0,000 0,02672507 0,03629202 ! telomere organization GO:0032200 46 26 0,000 0,02672507 0,03627186 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02672507 0,03625172 ! neural tube closure GO:0001843 58 26 0,000 0,02672507 0,0362316 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,02672507 0,0362115 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02672507 0,03619143 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02672507 0,03617138 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02773895 0,03752285 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02773895 0,03750208 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02773895 0,03748134 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02773895 0,03746062 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02773895 0,03743992 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02773895 0,03741925 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02773895 0,0373986 ! iron ion transport GO:0006826 65 27 0,000 0,02773895 0,03737797 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02773895 0,03735737 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02773895 0,03733678 ! tube lumen formation GO:0035148 59 27 0,000 0,02773895 0,03731622 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02773895 0,03729569 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02773895 0,03727517 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02773895 0,03725468 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02773895 0,03723421 ! response to starvation GO:0042594 47 27 0,000 0,02773895 0,03721376 ! response to toxin GO:0009636 49 27 0,000 0,02773895 0,03719334 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02773895 0,03717294 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02773895 0,03715256 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02773895 0,0371322 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02773895 0,03711186 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02773895 0,03709155 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02773895 0,03707126 ! neuron fate commitment GO:0048663 52 28 0,000 0,02875181 0,03840387 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02875181 0,03838288 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02875181 0,03836192 ! vesicle docking GO:0048278 55 28 0,000 0,02875181 0,03834098 ! circadian rhythm GO:0007623 56 28 0,000 0,02875181 0,03832006 ! dendrite development GO:0016358 67 28 0,000 0,02875181 0,03829917 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02875181 0,0382783 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02875181 0,03825745 ! sperm motility GO:0030317 37 28 0,000 0,02875181 0,03823662 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02875181 0,03821582 ! base-excision repair GO:0006284 41 28 0,000 0,02875181 0,03819504 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02875181 0,03817428 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02875181 0,03815354 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02875181 0,03813283 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02875181 0,03811214 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02875181 0,03809147 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02875181 0,03807083 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02875181 0,0380502 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02875181 0,0380296 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02875181 0,03800902 ! lipid oxidation GO:0034440 48 28 0,000 0,02875181 0,03798847 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02875181 0,03796793 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02875181 0,03794742 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02976364 0,03926165 ! translational initiation GO:0006413 66 29 0,000 0,02976364 0,03924046 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02976364 0,0392193 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02976364 0,03919815 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02976364 0,03917703 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02976364 0,03915594 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02976364 0,03913486 ! primary neural tube formation GO:0014020 61 29 0,000 0,02976364 0,03911381 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02976364 0,03909278 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02976364 0,03907178 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02976364 0,03905079 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02976364 0,03902983 ! somitogenesis GO:0001756 52 29 0,000 0,02976364 0,03900889 ! synaptogenesis GO:0007416 46 29 0,000 0,02976364 0,03898798 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02976364 0,03896708 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02976364 0,03894621 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02976364 0,03892536 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,02976364 0,03890453 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03077445 0,04020426 ! phenol metabolic process GO:0018958 56 30 0,000 0,03077445 0,04018278 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03077445 0,04016131 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03077445 0,04013987 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03077445 0,04011845 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03077445 0,04009705 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03077445 0,04007568 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03077445 0,04005433 ! acute-phase response GO:0006953 50 30 0,000 0,03077445 0,040033 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03077445 0,04001169 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03077445 0,03999041 ! myofibril assembly GO:0030239 50 30 0,000 0,03077445 0,03996915 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03077445 0,03994791 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03077445 0,0399267 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03077445 0,03990551 ! cell fate determination GO:0001709 64 30 0,000 0,03077445 0,03988434 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03077445 0,03986319 ! phospholipid transport GO:0015914 65 30 0,000 0,03077445 0,03984206 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03077445 0,03982096 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03077445 0,03979988 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03077445 0,03977882 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03077445 0,03975779 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03077445 0,03973677 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03077445 0,03971578 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03178423 0,04099729 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03178423 0,04097566 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03178423 0,04095404 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03178423 0,04093245 ! cell junction assembly GO:0034329 85 31 0,000 0,03178423 0,04091089 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03178423 0,04088935 ! ovulation cycle process GO:0022602 55 31 0,000 0,03178423 0,04086782 ! peptide transport GO:0015833 60 31 0,000 0,03178423 0,04084633 ! male gonad development GO:0008584 56 31 0,000 0,03178423 0,04082485 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03178423 0,0408034 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03178423 0,04078197 ! detection of light stimulus GO:0009583 44 31 0,000 0,03178423 0,04076056 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03178423 0,04073917 ! natural killer cell activation GO:0030101 50 31 0,000 0,03178423 0,04071781 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03178423 0,04069647 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03178423 0,04067515 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03178423 0,04065386 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03178423 0,04063258 ! eye morphogenesis GO:0048592 65 31 0,000 0,03178423 0,04061133 ! response to heat GO:0009408 54 31 0,000 0,03178423 0,0405901 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03178423 0,0405689 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03279298 0,0418346 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03279298 0,04181277 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03279298 0,04179095 ! spindle organization GO:0007051 50 32 0,000 0,03279298 0,04176917 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03279298 0,0417474 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03279298 0,04172566 ! metanephros development GO:0001656 81 32 0,000 0,03279298 0,04170394 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03279298 0,04168224 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03279298 0,04166056 ! muscle cell development GO:0055001 52 32 0,000 0,03279298 0,04163891 ! mesoderm formation GO:0001707 73 32 0,000 0,03279298 0,04161728 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,03279298 0,04159567 ! ovulation cycle GO:0042698 57 32 0,000 0,03279298 0,04157408 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03279298 0,04155252 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03279298 0,04153098 ! hindbrain development GO:0030902 65 32 0,000 0,03279298 0,04150946 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03279298 0,04148796 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03279298 0,04146649 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03279298 0,04144504 ! gene silencing GO:0016458 71 32 0,000 0,03279298 0,04142361 ! regulation of pH GO:0006885 56 33 0,000 0,03380072 0,0426745 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03380072 0,04265246 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03380072 0,04263044 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03380072 0,04260844 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03380072 0,04258646 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03380072 0,04256451 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03380072 0,04254258 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03380072 0,04252068 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03380072 0,04249879 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03380072 0,04247693 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03380072 0,04245509 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03380072 0,04243328 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03380072 0,04241148 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03380072 0,04238971 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03380072 0,04236796 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03480743 0,04360746 ! glial cell differentiation GO:0010001 67 34 0,000 0,03480743 0,04358511 ! post-embryonic development GO:0009791 76 34 0,000 0,03480743 0,04356278 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03480743 0,04354048 ! cholesterol transport GO:0030301 62 34 0,000 0,03480743 0,0435182 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03480743 0,04349594 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03480743 0,0434737 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03480743 0,04345148 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03480743 0,04342929 ! cell fate specification GO:0001708 56 34 0,000 0,03480743 0,04340712 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03480743 0,04338498 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03480743 0,04336285 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03480743 0,04334075 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03480743 0,04331867 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03581312 0,04454759 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03581312 0,04452492 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03581312 0,04450227 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03581312 0,04447964 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03581312 0,04445704 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03581312 0,04443446 ! membrane docking GO:0022406 69 35 0,000 0,03581312 0,04441191 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03581312 0,04438938 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03581312 0,04436687 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03581312 0,04434438 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03581312 0,04432191 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03581312 0,04429947 ! telencephalon development GO:0021537 81 35 0,000 0,03581312 0,04427705 ! sterol transport GO:0015918 63 35 0,000 0,03581312 0,04425466 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03581312 0,04423228 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03581312 0,04420993 ! placenta development GO:0001890 53 35 0,000 0,03581312 0,04418761 ! vesicle localization GO:0051648 70 35 0,000 0,03581312 0,0441653 ! regulation of muscle development GO:0048634 82 36 0,000 0,0368178 0,04538137 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,0368178 0,04535848 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0368178 0,04533562 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0368178 0,04531278 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0368178 0,04528997 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0368178 0,04526717 ! protein targeting to membrane GO:0006612 75 36 0,000 0,0368178 0,0452444 ! regulation of proteolysis GO:0030162 77 36 0,000 0,0368178 0,04522166 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0368178 0,04519893 ! aerobic respiration GO:0009060 56 36 0,000 0,0368178 0,04517623 ! cytokine production GO:0001816 68 36 0,000 0,0368178 0,04515355 ! embryonic organ development GO:0048568 67 36 0,000 0,0368178 0,0451309 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0368178 0,04510826 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,0368178 0,04508565 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,03782145 0,04629148 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,03782145 0,0462683 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,03782145 0,04624515 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,03782145 0,04622201 ! sister chromatid segregation GO:0000819 65 37 0,000 0,03782145 0,0461989 ! odontogenesis GO:0042476 74 37 0,000 0,03782145 0,04617581 ! actomyosin structure organization GO:0031032 68 37 0,000 0,03782145 0,04615275 ! cell junction organization GO:0034330 96 37 0,000 0,03782145 0,04612971 ! tissue remodeling GO:0048771 78 37 0,000 0,03782145 0,04610669 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,03782145 0,04608369 ! female gonad development GO:0008585 71 37 0,000 0,03782145 0,04606072 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,03782145 0,04603777 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,03782145 0,04601484 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,03782145 0,04599194 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,03782145 0,04596905 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03882409 0,04716422 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03882409 0,04714078 ! meiosis I GO:0007127 74 38 0,000 0,03882409 0,04711736 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03882409 0,04709396 ! organic anion transport GO:0015711 82 38 0,000 0,03882409 0,04707059 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03882409 0,04704724 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03882409 0,04702392 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03882409 0,04700061 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03882409 0,04697734 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03882409 0,04695408 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,03882409 0,04693085 ! regulation of protein stability GO:0031647 77 38 0,000 0,03882409 0,04690764 ! spermatid development GO:0007286 69 38 0,000 0,03882409 0,04688445 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03882409 0,04686128 ! pigment metabolic process GO:0042440 87 38 0,000 0,03882409 0,04683814 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03882409 0,04681503 ! neural tube formation GO:0001841 79 38 0,000 0,03882409 0,04679193 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03982571 0,04797544 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03982571 0,0479518 ! negative regulation of binding GO:0051100 71 39 0,000 0,03982571 0,04792818 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03982571 0,04790458 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03982571 0,047881 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03982571 0,04785745 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03982571 0,04783392 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03982571 0,04781042 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03982571 0,04778693 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03982571 0,04776347 ! glucan metabolic process GO:0044042 64 39 0,000 0,03982571 0,04774004 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04082631 0,04891548 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04082631 0,04889151 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04082631 0,04886755 ! learning GO:0007612 82 40 0,000 0,04082631 0,04884362 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04082631 0,04881971 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04082631 0,04879583 ! lipid homeostasis GO:0055088 75 40 0,000 0,04082631 0,04877197 ! mismatch repair GO:0006298 58 40 0,000 0,04082631 0,04874813 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04082631 0,04872432 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04082631 0,04870052 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04082631 0,04867676 ! RNA export from nucleus GO:0006405 61 41 0,000 0,0418259 0,04984423 ! mRNA catabolic process GO:0006402 79 41 0,000 0,0418259 0,04981993 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,0418259 0,04979565 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,0418259 0,04977139 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,0418259 0,04974716 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,0418259 0,04972295 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,0418259 0,04969877 ! gliogenesis GO:0042063 91 41 0,000 0,0418259 0,04967461 ! feeding behavior GO:0007631 69 41 0,000 0,0418259 0,04965047 ! mesenchymal cell development GO:0014031 94 41 0,000 0,0418259 0,04962636 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,0418259 0,04960227 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,0418259 0,0495782 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,0418259 0,04955416 ! spermatid differentiation GO:0048515 73 41 0,000 0,0418259 0,04953014 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,0418259 0,04950614 ! RNA modification GO:0009451 64 41 0,000 0,0418259 0,04948217 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04282447 0,05063901 ! ear morphogenesis GO:0042471 64 42 0,000 0,04282447 0,05061451 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04282447 0,05059003 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,04282447 0,05056558 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04282447 0,05054116 ! T cell differentiation GO:0030217 93 42 0,000 0,04282447 0,05051675 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04282447 0,05049237 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04282447 0,05046801 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04282447 0,05044368 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04282447 0,05041937 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04282447 0,05039508 ! cytokinesis GO:0000910 84 42 0,000 0,04282447 0,05037082 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04282447 0,05034658 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04382204 0,05149458 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04382204 0,05146983 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04382204 0,05144509 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04382204 0,05142038 ! regulation of tube size GO:0035150 76 43 0,000 0,04382204 0,0513957 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04382204 0,05137104 ! glucose transport GO:0015758 66 43 0,000 0,04382204 0,0513464 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,04382204 0,05132178 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04382204 0,05129719 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04382204 0,05127262 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04382204 0,05124808 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04382204 0,05122356 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04382204 0,05119906 ! segmentation GO:0035282 78 43 0,000 0,04382204 0,05117459 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04382204 0,05115014 ! neuron migration GO:0001764 85 43 0,000 0,04382204 0,05112571 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04382204 0,05110131 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,04481859 0,05223846 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,04481859 0,05221355 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,04481859 0,05218866 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,04481859 0,0521638 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,04481859 0,05213896 ! hexose transport GO:0008645 68 44 0,000 0,04481859 0,05211414 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,04481859 0,05208935 ! striated muscle contraction GO:0006941 85 44 0,000 0,04481859 0,05206458 ! phagocytosis GO:0006909 105 44 0,000 0,04481859 0,05203984 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,04481859 0,05201511 ! double-strand break repair GO:0006302 85 44 0,000 0,04481859 0,05199042 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,04581413 0,05312004 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,04581413 0,05309484 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,04581413 0,05306966 ! keratinocyte differentiation GO:0030216 81 45 0,000 0,04581413 0,05304451 ! biopolymer methylation GO:0043414 91 45 0,000 0,04581413 0,05301939 ! B cell differentiation GO:0030183 124 45 0,000 0,04581413 0,05299428 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,04581413 0,0529692 ! female gamete generation GO:0007292 71 45 0,000 0,04581413 0,05294414 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,04581413 0,05291911 ! polyol metabolic process GO:0019751 77 45 0,000 0,04581413 0,0528941 ! developmental growth GO:0048589 88 45 0,000 0,04581413 0,05286912 ! maintenance of location in cell GO:0051651 101 45 0,000 0,04581413 0,05284416 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,04680866 0,05396582 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,04680866 0,05394036 ! glycolysis GO:0006096 71 46 0,000 0,04680866 0,05391493 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,04680866 0,05388952 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,04680866 0,05386414 ! leukocyte migration GO:0050900 75 46 0,000 0,04680866 0,05383878 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,04680866 0,05381344 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,04680866 0,05378813 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,04680866 0,05376284 ! pigmentation GO:0043473 103 46 0,000 0,04680866 0,05373758 ! cell growth GO:0016049 90 46 0,000 0,04680866 0,05371234 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,04680866 0,05368712 ! neural tube development GO:0021915 91 47 0,000 0,04780219 0,05480091 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04780219 0,05477521 ! response to insulin stimulus GO:0032868 98 47 0,000 0,04780219 0,05474953 ! positive regulation of defense response GO:0031349 88 48 0,000 0,0487947 0,0558601 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,0487947 0,05583394 ! mitochondrial transport GO:0006839 94 48 0,000 0,0487947 0,0558078 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,0487947 0,05578168 ! cellular component disassembly GO:0022411 89 48 0,000 0,0487947 0,05575559 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,0487947 0,05572953 ! endosome transport GO:0016197 127 48 0,000 0,0487947 0,05570348 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,0487947 0,05567747 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,0487947 0,05565147 ! male sex differentiation GO:0046661 93 48 0,000 0,0487947 0,0556255 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,0487947 0,05559956 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,0487947 0,05557364 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,0487947 0,05554774 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,0487947 0,05552187 ! methylation GO:0032259 97 48 0,000 0,0487947 0,05549602 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,04978621 0,05659735 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,04978621 0,05657103 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,04978621 0,05654473 ! JNK cascade GO:0007254 106 49 0,000 0,04978621 0,05651845 ! protein homooligomerization GO:0051260 84 49 0,000 0,04978621 0,0564922 ! regulation of action potential GO:0001508 102 50 0,000 0,05077671 0,05758937 ! regulation of ion transport GO:0043269 86 50 0,000 0,05077671 0,05756265 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05077671 0,05753595 ! endocrine system development GO:0035270 109 50 0,000 0,05077671 0,05750928 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05077671 0,05748263 ! activation of caspase activity GO:0006919 95 50 0,000 0,05077671 0,057456 ! regulation of ossification GO:0030278 123 50 0,000 0,05077671 0,0574294 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05077671 0,05740283 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05077671 0,05737628 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05077671 0,05734975 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,05077671 0,05732325 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05077671 0,05729677 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05176621 0,05838636 ! viral infectious cycle GO:0019058 104 51 0,000 0,05176621 0,05835942 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05176621 0,0583325 ! peptide metabolic process GO:0006518 80 51 0,000 0,05176621 0,0583056 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05176621 0,05827873 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05176621 0,05825189 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05176621 0,05822507 ! positive regulation of binding GO:0051099 88 52 0,000 0,05275471 0,05930959 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05275471 0,05928231 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05275471 0,05925506 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,05275471 0,05922783 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,05275471 0,05920062 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05275471 0,05917344 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05275471 0,05914628 ! excretion GO:0007588 87 52 0,000 0,05275471 0,05911915 ! histone modification GO:0016570 104 52 0,000 0,05275471 0,05909204 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05275471 0,05906496 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05275471 0,05903791 ! amino acid activation GO:0043038 98 52 0,000 0,05275471 0,05901087 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 0,000 0,0537422 0,06008796 ! inner ear development GO:0048839 89 53 0,000 0,0537422 0,06006047 ! chromatin remodeling GO:0006338 122 53 0,000 0,0537422 0,06003301 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,0537422 0,06000557 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0537422 0,05997816 ! vesicle organization GO:0016050 127 53 0,000 0,0537422 0,05995077 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,0537422 0,05992341 ! cartilage development GO:0051216 99 53 0,000 0,0537422 0,05989607 ! synapse organization GO:0050808 102 53 0,000 0,0537422 0,05986876 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,05472869 0,06093992 ! regulation of translational initiation GO:0006446 87 54 0,000 0,05472869 0,06091216 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,05472869 0,06088442 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,05472869 0,06085671 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,05472869 0,06082902 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,05472869 0,06080136 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,05472869 0,06077372 ! membrane fusion GO:0006944 122 54 0,000 0,05472869 0,06074611 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,05472869 0,06071852 ! covalent chromatin modification GO:0016569 115 54 0,000 0,05472869 0,06069096 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,05472869 0,06066342 ! regulation of cell shape GO:0008360 142 54 0,000 0,05472869 0,06063591 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,05472869 0,06060843 ! RNA catabolic process GO:0006401 103 55 0,000 0,05571418 0,06167184 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,05571418 0,0616439 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,05571418 0,061616 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,05571418 0,06158812 ! cell recognition GO:0008037 98 55 0,000 0,05571418 0,06156026 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,05571418 0,06153243 ! cell maturation GO:0048469 107 55 0,000 0,05571418 0,06150463 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,05571418 0,06147685 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,05571418 0,06144909 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,05669867 0,0625067 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,05669867 0,06247851 ! glucose catabolic process GO:0006007 88 56 0,000 0,05669867 0,06245034 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,05669867 0,06242219 ! regulation of DNA replication GO:0006275 105 56 0,000 0,05669867 0,06239408 ! RNA elongation GO:0006354 90 56 0,000 0,05669867 0,06236598 ! chloride transport GO:0006821 102 57 0,000 0,05768216 0,06341923 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,05768216 0,0633907 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,05768216 0,06336219 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,05768216 0,06333372 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,05768216 0,06330526 ! heart morphogenesis GO:0003007 105 57 0,000 0,05768216 0,06327684 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,05768216 0,06324844 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,05768216 0,06322006 ! regulation of actin filament length GO:0030832 118 58 0,000 0,05866466 0,06426805 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,05866466 0,06423924 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,05866466 0,06421046 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,05866466 0,06418171 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,05866466 0,06415298 ! aging GO:0007568 112 58 0,000 0,05866466 0,06412427 ! gastrulation GO:0007369 122 58 0,000 0,05866466 0,0640956 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,05866466 0,06406694 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,05866466 0,06403832 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,05866466 0,06400972 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,05866466 0,06398114 ! maintenance of location GO:0051235 124 58 0,000 0,05866466 0,06395259 ! nuclear export GO:0051168 110 59 0,000 0,05964615 0,06499355 ! establishment of organelle localization GO:0051656 122 59 0,000 0,05964615 0,06496458 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,06062665 0,06600308 ! lipid modification GO:0030258 112 60 0,000 0,06062665 0,06597368 ! DNA catabolic process GO:0006308 94 60 0,000 0,06062665 0,06594431 ! regulation of endocytosis GO:0030100 104 60 0,000 0,06062665 0,06591496 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,06062665 0,06588564 ! adult behavior GO:0030534 104 60 0,000 0,06062665 0,06585634 ! kidney development GO:0001822 133 60 0,000 0,06062665 0,06582707 ! positive regulation of secretion GO:0051047 110 61 0,000 0,06160616 0,06686088 ! regulation of cellular component size GO:0032535 125 61 0,000 0,06160616 0,06683119 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,06160616 0,06680153 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,06160616 0,06677189 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,06160616 0,06674228 ! regulation of heart contraction GO:0008016 123 61 0,000 0,06160616 0,0667127 ! camera-type eye development GO:0043010 126 61 0,000 0,06160616 0,06668314 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,06160616 0,06665361 ! viral reproductive process GO:0022415 132 62 0,000 0,06258467 0,06768232 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,06258467 0,06765237 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,06258467 0,06762245 ! tRNA processing GO:0008033 102 62 0,000 0,06258467 0,06759255 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,06258467 0,06756269 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,06356219 0,06858765 ! regulation of mitosis GO:0007088 112 63 0,000 0,06356219 0,06855737 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,06356219 0,06852711 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,06356219 0,06849688 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,06356219 0,06846668 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,06453872 0,06948792 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,06453872 0,06945731 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,06453872 0,06942673 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,06453872 0,06939617 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,06551426 0,07041414 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,06551426 0,07038317 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,06551426 0,07035223 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,06551426 0,07032132 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,06551426 0,07029044 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,06551426 0,07025958 ! ear development GO:0043583 114 66 0,000 0,06648881 0,07127343 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,06648881 0,07124217 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,06648881 0,07121094 ! gonad development GO:0008406 115 66 0,000 0,06648881 0,07117973 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,06648881 0,07114856 ! activation of MAPK activity GO:0000187 124 67 0,000 0,06746237 0,07215874 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,06746237 0,07212716 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,06746237 0,07209561 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,06746237 0,07206408 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,06746237 0,07203259 ! secondary metabolic process GO:0019748 125 67 0,000 0,06746237 0,07200112 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,06746237 0,07196968 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,06843494 0,07297536 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,06843494 0,07294352 ! hexose catabolic process GO:0019320 113 68 0,000 0,06843494 0,07291171 ! extracellular matrix organization GO:0030198 146 68 0,000 0,06843494 0,07287993 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,06843494 0,07284817 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,06843494 0,07281644 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,06843494 0,07278474 ! viral reproduction GO:0016032 142 68 0,000 0,06843494 0,07275307 ! regulation of lipase activity GO:0060191 137 68 0,000 0,06843494 0,07272142 ! adaptive immune response GO:0002250 126 68 0,000 0,06843494 0,0726898 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,06843494 0,07265821 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,06940652 0,07365774 ! lung development GO:0030324 165 69 0,000 0,06940652 0,07362576 ! urogenital system development GO:0001655 149 69 0,000 0,06940652 0,07359381 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,06940652 0,07356188 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,06940652 0,07352998 ! developmental maturation GO:0021700 128 69 0,000 0,06940652 0,0734981 ! single fertilization GO:0007338 83 69 0,000 0,06940652 0,07346626 ! cell redox homeostasis GO:0045454 114 70 0,000 0,07037712 0,07446137 ! germ cell development GO:0007281 133 70 0,000 0,07037712 0,07442913 ! activation of immune response GO:0002253 120 70 0,000 0,07037712 0,07439693 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,07037712 0,07436475 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,07134673 0,07535671 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,07134673 0,07532414 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,07134673 0,0752916 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,07134673 0,07525909 ! appendage morphogenesis GO:0035107 150 72 0,000 0,07231536 0,07624792 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,07231536 0,07621502 ! respiratory tube development GO:0030323 171 72 0,000 0,07231536 0,07618216 ! actin filament organization GO:0007015 167 72 0,000 0,07231536 0,07614932 ! B cell activation GO:0042113 179 72 0,000 0,07231536 0,07611651 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,07231536 0,07608373 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,07231536 0,07605098 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,07231536 0,07601825 ! appendage development GO:0048736 151 73 0,000 0,07328301 0,07700231 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,07328301 0,07696921 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,07328301 0,07693613 ! regulation of immune effector process GO:0002697 156 73 0,000 0,07328301 0,07690308 ! acute inflammatory response GO:0002526 118 74 0,000 0,07424967 0,07788404 ! amino acid transport GO:0006865 148 74 0,000 0,07424967 0,07785062 ! regulation of caspase activity GO:0043281 136 74 0,000 0,07424967 0,07781722 ! respiratory system development GO:0060541 175 74 0,000 0,07424967 0,07778385 ! organelle localization GO:0051640 155 74 0,000 0,07424967 0,07775051 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,07521535 0,07872798 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,07521535 0,07869426 ! reproductive structure development GO:0048608 131 75 0,000 0,07521535 0,07866058 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,07521535 0,07862692 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,07521535 0,07859329 ! eye development GO:0001654 155 75 0,000 0,07521535 0,07855969 ! axon guidance GO:0007411 162 75 0,000 0,07521535 0,07852611 ! rhythmic process GO:0048511 142 75 0,000 0,07521535 0,07849257 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,07618005 0,07946536 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,07618005 0,07943144 ! learning or memory GO:0007611 161 76 0,000 0,07618005 0,07939756 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,07618005 0,0793637 ! regulation of blood pressure GO:0008217 134 76 0,000 0,07618005 0,07932987 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,07618005 0,07929607 ! amine catabolic process GO:0009310 136 77 0,000 0,07714378 0,08026501 ! neurotransmitter transport GO:0006836 142 77 0,000 0,07714378 0,08023084 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,07714378 0,0801967 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,07714378 0,08016259 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,07714378 0,08012851 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,07714378 0,08009445 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,07714378 0,08006043 ! regulation of catabolic process GO:0009894 173 77 0,000 0,07714378 0,08002643 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,07810652 0,08099076 ! antigen processing and presentation GO:0019882 117 78 0,000 0,07810652 0,0809564 ! fertilization GO:0009566 99 78 0,000 0,07810652 0,08092207 ! blood coagulation GO:0007596 151 79 0,000 0,07906829 0,08188378 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,07906829 0,08184908 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,07906829 0,08181441 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,07906829 0,08177978 ! protein oligomerization GO:0051259 149 79 0,000 0,07906829 0,08174517 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,07906829 0,08171059 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,08002908 0,08266852 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,08002908 0,08263358 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,08002908 0,08259867 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,08002908 0,08256379 ! meiosis GO:0007126 143 81 0,000 0,0809889 0,08351873 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,0809889 0,08348349 ! response to hypoxia GO:0001666 178 81 0,000 0,0809889 0,08344828 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,0809889 0,0834131 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,08194774 0,08436508 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,08194774 0,08432954 ! protein import into nucleus GO:0006606 174 82 0,000 0,08194774 0,08429403 ! meiotic cell cycle GO:0051321 144 82 0,000 0,08194774 0,08425856 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,08290561 0,08520757 ! exocytosis GO:0006887 153 83 0,000 0,08290561 0,08517174 ! response to drug GO:0042493 149 83 0,000 0,08290561 0,08513594 ! response to oxygen levels GO:0070482 183 83 0,000 0,08290561 0,08510017 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,08290561 0,08506443 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,08290561 0,08502872 ! nuclear import GO:0051170 177 83 0,000 0,08290561 0,08499303 ! inorganic anion transport GO:0015698 156 83 0,000 0,08290561 0,08495738 ! T cell activation GO:0042110 189 84 0,000 0,0838625 0,08590193 ! response to nutrient GO:0007584 135 84 0,000 0,0838625 0,08586593 ! digestion GO:0007586 130 84 0,000 0,0838625 0,08582995 ! hemostasis GO:0007599 165 85 0,000 0,08481843 0,08677195 ! negative regulation of transport GO:0051051 164 85 0,000 0,08481843 0,08673563 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,08481843 0,08669934 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,08481843 0,08666308 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,08481843 0,08662685 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,08481843 0,08659065 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,08481843 0,08655448 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,08577338 0,08749243 ! regulation of lyase activity GO:0051339 169 86 0,000 0,08577338 0,08745592 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,08672737 0,08839172 ! mitochondrion organization GO:0007005 159 87 0,000 0,08672737 0,08835486 ! alcohol catabolic process GO:0046164 142 87 0,000 0,08672737 0,08831803 ! regulation of protein transport GO:0051223 165 87 0,000 0,08672737 0,08828123 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,08768038 0,08921415 ! sensory perception of smell GO:0007608 117 88 0,000 0,08768038 0,08917701 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,08768038 0,0891399 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,08863243 0,09007031 ! regulation of DNA binding GO:0051101 167 89 0,000 0,08863243 0,09003286 ! tube morphogenesis GO:0035239 194 89 0,000 0,08863243 0,08999544 ! cellular defense response GO:0006968 123 89 0,000 0,08863243 0,08995805 ! protein localization in nucleus GO:0034504 192 89 0,000 0,08863243 0,08992069 ! regulation of neurological system process GO:0031644 175 89 0,000 0,08863243 0,08988337 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,08958351 0,09081018 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,09053363 0,09173524 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,09053363 0,0916972 ! gland development GO:0048732 220 91 0,000 0,09053363 0,0916592 ! defense response to bacterium GO:0042742 112 91 0,000 0,09053363 0,09162123 ! bone development GO:0060348 206 92 0,000 0,09148278 0,09254345 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,09148278 0,09250515 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,09243097 0,09342526 ! amine transport GO:0015837 181 93 0,000 0,09243097 0,09338662 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,09243097 0,09334802 ! vitamin metabolic process GO:0006766 153 93 0,000 0,09243097 0,09330944 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,09337819 0,09422673 ! female pregnancy GO:0007565 166 94 0,000 0,09337819 0,09418783 ! sterol metabolic process GO:0016125 166 94 0,000 0,09337819 0,09414896 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,09337819 0,09411012 ! regulation of membrane potential GO:0042391 179 94 0,000 0,09337819 0,09407131 ! regulation of defense response GO:0031347 171 95 0,000 0,09432446 0,09498543 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,09432446 0,09494629 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,09432446 0,09490718 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,09432446 0,09486811 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,09432446 0,09482907 ! sex differentiation GO:0007548 171 96 0,000 0,09526976 0,09574003 ! regulation of T cell activation GO:0050863 175 96 0,000 0,09526976 0,09570066 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,0962141 0,09660955 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,0962141 0,09656986 ! transcription initiation GO:0006352 171 97 0,000 0,0962141 0,0965302 ! regulation of protein localization GO:0032880 188 97 0,000 0,0962141 0,09649058 ! leukocyte differentiation GO:0002521 232 98 0,000 0,09715748 0,09739669 ! forebrain development GO:0030900 210 98 0,000 0,09715748 0,09735674 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,09715748 0,09731682 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,09904137 0,09916314 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,09904137 0,09912252 ! positive regulation of immune response GO:0050778 175 100 0,000 0,09904137 0,09908193 ! hormone metabolic process GO:0042445 171 100 0,000 0,09904137 0,09904137