pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/90861-10-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 5,881E-11 1,353E-07 ! anterior/posterior pattern formation GO:0009952 124 85 5,000 1,386E-09 1,594E-06 ! embryonic organ morphogenesis GO:0048562 23 19 3,000 1,044E-08 8,006E-06 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 1,609E-08 9,254E-06 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,011E-07 4,652E-05 ! interphase GO:0051325 159 88 4,000 1,136E-07 4,353E-05 ! embryonic organ development GO:0048568 45 34 3,000 1,232E-07 4,049E-05 ! cartilage development GO:0051216 70 49 3,000 5,553E-07 1,597E-04 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 1,802E-05 4,604E-03 ! anagen GO:0042640 6 5 1,000 1,802E-05 4,144E-03 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 1,802E-05 3,767E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 1,802E-05 3,453E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 1,802E-05 3,188E-03 GO:0007439|ectodermal gut development, ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 2,172E-05 3,569E-03 ! embryonic skeletal system development GO:0048706 56 42 2,000 2,52E-05 3,863E-03 ! hair follicle maturation GO:0048820 7 6 1,000 2,7E-05 3,882E-03 ! regulation of myoblast differentiation GO:0045661 8 6 1,000 2,7E-05 3,653E-03 ! regulation of epidermal cell differentiation GO:0045604 7 6 1,000 2,7E-05 3,45E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 2,706E-05 3,276E-03 ! response to UV GO:0009411 75 46 2,000 3,32E-05 3,818E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,777E-05 4,137E-03 ! negative regulation of muscle cell differentiation GO:0051148 9 7 1,000 3,777E-05 3,949E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 3,777E-05 3,777E-03 ! positive regulation of epidermis development GO:0045684 11 7 1,000 3,777E-05 3,62E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 5,032E-05 4,63E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 5,032E-05 4,452E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 5,032E-05 4,287E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,032E-05 4,134E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 5,032E-05 3,991E-03 ! icosanoid secretion GO:0032309 12 8 1,000 5,032E-05 3,858E-03 GO:0050482|arachidonic acid secretion, ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 6,336E-05 4,701E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 6,464E-05 4,646E-03 ! endoderm development GO:0007492 12 9 1,000 6,464E-05 4,506E-03 ! V(D)J recombination GO:0033151 12 9 1,000 6,464E-05 4,373E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 6,464E-05 4,248E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 6,464E-05 4,13E-03 ! DNA ligation GO:0006266 14 9 1,000 6,464E-05 4,018E-03 ! acid secretion GO:0046717 14 9 1,000 6,464E-05 3,913E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 6,675E-05 3,937E-03 ! negative regulation of transferase activity GO:0051348 105 61 2,000 7,765E-05 4,465E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 7,765E-05 4,356E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 8,074E-05 4,421E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 8,074E-05 4,319E-03 ! hair follicle morphogenesis GO:0031069 17 10 1,000 8,074E-05 4,22E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 8,074E-05 4,127E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 8,153E-05 4,076E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 9,39E-05 4,595E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 9,39E-05 4,5E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 9,86E-05 4,628E-03 ! digestive tract morphogenesis GO:0048546 15 11 1,000 9,86E-05 4,535E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! lysogeny GO:0030069 18 11 1,000 9,86E-05 4,447E-03 GO:0019047|provirus integration, ! positive regulation of ligase activity GO:0051351 99 69 2,000 1,122E-04 4,964E-03 ! non-recombinational repair GO:0000726 19 12 1,000 1,182E-04 5,13E-03 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of cell growth GO:0030307 16 12 1,000 1,182E-04 5,035E-03 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 1,182E-04 4,944E-03 ! regulation of epidermis development GO:0045682 17 12 1,000 1,182E-04 4,855E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 1,222E-04 4,931E-03 ! regulation of ligase activity GO:0051340 114 75 2,000 1,439E-04 5,705E-03 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 1,627E-04 6,343E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,627E-04 6,238E-03 ! epidermis morphogenesis GO:0048730 29 14 1,000 1,627E-04 6,135E-03 ! negative regulation of caspase activity GO:0043154 20 14 1,000 1,627E-04 6,037E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,627E-04 5,941E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 1,627E-04 5,848E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 1,743E-04 6,166E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of protein ubiquitination GO:0031396 19 15 1,000 1,876E-04 6,538E-03 ! positive regulation of cell size GO:0045793 20 15 1,000 1,876E-04 6,44E-03 ! skin development GO:0043588 25 15 1,000 1,876E-04 6,345E-03 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 1,876E-04 6,253E-03 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 1,876E-04 6,164E-03 ! DNA integration GO:0015074 22 15 1,000 1,876E-04 6,077E-03 ! negative regulation of translation GO:0017148 22 16 1,000 2,142E-04 6,843E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,142E-04 6,749E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 2,142E-04 6,658E-03 ! G1 phase GO:0051318 27 16 1,000 2,142E-04 6,569E-03 ! regulation of neurogenesis GO:0050767 153 89 2,000 2,389E-04 7,231E-03 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 2,426E-04 7,246E-03 ! long-chain fatty acid transport GO:0015909 24 17 1,000 2,426E-04 7,153E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 2,727E-04 7,939E-03 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 2,727E-04 7,839E-03 ! gut development GO:0048565 26 18 1,000 2,727E-04 7,743E-03 ! response to light stimulus GO:0009416 153 96 2,000 2,987E-04 8,378E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,045E-04 8,438E-03 ! smooth muscle contraction GO:0006939 36 19 1,000 3,045E-04 8,337E-03 ! hindlimb morphogenesis GO:0035137 32 20 1,000 3,38E-04 9,147E-03 ! determination of left/right symmetry GO:0007368 23 20 1,000 3,38E-04 9,041E-03 ! positive regulation of B cell activation GO:0050871 31 20 1,000 3,38E-04 8,937E-03 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 3,733E-04 9,757E-03 GO:0016444|somatic cell DNA recombination, ! determination of bilateral symmetry GO:0009855 25 21 1,000 3,733E-04 9,648E-03 GO:0009799|determination of symmetry, ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,733E-04 9,54E-03 ! regulation of vasoconstriction GO:0019229 31 21 1,000 3,733E-04 9,435E-03 ! fatty acid transport GO:0015908 30 21 1,000 3,733E-04 9,333E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 3,733E-04 9,233E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 4,103E-04 0,01003938 ! molting cycle process GO:0022404 40 22 1,000 4,103E-04 9,934E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 4,103E-04 9,83E-03 GO:0010810|regulation of cell-substrate adhesion, ! neuron fate commitment GO:0048663 32 23 1,000 4,49E-04 0,01064652 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 4,49E-04 0,01053788 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 4,49E-04 0,01043144 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,49E-04 0,01032712 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 4,49E-04 0,01022487 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 4,49E-04 0,01012463 ! initiation of viral infection GO:0019059 42 24 1,000 4,894E-04 0,01092865 ! fat cell differentiation GO:0045444 37 24 1,000 4,894E-04 0,01082357 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 5,315E-04 0,01164294 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 50 26 1,000 5,753E-04 0,01248372 ! response to ionizing radiation GO:0010212 47 27 1,000 6,208E-04 0,01334523 ! regulation of B cell activation GO:0050864 42 28 1,000 6,68E-04 0,01422678 ! spindle organization GO:0007051 37 30 1,000 7,675E-04 0,01619472 ! positive regulation of neurogenesis GO:0050769 45 30 1,000 7,675E-04 0,0160475 ! glial cell differentiation GO:0010001 55 31 1,000 8,197E-04 0,01698544 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 8,197E-04 0,01683378 ! cell fate specification GO:0001708 37 31 1,000 8,197E-04 0,01668481 ! regulation of muscle development GO:0048634 48 32 1,000 8,736E-04 0,01762624 ! meiosis I GO:0007127 52 32 1,000 8,736E-04 0,01747297 ! RNA export from nucleus GO:0006405 44 33 1,000 9,292E-04 0,01842447 ! positive regulation of cell development GO:0010720 54 33 1,000 9,292E-04 0,018267 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 9,292E-04 0,01811219 ! Notch signaling pathway GO:0007219 56 35 1,000 1,045E-03 0,02020512 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,045E-03 0,02003674 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,045E-03 0,01987115 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! gliogenesis GO:0042063 71 38 1,000 1,232E-03 0,02322713 ! monocarboxylic acid transport GO:0015718 62 38 1,000 1,232E-03 0,02303829 ! mesenchymal cell development GO:0014031 64 38 1,000 1,232E-03 0,0228525 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 1,298E-03 0,02387507 ! developmental growth GO:0048589 62 39 1,000 1,298E-03 0,02368558 ! response to calcium ion GO:0051592 58 40 1,000 1,365E-03 0,02471517 ! double-strand break repair GO:0006302 67 40 1,000 1,365E-03 0,02452208 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,365E-03 0,02433199 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 1,504E-03 0,02660756 ! response to insulin stimulus GO:0032868 63 43 1,000 1,576E-03 0,0276693 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 1,65E-03 0,02874321 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,725E-03 0,02982896 ! vascular process in circulatory system GO:0003018 69 45 1,000 1,725E-03 0,02960635 ! viral infectious cycle GO:0019058 71 47 1,000 1,88E-03 0,0320346 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 1,88E-03 0,03179905 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 75 48 1,000 1,96E-03 0,03291186 ! nuclear export GO:0051168 69 48 1,000 1,96E-03 0,03267337 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 2,042E-03 0,03379037 ! positive regulation of growth GO:0045927 67 50 1,000 2,125E-03 0,03491765 ! skeletal system morphogenesis GO:0048705 78 53 1,000 2,385E-03 0,03890243 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 2,659E-03 0,04306148 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,753E-03 0,04427822 ! developmental maturation GO:0021700 75 57 1,000 2,753E-03 0,04397073 ! viral reproductive process GO:0022415 87 58 1,000 2,849E-03 0,04518922 ! lung development GO:0030324 94 59 1,000 2,946E-03 0,04641559 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 3,045E-03 0,04764962 GO:0035113|embryonic appendage morphogenesis, ! meiosis GO:0007126 96 61 1,000 3,146E-03 0,04889108 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 1,000 3,248E-03 0,05013977 ! respiratory tube development GO:0030323 99 62 1,000 3,248E-03 0,0498055 ! meiotic cell cycle GO:0051321 97 62 1,000 3,248E-03 0,04947567 ! viral reproduction GO:0016032 92 63 1,000 3,352E-03 0,05071922 ! negative regulation of cell size GO:0045792 108 64 1,000 3,457E-03 0,05196966 ! appendage morphogenesis GO:0035107 93 64 1,000 3,457E-03 0,05163219 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 3,457E-03 0,05129908 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 3,457E-03 0,05097024 ! respiratory system development GO:0060541 100 64 1,000 3,457E-03 0,05064559 ! regulation of caspase activity GO:0043281 97 65 1,000 3,564E-03 0,05187927 ! appendage development GO:0048736 94 65 1,000 3,564E-03 0,05155299 GO:0060173|limb development, ! regulation of actin filament-based process GO:0032970 99 66 1,000 3,672E-03 0,05278759 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 3,672E-03 0,05245972 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 3,782E-03 0,05369517 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 3,782E-03 0,05336575 ! regulation of neuron differentiation GO:0045664 107 67 1,000 3,782E-03 0,05304035 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 3,893E-03 0,05427105 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 3,893E-03 0,05394411 ! response to metal ion GO:0010038 103 70 1,000 4,121E-03 0,05675094 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 4,121E-03 0,05641313 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 4,237E-03 0,05765661 ! regulation of peptidase activity GO:0052547 106 72 1,000 4,354E-03 0,05890584 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 4,354E-03 0,05856136 GO:0045937|positive regulation of phosphate metabolic process, ! tube morphogenesis GO:0035239 118 73 1,000 4,473E-03 0,05981091 ! mitochondrion organization GO:0007005 104 73 1,000 4,473E-03 0,05946518 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 4,593E-03 0,06071499 ! response to inorganic substance GO:0010035 115 75 1,000 4,715E-03 0,06197016 ! negative regulation of growth GO:0045926 123 75 1,000 4,715E-03 0,06161806 ! response to unfolded protein GO:0006986 99 76 1,000 4,839E-03 0,06287333 ! positive regulation of protein modification process GO:0031401 107 78 1,000 5,09E-03 0,06576647 ! regulation of GTPase activity GO:0043087 129 80 1,000 5,347E-03 0,06870331 ! forebrain development GO:0030900 131 80 1,000 5,347E-03 0,06832163 ! response to protein stimulus GO:0051789 111 81 1,000 5,478E-03 0,0696061 ! positive regulation of cell activation GO:0050867 120 81 1,000 5,478E-03 0,06922365 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell adhesion GO:0030155 159 83 1,000 5,744E-03 0,07218822 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 5,879E-03 0,07348562 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 6,015E-03 0,07478709 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 6,015E-03 0,07438501 ! cell cycle arrest GO:0007050 150 86 1,000 6,154E-03 0,07568561 ! establishment of RNA localization GO:0051236 128 88 1,000 6,434E-03 0,0787148 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,846E-03 0,0833131 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 6,846E-03 0,08287461 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 6,846E-03 0,08244071 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 6,846E-03 0,08201133 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,846E-03 0,0815864 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 6,846E-03 0,08116585 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,846E-03 0,08074962 ! sleep GO:0030431 11 5 0,000 6,846E-03 0,08033763 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,846E-03 0,07992982 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,846E-03 0,07952614 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,846E-03 0,07912651 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 6,846E-03 0,07873088 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 6,846E-03 0,07833918 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 6,846E-03 0,07795136 ! tongue development GO:0043586 6 5 0,000 6,846E-03 0,07756737 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 6,846E-03 0,07718713 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,846E-03 0,07681061 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 6,846E-03 0,07643774 ! cobalt ion transport GO:0006824 9 5 0,000 6,846E-03 0,07606848 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,846E-03 0,07570277 ! SMAD protein complex assembly GO:0007183 9 5 0,000 6,846E-03 0,07534055 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,846E-03 0,07498179 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,846E-03 0,07462642 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 6,846E-03 0,07427441 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,846E-03 0,07392571 ! embryonic camera-type eye development GO:0031076 8 5 0,000 6,846E-03 0,07358026 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 6,846E-03 0,07323803 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 6,846E-03 0,07289896 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,846E-03 0,07256302 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,846E-03 0,07223016 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,846E-03 0,07190034 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 6,846E-03 0,07157352 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 6,846E-03 0,07124966 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,846E-03 0,07092872 ! malate metabolic process GO:0006108 7 5 0,000 6,846E-03 0,07061065 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 6,846E-03 0,07029543 ! behavioral response to pain GO:0048266 7 5 0,000 6,846E-03 0,069983 ! clathrin coat assembly GO:0048268 11 5 0,000 6,846E-03 0,06967334 ! phototransduction, visible light GO:0007603 6 5 0,000 6,846E-03 0,06936641 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,846E-03 0,06906217 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,846E-03 0,06876059 ! mating behavior GO:0007617 6 5 0,000 6,846E-03 0,06846163 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,846E-03 0,06816526 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,846E-03 0,06787145 ! rhythmic behavior GO:0007622 12 5 0,000 6,846E-03 0,06758015 ! copulation GO:0007620 7 5 0,000 6,846E-03 0,06729135 ! glial cell fate commitment GO:0021781 12 5 0,000 6,846E-03 0,067005 ! protein maturation by protein folding GO:0022417 12 5 0,000 6,846E-03 0,06672108 ! embryonic hemopoiesis GO:0035162 10 5 0,000 6,846E-03 0,06643956 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,846E-03 0,0661604 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 6,846E-03 0,06588358 ! apoptotic cell clearance GO:0043277 13 5 0,000 6,846E-03 0,06560906 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,846E-03 0,06533683 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 6,846E-03 0,06506684 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,846E-03 0,06479908 ! response to protozoan GO:0001562 9 5 0,000 6,846E-03 0,06453351 ! positive regulation of glycolysis GO:0045821 11 5 0,000 6,846E-03 0,0642701 ! lymph vessel development GO:0001945 7 5 0,000 6,846E-03 0,06400884 ! endochondral ossification GO:0001958 12 5 0,000 6,846E-03 0,0637497 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,846E-03 0,06349264 ! parathyroid gland development GO:0060017 8 5 0,000 6,846E-03 0,06323765 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 6,846E-03 0,0629847 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,846E-03 0,06273377 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 6,846E-03 0,06248482 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 6,846E-03 0,06223785 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,846E-03 0,06199282 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 6,846E-03 0,06174971 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 6,846E-03 0,0615085 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 6,846E-03 0,06126917 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,846E-03 0,06103169 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,846E-03 0,06079604 ! cardiac muscle fiber development GO:0048739 7 5 0,000 6,846E-03 0,06056221 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 6,846E-03 0,06033017 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 6,846E-03 0,06009991 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,846E-03 0,05987139 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,846E-03 0,0596446 ! ovulation GO:0030728 6 5 0,000 6,846E-03 0,05941953 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,846E-03 0,05919615 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 6,846E-03 0,05897444 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,846E-03 0,05875439 ! response to pH GO:0009268 9 5 0,000 6,846E-03 0,05853597 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,846E-03 0,05831917 ! proline biosynthetic process GO:0006561 6 5 0,000 6,846E-03 0,05810397 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,846E-03 0,05789035 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 6,846E-03 0,0576783 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,846E-03 0,05746779 ! polyol catabolic process GO:0046174 7 5 0,000 6,846E-03 0,05725882 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,846E-03 0,05705136 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,846E-03 0,0568454 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,846E-03 0,05664092 ! sister chromatid cohesion GO:0007062 9 5 0,000 6,846E-03 0,0564379 ! nerve growth factor processing GO:0032455 7 5 0,000 6,846E-03 0,05623634 ! urea metabolic process GO:0019627 6 5 0,000 6,846E-03 0,05603621 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 6,846E-03 0,0558375 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,846E-03 0,0556402 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 6,846E-03 0,05544428 ! neutrophil activation GO:0042119 5 5 0,000 6,846E-03 0,05524974 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,846E-03 0,05505656 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,846E-03 0,05486472 ! response to food GO:0032094 5 5 0,000 6,846E-03 0,05467422 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,846E-03 0,05448504 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,846E-03 0,05429716 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,846E-03 0,05411057 ! forebrain neuron development GO:0021884 7 5 0,000 6,846E-03 0,05392526 ! melanosome organization GO:0032438 7 5 0,000 6,846E-03 0,05374121 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,846E-03 0,05355842 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,846E-03 0,05337687 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 6,846E-03 0,05319654 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,846E-03 0,05301743 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 6,846E-03 0,05283951 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 6,846E-03 0,05266279 ! nucleoside transport GO:0015858 6 5 0,000 6,846E-03 0,05248725 ! nucleoside salvage GO:0043174 7 5 0,000 6,846E-03 0,05231288 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 6,846E-03 0,05213965 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,846E-03 0,05196758 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 6,846E-03 0,05179663 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,846E-03 0,0516268 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,846E-03 0,05145809 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,846E-03 0,05129047 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,846E-03 0,05112395 ! depyrimidination GO:0045008 8 5 0,000 6,846E-03 0,0509585 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 6,846E-03 0,05079411 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,846E-03 0,05063079 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 6,846E-03 0,05046851 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,846E-03 0,05030727 ! neuronal ion channel clustering GO:0045161 7 5 0,000 6,846E-03 0,05014706 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,846E-03 0,04998786 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 6,846E-03 0,04982967 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 6,846E-03 0,04967248 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,846E-03 0,04951628 ! monocyte differentiation GO:0030224 8 5 0,000 6,846E-03 0,04936105 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 6,846E-03 0,0492068 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 6,846E-03 0,04905351 ! centrosome duplication GO:0051298 5 5 0,000 6,846E-03 0,04890117 ! response to UV-C GO:0010225 6 5 0,000 6,846E-03 0,04874977 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,846E-03 0,04859931 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 6,846E-03 0,04844977 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,846E-03 0,04830115 ! regulation of dendrite development GO:0050773 12 5 0,000 6,846E-03 0,04815344 ! peptidyl-arginine modification GO:0018195 7 5 0,000 6,846E-03 0,04800663 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,846E-03 0,04786072 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 6,846E-03 0,04771568 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 6,846E-03 0,04757153 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 6,846E-03 0,04742824 ! regulation of dopamine secretion GO:0014059 12 5 0,000 6,846E-03 0,04728581 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,846E-03 0,04714424 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 6,846E-03 0,04700351 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,846E-03 0,04686362 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,846E-03 0,04672456 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 6,846E-03 0,04658632 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,846E-03 0,0464489 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 6,846E-03 0,04631228 ! neural tube patterning GO:0021532 6 5 0,000 6,846E-03 0,04617647 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,846E-03 0,04604145 ! histone demethylation GO:0016577 9 5 0,000 6,846E-03 0,04590722 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,846E-03 0,04577377 ! regulation of sterol transport GO:0032371 7 5 0,000 6,846E-03 0,04564109 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,846E-03 0,04550918 ! enteric nervous system development GO:0048484 8 5 0,000 6,846E-03 0,04537803 ! establishment of planar polarity GO:0001736 6 5 0,000 6,846E-03 0,04524763 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,846E-03 0,04511798 ! muscle cell proliferation GO:0033002 8 5 0,000 6,846E-03 0,04498907 ! transcription termination GO:0006353 8 5 0,000 6,846E-03 0,0448609 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 6,846E-03 0,04473345 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 6,846E-03 0,04460673 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 6,846E-03 0,04448072 ! regulation of respiratory burst GO:0060263 8 5 0,000 6,846E-03 0,04435542 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,846E-03 0,04423083 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,846E-03 0,04410693 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,846E-03 0,04398373 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 6,846E-03 0,04386121 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,846E-03 0,04373938 ! apical protein localization GO:0045176 6 5 0,000 6,846E-03 0,04361821 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,846E-03 0,04349772 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,846E-03 0,04337789 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,846E-03 0,04325872 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,846E-03 0,04314021 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 6,846E-03 0,04302234 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 6,846E-03 0,04290511 ! triglyceride catabolic process GO:0019433 6 5 0,000 6,846E-03 0,04278852 ! glial cell migration GO:0008347 10 5 0,000 6,846E-03 0,04267256 ! determination of adult lifespan GO:0008340 8 5 0,000 6,846E-03 0,04255723 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,846E-03 0,04244252 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,846E-03 0,04232843 ! somatic stem cell maintenance GO:0035019 13 5 0,000 6,846E-03 0,04221495 ! cerebellar cortex formation GO:0021697 6 5 0,000 6,846E-03 0,04210207 ! neural plate development GO:0001840 6 5 0,000 6,846E-03 0,0419898 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 6,846E-03 0,04187813 ! regulation of sensory perception GO:0051931 6 5 0,000 6,846E-03 0,04176704 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 6,846E-03 0,04165655 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 6,846E-03 0,04154664 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 6,846E-03 0,0414373 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 6,846E-03 0,04132854 ! sensory cilium assembly GO:0035058 6 5 0,000 6,846E-03 0,04122035 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 6,846E-03 0,04111273 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,846E-03 0,04100567 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 6,846E-03 0,04089916 ! spindle assembly GO:0051225 5 5 0,000 6,846E-03 0,0407932 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 6,846E-03 0,04068779 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 6,846E-03 0,04058293 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,846E-03 0,0404786 ! organ regeneration GO:0031100 7 5 0,000 6,846E-03 0,04037481 ! NAD biosynthetic process GO:0009435 7 5 0,000 6,846E-03 0,04027155 ! carnitine metabolic process GO:0009437 5 5 0,000 6,846E-03 0,04016881 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 6,846E-03 0,0400666 ! cellular anion homeostasis GO:0030002 6 5 0,000 6,846E-03 0,03996491 GO:0055081|anion homeostasis, ! RNA localization GO:0006403 135 91 1,000 6,866E-03 0,03997712 ! cell fate commitment GO:0045165 141 92 1,000 7,012E-03 0,0407283 ! DNA recombination GO:0006310 146 92 1,000 7,012E-03 0,04062571 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 7,16E-03 0,04137972 ! angiogenesis GO:0001525 149 95 1,000 7,461E-03 0,04300842 ! carboxylic acid transport GO:0046942 147 95 1,000 7,461E-03 0,0429009 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 7,613E-03 0,04366797 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 7,613E-03 0,04355935 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 8,079E-03 0,04610858 ! tRNA transcription GO:0009304 11 6 0,000 8,21E-03 0,04674007 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 8,21E-03 0,04662466 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 8,21E-03 0,04650983 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 8,21E-03 0,04639555 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,21E-03 0,04628184 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 8,21E-03 0,04616868 ! regulation of helicase activity GO:0051095 11 6 0,000 8,21E-03 0,04605607 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 8,21E-03 0,04594401 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 8,21E-03 0,0458325 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 8,21E-03 0,04572152 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 8,21E-03 0,04561108 ! positive regulation of axon extension GO:0045773 8 6 0,000 8,21E-03 0,04550118 ! prostate gland development GO:0030850 9 6 0,000 8,21E-03 0,0453918 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 8,21E-03 0,04528295 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 8,21E-03 0,04517462 ! forebrain neuron differentiation GO:0021879 9 6 0,000 8,21E-03 0,0450668 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 8,21E-03 0,0449595 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 8,21E-03 0,04485271 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 8,21E-03 0,04474642 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 8,21E-03 0,04464064 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 8,21E-03 0,04453535 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 8,21E-03 0,04443056 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 8,21E-03 0,04432627 ! neuron adhesion GO:0007158 9 6 0,000 8,21E-03 0,04422246 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 8,21E-03 0,04411913 ! establishment of tissue polarity GO:0007164 7 6 0,000 8,21E-03 0,04401629 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 8,21E-03 0,04391393 ! signal peptide processing GO:0006465 8 6 0,000 8,21E-03 0,04381204 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 8,21E-03 0,04371062 ! mRNA stabilization GO:0048255 15 6 0,000 8,21E-03 0,04360967 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 8,21E-03 0,04350919 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 8,21E-03 0,04340917 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 8,21E-03 0,04330961 ! opsonization GO:0008228 8 6 0,000 8,21E-03 0,0432105 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 8,21E-03 0,04311185 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 8,21E-03 0,04301364 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 8,21E-03 0,04291588 ! protein amino acid dealkylation GO:0008214 11 6 0,000 8,21E-03 0,04281857 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 8,21E-03 0,04272169 ! photoreceptor cell development GO:0042461 10 6 0,000 8,21E-03 0,04262526 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 8,21E-03 0,04252925 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 8,21E-03 0,04243368 ! mechanosensory behavior GO:0007638 8 6 0,000 8,21E-03 0,04233854 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 8,21E-03 0,04224382 ! negative regulation of endocytosis GO:0045806 8 6 0,000 8,21E-03 0,04214953 ! response to interferon-gamma GO:0034341 12 6 0,000 8,21E-03 0,04205565 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 8,21E-03 0,0419622 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 8,21E-03 0,04186916 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,21E-03 0,04177652 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 8,21E-03 0,0416843 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 8,21E-03 0,04159249 ! cGMP-mediated signaling GO:0019934 10 6 0,000 8,21E-03 0,04150107 ! activation of MAPKKK activity GO:0000185 10 6 0,000 8,21E-03 0,04141006 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 8,21E-03 0,04131945 ! thymic T cell selection GO:0045061 12 6 0,000 8,21E-03 0,04122923 ! protein lipoylation GO:0009249 10 6 0,000 8,21E-03 0,04113941 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 8,21E-03 0,04104998 ! pigment granule organization GO:0048753 11 6 0,000 8,21E-03 0,04096093 ! drug transport GO:0015893 6 6 0,000 8,21E-03 0,04087227 ! cysteine metabolic process GO:0006534 7 6 0,000 8,21E-03 0,04078399 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 8,21E-03 0,0406961 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 8,21E-03 0,04060858 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,21E-03 0,04052144 ! histidine metabolic process GO:0006547 6 6 0,000 8,21E-03 0,04043467 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 8,21E-03 0,04034827 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 8,21E-03 0,04026224 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 8,21E-03 0,04017657 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 8,21E-03 0,04009127 ! adenohypophysis development GO:0021984 10 6 0,000 8,21E-03 0,04000633 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 8,21E-03 0,03992175 ! hyperosmotic response GO:0006972 8 6 0,000 8,21E-03 0,03983753 ! microtubule nucleation GO:0007020 10 6 0,000 8,21E-03 0,03975366 ! ER overload response GO:0006983 7 6 0,000 8,21E-03 0,03967015 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 8,21E-03 0,03958698 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 8,21E-03 0,03950416 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 8,21E-03 0,03942169 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 8,21E-03 0,03933956 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 8,21E-03 0,03925777 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 8,21E-03 0,03917633 ! response to dietary excess GO:0002021 7 6 0,000 8,21E-03 0,03909522 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 8,21E-03 0,03901444 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 8,21E-03 0,038934 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 8,21E-03 0,03885389 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 8,21E-03 0,0387741 ! glycerol ether catabolic process GO:0044269 8 6 0,000 8,21E-03 0,03869465 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 8,21E-03 0,03861552 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,21E-03 0,03853671 ! neuron apoptosis GO:0051402 8 6 0,000 8,21E-03 0,03845823 ! organic alcohol transport GO:0015850 9 6 0,000 8,21E-03 0,03838006 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 8,21E-03 0,03830221 ! T cell mediated immunity GO:0002456 12 6 0,000 8,21E-03 0,03822467 ! male sex determination GO:0030238 9 6 0,000 8,21E-03 0,03814745 ! carnitine transport GO:0015879 8 6 0,000 8,21E-03 0,03807054 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 8,21E-03 0,03799394 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 8,21E-03 0,03791765 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,21E-03 0,03784166 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 8,21E-03 0,03776598 ! positive regulation of exocytosis GO:0045921 6 6 0,000 8,21E-03 0,0376906 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 8,21E-03 0,03761552 ! parturition GO:0007567 12 6 0,000 8,21E-03 0,03754073 ! negative regulation of translational initiation GO:0045947 7 6 0,000 8,21E-03 0,03746625 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 8,21E-03 0,03739206 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 8,21E-03 0,03731816 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 8,21E-03 0,03724455 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 8,21E-03 0,03717124 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 8,21E-03 0,03709821 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 8,21E-03 0,03702547 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 8,21E-03 0,03695301 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 8,21E-03 0,03688084 ! macrophage differentiation GO:0030225 10 6 0,000 8,21E-03 0,03680895 ! astrocyte development GO:0014002 14 6 0,000 8,21E-03 0,03673733 ! hyaluronan metabolic process GO:0030212 6 6 0,000 8,21E-03 0,036666 ! purine base biosynthetic process GO:0009113 14 6 0,000 8,21E-03 0,03659494 ! interaction with symbiont GO:0051702 8 6 0,000 8,21E-03 0,03652416 ! anterograde axon cargo transport GO:0008089 8 6 0,000 8,21E-03 0,03645365 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,21E-03 0,03638341 ! eating behavior GO:0042755 6 6 0,000 8,21E-03 0,03631344 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 8,21E-03 0,03624374 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 8,21E-03 0,03617431 ! response to copper ion GO:0046688 9 6 0,000 8,21E-03 0,03610514 ! DNA topological change GO:0006265 8 6 0,000 8,21E-03 0,03603624 ! response to exogenous dsRNA GO:0043330 8 6 0,000 8,21E-03 0,0359676 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 8,21E-03 0,03589922 ! establishment of melanosome localization GO:0032401 9 6 0,000 8,21E-03 0,0358311 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,21E-03 0,03576324 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,21E-03 0,03569563 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 8,21E-03 0,03562828 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 8,21E-03 0,03556118 ! nucleoside catabolic process GO:0009164 6 6 0,000 8,21E-03 0,03549434 ! gas homeostasis GO:0033483 11 6 0,000 8,21E-03 0,03542775 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 8,21E-03 0,0353614 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 8,21E-03 0,03529531 ! Schwann cell development GO:0014044 14 6 0,000 8,21E-03 0,03522946 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 8,21E-03 0,03516385 ! dendrite morphogenesis GO:0048813 9 6 0,000 8,21E-03 0,03509849 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,21E-03 0,03503337 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 8,21E-03 0,0349685 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 8,21E-03 0,03490386 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 8,21E-03 0,03483946 ! histone ubiquitination GO:0016574 7 6 0,000 8,21E-03 0,0347753 ! regulation of meiosis GO:0040020 10 6 0,000 8,21E-03 0,03471138 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 8,21E-03 0,03464769 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 8,21E-03 0,03458423 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 8,21E-03 0,034521 ! regulation of mast cell activation GO:0033003 6 6 0,000 8,21E-03 0,03445801 ! membrane to membrane docking GO:0022614 12 6 0,000 8,21E-03 0,03439524 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 8,21E-03 0,03433271 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 8,21E-03 0,0342704 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 8,21E-03 0,03420831 ! receptor internalization GO:0031623 9 6 0,000 8,21E-03 0,03414645 ! neutrophil homeostasis GO:0001780 6 6 0,000 8,21E-03 0,03408482 ! coenzyme A metabolic process GO:0015936 9 6 0,000 8,21E-03 0,0340234 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,21E-03 0,03396221 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 8,21E-03 0,03390124 ! protein deubiquitination GO:0016579 8 6 0,000 8,21E-03 0,03384048 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 8,21E-03 0,03377994 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 8,21E-03 0,03371962 ! peptidyl-histidine modification GO:0018202 9 6 0,000 8,21E-03 0,03365952 ! axonal fasciculation GO:0007413 9 6 0,000 8,21E-03 0,03359962 ! thiamin metabolic process GO:0006772 6 6 0,000 8,21E-03 0,03353995 ! midbrain development GO:0030901 6 6 0,000 8,21E-03 0,03348048 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,21E-03 0,03342122 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 8,21E-03 0,03336217 ! progesterone metabolic process GO:0042448 8 6 0,000 8,21E-03 0,03330333 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,21E-03 0,0332447 ! glycolipid catabolic process GO:0019377 13 6 0,000 8,21E-03 0,03318627 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 8,21E-03 0,03312805 ! positive regulation of glucose import GO:0046326 6 6 0,000 8,21E-03 0,03307003 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 8,21E-03 0,03301222 ! adult feeding behavior GO:0008343 6 6 0,000 8,21E-03 0,03295461 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 8,21E-03 0,03289719 ! blastocyst growth GO:0001832 15 6 0,000 8,21E-03 0,03283998 ! pigment granule transport GO:0051904 12 6 0,000 8,21E-03 0,03278297 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 8,21E-03 0,03272615 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 8,21E-03 0,03266953 ! catecholamine transport GO:0051937 7 6 0,000 8,21E-03 0,03261311 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,21E-03 0,03255688 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 8,21E-03 0,03250084 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 8,21E-03 0,032445 ! negative regulation of B cell activation GO:0050869 9 6 0,000 8,21E-03 0,03238935 ! protein prenylation GO:0018342 10 6 0,000 8,21E-03 0,03233389 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,21E-03 0,03227861 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 8,21E-03 0,03222353 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 8,21E-03 0,03216864 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 8,21E-03 0,03211393 ! positive regulation of coagulation GO:0050820 11 6 0,000 8,21E-03 0,0320594 ! regulation of translation GO:0006417 151 100 1,000 8,237E-03 0,03211045 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 9,572E-03 0,03725156 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 9,572E-03 0,03718864 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 9,572E-03 0,03712593 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 9,572E-03 0,03706342 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 9,572E-03 0,03700113 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,572E-03 0,03693905 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 9,572E-03 0,03687718 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,572E-03 0,03681551 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 9,572E-03 0,03675405 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 9,572E-03 0,03669279 ! reproductive behavior GO:0019098 12 7 0,000 9,572E-03 0,03663174 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 9,572E-03 0,03657089 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 9,572E-03 0,03651024 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 9,572E-03 0,03644979 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 9,572E-03 0,03638954 ! oligopeptide transport GO:0006857 11 7 0,000 9,572E-03 0,0363295 ! protein amino acid sulfation GO:0006477 9 7 0,000 9,572E-03 0,03626964 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 9,572E-03 0,03620999 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 9,572E-03 0,03615053 ! RNA methylation GO:0001510 11 7 0,000 9,572E-03 0,03609127 ! pericardium development GO:0060039 8 7 0,000 9,572E-03 0,0360322 ! macrophage chemotaxis GO:0048246 10 7 0,000 9,572E-03 0,03597332 ! fibril organization GO:0043206 13 7 0,000 9,572E-03 0,03591464 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 9,572E-03 0,03585615 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,572E-03 0,03579784 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,572E-03 0,03573973 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 9,572E-03 0,03568181 ! lipoprotein transport GO:0042953 9 7 0,000 9,572E-03 0,03562407 ! cerebral cortex cell migration GO:0021795 11 7 0,000 9,572E-03 0,03556652 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,572E-03 0,03550915 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,572E-03 0,03545197 ! estrogen metabolic process GO:0008210 14 7 0,000 9,572E-03 0,03539497 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 9,572E-03 0,03533816 ! chemosensory behavior GO:0007635 9 7 0,000 9,572E-03 0,03528153 ! microtubule bundle formation GO:0001578 8 7 0,000 9,572E-03 0,03522508 ! T-helper 1 type immune response GO:0042088 11 7 0,000 9,572E-03 0,03516881 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 9,572E-03 0,03511272 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 9,572E-03 0,03505681 ! leukocyte degranulation GO:0043299 10 7 0,000 9,572E-03 0,03500107 ! bile acid and bile salt transport GO:0015721 9 7 0,000 9,572E-03 0,03494551 ! reflex GO:0060004 12 7 0,000 9,572E-03 0,03489013 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,572E-03 0,03483493 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,572E-03 0,0347799 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,572E-03 0,03472504 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 9,572E-03 0,03467035 ! glycerolipid catabolic process GO:0046503 9 7 0,000 9,572E-03 0,03461584 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,572E-03 0,0345615 ! spinal cord patterning GO:0021511 7 7 0,000 9,572E-03 0,03450733 ! hemoglobin metabolic process GO:0020027 10 7 0,000 9,572E-03 0,03445332 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 9,572E-03 0,03439949 ! adrenal gland development GO:0030325 17 7 0,000 9,572E-03 0,03434583 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 9,572E-03 0,03429233 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 9,572E-03 0,034239 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 9,572E-03 0,03418583 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 9,572E-03 0,03413283 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 9,572E-03 0,03407999 ! endosome organization GO:0007032 10 7 0,000 9,572E-03 0,03402732 ! thyroid hormone generation GO:0006590 11 7 0,000 9,572E-03 0,03397481 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 9,572E-03 0,03392246 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 9,572E-03 0,03387027 ! regulation of pigmentation during development GO:0048070 15 7 0,000 9,572E-03 0,03381824 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,572E-03 0,03376637 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 9,572E-03 0,03371466 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,572E-03 0,03366311 ! galactose metabolic process GO:0006012 10 7 0,000 9,572E-03 0,03361172 ! vesicle fusion GO:0006906 15 7 0,000 9,572E-03 0,03356048 ! intracellular pH reduction GO:0051452 10 7 0,000 9,572E-03 0,0335094 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 9,572E-03 0,03345847 ! organ growth GO:0035265 11 7 0,000 9,572E-03 0,0334077 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 9,572E-03 0,03335708 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 9,572E-03 0,03330662 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,572E-03 0,03325631 ! retinol metabolic process GO:0042572 9 7 0,000 9,572E-03 0,03320615 ! behavioral fear response GO:0001662 13 7 0,000 9,572E-03 0,03315614 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 9,572E-03 0,03310628 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 9,572E-03 0,03305657 ! rRNA modification GO:0000154 12 7 0,000 9,572E-03 0,03300701 ! protein heterooligomerization GO:0051291 10 7 0,000 9,572E-03 0,0329576 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,572E-03 0,03290833 ! response to UV-B GO:0010224 11 7 0,000 9,572E-03 0,03285922 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 9,572E-03 0,03281024 ! protein retention in ER lumen GO:0006621 12 7 0,000 9,572E-03 0,03276142 ! intermediate filament organization GO:0045109 11 7 0,000 9,572E-03 0,03271274 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 9,572E-03 0,03266421 ! cardiac muscle cell development GO:0055013 9 7 0,000 9,572E-03 0,03261581 ! fibrinolysis GO:0042730 9 7 0,000 9,572E-03 0,03256757 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 9,572E-03 0,03251946 ! regulation of circadian rhythm GO:0042752 11 7 0,000 9,572E-03 0,0324715 ! B cell lineage commitment GO:0002326 17 7 0,000 9,572E-03 0,03242367 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 9,572E-03 0,03237599 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 9,572E-03 0,03232845 ! response to tropane GO:0014073 13 7 0,000 9,572E-03 0,03228105 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 9,572E-03 0,03223378 ! melanosome localization GO:0032400 10 7 0,000 9,572E-03 0,03218666 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 9,572E-03 0,03213967 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 9,572E-03 0,03209282 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 9,572E-03 0,03204611 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 9,572E-03 0,03199953 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 9,572E-03 0,03195308 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 9,572E-03 0,03190677 ! mast cell activation GO:0045576 9 7 0,000 9,572E-03 0,0318606 ! multicellular organismal aging GO:0010259 11 7 0,000 9,572E-03 0,03181456 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 9,572E-03 0,03176865 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 9,572E-03 0,03172287 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 9,572E-03 0,03167723 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 9,572E-03 0,03163172 ! establishment of nucleus localization GO:0040023 13 7 0,000 9,572E-03 0,03158633 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 9,572E-03 0,03154108 ! T cell lineage commitment GO:0002360 12 7 0,000 9,572E-03 0,03149596 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 9,572E-03 0,03145096 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 9,572E-03 0,0314061 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 9,572E-03 0,03136136 ! regulation of lipid transport GO:0032368 13 7 0,000 9,572E-03 0,03131675 ! response to tumor cell GO:0002347 12 7 0,000 9,572E-03 0,03127226 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 9,572E-03 0,03122791 ! neuroblast proliferation GO:0007405 13 7 0,000 9,572E-03 0,03118367 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 9,572E-03 0,03113957 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 9,572E-03 0,03109559 ! peptidyl-threonine modification GO:0018210 18 7 0,000 9,572E-03 0,03105173 ! diuresis GO:0030146 12 7 0,000 9,572E-03 0,03100799 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 9,572E-03 0,03096438 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,572E-03 0,03092089 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 9,572E-03 0,03087752 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,572E-03 0,03083428 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,572E-03 0,03079115 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,572E-03 0,03074815 ! regulation of synaptogenesis GO:0051963 10 7 0,000 9,572E-03 0,03070526 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 9,572E-03 0,0306625 ! dopamine biosynthetic process GO:0042416 15 7 0,000 9,572E-03 0,03061985 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 9,572E-03 0,03057733 ! lymph node development GO:0048535 9 7 0,000 9,572E-03 0,03053492 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 9,572E-03 0,03049262 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 9,572E-03 0,03045045 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,572E-03 0,03040839 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 9,572E-03 0,03036645 ! endosome to lysosome transport GO:0008333 10 7 0,000 9,572E-03 0,03032462 ! ATP catabolic process GO:0006200 10 7 0,000 9,572E-03 0,03028291 ! establishment of pigment granule localization GO:0051905 13 7 0,000 9,572E-03 0,03024131 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 9,572E-03 0,03019983 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 9,572E-03 0,03015846 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 9,572E-03 0,0301172 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 9,572E-03 0,03007606 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 9,572E-03 0,03003503 ! muscle adaptation GO:0043500 12 7 0,000 9,572E-03 0,02999411 ! amino sugar catabolic process GO:0046348 9 7 0,000 9,572E-03 0,0299533 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 9,572E-03 0,0299126 ! retina homeostasis GO:0001895 9 7 0,000 9,572E-03 0,02987201 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 9,572E-03 0,02983154 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 9,572E-03 0,02979117 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 9,572E-03 0,02975091 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 9,572E-03 0,02971076 ! behavioral response to nicotine GO:0035095 11 7 0,000 9,572E-03 0,02967072 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,572E-03 0,02963079 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,572E-03 0,02959096 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01093228 0,03375065 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01093228 0,03370541 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01093228 0,03366029 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01093228 0,03361529 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01093228 0,03357041 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01093228 0,03352565 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01093228 0,03348101 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01093228 0,03343648 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01093228 0,03339208 ! phosphate transport GO:0006817 10 8 0,000 0,01093228 0,03334779 ! N-glycan processing GO:0006491 12 8 0,000 0,01093228 0,03330362 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01093228 0,03325957 ! UTP metabolic process GO:0046051 8 8 0,000 0,01093228 0,03321564 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01093228 0,03317182 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01093228 0,03312811 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01093228 0,03308452 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01093228 0,03304105 ! succinate metabolic process GO:0006105 14 8 0,000 0,01093228 0,03299769 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01093228 0,03295444 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01093228 0,0329113 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01093228 0,03286828 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01093228 0,03282537 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01093228 0,03278258 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01093228 0,03273989 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01093228 0,03269732 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01093228 0,03265485 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01093228 0,0326125 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01093228 0,03257025 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01093228 0,03252812 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01093228 0,03248609 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01093228 0,03244418 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01093228 0,03240237 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01093228 0,03236066 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01093228 0,03231907 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01093228 0,03227758 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01093228 0,0322362 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01093228 0,03219493 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01093228 0,03215376 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01093228 0,03211269 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01093228 0,03207173 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01093228 0,03203087 ! melanin metabolic process GO:0006582 12 8 0,000 0,01093228 0,03199012 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01093228 0,03194947 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01093228 0,03190893 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01093228 0,03186849 ! macrophage activation GO:0042116 12 8 0,000 0,01093228 0,03182815 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01093228 0,03178791 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01093228 0,03174777 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01093228 0,03170774 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01093228 0,0316678 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01093228 0,03162797 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01093228 0,03158824 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01093228 0,0315486 ! ruffle organization GO:0031529 11 8 0,000 0,01093228 0,03150907 ! osteoblast development GO:0002076 13 8 0,000 0,01093228 0,03146963 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01093228 0,0314303 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01093228 0,03139106 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01093228 0,03135192 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01093228 0,03131287 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01093228 0,03127393 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01093228 0,03123508 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01093228 0,03119632 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01093228 0,03115767 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01093228 0,0311191 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01093228 0,03108064 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01093228 0,03104227 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01093228 0,03100399 ! segment specification GO:0007379 10 8 0,000 0,01093228 0,03096581 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01093228 0,03092772 ! cellular extravasation GO:0045123 11 8 0,000 0,01093228 0,03088973 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01093228 0,03085182 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01093228 0,03081402 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01093228 0,0307763 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01093228 0,03073868 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01093228 0,03070114 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01093228 0,0306637 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01093228 0,03062635 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01093228 0,0305891 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01093228 0,03055193 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01093228 0,03051485 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01093228 0,03047786 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01093228 0,03044096 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01093228 0,03040416 ! induction of an organ GO:0001759 11 8 0,000 0,01093228 0,03036744 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01093228 0,0303308 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01093228 0,03029426 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01093228 0,03025781 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01093228 0,03022144 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01093228 0,03018516 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01093228 0,03014896 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01093228 0,03011286 ! sterol catabolic process GO:0016127 9 8 0,000 0,01093228 0,03007684 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01093228 0,0300409 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01093228 0,03000506 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01093228 0,02996929 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01093228 0,02993361 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01093228 0,02989802 ! prophase GO:0051324 11 8 0,000 0,01093228 0,02986251 ! S phase GO:0051320 8 8 0,000 0,01093228 0,02982709 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01093228 0,02979175 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01093228 0,02975649 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01093228 0,02972132 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01093228 0,02968623 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01093228 0,02965122 ! hormone catabolic process GO:0042447 13 8 0,000 0,01093228 0,0296163 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01093228 0,02958145 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01093228 0,02954669 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01093228 0,02951201 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01093228 0,02947742 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01093228 0,0294429 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01093228 0,02940846 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01093228 0,02937411 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01093228 0,02933983 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01093228 0,02930564 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01093228 0,02927152 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01093228 0,02923748 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01093228 0,02920353 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01093228 0,02916965 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01093228 0,02913585 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01093228 0,02910213 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01093228 0,02906848 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01229073 0,03264282 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01229073 0,03260517 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01229073 0,0325676 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01229073 0,03253013 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01229073 0,03249274 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01229073 0,03245543 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01229073 0,03241821 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01229073 0,03238108 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01229073 0,03234403 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01229073 0,03230706 ! GTP metabolic process GO:0046039 9 9 0,000 0,01229073 0,03227018 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01229073 0,03223339 ! social behavior GO:0035176 14 9 0,000 0,01229073 0,03219668 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01229073 0,03216005 ! artery development GO:0060840 19 9 0,000 0,01229073 0,0321235 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01229073 0,03208704 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01229073 0,03205066 ! response to pain GO:0048265 16 9 0,000 0,01229073 0,03201436 ! protein complex disassembly GO:0043241 17 9 0,000 0,01229073 0,03197815 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01229073 0,03194201 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01229073 0,03190596 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01229073 0,03186999 ! lung alveolus development GO:0048286 17 9 0,000 0,01229073 0,0318341 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01229073 0,03179829 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01229073 0,03176256 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01229073 0,03172691 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01229073 0,03169135 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01229073 0,03165586 ! protein targeting to ER GO:0045047 19 9 0,000 0,01229073 0,03162045 ! T cell selection GO:0045058 18 9 0,000 0,01229073 0,03158512 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01229073 0,03154987 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01229073 0,03151469 ! arginine catabolic process GO:0006527 10 9 0,000 0,01229073 0,0314796 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01229073 0,03144458 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01229073 0,03140965 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01229073 0,03137478 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01229073 0,03134 GO:0006600|creatine metabolic process, ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01229073 0,03130529 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01229073 0,03127066 ! mannose metabolic process GO:0006013 9 9 0,000 0,01229073 0,03123611 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01229073 0,03120163 ! receptor clustering GO:0043113 15 9 0,000 0,01229073 0,03116723 ! epithelial cell development GO:0002064 10 9 0,000 0,01229073 0,03113291 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01229073 0,03109866 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01229073 0,03106448 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01229073 0,03103039 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01229073 0,03099636 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01229073 0,03096241 ! motor axon guidance GO:0008045 14 9 0,000 0,01229073 0,03092853 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01229073 0,03089473 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01229073 0,03086101 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01229073 0,03082735 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01229073 0,03079377 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01229073 0,03076026 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01229073 0,03072683 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01229073 0,03069346 ! response to amine stimulus GO:0014075 13 9 0,000 0,01229073 0,03066017 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01229073 0,03062696 ! erythrocyte development GO:0048821 11 9 0,000 0,01229073 0,03059381 ! renal water homeostasis GO:0003091 14 9 0,000 0,01229073 0,03056074 ! postreplication repair GO:0006301 11 9 0,000 0,01229073 0,03052773 ! mRNA cleavage GO:0006379 13 9 0,000 0,01229073 0,0304948 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01229073 0,03046194 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01229073 0,03042915 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01229073 0,03039643 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01229073 0,03036378 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01229073 0,0303312 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01229073 0,03029869 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01229073 0,03026625 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01229073 0,03023388 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01229073 0,03020158 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01229073 0,03016935 ! purine base metabolic process GO:0006144 18 9 0,000 0,01229073 0,03013719 ! oocyte differentiation GO:0009994 12 9 0,000 0,01229073 0,03010509 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01229073 0,03007306 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01229073 0,03004111 ! spleen development GO:0048536 15 9 0,000 0,01229073 0,03000922 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01229073 0,02997739 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01229073 0,02994564 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01229073 0,02991395 ! detection of calcium ion GO:0005513 13 9 0,000 0,01229073 0,02988233 ! blastocyst formation GO:0001825 12 9 0,000 0,01229073 0,02985077 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01229073 0,02981928 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01229073 0,02978786 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01229073 0,02975651 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01229073 0,02972522 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01229073 0,02969399 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01229073 0,02966283 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01229073 0,02963174 ! prepulse inhibition GO:0060134 14 9 0,000 0,01229073 0,02960071 ! embryonic placenta development GO:0001892 12 9 0,000 0,01229073 0,02956975 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01229073 0,02953885 ! insulin secretion GO:0030073 17 9 0,000 0,01229073 0,02950802 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01229073 0,02947725 ! response to nicotine GO:0035094 16 9 0,000 0,01229073 0,02944654 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01229073 0,0294159 ! nucleus localization GO:0051647 15 9 0,000 0,01229073 0,02938532 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01229073 0,02935481 ! localization within membrane GO:0051668 15 9 0,000 0,01229073 0,02932436 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,0136474 0,03252747 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0136474 0,0324938 ! neuron fate specification GO:0048665 11 10 0,000 0,0136474 0,0324602 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,0136474 0,03242667 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,0136474 0,0323932 ! thyroid gland development GO:0030878 19 10 0,000 0,0136474 0,03235981 ! synapsis GO:0007129 13 10 0,000 0,0136474 0,03232648 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,0136474 0,03229322 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,0136474 0,03226003 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0136474 0,03222691 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,0136474 0,03219386 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,0136474 0,03216087 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,0136474 0,03212796 ! androgen metabolic process GO:0008209 13 10 0,000 0,0136474 0,0320951 ! phospholipid efflux GO:0033700 16 10 0,000 0,0136474 0,03206232 ! hippocampus development GO:0021766 19 10 0,000 0,0136474 0,0320296 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,0136474 0,03199695 ! blood vessel remodeling GO:0001974 21 10 0,000 0,0136474 0,03196437 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,0136474 0,03193185 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,0136474 0,0318994 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,0136474 0,03186702 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,0136474 0,0318347 ! pathogenesis GO:0009405 13 10 0,000 0,0136474 0,03180244 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0136474 0,03177026 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0136474 0,03173813 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,0136474 0,03170607 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,0136474 0,03167408 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,0136474 0,03164215 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,0136474 0,03161028 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,0136474 0,03157848 ! melanocyte differentiation GO:0030318 15 10 0,000 0,0136474 0,03154675 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,0136474 0,03151507 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0136474 0,03148346 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0136474 0,03145192 ! response to X-ray GO:0010165 16 10 0,000 0,0136474 0,03142043 ! B cell proliferation GO:0042100 14 10 0,000 0,0136474 0,03138901 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,0136474 0,03135765 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0136474 0,03132636 ! forebrain cell migration GO:0021885 17 10 0,000 0,0136474 0,03129513 ! lipid digestion GO:0044241 15 10 0,000 0,0136474 0,03126396 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0136474 0,03123285 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0136474 0,0312018 ! UV protection GO:0009650 14 10 0,000 0,0136474 0,03117082 ! entry into host cell GO:0030260 20 10 0,000 0,0136474 0,03113989 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,0136474 0,03110903 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0136474 0,03107823 ! negative regulation of ossification GO:0030279 19 10 0,000 0,0136474 0,03104749 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,0136474 0,03101681 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,0136474 0,03098619 ! regulation of bone resorption GO:0045124 24 10 0,000 0,0136474 0,03095563 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,0136474 0,03092514 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,0136474 0,0308947 ! regulation of organ growth GO:0046620 11 10 0,000 0,0136474 0,03086432 ! response to dsRNA GO:0043331 18 10 0,000 0,0136474 0,030834 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,0136474 0,03080374 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0136474 0,03077354 ! embryonic axis specification GO:0000578 12 10 0,000 0,0136474 0,0307434 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,0136474 0,03071332 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0136474 0,0306833 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0136474 0,03065333 ! cranial nerve development GO:0021545 12 10 0,000 0,0136474 0,03062343 ! fucose catabolic process GO:0019317 16 10 0,000 0,0136474 0,03059358 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,0136474 0,03056379 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,0136474 0,03053406 ! protein sumoylation GO:0016925 12 10 0,000 0,0136474 0,03050439 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,0136474 0,03047477 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0136474 0,03044521 ! zymogen activation GO:0031638 14 10 0,000 0,0136474 0,03041571 ! salivary gland development GO:0007431 22 10 0,000 0,0136474 0,03038627 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0136474 0,03035688 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,0136474 0,03032755 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0136474 0,03029827 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,0136474 0,03026906 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,0136474 0,0302399 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,0136474 0,03021079 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0136474 0,03018174 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,0136474 0,03015275 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,0136474 0,03012381 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,0136474 0,03009493 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,0136474 0,0300661 ! detection of bacterium GO:0016045 10 10 0,000 0,0136474 0,03003733 ! embryonic gut development GO:0048566 11 10 0,000 0,0136474 0,03000862 ! activation of innate immune response GO:0002218 10 10 0,000 0,0136474 0,02997995 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,0136474 0,02995135 ! developmental induction GO:0031128 13 10 0,000 0,0136474 0,0299228 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,0136474 0,0298943 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,0136474 0,02986585 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,0136474 0,02983746 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,0136474 0,02980913 ! rRNA transcription GO:0009303 17 11 0,000 0,01500228 0,03273742 ! respiratory burst GO:0045730 14 11 0,000 0,01500228 0,03270638 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01500228 0,03267541 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01500228 0,0326445 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01500228 0,03261364 ! virus-host interaction GO:0019048 17 11 0,000 0,01500228 0,03258285 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01500228 0,03255211 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01500228 0,03252143 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01500228 0,03249081 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01500228 0,03246024 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01500228 0,03242973 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01500228 0,03239928 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01500228 0,03236889 ! mating GO:0007618 14 11 0,000 0,01500228 0,03233855 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01500228 0,03230827 ! T cell proliferation GO:0042098 20 11 0,000 0,01500228 0,03227805 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01500228 0,03224788 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01500228 0,03221777 ! bone resorption GO:0045453 16 11 0,000 0,01500228 0,03218772 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01500228 0,03215772 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01500228 0,03212778 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01500228 0,03209789 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01500228 0,03206806 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01500228 0,03203829 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01500228 0,03200857 ! syncytium formation GO:0006949 15 11 0,000 0,01500228 0,0319789 ! plasma membrane organization GO:0007009 18 11 0,000 0,01500228 0,03194929 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01500228 0,03191974 ! focal adhesion formation GO:0048041 24 11 0,000 0,01500228 0,03189024 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01500228 0,03186079 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01500228 0,0318314 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01500228 0,03180206 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01500228 0,03177278 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01500228 0,03174355 ! adult heart development GO:0007512 11 11 0,000 0,01500228 0,03171437 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01500228 0,03168525 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01500228 0,03165618 ! temperature homeostasis GO:0001659 16 11 0,000 0,01500228 0,03162716 ! L-glutamate transport GO:0015813 16 11 0,000 0,01500228 0,0315982 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01500228 0,03156929 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01500228 0,03154044 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01500228 0,03151163 ! stem cell development GO:0048864 29 11 0,000 0,01500228 0,03148288 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01500228 0,03145418 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01500228 0,03142553 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01500228 0,03139694 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01500228 0,0313684 ! vasoconstriction GO:0042310 15 11 0,000 0,01500228 0,03133991 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01500228 0,03131147 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01500228 0,03128308 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01500228 0,03125474 ! ribosome assembly GO:0042255 13 11 0,000 0,01500228 0,03122646 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01500228 0,03119822 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01500228 0,03117004 ! chromatin silencing GO:0006342 19 11 0,000 0,01500228 0,03114191 ! nucleosome positioning GO:0016584 13 11 0,000 0,01500228 0,03111383 ! T cell homeostasis GO:0043029 20 11 0,000 0,01500228 0,0310858 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01500228 0,03105782 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01500228 0,03102989 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01500228 0,03100201 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01500228 0,03097418 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01500228 0,0309464 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01500228 0,03091867 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01500228 0,03089099 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01500228 0,03086336 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01500228 0,03083578 ! male genitalia development GO:0030539 13 11 0,000 0,01500228 0,03080825 ! cholesterol efflux GO:0033344 19 11 0,000 0,01500228 0,03078076 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01500228 0,03075333 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01500228 0,03072594 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01500228 0,03069861 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01500228 0,03067132 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01500228 0,03064408 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01500228 0,03061689 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01500228 0,03058975 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01500228 0,03056265 ! actin filament polymerization GO:0030041 17 11 0,000 0,01500228 0,03053561 ! acrosome reaction GO:0007340 13 11 0,000 0,01500228 0,03050861 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01500228 0,03048166 ! lactation GO:0007595 20 12 0,000 0,01635537 0,03320155 ! reproductive cellular process GO:0048610 14 12 0,000 0,01635537 0,03317227 ! tRNA modification GO:0006400 14 12 0,000 0,01635537 0,03314305 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01635537 0,03311387 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01635537 0,03308475 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01635537 0,03305567 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01635537 0,03302665 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01635537 0,03299768 ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01635537 0,03296876 ! peroxisomal transport GO:0043574 21 12 0,000 0,01635537 0,03293989 ! cartilage condensation GO:0001502 18 12 0,000 0,01635537 0,03291107 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01635537 0,03288231 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01635537 0,03285359 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01635537 0,03282492 ! heart looping GO:0001947 15 12 0,000 0,01635537 0,0327963 ! palate development GO:0060021 15 12 0,000 0,01635537 0,03276773 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01635537 0,03273921 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01635537 0,03271075 ! arginine metabolic process GO:0006525 13 12 0,000 0,01635537 0,03268233 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01635537 0,03265396 ! methionine metabolic process GO:0006555 13 12 0,000 0,01635537 0,03262564 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01635537 0,03259736 ! Golgi organization GO:0007030 18 12 0,000 0,01635537 0,03256914 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01635537 0,03254097 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01635537 0,03251284 ! monoamine transport GO:0015844 13 12 0,000 0,01635537 0,03248476 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01635537 0,03245674 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01635537 0,03242876 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01635537 0,03240082 ! L-amino acid transport GO:0015807 20 12 0,000 0,01635537 0,03237294 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01635537 0,03234511 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01635537 0,03231732 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01635537 0,03228958 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01635537 0,03226188 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01635537 0,03223424 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01635537 0,03220664 ! cerebellum development GO:0021549 13 12 0,000 0,01635537 0,03217909 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01635537 0,03215159 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01635537 0,03212413 ! histone acetylation GO:0016573 23 12 0,000 0,01635537 0,03209672 ! histone methylation GO:0016571 15 12 0,000 0,01635537 0,03206936 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01635537 0,03204204 ! gland morphogenesis GO:0022612 23 12 0,000 0,01635537 0,03201477 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01635537 0,03198755 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01635537 0,03196037 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01635537 0,03193324 ! response to gamma radiation GO:0010332 20 12 0,000 0,01635537 0,03190616 ! intestinal absorption GO:0050892 19 12 0,000 0,01635537 0,03187912 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01635537 0,03185212 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01635537 0,03182518 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01635537 0,03179827 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01635537 0,03177142 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01635537 0,03174461 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01635537 0,03171784 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01635537 0,03169112 ! microspike assembly GO:0030035 23 12 0,000 0,01635537 0,03166444 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01635537 0,03163781 ! response to cold GO:0009409 14 12 0,000 0,01635537 0,03161122 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01770669 0,03419428 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01770669 0,03416559 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01770669 0,03413695 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01770669 0,03410836 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01770669 0,03407982 ! water transport GO:0006833 17 13 0,000 0,01770669 0,03405132 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01770669 0,03402288 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01770669 0,03399448 ! lipid localization GO:0010876 24 13 0,000 0,01770669 0,03396612 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01770669 0,03393782 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01770669 0,03390956 ! organelle fusion GO:0048284 28 13 0,000 0,01770669 0,03388135 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01770669 0,03385319 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01770669 0,03382507 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01770669 0,033797 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01770669 0,03376897 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01770669 0,033741 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01770669 0,03371306 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01770669 0,03368518 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01770669 0,03365734 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01770669 0,03362955 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01770669 0,0336018 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01770669 0,0335741 ! NAD metabolic process GO:0019674 21 13 0,000 0,01770669 0,03354644 ! exocrine system development GO:0035272 27 13 0,000 0,01770669 0,03351883 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01770669 0,03349127 ! bone mineralization GO:0030282 15 13 0,000 0,01770669 0,03346375 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01770669 0,03343627 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01770669 0,03340884 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01770669 0,03338146 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01770669 0,03335412 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01770669 0,03332683 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01770669 0,03329958 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01770669 0,03327237 ! genitalia development GO:0048806 15 13 0,000 0,01770669 0,03324521 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01770669 0,03321809 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01770669 0,03319102 ! cellular pigmentation GO:0033059 24 13 0,000 0,01770669 0,03316399 ! tissue regeneration GO:0042246 21 13 0,000 0,01770669 0,03313701 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01770669 0,03311007 ! cofactor transport GO:0051181 19 13 0,000 0,01770669 0,03308317 ! NADP metabolic process GO:0006739 18 13 0,000 0,01770669 0,03305632 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01770669 0,03302951 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01770669 0,03300274 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01770669 0,03297602 ! gas transport GO:0015669 18 13 0,000 0,01770669 0,03294934 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01770669 0,0329227 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01770669 0,03289611 ! regulation of axon extension GO:0030516 23 13 0,000 0,01770669 0,03286956 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01770669 0,03284305 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01770669 0,03281658 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01770669 0,03279016 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01770669 0,03276378 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01770669 0,03273745 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01770669 0,03271115 ! superoxide anion generation GO:0042554 18 14 0,000 0,01905622 0,03517601 ! neuron maturation GO:0042551 21 14 0,000 0,01905622 0,03514781 ! regulation of S phase GO:0033261 18 14 0,000 0,01905622 0,03511964 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01905622 0,03509152 ! myotube differentiation GO:0014902 21 14 0,000 0,01905622 0,03506345 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01905622 0,03503542 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01905622 0,03500744 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01905622 0,0349795 ! inositol metabolic process GO:0006020 20 14 0,000 0,01905622 0,03495161 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01905622 0,03492376 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01905622 0,03489595 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01905622 0,03486819 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01905622 0,03484047 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01905622 0,0348128 ! response to cAMP GO:0051591 19 14 0,000 0,01905622 0,03478517 ! limbic system development GO:0021761 25 14 0,000 0,01905622 0,03475758 ! startle response GO:0001964 21 14 0,000 0,01905622 0,03473004 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01905622 0,03470254 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01905622 0,03467509 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01905622 0,03464768 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01905622 0,03462031 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01905622 0,03459299 ! glycine metabolic process GO:0006544 22 14 0,000 0,01905622 0,03456571 ! pituitary gland development GO:0021983 23 14 0,000 0,01905622 0,03453847 ! cellular response to starvation GO:0009267 21 14 0,000 0,01905622 0,03451127 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01905622 0,03448412 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01905622 0,03445701 ! regulation of heart rate GO:0002027 23 14 0,000 0,01905622 0,03442994 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01905622 0,03440292 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01905622 0,03437593 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01905622 0,03434899 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01905622 0,03432209 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01905622 0,03429524 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01905622 0,03426842 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01905622 0,03424165 ! axon cargo transport GO:0008088 27 14 0,000 0,01905622 0,03421492 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01905622 0,03418823 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01905622 0,03416159 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01905622 0,03413498 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01905622 0,03410842 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01905622 0,03408189 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01905622 0,03405541 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01905622 0,03402897 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01905622 0,03400257 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01905622 0,03397621 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01905622 0,03394989 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01905622 0,03392362 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01905622 0,03389738 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01905622 0,03387119 ! muscle maintenance GO:0046716 19 14 0,000 0,01905622 0,03384503 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01905622 0,03381892 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01905622 0,03379284 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01905622 0,03376681 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01905622 0,03374081 ! cell killing GO:0001906 20 14 0,000 0,01905622 0,03371486 ! cilium assembly GO:0042384 20 14 0,000 0,01905622 0,03368894 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01905622 0,03366307 ! metencephalon development GO:0022037 19 15 0,000 0,02040398 0,03601624 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02040398 0,03598862 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02040398 0,03596104 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02040398 0,03593351 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02040398 0,03590601 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02040398 0,03587856 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02040398 0,03585115 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02040398 0,03582379 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02040398 0,03579646 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02040398 0,03576918 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02040398 0,03574193 ! adult walking behavior GO:0007628 25 15 0,000 0,02040398 0,03571473 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02040398 0,03568757 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02040398 0,03566046 ! myoblast differentiation GO:0045445 27 15 0,000 0,02040398 0,03563338 ! centrosome cycle GO:0007098 16 15 0,000 0,02040398 0,03560634 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02040398 0,03557935 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02040398 0,03555239 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02040398 0,03552548 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02040398 0,03549861 ! cerebral cortex development GO:0021987 29 15 0,000 0,02040398 0,03547178 ! response to osmotic stress GO:0006970 22 15 0,000 0,02040398 0,03544498 ! vesicle coating GO:0006901 25 15 0,000 0,02040398 0,03541823 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02040398 0,03539152 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02040398 0,03536485 ! peptide secretion GO:0002790 27 15 0,000 0,02040398 0,03533822 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02040398 0,03531163 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02040398 0,03528508 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02040398 0,03525857 ! neuron recognition GO:0008038 22 15 0,000 0,02040398 0,0352321 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02040398 0,03520567 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02040398 0,03517928 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02040398 0,03515293 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02040398 0,03512662 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02040398 0,03510034 ! biomineral formation GO:0031214 18 15 0,000 0,02040398 0,03507411 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02040398 0,03504792 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02040398 0,03502176 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02040398 0,03499564 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02040398 0,03496957 ! organic cation transport GO:0015695 19 15 0,000 0,02040398 0,03494353 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02040398 0,03491753 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02040398 0,03489157 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02040398 0,03486565 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02040398 0,03483976 ! defense response to virus GO:0051607 27 15 0,000 0,02040398 0,03481392 ! peptide hormone processing GO:0016486 19 15 0,000 0,02040398 0,03478811 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02040398 0,03476234 ! protein secretion GO:0009306 27 16 0,000 0,02174997 0,03702807 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02174997 0,03700068 ! hormone secretion GO:0046879 25 16 0,000 0,02174997 0,03697334 ! bone remodeling GO:0046849 24 16 0,000 0,02174997 0,03694603 ! endothelial cell migration GO:0043542 22 16 0,000 0,02174997 0,03691876 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02174997 0,03689154 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02174997 0,03686435 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02174997 0,0368372 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02174997 0,0368101 ! glial cell development GO:0021782 24 16 0,000 0,02174997 0,03678303 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02174997 0,036756 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02174997 0,03672902 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02174997 0,03670207 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02174997 0,03667516 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02174997 0,03664829 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02174997 0,03662147 ! fructose metabolic process GO:0006000 20 16 0,000 0,02174997 0,03659468 ! regulation of protein binding GO:0043393 27 16 0,000 0,02174997 0,03656793 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02174997 0,03654121 ! protein export from nucleus GO:0006611 24 16 0,000 0,02174997 0,03651454 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02174997 0,03648791 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02174997 0,03646131 ! DNA replication initiation GO:0006270 25 16 0,000 0,02174997 0,03643476 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02174997 0,03640824 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02174997 0,03638176 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02174997 0,03635532 ! diencephalon development GO:0021536 25 16 0,000 0,02174997 0,03632892 ! oogenesis GO:0048477 23 16 0,000 0,02174997 0,03630256 ! neural crest cell migration GO:0001755 24 16 0,000 0,02174997 0,03627623 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02174997 0,03624994 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02174997 0,03622369 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02174997 0,03619748 ! steroid catabolic process GO:0006706 22 16 0,000 0,02174997 0,03617131 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02174997 0,03614518 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02174997 0,03611908 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02174997 0,03609302 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02174997 0,036067 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02174997 0,03604101 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02174997 0,03601506 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02174997 0,03598915 ! nerve development GO:0021675 18 16 0,000 0,02174997 0,03596328 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02174997 0,03593744 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02174997 0,03591165 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02309418 0,03810374 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02309418 0,03807642 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02309418 0,03804915 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02309418 0,03802191 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02309418 0,03799471 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02309418 0,03796756 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02309418 0,03794044 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02309418 0,03791335 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02309418 0,03788631 ! signal complex assembly GO:0007172 29 17 0,000 0,02309418 0,03785931 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02309418 0,03783234 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02309418 0,03780542 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02309418 0,03777853 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02309418 0,03775168 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02309418 0,03772486 ! memory GO:0007613 25 17 0,000 0,02309418 0,03769809 ! keratinization GO:0031424 17 17 0,000 0,02309418 0,03767135 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02309418 0,03764466 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02309418 0,037618 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02309418 0,03759137 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02309418 0,03756479 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02309418 0,03753824 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02309418 0,03751173 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02309418 0,03748526 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02309418 0,03745882 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02309418 0,03743242 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02309418 0,03740606 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02309418 0,03737974 ! membrane budding GO:0006900 29 17 0,000 0,02309418 0,03735345 ! heme metabolic process GO:0042168 27 17 0,000 0,02309418 0,0373272 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02309418 0,03730099 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02309418 0,03727481 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02309418 0,03724867 ! body fluid secretion GO:0007589 27 17 0,000 0,02309418 0,03722257 ! stem cell differentiation GO:0048863 36 17 0,000 0,02309418 0,03719651 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02309418 0,03717048 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02309418 0,03714448 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02309418 0,03711853 ! sensory perception of pain GO:0019233 23 17 0,000 0,02309418 0,0370926 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02309418 0,03706672 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02309418 0,03704087 ! synaptogenesis GO:0007416 24 17 0,000 0,02309418 0,03701506 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02309418 0,03698928 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02309418 0,03696354 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02309418 0,03693784 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02309418 0,03691217 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02309418 0,03688653 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02309418 0,03686094 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02309418 0,03683537 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02309418 0,03680985 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02309418 0,03678436 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02309418 0,0367589 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02443662 0,03886876 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02443662 0,0388419 ! positive regulation of translation GO:0045727 28 18 0,000 0,02443662 0,03881507 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02443662 0,03878828 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02443662 0,03876153 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02443662 0,03873482 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02443662 0,03870814 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02443662 0,0386815 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02443662 0,0386549 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02443662 0,03862833 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02443662 0,0386018 ! axis specification GO:0009798 26 18 0,000 0,02443662 0,03857531 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02443662 0,03854885 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02443662 0,03852243 ! pancreas development GO:0031016 26 18 0,000 0,02443662 0,03849604 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02443662 0,0384697 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02443662 0,03844338 ! response to retinoic acid GO:0032526 25 18 0,000 0,02443662 0,03841711 ! pigmentation during development GO:0048066 31 18 0,000 0,02443662 0,03839086 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02443662 0,03836466 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02443662 0,03833849 ! fucose metabolic process GO:0006004 26 18 0,000 0,02443662 0,03831235 ! response to fungus GO:0009620 19 18 0,000 0,02443662 0,03828626 ! peptide cross-linking GO:0018149 31 18 0,000 0,02443662 0,03826019 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02443662 0,03823417 ! heart process GO:0003015 27 18 0,000 0,02443662 0,03820817 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02443662 0,03818222 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02443662 0,0381563 ! visual learning GO:0008542 35 18 0,000 0,02443662 0,03813041 ! somitogenesis GO:0001756 24 18 0,000 0,02443662 0,03810456 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02443662 0,03807874 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02443662 0,03805296 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02443662 0,03802722 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02443662 0,0380015 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02443662 0,03797583 ! vitamin transport GO:0051180 24 18 0,000 0,02443662 0,03795019 ! hormone transport GO:0009914 27 18 0,000 0,02443662 0,03792458 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02443662 0,03789901 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02443662 0,03787347 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02443662 0,03784796 ! cell-cell recognition GO:0009988 20 18 0,000 0,02443662 0,03782249 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02443662 0,03779706 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02443662 0,03777166 ! regulation of glucose import GO:0046324 21 18 0,000 0,02443662 0,03774629 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02443662 0,03772096 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02443662 0,03769566 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02443662 0,03767039 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02577729 0,0397105 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02577729 0,03968392 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02577729 0,03965737 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02577729 0,03963086 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02577729 0,03960439 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02577729 0,03957795 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02577729 0,03955155 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02577729 0,03952518 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02577729 0,03949885 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02577729 0,03947255 ! regeneration GO:0031099 32 19 0,000 0,02577729 0,03944629 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02577729 0,03942006 ! response to alkaloid GO:0043279 32 19 0,000 0,02577729 0,03939387 ! sensory perception of taste GO:0050909 23 19 0,000 0,02577729 0,03936771 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02577729 0,03934159 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02577729 0,0393155 ! peroxisome organization GO:0007031 29 19 0,000 0,02577729 0,03928945 ! digestive system process GO:0022600 30 19 0,000 0,02577729 0,03926343 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02577729 0,03923744 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02577729 0,03921149 ! response to vitamin A GO:0033189 26 19 0,000 0,02577729 0,03918557 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02577729 0,03915969 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02577729 0,03913384 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02577729 0,03910803 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02577729 0,03908225 ! response to starvation GO:0042594 30 19 0,000 0,02577729 0,0390565 ! sex determination GO:0007530 29 19 0,000 0,02577729 0,03903079 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02577729 0,03900511 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02577729 0,03897947 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02577729 0,03895386 ! cytolysis GO:0019835 20 19 0,000 0,02577729 0,03892828 ! renal system process GO:0003014 35 19 0,000 0,02577729 0,03890274 ! vasodilation GO:0042311 33 19 0,000 0,02577729 0,03887723 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02577729 0,03885175 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02577729 0,03882631 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02577729 0,0388009 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02577729 0,03877552 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02577729 0,03875018 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02577729 0,03872487 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02577729 0,03869959 ! sarcomere organization GO:0045214 23 19 0,000 0,02577729 0,03867435 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02577729 0,03864914 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02577729 0,03862396 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02577729 0,03859881 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02577729 0,0385737 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02577729 0,03854862 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02577729 0,03852357 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02577729 0,03849855 ! protein stabilization GO:0050821 26 19 0,000 0,02577729 0,03847357 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0271162 0,04044569 ! iron ion transport GO:0006826 37 20 0,000 0,0271162 0,04041948 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0271162 0,0403933 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0271162 0,04036716 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0271162 0,04034105 ! response to vitamin GO:0033273 29 20 0,000 0,0271162 0,04031497 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0271162 0,04028893 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0271162 0,04026292 ! spinal cord development GO:0021510 31 20 0,000 0,0271162 0,04023694 ! response to ethanol GO:0045471 37 20 0,000 0,0271162 0,040211 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0271162 0,04018509 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0271162 0,04015922 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0271162 0,04013337 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0271162 0,04010756 ! chromosome condensation GO:0030261 31 20 0,000 0,0271162 0,04008179 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0271162 0,04005604 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0271162 0,04003033 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0271162 0,04000466 ! pallium development GO:0021543 38 20 0,000 0,0271162 0,03997901 ! DNA modification GO:0006304 28 20 0,000 0,0271162 0,0399534 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0271162 0,03992782 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0271162 0,03990228 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0271162 0,03987677 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0271162 0,03985129 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0271162 0,03982584 ! collagen catabolic process GO:0030574 25 20 0,000 0,0271162 0,03980042 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0271162 0,03977504 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0271162 0,03974969 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0271162 0,03972437 ! alditol metabolic process GO:0019400 24 20 0,000 0,0271162 0,03969908 ! actin filament-based movement GO:0030048 34 20 0,000 0,0271162 0,03967383 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02845334 0,04160375 ! regulation of cell killing GO:0031341 34 21 0,000 0,02845334 0,04157731 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02845334 0,04155092 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02845334 0,04152455 ! gluconeogenesis GO:0006094 25 21 0,000 0,02845334 0,04149822 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02845334 0,04147192 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02845334 0,04144566 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02845334 0,04141943 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02845334 0,04139323 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02845334 0,04136706 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02845334 0,04134093 ! vesicle docking GO:0048278 27 21 0,000 0,02845334 0,04131483 ! phototransduction GO:0007602 25 21 0,000 0,02845334 0,04128877 ! dendrite development GO:0016358 35 21 0,000 0,02845334 0,04126273 ! visual behavior GO:0007632 39 21 0,000 0,02845334 0,04123673 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02845334 0,04121076 ! ovarian follicle development GO:0001541 30 21 0,000 0,02845334 0,04118483 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02845334 0,04115893 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02845334 0,04113306 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02845334 0,04110722 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02845334 0,04108141 ! cell aging GO:0007569 32 21 0,000 0,02845334 0,04105564 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02845334 0,0410299 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02845334 0,04100419 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02845334 0,04097852 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02845334 0,04095287 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02845334 0,04092726 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02845334 0,04090168 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02845334 0,04087614 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02845334 0,04085062 ! immunoglobulin production GO:0002377 33 21 0,000 0,02845334 0,04082514 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02845334 0,04079968 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02845334 0,04077426 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02845334 0,04074887 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02845334 0,04072352 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02845334 0,04069819 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02845334 0,0406729 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02845334 0,04064764 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02845334 0,0406224 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02845334 0,0405972 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02845334 0,04057204 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02845334 0,0405469 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02845334 0,04052179 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02845334 0,04049672 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02845334 0,04047167 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02978873 0,04234492 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02978873 0,04231876 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02978873 0,04229264 ! viral genome replication GO:0019079 29 22 0,000 0,02978873 0,04226655 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02978873 0,04224049 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02978873 0,04221446 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02978873 0,04218847 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02978873 0,04216251 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02978873 0,04213658 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02978873 0,04211068 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02978873 0,04208481 ! vasculogenesis GO:0001570 33 22 0,000 0,02978873 0,04205898 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02978873 0,04203317 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02978873 0,0420074 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02978873 0,04198166 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02978873 0,04195595 ! lysosome organization GO:0007040 37 22 0,000 0,02978873 0,04193028 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02978873 0,04190463 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02978873 0,04187902 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02978873 0,04185344 ! regulation of behavior GO:0050795 38 22 0,000 0,02978873 0,04182788 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02978873 0,04180236 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02978873 0,04177687 ! membrane depolarization GO:0051899 35 22 0,000 0,02978873 0,04175142 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02978873 0,04172599 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02978873 0,04170059 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02978873 0,04167523 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02978873 0,04164989 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02978873 0,04162459 ! blastocyst development GO:0001824 37 22 0,000 0,02978873 0,04159932 ! neural tube closure GO:0001843 33 22 0,000 0,02978873 0,04157407 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02978873 0,04154886 ! protein tetramerization GO:0051262 39 22 0,000 0,02978873 0,04152368 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03112235 0,04335639 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03112235 0,04333015 ! myelination GO:0042552 35 23 0,000 0,03112235 0,04330394 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03112235 0,04327776 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03112235 0,04325161 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03112235 0,04322549 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03112235 0,0431994 ! vesicle targeting GO:0006903 32 23 0,000 0,03112235 0,04317335 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03112235 0,04314732 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03112235 0,04312133 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03112235 0,04309537 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03112235 0,04306944 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03112235 0,04304354 ! interaction with host GO:0051701 37 23 0,000 0,03112235 0,04301767 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03112235 0,04299184 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03112235 0,04296603 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03112235 0,04294026 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03112235 0,04291451 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03112235 0,0428888 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03112235 0,04286312 ! cell fate determination GO:0001709 45 23 0,000 0,03112235 0,04283747 ! pentose metabolic process GO:0019321 31 23 0,000 0,03112235 0,04281185 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03112235 0,04278626 ! spermatid development GO:0007286 33 23 0,000 0,03112235 0,0427607 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03112235 0,04273517 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03112235 0,04270967 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03112235 0,0426842 ! telomere organization GO:0032200 32 23 0,000 0,03112235 0,04265877 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03112235 0,04263336 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03112235 0,04260798 ! regulation of amine transport GO:0051952 38 23 0,000 0,03112235 0,04258263 ! liver development GO:0001889 40 23 0,000 0,03112235 0,04255732 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03245422 0,04435217 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03245422 0,04432583 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03245422 0,04429953 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03245422 0,04427325 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03245422 0,04424701 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03245422 0,04422079 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03245422 0,04419461 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03245422 0,04416846 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03245422 0,04414234 ! sperm motility GO:0030317 27 24 0,000 0,03245422 0,04411625 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03245422 0,0440902 ! vacuole organization GO:0007033 39 24 0,000 0,03245422 0,04406417 ! receptor metabolic process GO:0043112 37 24 0,000 0,03245422 0,04403817 ! neural crest cell development GO:0014032 39 24 0,000 0,03245422 0,04401221 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03245422 0,04398627 ! primary neural tube formation GO:0014020 35 24 0,000 0,03245422 0,04396037 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03245422 0,04393449 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03245422 0,04390865 ! base-excision repair GO:0006284 31 24 0,000 0,03245422 0,04388283 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03245422 0,04385705 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03245422 0,0438313 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03245422 0,04380558 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03245422 0,04377988 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03245422 0,04375422 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03245422 0,04372859 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03245422 0,04370299 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03378433 0,0454675 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03378433 0,04544091 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03378433 0,04541435 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03378433 0,04538783 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03378433 0,04536133 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03378433 0,04533487 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03378433 0,04530843 ! peptide transport GO:0015833 43 25 0,000 0,03378433 0,04528203 ! male gonad development GO:0008584 33 25 0,000 0,03378433 0,04525566 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03378433 0,04522931 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03378433 0,045203 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03378433 0,04517672 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03378433 0,04515047 ! phospholipid transport GO:0015914 35 25 0,000 0,03378433 0,04512425 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03378433 0,04509806 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03378433 0,0450719 ! detection of light stimulus GO:0009583 30 25 0,000 0,03378433 0,04504577 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03378433 0,04501968 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03378433 0,04499361 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03378433 0,04496757 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03378433 0,04494156 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03511269 0,04668161 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03511269 0,04665464 ! translational initiation GO:0006413 43 26 0,000 0,03511269 0,04662771 ! regulation of pH GO:0006885 36 26 0,000 0,03511269 0,0466008 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03511269 0,04657393 ! circadian rhythm GO:0007623 42 26 0,000 0,03511269 0,04654708 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03511269 0,04652027 ! post-embryonic development GO:0009791 42 26 0,000 0,03511269 0,04649349 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03511269 0,04646674 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03511269 0,04644002 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03511269 0,04641333 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03511269 0,04638667 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03511269 0,04636004 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03511269 0,04633344 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03511269 0,04630687 ! regulation of coagulation GO:0050818 39 26 0,000 0,03511269 0,04628034 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0364393 0,04800137 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0364393 0,04797389 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0364393 0,04794645 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0364393 0,04791903 ! membrane docking GO:0022406 39 27 0,000 0,0364393 0,04789165 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0364393 0,0478643 ! catechol metabolic process GO:0009712 43 27 0,000 0,0364393 0,04783698 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0364393 0,04780969 ! acute-phase response GO:0006953 42 27 0,000 0,0364393 0,04778243 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0364393 0,04775521 ! myofibril assembly GO:0030239 36 27 0,000 0,0364393 0,04772801 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0364393 0,04770085 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0364393 0,04767371 ! natural killer cell activation GO:0030101 35 27 0,000 0,0364393 0,04764661 ! lipid oxidation GO:0034440 38 27 0,000 0,0364393 0,04761954 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0364393 0,0475925 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0364393 0,04756549 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0364393 0,04753851 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0364393 0,04751156 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0364393 0,04748464 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0364393 0,04745775 ! gene silencing GO:0016458 41 27 0,000 0,0364393 0,04743089 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03776416 0,04912759 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03776416 0,04909981 ! phenol metabolic process GO:0018958 44 28 0,000 0,03776416 0,04907207 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03776416 0,04904437 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03776416 0,04901669 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03776416 0,04898904 ! cell junction assembly GO:0034329 56 28 0,000 0,03776416 0,04896143 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03776416 0,04893384 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03776416 0,04890629 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03776416 0,04887877 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03776416 0,04885128 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03776416 0,04882382 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03776416 0,04879639 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03776416 0,04876899 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03776416 0,04874162 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03776416 0,04871429 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03776416 0,04868698 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03776416 0,0486597 ! mesoderm formation GO:0001707 46 28 0,000 0,03776416 0,04863246 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03776416 0,04860524 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03776416 0,04857806 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03776416 0,04855091 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03776416 0,04852378 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03776416 0,04849669 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03776416 0,04846963 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03776416 0,04844259 ! neural tube formation GO:0001841 41 28 0,000 0,03776416 0,04841559 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03776416 0,04838862 ! placenta development GO:0001890 37 28 0,000 0,03776416 0,04836168 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03908728 0,05002823 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03908728 0,05000041 ! ovulation cycle process GO:0022602 41 29 0,000 0,03908728 0,04997262 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03908728 0,04994485 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03908728 0,04991712 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03908728 0,04988942 ! mismatch repair GO:0006298 34 29 0,000 0,03908728 0,04986175 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03908728 0,04983411 ! muscle cell development GO:0055001 38 29 0,000 0,03908728 0,0498065 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03908728 0,04977892 ! telencephalon development GO:0021537 52 29 0,000 0,03908728 0,04975138 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03908728 0,04972386 ! eye morphogenesis GO:0048592 51 29 0,000 0,03908728 0,04969637 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03908728 0,04966892 ! tissue homeostasis GO:0001894 42 29 0,000 0,03908728 0,04964149 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04040865 0,05129133 ! collagen metabolic process GO:0032963 40 30 0,000 0,04040865 0,05126304 ! organic anion transport GO:0015711 51 30 0,000 0,04040865 0,05123478 ! cholesterol transport GO:0030301 46 30 0,000 0,04040865 0,05120655 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04040865 0,05117835 ! spliceosome assembly GO:0000245 49 30 0,000 0,04040865 0,05115019 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04040865 0,05112205 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04040865 0,05109395 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04040865 0,05106587 ! ovulation cycle GO:0042698 43 30 0,000 0,04040865 0,05103783 ! hindbrain development GO:0030902 45 30 0,000 0,04040865 0,05100982 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04040865 0,05098184 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04040865 0,05095389 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04040865 0,05092597 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04040865 0,05089808 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04040865 0,05087022 ! response to heat GO:0009408 41 30 0,000 0,04040865 0,05084239 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04040865 0,05081459 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04040865 0,05078683 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04172828 0,05241674 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04172828 0,05238812 ! mammary gland development GO:0030879 57 31 0,000 0,04172828 0,05235954 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04172828 0,05233099 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04172828 0,05230248 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04172828 0,05227399 ! odontogenesis GO:0042476 50 31 0,000 0,04172828 0,05224553 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04172828 0,05221711 ! segmentation GO:0035282 41 31 0,000 0,04172828 0,05218871 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04172828 0,05216035 ! metanephros development GO:0001656 58 31 0,000 0,04172828 0,05213202 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04172828 0,05210371 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04172828 0,05207544 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04172828 0,0520472 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04172828 0,05201899 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04172828 0,05199081 ! RNA modification GO:0009451 40 31 0,000 0,04172828 0,05196267 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04304617 0,05357478 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04304617 0,0535458 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,04304617 0,05351686 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,04304617 0,05348795 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,04304617 0,05345907 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04304617 0,05343022 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04304617 0,0534014 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04304617 0,05337261 ! regulation of protein stability GO:0031647 48 32 0,000 0,04304617 0,05334385 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04304617 0,05331513 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04304617 0,05328643 ! cytokine production GO:0001816 44 32 0,000 0,04304617 0,05325777 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04304617 0,05322914 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04304617 0,05320053 ! vesicle localization GO:0051648 47 32 0,000 0,04304617 0,05317196 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04436232 0,0547683 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04436232 0,05473892 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04436232 0,05470957 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04436232 0,05468025 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04436232 0,05465096 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04436232 0,05462171 ! ear morphogenesis GO:0042471 42 33 0,000 0,04436232 0,05459248 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04436232 0,05456329 ! cell junction organization GO:0034330 63 33 0,000 0,04436232 0,05453412 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04436232 0,05450499 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04436232 0,05447589 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04436232 0,05444682 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04436232 0,05441779 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04436232 0,05438878 ! female gonad development GO:0008585 49 33 0,000 0,04436232 0,0543598 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04436232 0,05433086 ! lipid homeostasis GO:0055088 55 33 0,000 0,04436232 0,05430194 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04436232 0,05427306 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04436232 0,0542442 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04436232 0,05421538 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04436232 0,05418659 ! cytokinesis GO:0000910 52 33 0,000 0,04436232 0,05415783 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04436232 0,0541291 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04567674 0,05570335 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04567674 0,05567383 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04567674 0,05564434 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04567674 0,05561488 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04567674 0,05558546 ! feeding behavior GO:0007631 45 34 0,000 0,04567674 0,05555606 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04567674 0,0555267 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04567674 0,05549736 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04567674 0,05546806 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04567674 0,05543879 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04567674 0,05540955 ! neuron migration GO:0001764 46 34 0,000 0,04567674 0,05538034 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04567674 0,05535117 ! female gamete generation GO:0007292 43 34 0,000 0,04567674 0,05532202 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04567674 0,0552929 ! polyol metabolic process GO:0019751 44 34 0,000 0,04567674 0,05526381 ! aerobic respiration GO:0009060 47 34 0,000 0,04567674 0,05523476 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04567674 0,05520573 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,04567674 0,05517674 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04567674 0,05514778 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04698943 0,05670288 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,04698943 0,05667315 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04698943 0,05664344 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04698943 0,05661377 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04698943 0,05658413 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04698943 0,05655452 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04698943 0,05652494 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,04698943 0,0564954 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04698943 0,05646588 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04698943 0,05643639 ! pigment metabolic process GO:0042440 61 35 0,000 0,04698943 0,05640694 ! protein homooligomerization GO:0051260 52 35 0,000 0,04698943 0,05637751 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04830039 0,05792017 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04830039 0,05788999 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04830039 0,05785984 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04830039 0,05782972 ! negative regulation of binding GO:0051100 58 36 0,000 0,04830039 0,05779963 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04830039 0,05776957 ! tissue remodeling GO:0048771 62 36 0,000 0,04830039 0,05773955 ! neural tube development GO:0021915 50 36 0,000 0,04830039 0,05770955 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04830039 0,05767959 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04830039 0,05764966 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04830039 0,05761976 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04830039 0,05758989 ! glucan metabolic process GO:0044042 49 36 0,000 0,04830039 0,05756005 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04960962 0,05908965 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04960962 0,05905907 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04960962 0,05902851 ! learning GO:0007612 67 37 0,000 0,04960962 0,05899799 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04960962 0,0589675 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04960962 0,05893704 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04960962 0,05890662 ! amino acid activation GO:0043038 52 37 0,000 0,04960962 0,05887622 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04960962 0,05884586 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05091712 0,06036565 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,05091712 0,06033455 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05091712 0,06030349 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05091712 0,06027245 ! phagocytosis GO:0006909 60 38 0,000 0,05091712 0,06024145 ! pigmentation GO:0043473 74 38 0,000 0,05091712 0,06021047 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05091712 0,06017953 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,05222289 0,06169114 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05222289 0,06165948 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05222289 0,06162784 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,05222289 0,06159623 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05222289 0,06156466 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,05222289 0,06153312 ! male sex differentiation GO:0046661 53 39 0,000 0,05222289 0,06150162 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05222289 0,06147014 ! chromatin remodeling GO:0006338 68 39 0,000 0,05222289 0,0614387 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05222289 0,06140729 ! JNK cascade GO:0007254 54 39 0,000 0,05222289 0,06137591 ! cell growth GO:0016049 61 39 0,000 0,05222289 0,06134456 ! synapse organization GO:0050808 55 39 0,000 0,05222289 0,06131325 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,05352695 0,06281224 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,05352695 0,06278021 ! regulation of tube size GO:0035150 60 40 0,000 0,05352695 0,06274821 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,05352695 0,06271624 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,05352695 0,06268431 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,05352695 0,06265241 ! peptide metabolic process GO:0006518 56 40 0,000 0,05352695 0,06262054 ! inner ear development GO:0048839 57 40 0,000 0,05352695 0,06258871 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,05352695 0,0625569 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,05352695 0,06252513 ! B cell differentiation GO:0030183 62 40 0,000 0,05352695 0,06249339 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,05352695 0,06246169 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,05352695 0,06243001 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,05352695 0,06239837 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,05482929 0,06388417 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05482929 0,06385183 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05482929 0,06381951 ! glucose transport GO:0015758 52 41 0,000 0,05482929 0,06378723 ! endosome transport GO:0016197 71 41 0,000 0,05482929 0,06375499 ! striated muscle contraction GO:0006941 62 41 0,000 0,05482929 0,06372277 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05482929 0,06369059 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05482929 0,06365844 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05482929 0,06362632 ! biopolymer methylation GO:0043414 62 41 0,000 0,05482929 0,06359423 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,05482929 0,06356218 ! mitochondrial transport GO:0006839 60 42 0,000 0,05612991 0,06503717 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,05612991 0,06500442 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,05612991 0,06497171 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05612991 0,06493903 ! cellular component disassembly GO:0022411 64 42 0,000 0,05612991 0,06490638 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,05612991 0,06487376 ! hexose transport GO:0008645 54 42 0,000 0,05612991 0,06484118 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05612991 0,06480863 ! excretion GO:0007588 63 42 0,000 0,05612991 0,06477611 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05612991 0,06474362 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05612991 0,06471117 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05612991 0,06467875 ! regulation of cell shape GO:0008360 78 42 0,000 0,05612991 0,06464636 ! positive regulation of binding GO:0051099 59 43 0,000 0,05742881 0,06610924 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05742881 0,06607617 ! leukocyte migration GO:0050900 60 43 0,000 0,05742881 0,06604313 ! neuromuscular process GO:0050905 79 43 0,000 0,05742881 0,06601013 ! activation of caspase activity GO:0006919 65 43 0,000 0,05742881 0,06597715 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05742881 0,06594422 ! tRNA processing GO:0008033 49 43 0,000 0,05742881 0,06591131 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05742881 0,06587844 ! vesicle organization GO:0016050 79 43 0,000 0,05742881 0,0658456 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05742881 0,06581279 ! methylation GO:0032259 64 43 0,000 0,05742881 0,06578001 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,058726 0,06723236 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,058726 0,06719891 ! glycolysis GO:0006096 53 44 0,000 0,058726 0,06716549 ! regulation of action potential GO:0001508 71 44 0,000 0,058726 0,06713211 ! regulation of ion transport GO:0043269 57 44 0,000 0,058726 0,06709876 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,058726 0,06706544 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,058726 0,06703216 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,058726 0,06699891 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,058726 0,06696569 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,058726 0,06693251 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,058726 0,06689936 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,058726 0,06686624 ! RNA catabolic process GO:0006401 64 45 0,000 0,06002148 0,06830747 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06002148 0,06827369 ! regulation of translational initiation GO:0006446 64 45 0,000 0,06002148 0,06823994 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06002148 0,06820623 ! cell recognition GO:0008037 58 45 0,000 0,06002148 0,06817255 ! cell maturation GO:0048469 60 45 0,000 0,06002148 0,0681389 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06002148 0,06810528 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,06131525 0,06953899 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,06131525 0,06950472 ! cell redox homeostasis GO:0045454 63 46 0,000 0,06131525 0,06947048 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,06131525 0,06943628 ! regulation of ossification GO:0030278 71 46 0,000 0,06131525 0,06940211 ! histone modification GO:0016570 68 46 0,000 0,06131525 0,06936797 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,06131525 0,06933386 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,06260732 0,07076011 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,06260732 0,07072536 ! endocrine system development GO:0035270 83 47 0,000 0,06260732 0,07069064 ! covalent chromatin modification GO:0016569 75 47 0,000 0,06260732 0,07065595 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,06260732 0,0706213 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,06260732 0,07058668 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,06260732 0,0705521 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,06260732 0,07051755 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,06260732 0,07048303 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,06260732 0,07044855 ! chloride transport GO:0006821 67 48 0,000 0,06389768 0,07186536 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,06389768 0,07183023 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,06389768 0,07179514 ! response to temperature stimulus GO:0009266 62 48 0,000 0,06389768 0,07176009 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,06389768 0,07172506 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,06389768 0,07169008 ! gastrulation GO:0007369 73 48 0,000 0,06389768 0,07165512 ! heart morphogenesis GO:0003007 65 48 0,000 0,06389768 0,0716202 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,06389768 0,07158532 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,06389768 0,07155046 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,06389768 0,07151565 ! regulation of endocytosis GO:0030100 63 48 0,000 0,06389768 0,07148086 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,06389768 0,07144611 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,06389768 0,0714114 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,06518633 0,07281621 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,06518633 0,07278086 ! sensory perception of smell GO:0007608 61 49 0,000 0,06518633 0,07274554 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,06518633 0,07271027 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06518633 0,07267502 ! RNA elongation GO:0006354 62 49 0,000 0,06518633 0,07263981 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,06518633 0,07260463 ! germ cell development GO:0007281 68 49 0,000 0,06518633 0,07256949 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,06518633 0,07253438 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,06518633 0,07249931 ! maintenance of location GO:0051235 84 49 0,000 0,06518633 0,07246427 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06647329 0,07385921 ! ear development GO:0043583 72 50 0,000 0,06647329 0,07382355 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,06647329 0,07378792 ! membrane fusion GO:0006944 80 50 0,000 0,06647329 0,07375232 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06647329 0,07371676 ! lipid modification GO:0030258 73 50 0,000 0,06647329 0,07368124 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06647329 0,07364575 ! proton transport GO:0015992 75 50 0,000 0,06647329 0,07361029 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06647329 0,07357486 ! positive regulation of secretion GO:0051047 71 51 0,000 0,06775855 0,07496136 ! hydrogen transport GO:0006818 77 51 0,000 0,06775855 0,07492532 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,06775855 0,07488932 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,06775855 0,07485335 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,06775855 0,07481741 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,06775855 0,07478151 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,06775855 0,07474564 ! adult behavior GO:0030534 80 51 0,000 0,06775855 0,07470981 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,06775855 0,07467401 ! transition metal ion transport GO:0000041 74 52 0,000 0,06904211 0,07605214 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06904211 0,07601573 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06904211 0,07597936 ! aging GO:0007568 79 52 0,000 0,06904211 0,07594302 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,06904211 0,07590672 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06904211 0,07587045 ! establishment of organelle localization GO:0051656 85 52 0,000 0,06904211 0,07583422 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,07032398 0,07720533 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,07032398 0,07716849 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,07032398 0,07713169 ! kidney development GO:0001822 90 53 0,000 0,07032398 0,07709493 ! single fertilization GO:0007338 59 53 0,000 0,07032398 0,0770582 ! cell projection assembly GO:0030031 76 53 0,000 0,07032398 0,07702151 ! amino acid transport GO:0006865 84 54 0,000 0,07160416 0,07838628 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,07160416 0,07834899 ! regulation of mitosis GO:0007088 84 54 0,000 0,07160416 0,07831173 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,07160416 0,07827451 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,07160416 0,07823733 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,07160416 0,07820018 ! DNA catabolic process GO:0006308 67 54 0,000 0,07160416 0,07816306 ! detection of external stimulus GO:0009581 66 54 0,000 0,07160416 0,07812598 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,07160416 0,07808894 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,07160416 0,07805193 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,07160416 0,07801496 ! exocytosis GO:0006887 74 55 0,000 0,07288265 0,07937031 ! mesoderm development GO:0007498 76 55 0,000 0,07288265 0,07933275 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,07288265 0,07929522 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,07288265 0,07925773 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,07415945 0,0806081 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,07415945 0,08057002 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,07415945 0,08053198 ! carbohydrate transport GO:0008643 74 57 0,000 0,07543457 0,08187801 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,07543457 0,08183939 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,07543457 0,0818008 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,07543457 0,08176226 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,07543457 0,08172374 ! camera-type eye development GO:0043010 88 57 0,000 0,07543457 0,08168527 ! secondary metabolic process GO:0019748 84 57 0,000 0,07543457 0,08164683 ! gonad development GO:0008406 79 57 0,000 0,07543457 0,08160842 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,076708 0,08294706 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,076708 0,08290808 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,076708 0,08286914 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,07797975 0,08420349 ! activation of MAPK activity GO:0000187 84 59 0,000 0,07797975 0,08416398 ! actin filament organization GO:0007015 95 59 0,000 0,07797975 0,0841245 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07797975 0,08408506 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,07797975 0,08404566 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,07924983 0,08537452 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,07924983 0,08533455 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,07924983 0,08529462 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,07924983 0,08525472 ! regulation of heart contraction GO:0008016 91 60 0,000 0,07924983 0,08521487 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,07924983 0,08517505 ! fertilization GO:0009566 68 60 0,000 0,07924983 0,08513526 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,07924983 0,08509552 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,08051822 0,08641713 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,08051822 0,08637682 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,08051822 0,08633656 ! urogenital system development GO:0001655 101 61 0,000 0,08051822 0,08629632 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,08051822 0,08625613 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,08051822 0,08621597 ! extracellular matrix organization GO:0030198 103 61 0,000 0,08051822 0,08617585 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,08051822 0,08613577 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,08178494 0,0874502 ! neurotransmitter transport GO:0006836 81 62 0,000 0,08178494 0,08740956 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,08178494 0,08736896 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,08178494 0,0873284 ! organelle localization GO:0051640 96 62 0,000 0,08178494 0,08728788 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,08304999 0,08859693 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,08304999 0,08855586 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,08304999 0,08851482 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,08304999 0,08847382 ! regulation of lipase activity GO:0060191 109 63 0,000 0,08304999 0,08843286 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,08431337 0,08973658 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,08431337 0,08969508 ! hexose catabolic process GO:0019320 82 64 0,000 0,08431337 0,08965361 ! adaptive immune response GO:0002250 94 64 0,000 0,08431337 0,08961218 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,08557508 0,09091117 ! B cell activation GO:0042113 104 65 0,000 0,08557508 0,0908692 ! defense response to bacterium GO:0042742 73 65 0,000 0,08557508 0,09082727 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,08557508 0,09078537 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,08557508 0,09074352 ! activation of immune response GO:0002253 83 65 0,000 0,08557508 0,0907017 ! protein oligomerization GO:0051259 100 65 0,000 0,08557508 0,09065992 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,08683513 0,09195248 ! antigen processing and presentation GO:0019882 96 66 0,000 0,08683513 0,09191017 ! axon guidance GO:0007411 99 66 0,000 0,08683513 0,09186789 ! regulation of immune effector process GO:0002697 101 66 0,000 0,08683513 0,09182565 ! acute inflammatory response GO:0002526 92 68 0,000 0,08935023 0,09444188 ! learning or memory GO:0007611 123 68 0,000 0,08935023 0,0943985 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,08935023 0,09435515 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,08935023 0,09431185 ! rhythmic process GO:0048511 105 68 0,000 0,08935023 0,09426859 ! inorganic anion transport GO:0015698 93 68 0,000 0,08935023 0,09422537 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,09060529 0,09550511 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,09060529 0,09546136 ! response to drug GO:0042493 108 69 0,000 0,09060529 0,09541766 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,09185869 0,09669336 ! humoral immune response GO:0006959 86 70 0,000 0,09185869 0,09664912 ! eye development GO:0001654 111 70 0,000 0,09185869 0,09660493 ! amine transport GO:0015837 101 70 0,000 0,09185869 0,09656078 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,09185869 0,09651667 ! regulation of catabolic process GO:0009894 106 70 0,000 0,09185869 0,09647259 ! muscle cell differentiation GO:0042692 104 71 0,000 0,09311043 0,09774258 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,09311043 0,09769799 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,09311043 0,09765344 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,09311043 0,09760893 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,09311043 0,09756446 ! response to hypoxia GO:0001666 132 72 0,000 0,09436052 0,09882933 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,09436052 0,09878435 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,09436052 0,0987394 ! negative regulation of transport GO:0051051 116 73 0,000 0,09560897 0,10000028 ! regulation of blood pressure GO:0008217 107 73 0,000 0,09560897 0,09995483 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,09560897 0,09990941 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,09560897 0,09986404 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,09685576 0,1011204 ! response to oxygen levels GO:0070482 137 74 0,000 0,09685576 0,10107452 ! digestion GO:0007586 97 74 0,000 0,09685576 0,10102868 ! protein import into nucleus GO:0006606 118 74 0,000 0,09685576 0,10098288 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,09685576 0,10093713 ! blood coagulation GO:0007596 116 75 0,000 0,0981009 0,10218844 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,0981009 0,10214218 ! nuclear import GO:0051170 121 75 0,000 0,0981009 0,10209596 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,0981009 0,10204978 ! amine biosynthetic process GO:0009309 97 76 0,000 0,0993444 0,10329662 ! tRNA metabolic process GO:0006399 95 76 0,000 0,0993444 0,10324994 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,0993444 0,1032033 ! regulation of protein transport GO:0051223 114 76 0,000 0,0993444 0,10315671 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,10058625 0,10439909 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,10058625 0,104352 ! regulation of DNA binding GO:0051101 119 77 0,000 0,10058625 0,10430495 ! gland development GO:0048732 148 77 0,000 0,10058625 0,10425795 ! sex differentiation GO:0007548 105 77 0,000 0,10058625 0,10421098 ! protein ubiquitination GO:0016567 125 77 0,000 0,10058625 0,10416406 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,10058625 0,10411718 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,10058625 0,10407035 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,10058625 0,10402355 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,10182647 0,10525882 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,10182647 0,10521154 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,10306504 0,10644347 ! cellular respiration GO:0045333 107 79 0,000 0,10306504 0,10639569 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,10306504 0,10634796 ! T cell activation GO:0042110 134 79 0,000 0,10306504 0,10630027 ! regulation of lyase activity GO:0051339 133 79 0,000 0,10306504 0,10625262 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,10306504 0,10620502 ! chromatin assembly GO:0031497 102 80 0,000 0,10430198 0,10743151 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,10430198 0,10738342 ! protein localization in nucleus GO:0034504 133 80 0,000 0,10430198 0,10733537 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,10553729 0,10855803 ! hemostasis GO:0007599 125 81 0,000 0,10553729 0,1085095 ! mRNA transport GO:0051028 121 81 0,000 0,10553729 0,10846102 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,10553729 0,10841258 ! regulation of neurological system process GO:0031644 122 81 0,000 0,10553729 0,10836418 ! vitamin metabolic process GO:0006766 103 81 0,000 0,10553729 0,10831582 ! ossification GO:0001503 134 82 0,000 0,10677096 0,1095331 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,10677096 0,10948426 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,108003 0,11069826 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,108003 0,11064895 ! regulation of defense response GO:0031347 117 84 0,000 0,10923341 0,11185968 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,10923341 0,1118099 ! sterol metabolic process GO:0016125 120 84 0,000 0,10923341 0,11176016 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,11046219 0,11296712 ! rRNA metabolic process GO:0016072 107 85 0,000 0,11046219 0,11291691 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,11046219 0,11286674 ! transcription initiation GO:0006352 118 85 0,000 0,11046219 0,11281663 ! regulation of protein localization GO:0032880 132 85 0,000 0,11046219 0,11276655 ! regulation of membrane potential GO:0042391 128 85 0,000 0,11046219 0,11271652 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,11168935 0,11391819 ! nucleosome organization GO:0034728 114 87 0,000 0,11291489 0,11511713 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,11291489 0,11506613 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,11291489 0,11501517 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,11291489 0,11496425 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,11291489 0,11491338 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,11291489 0,11486256 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,11413881 0,11605626 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,11413881 0,11600497 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,11413881 0,11595374 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,11413881 0,11590254 ! reproductive developmental process GO:0003006 127 89 0,000 0,11536111 0,11709203 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,11536111 0,11704038 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,11536111 0,11698878 ! regulation of T cell activation GO:0050863 128 89 0,000 0,11536111 0,11693722 ! leukocyte differentiation GO:0002521 143 90 0,000 0,11658179 0,11812252 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,11658179 0,1180705 ! hormone metabolic process GO:0042445 121 90 0,000 0,11658179 0,11801854 ! ATP metabolic process GO:0046034 137 91 0,000 0,11780086 0,11920016 ! response to virus GO:0009615 122 91 0,000 0,11780086 0,11914775 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,11901831 0,12032621 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,11901831 0,12027334 ! positive regulation of immune response GO:0050778 121 92 0,000 0,11901831 0,12022052 ! sulfur metabolic process GO:0006790 118 92 0,000 0,11901831 0,12016774 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,12023416 0,12134207 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,12023416 0,12128885 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,12023416 0,12123567 ! electron transport chain GO:0022900 123 94 0,000 0,1214484 0,12240636 ! response to oxidative stress GO:0006979 141 94 0,000 0,1214484 0,12235274 ! regulation of binding GO:0051098 151 95 0,000 0,12266103 0,1235203 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,12387206 0,12468522 ! in utero embryonic development GO:0001701 147 96 0,000 0,12387206 0,12463068 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,12387206 0,12457618 ! protein maturation GO:0051604 129 96 0,000 0,12387206 0,12452174 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,12508148 0,12568257 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,12508148 0,12562769 ! calcium ion transport GO:0006816 167 99 0,000 0,12749554 0,12799639 ! extracellular structure organization GO:0043062 156 99 0,000 0,12749554 0,12794055 ! protein import GO:0017038 156 99 0,000 0,12749554 0,12788475 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,12870017 0,12903678 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,12870017 0,12898056 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,12870017 0,12892438 ! divalent metal ion transport GO:0070838 171 100 0,000 0,12870017 0,12886826 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,12870017 0,12881218 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,12870017 0,12875615 ! protein localization in organelle GO:0033365 161 100 0,000 0,12870017 0,12870017