pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/9024-10-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 4,000 1,666E-09 3,953E-06 ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 2,000 3,036E-08 3,602E-05 ! nucleoside diphosphate metabolic process GO:0009132 9 8 2,000 4,854E-08 3,84E-05 ! deoxyribonucleotide metabolic process GO:0009262 29 22 2,000 1,323E-06 7,849E-04 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 9,59E-06 4,552E-03 ! induction of apoptosis by intracellular signals GO:0008629 78 42 2,000 9,737E-06 3,851E-03 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 2,000 1,122E-05 3,803E-03 ! response to UV GO:0009411 79 47 2,000 1,371E-05 4,066E-03 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 1,438E-05 3,791E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,012E-05 4,773E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 2,68E-05 5,782E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 2,68E-05 5,301E-03 ! regulation of focal adhesion formation GO:0051893 17 8 1,000 2,68E-05 4,893E-03 ! negative regulation of protein kinase activity GO:0006469 110 62 2,000 3,167E-05 5,368E-03 ! negative regulation of kinase activity GO:0033673 112 63 2,000 3,323E-05 5,257E-03 ! negative regulation of transferase activity GO:0051348 117 66 2,000 3,822E-05 5,668E-03 ! protein oligomerization GO:0051259 109 66 2,000 3,822E-05 5,335E-03 ! positive regulation of B cell proliferation GO:0030890 14 10 1,000 4,303E-05 5,672E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 4,303E-05 5,374E-03 ! regulation of stress fiber formation GO:0051492 24 10 1,000 4,303E-05 5,105E-03 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 4,303E-05 4,862E-03 ! establishment of cell polarity GO:0030010 12 10 1,000 4,303E-05 4,641E-03 ! regulation of phosphatase activity GO:0010921 23 11 1,000 5,256E-05 5,422E-03 ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 5,256E-05 5,197E-03 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 6,303E-05 5,983E-03 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 6,303E-05 5,753E-03 ! regulation of B cell proliferation GO:0030888 24 13 1,000 7,444E-05 6,543E-03 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 8,68E-05 7,356E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 8,68E-05 7,103E-03 ! interphase of mitotic cell cycle GO:0051329 166 87 2,000 8,734E-05 6,909E-03 ! interphase GO:0051325 169 89 2,000 9,346E-05 7,154E-03 ! skin development GO:0043588 28 15 1,000 1,001E-04 7,423E-03 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 1,001E-04 7,198E-03 ! positive regulation of cell growth GO:0030307 22 16 1,000 1,143E-04 7,979E-03 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 1,295E-04 8,779E-03 ! cellular response to unfolded protein GO:0034620 24 18 1,000 1,456E-04 9,597E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 38 18 1,000 1,456E-04 9,337E-03 ! positive regulation of cell size GO:0045793 26 19 1,000 1,626E-04 0,01015496 ! negative regulation of translation GO:0017148 28 20 1,000 1,806E-04 0,01098735 ! positive regulation of fibroblast proliferation GO:0048146 30 21 1,000 1,995E-04 0,01183317 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 1,000 1,995E-04 0,01154456 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 1,995E-04 0,01126969 ! cellular response to extracellular stimulus GO:0031668 37 23 1,000 2,4E-04 0,01324555 ! positive regulation of B cell activation GO:0050871 36 23 1,000 2,4E-04 0,01294451 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 2,617E-04 0,01379916 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 2,617E-04 0,01349917 ! regulation of fibroblast proliferation GO:0048145 39 25 1,000 2,843E-04 0,01435217 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 2,843E-04 0,01405316 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of phosphorylation GO:0042326 46 25 1,000 2,843E-04 0,01376636 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 3,078E-04 0,01460648 ! fat cell differentiation GO:0045444 41 27 1,000 3,322E-04 0,01545636 ! negative regulation of phosphorus metabolic process GO:0010563 51 27 1,000 3,322E-04 0,01515912 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 56 28 1,000 3,575E-04 0,01600753 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 3,838E-04 0,0168647 ! spindle organization GO:0007051 39 33 1,000 4,979E-04 0,02148178 ! regulation of B cell activation GO:0050864 55 33 1,000 4,979E-04 0,02109817 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 5,604E-04 0,02333014 ! meiosis I GO:0007127 61 36 1,000 5,93E-04 0,02426197 ! keratinocyte differentiation GO:0030216 55 37 1,000 6,265E-04 0,02519845 ! establishment or maintenance of cell polarity GO:0007163 74 39 1,000 6,962E-04 0,02753563 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 6,962E-04 0,02708423 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! RNA export from nucleus GO:0006405 57 41 1,000 7,695E-04 0,02945281 ! epidermal cell differentiation GO:0009913 61 42 1,000 8,075E-04 0,03041623 ! response to calcium ion GO:0051592 65 43 1,000 8,464E-04 0,03138259 ! positive regulation of cell cycle GO:0045787 83 45 1,000 9,268E-04 0,03383603 ! response to insulin stimulus GO:0032868 71 45 1,000 9,268E-04 0,03332336 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 1,143E-03 0,04049583 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 1,284E-03 0,04480272 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! nuclear export GO:0051168 85 57 1,000 1,483E-03 0,05101541 ! positive regulation of growth GO:0045927 78 58 1,000 1,535E-03 0,0520512 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 1,535E-03 0,05131809 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 1,642E-03 0,05412197 ! negative regulation of cell growth GO:0030308 123 65 1,000 1,924E-03 0,0625411 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 1,000 1,983E-03 0,06358565 ! negative regulation of cell size GO:0045792 125 67 1,000 2,043E-03 0,06462931 ! meiosis GO:0007126 110 68 1,000 2,103E-03 0,06567207 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 1,000 2,103E-03 0,06481918 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 2,103E-03 0,06398817 ! meiotic cell cycle GO:0051321 111 69 1,000 2,165E-03 0,06502494 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 2,227E-03 0,06606094 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 1,000 2,227E-03 0,06524537 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 2,354E-03 0,06813052 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 1,000 2,419E-03 0,06916406 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 1,000 2,419E-03 0,06834068 ! regulation of actin filament-based process GO:0032970 122 74 1,000 2,485E-03 0,06937092 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 2,485E-03 0,06856428 ! regulation of peptidase activity GO:0052547 113 75 1,000 2,551E-03 0,06959117 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 2,551E-03 0,06880036 ! response to metal ion GO:0010038 114 76 1,000 2,619E-03 0,06982385 ! phosphoinositide-mediated signaling GO:0048015 122 76 1,000 2,619E-03 0,06904803 ! regulation of Ras GTPase activity GO:0032318 125 76 1,000 2,619E-03 0,06828926 ! positive regulation of ligase activity GO:0051351 114 76 1,000 2,619E-03 0,06754699 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 2,687E-03 0,06856128 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 2,756E-03 0,06957507 ! negative regulation of growth GO:0045926 140 78 1,000 2,756E-03 0,0688427 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 1,000 2,826E-03 0,06985303 ! response to unfolded protein GO:0006986 113 80 1,000 2,897E-03 0,07086287 ! response to inorganic substance GO:0010035 127 81 1,000 2,968E-03 0,07187221 ! regulation of ligase activity GO:0051340 129 82 1,000 3,041E-03 0,07288101 ! positive regulation of protein modification process GO:0031401 126 83 1,000 3,114E-03 0,07388926 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 3,114E-03 0,07315768 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 1,000 3,263E-03 0,07590402 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 127 85 1,000 3,263E-03 0,07516708 ! microtubule cytoskeleton organization GO:0000226 133 90 1,000 3,649E-03 0,08326442 ! regulation of GTPase activity GO:0043087 149 90 1,000 3,649E-03 0,08247142 ! positive regulation of cell activation GO:0050867 146 90 1,000 3,649E-03 0,08169339 GO:0002696|positive regulation of leukocyte activation, ! cell cycle arrest GO:0007050 171 93 1,000 3,891E-03 0,08629061 ! regulation of cell adhesion GO:0030155 187 94 1,000 3,973E-03 0,08729761 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,019E-03 0,10925724 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 5,019E-03 0,108264 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 5,019E-03 0,10728864 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,019E-03 0,10633071 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 5,019E-03 0,10538973 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,019E-03 0,10446526 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 5,019E-03 0,10355687 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,019E-03 0,10266413 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 5,019E-03 0,10178666 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 5,019E-03 0,10092406 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,019E-03 0,10007596 ! response to oxygen radical GO:0000305 11 5 0,000 5,019E-03 0,099242 ! negative regulation of bone resorption GO:0045779 11 5 0,000 5,019E-03 0,09842181 ! myoblast cell fate commitment GO:0048625 8 5 0,000 5,019E-03 0,09761508 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,019E-03 0,09682146 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 5,019E-03 0,09604064 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,019E-03 0,09527232 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 5,019E-03 0,09451619 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 5,019E-03 0,09377196 ! female meiosis GO:0007143 8 5 0,000 5,019E-03 0,09303937 ! nose development GO:0043584 10 5 0,000 5,019E-03 0,09231814 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 5,019E-03 0,091608 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 5,019E-03 0,0909087 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,019E-03 0,09022 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 5,019E-03 0,08954165 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 5,019E-03 0,08887343 ! cobalt ion transport GO:0006824 9 5 0,000 5,019E-03 0,08821511 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,019E-03 0,08756647 ! SMAD protein complex assembly GO:0007183 10 5 0,000 5,019E-03 0,0869273 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 5,019E-03 0,08629739 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,019E-03 0,08567654 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,019E-03 0,08506457 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,019E-03 0,08446127 ! adaptation of signaling pathway GO:0022401 9 5 0,000 5,019E-03 0,08386648 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 5,019E-03 0,08328 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,019E-03 0,08270166 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 5,019E-03 0,08213131 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,019E-03 0,08156876 ! negative regulation of histone modification GO:0031057 7 5 0,000 5,019E-03 0,08101387 ! malate metabolic process GO:0006108 8 5 0,000 5,019E-03 0,08046648 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,019E-03 0,07992644 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 5,019E-03 0,0793936 ! clathrin coat assembly GO:0048268 11 5 0,000 5,019E-03 0,07886781 ! Notch receptor processing GO:0007220 8 5 0,000 5,019E-03 0,07834894 ! phototransduction, visible light GO:0007603 7 5 0,000 5,019E-03 0,07783686 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,019E-03 0,07733143 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,019E-03 0,07683251 ! mating behavior GO:0007617 6 5 0,000 5,019E-03 0,07634 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,019E-03 0,07585376 ! copulation GO:0007620 8 5 0,000 5,019E-03 0,07537367 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,019E-03 0,07489962 ! embryonic hemopoiesis GO:0035162 13 5 0,000 5,019E-03 0,0744315 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,019E-03 0,07396919 ! apoptotic cell clearance GO:0043277 14 5 0,000 5,019E-03 0,07351259 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 5,019E-03 0,07306159 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,019E-03 0,07261609 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 5,019E-03 0,072176 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 5,019E-03 0,0717412 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,019E-03 0,07131161 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 5,019E-03 0,07088714 ! response to axon injury GO:0048678 8 5 0,000 5,019E-03 0,07046769 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,019E-03 0,07005317 ! response to protozoan GO:0001562 10 5 0,000 5,019E-03 0,06964351 ! negative regulation of heart contraction GO:0045822 12 5 0,000 5,019E-03 0,0692386 ! lymph vessel development GO:0001945 8 5 0,000 5,019E-03 0,06883838 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 5,019E-03 0,06844276 ! endochondral ossification GO:0001958 13 5 0,000 5,019E-03 0,06805165 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,019E-03 0,067665 ! single strand break repair GO:0000012 5 5 0,000 5,019E-03 0,06728271 ! parathyroid gland development GO:0060017 8 5 0,000 5,019E-03 0,06690472 ! anagen GO:0042640 7 5 0,000 5,019E-03 0,06653095 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 5,019E-03 0,06616133 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,019E-03 0,0657958 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,019E-03 0,06543428 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 5,019E-03 0,06507672 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 5,019E-03 0,06472304 ! smooth muscle tissue development GO:0048745 14 5 0,000 5,019E-03 0,06437319 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,019E-03 0,06402709 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,019E-03 0,0636847 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,019E-03 0,06334595 ! cardiac muscle fiber development GO:0048739 8 5 0,000 5,019E-03 0,06301079 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,019E-03 0,06267916 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 5,019E-03 0,06235099 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,019E-03 0,06202625 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,019E-03 0,06170487 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 5,019E-03 0,0613868 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 5,019E-03 0,061072 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,019E-03 0,06076041 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 5,019E-03 0,06045198 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 5,019E-03 0,06014666 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,019E-03 0,05984442 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 5,019E-03 0,0595452 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,019E-03 0,05924895 ! tyrosine catabolic process GO:0006572 7 5 0,000 5,019E-03 0,05895564 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,019E-03 0,05866522 ! proline biosynthetic process GO:0006561 6 5 0,000 5,019E-03 0,05837764 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,019E-03 0,05809288 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,019E-03 0,05781087 ! polyol catabolic process GO:0046174 7 5 0,000 5,019E-03 0,05753159 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 5,019E-03 0,057255 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,019E-03 0,05698105 ! sister chromatid cohesion GO:0007062 10 5 0,000 5,019E-03 0,05670971 ! response to ATP GO:0033198 6 5 0,000 5,019E-03 0,05644095 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 5,019E-03 0,05617471 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 5,019E-03 0,05591098 ! neutrophil activation GO:0042119 6 5 0,000 5,019E-03 0,05564972 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,019E-03 0,05539088 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,019E-03 0,05513444 ! response to food GO:0032094 5 5 0,000 5,019E-03 0,05488037 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,019E-03 0,05462862 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,019E-03 0,05437918 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 5,019E-03 0,054132 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,019E-03 0,05388706 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,019E-03 0,05364432 ! forebrain neuron development GO:0021884 7 5 0,000 5,019E-03 0,05340376 ! melanosome organization GO:0032438 7 5 0,000 5,019E-03 0,05316536 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,019E-03 0,05292906 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 5,019E-03 0,05269487 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,019E-03 0,05246273 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 5,019E-03 0,05223263 ! mesodermal cell fate determination GO:0007500 7 5 0,000 5,019E-03 0,05200454 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,019E-03 0,05177843 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 5,019E-03 0,05155428 ! nucleoside salvage GO:0043174 7 5 0,000 5,019E-03 0,05133207 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 5,019E-03 0,05111176 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 5,019E-03 0,05089333 ! negative regulation of platelet activation GO:0010544 8 5 0,000 5,019E-03 0,05067676 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,019E-03 0,05046203 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,019E-03 0,05024911 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,019E-03 0,05003798 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 5,019E-03 0,04982862 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,019E-03 0,049621 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 5,019E-03 0,0494151 ! depyrimidination GO:0045008 8 5 0,000 5,019E-03 0,04921091 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,019E-03 0,04900839 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,019E-03 0,04880754 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 5,019E-03 0,04860832 ! neuronal ion channel clustering GO:0045161 8 5 0,000 5,019E-03 0,04841073 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,019E-03 0,04821473 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,019E-03 0,04802032 ! monocyte differentiation GO:0030224 7 5 0,000 5,019E-03 0,04782747 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 5,019E-03 0,04763616 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 5,019E-03 0,04744637 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,019E-03 0,04725809 ! response to UV-C GO:0010225 7 5 0,000 5,019E-03 0,0470713 ! protein targeting to vacuole GO:0006623 6 5 0,000 5,019E-03 0,04688598 ! activated T cell proliferation GO:0050798 7 5 0,000 5,019E-03 0,04670212 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 5,019E-03 0,04651969 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 5,019E-03 0,04633868 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,019E-03 0,04615907 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 5,019E-03 0,04598085 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 5,019E-03 0,045804 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,019E-03 0,0456285 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 5,019E-03 0,04545435 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 5,019E-03 0,04528152 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 5,019E-03 0,04511 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 5,019E-03 0,04493977 ! response to cadmium ion GO:0046686 8 5 0,000 5,019E-03 0,04477083 ! melanosome transport GO:0032402 8 5 0,000 5,019E-03 0,04460314 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,019E-03 0,04443671 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 5,019E-03 0,04427152 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,019E-03 0,04410755 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,019E-03 0,0439448 ! positive T cell selection GO:0043368 10 5 0,000 5,019E-03 0,04378323 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 5,019E-03 0,04362286 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,019E-03 0,04346365 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 5,019E-03 0,0433056 ! ribosomal subunit assembly GO:0042257 5 5 0,000 5,019E-03 0,04314869 ! base conversion or substitution editing GO:0016553 6 5 0,000 5,019E-03 0,04299292 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 5,019E-03 0,04283827 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 5,019E-03 0,04268473 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,019E-03 0,04253228 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 5,019E-03 0,04238092 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,019E-03 0,04223064 ! histone demethylation GO:0016577 10 5 0,000 5,019E-03 0,04208141 ! mitotic recombination GO:0006312 10 5 0,000 5,019E-03 0,04193324 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 5,019E-03 0,0417861 ! regulation of sterol transport GO:0032371 7 5 0,000 5,019E-03 0,04164 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 5,019E-03 0,04149491 ! sympathetic nervous system development GO:0048485 13 5 0,000 5,019E-03 0,04135083 ! enteric nervous system development GO:0048484 9 5 0,000 5,019E-03 0,04120775 ! oxygen homeostasis GO:0032364 8 5 0,000 5,019E-03 0,04106565 ! establishment of planar polarity GO:0001736 7 5 0,000 5,019E-03 0,04092453 ! lymphocyte costimulation GO:0031294 12 5 0,000 5,019E-03 0,04078438 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 5,019E-03 0,04064519 ! transcription termination GO:0006353 8 5 0,000 5,019E-03 0,04050694 ! plasminogen activation GO:0031639 5 5 0,000 5,019E-03 0,04036963 ! B cell homeostasis GO:0001782 12 5 0,000 5,019E-03 0,04023324 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,019E-03 0,04009778 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,019E-03 0,03996322 ! regulation of hair follicle development GO:0051797 9 5 0,000 5,019E-03 0,03982956 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,019E-03 0,0396968 ! apical protein localization GO:0045176 8 5 0,000 5,019E-03 0,03956492 ! definitive hemopoiesis GO:0060216 5 5 0,000 5,019E-03 0,03943391 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,019E-03 0,03930376 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,019E-03 0,03917447 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 5,019E-03 0,03904603 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 5,019E-03 0,03891843 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,019E-03 0,03879166 ! regulation of centrosome duplication GO:0010824 6 5 0,000 5,019E-03 0,03866571 ! disaccharide metabolic process GO:0005984 9 5 0,000 5,019E-03 0,03854058 ! galactolipid metabolic process GO:0019374 8 5 0,000 5,019E-03 0,03841626 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 5,019E-03 0,03829273 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 5,019E-03 0,03817 ! determination of adult lifespan GO:0008340 8 5 0,000 5,019E-03 0,03804805 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,019E-03 0,03792688 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 5,019E-03 0,03780647 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 5,019E-03 0,03768683 ! T cell activation during immune response GO:0002286 9 5 0,000 5,019E-03 0,03756795 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 5,019E-03 0,03744981 ! negative regulation of lipase activity GO:0060192 7 5 0,000 5,019E-03 0,03733241 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 5,019E-03 0,03721575 ! neural plate development GO:0001840 7 5 0,000 5,019E-03 0,03709981 ! regulation of sensory perception GO:0051931 6 5 0,000 5,019E-03 0,03698459 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 5,019E-03 0,03687009 ! regulation of histone acetylation GO:0035065 7 5 0,000 5,019E-03 0,03675629 ! sensory cilium assembly GO:0035058 6 5 0,000 5,019E-03 0,0366432 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 5,019E-03 0,0365308 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 5,019E-03 0,03641908 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,019E-03 0,03630805 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 5,019E-03 0,03619769 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 5,019E-03 0,036088 ! receptor biosynthetic process GO:0032800 6 5 0,000 5,019E-03 0,03597897 ! penetration of zona pellucida GO:0007341 9 5 0,000 5,019E-03 0,0358706 ! drug metabolic process GO:0017144 5 5 0,000 5,019E-03 0,03576288 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,019E-03 0,03565581 ! organ regeneration GO:0031100 7 5 0,000 5,019E-03 0,03554937 ! carnitine metabolic process GO:0009437 5 5 0,000 5,019E-03 0,03544357 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 6,019E-03 0,04238583 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 6,019E-03 0,04226043 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,019E-03 0,04213576 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 6,019E-03 0,04201184 ! regulation of helicase activity GO:0051095 11 6 0,000 6,019E-03 0,04188863 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 6,019E-03 0,04176615 ! sleep GO:0030431 13 6 0,000 6,019E-03 0,04164439 ! positive regulation of axon extension GO:0045773 10 6 0,000 6,019E-03 0,04152333 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 6,019E-03 0,04140297 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 6,019E-03 0,04128331 ! forebrain regionalization GO:0021871 7 6 0,000 6,019E-03 0,04116433 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 6,019E-03 0,04104605 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 6,019E-03 0,04092844 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 6,019E-03 0,0408115 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 6,019E-03 0,04069523 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 6,019E-03 0,04057961 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 6,019E-03 0,04046466 ! neuron adhesion GO:0007158 9 6 0,000 6,019E-03 0,04035035 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 6,019E-03 0,04023669 ! signal peptide processing GO:0006465 8 6 0,000 6,019E-03 0,04012366 ! embryonic camera-type eye development GO:0031076 11 6 0,000 6,019E-03 0,04001127 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 6,019E-03 0,03989951 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 6,019E-03 0,03978837 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 6,019E-03 0,03967784 ! fibril organization GO:0043206 13 6 0,000 6,019E-03 0,03956793 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 6,019E-03 0,03945863 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 6,019E-03 0,03934993 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 6,019E-03 0,03924182 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 6,019E-03 0,03913431 ! protein refolding GO:0042026 13 6 0,000 6,019E-03 0,03902739 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 6,019E-03 0,03892105 ! rhythmic behavior GO:0007622 14 6 0,000 6,019E-03 0,03881528 ! glial cell fate commitment GO:0021781 17 6 0,000 6,019E-03 0,03871009 ! erythrocyte maturation GO:0043249 7 6 0,000 6,019E-03 0,03860547 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 6,019E-03 0,03850141 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,019E-03 0,03839791 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,019E-03 0,03829497 ! regulation of odontogenesis GO:0042481 8 6 0,000 6,019E-03 0,03819258 ! mechanosensory behavior GO:0007638 8 6 0,000 6,019E-03 0,03809073 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 6,019E-03 0,03798943 ! negative regulation of endocytosis GO:0045806 8 6 0,000 6,019E-03 0,03788866 ! response to interferon-gamma GO:0034341 12 6 0,000 6,019E-03 0,03778842 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 6,019E-03 0,03768872 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 6,019E-03 0,03758954 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 6,019E-03 0,03749088 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 6,019E-03 0,03739273 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 6,019E-03 0,0372951 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 6,019E-03 0,03719798 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 6,019E-03 0,03710136 ! cGMP-mediated signaling GO:0019934 11 6 0,000 6,019E-03 0,03700524 ! activation of MAPKKK activity GO:0000185 11 6 0,000 6,019E-03 0,03690962 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 6,019E-03 0,0368145 ! protein lipoylation GO:0009249 10 6 0,000 6,019E-03 0,03671986 ! pigment granule organization GO:0048753 11 6 0,000 6,019E-03 0,0366257 ! drug transport GO:0015893 6 6 0,000 6,019E-03 0,03653203 ! transepithelial chloride transport GO:0030321 10 6 0,000 6,019E-03 0,03643884 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 6,019E-03 0,03634612 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 6,019E-03 0,03625387 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 6,019E-03 0,03616209 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 6,019E-03 0,03607077 ! glutamate catabolic process GO:0006538 11 6 0,000 6,019E-03 0,03597991 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 6,019E-03 0,03588951 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 6,019E-03 0,03579956 ! adenohypophysis development GO:0021984 10 6 0,000 6,019E-03 0,03571006 ! response to pH GO:0009268 10 6 0,000 6,019E-03 0,03562101 ! hyperosmotic response GO:0006972 9 6 0,000 6,019E-03 0,0355324 ! microtubule nucleation GO:0007020 10 6 0,000 6,019E-03 0,03544423 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 6,019E-03 0,0353565 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 6,019E-03 0,0352692 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 6,019E-03 0,03518233 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 6,019E-03 0,03509588 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 6,019E-03 0,03500986 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 6,019E-03 0,03492426 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 6,019E-03 0,03483908 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 6,019E-03 0,03475432 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 6,019E-03 0,03466996 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 6,019E-03 0,03458601 ! purine salvage GO:0043101 9 6 0,000 6,019E-03 0,03450247 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,019E-03 0,03441934 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 6,019E-03 0,0343366 ! nucleoside transport GO:0015858 7 6 0,000 6,019E-03 0,03425425 ! organic alcohol transport GO:0015850 9 6 0,000 6,019E-03 0,03417231 ! T cell mediated immunity GO:0002456 12 6 0,000 6,019E-03 0,03409075 ! folic acid transport GO:0015884 11 6 0,000 6,019E-03 0,03400958 ! male sex determination GO:0030238 11 6 0,000 6,019E-03 0,0339288 ! carnitine transport GO:0015879 8 6 0,000 6,019E-03 0,0338484 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 6,019E-03 0,03376838 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,019E-03 0,03368874 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 6,019E-03 0,03360947 ! positive regulation of exocytosis GO:0045921 9 6 0,000 6,019E-03 0,03353057 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 6,019E-03 0,03345205 ! parturition GO:0007567 13 6 0,000 6,019E-03 0,03337389 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 6,019E-03 0,03329609 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 6,019E-03 0,03321866 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 6,019E-03 0,03314159 ! regulation of centrosome cycle GO:0046605 8 6 0,000 6,019E-03 0,03306487 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 6,019E-03 0,03298851 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 6,019E-03 0,0329125 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 6,019E-03 0,03283684 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 6,019E-03 0,03276152 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,019E-03 0,03268655 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 6,019E-03 0,03261193 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 6,019E-03 0,03253764 ! neural nucleus development GO:0048857 12 6 0,000 6,019E-03 0,03246369 ! forebrain morphogenesis GO:0048853 14 6 0,000 6,019E-03 0,03239008 ! hyaluronan metabolic process GO:0030212 7 6 0,000 6,019E-03 0,0323168 ! purine base biosynthetic process GO:0009113 14 6 0,000 6,019E-03 0,03224385 ! interaction with symbiont GO:0051702 9 6 0,000 6,019E-03 0,03217123 ! regulation of dendrite development GO:0050773 13 6 0,000 6,019E-03 0,03209893 ! anterograde axon cargo transport GO:0008089 9 6 0,000 6,019E-03 0,03202696 ! positive regulation of organ growth GO:0046622 7 6 0,000 6,019E-03 0,03195531 ! eating behavior GO:0042755 6 6 0,000 6,019E-03 0,03188398 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 6,019E-03 0,03181297 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 6,019E-03 0,03174228 ! response to copper ion GO:0046688 9 6 0,000 6,019E-03 0,03167189 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 6,019E-03 0,03160182 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 6,019E-03 0,03153206 ! establishment of melanosome localization GO:0032401 9 6 0,000 6,019E-03 0,03146261 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,019E-03 0,03139346 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 6,019E-03 0,03132461 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 6,019E-03 0,03125607 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,019E-03 0,03118783 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,019E-03 0,03111988 ! hair follicle maturation GO:0048820 8 6 0,000 6,019E-03 0,03105223 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 6,019E-03 0,03098487 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,019E-03 0,0309178 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 6,019E-03 0,03085102 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 6,019E-03 0,03078453 ! rhombomere development GO:0021546 6 6 0,000 6,019E-03 0,03071833 ! G2 phase GO:0051319 15 6 0,000 6,019E-03 0,03065241 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 6,019E-03 0,03058678 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 6,019E-03 0,03052142 ! muscle cell proliferation GO:0033002 9 6 0,000 6,019E-03 0,03045634 ! membrane to membrane docking GO:0022614 12 6 0,000 6,019E-03 0,03039154 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 6,019E-03 0,03032702 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 6,019E-03 0,03026276 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 6,019E-03 0,03019878 ! receptor internalization GO:0031623 9 6 0,000 6,019E-03 0,03013507 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,019E-03 0,03007163 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 6,019E-03 0,03000845 ! coenzyme A metabolic process GO:0015936 9 6 0,000 6,019E-03 0,02994554 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 6,019E-03 0,0298829 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 6,019E-03 0,02982051 ! peptidyl-histidine modification GO:0018202 10 6 0,000 6,019E-03 0,02975838 ! axonal fasciculation GO:0007413 10 6 0,000 6,019E-03 0,02969652 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 6,019E-03 0,0296349 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,019E-03 0,02957355 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 6,019E-03 0,02951245 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,019E-03 0,0294516 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,019E-03 0,029391 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 6,019E-03 0,02933065 ! progesterone metabolic process GO:0042448 8 6 0,000 6,019E-03 0,02927054 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,019E-03 0,02921068 ! glycolipid catabolic process GO:0019377 14 6 0,000 6,019E-03 0,02915107 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 6,019E-03 0,0290917 ! negative regulation of axon extension GO:0030517 13 6 0,000 6,019E-03 0,02903257 ! removal of superoxide radicals GO:0019430 10 6 0,000 6,019E-03 0,02897368 ! triglyceride catabolic process GO:0019433 8 6 0,000 6,019E-03 0,02891503 ! protein modification by small protein removal GO:0070646 10 6 0,000 6,019E-03 0,02885661 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 6,019E-03 0,02879844 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 6,019E-03 0,02874049 ! glial cell migration GO:0008347 11 6 0,000 6,019E-03 0,02868278 ! blastocyst growth GO:0001832 17 6 0,000 6,019E-03 0,0286253 ! pigment granule transport GO:0051904 12 6 0,000 6,019E-03 0,02856805 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 6,019E-03 0,02851103 ! cerebellar cortex formation GO:0021697 9 6 0,000 6,019E-03 0,02845423 ! catecholamine transport GO:0051937 7 6 0,000 6,019E-03 0,02839766 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 6,019E-03 0,02834132 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 6,019E-03 0,0282852 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,019E-03 0,0282293 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 6,019E-03 0,02817362 ! spindle assembly GO:0051225 6 6 0,000 6,019E-03 0,02811816 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 6,019E-03 0,02806292 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 6,019E-03 0,02800789 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 6,019E-03 0,02795308 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 6,019E-03 0,02789848 ! NAD biosynthetic process GO:0009435 9 6 0,000 6,019E-03 0,0278441 ! positive regulation of coagulation GO:0050820 11 6 0,000 6,019E-03 0,02778993 ! cellular anion homeostasis GO:0030002 9 6 0,000 6,019E-03 0,02773597 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 7,019E-03 0,0322805 ! autophagic vacuole formation GO:0000045 12 7 0,000 7,019E-03 0,03221806 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,019E-03 0,03215587 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 7,019E-03 0,03209391 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 7,019E-03 0,03203219 ! prostate gland development GO:0030850 11 7 0,000 7,019E-03 0,03197071 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 7,019E-03 0,03190946 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 7,019E-03 0,03184845 ! synaptonemal complex assembly GO:0007130 11 7 0,000 7,019E-03 0,03178767 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 7,019E-03 0,03172712 ! male meiosis GO:0007140 10 7 0,000 7,019E-03 0,0316668 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,019E-03 0,03160672 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 7,019E-03 0,03154685 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 7,019E-03 0,03148722 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 7,019E-03 0,03142781 ! oligopeptide transport GO:0006857 11 7 0,000 7,019E-03 0,03136862 ! protein amino acid sulfation GO:0006477 9 7 0,000 7,019E-03 0,03130966 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 7,019E-03 0,03125092 ! establishment of tissue polarity GO:0007164 10 7 0,000 7,019E-03 0,0311924 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 7,019E-03 0,03113409 ! RNA methylation GO:0001510 11 7 0,000 7,019E-03 0,03107601 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 7,019E-03 0,03101814 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 7,019E-03 0,03096048 ! pericardium development GO:0060039 9 7 0,000 7,019E-03 0,03090304 ! macrophage chemotaxis GO:0048246 10 7 0,000 7,019E-03 0,03084581 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 7,019E-03 0,0307888 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,019E-03 0,03073199 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,019E-03 0,03067539 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 7,019E-03 0,03061901 ! cerebral cortex cell migration GO:0021795 11 7 0,000 7,019E-03 0,03056282 ! opsonization GO:0008228 9 7 0,000 7,019E-03 0,03050685 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 7,019E-03 0,03045108 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,019E-03 0,03039551 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 7,019E-03 0,03034014 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 7,019E-03 0,03028498 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 7,019E-03 0,03023002 ! chemosensory behavior GO:0007635 9 7 0,000 7,019E-03 0,03017525 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 7,019E-03 0,03012069 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 7,019E-03 0,03006632 ! leukocyte degranulation GO:0043299 11 7 0,000 7,019E-03 0,03001214 ! positive regulation of glycolysis GO:0045821 13 7 0,000 7,019E-03 0,02995816 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 7,019E-03 0,02990438 ! positive regulation of heart rate GO:0010460 11 7 0,000 7,019E-03 0,02985079 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,019E-03 0,02979739 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 7,019E-03 0,02974418 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 7,019E-03 0,02969116 ! spinal cord patterning GO:0021511 9 7 0,000 7,019E-03 0,02963833 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 7,019E-03 0,02958568 ! thymic T cell selection GO:0045061 15 7 0,000 7,019E-03 0,02953323 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 7,019E-03 0,02948095 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 7,019E-03 0,02942887 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 7,019E-03 0,02937696 ! ovulation GO:0030728 8 7 0,000 7,019E-03 0,02932524 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 7,019E-03 0,02927371 ! histidine metabolic process GO:0006547 7 7 0,000 7,019E-03 0,02922235 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 7,019E-03 0,02917117 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 7,019E-03 0,02912017 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,019E-03 0,02906935 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 7,019E-03 0,02901871 ! thyroid hormone generation GO:0006590 11 7 0,000 7,019E-03 0,02896824 ! endosome organization GO:0007032 10 7 0,000 7,019E-03 0,02891795 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 7,019E-03 0,02886783 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 7,019E-03 0,02881789 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 7,019E-03 0,02876812 ! urea metabolic process GO:0019627 9 7 0,000 7,019E-03 0,02871852 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 7,019E-03 0,02866909 ! vesicle fusion GO:0006906 15 7 0,000 7,019E-03 0,02861983 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 7,019E-03 0,02857074 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 7,019E-03 0,02852181 ! intracellular pH reduction GO:0051452 11 7 0,000 7,019E-03 0,02847306 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 7,019E-03 0,02842447 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 7,019E-03 0,02837605 ! organ growth GO:0035265 13 7 0,000 7,019E-03 0,02832779 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 7,019E-03 0,02827969 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,019E-03 0,02823176 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 7,019E-03 0,02818399 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 7,019E-03 0,02813638 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 7,019E-03 0,02808894 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 7,019E-03 0,02804165 ! rRNA modification GO:0000154 12 7 0,000 7,019E-03 0,02799452 ! negative regulation of translational initiation GO:0045947 9 7 0,000 7,019E-03 0,02794755 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 7,019E-03 0,02790074 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 7,019E-03 0,02785408 ! protein heterooligomerization GO:0051291 10 7 0,000 7,019E-03 0,02780758 ! response to UV-B GO:0010224 11 7 0,000 7,019E-03 0,02776123 ! astrocyte development GO:0014002 15 7 0,000 7,019E-03 0,02771504 ! intermediate filament organization GO:0045109 12 7 0,000 7,019E-03 0,027669 ! cardiac muscle cell development GO:0055013 9 7 0,000 7,019E-03 0,02762312 ! fibrinolysis GO:0042730 9 7 0,000 7,019E-03 0,02757738 ! peptidyl-arginine modification GO:0018195 9 7 0,000 7,019E-03 0,0275318 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 7,019E-03 0,02748637 ! blastoderm segmentation GO:0007350 11 7 0,000 7,019E-03 0,02744109 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,019E-03 0,02739595 ! B cell lineage commitment GO:0002326 17 7 0,000 7,019E-03 0,02735097 ! DNA topological change GO:0006265 10 7 0,000 7,019E-03 0,02730613 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 7,019E-03 0,02726144 ! melanosome localization GO:0032400 10 7 0,000 7,019E-03 0,02721689 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 7,019E-03 0,02717249 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 7,019E-03 0,02712824 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 7,019E-03 0,02708413 ! mast cell activation GO:0045576 10 7 0,000 7,019E-03 0,02704016 ! multicellular organismal aging GO:0010259 11 7 0,000 7,019E-03 0,02699634 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 7,019E-03 0,02695265 ! gas homeostasis GO:0033483 12 7 0,000 7,019E-03 0,02690911 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 7,019E-03 0,02686571 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 7,019E-03 0,02682245 ! Schwann cell development GO:0014044 16 7 0,000 7,019E-03 0,02677932 ! dendrite morphogenesis GO:0048813 12 7 0,000 7,019E-03 0,02673634 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 7,019E-03 0,02669349 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 7,019E-03 0,02665078 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 7,019E-03 0,02660821 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 7,019E-03 0,02656577 ! neural tube patterning GO:0021532 8 7 0,000 7,019E-03 0,02652347 ! histone ubiquitination GO:0016574 10 7 0,000 7,019E-03 0,0264813 ! regulation of meiosis GO:0040020 12 7 0,000 7,019E-03 0,02643927 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 7,019E-03 0,02639737 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 7,019E-03 0,0263556 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 7,019E-03 0,02631396 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 7,019E-03 0,02627246 ! regulation of lipid transport GO:0032368 13 7 0,000 7,019E-03 0,02623109 ! regulation of cell division GO:0051302 9 7 0,000 7,019E-03 0,02618984 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 7,019E-03 0,02614873 ! neutrophil homeostasis GO:0001780 8 7 0,000 7,019E-03 0,02610774 ! regulation of macrophage activation GO:0043030 12 7 0,000 7,019E-03 0,02606688 ! negative regulation of nuclear division GO:0051784 18 7 0,000 7,019E-03 0,02602615 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 7,019E-03 0,02598555 ! diuresis GO:0030146 11 7 0,000 7,019E-03 0,02594508 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 7,019E-03 0,02590473 ! positive regulation of epidermis development GO:0045684 11 7 0,000 7,019E-03 0,0258645 ! thiamin metabolic process GO:0006772 8 7 0,000 7,019E-03 0,0258244 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 7,019E-03 0,02578443 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 7,019E-03 0,02574457 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 7,019E-03 0,02570484 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 7,019E-03 0,02566524 ! dopamine biosynthetic process GO:0042416 15 7 0,000 7,019E-03 0,02562575 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 7,019E-03 0,02558639 ! lymph node development GO:0048535 9 7 0,000 7,019E-03 0,02554715 ! anterior/posterior axis specification GO:0009948 11 7 0,000 7,019E-03 0,02550802 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 7,019E-03 0,02546902 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 7,019E-03 0,02543014 ! positive regulation of glucose import GO:0046326 7 7 0,000 7,019E-03 0,02539137 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 7,019E-03 0,02535272 ! ATP catabolic process GO:0006200 10 7 0,000 7,019E-03 0,02531419 ! establishment of pigment granule localization GO:0051905 13 7 0,000 7,019E-03 0,02527578 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 7,019E-03 0,02523748 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 7,019E-03 0,0251993 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 7,019E-03 0,02516124 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 7,019E-03 0,02512329 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 7,019E-03 0,02508545 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,019E-03 0,02504773 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 7,019E-03 0,02501012 ! muscle adaptation GO:0043500 12 7 0,000 7,019E-03 0,02497262 ! amino sugar catabolic process GO:0046348 9 7 0,000 7,019E-03 0,02493524 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 7,019E-03 0,02489797 ! retina homeostasis GO:0001895 9 7 0,000 7,019E-03 0,0248608 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,019E-03 0,02482375 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 7,019E-03 0,02478681 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 7,019E-03 0,02474998 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 7,019E-03 0,02471326 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,019E-03 0,02467665 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 8,018E-03 0,02814673 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 8,018E-03 0,02810515 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 8,018E-03 0,0280637 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 8,018E-03 0,02802237 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 8,018E-03 0,02798116 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 8,018E-03 0,02794007 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 8,018E-03 0,0278991 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 8,018E-03 0,02785825 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 8,018E-03 0,02781752 ! cell proliferation in forebrain GO:0021846 10 8 0,000 8,018E-03 0,02777691 ! neutral lipid catabolic process GO:0046461 11 8 0,000 8,018E-03 0,02773642 ! N-glycan processing GO:0006491 12 8 0,000 8,018E-03 0,02769605 ! Golgi to endosome transport GO:0006895 16 8 0,000 8,018E-03 0,02765579 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 8,018E-03 0,02761566 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 8,018E-03 0,02757563 ! mRNA stabilization GO:0048255 16 8 0,000 8,018E-03 0,02753573 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 8,018E-03 0,02749593 ! neurotransmitter uptake GO:0001504 10 8 0,000 8,018E-03 0,02745626 ! lipoprotein transport GO:0042953 14 8 0,000 8,018E-03 0,0274167 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,018E-03 0,02737725 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 8,018E-03 0,02733791 ! middle ear morphogenesis GO:0042474 9 8 0,000 8,018E-03 0,02729869 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 8,018E-03 0,02725958 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 8,018E-03 0,02722058 ! bile acid and bile salt transport GO:0015721 12 8 0,000 8,018E-03 0,0271817 ! ganglioside metabolic process GO:0001573 16 8 0,000 8,018E-03 0,02714292 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 8,018E-03 0,02710425 ! reflex GO:0060004 16 8 0,000 8,018E-03 0,0270657 ! positive regulation of isotype switching GO:0045830 16 8 0,000 8,018E-03 0,02702725 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 8,018E-03 0,02698892 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 8,018E-03 0,02695069 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 8,018E-03 0,02691257 ! glycerolipid catabolic process GO:0046503 11 8 0,000 8,018E-03 0,02687456 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 8,018E-03 0,02683665 ! hemoglobin metabolic process GO:0020027 12 8 0,000 8,018E-03 0,02679885 ! ceramide biosynthetic process GO:0046513 9 8 0,000 8,018E-03 0,02676116 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 8,018E-03 0,02672358 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 8,018E-03 0,0266861 ! adrenal gland development GO:0030325 18 8 0,000 8,018E-03 0,02664872 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 8,018E-03 0,02661145 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 8,018E-03 0,02657428 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 8,018E-03 0,02653722 ! proline metabolic process GO:0006560 9 8 0,000 8,018E-03 0,02650026 ! polyamine biosynthetic process GO:0006596 9 8 0,000 8,018E-03 0,0264634 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 8,018E-03 0,02642665 ! regulation of pigmentation during development GO:0048070 18 8 0,000 8,018E-03 0,02639 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 8,018E-03 0,02635344 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 8,018E-03 0,02631699 ! regulation of type I interferon production GO:0032479 8 8 0,000 8,018E-03 0,02628064 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 8,018E-03 0,0262444 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 8,018E-03 0,02620825 ! galactose metabolic process GO:0006012 14 8 0,000 8,018E-03 0,0261722 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,018E-03 0,02613625 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,018E-03 0,02610039 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 8,018E-03 0,02606464 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 8,018E-03 0,02602898 ! ruffle organization GO:0031529 12 8 0,000 8,018E-03 0,02599342 ! osteoblast development GO:0002076 14 8 0,000 8,018E-03 0,02595796 ! macroautophagy GO:0016236 14 8 0,000 8,018E-03 0,0259226 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 8,018E-03 0,02588733 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,018E-03 0,02585216 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 8,018E-03 0,02581708 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 8,018E-03 0,0257821 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 8,018E-03 0,02574721 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 8,018E-03 0,02571241 ! protein retention in ER lumen GO:0006621 16 8 0,000 8,018E-03 0,02567771 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 8,018E-03 0,02564311 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 8,018E-03 0,0256086 ! regulation of circadian rhythm GO:0042752 13 8 0,000 8,018E-03 0,02557418 ! pigment granule localization GO:0051875 14 8 0,000 8,018E-03 0,02553985 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 8,018E-03 0,02550561 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 8,018E-03 0,02547147 ! response to tropane GO:0014073 14 8 0,000 8,018E-03 0,02543742 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 8,018E-03 0,02540345 ! embryonic axis specification GO:0000578 12 8 0,000 8,018E-03 0,02536958 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 8,018E-03 0,0253358 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 8,018E-03 0,02530211 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 8,018E-03 0,02526851 ! snRNA metabolic process GO:0016073 10 8 0,000 8,018E-03 0,025235 GO:0016180|snRNA processing, ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 8,018E-03 0,02520157 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 8,018E-03 0,02516824 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 8,018E-03 0,02513499 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 8,018E-03 0,02510183 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 8,018E-03 0,02506876 ! establishment of nucleus localization GO:0040023 14 8 0,000 8,018E-03 0,02503577 ! icosanoid secretion GO:0032309 12 8 0,000 8,018E-03 0,02500287 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 8,018E-03 0,02497006 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 8,018E-03 0,02493733 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 8,018E-03 0,02490469 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 8,018E-03 0,02487214 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 8,018E-03 0,02483967 ! S phase GO:0051320 8 8 0,000 8,018E-03 0,02480728 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 8,018E-03 0,02477498 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 8,018E-03 0,02474277 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 8,018E-03 0,02471063 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 8,018E-03 0,02467858 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 8,018E-03 0,02464661 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 8,018E-03 0,02461473 ! melanin biosynthetic process GO:0042438 11 8 0,000 8,018E-03 0,02458293 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 8,018E-03 0,02455121 ! regulation of synaptogenesis GO:0051963 12 8 0,000 8,018E-03 0,02451957 ! hormone catabolic process GO:0042447 13 8 0,000 8,018E-03 0,02448801 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 8,018E-03 0,02445654 ! quaternary ammonium group transport GO:0015697 10 8 0,000 8,018E-03 0,02442514 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 8,018E-03 0,02439383 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 8,018E-03 0,02436259 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 8,018E-03 0,02433144 ! regulation of telomere maintenance GO:0032204 10 8 0,000 8,018E-03 0,02430037 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 8,018E-03 0,02426937 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 8,018E-03 0,02423845 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 8,018E-03 0,02420762 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 8,018E-03 0,02417686 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 8,018E-03 0,02414618 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 8,018E-03 0,02411557 ! negative regulation of B cell activation GO:0050869 17 8 0,000 8,018E-03 0,02408505 ! behavioral response to nicotine GO:0035095 13 8 0,000 8,018E-03 0,0240546 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,018E-03 0,02402423 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 8,018E-03 0,02399393 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 8,018E-03 0,02396371 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 8,018E-03 0,02393357 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 8,018E-03 0,0239035 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 9,016E-03 0,02684488 ! regulation of developmental growth GO:0048638 14 9 0,000 9,016E-03 0,02681124 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 9,016E-03 0,02677768 ! telencephalon cell migration GO:0022029 16 9 0,000 9,016E-03 0,02674421 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 9,016E-03 0,02671082 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 9,016E-03 0,02667752 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 9,016E-03 0,02664429 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 9,016E-03 0,02661115 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 9,016E-03 0,0265781 ! cell volume homeostasis GO:0006884 14 9 0,000 9,016E-03 0,02654512 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 9,016E-03 0,02651223 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 9,016E-03 0,02647942 ! UTP metabolic process GO:0046051 10 9 0,000 9,016E-03 0,02644669 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 9,016E-03 0,02641404 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 9,016E-03 0,02638147 ! smoothened signaling pathway GO:0007224 10 9 0,000 9,016E-03 0,02634898 ! protein complex disassembly GO:0043241 17 9 0,000 9,016E-03 0,02631657 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 9,016E-03 0,02628424 ! estrogen metabolic process GO:0008210 16 9 0,000 9,016E-03 0,02625199 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 9,016E-03 0,02621981 ! photoreceptor cell development GO:0042461 17 9 0,000 9,016E-03 0,02618772 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 9,016E-03 0,02615571 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 9,016E-03 0,02612377 ! microtubule bundle formation GO:0001578 14 9 0,000 9,016E-03 0,02609191 ! T-helper 1 type immune response GO:0042088 13 9 0,000 9,016E-03 0,02606013 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 9,016E-03 0,02602843 ! lung alveolus development GO:0048286 18 9 0,000 9,016E-03 0,0259968 ! ciliary or flagellar motility GO:0001539 10 9 0,000 9,016E-03 0,02596525 ! pseudouridine synthesis GO:0001522 10 9 0,000 9,016E-03 0,02593378 ! endothelial cell differentiation GO:0045446 17 9 0,000 9,016E-03 0,02590238 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 9,016E-03 0,02587106 ! regulation of exit from mitosis GO:0007096 12 9 0,000 9,016E-03 0,02583982 ! endoderm development GO:0007492 12 9 0,000 9,016E-03 0,02580865 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 9,016E-03 0,02577755 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 9,016E-03 0,02574653 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 9,016E-03 0,02571559 ! astrocyte differentiation GO:0048708 17 9 0,000 9,016E-03 0,02568472 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 9,016E-03 0,02565392 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 9,016E-03 0,0256232 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,016E-03 0,02559255 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 9,016E-03 0,02556197 ! reverse cholesterol transport GO:0043691 17 9 0,000 9,016E-03 0,02553147 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 9,016E-03 0,02550104 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 9,016E-03 0,02547068 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 9,016E-03 0,02544039 ! macrophage activation GO:0042116 14 9 0,000 9,016E-03 0,02541018 ! multicellular organism growth GO:0035264 16 9 0,000 9,016E-03 0,02538003 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 9,016E-03 0,02534996 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 9,016E-03 0,02531996 ! neuron apoptosis GO:0051402 12 9 0,000 9,016E-03 0,02529003 ! lens development in camera-type eye GO:0002088 11 9 0,000 9,016E-03 0,02526018 ! positive regulation of vasodilation GO:0045909 14 9 0,000 9,016E-03 0,02523039 ! retinoic acid metabolic process GO:0042573 11 9 0,000 9,016E-03 0,02520067 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 9,016E-03 0,02517102 ! positive regulation of translational initiation GO:0045948 10 9 0,000 9,016E-03 0,02514144 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 9,016E-03 0,02511193 ! Schwann cell differentiation GO:0014037 20 9 0,000 9,016E-03 0,0250825 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 9,016E-03 0,02505312 ! regulation of gliogenesis GO:0014013 21 9 0,000 9,016E-03 0,02502382 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 9,016E-03 0,02499459 ! oligodendrocyte development GO:0014003 13 9 0,000 9,016E-03 0,02496542 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 9,016E-03 0,02493633 ! segment specification GO:0007379 11 9 0,000 9,016E-03 0,0249073 ! cellular extravasation GO:0045123 12 9 0,000 9,016E-03 0,02487834 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,016E-03 0,02484944 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 9,016E-03 0,02482061 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 9,016E-03 0,02479185 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,016E-03 0,02476316 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 9,016E-03 0,02473453 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 9,016E-03 0,02470597 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 9,016E-03 0,02467747 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 9,016E-03 0,02464904 ! response to amine stimulus GO:0014075 13 9 0,000 9,016E-03 0,02462068 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 9,016E-03 0,02459238 ! erythrocyte development GO:0048821 13 9 0,000 9,016E-03 0,02456414 ! renal water homeostasis GO:0003091 13 9 0,000 9,016E-03 0,02453597 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 9,016E-03 0,02450787 ! nucleosome disassembly GO:0006337 13 9 0,000 9,016E-03 0,02447983 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 9,016E-03 0,02445185 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 9,016E-03 0,02442394 ! induction of an organ GO:0001759 13 9 0,000 9,016E-03 0,02439609 ! leukocyte activation during immune response GO:0002366 15 9 0,000 9,016E-03 0,0243683 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 9,016E-03 0,02434058 ! cerebellum morphogenesis GO:0021587 13 9 0,000 9,016E-03 0,02431292 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 9,016E-03 0,02428532 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 9,016E-03 0,02425779 ! sterol catabolic process GO:0016127 11 9 0,000 9,016E-03 0,02423032 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 9,016E-03 0,02420291 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 9,016E-03 0,02417556 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 9,016E-03 0,02414827 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 9,016E-03 0,02412105 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 9,016E-03 0,02409388 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 9,016E-03 0,02406678 ! prophase GO:0051324 12 9 0,000 9,016E-03 0,02403974 ! neuroblast proliferation GO:0007405 19 9 0,000 9,016E-03 0,02401276 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 9,016E-03 0,02398584 ! peptidyl-threonine modification GO:0018210 22 9 0,000 9,016E-03 0,02395898 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 9,016E-03 0,02393218 ! ubiquinone metabolic process GO:0006743 11 9 0,000 9,016E-03 0,02390544 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 9,016E-03 0,02387876 ! acid secretion GO:0046717 14 9 0,000 9,016E-03 0,02385214 ! purine base metabolic process GO:0006144 18 9 0,000 9,016E-03 0,02382558 ! detection of calcium ion GO:0005513 13 9 0,000 9,016E-03 0,02379908 ! myeloid cell homeostasis GO:0002262 10 9 0,000 9,016E-03 0,02377263 ! regulation of fibrinolysis GO:0051917 14 9 0,000 9,016E-03 0,02374625 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 9,016E-03 0,02371992 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 9,016E-03 0,02369365 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 9,016E-03 0,02366744 ! regulation of muscle adaptation GO:0043502 12 9 0,000 9,016E-03 0,02364129 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,016E-03 0,0236152 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 9,016E-03 0,02358916 ! prepulse inhibition GO:0060134 14 9 0,000 9,016E-03 0,02356318 ! sequestering of metal ion GO:0051238 12 9 0,000 9,016E-03 0,02353726 ! lamellipodium assembly GO:0030032 12 9 0,000 9,016E-03 0,02351139 ! regulation of embryonic development GO:0045995 17 9 0,000 9,016E-03 0,02348559 ! mitochondrion localization GO:0051646 15 9 0,000 9,016E-03 0,02345983 ! localization within membrane GO:0051668 15 9 0,000 9,016E-03 0,02343414 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01001318 0,02599703 ! axon extension GO:0048675 13 10 0,000 0,01001318 0,02596862 ! neuron fate specification GO:0048665 12 10 0,000 0,01001318 0,02594027 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01001318 0,02591198 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01001318 0,02588375 ! associative learning GO:0008306 19 10 0,000 0,01001318 0,02585559 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01001318 0,02582749 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01001318 0,02579944 ! CTP metabolic process GO:0046036 11 10 0,000 0,01001318 0,02577146 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01001318 0,02574354 ! GTP metabolic process GO:0046039 11 10 0,000 0,01001318 0,02571568 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01001318 0,02568788 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01001318 0,02566014 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01001318 0,02563246 ! social behavior GO:0035176 15 10 0,000 0,01001318 0,02560484 ! sulfate transport GO:0008272 12 10 0,000 0,01001318 0,02557727 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01001318 0,02554977 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01001318 0,02552233 ! artery development GO:0060840 20 10 0,000 0,01001318 0,02549494 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01001318 0,02546762 ! response to pain GO:0048265 20 10 0,000 0,01001318 0,02544035 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01001318 0,02541314 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01001318 0,02538599 ! phospholipid efflux GO:0033700 17 10 0,000 0,01001318 0,0253589 ! hippocampus development GO:0021766 19 10 0,000 0,01001318 0,02533186 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01001318 0,02530488 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01001318 0,02527796 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01001318 0,0252511 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01001318 0,0252243 ! pathogenesis GO:0009405 13 10 0,000 0,01001318 0,02519755 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01001318 0,02517085 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01001318 0,02514422 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01001318 0,02511764 ! protein targeting to ER GO:0045047 21 10 0,000 0,01001318 0,02509112 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01001318 0,02506465 ! arginine catabolic process GO:0006527 12 10 0,000 0,01001318 0,02503824 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01001318 0,02501188 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01001318 0,02498558 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01001318 0,02495934 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01001318 0,02493314 ! B cell proliferation GO:0042100 16 10 0,000 0,01001318 0,02490701 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01001318 0,02488093 ! mannose metabolic process GO:0006013 11 10 0,000 0,01001318 0,0248549 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01001318 0,02482893 ! forebrain cell migration GO:0021885 17 10 0,000 0,01001318 0,02480301 ! lipid digestion GO:0044241 15 10 0,000 0,01001318 0,02477715 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01001318 0,02475134 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01001318 0,02472558 ! receptor clustering GO:0043113 18 10 0,000 0,01001318 0,02469988 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01001318 0,02467423 ! UV protection GO:0009650 14 10 0,000 0,01001318 0,02464864 ! entry into host cell GO:0030260 21 10 0,000 0,01001318 0,0246231 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01001318 0,02459761 ! behavioral fear response GO:0001662 19 10 0,000 0,01001318 0,02457217 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01001318 0,02454678 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01001318 0,02452145 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01001318 0,02449617 ! protein homotetramerization GO:0051289 20 10 0,000 0,01001318 0,02447094 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01001318 0,02444577 ! response to dsRNA GO:0043331 19 10 0,000 0,01001318 0,02442064 ! DNA ligation GO:0006266 16 10 0,000 0,01001318 0,02439557 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01001318 0,02437055 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01001318 0,02434558 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01001318 0,02432066 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01001318 0,02429579 ! postreplication repair GO:0006301 16 10 0,000 0,01001318 0,02427098 ! fucose catabolic process GO:0019317 17 10 0,000 0,01001318 0,02424621 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01001318 0,0242215 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01001318 0,02419683 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01001318 0,02417221 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01001318 0,02414765 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01001318 0,02412313 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01001318 0,02409867 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01001318 0,02407425 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01001318 0,02404989 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01001318 0,02402557 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01001318 0,0240013 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01001318 0,02397708 ! oocyte differentiation GO:0009994 14 10 0,000 0,01001318 0,02395291 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01001318 0,02392879 ! spleen development GO:0048536 17 10 0,000 0,01001318 0,02390472 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01001318 0,02388069 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01001318 0,02385671 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01001318 0,02383279 ! blastocyst formation GO:0001825 14 10 0,000 0,01001318 0,0238089 ! embryonic gut development GO:0048566 13 10 0,000 0,01001318 0,02378507 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01001318 0,02376129 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01001318 0,02373755 ! activation of innate immune response GO:0002218 10 10 0,000 0,01001318 0,02371386 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01001318 0,02369022 ! insulin secretion GO:0030073 18 10 0,000 0,01001318 0,02366662 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01001318 0,02364307 ! response to nicotine GO:0035094 18 10 0,000 0,01001318 0,02361957 ! nucleus localization GO:0051647 16 10 0,000 0,01001318 0,02359611 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01001318 0,02357271 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01100925 0,02589192 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01100925 0,02586628 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01100925 0,0258407 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01100925 0,02581516 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01100925 0,02578968 ! virus-host interaction GO:0019048 20 11 0,000 0,01100925 0,02576424 ! thyroid gland development GO:0030878 20 11 0,000 0,01100925 0,02573886 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01100925 0,02571353 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 0,01100925 0,02568824 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01100925 0,02566301 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01100925 0,02563783 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01100925 0,02561269 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01100925 0,0255876 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01100925 0,02556257 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01100925 0,02553758 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01100925 0,02551264 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01100925 0,02548775 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01100925 0,02546291 ! bone resorption GO:0045453 16 11 0,000 0,01100925 0,02543811 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01100925 0,02541337 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01100925 0,02538867 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01100925 0,02536402 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01100925 0,02533942 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01100925 0,02531487 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01100925 0,02529036 ! syncytium formation GO:0006949 15 11 0,000 0,01100925 0,0252659 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01100925 0,02524149 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01100925 0,02521713 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01100925 0,02519281 ! Golgi organization GO:0007030 19 11 0,000 0,01100925 0,02516854 ! response to X-ray GO:0010165 19 11 0,000 0,01100925 0,02514432 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01100925 0,02512014 ! adult heart development GO:0007512 12 11 0,000 0,01100925 0,02509601 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01100925 0,02507192 ! epithelial cell development GO:0002064 16 11 0,000 0,01100925 0,02504788 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01100925 0,02502389 ! temperature homeostasis GO:0001659 16 11 0,000 0,01100925 0,02499995 ! L-glutamate transport GO:0015813 15 11 0,000 0,01100925 0,02497605 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01100925 0,02495219 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01100925 0,02492838 ! motor axon guidance GO:0008045 17 11 0,000 0,01100925 0,02490462 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01100925 0,0248809 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01100925 0,02485723 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01100925 0,0248336 ! stem cell development GO:0048864 30 11 0,000 0,01100925 0,02481001 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01100925 0,02478647 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01100925 0,02476298 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01100925 0,02473953 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01100925 0,02471612 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01100925 0,02469276 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01100925 0,02466945 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01100925 0,02464617 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01100925 0,02462294 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01100925 0,02459976 ! cranial nerve development GO:0021545 14 11 0,000 0,01100925 0,02457662 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01100925 0,02455352 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01100925 0,02453046 ! salivary gland development GO:0007431 24 11 0,000 0,01100925 0,02450745 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01100925 0,02448448 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01100925 0,02446156 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01100925 0,02443868 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01100925 0,02441584 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01100925 0,02439304 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01100925 0,02437028 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01100925 0,02434757 ! cholesterol efflux GO:0033344 20 11 0,000 0,01100925 0,0243249 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01100925 0,02430227 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01100925 0,02427969 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01100925 0,02425714 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01100925 0,02423464 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01100925 0,02421218 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01100925 0,02418976 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01100925 0,02416739 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01100925 0,02414505 ! defense response to fungus GO:0050832 13 11 0,000 0,01100925 0,02412276 ! lysogeny GO:0030069 20 11 0,000 0,01100925 0,0241005 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01100925 0,02407829 ! acrosome reaction GO:0007340 14 11 0,000 0,01100925 0,02405612 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01100925 0,02403399 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01100925 0,0240119 ! rRNA transcription GO:0009303 19 12 0,000 0,01200436 0,02615826 ! reproductive cellular process GO:0048610 15 12 0,000 0,01200436 0,02613426 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01200436 0,0261103 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01200436 0,02608639 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01200436 0,02606253 ! phosphate transport GO:0006817 15 12 0,000 0,01200436 0,0260387 ! peroxisomal transport GO:0043574 22 12 0,000 0,01200436 0,02601492 ! mating GO:0007618 16 12 0,000 0,01200436 0,02599119 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01200436 0,02596749 ! heart looping GO:0001947 15 12 0,000 0,01200436 0,02594384 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01200436 0,02592024 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01200436 0,02589667 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01200436 0,02587315 ! T cell selection GO:0045058 25 12 0,000 0,01200436 0,02584967 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01200436 0,02582624 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01200436 0,02580285 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01200436 0,02577949 ! plasma membrane organization GO:0007009 19 12 0,000 0,01200436 0,02575619 ! focal adhesion formation GO:0048041 28 12 0,000 0,01200436 0,02573292 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01200436 0,02570969 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01200436 0,02568651 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01200436 0,02566337 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01200436 0,02564027 ! monoamine transport GO:0015844 14 12 0,000 0,01200436 0,02561721 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01200436 0,0255942 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01200436 0,02557122 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01200436 0,02554829 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01200436 0,0255254 ! regulation of organ growth GO:0046620 14 12 0,000 0,01200436 0,02550254 ! vasoconstriction GO:0042310 18 12 0,000 0,01200436 0,02547973 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01200436 0,02545696 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01200436 0,02543423 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01200436 0,02541154 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01200436 0,0253889 ! histone deacetylation GO:0016575 14 12 0,000 0,01200436 0,02536629 ! histone acetylation GO:0016573 27 12 0,000 0,01200436 0,02534372 ! DNA methylation GO:0006306 19 12 0,000 0,01200436 0,02532119 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01200436 0,0252987 ! protein sumoylation GO:0016925 14 12 0,000 0,01200436 0,02527626 ! chromatin silencing GO:0006342 23 12 0,000 0,01200436 0,02525385 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01200436 0,02523148 ! gland morphogenesis GO:0022612 24 12 0,000 0,01200436 0,02520915 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01200436 0,02518686 ! zymogen activation GO:0031638 16 12 0,000 0,01200436 0,02516461 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01200436 0,0251424 ! nucleosome positioning GO:0016584 13 12 0,000 0,01200436 0,02512023 ! T cell homeostasis GO:0043029 22 12 0,000 0,01200436 0,0250981 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01200436 0,025076 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01200436 0,02505395 ! response to gamma radiation GO:0010332 21 12 0,000 0,01200436 0,02503193 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01200436 0,02500996 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01200436 0,02498802 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01200436 0,02496612 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01200436 0,02494426 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01200436 0,02492243 ! male genitalia development GO:0030539 15 12 0,000 0,01200436 0,02490065 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01200436 0,0248789 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01200436 0,02485719 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01200436 0,02483552 ! developmental induction GO:0031128 16 12 0,000 0,01200436 0,02481389 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01200436 0,02479229 ! response to cold GO:0009409 15 12 0,000 0,01200436 0,02477073 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01200436 0,02474921 ! respiratory burst GO:0045730 22 13 0,000 0,01299852 0,02677559 ! lactation GO:0007595 22 13 0,000 0,01299852 0,02675237 ! tRNA modification GO:0006400 15 13 0,000 0,01299852 0,02672919 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01299852 0,02670604 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01299852 0,02668294 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01299852 0,02665988 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01299852 0,02663686 ! water transport GO:0006833 21 13 0,000 0,01299852 0,02661388 GO:0042044|fluid transport, ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01299852 0,02659093 ! copper ion transport GO:0006825 15 13 0,000 0,01299852 0,02656803 ! filopodium assembly GO:0046847 21 13 0,000 0,01299852 0,02654517 ! lipid localization GO:0010876 25 13 0,000 0,01299852 0,02652234 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,01299852 0,02649955 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01299852 0,02647681 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01299852 0,0264541 ! T cell proliferation GO:0042098 24 13 0,000 0,01299852 0,02643143 ! organelle fusion GO:0048284 29 13 0,000 0,01299852 0,0264088 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01299852 0,02638621 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01299852 0,02636366 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01299852 0,02634115 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01299852 0,02631867 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01299852 0,02629623 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01299852 0,02627383 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01299852 0,02625147 ! methionine metabolic process GO:0006555 16 13 0,000 0,01299852 0,02622915 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01299852 0,02620687 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01299852 0,02618462 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01299852 0,02616241 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01299852 0,02614024 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01299852 0,0261181 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01299852 0,02609601 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01299852 0,02607395 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01299852 0,02605193 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01299852 0,02602994 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01299852 0,02600799 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01299852 0,02598608 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01299852 0,02596421 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01299852 0,02594237 ! cellular pigmentation GO:0033059 24 13 0,000 0,01299852 0,02592057 ! histone methylation GO:0016571 16 13 0,000 0,01299852 0,02589881 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01299852 0,02587708 ! oxygen transport GO:0015671 20 13 0,000 0,01299852 0,02585539 ! regulation of axon extension GO:0030516 26 13 0,000 0,01299852 0,02583374 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01299852 0,02581212 ! detection of bacterium GO:0016045 13 13 0,000 0,01299852 0,02579054 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01299852 0,02576899 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01299852 0,02574748 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01299852 0,02572601 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01299852 0,02570457 ! actin filament polymerization GO:0030041 18 13 0,000 0,01299852 0,02568317 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01399173 0,0276226 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01399173 0,02759964 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01399173 0,02757672 ! neuron maturation GO:0042551 24 14 0,000 0,01399173 0,02755383 ! regulation of S phase GO:0033261 25 14 0,000 0,01399173 0,02753098 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01399173 0,02750817 ! myotube differentiation GO:0014902 21 14 0,000 0,01399173 0,0274854 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01399173 0,02746267 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01399173 0,02743997 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01399173 0,02741731 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01399173 0,02739469 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01399173 0,02737211 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01399173 0,02734956 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01399173 0,02732705 ! cartilage condensation GO:0001502 22 14 0,000 0,01399173 0,02730458 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01399173 0,02728214 ! response to cAMP GO:0051591 20 14 0,000 0,01399173 0,02725974 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01399173 0,02723738 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01399173 0,02721505 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01399173 0,02719277 ! limbic system development GO:0021761 25 14 0,000 0,01399173 0,02717051 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01399173 0,0271483 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01399173 0,02712612 ! palate development GO:0060021 19 14 0,000 0,01399173 0,02710397 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01399173 0,02708187 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01399173 0,02705979 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01399173 0,02703776 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01399173 0,02701576 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01399173 0,02699379 ! arginine metabolic process GO:0006525 17 14 0,000 0,01399173 0,02697187 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01399173 0,02694997 ! glycine metabolic process GO:0006544 22 14 0,000 0,01399173 0,02692812 ! pituitary gland development GO:0021983 24 14 0,000 0,01399173 0,02690629 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01399173 0,02688451 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01399173 0,02686276 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01399173 0,02684104 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01399173 0,02681936 ! NAD metabolic process GO:0019674 25 14 0,000 0,01399173 0,02679771 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01399173 0,0267761 ! regulation of heart rate GO:0002027 26 14 0,000 0,01399173 0,02675453 ! exocrine system development GO:0035272 29 14 0,000 0,01399173 0,02673298 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01399173 0,02671148 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01399173 0,02669001 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01399173 0,02666857 ! axon cargo transport GO:0008088 29 14 0,000 0,01399173 0,02664716 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01399173 0,0266258 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01399173 0,02660446 ! genitalia development GO:0048806 18 14 0,000 0,01399173 0,02658316 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01399173 0,02656189 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01399173 0,02654066 ! tissue regeneration GO:0042246 24 14 0,000 0,01399173 0,02651946 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01399173 0,0264983 ! water homeostasis GO:0030104 23 14 0,000 0,01399173 0,02647717 ! cofactor transport GO:0051181 22 14 0,000 0,01399173 0,02645607 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01399173 0,02643501 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01399173 0,02641398 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01399173 0,02639298 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01399173 0,02637202 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01399173 0,02635108 ! cell killing GO:0001906 22 14 0,000 0,01399173 0,02633019 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01399173 0,02630932 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01399173 0,02628849 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01399173 0,0262677 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01399173 0,02624693 ! microspike assembly GO:0030035 25 14 0,000 0,01399173 0,0262262 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01399173 0,0262055 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01498399 0,0280418 ! superoxide anion generation GO:0042554 19 15 0,000 0,01498399 0,0280197 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01498399 0,02799764 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01498399 0,02797561 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01498399 0,02795362 ! inositol metabolic process GO:0006020 21 15 0,000 0,01498399 0,02793166 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01498399 0,02790973 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01498399 0,02788784 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01498399 0,02786599 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01498399 0,02784417 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01498399 0,02782238 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01498399 0,02780062 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01498399 0,02777891 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01498399 0,02775722 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01498399 0,02773557 ! response to osmotic stress GO:0006970 23 15 0,000 0,01498399 0,02771395 ! vesicle coating GO:0006901 26 15 0,000 0,01498399 0,02769237 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01498399 0,02767082 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01498399 0,0276493 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01498399 0,02762782 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01498399 0,02760637 ! bone mineralization GO:0030282 17 15 0,000 0,01498399 0,02758495 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01498399 0,02756356 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01498399 0,02754221 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01498399 0,0275209 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01498399 0,02749961 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01498399 0,02747836 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01498399 0,02745714 ! ribosome assembly GO:0042255 17 15 0,000 0,01498399 0,02743596 ! cerebellum development GO:0021549 19 15 0,000 0,01498399 0,0274148 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01498399 0,02739368 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01498399 0,02737259 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01498399 0,02735154 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01498399 0,02733051 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01498399 0,02730952 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01498399 0,02728856 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01498399 0,02726764 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01498399 0,02724674 ! muscle maintenance GO:0046716 21 15 0,000 0,01498399 0,02722588 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01498399 0,02720505 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01498399 0,02718425 ! intestinal absorption GO:0050892 22 15 0,000 0,01498399 0,02716348 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01498399 0,02714275 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01498399 0,02712204 ! gas transport GO:0015669 23 15 0,000 0,01498399 0,02710137 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01498399 0,02708073 ! organic cation transport GO:0015695 19 15 0,000 0,01498399 0,02706012 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01498399 0,02703954 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01498399 0,027019 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,01498399 0,02699848 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01498399 0,026978 ! cilium assembly GO:0042384 22 15 0,000 0,01498399 0,02695754 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01498399 0,02693712 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01498399 0,02691673 ! peptide hormone processing GO:0016486 23 15 0,000 0,01498399 0,02689637 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01498399 0,02687604 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,0159753 0,02863246 ! bone remodeling GO:0046849 24 16 0,000 0,0159753 0,02861085 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,0159753 0,02858928 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,0159753 0,02856773 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,0159753 0,02854622 ! bile acid metabolic process GO:0008206 23 16 0,000 0,0159753 0,02852474 ! axis specification GO:0009798 26 16 0,000 0,0159753 0,02850329 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,0159753 0,02848188 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,0159753 0,0284605 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0159753 0,02843914 ! centrosome cycle GO:0007098 18 16 0,000 0,0159753 0,02841783 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,0159753 0,02839654 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,0159753 0,02837528 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,0159753 0,02835406 ! cellular response to starvation GO:0009267 26 16 0,000 0,0159753 0,02833287 ! DNA integration GO:0015074 25 16 0,000 0,0159753 0,02831171 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,0159753 0,02829058 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,0159753 0,02826949 ! regulation of exocytosis GO:0017157 28 16 0,000 0,0159753 0,02824842 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,0159753 0,02822739 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,0159753 0,02820638 ! regulation of vasodilation GO:0042312 26 16 0,000 0,0159753 0,02818541 ! DNA replication initiation GO:0006270 26 16 0,000 0,0159753 0,02816447 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,0159753 0,02814356 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,0159753 0,02812269 ! neuron recognition GO:0008038 27 16 0,000 0,0159753 0,02810184 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,0159753 0,02808102 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,0159753 0,02806024 ! G1 phase GO:0051318 28 16 0,000 0,0159753 0,02803948 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,0159753 0,02801876 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0159753 0,02799806 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,0159753 0,0279774 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,0159753 0,02795677 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,0159753 0,02793617 ! NADP metabolic process GO:0006739 22 16 0,000 0,0159753 0,0279156 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,0159753 0,02789505 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,0159753 0,02787454 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,0159753 0,02785406 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,0159753 0,02783361 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0159753 0,02781319 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,0159753 0,0277928 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,0159753 0,02777244 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,0159753 0,02775211 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,0159753 0,02773181 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,0159753 0,02771153 ! defense response to virus GO:0051607 28 16 0,000 0,0159753 0,02769129 ! peptide hormone secretion GO:0030072 26 16 0,000 0,0159753 0,02767108 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,01696566 0,02936507 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,01696566 0,02934367 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,01696566 0,02932229 ! zinc ion transport GO:0006829 22 17 0,000 0,01696566 0,02930095 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01696566 0,02927964 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,01696566 0,02925837 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,01696566 0,02923712 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,01696566 0,0292159 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,01696566 0,02919471 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,01696566 0,02917356 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,01696566 0,02915243 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,01696566 0,02913134 ! adult walking behavior GO:0007628 30 17 0,000 0,01696566 0,02911028 ! patterning of blood vessels GO:0001569 27 17 0,000 0,01696566 0,02908924 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,01696566 0,02906824 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,01696566 0,02904727 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,01696566 0,02902632 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,01696566 0,02900541 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,01696566 0,02898453 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,01696566 0,02896368 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01696566 0,02894285 ! protein polyubiquitination GO:0000209 31 17 0,000 0,01696566 0,02892206 ! cerebral cortex development GO:0021987 34 17 0,000 0,01696566 0,0289013 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,01696566 0,02888057 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01696566 0,02885986 ! fructose metabolic process GO:0006000 24 17 0,000 0,01696566 0,02883919 ! membrane budding GO:0006900 30 17 0,000 0,01696566 0,02881855 ! neuromuscular junction development GO:0007528 25 17 0,000 0,01696566 0,02879793 ! L-amino acid transport GO:0015807 27 17 0,000 0,01696566 0,02877735 ! regulation of protein binding GO:0043393 29 17 0,000 0,01696566 0,02875679 ! peptide secretion GO:0002790 30 17 0,000 0,01696566 0,02873627 ! stem cell differentiation GO:0048863 40 17 0,000 0,01696566 0,02871577 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01696566 0,0286953 ! intermediate filament-based process GO:0045103 29 17 0,000 0,01696566 0,02867487 ! protein export from nucleus GO:0006611 26 17 0,000 0,01696566 0,02865446 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,01696566 0,02863408 ! diencephalon development GO:0021536 27 17 0,000 0,01696566 0,02861372 ! oogenesis GO:0048477 25 17 0,000 0,01696566 0,0285934 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,01696566 0,02857311 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,01696566 0,02855284 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01696566 0,02853261 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,01696566 0,0285124 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,01696566 0,02849222 ! steroid catabolic process GO:0006706 24 17 0,000 0,01696566 0,02847207 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,01696566 0,02845195 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,01696566 0,02843186 ! nerve development GO:0021675 20 17 0,000 0,01696566 0,02841179 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,01696566 0,02839176 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,01696566 0,02837175 ! protein secretion GO:0009306 32 18 0,000 0,01795508 0,03000521 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,01795508 0,02998409 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,01795508 0,02996301 ! negative regulation of defense response GO:0031348 21 18 0,000 0,01795508 0,02994195 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,01795508 0,02992092 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,01795508 0,02989993 ! metencephalon development GO:0022037 25 18 0,000 0,01795508 0,02987896 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,01795508 0,02985802 ! hormone secretion GO:0046879 28 18 0,000 0,01795508 0,02983711 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,01795508 0,02981623 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,01795508 0,02979538 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,01795508 0,02977456 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01795508 0,02975377 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,01795508 0,029733 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,01795508 0,02971227 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01795508 0,02969156 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,01795508 0,02967089 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,01795508 0,02965024 ! glial cell development GO:0021782 31 18 0,000 0,01795508 0,02962962 ! keratinization GO:0031424 19 18 0,000 0,01795508 0,02960903 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,01795508 0,02958847 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,01795508 0,02956794 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,01795508 0,02954743 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,01795508 0,02952695 ! vacuolar transport GO:0007034 26 18 0,000 0,01795508 0,02950651 ! pigmentation during development GO:0048066 35 18 0,000 0,01795508 0,02948609 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,01795508 0,0294657 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,01795508 0,02944533 ! fucose metabolic process GO:0006004 27 18 0,000 0,01795508 0,029425 ! actin filament bundle formation GO:0051017 30 18 0,000 0,01795508 0,02940469 ! body fluid secretion GO:0007589 27 18 0,000 0,01795508 0,02938441 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,01795508 0,02936416 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,01795508 0,02934394 ! negative regulation of immune response GO:0050777 33 18 0,000 0,01795508 0,02932374 ! heart process GO:0003015 32 18 0,000 0,01795508 0,02930357 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,01795508 0,02928343 ! sensory perception of pain GO:0019233 26 18 0,000 0,01795508 0,02926332 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,01795508 0,02924324 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,01795508 0,02922318 ! somitogenesis GO:0001756 25 18 0,000 0,01795508 0,02920315 ! neural crest cell migration GO:0001755 28 18 0,000 0,01795508 0,02918315 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,01795508 0,02916317 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,01795508 0,02914323 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,01795508 0,0291233 ! synaptogenesis GO:0007416 28 18 0,000 0,01795508 0,02910341 ! cell-cell junction organization GO:0045216 28 18 0,000 0,01795508 0,02908355 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01795508 0,02906371 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,01795508 0,0290439 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,01795508 0,02902411 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,01795508 0,02900435 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,01795508 0,02898462 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,01795508 0,02896492 ! gut development GO:0048565 29 18 0,000 0,01795508 0,02894524 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,01795508 0,02892559 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,01795508 0,02890597 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,01795508 0,02888637 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,01894355 0,03045599 ! positive regulation of translation GO:0045727 29 19 0,000 0,01894355 0,03043537 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,01894355 0,03041477 ! glycerol metabolic process GO:0006071 22 19 0,000 0,01894355 0,03039421 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,01894355 0,03037367 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,01894355 0,03035316 ! endothelial cell migration GO:0043542 24 19 0,000 0,01894355 0,03033268 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,01894355 0,03031223 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,01894355 0,0302918 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,01894355 0,0302714 ! memory GO:0007613 28 19 0,000 0,01894355 0,03025103 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,01894355 0,03023069 ! pancreas development GO:0031016 27 19 0,000 0,01894355 0,03021037 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,01894355 0,03019008 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,01894355 0,03016982 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,01894355 0,03014959 ! central nervous system neuron development GO:0021954 33 19 0,000 0,01894355 0,03012938 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,01894355 0,0301092 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,01894355 0,03008905 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,01894355 0,03006892 ! heme metabolic process GO:0042168 29 19 0,000 0,01894355 0,03004882 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,01894355 0,03002875 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,01894355 0,0300087 ! response to fungus GO:0009620 21 19 0,000 0,01894355 0,02998868 ! peptide cross-linking GO:0018149 35 19 0,000 0,01894355 0,02996869 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,01894355 0,02994872 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,01894355 0,02992878 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,01894355 0,02990887 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,01894355 0,02988899 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,01894355 0,02986913 ! vitamin transport GO:0051180 26 19 0,000 0,01894355 0,02984929 ! sarcomere organization GO:0045214 26 19 0,000 0,01894355 0,02982949 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,01894355 0,0298097 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,01894355 0,02978995 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,01894355 0,02977022 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,01894355 0,02975052 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,01894355 0,02973084 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,01894355 0,02971119 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,01993107 0,03123939 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,01993107 0,03121877 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,01993107 0,03119817 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,01993107 0,03117761 ! lipid phosphorylation GO:0046834 28 20 0,000 0,01993107 0,03115707 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,01993107 0,03113656 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,01993107 0,03111607 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,01993107 0,03109562 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,01993107 0,03107518 ! response to alkaloid GO:0043279 34 20 0,000 0,01993107 0,03105478 ! sensory perception of taste GO:0050909 26 20 0,000 0,01993107 0,0310344 ! response to retinoic acid GO:0032526 27 20 0,000 0,01993107 0,03101405 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,01993107 0,03099373 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,01993107 0,03097343 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,01993107 0,03095316 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,01993107 0,03093292 ! chromosome condensation GO:0030261 32 20 0,000 0,01993107 0,0309127 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,01993107 0,03089251 ! sex determination GO:0007530 32 20 0,000 0,01993107 0,03087234 ! plasma membrane fusion GO:0045026 24 20 0,000 0,01993107 0,03085221 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,01993107 0,03083209 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,01993107 0,03081201 ! cytolysis GO:0019835 21 20 0,000 0,01993107 0,03079195 ! renal system process GO:0003014 35 20 0,000 0,01993107 0,03077191 ! vasodilation GO:0042311 36 20 0,000 0,01993107 0,03075191 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,01993107 0,03073192 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,01993107 0,03071197 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,01993107 0,03069204 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,01993107 0,03067213 ! hormone transport GO:0009914 30 20 0,000 0,01993107 0,03065226 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,01993107 0,0306324 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,01993107 0,03061258 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,01993107 0,03059278 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,01993107 0,030573 ! sperm-egg recognition GO:0035036 24 20 0,000 0,01993107 0,03055325 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,01993107 0,03053353 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,01993107 0,03051383 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02091765 0,0320036 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02091765 0,03198298 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02091765 0,03196239 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02091765 0,03194182 ! iron ion transport GO:0006826 49 21 0,000 0,02091765 0,03192128 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02091765 0,03190076 ! microtubule-based transport GO:0010970 41 21 0,000 0,02091765 0,03188027 ! vesicle docking GO:0048278 28 21 0,000 0,02091765 0,03185981 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02091765 0,03183938 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02091765 0,03181897 ! response to ethanol GO:0045471 38 21 0,000 0,02091765 0,03179858 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02091765 0,03177822 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02091765 0,03175789 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02091765 0,03173759 ! response to vitamin A GO:0033189 28 21 0,000 0,02091765 0,03171731 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02091765 0,03169705 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02091765 0,03167683 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,02091765 0,03165662 ! response to starvation GO:0042594 35 21 0,000 0,02091765 0,03163645 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02091765 0,0316163 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02091765 0,03159617 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02091765 0,03157607 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02091765 0,031556 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02091765 0,03153595 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02091765 0,03151593 ! visual learning GO:0008542 38 21 0,000 0,02091765 0,03149593 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,02091765 0,03147596 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02091765 0,03145601 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02091765 0,03143609 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02091765 0,03141619 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02091765 0,03139632 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02091765 0,03137648 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02091765 0,03135666 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02091765 0,03133686 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02091765 0,03131709 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02091765 0,03129734 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02091765 0,03127762 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02091765 0,03125793 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02190329 0,0327102 ! regulation of cell killing GO:0031341 37 22 0,000 0,02190329 0,03268962 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02190329 0,03266908 ! gluconeogenesis GO:0006094 26 22 0,000 0,02190329 0,03264856 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02190329 0,03262806 ! viral genome replication GO:0019079 31 22 0,000 0,02190329 0,03260759 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02190329 0,03258715 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02190329 0,03256673 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02190329 0,03254634 ! response to vitamin GO:0033273 31 22 0,000 0,02190329 0,03252597 ! molting cycle process GO:0022404 43 22 0,000 0,02190329 0,03250563 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02190329 0,03248531 ! regeneration GO:0031099 37 22 0,000 0,02190329 0,03246502 ! phototransduction GO:0007602 29 22 0,000 0,02190329 0,03244476 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02190329 0,03242452 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02190329 0,0324043 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02190329 0,03238411 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02190329 0,03236395 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02190329 0,03234381 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02190329 0,0323237 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02190329 0,03230361 ! pallium development GO:0021543 43 22 0,000 0,02190329 0,03228354 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02190329 0,0322635 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02190329 0,03224349 ! platelet activation GO:0030168 33 22 0,000 0,02190329 0,0322235 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02190329 0,03220353 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02190329 0,03218359 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02190329 0,03216368 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02190329 0,03214379 ! cell-cell recognition GO:0009988 28 22 0,000 0,02190329 0,03212392 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02190329 0,03210408 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02190329 0,03208426 ! neural tube closure GO:0001843 35 22 0,000 0,02190329 0,03206447 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02190329 0,0320447 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02190329 0,03202496 ! protein tetramerization GO:0051262 43 22 0,000 0,02190329 0,03200524 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02288798 0,0334235 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02288798 0,03340294 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02288798 0,03338241 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02288798 0,0333619 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02288798 0,03334143 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02288798 0,03332097 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02288798 0,03330054 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02288798 0,03328014 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02288798 0,03325976 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02288798 0,0332394 ! tube lumen formation GO:0035148 37 23 0,000 0,02288798 0,03321907 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02288798 0,03319877 ! dendrite development GO:0016358 41 23 0,000 0,02288798 0,03317849 ! vasculogenesis GO:0001570 38 23 0,000 0,02288798 0,03315823 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02288798 0,033138 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02288798 0,03311779 ! lysosome organization GO:0007040 41 23 0,000 0,02288798 0,03309761 ! digestive system process GO:0022600 35 23 0,000 0,02288798 0,03307746 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02288798 0,03305732 ! vesicle targeting GO:0006903 35 23 0,000 0,02288798 0,03303721 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02288798 0,03301713 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02288798 0,03299707 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02288798 0,03297704 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02288798 0,03295703 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02288798 0,03293704 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02288798 0,03291708 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02288798 0,03289714 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02288798 0,03287723 ! membrane depolarization GO:0051899 40 23 0,000 0,02288798 0,03285734 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02288798 0,03283747 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02288798 0,03281763 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02288798 0,03279781 ! DNA modification GO:0006304 33 23 0,000 0,02288798 0,03277802 ! collagen fibril organization GO:0030199 50 23 0,000 0,02288798 0,03275825 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02288798 0,03273851 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02288798 0,03271878 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02288798 0,03269909 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02288798 0,03267941 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02288798 0,03265976 ! collagen catabolic process GO:0030574 29 23 0,000 0,02288798 0,03264013 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02288798 0,03262053 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02288798 0,03260095 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02288798 0,03258139 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02288798 0,03256186 ! blastocyst development GO:0001824 41 23 0,000 0,02288798 0,03254235 ! actin filament-based movement GO:0030048 37 23 0,000 0,02288798 0,03252286 ! protein stabilization GO:0050821 34 23 0,000 0,02288798 0,0325034 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,02387173 0,03388016 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,02387173 0,03385991 ! myelination GO:0042552 39 24 0,000 0,02387173 0,03383968 ! initiation of viral infection GO:0019059 47 24 0,000 0,02387173 0,03381948 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,02387173 0,0337993 ! leukocyte adhesion GO:0007159 49 24 0,000 0,02387173 0,03377914 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,02387173 0,03375901 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,02387173 0,03373891 ! visual behavior GO:0007632 42 24 0,000 0,02387173 0,03371882 ! spinal cord development GO:0021510 41 24 0,000 0,02387173 0,03369877 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,02387173 0,03367873 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,02387173 0,03365872 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,02387173 0,03363873 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,02387173 0,03361877 ! cell aging GO:0007569 38 24 0,000 0,02387173 0,03359883 ! osteoblast differentiation GO:0001649 43 24 0,000 0,02387173 0,03357891 ! response to toxin GO:0009636 38 24 0,000 0,02387173 0,03355902 ! primary neural tube formation GO:0014020 37 24 0,000 0,02387173 0,03353915 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,02387173 0,03351931 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,02387173 0,03349948 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,02387173 0,03347968 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,02387173 0,03345991 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,02387173 0,03344016 ! pentose metabolic process GO:0019321 33 24 0,000 0,02387173 0,03342043 ! immunoglobulin production GO:0002377 37 24 0,000 0,02387173 0,03340072 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,02387173 0,03338104 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,02387173 0,03336138 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,02387173 0,03334175 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,02387173 0,03332213 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,02387173 0,03330254 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,02387173 0,03328298 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,02387173 0,03326343 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,02387173 0,03324391 ! neuron fate commitment GO:0048663 38 25 0,000 0,02485455 0,03459228 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,02485455 0,034572 ! superoxide metabolic process GO:0006801 33 25 0,000 0,02485455 0,03455175 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,02485455 0,03453152 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,02485455 0,03451131 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,02485455 0,03449113 ! vacuole organization GO:0007033 43 25 0,000 0,02485455 0,03447097 ! receptor metabolic process GO:0043112 40 25 0,000 0,02485455 0,03445084 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,02485455 0,03443073 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,02485455 0,03441064 ! regulation of behavior GO:0050795 45 25 0,000 0,02485455 0,03439058 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,02485455 0,03437053 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,02485455 0,03435052 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,02485455 0,03433052 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02485455 0,03431055 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,02485455 0,0342906 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,02485455 0,03427068 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,02485455 0,03425078 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,02485455 0,0342309 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,02485455 0,03421104 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,02485455 0,03419121 ! regulation of amine transport GO:0051952 44 25 0,000 0,02485455 0,0341714 ! liver development GO:0001889 44 25 0,000 0,02485455 0,03415161 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,02583642 0,03548022 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,02583642 0,0354597 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,02583642 0,0354392 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,02583642 0,03541873 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,02583642 0,03539828 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,02583642 0,03537785 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,02583642 0,03535745 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,02583642 0,03533707 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,02583642 0,03531672 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,02583642 0,03529638 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,02583642 0,03527607 ! sperm motility GO:0030317 31 26 0,000 0,02583642 0,03525579 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,02583642 0,03523553 ! male gonad development GO:0008584 39 26 0,000 0,02583642 0,03521529 ! neural crest cell development GO:0014032 44 26 0,000 0,02583642 0,03519507 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,02583642 0,03517488 ! cell fate determination GO:0001709 54 26 0,000 0,02583642 0,03515471 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,02583642 0,03513457 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,02583642 0,03511444 ! detection of visible light GO:0009584 33 26 0,000 0,02583642 0,03509434 ! spermatid development GO:0007286 40 26 0,000 0,02583642 0,03507427 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,02583642 0,03505421 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,02583642 0,03503418 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,02583642 0,03501417 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,02583642 0,03499419 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02681735 0,03630209 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,02681735 0,0362814 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,02681735 0,03626072 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,02681735 0,03624007 ! membrane docking GO:0022406 40 27 0,000 0,02681735 0,03621945 ! circadian rhythm GO:0007623 44 27 0,000 0,02681735 0,03619884 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,02681735 0,03617827 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,02681735 0,03615771 ! autophagy GO:0006914 36 27 0,000 0,02681735 0,03613718 ! myofibril assembly GO:0030239 40 27 0,000 0,02681735 0,03611667 GO:0055002|striated muscle cell development, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,02681735 0,03609618 ! peptide transport GO:0015833 46 27 0,000 0,02681735 0,03607572 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,02681735 0,03605528 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,02681735 0,03603486 ! negative regulation of cell development GO:0010721 67 27 0,000 0,02681735 0,03601447 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,02681735 0,0359941 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,02681735 0,03597375 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,02681735 0,03595343 ! detection of light stimulus GO:0009583 35 27 0,000 0,02681735 0,03593313 ! glutathione metabolic process GO:0006749 35 27 0,000 0,02681735 0,03591285 ! lipid oxidation GO:0034440 39 27 0,000 0,02681735 0,03589259 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,02681735 0,03587236 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,02681735 0,03585215 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,02681735 0,03583196 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,02779734 0,03712048 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,02779734 0,0370996 ! translational initiation GO:0006413 48 28 0,000 0,02779734 0,03707875 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,02779734 0,03705792 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,02779734 0,03703711 ! regulation of pH GO:0006885 40 28 0,000 0,02779734 0,03701633 ! catechol metabolic process GO:0009712 46 28 0,000 0,02779734 0,03699557 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,02779734 0,03697483 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,02779734 0,03695411 ! iron ion homeostasis GO:0055072 49 28 0,000 0,02779734 0,03693342 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,02779734 0,03691276 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,02779734 0,03689211 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,02779734 0,03687149 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,02779734 0,03685089 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,02779734 0,03683031 ! gene silencing GO:0016458 47 28 0,000 0,02779734 0,03680976 ! regulation of coagulation GO:0050818 42 28 0,000 0,02779734 0,03678923 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0287764 0,03806376 ! phenol metabolic process GO:0018958 47 29 0,000 0,0287764 0,03804256 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0287764 0,03802138 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0287764 0,03800022 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0287764 0,03797908 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0287764 0,03795797 ! cholesterol transport GO:0030301 48 29 0,000 0,0287764 0,03793689 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0287764 0,03791582 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0287764 0,03789478 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0287764 0,03787376 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0287764 0,03785277 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0287764 0,0378318 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0287764 0,03781085 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0287764 0,03778992 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0287764 0,03776902 ! muscle cell development GO:0055001 42 29 0,000 0,0287764 0,03774814 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0287764 0,03772729 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0287764 0,03770646 ! mesoderm formation GO:0001707 52 29 0,000 0,0287764 0,03768565 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0287764 0,03766486 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0287764 0,0376441 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,0287764 0,03762336 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0287764 0,03760264 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,0287764 0,03758195 ! spermatid differentiation GO:0048515 45 29 0,000 0,0287764 0,03756127 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0287764 0,03754062 ! neural tube formation GO:0001841 46 29 0,000 0,0287764 0,03752 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,02975452 0,03877401 ! organic anion transport GO:0015711 50 30 0,000 0,02975452 0,03875273 ! cell junction assembly GO:0034329 65 30 0,000 0,02975452 0,03873147 ! acute-phase response GO:0006953 49 30 0,000 0,02975452 0,03871024 ! segmentation GO:0035282 43 30 0,000 0,02975452 0,03868903 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,02975452 0,03866784 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,02975452 0,03864667 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,02975452 0,03862553 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,02975452 0,03860441 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,02975452 0,03858332 ! ceramide metabolic process GO:0006672 47 30 0,000 0,02975452 0,03856225 ! formation of primary germ layer GO:0001704 54 30 0,000 0,02975452 0,0385412 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,02975452 0,03852017 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,02975452 0,03849917 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,02975452 0,03847819 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,02975452 0,03845723 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,02975452 0,03843629 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,02975452 0,03841538 ! response to heat GO:0009408 43 30 0,000 0,02975452 0,03839449 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,02975452 0,03837363 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,0307317 0,03961235 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,0307317 0,03959084 ! post-embryonic development GO:0009791 50 31 0,000 0,0307317 0,03956936 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,0307317 0,0395479 ! regulation of innate immune response GO:0045088 42 31 0,000 0,0307317 0,03952646 ! ovulation cycle process GO:0022602 46 31 0,000 0,0307317 0,03950505 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,0307317 0,03948366 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,0307317 0,0394623 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,0307317 0,03944096 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,0307317 0,03941964 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,0307317 0,03939834 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,0307317 0,03937707 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,0307317 0,03935582 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,0307317 0,03933459 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,0307317 0,03931338 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,0307317 0,0392922 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,0307317 0,03927104 ! tissue homeostasis GO:0001894 45 31 0,000 0,0307317 0,03924991 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,03170795 0,04047497 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,03170795 0,04045321 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,03170795 0,04043147 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,03170795 0,04040976 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,03170795 0,04038807 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,03170795 0,0403664 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,03170795 0,04034475 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,03170795 0,04032313 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,03170795 0,04030153 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,03170795 0,04027996 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,03170795 0,04025841 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,03170795 0,04023688 ! telencephalon development GO:0021537 59 32 0,000 0,03170795 0,04021537 ! ovulation cycle GO:0042698 48 32 0,000 0,03170795 0,04019389 ! cofactor catabolic process GO:0051187 52 32 0,000 0,03170795 0,04017243 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,03170795 0,040151 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,03170795 0,04012958 ! placenta development GO:0001890 45 32 0,000 0,03170795 0,04010819 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,03170795 0,04008682 ! vesicle localization GO:0051648 50 32 0,000 0,03170795 0,04006548 ! regulation of muscle development GO:0048634 52 33 0,000 0,03268326 0,04127588 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,03268326 0,04125393 ! negative regulation of secretion GO:0051048 53 33 0,000 0,03268326 0,041232 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,03268326 0,04121009 ! glial cell differentiation GO:0010001 65 33 0,000 0,03268326 0,0411882 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,03268326 0,04116634 ! sister chromatid segregation GO:0000819 48 33 0,000 0,03268326 0,0411445 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,03268326 0,04112269 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,03268326 0,04110089 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,03268326 0,04107912 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,03268326 0,04105738 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,03268326 0,04103565 ! protein targeting to membrane GO:0006612 63 33 0,000 0,03268326 0,04101395 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,03268326 0,04099228 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,03268326 0,04097062 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,03268326 0,04094899 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,03268326 0,04092738 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,03268326 0,04090579 ! cytokine production GO:0001816 49 33 0,000 0,03268326 0,04088423 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,03268326 0,04086269 ! RNA modification GO:0009451 43 33 0,000 0,03268326 0,04084117 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,03268326 0,04081968 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,03365765 0,04201451 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,03365765 0,04199242 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,03365765 0,04197036 ! actomyosin structure organization GO:0031032 48 34 0,000 0,03365765 0,04194832 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,03365765 0,0419263 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,03365765 0,0419043 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,03365765 0,04188232 ! positive regulation of cell development GO:0010720 58 34 0,000 0,03365765 0,04186037 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,03365765 0,04183845 ! cell fate specification GO:0001708 49 34 0,000 0,03365765 0,04181654 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,03365765 0,04179466 ! peripheral nervous system development GO:0007422 58 34 0,000 0,03365765 0,0417728 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,03365765 0,04175096 ! adult locomotory behavior GO:0008344 54 34 0,000 0,03365765 0,04172915 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,03365765 0,04170736 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,03463109 0,04289122 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,03463109 0,04286885 ! collagen metabolic process GO:0032963 47 35 0,000 0,03463109 0,0428465 ! cell junction organization GO:0034330 72 35 0,000 0,03463109 0,04282417 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,03463109 0,04280187 ! metanephros development GO:0001656 61 35 0,000 0,03463109 0,04277959 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,03463109 0,04275733 ! female gonad development GO:0008585 55 35 0,000 0,03463109 0,04273509 ! lipid homeostasis GO:0055088 63 35 0,000 0,03463109 0,04271288 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,03463109 0,04269069 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03463109 0,04266853 ! hindbrain development GO:0030902 56 35 0,000 0,03463109 0,04264639 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,03463109 0,04262427 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,03463109 0,04260217 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,03463109 0,0425801 ! cytokinesis GO:0000910 57 35 0,000 0,03463109 0,04255805 ! embryonic organ development GO:0048568 53 35 0,000 0,03463109 0,04253602 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,03463109 0,04251401 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,03463109 0,04249203 ! protein homooligomerization GO:0051260 59 35 0,000 0,03463109 0,04247007 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,03560361 0,04364017 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,03560361 0,04361764 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,03560361 0,04359513 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,03560361 0,04357265 ! spliceosome assembly GO:0000245 65 36 0,000 0,03560361 0,04355019 ! mismatch repair GO:0006298 42 36 0,000 0,03560361 0,04352775 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,03560361 0,04350534 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,03560361 0,04348295 ! regulation of proteolysis GO:0030162 53 36 0,000 0,03560361 0,04346058 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,03560361 0,04343824 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,03560361 0,04341591 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,03560361 0,04339361 ! eye morphogenesis GO:0048592 64 36 0,000 0,03560361 0,04337134 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,03560361 0,04334909 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,0365752 0,0445092 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,0365752 0,04448639 ! mammary gland development GO:0030879 73 37 0,000 0,0365752 0,0444636 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,0365752 0,04444083 ! ear morphogenesis GO:0042471 50 37 0,000 0,0365752 0,04441809 ! odontogenesis GO:0042476 60 37 0,000 0,0365752 0,04439537 ! negative regulation of binding GO:0051100 59 37 0,000 0,0365752 0,04437267 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,0365752 0,04435 ! tissue remodeling GO:0048771 65 37 0,000 0,0365752 0,04432735 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,0365752 0,04430472 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,0365752 0,04428211 ! natural killer cell activation GO:0030101 45 37 0,000 0,0365752 0,04425953 ! polyol metabolic process GO:0019751 47 37 0,000 0,0365752 0,04423697 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,0365752 0,04421444 ! glucan metabolic process GO:0044042 54 37 0,000 0,0365752 0,04419193 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,03754585 0,04534163 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,03754585 0,04531857 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,03754585 0,04529553 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,03754585 0,04527251 ! feeding behavior GO:0007631 50 38 0,000 0,03754585 0,04524952 ! organic ether metabolic process GO:0018904 51 38 0,000 0,03754585 0,04522655 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,03754585 0,04520361 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,03754585 0,04518068 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,03754585 0,04515778 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,03754585 0,04513491 ! ion transmembrane transport GO:0034220 58 38 0,000 0,03754585 0,04511206 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,03754585 0,04508923 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,03754585 0,04506642 ! neuron migration GO:0001764 59 38 0,000 0,03754585 0,04504363 ! maintenance of protein location GO:0045185 72 38 0,000 0,03754585 0,04502087 ! pigment metabolic process GO:0042440 66 38 0,000 0,03754585 0,04499814 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,03754585 0,04497542 ! mRNA catabolic process GO:0006402 58 39 0,000 0,03851558 0,04611376 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,03851558 0,04609051 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,03851558 0,04606727 ! neural tube development GO:0021915 58 39 0,000 0,03851558 0,04604407 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,03851558 0,04602088 ! regulation of protein stability GO:0031647 58 39 0,000 0,03851558 0,04599772 ! female gamete generation GO:0007292 50 39 0,000 0,03851558 0,04597458 ! aerobic respiration GO:0009060 56 39 0,000 0,03851558 0,04595147 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,03851558 0,04592838 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,03948438 0,04705999 ! Notch signaling pathway GO:0007219 64 40 0,000 0,03948438 0,04703636 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,03948438 0,04701276 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,03948438 0,04698918 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,03948438 0,04696563 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,03948438 0,0469421 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,03948438 0,04691859 ! phagocytosis GO:0006909 65 40 0,000 0,03948438 0,04689511 ! mesenchymal cell development GO:0014031 70 40 0,000 0,03948438 0,04687165 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,03948438 0,04684822 ! B cell differentiation GO:0030183 70 40 0,000 0,03948438 0,0468248 ! pigmentation GO:0043473 81 40 0,000 0,03948438 0,04680141 ! developmental growth GO:0048589 70 40 0,000 0,03948438 0,04677805 ! synapse organization GO:0050808 61 40 0,000 0,03948438 0,04675471 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,04045225 0,0478769 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,04045225 0,04785304 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,04045225 0,04782919 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,04045225 0,04780537 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,04045225 0,04778158 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,04045225 0,04775781 ! cell growth GO:0016049 71 41 0,000 0,04045225 0,04773406 ! maintenance of location in cell GO:0051651 77 41 0,000 0,04045225 0,04771033 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,0414192 0,0488265 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,0414192 0,04880226 ! learning GO:0007612 75 42 0,000 0,0414192 0,04877804 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,0414192 0,04875384 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,0414192 0,04872967 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,0414192 0,04870553 ! gliogenesis GO:0042063 85 42 0,000 0,0414192 0,0486814 ! endosome transport GO:0016197 74 42 0,000 0,0414192 0,0486573 ! male sex differentiation GO:0046661 62 42 0,000 0,0414192 0,04863323 ! double-strand break repair GO:0006302 75 42 0,000 0,0414192 0,04860917 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,0414192 0,04858515 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,0414192 0,04856114 ! mitochondrial transport GO:0006839 66 43 0,000 0,04238521 0,04966919 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,04238521 0,04964468 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,04238521 0,04962018 ! regulation of tube size GO:0035150 69 43 0,000 0,04238521 0,04959572 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,04238521 0,04957127 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,04238521 0,04954685 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,04238521 0,04952246 ! T cell differentiation GO:0030217 78 43 0,000 0,04238521 0,04949809 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,04238521 0,04947374 ! amino acid activation GO:0043038 61 43 0,000 0,04238521 0,04944942 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,04238521 0,04942512 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,04335031 0,05052568 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,04335031 0,05050088 ! cellular component disassembly GO:0022411 66 44 0,000 0,04335031 0,0504761 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,04335031 0,05045134 ! peptide metabolic process GO:0006518 64 44 0,000 0,04335031 0,05042661 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,04335031 0,0504019 ! inner ear development GO:0048839 66 44 0,000 0,04335031 0,05037722 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,04335031 0,05035256 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,04335031 0,05032793 ! chromatin remodeling GO:0006338 73 44 0,000 0,04335031 0,05030332 ! biopolymer methylation GO:0043414 67 44 0,000 0,04335031 0,05027873 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,04335031 0,05025417 ! JNK cascade GO:0007254 66 44 0,000 0,04335031 0,05022963 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,04335031 0,05020512 ! regulation of cell shape GO:0008360 83 44 0,000 0,04335031 0,05018063 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,04431448 0,0512717 ! positive regulation of binding GO:0051099 67 45 0,000 0,04431448 0,05124671 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,04431448 0,05122175 ! regulation of ion transport GO:0043269 60 45 0,000 0,04431448 0,05119682 ! glucose transport GO:0015758 60 45 0,000 0,04431448 0,0511719 ! neuromuscular process GO:0050905 89 45 0,000 0,04431448 0,05114701 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,04431448 0,05112215 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,04431448 0,05109731 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,04431448 0,05107249 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,04527773 0,0521573 ! regulation of translational initiation GO:0006446 70 46 0,000 0,04527773 0,052132 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,04527773 0,05210671 ! regulation of action potential GO:0001508 80 46 0,000 0,04527773 0,05208146 ! hexose transport GO:0008645 62 46 0,000 0,04527773 0,05205622 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,04527773 0,05203101 ! excretion GO:0007588 72 46 0,000 0,04527773 0,05200583 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,04527773 0,05198067 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,04527773 0,05195553 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,04527773 0,05193042 ! positive regulation of defense response GO:0031349 70 47 0,000 0,04624005 0,05300852 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,04624005 0,05298293 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,04624005 0,05295736 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,04624005 0,05293181 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,04624005 0,05290629 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,04624005 0,05288079 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,04720145 0,05395426 ! viral infectious cycle GO:0019058 80 48 0,000 0,04720145 0,05392829 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,04720145 0,05390233 ! leukocyte migration GO:0050900 76 48 0,000 0,04720145 0,05387641 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,04720145 0,0538505 ! striated muscle contraction GO:0006941 78 48 0,000 0,04720145 0,05382463 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,04720145 0,05379878 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,04720145 0,05377295 ! tRNA processing GO:0008033 56 48 0,000 0,04720145 0,05374714 ! cell maturation GO:0048469 69 48 0,000 0,04720145 0,05372137 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,04720145 0,05369561 ! vesicle organization GO:0016050 87 48 0,000 0,04720145 0,05366988 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,04720145 0,05364418 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,04816194 0,05470956 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,04816194 0,05468338 ! glycolysis GO:0006096 63 49 0,000 0,04816194 0,05465723 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,04816194 0,05463111 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,04816194 0,054605 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,04816194 0,05457893 ! response to temperature stimulus GO:0009266 66 49 0,000 0,04816194 0,05455288 ! endocrine system development GO:0035270 86 49 0,000 0,04816194 0,05452685 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,04816194 0,05450085 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,04816194 0,05447487 ! gastrulation GO:0007369 80 49 0,000 0,04816194 0,05444892 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,04816194 0,05442299 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,04816194 0,05439708 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,04816194 0,05437121 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,04816194 0,05434535 ! methylation GO:0032259 74 49 0,000 0,04816194 0,05431952 ! cell redox homeostasis GO:0045454 72 50 0,000 0,0491215 0,05537545 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,0491215 0,05534915 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,0491215 0,05532288 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,0491215 0,05529664 ! histone modification GO:0016570 81 50 0,000 0,0491215 0,05527042 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,0491215 0,05524423 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,0491215 0,05521806 ! RNA catabolic process GO:0006401 77 51 0,000 0,05008014 0,05626902 ! chloride transport GO:0006821 78 51 0,000 0,05008014 0,05624239 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,05008014 0,05621579 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,05008014 0,05618921 ! regulation of ossification GO:0030278 82 51 0,000 0,05008014 0,05616265 ! heart morphogenesis GO:0003007 71 51 0,000 0,05008014 0,05613613 ! RNA elongation GO:0006354 67 51 0,000 0,05008014 0,05610962 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,05008014 0,05608314 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,05103787 0,05712871 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,05103787 0,05710177 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,05103787 0,05707486 ! regulation of DNA replication GO:0006275 88 52 0,000 0,05103787 0,05704798 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,05103787 0,05702112 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,05103787 0,05699429 ! covalent chromatin modification GO:0016569 90 52 0,000 0,05103787 0,05696748 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,05103787 0,0569407 ! proton transport GO:0015992 78 52 0,000 0,05103787 0,05691394 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,05103787 0,05688721 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,05103787 0,0568605 ! transition metal ion transport GO:0000041 88 53 0,000 0,05199468 0,05789928 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,05199468 0,05787212 ! muscle fiber development GO:0048747 80 53 0,000 0,05199468 0,05784499 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,05199468 0,05781788 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,05199468 0,0577908 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,05199468 0,05776375 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,05199468 0,05773672 ! regulation of endocytosis GO:0030100 71 53 0,000 0,05199468 0,05770971 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,05199468 0,05768273 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,05199468 0,05765578 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,05199468 0,05762885 ! maintenance of location GO:0051235 94 53 0,000 0,05199468 0,05760194 ! hydrogen transport GO:0006818 81 54 0,000 0,05295057 0,05863355 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,05295057 0,0586062 ! regulation of mitosis GO:0007088 91 54 0,000 0,05295057 0,05857888 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,05295057 0,05855158 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,05295057 0,05852431 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,05295057 0,05849706 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,05295057 0,05846984 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,05295057 0,05844265 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,05295057 0,05841548 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,05295057 0,05838833 ! germ cell development GO:0007281 82 54 0,000 0,05295057 0,05836121 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,05295057 0,05833412 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,05295057 0,05830705 ! establishment of organelle localization GO:0051656 91 54 0,000 0,05295057 0,05828001 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,05390554 0,05930359 ! ear development GO:0043583 83 55 0,000 0,05390554 0,05927611 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,05390554 0,05924866 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,05390554 0,05922123 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,05390554 0,05919382 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,05390554 0,05916644 ! regulation of actin filament length GO:0030832 88 56 0,000 0,0548596 0,06018578 ! positive regulation of secretion GO:0051047 83 56 0,000 0,0548596 0,06015797 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,0548596 0,06013018 ! DNA catabolic process GO:0006308 71 56 0,000 0,0548596 0,06010242 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,0548596 0,06007468 ! adult behavior GO:0030534 90 56 0,000 0,0548596 0,06004697 ! cartilage development GO:0051216 84 56 0,000 0,0548596 0,06001929 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,05581275 0,06103394 ! mesoderm development GO:0007498 84 57 0,000 0,05581275 0,06100583 ! aging GO:0007568 91 57 0,000 0,05581275 0,06097774 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,05581275 0,06094968 ! single fertilization GO:0007338 67 57 0,000 0,05581275 0,06092165 ! regulation of cellular component size GO:0032535 90 58 0,000 0,05676498 0,06193255 ! lipid modification GO:0030258 82 58 0,000 0,05676498 0,06190409 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,05676498 0,06187566 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,05676498 0,06184725 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,05771631 0,06285488 ! viral reproductive process GO:0022415 99 59 0,000 0,05771631 0,06282605 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,05771631 0,06279725 ! chromosome segregation GO:0007059 93 59 0,000 0,05771631 0,06276847 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,05771631 0,06273971 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,05771631 0,06271099 ! cell projection assembly GO:0030031 90 59 0,000 0,05771631 0,06268228 ! glucose catabolic process GO:0006007 78 60 0,000 0,05866671 0,06368532 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,05866671 0,0636562 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,05866671 0,06362711 ! kidney development GO:0001822 101 60 0,000 0,05866671 0,06359804 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,05866671 0,063569 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,05961621 0,06456836 ! carbohydrate transport GO:0008643 83 61 0,000 0,05961621 0,0645389 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,05961621 0,06450947 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,0605648 0,06550605 ! amino acid transport GO:0006865 97 62 0,000 0,0605648 0,06547621 ! activation of MAPK activity GO:0000187 95 62 0,000 0,0605648 0,06544639 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,0605648 0,0654166 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,0605648 0,06538684 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,0605648 0,06535711 ! detection of external stimulus GO:0009581 78 62 0,000 0,0605648 0,0653274 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,0605648 0,06529772 ! secondary metabolic process GO:0019748 95 62 0,000 0,0605648 0,06526806 ! gonad development GO:0008406 91 62 0,000 0,0605648 0,06523844 ! exocytosis GO:0006887 91 63 0,000 0,06151248 0,06622918 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,06151248 0,06619915 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,06151248 0,06616914 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,06151248 0,06613916 ! regulation of heart contraction GO:0008016 104 63 0,000 0,06151248 0,0661092 ! developmental maturation GO:0021700 90 63 0,000 0,06151248 0,06607928 ! actin filament organization GO:0007015 107 64 0,000 0,06245925 0,06706598 ! fertilization GO:0009566 79 64 0,000 0,06245925 0,06703565 ! viral reproduction GO:0016032 104 64 0,000 0,06245925 0,06700534 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,06245925 0,06697506 ! amine catabolic process GO:0009310 100 65 0,000 0,06340512 0,0679586 ! camera-type eye development GO:0043010 103 65 0,000 0,06340512 0,06792792 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,06340512 0,06789727 ! regulation of lipase activity GO:0060191 117 65 0,000 0,06340512 0,06786664 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,06340512 0,06783604 ! organelle localization GO:0051640 105 65 0,000 0,06340512 0,06780547 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,06435008 0,06878501 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,06435008 0,06875404 ! sensory perception of smell GO:0007608 81 66 0,000 0,06435008 0,0687231 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,06435008 0,06869219 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,06435008 0,0686613 ! lung development GO:0030324 112 66 0,000 0,06435008 0,06863044 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,06435008 0,06859961 ! B cell activation GO:0042113 119 66 0,000 0,06435008 0,06856881 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,06435008 0,06853803 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,06529413 0,06951232 ! neurotransmitter transport GO:0006836 92 67 0,000 0,06529413 0,06948115 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,06529413 0,06945001 ! appendage morphogenesis GO:0035107 103 67 0,000 0,06529413 0,06941889 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,06529413 0,0693878 ! extracellular matrix organization GO:0030198 117 67 0,000 0,06529413 0,06935674 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,06529413 0,06932571 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,06623728 0,07029564 ! defense response to bacterium GO:0042742 79 68 0,000 0,06623728 0,07026422 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,06623728 0,07023282 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,06623728 0,07020145 ! activation of immune response GO:0002253 93 68 0,000 0,06623728 0,07017011 ! appendage development GO:0048736 108 69 0,000 0,06717952 0,07113655 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,06717952 0,07110482 ! urogenital system development GO:0001655 114 69 0,000 0,06717952 0,07107312 ! hexose catabolic process GO:0019320 95 70 0,000 0,06812086 0,0720369 ! adaptive immune response GO:0002250 102 70 0,000 0,06812086 0,07200481 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,0690613 0,07296636 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,0690613 0,07293389 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,0690613 0,07290145 ! axon guidance GO:0007411 116 71 0,000 0,0690613 0,07286903 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,0690613 0,07283665 ! response to drug GO:0042493 115 72 0,000 0,07000083 0,07379475 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,07000083 0,07376198 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,07000083 0,07372924 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,07000083 0,07369653 ! respiratory system development GO:0060541 123 72 0,000 0,07000083 0,07366385 ! rhythmic process GO:0048511 113 72 0,000 0,07000083 0,07363119 ! regulation of immune effector process GO:0002697 121 72 0,000 0,07000083 0,07359857 ! learning or memory GO:0007611 132 73 0,000 0,07093947 0,07455241 ! humoral immune response GO:0006959 93 73 0,000 0,07093947 0,07451941 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,07093947 0,07448644 ! acute inflammatory response GO:0002526 107 74 0,000 0,0718772 0,07543768 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,0718772 0,07540433 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,0718772 0,07537101 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,0718772 0,07533772 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,0718772 0,07530446 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,0718772 0,07527123 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,07281404 0,07621866 ! inorganic anion transport GO:0015698 109 75 0,000 0,07281404 0,07618506 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,07281404 0,07615148 ! regulation of catabolic process GO:0009894 114 75 0,000 0,07281404 0,07611793 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,07374997 0,07706239 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,07374997 0,07702847 ! negative regulation of transport GO:0051051 122 77 0,000 0,07468501 0,07797076 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,07468501 0,07793647 ! response to nutrient GO:0007584 114 77 0,000 0,07468501 0,07790221 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,07468501 0,07786798 ! regulation of blood pressure GO:0008217 119 78 0,000 0,07561915 0,07880731 ! muscle cell differentiation GO:0042692 117 78 0,000 0,07561915 0,07877272 ! amine transport GO:0015837 115 78 0,000 0,07561915 0,07873815 ! antigen processing and presentation GO:0019882 114 78 0,000 0,07561915 0,07870362 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,0765524 0,07964 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,07748475 0,08057464 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,07748475 0,08053934 ! regulation of DNA binding GO:0051101 130 80 0,000 0,07748475 0,08050408 ! tube morphogenesis GO:0035239 140 80 0,000 0,07748475 0,08046885 ! eye development GO:0001654 130 80 0,000 0,07748475 0,08043365 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,07748475 0,08039848 ! protein ubiquitination GO:0016567 135 80 0,000 0,07748475 0,08036334 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,07748475 0,08032823 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,07748475 0,08029315 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,07748475 0,0802581 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,07748475 0,08022309 ! blood coagulation GO:0007596 129 81 0,000 0,07841621 0,08115206 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,07841621 0,08111668 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,07841621 0,08108134 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,07841621 0,08104602 ! response to hypoxia GO:0001666 155 81 0,000 0,07841621 0,08101074 ! regulation of protein transport GO:0051223 123 81 0,000 0,07841621 0,08097549 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,07934677 0,08190078 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,07934677 0,08186517 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,07934677 0,08182959 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,07934677 0,08179405 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,08027644 0,08271646 ! response to oxygen levels GO:0070482 160 83 0,000 0,08027644 0,08268056 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,08027644 0,08264469 ! regulation of lyase activity GO:0051339 147 83 0,000 0,08027644 0,08260885 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,08027644 0,08257304 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,08120522 0,0834922 ! digestion GO:0007586 111 84 0,000 0,08120522 0,08345604 ! regulation of neurological system process GO:0031644 133 84 0,000 0,08120522 0,08341991 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,08120522 0,08338381 ! cellular respiration GO:0045333 119 85 0,000 0,08213311 0,08430012 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,08213311 0,08426367 ! T cell activation GO:0042110 154 85 0,000 0,08213311 0,08422726 ! sex differentiation GO:0007548 126 85 0,000 0,08213311 0,08419087 ! protein import into nucleus GO:0006606 145 85 0,000 0,08213311 0,08415452 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,08213311 0,0841182 ! alcohol catabolic process GO:0046164 119 86 0,000 0,08306011 0,08503091 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,08306011 0,08499424 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,08398622 0,08590487 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,08398622 0,08586786 ! regulation of defense response GO:0031347 135 87 0,000 0,08398622 0,08583088 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,08398622 0,08579393 ! tRNA metabolic process GO:0006399 110 87 0,000 0,08398622 0,08575701 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,08398622 0,08572013 ! gland development GO:0048732 170 87 0,000 0,08398622 0,08568327 ! vitamin metabolic process GO:0006766 117 87 0,000 0,08398622 0,08564645 ! forebrain development GO:0030900 151 87 0,000 0,08398622 0,08560966 ! regulation of membrane potential GO:0042391 144 88 0,000 0,08491144 0,0865156 ! ossification GO:0001503 150 89 0,000 0,08583577 0,08741986 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,08583577 0,08738236 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,08675921 0,08828457 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,08675921 0,08824673 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,08675921 0,08820892 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,08675921 0,08817114 ! nuclear import GO:0051170 153 90 0,000 0,08675921 0,0881334 ! regulation of protein localization GO:0032880 141 90 0,000 0,08675921 0,08809569 ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,08768177 0,08899437 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,08768177 0,08895633 ! protein localization in nucleus GO:0034504 161 92 0,000 0,08860345 0,08985298 ! sterol metabolic process GO:0016125 136 92 0,000 0,08860345 0,0898146 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,08952424 0,09070923 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,08952424 0,09067051 ! rRNA processing GO:0006364 124 93 0,000 0,08952424 0,09063183 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,08952424 0,09059318 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,08952424 0,09055457 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,08952424 0,09051598 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,08952424 0,09047743 ! leukocyte differentiation GO:0002521 165 94 0,000 0,09044414 0,09136822 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,09044414 0,09132934 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,09044414 0,09129049 ! rRNA metabolic process GO:0016072 125 94 0,000 0,09044414 0,09125168 ! hormone metabolic process GO:0042445 135 94 0,000 0,09044414 0,0912129 ! protein processing GO:0016485 127 94 0,000 0,09044414 0,09117415 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,09136316 0,09206148 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,09136316 0,0920224 ! ATP metabolic process GO:0046034 150 96 0,000 0,0922813 0,09290773 ! nucleosome organization GO:0034728 126 96 0,000 0,0922813 0,09286833 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,0922813 0,09282896 ! female pregnancy GO:0007565 148 96 0,000 0,0922813 0,09278963 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,09319856 0,09367225 ! reproductive developmental process GO:0003006 149 97 0,000 0,09319856 0,09363259 ! response to virus GO:0009615 141 98 0,000 0,09411494 0,09451322 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,09411494 0,09447324 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,09411494 0,0944333 ! regulation of T cell activation GO:0050863 155 98 0,000 0,09411494 0,09439338 ! regulation of binding GO:0051098 164 99 0,000 0,09503043 0,09527132 ! electron transport chain GO:0022900 135 99 0,000 0,09503043 0,09523109 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,09503043 0,09519089 ! cell fate commitment GO:0045165 165 99 0,000 0,09503043 0,09515073 ! positive regulation of immune response GO:0050778 143 99 0,000 0,09503043 0,0951106 ! sulfur metabolic process GO:0006790 136 99 0,000 0,09503043 0,0950705 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,09594505 0,09594505