pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/7415-9-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 6,000 2,695E-12 6,584E-09 GO:0010498|proteasomal protein catabolic process, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 5,000 4,159E-11 5,08E-08 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 5,000 4,552E-11 3,707E-08 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 5,000 5,921E-11 3,616E-08 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 5,000 5,921E-11 2,893E-08 ! positive regulation of ligase activity GO:0051351 130 77 5,000 8,956E-11 3,647E-08 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 5,000 1,049E-10 3,66E-08 ! regulation of ligase activity GO:0051340 147 84 5,000 1,528E-10 4,668E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 2,032E-09 5,516E-07 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 3,000 4,527E-07 1,106E-04 ! negative regulation of ligase activity GO:0051352 116 68 3,000 4,807E-07 1,067E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cellular response to unfolded protein GO:0034620 35 20 2,000 8,222E-07 1,674E-04 GO:0030968|endoplasmic reticulum unfolded protein response, ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 1,654E-06 3,108E-04 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,868E-06 3,26E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 2,091E-06 3,405E-04 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,62E-06 4,001E-04 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 1,000 8,344E-06 1,199E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,077E-05 1,462E-03 ! response to UV GO:0009411 120 55 2,000 1,851E-05 2,38E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,332E-05 2,849E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,744E-05 4,356E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,744E-05 4,158E-03 ! phosphate transport GO:0006817 24 10 1,000 3,744E-05 3,977E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 5,485E-05 5,583E-03 ! response to unfolded protein GO:0006986 139 90 2,000 8,106E-05 7,921E-03 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 8,711E-05 8,185E-03 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! response to protein stimulus GO:0051789 158 96 2,000 9,822E-05 8,887E-03 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,127E-04 9,832E-03 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,267E-04 0,01067383 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,909E-04 0,01554204 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 2,089E-04 0,01646357 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,278E-04 0,01738889 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,278E-04 0,01686195 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,474E-04 0,01777881 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,679E-04 0,01869922 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,112E-04 0,02111995 ! fat cell differentiation GO:0045444 57 28 1,000 3,112E-04 0,02054914 ! regulation of B cell activation GO:0050864 55 30 1,000 3,577E-04 0,02299878 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,822E-04 0,02394061 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 3,822E-04 0,02334209 ! spindle organization GO:0007051 50 32 1,000 4,074E-04 0,02427685 ! regulation of microtubule-based process GO:0032886 86 37 1,000 5,455E-04 0,03172916 ! meiosis I GO:0007127 74 38 1,000 5,755E-04 0,03269403 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 5,755E-04 0,03195098 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 6,062E-04 0,03291055 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 7,717E-04 0,04098286 ! double-strand break repair GO:0006302 85 44 1,000 7,717E-04 0,04011088 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 8,071E-04 0,04107815 ! positive regulation of cell cycle GO:0045787 96 48 1,000 9,18E-04 0,04576925 ! response to calcium ion GO:0051592 94 49 1,000 9,565E-04 0,04673542 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 9,565E-04 0,04581904 ! activation of caspase activity GO:0006919 95 50 1,000 9,958E-04 0,04678316 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 1,077E-03 0,04962729 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,118E-03 0,05058904 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 1,248E-03 0,05541192 ! regulation of protein catabolic process GO:0042176 126 56 1,000 1,248E-03 0,05442242 ! positive regulation of caspase activity GO:0043280 108 57 1,000 1,292E-03 0,05537979 GO:0010952|positive regulation of peptidase activity, ! negative regulation of cell growth GO:0030308 142 67 1,000 1,78E-03 0,07496108 ! negative regulation of cell size GO:0045792 144 69 1,000 1,886E-03 0,07809938 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 1,886E-03 0,07679773 ! negative regulation of kinase activity GO:0033673 145 70 1,000 1,94E-03 0,07771542 ! regulation of caspase activity GO:0043281 136 74 1,000 2,165E-03 0,08531905 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 2,165E-03 0,08396478 ! negative regulation of transferase activity GO:0051348 155 74 1,000 2,165E-03 0,08265283 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 2,223E-03 0,08356244 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 2,342E-03 0,08667395 ! regulation of catabolic process GO:0009894 173 77 1,000 2,342E-03 0,08538031 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 2,402E-03 0,08628852 ! negative regulation of organelle organization GO:0010639 181 80 1,000 2,524E-03 0,08938021 ! meiosis GO:0007126 143 81 1,000 2,587E-03 0,09028151 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 2,587E-03 0,08900994 ! regulation of peptidase activity GO:0052547 150 82 1,000 2,65E-03 0,08991593 ! meiotic cell cycle GO:0051321 144 82 1,000 2,65E-03 0,08868421 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 2,714E-03 0,089594 GO:0045937|positive regulation of phosphate metabolic process, ! inorganic anion transport GO:0015698 156 83 1,000 2,714E-03 0,08839942 ! response to metal ion GO:0010038 158 84 1,000 2,778E-03 0,08931224 ! negative regulation of growth GO:0045926 168 85 1,000 2,844E-03 0,09022422 ! positive regulation of cell activation GO:0050867 161 86 1,000 2,91E-03 0,09113536 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 173 90 1,000 3,181E-03 0,09837023 ! positive regulation of protein modification process GO:0031401 156 90 1,000 3,181E-03 0,0971406 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 4,634E-03 0,13975716 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 4,634E-03 0,1380528 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 4,634E-03 0,13638952 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,634E-03 0,13476583 ! positive regulation of helicase activity GO:0051096 12 5 0,000 4,634E-03 0,13318035 ! neuron fate determination GO:0048664 7 5 0,000 4,634E-03 0,13163174 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,634E-03 0,13011873 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 4,634E-03 0,12864011 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 4,634E-03 0,12719472 ! polyol transport GO:0015791 12 5 0,000 4,634E-03 0,12578144 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,634E-03 0,12439923 ! response to superoxide GO:0000303 10 5 0,000 4,634E-03 0,12304706 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,634E-03 0,12172398 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 4,634E-03 0,12042904 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 4,634E-03 0,11916137 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,634E-03 0,1179201 ! female meiosis GO:0007143 10 5 0,000 4,634E-03 0,11670443 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,634E-03 0,11551357 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,634E-03 0,11434677 ! hypothalamus development GO:0021854 9 5 0,000 4,634E-03 0,1132033 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 4,634E-03 0,11208247 ! cobalt ion transport GO:0006824 11 5 0,000 4,634E-03 0,11098363 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 4,634E-03 0,10990612 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 4,634E-03 0,10884933 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,634E-03 0,10781267 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,634E-03 0,10679556 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 4,634E-03 0,10579748 ! embryonic camera-type eye development GO:0031076 12 5 0,000 4,634E-03 0,10481787 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,634E-03 0,10385624 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,634E-03 0,10291209 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 4,634E-03 0,10198495 ! transposition GO:0032196 9 5 0,000 4,634E-03 0,10107437 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 4,634E-03 0,10017991 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 4,634E-03 0,09930114 ! negative chemotaxis GO:0050919 16 5 0,000 4,634E-03 0,09843765 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,634E-03 0,09758905 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,634E-03 0,09675496 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 4,634E-03 0,095935 ! behavioral response to pain GO:0048266 10 5 0,000 4,634E-03 0,09512882 ! clathrin coat assembly GO:0048268 15 5 0,000 4,634E-03 0,09433608 ! Notch receptor processing GO:0007220 11 5 0,000 4,634E-03 0,09355645 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,634E-03 0,09278959 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 4,634E-03 0,0920352 ! micturition GO:0060073 9 5 0,000 4,634E-03 0,09129298 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,634E-03 0,09056264 ! copulation GO:0007620 9 5 0,000 4,634E-03 0,08984389 ! glial cell fate commitment GO:0021781 14 5 0,000 4,634E-03 0,08913646 ! protein maturation by protein folding GO:0022417 14 5 0,000 4,634E-03 0,08844008 ! bioluminescence GO:0008218 9 5 0,000 4,634E-03 0,0877545 ! spermidine metabolic process GO:0008216 7 5 0,000 4,634E-03 0,08707946 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,634E-03 0,08641473 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,634E-03 0,08576007 ! apoptotic cell clearance GO:0043277 23 5 0,000 4,634E-03 0,08511526 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,634E-03 0,08448007 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 4,634E-03 0,0838543 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,634E-03 0,08323772 ! grooming behavior GO:0007625 6 5 0,000 4,634E-03 0,08263015 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 4,634E-03 0,08203138 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,634E-03 0,08144122 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 4,634E-03 0,0808595 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,634E-03 0,08028603 ! response to protozoan GO:0001562 13 5 0,000 4,634E-03 0,07972063 ! positive regulation of glycolysis GO:0045821 13 5 0,000 4,634E-03 0,07916315 ! lymph vessel development GO:0001945 10 5 0,000 4,634E-03 0,0786134 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 4,634E-03 0,07807124 ! endochondral ossification GO:0001958 17 5 0,000 4,634E-03 0,07753651 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,634E-03 0,07700905 ! single strand break repair GO:0000012 8 5 0,000 4,634E-03 0,07648872 ! parathyroid gland development GO:0060017 14 5 0,000 4,634E-03 0,07597537 ! anagen GO:0042640 7 5 0,000 4,634E-03 0,07546887 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,634E-03 0,07496907 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,634E-03 0,07447585 ! cytokine secretion GO:0050663 15 5 0,000 4,634E-03 0,07398908 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 4,634E-03 0,07350864 ! ceramide catabolic process GO:0046514 7 5 0,000 4,634E-03 0,07303439 ! skeletal myofibril assembly GO:0014866 12 5 0,000 4,634E-03 0,07256622 ! smooth muscle tissue development GO:0048745 32 5 0,000 4,634E-03 0,07210401 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,634E-03 0,07164766 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,634E-03 0,07119704 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,634E-03 0,07075206 ! cardiac muscle fiber development GO:0048739 12 5 0,000 4,634E-03 0,07031261 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,634E-03 0,06987858 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 4,634E-03 0,06944988 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,634E-03 0,0690264 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 4,634E-03 0,06860806 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,634E-03 0,06819476 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,634E-03 0,06778641 ! glycine biosynthetic process GO:0006545 7 5 0,000 4,634E-03 0,06738292 ! microvillus organization GO:0032528 8 5 0,000 4,634E-03 0,0669842 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 4,634E-03 0,06659018 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 4,634E-03 0,06620076 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 4,634E-03 0,06581587 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 4,634E-03 0,06543543 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 4,634E-03 0,06505937 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 4,634E-03 0,0646876 ! polyol catabolic process GO:0046174 9 5 0,000 4,634E-03 0,06432006 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,634E-03 0,06395667 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 4,634E-03 0,06359736 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,634E-03 0,06324207 ! muscle cell migration GO:0014812 8 5 0,000 4,634E-03 0,06289072 ! mitochondrial fission GO:0000266 8 5 0,000 4,634E-03 0,06254326 ! sister chromatid cohesion GO:0007062 15 5 0,000 4,634E-03 0,06219961 ! response to tumor necrosis factor GO:0034612 10 5 0,000 4,634E-03 0,06185973 ! mRNA transcription GO:0009299 10 5 0,000 4,634E-03 0,06152353 ! nerve growth factor processing GO:0032455 9 5 0,000 4,634E-03 0,06119097 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 4,634E-03 0,06086199 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 4,634E-03 0,06053652 ! anaerobic glycolysis GO:0019642 6 5 0,000 4,634E-03 0,06021452 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,634E-03 0,05989593 ! monocyte activation GO:0042117 10 5 0,000 4,634E-03 0,05958068 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,634E-03 0,05926874 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,634E-03 0,05896005 ! response to food GO:0032094 6 5 0,000 4,634E-03 0,05865456 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,634E-03 0,05835222 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,634E-03 0,05805297 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 4,634E-03 0,05775679 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,634E-03 0,0574636 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 4,634E-03 0,05717338 ! forebrain neuron development GO:0021884 13 5 0,000 4,634E-03 0,05688608 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,634E-03 0,05660165 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 4,634E-03 0,05632005 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 4,634E-03 0,05604124 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,634E-03 0,05576517 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,634E-03 0,05549181 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 4,634E-03 0,05522112 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,634E-03 0,05495306 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 4,634E-03 0,05468758 ! lipid glycosylation GO:0030259 7 5 0,000 4,634E-03 0,05442466 ! nucleobase transport GO:0015851 6 5 0,000 4,634E-03 0,05416426 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,634E-03 0,05390633 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 4,634E-03 0,05365085 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 4,634E-03 0,05339778 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 4,634E-03 0,05314709 ! basic amino acid transport GO:0015802 12 5 0,000 4,634E-03 0,05289874 ! cellular glucose homeostasis GO:0001678 6 5 0,000 4,634E-03 0,0526527 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 4,634E-03 0,05240893 ! actin nucleation GO:0045010 11 5 0,000 4,634E-03 0,05216742 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,634E-03 0,05192812 ! depurination GO:0045007 5 5 0,000 4,634E-03 0,051691 ! depyrimidination GO:0045008 10 5 0,000 4,634E-03 0,05145604 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,634E-03 0,05122321 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,634E-03 0,05099248 ! G2/M transition checkpoint GO:0031576 8 5 0,000 4,634E-03 0,05076381 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,634E-03 0,05053719 ! zinc ion homeostasis GO:0055069 9 5 0,000 4,634E-03 0,05031258 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 4,634E-03 0,05008996 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 4,634E-03 0,04986929 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,634E-03 0,04965057 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,634E-03 0,04943375 ! activated T cell proliferation GO:0050798 16 5 0,000 4,634E-03 0,04921883 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,634E-03 0,04900576 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 4,634E-03 0,04879453 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,634E-03 0,04858511 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,634E-03 0,04837748 ! gamma-delta T cell activation GO:0046629 6 5 0,000 4,634E-03 0,04817162 ! response to arsenic GO:0046685 11 5 0,000 4,634E-03 0,0479675 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 4,634E-03 0,04776511 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,634E-03 0,04756441 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 4,634E-03 0,0473654 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 4,634E-03 0,04716804 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 4,634E-03 0,04697232 ! response to mercury ion GO:0046689 8 5 0,000 4,634E-03 0,04677822 ! response to cadmium ion GO:0046686 7 5 0,000 4,634E-03 0,04658572 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 4,634E-03 0,04639479 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 4,634E-03 0,04620543 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 4,634E-03 0,0460176 ! bile acid biosynthetic process GO:0006699 7 5 0,000 4,634E-03 0,0458313 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,634E-03 0,04564649 ! ganglioside catabolic process GO:0006689 12 5 0,000 4,634E-03 0,04546317 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,634E-03 0,04528132 ! decidualization GO:0046697 11 5 0,000 4,634E-03 0,04510092 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 4,634E-03 0,04492194 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 4,634E-03 0,04474439 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 4,634E-03 0,04456823 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 4,634E-03 0,04439345 ! embryonic cleavage GO:0040016 6 5 0,000 4,634E-03 0,04422004 ! peroxisome fission GO:0016559 5 5 0,000 4,634E-03 0,04404798 ! histone demethylation GO:0016577 13 5 0,000 4,634E-03 0,04387725 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 4,634E-03 0,04370784 ! mitotic recombination GO:0006312 9 5 0,000 4,634E-03 0,04353973 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 4,634E-03 0,04337291 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,634E-03 0,04320737 ! metaphase plate congression GO:0051310 7 5 0,000 4,634E-03 0,04304308 ! regulation of sterol transport GO:0032371 7 5 0,000 4,634E-03 0,04288004 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,634E-03 0,04271823 ! enteric nervous system development GO:0048484 8 5 0,000 4,634E-03 0,04255763 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 4,634E-03 0,04239824 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 4,634E-03 0,04224004 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 4,634E-03 0,04208301 ! muscle cell proliferation GO:0033002 12 5 0,000 4,634E-03 0,04192715 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,634E-03 0,04177244 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 4,634E-03 0,04161886 ! B cell homeostasis GO:0001782 13 5 0,000 4,634E-03 0,04146641 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 4,634E-03 0,04131507 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,634E-03 0,04116484 ! metaphase GO:0051323 11 5 0,000 4,634E-03 0,04101569 ! melatonin biosynthetic process GO:0030187 7 5 0,000 4,634E-03 0,04086762 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 4,634E-03 0,04072061 ! cellular response to nutrient GO:0031670 8 5 0,000 4,634E-03 0,04057466 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,634E-03 0,04042975 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 4,634E-03 0,04028587 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 4,634E-03 0,04014301 ! regulation of hair follicle development GO:0051797 10 5 0,000 4,634E-03 0,04000117 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 4,634E-03 0,03986032 ! response to redox state GO:0051775 6 5 0,000 4,634E-03 0,03972046 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 4,634E-03 0,03958157 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 4,634E-03 0,03944366 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,634E-03 0,0393067 ! brown fat cell differentiation GO:0050873 7 5 0,000 4,634E-03 0,03917069 ! regulation of telomerase activity GO:0051972 7 5 0,000 4,634E-03 0,03903562 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,634E-03 0,03890148 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 4,634E-03 0,03876825 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,634E-03 0,03863594 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 4,634E-03 0,03850452 ! striatum development GO:0021756 14 5 0,000 4,634E-03 0,038374 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 4,634E-03 0,03824436 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,634E-03 0,03811559 ! glial cell migration GO:0008347 10 5 0,000 4,634E-03 0,03798768 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,634E-03 0,03786064 ! neural plate morphogenesis GO:0001839 7 5 0,000 4,634E-03 0,03773443 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 4,634E-03 0,03760907 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,634E-03 0,03748454 ! T cell activation during immune response GO:0002286 9 5 0,000 4,634E-03 0,03736082 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,634E-03 0,03723793 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,634E-03 0,03711584 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 4,634E-03 0,03699454 ! neuroprotection GO:0043526 8 5 0,000 4,634E-03 0,03687404 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,634E-03 0,03675432 ! regulation of sensory perception GO:0051931 8 5 0,000 4,634E-03 0,03663537 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,634E-03 0,03651719 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,634E-03 0,03639977 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 4,634E-03 0,03628311 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 4,634E-03 0,03616719 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,634E-03 0,03605201 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 4,634E-03 0,03593756 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,634E-03 0,03582383 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 4,634E-03 0,03571082 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 4,634E-03 0,03559852 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 4,634E-03 0,03548693 GO:0060119|inner ear receptor cell development, ! spindle assembly GO:0051225 6 5 0,000 4,634E-03 0,03537603 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,634E-03 0,03526583 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,634E-03 0,0351563 ! protein palmitoylation GO:0018345 12 5 0,000 4,634E-03 0,03504746 ! drug metabolic process GO:0017144 7 5 0,000 4,634E-03 0,03493929 ! stem cell division GO:0017145 11 5 0,000 4,634E-03 0,03483178 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,634E-03 0,03472494 ! organ regeneration GO:0031100 7 5 0,000 4,634E-03 0,03461875 ! carnitine metabolic process GO:0009437 8 5 0,000 4,634E-03 0,0345132 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,634E-03 0,0344083 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,558E-03 0,04114631 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,558E-03 0,04102201 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 5,558E-03 0,04089845 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 5,558E-03 0,04077563 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,558E-03 0,04065354 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 5,558E-03 0,04053219 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 5,558E-03 0,04041156 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,558E-03 0,04029164 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 5,558E-03 0,04017244 ! response to oxygen radical GO:0000305 11 6 0,000 5,558E-03 0,04005393 ! positive regulation of axon extension GO:0045773 13 6 0,000 5,558E-03 0,03993613 ! myoblast cell fate commitment GO:0048625 18 6 0,000 5,558E-03 0,03981901 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 5,558E-03 0,03970258 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 5,558E-03 0,03958683 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,558E-03 0,03947176 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,558E-03 0,03935734 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 5,558E-03 0,0392436 ! forebrain regionalization GO:0021871 9 6 0,000 5,558E-03 0,0391305 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,558E-03 0,03901806 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,558E-03 0,03890626 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 5,558E-03 0,0387951 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,558E-03 0,03868457 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 5,558E-03 0,03857467 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 5,558E-03 0,03846539 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,558E-03 0,03835673 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 5,558E-03 0,03824869 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 5,558E-03 0,03814125 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,558E-03 0,03803441 ! malate metabolic process GO:0006108 13 6 0,000 5,558E-03 0,03792817 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 5,558E-03 0,03782252 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 5,558E-03 0,03771746 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 5,558E-03 0,03761297 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 5,558E-03 0,03750907 ! protein refolding GO:0042026 15 6 0,000 5,558E-03 0,03740574 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,558E-03 0,03730298 ! opsonization GO:0008228 8 6 0,000 5,558E-03 0,03720078 ! mating behavior GO:0007617 7 6 0,000 5,558E-03 0,03709914 ! erythrocyte maturation GO:0043249 8 6 0,000 5,558E-03 0,03699805 ! embryonic hemopoiesis GO:0035162 16 6 0,000 5,558E-03 0,03689751 ! protein amino acid dealkylation GO:0008214 15 6 0,000 5,558E-03 0,03679752 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 5,558E-03 0,03669806 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 5,558E-03 0,03659915 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,558E-03 0,03650076 ! response to interferon-gamma GO:0034341 16 6 0,000 5,558E-03 0,03640291 ! toxin metabolic process GO:0009404 11 6 0,000 5,558E-03 0,03630557 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,558E-03 0,03620876 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 5,558E-03 0,03611246 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 5,558E-03 0,03601667 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 5,558E-03 0,03592139 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 5,558E-03 0,03582661 ! cGMP-mediated signaling GO:0019934 14 6 0,000 5,558E-03 0,03573233 ! dorsal spinal cord development GO:0021516 10 6 0,000 5,558E-03 0,03563854 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,558E-03 0,03554525 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 5,558E-03 0,03545244 ! thymic T cell selection GO:0045061 16 6 0,000 5,558E-03 0,03536011 ! sphingoid catabolic process GO:0046521 8 6 0,000 5,558E-03 0,03526827 ! protein lipoylation GO:0009249 10 6 0,000 5,558E-03 0,0351769 ! transepithelial chloride transport GO:0030321 12 6 0,000 5,558E-03 0,03508601 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 5,558E-03 0,03499558 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,558E-03 0,03490561 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 5,558E-03 0,03481611 ! glutamate catabolic process GO:0006538 12 6 0,000 5,558E-03 0,03472707 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 5,558E-03 0,03463848 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,558E-03 0,03455034 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 5,558E-03 0,03446265 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,558E-03 0,0343754 ! hyperosmotic response GO:0006972 10 6 0,000 5,558E-03 0,0342886 ! L-serine biosynthetic process GO:0006564 7 6 0,000 5,558E-03 0,03420223 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 5,558E-03 0,03411629 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 5,558E-03 0,03403079 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,558E-03 0,03394571 ! urea metabolic process GO:0019627 7 6 0,000 5,558E-03 0,03386106 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,558E-03 0,03377683 ! neutrophil activation GO:0042119 7 6 0,000 5,558E-03 0,03369301 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,558E-03 0,03360961 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 5,558E-03 0,03352663 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,558E-03 0,03344405 ! paraxial mesoderm development GO:0048339 16 6 0,000 5,558E-03 0,03336188 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 5,558E-03 0,03328011 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,558E-03 0,03319874 ! neuron apoptosis GO:0051402 15 6 0,000 5,558E-03 0,03311777 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,558E-03 0,03303719 ! T cell mediated immunity GO:0002456 17 6 0,000 5,558E-03 0,032957 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,558E-03 0,0328772 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 5,558E-03 0,03279779 ! carnitine transport GO:0015879 10 6 0,000 5,558E-03 0,03271876 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,558E-03 0,03264011 ! positive regulation of exocytosis GO:0045921 11 6 0,000 5,558E-03 0,03256183 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 5,558E-03 0,03248393 ! early endosome to late endosome transport GO:0045022 16 6 0,000 5,558E-03 0,03240641 ! 5S class rRNA transcription GO:0042791 13 6 0,000 5,558E-03 0,03232925 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,558E-03 0,03225246 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 5,558E-03 0,03217603 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 5,558E-03 0,03209996 ! sodium ion homeostasis GO:0055078 12 6 0,000 5,558E-03 0,03202425 ! establishment of spindle localization GO:0051293 16 6 0,000 5,558E-03 0,0319489 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 5,558E-03 0,03187391 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,558E-03 0,03179926 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 5,558E-03 0,03172496 ! response to UV-C GO:0010225 14 6 0,000 5,558E-03 0,03165101 ! astrocyte development GO:0014002 16 6 0,000 5,558E-03 0,0315774 ! protein targeting to lysosome GO:0006622 12 6 0,000 5,558E-03 0,03150414 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,558E-03 0,03143121 ! interaction with symbiont GO:0051702 14 6 0,000 5,558E-03 0,03135862 ! regulation of dendrite development GO:0050773 16 6 0,000 5,558E-03 0,03128637 ! peptidyl-arginine modification GO:0018195 13 6 0,000 5,558E-03 0,03121445 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 5,558E-03 0,03114285 ! response to copper ion GO:0046688 10 6 0,000 5,558E-03 0,03107159 ! response to exogenous dsRNA GO:0043330 13 6 0,000 5,558E-03 0,03100065 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 5,558E-03 0,03093003 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,558E-03 0,03085974 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 5,558E-03 0,03078976 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,558E-03 0,0307201 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 5,558E-03 0,03065075 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,558E-03 0,03058172 ! nucleoside catabolic process GO:0009164 10 6 0,000 5,558E-03 0,030513 ! hair follicle maturation GO:0048820 8 6 0,000 5,558E-03 0,03044458 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,558E-03 0,03037647 ! Schwann cell development GO:0014044 15 6 0,000 5,558E-03 0,03030867 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 5,558E-03 0,03024117 ! response to pheromone GO:0019236 6 6 0,000 5,558E-03 0,03017396 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 5,558E-03 0,03010706 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 5,558E-03 0,03004045 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 5,558E-03 0,02997414 ! base conversion or substitution editing GO:0016553 6 6 0,000 5,558E-03 0,02990811 ! subpallium development GO:0021544 15 6 0,000 5,558E-03 0,02984238 ! neural tube patterning GO:0021532 8 6 0,000 5,558E-03 0,02977694 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 5,558E-03 0,02971178 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 5,558E-03 0,02964691 ! maintenance of organ identity GO:0048496 9 6 0,000 5,558E-03 0,02958232 ! G2 phase GO:0051319 16 6 0,000 5,558E-03 0,02951801 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 5,558E-03 0,02945398 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 5,558E-03 0,02939022 ! oxygen homeostasis GO:0032364 10 6 0,000 5,558E-03 0,02932675 ! establishment of planar polarity GO:0001736 7 6 0,000 5,558E-03 0,02926354 ! regulation of mast cell activation GO:0033003 13 6 0,000 5,558E-03 0,02920061 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,558E-03 0,02913795 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 5,558E-03 0,02907555 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,558E-03 0,02901343 ! receptor internalization GO:0031623 11 6 0,000 5,558E-03 0,02895156 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 5,558E-03 0,02888997 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 5,558E-03 0,02882863 ! neutrophil homeostasis GO:0001780 11 6 0,000 5,558E-03 0,02876755 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,558E-03 0,02870673 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 5,558E-03 0,02864617 ! protein deubiquitination GO:0016579 16 6 0,000 5,558E-03 0,02858586 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 5,558E-03 0,02852581 ! protein destabilization GO:0031648 9 6 0,000 5,558E-03 0,028466 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 5,558E-03 0,02840645 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,558E-03 0,02834715 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 5,558E-03 0,02828809 ! regulation of viral transcription GO:0046782 11 6 0,000 5,558E-03 0,02822928 ! progesterone metabolic process GO:0042448 12 6 0,000 5,558E-03 0,02817071 ! negative regulation of axon extension GO:0030517 24 6 0,000 5,558E-03 0,02811239 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 5,558E-03 0,02805431 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 5,558E-03 0,02799646 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,558E-03 0,02793886 ! determination of adult lifespan GO:0008340 17 6 0,000 5,558E-03 0,02788149 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 5,558E-03 0,02782435 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 5,558E-03 0,02776745 ! neural plate development GO:0001840 9 6 0,000 5,558E-03 0,02771078 ! catecholamine transport GO:0051937 9 6 0,000 5,558E-03 0,02765435 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 5,558E-03 0,02759814 ! sensory cilium assembly GO:0035058 10 6 0,000 5,558E-03 0,02754216 ! organ or tissue specific immune response GO:0002251 8 6 0,000 5,558E-03 0,0274864 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 5,558E-03 0,02743088 ! maternal placenta development GO:0001893 12 6 0,000 5,558E-03 0,02737557 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 5,558E-03 0,02732049 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,558E-03 0,02726563 ! negative regulation of B cell activation GO:0050869 14 6 0,000 5,558E-03 0,02721099 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 5,558E-03 0,02715657 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 5,558E-03 0,02710236 ! positive regulation of coagulation GO:0050820 13 6 0,000 5,558E-03 0,02704837 ! cellular anion homeostasis GO:0030002 11 6 0,000 5,558E-03 0,0269946 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 6,481E-03 0,03141707 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 6,481E-03 0,03135486 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 6,481E-03 0,03129289 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,481E-03 0,03123117 ! regulation of helicase activity GO:0051095 16 7 0,000 6,481E-03 0,03116969 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 6,481E-03 0,03110846 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 6,481E-03 0,03104746 ! sleep GO:0030431 16 7 0,000 6,481E-03 0,0309867 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,481E-03 0,03092618 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 6,481E-03 0,0308659 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,481E-03 0,03080585 ! prostate gland development GO:0030850 14 7 0,000 6,481E-03 0,03074603 ! nucleotide-sugar transport GO:0015780 11 7 0,000 6,481E-03 0,03068644 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,481E-03 0,03062709 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,481E-03 0,03056796 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 6,481E-03 0,03050907 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,481E-03 0,03045039 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 6,481E-03 0,03039195 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 6,481E-03 0,03033373 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,481E-03 0,03027573 ! SMAD protein complex assembly GO:0007183 13 7 0,000 6,481E-03 0,03021795 ! glycolipid transport GO:0046836 11 7 0,000 6,481E-03 0,03016039 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,481E-03 0,03010305 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,481E-03 0,03004593 ! neuron adhesion GO:0007158 14 7 0,000 6,481E-03 0,02998902 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 6,481E-03 0,02993233 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,481E-03 0,02987586 ! establishment of tissue polarity GO:0007164 8 7 0,000 6,481E-03 0,02981959 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 6,481E-03 0,02976354 ! mRNA stabilization GO:0048255 18 7 0,000 6,481E-03 0,0297077 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 6,481E-03 0,02965207 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 6,481E-03 0,02959664 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 6,481E-03 0,02954143 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 6,481E-03 0,02948641 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 6,481E-03 0,02943161 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,481E-03 0,029377 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,481E-03 0,0293226 ! lipoprotein transport GO:0042953 14 7 0,000 6,481E-03 0,0292684 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 6,481E-03 0,0292144 ! rhythmic behavior GO:0007622 17 7 0,000 6,481E-03 0,0291606 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 6,481E-03 0,02910699 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 6,481E-03 0,02905359 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 6,481E-03 0,02900038 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 6,481E-03 0,02894736 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,481E-03 0,02889453 ! regulation of odontogenesis GO:0042481 14 7 0,000 6,481E-03 0,0288419 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,481E-03 0,02878946 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 6,481E-03 0,02873721 ! mechanosensory behavior GO:0007638 16 7 0,000 6,481E-03 0,02868515 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 6,481E-03 0,02863328 ! positive regulation of isotype switching GO:0045830 17 7 0,000 6,481E-03 0,0285816 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 6,481E-03 0,0285301 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 6,481E-03 0,02847879 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,481E-03 0,02842766 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,481E-03 0,02837671 ! spinal cord patterning GO:0021511 14 7 0,000 6,481E-03 0,02832595 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 6,481E-03 0,02827537 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 6,481E-03 0,02822496 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,481E-03 0,02817474 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 6,481E-03 0,0281247 ! adrenal gland development GO:0030325 17 7 0,000 6,481E-03 0,02807483 ! cysteine metabolic process GO:0006534 13 7 0,000 6,481E-03 0,02802514 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 6,481E-03 0,02797563 ! ovulation GO:0030728 10 7 0,000 6,481E-03 0,02792629 ! adenohypophysis development GO:0021984 11 7 0,000 6,481E-03 0,02787712 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 6,481E-03 0,02782813 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 6,481E-03 0,02777931 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 6,481E-03 0,02773066 ! microtubule nucleation GO:0007020 21 7 0,000 6,481E-03 0,02768218 ! proline biosynthetic process GO:0006561 10 7 0,000 6,481E-03 0,02763387 ! tryptophan metabolic process GO:0006568 11 7 0,000 6,481E-03 0,02758572 ! thyroid hormone generation GO:0006590 13 7 0,000 6,481E-03 0,02753775 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 6,481E-03 0,02748994 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 6,481E-03 0,0274423 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,481E-03 0,02739482 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 6,481E-03 0,0273475 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 6,481E-03 0,02730035 ! galactose metabolic process GO:0006012 13 7 0,000 6,481E-03 0,02725336 ! vesicle fusion GO:0006906 20 7 0,000 6,481E-03 0,02720654 ! response to dietary excess GO:0002021 8 7 0,000 6,481E-03 0,02715987 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,481E-03 0,02711336 ! intracellular pH reduction GO:0051452 13 7 0,000 6,481E-03 0,02706702 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,481E-03 0,02702083 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 6,481E-03 0,0269748 ! organ growth GO:0035265 15 7 0,000 6,481E-03 0,02692892 ! nucleoside transport GO:0015858 11 7 0,000 6,481E-03 0,0268832 ! nucleoside salvage GO:0043174 11 7 0,000 6,481E-03 0,02683764 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 6,481E-03 0,02679222 ! male sex determination GO:0030238 15 7 0,000 6,481E-03 0,02674697 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 6,481E-03 0,02670186 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 6,481E-03 0,02665691 ! parturition GO:0007567 16 7 0,000 6,481E-03 0,02661211 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 6,481E-03 0,02656746 ! rRNA modification GO:0000154 14 7 0,000 6,481E-03 0,02652296 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 6,481E-03 0,0264786 ! spindle checkpoint GO:0031577 16 7 0,000 6,481E-03 0,0264344 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 6,481E-03 0,02639034 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 6,481E-03 0,02634643 ! monocyte differentiation GO:0030224 16 7 0,000 6,481E-03 0,02630267 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 6,481E-03 0,02625905 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,481E-03 0,02621557 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 6,481E-03 0,02617224 ! hyaluronan metabolic process GO:0030212 9 7 0,000 6,481E-03 0,02612905 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 6,481E-03 0,026086 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,481E-03 0,0260431 ! fibrinolysis GO:0042730 11 7 0,000 6,481E-03 0,02600034 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 6,481E-03 0,02595771 ! skeletal muscle contraction GO:0003009 8 7 0,000 6,481E-03 0,02591523 ! eating behavior GO:0042755 8 7 0,000 6,481E-03 0,02587288 ! B cell lineage commitment GO:0002326 21 7 0,000 6,481E-03 0,02583068 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,481E-03 0,02578861 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 6,481E-03 0,02574667 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 6,481E-03 0,02570488 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,481E-03 0,02566322 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 6,481E-03 0,02562169 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,481E-03 0,0255803 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 6,481E-03 0,02553904 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 6,481E-03 0,02549791 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 6,481E-03 0,02545692 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 6,481E-03 0,02541606 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,481E-03 0,02537533 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 6,481E-03 0,02533473 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,481E-03 0,02529426 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,481E-03 0,02525392 ! histone ubiquitination GO:0016574 9 7 0,000 6,481E-03 0,0252137 ! regulation of meiosis GO:0040020 12 7 0,000 6,481E-03 0,02517362 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 6,481E-03 0,02513366 ! T cell lineage commitment GO:0002360 16 7 0,000 6,481E-03 0,02509383 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 6,481E-03 0,02505412 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,481E-03 0,02501454 ! membrane to membrane docking GO:0022614 14 7 0,000 6,481E-03 0,02497509 ! transcription termination GO:0006353 14 7 0,000 6,481E-03 0,02493576 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,481E-03 0,02489655 ! anaphase GO:0051322 18 7 0,000 6,481E-03 0,02485746 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 6,481E-03 0,0248185 ! axonal fasciculation GO:0007413 19 7 0,000 6,481E-03 0,02477966 ! negative regulation of nuclear division GO:0051784 15 7 0,000 6,481E-03 0,02474095 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 6,481E-03 0,02470235 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 6,481E-03 0,02466387 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 6,481E-03 0,02462551 ! diuresis GO:0030146 12 7 0,000 6,481E-03 0,02458727 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,481E-03 0,02454915 ! thiamin metabolic process GO:0006772 7 7 0,000 6,481E-03 0,02451115 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,481E-03 0,02447327 ! antibiotic transport GO:0042891 9 7 0,000 6,481E-03 0,0244355 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,481E-03 0,02439785 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 6,481E-03 0,02436032 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 6,481E-03 0,0243229 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 6,481E-03 0,02428559 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 6,481E-03 0,0242484 ! melanin biosynthetic process GO:0042438 10 7 0,000 6,481E-03 0,02421132 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 6,481E-03 0,02417436 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,481E-03 0,02413751 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,481E-03 0,02410077 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 6,481E-03 0,02406414 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 6,481E-03 0,02402762 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 6,481E-03 0,02399122 ! endosome to lysosome transport GO:0008333 12 7 0,000 6,481E-03 0,02395492 ! protein modification by small protein removal GO:0070646 19 7 0,000 6,481E-03 0,02391874 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 6,481E-03 0,02388266 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 6,481E-03 0,02384669 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 6,481E-03 0,02381083 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 6,481E-03 0,02377508 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,481E-03 0,02373944 ! muscle adaptation GO:0043500 13 7 0,000 6,481E-03 0,0237039 ! embryonic heart tube development GO:0035050 14 7 0,000 6,481E-03 0,02366847 ! retina homeostasis GO:0001895 12 7 0,000 6,481E-03 0,02363314 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 6,481E-03 0,02359792 ! protein amino acid prenylation GO:0018346 19 7 0,000 6,481E-03 0,0235628 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 6,481E-03 0,02352779 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 6,481E-03 0,02349289 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 7,404E-03 0,02679718 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 7,404E-03 0,02675754 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 7,404E-03 0,02671801 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 7,404E-03 0,02667861 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 7,404E-03 0,02663931 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,404E-03 0,02660014 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,404E-03 0,02656108 ! male meiosis GO:0007140 9 8 0,000 7,404E-03 0,02652213 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 7,404E-03 0,0264833 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 7,404E-03 0,02644458 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 7,404E-03 0,02640598 ! meiotic prophase I GO:0007128 14 8 0,000 7,404E-03 0,02636748 ! response to zinc ion GO:0010043 12 8 0,000 7,404E-03 0,0263291 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 7,404E-03 0,02629083 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,404E-03 0,02625268 ! oligopeptide transport GO:0006857 16 8 0,000 7,404E-03 0,02621463 ! actin-myosin filament sliding GO:0033275 13 8 0,000 7,404E-03 0,02617669 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 7,404E-03 0,02613886 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 7,404E-03 0,02610115 ! signal peptide processing GO:0006465 12 8 0,000 7,404E-03 0,02606354 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 7,404E-03 0,02602604 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 7,404E-03 0,02598864 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,404E-03 0,02595135 ! succinate metabolic process GO:0006105 17 8 0,000 7,404E-03 0,02591418 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 7,404E-03 0,0258771 ! membrane hyperpolarization GO:0060081 11 8 0,000 7,404E-03 0,02584013 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,404E-03 0,02580327 ! estrogen metabolic process GO:0008210 17 8 0,000 7,404E-03 0,02576652 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 7,404E-03 0,02572986 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,404E-03 0,02569332 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 7,404E-03 0,02565687 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,404E-03 0,02562053 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,404E-03 0,02558429 ! reflex GO:0060004 17 8 0,000 7,404E-03 0,02554816 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,404E-03 0,02551212 ! glycerolipid catabolic process GO:0046503 14 8 0,000 7,404E-03 0,02547619 ! hemoglobin metabolic process GO:0020027 14 8 0,000 7,404E-03 0,02544036 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,404E-03 0,02540463 ! pigment granule organization GO:0048753 17 8 0,000 7,404E-03 0,025369 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,404E-03 0,02533347 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 7,404E-03 0,02529803 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 7,404E-03 0,0252627 ! astrocyte differentiation GO:0048708 19 8 0,000 7,404E-03 0,02522747 ! histidine catabolic process GO:0006548 10 8 0,000 7,404E-03 0,02519233 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,404E-03 0,02515729 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 7,404E-03 0,02512235 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 7,404E-03 0,02508751 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 7,404E-03 0,02505276 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 7,404E-03 0,02501811 ! regulation of pigmentation during development GO:0048070 25 8 0,000 7,404E-03 0,02498356 ! melanin metabolic process GO:0006582 17 8 0,000 7,404E-03 0,0249491 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 7,404E-03 0,02491473 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 7,404E-03 0,02488046 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 7,404E-03 0,02484628 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,404E-03 0,0248122 ! macrophage activation GO:0042116 13 8 0,000 7,404E-03 0,02477821 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,404E-03 0,02474432 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,404E-03 0,02471051 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 7,404E-03 0,0246768 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,404E-03 0,02464318 ! purine salvage GO:0043101 12 8 0,000 7,404E-03 0,02460965 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 7,404E-03 0,02457622 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,404E-03 0,02454287 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 7,404E-03 0,02450961 ! osteoblast development GO:0002076 17 8 0,000 7,404E-03 0,02447645 ! positive regulation of vasodilation GO:0045909 14 8 0,000 7,404E-03 0,02444337 ! negative regulation of translational initiation GO:0045947 12 8 0,000 7,404E-03 0,02441038 ! Schwann cell differentiation GO:0014037 21 8 0,000 7,404E-03 0,02437749 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 7,404E-03 0,02434468 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,404E-03 0,02431195 ! response to UV-B GO:0010224 17 8 0,000 7,404E-03 0,02427932 ! protein targeting to vacuole GO:0006623 14 8 0,000 7,404E-03 0,02424678 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,404E-03 0,02421432 ! intermediate filament organization GO:0045109 12 8 0,000 7,404E-03 0,02418194 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 7,404E-03 0,02414966 ! cellular extravasation GO:0045123 13 8 0,000 7,404E-03 0,02411746 ! cardiac muscle cell development GO:0055013 14 8 0,000 7,404E-03 0,02408535 ! response to antibiotic GO:0046677 11 8 0,000 7,404E-03 0,02405332 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 7,404E-03 0,02402137 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 7,404E-03 0,02398952 ! DNA topological change GO:0006265 12 8 0,000 7,404E-03 0,02395774 ! response to tropane GO:0014073 15 8 0,000 7,404E-03 0,02392605 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 7,404E-03 0,02389444 ! melanosome transport GO:0032402 13 8 0,000 7,404E-03 0,02386292 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 7,404E-03 0,02383148 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 7,404E-03 0,02380012 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,404E-03 0,02376885 ! mast cell activation GO:0045576 14 8 0,000 7,404E-03 0,02373766 ! multicellular organismal aging GO:0010259 20 8 0,000 7,404E-03 0,02370655 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 7,404E-03 0,02367552 ! gas homeostasis GO:0033483 14 8 0,000 7,404E-03 0,02364457 ! dendrite morphogenesis GO:0048813 14 8 0,000 7,404E-03 0,0236137 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 7,404E-03 0,02358291 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 7,404E-03 0,02355221 ! nucleosome disassembly GO:0006337 14 8 0,000 7,404E-03 0,02352158 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,404E-03 0,02349103 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 7,404E-03 0,02346056 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,404E-03 0,02343017 ! establishment of chromosome localization GO:0051303 14 8 0,000 7,404E-03 0,02339986 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 7,404E-03 0,02336963 ! intracellular lipid transport GO:0032365 16 8 0,000 7,404E-03 0,02333948 ! response to tumor cell GO:0002347 16 8 0,000 7,404E-03 0,0233094 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,404E-03 0,0232794 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 7,404E-03 0,02324948 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 7,404E-03 0,02321963 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 7,404E-03 0,02318986 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,404E-03 0,02316017 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 7,404E-03 0,02313056 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 7,404E-03 0,02310101 ! hormone catabolic process GO:0042447 17 8 0,000 7,404E-03 0,02307155 ! glycolipid catabolic process GO:0019377 16 8 0,000 7,404E-03 0,02304216 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 7,404E-03 0,02301284 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 7,404E-03 0,0229836 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 7,404E-03 0,02295443 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,404E-03 0,02292534 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 7,404E-03 0,02289632 ! adult feeding behavior GO:0008343 10 8 0,000 7,404E-03 0,02286738 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 7,404E-03 0,0228385 ! ATP catabolic process GO:0006200 11 8 0,000 7,404E-03 0,0228097 ! blastocyst growth GO:0001832 19 8 0,000 7,404E-03 0,02278098 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,404E-03 0,02275232 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,404E-03 0,02272374 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 7,404E-03 0,02269523 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,404E-03 0,02266678 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 7,404E-03 0,02263842 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 7,404E-03 0,02261012 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 7,404E-03 0,02258189 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 7,404E-03 0,02255373 ! amino sugar catabolic process GO:0046348 11 8 0,000 7,404E-03 0,02252565 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 7,404E-03 0,02249763 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,404E-03 0,02246968 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 7,404E-03 0,0224418 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 7,404E-03 0,022414 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,404E-03 0,02238626 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 7,404E-03 0,02235858 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 7,404E-03 0,02233098 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,404E-03 0,02230345 ! NAD biosynthetic process GO:0009435 17 8 0,000 7,404E-03 0,02227598 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 7,404E-03 0,02224858 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 7,404E-03 0,02222125 ! axon extension GO:0048675 16 9 0,000 8,326E-03 0,024957 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,326E-03 0,02492641 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 8,326E-03 0,0248959 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 8,326E-03 0,02486547 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,326E-03 0,02483511 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 8,326E-03 0,02480482 ! cell proliferation in forebrain GO:0021846 18 9 0,000 8,326E-03 0,02477461 ! neutral lipid catabolic process GO:0046461 14 9 0,000 8,326E-03 0,02474447 ! reproductive behavior GO:0019098 22 9 0,000 8,326E-03 0,0247144 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,326E-03 0,02468441 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 8,326E-03 0,02465449 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 8,326E-03 0,02462464 ! UTP metabolic process GO:0046051 10 9 0,000 8,326E-03 0,02459487 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 8,326E-03 0,02456516 ! induction of positive chemotaxis GO:0050930 17 9 0,000 8,326E-03 0,02453553 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 8,326E-03 0,02450597 ! artery development GO:0060840 25 9 0,000 8,326E-03 0,02447648 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 8,326E-03 0,02444706 ! regulation of glycolysis GO:0006110 20 9 0,000 8,326E-03 0,02441771 ! cerebral cortex cell migration GO:0021795 18 9 0,000 8,326E-03 0,02438843 ! equilibrioception GO:0050957 20 9 0,000 8,326E-03 0,02435923 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 8,326E-03 0,02433009 ! chemosensory behavior GO:0007635 21 9 0,000 8,326E-03 0,02430102 ! microtubule bundle formation GO:0001578 22 9 0,000 8,326E-03 0,02427202 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,326E-03 0,02424309 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 8,326E-03 0,02421423 ! leukocyte degranulation GO:0043299 16 9 0,000 8,326E-03 0,02418544 ! ganglioside metabolic process GO:0001573 22 9 0,000 8,326E-03 0,02415672 ! negative regulation of endocytosis GO:0045806 12 9 0,000 8,326E-03 0,02412806 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 8,326E-03 0,02409947 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 8,326E-03 0,02407095 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,326E-03 0,0240425 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,326E-03 0,02401411 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 8,326E-03 0,0239858 ! protein targeting to ER GO:0045047 25 9 0,000 8,326E-03 0,02395754 ! ceramide biosynthetic process GO:0046513 20 9 0,000 8,326E-03 0,02392936 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 8,326E-03 0,02390124 ! T cell selection GO:0045058 27 9 0,000 8,326E-03 0,02387319 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 8,326E-03 0,0238452 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 8,326E-03 0,02381728 ! glycine catabolic process GO:0006546 15 9 0,000 8,326E-03 0,02378942 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 8,326E-03 0,02376163 ! endosome organization GO:0007032 20 9 0,000 8,326E-03 0,0237339 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 8,326E-03 0,02370624 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 8,326E-03 0,02367864 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,326E-03 0,02365111 ! mannose metabolic process GO:0006013 13 9 0,000 8,326E-03 0,02362364 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 8,326E-03 0,02359623 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 8,326E-03 0,02356889 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 8,326E-03 0,02354161 ! Rac protein signal transduction GO:0016601 20 9 0,000 8,326E-03 0,0235144 ! receptor clustering GO:0043113 20 9 0,000 8,326E-03 0,02348725 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 8,326E-03 0,02346015 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,326E-03 0,02343313 ! retinol metabolic process GO:0042572 20 9 0,000 8,326E-03 0,02340616 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 8,326E-03 0,02337926 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 8,326E-03 0,02335242 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 8,326E-03 0,02332564 ! macrophage differentiation GO:0030225 15 9 0,000 8,326E-03 0,02329892 ! oligodendrocyte development GO:0014003 11 9 0,000 8,326E-03 0,02327226 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 8,326E-03 0,02324566 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,326E-03 0,02321913 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 8,326E-03 0,02319265 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,326E-03 0,02316623 ! response to amine stimulus GO:0014075 13 9 0,000 8,326E-03 0,02313988 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,326E-03 0,02311358 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 8,326E-03 0,02308735 ! erythrocyte development GO:0048821 17 9 0,000 8,326E-03 0,02306117 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,326E-03 0,02303506 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 8,326E-03 0,023009 ! renal water homeostasis GO:0003091 15 9 0,000 8,326E-03 0,022983 ! postreplication repair GO:0006301 25 9 0,000 8,326E-03 0,02295706 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 8,326E-03 0,02293118 ! icosanoid secretion GO:0032309 15 9 0,000 8,326E-03 0,02290535 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,326E-03 0,02287959 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 8,326E-03 0,02285388 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 8,326E-03 0,02282823 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 8,326E-03 0,02280264 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,326E-03 0,0227771 ! sterol catabolic process GO:0016127 14 9 0,000 8,326E-03 0,02275163 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,326E-03 0,02272621 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 8,326E-03 0,02270084 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 8,326E-03 0,02267553 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 8,326E-03 0,02265028 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 8,326E-03 0,02262509 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 8,326E-03 0,02259995 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 8,326E-03 0,02257487 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 8,326E-03 0,02254984 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 8,326E-03 0,02252487 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 8,326E-03 0,02249995 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,326E-03 0,02247509 ! purine base metabolic process GO:0006144 25 9 0,000 8,326E-03 0,02245028 ! pigment granule transport GO:0051904 17 9 0,000 8,326E-03 0,02242553 ! regulation of telomere maintenance GO:0032204 17 9 0,000 8,326E-03 0,02240083 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 8,326E-03 0,02237619 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 8,326E-03 0,0223516 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,326E-03 0,02232706 ! regulation of amino acid transport GO:0051955 12 9 0,000 8,326E-03 0,02230258 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 8,326E-03 0,02227815 ! mitochondrion localization GO:0051646 18 9 0,000 8,326E-03 0,02225378 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 9,247E-03 0,02468829 ! regulation of developmental growth GO:0048638 16 10 0,000 9,247E-03 0,02466134 ! autophagic vacuole formation GO:0000045 17 10 0,000 9,247E-03 0,02463445 ! negative regulation of blood pressure GO:0045776 26 10 0,000 9,247E-03 0,02460761 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 9,247E-03 0,02458083 ! associative learning GO:0008306 21 10 0,000 9,247E-03 0,02455412 ! regulation of phosphatase activity GO:0010921 28 10 0,000 9,247E-03 0,02452746 ! cell volume homeostasis GO:0006884 17 10 0,000 9,247E-03 0,02450085 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 9,247E-03 0,02447431 ! CTP metabolic process GO:0046036 11 10 0,000 9,247E-03 0,02444782 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 9,247E-03 0,02442139 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 9,247E-03 0,02439502 ! GTP metabolic process GO:0046039 11 10 0,000 9,247E-03 0,0243687 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 9,247E-03 0,02434244 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 9,247E-03 0,02431624 ! social behavior GO:0035176 29 10 0,000 9,247E-03 0,02429009 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 9,247E-03 0,024264 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 9,247E-03 0,02423797 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 9,247E-03 0,02421199 ! androgen metabolic process GO:0008209 17 10 0,000 9,247E-03 0,02418607 ! phospholipid efflux GO:0033700 19 10 0,000 9,247E-03 0,0241602 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 9,247E-03 0,02413439 ! bile acid and bile salt transport GO:0015721 15 10 0,000 9,247E-03 0,02410863 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 9,247E-03 0,02408293 ! positive regulation of heart contraction GO:0045823 17 10 0,000 9,247E-03 0,02405728 ! lung alveolus development GO:0048286 26 10 0,000 9,247E-03 0,02403169 ! pathogenesis GO:0009405 17 10 0,000 9,247E-03 0,02400615 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 9,247E-03 0,02398066 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 9,247E-03 0,02395523 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 9,247E-03 0,02392986 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 9,247E-03 0,02390454 ! endoderm development GO:0007492 18 10 0,000 9,247E-03 0,02387927 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 9,247E-03 0,02385405 ! arginine catabolic process GO:0006527 17 10 0,000 9,247E-03 0,02382889 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 9,247E-03 0,02380378 ! proline metabolic process GO:0006560 13 10 0,000 9,247E-03 0,02377872 ! glucan biosynthetic process GO:0009250 14 10 0,000 9,247E-03 0,02375372 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 9,247E-03 0,02372877 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 9,247E-03 0,02370387 ! V(D)J recombination GO:0033151 34 10 0,000 9,247E-03 0,02367902 ! reverse cholesterol transport GO:0043691 19 10 0,000 9,247E-03 0,02365423 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 9,247E-03 0,02362948 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 9,247E-03 0,02360479 ! B cell proliferation GO:0042100 19 10 0,000 9,247E-03 0,02358015 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 9,247E-03 0,02355556 ! regulation of sodium ion transport GO:0002028 26 10 0,000 9,247E-03 0,02353103 ! multicellular organism growth GO:0035264 19 10 0,000 9,247E-03 0,02350654 ! phagocytosis, engulfment GO:0006911 33 10 0,000 9,247E-03 0,02348211 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 9,247E-03 0,02345772 ! ruffle organization GO:0031529 17 10 0,000 9,247E-03 0,02343339 ! epithelial cell development GO:0002064 21 10 0,000 9,247E-03 0,0234091 ! lens development in camera-type eye GO:0002088 17 10 0,000 9,247E-03 0,02338487 ! retinoic acid metabolic process GO:0042573 14 10 0,000 9,247E-03 0,02336069 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 9,247E-03 0,02333656 ! positive regulation of translational initiation GO:0045948 12 10 0,000 9,247E-03 0,02331247 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 9,247E-03 0,02328844 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 9,247E-03 0,02326446 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 9,247E-03 0,02324052 ! motor axon guidance GO:0008045 22 10 0,000 9,247E-03 0,02321664 ! copper ion homeostasis GO:0055070 13 10 0,000 9,247E-03 0,0231928 ! regulation of bone resorption GO:0045124 25 10 0,000 9,247E-03 0,02316901 ! protein heterooligomerization GO:0051291 17 10 0,000 9,247E-03 0,02314527 ! regulation of gliogenesis GO:0014013 23 10 0,000 9,247E-03 0,02312158 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 9,247E-03 0,02309794 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 9,247E-03 0,02307435 ! segment specification GO:0007379 15 10 0,000 9,247E-03 0,0230508 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 9,247E-03 0,02302731 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 9,247E-03 0,02300386 ! blastoderm segmentation GO:0007350 19 10 0,000 9,247E-03 0,02298045 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 9,247E-03 0,0229571 ! response to dsRNA GO:0043331 23 10 0,000 9,247E-03 0,02293379 ! DNA ligation GO:0006266 18 10 0,000 9,247E-03 0,02291053 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 9,247E-03 0,02288732 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 9,247E-03 0,02286416 ! melanosome localization GO:0032400 16 10 0,000 9,247E-03 0,02284104 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 9,247E-03 0,02281797 ! regulation of B cell differentiation GO:0045577 24 10 0,000 9,247E-03 0,02279494 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 9,247E-03 0,02277196 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 9,247E-03 0,02274903 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 9,247E-03 0,02272614 ! induction of an organ GO:0001759 17 10 0,000 9,247E-03 0,0227033 ! leukocyte activation during immune response GO:0002366 15 10 0,000 9,247E-03 0,02268051 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 9,247E-03 0,02265776 ! protein sumoylation GO:0016925 17 10 0,000 9,247E-03 0,02263506 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 9,247E-03 0,0226124 ! hindbrain morphogenesis GO:0021575 19 10 0,000 9,247E-03 0,02258979 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 9,247E-03 0,02256722 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 9,247E-03 0,0225447 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 9,247E-03 0,02252222 ! salivary gland development GO:0007431 28 10 0,000 9,247E-03 0,02249979 ! ubiquinone metabolic process GO:0006743 17 10 0,000 9,247E-03 0,0224774 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 9,247E-03 0,02245506 ! midbrain development GO:0030901 14 10 0,000 9,247E-03 0,02243276 ! musculoskeletal movement GO:0050881 16 10 0,000 9,247E-03 0,0224105 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 9,247E-03 0,02238829 ! methionine biosynthetic process GO:0009086 21 10 0,000 9,247E-03 0,02236613 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 9,247E-03 0,022344 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 9,247E-03 0,02232192 ! quaternary ammonium group transport GO:0015697 22 10 0,000 9,247E-03 0,02229989 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 9,247E-03 0,0222779 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 9,247E-03 0,02225595 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 9,247E-03 0,02223404 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 9,247E-03 0,02221218 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 9,247E-03 0,02219036 ! establishment of pigment granule localization GO:0051905 18 10 0,000 9,247E-03 0,02216858 ! blastocyst formation GO:0001825 18 10 0,000 9,247E-03 0,02214685 ! regulation of fibrinolysis GO:0051917 20 10 0,000 9,247E-03 0,02212516 ! cerebellar cortex development GO:0021695 16 10 0,000 9,247E-03 0,02210351 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 9,247E-03 0,0220819 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 9,247E-03 0,02206034 ! response to nicotine GO:0035094 20 10 0,000 9,247E-03 0,02203882 ! negative regulation of immune effector process GO:0002698 23 10 0,000 9,247E-03 0,02201734 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 9,247E-03 0,0219959 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01016684 0,02416108 ! respiratory burst GO:0045730 17 11 0,000 0,01016684 0,0241376 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01016684 0,02411417 ! neuron fate specification GO:0048665 18 11 0,000 0,01016684 0,02409078 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01016684 0,02406743 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01016684 0,02404414 ! thyroid gland development GO:0030878 26 11 0,000 0,01016684 0,02402088 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01016684 0,02399767 ! synapsis GO:0007129 14 11 0,000 0,01016684 0,02397451 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01016684 0,02395139 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01016684 0,02392832 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01016684 0,02390529 ! response to pain GO:0048265 27 11 0,000 0,01016684 0,0238823 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01016684 0,02385936 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01016684 0,02383646 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01016684 0,02381361 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01016684 0,0237908 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01016684 0,02376803 ! bone resorption GO:0045453 16 11 0,000 0,01016684 0,02374531 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01016684 0,02372263 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01016684 0,02369999 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01016684 0,0236774 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01016684 0,02365485 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01016684 0,02363234 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01016684 0,02360988 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01016684 0,02358746 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01016684 0,02356508 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01016684 0,02354274 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01016684 0,02352045 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01016684 0,0234982 ! UV protection GO:0009650 20 11 0,000 0,01016684 0,02347599 ! adult heart development GO:0007512 16 11 0,000 0,01016684 0,02345382 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01016684 0,02343169 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01016684 0,02340961 ! macroautophagy GO:0016236 19 11 0,000 0,01016684 0,02338756 ! temperature homeostasis GO:0001659 18 11 0,000 0,01016684 0,02336556 ! behavioral fear response GO:0001662 27 11 0,000 0,01016684 0,0233436 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01016684 0,02332168 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01016684 0,02329981 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01016684 0,02327797 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01016684 0,02325617 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01016684 0,02323442 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01016684 0,0232127 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01016684 0,02319103 ! regulation of organ growth GO:0046620 14 11 0,000 0,01016684 0,0231694 ! pigment granule localization GO:0051875 20 11 0,000 0,01016684 0,0231478 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01016684 0,02312625 ! vasoconstriction GO:0042310 20 11 0,000 0,01016684 0,02310474 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01016684 0,02308326 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01016684 0,02306183 ! embryonic axis specification GO:0000578 19 11 0,000 0,01016684 0,02304044 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01016684 0,02301908 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01016684 0,02299777 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01016684 0,0229765 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01016684 0,02295526 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01016684 0,02293406 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01016684 0,02291291 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01016684 0,02289179 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01016684 0,02287071 ! prophase GO:0051324 17 11 0,000 0,01016684 0,02284967 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01016684 0,02282867 ! nucleosome positioning GO:0016584 15 11 0,000 0,01016684 0,02280771 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01016684 0,02278678 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01016684 0,0227659 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01016684 0,02274505 ! apical protein localization GO:0045176 18 11 0,000 0,01016684 0,02272424 ! acid secretion GO:0046717 20 11 0,000 0,01016684 0,02270347 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01016684 0,02268273 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01016684 0,02266204 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01016684 0,02264138 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01016684 0,02262076 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01016684 0,02260017 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01016684 0,02257963 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01016684 0,02255912 ! cholesterol efflux GO:0033344 21 11 0,000 0,01016684 0,02253865 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01016684 0,02251822 ! oocyte development GO:0048599 20 11 0,000 0,01016684 0,02249782 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01016684 0,02247746 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01016684 0,02245714 ! embryonic gut development GO:0048566 19 11 0,000 0,01016684 0,02243685 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01016684 0,0224166 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01016684 0,02239639 ! activation of innate immune response GO:0002218 16 11 0,000 0,01016684 0,02237621 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01016684 0,02235607 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01016684 0,02233596 ! lysogeny GO:0030069 22 11 0,000 0,01016684 0,0223159 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01016684 0,02229586 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01016684 0,02227587 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01016684 0,02225591 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01016684 0,02223598 ! nucleus localization GO:0051647 22 11 0,000 0,01016684 0,02221609 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01108611 0,02420319 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01108611 0,02418158 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01108611 0,02416001 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01108611 0,02413848 ! virus-host interaction GO:0019048 30 12 0,000 0,01108611 0,02411698 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01108611 0,02409553 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01108611 0,02407411 ! protein complex disassembly GO:0043241 28 12 0,000 0,01108611 0,02405273 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01108611 0,02403139 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01108611 0,02401008 ! hippocampus development GO:0021766 29 12 0,000 0,01108611 0,02398882 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01108611 0,02396759 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01108611 0,0239464 ! T cell proliferation GO:0042098 32 12 0,000 0,01108611 0,02392524 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01108611 0,02390413 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01108611 0,02388305 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01108611 0,023862 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01108611 0,023841 ! drug transport GO:0015893 16 12 0,000 0,01108611 0,02382003 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01108611 0,0237991 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01108611 0,0237782 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01108611 0,02375735 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01108611 0,02373652 ! focal adhesion formation GO:0048041 37 12 0,000 0,01108611 0,02371574 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01108611 0,02369499 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01108611 0,02367428 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01108611 0,0236536 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01108611 0,02363296 ! lipid digestion GO:0044241 21 12 0,000 0,01108611 0,02361236 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01108611 0,02359179 ! entry into host cell GO:0030260 34 12 0,000 0,01108611 0,02357126 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01108611 0,02355076 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01108611 0,0235303 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01108611 0,02350987 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01108611 0,02348948 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01108611 0,02346913 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01108611 0,02344881 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01108611 0,02342852 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01108611 0,02340827 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01108611 0,02338806 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01108611 0,02336788 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01108611 0,02334774 ! cranial nerve development GO:0021545 23 12 0,000 0,01108611 0,02332763 ! fucose catabolic process GO:0019317 25 12 0,000 0,01108611 0,02330755 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01108611 0,02328751 ! histone acetylation GO:0016573 27 12 0,000 0,01108611 0,0232675 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01108611 0,02324753 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01108611 0,02322759 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01108611 0,02320769 ! zymogen activation GO:0031638 18 12 0,000 0,01108611 0,02318782 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01108611 0,02316798 ! T cell homeostasis GO:0043029 28 12 0,000 0,01108611 0,02314818 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01108611 0,02312841 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01108611 0,02310868 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01108611 0,02308898 ! oocyte differentiation GO:0009994 21 12 0,000 0,01108611 0,02306931 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01108611 0,02304968 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01108611 0,02303008 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01108611 0,02301051 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01108611 0,02299098 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01108611 0,02297148 ! defense response to fungus GO:0050832 15 12 0,000 0,01108611 0,02295201 ! developmental induction GO:0031128 22 12 0,000 0,01108611 0,02293258 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01108611 0,02291318 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01108611 0,02289381 ! response to cold GO:0009409 17 12 0,000 0,01108611 0,02287447 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01108611 0,02285517 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01108611 0,0228359 ! localization within membrane GO:0051668 26 12 0,000 0,01108611 0,02281666 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01200456 0,02468614 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01200456 0,02466538 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01200456 0,02464465 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01200456 0,02462396 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01200456 0,0246033 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01200456 0,02458268 ! peroxisomal transport GO:0043574 28 13 0,000 0,01200456 0,02456209 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01200456 0,02454153 ! cartilage condensation GO:0001502 22 13 0,000 0,01200456 0,02452101 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01200456 0,02450053 ! organelle fusion GO:0048284 36 13 0,000 0,01200456 0,02448008 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01200456 0,02445966 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01200456 0,02443928 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01200456 0,02441893 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01200456 0,02439861 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01200456 0,02437833 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01200456 0,02435808 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01200456 0,02433787 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01200456 0,02431769 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01200456 0,02429754 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01200456 0,02427743 ! methionine metabolic process GO:0006555 31 13 0,000 0,01200456 0,02425735 ! plasma membrane organization GO:0007009 27 13 0,000 0,01200456 0,0242373 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01200456 0,02421729 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01200456 0,0241973 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01200456 0,02417736 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01200456 0,02415744 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01200456 0,02413756 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01200456 0,02411771 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01200456 0,02409789 ! exocrine system development GO:0035272 34 13 0,000 0,01200456 0,02407811 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01200456 0,02405835 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01200456 0,02403863 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01200456 0,02401895 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01200456 0,02399929 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01200456 0,02397967 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01200456 0,02396008 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01200456 0,02394052 ! protein homotetramerization GO:0051289 24 13 0,000 0,01200456 0,02392099 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01200456 0,02390149 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01200456 0,02388203 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01200456 0,0238626 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01200456 0,0238432 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01200456 0,02382383 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01200456 0,02380449 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01200456 0,02378518 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01200456 0,02376591 ! histone methylation GO:0016571 29 13 0,000 0,01200456 0,02374667 ! chromatin silencing GO:0006342 29 13 0,000 0,01200456 0,02372745 ! gland morphogenesis GO:0022612 31 13 0,000 0,01200456 0,02370827 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01200456 0,02368912 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01200456 0,02367 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01200456 0,02365091 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01200456 0,02363186 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01200456 0,02361283 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01200456 0,02359383 ! spleen development GO:0048536 24 13 0,000 0,01200456 0,02357487 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01200456 0,02355593 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01200456 0,02353702 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01200456 0,02351815 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01200456 0,02349931 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01200456 0,02348049 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01200456 0,02346171 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01200456 0,02344295 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01200456 0,02342423 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01200456 0,02340553 ! insulin secretion GO:0030073 24 13 0,000 0,01200456 0,02338687 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01200456 0,02336823 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01200456 0,02334963 ! acrosome reaction GO:0007340 19 13 0,000 0,01200456 0,02333105 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01200456 0,02331251 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01200456 0,02329399 ! rRNA transcription GO:0009303 28 14 0,000 0,01292217 0,02505466 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01292217 0,02503479 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01292217 0,02501495 ! water transport GO:0006833 21 14 0,000 0,01292217 0,02499515 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01292217 0,02497537 ! non-recombinational repair GO:0000726 29 14 0,000 0,01292217 0,02495563 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01292217 0,02493592 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01292217 0,02491624 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01292217 0,02489659 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01292217 0,02487697 ! lipid localization GO:0010876 32 14 0,000 0,01292217 0,02485738 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01292217 0,02483782 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01292217 0,0248183 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01292217 0,0247988 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01292217 0,02477933 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01292217 0,0247599 ! arginine metabolic process GO:0006525 21 14 0,000 0,01292217 0,02474049 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01292217 0,02472112 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01292217 0,02470178 ! regulation of heart rate GO:0002027 25 14 0,000 0,01292217 0,02468246 ! fear response GO:0042596 34 14 0,000 0,01292217 0,02466318 ! organic alcohol transport GO:0015850 29 14 0,000 0,01292217 0,02464393 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01292217 0,0246247 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01292217 0,02460551 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01292217 0,02458635 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01292217 0,02456722 ! bone mineralization GO:0030282 18 14 0,000 0,01292217 0,02454811 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01292217 0,02452904 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01292217 0,02450999 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01292217 0,02449098 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01292217 0,02447199 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01292217 0,02445304 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01292217 0,02443411 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01292217 0,02441521 ! ribosome assembly GO:0042255 18 14 0,000 0,01292217 0,02439635 ! cerebellum development GO:0021549 23 14 0,000 0,01292217 0,02437751 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01292217 0,0243587 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01292217 0,02433992 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01292217 0,02432116 ! response to gamma radiation GO:0010332 30 14 0,000 0,01292217 0,02430244 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01292217 0,02428375 ! NADP metabolic process GO:0006739 24 14 0,000 0,01292217 0,02426508 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01292217 0,02424644 ! oxygen transport GO:0015671 22 14 0,000 0,01292217 0,02422784 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01292217 0,02420926 ! male genitalia development GO:0030539 26 14 0,000 0,01292217 0,02419071 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01292217 0,02417218 ! regulation of axon extension GO:0030516 43 14 0,000 0,01292217 0,02415369 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01292217 0,02413522 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01292217 0,02411678 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01292217 0,02409838 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01383896 0,0257884 ! lactation GO:0007595 30 15 0,000 0,01383896 0,02576874 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01383896 0,02574912 ! reproductive cellular process GO:0048610 22 15 0,000 0,01383896 0,02572952 ! tRNA modification GO:0006400 24 15 0,000 0,01383896 0,02570995 ! superoxide anion generation GO:0042554 22 15 0,000 0,01383896 0,02569042 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01383896 0,02567091 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01383896 0,02565143 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01383896 0,02563199 ! copper ion transport GO:0006825 22 15 0,000 0,01383896 0,02561257 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01383896 0,02559318 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01383896 0,02557382 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01383896 0,02555449 ! sulfate transport GO:0008272 27 15 0,000 0,01383896 0,02553519 ! response to cAMP GO:0051591 25 15 0,000 0,01383896 0,02551592 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01383896 0,02549667 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01383896 0,02547746 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01383896 0,02545828 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01383896 0,02543912 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01383896 0,02541999 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01383896 0,02540089 ! vesicle coating GO:0006901 38 15 0,000 0,01383896 0,02538182 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01383896 0,02536278 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01383896 0,02534377 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01383896 0,02532479 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01383896 0,02530583 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01383896 0,0252869 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01383896 0,025268 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01383896 0,02524913 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01383896 0,02523029 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01383896 0,02521148 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01383896 0,02519269 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01383896 0,02517393 ! histone deacetylation GO:0016575 24 15 0,000 0,01383896 0,0251552 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01383896 0,0251365 ! water homeostasis GO:0030104 28 15 0,000 0,01383896 0,02511782 ! cofactor transport GO:0051181 30 15 0,000 0,01383896 0,02509918 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01383896 0,02508056 ! muscle maintenance GO:0046716 26 15 0,000 0,01383896 0,02506196 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01383896 0,0250434 ! intestinal absorption GO:0050892 31 15 0,000 0,01383896 0,02502486 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01383896 0,02500635 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01383896 0,02498787 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01383896 0,02496942 ! cell killing GO:0001906 32 15 0,000 0,01383896 0,02495099 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01383896 0,02493259 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01383896 0,02491422 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01383896 0,02489587 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01383896 0,02487755 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01383896 0,02485926 ! actin filament polymerization GO:0030041 27 15 0,000 0,01383896 0,02484099 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01383896 0,02482275 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01475493 0,02644629 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01475493 0,0264269 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01475493 0,02640754 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01475493 0,02638821 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01475493 0,0263689 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01475493 0,02634963 ! bone remodeling GO:0046849 28 16 0,000 0,01475493 0,02633038 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01475493 0,02631116 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01475493 0,02629197 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01475493 0,02627281 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01475493 0,02625367 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01475493 0,02623457 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01475493 0,02621549 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01475493 0,02619643 ! startle response GO:0001964 28 16 0,000 0,01475493 0,02617741 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01475493 0,02615841 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01475493 0,02613944 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01475493 0,0261205 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01475493 0,02610159 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01475493 0,0260827 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01475493 0,02606384 ! pituitary gland development GO:0021983 30 16 0,000 0,01475493 0,02604501 ! response to osmotic stress GO:0006970 27 16 0,000 0,01475493 0,0260262 ! lysosomal transport GO:0007041 31 16 0,000 0,01475493 0,02600743 ! fructose metabolic process GO:0006000 25 16 0,000 0,01475493 0,02598868 ! L-amino acid transport GO:0015807 33 16 0,000 0,01475493 0,02596995 ! stem cell development GO:0048864 46 16 0,000 0,01475493 0,02595125 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01475493 0,02593258 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01475493 0,02591394 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01475493 0,02589533 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01475493 0,02587674 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01475493 0,02585817 ! axon cargo transport GO:0008088 46 16 0,000 0,01475493 0,02583964 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01475493 0,02582113 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01475493 0,02580264 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01475493 0,02578419 ! DNA replication initiation GO:0006270 28 16 0,000 0,01475493 0,02576576 ! neuron recognition GO:0008038 40 16 0,000 0,01475493 0,02574735 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01475493 0,02572897 ! tissue regeneration GO:0042246 27 16 0,000 0,01475493 0,02571062 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01475493 0,0256923 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01475493 0,025674 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01475493 0,02565572 ! biomineral formation GO:0031214 22 16 0,000 0,01475493 0,02563748 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01475493 0,02561926 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01475493 0,02560106 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01475493 0,02558289 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01475493 0,02556475 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01475493 0,02554663 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01475493 0,02552854 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01475493 0,02551047 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01475493 0,02549243 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01475493 0,02547441 ! peptide hormone processing GO:0016486 27 16 0,000 0,01475493 0,02545642 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01567007 0,02701622 ! metencephalon development GO:0022037 32 17 0,000 0,01567007 0,02699716 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01567007 0,02697814 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01567007 0,02695914 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01567007 0,02694017 ! signal complex assembly GO:0007172 47 17 0,000 0,01567007 0,02692122 ! filopodium assembly GO:0046847 42 17 0,000 0,01567007 0,0269023 ! endothelial cell migration GO:0043542 31 17 0,000 0,01567007 0,02688341 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01567007 0,02686455 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01567007 0,02684571 ! glial cell development GO:0021782 28 17 0,000 0,01567007 0,0268269 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01567007 0,02680811 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01567007 0,02678935 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01567007 0,02677061 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01567007 0,02675191 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01567007 0,02673323 ! myoblast differentiation GO:0045445 50 17 0,000 0,01567007 0,02671457 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01567007 0,02669594 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01567007 0,02667734 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01567007 0,02665876 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01567007 0,02664021 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01567007 0,02662168 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01567007 0,02660318 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01567007 0,02658471 ! NAD metabolic process GO:0019674 33 17 0,000 0,01567007 0,02656626 ! membrane budding GO:0006900 42 17 0,000 0,01567007 0,02654784 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01567007 0,02652944 ! regulation of protein binding GO:0043393 33 17 0,000 0,01567007 0,02651107 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01567007 0,02649272 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01567007 0,0264744 ! genitalia development GO:0048806 32 17 0,000 0,01567007 0,0264561 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01567007 0,02643783 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01567007 0,02641959 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01567007 0,02640137 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01567007 0,02638317 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01567007 0,026365 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01567007 0,02634685 ! steroid catabolic process GO:0006706 34 17 0,000 0,01567007 0,02632873 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01567007 0,02631064 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01567007 0,02629257 ! gas transport GO:0015669 26 17 0,000 0,01567007 0,02627452 ! organic cation transport GO:0015695 32 17 0,000 0,01567007 0,0262565 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01567007 0,02623851 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01567007 0,02622053 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01567007 0,02620259 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01658438 0,02771248 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01658438 0,02769354 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01658438 0,02767463 ! limbic system development GO:0021761 40 18 0,000 0,01658438 0,02765574 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01658438 0,02763687 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01658438 0,02761803 ! adult walking behavior GO:0007628 36 18 0,000 0,01658438 0,02759922 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01658438 0,02758043 ! heart looping GO:0001947 34 18 0,000 0,01658438 0,02756167 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01658438 0,02754293 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01658438 0,02752422 ! centrosome cycle GO:0007098 26 18 0,000 0,01658438 0,02750553 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01658438 0,02748687 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01658438 0,02746824 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01658438 0,02744963 ! glycine metabolic process GO:0006544 30 18 0,000 0,01658438 0,02743104 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01658438 0,02741248 ! response to retinoic acid GO:0032526 31 18 0,000 0,01658438 0,02739395 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01658438 0,02737544 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01658438 0,02735696 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01658438 0,0273385 ! DNA integration GO:0015074 32 18 0,000 0,01658438 0,02732006 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01658438 0,02730165 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01658438 0,02728327 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01658438 0,02726491 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01658438 0,02724657 ! neural crest cell migration GO:0001755 41 18 0,000 0,01658438 0,02722826 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01658438 0,02720997 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01658438 0,02719171 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01658438 0,02717348 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01658438 0,02715526 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01658438 0,02713707 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01658438 0,02711891 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01658438 0,02710077 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01658438 0,02708266 ! detection of bacterium GO:0016045 22 18 0,000 0,01658438 0,02706456 ! nerve development GO:0021675 34 18 0,000 0,01658438 0,0270465 ! defense response to virus GO:0051607 43 18 0,000 0,01658438 0,02702845 ! microspike assembly GO:0030035 46 18 0,000 0,01658438 0,02701043 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01658438 0,02699244 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01749788 0,02846026 ! positive regulation of translation GO:0045727 31 19 0,000 0,01749788 0,02844133 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01749788 0,02842242 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01749788 0,02840353 ! neuron maturation GO:0042551 46 19 0,000 0,01749788 0,02838467 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01749788 0,02836583 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01749788 0,02834702 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01749788 0,02832824 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01749788 0,02830948 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01749788 0,02829074 ! inositol metabolic process GO:0006020 33 19 0,000 0,01749788 0,02827203 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01749788 0,02825335 ! memory GO:0007613 34 19 0,000 0,01749788 0,02823468 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01749788 0,02821605 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01749788 0,02819744 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01749788 0,02817885 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01749788 0,02816029 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01749788 0,02814175 ! cerebral cortex development GO:0021987 40 19 0,000 0,01749788 0,02812323 ! pigmentation during development GO:0048066 42 19 0,000 0,01749788 0,02810474 ! response to vitamin A GO:0033189 32 19 0,000 0,01749788 0,02808628 ! heme metabolic process GO:0042168 40 19 0,000 0,01749788 0,02806784 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01749788 0,02804942 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01749788 0,02803102 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01749788 0,02801266 ! response to fungus GO:0009620 26 19 0,000 0,01749788 0,02799431 ! peptide cross-linking GO:0018149 39 19 0,000 0,01749788 0,02797599 ! protein export from nucleus GO:0006611 40 19 0,000 0,01749788 0,02795769 ! heart process GO:0003015 32 19 0,000 0,01749788 0,02793942 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01749788 0,02792117 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01749788 0,02790295 ! visual learning GO:0008542 38 19 0,000 0,01749788 0,02788474 ! cellular pigmentation GO:0033059 37 19 0,000 0,01749788 0,02786657 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01749788 0,02784841 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01749788 0,02783028 ! vitamin transport GO:0051180 31 19 0,000 0,01749788 0,02781217 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01749788 0,02779409 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01749788 0,02777603 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01749788 0,027758 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01749788 0,02773998 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01749788 0,02772199 ! cilium assembly GO:0042384 38 19 0,000 0,01749788 0,02770403 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01749788 0,02768608 ! protein secretion GO:0009306 45 20 0,000 0,01841055 0,0291113 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01841055 0,02909247 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01841055 0,02907367 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01841055 0,02905489 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01841055 0,02903613 ! skin development GO:0043588 42 20 0,000 0,01841055 0,0290174 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01841055 0,02899869 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01841055 0,02898 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01841055 0,02896134 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01841055 0,02894271 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01841055 0,02892409 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01841055 0,0289055 ! response to vitamin GO:0033273 36 20 0,000 0,01841055 0,02888694 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01841055 0,0288684 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01841055 0,02884988 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01841055 0,02883139 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01841055 0,02881292 ! response to alkaloid GO:0043279 38 20 0,000 0,01841055 0,02879447 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01841055 0,02877605 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01841055 0,02875765 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01841055 0,02873927 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01841055 0,02872092 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01841055 0,02870259 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01841055 0,02868429 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01841055 0,02866601 ! body fluid secretion GO:0007589 33 20 0,000 0,01841055 0,02864775 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01841055 0,02862951 ! peptide secretion GO:0002790 38 20 0,000 0,01841055 0,0286113 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01841055 0,02859311 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01841055 0,02857495 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01841055 0,0285568 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01841055 0,02853868 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01841055 0,02852059 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01841055 0,02850251 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01841055 0,02848446 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01841055 0,02846643 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01841055 0,02844843 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01841055 0,02843044 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01841055 0,02841248 ! regulation of glucose import GO:0046324 30 20 0,000 0,01841055 0,02839455 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01841055 0,02837663 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01841055 0,02835874 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01841055 0,02834087 ! negative regulation of translation GO:0017148 32 20 0,000 0,01841055 0,02832302 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01841055 0,0283052 ! regulation of cell killing GO:0031341 46 21 0,000 0,01932239 0,02968843 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01932239 0,02966977 ! hormone secretion GO:0046879 39 21 0,000 0,01932239 0,02965113 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01932239 0,02963252 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01932239 0,02961393 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01932239 0,02959536 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01932239 0,02957682 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01932239 0,0295583 ! ovarian follicle development GO:0001541 39 21 0,000 0,01932239 0,0295398 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01932239 0,02952133 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01932239 0,02950288 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01932239 0,02948445 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01932239 0,02946605 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01932239 0,02944766 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01932239 0,02942931 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01932239 0,02941097 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01932239 0,02939266 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01932239 0,02937437 ! sensory perception of pain GO:0019233 33 21 0,000 0,01932239 0,0293561 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01932239 0,02933785 ! diencephalon development GO:0021536 36 21 0,000 0,01932239 0,02931963 ! collagen fibril organization GO:0030199 62 21 0,000 0,01932239 0,02930143 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01932239 0,02928325 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01932239 0,0292651 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01932239 0,02924697 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01932239 0,02922886 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01932239 0,02921077 ! collagen catabolic process GO:0030574 29 21 0,000 0,01932239 0,02919271 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01932239 0,02917466 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01932239 0,02915664 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01932239 0,02913865 ! actin filament-based movement GO:0030048 47 21 0,000 0,01932239 0,02912067 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01932239 0,02910272 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02023342 0,03045609 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02023342 0,03043734 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02023342 0,03041861 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02023342 0,0303999 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02023342 0,03038122 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02023342 0,03036256 ! microtubule-based transport GO:0010970 59 22 0,000 0,02023342 0,03034392 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02023342 0,0303253 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02023342 0,03030671 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02023342 0,03028814 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02023342 0,03026959 ! cellular response to starvation GO:0009267 37 22 0,000 0,02023342 0,03025107 ! vacuolar transport GO:0007034 41 22 0,000 0,02023342 0,03023256 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02023342 0,03021408 ! fucose metabolic process GO:0006004 44 22 0,000 0,02023342 0,03019563 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02023342 0,03017719 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02023342 0,03015878 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02023342 0,03014039 ! ureteric bud development GO:0001657 50 22 0,000 0,02023342 0,03012202 ! cell aging GO:0007569 48 22 0,000 0,02023342 0,03010368 ! stem cell differentiation GO:0048863 57 22 0,000 0,02023342 0,03008536 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02023342 0,03006706 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02023342 0,03004878 ! cytolysis GO:0019835 27 22 0,000 0,02023342 0,03003052 ! renal system process GO:0003014 42 22 0,000 0,02023342 0,03001229 ! vasodilation GO:0042311 40 22 0,000 0,02023342 0,02999408 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02023342 0,02997589 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02023342 0,02995772 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02023342 0,02993958 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02023342 0,02992145 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02023342 0,02990335 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02023342 0,02988527 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02023342 0,02986722 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02023342 0,02984918 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02023342 0,02983117 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02023342 0,02981317 ! sarcomere organization GO:0045214 32 22 0,000 0,02023342 0,0297952 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02023342 0,02977725 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02023342 0,02975933 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02023342 0,02974142 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02023342 0,02972354 ! gut development GO:0048565 44 22 0,000 0,02023342 0,02970567 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02023342 0,02968783 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02023342 0,02967001 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02023342 0,02965221 ! protein stabilization GO:0050821 41 22 0,000 0,02023342 0,02963444 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02114362 0,03094899 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02114362 0,03093046 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02114362 0,03091195 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02114362 0,03089346 ! gluconeogenesis GO:0006094 38 23 0,000 0,02114362 0,030875 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02114362 0,03085655 ! viral genome replication GO:0019079 44 23 0,000 0,02114362 0,03083813 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02114362 0,03081973 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02114362 0,03080135 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02114362 0,030783 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02114362 0,03076466 ! regeneration GO:0031099 42 23 0,000 0,02114362 0,03074635 ! axis specification GO:0009798 43 23 0,000 0,02114362 0,03072806 ! visual behavior GO:0007632 46 23 0,000 0,02114362 0,03070979 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02114362 0,03069155 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02114362 0,03067332 ! response to ethanol GO:0045471 47 23 0,000 0,02114362 0,03065512 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02114362 0,03063693 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02114362 0,03061877 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02114362 0,03060063 ! peroxisome organization GO:0007031 43 23 0,000 0,02114362 0,03058252 ! lysosome organization GO:0007040 47 23 0,000 0,02114362 0,03056442 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02114362 0,03054635 ! vesicle targeting GO:0006903 49 23 0,000 0,02114362 0,03052829 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02114362 0,03051026 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02114362 0,03049225 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02114362 0,03047426 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02114362 0,03045629 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02114362 0,03043835 ! DNA modification GO:0006304 36 23 0,000 0,02114362 0,03042042 ! fatty acid transport GO:0015908 47 23 0,000 0,02114362 0,03040251 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02114362 0,03038463 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02114362 0,03036677 ! hormone transport GO:0009914 41 23 0,000 0,02114362 0,03034893 ! cell-cell recognition GO:0009988 28 23 0,000 0,02114362 0,0303311 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02114362 0,0303133 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02114362 0,03029553 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02114362 0,03027777 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02205301 0,03156151 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02205301 0,03154303 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02205301 0,03152458 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02205301 0,03150614 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02205301 0,03148773 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02205301 0,03146933 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02205301 0,03145096 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02205301 0,03143261 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02205301 0,03141429 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02205301 0,03139598 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02205301 0,03137769 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02205301 0,03135943 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02205301 0,03134119 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02205301 0,03132296 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02205301 0,03130476 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02205301 0,03128658 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02205301 0,03126843 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02205301 0,03125029 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02205301 0,03123217 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02205301 0,03121408 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02205301 0,031196 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02205301 0,03117795 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02205301 0,03115992 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02205301 0,03114191 ! membrane depolarization GO:0051899 45 24 0,000 0,02205301 0,03112392 ! pallium development GO:0021543 56 24 0,000 0,02205301 0,03110595 ! oogenesis GO:0048477 44 24 0,000 0,02205301 0,031088 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02205301 0,03107007 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02205301 0,03105216 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02205301 0,03103427 ! platelet activation GO:0030168 41 24 0,000 0,02205301 0,03101641 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02205301 0,03099856 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02205301 0,03098074 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02205301 0,03096293 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02205301 0,03094515 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02205301 0,03092738 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02205301 0,03090964 ! regulation of amine transport GO:0051952 41 24 0,000 0,02205301 0,03089191 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02296157 0,0321462 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02296157 0,03212779 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02296157 0,0321094 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02296157 0,03209103 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02296157 0,03207268 ! phototransduction GO:0007602 37 25 0,000 0,02296157 0,03205436 ! keratinization GO:0031424 37 25 0,000 0,02296157 0,03203605 ! vasculogenesis GO:0001570 49 25 0,000 0,02296157 0,03201777 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02296157 0,0319995 ! vacuole organization GO:0007033 49 25 0,000 0,02296157 0,03198126 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02296157 0,03196303 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02296157 0,03194483 ! receptor metabolic process GO:0043112 53 25 0,000 0,02296157 0,03192665 ! chromosome condensation GO:0030261 48 25 0,000 0,02296157 0,03190849 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02296157 0,03189035 ! regulation of behavior GO:0050795 48 25 0,000 0,02296157 0,03187223 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02296157 0,03185413 ! interaction with host GO:0051701 66 25 0,000 0,02296157 0,03183605 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02296157 0,03181799 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02296157 0,03179996 ! immunoglobulin production GO:0002377 62 25 0,000 0,02296157 0,03178194 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02296157 0,03176394 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02296157 0,03174597 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02296157 0,03172801 ! liver development GO:0001889 55 25 0,000 0,02296157 0,03171008 ! protein tetramerization GO:0051262 57 25 0,000 0,02296157 0,03169216 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02386932 0,03292645 ! myelination GO:0042552 50 26 0,000 0,02386932 0,03290787 ! initiation of viral infection GO:0019059 60 26 0,000 0,02386932 0,03288931 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02386932 0,03287077 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02386932 0,03285225 ! molting cycle process GO:0022404 52 26 0,000 0,02386932 0,03283376 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02386932 0,03281528 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02386932 0,03279682 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02386932 0,03277839 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02386932 0,03275997 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02386932 0,03274158 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02386932 0,0327232 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02386932 0,03270485 ! digestive system process GO:0022600 49 26 0,000 0,02386932 0,03268652 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02386932 0,03266821 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02386932 0,03264992 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02386932 0,03263165 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02386932 0,0326134 ! neural crest cell development GO:0014032 59 26 0,000 0,02386932 0,03259517 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02386932 0,03257696 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02386932 0,03255877 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02386932 0,0325406 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02386932 0,03252245 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02386932 0,03250432 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02386932 0,03248621 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02386932 0,03246812 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02386932 0,03245006 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02386932 0,03243201 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02386932 0,03241398 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02386932 0,03239597 ! blastocyst development GO:0001824 50 26 0,000 0,02386932 0,03237798 ! telomere organization GO:0032200 46 26 0,000 0,02386932 0,03236002 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02386932 0,03234207 ! neural tube closure GO:0001843 58 26 0,000 0,02386932 0,03232414 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,02386932 0,03230623 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02386932 0,03228834 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02386932 0,03227048 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02477625 0,03347809 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02477625 0,03345958 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02477625 0,03344109 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02477625 0,03342263 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02477625 0,03340418 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02477625 0,03338576 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02477625 0,03336735 ! iron ion transport GO:0006826 65 27 0,000 0,02477625 0,03334897 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02477625 0,03333061 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02477625 0,03331226 ! tube lumen formation GO:0035148 59 27 0,000 0,02477625 0,03329394 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02477625 0,03327563 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02477625 0,03325735 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02477625 0,03323909 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02477625 0,03322084 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02477625 0,03320262 ! response to starvation GO:0042594 47 27 0,000 0,02477625 0,03318442 ! response to toxin GO:0009636 49 27 0,000 0,02477625 0,03316624 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02477625 0,03314807 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02477625 0,03312993 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02477625 0,0331118 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02477625 0,0330937 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02477625 0,03307562 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02477625 0,03305755 ! neuron fate commitment GO:0048663 52 28 0,000 0,02568236 0,03424782 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02568236 0,03422914 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02568236 0,03421047 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02568236 0,03419183 ! vesicle docking GO:0048278 55 28 0,000 0,02568236 0,03417321 ! circadian rhythm GO:0007623 56 28 0,000 0,02568236 0,03415461 ! dendrite development GO:0016358 67 28 0,000 0,02568236 0,03413602 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02568236 0,03411746 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02568236 0,03409892 ! sperm motility GO:0030317 37 28 0,000 0,02568236 0,0340804 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02568236 0,0340619 ! base-excision repair GO:0006284 41 28 0,000 0,02568236 0,03404341 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02568236 0,03402495 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02568236 0,03400651 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02568236 0,03398809 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02568236 0,03396969 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02568236 0,0339513 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02568236 0,03393294 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02568236 0,0339146 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02568236 0,03389628 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02568236 0,03387798 ! lipid oxidation GO:0034440 48 28 0,000 0,02568236 0,03385969 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02568236 0,03384143 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02568236 0,03382319 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02658766 0,03499658 ! translational initiation GO:0006413 66 29 0,000 0,02658766 0,03497773 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02658766 0,03495891 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02658766 0,0349401 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02658766 0,03492132 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02658766 0,03490255 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02658766 0,03488381 ! primary neural tube formation GO:0014020 61 29 0,000 0,02658766 0,03486508 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02658766 0,03484638 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02658766 0,03482769 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02658766 0,03480903 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02658766 0,03479038 ! somitogenesis GO:0001756 52 29 0,000 0,02658766 0,03477176 ! synaptogenesis GO:0007416 46 29 0,000 0,02658766 0,03475316 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02658766 0,03473457 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02658766 0,03471601 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02658766 0,03469746 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,02658766 0,03467894 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02749214 0,03583954 ! phenol metabolic process GO:0018958 56 30 0,000 0,02749214 0,03582042 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02749214 0,03580133 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02749214 0,03578226 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02749214 0,0357632 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02749214 0,03574417 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02749214 0,03572516 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02749214 0,03570616 ! acute-phase response GO:0006953 50 30 0,000 0,02749214 0,03568719 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02749214 0,03566824 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02749214 0,03564931 ! myofibril assembly GO:0030239 50 30 0,000 0,02749214 0,03563039 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02749214 0,0356115 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02749214 0,03559263 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02749214 0,03557378 ! cell fate determination GO:0001709 64 30 0,000 0,02749214 0,03555495 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02749214 0,03553613 ! phospholipid transport GO:0015914 65 30 0,000 0,02749214 0,03551734 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02749214 0,03549857 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02749214 0,03547982 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02749214 0,03546108 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02749214 0,03544237 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02749214 0,03542368 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,02749214 0,035405 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0283958 0,0365495 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0283958 0,03653025 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0283958 0,03651102 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0283958 0,03649182 ! cell junction assembly GO:0034329 85 31 0,000 0,0283958 0,03647263 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0283958 0,03645347 ! ovulation cycle process GO:0022602 55 31 0,000 0,0283958 0,03643432 ! peptide transport GO:0015833 60 31 0,000 0,0283958 0,0364152 ! male gonad development GO:0008584 56 31 0,000 0,0283958 0,03639609 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0283958 0,036377 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0283958 0,03635794 ! detection of light stimulus GO:0009583 44 31 0,000 0,0283958 0,03633889 ! natural killer cell activation GO:0030101 50 31 0,000 0,0283958 0,03631987 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0283958 0,03630086 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0283958 0,03628188 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0283958 0,03626291 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0283958 0,03624396 ! eye morphogenesis GO:0048592 65 31 0,000 0,0283958 0,03622504 ! response to heat GO:0009408 54 31 0,000 0,0283958 0,03620613 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0283958 0,03618724 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02929865 0,03731836 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,02929865 0,03729891 ! collagen metabolic process GO:0032963 49 32 0,000 0,02929865 0,03727948 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02929865 0,03726008 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02929865 0,03724069 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02929865 0,03722133 ! metanephros development GO:0001656 81 32 0,000 0,02929865 0,03720198 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02929865 0,03718265 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,02929865 0,03716335 ! muscle cell development GO:0055001 52 32 0,000 0,02929865 0,03714406 ! mesoderm formation GO:0001707 73 32 0,000 0,02929865 0,0371248 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,02929865 0,03710555 ! ovulation cycle GO:0042698 57 32 0,000 0,02929865 0,03708633 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02929865 0,03706712 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02929865 0,03704794 ! hindbrain development GO:0030902 65 32 0,000 0,02929865 0,03702877 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02929865 0,03700962 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02929865 0,0369905 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02929865 0,03697139 ! gene silencing GO:0016458 71 32 0,000 0,02929865 0,0369523 ! regulation of pH GO:0006885 56 33 0,000 0,03020069 0,03807032 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03020069 0,03805069 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03020069 0,03803108 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03020069 0,03801148 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03020069 0,03799191 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03020069 0,03797236 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03020069 0,03795282 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03020069 0,03793331 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03020069 0,03791382 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03020069 0,03789434 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03020069 0,03787489 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03020069 0,03785546 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03020069 0,03783604 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03020069 0,03781665 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03020069 0,03779728 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03110192 0,03890526 ! glial cell differentiation GO:0010001 67 34 0,000 0,03110192 0,03888535 ! post-embryonic development GO:0009791 76 34 0,000 0,03110192 0,03886546 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03110192 0,03884559 ! cholesterol transport GO:0030301 62 34 0,000 0,03110192 0,03882574 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03110192 0,03880591 ! spliceosome assembly GO:0000245 75 34 0,000 0,03110192 0,0387861 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03110192 0,03876632 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03110192 0,03874655 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03110192 0,0387268 ! cell fate specification GO:0001708 56 34 0,000 0,03110192 0,03870707 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03110192 0,03868736 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03110192 0,03866767 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03110192 0,03864801 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03110192 0,03862836 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03200233 0,03972647 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03200233 0,03970629 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03200233 0,03968613 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03200233 0,039666 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03200233 0,03964589 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03200233 0,03962579 ! membrane docking GO:0022406 69 35 0,000 0,03200233 0,03960572 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03200233 0,03958566 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03200233 0,03956563 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03200233 0,03954562 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03200233 0,03952562 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03200233 0,03950565 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03200233 0,0394857 ! telencephalon development GO:0021537 81 35 0,000 0,03200233 0,03946577 ! sterol transport GO:0015918 63 35 0,000 0,03200233 0,03944586 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03200233 0,03942596 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03200233 0,03940609 ! placenta development GO:0001890 53 35 0,000 0,03200233 0,03938624 ! vesicle localization GO:0051648 70 35 0,000 0,03200233 0,03936641 ! regulation of muscle development GO:0048634 82 36 0,000 0,03290193 0,04045265 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03290193 0,0404323 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,03290193 0,04041197 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03290193 0,04039166 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03290193 0,04037138 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03290193 0,04035111 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03290193 0,04033086 ! protein targeting to membrane GO:0006612 75 36 0,000 0,03290193 0,04031064 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03290193 0,04029043 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,03290193 0,04027025 ! aerobic respiration GO:0009060 56 36 0,000 0,03290193 0,04025008 ! cytokine production GO:0001816 68 36 0,000 0,03290193 0,04022994 ! embryonic organ development GO:0048568 67 36 0,000 0,03290193 0,04020981 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03290193 0,04018971 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,03290193 0,04016962 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,03380072 0,04124633 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,03380072 0,04122574 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,03380072 0,04120517 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,03380072 0,04118462 ! sister chromatid segregation GO:0000819 65 37 0,000 0,03380072 0,04116408 ! odontogenesis GO:0042476 74 37 0,000 0,03380072 0,04114357 ! actomyosin structure organization GO:0031032 68 37 0,000 0,03380072 0,04112308 ! cell junction organization GO:0034330 96 37 0,000 0,03380072 0,04110262 ! tissue remodeling GO:0048771 78 37 0,000 0,03380072 0,04108217 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,03380072 0,04106174 ! female gonad development GO:0008585 71 37 0,000 0,03380072 0,04104133 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,03380072 0,04102094 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,03380072 0,04100057 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,03380072 0,04098023 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,0346987 0,04204808 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,0346987 0,04202723 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,0346987 0,0420064 ! organic anion transport GO:0015711 82 38 0,000 0,0346987 0,0419856 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,0346987 0,04196481 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,0346987 0,04194405 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,0346987 0,0419233 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,0346987 0,04190258 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,0346987 0,04188188 ! regulation of protein stability GO:0031647 77 38 0,000 0,0346987 0,04186119 ! spermatid development GO:0007286 69 38 0,000 0,0346987 0,04184053 ! glycogen metabolic process GO:0005977 63 38 0,000 0,0346987 0,04181989 ! pigment metabolic process GO:0042440 87 38 0,000 0,0346987 0,04179927 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,0346987 0,04177867 ! neural tube formation GO:0001841 79 38 0,000 0,0346987 0,04175809 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03559587 0,0428167 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03559587 0,04279562 ! negative regulation of binding GO:0051100 71 39 0,000 0,03559587 0,04277457 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03559587 0,04275354 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03559587 0,04273253 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03559587 0,04271155 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03559587 0,04269058 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03559587 0,04266963 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03559587 0,0426487 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03559587 0,0426278 ! glucan metabolic process GO:0044042 64 39 0,000 0,03559587 0,04260691 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03649223 0,04365843 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03649223 0,04363706 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03649223 0,04361571 ! learning GO:0007612 82 40 0,000 0,03649223 0,04359439 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03649223 0,04357308 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,03649223 0,04355179 ! lipid homeostasis GO:0055088 75 40 0,000 0,03649223 0,04353053 ! mismatch repair GO:0006298 58 40 0,000 0,03649223 0,04350928 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03649223 0,04348806 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03649223 0,04346686 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,03649223 0,04344567 ! RNA export from nucleus GO:0006405 61 41 0,000 0,03738779 0,04449019 ! mRNA catabolic process GO:0006402 79 41 0,000 0,03738779 0,04446853 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,03738779 0,04444689 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,03738779 0,04442527 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,03738779 0,04440367 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,03738779 0,0443821 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,03738779 0,04436054 ! gliogenesis GO:0042063 91 41 0,000 0,03738779 0,04433901 ! feeding behavior GO:0007631 69 41 0,000 0,03738779 0,0443175 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,03738779 0,044296 ! mesenchymal cell development GO:0014031 94 41 0,000 0,03738779 0,04427453 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,03738779 0,04425308 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,03738779 0,04423165 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,03738779 0,04421024 ! spermatid differentiation GO:0048515 73 41 0,000 0,03738779 0,04418885 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,03738779 0,04416749 ! RNA modification GO:0009451 64 41 0,000 0,03738779 0,04414614 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,03828253 0,04518079 ! ear morphogenesis GO:0042471 64 42 0,000 0,03828253 0,04515897 ! organic ether metabolic process GO:0018904 59 42 0,000 0,03828253 0,04513717 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,03828253 0,0451154 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,03828253 0,04509365 ! T cell differentiation GO:0030217 93 42 0,000 0,03828253 0,04507192 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,03828253 0,04505021 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,03828253 0,04502852 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,03828253 0,04500685 ! regulation of protein secretion GO:0050708 77 42 0,000 0,03828253 0,0449852 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,03828253 0,04496357 ! cytokinesis GO:0000910 84 42 0,000 0,03828253 0,04494196 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,03828253 0,04492038 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,03917647 0,04594725 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,03917647 0,0459252 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,03917647 0,04590318 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,03917647 0,04588117 ! regulation of tube size GO:0035150 76 43 0,000 0,03917647 0,04585919 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,03917647 0,04583722 ! glucose transport GO:0015758 66 43 0,000 0,03917647 0,04581528 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,03917647 0,04579336 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,03917647 0,04577146 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,03917647 0,04574958 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,03917647 0,04572772 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,03917647 0,04570588 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,03917647 0,04568407 ! segmentation GO:0035282 78 43 0,000 0,03917647 0,04566227 ! ion transmembrane transport GO:0034220 79 43 0,000 0,03917647 0,0456405 ! neuron migration GO:0001764 85 43 0,000 0,03917647 0,04561874 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,03917647 0,04559701 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,04006961 0,04661431 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,04006961 0,04659212 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,04006961 0,04656996 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,04006961 0,04654781 ! hexose transport GO:0008645 68 44 0,000 0,04006961 0,04652569 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,04006961 0,04650359 ! striated muscle contraction GO:0006941 85 44 0,000 0,04006961 0,04648151 ! phagocytosis GO:0006909 105 44 0,000 0,04006961 0,04645945 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,04006961 0,04643741 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,04096194 0,04744903 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,04096194 0,04742655 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,04096194 0,04740408 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,04096194 0,04738163 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,04096194 0,04735921 ! biopolymer methylation GO:0043414 91 45 0,000 0,04096194 0,04733681 ! B cell differentiation GO:0030183 124 45 0,000 0,04096194 0,04731443 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,04096194 0,04729207 ! female gamete generation GO:0007292 71 45 0,000 0,04096194 0,04726973 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,04096194 0,04724741 ! polyol metabolic process GO:0019751 77 45 0,000 0,04096194 0,04722511 ! developmental growth GO:0048589 88 45 0,000 0,04096194 0,04720284 ! maintenance of location in cell GO:0051651 101 45 0,000 0,04096194 0,04718058 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,04185346 0,04818474 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,04185346 0,04816204 ! glycolysis GO:0006096 71 46 0,000 0,04185346 0,04813936 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,04185346 0,04811671 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,04185346 0,04809408 ! leukocyte migration GO:0050900 75 46 0,000 0,04185346 0,04807147 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,04185346 0,04804888 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,04185346 0,04802631 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,04185346 0,04800376 ! pigmentation GO:0043473 103 46 0,000 0,04185346 0,04798123 ! cell growth GO:0016049 90 46 0,000 0,04185346 0,04795873 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,04185346 0,04793624 ! neural tube development GO:0021915 91 47 0,000 0,04274418 0,04893348 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04274418 0,04891056 ! response to insulin stimulus GO:0032868 98 47 0,000 0,04274418 0,04888766 ! positive regulation of defense response GO:0031349 88 48 0,000 0,0436341 0,04988213 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,0436341 0,0498588 ! mitochondrial transport GO:0006839 94 48 0,000 0,0436341 0,04983549 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,0436341 0,0498122 ! cellular component disassembly GO:0022411 89 48 0,000 0,0436341 0,04978894 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,0436341 0,04976569 ! endosome transport GO:0016197 127 48 0,000 0,0436341 0,04974247 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,0436341 0,04971927 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,0436341 0,04969609 ! male sex differentiation GO:0046661 93 48 0,000 0,0436341 0,04967293 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,0436341 0,0496498 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,0436341 0,04962668 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,0436341 0,04960359 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,0436341 0,04958052 ! methylation GO:0032259 97 48 0,000 0,0436341 0,04955747 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,04452322 0,05054378 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,04452322 0,05052031 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,04452322 0,05049685 ! JNK cascade GO:0007254 106 49 0,000 0,04452322 0,05047342 ! protein homooligomerization GO:0051260 84 49 0,000 0,04452322 0,05045001 ! regulation of action potential GO:0001508 102 50 0,000 0,04541153 0,05143272 ! regulation of ion transport GO:0043269 86 50 0,000 0,04541153 0,05140889 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,04541153 0,05138508 ! endocrine system development GO:0035270 109 50 0,000 0,04541153 0,05136129 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,04541153 0,05133752 ! regulation of ossification GO:0030278 123 50 0,000 0,04541153 0,05131377 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,04541153 0,05129005 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,04541153 0,05126635 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,04541153 0,05124267 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,04541153 0,05121901 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,04541153 0,05119537 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,04629905 0,05217185 ! viral infectious cycle GO:0019058 104 51 0,000 0,04629905 0,0521478 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,04629905 0,05212377 ! peptide metabolic process GO:0006518 80 51 0,000 0,04629905 0,05209976 ! response to temperature stimulus GO:0009266 84 51 0,000 0,04629905 0,05207577 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,04629905 0,05205181 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,04629905 0,05202786 ! positive regulation of binding GO:0051099 88 52 0,000 0,04718576 0,05299992 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,04718576 0,05297556 ! Notch signaling pathway GO:0007219 111 52 0,000 0,04718576 0,05295122 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,04718576 0,05292691 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,04718576 0,05290262 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,04718576 0,05287836 ! excretion GO:0007588 87 52 0,000 0,04718576 0,05285411 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,04718576 0,05282989 ! histone modification GO:0016570 104 52 0,000 0,04718576 0,05280569 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,04718576 0,05278151 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,04718576 0,05275735 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,04718576 0,05273322 ! amino acid activation GO:0043038 98 52 0,000 0,04718576 0,05270911 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,04807168 0,05367418 ! positive regulation of growth GO:0045927 96 53 0,000 0,04807168 0,05364966 ! inner ear development GO:0048839 89 53 0,000 0,04807168 0,05362516 ! chromatin remodeling GO:0006338 122 53 0,000 0,04807168 0,05360069 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,04807168 0,05357623 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,04807168 0,0535518 ! vesicle organization GO:0016050 127 53 0,000 0,04807168 0,05352739 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,04807168 0,05350301 ! cartilage development GO:0051216 99 53 0,000 0,04807168 0,05347864 ! synapse organization GO:0050808 102 53 0,000 0,04807168 0,0534543 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,04895679 0,05441376 ! regulation of translational initiation GO:0006446 87 54 0,000 0,04895679 0,05438901 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,04895679 0,05436429 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,04895679 0,05433959 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,04895679 0,05431491 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,04895679 0,05429026 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,04895679 0,05426563 ! membrane fusion GO:0006944 122 54 0,000 0,04895679 0,05424102 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,04895679 0,05421643 ! covalent chromatin modification GO:0016569 115 54 0,000 0,04895679 0,05419186 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,04895679 0,05416732 ! regulation of cell shape GO:0008360 142 54 0,000 0,04895679 0,0541428 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,04895679 0,0541183 ! RNA catabolic process GO:0006401 103 55 0,000 0,04984111 0,05507093 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,04984111 0,05504603 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,04984111 0,05502116 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,04984111 0,05499631 ! cell recognition GO:0008037 98 55 0,000 0,04984111 0,05497148 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,04984111 0,05494667 ! cell maturation GO:0048469 107 55 0,000 0,04984111 0,05492189 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,04984111 0,05489713 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,04984111 0,05487239 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,05072463 0,05581994 ! glucose catabolic process GO:0006007 88 56 0,000 0,05072463 0,05579481 ! regulation of DNA replication GO:0006275 105 56 0,000 0,05072463 0,0557697 ! RNA elongation GO:0006354 90 56 0,000 0,05072463 0,05574461 ! chloride transport GO:0006821 102 57 0,000 0,05160735 0,05668919 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,05160735 0,05666371 ! muscle fiber development GO:0048747 131 57 0,000 0,05160735 0,05663826 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,05160735 0,05661283 ! heart morphogenesis GO:0003007 105 57 0,000 0,05160735 0,05658742 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,05160735 0,05656203 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,05160735 0,05653666 ! regulation of actin filament length GO:0030832 118 58 0,000 0,05248928 0,05747706 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,05248928 0,0574513 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,05248928 0,05742558 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,05248928 0,05739987 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,05248928 0,05737419 ! aging GO:0007568 112 58 0,000 0,05248928 0,05734853 ! gastrulation GO:0007369 122 58 0,000 0,05248928 0,05732289 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,05248928 0,05729728 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,05248928 0,05727169 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,05248928 0,05724612 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,05248928 0,05722058 ! maintenance of location GO:0051235 124 58 0,000 0,05248928 0,05719505 ! nuclear export GO:0051168 110 59 0,000 0,05337041 0,05812925 ! establishment of organelle localization GO:0051656 122 59 0,000 0,05337041 0,05810335 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,05425075 0,05903545 ! lipid modification GO:0030258 112 60 0,000 0,05425075 0,05900916 ! DNA catabolic process GO:0006308 94 60 0,000 0,05425075 0,0589829 ! regulation of endocytosis GO:0030100 104 60 0,000 0,05425075 0,05895666 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,05425075 0,05893045 ! adult behavior GO:0030534 104 60 0,000 0,05425075 0,05890426 ! kidney development GO:0001822 133 60 0,000 0,05425075 0,05887809 ! positive regulation of secretion GO:0051047 110 61 0,000 0,05513029 0,05980609 ! regulation of cellular component size GO:0032535 125 61 0,000 0,05513029 0,05977954 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,05513029 0,05975302 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,05513029 0,05972652 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,05513029 0,05970005 ! regulation of heart contraction GO:0008016 123 61 0,000 0,05513029 0,0596736 ! camera-type eye development GO:0043010 126 61 0,000 0,05513029 0,05964717 ! proton transport GO:0015992 117 61 0,000 0,05513029 0,05962076 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,05513029 0,05959438 ! viral reproductive process GO:0022415 132 62 0,000 0,05600904 0,06051751 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,05600904 0,06049076 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,05600904 0,06046403 ! tRNA processing GO:0008033 102 62 0,000 0,05600904 0,06043732 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,05600904 0,06041064 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,056887 0,06133051 ! regulation of mitosis GO:0007088 112 63 0,000 0,056887 0,06130346 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,056887 0,06127643 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,056887 0,06124942 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,056887 0,06122244 ! hydrogen transport GO:0006818 121 64 0,000 0,05776417 0,06213908 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,05776417 0,06211173 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,05776417 0,06208441 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,05776417 0,06205711 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,05776417 0,06202983 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,05864054 0,06294325 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,05864054 0,06291561 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,05864054 0,06288799 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,05864054 0,0628604 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,05864054 0,06283283 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,05864054 0,06280528 ! ear development GO:0043583 114 66 0,000 0,05951613 0,06371512 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,05951613 0,06368721 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,05951613 0,06365932 ! gonad development GO:0008406 115 66 0,000 0,05951613 0,06363146 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,05951613 0,06360363 ! activation of MAPK activity GO:0000187 124 67 0,000 0,06039092 0,06451028 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,06039092 0,06448209 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,06039092 0,06445392 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,06039092 0,06442577 ! secondary metabolic process GO:0019748 125 67 0,000 0,06039092 0,06439765 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,06039092 0,06436956 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,06126493 0,06527266 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,06126493 0,06524421 ! hexose catabolic process GO:0019320 113 68 0,000 0,06126493 0,06521578 ! extracellular matrix organization GO:0030198 146 68 0,000 0,06126493 0,06518738 ! detection of external stimulus GO:0009581 102 68 0,000 0,06126493 0,065159 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,06126493 0,06513064 ! viral reproduction GO:0016032 142 68 0,000 0,06126493 0,06510231 ! regulation of lipase activity GO:0060191 137 68 0,000 0,06126493 0,06507401 ! adaptive immune response GO:0002250 126 68 0,000 0,06126493 0,06504573 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,06126493 0,06501747 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,06213814 0,06591554 ! lung development GO:0030324 165 69 0,000 0,06213814 0,06588693 ! urogenital system development GO:0001655 149 69 0,000 0,06213814 0,06585835 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,06213814 0,06582979 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,06213814 0,06580125 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,06213814 0,06577274 ! developmental maturation GO:0021700 128 69 0,000 0,06213814 0,06574426 ! single fertilization GO:0007338 83 69 0,000 0,06213814 0,06571579 ! cell redox homeostasis GO:0045454 114 70 0,000 0,06301057 0,06660962 ! germ cell development GO:0007281 133 70 0,000 0,06301057 0,06658081 ! activation of immune response GO:0002253 120 70 0,000 0,06301057 0,06655202 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,06301057 0,06652326 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,06388222 0,06741436 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,06388222 0,06738526 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,06388222 0,06735617 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,06388222 0,06732712 ! appendage morphogenesis GO:0035107 150 72 0,000 0,06475307 0,06821551 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,06475307 0,0681861 ! respiratory tube development GO:0030323 171 72 0,000 0,06475307 0,06815672 ! actin filament organization GO:0007015 167 72 0,000 0,06475307 0,06812737 ! B cell activation GO:0042113 179 72 0,000 0,06475307 0,06809804 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,06475307 0,06806874 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,06475307 0,06803947 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,06475307 0,06801021 ! appendage development GO:0048736 151 73 0,000 0,06562314 0,06889443 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,06562314 0,06886484 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,06562314 0,06883527 ! regulation of immune effector process GO:0002697 156 73 0,000 0,06562314 0,06880573 ! acute inflammatory response GO:0002526 118 74 0,000 0,06649243 0,06968726 ! amino acid transport GO:0006865 148 74 0,000 0,06649243 0,06965738 ! respiratory system development GO:0060541 175 74 0,000 0,06649243 0,06962752 ! organelle localization GO:0051640 155 74 0,000 0,06649243 0,06959769 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,06736093 0,07047655 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,06736093 0,07044638 ! reproductive structure development GO:0048608 131 75 0,000 0,06736093 0,07041624 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,06736093 0,07038612 ! eye development GO:0001654 155 75 0,000 0,06736093 0,07035603 ! axon guidance GO:0007411 162 75 0,000 0,06736093 0,07032596 ! rhythmic process GO:0048511 142 75 0,000 0,06736093 0,07029592 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,06822865 0,07117105 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,06822865 0,07114067 ! learning or memory GO:0007611 161 76 0,000 0,06822865 0,07111032 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,06822865 0,07108 ! regulation of blood pressure GO:0008217 134 76 0,000 0,06822865 0,0710497 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,06822865 0,07101942 ! amine catabolic process GO:0009310 136 77 0,000 0,06909558 0,07189119 ! neurotransmitter transport GO:0006836 142 77 0,000 0,06909558 0,07186058 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,06909558 0,07183001 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,06909558 0,07179945 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,06909558 0,07176893 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,06909558 0,07173842 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,06996174 0,07260685 ! antigen processing and presentation GO:0019882 117 78 0,000 0,06996174 0,07257602 ! fertilization GO:0009566 99 78 0,000 0,06996174 0,07254521 ! blood coagulation GO:0007596 151 79 0,000 0,07082711 0,07341138 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,07082711 0,07338025 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,07082711 0,07334914 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,07082711 0,07331806 ! protein oligomerization GO:0051259 149 79 0,000 0,07082711 0,07328701 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,07082711 0,07325598 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,0716917 0,07411884 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,0716917 0,07408749 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,0716917 0,07405616 ! muscle cell differentiation GO:0042692 178 81 0,000 0,07255551 0,07491678 ! response to hypoxia GO:0001666 178 81 0,000 0,07255551 0,07488513 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,07255551 0,07485351 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,07341854 0,0757119 ! protein import into nucleus GO:0006606 174 82 0,000 0,07341854 0,07567996 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,07428079 0,07653647 ! exocytosis GO:0006887 153 83 0,000 0,07428079 0,07650421 ! response to drug GO:0042493 149 83 0,000 0,07428079 0,07647197 ! response to oxygen levels GO:0070482 183 83 0,000 0,07428079 0,07643975 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,07428079 0,07640757 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,07428079 0,07637541 ! nuclear import GO:0051170 177 83 0,000 0,07428079 0,07634328 ! T cell activation GO:0042110 189 84 0,000 0,07514227 0,0771962 ! response to nutrient GO:0007584 135 84 0,000 0,07514227 0,07716375 ! digestion GO:0007586 130 84 0,000 0,07514227 0,07713133 ! hemostasis GO:0007599 165 85 0,000 0,07600296 0,07798204 ! negative regulation of transport GO:0051051 164 85 0,000 0,07600296 0,0779493 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,07600296 0,07791659 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,07600296 0,07788391 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,07600296 0,07785125 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,07600296 0,07781863 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,07600296 0,07778602 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,07686288 0,07863318 ! regulation of lyase activity GO:0051339 169 86 0,000 0,07686288 0,07860026 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,07772203 0,07944557 ! mitochondrion organization GO:0007005 159 87 0,000 0,07772203 0,07941234 ! alcohol catabolic process GO:0046164 142 87 0,000 0,07772203 0,07937914 ! nucleosome assembly GO:0006334 126 87 0,000 0,07772203 0,07934597 ! regulation of protein transport GO:0051223 165 87 0,000 0,07772203 0,07931283 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,0785804 0,08015528 ! amine biosynthetic process GO:0009309 146 88 0,000 0,0785804 0,08012183 ! sensory perception of smell GO:0007608 117 88 0,000 0,0785804 0,08008841 ! chromatin assembly GO:0031497 128 88 0,000 0,0785804 0,08005501 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,0785804 0,08002164 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,07943799 0,08086125 ! regulation of DNA binding GO:0051101 167 89 0,000 0,07943799 0,08082758 ! tube morphogenesis GO:0035239 194 89 0,000 0,07943799 0,08079393 ! cellular defense response GO:0006968 123 89 0,000 0,07943799 0,0807603 ! protein localization in nucleus GO:0034504 192 89 0,000 0,07943799 0,08072671 ! regulation of neurological system process GO:0031644 175 89 0,000 0,07943799 0,08069314 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,08029481 0,0815296 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,08029481 0,08149573 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,08115086 0,08233037 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,08115086 0,0822962 ! gland development GO:0048732 220 91 0,000 0,08115086 0,08226205 ! defense response to bacterium GO:0042742 112 91 0,000 0,08115086 0,08222793 ! bone development GO:0060348 206 92 0,000 0,08200613 0,08306011 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,08200613 0,08302568 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,08200613 0,08299129 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,08286063 0,08382133 ! amine transport GO:0015837 181 93 0,000 0,08286063 0,08378664 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,08286063 0,08375197 ! vitamin metabolic process GO:0006766 153 93 0,000 0,08286063 0,08371734 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,08371436 0,08454493 ! female pregnancy GO:0007565 166 94 0,000 0,08371436 0,08450999 ! sterol metabolic process GO:0016125 166 94 0,000 0,08371436 0,08447509 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,08371436 0,08444021 ! regulation of membrane potential GO:0042391 179 94 0,000 0,08371436 0,08440536 ! regulation of defense response GO:0031347 171 95 0,000 0,08456732 0,08523018 ! nucleosome organization GO:0034728 143 95 0,000 0,08456732 0,08519504 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,08456732 0,08515992 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,08456732 0,08512483 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,08456732 0,08508977 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,08456732 0,08505474 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,08456732 0,08501974 ! sex differentiation GO:0007548 171 96 0,000 0,08541951 0,08584116 ! regulation of T cell activation GO:0050863 175 96 0,000 0,08541951 0,08580587 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,08627093 0,08662552 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,08627093 0,08658993 ! transcription initiation GO:0006352 171 97 0,000 0,08627093 0,08655437 ! regulation of protein localization GO:0032880 188 97 0,000 0,08627093 0,08651884 ! leukocyte differentiation GO:0002521 232 98 0,000 0,08712158 0,08733608 ! forebrain development GO:0030900 210 98 0,000 0,08712158 0,08730026 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,08712158 0,08726447 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,08882058 0,08892979 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,08882058 0,08889336 ! positive regulation of immune response GO:0050778 175 100 0,000 0,08882058 0,08885696 ! hormone metabolic process GO:0042445 171 100 0,000 0,08882058 0,08882058