pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/7407-9-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 4,55E-08 1,046E-04 GO:0019405|alditol catabolic process, ! response to unfolded protein GO:0006986 99 76 4,000 1,779E-07 2,045E-04 ! response to protein stimulus GO:0051789 111 81 4,000 2,452E-07 1,88E-04 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 7,455E-07 4,287E-04 ! fructose metabolic process GO:0006000 20 16 2,000 2,515E-06 1,157E-03 ! alditol metabolic process GO:0019400 24 20 2,000 5,097E-06 1,954E-03 ! sperm motility GO:0030317 27 24 2,000 9,008E-06 2,96E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 1,617E-05 4,648E-03 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 2,187E-05 5,589E-03 ! polyol metabolic process GO:0019751 44 34 2,000 2,633E-05 6,055E-03 ! amino acid activation GO:0043038 52 37 2,000 3,406E-05 7,122E-03 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! alcohol biosynthetic process GO:0046165 45 38 2,000 3,694E-05 7,08E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 4,252E-05 7,523E-03 GO:0046530|photoreceptor cell differentiation, ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 4,252E-05 6,985E-03 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,759E-05 8,831E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,947E-05 8,548E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 1,000 5,947E-05 8,045E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 5,947E-05 7,598E-03 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 5,947E-05 7,198E-03 ! regulation of neuron apoptosis GO:0043523 77 47 2,000 7,027E-05 8,081E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 7,92E-05 8,675E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! keratinocyte proliferation GO:0043616 12 8 1,000 7,92E-05 8,28E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 7,92E-05 7,92E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,983E-05 8,609E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 1,017E-04 9,358E-03 ! establishment of cell polarity GO:0030010 12 9 1,000 1,017E-04 8,999E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 1,27E-04 0,01082 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 1,535E-04 0,01260543 ! Golgi vesicle budding GO:0048194 17 11 1,000 1,551E-04 0,01229928 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 1,611E-04 0,01234899 ! regulation of caspase activity GO:0043281 97 65 2,000 1,854E-04 0,0137545 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 1,854E-04 0,01332467 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 1,854E-04 0,0129209 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,859E-04 0,01257524 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 2,028E-04 0,01333006 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 2,195E-04 0,01402103 ! positive regulation of ligase activity GO:0051351 99 69 2,000 2,213E-04 0,01375923 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 2,409E-04 0,01458077 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,511E-04 0,01480746 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,558E-04 0,01470637 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 1,000 2,558E-04 0,01434768 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,558E-04 0,01400607 ! response to nutrient GO:0007584 104 75 2,000 2,833E-04 0,01515293 ! regulation of ligase activity GO:0051340 114 75 2,000 2,833E-04 0,01480855 ! tRNA metabolic process GO:0006399 95 76 2,000 2,946E-04 0,01505709 ! positive regulation of cell size GO:0045793 20 15 1,000 2,948E-04 0,01473982 ! skin development GO:0043588 25 15 1,000 2,948E-04 0,01442621 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,948E-04 0,01412566 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 3,062E-04 0,0143719 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,366E-04 0,01548134 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of protein binding GO:0043393 27 16 1,000 3,366E-04 0,01517778 ! alcohol catabolic process GO:0046164 104 80 2,000 3,427E-04 0,01515816 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 3,427E-04 0,01487216 GO:0010498|proteasomal protein catabolic process, ! negative regulation of peptidase activity GO:0010466 23 17 1,000 3,81E-04 0,01622852 ! membrane budding GO:0006900 29 17 1,000 3,81E-04 0,01593346 ! cell-cell junction organization GO:0045216 25 17 1,000 3,81E-04 0,01564893 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 4,239E-04 0,01710595 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 4,282E-04 0,01697985 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,282E-04 0,01669205 ! visual learning GO:0008542 35 18 1,000 4,282E-04 0,01641385 ! interphase GO:0051325 159 88 2,000 4,535E-04 0,01709984 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 4,781E-04 0,01773419 ! response to lipopolysaccharide GO:0032496 26 19 1,000 4,781E-04 0,0174527 ! carbohydrate catabolic process GO:0016052 121 93 2,000 5,332E-04 0,01916212 ! response to light stimulus GO:0009416 153 96 2,000 5,851E-04 0,02070213 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,858E-04 0,0204153 ! visual behavior GO:0007632 39 21 1,000 5,858E-04 0,0201106 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 5,858E-04 0,01981485 ! cell aging GO:0007569 32 21 1,000 5,858E-04 0,01952768 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,858E-04 0,01924871 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,043E-04 0,02281478 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,043E-04 0,0224979 ! osteoblast differentiation GO:0001649 40 23 1,000 7,043E-04 0,02218971 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 7,043E-04 0,02188985 ! fat cell differentiation GO:0045444 37 24 1,000 7,675E-04 0,02353633 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 9,729E-04 0,0294439 ! protein targeting to membrane GO:0006612 53 29 1,000 1,123E-03 0,03354372 ! eye morphogenesis GO:0048592 51 29 1,000 1,123E-03 0,03311367 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 1,368E-03 0,03981456 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 1,454E-03 0,04180888 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 63 33 1,000 1,454E-03 0,04129272 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,454E-03 0,04078915 ! mRNA catabolic process GO:0006402 48 34 1,000 1,543E-03 0,04277073 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 1,543E-03 0,04226156 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,635E-03 0,04424837 ! learning GO:0007612 67 37 1,000 1,827E-03 0,04884834 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,926E-03 0,05091521 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 2,028E-03 0,05300106 ! response to calcium ion GO:0051592 58 40 1,000 2,132E-03 0,05510502 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 2,132E-03 0,05449274 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,132E-03 0,05389392 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 2,461E-03 0,0615176 ! activation of caspase activity GO:0006919 65 43 1,000 2,461E-03 0,06085612 ! vesicle organization GO:0016050 79 43 1,000 2,461E-03 0,06020872 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,692E-03 0,06517583 ! RNA catabolic process GO:0006401 64 45 1,000 2,692E-03 0,06449691 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 2,692E-03 0,06383199 ! response to UV GO:0009411 75 46 1,000 2,811E-03 0,06598224 ! positive regulation of caspase activity GO:0043280 72 48 1,000 3,058E-03 0,07103337 GO:0010952|positive regulation of peptidase activity, ! positive regulation of growth GO:0045927 67 50 1,000 3,313E-03 0,07620799 ! aging GO:0007568 79 52 1,000 3,579E-03 0,08150095 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 3,854E-03 0,0869073 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,139E-03 0,09242229 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 4,285E-03 0,09476131 ! negative regulation of kinase activity GO:0033673 100 58 1,000 4,433E-03 0,09710764 ! actin filament organization GO:0007015 95 59 1,000 4,584E-03 0,09946089 ! negative regulation of transferase activity GO:0051348 105 61 1,000 4,892E-03 0,10516044 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,372E-03 0,11441092 ! protein oligomerization GO:0051259 100 65 1,000 5,537E-03 0,11683587 ! learning or memory GO:0007611 123 68 1,000 6,045E-03 0,12639111 ! activation of protein kinase activity GO:0032147 102 69 1,000 6,219E-03 0,12885443 ! response to metal ion GO:0010038 103 70 1,000 6,395E-03 0,13132042 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 6,395E-03 0,1301583 ! eye development GO:0001654 111 70 1,000 6,395E-03 0,12901656 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 6,395E-03 0,12789467 ! muscle cell differentiation GO:0042692 104 71 1,000 6,573E-03 0,13032882 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 6,754E-03 0,13276573 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 1,000 6,754E-03 0,1316406 ! mitochondrion organization GO:0007005 104 73 1,000 6,937E-03 0,134069 ! response to inorganic substance GO:0010035 115 75 1,000 7,309E-03 0,14009087 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 7,69E-03 0,14618247 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 7,69E-03 0,14498425 ! positive regulation of protein modification process GO:0031401 107 78 1,000 7,884E-03 0,14743336 ! regulation of cyclase activity GO:0031279 132 78 1,000 7,884E-03 0,14624438 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 8,081E-03 0,14868477 ! regulation of lyase activity GO:0051339 133 79 1,000 8,081E-03 0,14750473 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 8,48E-03 0,15356941 ! regulation of neurological system process GO:0031644 122 81 1,000 8,48E-03 0,15236965 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,552E-03 0,15247451 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,552E-03 0,15130163 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,552E-03 0,15014666 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,552E-03 0,14900918 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,552E-03 0,14788881 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,552E-03 0,14678516 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,552E-03 0,14569787 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,552E-03 0,14462656 ! sleep GO:0030431 11 5 0,000 8,552E-03 0,14357089 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,552E-03 0,14253052 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,552E-03 0,14150512 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,552E-03 0,14049437 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,552E-03 0,13949796 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,552E-03 0,13851558 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,552E-03 0,13754694 ! tongue development GO:0043586 6 5 0,000 8,552E-03 0,13659175 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,552E-03 0,13564974 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,552E-03 0,13472063 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,552E-03 0,13380416 ! cobalt ion transport GO:0006824 9 5 0,000 8,552E-03 0,13290008 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,552E-03 0,13200813 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,552E-03 0,13112808 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,552E-03 0,13025968 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,552E-03 0,12940271 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,552E-03 0,12855694 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,552E-03 0,12772215 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,552E-03 0,12689814 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,552E-03 0,12608469 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,552E-03 0,1252816 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,552E-03 0,12448868 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,552E-03 0,12370573 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,552E-03 0,12293257 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,552E-03 0,12216902 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,552E-03 0,12141489 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,552E-03 0,12067001 ! malate metabolic process GO:0006108 7 5 0,000 8,552E-03 0,11993422 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,552E-03 0,11920734 ! behavioral response to pain GO:0048266 7 5 0,000 8,552E-03 0,11848923 ! clathrin coat assembly GO:0048268 11 5 0,000 8,552E-03 0,11777971 ! phototransduction, visible light GO:0007603 6 5 0,000 8,552E-03 0,11707864 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,552E-03 0,11638587 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,552E-03 0,11570125 ! mating behavior GO:0007617 6 5 0,000 8,552E-03 0,11502463 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,552E-03 0,11435588 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,552E-03 0,11369487 ! rhythmic behavior GO:0007622 12 5 0,000 8,552E-03 0,11304145 ! copulation GO:0007620 7 5 0,000 8,552E-03 0,1123955 ! glial cell fate commitment GO:0021781 12 5 0,000 8,552E-03 0,11175689 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,552E-03 0,11112549 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,552E-03 0,11050119 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,552E-03 0,10988386 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,552E-03 0,1092734 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,552E-03 0,10866968 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,552E-03 0,10807259 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,552E-03 0,10748203 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,552E-03 0,10689789 ! response to protozoan GO:0001562 9 5 0,000 8,552E-03 0,10632006 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,552E-03 0,10574845 ! lymph vessel development GO:0001945 7 5 0,000 8,552E-03 0,10518295 ! endochondral ossification GO:0001958 12 5 0,000 8,552E-03 0,10462347 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,552E-03 0,1040699 ! parathyroid gland development GO:0060017 8 5 0,000 8,552E-03 0,10352217 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,552E-03 0,10298017 ! anagen GO:0042640 6 5 0,000 8,552E-03 0,10244381 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,552E-03 0,10191301 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,552E-03 0,10138769 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,552E-03 0,10086775 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,552E-03 0,10035312 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,552E-03 0,09984371 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,552E-03 0,09933945 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 8,552E-03 0,09884026 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,552E-03 0,09834606 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,552E-03 0,09785678 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,552E-03 0,09737234 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,552E-03 0,09689267 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 8,552E-03 0,0964177 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,552E-03 0,09594737 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,552E-03 0,09548161 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,552E-03 0,09502035 ! ovulation GO:0030728 6 5 0,000 8,552E-03 0,09456352 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,552E-03 0,09411106 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,552E-03 0,09366291 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,552E-03 0,09321901 ! response to pH GO:0009268 9 5 0,000 8,552E-03 0,0927793 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,552E-03 0,09234372 ! proline biosynthetic process GO:0006561 6 5 0,000 8,552E-03 0,0919122 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,552E-03 0,09148471 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,552E-03 0,09106117 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,552E-03 0,09064153 ! polyol biosynthetic process GO:0046173 5 5 0,000 8,552E-03 0,09022574 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,552E-03 0,08981375 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,552E-03 0,08940551 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,552E-03 0,08900096 ! nerve growth factor processing GO:0032455 7 5 0,000 8,552E-03 0,08860005 ! urea metabolic process GO:0019627 6 5 0,000 8,552E-03 0,08820274 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,552E-03 0,08780898 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,552E-03 0,08741872 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,552E-03 0,08703191 ! neutrophil activation GO:0042119 5 5 0,000 8,552E-03 0,08664851 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,552E-03 0,08626847 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,552E-03 0,08589175 ! response to food GO:0032094 5 5 0,000 8,552E-03 0,08551831 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,552E-03 0,0851481 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,552E-03 0,08478109 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,552E-03 0,08441722 ! forebrain neuron development GO:0021884 7 5 0,000 8,552E-03 0,08405646 ! melanosome organization GO:0032438 7 5 0,000 8,552E-03 0,08369877 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,552E-03 0,08334412 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,552E-03 0,08299245 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,552E-03 0,08264375 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,552E-03 0,08229796 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,552E-03 0,08195505 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,552E-03 0,08161499 ! nucleoside transport GO:0015858 6 5 0,000 8,552E-03 0,08127773 ! nucleoside salvage GO:0043174 7 5 0,000 8,552E-03 0,08094326 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 8,552E-03 0,08061152 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,552E-03 0,0802825 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,552E-03 0,07995615 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,552E-03 0,07963244 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,552E-03 0,07931134 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,552E-03 0,07899282 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,552E-03 0,07867685 ! depyrimidination GO:0045008 8 5 0,000 8,552E-03 0,07836339 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,552E-03 0,07805243 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,552E-03 0,07774392 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,552E-03 0,07743784 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,552E-03 0,07713416 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,552E-03 0,07683286 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,552E-03 0,0765339 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,552E-03 0,07623726 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,552E-03 0,0759429 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,552E-03 0,07565081 ! monocyte differentiation GO:0030224 8 5 0,000 8,552E-03 0,07536096 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,552E-03 0,07507333 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,552E-03 0,07478788 ! centrosome duplication GO:0051298 5 5 0,000 8,552E-03 0,07450459 ! response to UV-C GO:0010225 6 5 0,000 8,552E-03 0,07422344 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,552E-03 0,07394441 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,552E-03 0,07366746 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,552E-03 0,07339258 ! regulation of dendrite development GO:0050773 12 5 0,000 8,552E-03 0,07311975 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,552E-03 0,07284893 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,552E-03 0,07258012 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,552E-03 0,07231328 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,552E-03 0,07204839 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,552E-03 0,07178544 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,552E-03 0,07152441 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,552E-03 0,07126526 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,552E-03 0,07100798 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,552E-03 0,07075256 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,552E-03 0,07049897 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,552E-03 0,07024719 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,552E-03 0,0699972 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,552E-03 0,06974898 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,552E-03 0,06950252 ! neural tube patterning GO:0021532 6 5 0,000 8,552E-03 0,06925779 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,552E-03 0,06901478 ! histone demethylation GO:0016577 9 5 0,000 8,552E-03 0,06877347 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,552E-03 0,06853384 ! regulation of sterol transport GO:0032371 7 5 0,000 8,552E-03 0,06829587 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,552E-03 0,06805956 ! enteric nervous system development GO:0048484 8 5 0,000 8,552E-03 0,06782487 ! establishment of planar polarity GO:0001736 6 5 0,000 8,552E-03 0,06759179 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,552E-03 0,06736031 ! muscle cell proliferation GO:0033002 8 5 0,000 8,552E-03 0,06713042 ! transcription termination GO:0006353 8 5 0,000 8,552E-03 0,06690208 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,552E-03 0,06667529 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,552E-03 0,06645004 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,552E-03 0,0662263 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,552E-03 0,06600407 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,552E-03 0,06578332 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,552E-03 0,06556404 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,552E-03 0,06534622 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,552E-03 0,06512984 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,552E-03 0,06491489 ! apical protein localization GO:0045176 6 5 0,000 8,552E-03 0,06470135 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,552E-03 0,06448922 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,552E-03 0,06427847 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,552E-03 0,06406909 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,552E-03 0,06386108 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,552E-03 0,06365441 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,552E-03 0,06344907 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,552E-03 0,06324505 ! glial cell migration GO:0008347 10 5 0,000 8,552E-03 0,06304235 ! determination of adult lifespan GO:0008340 8 5 0,000 8,552E-03 0,06284093 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,552E-03 0,0626408 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,552E-03 0,06244194 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,552E-03 0,06224434 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,552E-03 0,06204799 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,552E-03 0,06185287 ! neural plate development GO:0001840 6 5 0,000 8,552E-03 0,06165897 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,552E-03 0,06146629 ! regulation of sensory perception GO:0051931 6 5 0,000 8,552E-03 0,0612748 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,552E-03 0,06108451 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,552E-03 0,06089539 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,552E-03 0,06070744 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,552E-03 0,06052065 ! sensory cilium assembly GO:0035058 6 5 0,000 8,552E-03 0,06033501 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,552E-03 0,06015049 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,552E-03 0,05996711 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,552E-03 0,05978484 ! spindle assembly GO:0051225 5 5 0,000 8,552E-03 0,05960367 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,552E-03 0,0594236 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,552E-03 0,05924461 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,552E-03 0,0590667 ! organ regeneration GO:0031100 7 5 0,000 8,552E-03 0,05888986 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,552E-03 0,05871407 ! carnitine metabolic process GO:0009437 5 5 0,000 8,552E-03 0,05853932 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,552E-03 0,05836561 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,552E-03 0,05819293 GO:0055081|anion homeostasis, ! ossification GO:0001503 134 82 1,000 8,682E-03 0,05890769 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 8,887E-03 0,06012087 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! Golgi vesicle transport GO:0048193 138 85 1,000 9,304E-03 0,06275308 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 9,515E-03 0,06399146 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,01016236 0,0681441 ! tRNA transcription GO:0009304 11 6 0,000 0,01025369 0,06855667 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01025369 0,06835796 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01025369 0,06816039 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01025369 0,06796396 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01025369 0,06776866 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01025369 0,06757448 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01025369 0,06738141 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01025369 0,06718944 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01025369 0,06699856 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01025369 0,06680877 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01025369 0,06662004 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01025369 0,06643238 ! prostate gland development GO:0030850 9 6 0,000 0,01025369 0,06624577 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01025369 0,06606021 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01025369 0,06587568 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01025369 0,06569219 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01025369 0,06550971 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01025369 0,06532824 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01025369 0,06514778 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01025369 0,06496831 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01025369 0,06478982 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01025369 0,06461231 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01025369 0,06443578 ! neuron adhesion GO:0007158 9 6 0,000 0,01025369 0,0642602 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01025369 0,06408558 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01025369 0,06391191 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01025369 0,06373918 ! signal peptide processing GO:0006465 8 6 0,000 0,01025369 0,06356737 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01025369 0,06339649 ! mRNA stabilization GO:0048255 15 6 0,000 0,01025369 0,06322653 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01025369 0,06305747 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01025369 0,06288932 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01025369 0,06272206 ! opsonization GO:0008228 8 6 0,000 0,01025369 0,06255569 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01025369 0,0623902 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01025369 0,06222558 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01025369 0,06206183 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01025369 0,06189894 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01025369 0,0617369 ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01025369 0,0615757 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01025369 0,06141535 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01025369 0,06125583 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01025369 0,06109714 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01025369 0,06093926 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01025369 0,0607822 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01025369 0,06062595 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01025369 0,0604705 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01025369 0,06031584 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01025369 0,06016198 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01025369 0,06000889 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01025369 0,05985659 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01025369 0,05970505 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01025369 0,05955428 ! thymic T cell selection GO:0045061 12 6 0,000 0,01025369 0,05940427 ! protein lipoylation GO:0009249 10 6 0,000 0,01025369 0,05925501 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01025369 0,0591065 ! pigment granule organization GO:0048753 11 6 0,000 0,01025369 0,05895874 ! drug transport GO:0015893 6 6 0,000 0,01025369 0,05881171 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01025369 0,05866541 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01025369 0,05851984 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01025369 0,05837499 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01025369 0,05823085 ! histidine metabolic process GO:0006547 6 6 0,000 0,01025369 0,05808743 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01025369 0,0579447 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01025369 0,05780268 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01025369 0,05766136 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01025369 0,05752072 ! adenohypophysis development GO:0021984 10 6 0,000 0,01025369 0,05738077 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01025369 0,05724149 ! hyperosmotic response GO:0006972 8 6 0,000 0,01025369 0,05710289 ! microtubule nucleation GO:0007020 10 6 0,000 0,01025369 0,05696496 ! ER overload response GO:0006983 7 6 0,000 0,01025369 0,0568277 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01025369 0,05669109 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01025369 0,05655514 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01025369 0,05641984 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01025369 0,05628519 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01025369 0,05615118 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01025369 0,0560178 ! response to dietary excess GO:0002021 7 6 0,000 0,01025369 0,05588506 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01025369 0,05575294 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01025369 0,05562145 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01025369 0,05549058 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01025369 0,05536032 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01025369 0,05523067 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01025369 0,05510162 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01025369 0,05497318 ! neuron apoptosis GO:0051402 8 6 0,000 0,01025369 0,05484534 ! organic alcohol transport GO:0015850 9 6 0,000 0,01025369 0,05471809 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01025369 0,05459142 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01025369 0,05446535 ! male sex determination GO:0030238 9 6 0,000 0,01025369 0,05433985 ! carnitine transport GO:0015879 8 6 0,000 0,01025369 0,05421493 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01025369 0,05409058 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01025369 0,05396681 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01025369 0,0538436 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01025369 0,05372094 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01025369 0,05359885 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01025369 0,05347731 ! parturition GO:0007567 12 6 0,000 0,01025369 0,05335632 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01025369 0,05323588 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01025369 0,05311598 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01025369 0,05299662 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01025369 0,05287779 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01025369 0,0527595 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01025369 0,05264173 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01025369 0,05252449 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01025369 0,05240777 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01025369 0,05229156 ! macrophage differentiation GO:0030225 10 6 0,000 0,01025369 0,05217587 ! astrocyte development GO:0014002 14 6 0,000 0,01025369 0,05206069 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01025369 0,05194602 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01025369 0,05183186 ! interaction with symbiont GO:0051702 8 6 0,000 0,01025369 0,05171819 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01025369 0,05160502 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01025369 0,05149235 ! eating behavior GO:0042755 6 6 0,000 0,01025369 0,05138016 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01025369 0,05126847 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01025369 0,05115726 ! response to copper ion GO:0046688 9 6 0,000 0,01025369 0,05104653 ! DNA topological change GO:0006265 8 6 0,000 0,01025369 0,05093627 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01025369 0,0508265 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01025369 0,05071719 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01025369 0,05060836 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01025369 0,05049999 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01025369 0,05039208 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01025369 0,05028464 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01025369 0,05017765 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01025369 0,05007111 ! gas homeostasis GO:0033483 11 6 0,000 0,01025369 0,04996503 ! hair follicle maturation GO:0048820 7 6 0,000 0,01025369 0,0498594 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01025369 0,04975421 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01025369 0,04964946 ! Schwann cell development GO:0014044 14 6 0,000 0,01025369 0,04954516 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01025369 0,04944129 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01025369 0,04933786 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01025369 0,04923485 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01025369 0,04913228 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01025369 0,04903013 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01025369 0,04892841 ! histone ubiquitination GO:0016574 7 6 0,000 0,01025369 0,04882711 ! regulation of meiosis GO:0040020 10 6 0,000 0,01025369 0,04872623 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01025369 0,04862576 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01025369 0,04852571 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01025369 0,04842607 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01025369 0,04832683 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01025369 0,04822801 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01025369 0,04812958 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01025369 0,04803156 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01025369 0,04793393 ! receptor internalization GO:0031623 9 6 0,000 0,01025369 0,0478367 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01025369 0,04773987 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01025369 0,04764342 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01025369 0,04754737 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01025369 0,0474517 ! protein deubiquitination GO:0016579 8 6 0,000 0,01025369 0,04735642 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01025369 0,04726151 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01025369 0,04716699 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01025369 0,04707284 ! axonal fasciculation GO:0007413 9 6 0,000 0,01025369 0,04697907 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01025369 0,04688568 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01025369 0,04679265 ! midbrain development GO:0030901 6 6 0,000 0,01025369 0,04669999 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01025369 0,0466077 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01025369 0,04651577 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01025369 0,0464242 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01025369 0,046333 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01025369 0,04624215 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01025369 0,04615165 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01025369 0,04606151 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01025369 0,04597172 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01025369 0,04588229 ! adult feeding behavior GO:0008343 6 6 0,000 0,01025369 0,04579319 ! blastocyst growth GO:0001832 15 6 0,000 0,01025369 0,04570445 ! pigment granule transport GO:0051904 12 6 0,000 0,01025369 0,04561604 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01025369 0,04552798 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01025369 0,04544026 ! catecholamine transport GO:0051937 7 6 0,000 0,01025369 0,04535287 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01025369 0,04526582 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01025369 0,04517911 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01025369 0,04509272 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01025369 0,04500667 ! protein prenylation GO:0018342 10 6 0,000 0,01025369 0,04492094 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01025369 0,04483554 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01025369 0,04475046 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01025369 0,04466571 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01025369 0,04458128 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01025369 0,04449716 ! regulation of binding GO:0051098 151 95 1,000 0,01151363 0,04987072 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01195273 0,05167534 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01195273 0,05157839 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01195273 0,0514818 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01195273 0,05138557 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01195273 0,05128971 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01195273 0,05119419 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01195273 0,05109904 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01195273 0,05100423 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01195273 0,05090978 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01195273 0,05081568 ! reproductive behavior GO:0019098 12 7 0,000 0,01195273 0,05072192 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01195273 0,05062851 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01195273 0,05053545 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01195273 0,05044272 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01195273 0,05035033 ! oligopeptide transport GO:0006857 11 7 0,000 0,01195273 0,05025829 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01195273 0,05016657 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01195273 0,0500752 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01195273 0,04998415 ! RNA methylation GO:0001510 11 7 0,000 0,01195273 0,04989343 ! pericardium development GO:0060039 8 7 0,000 0,01195273 0,04980305 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01195273 0,04971299 ! fibril organization GO:0043206 13 7 0,000 0,01195273 0,04962325 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01195273 0,04953384 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01195273 0,04944475 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01195273 0,04935598 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01195273 0,04926753 ! lipoprotein transport GO:0042953 9 7 0,000 0,01195273 0,0491794 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01195273 0,04909158 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01195273 0,04900407 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01195273 0,04891687 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01195273 0,04882999 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01195273 0,04874341 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01195273 0,04865714 ! chemosensory behavior GO:0007635 9 7 0,000 0,01195273 0,04857117 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01195273 0,04848551 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01195273 0,04840014 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01195273 0,04831508 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01195273 0,04823032 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01195273 0,04814585 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01195273 0,04806168 ! reflex GO:0060004 12 7 0,000 0,01195273 0,04797781 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01195273 0,04789422 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01195273 0,04781093 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01195273 0,04772792 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01195273 0,0476452 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01195273 0,04756277 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01195273 0,04748063 ! spinal cord patterning GO:0021511 7 7 0,000 0,01195273 0,04739876 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01195273 0,04731718 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01195273 0,04723588 ! adrenal gland development GO:0030325 17 7 0,000 0,01195273 0,04715486 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01195273 0,04707411 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01195273 0,04699365 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01195273 0,04691345 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01195273 0,04683353 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01195273 0,04675388 ! endosome organization GO:0007032 10 7 0,000 0,01195273 0,0466745 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01195273 0,04659539 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01195273 0,04651655 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01195273 0,04643798 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01195273 0,04635967 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01195273 0,04628162 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01195273 0,04620384 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01195273 0,04612631 ! galactose metabolic process GO:0006012 10 7 0,000 0,01195273 0,04604905 ! vesicle fusion GO:0006906 15 7 0,000 0,01195273 0,04597204 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01195273 0,0458953 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01195273 0,0458188 ! organ growth GO:0035265 11 7 0,000 0,01195273 0,04574257 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01195273 0,04566658 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01195273 0,04559085 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01195273 0,04551537 ! retinol metabolic process GO:0042572 9 7 0,000 0,01195273 0,04544014 ! behavioral fear response GO:0001662 13 7 0,000 0,01195273 0,04536515 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01195273 0,04529042 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01195273 0,04521592 ! rRNA modification GO:0000154 12 7 0,000 0,01195273 0,04514168 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01195273 0,04506768 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01195273 0,04499392 ! response to UV-B GO:0010224 11 7 0,000 0,01195273 0,0449204 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01195273 0,04484712 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01195273 0,04477408 ! intermediate filament organization GO:0045109 11 7 0,000 0,01195273 0,04470127 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01195273 0,04462871 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01195273 0,04455637 ! fibrinolysis GO:0042730 9 7 0,000 0,01195273 0,04448428 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01195273 0,04441241 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01195273 0,04434078 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01195273 0,04426938 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01195273 0,0441982 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01195273 0,04412726 ! response to tropane GO:0014073 13 7 0,000 0,01195273 0,04405654 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01195273 0,04398605 ! melanosome localization GO:0032400 10 7 0,000 0,01195273 0,04391579 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01195273 0,04384575 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01195273 0,04377593 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01195273 0,04370633 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01195273 0,04363696 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01195273 0,0435678 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01195273 0,04349886 ! mast cell activation GO:0045576 9 7 0,000 0,01195273 0,04343015 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01195273 0,04336164 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01195273 0,04329336 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01195273 0,04322529 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01195273 0,04315743 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01195273 0,04308978 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01195273 0,04302235 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01195273 0,04295513 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01195273 0,04288812 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01195273 0,04282131 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01195273 0,04275472 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01195273 0,04268833 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01195273 0,04262214 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01195273 0,04255616 ! response to tumor cell GO:0002347 12 7 0,000 0,01195273 0,04249039 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01195273 0,04242482 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01195273 0,04235945 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01195273 0,04229428 ! diuresis GO:0030146 12 7 0,000 0,01195273 0,04222931 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01195273 0,04216454 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01195273 0,04209997 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01195273 0,0420356 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01195273 0,04197142 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01195273 0,04190744 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01195273 0,04184366 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01195273 0,04178006 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01195273 0,04171667 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01195273 0,04165346 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01195273 0,04159044 ! lymph node development GO:0048535 9 7 0,000 0,01195273 0,04152762 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01195273 0,04146498 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01195273 0,04140253 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01195273 0,04134027 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01195273 0,0412782 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01195273 0,04121632 ! ATP catabolic process GO:0006200 10 7 0,000 0,01195273 0,04115461 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01195273 0,0410931 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01195273 0,04103176 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01195273 0,04097061 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01195273 0,04090965 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01195273 0,04084886 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01195273 0,04078825 ! muscle adaptation GO:0043500 12 7 0,000 0,01195273 0,04072783 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01195273 0,04066758 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01195273 0,04060751 ! retina homeostasis GO:0001895 9 7 0,000 0,01195273 0,04054761 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01195273 0,0404879 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01195273 0,04042836 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01195273 0,04036899 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01195273 0,0403098 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01195273 0,04025078 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01195273 0,04019193 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01195273 0,04013326 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,01198075 0,04016868 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,01269687 0,0425077 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01364895 0,04562876 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01364895 0,04556253 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01364895 0,0454965 ! axon extension GO:0048675 11 8 0,000 0,01364895 0,04543066 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01364895 0,04536501 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01364895 0,04529955 ! associative learning GO:0008306 15 8 0,000 0,01364895 0,04523427 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01364895 0,04516919 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01364895 0,04510429 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01364895 0,04503958 ! phosphate transport GO:0006817 10 8 0,000 0,01364895 0,04497505 ! N-glycan processing GO:0006491 12 8 0,000 0,01364895 0,04491071 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01364895 0,04484655 ! UTP metabolic process GO:0046051 8 8 0,000 0,01364895 0,04478257 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01364895 0,04471878 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01364895 0,04465517 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01364895 0,04459174 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01364895 0,04452849 ! succinate metabolic process GO:0006105 14 8 0,000 0,01364895 0,04446542 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01364895 0,04440252 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01364895 0,04433981 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01364895 0,04427727 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01364895 0,04421491 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01364895 0,04415272 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01364895 0,04409071 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01364895 0,04402887 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01364895 0,04396721 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01364895 0,04390571 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01364895 0,04384439 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01364895 0,04378324 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01364895 0,04372226 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01364895 0,04366145 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01364895 0,04360081 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01364895 0,04354034 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01364895 0,04348003 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01364895 0,0434199 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01364895 0,04335992 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01364895 0,04330012 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01364895 0,04324048 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01364895 0,043181 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01364895 0,04312168 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01364895 0,04306253 ! melanin metabolic process GO:0006582 12 8 0,000 0,01364895 0,04300354 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01364895 0,04294471 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01364895 0,04288604 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01364895 0,04282754 ! macrophage activation GO:0042116 12 8 0,000 0,01364895 0,04276919 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01364895 0,042711 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01364895 0,04265297 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01364895 0,04259509 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01364895 0,04253738 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01364895 0,04247982 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01364895 0,04242241 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01364895 0,04236516 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01364895 0,04230807 ! ruffle organization GO:0031529 11 8 0,000 0,01364895 0,04225112 ! osteoblast development GO:0002076 13 8 0,000 0,01364895 0,04219433 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01364895 0,0421377 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01364895 0,04208121 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01364895 0,04202488 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01364895 0,0419687 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01364895 0,04191266 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01364895 0,04185678 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01364895 0,04180105 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01364895 0,04174546 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01364895 0,04169002 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01364895 0,04163473 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01364895 0,04157958 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01364895 0,04152458 ! segment specification GO:0007379 10 8 0,000 0,01364895 0,04146973 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01364895 0,04141502 ! cellular extravasation GO:0045123 11 8 0,000 0,01364895 0,04136045 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01364895 0,04130603 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01364895 0,04125175 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01364895 0,04119762 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01364895 0,04114362 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01364895 0,04108977 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01364895 0,04103606 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01364895 0,04098249 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01364895 0,04092905 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01364895 0,04087576 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01364895 0,04082261 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01364895 0,04076959 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01364895 0,04071671 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01364895 0,04066397 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01364895 0,04061136 ! icosanoid secretion GO:0032309 12 8 0,000 0,01364895 0,0405589 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01364895 0,04050656 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01364895 0,04045436 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01364895 0,0404023 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01364895 0,04035037 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01364895 0,04029857 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01364895 0,0402469 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01364895 0,04019537 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01364895 0,04014397 ! sterol catabolic process GO:0016127 9 8 0,000 0,01364895 0,0400927 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01364895 0,04004156 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01364895 0,03999055 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01364895 0,03993968 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01364895 0,03988893 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01364895 0,03983831 ! prophase GO:0051324 11 8 0,000 0,01364895 0,03978781 ! S phase GO:0051320 8 8 0,000 0,01364895 0,03973745 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01364895 0,03968721 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01364895 0,0396371 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01364895 0,03958712 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01364895 0,03953726 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01364895 0,03948753 ! hormone catabolic process GO:0042447 13 8 0,000 0,01364895 0,03943792 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01364895 0,03938844 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01364895 0,03933908 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01364895 0,03928984 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01364895 0,03924073 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01364895 0,03919174 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01364895 0,03914287 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01364895 0,03909413 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01364895 0,0390455 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01364895 0,038997 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01364895 0,03894862 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01364895 0,03890035 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01364895 0,03885221 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01364895 0,03880418 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01364895 0,03875628 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01364895 0,03870849 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01534235 0,0434574 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01534235 0,04340395 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01534235 0,04335063 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01534235 0,04329744 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01534235 0,04324438 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01534235 0,04319145 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01534235 0,04313865 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01534235 0,04308597 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01534235 0,04303343 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01534235 0,04298101 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01534235 0,04292873 ! GTP metabolic process GO:0046039 9 9 0,000 0,01534235 0,04287656 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01534235 0,04282453 ! social behavior GO:0035176 14 9 0,000 0,01534235 0,04277262 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01534235 0,04272084 ! artery development GO:0060840 19 9 0,000 0,01534235 0,04266918 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01534235 0,04261765 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01534235 0,04256624 ! response to pain GO:0048265 16 9 0,000 0,01534235 0,04251496 ! protein complex disassembly GO:0043241 17 9 0,000 0,01534235 0,04246379 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01534235 0,04241276 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01534235 0,04236184 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01534235 0,04231105 ! lung alveolus development GO:0048286 17 9 0,000 0,01534235 0,04226037 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01534235 0,04220982 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01534235 0,04215939 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01534235 0,04210908 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01534235 0,04205889 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01534235 0,04200882 ! protein targeting to ER GO:0045047 19 9 0,000 0,01534235 0,04195887 ! T cell selection GO:0045058 18 9 0,000 0,01534235 0,04190904 ! endoderm development GO:0007492 12 9 0,000 0,01534235 0,04185933 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01534235 0,04180973 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01534235 0,04176025 ! arginine catabolic process GO:0006527 10 9 0,000 0,01534235 0,04171089 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01534235 0,04166164 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01534235 0,04161252 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01534235 0,0415635 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01534235 0,0415146 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01534235 0,04146582 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01534235 0,04141715 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01534235 0,0413686 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01534235 0,04132016 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01534235 0,04127183 ! mannose metabolic process GO:0006013 9 9 0,000 0,01534235 0,04122361 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01534235 0,04117551 ! receptor clustering GO:0043113 15 9 0,000 0,01534235 0,04112752 ! epithelial cell development GO:0002064 10 9 0,000 0,01534235 0,04107964 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01534235 0,04103188 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01534235 0,04098422 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01534235 0,04093667 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01534235 0,04088924 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01534235 0,04084191 ! motor axon guidance GO:0008045 14 9 0,000 0,01534235 0,0407947 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01534235 0,04074759 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01534235 0,04070059 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01534235 0,0406537 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01534235 0,04060692 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01534235 0,04056024 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01534235 0,04051368 ! DNA ligation GO:0006266 14 9 0,000 0,01534235 0,04046722 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01534235 0,04042086 ! response to amine stimulus GO:0014075 13 9 0,000 0,01534235 0,04037461 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01534235 0,04032847 ! erythrocyte development GO:0048821 11 9 0,000 0,01534235 0,04028243 ! renal water homeostasis GO:0003091 14 9 0,000 0,01534235 0,0402365 ! postreplication repair GO:0006301 11 9 0,000 0,01534235 0,04019068 ! mRNA cleavage GO:0006379 13 9 0,000 0,01534235 0,04014495 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01534235 0,04009933 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01534235 0,04005382 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01534235 0,0400084 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01534235 0,03996309 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01534235 0,03991789 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01534235 0,03987278 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01534235 0,03982778 ! acid secretion GO:0046717 14 9 0,000 0,01534235 0,03978288 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01534235 0,03973808 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01534235 0,03969338 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01534235 0,03964878 ! purine base metabolic process GO:0006144 18 9 0,000 0,01534235 0,03960428 ! oocyte differentiation GO:0009994 12 9 0,000 0,01534235 0,03955988 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01534235 0,03951558 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01534235 0,03947138 ! spleen development GO:0048536 15 9 0,000 0,01534235 0,03942728 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01534235 0,03938327 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01534235 0,03933937 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01534235 0,03929556 ! detection of calcium ion GO:0005513 13 9 0,000 0,01534235 0,03925185 ! blastocyst formation GO:0001825 12 9 0,000 0,01534235 0,03920824 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01534235 0,03916472 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01534235 0,0391213 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01534235 0,03907798 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01534235 0,03903475 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01534235 0,03899162 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01534235 0,03894858 ! prepulse inhibition GO:0060134 14 9 0,000 0,01534235 0,03890564 ! embryonic placenta development GO:0001892 12 9 0,000 0,01534235 0,03886279 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01534235 0,03882004 ! insulin secretion GO:0030073 17 9 0,000 0,01534235 0,03877738 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01534235 0,03873481 ! response to nicotine GO:0035094 16 9 0,000 0,01534235 0,03869234 ! nucleus localization GO:0051647 15 9 0,000 0,01534235 0,03864996 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01534235 0,03860767 ! localization within membrane GO:0051668 15 9 0,000 0,01534235 0,03856548 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01703295 0,04276831 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01703295 0,04272168 ! neuron fate specification GO:0048665 11 10 0,000 0,01703295 0,04267514 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01703295 0,0426287 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01703295 0,04258237 ! thyroid gland development GO:0030878 19 10 0,000 0,01703295 0,04253613 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01703295 0,04249 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01703295 0,04244396 ! synapsis GO:0007129 13 10 0,000 0,01703295 0,04239803 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01703295 0,04235219 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01703295 0,04230645 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01703295 0,04226082 ! sulfate transport GO:0008272 12 10 0,000 0,01703295 0,04221528 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01703295 0,04216983 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01703295 0,04212449 ! androgen metabolic process GO:0008209 13 10 0,000 0,01703295 0,04207924 ! phospholipid efflux GO:0033700 16 10 0,000 0,01703295 0,04203409 ! hippocampus development GO:0021766 19 10 0,000 0,01703295 0,04198904 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01703295 0,04194409 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01703295 0,04189923 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01703295 0,04185446 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01703295 0,04180979 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01703295 0,04176522 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01703295 0,04172074 ! pathogenesis GO:0009405 13 10 0,000 0,01703295 0,04167636 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01703295 0,04163207 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01703295 0,04158787 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01703295 0,04154377 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01703295 0,04149976 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01703295 0,04145585 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01703295 0,04141203 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01703295 0,0413683 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01703295 0,04132466 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01703295 0,04128111 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01703295 0,04123766 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01703295 0,0411943 ! response to X-ray GO:0010165 16 10 0,000 0,01703295 0,04115103 ! B cell proliferation GO:0042100 14 10 0,000 0,01703295 0,04110785 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01703295 0,04106476 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01703295 0,04102176 ! forebrain cell migration GO:0021885 17 10 0,000 0,01703295 0,04097885 ! lipid digestion GO:0044241 15 10 0,000 0,01703295 0,04093603 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01703295 0,04089329 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01703295 0,04085065 ! UV protection GO:0009650 14 10 0,000 0,01703295 0,0408081 ! entry into host cell GO:0030260 20 10 0,000 0,01703295 0,04076564 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01703295 0,04072326 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01703295 0,04068097 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01703295 0,04063877 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01703295 0,04059666 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01703295 0,04055463 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01703295 0,0405127 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01703295 0,04047084 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01703295 0,04042908 ! regulation of organ growth GO:0046620 11 10 0,000 0,01703295 0,0403874 ! response to dsRNA GO:0043331 18 10 0,000 0,01703295 0,0403458 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01703295 0,0403043 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01703295 0,04026287 ! embryonic axis specification GO:0000578 12 10 0,000 0,01703295 0,04022154 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01703295 0,04018028 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01703295 0,04013912 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01703295 0,04009803 ! cranial nerve development GO:0021545 12 10 0,000 0,01703295 0,04005703 ! fucose catabolic process GO:0019317 16 10 0,000 0,01703295 0,04001611 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01703295 0,03997528 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01703295 0,03993453 ! protein sumoylation GO:0016925 12 10 0,000 0,01703295 0,03989387 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01703295 0,03985328 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01703295 0,03981278 ! zymogen activation GO:0031638 14 10 0,000 0,01703295 0,03977236 ! salivary gland development GO:0007431 22 10 0,000 0,01703295 0,03973202 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01703295 0,03969177 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01703295 0,0396516 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01703295 0,0396115 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01703295 0,03957149 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01703295 0,03953156 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01703295 0,03949171 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01703295 0,03945194 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01703295 0,03941225 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01703295 0,03937264 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01703295 0,03933311 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01703295 0,03929366 ! detection of bacterium GO:0016045 10 10 0,000 0,01703295 0,03925428 ! embryonic gut development GO:0048566 11 10 0,000 0,01703295 0,03921499 ! activation of innate immune response GO:0002218 10 10 0,000 0,01703295 0,03917578 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01703295 0,03913664 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01703295 0,03909758 ! developmental induction GO:0031128 13 10 0,000 0,01703295 0,0390586 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01703295 0,0390197 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01703295 0,03898087 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01703295 0,03894212 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01703295 0,03890345 ! rRNA transcription GO:0009303 17 11 0,000 0,01872073 0,04271596 ! respiratory burst GO:0045730 14 11 0,000 0,01872073 0,04267362 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01872073 0,04263137 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01872073 0,0425892 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01872073 0,04254712 ! virus-host interaction GO:0019048 17 11 0,000 0,01872073 0,04250512 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01872073 0,0424632 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01872073 0,04242137 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01872073 0,04237961 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01872073 0,04233794 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01872073 0,04229635 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01872073 0,04225484 ! mating GO:0007618 14 11 0,000 0,01872073 0,04221342 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01872073 0,04217207 ! T cell proliferation GO:0042098 20 11 0,000 0,01872073 0,04213081 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01872073 0,04208962 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01872073 0,04204852 ! bone resorption GO:0045453 16 11 0,000 0,01872073 0,0420075 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01872073 0,04196656 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01872073 0,04192569 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01872073 0,04188491 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01872073 0,0418442 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01872073 0,04180358 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01872073 0,04176303 ! syncytium formation GO:0006949 15 11 0,000 0,01872073 0,04172256 ! plasma membrane organization GO:0007009 18 11 0,000 0,01872073 0,04168217 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01872073 0,04164186 ! focal adhesion formation GO:0048041 24 11 0,000 0,01872073 0,04160163 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01872073 0,04156147 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01872073 0,04152139 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01872073 0,04148139 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01872073 0,04144147 ! adult heart development GO:0007512 11 11 0,000 0,01872073 0,04140162 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01872073 0,04136185 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01872073 0,04132216 ! temperature homeostasis GO:0001659 16 11 0,000 0,01872073 0,04128254 ! L-glutamate transport GO:0015813 16 11 0,000 0,01872073 0,04124299 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01872073 0,04120353 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01872073 0,04116414 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01872073 0,04112482 ! stem cell development GO:0048864 29 11 0,000 0,01872073 0,04108558 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01872073 0,04104641 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01872073 0,04100732 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01872073 0,0409683 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01872073 0,04092936 ! vasoconstriction GO:0042310 15 11 0,000 0,01872073 0,04089049 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01872073 0,04085169 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01872073 0,04081297 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01872073 0,04077432 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01872073 0,04073575 ! ribosome assembly GO:0042255 13 11 0,000 0,01872073 0,04069725 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01872073 0,04065882 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01872073 0,04062046 ! chromatin silencing GO:0006342 19 11 0,000 0,01872073 0,04058217 ! nucleosome positioning GO:0016584 13 11 0,000 0,01872073 0,04054396 ! T cell homeostasis GO:0043029 20 11 0,000 0,01872073 0,04050582 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01872073 0,04046775 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01872073 0,04042975 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01872073 0,04039183 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01872073 0,04035397 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01872073 0,04031619 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01872073 0,04027847 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01872073 0,04024083 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01872073 0,04020325 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01872073 0,04016575 ! male genitalia development GO:0030539 13 11 0,000 0,01872073 0,04012832 ! cholesterol efflux GO:0033344 19 11 0,000 0,01872073 0,04009096 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01872073 0,04005366 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01872073 0,04001644 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01872073 0,03997928 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01872073 0,03994219 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01872073 0,03990518 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01872073 0,03986823 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01872073 0,03983135 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01872073 0,03979453 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01872073 0,03975779 ! lysogeny GO:0030069 18 11 0,000 0,01872073 0,03972111 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01872073 0,0396845 ! acrosome reaction GO:0007340 13 11 0,000 0,01872073 0,03964796 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01872073 0,03961149 ! lactation GO:0007595 20 12 0,000 0,02040572 0,04313709 ! reproductive cellular process GO:0048610 14 12 0,000 0,02040572 0,04309748 ! tRNA modification GO:0006400 14 12 0,000 0,02040572 0,04305794 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02040572 0,04301847 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02040572 0,04297908 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02040572 0,04293976 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02040572 0,0429005 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02040572 0,04286133 ! non-recombinational repair GO:0000726 19 12 0,000 0,02040572 0,04282222 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02040572 0,04278318 ! peroxisomal transport GO:0043574 21 12 0,000 0,02040572 0,04274422 ! cartilage condensation GO:0001502 18 12 0,000 0,02040572 0,04270533 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02040572 0,0426665 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02040572 0,04262775 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02040572 0,04258907 ! heart looping GO:0001947 15 12 0,000 0,02040572 0,04255046 ! palate development GO:0060021 15 12 0,000 0,02040572 0,04251191 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02040572 0,04247344 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02040572 0,04243504 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02040572 0,0423967 ! arginine metabolic process GO:0006525 13 12 0,000 0,02040572 0,04235844 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02040572 0,04232025 ! methionine metabolic process GO:0006555 13 12 0,000 0,02040572 0,04228212 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02040572 0,04224406 ! Golgi organization GO:0007030 18 12 0,000 0,02040572 0,04220607 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02040572 0,04216815 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02040572 0,0421303 ! monoamine transport GO:0015844 13 12 0,000 0,02040572 0,04209251 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02040572 0,0420548 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02040572 0,04201715 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02040572 0,04197956 ! L-amino acid transport GO:0015807 20 12 0,000 0,02040572 0,04194205 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02040572 0,0419046 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02040572 0,04186722 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02040572 0,0418299 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02040572 0,04179266 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02040572 0,04175547 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02040572 0,04171836 ! cerebellum development GO:0021549 13 12 0,000 0,02040572 0,04168131 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02040572 0,04164432 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02040572 0,0416074 ! histone acetylation GO:0016573 23 12 0,000 0,02040572 0,04157055 ! histone methylation GO:0016571 15 12 0,000 0,02040572 0,04153376 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02040572 0,04149704 ! gland morphogenesis GO:0022612 23 12 0,000 0,02040572 0,04146038 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02040572 0,04142379 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02040572 0,04138726 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02040572 0,04135079 ! response to gamma radiation GO:0010332 20 12 0,000 0,02040572 0,04131439 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02040572 0,04127806 ! intestinal absorption GO:0050892 19 12 0,000 0,02040572 0,04124179 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02040572 0,04120558 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02040572 0,04116943 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02040572 0,04113335 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02040572 0,04109733 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02040572 0,04106138 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02040572 0,04102548 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02040572 0,04098965 ! microspike assembly GO:0030035 23 12 0,000 0,02040572 0,04095389 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02040572 0,04091818 ! response to cold GO:0009409 14 12 0,000 0,02040572 0,04088254 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02208791 0,04421426 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02208791 0,04417581 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02208791 0,04413743 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02208791 0,04409912 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02208791 0,04406087 ! water transport GO:0006833 17 13 0,000 0,02208791 0,04402269 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02208791 0,04398458 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02208791 0,04394653 ! lipid localization GO:0010876 24 13 0,000 0,02208791 0,04390854 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02208791 0,04387063 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02208791 0,04383277 ! organelle fusion GO:0048284 28 13 0,000 0,02208791 0,04379499 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02208791 0,04375727 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02208791 0,04371961 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02208791 0,04368202 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02208791 0,04364449 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02208791 0,04360703 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02208791 0,04356963 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,02208791 0,04353229 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02208791 0,04349502 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02208791 0,04345781 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02208791 0,04342067 ! NAD metabolic process GO:0019674 21 13 0,000 0,02208791 0,04338359 ! exocrine system development GO:0035272 27 13 0,000 0,02208791 0,04334657 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02208791 0,04330962 ! bone mineralization GO:0030282 15 13 0,000 0,02208791 0,04327273 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02208791 0,0432359 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02208791 0,04319914 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02208791 0,04316243 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02208791 0,04312579 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02208791 0,04308922 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02208791 0,0430527 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02208791 0,04301624 ! genitalia development GO:0048806 15 13 0,000 0,02208791 0,04297985 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02208791 0,04294352 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02208791 0,04290725 ! cellular pigmentation GO:0033059 24 13 0,000 0,02208791 0,04287104 ! tissue regeneration GO:0042246 21 13 0,000 0,02208791 0,04283489 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02208791 0,04279881 ! cofactor transport GO:0051181 19 13 0,000 0,02208791 0,04276278 ! NADP metabolic process GO:0006739 18 13 0,000 0,02208791 0,04272682 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02208791 0,04269091 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02208791 0,04265507 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02208791 0,04261928 ! gas transport GO:0015669 18 13 0,000 0,02208791 0,04258356 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02208791 0,04254789 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02208791 0,04251229 ! regulation of axon extension GO:0030516 23 13 0,000 0,02208791 0,04247674 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02208791 0,04244126 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02208791 0,04240583 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02208791 0,04237046 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02208791 0,04233515 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02208791 0,0422999 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02208791 0,04226471 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0237673 0,0454404 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0237673 0,04540265 ! superoxide anion generation GO:0042554 18 14 0,000 0,0237673 0,04536498 ! neuron maturation GO:0042551 21 14 0,000 0,0237673 0,04532736 ! regulation of S phase GO:0033261 18 14 0,000 0,0237673 0,04528981 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0237673 0,04525231 ! myotube differentiation GO:0014902 21 14 0,000 0,0237673 0,04521488 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,0237673 0,04517752 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0237673 0,04514021 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0237673 0,04510297 ! inositol metabolic process GO:0006020 20 14 0,000 0,0237673 0,04506578 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0237673 0,04502866 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0237673 0,0449916 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0237673 0,0449546 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0237673 0,04491766 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0237673 0,04488078 ! response to cAMP GO:0051591 19 14 0,000 0,0237673 0,04484397 ! limbic system development GO:0021761 25 14 0,000 0,0237673 0,04480721 ! startle response GO:0001964 21 14 0,000 0,0237673 0,04477051 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0237673 0,04473387 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0237673 0,0446973 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0237673 0,04466078 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0237673 0,04462432 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0237673 0,04458792 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0237673 0,04455159 ! glycine metabolic process GO:0006544 22 14 0,000 0,0237673 0,04451531 ! pituitary gland development GO:0021983 23 14 0,000 0,0237673 0,04447908 ! cellular response to starvation GO:0009267 21 14 0,000 0,0237673 0,04444292 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0237673 0,04440682 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0237673 0,04437078 ! regulation of heart rate GO:0002027 23 14 0,000 0,0237673 0,04433479 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0237673 0,04429886 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0237673 0,04426299 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0237673 0,04422718 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0237673 0,04419143 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0237673 0,04415573 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0237673 0,04412009 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0237673 0,04408451 ! axon cargo transport GO:0008088 27 14 0,000 0,0237673 0,04404899 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0237673 0,04401352 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0237673 0,04397811 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0237673 0,04394276 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0237673 0,04390747 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0237673 0,04387223 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0237673 0,04383705 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0237673 0,04380192 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0237673 0,04376685 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0237673 0,04373184 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0237673 0,04369688 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0237673 0,04366198 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0237673 0,04362713 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0237673 0,04359234 ! muscle maintenance GO:0046716 19 14 0,000 0,0237673 0,04355761 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0237673 0,04352293 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0237673 0,0434883 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0237673 0,04345373 ! cell killing GO:0001906 20 14 0,000 0,0237673 0,04341922 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0237673 0,04338476 ! cilium assembly GO:0042384 20 14 0,000 0,0237673 0,04335035 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0237673 0,043316 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02544391 0,04633491 ! metencephalon development GO:0022037 19 15 0,000 0,02544391 0,04629825 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02544391 0,04626165 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02544391 0,04622511 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02544391 0,04618863 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02544391 0,0461522 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02544391 0,04611583 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02544391 0,04607952 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02544391 0,04604327 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02544391 0,04600707 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02544391 0,04597093 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02544391 0,04593485 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02544391 0,04589882 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02544391 0,04586285 ! adult walking behavior GO:0007628 25 15 0,000 0,02544391 0,04582693 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02544391 0,04579107 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02544391 0,04575527 ! myoblast differentiation GO:0045445 27 15 0,000 0,02544391 0,04571953 ! centrosome cycle GO:0007098 16 15 0,000 0,02544391 0,04568383 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02544391 0,0456482 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02544391 0,04561262 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02544391 0,0455771 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02544391 0,04554163 ! cerebral cortex development GO:0021987 29 15 0,000 0,02544391 0,04550622 ! response to osmotic stress GO:0006970 22 15 0,000 0,02544391 0,04547086 ! vesicle coating GO:0006901 25 15 0,000 0,02544391 0,04543555 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02544391 0,0454003 ! DNA integration GO:0015074 22 15 0,000 0,02544391 0,04536511 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02544391 0,04532997 ! peptide secretion GO:0002790 27 15 0,000 0,02544391 0,04529489 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02544391 0,04525986 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02544391 0,04522488 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02544391 0,04518996 ! neuron recognition GO:0008038 22 15 0,000 0,02544391 0,04515509 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02544391 0,04512027 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02544391 0,04508551 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02544391 0,0450508 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02544391 0,04501615 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02544391 0,04498155 ! biomineral formation GO:0031214 18 15 0,000 0,02544391 0,044947 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02544391 0,0449125 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02544391 0,04487806 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02544391 0,04484367 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02544391 0,04480934 ! organic cation transport GO:0015695 19 15 0,000 0,02544391 0,04477505 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02544391 0,04474082 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02544391 0,04470664 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02544391 0,04467251 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,02544391 0,04463844 ! peptide hormone processing GO:0016486 19 15 0,000 0,02544391 0,04460442 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02544391 0,04457044 ! protein secretion GO:0009306 27 16 0,000 0,02711773 0,04746635 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02711773 0,04743026 ! hormone secretion GO:0046879 25 16 0,000 0,02711773 0,04739422 ! bone remodeling GO:0046849 24 16 0,000 0,02711773 0,04735823 ! endothelial cell migration GO:0043542 22 16 0,000 0,02711773 0,0473223 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02711773 0,04728642 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02711773 0,0472506 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02711773 0,04721483 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02711773 0,04717911 ! glial cell development GO:0021782 24 16 0,000 0,02711773 0,04714345 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02711773 0,04710785 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02711773 0,04707229 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02711773 0,04703679 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02711773 0,04700135 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02711773 0,04696595 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02711773 0,04693062 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02711773 0,04689533 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02711773 0,0468601 ! protein export from nucleus GO:0006611 24 16 0,000 0,02711773 0,04682492 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02711773 0,04678979 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02711773 0,04675471 ! DNA replication initiation GO:0006270 25 16 0,000 0,02711773 0,04671969 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02711773 0,04668472 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02711773 0,0466498 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02711773 0,04661494 ! diencephalon development GO:0021536 25 16 0,000 0,02711773 0,04658013 ! oogenesis GO:0048477 23 16 0,000 0,02711773 0,04654536 ! neural crest cell migration GO:0001755 24 16 0,000 0,02711773 0,04651065 ! G1 phase GO:0051318 27 16 0,000 0,02711773 0,046476 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02711773 0,04644139 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02711773 0,04640684 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02711773 0,04637233 ! steroid catabolic process GO:0006706 22 16 0,000 0,02711773 0,04633788 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02711773 0,04630348 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02711773 0,04626913 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02711773 0,04623483 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02711773 0,04620058 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02711773 0,04616639 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02711773 0,04613224 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02711773 0,04609814 ! nerve development GO:0021675 18 16 0,000 0,02711773 0,0460641 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02711773 0,0460301 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02711773 0,04599616 ! negative regulation of translation GO:0017148 22 16 0,000 0,02711773 0,04596226 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02878878 0,04875861 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02878878 0,04872273 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02878878 0,0486869 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02878878 0,04865113 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02878878 0,04861541 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02878878 0,04857974 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02878878 0,04854413 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02878878 0,04850856 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02878878 0,04847305 ! signal complex assembly GO:0007172 29 17 0,000 0,02878878 0,04843759 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02878878 0,04840219 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02878878 0,04836683 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02878878 0,04833153 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02878878 0,04829627 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02878878 0,04826107 ! memory GO:0007613 25 17 0,000 0,02878878 0,04822592 ! keratinization GO:0031424 17 17 0,000 0,02878878 0,04819082 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02878878 0,04815578 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02878878 0,04812078 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02878878 0,04808583 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02878878 0,04805094 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02878878 0,04801609 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02878878 0,0479813 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02878878 0,04794655 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02878878 0,04791186 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02878878 0,04787722 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02878878 0,04784262 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02878878 0,04780808 ! heme metabolic process GO:0042168 27 17 0,000 0,02878878 0,04777359 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02878878 0,04773914 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02878878 0,04770475 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02878878 0,0476704 ! body fluid secretion GO:0007589 27 17 0,000 0,02878878 0,04763611 ! stem cell differentiation GO:0048863 36 17 0,000 0,02878878 0,04760186 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02878878 0,04756767 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02878878 0,04753352 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02878878 0,04749942 ! sensory perception of pain GO:0019233 23 17 0,000 0,02878878 0,04746537 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02878878 0,04743137 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02878878 0,04739742 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02878878 0,04736351 ! synaptogenesis GO:0007416 24 17 0,000 0,02878878 0,04732966 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02878878 0,04729585 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02878878 0,04726209 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02878878 0,04722838 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02878878 0,04719472 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02878878 0,0471611 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02878878 0,04712754 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02878878 0,04709402 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02878878 0,04706055 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02878878 0,04702712 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03045705 0,04971697 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03045705 0,04968171 ! positive regulation of translation GO:0045727 28 18 0,000 0,03045705 0,0496465 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03045705 0,04961134 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03045705 0,04957623 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03045705 0,04954117 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03045705 0,04950616 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03045705 0,04947119 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03045705 0,04943628 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03045705 0,04940142 ! axis specification GO:0009798 26 18 0,000 0,03045705 0,0493666 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03045705 0,04933184 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03045705 0,04929712 ! pancreas development GO:0031016 26 18 0,000 0,03045705 0,04926246 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03045705 0,04922784 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03045705 0,04919327 ! response to retinoic acid GO:0032526 25 18 0,000 0,03045705 0,04915875 ! pigmentation during development GO:0048066 31 18 0,000 0,03045705 0,04912427 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03045705 0,04908985 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03045705 0,04905547 ! fucose metabolic process GO:0006004 26 18 0,000 0,03045705 0,04902114 ! response to fungus GO:0009620 19 18 0,000 0,03045705 0,04898686 ! peptide cross-linking GO:0018149 31 18 0,000 0,03045705 0,04895263 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03045705 0,04891844 ! heart process GO:0003015 27 18 0,000 0,03045705 0,04888431 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03045705 0,04885022 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03045705 0,04881618 ! somitogenesis GO:0001756 24 18 0,000 0,03045705 0,04878218 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03045705 0,04874823 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03045705 0,04871433 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03045705 0,04868048 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03045705 0,04864667 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03045705 0,04861292 ! vitamin transport GO:0051180 24 18 0,000 0,03045705 0,0485792 ! hormone transport GO:0009914 27 18 0,000 0,03045705 0,04854554 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03045705 0,04851192 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03045705 0,04847835 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03045705 0,04844482 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03045705 0,04841134 ! cell-cell recognition GO:0009988 20 18 0,000 0,03045705 0,04837791 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03045705 0,04834452 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03045705 0,04831118 ! regulation of glucose import GO:0046324 21 18 0,000 0,03045705 0,04827789 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03045705 0,04824464 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03045705 0,04821143 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03045705 0,04817827 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03045705 0,04814516 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03212255 0,05074304 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03212255 0,05070821 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03212255 0,05067343 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03212255 0,0506387 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03212255 0,05060401 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03212255 0,05056938 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03212255 0,05053479 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03212255 0,05050025 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03212255 0,05046575 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03212255 0,0504313 ! regeneration GO:0031099 32 19 0,000 0,03212255 0,0503969 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03212255 0,05036255 ! response to alkaloid GO:0043279 32 19 0,000 0,03212255 0,05032824 ! sensory perception of taste GO:0050909 23 19 0,000 0,03212255 0,05029398 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03212255 0,05025977 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03212255 0,0502256 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03212255 0,05019148 ! peroxisome organization GO:0007031 29 19 0,000 0,03212255 0,05015741 ! digestive system process GO:0022600 30 19 0,000 0,03212255 0,05012338 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03212255 0,0500894 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03212255 0,05005546 ! response to vitamin A GO:0033189 26 19 0,000 0,03212255 0,05002157 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03212255 0,04998773 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03212255 0,04995393 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03212255 0,04992018 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03212255 0,04988647 ! response to starvation GO:0042594 30 19 0,000 0,03212255 0,04985281 ! sex determination GO:0007530 29 19 0,000 0,03212255 0,04981919 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03212255 0,04978562 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03212255 0,0497521 ! cytolysis GO:0019835 20 19 0,000 0,03212255 0,04971861 ! renal system process GO:0003014 35 19 0,000 0,03212255 0,04968518 ! vasodilation GO:0042311 33 19 0,000 0,03212255 0,04965179 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03212255 0,04961844 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03212255 0,04958514 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03212255 0,04955189 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03212255 0,04951867 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03212255 0,04948551 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03212255 0,04945238 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03212255 0,04941931 ! sarcomere organization GO:0045214 23 19 0,000 0,03212255 0,04938627 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03212255 0,04935328 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03212255 0,04932033 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03212255 0,04928743 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03212255 0,04925457 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03212255 0,04922176 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03212255 0,04918899 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03212255 0,04915626 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03212255 0,04912358 ! protein stabilization GO:0050821 26 19 0,000 0,03212255 0,04909094 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03378528 0,05159771 ! iron ion transport GO:0006826 37 20 0,000 0,03378528 0,05156347 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03378528 0,05152928 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03378528 0,05149513 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03378528 0,05146103 ! response to vitamin GO:0033273 29 20 0,000 0,03378528 0,05142697 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03378528 0,05139296 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03378528 0,05135899 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03378528 0,05132507 ! spinal cord development GO:0021510 31 20 0,000 0,03378528 0,05129119 ! response to ethanol GO:0045471 37 20 0,000 0,03378528 0,05125735 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03378528 0,05122357 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03378528 0,05118982 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03378528 0,05115612 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03378528 0,05112247 ! chromosome condensation GO:0030261 31 20 0,000 0,03378528 0,05108886 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03378528 0,05105529 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03378528 0,05102177 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03378528 0,05098829 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03378528 0,05095485 ! pallium development GO:0021543 38 20 0,000 0,03378528 0,05092146 ! DNA modification GO:0006304 28 20 0,000 0,03378528 0,05088811 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03378528 0,05085481 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03378528 0,05082155 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03378528 0,05078833 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03378528 0,05075516 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03378528 0,05072203 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03378528 0,05068894 ! collagen catabolic process GO:0030574 25 20 0,000 0,03378528 0,0506559 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03378528 0,0506229 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03378528 0,05058994 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03378528 0,05055703 ! actin filament-based movement GO:0030048 34 20 0,000 0,03378528 0,05052415 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03544525 0,05297212 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03544525 0,05293772 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03544525 0,05290337 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03544525 0,05286906 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03544525 0,05283479 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03544525 0,05280057 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03544525 0,0527664 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03544525 0,05273227 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03544525 0,05269818 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03544525 0,05266414 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03544525 0,05263014 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03544525 0,05259618 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03544525 0,05256227 ! vesicle docking GO:0048278 27 21 0,000 0,03544525 0,05252841 ! phototransduction GO:0007602 25 21 0,000 0,03544525 0,05249458 ! dendrite development GO:0016358 35 21 0,000 0,03544525 0,0524608 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03544525 0,05242707 ! ovarian follicle development GO:0001541 30 21 0,000 0,03544525 0,05239337 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03544525 0,05235972 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03544525 0,05232611 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03544525 0,05229255 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03544525 0,05225903 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03544525 0,05222555 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03544525 0,05219212 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03544525 0,05215872 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03544525 0,05212537 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03544525 0,05209207 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03544525 0,0520588 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03544525 0,05202558 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03544525 0,0519924 ! fatty acid transport GO:0015908 30 21 0,000 0,03544525 0,05195926 ! immunoglobulin production GO:0002377 33 21 0,000 0,03544525 0,05192617 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03544525 0,05189312 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03544525 0,05186011 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03544525 0,05182714 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03544525 0,05179421 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,03544525 0,05176132 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03544525 0,05172848 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03544525 0,05169568 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03544525 0,05166292 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03544525 0,0516302 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03544525 0,05159752 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03544525 0,05156489 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03544525 0,05153229 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03544525 0,05149974 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03544525 0,05146723 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03544525 0,05143475 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03710247 0,0538056 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03710247 0,0537717 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03710247 0,05373784 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03710247 0,05370402 ! viral genome replication GO:0019079 29 22 0,000 0,03710247 0,05367024 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03710247 0,05363651 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03710247 0,05360282 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03710247 0,05356917 ! molting cycle process GO:0022404 40 22 0,000 0,03710247 0,05353556 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03710247 0,053502 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03710247 0,05346847 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03710247 0,05343499 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03710247 0,05340155 ! vasculogenesis GO:0001570 33 22 0,000 0,03710247 0,05336816 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03710247 0,0533348 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03710247 0,05330149 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03710247 0,05326822 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03710247 0,05323499 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03710247 0,0532018 ! lysosome organization GO:0007040 37 22 0,000 0,03710247 0,05316865 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03710247 0,05313554 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03710247 0,05310248 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03710247 0,05306945 ! regulation of behavior GO:0050795 38 22 0,000 0,03710247 0,05303647 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03710247 0,05300353 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03710247 0,05297063 ! membrane depolarization GO:0051899 35 22 0,000 0,03710247 0,05293777 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03710247 0,05290495 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03710247 0,05287217 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03710247 0,05283943 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03710247 0,05280673 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03710247 0,05277408 ! blastocyst development GO:0001824 37 22 0,000 0,03710247 0,05274146 ! neural tube closure GO:0001843 33 22 0,000 0,03710247 0,05270888 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03710247 0,05267635 ! protein tetramerization GO:0051262 39 22 0,000 0,03710247 0,05264385 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03875693 0,05495743 ! neuron fate commitment GO:0048663 32 23 0,000 0,03875693 0,05492357 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03875693 0,05488975 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03875693 0,05485597 ! myelination GO:0042552 35 23 0,000 0,03875693 0,05482223 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03875693 0,05478854 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03875693 0,05475488 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03875693 0,05472127 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03875693 0,0546877 ! vesicle targeting GO:0006903 32 23 0,000 0,03875693 0,05465417 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03875693 0,05462068 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03875693 0,05458723 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03875693 0,05455382 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03875693 0,05452046 ! interaction with host GO:0051701 37 23 0,000 0,03875693 0,05448713 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03875693 0,05445385 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03875693 0,0544206 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03875693 0,0543874 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03875693 0,05435424 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,03875693 0,05432111 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03875693 0,05428803 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03875693 0,05425499 ! cell fate determination GO:0001709 45 23 0,000 0,03875693 0,05422199 ! pentose metabolic process GO:0019321 31 23 0,000 0,03875693 0,05418903 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03875693 0,0541561 ! spermatid development GO:0007286 33 23 0,000 0,03875693 0,05412322 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03875693 0,05409038 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03875693 0,05405758 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03875693 0,05402482 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03875693 0,05399209 ! telomere organization GO:0032200 32 23 0,000 0,03875693 0,05395941 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03875693 0,05392677 ! regulation of amine transport GO:0051952 38 23 0,000 0,03875693 0,05389416 ! liver development GO:0001889 40 23 0,000 0,03875693 0,0538616 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04040865 0,05612312 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04040865 0,05608925 ! initiation of viral infection GO:0019059 42 24 0,000 0,04040865 0,05605542 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04040865 0,05602163 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04040865 0,05598789 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04040865 0,05595418 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04040865 0,05592051 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04040865 0,05588689 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04040865 0,0558533 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04040865 0,05581975 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04040865 0,05578625 ! vacuole organization GO:0007033 39 24 0,000 0,04040865 0,05575278 ! receptor metabolic process GO:0043112 37 24 0,000 0,04040865 0,05571936 ! neural crest cell development GO:0014032 39 24 0,000 0,04040865 0,05568597 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04040865 0,05565263 ! primary neural tube formation GO:0014020 35 24 0,000 0,04040865 0,05561932 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04040865 0,05558606 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04040865 0,05555283 ! base-excision repair GO:0006284 31 24 0,000 0,04040865 0,05551965 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04040865 0,0554865 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04040865 0,0554534 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04040865 0,05542033 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04040865 0,0553873 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04040865 0,05535431 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04040865 0,05532136 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04040865 0,05528845 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04205762 0,05751042 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04205762 0,05747625 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04205762 0,05744212 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04205762 0,05740803 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04205762 0,05737398 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04205762 0,05733997 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,04205762 0,057306 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04205762 0,05727207 ! peptide transport GO:0015833 43 25 0,000 0,04205762 0,05723818 ! male gonad development GO:0008584 33 25 0,000 0,04205762 0,05720433 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04205762 0,05717052 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04205762 0,05713675 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04205762 0,05710303 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04205762 0,05706934 ! phospholipid transport GO:0015914 35 25 0,000 0,04205762 0,05703569 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04205762 0,05700208 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04205762 0,05696851 ! detection of light stimulus GO:0009583 30 25 0,000 0,04205762 0,05693498 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04205762 0,05690149 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04205762 0,05686803 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04205762 0,05683462 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04205762 0,05680125 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04370385 0,05898994 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04370385 0,05895534 ! translational initiation GO:0006413 43 26 0,000 0,04370385 0,05892079 ! regulation of pH GO:0006885 36 26 0,000 0,04370385 0,05888627 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04370385 0,05885179 ! circadian rhythm GO:0007623 42 26 0,000 0,04370385 0,05881735 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04370385 0,05878296 ! post-embryonic development GO:0009791 42 26 0,000 0,04370385 0,0587486 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04370385 0,05871429 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04370385 0,05868001 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04370385 0,05864578 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04370385 0,05861158 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04370385 0,05857742 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04370385 0,05854331 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04370385 0,05850923 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04370385 0,05847519 ! regulation of coagulation GO:0050818 39 26 0,000 0,04370385 0,0584412 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04534735 0,06060366 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04534735 0,06056847 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04534735 0,06053332 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04534735 0,0604982 ! membrane docking GO:0022406 39 27 0,000 0,04534735 0,06046313 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04534735 0,0604281 ! catechol metabolic process GO:0009712 43 27 0,000 0,04534735 0,06039311 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04534735 0,06035816 ! acute-phase response GO:0006953 42 27 0,000 0,04534735 0,06032325 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04534735 0,06028838 ! myofibril assembly GO:0030239 36 27 0,000 0,04534735 0,06025355 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04534735 0,06021877 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04534735 0,06018402 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04534735 0,06014931 ! natural killer cell activation GO:0030101 35 27 0,000 0,04534735 0,06011464 ! lipid oxidation GO:0034440 38 27 0,000 0,04534735 0,06008001 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04534735 0,06004542 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04534735 0,06001088 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04534735 0,05997637 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04534735 0,0599419 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04534735 0,05990747 ! gene silencing GO:0016458 41 27 0,000 0,04534735 0,05987308 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04698812 0,06200382 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04698812 0,06196827 ! phenol metabolic process GO:0018958 44 28 0,000 0,04698812 0,06193276 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04698812 0,06189729 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04698812 0,06186186 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04698812 0,06182647 ! cell junction assembly GO:0034329 56 28 0,000 0,04698812 0,06179112 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04698812 0,06175581 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04698812 0,06172054 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04698812 0,06168531 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04698812 0,06165012 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04698812 0,06161497 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04698812 0,06157987 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04698812 0,0615448 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04698812 0,06150977 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04698812 0,06147478 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04698812 0,06143983 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04698812 0,06140492 ! mesoderm formation GO:0001707 46 28 0,000 0,04698812 0,06137005 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04698812 0,06133522 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04698812 0,06130043 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04698812 0,06126568 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04698812 0,06123097 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04698812 0,0611963 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04698812 0,06116167 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04698812 0,06112707 ! neural tube formation GO:0001841 41 28 0,000 0,04698812 0,06109252 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04698812 0,061058 ! placenta development GO:0001890 37 28 0,000 0,04698812 0,06102353 ! regulation of B cell activation GO:0050864 42 28 0,000 0,04698812 0,06098909 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04862616 0,06307962 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04862616 0,06304406 ! ovulation cycle process GO:0022602 41 29 0,000 0,04862616 0,06300854 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04862616 0,06297306 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04862616 0,06293762 ! mismatch repair GO:0006298 34 29 0,000 0,04862616 0,06290223 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04862616 0,06286687 ! muscle cell development GO:0055001 38 29 0,000 0,04862616 0,06283155 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04862616 0,06279627 ! telencephalon development GO:0021537 52 29 0,000 0,04862616 0,06276103 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04862616 0,06272583 ! tissue homeostasis GO:0001894 42 29 0,000 0,04862616 0,06269067 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05026147 0,06476268 ! collagen metabolic process GO:0032963 40 30 0,000 0,05026147 0,06472642 ! organic anion transport GO:0015711 51 30 0,000 0,05026147 0,0646902 ! cholesterol transport GO:0030301 46 30 0,000 0,05026147 0,06465402 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05026147 0,06461788 ! spliceosome assembly GO:0000245 49 30 0,000 0,05026147 0,06458178 ! spindle organization GO:0007051 37 30 0,000 0,05026147 0,06454572 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05026147 0,0645097 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05026147 0,06447373 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05026147 0,06443779 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05026147 0,06440189 ! ovulation cycle GO:0042698 43 30 0,000 0,05026147 0,06436603 ! hindbrain development GO:0030902 45 30 0,000 0,05026147 0,06433021 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05026147 0,06429443 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05026147 0,06425869 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05026147 0,064223 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05026147 0,06418734 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05026147 0,06415172 ! response to heat GO:0009408 41 30 0,000 0,05026147 0,06411613 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05026147 0,06408059 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05026147 0,06404509 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05189408 0,0660888 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05189408 0,06605223 ! mammary gland development GO:0030879 57 31 0,000 0,05189408 0,06601569 ! glial cell differentiation GO:0010001 55 31 0,000 0,05189408 0,0659792 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05189408 0,06594275 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05189408 0,06590634 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05189408 0,06586996 ! odontogenesis GO:0042476 50 31 0,000 0,05189408 0,06583363 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05189408 0,06579734 ! segmentation GO:0035282 41 31 0,000 0,05189408 0,06576109 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05189408 0,06572488 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05189408 0,0656887 ! metanephros development GO:0001656 58 31 0,000 0,05189408 0,06565257 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05189408 0,06561648 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05189408 0,06558043 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05189408 0,06554441 ! cell fate specification GO:0001708 37 31 0,000 0,05189408 0,06550844 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05189408 0,0654725 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05189408 0,06543661 ! RNA modification GO:0009451 40 31 0,000 0,05189408 0,06540075 ! regulation of muscle development GO:0048634 48 32 0,000 0,05352396 0,06741792 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05352396 0,06738102 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05352396 0,06734416 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,05352396 0,06730734 ! meiosis I GO:0007127 52 32 0,000 0,05352396 0,06727056 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05352396 0,06723382 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05352396 0,06719712 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05352396 0,06716046 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05352396 0,06712384 ! regulation of protein stability GO:0031647 48 32 0,000 0,05352396 0,06708726 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05352396 0,06705072 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05352396 0,06701422 ! cytokine production GO:0001816 44 32 0,000 0,05352396 0,06697776 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05352396 0,06694134 ! vesicle localization GO:0051648 47 32 0,000 0,05352396 0,06690495 ! RNA export from nucleus GO:0006405 44 33 0,000 0,05515114 0,06890148 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05515114 0,06886408 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,05515114 0,06882671 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05515114 0,06878939 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05515114 0,0687521 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05515114 0,06871486 ! ear morphogenesis GO:0042471 42 33 0,000 0,05515114 0,06867766 ! actomyosin structure organization GO:0031032 43 33 0,000 0,05515114 0,06864049 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05515114 0,06860337 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05515114 0,06856629 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05515114 0,06852924 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,05515114 0,06849224 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05515114 0,06845528 ! female gonad development GO:0008585 49 33 0,000 0,05515114 0,06841835 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05515114 0,06838147 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05515114 0,06834463 ! lipid homeostasis GO:0055088 55 33 0,000 0,05515114 0,06830782 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05515114 0,06827106 ! regulation of proteolysis GO:0030162 50 33 0,000 0,05515114 0,06823434 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05515114 0,06819765 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05515114 0,068161 ! cytokinesis GO:0000910 52 33 0,000 0,05515114 0,0681244 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05515114 0,06808783 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05677562 0,07005575 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05677562 0,07001819 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05677562 0,06998067 ! feeding behavior GO:0007631 45 34 0,000 0,05677562 0,06994318 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05677562 0,06990574 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05677562 0,06986834 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05677562 0,06983097 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05677562 0,06979365 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05677562 0,06975637 ! neuron migration GO:0001764 46 34 0,000 0,05677562 0,06971913 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05677562 0,06968192 ! female gamete generation GO:0007292 43 34 0,000 0,05677562 0,06964476 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05677562 0,06960763 ! aerobic respiration GO:0009060 47 34 0,000 0,05677562 0,06957055 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05677562 0,0695335 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,05677562 0,0694965 ! embryonic organ development GO:0048568 45 34 0,000 0,05677562 0,06945953 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05677562 0,06942261 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05839739 0,0713677 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05839739 0,0713298 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05839739 0,07129193 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05839739 0,07125411 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05839739 0,07121633 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05839739 0,07117859 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05839739 0,07114089 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05839739 0,07110323 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05839739 0,07106561 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05839739 0,07102803 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05839739 0,07099049 ! pigment metabolic process GO:0042440 61 35 0,000 0,05839739 0,07095299 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,05839739 0,07091553 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,05839739 0,0708781 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06001647 0,07280479 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06001647 0,07276641 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06001647 0,07272808 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06001647 0,07268978 ! negative regulation of binding GO:0051100 58 36 0,000 0,06001647 0,07265152 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06001647 0,0726133 ! tissue remodeling GO:0048771 62 36 0,000 0,06001647 0,07257512 ! neural tube development GO:0021915 50 36 0,000 0,06001647 0,07253699 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06001647 0,07249889 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06001647 0,07246083 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06001647 0,07242282 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06001647 0,07238484 ! glucan metabolic process GO:0044042 49 36 0,000 0,06001647 0,0723469 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06163286 0,07425646 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06163286 0,07421758 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06163286 0,07417874 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06163286 0,07413995 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06163286 0,07410119 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06163286 0,07406248 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06163286 0,0740238 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06324656 0,07592228 ! gliogenesis GO:0042063 71 38 0,000 0,06324656 0,07588268 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06324656 0,07584311 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06324656 0,07580359 ! phagocytosis GO:0006909 60 38 0,000 0,06324656 0,07576411 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06324656 0,07572467 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06324656 0,07568527 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06324656 0,07564591 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06485758 0,07753245 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06485758 0,07749217 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06485758 0,07745194 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06485758 0,07741175 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06485758 0,07737159 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06485758 0,07733148 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06485758 0,07729142 ! male sex differentiation GO:0046661 53 39 0,000 0,06485758 0,07725139 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06485758 0,0772114 ! chromatin remodeling GO:0006338 68 39 0,000 0,06485758 0,07717146 ! JNK cascade GO:0007254 54 39 0,000 0,06485758 0,07713156 ! developmental growth GO:0048589 62 39 0,000 0,06485758 0,0770917 ! cell growth GO:0016049 61 39 0,000 0,06485758 0,07705188 ! synapse organization GO:0050808 55 39 0,000 0,06485758 0,0770121 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06646592 0,07888112 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06646592 0,07884044 ! regulation of tube size GO:0035150 60 40 0,000 0,06646592 0,0787998 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06646592 0,0787592 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06646592 0,07871865 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06646592 0,07867813 ! peptide metabolic process GO:0006518 56 40 0,000 0,06646592 0,07863766 ! inner ear development GO:0048839 57 40 0,000 0,06646592 0,07859723 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06646592 0,07855684 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06646592 0,0785165 ! double-strand break repair GO:0006302 67 40 0,000 0,06646592 0,07847619 ! B cell differentiation GO:0030183 62 40 0,000 0,06646592 0,07843592 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06646592 0,0783957 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06646592 0,07835552 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06646592 0,07831538 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06807159 0,08016623 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06807159 0,0801252 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06807159 0,08008422 ! glucose transport GO:0015758 52 41 0,000 0,06807159 0,08004328 ! endosome transport GO:0016197 71 41 0,000 0,06807159 0,08000237 ! striated muscle contraction GO:0006941 62 41 0,000 0,06807159 0,07996152 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06807159 0,0799207 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06807159 0,07987992 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06807159 0,07983919 ! biopolymer methylation GO:0043414 62 41 0,000 0,06807159 0,0797985 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06807159 0,07975784 ! mitochondrial transport GO:0006839 60 42 0,000 0,06967458 0,08159447 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,06967458 0,08155295 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06967458 0,08151146 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06967458 0,08147002 ! cellular component disassembly GO:0022411 64 42 0,000 0,06967458 0,08142863 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06967458 0,08138727 ! hexose transport GO:0008645 54 42 0,000 0,06967458 0,08134596 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06967458 0,08130469 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06967458 0,08126346 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06967458 0,08122227 ! excretion GO:0007588 63 42 0,000 0,06967458 0,08118112 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06967458 0,08114002 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06967458 0,08109896 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06967458 0,08105794 ! regulation of cell shape GO:0008360 78 42 0,000 0,06967458 0,08101696 ! positive regulation of binding GO:0051099 59 43 0,000 0,07127491 0,08283593 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,07127491 0,08279409 ! leukocyte migration GO:0050900 60 43 0,000 0,07127491 0,0827523 ! neuromuscular process GO:0050905 79 43 0,000 0,07127491 0,08271054 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07127491 0,08266883 ! tRNA processing GO:0008033 49 43 0,000 0,07127491 0,08262717 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07127491 0,08258554 ! response to insulin stimulus GO:0032868 63 43 0,000 0,07127491 0,08254396 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,07127491 0,08250241 ! methylation GO:0032259 64 43 0,000 0,07127491 0,08246091 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07287258 0,08426694 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07287258 0,08422459 ! glycolysis GO:0006096 53 44 0,000 0,07287258 0,08418229 ! regulation of action potential GO:0001508 71 44 0,000 0,07287258 0,08414003 ! regulation of ion transport GO:0043269 57 44 0,000 0,07287258 0,08409781 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07287258 0,08405564 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07287258 0,0840135 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07287258 0,08397141 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07287258 0,08392936 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07287258 0,08388736 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07287258 0,08384539 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,07287258 0,08380347 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07446759 0,08559494 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07446759 0,08555218 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,07446759 0,08550947 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07446759 0,0854668 ! cell recognition GO:0008037 58 45 0,000 0,07446759 0,08542417 ! cell maturation GO:0048469 60 45 0,000 0,07446759 0,08538159 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07605995 0,08716387 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07605995 0,08712046 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07605995 0,0870771 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07605995 0,08703378 ! regulation of ossification GO:0030278 71 46 0,000 0,07605995 0,0869905 ! histone modification GO:0016570 68 46 0,000 0,07605995 0,08694726 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07605995 0,08690407 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07764966 0,08867638 ! viral infectious cycle GO:0019058 71 47 0,000 0,07764966 0,08863237 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07764966 0,08858841 ! endocrine system development GO:0035270 83 47 0,000 0,07764966 0,08854449 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07764966 0,08850061 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07764966 0,08845677 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07764966 0,08841298 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07764966 0,08836924 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07764966 0,08832553 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,07764966 0,08828187 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07764966 0,08823825 ! chloride transport GO:0006821 67 48 0,000 0,07923673 0,08999727 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07923673 0,08995285 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07923673 0,08990848 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07923673 0,08986414 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07923673 0,08981985 ! gastrulation GO:0007369 73 48 0,000 0,07923673 0,08977561 ! heart morphogenesis GO:0003007 65 48 0,000 0,07923673 0,0897314 ! regulation of DNA replication GO:0006275 75 48 0,000 0,07923673 0,08968724 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07923673 0,08964313 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07923673 0,08959906 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07923673 0,08955503 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07923673 0,08951104 ! nuclear export GO:0051168 69 48 0,000 0,07923673 0,0894671 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07923673 0,0894232 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07923673 0,08937934 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08082116 0,09112189 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08082116 0,09107725 ! sensory perception of smell GO:0007608 61 49 0,000 0,08082116 0,09103265 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08082116 0,09098809 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08082116 0,09094357 ! RNA elongation GO:0006354 62 49 0,000 0,08082116 0,0908991 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08082116 0,09085467 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08082116 0,09081029 ! germ cell development GO:0007281 68 49 0,000 0,08082116 0,09076595 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08082116 0,09072165 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08082116 0,0906774 ! cartilage development GO:0051216 70 49 0,000 0,08082116 0,09063319 ! maintenance of location GO:0051235 84 49 0,000 0,08082116 0,09058902 ! regulation of actin filament length GO:0030832 72 50 0,000 0,08240295 0,09231699 ! ear development GO:0043583 72 50 0,000 0,08240295 0,09227205 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,08240295 0,09222714 ! membrane fusion GO:0006944 80 50 0,000 0,08240295 0,09218229 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,08240295 0,09213747 ! lipid modification GO:0030258 73 50 0,000 0,08240295 0,0920927 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,08240295 0,09204798 ! proton transport GO:0015992 75 50 0,000 0,08240295 0,09200329 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,08240295 0,09195865 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08398211 0,09367548 ! hydrogen transport GO:0006818 77 51 0,000 0,08398211 0,09363008 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08398211 0,09358471 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,08398211 0,09353939 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08398211 0,09349412 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,08398211 0,09344889 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,08398211 0,0934037 ! adult behavior GO:0030534 80 51 0,000 0,08398211 0,09335855 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08398211 0,09331345 ! transition metal ion transport GO:0000041 74 52 0,000 0,08555864 0,09501925 ! regulation of cellular component size GO:0032535 74 52 0,000 0,08555864 0,09497339 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08555864 0,09492758 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,08555864 0,09488181 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08555864 0,09483608 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08555864 0,0947904 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,08713255 0,09648766 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08713255 0,09644123 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08713255 0,09639484 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08713255 0,09634849 ! kidney development GO:0001822 90 53 0,000 0,08713255 0,09630219 ! single fertilization GO:0007338 59 53 0,000 0,08713255 0,09625594 ! cell projection assembly GO:0030031 76 53 0,000 0,08713255 0,09620973 ! amino acid transport GO:0006865 84 54 0,000 0,08870384 0,09789771 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08870384 0,09785076 ! regulation of mitosis GO:0007088 84 54 0,000 0,08870384 0,09780385 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,08870384 0,09775699 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08870384 0,09771017 ! DNA catabolic process GO:0006308 67 54 0,000 0,08870384 0,0976634 ! detection of external stimulus GO:0009581 66 54 0,000 0,08870384 0,09761667 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08870384 0,09756998 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08870384 0,09752334 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08870384 0,09747675 ! exocytosis GO:0006887 74 55 0,000 0,09027252 0,09915319 ! mesoderm development GO:0007498 76 55 0,000 0,09027252 0,09910587 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09027252 0,09905858 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09027252 0,09901134 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,09183858 0,100681 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,09183858 0,10063303 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,09183858 0,10058511 ! carbohydrate transport GO:0008643 74 57 0,000 0,09340204 0,10224878 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09340204 0,10220014 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09340204 0,10215154 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09340204 0,10210299 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09340204 0,10205449 ! camera-type eye development GO:0043010 88 57 0,000 0,09340204 0,10200603 ! secondary metabolic process GO:0019748 84 57 0,000 0,09340204 0,10195762 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,09340204 0,10190925 ! developmental maturation GO:0021700 75 57 0,000 0,09340204 0,10186093 ! gonad development GO:0008406 79 57 0,000 0,09340204 0,10181265 ! viral reproductive process GO:0022415 87 58 0,000 0,0949629 0,10346503 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,0949629 0,10341604 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,0949629 0,10336709 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,0949629 0,1033182 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09652116 0,10496391 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09652116 0,1049143 ! lung development GO:0030324 94 59 0,000 0,09652116 0,10486474 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09652116 0,10481523 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09652116 0,10476577 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09807682 0,1064041 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,09807682 0,10635394 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09807682 0,10630382 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09807682 0,10625374 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,09807682 0,10620372 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09807682 0,10615374 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09807682 0,10610381 ! fertilization GO:0009566 68 60 0,000 0,09807682 0,10605392 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09807682 0,10600409 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,0996299 0,10763211 ! meiosis GO:0007126 96 61 0,000 0,0996299 0,10758158 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,0996299 0,1075311 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,0996299 0,10748066 ! urogenital system development GO:0001655 101 61 0,000 0,0996299 0,10743027 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,0996299 0,10737993 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,0996299 0,10732964 ! extracellular matrix organization GO:0030198 103 61 0,000 0,0996299 0,10727939 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,0996299 0,10722919 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,10118039 0,10884701 ! neurotransmitter transport GO:0006836 81 62 0,000 0,10118039 0,10879612 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,10118039 0,10874528 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,10118039 0,10869449 ! respiratory tube development GO:0030323 99 62 0,000 0,10118039 0,10864374 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,10118039 0,10859305 ! meiotic cell cycle GO:0051321 97 62 0,000 0,10118039 0,1085424 ! organelle localization GO:0051640 96 62 0,000 0,10118039 0,1084918 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,1027283 0,11010023 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,1027283 0,11004895 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,1027283 0,10999772 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,1027283 0,10994653 ! viral reproduction GO:0016032 92 63 0,000 0,1027283 0,10989539 ! regulation of lipase activity GO:0060191 109 63 0,000 0,1027283 0,1098443 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10427363 0,11144487 ! negative regulation of cell size GO:0045792 108 64 0,000 0,10427363 0,11139311 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10427363 0,11134139 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,10427363 0,11128973 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,10427363 0,11123811 ! hexose catabolic process GO:0019320 82 64 0,000 0,10427363 0,11118654 ! respiratory system development GO:0060541 100 64 0,000 0,10427363 0,11113501 ! adaptive immune response GO:0002250 94 64 0,000 0,10427363 0,11108354 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,10581639 0,11267486 ! appendage development GO:0048736 94 65 0,000 0,10581639 0,11262272 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,10581639 0,11257063 ! defense response to bacterium GO:0042742 73 65 0,000 0,10581639 0,11251859 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10581639 0,11246659 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10581639 0,11241464 ! activation of immune response GO:0002253 83 65 0,000 0,10581639 0,11236275 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,10735659 0,11394561 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10735659 0,11389306 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10735659 0,11384055 ! axon guidance GO:0007411 99 66 0,000 0,10735659 0,11378809 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10735659 0,11373567 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10735659 0,11368331 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10889421 0,11525848 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10889421 0,11520547 ! acute inflammatory response GO:0002526 92 68 0,000 0,11042928 0,11677579 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,11042928 0,11672212 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,11042928 0,11666851 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,11042928 0,11661494 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,11042928 0,11656142 ! rhythmic process GO:0048511 105 68 0,000 0,11042928 0,11650795 ! inorganic anion transport GO:0015698 93 68 0,000 0,11042928 0,11645453 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,11196179 0,11801655 ! response to drug GO:0042493 108 69 0,000 0,11196179 0,11796249 ! humoral immune response GO:0006959 86 70 0,000 0,11349174 0,11951969 ! amine transport GO:0015837 101 70 0,000 0,11349174 0,11946499 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,11349174 0,11941034 ! regulation of catabolic process GO:0009894 106 70 0,000 0,11349174 0,11935574 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,11501915 0,12090679 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,11501915 0,12085155 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11501915 0,12079637 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11501915 0,12074124 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11501915 0,12068616 ! response to hypoxia GO:0001666 132 72 0,000 0,11654402 0,12223039 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,11654402 0,12217468 ! negative regulation of transport GO:0051051 116 73 0,000 0,11806634 0,12371416 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11806634 0,12365783 ! tube morphogenesis GO:0035239 118 73 0,000 0,11806634 0,12360154 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11806634 0,12354531 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11806634 0,12348913 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,11958613 0,12502187 ! response to oxygen levels GO:0070482 137 74 0,000 0,11958613 0,12496506 ! digestion GO:0007586 97 74 0,000 0,11958613 0,12490831 ! protein import into nucleus GO:0006606 118 74 0,000 0,11958613 0,12485161 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,11958613 0,12479497 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,11958613 0,12473837 ! blood coagulation GO:0007596 116 75 0,000 0,12110339 0,12626373 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,12110339 0,12620652 ! nuclear import GO:0051170 121 75 0,000 0,12110339 0,12614936 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,12110339 0,12609226 ! amine biosynthetic process GO:0009309 97 76 0,000 0,12261812 0,12761162 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,12261812 0,1275539 ! regulation of protein transport GO:0051223 114 76 0,000 0,12261812 0,12749624 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,12413033 0,12901028 ! regulation of DNA binding GO:0051101 119 77 0,000 0,12413033 0,12895201 ! gland development GO:0048732 148 77 0,000 0,12413033 0,12889379 ! sex differentiation GO:0007548 105 77 0,000 0,12413033 0,12883563 ! protein ubiquitination GO:0016567 125 77 0,000 0,12413033 0,12877751 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,12413033 0,12871945 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12564001 0,13022624 ! cellular respiration GO:0045333 107 79 0,000 0,12714718 0,13172906 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,12714718 0,13166975 ! T cell activation GO:0042110 134 79 0,000 0,12714718 0,1316105 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,12714718 0,13155129 ! chromatin assembly GO:0031497 102 80 0,000 0,12865184 0,13304822 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,12865184 0,13298842 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12865184 0,13292868 ! forebrain development GO:0030900 131 80 0,000 0,12865184 0,13286899 ! hemostasis GO:0007599 125 81 0,000 0,13015399 0,13436005 ! mRNA transport GO:0051028 121 81 0,000 0,13015399 0,13429977 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,13015399 0,13423955 ! vitamin metabolic process GO:0006766 103 81 0,000 0,13015399 0,13417937 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,13015399 0,13411926 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,13165364 0,13560384 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,13315079 0,13708452 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,13315079 0,13702319 ! regulation of defense response GO:0031347 117 84 0,000 0,13464544 0,13849934 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,13464544 0,13843743 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13464544 0,13837557 ! sterol metabolic process GO:0016125 120 84 0,000 0,13464544 0,13831377 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,13613761 0,13978415 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13613761 0,13972177 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,13613761 0,13965945 ! transcription initiation GO:0006352 118 85 0,000 0,13613761 0,13959719 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13613761 0,13953498 ! regulation of protein localization GO:0032880 132 85 0,000 0,13613761 0,13947283 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13613761 0,13941073 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13613761 0,13934868 ! cell cycle arrest GO:0007050 150 86 0,000 0,13762728 0,14081083 ! nucleosome organization GO:0034728 114 87 0,000 0,13911447 0,14226914 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13911447 0,14220591 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13911447 0,14214273 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,13911447 0,14207961 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,13911447 0,14201655 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13911447 0,14195354 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,14059918 0,14340493 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,14059918 0,14334137 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,14059918 0,14327786 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,14059918 0,1432144 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,14059918 0,14315101 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,14208142 0,14459614 ! reproductive developmental process GO:0003006 127 89 0,000 0,14208142 0,14453218 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,14208142 0,14446829 ! regulation of T cell activation GO:0050863 128 89 0,000 0,14208142 0,14440445 ! leukocyte differentiation GO:0002521 143 90 0,000 0,14356119 0,14584396 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,14356119 0,14577957 ! hormone metabolic process GO:0042445 121 90 0,000 0,14356119 0,14571524 ! RNA localization GO:0006403 135 91 0,000 0,14503848 0,14714976 ! ATP metabolic process GO:0046034 137 91 0,000 0,14503848 0,14708488 ! response to virus GO:0009615 122 91 0,000 0,14503848 0,14702006 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14651332 0,14844962 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,14651332 0,14838425 ! cell fate commitment GO:0045165 141 92 0,000 0,14651332 0,14831894 ! positive regulation of immune response GO:0050778 121 92 0,000 0,14651332 0,14825369 ! DNA recombination GO:0006310 146 92 0,000 0,14651332 0,14818849 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14651332 0,14812336 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,14798569 0,14954618 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,14798569 0,1494805 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14798569 0,14941488 ! electron transport chain GO:0022900 123 94 0,000 0,14945561 0,15083278 ! response to oxidative stress GO:0006979 141 94 0,000 0,14945561 0,15076663 ! angiogenesis GO:0001525 149 95 0,000 0,15092308 0,15218022 ! carboxylic acid transport GO:0046942 147 95 0,000 0,15092308 0,15211353 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,1523881 0,15352284 ! in utero embryonic development GO:0001701 147 96 0,000 0,1523881 0,15345562 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,1523881 0,15338846 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,1523881 0,15332136 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,1523881 0,15325432 ! protein maturation GO:0051604 129 96 0,000 0,1523881 0,15318734 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,15385068 0,15459002 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,15676852 0,15745309 ! extracellular structure organization GO:0043062 156 99 0,000 0,15676852 0,15738437 ! protein import GO:0017038 156 99 0,000 0,15676852 0,1573157 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,15676852 0,15724709 ! regulation of translation GO:0006417 151 100 0,000 0,15822379 0,15863762 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,15822379 0,1585685 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15822379 0,15849944 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15822379 0,15843043 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15822379 0,15836149 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,15822379 0,15829261 ! protein localization in organelle GO:0033365 161 100 0,000 0,15822379 0,15822379