pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/7407-9-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 1,312E-08 3,158E-05 GO:0019405|alditol catabolic process, ! response to unfolded protein GO:0006986 131 85 4,000 4,147E-08 4,989E-05 ! response to protein stimulus GO:0051789 149 91 4,000 5,851E-08 4,692E-05 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 3,73E-07 2,244E-04 ! fructose metabolic process GO:0006000 25 16 2,000 7,288E-07 3,507E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 1,479E-06 5,931E-04 ! alditol metabolic process GO:0019400 38 24 2,000 2,618E-06 8,997E-04 ! sperm motility GO:0030317 31 25 2,000 2,972E-06 8,939E-04 ! osteoblast differentiation GO:0001649 60 25 2,000 2,972E-06 7,946E-04 ! hexose biosynthetic process GO:0019319 48 32 2,000 6,375E-06 1,534E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 9,149E-06 2,001E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 9,149E-06 1,834E-03 ! polyol metabolic process GO:0019751 66 41 2,000 1,361E-05 2,518E-03 ! alcohol biosynthetic process GO:0046165 59 42 2,000 1,464E-05 2,516E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 1,85E-05 2,968E-03 GO:0046530|photoreceptor cell differentiation, ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,337E-05 3,515E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 2,589E-05 3,664E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 2,589E-05 3,46E-03 ! amino acid activation GO:0043038 92 52 2,000 2,797E-05 3,542E-03 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,963E-05 3,564E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,449E-05 3,952E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 3,449E-05 3,772E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 1,000 3,449E-05 3,608E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 1,000 3,449E-05 3,458E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 3,689E-05 3,55E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 4,431E-05 4,101E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 5,535E-05 4,932E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 5,535E-05 4,756E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 5,535E-05 4,592E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 6,265E-05 5,025E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 6,545E-05 5,08E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 6,76E-05 5,083E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! Golgi vesicle budding GO:0048194 22 11 1,000 6,76E-05 4,929E-03 ! regulation of caspase activity GO:0043281 122 72 2,000 7,433E-05 5,26E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 7,433E-05 5,11E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 7,433E-05 4,968E-03 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,067E-05 5,245E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 8,107E-05 5,133E-03 ! positive regulation of ligase activity GO:0051351 124 77 2,000 9,082E-05 5,603E-03 ! regulation of peptidase activity GO:0052547 134 79 2,000 9,803E-05 5,896E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 9,803E-05 5,752E-03 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,018E-04 5,83E-03 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 1,095E-04 6,128E-03 ! response to nutrient GO:0007584 125 82 2,000 1,095E-04 5,989E-03 ! regulation of cyclase activity GO:0031279 159 82 2,000 1,095E-04 5,856E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,116E-04 5,838E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,116E-04 5,714E-03 ! regulation of lyase activity GO:0051339 160 83 2,000 1,135E-04 5,691E-03 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 1,177E-04 5,777E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 1,177E-04 5,662E-03 ! alcohol catabolic process GO:0046164 130 86 2,000 1,262E-04 5,953E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 1,287E-04 5,955E-03 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 1,306E-04 5,928E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 188 90 2,000 1,444E-04 6,434E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 1,444E-04 6,317E-03 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 1,47E-04 6,315E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,47E-04 6,204E-03 ! bone development GO:0060348 189 91 2,000 1,492E-04 6,19E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 1,591E-04 6,489E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 1,591E-04 6,381E-03 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 1,591E-04 6,277E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,665E-04 6,46E-03 ! membrane budding GO:0006900 37 17 1,000 1,665E-04 6,357E-03 ! regulation of protein binding GO:0043393 33 17 1,000 1,665E-04 6,258E-03 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 1,665E-04 6,162E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,695E-04 6,178E-03 ! interphase GO:0051325 213 98 2,000 1,858E-04 6,672E-03 ! skin development GO:0043588 36 19 1,000 2,09E-04 7,395E-03 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 2,09E-04 7,288E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,09E-04 7,184E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to lipopolysaccharide GO:0032496 30 19 1,000 2,09E-04 7,083E-03 ! visual learning GO:0008542 36 19 1,000 2,09E-04 6,984E-03 ! cell-cell junction organization GO:0045216 35 19 1,000 2,09E-04 6,888E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,321E-04 7,545E-03 ! cell aging GO:0007569 44 21 1,000 2,563E-04 8,222E-03 ! visual behavior GO:0007632 42 23 1,000 3,084E-04 9,762E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,084E-04 9,635E-03 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 3,084E-04 9,511E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 3,651E-04 0,01111988 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,651E-04 0,01098088 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,651E-04 0,01084532 ! fat cell differentiation GO:0045444 50 27 1,000 4,266E-04 0,01251655 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,591E-04 0,01330754 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 4,927E-04 0,01411314 ! eye morphogenesis GO:0048592 60 30 1,000 5,275E-04 0,01493275 ! protein targeting to membrane GO:0006612 68 33 1,000 6,39E-04 0,01787654 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 7,19E-04 0,01988527 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 7,19E-04 0,0196593 ! cell junction organization GO:0034330 86 36 1,000 7,608E-04 0,0205673 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 8,037E-04 0,02148579 ! mRNA catabolic process GO:0006402 71 39 1,000 8,93E-04 0,02360925 ! learning GO:0007612 77 39 1,000 8,93E-04 0,02335263 ! keratinocyte differentiation GO:0030216 62 41 1,000 9,868E-04 0,02552832 ! striated muscle cell differentiation GO:0051146 82 43 1,000 1,085E-03 0,02777393 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,188E-03 0,03008674 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 1,241E-03 0,03110468 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,241E-03 0,03078401 ! response to calcium ion GO:0051592 81 47 1,000 1,295E-03 0,03180163 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,351E-03 0,03282591 ! activation of caspase activity GO:0006919 84 48 1,000 1,351E-03 0,03249765 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 1,523E-03 0,03629202 ! vesicle organization GO:0016050 107 51 1,000 1,523E-03 0,03593622 ! positive regulation of growth GO:0045927 90 52 1,000 1,583E-03 0,03698468 ! RNA catabolic process GO:0006401 93 53 1,000 1,644E-03 0,03803861 ! response to UV GO:0009411 104 53 1,000 1,644E-03 0,03767634 ! positive regulation of caspase activity GO:0043280 95 55 1,000 1,769E-03 0,04016205 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 1,000 1,769E-03 0,03978671 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 2,033E-03 0,04528922 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 2,102E-03 0,04638833 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 2,102E-03 0,04596662 ! actin filament organization GO:0007015 148 66 1,000 2,536E-03 0,05497015 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 2,612E-03 0,05611601 ! negative regulation of kinase activity GO:0033673 131 68 1,000 2,689E-03 0,05726442 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 3,009E-03 0,06350968 ! negative regulation of transferase activity GO:0051348 140 72 1,000 3,009E-03 0,06295742 ! learning or memory GO:0007611 147 73 1,000 3,092E-03 0,06412759 ! eye development GO:0001654 143 74 1,000 3,175E-03 0,06529951 ! protein oligomerization GO:0051259 139 78 1,000 3,521E-03 0,07178262 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 3,609E-03 0,07297674 ! activation of protein kinase activity GO:0032147 147 79 1,000 3,609E-03 0,07236861 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 3,609E-03 0,07177052 ! regulation of synaptic transmission GO:0050804 134 79 1,000 3,609E-03 0,07118223 ! response to metal ion GO:0010038 140 80 1,000 3,699E-03 0,07236282 ! muscle cell differentiation GO:0042692 159 80 1,000 3,699E-03 0,07177925 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 3,79E-03 0,07295622 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 4,069E-03 0,07770798 ! mitochondrion organization GO:0007005 148 86 1,000 4,261E-03 0,08071983 ! response to inorganic substance GO:0010035 153 86 1,000 4,261E-03 0,0800892 ! positive regulation of protein modification process GO:0031401 136 88 1,000 4,456E-03 0,08311255 ! regulation of neurological system process GO:0031644 148 88 1,000 4,456E-03 0,08247322 ! Golgi vesicle transport GO:0048193 207 99 1,000 5,603E-03 0,10291506 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 5,632E-03 0,10266138 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,632E-03 0,10188949 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,632E-03 0,10112912 ! positive regulation of helicase activity GO:0051096 11 5 0,000 5,632E-03 0,10038002 ! neuron fate determination GO:0048664 7 5 0,000 5,632E-03 0,09964193 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,632E-03 0,09891462 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 5,632E-03 0,09819784 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,632E-03 0,09749138 ! polyol transport GO:0015791 12 5 0,000 5,632E-03 0,09679502 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 5,632E-03 0,09610853 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,632E-03 0,09543171 ! response to superoxide GO:0000303 10 5 0,000 5,632E-03 0,09476435 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,632E-03 0,09410627 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 5,632E-03 0,09345726 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 5,632E-03 0,09281714 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,632E-03 0,09218573 ! female meiosis GO:0007143 7 5 0,000 5,632E-03 0,09156285 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,632E-03 0,09094834 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,632E-03 0,09034202 ! cobalt ion transport GO:0006824 11 5 0,000 5,632E-03 0,08974372 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 5,632E-03 0,08915331 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 5,632E-03 0,0885706 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 5,632E-03 0,08799547 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,632E-03 0,08742776 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,632E-03 0,08686732 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 5,632E-03 0,08631403 ! embryonic camera-type eye development GO:0031076 10 5 0,000 5,632E-03 0,08576774 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,632E-03 0,08522832 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 5,632E-03 0,08469564 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 5,632E-03 0,08416958 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,632E-03 0,08365001 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,632E-03 0,08313682 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,632E-03 0,08262989 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 5,632E-03 0,08212911 ! negative chemotaxis GO:0050919 14 5 0,000 5,632E-03 0,08163435 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,632E-03 0,08114552 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,632E-03 0,08066251 ! sensory perception of bitter taste GO:0050913 7 5 0,000 5,632E-03 0,08018522 ! behavioral response to pain GO:0048266 9 5 0,000 5,632E-03 0,07971354 ! clathrin coat assembly GO:0048268 14 5 0,000 5,632E-03 0,07924738 ! Notch receptor processing GO:0007220 8 5 0,000 5,632E-03 0,07878664 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,632E-03 0,07833123 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,632E-03 0,07788105 ! micturition GO:0060073 9 5 0,000 5,632E-03 0,07743601 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,632E-03 0,07699604 ! copulation GO:0007620 9 5 0,000 5,632E-03 0,07656103 ! glial cell fate commitment GO:0021781 13 5 0,000 5,632E-03 0,07613091 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,632E-03 0,0757056 ! spermidine metabolic process GO:0008216 7 5 0,000 5,632E-03 0,07528501 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,632E-03 0,07486907 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,632E-03 0,07445771 ! apoptotic cell clearance GO:0043277 20 5 0,000 5,632E-03 0,07405083 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,632E-03 0,07364838 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,632E-03 0,07325028 ! grooming behavior GO:0007625 6 5 0,000 5,632E-03 0,07285646 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,632E-03 0,07246686 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 5,632E-03 0,0720814 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,632E-03 0,07170001 ! response to protozoan GO:0001562 10 5 0,000 5,632E-03 0,07132264 ! positive regulation of glycolysis GO:0045821 14 5 0,000 5,632E-03 0,07094923 ! lymph vessel development GO:0001945 10 5 0,000 5,632E-03 0,0705797 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 5,632E-03 0,070214 ! endochondral ossification GO:0001958 16 5 0,000 5,632E-03 0,06985207 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,632E-03 0,06949386 ! parathyroid gland development GO:0060017 13 5 0,000 5,632E-03 0,0691393 ! anagen GO:0042640 6 5 0,000 5,632E-03 0,06878834 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,632E-03 0,06844092 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,632E-03 0,068097 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 5,632E-03 0,06775651 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 5,632E-03 0,06741941 ! dorsal spinal cord development GO:0021516 7 5 0,000 5,632E-03 0,06708566 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 5,632E-03 0,06675518 ! sphingoid catabolic process GO:0046521 6 5 0,000 5,632E-03 0,06642795 ! skeletal myofibril assembly GO:0014866 10 5 0,000 5,632E-03 0,06610391 ! smooth muscle tissue development GO:0048745 28 5 0,000 5,632E-03 0,06578302 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,632E-03 0,06546523 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,632E-03 0,06515049 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,632E-03 0,06483877 ! cardiac muscle fiber development GO:0048739 10 5 0,000 5,632E-03 0,06453001 ! transepithelial chloride transport GO:0030321 9 5 0,000 5,632E-03 0,06422418 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,632E-03 0,06392124 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 5,632E-03 0,06362114 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 5,632E-03 0,06332384 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,632E-03 0,06302931 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,632E-03 0,06273751 ! histidine catabolic process GO:0006548 6 5 0,000 5,632E-03 0,0624484 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 5,632E-03 0,06216194 ! microvillus organization GO:0032528 7 5 0,000 5,632E-03 0,06187809 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 5,632E-03 0,06159683 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,632E-03 0,06131811 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,632E-03 0,0610419 ! tryptophan metabolic process GO:0006568 9 5 0,000 5,632E-03 0,06076817 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 5,632E-03 0,06049689 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,632E-03 0,06022801 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 5,632E-03 0,05996151 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,632E-03 0,05969737 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,632E-03 0,05943554 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,632E-03 0,05917599 ! muscle cell migration GO:0014812 8 5 0,000 5,632E-03 0,05891871 ! mitochondrial fission GO:0000266 8 5 0,000 5,632E-03 0,05866365 ! sister chromatid cohesion GO:0007062 12 5 0,000 5,632E-03 0,05841079 ! mRNA transcription GO:0009299 9 5 0,000 5,632E-03 0,0581601 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 5,632E-03 0,05791155 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 5,632E-03 0,05766512 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 5,632E-03 0,05742077 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,632E-03 0,05717849 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,632E-03 0,05693825 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,632E-03 0,05670001 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,632E-03 0,05646376 ! response to food GO:0032094 6 5 0,000 5,632E-03 0,05622947 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,632E-03 0,05599712 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,632E-03 0,05576668 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 5,632E-03 0,05553812 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,632E-03 0,05531144 ! paraxial mesoderm development GO:0048339 14 5 0,000 5,632E-03 0,0550866 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 5,632E-03 0,05486357 ! forebrain neuron development GO:0021884 13 5 0,000 5,632E-03 0,05464235 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,632E-03 0,0544229 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 5,632E-03 0,05420521 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,632E-03 0,05398925 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,632E-03 0,05377501 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,632E-03 0,05356246 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 5,632E-03 0,05335158 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,632E-03 0,05314236 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 5,632E-03 0,05293477 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 5,632E-03 0,0527288 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,632E-03 0,05252443 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 5,632E-03 0,05232163 ! basic amino acid transport GO:0015802 11 5 0,000 5,632E-03 0,05212039 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,632E-03 0,0519207 ! early endosome to late endosome transport GO:0045022 12 5 0,000 5,632E-03 0,05172253 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,632E-03 0,05152586 ! depyrimidination GO:0045008 10 5 0,000 5,632E-03 0,05133069 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,632E-03 0,05113699 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,632E-03 0,05094475 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,632E-03 0,05075394 ! zinc ion homeostasis GO:0055069 8 5 0,000 5,632E-03 0,05056456 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 5,632E-03 0,05037659 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 5,632E-03 0,05019001 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,632E-03 0,05000481 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,632E-03 0,04982096 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,632E-03 0,04963847 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 5,632E-03 0,04945731 ! peptidyl-arginine modification GO:0018195 9 5 0,000 5,632E-03 0,04927746 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,632E-03 0,04909892 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,632E-03 0,04892167 ! response to arsenic GO:0046685 10 5 0,000 5,632E-03 0,04874569 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,632E-03 0,04857098 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,632E-03 0,04839751 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 5,632E-03 0,04822528 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 5,632E-03 0,04805426 ! response to cadmium ion GO:0046686 7 5 0,000 5,632E-03 0,04788446 ! bile acid biosynthetic process GO:0006699 6 5 0,000 5,632E-03 0,04771585 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 5,632E-03 0,04754843 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,632E-03 0,04738218 ! decidualization GO:0046697 11 5 0,000 5,632E-03 0,04721708 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 5,632E-03 0,04705313 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 5,632E-03 0,04689032 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,632E-03 0,04672863 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,632E-03 0,04656805 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 5,632E-03 0,04640857 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,632E-03 0,04625018 ! neural tube patterning GO:0021532 7 5 0,000 5,632E-03 0,04609287 ! embryonic cleavage GO:0040016 6 5 0,000 5,632E-03 0,04593662 ! peroxisome fission GO:0016559 5 5 0,000 5,632E-03 0,04578143 ! histone demethylation GO:0016577 10 5 0,000 5,632E-03 0,04562728 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 5,632E-03 0,04547417 ! mitotic recombination GO:0006312 9 5 0,000 5,632E-03 0,04532208 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,632E-03 0,04517101 ! metaphase plate congression GO:0051310 7 5 0,000 5,632E-03 0,04502094 ! regulation of sterol transport GO:0032371 7 5 0,000 5,632E-03 0,04487186 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,632E-03 0,04472377 ! enteric nervous system development GO:0048484 8 5 0,000 5,632E-03 0,04457665 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 5,632E-03 0,0444305 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 5,632E-03 0,0442853 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 5,632E-03 0,04414105 ! muscle cell proliferation GO:0033002 11 5 0,000 5,632E-03 0,04399774 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,632E-03 0,04385535 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 5,632E-03 0,04371388 ! plasminogen activation GO:0031639 5 5 0,000 5,632E-03 0,04357332 ! B cell homeostasis GO:0001782 13 5 0,000 5,632E-03 0,04343366 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,632E-03 0,0432949 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,632E-03 0,04315701 ! metaphase GO:0051323 8 5 0,000 5,632E-03 0,04302001 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 5,632E-03 0,04288387 ! cellular response to nutrient GO:0031670 8 5 0,000 5,632E-03 0,04274859 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,632E-03 0,04261416 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,632E-03 0,04248057 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,632E-03 0,04234782 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 5,632E-03 0,0422159 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 5,632E-03 0,04208479 ! response to redox state GO:0051775 5 5 0,000 5,632E-03 0,0419545 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 5,632E-03 0,04182501 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 5,632E-03 0,04169632 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,632E-03 0,04156841 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,632E-03 0,04144129 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,632E-03 0,04131495 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 5,632E-03 0,04118937 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,632E-03 0,04106455 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 5,632E-03 0,04094049 ! striatum development GO:0021756 9 5 0,000 5,632E-03 0,04081718 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 5,632E-03 0,0406946 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 5,632E-03 0,04057276 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,632E-03 0,04045165 ! glial cell migration GO:0008347 11 5 0,000 5,632E-03 0,04033126 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,632E-03 0,04021158 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 5,632E-03 0,04009261 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,632E-03 0,03997434 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,632E-03 0,03985677 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,632E-03 0,03973989 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,632E-03 0,03962369 ! neuroprotection GO:0043526 6 5 0,000 5,632E-03 0,03950817 ! neural plate development GO:0001840 8 5 0,000 5,632E-03 0,03939332 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,632E-03 0,03927914 ! regulation of sensory perception GO:0051931 7 5 0,000 5,632E-03 0,03916561 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,632E-03 0,03905274 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,632E-03 0,03894052 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 5,632E-03 0,03882895 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 5,632E-03 0,03871801 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,632E-03 0,0386077 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,632E-03 0,03849802 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,632E-03 0,03838896 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,632E-03 0,03828052 ! spindle assembly GO:0051225 6 5 0,000 5,632E-03 0,03817268 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,632E-03 0,03806546 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,632E-03 0,03795883 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,632E-03 0,0378528 ! drug metabolic process GO:0017144 6 5 0,000 5,632E-03 0,03774736 ! stem cell division GO:0017145 11 5 0,000 5,632E-03 0,03764251 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,632E-03 0,03753823 ! organ regeneration GO:0031100 7 5 0,000 5,632E-03 0,03743454 ! carnitine metabolic process GO:0009437 7 5 0,000 5,632E-03 0,03733141 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 5,632E-03 0,03722885 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,632E-03 0,03712686 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,755E-03 0,04440617 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,755E-03 0,04428517 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 6,755E-03 0,04416483 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,755E-03 0,04404515 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,755E-03 0,04392611 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 6,755E-03 0,04380771 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 6,755E-03 0,04368994 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,755E-03 0,04357281 ! sleep GO:0030431 13 6 0,000 6,755E-03 0,04345631 ! response to oxygen radical GO:0000305 11 6 0,000 6,755E-03 0,04334042 ! positive regulation of axon extension GO:0045773 11 6 0,000 6,755E-03 0,04322516 ! myoblast cell fate commitment GO:0048625 16 6 0,000 6,755E-03 0,0431105 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 6,755E-03 0,04299645 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 6,755E-03 0,04288301 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,755E-03 0,04277016 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,755E-03 0,0426579 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 6,755E-03 0,04254623 ! forebrain regionalization GO:0021871 8 6 0,000 6,755E-03 0,04243514 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,755E-03 0,04232463 ! male meiosis GO:0007140 7 6 0,000 6,755E-03 0,0422147 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,755E-03 0,04210533 ! response to zinc ion GO:0010043 9 6 0,000 6,755E-03 0,04199654 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,755E-03 0,0418883 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 6,755E-03 0,04178061 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 6,755E-03 0,04167349 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,755E-03 0,0415669 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,755E-03 0,04146087 ! malate metabolic process GO:0006108 11 6 0,000 6,755E-03 0,04135537 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 6,755E-03 0,0412504 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 6,755E-03 0,04114597 ! protein refolding GO:0042026 15 6 0,000 6,755E-03 0,04104207 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,755E-03 0,04093869 ! opsonization GO:0008228 8 6 0,000 6,755E-03 0,04083583 ! mating behavior GO:0007617 7 6 0,000 6,755E-03 0,04073348 ! neuron remodeling GO:0016322 15 6 0,000 6,755E-03 0,04063165 ! erythrocyte maturation GO:0043249 7 6 0,000 6,755E-03 0,04053032 ! embryonic hemopoiesis GO:0035162 14 6 0,000 6,755E-03 0,0404295 ! equilibrioception GO:0050957 14 6 0,000 6,755E-03 0,04032918 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,755E-03 0,04022935 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 6,755E-03 0,04013002 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,755E-03 0,04003118 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,755E-03 0,03993282 ! response to interferon-gamma GO:0034341 15 6 0,000 6,755E-03 0,03983495 ! toxin metabolic process GO:0009404 11 6 0,000 6,755E-03 0,03973755 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,755E-03 0,03964063 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,755E-03 0,03954418 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 6,755E-03 0,0394482 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 6,755E-03 0,03935269 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 6,755E-03 0,03925763 ! cGMP-mediated signaling GO:0019934 13 6 0,000 6,755E-03 0,03916303 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,755E-03 0,03906889 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 6,755E-03 0,0389752 ! thymic T cell selection GO:0045061 12 6 0,000 6,755E-03 0,03888196 ! protein lipoylation GO:0009249 10 6 0,000 6,755E-03 0,03878916 ! cysteine metabolic process GO:0006534 10 6 0,000 6,755E-03 0,03869681 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,755E-03 0,03860489 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,755E-03 0,03851341 ! glutamate catabolic process GO:0006538 10 6 0,000 6,755E-03 0,03842236 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 6,755E-03 0,03833174 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,755E-03 0,03824155 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 6,755E-03 0,03815178 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 6,755E-03 0,03806243 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,755E-03 0,0379735 ! hyperosmotic response GO:0006972 9 6 0,000 6,755E-03 0,03788499 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 6,755E-03 0,03779688 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 6,755E-03 0,03770919 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,755E-03 0,0376219 ! urea metabolic process GO:0019627 7 6 0,000 6,755E-03 0,03753501 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,755E-03 0,03744852 ! neutrophil activation GO:0042119 8 6 0,000 6,755E-03 0,03736243 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,755E-03 0,03727674 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 6,755E-03 0,03719144 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,755E-03 0,03710653 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,755E-03 0,037022 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,755E-03 0,03693786 ! neuron apoptosis GO:0051402 9 6 0,000 6,755E-03 0,0368541 ! nucleoside salvage GO:0043174 9 6 0,000 6,755E-03 0,03677072 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 6,755E-03 0,03668772 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,755E-03 0,03660509 ! T cell mediated immunity GO:0002456 16 6 0,000 6,755E-03 0,03652283 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,755E-03 0,03644094 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 6,755E-03 0,03635942 ! carnitine transport GO:0015879 10 6 0,000 6,755E-03 0,03627826 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 6,755E-03 0,03619746 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,755E-03 0,03611702 ! positive regulation of exocytosis GO:0045921 8 6 0,000 6,755E-03 0,03603694 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 6,755E-03 0,03595721 ! 5S class rRNA transcription GO:0042791 11 6 0,000 6,755E-03 0,03587783 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,755E-03 0,03579881 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 6,755E-03 0,03572013 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 6,755E-03 0,0356418 ! sodium ion homeostasis GO:0055078 11 6 0,000 6,755E-03 0,03556381 ! establishment of spindle localization GO:0051293 12 6 0,000 6,755E-03 0,03548616 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,755E-03 0,03540884 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,755E-03 0,03533187 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 6,755E-03 0,03525523 ! neural nucleus development GO:0048857 14 6 0,000 6,755E-03 0,03517892 ! response to UV-C GO:0010225 11 6 0,000 6,755E-03 0,03510294 ! astrocyte development GO:0014002 15 6 0,000 6,755E-03 0,03502728 ! protein targeting to lysosome GO:0006622 10 6 0,000 6,755E-03 0,03495196 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,755E-03 0,03487695 ! interaction with symbiont GO:0051702 13 6 0,000 6,755E-03 0,03480227 ! regulation of dendrite development GO:0050773 16 6 0,000 6,755E-03 0,0347279 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,755E-03 0,03465386 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 6,755E-03 0,03458013 ! response to copper ion GO:0046688 10 6 0,000 6,755E-03 0,03450671 ! response to exogenous dsRNA GO:0043330 10 6 0,000 6,755E-03 0,0344336 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 6,755E-03 0,0343608 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,755E-03 0,03428831 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,755E-03 0,03421612 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,755E-03 0,03414424 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 6,755E-03 0,03407266 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,755E-03 0,03400138 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,755E-03 0,03393039 ! hair follicle maturation GO:0048820 7 6 0,000 6,755E-03 0,03385971 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,755E-03 0,03378931 ! Schwann cell development GO:0014044 15 6 0,000 6,755E-03 0,03371921 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,755E-03 0,0336494 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,755E-03 0,03357987 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 6,755E-03 0,03351064 ! subpallium development GO:0021544 10 6 0,000 6,755E-03 0,03344169 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 6,755E-03 0,03337302 ! histone ubiquitination GO:0016574 8 6 0,000 6,755E-03 0,03330463 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 6,755E-03 0,03323652 ! maintenance of organ identity GO:0048496 9 6 0,000 6,755E-03 0,03316869 ! G2 phase GO:0051319 16 6 0,000 6,755E-03 0,03310114 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 6,755E-03 0,03303386 ! establishment of planar polarity GO:0001736 7 6 0,000 6,755E-03 0,03296685 ! regulation of mast cell activation GO:0033003 12 6 0,000 6,755E-03 0,03290012 ! membrane to membrane docking GO:0022614 14 6 0,000 6,755E-03 0,03283365 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,755E-03 0,03276746 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 6,755E-03 0,03270153 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,755E-03 0,03263586 ! receptor internalization GO:0031623 10 6 0,000 6,755E-03 0,03257046 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 6,755E-03 0,03250532 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 6,755E-03 0,03244044 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,755E-03 0,03237582 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 6,755E-03 0,03231145 ! protein deubiquitination GO:0016579 14 6 0,000 6,755E-03 0,03224734 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 6,755E-03 0,03218348 ! protein destabilization GO:0031648 9 6 0,000 6,755E-03 0,03211988 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,755E-03 0,03205653 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 6,755E-03 0,03199342 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,755E-03 0,03193057 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 6,755E-03 0,03186796 ! progesterone metabolic process GO:0042448 10 6 0,000 6,755E-03 0,0318056 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 6,755E-03 0,03174347 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 6,755E-03 0,0316816 ! negative regulation of axon extension GO:0030517 21 6 0,000 6,755E-03 0,03161996 ! removal of superoxide radicals GO:0019430 11 6 0,000 6,755E-03 0,03155856 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,755E-03 0,0314974 ! determination of adult lifespan GO:0008340 15 6 0,000 6,755E-03 0,03143648 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 6,755E-03 0,03137579 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 6,755E-03 0,03131534 ! cerebellar cortex formation GO:0021697 8 6 0,000 6,755E-03 0,03125511 ! catecholamine transport GO:0051937 9 6 0,000 6,755E-03 0,03119512 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 6,755E-03 0,03113536 ! sensory cilium assembly GO:0035058 10 6 0,000 6,755E-03 0,03107583 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,755E-03 0,03101653 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 6,755E-03 0,03095745 ! maternal placenta development GO:0001893 12 6 0,000 6,755E-03 0,03089859 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 6,755E-03 0,03083996 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,755E-03 0,03078155 ! negative regulation of B cell activation GO:0050869 13 6 0,000 6,755E-03 0,03072336 ! protein amino acid prenylation GO:0018346 16 6 0,000 6,755E-03 0,03066539 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,755E-03 0,03060764 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 6,755E-03 0,03055011 ! positive regulation of coagulation GO:0050820 12 6 0,000 6,755E-03 0,03049279 ! tRNA transcription GO:0009304 14 7 0,000 7,877E-03 0,03548887 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 7,877E-03 0,03542253 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 7,877E-03 0,03535645 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,877E-03 0,03529061 ! regulation of helicase activity GO:0051095 15 7 0,000 7,877E-03 0,03522501 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,877E-03 0,03515966 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 7,877E-03 0,03509455 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,877E-03 0,03502968 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 7,877E-03 0,03496505 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,877E-03 0,03490065 ! prostate gland development GO:0030850 13 7 0,000 7,877E-03 0,0348365 ! nucleotide-sugar transport GO:0015780 12 7 0,000 7,877E-03 0,03477258 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,877E-03 0,03470889 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,877E-03 0,03464544 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 7,877E-03 0,03458222 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,877E-03 0,03451923 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 7,877E-03 0,03445646 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 7,877E-03 0,03439393 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 7,877E-03 0,03433162 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 7,877E-03 0,03426954 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,877E-03 0,03420768 ! SMAD protein complex assembly GO:0007183 12 7 0,000 7,877E-03 0,03414605 ! glycolipid transport GO:0046836 10 7 0,000 7,877E-03 0,03408463 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,877E-03 0,03402344 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,877E-03 0,03396246 ! neuron adhesion GO:0007158 12 7 0,000 7,877E-03 0,03390171 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 7,877E-03 0,03384117 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,877E-03 0,03378085 ! actin-myosin filament sliding GO:0033275 11 7 0,000 7,877E-03 0,03372074 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 7,877E-03 0,03366084 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 7,877E-03 0,03360116 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 7,877E-03 0,03354169 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 7,877E-03 0,03348243 ! mRNA stabilization GO:0048255 18 7 0,000 7,877E-03 0,03342338 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 7,877E-03 0,03336453 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 7,877E-03 0,0333059 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 7,877E-03 0,03324747 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,877E-03 0,03318924 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,877E-03 0,03313122 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,877E-03 0,0330734 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,877E-03 0,03301578 ! lipoprotein transport GO:0042953 14 7 0,000 7,877E-03 0,03295836 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,877E-03 0,03290114 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,877E-03 0,03284412 ! rhythmic behavior GO:0007622 15 7 0,000 7,877E-03 0,03278729 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 7,877E-03 0,03273067 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 7,877E-03 0,03267423 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 7,877E-03 0,032618 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,877E-03 0,03256195 ! regulation of odontogenesis GO:0042481 13 7 0,000 7,877E-03 0,0325061 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,877E-03 0,03245044 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 7,877E-03 0,03239497 ! mechanosensory behavior GO:0007638 14 7 0,000 7,877E-03 0,03233969 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 7,877E-03 0,03228459 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,877E-03 0,03222969 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 7,877E-03 0,03217497 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,877E-03 0,03212043 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,877E-03 0,03206608 ! spinal cord patterning GO:0021511 13 7 0,000 7,877E-03 0,03201192 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 7,877E-03 0,03195793 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,877E-03 0,03190413 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 7,877E-03 0,03185051 ! adrenal gland development GO:0030325 17 7 0,000 7,877E-03 0,03179707 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 7,877E-03 0,03174381 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 7,877E-03 0,03169073 ! ovulation GO:0030728 9 7 0,000 7,877E-03 0,03163782 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 7,877E-03 0,03158509 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,877E-03 0,03153254 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 7,877E-03 0,03148016 ! microtubule nucleation GO:0007020 20 7 0,000 7,877E-03 0,03142795 ! proline biosynthetic process GO:0006561 10 7 0,000 7,877E-03 0,03137592 ! thyroid hormone generation GO:0006590 13 7 0,000 7,877E-03 0,03132406 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 7,877E-03 0,03127237 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 7,877E-03 0,03122085 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 7,877E-03 0,0311695 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,877E-03 0,03111832 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,877E-03 0,0310673 ! galactose metabolic process GO:0006012 13 7 0,000 7,877E-03 0,03101646 ! vesicle fusion GO:0006906 17 7 0,000 7,877E-03 0,03096578 ! response to dietary excess GO:0002021 8 7 0,000 7,877E-03 0,03091526 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,877E-03 0,03086491 ! intracellular pH reduction GO:0051452 11 7 0,000 7,877E-03 0,03081472 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,877E-03 0,0307647 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 7,877E-03 0,03071484 ! organ growth GO:0035265 15 7 0,000 7,877E-03 0,03066514 ! purine salvage GO:0043101 10 7 0,000 7,877E-03 0,0306156 ! nucleoside transport GO:0015858 8 7 0,000 7,877E-03 0,03056622 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 7,877E-03 0,030517 ! parturition GO:0007567 14 7 0,000 7,877E-03 0,03046793 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 7,877E-03 0,03041903 ! rRNA modification GO:0000154 14 7 0,000 7,877E-03 0,03037028 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 7,877E-03 0,03032169 ! spindle checkpoint GO:0031577 15 7 0,000 7,877E-03 0,03027325 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 7,877E-03 0,03022497 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 7,877E-03 0,03017684 ! macrophage differentiation GO:0030225 11 7 0,000 7,877E-03 0,03012886 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,877E-03 0,03008104 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,877E-03 0,03003337 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 7,877E-03 0,02998585 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,877E-03 0,02993848 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 7,877E-03 0,02989125 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,877E-03 0,02984418 ! fibrinolysis GO:0042730 10 7 0,000 7,877E-03 0,02979726 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 7,877E-03 0,02975048 ! eating behavior GO:0042755 7 7 0,000 7,877E-03 0,02970385 ! B cell lineage commitment GO:0002326 21 7 0,000 7,877E-03 0,02965736 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,877E-03 0,02961102 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 7,877E-03 0,02956483 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 7,877E-03 0,02951878 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,877E-03 0,02947287 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 7,877E-03 0,0294271 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,877E-03 0,02938148 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 7,877E-03 0,029336 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 7,877E-03 0,02929066 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 7,877E-03 0,02924546 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 7,877E-03 0,02920039 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,877E-03 0,02915547 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 7,877E-03 0,02911068 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,877E-03 0,02906604 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,877E-03 0,02902152 ! regulation of meiosis GO:0040020 12 7 0,000 7,877E-03 0,02897715 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 7,877E-03 0,02893291 ! T cell lineage commitment GO:0002360 16 7 0,000 7,877E-03 0,0288888 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 7,877E-03 0,02884483 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,877E-03 0,028801 ! oxygen homeostasis GO:0032364 12 7 0,000 7,877E-03 0,02875729 ! transcription termination GO:0006353 13 7 0,000 7,877E-03 0,02871372 ! response to tumor cell GO:0002347 13 7 0,000 7,877E-03 0,02867028 ! regulation of respiratory burst GO:0060263 11 7 0,000 7,877E-03 0,02862697 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,877E-03 0,02858379 ! anaphase GO:0051322 17 7 0,000 7,877E-03 0,02854075 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 7,877E-03 0,02849783 ! axonal fasciculation GO:0007413 18 7 0,000 7,877E-03 0,02845504 ! negative regulation of nuclear division GO:0051784 14 7 0,000 7,877E-03 0,02841238 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 7,877E-03 0,02836984 ! diuresis GO:0030146 12 7 0,000 7,877E-03 0,02832744 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,877E-03 0,02828516 ! thiamin metabolic process GO:0006772 7 7 0,000 7,877E-03 0,028243 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,877E-03 0,02820098 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 7,877E-03 0,02815907 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 7,877E-03 0,02811729 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,877E-03 0,02807564 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,877E-03 0,02803411 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,877E-03 0,0279927 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,877E-03 0,02795141 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 7,877E-03 0,02791024 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,877E-03 0,0278692 ! glycolipid catabolic process GO:0019377 15 7 0,000 7,877E-03 0,02782828 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 7,877E-03 0,02778747 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 7,877E-03 0,02774679 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,877E-03 0,02770622 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 7,877E-03 0,02766577 ! endosome to lysosome transport GO:0008333 11 7 0,000 7,877E-03 0,02762545 ! protein modification by small protein removal GO:0070646 16 7 0,000 7,877E-03 0,02758523 ! adult feeding behavior GO:0008343 9 7 0,000 7,877E-03 0,02754514 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 7,877E-03 0,02750516 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 7,877E-03 0,0274653 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,877E-03 0,02742555 ! muscle adaptation GO:0043500 14 7 0,000 7,877E-03 0,02738592 ! embryonic heart tube development GO:0035050 10 7 0,000 7,877E-03 0,0273464 ! retina homeostasis GO:0001895 12 7 0,000 7,877E-03 0,027307 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,877E-03 0,02726771 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 7,877E-03 0,02722853 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 7,877E-03 0,02718946 ! protein prenylation GO:0018342 18 7 0,000 7,877E-03 0,02715051 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 7,877E-03 0,02711167 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 7,877E-03 0,02707294 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,877E-03 0,02703432 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 8,997E-03 0,03083546 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 8,997E-03 0,0307916 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 8,997E-03 0,03074786 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 8,997E-03 0,03070425 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 8,997E-03 0,03066076 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,997E-03 0,03061739 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,997E-03 0,03057414 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 8,997E-03 0,03053102 ! neutral lipid catabolic process GO:0046461 13 8 0,000 8,997E-03 0,03048802 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 8,997E-03 0,03044514 ! meiotic prophase I GO:0007128 13 8 0,000 8,997E-03 0,03040238 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,997E-03 0,03035974 ! oligopeptide transport GO:0006857 15 8 0,000 8,997E-03 0,03031722 ! UTP metabolic process GO:0046051 8 8 0,000 8,997E-03 0,03027482 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 8,997E-03 0,03023253 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 8,997E-03 0,03019037 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 8,997E-03 0,03014832 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,997E-03 0,03010639 ! succinate metabolic process GO:0006105 14 8 0,000 8,997E-03 0,03006458 ! membrane hyperpolarization GO:0060081 10 8 0,000 8,997E-03 0,03002288 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,997E-03 0,02998129 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 8,997E-03 0,02993983 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,997E-03 0,02989847 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 8,997E-03 0,02985723 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,997E-03 0,02981611 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,997E-03 0,0297751 ! ganglioside metabolic process GO:0001573 19 8 0,000 8,997E-03 0,0297342 ! reflex GO:0060004 16 8 0,000 8,997E-03 0,02969341 ! negative regulation of endocytosis GO:0045806 11 8 0,000 8,997E-03 0,02965273 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 8,997E-03 0,02961217 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,997E-03 0,02957171 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 8,997E-03 0,02953137 ! glycerolipid catabolic process GO:0046503 13 8 0,000 8,997E-03 0,02949114 ! hemoglobin metabolic process GO:0020027 13 8 0,000 8,997E-03 0,02945101 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,997E-03 0,029411 ! pigment granule organization GO:0048753 16 8 0,000 8,997E-03 0,02937109 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,997E-03 0,02933129 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 8,997E-03 0,0292916 ! astrocyte differentiation GO:0048708 18 8 0,000 8,997E-03 0,02925202 ! histidine metabolic process GO:0006547 16 8 0,000 8,997E-03 0,02921254 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,997E-03 0,02917317 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 8,997E-03 0,02913391 ! glycine catabolic process GO:0006546 13 8 0,000 8,997E-03 0,02909475 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 8,997E-03 0,0290557 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 8,997E-03 0,02901675 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 8,997E-03 0,0289779 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 8,997E-03 0,02893916 ! regulation of pigmentation during development GO:0048070 24 8 0,000 8,997E-03 0,02890053 ! melanin metabolic process GO:0006582 15 8 0,000 8,997E-03 0,02886199 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 8,997E-03 0,02882356 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 8,997E-03 0,02878523 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,997E-03 0,028747 ! macrophage activation GO:0042116 12 8 0,000 8,997E-03 0,02870888 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,997E-03 0,02867085 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,997E-03 0,02863293 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 8,997E-03 0,0285951 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,997E-03 0,02855738 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,997E-03 0,02851976 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 8,997E-03 0,02848223 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,997E-03 0,0284448 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 8,997E-03 0,02840747 ! osteoblast development GO:0002076 16 8 0,000 8,997E-03 0,02837024 ! positive regulation of vasodilation GO:0045909 13 8 0,000 8,997E-03 0,02833311 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,997E-03 0,02829607 ! negative regulation of translational initiation GO:0045947 10 8 0,000 8,997E-03 0,02825913 ! Schwann cell differentiation GO:0014037 19 8 0,000 8,997E-03 0,02822229 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 8,997E-03 0,02818554 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,997E-03 0,02814889 ! response to UV-B GO:0010224 16 8 0,000 8,997E-03 0,02811233 ! protein targeting to vacuole GO:0006623 12 8 0,000 8,997E-03 0,02807587 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,997E-03 0,0280395 ! intermediate filament organization GO:0045109 12 8 0,000 8,997E-03 0,02800323 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 8,997E-03 0,02796705 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 8,997E-03 0,02793096 ! cellular extravasation GO:0045123 12 8 0,000 8,997E-03 0,02789497 ! cardiac muscle cell development GO:0055013 13 8 0,000 8,997E-03 0,02785907 ! regulation of circadian rhythm GO:0042752 16 8 0,000 8,997E-03 0,02782326 ! response to antibiotic GO:0046677 11 8 0,000 8,997E-03 0,02778754 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 8,997E-03 0,02775192 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 8,997E-03 0,02771638 ! DNA topological change GO:0006265 12 8 0,000 8,997E-03 0,02768094 ! response to tropane GO:0014073 15 8 0,000 8,997E-03 0,02764559 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 8,997E-03 0,02761032 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 8,997E-03 0,02757515 ! melanosome transport GO:0032402 13 8 0,000 8,997E-03 0,02754007 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 8,997E-03 0,02750508 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 8,997E-03 0,02747017 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,997E-03 0,02743535 ! mast cell activation GO:0045576 14 8 0,000 8,997E-03 0,02740063 ! multicellular organismal aging GO:0010259 18 8 0,000 8,997E-03 0,02736599 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 8,997E-03 0,02733143 ! dendrite morphogenesis GO:0048813 13 8 0,000 8,997E-03 0,02729697 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 8,997E-03 0,02726259 ! nucleosome disassembly GO:0006337 14 8 0,000 8,997E-03 0,02722829 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,997E-03 0,02719409 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 8,997E-03 0,02715997 ! leukocyte activation during immune response GO:0002366 13 8 0,000 8,997E-03 0,02712593 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,997E-03 0,02709198 ! establishment of chromosome localization GO:0051303 12 8 0,000 8,997E-03 0,02705812 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 8,997E-03 0,02702434 ! intracellular lipid transport GO:0032365 13 8 0,000 8,997E-03 0,02699064 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,997E-03 0,02695703 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 8,997E-03 0,0269235 ! regulation of macrophage activation GO:0043030 15 8 0,000 8,997E-03 0,02689006 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,997E-03 0,02685669 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 8,997E-03 0,02682341 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 8,997E-03 0,02679022 ! hormone catabolic process GO:0042447 17 8 0,000 8,997E-03 0,0267571 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,997E-03 0,02672407 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 8,997E-03 0,02669112 ! ATP catabolic process GO:0006200 11 8 0,000 8,997E-03 0,02665824 ! blastocyst growth GO:0001832 19 8 0,000 8,997E-03 0,02662545 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,997E-03 0,02659274 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,997E-03 0,02656012 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 8,997E-03 0,02652757 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,997E-03 0,0264951 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 8,997E-03 0,02646271 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 8,997E-03 0,0264304 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 8,997E-03 0,02639816 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 8,997E-03 0,02636601 ! amino sugar catabolic process GO:0046348 10 8 0,000 8,997E-03 0,02633393 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 8,997E-03 0,02630194 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,997E-03 0,02627002 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,997E-03 0,02623817 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,997E-03 0,02620641 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,997E-03 0,02617472 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,997E-03 0,02614311 ! NAD biosynthetic process GO:0009435 13 8 0,000 8,997E-03 0,02611157 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01011595 0,02932407 ! axon extension GO:0048675 15 9 0,000 0,01011595 0,02928878 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01011595 0,02925358 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01011595 0,02921846 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01011595 0,02918343 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01011595 0,02914848 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01011595 0,02911361 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01011595 0,02907883 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01011595 0,02904413 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01011595 0,02900951 ! phosphate transport GO:0006817 19 9 0,000 0,01011595 0,02897497 ! reproductive behavior GO:0019098 19 9 0,000 0,01011595 0,02894052 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01011595 0,02890615 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01011595 0,02887186 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01011595 0,02883765 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01011595 0,02880353 ! GTP metabolic process GO:0046039 9 9 0,000 0,01011595 0,02876948 ! RNA methylation GO:0001510 15 9 0,000 0,01011595 0,02873551 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01011595 0,02870163 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01011595 0,02866782 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01011595 0,02863409 ! artery development GO:0060840 24 9 0,000 0,01011595 0,02860045 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01011595 0,02856688 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01011595 0,02853339 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01011595 0,02849998 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01011595 0,02846664 ! chemosensory behavior GO:0007635 20 9 0,000 0,01011595 0,02843339 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01011595 0,02840021 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01011595 0,02836711 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01011595 0,02833408 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01011595 0,02830114 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01011595 0,02826827 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01011595 0,02823547 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01011595 0,02820276 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01011595 0,02817011 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01011595 0,02813755 ! protein targeting to ER GO:0045047 22 9 0,000 0,01011595 0,02810506 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01011595 0,02807264 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01011595 0,0280403 ! T cell selection GO:0045058 23 9 0,000 0,01011595 0,02800803 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01011595 0,02797584 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01011595 0,02794372 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01011595 0,02791167 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01011595 0,0278797 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01011595 0,0278478 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01011595 0,02781598 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01011595 0,02778422 ! mannose metabolic process GO:0006013 13 9 0,000 0,01011595 0,02775254 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01011595 0,02772093 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01011595 0,0276894 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01011595 0,02765793 ! receptor clustering GO:0043113 18 9 0,000 0,01011595 0,02762654 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01011595 0,02759521 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01011595 0,02756396 ! ruffle organization GO:0031529 15 9 0,000 0,01011595 0,02753278 ! retinol metabolic process GO:0042572 18 9 0,000 0,01011595 0,02750167 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01011595 0,02747063 ! behavioral fear response GO:0001662 22 9 0,000 0,01011595 0,02743966 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01011595 0,02740876 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01011595 0,02737793 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01011595 0,02734717 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01011595 0,02731647 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01011595 0,02728585 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01011595 0,0272553 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01011595 0,02722481 ! segment specification GO:0007379 13 9 0,000 0,01011595 0,02719439 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01011595 0,02716404 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01011595 0,02713376 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01011595 0,02710354 ! response to amine stimulus GO:0014075 13 9 0,000 0,01011595 0,02707339 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01011595 0,02704331 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01011595 0,0270133 ! erythrocyte development GO:0048821 15 9 0,000 0,01011595 0,02698335 ! gas homeostasis GO:0033483 16 9 0,000 0,01011595 0,02695347 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01011595 0,02692365 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01011595 0,0268939 ! renal water homeostasis GO:0003091 14 9 0,000 0,01011595 0,02686422 ! postreplication repair GO:0006301 22 9 0,000 0,01011595 0,0268346 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01011595 0,02680504 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01011595 0,02677555 ! icosanoid secretion GO:0032309 15 9 0,000 0,01011595 0,02674613 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01011595 0,02671677 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01011595 0,02668748 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01011595 0,02665825 ! regulation of cell division GO:0051302 15 9 0,000 0,01011595 0,02662908 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01011595 0,02659998 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01011595 0,02657094 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01011595 0,02654196 ! sterol catabolic process GO:0016127 11 9 0,000 0,01011595 0,02651305 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01011595 0,0264842 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01011595 0,02645541 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01011595 0,02642669 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01011595 0,02639802 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01011595 0,02636942 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01011595 0,02634089 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01011595 0,02631241 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01011595 0,02628399 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01011595 0,02625564 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01011595 0,02622735 ! purine base metabolic process GO:0006144 21 9 0,000 0,01011595 0,02619912 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01011595 0,02617095 ! pigment granule transport GO:0051904 17 9 0,000 0,01011595 0,02614283 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01011595 0,02611478 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01011595 0,02608679 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01011595 0,02605886 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01011595 0,02603099 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01011595 0,02600318 ! mitochondrion localization GO:0051646 15 9 0,000 0,01011595 0,02597543 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0112338 0,02881505 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,0112338 0,02878436 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0112338 0,02875374 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0112338 0,02872318 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,0112338 0,02869269 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0112338 0,02866226 ! synapsis GO:0007129 13 10 0,000 0,0112338 0,0286319 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0112338 0,0286016 ! N-glycan processing GO:0006491 20 10 0,000 0,0112338 0,02857137 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0112338 0,0285412 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0112338 0,02851109 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0112338 0,02848105 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0112338 0,02845107 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0112338 0,02842115 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0112338 0,02839129 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0112338 0,0283615 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0112338 0,02833177 ! androgen metabolic process GO:0008209 17 10 0,000 0,0112338 0,02830211 ! phospholipid efflux GO:0033700 16 10 0,000 0,0112338 0,0282725 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0112338 0,02824296 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0112338 0,02821348 ! lung alveolus development GO:0048286 26 10 0,000 0,0112338 0,02818406 ! pathogenesis GO:0009405 13 10 0,000 0,0112338 0,0281547 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0112338 0,0281254 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0112338 0,02809617 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0112338 0,02806699 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0112338 0,02803788 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0112338 0,02800882 ! endoderm development GO:0007492 16 10 0,000 0,0112338 0,02797983 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0112338 0,02795089 ! arginine catabolic process GO:0006527 13 10 0,000 0,0112338 0,02792202 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0112338 0,0278932 ! proline metabolic process GO:0006560 13 10 0,000 0,0112338 0,02786445 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0112338 0,02783575 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0112338 0,02780711 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0112338 0,02777853 ! V(D)J recombination GO:0033151 28 10 0,000 0,0112338 0,02775001 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0112338 0,02772155 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0112338 0,02769315 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0112338 0,0276648 ! B cell proliferation GO:0042100 18 10 0,000 0,0112338 0,02763652 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0112338 0,02760829 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0112338 0,02758011 ! multicellular organism growth GO:0035264 18 10 0,000 0,0112338 0,027552 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0112338 0,02752394 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0112338 0,02749594 ! epithelial cell development GO:0002064 20 10 0,000 0,0112338 0,027468 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0112338 0,02744011 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0112338 0,02741228 ! macroautophagy GO:0016236 17 10 0,000 0,0112338 0,02738451 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0112338 0,02735679 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0112338 0,02732913 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0112338 0,02730153 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0112338 0,02727398 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0112338 0,02724648 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0112338 0,02721905 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0112338 0,02719166 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0112338 0,02716433 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0112338 0,02713706 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0112338 0,02710984 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0112338 0,02708268 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0112338 0,02705557 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0112338 0,02702851 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0112338 0,02700151 ! response to dsRNA GO:0043331 20 10 0,000 0,0112338 0,02697456 ! DNA ligation GO:0006266 19 10 0,000 0,0112338 0,02694767 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0112338 0,02692083 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0112338 0,02689404 ! melanosome localization GO:0032400 16 10 0,000 0,0112338 0,02686731 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0112338 0,02684063 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0112338 0,026814 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0112338 0,02678743 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0112338 0,0267609 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0112338 0,02673443 ! mRNA cleavage GO:0006379 17 10 0,000 0,0112338 0,02670802 ! protein sumoylation GO:0016925 15 10 0,000 0,0112338 0,02668165 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0112338 0,02665534 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0112338 0,02662908 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0112338 0,02660287 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0112338 0,02657671 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0112338 0,0265506 ! salivary gland development GO:0007431 27 10 0,000 0,0112338 0,02652455 ! prophase GO:0051324 15 10 0,000 0,0112338 0,02649854 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0112338 0,02647259 ! apical protein localization GO:0045176 15 10 0,000 0,0112338 0,02644669 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0112338 0,02642083 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0112338 0,02639503 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0112338 0,02636928 ! midbrain development GO:0030901 13 10 0,000 0,0112338 0,02634358 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0112338 0,02631793 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0112338 0,02629233 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0112338 0,02626678 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0112338 0,02624127 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0112338 0,02621582 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0112338 0,02619042 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0112338 0,02616507 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0112338 0,02613976 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0112338 0,0261145 ! oocyte development GO:0048599 17 10 0,000 0,0112338 0,0260893 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0112338 0,02606414 ! blastocyst formation GO:0001825 17 10 0,000 0,0112338 0,02603903 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0112338 0,02601397 ! activation of innate immune response GO:0002218 12 10 0,000 0,0112338 0,02598895 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0112338 0,02596399 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0112338 0,02593907 ! response to nicotine GO:0035094 20 10 0,000 0,0112338 0,0259142 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0112338 0,02588938 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0112338 0,02586461 ! localization within membrane GO:0051668 20 10 0,000 0,0112338 0,02583988 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01235041 0,02838118 ! respiratory burst GO:0045730 17 11 0,000 0,01235041 0,0283541 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01235041 0,02832707 ! neuron fate specification GO:0048665 17 11 0,000 0,01235041 0,02830009 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01235041 0,02827317 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01235041 0,02824629 ! thyroid gland development GO:0030878 26 11 0,000 0,01235041 0,02821947 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01235041 0,02819269 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01235041 0,02816597 ! response to pain GO:0048265 24 11 0,000 0,01235041 0,0281393 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01235041 0,02811268 ! T cell proliferation GO:0042098 26 11 0,000 0,01235041 0,0280861 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01235041 0,02805958 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01235041 0,02803311 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01235041 0,02800669 ! bone resorption GO:0045453 16 11 0,000 0,01235041 0,02798032 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01235041 0,027954 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01235041 0,02792772 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01235041 0,0279015 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01235041 0,02787533 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01235041 0,0278492 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01235041 0,02782313 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01235041 0,0277971 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01235041 0,02777112 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01235041 0,02774519 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01235041 0,02771931 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01235041 0,02769347 ! lipid digestion GO:0044241 18 11 0,000 0,01235041 0,02766769 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01235041 0,02764195 ! UV protection GO:0009650 19 11 0,000 0,01235041 0,02761626 ! adult heart development GO:0007512 14 11 0,000 0,01235041 0,02759062 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01235041 0,02756503 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01235041 0,02753948 ! temperature homeostasis GO:0001659 17 11 0,000 0,01235041 0,02751398 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01235041 0,02748853 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01235041 0,02746312 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01235041 0,02743776 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01235041 0,02741245 ! regulation of organ growth GO:0046620 13 11 0,000 0,01235041 0,02738719 ! pigment granule localization GO:0051875 20 11 0,000 0,01235041 0,02736197 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01235041 0,0273368 ! vasoconstriction GO:0042310 18 11 0,000 0,01235041 0,02731167 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01235041 0,02728659 ! embryonic axis specification GO:0000578 18 11 0,000 0,01235041 0,02726156 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01235041 0,02723657 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01235041 0,02721163 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01235041 0,02718673 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01235041 0,02716188 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01235041 0,02713708 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01235041 0,02711232 ! zymogen activation GO:0031638 15 11 0,000 0,01235041 0,0270876 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01235041 0,02706293 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01235041 0,02703831 ! nucleosome positioning GO:0016584 15 11 0,000 0,01235041 0,02701373 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01235041 0,02698919 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01235041 0,0269647 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01235041 0,02694025 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01235041 0,02691585 ! acid secretion GO:0046717 18 11 0,000 0,01235041 0,02689149 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01235041 0,02686718 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01235041 0,02684291 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01235041 0,02681868 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01235041 0,0267945 ! oocyte differentiation GO:0009994 18 11 0,000 0,01235041 0,02677036 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01235041 0,02674626 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01235041 0,02672221 ! cholesterol efflux GO:0033344 19 11 0,000 0,01235041 0,0266982 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01235041 0,02667424 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01235041 0,02665031 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01235041 0,02662643 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01235041 0,02660259 ! embryonic gut development GO:0048566 15 11 0,000 0,01235041 0,0265788 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01235041 0,02655505 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01235041 0,02653134 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01235041 0,02650767 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01235041 0,02648404 ! defense response to fungus GO:0050832 13 11 0,000 0,01235041 0,02646046 ! developmental induction GO:0031128 19 11 0,000 0,01235041 0,02643692 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01235041 0,02641342 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01235041 0,02638996 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01235041 0,02636655 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01235041 0,02634317 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01235041 0,02631984 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01235041 0,02629655 ! nucleus localization GO:0051647 19 11 0,000 0,01235041 0,0262733 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01235041 0,02625009 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01346581 0,02859553 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01346581 0,02857032 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01346581 0,02854514 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01346581 0,02852002 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01346581 0,02849493 ! virus-host interaction GO:0019048 29 12 0,000 0,01346581 0,02846989 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01346581 0,0284449 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01346581 0,02841995 ! cartilage condensation GO:0001502 20 12 0,000 0,01346581 0,02839504 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01346581 0,02837017 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01346581 0,02834535 ! protein complex disassembly GO:0043241 27 12 0,000 0,01346581 0,02832058 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01346581 0,02829584 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01346581 0,02827115 ! hippocampus development GO:0021766 26 12 0,000 0,01346581 0,0282465 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01346581 0,0282219 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01346581 0,02819734 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01346581 0,02817282 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01346581 0,02814834 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01346581 0,02812391 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01346581 0,02809951 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01346581 0,02807516 ! drug transport GO:0015893 16 12 0,000 0,01346581 0,02805086 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01346581 0,02802659 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01346581 0,02800237 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01346581 0,02797819 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01346581 0,02795405 ! focal adhesion formation GO:0048041 35 12 0,000 0,01346581 0,02792995 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01346581 0,02790589 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01346581 0,02788187 ! forebrain cell migration GO:0021885 21 12 0,000 0,01346581 0,0278579 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01346581 0,02783397 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01346581 0,02781008 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01346581 0,02778623 ! entry into host cell GO:0030260 32 12 0,000 0,01346581 0,02776242 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01346581 0,02773865 ! monoamine transport GO:0015844 18 12 0,000 0,01346581 0,02771492 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01346581 0,02769123 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01346581 0,02766758 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01346581 0,02764397 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01346581 0,02762041 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01346581 0,02759688 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01346581 0,02757339 ! protein homotetramerization GO:0051289 21 12 0,000 0,01346581 0,02754995 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01346581 0,02752654 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01346581 0,02750317 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01346581 0,02747985 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01346581 0,02745656 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01346581 0,02743331 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01346581 0,0274101 ! cranial nerve development GO:0021545 20 12 0,000 0,01346581 0,02738693 ! fucose catabolic process GO:0019317 22 12 0,000 0,01346581 0,0273638 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01346581 0,02734071 ! histone acetylation GO:0016573 26 12 0,000 0,01346581 0,02731765 ! histone methylation GO:0016571 26 12 0,000 0,01346581 0,02729464 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01346581 0,02727167 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01346581 0,02724873 ! gland morphogenesis GO:0022612 29 12 0,000 0,01346581 0,02722583 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01346581 0,02720297 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01346581 0,02718015 ! T cell homeostasis GO:0043029 25 12 0,000 0,01346581 0,02715737 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01346581 0,02713462 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01346581 0,02711192 ! spleen development GO:0048536 22 12 0,000 0,01346581 0,02708925 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01346581 0,02706662 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01346581 0,02704402 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01346581 0,02702147 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01346581 0,02699895 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01346581 0,02697647 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01346581 0,02695403 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01346581 0,02693162 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01346581 0,02690925 ! response to cold GO:0009409 17 12 0,000 0,01346581 0,02688692 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01346581 0,02686463 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01346581 0,02684237 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01457998 0,02903927 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01457998 0,02901525 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01457998 0,02899127 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01457998 0,02896733 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01457998 0,02894343 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01457998 0,02891957 ! lipid localization GO:0010876 28 13 0,000 0,01457998 0,02889575 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01457998 0,02887197 ! organelle fusion GO:0048284 32 13 0,000 0,01457998 0,02884822 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01457998 0,02882452 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01457998 0,02880085 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01457998 0,02877723 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01457998 0,02875364 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01457998 0,02873009 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01457998 0,02870658 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01457998 0,02868311 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01457998 0,02865967 ! methionine metabolic process GO:0006555 27 13 0,000 0,01457998 0,02863628 ! plasma membrane organization GO:0007009 24 13 0,000 0,01457998 0,02861292 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01457998 0,0285896 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01457998 0,02856632 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01457998 0,02854307 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01457998 0,02851987 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01457998 0,0284967 ! response to X-ray GO:0010165 25 13 0,000 0,01457998 0,02847357 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01457998 0,02845048 ! exocrine system development GO:0035272 32 13 0,000 0,01457998 0,02842742 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01457998 0,0284044 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01457998 0,02838142 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01457998 0,02835848 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01457998 0,02833557 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01457998 0,0283127 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01457998 0,02828987 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01457998 0,02826707 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01457998 0,02824431 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01457998 0,02822159 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01457998 0,0281989 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01457998 0,02817626 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01457998 0,02815364 ! ribosome assembly GO:0042255 17 13 0,000 0,01457998 0,02813106 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01457998 0,02810852 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01457998 0,02808602 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01457998 0,02806355 ! chromatin silencing GO:0006342 26 13 0,000 0,01457998 0,02804112 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01457998 0,02801872 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01457998 0,02799636 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01457998 0,02797403 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01457998 0,02795174 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01457998 0,02792949 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01457998 0,02790727 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01457998 0,02788509 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01457998 0,02786294 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01457998 0,02784082 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01457998 0,02781875 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01457998 0,0277967 ! embryonic placenta development GO:0001892 23 13 0,000 0,01457998 0,02777469 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01457998 0,02775272 ! insulin secretion GO:0030073 23 13 0,000 0,01457998 0,02773078 ! actin filament polymerization GO:0030041 24 13 0,000 0,01457998 0,02770888 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01457998 0,02768701 ! acrosome reaction GO:0007340 18 13 0,000 0,01457998 0,02766517 ! rRNA transcription GO:0009303 25 14 0,000 0,01569293 0,02975351 ! lactation GO:0007595 26 14 0,000 0,01569293 0,02973008 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01569293 0,02970669 ! reproductive cellular process GO:0048610 20 14 0,000 0,01569293 0,02968333 ! tRNA modification GO:0006400 20 14 0,000 0,01569293 0,02966001 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01569293 0,02963673 ! regulation of S phase GO:0033261 23 14 0,000 0,01569293 0,02961349 ! water transport GO:0006833 21 14 0,000 0,01569293 0,02959028 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01569293 0,02956711 ! non-recombinational repair GO:0000726 25 14 0,000 0,01569293 0,02954397 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01569293 0,02952087 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01569293 0,02949781 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01569293 0,02947478 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01569293 0,02945179 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01569293 0,02942884 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01569293 0,02940592 ! palate development GO:0060021 31 14 0,000 0,01569293 0,02938303 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01569293 0,02936019 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01569293 0,02933737 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01569293 0,02931459 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01569293 0,02929185 ! arginine metabolic process GO:0006525 17 14 0,000 0,01569293 0,02926915 ! regulation of heart rate GO:0002027 24 14 0,000 0,01569293 0,02924647 ! organic alcohol transport GO:0015850 29 14 0,000 0,01569293 0,02922384 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01569293 0,02920124 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01569293 0,02917867 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01569293 0,02915614 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01569293 0,02913364 ! L-amino acid transport GO:0015807 30 14 0,000 0,01569293 0,02911118 ! bone mineralization GO:0030282 17 14 0,000 0,01569293 0,02908875 ! stem cell development GO:0048864 43 14 0,000 0,01569293 0,02906636 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01569293 0,029044 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01569293 0,02902167 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01569293 0,02899938 ! cerebellum development GO:0021549 21 14 0,000 0,01569293 0,02897713 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01569293 0,02895491 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01569293 0,02893272 ! response to gamma radiation GO:0010332 28 14 0,000 0,01569293 0,02891057 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01569293 0,02888845 ! cofactor transport GO:0051181 26 14 0,000 0,01569293 0,02886636 ! NADP metabolic process GO:0006739 24 14 0,000 0,01569293 0,02884431 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01569293 0,02882229 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01569293 0,0288003 ! intestinal absorption GO:0050892 25 14 0,000 0,01569293 0,02877835 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01569293 0,02875643 ! oxygen transport GO:0015671 21 14 0,000 0,01569293 0,02873455 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01569293 0,0287127 ! male genitalia development GO:0030539 24 14 0,000 0,01569293 0,02869088 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01569293 0,02866909 ! regulation of axon extension GO:0030516 37 14 0,000 0,01569293 0,02864734 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01569293 0,02862562 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01680466 0,03063032 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01680466 0,03060713 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01680466 0,03058398 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01680466 0,03056086 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01680466 0,03053778 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01680466 0,03051473 ! copper ion transport GO:0006825 20 15 0,000 0,01680466 0,03049172 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01680466 0,03046874 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01680466 0,0304458 ! sulfate transport GO:0008272 23 15 0,000 0,01680466 0,03042289 ! response to cAMP GO:0051591 22 15 0,000 0,01680466 0,03040002 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01680466 0,03037718 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01680466 0,03035437 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01680466 0,0303316 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01680466 0,03030886 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01680466 0,03028616 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01680466 0,03026349 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01680466 0,03024085 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01680466 0,03021825 ! pituitary gland development GO:0021983 29 15 0,000 0,01680466 0,03019569 ! vesicle coating GO:0006901 33 15 0,000 0,01680466 0,03017315 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01680466 0,03015065 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01680466 0,03012818 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01680466 0,03010575 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01680466 0,03008335 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01680466 0,03006098 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01680466 0,03003865 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01680466 0,03001635 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01680466 0,02999408 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01680466 0,02997185 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01680466 0,02994965 ! histone deacetylation GO:0016575 20 15 0,000 0,01680466 0,02992748 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01680466 0,02990534 ! tissue regeneration GO:0042246 26 15 0,000 0,01680466 0,02988324 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01680466 0,02986117 ! water homeostasis GO:0030104 27 15 0,000 0,01680466 0,02983913 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01680466 0,02981713 ! muscle maintenance GO:0046716 26 15 0,000 0,01680466 0,02979515 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01680466 0,02977321 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01680466 0,0297513 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01680466 0,02972943 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01680466 0,02970758 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01680466 0,02968577 ! cell killing GO:0001906 29 15 0,000 0,01680466 0,02966399 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01680466 0,02964225 ! detection of bacterium GO:0016045 18 15 0,000 0,01680466 0,02962053 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01680466 0,02959885 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01680466 0,02957719 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01680466 0,02955557 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01680466 0,02953398 ! peptide hormone processing GO:0016486 23 15 0,000 0,01680466 0,02951243 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01791518 0,03143976 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01791518 0,03141685 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01791518 0,03139397 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01791518 0,03137112 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01791518 0,0313483 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01791518 0,03132552 ! bone remodeling GO:0046849 27 16 0,000 0,01791518 0,03130277 ! filopodium assembly GO:0046847 32 16 0,000 0,01791518 0,03128005 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01791518 0,03125737 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01791518 0,03123472 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01791518 0,0312121 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01791518 0,03118952 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01791518 0,03116697 ! startle response GO:0001964 28 16 0,000 0,01791518 0,03114445 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01791518 0,03112196 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01791518 0,03109951 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01791518 0,03107708 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01791518 0,03105469 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01791518 0,03103234 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01791518 0,03101001 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01791518 0,03098772 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01791518 0,03096546 ! response to osmotic stress GO:0006970 25 16 0,000 0,01791518 0,03094323 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01791518 0,03092103 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01791518 0,03089886 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01791518 0,03087673 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01791518 0,03085463 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01791518 0,03083256 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01791518 0,03081052 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01791518 0,03078851 ! axon cargo transport GO:0008088 43 16 0,000 0,01791518 0,03076654 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01791518 0,03074459 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01791518 0,03072268 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01791518 0,03070079 ! DNA replication initiation GO:0006270 27 16 0,000 0,01791518 0,03067894 ! neuron recognition GO:0008038 35 16 0,000 0,01791518 0,03065712 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01791518 0,03063533 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01791518 0,03061358 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01791518 0,03059185 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01791518 0,03057015 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01791518 0,03054849 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01791518 0,03052685 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01791518 0,03050525 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01791518 0,03048367 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01791518 0,03046213 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01791518 0,03044062 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01791518 0,03041914 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01791518 0,03039768 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,01791518 0,03037626 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01902447 0,03223442 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01902447 0,03221174 ! metencephalon development GO:0022037 30 17 0,000 0,01902447 0,03218909 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01902447 0,03216646 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01902447 0,03214388 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01902447 0,03212132 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01902447 0,03209879 ! signal complex assembly GO:0007172 41 17 0,000 0,01902447 0,0320763 ! endothelial cell migration GO:0043542 28 17 0,000 0,01902447 0,03205384 ! inositol metabolic process GO:0006020 28 17 0,000 0,01902447 0,03203141 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01902447 0,03200901 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01902447 0,03198664 ! glial cell development GO:0021782 27 17 0,000 0,01902447 0,0319643 ! limbic system development GO:0021761 36 17 0,000 0,01902447 0,031942 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01902447 0,03191972 ! adult walking behavior GO:0007628 33 17 0,000 0,01902447 0,03189748 ! heart looping GO:0001947 30 17 0,000 0,01902447 0,03187526 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01902447 0,03185308 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01902447 0,03183093 ! myoblast differentiation GO:0045445 45 17 0,000 0,01902447 0,03180881 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01902447 0,03178672 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01902447 0,03176466 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01902447 0,03174263 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01902447 0,03172064 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01902447 0,03169867 ! glycine metabolic process GO:0006544 28 17 0,000 0,01902447 0,03167673 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01902447 0,03165483 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01902447 0,03163295 ! NAD metabolic process GO:0019674 29 17 0,000 0,01902447 0,0316111 ! DNA integration GO:0015074 29 17 0,000 0,01902447 0,03158929 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01902447 0,0315675 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01902447 0,03154575 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01902447 0,03152402 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01902447 0,03150233 ! genitalia development GO:0048806 30 17 0,000 0,01902447 0,03148066 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01902447 0,03145902 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01902447 0,03143742 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01902447 0,03141584 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01902447 0,03139429 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01902447 0,03137278 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01902447 0,03135129 ! steroid catabolic process GO:0006706 31 17 0,000 0,01902447 0,03132983 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01902447 0,0313084 ! gas transport GO:0015669 25 17 0,000 0,01902447 0,031287 ! organic cation transport GO:0015695 31 17 0,000 0,01902447 0,03126563 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01902447 0,03124429 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01902447 0,03122297 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01902447 0,03120169 ! microspike assembly GO:0030035 36 17 0,000 0,01902447 0,03118044 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01902447 0,03115921 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01902447 0,03113801 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02013255 0,03292924 ! neuron maturation GO:0042551 42 18 0,000 0,02013255 0,03290687 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02013255 0,03288453 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02013255 0,03286222 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02013255 0,03283994 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02013255 0,03281769 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02013255 0,03279547 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02013255 0,03277329 ! memory GO:0007613 31 18 0,000 0,02013255 0,03275113 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02013255 0,032729 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02013255 0,0327069 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02013255 0,03268483 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02013255 0,03266279 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02013255 0,03264078 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02013255 0,0326188 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02013255 0,03259685 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02013255 0,03257493 ! response to retinoic acid GO:0032526 26 18 0,000 0,02013255 0,03255304 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02013255 0,03253117 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02013255 0,03250934 ! response to fungus GO:0009620 21 18 0,000 0,02013255 0,03248754 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02013255 0,03246576 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02013255 0,03244402 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02013255 0,0324223 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02013255 0,03240061 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02013255 0,03237895 ! vitamin transport GO:0051180 27 18 0,000 0,02013255 0,03235733 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02013255 0,03233573 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02013255 0,03231415 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02013255 0,03229261 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02013255 0,0322711 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02013255 0,03224961 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02013255 0,03222815 ! nerve development GO:0021675 28 18 0,000 0,02013255 0,03220673 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02013255 0,03218533 ! protein secretion GO:0009306 39 19 0,000 0,02123941 0,03393229 ! positive regulation of translation GO:0045727 30 19 0,000 0,02123941 0,03390977 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02123941 0,03388729 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02123941 0,03386483 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02123941 0,0338424 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02123941 0,03382001 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02123941 0,03379764 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02123941 0,0337753 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02123941 0,03375299 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02123941 0,03373071 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02123941 0,03370846 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02123941 0,03368624 ! cerebral cortex development GO:0021987 36 19 0,000 0,02123941 0,03366405 ! pigmentation during development GO:0048066 41 19 0,000 0,02123941 0,03364189 ! response to vitamin A GO:0033189 27 19 0,000 0,02123941 0,03361976 ! heme metabolic process GO:0042168 36 19 0,000 0,02123941 0,03359765 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02123941 0,03357558 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02123941 0,03355353 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02123941 0,03353152 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02123941 0,03350953 ! peptide cross-linking GO:0018149 37 19 0,000 0,02123941 0,03348757 ! protein export from nucleus GO:0006611 36 19 0,000 0,02123941 0,03346564 ! heart process GO:0003015 30 19 0,000 0,02123941 0,03344374 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02123941 0,03342186 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02123941 0,03340002 ! cellular pigmentation GO:0033059 36 19 0,000 0,02123941 0,0333782 ! G1 phase GO:0051318 40 19 0,000 0,02123941 0,03335642 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02123941 0,03333466 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02123941 0,03331293 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02123941 0,03329123 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02123941 0,03326955 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02123941 0,03324791 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02123941 0,03322629 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02123941 0,0332047 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02123941 0,03318314 ! cilium assembly GO:0042384 37 19 0,000 0,02123941 0,0331616 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02123941 0,0331401 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02234506 0,03484266 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02234506 0,03482009 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02234506 0,03479756 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02234506 0,03477505 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02234506 0,03475257 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02234506 0,03473012 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02234506 0,0347077 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02234506 0,03468531 ! response to vitamin GO:0033273 31 20 0,000 0,02234506 0,03466294 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02234506 0,03464061 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02234506 0,0346183 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02234506 0,03459603 ! response to alkaloid GO:0043279 38 20 0,000 0,02234506 0,03457378 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02234506 0,03455156 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02234506 0,03452937 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02234506 0,0345072 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02234506 0,03448507 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02234506 0,03446296 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02234506 0,03444089 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02234506 0,03441884 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02234506 0,03439682 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02234506 0,03437482 ! body fluid secretion GO:0007589 31 20 0,000 0,02234506 0,03435286 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02234506 0,03433092 ! peptide secretion GO:0002790 35 20 0,000 0,02234506 0,03430901 ! stem cell differentiation GO:0048863 53 20 0,000 0,02234506 0,03428713 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02234506 0,03426528 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02234506 0,03424346 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02234506 0,03422166 ! sensory perception of pain GO:0019233 30 20 0,000 0,02234506 0,03419989 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02234506 0,03417815 ! diencephalon development GO:0021536 34 20 0,000 0,02234506 0,03415643 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02234506 0,03413475 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02234506 0,03411309 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02234506 0,03409146 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02234506 0,03406985 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02234506 0,03404827 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02234506 0,03402672 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02234506 0,0340052 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02234506 0,03398371 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02234506 0,03396224 ! regulation of glucose import GO:0046324 29 20 0,000 0,02234506 0,0339408 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02234506 0,03391938 ! actin filament-based movement GO:0030048 43 20 0,000 0,02234506 0,033898 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02234506 0,03387664 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02234506 0,03385531 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02234506 0,033834 ! negative regulation of translation GO:0017148 29 20 0,000 0,02234506 0,03381272 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02234506 0,03379147 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02234506 0,03377024 ! regulation of cell killing GO:0031341 42 21 0,000 0,0234495 0,03541714 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0234495 0,03539492 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0234495 0,03537273 ! hormone secretion GO:0046879 38 21 0,000 0,0234495 0,03535057 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0234495 0,03532843 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0234495 0,03530632 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0234495 0,03528424 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0234495 0,03526219 ! axis specification GO:0009798 38 21 0,000 0,0234495 0,03524016 ! ovarian follicle development GO:0001541 35 21 0,000 0,0234495 0,03521817 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0234495 0,0351962 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0234495 0,03517425 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0234495 0,03515234 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,0234495 0,03513045 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0234495 0,03510859 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0234495 0,03508676 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0234495 0,03506495 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0234495 0,03504317 ! cytolysis GO:0019835 24 21 0,000 0,0234495 0,03502142 ! vasodilation GO:0042311 39 21 0,000 0,0234495 0,03499969 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0234495 0,03497799 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0234495 0,03495632 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0234495 0,03493468 ! oogenesis GO:0048477 36 21 0,000 0,0234495 0,03491306 ! DNA modification GO:0006304 34 21 0,000 0,0234495 0,03489147 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0234495 0,0348699 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0234495 0,03484836 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0234495 0,03482685 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0234495 0,03480537 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,0234495 0,03478391 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0234495 0,03476248 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0234495 0,03474107 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0234495 0,03471969 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0234495 0,03469834 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0234495 0,03467701 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0234495 0,03465571 ! collagen catabolic process GO:0030574 28 21 0,000 0,0234495 0,03463444 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0234495 0,03461319 ! gut development GO:0048565 39 21 0,000 0,0234495 0,03459197 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02455273 0,03619722 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02455273 0,03617506 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02455273 0,03615292 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02455273 0,03613081 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02455273 0,03610872 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02455273 0,03608666 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02455273 0,03606463 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02455273 0,03604263 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02455273 0,03602065 ! regeneration GO:0031099 41 22 0,000 0,02455273 0,0359987 ! keratinization GO:0031424 28 22 0,000 0,02455273 0,03597678 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02455273 0,03595488 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02455273 0,03593301 ! sensory perception of taste GO:0050909 28 22 0,000 0,02455273 0,03591117 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02455273 0,03588935 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02455273 0,03586756 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02455273 0,03584579 ! vacuolar transport GO:0007034 36 22 0,000 0,02455273 0,03582405 ! lysosome organization GO:0007040 41 22 0,000 0,02455273 0,03580234 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02455273 0,03578066 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02455273 0,035759 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02455273 0,03573737 ! fucose metabolic process GO:0006004 39 22 0,000 0,02455273 0,03571576 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02455273 0,03569418 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02455273 0,03567262 ! ureteric bud development GO:0001657 43 22 0,000 0,02455273 0,0356511 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02455273 0,03562959 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02455273 0,03560812 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02455273 0,03558667 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02455273 0,03556524 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02455273 0,03554384 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02455273 0,03552247 ! sarcomere organization GO:0045214 30 22 0,000 0,02455273 0,03550112 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,02455273 0,0354798 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02455273 0,0354585 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02455273 0,03543723 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02455273 0,03541599 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02455273 0,03539477 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02455273 0,03537357 ! protein stabilization GO:0050821 39 22 0,000 0,02455273 0,0353524 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02565475 0,03691706 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02565475 0,03689499 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02565475 0,03687295 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02565475 0,03685094 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02565475 0,03682895 ! gluconeogenesis GO:0006094 33 23 0,000 0,02565475 0,03680699 ! viral genome replication GO:0019079 41 23 0,000 0,02565475 0,03678505 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02565475 0,03676314 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02565475 0,03674126 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02565475 0,03671941 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02565475 0,03669757 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02565475 0,03667577 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02565475 0,03665399 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02565475 0,03663224 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02565475 0,03661051 ! response to ethanol GO:0045471 46 23 0,000 0,02565475 0,03658881 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02565475 0,03656713 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,02565475 0,03654548 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02565475 0,03652386 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02565475 0,03650226 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02565475 0,03648069 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02565475 0,03645914 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02565475 0,03643761 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02565475 0,03641612 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02565475 0,03639465 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02565475 0,0363732 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02565475 0,03635178 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02565475 0,03633038 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02565475 0,03630901 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02565475 0,03628767 ! fatty acid transport GO:0015908 44 23 0,000 0,02565475 0,03626635 ! platelet activation GO:0030168 37 23 0,000 0,02565475 0,03624505 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02565475 0,03622378 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02565475 0,03620253 ! hormone transport GO:0009914 40 23 0,000 0,02565475 0,03618131 ! cell-cell recognition GO:0009988 25 23 0,000 0,02565475 0,03616012 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02565475 0,03613895 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02565475 0,0361178 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02565475 0,03609668 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02565475 0,03607558 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02675556 0,03760156 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,02675556 0,03757961 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02675556 0,03755768 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02675556 0,03753578 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02675556 0,03751391 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02675556 0,03749206 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02675556 0,03747024 ! vesicle docking GO:0048278 47 24 0,000 0,02675556 0,03744844 ! spinal cord development GO:0021510 47 24 0,000 0,02675556 0,03742667 ! vacuole organization GO:0007033 43 24 0,000 0,02675556 0,03740492 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02675556 0,0373832 ! digestive system process GO:0022600 39 24 0,000 0,02675556 0,0373615 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02675556 0,03733983 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02675556 0,03731818 ! regulation of behavior GO:0050795 43 24 0,000 0,02675556 0,03729656 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02675556 0,03727497 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02675556 0,03725339 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02675556 0,03723185 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,02675556 0,03721033 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02675556 0,03718883 ! membrane depolarization GO:0051899 39 24 0,000 0,02675556 0,03716736 ! pallium development GO:0021543 49 24 0,000 0,02675556 0,03714591 ! pentose metabolic process GO:0019321 35 24 0,000 0,02675556 0,03712449 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02675556 0,03710309 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02675556 0,03708172 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02675556 0,03706037 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02675556 0,03703905 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02675556 0,03701775 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02675556 0,03699647 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02675556 0,03697522 ! regulation of amine transport GO:0051952 40 24 0,000 0,02675556 0,036954 ! protein tetramerization GO:0051262 52 24 0,000 0,02675556 0,0369328 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02785516 0,03842862 ! myelination GO:0042552 45 25 0,000 0,02785516 0,03840659 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02785516 0,0383846 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02785516 0,03836263 ! phototransduction GO:0007602 33 25 0,000 0,02785516 0,03834068 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02785516 0,03831876 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02785516 0,03829686 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02785516 0,03827499 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02785516 0,03825314 ! receptor metabolic process GO:0043112 46 25 0,000 0,02785516 0,03823132 ! chromosome condensation GO:0030261 45 25 0,000 0,02785516 0,03820953 ! response to starvation GO:0042594 42 25 0,000 0,02785516 0,03818775 ! neural crest cell development GO:0014032 54 25 0,000 0,02785516 0,03816601 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02785516 0,03814428 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02785516 0,03812259 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02785516 0,03810091 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02785516 0,03807927 ! interaction with host GO:0051701 62 25 0,000 0,02785516 0,03805764 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02785516 0,03803604 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02785516 0,03801447 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02785516 0,03799292 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02785516 0,03797139 ! immunoglobulin production GO:0002377 55 25 0,000 0,02785516 0,03794989 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02785516 0,03792841 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02785516 0,03790696 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02785516 0,03788553 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02785516 0,03786413 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02785516 0,03784275 ! telomere organization GO:0032200 43 25 0,000 0,02785516 0,03782139 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02785516 0,03780006 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02785516 0,03777875 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02895355 0,03924634 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02895355 0,03922424 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02895355 0,03920217 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02895355 0,03918012 ! initiation of viral infection GO:0019059 57 26 0,000 0,02895355 0,03915809 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02895355 0,03913609 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02895355 0,03911412 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02895355 0,03909217 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02895355 0,03907025 ! molting cycle process GO:0022404 50 26 0,000 0,02895355 0,03904834 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02895355 0,03902647 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02895355 0,03900462 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02895355 0,03898279 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02895355 0,03896099 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02895355 0,03893921 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02895355 0,03891746 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02895355 0,03889573 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02895355 0,03887402 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,02895355 0,03885234 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02895355 0,03883068 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02895355 0,03880905 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02895355 0,03878744 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02895355 0,03876586 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02895355 0,0387443 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02895355 0,03872276 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02895355 0,03870125 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02895355 0,03867976 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02895355 0,03865829 ! blastocyst development GO:0001824 49 26 0,000 0,02895355 0,03863685 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02895355 0,03861544 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02895355 0,03859404 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02895355 0,03857267 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,03005074 0,04001222 ! neuron fate commitment GO:0048663 48 27 0,000 0,03005074 0,03999009 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03005074 0,03996799 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03005074 0,03994591 ! iron ion transport GO:0006826 59 27 0,000 0,03005074 0,03992385 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03005074 0,03990182 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03005074 0,03987981 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03005074 0,03985782 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03005074 0,03983586 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03005074 0,03981393 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03005074 0,03979201 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03005074 0,03977013 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03005074 0,03974826 ! autophagy GO:0006914 41 27 0,000 0,03005074 0,03972642 ! male gonad development GO:0008584 44 27 0,000 0,03005074 0,03970461 ! response to toxin GO:0009636 47 27 0,000 0,03005074 0,03968282 ! primary neural tube formation GO:0014020 51 27 0,000 0,03005074 0,03966105 ! base-excision repair GO:0006284 41 27 0,000 0,03005074 0,0396393 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03005074 0,03961758 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03005074 0,03959589 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03005074 0,03957421 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03005074 0,03955257 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03005074 0,03953094 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03005074 0,03950934 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03005074 0,03948776 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03005074 0,03946621 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03114673 0,04088327 ! circadian rhythm GO:0007623 50 28 0,000 0,03114673 0,04086098 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03114673 0,04083871 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03114673 0,04081647 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03114673 0,04079425 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03114673 0,04077205 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03114673 0,04074988 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03114673 0,04072774 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03114673 0,04070561 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03114673 0,04068352 ! synaptogenesis GO:0007416 42 28 0,000 0,03114673 0,04066144 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03114673 0,04063939 ! lipid oxidation GO:0034440 43 28 0,000 0,03114673 0,04061736 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03114673 0,04059536 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03114673 0,04057338 ! translational initiation GO:0006413 65 29 0,000 0,03224152 0,04197678 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03224152 0,04195408 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03224152 0,0419314 ! regulation of pH GO:0006885 43 29 0,000 0,03224152 0,04190875 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03224152 0,04188612 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03224152 0,04186351 ! catechol metabolic process GO:0009712 54 29 0,000 0,03224152 0,04184093 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03224152 0,04181838 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03224152 0,04179585 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03224152 0,04177334 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03224152 0,04175086 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03224152 0,0417284 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03224152 0,04170596 ! cell fate determination GO:0001709 60 29 0,000 0,03224152 0,04168355 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03224152 0,04166117 ! detection of light stimulus GO:0009583 38 29 0,000 0,03224152 0,0416388 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,03224152 0,04161646 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03224152 0,04159415 ! tissue homeostasis GO:0001894 48 29 0,000 0,03224152 0,04157186 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03224152 0,04154959 ! phenol metabolic process GO:0018958 55 30 0,000 0,0333351 0,0429359 ! zinc ion transport GO:0006829 45 30 0,000 0,0333351 0,04291292 ! membrane docking GO:0022406 61 30 0,000 0,0333351 0,04288998 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0333351 0,04286705 ! cell junction assembly GO:0034329 78 30 0,000 0,0333351 0,04284415 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0333351 0,04282128 ! acute-phase response GO:0006953 49 30 0,000 0,0333351 0,04279843 ! myofibril assembly GO:0030239 47 30 0,000 0,0333351 0,0427756 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0333351 0,0427528 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0333351 0,04273002 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0333351 0,04270727 ! phospholipid transport GO:0015914 51 30 0,000 0,0333351 0,04268454 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0333351 0,04266184 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0333351 0,04263916 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0333351 0,0426165 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0333351 0,04259387 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0333351 0,04257126 ! regulation of B cell activation GO:0050864 50 30 0,000 0,0333351 0,04254868 ! response to heat GO:0009408 50 30 0,000 0,0333351 0,04252612 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03442749 0,04389642 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03442749 0,04387317 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03442749 0,04384994 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03442749 0,04382674 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,03442749 0,04380356 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03442749 0,04378041 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03442749 0,04375728 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03442749 0,04373418 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03442749 0,0437111 ! ovulation cycle process GO:0022602 49 31 0,000 0,03442749 0,04368805 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03442749 0,04366502 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03442749 0,04364201 ! peptide transport GO:0015833 55 31 0,000 0,03442749 0,04361903 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03442749 0,04359607 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03442749 0,04357314 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03442749 0,04355023 ! mesoderm formation GO:0001707 69 31 0,000 0,03442749 0,04352734 ! natural killer cell activation GO:0030101 45 31 0,000 0,03442749 0,04350448 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03442749 0,04348165 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03442749 0,04345883 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03442749 0,04343604 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03442749 0,04341328 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03442749 0,04339054 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03551868 0,04474237 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03551868 0,04471896 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03551868 0,04469557 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03551868 0,04467221 ! cholesterol transport GO:0030301 56 32 0,000 0,03551868 0,04464887 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03551868 0,04462555 ! spliceosome assembly GO:0000245 67 32 0,000 0,03551868 0,04460226 ! spindle organization GO:0007051 46 32 0,000 0,03551868 0,04457899 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03551868 0,04455575 ! metanephros development GO:0001656 74 32 0,000 0,03551868 0,04453253 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03551868 0,04450934 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03551868 0,04448617 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03551868 0,04446302 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03551868 0,0444399 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03551868 0,04441681 ! muscle cell development GO:0055001 49 32 0,000 0,03551868 0,04439373 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03551868 0,04437068 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03551868 0,04434766 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03551868 0,04432465 ! ovulation cycle GO:0042698 51 32 0,000 0,03551868 0,04430168 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03551868 0,04427872 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03551868 0,04425579 ! hindbrain development GO:0030902 61 32 0,000 0,03551868 0,04423288 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03551868 0,04421 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03551868 0,04418714 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03551868 0,04416431 ! gene silencing GO:0016458 65 32 0,000 0,03551868 0,04414149 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03660867 0,04547261 ! post-embryonic development GO:0009791 69 33 0,000 0,03660867 0,04544915 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03660867 0,04542571 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03660867 0,04540229 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03660867 0,0453789 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03660867 0,04535554 ! cell fate specification GO:0001708 52 33 0,000 0,03660867 0,04533219 ! sterol transport GO:0015918 57 33 0,000 0,03660867 0,04530887 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03660867 0,04528558 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03660867 0,04526231 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03660867 0,04523906 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03660867 0,04521584 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03660867 0,04519264 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03769746 0,04651287 ! glial cell differentiation GO:0010001 63 34 0,000 0,03769746 0,04648903 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03769746 0,04646521 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03769746 0,04644142 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03769746 0,04641765 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03769746 0,04639391 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03769746 0,04637019 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03769746 0,0463465 ! mismatch repair GO:0006298 46 34 0,000 0,03769746 0,04632282 ! spermatid development GO:0007286 63 34 0,000 0,03769746 0,04629918 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03769746 0,04627556 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03769746 0,04625196 ! placenta development GO:0001890 53 34 0,000 0,03769746 0,04622838 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03769746 0,04620483 ! regulation of muscle development GO:0048634 70 35 0,000 0,03878506 0,04751368 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03878506 0,0474895 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03878506 0,04746534 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03878506 0,04744121 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03878506 0,0474171 ! odontogenesis GO:0042476 66 35 0,000 0,03878506 0,04739302 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03878506 0,04736896 ! female gonad development GO:0008585 58 35 0,000 0,03878506 0,04734493 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03878506 0,04732092 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03878506 0,04729694 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03878506 0,04727298 ! cytokine production GO:0001816 59 35 0,000 0,03878506 0,04724904 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,03878506 0,04722513 ! neural tube formation GO:0001841 67 35 0,000 0,03878506 0,04720124 ! vesicle localization GO:0051648 64 35 0,000 0,03878506 0,04717738 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03987147 0,04847436 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03987147 0,04844988 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03987147 0,04842542 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03987147 0,04840099 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03987147 0,04837658 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03987147 0,04835219 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03987147 0,04832784 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03987147 0,0483035 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03987147 0,04827919 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03987147 0,04825491 ! aerobic respiration GO:0009060 55 36 0,000 0,03987147 0,04823065 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03987147 0,04820641 ! embryonic organ development GO:0048568 57 36 0,000 0,03987147 0,0481822 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03987147 0,04815801 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04095668 0,04944395 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04095668 0,04941915 ! meiosis I GO:0007127 65 37 0,000 0,04095668 0,04939438 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04095668 0,04936963 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04095668 0,04934491 ! organic anion transport GO:0015711 68 37 0,000 0,04095668 0,04932021 ! tissue remodeling GO:0048771 76 37 0,000 0,04095668 0,04929554 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04095668 0,04927089 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04095668 0,04924627 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04095668 0,04922167 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04095668 0,0491971 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04095668 0,04917255 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04095668 0,04914802 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04095668 0,04912352 ! pigment metabolic process GO:0042440 80 37 0,000 0,04095668 0,04909904 ! spermatid differentiation GO:0048515 66 37 0,000 0,04095668 0,04907459 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04095668 0,04905017 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04204071 0,05032336 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04204071 0,05029833 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04204071 0,05027333 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04204071 0,05024836 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04204071 0,05022341 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04204071 0,05019848 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04204071 0,05017358 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04204071 0,05014871 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04204071 0,05012386 ! lipid homeostasis GO:0055088 67 38 0,000 0,04204071 0,05009903 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04204071 0,05007423 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04204071 0,05004945 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04204071 0,0500247 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04204071 0,04999997 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,04204071 0,04997527 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04204071 0,04995059 ! glucan metabolic process GO:0044042 62 38 0,000 0,04204071 0,04992594 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 0,000 0,04312355 0,05118661 ! ear morphogenesis GO:0042471 60 39 0,000 0,04312355 0,05116137 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04312355 0,05113615 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04312355 0,05111096 ! segmentation GO:0035282 67 39 0,000 0,04312355 0,0510858 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04312355 0,05106065 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04312355 0,05103554 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04312355 0,05101045 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04312355 0,05098538 ! RNA modification GO:0009451 57 39 0,000 0,04312355 0,05096034 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04312355 0,05093532 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04420519 0,05218729 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04420519 0,05216169 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04420519 0,05213612 ! feeding behavior GO:0007631 59 40 0,000 0,04420519 0,05211058 ! negative regulation of binding GO:0051100 72 40 0,000 0,04420519 0,05208506 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,04420519 0,05205957 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04420519 0,0520341 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04420519 0,05200865 ! maintenance of protein location GO:0045185 91 40 0,000 0,04420519 0,05198323 ! cytokinesis GO:0000910 72 40 0,000 0,04420519 0,05195784 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04528565 0,0532018 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04528565 0,05317583 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04528565 0,05314989 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04528565 0,05312398 ! gliogenesis GO:0042063 88 41 0,000 0,04528565 0,05309809 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04528565 0,05307223 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04528565 0,05304639 ! T cell differentiation GO:0030217 81 41 0,000 0,04528565 0,05302058 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04528565 0,05299479 ! female gamete generation GO:0007292 61 41 0,000 0,04528565 0,05296902 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04528565 0,05294329 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,04636493 0,05417874 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,04636493 0,05415244 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,04636493 0,05412616 ! regulation of tube size GO:0035150 71 42 0,000 0,04636493 0,05409991 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,04636493 0,05407369 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,04636493 0,05404749 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,04636493 0,05402132 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,04636493 0,05399517 ! neuron migration GO:0001764 79 42 0,000 0,04636493 0,05396905 ! regulation of protein secretion GO:0050708 71 42 0,000 0,04636493 0,05394295 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,04636493 0,05391688 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,04744302 0,05514392 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04744302 0,05511729 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04744302 0,05509069 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04744302 0,05506411 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04744302 0,05503756 ! glucose transport GO:0015758 65 43 0,000 0,04744302 0,05501104 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04744302 0,05498454 ! neural tube development GO:0021915 77 43 0,000 0,04744302 0,05495807 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04744302 0,05493162 ! striated muscle contraction GO:0006941 77 43 0,000 0,04744302 0,0549052 ! phagocytosis GO:0006909 90 43 0,000 0,04744302 0,0548788 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04744302 0,05485243 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04851993 0,05607058 ! hexose transport GO:0008645 67 44 0,000 0,04851993 0,05604366 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04851993 0,05601677 ! male sex differentiation GO:0046661 76 44 0,000 0,04851993 0,0559899 ! double-strand break repair GO:0006302 81 44 0,000 0,04851993 0,05596306 ! biopolymer methylation GO:0043414 84 44 0,000 0,04851993 0,05593625 ! B cell differentiation GO:0030183 107 44 0,000 0,04851993 0,05590946 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04851993 0,05588269 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04851993 0,05585596 ! developmental growth GO:0048589 82 44 0,000 0,04851993 0,05582924 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04851993 0,05580256 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,04959566 0,05701249 ! glycolysis GO:0006096 65 45 0,000 0,04959566 0,05698527 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,04959566 0,05695807 ! leukocyte migration GO:0050900 68 45 0,000 0,04959566 0,05693089 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,04959566 0,05690374 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,04959566 0,05687662 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,04959566 0,05684952 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,04959566 0,05682245 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,04959566 0,05679541 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,04959566 0,05676839 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,04959566 0,05674139 ! cell growth GO:0016049 84 45 0,000 0,04959566 0,05671442 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0506702 0,05791568 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0506702 0,05788818 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0506702 0,0578607 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0506702 0,05783326 ! pigmentation GO:0043473 100 46 0,000 0,0506702 0,05780583 ! response to insulin stimulus GO:0032868 95 46 0,000 0,0506702 0,05777844 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0506702 0,05775107 ! positive regulation of defense response GO:0031349 76 47 0,000 0,05174357 0,05894651 ! endosome transport GO:0016197 108 47 0,000 0,05174357 0,05891861 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,05174357 0,05889074 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,05174357 0,0588629 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,05174357 0,05883508 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,05174357 0,05880729 ! JNK cascade GO:0007254 91 47 0,000 0,05174357 0,05877952 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,05174357 0,05875178 ! methylation GO:0032259 90 47 0,000 0,05174357 0,05872407 ! protein homooligomerization GO:0051260 76 47 0,000 0,05174357 0,05869638 ! mitochondrial transport GO:0006839 82 48 0,000 0,05281576 0,05988441 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05281576 0,0598562 ! cellular component disassembly GO:0022411 86 48 0,000 0,05281576 0,05982802 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05281576 0,05979986 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,05281576 0,05977174 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,05281576 0,05974363 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05281576 0,05971556 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05281576 0,05968751 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05281576 0,05965949 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,05281576 0,05963149 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,05388677 0,06081218 ! regulation of action potential GO:0001508 95 49 0,000 0,05388677 0,06078367 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,05388677 0,06075519 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,05388677 0,06072673 ! regulation of ion transport GO:0043269 77 49 0,000 0,05388677 0,0606983 ! peptide metabolic process GO:0006518 76 49 0,000 0,05388677 0,0606699 ! response to temperature stimulus GO:0009266 76 49 0,000 0,05388677 0,06064152 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,05388677 0,06061317 ! endocrine system development GO:0035270 104 49 0,000 0,05388677 0,06058484 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,05388677 0,06055655 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,05388677 0,06052828 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,05388677 0,06050003 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,05388677 0,06047181 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,05495661 0,06164363 ! neuromuscular process GO:0050905 99 50 0,000 0,05495661 0,06161491 ! regulation of ossification GO:0030278 117 50 0,000 0,05495661 0,06158621 ! inner ear development GO:0048839 79 50 0,000 0,05495661 0,06155754 ! histone modification GO:0016570 91 50 0,000 0,05495661 0,06152889 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05495661 0,06150028 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05495661 0,06147168 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05495661 0,06144312 ! positive regulation of binding GO:0051099 78 51 0,000 0,05602527 0,06260882 ! viral infectious cycle GO:0019058 99 51 0,000 0,05602527 0,06257976 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,05602527 0,06255072 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,05602527 0,0625217 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,05602527 0,06249272 ! excretion GO:0007588 83 51 0,000 0,05602527 0,06246376 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,05602527 0,06243483 ! chromatin remodeling GO:0006338 109 51 0,000 0,05602527 0,06240592 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,05602527 0,06237705 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,05602527 0,06234819 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,05602527 0,06231937 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,05602527 0,06229057 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,05709276 0,06344812 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,05709276 0,06341883 ! membrane fusion GO:0006944 110 52 0,000 0,05709276 0,06338956 ! covalent chromatin modification GO:0016569 101 52 0,000 0,05709276 0,06336032 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,05709276 0,06333111 ! cartilage development GO:0051216 90 52 0,000 0,05709276 0,06330192 ! synapse organization GO:0050808 85 52 0,000 0,05709276 0,06327277 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,05815908 0,06442483 ! regulation of translational initiation GO:0006446 82 53 0,000 0,05815908 0,06439518 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,05815908 0,06436556 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,05815908 0,06433597 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,05815908 0,0643064 ! cell maturation GO:0048469 100 53 0,000 0,05815908 0,06427687 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,05815908 0,06424735 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05922422 0,06539398 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,05922422 0,06536398 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05922422 0,06533401 ! cell recognition GO:0008037 85 54 0,000 0,05922422 0,06530407 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05922422 0,06527416 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05922422 0,06524427 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05922422 0,06521441 ! chloride transport GO:0006821 90 55 0,000 0,0602882 0,06635563 ! glucose catabolic process GO:0006007 82 55 0,000 0,0602882 0,06632529 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,0602882 0,06629498 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,0602882 0,06626469 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,0602882 0,06623443 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,0602882 0,0662042 ! gastrulation GO:0007369 112 55 0,000 0,0602882 0,066174 ! heart morphogenesis GO:0003007 97 55 0,000 0,0602882 0,06614383 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,0602882 0,06611368 ! RNA elongation GO:0006354 79 55 0,000 0,0602882 0,06608356 ! nuclear export GO:0051168 97 55 0,000 0,0602882 0,06605347 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,0602882 0,0660234 ! regulation of actin filament length GO:0030832 105 56 0,000 0,06135101 0,06715675 ! sensory perception of smell GO:0007608 80 56 0,000 0,06135101 0,06712621 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,06135101 0,0670957 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,06135101 0,06706521 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,06135101 0,06703476 ! regulation of DNA replication GO:0006275 101 56 0,000 0,06135101 0,06700433 ! proton transport GO:0015992 94 56 0,000 0,06135101 0,06697393 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,06135101 0,06694355 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06241265 0,0680711 ! muscle fiber development GO:0048747 112 57 0,000 0,06241265 0,06804026 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06241265 0,06800944 ! lipid modification GO:0030258 97 57 0,000 0,06241265 0,06797865 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06241265 0,06794789 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,06241265 0,06791716 ! maintenance of location GO:0051235 118 57 0,000 0,06241265 0,06788646 ! hydrogen transport GO:0006818 97 58 0,000 0,06347313 0,06900875 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,06347313 0,06897758 ! regulation of endocytosis GO:0030100 91 58 0,000 0,06347313 0,06894644 ! adult behavior GO:0030534 99 58 0,000 0,06347313 0,06891532 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,06347313 0,06888424 ! positive regulation of secretion GO:0051047 95 59 0,000 0,06453245 0,07000228 ! regulation of cellular component size GO:0032535 109 59 0,000 0,06453245 0,06997074 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,06453245 0,06993922 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,06453245 0,06990773 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,06453245 0,06987627 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,06453245 0,06984483 ! establishment of organelle localization GO:0051656 109 59 0,000 0,06453245 0,06981343 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0655906 0,07092628 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0655906 0,07089442 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0655906 0,07086259 ! camera-type eye development GO:0043010 116 60 0,000 0,0655906 0,07083078 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0655906 0,070799 ! kidney development GO:0001822 122 60 0,000 0,0655906 0,07076725 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,06664759 0,07187543 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,06664759 0,07184323 ! mesoderm development GO:0007498 119 61 0,000 0,06664759 0,07181106 ! tRNA processing GO:0008033 89 61 0,000 0,06664759 0,07177891 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,06664759 0,0717468 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,06664759 0,07171471 ! ear development GO:0043583 103 62 0,000 0,06770342 0,07281825 ! viral reproductive process GO:0022415 126 62 0,000 0,06770342 0,07278571 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,06770342 0,0727532 ! gonad development GO:0008406 98 62 0,000 0,06770342 0,07272072 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,06770342 0,07268827 ! regulation of mitosis GO:0007088 105 63 0,000 0,06875808 0,07378767 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,06875808 0,07375477 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,06875808 0,0737219 ! detection of external stimulus GO:0009581 91 63 0,000 0,06875808 0,07368906 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,06875808 0,07365626 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,06875808 0,07362348 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,0698116 0,07471828 ! cell redox homeostasis GO:0045454 102 64 0,000 0,0698116 0,07468506 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,0698116 0,07465187 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,0698116 0,0746187 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,0698116 0,07458557 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,0698116 0,07455246 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,07086395 0,07564271 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,07086395 0,07560916 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,07086395 0,07557565 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,07086395 0,07554216 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,07086395 0,07550871 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,07191515 0,07659489 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,07191515 0,07656099 ! extracellular matrix organization GO:0030198 133 66 0,000 0,07191515 0,07652713 ! secondary metabolic process GO:0019748 116 66 0,000 0,07191515 0,0764933 ! developmental maturation GO:0021700 116 66 0,000 0,07191515 0,0764595 ! cell projection assembly GO:0030031 120 66 0,000 0,07191515 0,07642573 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,07296519 0,0775074 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,07296519 0,07747319 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,07296519 0,07743902 ! activation of MAPK activity GO:0000187 115 67 0,000 0,07296519 0,07740487 ! lung development GO:0030324 144 67 0,000 0,07296519 0,07737076 ! chromosome segregation GO:0007059 113 67 0,000 0,07296519 0,07733668 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,07296519 0,07730262 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,07296519 0,0772686 ! hexose catabolic process GO:0019320 104 67 0,000 0,07296519 0,0772346 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,07296519 0,07720064 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,07296519 0,07716671 ! adaptive immune response GO:0002250 119 67 0,000 0,07296519 0,0771328 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,07296519 0,07709893 ! amino acid transport GO:0006865 125 68 0,000 0,07401408 0,07817291 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,07401408 0,07813861 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,07401408 0,07810434 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,07401408 0,0780701 ! viral reproduction GO:0016032 134 68 0,000 0,07401408 0,07803588 ! regulation of lipase activity GO:0060191 130 68 0,000 0,07401408 0,0780017 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,07401408 0,07796755 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,07506182 0,07903665 ! negative regulation of cell size GO:0045792 134 69 0,000 0,07506182 0,07900208 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,07506182 0,07896753 ! urogenital system development GO:0001655 137 69 0,000 0,07506182 0,07893302 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,07506182 0,07889854 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,07506182 0,07886408 ! antigen processing and presentation GO:0019882 104 69 0,000 0,07506182 0,07882966 ! appendage morphogenesis GO:0035107 135 70 0,000 0,07610841 0,07989391 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,07610841 0,07985907 ! amine catabolic process GO:0009310 117 71 0,000 0,07715385 0,08092074 ! reproductive structure development GO:0048608 113 71 0,000 0,07715385 0,08088548 ! appendage development GO:0048736 136 71 0,000 0,07715385 0,08085025 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,07715385 0,08081505 ! B cell activation GO:0042113 160 71 0,000 0,07715385 0,08077988 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,07715385 0,08074474 ! regulation of immune effector process GO:0002697 137 71 0,000 0,07715385 0,08070964 ! acute inflammatory response GO:0002526 113 72 0,000 0,07819814 0,08176651 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,07819814 0,08173099 ! carbohydrate transport GO:0008643 110 72 0,000 0,07819814 0,0816955 ! respiratory system development GO:0060541 153 72 0,000 0,07819814 0,08166004 ! regulation of blood pressure GO:0008217 125 73 0,000 0,07924129 0,08271346 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,07924129 0,0826776 ! axon guidance GO:0007411 139 73 0,000 0,07924129 0,08264176 ! fertilization GO:0009566 90 73 0,000 0,07924129 0,08260595 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,08028329 0,08365595 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,08028329 0,08361973 ! neurotransmitter transport GO:0006836 123 74 0,000 0,08028329 0,08358355 ! meiosis GO:0007126 121 74 0,000 0,08028329 0,0835474 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,08028329 0,08351128 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,08028329 0,08347519 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,08028329 0,08343913 ! organelle localization GO:0051640 136 74 0,000 0,08028329 0,0834031 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,08132414 0,08444794 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,08132414 0,08441151 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,08132414 0,08437511 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,08132414 0,08433874 ! meiotic cell cycle GO:0051321 122 75 0,000 0,08132414 0,0843024 ! rhythmic process GO:0048511 128 75 0,000 0,08132414 0,0842661 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,08132414 0,08422982 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,08236385 0,08526997 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,08236385 0,0852333 ! defense response to bacterium GO:0042742 89 76 0,000 0,08236385 0,08519666 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,08236385 0,08516004 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,08236385 0,08512346 ! regulation of catabolic process GO:0009894 161 76 0,000 0,08236385 0,08508691 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,08340242 0,08612284 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,08340242 0,08608589 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,08340242 0,08604898 ! blood coagulation GO:0007596 146 78 0,000 0,08443984 0,08708198 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,08443984 0,08704467 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,08443984 0,08700739 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,08443984 0,08697015 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,08547613 0,08799982 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,08651128 0,08902744 ! protein import into nucleus GO:0006606 158 80 0,000 0,08651128 0,08898937 ! inorganic anion transport GO:0015698 138 80 0,000 0,08651128 0,08895134 ! T cell activation GO:0042110 168 81 0,000 0,08754529 0,08997607 ! response to hypoxia GO:0001666 171 81 0,000 0,08754529 0,08993765 ! digestion GO:0007586 112 81 0,000 0,08754529 0,08989926 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,08754529 0,08986091 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,08754529 0,08982259 ! nuclear import GO:0051170 161 81 0,000 0,08754529 0,0897843 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,08754529 0,08974605 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,08857817 0,09076622 ! response to drug GO:0042493 143 82 0,000 0,08857817 0,09072758 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,08857817 0,09068897 ! response to oxygen levels GO:0070482 176 83 0,000 0,08960991 0,09170627 ! hemostasis GO:0007599 158 84 0,000 0,09064052 0,09272155 ! negative regulation of transport GO:0051051 153 84 0,000 0,09064052 0,09268214 ! negative regulation of growth GO:0045926 155 84 0,000 0,09064052 0,09264277 ! nucleosome assembly GO:0006334 122 85 0,000 0,09166999 0,0936552 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,09166999 0,09361545 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,09166999 0,09357573 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,09269834 0,09458533 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,09269834 0,09454523 ! chromatin assembly GO:0031497 124 86 0,000 0,09269834 0,09450517 ! tube morphogenesis GO:0035239 176 86 0,000 0,09269834 0,09446514 ! amine transport GO:0015837 155 86 0,000 0,09269834 0,09442515 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,09372555 0,09543109 ! protein localization in nucleus GO:0034504 176 87 0,000 0,09372555 0,09539073 ! regulation of protein transport GO:0051223 154 87 0,000 0,09372555 0,09535039 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,09475164 0,09635352 ! regulation of DNA binding GO:0051101 155 88 0,000 0,09475164 0,09631282 ! gland development GO:0048732 206 88 0,000 0,09475164 0,09627214 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,09475164 0,0962315 ! cellular defense response GO:0006968 114 89 0,000 0,09577659 0,09723143 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,09577659 0,09719042 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,09577659 0,09714944 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,09680042 0,09814657 ! sex differentiation GO:0007548 145 90 0,000 0,09680042 0,09810523 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,09680042 0,09806392 ! sterol metabolic process GO:0016125 152 91 0,000 0,09782313 0,09905827 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,09782313 0,0990166 ! regulation of defense response GO:0031347 149 92 0,000 0,09884471 0,10000857 ! nucleosome organization GO:0034728 138 92 0,000 0,09884471 0,09996653 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,09884471 0,09992453 ! vitamin metabolic process GO:0006766 139 92 0,000 0,09884471 0,09988256 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,09986517 0,10087137 ! regulation of membrane potential GO:0042391 164 93 0,000 0,09986517 0,10082904 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,09986517 0,10078674 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,10088451 0,1017728 ! female pregnancy GO:0007565 164 94 0,000 0,10088451 0,10173014 ! transcription initiation GO:0006352 153 94 0,000 0,10088451 0,10168753 ! regulation of T cell activation GO:0050863 158 94 0,000 0,10088451 0,10164494 ! forebrain development GO:0030900 188 95 0,000 0,10190272 0,10262786 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,10190272 0,10258492 ! leukocyte differentiation GO:0002521 202 96 0,000 0,10291982 0,10356549 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,10291982 0,1035222 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,10291982 0,10347894 ! positive regulation of immune response GO:0050778 156 96 0,000 0,10291982 0,10343571 ! detection of stimulus GO:0051606 151 96 0,000 0,10291982 0,10339252 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,1039358 0,10436959 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,1039358 0,10432605 ! protein ubiquitination GO:0016567 217 97 0,000 0,1039358 0,10428254 ! hormone metabolic process GO:0042445 157 97 0,000 0,1039358 0,10423907 ! regulation of protein localization GO:0032880 176 97 0,000 0,1039358 0,10419564 ! response to virus GO:0009615 160 98 0,000 0,10495066 0,10516922 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,10495066 0,10512544 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,10495066 0,10508169 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,10596441 0,10605257 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,10596441 0,10600847 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,10697704 0,10697704