pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/7013-8-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,073E-06 2,468E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 4,289E-06 4,933E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 8,787E-06 6,736E-03 ! interphase GO:0051325 159 88 3,000 9,628E-06 5,536E-03 ! skeletal myofibril assembly GO:0014866 7 5 1,000 2,291E-05 0,01053646 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 3,433E-05 0,01315802 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 3,891E-05 0,01278403 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 3,891E-05 0,01118603 ! response to UV GO:0009411 75 46 2,000 4,771E-05 0,0121928 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,801E-05 0,0110422 ! negative regulation of telomere maintenance GO:0032205 9 7 1,000 4,801E-05 0,01003837 ! skeletal muscle fiber development GO:0048741 73 50 2,000 6,135E-05 0,01175875 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,395E-05 0,01131454 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,395E-05 0,01050636 ! induction of an organ GO:0001759 11 8 1,000 6,395E-05 9,806E-03 ! regulation of telomere maintenance GO:0032204 10 8 1,000 6,395E-05 9,193E-03 ! muscle fiber development GO:0048747 74 51 2,000 6,512E-05 8,81E-03 ! thymus development GO:0048538 15 9 1,000 8,215E-05 0,01049635 ! thyroid gland development GO:0030878 19 10 1,000 1,026E-04 0,01241804 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,026E-04 0,01179714 ! developmental induction GO:0031128 13 10 1,000 1,026E-04 0,01123537 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,114E-04 0,01164473 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 1,114E-04 0,01113844 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 1,169E-04 0,01120556 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 1,346E-04 0,01238584 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 1,346E-04 0,01190946 ! phospholipid catabolic process GO:0009395 14 12 1,000 1,502E-04 0,01279223 ! positive regulation of ligase activity GO:0051351 99 69 2,000 1,608E-04 0,0132105 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 1,751E-04 0,0138854 ! negative regulation of organelle organization GO:0010639 115 72 2,000 1,825E-04 0,01399174 ! tube morphogenesis GO:0035239 118 73 2,000 1,901E-04 0,01410618 ! regulation of ligase activity GO:0051340 114 75 2,000 2,06E-04 0,01480573 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 2,067E-04 0,01440342 GO:0060675|ureteric bud morphogenesis, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 2,382E-04 0,01611516 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 2,494E-04 0,01638605 GO:0010498|proteasomal protein catabolic process, ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,72E-04 0,01737758 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,08E-04 0,01914405 ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,194E-04 0,01933114 GO:0060538|skeletal muscle organ development, ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,865E-04 0,02279295 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 3,865E-04 0,02222313 ! response to light stimulus GO:0009416 153 96 2,000 4,266E-04 0,023929 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 4,29E-04 0,02349414 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,29E-04 0,02294777 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 4,737E-04 0,02476328 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 4,737E-04 0,02421299 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 4,737E-04 0,02368662 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,206E-04 0,02547663 ! ureteric bud development GO:0001657 32 22 1,000 5,206E-04 0,02494587 ! neural tube closure GO:0001843 33 22 1,000 5,206E-04 0,02443677 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 5,696E-04 0,02620383 ! negative regulation of DNA replication GO:0008156 35 23 1,000 5,696E-04 0,02569003 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 5,696E-04 0,02519599 ! telomere organization GO:0032200 32 23 1,000 5,696E-04 0,02472059 GO:0000723|telomere maintenance, ! insulin receptor signaling pathway GO:0008286 40 24 1,000 6,208E-04 0,02644332 ! fat cell differentiation GO:0045444 37 24 1,000 6,208E-04 0,02596253 ! primary neural tube formation GO:0014020 35 24 1,000 6,208E-04 0,02549891 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 6,742E-04 0,02720404 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of chromosome organization GO:0033044 35 25 1,000 6,742E-04 0,02673501 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 7,297E-04 0,02844493 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 7,297E-04 0,02797085 ! negative regulation of protein polymerization GO:0032272 38 26 1,000 7,297E-04 0,02751231 ! inner ear morphogenesis GO:0042472 35 27 1,000 7,873E-04 0,02920622 ! myofibril assembly GO:0030239 36 27 1,000 7,873E-04 0,02874263 GO:0055002|striated muscle cell development, ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 8,471E-04 0,03044096 ! neural tube formation GO:0001841 41 28 1,000 8,471E-04 0,02997264 ! regulation of B cell activation GO:0050864 42 28 1,000 8,471E-04 0,02951851 ! muscle cell development GO:0055001 38 29 1,000 9,089E-04 0,03120213 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 9,729E-04 0,03290788 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 9,729E-04 0,03243096 ! regulation of microtubule-based process GO:0032886 58 30 1,000 9,729E-04 0,03196766 ! spindle organization GO:0007051 37 30 1,000 9,729E-04 0,03151741 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 1,039E-03 0,03319149 ! metanephros development GO:0001656 58 31 1,000 1,039E-03 0,03273681 ! cell fate specification GO:0001708 37 31 1,000 1,039E-03 0,03229442 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 1,107E-03 0,03395575 ! meiosis I GO:0007127 52 32 1,000 1,107E-03 0,03350896 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 1,107E-03 0,03307378 ! ear morphogenesis GO:0042471 42 33 1,000 1,178E-03 0,03472313 ! actomyosin structure organization GO:0031032 43 33 1,000 1,178E-03 0,0342836 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,25E-03 0,03593678 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 1,25E-03 0,03549311 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,324E-03 0,03714977 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! neural tube development GO:0021915 50 36 1,000 1,401E-03 0,03882417 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,56E-03 0,04272572 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 1,643E-03 0,04446308 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 1,643E-03 0,04394607 ! response to calcium ion GO:0051592 58 40 1,000 1,728E-03 0,04568383 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 1,728E-03 0,0451647 ! inner ear development GO:0048839 57 40 1,000 1,728E-03 0,04465723 ! epithelial cell differentiation GO:0030855 55 41 1,000 1,815E-03 0,04638157 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 1,904E-03 0,04811969 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 1,904E-03 0,04759665 ! embryonic skeletal system development GO:0048706 56 42 1,000 1,904E-03 0,04708486 ! response to insulin stimulus GO:0032868 63 43 1,000 1,995E-03 0,0488099 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 2,088E-03 0,05054784 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,183E-03 0,05229812 ! endocrine system development GO:0035270 83 47 1,000 2,379E-03 0,05640925 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 2,379E-03 0,05583365 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 2,379E-03 0,05526967 ! regulation of DNA replication GO:0006275 75 48 1,000 2,48E-03 0,05704172 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 2,583E-03 0,05882429 ! ear development GO:0043583 72 50 1,000 2,688E-03 0,06061692 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 2,688E-03 0,0600284 ! skeletal system morphogenesis GO:0048705 78 53 1,000 3,015E-03 0,06668616 ! kidney development GO:0001822 90 53 1,000 3,015E-03 0,06605105 ! single fertilization GO:0007338 59 53 1,000 3,015E-03 0,06542793 ! regulation of protein complex assembly GO:0043254 81 54 1,000 3,128E-03 0,06724547 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 3,479E-03 0,07409323 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 3,479E-03 0,07341348 ! negative regulation of kinase activity GO:0033673 100 58 1,000 3,6E-03 0,07527263 ! actin filament organization GO:0007015 95 59 1,000 3,723E-03 0,07713854 ! fertilization GO:0009566 68 60 1,000 3,847E-03 0,07901094 ! regulation of homeostatic process GO:0032844 105 60 1,000 3,847E-03 0,07831172 ! meiosis GO:0007126 96 61 1,000 3,974E-03 0,08017995 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 1,000 3,974E-03 0,07948273 ! negative regulation of cell growth GO:0030308 106 62 1,000 4,103E-03 0,08134684 ! meiotic cell cycle GO:0051321 97 62 1,000 4,103E-03 0,08065157 ! negative regulation of cell size GO:0045792 108 64 1,000 4,366E-03 0,08509245 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 4,366E-03 0,08437738 ! regulation of neuron differentiation GO:0045664 107 67 1,000 4,774E-03 0,09150677 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 4,914E-03 0,09341183 ! response to metal ion GO:0010038 103 70 1,000 5,2E-03 0,09803171 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,2E-03 0,0972347 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 5,346E-03 0,09915209 ! muscle cell differentiation GO:0042692 104 71 1,000 5,346E-03 0,09835887 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 5,493E-03 0,10027102 GO:0045937|positive regulation of phosphate metabolic process, ! cellular lipid catabolic process GO:0044242 105 73 1,000 5,642E-03 0,10218678 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 5,794E-03 0,10410599 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 5,794E-03 0,10329896 ! response to inorganic substance GO:0010035 115 75 1,000 5,947E-03 0,10521285 ! negative regulation of growth GO:0045926 123 75 1,000 5,947E-03 0,10440969 ! response to unfolded protein GO:0006986 99 76 1,000 6,102E-03 0,10631833 ! gland development GO:0048732 148 77 1,000 6,259E-03 0,10823008 ! positive regulation of protein modification process GO:0031401 107 78 1,000 6,417E-03 0,1101448 ! regulation of GTPase activity GO:0043087 129 80 1,000 6,74E-03 0,11482677 ! response to protein stimulus GO:0051789 111 81 1,000 6,904E-03 0,11675734 ! positive regulation of cell activation GO:0050867 120 81 1,000 6,904E-03 0,11590509 GO:0002696|positive regulation of leukocyte activation, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 7,407E-03 0,12345006 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 7,578E-03 0,12539632 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,699E-03 0,12648834 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 7,699E-03 0,12559126 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 7,699E-03 0,12470682 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 7,699E-03 0,12383474 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 7,699E-03 0,12297478 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,699E-03 0,12212668 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 7,699E-03 0,12129019 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,699E-03 0,12046509 ! sleep GO:0030431 11 5 0,000 7,699E-03 0,11965113 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,699E-03 0,11884811 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,699E-03 0,11805579 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,699E-03 0,11727396 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 7,699E-03 0,11650242 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 7,699E-03 0,11574097 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 7,699E-03 0,1149894 ! tongue development GO:0043586 6 5 0,000 7,699E-03 0,11424754 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 7,699E-03 0,11351518 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,699E-03 0,11279215 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 7,699E-03 0,11207828 ! cobalt ion transport GO:0006824 9 5 0,000 7,699E-03 0,11137338 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,699E-03 0,1106773 ! SMAD protein complex assembly GO:0007183 9 5 0,000 7,699E-03 0,10998986 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,699E-03 0,10931091 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,699E-03 0,10864029 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 7,699E-03 0,10797785 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,699E-03 0,10732344 ! embryonic camera-type eye development GO:0031076 8 5 0,000 7,699E-03 0,10667692 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 7,699E-03 0,10603813 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 7,699E-03 0,10540695 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,699E-03 0,10478324 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,699E-03 0,10416687 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,699E-03 0,10355771 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 7,699E-03 0,10295563 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 7,699E-03 0,10236051 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,699E-03 0,10177223 ! malate metabolic process GO:0006108 7 5 0,000 7,699E-03 0,10119067 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 7,699E-03 0,10061573 ! behavioral response to pain GO:0048266 7 5 0,000 7,699E-03 0,10004728 ! clathrin coat assembly GO:0048268 11 5 0,000 7,699E-03 0,09948521 ! phototransduction, visible light GO:0007603 6 5 0,000 7,699E-03 0,09892943 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,699E-03 0,09837982 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,699E-03 0,09783629 ! mating behavior GO:0007617 6 5 0,000 7,699E-03 0,09729873 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,699E-03 0,09676704 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,699E-03 0,09624113 ! rhythmic behavior GO:0007622 12 5 0,000 7,699E-03 0,09572091 ! copulation GO:0007620 7 5 0,000 7,699E-03 0,09520628 ! glial cell fate commitment GO:0021781 12 5 0,000 7,699E-03 0,09469715 ! protein maturation by protein folding GO:0022417 12 5 0,000 7,699E-03 0,09419345 ! embryonic hemopoiesis GO:0035162 10 5 0,000 7,699E-03 0,09369507 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,699E-03 0,09320194 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 7,699E-03 0,09271397 ! apoptotic cell clearance GO:0043277 13 5 0,000 7,699E-03 0,09223108 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,699E-03 0,0917532 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 7,699E-03 0,09128025 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,699E-03 0,09081214 ! response to protozoan GO:0001562 9 5 0,000 7,699E-03 0,09034882 ! positive regulation of glycolysis GO:0045821 11 5 0,000 7,699E-03 0,08989019 ! lymph vessel development GO:0001945 7 5 0,000 7,699E-03 0,0894362 ! endochondral ossification GO:0001958 12 5 0,000 7,699E-03 0,08898677 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,699E-03 0,08854184 ! parathyroid gland development GO:0060017 8 5 0,000 7,699E-03 0,08810133 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 7,699E-03 0,08766519 ! anagen GO:0042640 6 5 0,000 7,699E-03 0,08723334 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,699E-03 0,08680573 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,699E-03 0,08638228 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 7,699E-03 0,08596295 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 7,699E-03 0,08554767 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,699E-03 0,08513638 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 7,699E-03 0,08472903 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 7,699E-03 0,08432556 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,699E-03 0,08392591 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,699E-03 0,08353004 ! cardiac muscle fiber development GO:0048739 7 5 0,000 7,699E-03 0,08313788 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 7,699E-03 0,08274938 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 7,699E-03 0,0823645 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,699E-03 0,08198319 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,699E-03 0,08160538 ! ovulation GO:0030728 6 5 0,000 7,699E-03 0,08123105 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,699E-03 0,08086013 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 7,699E-03 0,08049258 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,699E-03 0,08012836 ! response to pH GO:0009268 9 5 0,000 7,699E-03 0,07976742 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,699E-03 0,07940972 ! proline biosynthetic process GO:0006561 6 5 0,000 7,699E-03 0,07905521 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,699E-03 0,07870386 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 7,699E-03 0,07835561 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,699E-03 0,07801043 ! polyol catabolic process GO:0046174 7 5 0,000 7,699E-03 0,07766828 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,699E-03 0,07732912 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,699E-03 0,0769929 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,699E-03 0,0766596 ! sister chromatid cohesion GO:0007062 9 5 0,000 7,699E-03 0,07632917 ! nerve growth factor processing GO:0032455 7 5 0,000 7,699E-03 0,07600158 ! urea metabolic process GO:0019627 6 5 0,000 7,699E-03 0,07567679 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 7,699E-03 0,07535476 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,699E-03 0,07503546 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 7,699E-03 0,07471885 ! neutrophil activation GO:0042119 5 5 0,000 7,699E-03 0,07440491 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,699E-03 0,07409359 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,699E-03 0,07378487 ! response to food GO:0032094 5 5 0,000 7,699E-03 0,07347871 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,699E-03 0,07317507 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,699E-03 0,07287394 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,699E-03 0,07257528 ! forebrain neuron development GO:0021884 7 5 0,000 7,699E-03 0,07227905 ! melanosome organization GO:0032438 7 5 0,000 7,699E-03 0,07198524 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,699E-03 0,0716938 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,699E-03 0,07140471 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 7,699E-03 0,07111794 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,699E-03 0,07083347 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 7,699E-03 0,07055127 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 7,699E-03 0,0702713 ! nucleoside transport GO:0015858 6 5 0,000 7,699E-03 0,06999355 ! nucleoside salvage GO:0043174 7 5 0,000 7,699E-03 0,06971798 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 7,699E-03 0,06944458 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,699E-03 0,06917331 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 7,699E-03 0,06890416 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,699E-03 0,06863709 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,699E-03 0,06837208 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,699E-03 0,06810911 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,699E-03 0,06784815 ! depyrimidination GO:0045008 8 5 0,000 7,699E-03 0,06758919 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 7,699E-03 0,0673322 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,699E-03 0,06707715 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 7,699E-03 0,06682403 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,699E-03 0,06657281 ! neuronal ion channel clustering GO:0045161 7 5 0,000 7,699E-03 0,06632348 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,699E-03 0,066076 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 7,699E-03 0,06583036 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 7,699E-03 0,06558655 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,699E-03 0,06534453 ! monocyte differentiation GO:0030224 8 5 0,000 7,699E-03 0,06510429 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 7,699E-03 0,06486582 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 7,699E-03 0,06462908 ! centrosome duplication GO:0051298 5 5 0,000 7,699E-03 0,06439407 ! response to UV-C GO:0010225 6 5 0,000 7,699E-03 0,06416075 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,699E-03 0,06392913 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 7,699E-03 0,06369917 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,699E-03 0,06347085 ! regulation of dendrite development GO:0050773 12 5 0,000 7,699E-03 0,06324417 ! peptidyl-arginine modification GO:0018195 7 5 0,000 7,699E-03 0,0630191 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,699E-03 0,06279563 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 7,699E-03 0,06257374 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 7,699E-03 0,06235341 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 7,699E-03 0,06213462 ! regulation of dopamine secretion GO:0014059 12 5 0,000 7,699E-03 0,06191737 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,699E-03 0,06170163 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 7,699E-03 0,06148739 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,699E-03 0,06127463 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,699E-03 0,06106334 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 7,699E-03 0,0608535 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,699E-03 0,0606451 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 7,699E-03 0,06043812 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 7,699E-03 0,06023254 ! neural tube patterning GO:0021532 6 5 0,000 7,699E-03 0,06002837 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,699E-03 0,05982557 ! histone demethylation GO:0016577 9 5 0,000 7,699E-03 0,05962413 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,699E-03 0,05942405 ! regulation of sterol transport GO:0032371 7 5 0,000 7,699E-03 0,05922531 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,699E-03 0,05902789 ! enteric nervous system development GO:0048484 8 5 0,000 7,699E-03 0,05883179 ! establishment of planar polarity GO:0001736 6 5 0,000 7,699E-03 0,05863698 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,699E-03 0,05844346 ! muscle cell proliferation GO:0033002 8 5 0,000 7,699E-03 0,05825121 ! transcription termination GO:0006353 8 5 0,000 7,699E-03 0,05806022 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 7,699E-03 0,05787048 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 7,699E-03 0,05768198 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 7,699E-03 0,0574947 ! regulation of respiratory burst GO:0060263 8 5 0,000 7,699E-03 0,05730863 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,699E-03 0,05712377 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,699E-03 0,05694009 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,699E-03 0,05675759 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 7,699E-03 0,05657626 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,699E-03 0,05639608 ! apical protein localization GO:0045176 6 5 0,000 7,699E-03 0,05621704 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,699E-03 0,05603914 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,699E-03 0,05586236 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,699E-03 0,05568669 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,699E-03 0,05551213 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 7,699E-03 0,05533865 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 7,699E-03 0,05516626 ! triglyceride catabolic process GO:0019433 6 5 0,000 7,699E-03 0,05499493 ! glial cell migration GO:0008347 10 5 0,000 7,699E-03 0,05482467 ! determination of adult lifespan GO:0008340 8 5 0,000 7,699E-03 0,05465546 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,699E-03 0,05448729 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,699E-03 0,05432015 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,699E-03 0,05415403 ! somatic stem cell maintenance GO:0035019 13 5 0,000 7,699E-03 0,05398893 ! cerebellar cortex formation GO:0021697 6 5 0,000 7,699E-03 0,05382483 ! neural plate development GO:0001840 6 5 0,000 7,699E-03 0,05366172 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 7,699E-03 0,0534996 ! regulation of sensory perception GO:0051931 6 5 0,000 7,699E-03 0,05333846 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 7,699E-03 0,05317828 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 7,699E-03 0,05301907 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 7,699E-03 0,0528608 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 7,699E-03 0,05270348 ! sensory cilium assembly GO:0035058 6 5 0,000 7,699E-03 0,05254709 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 7,699E-03 0,05239162 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,699E-03 0,05223707 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 7,699E-03 0,05208344 ! spindle assembly GO:0051225 5 5 0,000 7,699E-03 0,0519307 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 7,699E-03 0,05177885 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 7,699E-03 0,05162789 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,699E-03 0,05147781 ! organ regeneration GO:0031100 7 5 0,000 7,699E-03 0,0513286 ! NAD biosynthetic process GO:0009435 7 5 0,000 7,699E-03 0,05118025 ! carnitine metabolic process GO:0009437 5 5 0,000 7,699E-03 0,05103276 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 7,699E-03 0,05088611 ! cellular anion homeostasis GO:0030002 6 5 0,000 7,699E-03 0,05074031 GO:0055081|anion homeostasis, ! cell cycle arrest GO:0007050 150 86 1,000 7,751E-03 0,05093767 ! anatomical structure homeostasis GO:0060249 136 88 1,000 8,103E-03 0,05309596 ! regulation of neurogenesis GO:0050767 153 89 1,000 8,281E-03 0,05411096 ! cell fate commitment GO:0045165 141 92 1,000 8,827E-03 0,05751424 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 9,013E-03 0,05855676 ! tRNA transcription GO:0009304 11 6 0,000 9,232E-03 0,05981479 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,232E-03 0,05964678 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,232E-03 0,0594797 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,232E-03 0,05931355 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,232E-03 0,05914833 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,232E-03 0,05898403 ! regulation of helicase activity GO:0051095 11 6 0,000 9,232E-03 0,05882064 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,232E-03 0,05865815 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,232E-03 0,05849656 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,232E-03 0,05833586 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,232E-03 0,05817603 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,232E-03 0,05801708 ! prostate gland development GO:0030850 9 6 0,000 9,232E-03 0,057859 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,232E-03 0,05770177 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,232E-03 0,0575454 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,232E-03 0,05738987 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,232E-03 0,05723518 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,232E-03 0,05708132 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,232E-03 0,05692829 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,232E-03 0,05677607 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,232E-03 0,05662467 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,232E-03 0,05647407 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,232E-03 0,05632428 ! neuron adhesion GO:0007158 9 6 0,000 9,232E-03 0,05617527 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,232E-03 0,05602705 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,232E-03 0,05587961 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,232E-03 0,05573294 ! signal peptide processing GO:0006465 8 6 0,000 9,232E-03 0,05558705 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,232E-03 0,05544191 ! mRNA stabilization GO:0048255 15 6 0,000 9,232E-03 0,05529753 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,232E-03 0,0551539 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,232E-03 0,05501102 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,232E-03 0,05486887 ! opsonization GO:0008228 8 6 0,000 9,232E-03 0,05472745 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,232E-03 0,05458677 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,232E-03 0,0544468 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,232E-03 0,05430755 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,232E-03 0,05416901 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,232E-03 0,05403118 ! photoreceptor cell development GO:0042461 10 6 0,000 9,232E-03 0,05389404 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,232E-03 0,0537576 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,232E-03 0,05362185 ! mechanosensory behavior GO:0007638 8 6 0,000 9,232E-03 0,05348678 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,232E-03 0,05335239 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,232E-03 0,05321868 ! response to interferon-gamma GO:0034341 12 6 0,000 9,232E-03 0,05308563 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,232E-03 0,05295325 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,232E-03 0,05282152 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,232E-03 0,05269045 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,232E-03 0,05256003 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,232E-03 0,05243025 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,232E-03 0,05230111 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,232E-03 0,05217261 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,232E-03 0,05204474 ! thymic T cell selection GO:0045061 12 6 0,000 9,232E-03 0,05191749 ! protein lipoylation GO:0009249 10 6 0,000 9,232E-03 0,05179086 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,232E-03 0,05166485 ! pigment granule organization GO:0048753 11 6 0,000 9,232E-03 0,05153945 ! drug transport GO:0015893 6 6 0,000 9,232E-03 0,05141465 ! cysteine metabolic process GO:0006534 7 6 0,000 9,232E-03 0,05129046 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,232E-03 0,05116687 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,232E-03 0,05104387 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,232E-03 0,05092147 ! histidine metabolic process GO:0006547 6 6 0,000 9,232E-03 0,05079965 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,232E-03 0,05067841 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,232E-03 0,05055774 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,232E-03 0,05043765 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,232E-03 0,05031813 ! adenohypophysis development GO:0021984 10 6 0,000 9,232E-03 0,05019918 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,232E-03 0,05008078 ! hyperosmotic response GO:0006972 8 6 0,000 9,232E-03 0,04996295 ! microtubule nucleation GO:0007020 10 6 0,000 9,232E-03 0,04984566 ! ER overload response GO:0006983 7 6 0,000 9,232E-03 0,04972893 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,232E-03 0,04961274 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,232E-03 0,04949709 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,232E-03 0,04938198 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,232E-03 0,04926741 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,232E-03 0,04915336 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,232E-03 0,04903984 ! response to dietary excess GO:0002021 7 6 0,000 9,232E-03 0,04892685 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,232E-03 0,04881437 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,232E-03 0,04870241 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,232E-03 0,04859097 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,232E-03 0,04848003 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,232E-03 0,04836959 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,232E-03 0,04825966 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,232E-03 0,04815023 ! neuron apoptosis GO:0051402 8 6 0,000 9,232E-03 0,04804129 ! organic alcohol transport GO:0015850 9 6 0,000 9,232E-03 0,04793285 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,232E-03 0,04782489 ! T cell mediated immunity GO:0002456 12 6 0,000 9,232E-03 0,04771742 ! male sex determination GO:0030238 9 6 0,000 9,232E-03 0,04761043 ! carnitine transport GO:0015879 8 6 0,000 9,232E-03 0,04750392 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,232E-03 0,04739788 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,232E-03 0,04729232 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,232E-03 0,04718723 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 9,232E-03 0,0470826 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,232E-03 0,04697843 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,232E-03 0,04687473 ! parturition GO:0007567 12 6 0,000 9,232E-03 0,04677148 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,232E-03 0,04666869 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,232E-03 0,04656634 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,232E-03 0,04646445 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,232E-03 0,046363 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,232E-03 0,04626199 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,232E-03 0,04616142 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,232E-03 0,04606128 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,232E-03 0,04596158 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,232E-03 0,04586232 ! macrophage differentiation GO:0030225 10 6 0,000 9,232E-03 0,04576347 ! astrocyte development GO:0014002 14 6 0,000 9,232E-03 0,04566506 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,232E-03 0,04556706 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,232E-03 0,04546949 ! interaction with symbiont GO:0051702 8 6 0,000 9,232E-03 0,04537233 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,232E-03 0,04527559 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,232E-03 0,04517926 ! eating behavior GO:0042755 6 6 0,000 9,232E-03 0,04508334 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,232E-03 0,04498782 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,232E-03 0,04489271 ! response to copper ion GO:0046688 9 6 0,000 9,232E-03 0,044798 ! DNA topological change GO:0006265 8 6 0,000 9,232E-03 0,04470369 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,232E-03 0,04460977 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,232E-03 0,04451625 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,232E-03 0,04442312 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,232E-03 0,04433038 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,232E-03 0,04423802 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,232E-03 0,04414605 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,232E-03 0,04405446 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,232E-03 0,04396325 ! gas homeostasis GO:0033483 11 6 0,000 9,232E-03 0,04387242 ! hair follicle maturation GO:0048820 7 6 0,000 9,232E-03 0,04378196 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,232E-03 0,04369188 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,232E-03 0,04360216 ! Schwann cell development GO:0014044 14 6 0,000 9,232E-03 0,04351281 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,232E-03 0,04342383 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,232E-03 0,04333521 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,232E-03 0,04324695 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,232E-03 0,04315905 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,232E-03 0,0430715 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,232E-03 0,04298432 ! histone ubiquitination GO:0016574 7 6 0,000 9,232E-03 0,04289748 ! regulation of meiosis GO:0040020 10 6 0,000 9,232E-03 0,04281099 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,232E-03 0,04272485 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,232E-03 0,04263906 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,232E-03 0,04255361 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,232E-03 0,0424685 ! membrane to membrane docking GO:0022614 12 6 0,000 9,232E-03 0,04238374 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,232E-03 0,04229931 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,232E-03 0,04221521 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,232E-03 0,04213145 ! receptor internalization GO:0031623 9 6 0,000 9,232E-03 0,04204802 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,232E-03 0,04196492 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,232E-03 0,04188215 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,232E-03 0,04179971 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,232E-03 0,04171759 ! protein deubiquitination GO:0016579 8 6 0,000 9,232E-03 0,04163579 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,232E-03 0,04155431 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,232E-03 0,04147315 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,232E-03 0,0413923 ! axonal fasciculation GO:0007413 9 6 0,000 9,232E-03 0,04131177 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,232E-03 0,04123156 ! thiamin metabolic process GO:0006772 6 6 0,000 9,232E-03 0,04115165 ! midbrain development GO:0030901 6 6 0,000 9,232E-03 0,04107205 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,232E-03 0,04099276 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,232E-03 0,04091378 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,232E-03 0,0408351 ! progesterone metabolic process GO:0042448 8 6 0,000 9,232E-03 0,04075672 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,232E-03 0,04067864 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,232E-03 0,04060086 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,232E-03 0,04052338 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,232E-03 0,04044619 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,232E-03 0,0403693 ! adult feeding behavior GO:0008343 6 6 0,000 9,232E-03 0,0402927 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,232E-03 0,04021639 ! blastocyst growth GO:0001832 15 6 0,000 9,232E-03 0,04014036 ! pigment granule transport GO:0051904 12 6 0,000 9,232E-03 0,04006463 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,232E-03 0,03998918 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,232E-03 0,03991401 ! catecholamine transport GO:0051937 7 6 0,000 9,232E-03 0,03983912 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,232E-03 0,03976452 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,232E-03 0,03969019 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,232E-03 0,03961614 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,232E-03 0,03954237 ! protein prenylation GO:0018342 10 6 0,000 9,232E-03 0,03946887 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,232E-03 0,03939564 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,232E-03 0,03932269 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,232E-03 0,03925 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,232E-03 0,03917759 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 9,579E-03 0,04057613 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,01016191 0,04296397 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,01035949 0,04371894 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,010763 0,04533863 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,010763 0,04525574 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,010763 0,04517316 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,010763 0,04509087 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,010763 0,04500889 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,010763 0,04492721 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,010763 0,04484582 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,010763 0,04476472 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,010763 0,04468392 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,010763 0,04460341 ! reproductive behavior GO:0019098 12 7 0,000 0,010763 0,04452318 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,010763 0,04444325 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,010763 0,0443636 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,010763 0,04428424 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,010763 0,04420516 ! oligopeptide transport GO:0006857 11 7 0,000 0,010763 0,04412636 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,010763 0,04404785 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,010763 0,04396961 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,010763 0,04389165 ! RNA methylation GO:0001510 11 7 0,000 0,010763 0,04381397 ! pericardium development GO:0060039 8 7 0,000 0,010763 0,04373656 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,010763 0,04365942 ! fibril organization GO:0043206 13 7 0,000 0,010763 0,04358255 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,010763 0,04350596 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,010763 0,04342963 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,010763 0,04335357 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,010763 0,04327778 ! lipoprotein transport GO:0042953 9 7 0,000 0,010763 0,04320225 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,010763 0,04312699 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,010763 0,04305198 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,010763 0,04297724 ! estrogen metabolic process GO:0008210 14 7 0,000 0,010763 0,04290276 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,010763 0,04282853 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,010763 0,04275456 ! chemosensory behavior GO:0007635 9 7 0,000 0,010763 0,04268085 ! microtubule bundle formation GO:0001578 8 7 0,000 0,010763 0,04260738 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,010763 0,04253418 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,010763 0,04246122 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,010763 0,04238851 ! leukocyte degranulation GO:0043299 10 7 0,000 0,010763 0,04231605 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,010763 0,04224384 ! reflex GO:0060004 12 7 0,000 0,010763 0,04217187 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,010763 0,04210015 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,010763 0,04202868 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,010763 0,04195744 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,010763 0,04188645 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,010763 0,04181569 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,010763 0,04174518 ! spinal cord patterning GO:0021511 7 7 0,000 0,010763 0,0416749 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,010763 0,04160486 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,010763 0,04153505 ! adrenal gland development GO:0030325 17 7 0,000 0,010763 0,04146548 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,010763 0,04139614 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,010763 0,04132703 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,010763 0,04125815 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,010763 0,0411895 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,010763 0,04112108 ! endosome organization GO:0007032 10 7 0,000 0,010763 0,04105289 ! thyroid hormone generation GO:0006590 11 7 0,000 0,010763 0,04098492 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,010763 0,04091717 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,010763 0,04084965 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,010763 0,04078236 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,010763 0,04071528 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,010763 0,04064842 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,010763 0,04058179 ! galactose metabolic process GO:0006012 10 7 0,000 0,010763 0,04051537 ! vesicle fusion GO:0006906 15 7 0,000 0,010763 0,04044917 ! intracellular pH reduction GO:0051452 10 7 0,000 0,010763 0,04038318 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,010763 0,04031741 ! organ growth GO:0035265 11 7 0,000 0,010763 0,04025185 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,010763 0,04018651 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,010763 0,04012138 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,010763 0,04005646 ! retinol metabolic process GO:0042572 9 7 0,000 0,010763 0,03999175 ! behavioral fear response GO:0001662 13 7 0,000 0,010763 0,03992724 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,010763 0,03986295 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,010763 0,03979886 ! rRNA modification GO:0000154 12 7 0,000 0,010763 0,03973498 ! protein heterooligomerization GO:0051291 10 7 0,000 0,010763 0,0396713 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,010763 0,03960782 ! response to UV-B GO:0010224 11 7 0,000 0,010763 0,03954455 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,010763 0,03948148 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,010763 0,03941862 ! intermediate filament organization GO:0045109 11 7 0,000 0,010763 0,03935595 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,010763 0,03929348 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,010763 0,0392312 ! fibrinolysis GO:0042730 9 7 0,000 0,010763 0,03916913 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,010763 0,03910725 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,010763 0,03904557 ! B cell lineage commitment GO:0002326 17 7 0,000 0,010763 0,03898408 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,010763 0,03892278 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,010763 0,03886168 ! response to tropane GO:0014073 13 7 0,000 0,010763 0,03880077 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,010763 0,03874005 ! melanosome localization GO:0032400 10 7 0,000 0,010763 0,03867952 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,010763 0,03861917 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,010763 0,03855902 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,010763 0,03849905 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,010763 0,03843927 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,010763 0,03837967 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,010763 0,03832026 ! mast cell activation GO:0045576 9 7 0,000 0,010763 0,03826104 ! multicellular organismal aging GO:0010259 11 7 0,000 0,010763 0,03820199 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,010763 0,03814313 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,010763 0,03808445 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,010763 0,03802595 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,010763 0,03796762 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,010763 0,03790948 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,010763 0,03785151 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,010763 0,03779373 ! T cell lineage commitment GO:0002360 12 7 0,000 0,010763 0,03773611 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,010763 0,03767868 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,010763 0,03762141 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,010763 0,03756433 ! regulation of lipid transport GO:0032368 13 7 0,000 0,010763 0,03750741 ! response to tumor cell GO:0002347 12 7 0,000 0,010763 0,03745067 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,010763 0,03739409 ! neuroblast proliferation GO:0007405 13 7 0,000 0,010763 0,03733769 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,010763 0,03728146 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,010763 0,0372254 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,010763 0,0371695 ! diuresis GO:0030146 12 7 0,000 0,010763 0,03711378 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,010763 0,03705822 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,010763 0,03700283 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,010763 0,0369476 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,010763 0,03689253 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,010763 0,03683763 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,010763 0,0367829 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,010763 0,03672832 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,010763 0,03667391 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,010763 0,03661966 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,010763 0,03656557 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,010763 0,03651164 ! lymph node development GO:0048535 9 7 0,000 0,010763 0,03645786 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,010763 0,03640425 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,010763 0,03635079 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,010763 0,03629749 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,010763 0,03624435 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,010763 0,03619136 ! ATP catabolic process GO:0006200 10 7 0,000 0,010763 0,03613853 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,010763 0,03608585 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,010763 0,03603332 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,010763 0,03598095 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,010763 0,03592872 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,010763 0,03587665 ! muscle adaptation GO:0043500 12 7 0,000 0,010763 0,03582473 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,010763 0,03577296 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,010763 0,03572134 ! retina homeostasis GO:0001895 9 7 0,000 0,010763 0,03566987 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,010763 0,03561855 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,010763 0,03556737 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,010763 0,03551634 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,010763 0,03546546 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,010763 0,03541472 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,010763 0,03536413 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,010763 0,03531368 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01229143 0,04027107 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01229143 0,04021378 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01229143 0,04015666 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01229143 0,0400997 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01229143 0,0400429 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01229143 0,03998627 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01229143 0,03992979 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01229143 0,03987347 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01229143 0,03981731 ! phosphate transport GO:0006817 10 8 0,000 0,01229143 0,03976131 ! N-glycan processing GO:0006491 12 8 0,000 0,01229143 0,03970546 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01229143 0,03964978 ! UTP metabolic process GO:0046051 8 8 0,000 0,01229143 0,03959424 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01229143 0,03953887 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01229143 0,03948365 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01229143 0,03942858 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01229143 0,03937366 ! succinate metabolic process GO:0006105 14 8 0,000 0,01229143 0,0393189 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01229143 0,03926429 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01229143 0,03920983 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01229143 0,03915553 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01229143 0,03910137 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01229143 0,03904736 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01229143 0,0389935 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01229143 0,03893979 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01229143 0,03888623 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01229143 0,03883282 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01229143 0,03877955 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01229143 0,03872643 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01229143 0,03867345 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01229143 0,03862062 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01229143 0,03856793 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01229143 0,03851538 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01229143 0,03846298 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01229143 0,03841072 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01229143 0,0383586 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01229143 0,03830663 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01229143 0,03825479 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01229143 0,0382031 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01229143 0,03815154 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01229143 0,03810012 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01229143 0,03804884 ! melanin metabolic process GO:0006582 12 8 0,000 0,01229143 0,0379977 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01229143 0,0379467 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01229143 0,03789583 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01229143 0,0378451 ! macrophage activation GO:0042116 12 8 0,000 0,01229143 0,03779451 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01229143 0,03774405 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01229143 0,03769372 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01229143 0,03764353 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01229143 0,03759347 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01229143 0,03754355 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01229143 0,03749375 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01229143 0,03744409 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01229143 0,03739456 ! ruffle organization GO:0031529 11 8 0,000 0,01229143 0,03734517 ! osteoblast development GO:0002076 13 8 0,000 0,01229143 0,0372959 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01229143 0,03724676 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01229143 0,03719775 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01229143 0,03714887 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01229143 0,03710012 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01229143 0,03705149 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01229143 0,037003 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01229143 0,03695463 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01229143 0,03690638 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01229143 0,03685827 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01229143 0,03681027 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01229143 0,03676241 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01229143 0,03671466 ! segment specification GO:0007379 10 8 0,000 0,01229143 0,03666704 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01229143 0,03661955 ! cellular extravasation GO:0045123 11 8 0,000 0,01229143 0,03657217 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01229143 0,03652492 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01229143 0,03647779 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01229143 0,03643079 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01229143 0,0363839 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01229143 0,03633713 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01229143 0,03629049 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01229143 0,03624396 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01229143 0,03619755 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01229143 0,03615127 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01229143 0,0361051 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01229143 0,03605904 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01229143 0,03601311 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01229143 0,03596729 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01229143 0,03592159 ! icosanoid secretion GO:0032309 12 8 0,000 0,01229143 0,035876 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01229143 0,03583053 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01229143 0,03578518 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01229143 0,03573994 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01229143 0,03569481 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01229143 0,0356498 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01229143 0,0356049 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01229143 0,03556011 ! sterol catabolic process GO:0016127 9 8 0,000 0,01229143 0,03551544 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01229143 0,03547088 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01229143 0,03542643 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01229143 0,03538209 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01229143 0,03533786 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01229143 0,03529375 ! prophase GO:0051324 11 8 0,000 0,01229143 0,03524974 ! S phase GO:0051320 8 8 0,000 0,01229143 0,03520584 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01229143 0,03516205 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01229143 0,03511837 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01229143 0,0350748 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01229143 0,03503134 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01229143 0,03498798 ! hormone catabolic process GO:0042447 13 8 0,000 0,01229143 0,03494473 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01229143 0,03490159 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01229143 0,03485856 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01229143 0,03481563 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01229143 0,0347728 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01229143 0,03473009 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01229143 0,03468747 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01229143 0,03464496 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01229143 0,03460256 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01229143 0,03456026 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01229143 0,03451806 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01229143 0,03447596 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01229143 0,03443397 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01229143 0,03439208 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01229143 0,03435029 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01229143 0,0343086 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01381759 0,03852177 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01381759 0,03847513 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01381759 0,03842861 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01381759 0,0383822 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01381759 0,0383359 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01381759 0,03828971 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01381759 0,03824363 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01381759 0,03819767 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01381759 0,03815181 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01381759 0,03810607 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01381759 0,03806043 ! GTP metabolic process GO:0046039 9 9 0,000 0,01381759 0,0380149 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01381759 0,03796949 ! social behavior GO:0035176 14 9 0,000 0,01381759 0,03792418 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01381759 0,03787897 ! artery development GO:0060840 19 9 0,000 0,01381759 0,03783388 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01381759 0,03778889 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01381759 0,03774401 ! response to pain GO:0048265 16 9 0,000 0,01381759 0,03769924 ! protein complex disassembly GO:0043241 17 9 0,000 0,01381759 0,03765457 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01381759 0,03761001 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01381759 0,03756556 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01381759 0,0375212 ! lung alveolus development GO:0048286 17 9 0,000 0,01381759 0,03747696 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01381759 0,03743281 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01381759 0,03738878 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01381759 0,03734484 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01381759 0,03730101 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01381759 0,03725728 ! protein targeting to ER GO:0045047 19 9 0,000 0,01381759 0,03721365 ! T cell selection GO:0045058 18 9 0,000 0,01381759 0,03717013 ! endoderm development GO:0007492 12 9 0,000 0,01381759 0,03712671 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01381759 0,03708338 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01381759 0,03704016 ! arginine catabolic process GO:0006527 10 9 0,000 0,01381759 0,03699704 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01381759 0,03695402 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01381759 0,0369111 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01381759 0,03686828 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01381759 0,03682556 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01381759 0,03678294 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01381759 0,03674042 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01381759 0,03669799 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01381759 0,03665566 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01381759 0,03661343 ! mannose metabolic process GO:0006013 9 9 0,000 0,01381759 0,0365713 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01381759 0,03652926 ! receptor clustering GO:0043113 15 9 0,000 0,01381759 0,03648732 ! epithelial cell development GO:0002064 10 9 0,000 0,01381759 0,03644548 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01381759 0,03640373 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01381759 0,03636208 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01381759 0,03632053 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01381759 0,03627906 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01381759 0,0362377 ! motor axon guidance GO:0008045 14 9 0,000 0,01381759 0,03619642 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01381759 0,03615524 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01381759 0,03611416 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01381759 0,03607317 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01381759 0,03603227 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01381759 0,03599146 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01381759 0,03595075 ! DNA ligation GO:0006266 14 9 0,000 0,01381759 0,03591012 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01381759 0,03586959 ! response to amine stimulus GO:0014075 13 9 0,000 0,01381759 0,03582915 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01381759 0,03578881 ! erythrocyte development GO:0048821 11 9 0,000 0,01381759 0,03574855 ! renal water homeostasis GO:0003091 14 9 0,000 0,01381759 0,03570838 ! postreplication repair GO:0006301 11 9 0,000 0,01381759 0,03566831 ! mRNA cleavage GO:0006379 13 9 0,000 0,01381759 0,03562832 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01381759 0,03558842 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01381759 0,03554861 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01381759 0,03550889 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01381759 0,03546926 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01381759 0,03542972 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01381759 0,03539027 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01381759 0,0353509 ! acid secretion GO:0046717 14 9 0,000 0,01381759 0,03531162 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01381759 0,03527243 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01381759 0,03523333 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01381759 0,03519431 ! purine base metabolic process GO:0006144 18 9 0,000 0,01381759 0,03515538 ! oocyte differentiation GO:0009994 12 9 0,000 0,01381759 0,03511653 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01381759 0,03507777 ! spleen development GO:0048536 15 9 0,000 0,01381759 0,0350391 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01381759 0,03500051 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01381759 0,034962 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01381759 0,03492358 ! detection of calcium ion GO:0005513 13 9 0,000 0,01381759 0,03488525 ! blastocyst formation GO:0001825 12 9 0,000 0,01381759 0,034847 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01381759 0,03480883 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01381759 0,03477074 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01381759 0,03473274 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01381759 0,03469483 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01381759 0,03465699 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01381759 0,03461924 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01381759 0,03458157 ! prepulse inhibition GO:0060134 14 9 0,000 0,01381759 0,03454398 ! embryonic placenta development GO:0001892 12 9 0,000 0,01381759 0,03450647 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01381759 0,03446905 ! insulin secretion GO:0030073 17 9 0,000 0,01381759 0,0344317 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01381759 0,03439444 ! response to nicotine GO:0035094 16 9 0,000 0,01381759 0,03435725 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01381759 0,03432015 ! nucleus localization GO:0051647 15 9 0,000 0,01381759 0,03428313 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01381759 0,03424619 ! localization within membrane GO:0051668 15 9 0,000 0,01381759 0,03420932 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01534148 0,0379413 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01534148 0,03790054 ! neuron fate specification GO:0048665 11 10 0,000 0,01534148 0,03785988 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01534148 0,0378193 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01534148 0,03777881 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01534148 0,0377384 ! synapsis GO:0007129 13 10 0,000 0,01534148 0,03769808 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01534148 0,03765785 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01534148 0,0376177 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01534148 0,03757764 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01534148 0,03753767 ! sulfate transport GO:0008272 12 10 0,000 0,01534148 0,03749778 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01534148 0,03745797 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01534148 0,03741825 ! androgen metabolic process GO:0008209 13 10 0,000 0,01534148 0,03737861 ! phospholipid efflux GO:0033700 16 10 0,000 0,01534148 0,03733905 ! hippocampus development GO:0021766 19 10 0,000 0,01534148 0,03729958 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01534148 0,0372602 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01534148 0,03722089 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01534148 0,03718167 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01534148 0,03714253 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01534148 0,03710348 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01534148 0,0370645 ! pathogenesis GO:0009405 13 10 0,000 0,01534148 0,03702561 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01534148 0,0369868 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01534148 0,03694807 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01534148 0,03690942 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01534148 0,03687085 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01534148 0,03683237 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01534148 0,03679396 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01534148 0,03675563 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01534148 0,03671738 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01534148 0,03667922 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01534148 0,03664113 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01534148 0,03660312 ! response to X-ray GO:0010165 16 10 0,000 0,01534148 0,03656519 ! B cell proliferation GO:0042100 14 10 0,000 0,01534148 0,03652734 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01534148 0,03648956 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01534148 0,03645187 ! forebrain cell migration GO:0021885 17 10 0,000 0,01534148 0,03641425 ! lipid digestion GO:0044241 15 10 0,000 0,01534148 0,03637671 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01534148 0,03633924 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01534148 0,03630186 ! UV protection GO:0009650 14 10 0,000 0,01534148 0,03626455 ! entry into host cell GO:0030260 20 10 0,000 0,01534148 0,03622732 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01534148 0,03619016 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01534148 0,03615308 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01534148 0,03611608 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01534148 0,03607915 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01534148 0,03604229 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01534148 0,03600552 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01534148 0,03596881 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01534148 0,03593219 ! regulation of organ growth GO:0046620 11 10 0,000 0,01534148 0,03589563 ! response to dsRNA GO:0043331 18 10 0,000 0,01534148 0,03585915 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01534148 0,03582275 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01534148 0,03578642 ! embryonic axis specification GO:0000578 12 10 0,000 0,01534148 0,03575016 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01534148 0,03571397 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01534148 0,03567786 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01534148 0,03564182 ! cranial nerve development GO:0021545 12 10 0,000 0,01534148 0,03560586 ! fucose catabolic process GO:0019317 16 10 0,000 0,01534148 0,03556997 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01534148 0,03553415 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01534148 0,0354984 ! protein sumoylation GO:0016925 12 10 0,000 0,01534148 0,03546272 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01534148 0,03542711 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01534148 0,03539158 ! zymogen activation GO:0031638 14 10 0,000 0,01534148 0,03535612 ! salivary gland development GO:0007431 22 10 0,000 0,01534148 0,03532073 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01534148 0,03528541 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01534148 0,03525016 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01534148 0,03521498 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01534148 0,03517987 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01534148 0,03514483 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01534148 0,03510986 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01534148 0,03507496 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01534148 0,03504013 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01534148 0,03500536 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01534148 0,03497067 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01534148 0,03493605 ! detection of bacterium GO:0016045 10 10 0,000 0,01534148 0,03490149 ! embryonic gut development GO:0048566 11 10 0,000 0,01534148 0,034867 ! activation of innate immune response GO:0002218 10 10 0,000 0,01534148 0,03483258 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01534148 0,03479823 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01534148 0,03476395 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01534148 0,03472973 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01534148 0,03469558 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01534148 0,0346615 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01534148 0,03462748 ! rRNA transcription GO:0009303 17 11 0,000 0,0168631 0,03802464 ! respiratory burst GO:0045730 14 11 0,000 0,0168631 0,0379874 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0168631 0,03795023 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0168631 0,03791313 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0168631 0,03787611 ! virus-host interaction GO:0019048 17 11 0,000 0,0168631 0,03783916 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,0168631 0,03780228 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,0168631 0,03776547 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,0168631 0,03772873 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0168631 0,03769207 ! RNA polyadenylation GO:0043631 19 11 0,000 0,0168631 0,03765547 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0168631 0,03761895 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,0168631 0,0375825 ! mating GO:0007618 14 11 0,000 0,0168631 0,03754612 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,0168631 0,0375098 ! T cell proliferation GO:0042098 20 11 0,000 0,0168631 0,03747356 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0168631 0,03743739 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0168631 0,03740129 ! bone resorption GO:0045453 16 11 0,000 0,0168631 0,03736526 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0168631 0,03732929 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0168631 0,0372934 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0168631 0,03725758 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,0168631 0,03722182 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0168631 0,03718613 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0168631 0,03715051 ! syncytium formation GO:0006949 15 11 0,000 0,0168631 0,03711496 ! plasma membrane organization GO:0007009 18 11 0,000 0,0168631 0,03707948 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0168631 0,03704407 ! focal adhesion formation GO:0048041 24 11 0,000 0,0168631 0,03700872 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0168631 0,03697344 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0168631 0,03693823 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,0168631 0,03690308 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0168631 0,036868 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0168631 0,03683299 ! adult heart development GO:0007512 11 11 0,000 0,0168631 0,03679804 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0168631 0,03676316 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,0168631 0,03672835 ! temperature homeostasis GO:0001659 16 11 0,000 0,0168631 0,0366936 ! L-glutamate transport GO:0015813 16 11 0,000 0,0168631 0,03665892 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0168631 0,0366243 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0168631 0,03658975 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0168631 0,03655527 ! stem cell development GO:0048864 29 11 0,000 0,0168631 0,03652084 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0168631 0,03648649 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0168631 0,0364522 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0168631 0,03641797 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0168631 0,03638381 ! vasoconstriction GO:0042310 15 11 0,000 0,0168631 0,03634971 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0168631 0,03631567 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0168631 0,0362817 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0168631 0,03624779 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0168631 0,03621395 ! ribosome assembly GO:0042255 13 11 0,000 0,0168631 0,03618017 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,0168631 0,03614645 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,0168631 0,03611279 ! chromatin silencing GO:0006342 19 11 0,000 0,0168631 0,0360792 ! nucleosome positioning GO:0016584 13 11 0,000 0,0168631 0,03604567 ! T cell homeostasis GO:0043029 20 11 0,000 0,0168631 0,0360122 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0168631 0,03597879 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0168631 0,03594545 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0168631 0,03591216 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0168631 0,03587894 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0168631 0,03584578 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0168631 0,03581268 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0168631 0,03577965 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,0168631 0,03574667 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,0168631 0,03571375 ! male genitalia development GO:0030539 13 11 0,000 0,0168631 0,0356809 ! cholesterol efflux GO:0033344 19 11 0,000 0,0168631 0,0356481 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0168631 0,03561537 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0168631 0,03558269 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0168631 0,03555008 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0168631 0,03551752 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0168631 0,03548503 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0168631 0,03545259 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,0168631 0,03542022 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,0168631 0,0353879 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,0168631 0,03535564 ! lysogeny GO:0030069 18 11 0,000 0,0168631 0,03532344 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0168631 0,0352913 ! acrosome reaction GO:0007340 13 11 0,000 0,0168631 0,03525922 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,0168631 0,03522719 ! lactation GO:0007595 20 12 0,000 0,01838246 0,0383663 ! reproductive cellular process GO:0048610 14 12 0,000 0,01838246 0,03833151 ! tRNA modification GO:0006400 14 12 0,000 0,01838246 0,03829679 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01838246 0,03826214 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01838246 0,03822754 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01838246 0,03819301 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01838246 0,03815854 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01838246 0,03812413 ! non-recombinational repair GO:0000726 19 12 0,000 0,01838246 0,03808978 GO:0006303|double-strand break repair via nonhomologous end joining, ! peroxisomal transport GO:0043574 21 12 0,000 0,01838246 0,0380555 ! cartilage condensation GO:0001502 18 12 0,000 0,01838246 0,03802128 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01838246 0,03798712 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01838246 0,03795302 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01838246 0,03791898 ! heart looping GO:0001947 15 12 0,000 0,01838246 0,037885 ! palate development GO:0060021 15 12 0,000 0,01838246 0,03785108 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01838246 0,03781723 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01838246 0,03778343 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01838246 0,0377497 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01838246 0,03771602 ! arginine metabolic process GO:0006525 13 12 0,000 0,01838246 0,03768241 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01838246 0,03764885 ! methionine metabolic process GO:0006555 13 12 0,000 0,01838246 0,03761536 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01838246 0,03758192 ! Golgi organization GO:0007030 18 12 0,000 0,01838246 0,03754854 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01838246 0,03751523 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01838246 0,03748197 ! monoamine transport GO:0015844 13 12 0,000 0,01838246 0,03744877 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01838246 0,03741563 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01838246 0,03738255 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01838246 0,03734952 ! L-amino acid transport GO:0015807 20 12 0,000 0,01838246 0,03731656 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01838246 0,03728365 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01838246 0,0372508 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01838246 0,03721801 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01838246 0,03718528 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01838246 0,0371526 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01838246 0,03711998 ! cerebellum development GO:0021549 13 12 0,000 0,01838246 0,03708742 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01838246 0,03705492 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01838246 0,03702247 ! histone acetylation GO:0016573 23 12 0,000 0,01838246 0,03699008 ! histone methylation GO:0016571 15 12 0,000 0,01838246 0,03695774 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01838246 0,03692547 ! gland morphogenesis GO:0022612 23 12 0,000 0,01838246 0,03689325 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01838246 0,03686108 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01838246 0,03682897 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01838246 0,03679692 ! response to gamma radiation GO:0010332 20 12 0,000 0,01838246 0,03676492 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01838246 0,03673298 ! intestinal absorption GO:0050892 19 12 0,000 0,01838246 0,03670109 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01838246 0,03666926 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01838246 0,03663749 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01838246 0,03660577 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01838246 0,0365741 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01838246 0,03654249 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01838246 0,03651093 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01838246 0,03647943 ! microspike assembly GO:0030035 23 12 0,000 0,01838246 0,03644798 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01838246 0,03641659 ! response to cold GO:0009409 14 12 0,000 0,01838246 0,03638525 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01989956 0,03935424 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01989956 0,03932043 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01989956 0,03928668 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01989956 0,03925299 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01989956 0,03921935 ! water transport GO:0006833 17 13 0,000 0,01989956 0,03918577 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01989956 0,03915225 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01989956 0,03911879 ! lipid localization GO:0010876 24 13 0,000 0,01989956 0,03908538 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01989956 0,03905203 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01989956 0,03901874 ! organelle fusion GO:0048284 28 13 0,000 0,01989956 0,0389855 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01989956 0,03895232 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01989956 0,0389192 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01989956 0,03888614 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01989956 0,03885312 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01989956 0,03882017 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01989956 0,03878727 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01989956 0,03875443 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01989956 0,03872164 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01989956 0,03868891 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01989956 0,03865623 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01989956 0,03862361 ! NAD metabolic process GO:0019674 21 13 0,000 0,01989956 0,03859105 ! exocrine system development GO:0035272 27 13 0,000 0,01989956 0,03855853 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01989956 0,03852608 ! bone mineralization GO:0030282 15 13 0,000 0,01989956 0,03849368 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01989956 0,03846133 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01989956 0,03842904 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01989956 0,0383968 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01989956 0,03836461 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01989956 0,03833248 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01989956 0,0383004 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01989956 0,03826838 ! genitalia development GO:0048806 15 13 0,000 0,01989956 0,03823641 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01989956 0,03820449 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01989956 0,03817263 ! cellular pigmentation GO:0033059 24 13 0,000 0,01989956 0,03814082 ! tissue regeneration GO:0042246 21 13 0,000 0,01989956 0,03810906 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01989956 0,03807736 ! cofactor transport GO:0051181 19 13 0,000 0,01989956 0,0380457 ! NADP metabolic process GO:0006739 18 13 0,000 0,01989956 0,0380141 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01989956 0,03798256 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01989956 0,03795106 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01989956 0,03791962 ! gas transport GO:0015669 18 13 0,000 0,01989956 0,03788823 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01989956 0,03785689 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01989956 0,0378256 ! regulation of axon extension GO:0030516 23 13 0,000 0,01989956 0,03779437 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01989956 0,03776319 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01989956 0,03773205 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01989956 0,03770097 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01989956 0,03766994 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01989956 0,03763896 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01989956 0,03760804 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0214144 0,04043769 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0214144 0,04040452 ! superoxide anion generation GO:0042554 18 14 0,000 0,0214144 0,0403714 ! neuron maturation GO:0042551 21 14 0,000 0,0214144 0,04033834 ! regulation of S phase GO:0033261 18 14 0,000 0,0214144 0,04030533 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0214144 0,04027237 ! myotube differentiation GO:0014902 21 14 0,000 0,0214144 0,04023947 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,0214144 0,04020662 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0214144 0,04017382 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0214144 0,04014108 ! inositol metabolic process GO:0006020 20 14 0,000 0,0214144 0,0401084 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0214144 0,04007576 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0214144 0,04004318 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0214144 0,04001065 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0214144 0,03997817 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0214144 0,03994575 ! response to cAMP GO:0051591 19 14 0,000 0,0214144 0,03991338 ! limbic system development GO:0021761 25 14 0,000 0,0214144 0,03988106 ! startle response GO:0001964 21 14 0,000 0,0214144 0,03984879 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0214144 0,03981658 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0214144 0,03978442 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0214144 0,03975231 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0214144 0,03972025 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0214144 0,03968824 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0214144 0,03965629 ! glycine metabolic process GO:0006544 22 14 0,000 0,0214144 0,03962438 ! pituitary gland development GO:0021983 23 14 0,000 0,0214144 0,03959253 ! cellular response to starvation GO:0009267 21 14 0,000 0,0214144 0,03956073 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0214144 0,03952898 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0214144 0,03949728 ! regulation of heart rate GO:0002027 23 14 0,000 0,0214144 0,03946563 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0214144 0,03943403 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0214144 0,03940249 ! embryo implantation GO:0007566 27 14 0,000 0,0214144 0,03937099 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0214144 0,03933954 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0214144 0,03930815 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0214144 0,0392768 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0214144 0,03924551 ! axon cargo transport GO:0008088 27 14 0,000 0,0214144 0,03921426 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0214144 0,03918306 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0214144 0,03915192 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0214144 0,03912082 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0214144 0,03908977 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0214144 0,03905877 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0214144 0,03902782 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0214144 0,03899692 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0214144 0,03896607 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0214144 0,03893526 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0214144 0,03890451 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0214144 0,0388738 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0214144 0,03884315 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0214144 0,03881254 ! muscle maintenance GO:0046716 19 14 0,000 0,0214144 0,03878198 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0214144 0,03875146 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0214144 0,038721 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0214144 0,03869058 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0214144 0,03866021 ! cell killing GO:0001906 20 14 0,000 0,0214144 0,03862989 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,0214144 0,03859962 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0214144 0,03856939 ! cilium assembly GO:0042384 20 14 0,000 0,0214144 0,03853921 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0214144 0,03850908 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02292698 0,04119692 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02292698 0,04116476 ! metencephalon development GO:0022037 19 15 0,000 0,02292698 0,04113265 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02292698 0,04110059 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02292698 0,04106858 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02292698 0,04103662 ! skin development GO:0043588 25 15 0,000 0,02292698 0,04100471 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02292698 0,04097285 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02292698 0,04094103 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02292698 0,04090927 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02292698 0,04087756 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02292698 0,0408459 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02292698 0,04081428 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02292698 0,04078272 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02292698 0,0407512 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02292698 0,04071973 ! adult walking behavior GO:0007628 25 15 0,000 0,02292698 0,04068831 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02292698 0,04065694 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02292698 0,04062562 ! myoblast differentiation GO:0045445 27 15 0,000 0,02292698 0,04059434 ! centrosome cycle GO:0007098 16 15 0,000 0,02292698 0,04056312 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02292698 0,04053194 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02292698 0,04050081 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02292698 0,04046973 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02292698 0,04043869 ! cerebral cortex development GO:0021987 29 15 0,000 0,02292698 0,0404077 ! response to osmotic stress GO:0006970 22 15 0,000 0,02292698 0,04037676 ! vesicle coating GO:0006901 25 15 0,000 0,02292698 0,04034587 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02292698 0,04031502 ! DNA integration GO:0015074 22 15 0,000 0,02292698 0,04028423 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02292698 0,04025347 ! peptide secretion GO:0002790 27 15 0,000 0,02292698 0,04022277 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02292698 0,04019211 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02292698 0,0401615 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02292698 0,04013094 ! neuron recognition GO:0008038 22 15 0,000 0,02292698 0,04010042 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02292698 0,04006995 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02292698 0,04003952 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02292698 0,04000914 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02292698 0,03997881 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02292698 0,03994852 ! biomineral formation GO:0031214 18 15 0,000 0,02292698 0,03991828 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02292698 0,03988809 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02292698 0,03985794 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02292698 0,03982783 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02292698 0,03979777 ! organic cation transport GO:0015695 19 15 0,000 0,02292698 0,03976776 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02292698 0,03973779 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02292698 0,03970787 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02292698 0,03967799 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02292698 0,03964816 ! defense response to virus GO:0051607 27 15 0,000 0,02292698 0,03961837 ! peptide hormone processing GO:0016486 19 15 0,000 0,02292698 0,03958863 ! protein secretion GO:0009306 27 16 0,000 0,02443731 0,0421649 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02443731 0,0421333 ! hormone secretion GO:0046879 25 16 0,000 0,02443731 0,04210173 ! bone remodeling GO:0046849 24 16 0,000 0,02443731 0,04207022 ! endothelial cell migration GO:0043542 22 16 0,000 0,02443731 0,04203876 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02443731 0,04200734 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02443731 0,04197596 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02443731 0,04194464 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02443731 0,04191336 ! glial cell development GO:0021782 24 16 0,000 0,02443731 0,04188213 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02443731 0,04185094 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02443731 0,0418198 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02443731 0,04178871 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02443731 0,04175766 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02443731 0,04172666 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02443731 0,04169571 ! fructose metabolic process GO:0006000 20 16 0,000 0,02443731 0,0416648 ! regulation of protein binding GO:0043393 27 16 0,000 0,02443731 0,04163394 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02443731 0,04160312 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02443731 0,04157235 ! protein export from nucleus GO:0006611 24 16 0,000 0,02443731 0,04154162 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02443731 0,04151094 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02443731 0,04148031 ! DNA replication initiation GO:0006270 25 16 0,000 0,02443731 0,04144972 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02443731 0,04141917 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02443731 0,04138867 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02443731 0,04135822 ! diencephalon development GO:0021536 25 16 0,000 0,02443731 0,04132781 ! oogenesis GO:0048477 23 16 0,000 0,02443731 0,04129744 ! neural crest cell migration GO:0001755 24 16 0,000 0,02443731 0,04126712 ! G1 phase GO:0051318 27 16 0,000 0,02443731 0,04123684 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02443731 0,04120661 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02443731 0,04117642 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02443731 0,04114628 ! steroid catabolic process GO:0006706 22 16 0,000 0,02443731 0,04111618 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02443731 0,04108612 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02443731 0,04105611 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02443731 0,04102614 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02443731 0,04099622 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02443731 0,04096634 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02443731 0,0409365 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02443731 0,04090671 ! nerve development GO:0021675 18 16 0,000 0,02443731 0,04087696 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02443731 0,04084725 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02443731 0,04081759 ! negative regulation of translation GO:0017148 22 16 0,000 0,02443731 0,04078796 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0259454 0,04327368 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0259454 0,04324233 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0259454 0,04321101 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0259454 0,04317975 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0259454 0,04314852 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0259454 0,04311735 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0259454 0,04308622 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0259454 0,04305513 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0259454 0,04302409 ! signal complex assembly GO:0007172 29 17 0,000 0,0259454 0,04299309 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0259454 0,04296214 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0259454 0,04293123 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,0259454 0,04290037 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0259454 0,04286955 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0259454 0,04283877 ! memory GO:0007613 25 17 0,000 0,0259454 0,04280804 ! keratinization GO:0031424 17 17 0,000 0,0259454 0,04277735 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0259454 0,04274671 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,0259454 0,04271611 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0259454 0,04268556 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0259454 0,04265505 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0259454 0,04262458 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0259454 0,04259415 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0259454 0,04256377 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0259454 0,04253343 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0259454 0,04250314 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,0259454 0,04247289 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0259454 0,04244268 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0259454 0,04241251 ! membrane budding GO:0006900 29 17 0,000 0,0259454 0,04238239 ! heme metabolic process GO:0042168 27 17 0,000 0,0259454 0,04235231 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0259454 0,04232228 ! neuromuscular junction development GO:0007528 23 17 0,000 0,0259454 0,04229228 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0259454 0,04226233 ! body fluid secretion GO:0007589 27 17 0,000 0,0259454 0,04223242 ! stem cell differentiation GO:0048863 36 17 0,000 0,0259454 0,04220255 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0259454 0,04217273 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,0259454 0,04214294 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0259454 0,0421132 ! sensory perception of pain GO:0019233 23 17 0,000 0,0259454 0,0420835 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0259454 0,04205385 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0259454 0,04202423 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,0259454 0,04199466 ! synaptogenesis GO:0007416 24 17 0,000 0,0259454 0,04196513 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,0259454 0,04193563 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0259454 0,04190619 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0259454 0,04187678 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0259454 0,04184741 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0259454 0,04181809 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,0259454 0,0417888 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0259454 0,04175956 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0259454 0,04173036 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0259454 0,04170119 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02745123 0,04409067 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02745123 0,0440599 ! positive regulation of translation GO:0045727 28 18 0,000 0,02745123 0,04402918 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02745123 0,04399849 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02745123 0,04396785 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02745123 0,04393726 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02745123 0,0439067 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02745123 0,04387619 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02745123 0,04384572 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02745123 0,04381529 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02745123 0,04378491 ! axis specification GO:0009798 26 18 0,000 0,02745123 0,04375457 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02745123 0,04372426 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02745123 0,04369401 ! pancreas development GO:0031016 26 18 0,000 0,02745123 0,04366379 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02745123 0,04363361 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02745123 0,04360348 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02745123 0,04357339 ! response to retinoic acid GO:0032526 25 18 0,000 0,02745123 0,04354334 ! pigmentation during development GO:0048066 31 18 0,000 0,02745123 0,04351333 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02745123 0,04348336 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02745123 0,04345343 ! fucose metabolic process GO:0006004 26 18 0,000 0,02745123 0,04342355 ! response to fungus GO:0009620 19 18 0,000 0,02745123 0,0433937 ! peptide cross-linking GO:0018149 31 18 0,000 0,02745123 0,0433639 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02745123 0,04333414 ! heart process GO:0003015 27 18 0,000 0,02745123 0,04330442 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02745123 0,04327473 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02745123 0,04324509 ! visual learning GO:0008542 35 18 0,000 0,02745123 0,04321549 ! somitogenesis GO:0001756 24 18 0,000 0,02745123 0,04318594 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02745123 0,04315642 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02745123 0,04312694 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02745123 0,0430975 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02745123 0,0430681 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02745123 0,04303874 ! vitamin transport GO:0051180 24 18 0,000 0,02745123 0,04300943 ! hormone transport GO:0009914 27 18 0,000 0,02745123 0,04298015 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02745123 0,04295091 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02745123 0,04292171 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02745123 0,04289255 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02745123 0,04286343 ! cell-cell recognition GO:0009988 20 18 0,000 0,02745123 0,04283435 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02745123 0,04280531 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02745123 0,04277631 ! regulation of glucose import GO:0046324 21 18 0,000 0,02745123 0,04274735 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02745123 0,04271843 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02745123 0,04268955 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02745123 0,0426607 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02745123 0,0426319 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02895483 0,04493665 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02895483 0,04490635 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02895483 0,04487609 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02895483 0,04484587 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02895483 0,04481569 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02895483 0,04478555 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02895483 0,04475545 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02895483 0,04472539 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02895483 0,04469538 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02895483 0,0446654 ! regeneration GO:0031099 32 19 0,000 0,02895483 0,04463546 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02895483 0,04460557 ! response to alkaloid GO:0043279 32 19 0,000 0,02895483 0,04457571 ! sensory perception of taste GO:0050909 23 19 0,000 0,02895483 0,04454589 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02895483 0,04451612 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02895483 0,04448638 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02895483 0,04445668 ! peroxisome organization GO:0007031 29 19 0,000 0,02895483 0,04442703 ! digestive system process GO:0022600 30 19 0,000 0,02895483 0,04439741 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02895483 0,04436783 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02895483 0,04433829 ! response to vitamin A GO:0033189 26 19 0,000 0,02895483 0,04430879 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02895483 0,04427933 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02895483 0,04424991 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02895483 0,04422053 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02895483 0,04419118 ! response to starvation GO:0042594 30 19 0,000 0,02895483 0,04416188 ! sex determination GO:0007530 29 19 0,000 0,02895483 0,04413261 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02895483 0,04410338 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02895483 0,0440742 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02895483 0,04404505 ! cytolysis GO:0019835 20 19 0,000 0,02895483 0,04401594 ! renal system process GO:0003014 35 19 0,000 0,02895483 0,04398686 ! vasodilation GO:0042311 33 19 0,000 0,02895483 0,04395783 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02895483 0,04392883 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02895483 0,04389988 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02895483 0,04387096 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02895483 0,04384207 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02895483 0,04381323 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02895483 0,04378443 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02895483 0,04375566 ! sarcomere organization GO:0045214 23 19 0,000 0,02895483 0,04372693 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02895483 0,04369824 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02895483 0,04366958 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02895483 0,04364096 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02895483 0,04361238 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02895483 0,04358384 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02895483 0,04355534 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02895483 0,04352687 ! protein stabilization GO:0050821 26 19 0,000 0,02895483 0,04349844 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03045619 0,04572404 ! iron ion transport GO:0006826 37 20 0,000 0,03045619 0,04569422 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03045619 0,04566443 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03045619 0,04563468 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03045619 0,04560497 ! response to vitamin GO:0033273 29 20 0,000 0,03045619 0,0455753 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03045619 0,04554567 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03045619 0,04551607 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03045619 0,04548652 ! spinal cord development GO:0021510 31 20 0,000 0,03045619 0,045457 ! response to ethanol GO:0045471 37 20 0,000 0,03045619 0,04542752 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03045619 0,04539808 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03045619 0,04536868 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03045619 0,04533931 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03045619 0,04530998 ! chromosome condensation GO:0030261 31 20 0,000 0,03045619 0,04528069 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03045619 0,04525144 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03045619 0,04522223 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03045619 0,04519305 ! pallium development GO:0021543 38 20 0,000 0,03045619 0,04516392 ! DNA modification GO:0006304 28 20 0,000 0,03045619 0,04513482 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03045619 0,04510575 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03045619 0,04507673 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03045619 0,04504774 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03045619 0,04501879 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03045619 0,04498987 ! collagen catabolic process GO:0030574 25 20 0,000 0,03045619 0,044961 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03045619 0,04493216 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03045619 0,04490336 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03045619 0,04487459 ! alditol metabolic process GO:0019400 24 20 0,000 0,03045619 0,04484586 ! actin filament-based movement GO:0030048 34 20 0,000 0,03045619 0,04481717 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03195531 0,04699311 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03195531 0,04696308 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03195531 0,04693309 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03195531 0,04690314 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03195531 0,04687323 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03195531 0,04684335 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03195531 0,04681351 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03195531 0,04678372 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03195531 0,04675395 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03195531 0,04672423 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03195531 0,04669455 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03195531 0,0466649 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03195531 0,04663529 ! vesicle docking GO:0048278 27 21 0,000 0,03195531 0,04660572 ! phototransduction GO:0007602 25 21 0,000 0,03195531 0,04657618 ! dendrite development GO:0016358 35 21 0,000 0,03195531 0,04654669 ! visual behavior GO:0007632 39 21 0,000 0,03195531 0,04651723 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03195531 0,0464878 ! ovarian follicle development GO:0001541 30 21 0,000 0,03195531 0,04645842 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03195531 0,04642907 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03195531 0,04639976 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03195531 0,04637048 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03195531 0,04634125 ! cell aging GO:0007569 32 21 0,000 0,03195531 0,04631205 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03195531 0,04628288 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03195531 0,04625376 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03195531 0,04622466 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03195531 0,04619561 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03195531 0,04616659 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03195531 0,04613761 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03195531 0,04610867 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03195531 0,04607976 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03195531 0,04605089 ! fatty acid transport GO:0015908 30 21 0,000 0,03195531 0,04602205 ! immunoglobulin production GO:0002377 33 21 0,000 0,03195531 0,04599325 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03195531 0,04596449 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03195531 0,04593576 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03195531 0,04590707 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03195531 0,04587841 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03195531 0,04584979 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03195531 0,04582121 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03195531 0,04579266 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03195531 0,04576415 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03195531 0,04573567 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03195531 0,04570722 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03195531 0,04567882 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03195531 0,04565045 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03195531 0,04562211 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,0334522 0,04772957 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,0334522 0,04769998 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0334522 0,04767042 ! viral genome replication GO:0019079 29 22 0,000 0,0334522 0,04764091 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0334522 0,04761143 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,0334522 0,04758198 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0334522 0,04755257 ! molting cycle process GO:0022404 40 22 0,000 0,0334522 0,0475232 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,0334522 0,04749387 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0334522 0,04746457 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,0334522 0,04743531 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0334522 0,04740608 ! vasculogenesis GO:0001570 33 22 0,000 0,0334522 0,04737689 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,0334522 0,04734773 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,0334522 0,04731861 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,0334522 0,04728953 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0334522 0,04726048 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,0334522 0,04723147 ! lysosome organization GO:0007040 37 22 0,000 0,0334522 0,04720249 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0334522 0,04717355 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0334522 0,04714465 ! regulation of behavior GO:0050795 38 22 0,000 0,0334522 0,04711578 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0334522 0,04708694 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0334522 0,04705814 ! membrane depolarization GO:0051899 35 22 0,000 0,0334522 0,04702938 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0334522 0,04700065 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,0334522 0,04697196 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,0334522 0,0469433 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,0334522 0,04691467 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0334522 0,04688609 ! blastocyst development GO:0001824 37 22 0,000 0,0334522 0,04685753 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0334522 0,04682901 ! protein tetramerization GO:0051262 39 22 0,000 0,0334522 0,04680053 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03494686 0,04886188 ! neuron fate commitment GO:0048663 32 23 0,000 0,03494686 0,04883219 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03494686 0,04880254 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03494686 0,04877293 ! myelination GO:0042552 35 23 0,000 0,03494686 0,04874335 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03494686 0,04871381 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03494686 0,0486843 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03494686 0,04865483 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,03494686 0,0486254 ! vesicle targeting GO:0006903 32 23 0,000 0,03494686 0,048596 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03494686 0,04856664 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03494686 0,04853731 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03494686 0,04850802 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03494686 0,04847876 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03494686 0,04844954 ! interaction with host GO:0051701 37 23 0,000 0,03494686 0,04842035 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03494686 0,0483912 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03494686 0,04836209 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03494686 0,048333 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03494686 0,04830396 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03494686 0,04827495 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03494686 0,04824597 ! cell fate determination GO:0001709 45 23 0,000 0,03494686 0,04821703 ! pentose metabolic process GO:0019321 31 23 0,000 0,03494686 0,04818812 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03494686 0,04815925 ! spermatid development GO:0007286 33 23 0,000 0,03494686 0,04813041 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03494686 0,04810161 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03494686 0,04807284 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03494686 0,0480441 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,03494686 0,0480154 ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03494686 0,04798674 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03494686 0,04795811 ! regulation of amine transport GO:0051952 38 23 0,000 0,03494686 0,04792951 ! liver development GO:0001889 40 23 0,000 0,03494686 0,04790095 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,0364393 0,04991685 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,0364393 0,04988714 ! initiation of viral infection GO:0019059 42 24 0,000 0,0364393 0,04985746 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,0364393 0,04982782 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,0364393 0,04979821 ! superoxide metabolic process GO:0006801 32 24 0,000 0,0364393 0,04976864 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,0364393 0,0497391 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,0364393 0,0497096 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,0364393 0,04968014 ! sperm motility GO:0030317 27 24 0,000 0,0364393 0,0496507 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,0364393 0,04962131 ! vacuole organization GO:0007033 39 24 0,000 0,0364393 0,04959195 ! receptor metabolic process GO:0043112 37 24 0,000 0,0364393 0,04956262 ! neural crest cell development GO:0014032 39 24 0,000 0,0364393 0,04953333 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,0364393 0,04950407 ! negative regulation of cell development GO:0010721 56 24 0,000 0,0364393 0,04947485 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,0364393 0,04944566 ! base-excision repair GO:0006284 31 24 0,000 0,0364393 0,0494165 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,0364393 0,04938738 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,0364393 0,0493583 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,0364393 0,04932925 ! glutathione metabolic process GO:0006749 29 24 0,000 0,0364393 0,04930023 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,0364393 0,04927125 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,0364393 0,0492423 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,0364393 0,04921338 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03792951 0,05119594 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03792951 0,05116591 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03792951 0,05113592 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03792951 0,05110596 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03792951 0,05107604 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03792951 0,05104616 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03792951 0,0510163 ! peptide transport GO:0015833 43 25 0,000 0,03792951 0,05098649 ! male gonad development GO:0008584 33 25 0,000 0,03792951 0,05095671 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03792951 0,05092696 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03792951 0,05089725 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03792951 0,05086757 ! phospholipid transport GO:0015914 35 25 0,000 0,03792951 0,05083792 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03792951 0,05080832 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03792951 0,05077874 ! detection of light stimulus GO:0009583 30 25 0,000 0,03792951 0,0507492 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03792951 0,0507197 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03792951 0,05069023 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03792951 0,05066079 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03792951 0,05063139 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03941751 0,05258716 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03941751 0,05255667 ! translational initiation GO:0006413 43 26 0,000 0,03941751 0,05252622 ! regulation of pH GO:0006885 36 26 0,000 0,03941751 0,05249581 ! circadian rhythm GO:0007623 42 26 0,000 0,03941751 0,05246543 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03941751 0,05243509 ! post-embryonic development GO:0009791 42 26 0,000 0,03941751 0,05240478 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03941751 0,0523745 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03941751 0,05234426 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03941751 0,05231406 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03941751 0,05228389 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03941751 0,05225375 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03941751 0,05222365 ! regulation of coagulation GO:0050818 39 26 0,000 0,03941751 0,05219359 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04090328 0,05412978 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04090328 0,05409865 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04090328 0,05406756 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04090328 0,0540365 ! membrane docking GO:0022406 39 27 0,000 0,04090328 0,05400548 ! catechol metabolic process GO:0009712 43 27 0,000 0,04090328 0,0539745 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04090328 0,05394355 ! acute-phase response GO:0006953 42 27 0,000 0,04090328 0,05391264 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04090328 0,05388176 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04090328 0,05385092 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04090328 0,05382011 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04090328 0,05378934 ! natural killer cell activation GO:0030101 35 27 0,000 0,04090328 0,0537586 ! lipid oxidation GO:0034440 38 27 0,000 0,04090328 0,0537279 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04090328 0,05369723 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04090328 0,0536666 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04090328 0,053636 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04090328 0,05360544 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04090328 0,05357492 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04090328 0,05354442 ! gene silencing GO:0016458 41 27 0,000 0,04090328 0,05351397 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04238685 0,05542339 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04238685 0,0553919 ! phenol metabolic process GO:0018958 44 28 0,000 0,04238685 0,05536045 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04238685 0,05532903 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04238685 0,05529765 ! cell junction assembly GO:0034329 56 28 0,000 0,04238685 0,0552663 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04238685 0,05523499 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04238685 0,05520371 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,04238685 0,05517247 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04238685 0,05514126 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04238685 0,05511009 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04238685 0,05507895 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04238685 0,05504785 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04238685 0,05501679 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04238685 0,05498576 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04238685 0,05495476 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04238685 0,0549238 ! mesoderm formation GO:0001707 46 28 0,000 0,04238685 0,05489288 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04238685 0,05486199 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04238685 0,05483113 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04238685 0,05480031 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04238685 0,05476952 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04238685 0,05473877 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04238685 0,05470805 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04238685 0,05467737 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04238685 0,05464672 ! placenta development GO:0001890 37 28 0,000 0,04238685 0,05461611 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,0438682 0,0564932 ! regulation of innate immune response GO:0045088 38 29 0,000 0,0438682 0,05646159 ! ovulation cycle process GO:0022602 41 29 0,000 0,0438682 0,05643001 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,0438682 0,05639847 ! protein targeting to membrane GO:0006612 53 29 0,000 0,0438682 0,05636696 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,0438682 0,05633549 ! mismatch repair GO:0006298 34 29 0,000 0,0438682 0,05630405 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,0438682 0,05627265 ! formation of primary germ layer GO:0001704 48 29 0,000 0,0438682 0,05624128 ! telencephalon development GO:0021537 52 29 0,000 0,0438682 0,05620995 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,0438682 0,05617865 ! eye morphogenesis GO:0048592 51 29 0,000 0,0438682 0,05614739 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,0438682 0,05611616 ! tissue homeostasis GO:0001894 42 29 0,000 0,0438682 0,05608497 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04534735 0,05794383 ! collagen metabolic process GO:0032963 40 30 0,000 0,04534735 0,05791166 ! organic anion transport GO:0015711 51 30 0,000 0,04534735 0,05787952 ! cholesterol transport GO:0030301 46 30 0,000 0,04534735 0,05784742 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,04534735 0,05781536 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04534735 0,05778333 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04534735 0,05775133 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04534735 0,05771937 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04534735 0,05768745 ! ovulation cycle GO:0042698 43 30 0,000 0,04534735 0,05765556 ! hindbrain development GO:0030902 45 30 0,000 0,04534735 0,0576237 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04534735 0,05759188 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04534735 0,0575601 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04534735 0,05752835 ! response to heat GO:0009408 41 30 0,000 0,04534735 0,05749664 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04534735 0,05746496 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04534735 0,05743332 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04682429 0,05927126 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04682429 0,05923865 ! mammary gland development GO:0030879 57 31 0,000 0,04682429 0,05920609 ! glial cell differentiation GO:0010001 55 31 0,000 0,04682429 0,05917356 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04682429 0,05914106 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04682429 0,0591086 ! odontogenesis GO:0042476 50 31 0,000 0,04682429 0,05907618 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04682429 0,05904379 ! segmentation GO:0035282 41 31 0,000 0,04682429 0,05901144 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04682429 0,05897912 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04682429 0,05894684 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04682429 0,05891459 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04682429 0,05888238 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04682429 0,0588502 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04682429 0,05881806 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04682429 0,05878596 ! RNA modification GO:0009451 40 31 0,000 0,04682429 0,05875389 ! regulation of muscle development GO:0048634 48 32 0,000 0,04829904 0,06057131 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04829904 0,0605383 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04829904 0,06050533 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,04829904 0,06047239 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04829904 0,06043949 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04829904 0,06040662 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04829904 0,06037379 ! regulation of protein stability GO:0031647 48 32 0,000 0,04829904 0,060341 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04829904 0,06030824 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04829904 0,06027552 ! cytokine production GO:0001816 44 32 0,000 0,04829904 0,06024283 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04829904 0,06021018 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04829904 0,06017756 ! vesicle localization GO:0051648 47 32 0,000 0,04829904 0,06014498 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04977158 0,06194515 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,04977158 0,06191165 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04977158 0,06187818 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04977158 0,06184475 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04977158 0,06181136 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04977158 0,061778 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04977158 0,06174468 ! cell junction organization GO:0034330 63 33 0,000 0,04977158 0,0617114 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04977158 0,06167815 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04977158 0,06164493 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04977158 0,06161175 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04977158 0,06157861 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04977158 0,0615455 ! female gonad development GO:0008585 49 33 0,000 0,04977158 0,06151243 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04977158 0,0614794 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04977158 0,0614464 ! lipid homeostasis GO:0055088 55 33 0,000 0,04977158 0,06141343 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04977158 0,0613805 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04977158 0,06134761 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04977158 0,06131475 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04977158 0,06128193 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04977158 0,06124914 ! cytokinesis GO:0000910 52 33 0,000 0,04977158 0,06121638 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04977158 0,06118367 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05124193 0,0629575 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05124193 0,06292389 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05124193 0,06289031 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05124193 0,06285677 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05124193 0,06282327 ! feeding behavior GO:0007631 45 34 0,000 0,05124193 0,0627898 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05124193 0,06275636 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05124193 0,06272296 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05124193 0,0626896 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05124193 0,06265627 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05124193 0,06262298 ! neuron migration GO:0001764 46 34 0,000 0,05124193 0,06258972 ! female gamete generation GO:0007292 43 34 0,000 0,05124193 0,0625565 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05124193 0,06252331 ! polyol metabolic process GO:0019751 44 34 0,000 0,05124193 0,06249016 ! aerobic respiration GO:0009060 47 34 0,000 0,05124193 0,06245705 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05124193 0,06242397 ! embryonic organ development GO:0048568 45 34 0,000 0,05124193 0,06239092 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05124193 0,06235791 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05271009 0,06411064 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05271009 0,06407675 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05271009 0,0640429 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05271009 0,06400909 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05271009 0,06397531 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,05271009 0,06394157 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05271009 0,06390786 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05271009 0,06387419 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05271009 0,06384056 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05271009 0,06380696 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05271009 0,06377339 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05271009 0,06373986 ! pigment metabolic process GO:0042440 61 35 0,000 0,05271009 0,06370637 ! protein homooligomerization GO:0051260 52 35 0,000 0,05271009 0,06367291 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05417607 0,06540942 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05417607 0,06537511 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05417607 0,06534083 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05417607 0,06530658 ! negative regulation of binding GO:0051100 58 36 0,000 0,05417607 0,06527237 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05417607 0,0652382 ! tissue remodeling GO:0048771 62 36 0,000 0,05417607 0,06520406 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05417607 0,06516996 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05417607 0,06513589 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05417607 0,06510186 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05417607 0,06506786 ! glucan metabolic process GO:0044042 49 36 0,000 0,05417607 0,0650339 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05563986 0,06675622 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05563986 0,06672141 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05563986 0,06668664 ! learning GO:0007612 67 37 0,000 0,05563986 0,06665191 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05563986 0,06661721 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05563986 0,06658255 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05563986 0,06654793 ! amino acid activation GO:0043038 52 37 0,000 0,05563986 0,06651334 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05563986 0,06647879 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05710146 0,0681897 ! gliogenesis GO:0042063 71 38 0,000 0,05710146 0,06815431 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05710146 0,06811896 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05710146 0,06808365 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05710146 0,06804837 ! phagocytosis GO:0006909 60 38 0,000 0,05710146 0,06801313 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05710146 0,06797793 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05710146 0,06794276 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05710146 0,06790763 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05856089 0,06960726 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05856089 0,0695713 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05856089 0,06953539 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,05856089 0,06949951 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,05856089 0,06946366 ! male sex differentiation GO:0046661 53 39 0,000 0,05856089 0,06942786 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05856089 0,06939209 ! chromatin remodeling GO:0006338 68 39 0,000 0,05856089 0,06935636 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05856089 0,06932066 ! JNK cascade GO:0007254 54 39 0,000 0,05856089 0,069285 ! developmental growth GO:0048589 62 39 0,000 0,05856089 0,06924938 ! cell growth GO:0016049 61 39 0,000 0,05856089 0,0692138 ! synapse organization GO:0050808 55 39 0,000 0,05856089 0,06917825 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06001814 0,07086331 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06001814 0,07082695 ! regulation of tube size GO:0035150 60 40 0,000 0,06001814 0,07079063 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06001814 0,07075434 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06001814 0,0707181 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06001814 0,07068189 ! peptide metabolic process GO:0006518 56 40 0,000 0,06001814 0,07064571 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06001814 0,07060958 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06001814 0,07057348 ! double-strand break repair GO:0006302 67 40 0,000 0,06001814 0,07053742 ! B cell differentiation GO:0030183 62 40 0,000 0,06001814 0,07050139 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,06001814 0,0704654 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06001814 0,07042945 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,06001814 0,07039354 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06001814 0,07035766 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,06147322 0,0720267 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06147322 0,07199003 ! glucose transport GO:0015758 52 41 0,000 0,06147322 0,07195339 ! endosome transport GO:0016197 71 41 0,000 0,06147322 0,07191679 ! striated muscle contraction GO:0006941 62 41 0,000 0,06147322 0,07188023 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06147322 0,0718437 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06147322 0,07180722 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06147322 0,07177077 ! biopolymer methylation GO:0043414 62 41 0,000 0,06147322 0,07173435 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06147322 0,07169798 ! mitochondrial transport GO:0006839 60 42 0,000 0,06292613 0,07335535 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06292613 0,07331819 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06292613 0,07328107 ! cellular component disassembly GO:0022411 64 42 0,000 0,06292613 0,07324398 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06292613 0,07320693 ! hexose transport GO:0008645 54 42 0,000 0,06292613 0,07316992 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06292613 0,07313295 ! excretion GO:0007588 63 42 0,000 0,06292613 0,07309601 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06292613 0,07305911 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06292613 0,07302225 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06292613 0,07298543 ! regulation of cell shape GO:0008360 78 42 0,000 0,06292613 0,07294864 ! positive regulation of binding GO:0051099 59 43 0,000 0,06437688 0,07459286 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06437688 0,0745553 ! leukocyte migration GO:0050900 60 43 0,000 0,06437688 0,07451778 ! neuromuscular process GO:0050905 79 43 0,000 0,06437688 0,07448029 ! activation of caspase activity GO:0006919 65 43 0,000 0,06437688 0,07444285 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06437688 0,07440544 ! tRNA processing GO:0008033 49 43 0,000 0,06437688 0,07436807 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06437688 0,07433073 ! vesicle organization GO:0016050 79 43 0,000 0,06437688 0,07429344 ! methylation GO:0032259 64 43 0,000 0,06437688 0,07425618 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,06582546 0,075889 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,06582546 0,07585098 ! glycolysis GO:0006096 53 44 0,000 0,06582546 0,075813 ! regulation of action potential GO:0001508 71 44 0,000 0,06582546 0,07577505 ! regulation of ion transport GO:0043269 57 44 0,000 0,06582546 0,07573715 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,06582546 0,07569928 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,06582546 0,07566145 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,06582546 0,07562366 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,06582546 0,0755859 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,06582546 0,07554818 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,06582546 0,0755105 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,06582546 0,07547286 ! RNA catabolic process GO:0006401 64 45 0,000 0,06727188 0,07709284 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06727188 0,07705445 ! regulation of translational initiation GO:0006446 64 45 0,000 0,06727188 0,07701609 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06727188 0,07697778 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06727188 0,0769395 ! cell recognition GO:0008037 58 45 0,000 0,06727188 0,07690126 ! cell maturation GO:0048469 60 45 0,000 0,06727188 0,07686306 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06727188 0,07682489 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,06871615 0,07843531 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,06871615 0,0783964 ! cell redox homeostasis GO:0045454 63 46 0,000 0,06871615 0,07835753 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,06871615 0,0783187 ! regulation of ossification GO:0030278 71 46 0,000 0,06871615 0,07827991 ! histone modification GO:0016570 68 46 0,000 0,06871615 0,07824116 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,06871615 0,07820245 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07015826 0,07980415 ! viral infectious cycle GO:0019058 71 47 0,000 0,07015826 0,07976471 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07015826 0,0797253 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07015826 0,07968593 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07015826 0,07964659 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07015826 0,0796073 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07015826 0,07956805 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07015826 0,07952883 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07015826 0,07948965 ! chloride transport GO:0006821 67 48 0,000 0,07159822 0,0810812 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07159822 0,08104129 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07159822 0,08100143 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07159822 0,08096161 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07159822 0,08092182 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,07159822 0,08088208 ! gastrulation GO:0007369 73 48 0,000 0,07159822 0,08084237 ! heart morphogenesis GO:0003007 65 48 0,000 0,07159822 0,0808027 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,07159822 0,08076308 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07159822 0,08072349 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07159822 0,08068393 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07159822 0,08064442 ! nuclear export GO:0051168 69 48 0,000 0,07159822 0,08060495 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07159822 0,08056551 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07159822 0,08052612 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07303604 0,08210307 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07303604 0,08206296 ! sensory perception of smell GO:0007608 61 49 0,000 0,07303604 0,08202289 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07303604 0,08198286 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07303604 0,08194287 ! RNA elongation GO:0006354 62 49 0,000 0,07303604 0,08190292 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07303604 0,081863 ! germ cell development GO:0007281 68 49 0,000 0,07303604 0,08182313 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07303604 0,08178329 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07303604 0,0817435 ! cartilage development GO:0051216 70 49 0,000 0,07303604 0,08170374 ! maintenance of location GO:0051235 84 49 0,000 0,07303604 0,08166402 ! regulation of actin filament length GO:0030832 72 50 0,000 0,07447171 0,08322883 ! membrane fusion GO:0006944 80 50 0,000 0,07447171 0,0831884 ! lipid modification GO:0030258 73 50 0,000 0,07447171 0,08314802 ! positive regulation of growth GO:0045927 67 50 0,000 0,07447171 0,08310768 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07447171 0,08306737 ! proton transport GO:0015992 75 50 0,000 0,07447171 0,08302711 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07447171 0,08298688 ! positive regulation of secretion GO:0051047 71 51 0,000 0,07590523 0,08454336 ! hydrogen transport GO:0006818 77 51 0,000 0,07590523 0,08450244 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,07590523 0,08446156 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,07590523 0,08442071 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,07590523 0,08437991 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,07590523 0,08433915 ! adult behavior GO:0030534 80 51 0,000 0,07590523 0,08429842 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,07590523 0,08425774 ! transition metal ion transport GO:0000041 74 52 0,000 0,07733662 0,08580523 ! regulation of cellular component size GO:0032535 74 52 0,000 0,07733662 0,08576385 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,07733662 0,08572252 ! aging GO:0007568 79 52 0,000 0,07733662 0,08568123 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,07733662 0,08563998 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,07733662 0,08559877 ! establishment of organelle localization GO:0051656 85 52 0,000 0,07733662 0,08555759 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,07876588 0,08709688 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,07876588 0,08705503 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,07876588 0,08701322 ! cell projection assembly GO:0030031 76 53 0,000 0,07876588 0,08697145 ! amino acid transport GO:0006865 84 54 0,000 0,080193 0,08850475 ! regulation of mitosis GO:0007088 84 54 0,000 0,080193 0,0884623 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,080193 0,0884199 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,080193 0,08837753 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,080193 0,0883352 ! DNA catabolic process GO:0006308 67 54 0,000 0,080193 0,08829292 ! detection of external stimulus GO:0009581 66 54 0,000 0,080193 0,08825067 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,080193 0,08820847 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,080193 0,0881663 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,080193 0,08812418 ! exocytosis GO:0006887 74 55 0,000 0,08161799 0,08964727 ! mesoderm development GO:0007498 76 55 0,000 0,08161799 0,08960448 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08161799 0,08956173 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08161799 0,08951902 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,08304086 0,09103622 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,08304086 0,09099285 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,08304086 0,09094952 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,08304086 0,09090623 ! carbohydrate transport GO:0008643 74 57 0,000 0,08446161 0,09241755 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,08446161 0,09237361 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,08446161 0,0923297 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,08446161 0,09228584 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,08446161 0,09224202 ! camera-type eye development GO:0043010 88 57 0,000 0,08446161 0,09219824 ! secondary metabolic process GO:0019748 84 57 0,000 0,08446161 0,0921545 ! developmental maturation GO:0021700 75 57 0,000 0,08446161 0,09211081 ! gonad development GO:0008406 79 57 0,000 0,08446161 0,09206715 ! viral reproductive process GO:0022415 87 58 0,000 0,08588023 0,09356918 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,08588023 0,09352487 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,08588023 0,09348061 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,08588023 0,09343639 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,08729674 0,09493262 ! activation of MAPK activity GO:0000187 84 59 0,000 0,08729674 0,09488776 ! lung development GO:0030324 94 59 0,000 0,08729674 0,09484294 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,08729674 0,09479816 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,08729674 0,09475342 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,08871113 0,09624321 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,08871113 0,09619783 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,08871113 0,0961525 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,08871113 0,09610721 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,08871113 0,09606196 ! regulation of heart contraction GO:0008016 91 60 0,000 0,08871113 0,09601676 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,08871113 0,09597159 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09012342 0,09745362 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09012342 0,09740783 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,09012342 0,09736208 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09012342 0,09731637 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09012342 0,0972707 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09012342 0,09722507 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09012342 0,09717949 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,09153359 0,09865383 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09153359 0,09860762 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09153359 0,09856145 ! respiratory tube development GO:0030323 99 62 0,000 0,09153359 0,09851533 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,09153359 0,09846925 ! organelle localization GO:0051640 96 62 0,000 0,09153359 0,09842322 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09294166 0,09989057 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09294166 0,09984392 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09294166 0,0997973 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09294166 0,09975074 ! viral reproduction GO:0016032 92 63 0,000 0,09294166 0,09970421 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09294166 0,09965773 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,09434763 0,10111815 ! appendage morphogenesis GO:0035107 93 64 0,000 0,09434763 0,10107105 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,09434763 0,101024 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,09434763 0,10097699 ! hexose catabolic process GO:0019320 82 64 0,000 0,09434763 0,10093003 ! respiratory system development GO:0060541 100 64 0,000 0,09434763 0,1008831 ! adaptive immune response GO:0002250 94 64 0,000 0,09434763 0,10083622 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,0957515 0,10228911 ! regulation of caspase activity GO:0043281 97 65 0,000 0,0957515 0,10224162 ! appendage development GO:0048736 94 65 0,000 0,0957515 0,10219418 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,0957515 0,10214678 ! defense response to bacterium GO:0042742 73 65 0,000 0,0957515 0,10209942 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,0957515 0,10205211 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,0957515 0,10200484 ! activation of immune response GO:0002253 83 65 0,000 0,0957515 0,10195762 ! protein oligomerization GO:0051259 100 65 0,000 0,0957515 0,10191044 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,09715328 0,10335455 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,09715328 0,10330677 ! antigen processing and presentation GO:0019882 96 66 0,000 0,09715328 0,10325903 ! axon guidance GO:0007411 99 66 0,000 0,09715328 0,10321133 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,09715328 0,10316368 ! regulation of immune effector process GO:0002697 101 66 0,000 0,09715328 0,10311608 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,09855296 0,10455342 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,09855296 0,10450521 ! acute inflammatory response GO:0002526 92 68 0,000 0,09995055 0,10593837 ! learning or memory GO:0007611 123 68 0,000 0,09995055 0,10588958 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,09995055 0,10584082 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,09995055 0,10579212 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,09995055 0,10574345 ! rhythmic process GO:0048511 105 68 0,000 0,09995055 0,10569484 ! inorganic anion transport GO:0015698 93 68 0,000 0,09995055 0,10564626 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10134606 0,10707209 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10134606 0,10702293 ! response to drug GO:0042493 108 69 0,000 0,10134606 0,10697381 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10273948 0,10839486 ! humoral immune response GO:0006959 86 70 0,000 0,10273948 0,10834516 ! eye development GO:0001654 111 70 0,000 0,10273948 0,10829551 ! amine transport GO:0015837 101 70 0,000 0,10273948 0,1082459 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10273948 0,10819634 ! regulation of catabolic process GO:0009894 106 70 0,000 0,10273948 0,10814682 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,10413082 0,10956125 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,10413082 0,10951115 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,10413082 0,1094611 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,10413082 0,1094111 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,10552008 0,11082018 ! response to hypoxia GO:0001666 132 72 0,000 0,10552008 0,1107696 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,10552008 0,11071907 ! negative regulation of transport GO:0051051 116 73 0,000 0,10690727 0,11212345 ! regulation of blood pressure GO:0008217 107 73 0,000 0,10690727 0,11207235 ! mitochondrion organization GO:0007005 104 73 0,000 0,10690727 0,11202129 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,10690727 0,11197028 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,10829239 0,11336937 ! response to oxygen levels GO:0070482 137 74 0,000 0,10829239 0,11331779 ! digestion GO:0007586 97 74 0,000 0,10829239 0,11326626 ! protein import into nucleus GO:0006606 118 74 0,000 0,10829239 0,11321477 ! blood coagulation GO:0007596 116 75 0,000 0,10967544 0,11460859 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,10967544 0,11455654 ! nuclear import GO:0051170 121 75 0,000 0,10967544 0,11450454 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,10967544 0,11445259 ! amine biosynthetic process GO:0009309 97 76 0,000 0,11105642 0,11584116 ! tRNA metabolic process GO:0006399 95 76 0,000 0,11105642 0,11578865 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,11105642 0,11573619 ! regulation of protein transport GO:0051223 114 76 0,000 0,11105642 0,11568377 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,11243534 0,11706713 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,11243534 0,11701416 ! regulation of DNA binding GO:0051101 119 77 0,000 0,11243534 0,11696123 ! sex differentiation GO:0007548 105 77 0,000 0,11243534 0,11690836 ! protein ubiquitination GO:0016567 125 77 0,000 0,11243534 0,11685553 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,11243534 0,11680275 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,11243534 0,11675002 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,11243534 0,11669733 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,1138122 0,1180731 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,1138122 0,11801987 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,115187 0,11939167 ! cellular respiration GO:0045333 107 79 0,000 0,115187 0,11933789 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,115187 0,11928415 ! T cell activation GO:0042110 134 79 0,000 0,115187 0,11923047 ! regulation of lyase activity GO:0051339 133 79 0,000 0,115187 0,11917684 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,115187 0,11912325 ! chromatin assembly GO:0031497 102 80 0,000 0,11655975 0,12048873 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,11655975 0,1204346 ! protein localization in nucleus GO:0034504 133 80 0,000 0,11655975 0,12038053 ! forebrain development GO:0030900 131 80 0,000 0,11655975 0,12032649 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,11793045 0,12168687 ! hemostasis GO:0007599 125 81 0,000 0,11793045 0,1216323 ! mRNA transport GO:0051028 121 81 0,000 0,11793045 0,12157778 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,11793045 0,12152331 ! regulation of neurological system process GO:0031644 122 81 0,000 0,11793045 0,12146889 ! vitamin metabolic process GO:0006766 103 81 0,000 0,11793045 0,12141452 ! ossification GO:0001503 134 82 0,000 0,1192991 0,12276865 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1192991 0,12271374 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12066571 0,12406398 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12066571 0,12400854 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,12066571 0,12395316 ! regulation of defense response GO:0031347 117 84 0,000 0,12203027 0,12529894 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,12203027 0,12524302 ! sterol metabolic process GO:0016125 120 84 0,000 0,12203027 0,12518716 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,12339279 0,1265285 ! rRNA metabolic process GO:0016072 107 85 0,000 0,12339279 0,12647211 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,12339279 0,12641578 ! transcription initiation GO:0006352 118 85 0,000 0,12339279 0,12635949 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,12339279 0,12630326 ! regulation of protein localization GO:0032880 132 85 0,000 0,12339279 0,12624707 ! regulation of membrane potential GO:0042391 128 85 0,000 0,12339279 0,12619094 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,12339279 0,12613485 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,12475328 0,12746892 ! nucleosome organization GO:0034728 114 87 0,000 0,12611173 0,12879973 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,12611173 0,12874256 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,12611173 0,12868544 ! female pregnancy GO:0007565 130 87 0,000 0,12611173 0,12862837 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,12611173 0,12857136 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,12746816 0,12989666 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,12746816 0,12983913 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,12746816 0,12978165 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,12746816 0,12972423 ! reproductive developmental process GO:0003006 127 89 0,000 0,12882255 0,13104461 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,12882255 0,13098668 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,12882255 0,1309288 ! regulation of T cell activation GO:0050863 128 89 0,000 0,12882255 0,13087097 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13017492 0,13218646 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13017492 0,13212812 ! hormone metabolic process GO:0042445 121 90 0,000 0,13017492 0,13206984 ! RNA localization GO:0006403 135 91 0,000 0,13152527 0,13338101 ! ATP metabolic process GO:0046034 137 91 0,000 0,13152527 0,13332222 ! response to virus GO:0009615 122 91 0,000 0,13152527 0,13326349 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,1328736 0,13457036 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,1328736 0,13451113 ! positive regulation of immune response GO:0050778 121 92 0,000 0,1328736 0,13445195 ! DNA recombination GO:0006310 146 92 0,000 0,1328736 0,13439283 ! sulfur metabolic process GO:0006790 118 92 0,000 0,1328736 0,13433375 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,13421992 0,13563524 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,13421992 0,13557567 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,13421992 0,13551616 ! electron transport chain GO:0022900 123 94 0,000 0,13556422 0,13681338 ! response to oxidative stress GO:0006979 141 94 0,000 0,13556422 0,13675338 ! regulation of binding GO:0051098 151 95 0,000 0,13690651 0,1380469 ! angiogenesis GO:0001525 149 95 0,000 0,13690651 0,1379864 ! carboxylic acid transport GO:0046942 147 95 0,000 0,13690651 0,13792596 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,13824679 0,13921525 ! in utero embryonic development GO:0001701 147 96 0,000 0,13824679 0,13915432 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,13824679 0,13909345 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,13824679 0,13903263 ! protein maturation GO:0051604 129 96 0,000 0,13824679 0,13897187 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,13958507 0,14025586 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,13958507 0,14019462 ! calcium ion transport GO:0006816 167 99 0,000 0,14225563 0,14281447 ! extracellular structure organization GO:0043062 156 99 0,000 0,14225563 0,14275216 ! protein import GO:0017038 156 99 0,000 0,14225563 0,14268991 ! regulation of translation GO:0006417 151 100 0,000 0,14358792 0,14396347 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,14358792 0,14390075 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,14358792 0,14383807 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,14358792 0,14377545 ! divalent metal ion transport GO:0070838 171 100 0,000 0,14358792 0,14371289 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,14358792 0,14365037 ! protein localization in organelle GO:0033365 161 100 0,000 0,14358792 0,14358792