pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/7013-8-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,491E-07 8,4E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 2,236E-06 2,69E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,738E-06 2,196E-03 ! interphase GO:0051325 213 98 3,000 3,1E-06 1,865E-03 ! skeletal myofibril assembly GO:0014866 10 5 1,000 1,023E-05 4,925E-03 ! muscle cell migration GO:0014812 8 5 1,000 1,023E-05 4,104E-03 ! regulation of telomerase activity GO:0051972 6 5 1,000 1,023E-05 3,518E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,455E-05 4,375E-03 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,989E-05 5,316E-03 ! negative regulation of telomere maintenance GO:0032205 11 7 1,000 2,146E-05 5,164E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 2,146E-05 4,695E-03 ! response to UV GO:0009411 104 53 2,000 2,234E-05 4,479E-03 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,638E-05 4,882E-03 ! muscle fiber development GO:0048747 112 57 2,000 2,782E-05 4,782E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,86E-05 4,587E-03 ! induction of an organ GO:0001759 14 9 1,000 3,675E-05 5,526E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 3,675E-05 5,201E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,59E-05 6,136E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,59E-05 5,813E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 4,729E-05 5,689E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 4,941E-05 5,661E-03 ! thyroid gland development GO:0030878 26 11 1,000 5,607E-05 6,132E-03 ! thymus development GO:0048538 27 11 1,000 5,607E-05 5,865E-03 ! developmental induction GO:0031128 19 11 1,000 5,607E-05 5,621E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 5,612E-05 5,401E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 5,612E-05 5,193E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 5,612E-05 5,001E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,724E-05 5,778E-03 ! positive regulation of ligase activity GO:0051351 124 77 2,000 6,86E-05 5,691E-03 ! negative regulation of organelle organization GO:0010639 161 78 2,000 7,129E-05 5,717E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 7,405E-05 5,747E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 8,892E-05 6,686E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 9,259E-05 6,751E-03 GO:0060675|ureteric bud morphogenesis, ! tube morphogenesis GO:0035239 176 86 2,000 9,537E-05 6,749E-03 ! phospholipid catabolic process GO:0009395 22 15 1,000 1,068E-04 7,339E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 1,203E-04 8,043E-03 GO:0010498|proteasomal protein catabolic process, ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,381E-04 8,981E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,381E-04 8,745E-03 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,448E-04 8,936E-03 GO:0060538|skeletal muscle organ development, ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,734E-04 0,01043197 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 2,127E-04 0,0124827 ! ureteric bud development GO:0001657 43 22 1,000 2,338E-04 0,01339545 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,338E-04 0,01308393 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,338E-04 0,01278656 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,79E-04 0,0149188 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,79E-04 0,01459448 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,031E-04 0,01551609 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,031E-04 0,01519284 ! telomere organization GO:0032200 43 25 1,000 3,031E-04 0,01488278 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 1,000 3,031E-04 0,01458512 GO:0060606|tube closure, ! tube lumen formation GO:0035148 50 26 1,000 3,281E-04 0,0154808 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 3,281E-04 0,01518309 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,281E-04 0,01489662 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,542E-04 0,01578029 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,542E-04 0,01549338 ! fat cell differentiation GO:0045444 50 27 1,000 3,542E-04 0,01521671 ! primary neural tube formation GO:0014020 51 27 1,000 3,542E-04 0,01494975 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,542E-04 0,014692 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 3,542E-04 0,01444298 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,812E-04 0,01528494 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 4,091E-04 0,01613767 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,091E-04 0,01587739 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,091E-04 0,01562537 ! myofibril assembly GO:0030239 47 30 1,000 4,381E-04 0,01646931 GO:0055002|striated muscle cell development, ! regulation of B cell activation GO:0050864 50 30 1,000 4,381E-04 0,01621594 ! inner ear morphogenesis GO:0042472 47 31 1,000 4,68E-04 0,0170607 ! spindle organization GO:0007051 46 32 1,000 4,989E-04 0,01791498 ! metanephros development GO:0001656 74 32 1,000 4,989E-04 0,01765152 ! muscle cell development GO:0055001 49 32 1,000 4,989E-04 0,0173957 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 4,989E-04 0,01714719 ! cell fate specification GO:0001708 52 33 1,000 5,307E-04 0,01798484 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,973E-04 0,01995991 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 5,973E-04 0,01968649 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,973E-04 0,01942045 ! neural tube formation GO:0001841 67 35 1,000 5,973E-04 0,01916151 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 6,32E-04 0,02000887 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 6,677E-04 0,02086416 ! meiosis I GO:0007127 65 37 1,000 6,677E-04 0,02059667 ! actomyosin structure organization GO:0031032 62 37 1,000 6,677E-04 0,02033595 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 6,677E-04 0,02008175 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 7,044E-04 0,02092229 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 7,044E-04 0,02066714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 7,42E-04 0,02150804 ! epithelial cell differentiation GO:0030855 79 43 1,000 9,019E-04 0,02583187 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 9,019E-04 0,02552797 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 9,019E-04 0,02523113 ! striated muscle cell differentiation GO:0051146 82 43 1,000 9,019E-04 0,02494112 ! neural tube development GO:0021915 77 43 1,000 9,019E-04 0,0246577 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 9,875E-04 0,02669538 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 9,875E-04 0,02639876 ! response to insulin stimulus GO:0032868 95 46 1,000 1,032E-03 0,02727794 ! response to calcium ion GO:0051592 81 47 1,000 1,077E-03 0,02816257 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,123E-03 0,02905243 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 1,123E-03 0,02874336 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 1,123E-03 0,0284408 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,123E-03 0,02814454 ! endocrine system development GO:0035270 104 49 1,000 1,17E-03 0,02902109 ! inner ear development GO:0048839 79 50 1,000 1,218E-03 0,02990267 ! embryonic skeletal system development GO:0048706 85 51 1,000 1,267E-03 0,03078908 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,267E-03 0,03048119 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! morphogenesis of a branching structure GO:0001763 111 52 1,000 1,317E-03 0,03136648 ! regulation of protein polymerization GO:0032271 103 53 1,000 1,367E-03 0,0322563 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 1,419E-03 0,03315048 ! regulation of DNA replication GO:0006275 101 56 1,000 1,525E-03 0,03528732 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,691E-03 0,03875769 ! kidney development GO:0001822 122 60 1,000 1,749E-03 0,0396905 ! regulation of protein complex assembly GO:0043254 117 61 1,000 1,807E-03 0,04062641 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,807E-03 0,04025024 ! ear development GO:0043583 103 62 1,000 1,866E-03 0,04118397 ! regulation of homeostatic process GO:0032844 134 62 1,000 1,866E-03 0,04080957 ! single fertilization GO:0007338 75 64 1,000 1,987E-03 0,04306008 ! actin filament organization GO:0007015 148 66 1,000 2,111E-03 0,04534826 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 2,175E-03 0,0463003 ! negative regulation of cell growth GO:0030308 132 67 1,000 2,175E-03 0,04589416 ! negative regulation of kinase activity GO:0033673 131 68 1,000 2,239E-03 0,04684373 ! negative regulation of cell size GO:0045792 134 69 1,000 2,304E-03 0,04779558 ! urogenital system development GO:0001655 137 69 1,000 2,304E-03 0,04738707 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 2,506E-03 0,0510932 ! fertilization GO:0009566 90 73 1,000 2,575E-03 0,05205768 ! meiosis GO:0007126 121 74 1,000 2,645E-03 0,05302394 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 2,715E-03 0,05399188 ! meiotic cell cycle GO:0051321 122 75 1,000 2,715E-03 0,05354933 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,859E-03 0,05593254 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 3,007E-03 0,05834585 ! response to metal ion GO:0010038 140 80 1,000 3,082E-03 0,05932521 ! muscle cell differentiation GO:0042692 159 80 1,000 3,082E-03 0,05885438 ! cellular lipid catabolic process GO:0044242 134 80 1,000 3,082E-03 0,05839096 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 3,158E-03 0,05936351 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 1,000 3,158E-03 0,05890333 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 3,235E-03 0,05987319 ! negative regulation of growth GO:0045926 155 84 1,000 3,391E-03 0,06228848 ! response to unfolded protein GO:0006986 131 85 1,000 3,471E-03 0,06326569 ! positive regulation of cell activation GO:0050867 145 85 1,000 3,471E-03 0,06279001 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 3,551E-03 0,0637645 ! positive regulation of protein modification process GO:0031401 136 88 1,000 3,715E-03 0,06620327 ! gland development GO:0048732 206 88 1,000 3,715E-03 0,06571648 ! response to protein stimulus GO:0051789 149 91 1,000 3,966E-03 0,06965335 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 4,492E-03 0,07832091 ! cell cycle arrest GO:0007050 213 100 1,000 4,767E-03 0,08250914 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 5,136E-03 0,08827187 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,136E-03 0,08764582 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,136E-03 0,0870286 ! positive regulation of helicase activity GO:0051096 11 5 0,000 5,136E-03 0,08642001 ! neuron fate determination GO:0048664 7 5 0,000 5,136E-03 0,08581987 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,136E-03 0,08522801 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 5,136E-03 0,08464425 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,136E-03 0,08406844 ! polyol transport GO:0015791 12 5 0,000 5,136E-03 0,08350041 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 5,136E-03 0,08294001 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,136E-03 0,08238707 ! response to superoxide GO:0000303 10 5 0,000 5,136E-03 0,08184146 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,136E-03 0,08130303 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 5,136E-03 0,08077164 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 5,136E-03 0,08024715 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,136E-03 0,07972943 ! female meiosis GO:0007143 7 5 0,000 5,136E-03 0,07921834 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,136E-03 0,07871377 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,136E-03 0,07821558 ! cobalt ion transport GO:0006824 11 5 0,000 5,136E-03 0,07772366 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 5,136E-03 0,07723788 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 5,136E-03 0,07675814 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 5,136E-03 0,07628433 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,136E-03 0,07581633 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,136E-03 0,07535403 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 5,136E-03 0,07489734 ! embryonic camera-type eye development GO:0031076 10 5 0,000 5,136E-03 0,07444615 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,136E-03 0,07400037 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 5,136E-03 0,07355989 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 5,136E-03 0,07312462 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,136E-03 0,07269448 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,136E-03 0,07226936 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,136E-03 0,07184919 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 5,136E-03 0,07143388 ! negative chemotaxis GO:0050919 14 5 0,000 5,136E-03 0,07102334 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,136E-03 0,07061749 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,136E-03 0,07021626 ! sensory perception of bitter taste GO:0050913 7 5 0,000 5,136E-03 0,06981955 ! behavioral response to pain GO:0048266 9 5 0,000 5,136E-03 0,06942731 ! clathrin coat assembly GO:0048268 14 5 0,000 5,136E-03 0,06903945 ! Notch receptor processing GO:0007220 8 5 0,000 5,136E-03 0,0686559 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,136E-03 0,06827658 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,136E-03 0,06790143 ! micturition GO:0060073 9 5 0,000 5,136E-03 0,06753039 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,136E-03 0,06716338 ! copulation GO:0007620 9 5 0,000 5,136E-03 0,06680033 ! glial cell fate commitment GO:0021781 13 5 0,000 5,136E-03 0,06644119 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,136E-03 0,06608589 ! spermidine metabolic process GO:0008216 7 5 0,000 5,136E-03 0,06573437 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,136E-03 0,06538657 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,136E-03 0,06504243 ! apoptotic cell clearance GO:0043277 20 5 0,000 5,136E-03 0,06470189 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,136E-03 0,0643649 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,136E-03 0,0640314 ! grooming behavior GO:0007625 6 5 0,000 5,136E-03 0,06370135 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,136E-03 0,06337467 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 5,136E-03 0,06305133 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,136E-03 0,06273127 ! response to protozoan GO:0001562 10 5 0,000 5,136E-03 0,06241445 ! positive regulation of glycolysis GO:0045821 14 5 0,000 5,136E-03 0,06210081 ! lymph vessel development GO:0001945 10 5 0,000 5,136E-03 0,06179031 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 5,136E-03 0,06148289 ! endochondral ossification GO:0001958 16 5 0,000 5,136E-03 0,06117852 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,136E-03 0,06087715 ! parathyroid gland development GO:0060017 13 5 0,000 5,136E-03 0,06057873 ! anagen GO:0042640 6 5 0,000 5,136E-03 0,06028323 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,136E-03 0,05999059 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,136E-03 0,05970078 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 5,136E-03 0,05941376 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 5,136E-03 0,05912948 ! dorsal spinal cord development GO:0021516 7 5 0,000 5,136E-03 0,05884791 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 5,136E-03 0,05856901 ! sphingoid catabolic process GO:0046521 6 5 0,000 5,136E-03 0,05829274 ! smooth muscle tissue development GO:0048745 28 5 0,000 5,136E-03 0,05801907 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,136E-03 0,05774795 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,136E-03 0,05747935 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,136E-03 0,05721325 ! cardiac muscle fiber development GO:0048739 10 5 0,000 5,136E-03 0,05694959 ! transepithelial chloride transport GO:0030321 9 5 0,000 5,136E-03 0,05668835 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,136E-03 0,0564295 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 5,136E-03 0,05617301 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 5,136E-03 0,05591883 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,136E-03 0,05566694 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,136E-03 0,05541731 ! histidine catabolic process GO:0006548 6 5 0,000 5,136E-03 0,05516992 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 5,136E-03 0,05492472 ! microvillus organization GO:0032528 7 5 0,000 5,136E-03 0,05468169 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 5,136E-03 0,0544408 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,136E-03 0,05420202 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,136E-03 0,05396533 ! tryptophan metabolic process GO:0006568 9 5 0,000 5,136E-03 0,0537307 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 5,136E-03 0,0534981 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,136E-03 0,05326751 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 5,136E-03 0,05303889 ! polyol catabolic process GO:0046174 7 5 0,000 5,136E-03 0,05281223 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,136E-03 0,05258749 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,136E-03 0,05236467 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,136E-03 0,05214372 ! mitochondrial fission GO:0000266 8 5 0,000 5,136E-03 0,05192463 ! sister chromatid cohesion GO:0007062 12 5 0,000 5,136E-03 0,05170737 ! mRNA transcription GO:0009299 9 5 0,000 5,136E-03 0,05149192 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 5,136E-03 0,05127826 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 5,136E-03 0,05106637 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 5,136E-03 0,05085622 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,136E-03 0,05064779 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,136E-03 0,05044107 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,136E-03 0,05023602 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,136E-03 0,05003264 ! response to food GO:0032094 6 5 0,000 5,136E-03 0,04983089 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,136E-03 0,04963077 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,136E-03 0,04943224 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 5,136E-03 0,0492353 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,136E-03 0,04903993 ! paraxial mesoderm development GO:0048339 14 5 0,000 5,136E-03 0,04884609 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 5,136E-03 0,04865378 ! forebrain neuron development GO:0021884 13 5 0,000 5,136E-03 0,04846298 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,136E-03 0,04827368 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 5,136E-03 0,04808584 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,136E-03 0,04789946 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,136E-03 0,04771452 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,136E-03 0,047531 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 5,136E-03 0,04734889 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,136E-03 0,04716817 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 5,136E-03 0,04698883 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 5,136E-03 0,04681084 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,136E-03 0,04663419 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 5,136E-03 0,04645888 ! basic amino acid transport GO:0015802 11 5 0,000 5,136E-03 0,04628487 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,136E-03 0,04611217 ! early endosome to late endosome transport GO:0045022 12 5 0,000 5,136E-03 0,04594075 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,136E-03 0,0457706 ! depyrimidination GO:0045008 10 5 0,000 5,136E-03 0,0456017 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,136E-03 0,04543405 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,136E-03 0,04526762 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,136E-03 0,04510241 ! zinc ion homeostasis GO:0055069 8 5 0,000 5,136E-03 0,0449384 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 5,136E-03 0,04477558 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 5,136E-03 0,04461394 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,136E-03 0,04445346 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,136E-03 0,04429413 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,136E-03 0,04413593 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 5,136E-03 0,04397887 ! peptidyl-arginine modification GO:0018195 9 5 0,000 5,136E-03 0,04382291 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,136E-03 0,04366806 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,136E-03 0,0435143 ! response to arsenic GO:0046685 10 5 0,000 5,136E-03 0,04336162 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,136E-03 0,04321 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,136E-03 0,04305945 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 5,136E-03 0,04290993 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 5,136E-03 0,04276146 ! response to cadmium ion GO:0046686 7 5 0,000 5,136E-03 0,042614 ! bile acid biosynthetic process GO:0006699 6 5 0,000 5,136E-03 0,04246756 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 5,136E-03 0,04232213 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,136E-03 0,04217768 ! decidualization GO:0046697 11 5 0,000 5,136E-03 0,04203422 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 5,136E-03 0,04189173 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 5,136E-03 0,04175021 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,136E-03 0,04160963 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,136E-03 0,04147 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 5,136E-03 0,04133131 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,136E-03 0,04119354 ! neural tube patterning GO:0021532 7 5 0,000 5,136E-03 0,04105668 ! embryonic cleavage GO:0040016 6 5 0,000 5,136E-03 0,04092073 ! peroxisome fission GO:0016559 5 5 0,000 5,136E-03 0,04078568 ! histone demethylation GO:0016577 10 5 0,000 5,136E-03 0,04065152 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 5,136E-03 0,04051823 ! mitotic recombination GO:0006312 9 5 0,000 5,136E-03 0,04038582 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,136E-03 0,04025427 ! metaphase plate congression GO:0051310 7 5 0,000 5,136E-03 0,04012358 ! regulation of sterol transport GO:0032371 7 5 0,000 5,136E-03 0,03999373 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,136E-03 0,03986471 ! enteric nervous system development GO:0048484 8 5 0,000 5,136E-03 0,03973653 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 5,136E-03 0,03960917 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 5,136E-03 0,03948262 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 5,136E-03 0,03935688 ! muscle cell proliferation GO:0033002 11 5 0,000 5,136E-03 0,03923194 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,136E-03 0,03910779 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 5,136E-03 0,03898442 ! plasminogen activation GO:0031639 5 5 0,000 5,136E-03 0,03886183 ! B cell homeostasis GO:0001782 13 5 0,000 5,136E-03 0,03874 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,136E-03 0,03861894 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,136E-03 0,03849863 ! metaphase GO:0051323 8 5 0,000 5,136E-03 0,03837907 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 5,136E-03 0,03826025 ! cellular response to nutrient GO:0031670 8 5 0,000 5,136E-03 0,03814216 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,136E-03 0,0380248 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,136E-03 0,03790816 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,136E-03 0,03779224 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 5,136E-03 0,03767702 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 5,136E-03 0,0375625 ! response to redox state GO:0051775 5 5 0,000 5,136E-03 0,03744867 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 5,136E-03 0,03733553 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 5,136E-03 0,03722308 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,136E-03 0,03711129 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,136E-03 0,03700018 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 5,136E-03 0,03688973 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,136E-03 0,03677994 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 5,136E-03 0,0366708 ! striatum development GO:0021756 9 5 0,000 5,136E-03 0,03656231 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 5,136E-03 0,03645446 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 5,136E-03 0,03634724 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,136E-03 0,03624065 ! glial cell migration GO:0008347 11 5 0,000 5,136E-03 0,03613468 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,136E-03 0,03602933 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 5,136E-03 0,0359246 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,136E-03 0,03582047 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,136E-03 0,03571694 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,136E-03 0,03561401 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,136E-03 0,03551167 ! neuroprotection GO:0043526 6 5 0,000 5,136E-03 0,03540992 ! neural plate development GO:0001840 8 5 0,000 5,136E-03 0,03530875 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,136E-03 0,03520815 ! regulation of sensory perception GO:0051931 7 5 0,000 5,136E-03 0,03510813 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,136E-03 0,03500867 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,136E-03 0,03490978 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 5,136E-03 0,03481144 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 5,136E-03 0,03471365 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,136E-03 0,03461642 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,136E-03 0,03451972 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,136E-03 0,03442357 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,136E-03 0,03432795 ! spindle assembly GO:0051225 6 5 0,000 5,136E-03 0,03423286 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,136E-03 0,03413829 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,136E-03 0,03404425 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,136E-03 0,03395072 ! drug metabolic process GO:0017144 6 5 0,000 5,136E-03 0,0338577 ! stem cell division GO:0017145 11 5 0,000 5,136E-03 0,03376519 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,136E-03 0,03367319 ! organ regeneration GO:0031100 7 5 0,000 5,136E-03 0,03358169 ! carnitine metabolic process GO:0009437 7 5 0,000 5,136E-03 0,03349068 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 5,136E-03 0,03340017 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,136E-03 0,03331014 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,161E-03 0,03984487 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,161E-03 0,03973805 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 6,161E-03 0,0396318 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,161E-03 0,03952611 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,161E-03 0,03942099 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 6,161E-03 0,03931642 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 6,161E-03 0,03921241 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,161E-03 0,03910895 ! sleep GO:0030431 13 6 0,000 6,161E-03 0,03900603 ! response to oxygen radical GO:0000305 11 6 0,000 6,161E-03 0,03890365 ! positive regulation of axon extension GO:0045773 11 6 0,000 6,161E-03 0,03880181 ! myoblast cell fate commitment GO:0048625 16 6 0,000 6,161E-03 0,0387005 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 6,161E-03 0,03859972 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 6,161E-03 0,03849946 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,161E-03 0,03839972 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,161E-03 0,03830049 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 6,161E-03 0,03820178 ! forebrain regionalization GO:0021871 8 6 0,000 6,161E-03 0,03810358 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,161E-03 0,03800588 ! male meiosis GO:0007140 7 6 0,000 6,161E-03 0,03790867 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,161E-03 0,03781197 ! response to zinc ion GO:0010043 9 6 0,000 6,161E-03 0,03771575 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,161E-03 0,03762003 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 6,161E-03 0,03752479 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 6,161E-03 0,03743003 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,161E-03 0,03733575 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,161E-03 0,03724194 ! malate metabolic process GO:0006108 11 6 0,000 6,161E-03 0,0371486 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 6,161E-03 0,03705573 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 6,161E-03 0,03696332 ! protein refolding GO:0042026 15 6 0,000 6,161E-03 0,03687137 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,161E-03 0,03677988 ! opsonization GO:0008228 8 6 0,000 6,161E-03 0,03668884 ! mating behavior GO:0007617 7 6 0,000 6,161E-03 0,03659825 ! neuron remodeling GO:0016322 15 6 0,000 6,161E-03 0,03650811 ! erythrocyte maturation GO:0043249 7 6 0,000 6,161E-03 0,03641841 ! embryonic hemopoiesis GO:0035162 14 6 0,000 6,161E-03 0,03632915 ! equilibrioception GO:0050957 14 6 0,000 6,161E-03 0,03624032 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,161E-03 0,03615193 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 6,161E-03 0,03606397 ! photoreceptor cell development GO:0042461 10 6 0,000 6,161E-03 0,03597644 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,161E-03 0,03588933 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,161E-03 0,03580264 ! response to interferon-gamma GO:0034341 15 6 0,000 6,161E-03 0,03571636 ! toxin metabolic process GO:0009404 11 6 0,000 6,161E-03 0,03563051 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,161E-03 0,03554506 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,161E-03 0,03546003 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 6,161E-03 0,0353754 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 6,161E-03 0,03529117 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 6,161E-03 0,03520734 ! cGMP-mediated signaling GO:0019934 13 6 0,000 6,161E-03 0,03512391 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,161E-03 0,03504088 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 6,161E-03 0,03495823 ! thymic T cell selection GO:0045061 12 6 0,000 6,161E-03 0,03487598 ! protein lipoylation GO:0009249 10 6 0,000 6,161E-03 0,03479411 ! cysteine metabolic process GO:0006534 10 6 0,000 6,161E-03 0,03471263 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,161E-03 0,03463152 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,161E-03 0,0345508 ! glutamate catabolic process GO:0006538 10 6 0,000 6,161E-03 0,03447045 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 6,161E-03 0,03439047 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,161E-03 0,03431086 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 6,161E-03 0,03423162 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 6,161E-03 0,03415275 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,161E-03 0,03407423 ! hyperosmotic response GO:0006972 9 6 0,000 6,161E-03 0,03399608 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 6,161E-03 0,03391829 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 6,161E-03 0,03384085 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,161E-03 0,03376376 ! urea metabolic process GO:0019627 7 6 0,000 6,161E-03 0,03368703 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,161E-03 0,03361064 ! neutrophil activation GO:0042119 8 6 0,000 6,161E-03 0,0335346 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,161E-03 0,0334589 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 6,161E-03 0,03338354 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,161E-03 0,03330852 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,161E-03 0,03323384 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,161E-03 0,03315949 ! neuron apoptosis GO:0051402 9 6 0,000 6,161E-03 0,03308547 ! nucleoside salvage GO:0043174 9 6 0,000 6,161E-03 0,03301178 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 6,161E-03 0,03293843 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,161E-03 0,03286539 ! T cell mediated immunity GO:0002456 16 6 0,000 6,161E-03 0,03279268 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,161E-03 0,03272029 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 6,161E-03 0,03264822 ! carnitine transport GO:0015879 10 6 0,000 6,161E-03 0,03257646 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 6,161E-03 0,03250502 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,161E-03 0,0324339 ! positive regulation of exocytosis GO:0045921 8 6 0,000 6,161E-03 0,03236308 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 6,161E-03 0,03229257 ! 5S class rRNA transcription GO:0042791 11 6 0,000 6,161E-03 0,03222237 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,161E-03 0,03215248 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 6,161E-03 0,03208288 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 6,161E-03 0,03201359 ! sodium ion homeostasis GO:0055078 11 6 0,000 6,161E-03 0,03194459 ! establishment of spindle localization GO:0051293 12 6 0,000 6,161E-03 0,0318759 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,161E-03 0,03180749 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,161E-03 0,03173938 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 6,161E-03 0,03167156 ! neural nucleus development GO:0048857 14 6 0,000 6,161E-03 0,03160403 ! response to UV-C GO:0010225 11 6 0,000 6,161E-03 0,03153679 ! astrocyte development GO:0014002 15 6 0,000 6,161E-03 0,03146983 ! protein targeting to lysosome GO:0006622 10 6 0,000 6,161E-03 0,03140316 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,161E-03 0,03133677 ! interaction with symbiont GO:0051702 13 6 0,000 6,161E-03 0,03127066 ! regulation of dendrite development GO:0050773 16 6 0,000 6,161E-03 0,03120482 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,161E-03 0,03113927 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 6,161E-03 0,03107399 ! response to copper ion GO:0046688 10 6 0,000 6,161E-03 0,03100898 ! response to exogenous dsRNA GO:0043330 10 6 0,000 6,161E-03 0,03094424 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 6,161E-03 0,03087977 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,161E-03 0,03081557 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,161E-03 0,03075164 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,161E-03 0,03068797 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 6,161E-03 0,03062457 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,161E-03 0,03056143 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,161E-03 0,03049854 ! hair follicle maturation GO:0048820 7 6 0,000 6,161E-03 0,03043592 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,161E-03 0,03037355 ! Schwann cell development GO:0014044 15 6 0,000 6,161E-03 0,03031143 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,161E-03 0,03024957 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,161E-03 0,03018797 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 6,161E-03 0,03012661 ! subpallium development GO:0021544 10 6 0,000 6,161E-03 0,0300655 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 6,161E-03 0,03000464 ! histone ubiquitination GO:0016574 8 6 0,000 6,161E-03 0,02994402 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 6,161E-03 0,02988365 ! maintenance of organ identity GO:0048496 9 6 0,000 6,161E-03 0,02982352 ! G2 phase GO:0051319 16 6 0,000 6,161E-03 0,02976364 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 6,161E-03 0,02970399 ! establishment of planar polarity GO:0001736 7 6 0,000 6,161E-03 0,02964458 ! regulation of mast cell activation GO:0033003 12 6 0,000 6,161E-03 0,02958541 ! membrane to membrane docking GO:0022614 14 6 0,000 6,161E-03 0,02952648 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,161E-03 0,02946778 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 6,161E-03 0,02940931 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,161E-03 0,02935107 ! receptor internalization GO:0031623 10 6 0,000 6,161E-03 0,02929307 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 6,161E-03 0,02923529 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 6,161E-03 0,02917774 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,161E-03 0,02912042 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 6,161E-03 0,02906332 ! protein deubiquitination GO:0016579 14 6 0,000 6,161E-03 0,02900644 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 6,161E-03 0,02894979 ! protein destabilization GO:0031648 9 6 0,000 6,161E-03 0,02889336 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,161E-03 0,02883714 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 6,161E-03 0,02878115 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,161E-03 0,02872537 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 6,161E-03 0,02866981 ! progesterone metabolic process GO:0042448 10 6 0,000 6,161E-03 0,02861446 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 6,161E-03 0,02855933 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 6,161E-03 0,02850441 ! negative regulation of axon extension GO:0030517 21 6 0,000 6,161E-03 0,0284497 ! removal of superoxide radicals GO:0019430 11 6 0,000 6,161E-03 0,02839519 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,161E-03 0,0283409 ! determination of adult lifespan GO:0008340 15 6 0,000 6,161E-03 0,02828682 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 6,161E-03 0,02823294 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 6,161E-03 0,02817926 ! cerebellar cortex formation GO:0021697 8 6 0,000 6,161E-03 0,02812579 ! catecholamine transport GO:0051937 9 6 0,000 6,161E-03 0,02807252 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 6,161E-03 0,02801945 ! sensory cilium assembly GO:0035058 10 6 0,000 6,161E-03 0,02796659 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,161E-03 0,02791392 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 6,161E-03 0,02786145 ! maternal placenta development GO:0001893 12 6 0,000 6,161E-03 0,02780918 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 6,161E-03 0,0277571 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,161E-03 0,02770522 ! negative regulation of B cell activation GO:0050869 13 6 0,000 6,161E-03 0,02765353 ! protein amino acid prenylation GO:0018346 16 6 0,000 6,161E-03 0,02760203 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,161E-03 0,02755073 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 6,161E-03 0,02749961 ! positive regulation of coagulation GO:0050820 12 6 0,000 6,161E-03 0,02744869 ! tRNA transcription GO:0009304 14 7 0,000 7,184E-03 0,03194837 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 7,184E-03 0,03188942 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 7,184E-03 0,03183069 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,184E-03 0,03177218 ! regulation of helicase activity GO:0051095 15 7 0,000 7,184E-03 0,03171388 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,184E-03 0,0316558 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 7,184E-03 0,03159793 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,184E-03 0,03154027 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 7,184E-03 0,03148282 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,184E-03 0,03142558 ! prostate gland development GO:0030850 13 7 0,000 7,184E-03 0,03136854 ! nucleotide-sugar transport GO:0015780 12 7 0,000 7,184E-03 0,03131171 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,184E-03 0,03125509 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,184E-03 0,03119868 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 7,184E-03 0,03114246 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,184E-03 0,03108645 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 7,184E-03 0,03103064 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 7,184E-03 0,03097503 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 7,184E-03 0,03091962 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 7,184E-03 0,0308644 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,184E-03 0,03080939 ! SMAD protein complex assembly GO:0007183 12 7 0,000 7,184E-03 0,03075457 ! glycolipid transport GO:0046836 10 7 0,000 7,184E-03 0,03069994 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,184E-03 0,03064551 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,184E-03 0,03059127 ! neuron adhesion GO:0007158 12 7 0,000 7,184E-03 0,03053722 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 7,184E-03 0,03048336 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,184E-03 0,03042969 ! actin-myosin filament sliding GO:0033275 11 7 0,000 7,184E-03 0,03037622 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 7,184E-03 0,03032292 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 7,184E-03 0,03026982 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 7,184E-03 0,0302169 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 7,184E-03 0,03016416 ! mRNA stabilization GO:0048255 18 7 0,000 7,184E-03 0,03011161 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 7,184E-03 0,03005925 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 7,184E-03 0,03000706 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 7,184E-03 0,02995505 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,184E-03 0,02990323 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,184E-03 0,02985158 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,184E-03 0,02980011 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,184E-03 0,02974882 ! lipoprotein transport GO:0042953 14 7 0,000 7,184E-03 0,02969771 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,184E-03 0,02964677 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,184E-03 0,029596 ! rhythmic behavior GO:0007622 15 7 0,000 7,184E-03 0,02954541 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 7,184E-03 0,02949499 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 7,184E-03 0,02944475 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 7,184E-03 0,02939467 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,184E-03 0,02934476 ! regulation of odontogenesis GO:0042481 13 7 0,000 7,184E-03 0,02929503 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,184E-03 0,02924546 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 7,184E-03 0,02919606 ! mechanosensory behavior GO:0007638 14 7 0,000 7,184E-03 0,02914682 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 7,184E-03 0,02909775 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,184E-03 0,02904885 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 7,184E-03 0,02900011 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,184E-03 0,02895154 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,184E-03 0,02890312 ! spinal cord patterning GO:0021511 13 7 0,000 7,184E-03 0,02885487 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 7,184E-03 0,02880678 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,184E-03 0,02875885 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 7,184E-03 0,02871107 ! adrenal gland development GO:0030325 17 7 0,000 7,184E-03 0,02866346 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 7,184E-03 0,028616 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 7,184E-03 0,0285687 ! ovulation GO:0030728 9 7 0,000 7,184E-03 0,02852156 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 7,184E-03 0,02847457 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,184E-03 0,02842774 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 7,184E-03 0,02838106 ! microtubule nucleation GO:0007020 20 7 0,000 7,184E-03 0,02833454 ! proline biosynthetic process GO:0006561 10 7 0,000 7,184E-03 0,02828816 ! thyroid hormone generation GO:0006590 13 7 0,000 7,184E-03 0,02824194 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 7,184E-03 0,02819587 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 7,184E-03 0,02814995 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 7,184E-03 0,02810417 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,184E-03 0,02805855 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,184E-03 0,02801307 ! galactose metabolic process GO:0006012 13 7 0,000 7,184E-03 0,02796775 ! vesicle fusion GO:0006906 17 7 0,000 7,184E-03 0,02792256 ! response to dietary excess GO:0002021 8 7 0,000 7,184E-03 0,02787753 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,184E-03 0,02783264 ! intracellular pH reduction GO:0051452 11 7 0,000 7,184E-03 0,02778789 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,184E-03 0,02774328 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 7,184E-03 0,02769882 ! organ growth GO:0035265 15 7 0,000 7,184E-03 0,02765451 ! purine salvage GO:0043101 10 7 0,000 7,184E-03 0,02761033 ! nucleoside transport GO:0015858 8 7 0,000 7,184E-03 0,02756629 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 7,184E-03 0,0275224 ! parturition GO:0007567 14 7 0,000 7,184E-03 0,02747864 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 7,184E-03 0,02743503 ! rRNA modification GO:0000154 14 7 0,000 7,184E-03 0,02739155 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 7,184E-03 0,02734821 ! spindle checkpoint GO:0031577 15 7 0,000 7,184E-03 0,027305 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 7,184E-03 0,02726193 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 7,184E-03 0,027219 ! macrophage differentiation GO:0030225 11 7 0,000 7,184E-03 0,02717621 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,184E-03 0,02713354 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,184E-03 0,02709101 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 7,184E-03 0,02704862 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,184E-03 0,02700635 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 7,184E-03 0,02696422 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,184E-03 0,02692222 ! fibrinolysis GO:0042730 10 7 0,000 7,184E-03 0,02688035 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 7,184E-03 0,02683861 ! eating behavior GO:0042755 7 7 0,000 7,184E-03 0,026797 ! B cell lineage commitment GO:0002326 21 7 0,000 7,184E-03 0,02675552 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,184E-03 0,02671417 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 7,184E-03 0,02667294 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 7,184E-03 0,02663184 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,184E-03 0,02659087 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 7,184E-03 0,02655003 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,184E-03 0,0265093 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 7,184E-03 0,02646871 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 7,184E-03 0,02642824 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 7,184E-03 0,02638789 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 7,184E-03 0,02634766 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,184E-03 0,02630756 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 7,184E-03 0,02626758 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,184E-03 0,02622772 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,184E-03 0,02618798 ! regulation of meiosis GO:0040020 12 7 0,000 7,184E-03 0,02614836 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 7,184E-03 0,02610886 ! T cell lineage commitment GO:0002360 16 7 0,000 7,184E-03 0,02606948 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 7,184E-03 0,02603022 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,184E-03 0,02599108 ! oxygen homeostasis GO:0032364 12 7 0,000 7,184E-03 0,02595205 ! transcription termination GO:0006353 13 7 0,000 7,184E-03 0,02591314 ! response to tumor cell GO:0002347 13 7 0,000 7,184E-03 0,02587435 ! regulation of respiratory burst GO:0060263 11 7 0,000 7,184E-03 0,02583567 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,184E-03 0,02579711 ! anaphase GO:0051322 17 7 0,000 7,184E-03 0,02575867 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 7,184E-03 0,02572034 ! axonal fasciculation GO:0007413 18 7 0,000 7,184E-03 0,02568212 ! negative regulation of nuclear division GO:0051784 14 7 0,000 7,184E-03 0,02564402 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 7,184E-03 0,02560602 ! peptidyl-threonine modification GO:0018210 25 7 0,000 7,184E-03 0,02556815 ! diuresis GO:0030146 12 7 0,000 7,184E-03 0,02553038 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,184E-03 0,02549272 ! thiamin metabolic process GO:0006772 7 7 0,000 7,184E-03 0,02545518 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,184E-03 0,02541774 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 7,184E-03 0,02538042 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 7,184E-03 0,02534321 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,184E-03 0,0253061 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,184E-03 0,0252691 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,184E-03 0,02523221 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,184E-03 0,02519543 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 7,184E-03 0,02515876 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,184E-03 0,02512219 ! glycolipid catabolic process GO:0019377 15 7 0,000 7,184E-03 0,02508573 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,184E-03 0,02504937 ! lymph node development GO:0048535 10 7 0,000 7,184E-03 0,02501312 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 7,184E-03 0,02497697 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,184E-03 0,02494093 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 7,184E-03 0,02490499 ! endosome to lysosome transport GO:0008333 11 7 0,000 7,184E-03 0,02486916 ! protein modification by small protein removal GO:0070646 16 7 0,000 7,184E-03 0,02483343 ! adult feeding behavior GO:0008343 9 7 0,000 7,184E-03 0,0247978 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 7,184E-03 0,02476227 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,184E-03 0,02472685 ! muscle adaptation GO:0043500 14 7 0,000 7,184E-03 0,02469152 ! embryonic heart tube development GO:0035050 10 7 0,000 7,184E-03 0,0246563 ! retina homeostasis GO:0001895 12 7 0,000 7,184E-03 0,02462118 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,184E-03 0,02458615 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 7,184E-03 0,02455123 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 7,184E-03 0,02451641 ! protein prenylation GO:0018342 18 7 0,000 7,184E-03 0,02448168 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 7,184E-03 0,02444705 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,184E-03 0,02441252 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 8,206E-03 0,02784681 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 8,206E-03 0,02780759 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 8,206E-03 0,02776848 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 8,206E-03 0,02772948 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 8,206E-03 0,02769059 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,206E-03 0,0276518 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,206E-03 0,02761313 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 8,206E-03 0,02757457 ! neutral lipid catabolic process GO:0046461 13 8 0,000 8,206E-03 0,02753611 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 8,206E-03 0,02749776 ! meiotic prophase I GO:0007128 13 8 0,000 8,206E-03 0,02745951 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,206E-03 0,02742137 ! oligopeptide transport GO:0006857 15 8 0,000 8,206E-03 0,02738334 ! UTP metabolic process GO:0046051 8 8 0,000 8,206E-03 0,02734541 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 8,206E-03 0,02730759 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 8,206E-03 0,02726987 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 8,206E-03 0,02723226 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,206E-03 0,02719475 ! succinate metabolic process GO:0006105 14 8 0,000 8,206E-03 0,02715734 ! membrane hyperpolarization GO:0060081 10 8 0,000 8,206E-03 0,02712004 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,206E-03 0,02708284 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 8,206E-03 0,02704574 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,206E-03 0,02700874 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 8,206E-03 0,02697184 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,206E-03 0,02693505 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,206E-03 0,02689835 ! ganglioside metabolic process GO:0001573 19 8 0,000 8,206E-03 0,02686175 ! reflex GO:0060004 16 8 0,000 8,206E-03 0,02682526 ! negative regulation of endocytosis GO:0045806 11 8 0,000 8,206E-03 0,02678886 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 8,206E-03 0,02675256 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,206E-03 0,02671636 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 8,206E-03 0,02668026 ! glycerolipid catabolic process GO:0046503 13 8 0,000 8,206E-03 0,02664425 ! hemoglobin metabolic process GO:0020027 13 8 0,000 8,206E-03 0,02660834 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,206E-03 0,02657253 ! pigment granule organization GO:0048753 16 8 0,000 8,206E-03 0,02653681 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,206E-03 0,02650119 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 8,206E-03 0,02646567 ! astrocyte differentiation GO:0048708 18 8 0,000 8,206E-03 0,02643024 ! histidine metabolic process GO:0006547 16 8 0,000 8,206E-03 0,0263949 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,206E-03 0,02635966 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 8,206E-03 0,02632452 ! glycine catabolic process GO:0006546 13 8 0,000 8,206E-03 0,02628947 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 8,206E-03 0,02625451 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 8,206E-03 0,02621964 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 8,206E-03 0,02618487 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 8,206E-03 0,02615018 ! regulation of pigmentation during development GO:0048070 24 8 0,000 8,206E-03 0,02611559 ! melanin metabolic process GO:0006582 15 8 0,000 8,206E-03 0,02608109 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 8,206E-03 0,02604669 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 8,206E-03 0,02601237 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,206E-03 0,02597814 ! macrophage activation GO:0042116 12 8 0,000 8,206E-03 0,02594401 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,206E-03 0,02590996 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,206E-03 0,025876 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 8,206E-03 0,02584213 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,206E-03 0,02580835 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,206E-03 0,02577466 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 8,206E-03 0,02574105 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,206E-03 0,02570754 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 8,206E-03 0,02567411 ! osteoblast development GO:0002076 16 8 0,000 8,206E-03 0,02564076 ! positive regulation of vasodilation GO:0045909 13 8 0,000 8,206E-03 0,02560751 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,206E-03 0,02557434 ! negative regulation of translational initiation GO:0045947 10 8 0,000 8,206E-03 0,02554125 ! Schwann cell differentiation GO:0014037 19 8 0,000 8,206E-03 0,02550825 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 8,206E-03 0,02547534 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,206E-03 0,02544251 ! response to UV-B GO:0010224 16 8 0,000 8,206E-03 0,02540977 ! protein targeting to vacuole GO:0006623 12 8 0,000 8,206E-03 0,02537711 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,206E-03 0,02534453 ! intermediate filament organization GO:0045109 12 8 0,000 8,206E-03 0,02531204 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 8,206E-03 0,02527963 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 8,206E-03 0,0252473 ! cellular extravasation GO:0045123 12 8 0,000 8,206E-03 0,02521506 ! cardiac muscle cell development GO:0055013 13 8 0,000 8,206E-03 0,02518289 ! regulation of circadian rhythm GO:0042752 16 8 0,000 8,206E-03 0,02515081 ! response to antibiotic GO:0046677 11 8 0,000 8,206E-03 0,02511882 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 8,206E-03 0,0250869 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 8,206E-03 0,02505506 ! DNA topological change GO:0006265 12 8 0,000 8,206E-03 0,02502331 ! response to tropane GO:0014073 15 8 0,000 8,206E-03 0,02499163 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 8,206E-03 0,02496004 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 8,206E-03 0,02492852 ! melanosome transport GO:0032402 13 8 0,000 8,206E-03 0,02489709 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 8,206E-03 0,02486573 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 8,206E-03 0,02483445 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,206E-03 0,02480325 ! mast cell activation GO:0045576 14 8 0,000 8,206E-03 0,02477213 ! multicellular organismal aging GO:0010259 18 8 0,000 8,206E-03 0,02474109 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 8,206E-03 0,02471012 ! dendrite morphogenesis GO:0048813 13 8 0,000 8,206E-03 0,02467924 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 8,206E-03 0,02464843 ! nucleosome disassembly GO:0006337 14 8 0,000 8,206E-03 0,02461769 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,206E-03 0,02458703 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 8,206E-03 0,02455645 ! leukocyte activation during immune response GO:0002366 13 8 0,000 8,206E-03 0,02452595 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,206E-03 0,02449552 ! establishment of chromosome localization GO:0051303 12 8 0,000 8,206E-03 0,02446517 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 8,206E-03 0,02443489 ! intracellular lipid transport GO:0032365 13 8 0,000 8,206E-03 0,02440468 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,206E-03 0,02437455 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 8,206E-03 0,0243445 ! regulation of macrophage activation GO:0043030 15 8 0,000 8,206E-03 0,02431452 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 8,206E-03 0,02428461 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,206E-03 0,02425478 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 8,206E-03 0,02422502 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 8,206E-03 0,02419533 ! hormone catabolic process GO:0042447 17 8 0,000 8,206E-03 0,02416571 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,206E-03 0,02413617 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 8,206E-03 0,0241067 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 8,206E-03 0,0240773 ! ATP catabolic process GO:0006200 11 8 0,000 8,206E-03 0,02404798 ! blastocyst growth GO:0001832 19 8 0,000 8,206E-03 0,02401872 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,206E-03 0,02398954 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,206E-03 0,02396042 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 8,206E-03 0,02393138 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,206E-03 0,02390241 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 8,206E-03 0,02387351 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 8,206E-03 0,02384467 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 8,206E-03 0,02381591 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 8,206E-03 0,02378722 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 8,206E-03 0,02375859 ! amino sugar catabolic process GO:0046348 10 8 0,000 8,206E-03 0,02373003 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 8,206E-03 0,02370155 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,206E-03 0,02367313 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,206E-03 0,02364478 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,206E-03 0,02361649 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,206E-03 0,02358828 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,206E-03 0,02356013 ! NAD biosynthetic process GO:0009435 13 8 0,000 8,206E-03 0,02353205 ! regulation of developmental growth GO:0048638 15 9 0,000 9,227E-03 0,02642888 ! axon extension GO:0048675 15 9 0,000 9,227E-03 0,02639746 ! autophagic vacuole formation GO:0000045 15 9 0,000 9,227E-03 0,02636611 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,227E-03 0,02633483 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 9,227E-03 0,02630363 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 9,227E-03 0,0262725 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,227E-03 0,02624144 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 9,227E-03 0,02621046 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 9,227E-03 0,02617955 ! cell proliferation in forebrain GO:0021846 15 9 0,000 9,227E-03 0,02614872 ! phosphate transport GO:0006817 19 9 0,000 9,227E-03 0,02611795 ! reproductive behavior GO:0019098 19 9 0,000 9,227E-03 0,02608726 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,227E-03 0,02605664 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 9,227E-03 0,0260261 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 9,227E-03 0,02599562 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 9,227E-03 0,02596522 ! GTP metabolic process GO:0046039 9 9 0,000 9,227E-03 0,02593488 ! RNA methylation GO:0001510 15 9 0,000 9,227E-03 0,02590462 ! elastic fiber assembly GO:0048251 15 9 0,000 9,227E-03 0,02587443 ! induction of positive chemotaxis GO:0050930 15 9 0,000 9,227E-03 0,02584431 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 9,227E-03 0,02581426 ! artery development GO:0060840 24 9 0,000 9,227E-03 0,02578427 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 9,227E-03 0,02575436 ! regulation of glycolysis GO:0006110 21 9 0,000 9,227E-03 0,02572452 ! cerebral cortex cell migration GO:0021795 15 9 0,000 9,227E-03 0,02569475 ! keratinocyte proliferation GO:0043616 14 9 0,000 9,227E-03 0,02566504 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 9,227E-03 0,0256354 ! chemosensory behavior GO:0007635 20 9 0,000 9,227E-03 0,02560584 ! microtubule bundle formation GO:0001578 21 9 0,000 9,227E-03 0,02557634 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,227E-03 0,02554691 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 9,227E-03 0,02551754 ! leukocyte degranulation GO:0043299 16 9 0,000 9,227E-03 0,02548824 ! bile acid and bile salt transport GO:0015721 13 9 0,000 9,227E-03 0,02545901 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 9,227E-03 0,02542985 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 9,227E-03 0,02540076 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,227E-03 0,02537173 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,227E-03 0,02534276 ! protein targeting to ER GO:0045047 22 9 0,000 9,227E-03 0,02531387 ! ceramide biosynthetic process GO:0046513 19 9 0,000 9,227E-03 0,02528503 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 9,227E-03 0,02525627 ! T cell selection GO:0045058 23 9 0,000 9,227E-03 0,02522757 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 9,227E-03 0,02519893 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 9,227E-03 0,02517036 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,227E-03 0,02514186 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 9,227E-03 0,02511342 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 9,227E-03 0,02508504 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 9,227E-03 0,02505673 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,227E-03 0,02502848 ! mannose metabolic process GO:0006013 13 9 0,000 9,227E-03 0,02500029 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 9,227E-03 0,02497217 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 9,227E-03 0,02494411 ! Rac protein signal transduction GO:0016601 17 9 0,000 9,227E-03 0,02491612 ! receptor clustering GO:0043113 18 9 0,000 9,227E-03 0,02488818 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 9,227E-03 0,02486031 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,227E-03 0,02483251 ! ruffle organization GO:0031529 15 9 0,000 9,227E-03 0,02480476 ! retinol metabolic process GO:0042572 18 9 0,000 9,227E-03 0,02477708 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 9,227E-03 0,02474945 ! behavioral fear response GO:0001662 22 9 0,000 9,227E-03 0,02472189 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 9,227E-03 0,02469439 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 9,227E-03 0,02466696 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 9,227E-03 0,02463958 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 9,227E-03 0,02461226 ! protein heterooligomerization GO:0051291 16 9 0,000 9,227E-03 0,02458501 ! oligodendrocyte development GO:0014003 10 9 0,000 9,227E-03 0,02455781 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 9,227E-03 0,02453067 ! segment specification GO:0007379 13 9 0,000 9,227E-03 0,0245036 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,227E-03 0,02447658 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 9,227E-03 0,02444963 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,227E-03 0,02442273 ! response to amine stimulus GO:0014075 13 9 0,000 9,227E-03 0,02439589 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,227E-03 0,02436911 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 9,227E-03 0,02434239 ! erythrocyte development GO:0048821 15 9 0,000 9,227E-03 0,02431573 ! gas homeostasis GO:0033483 16 9 0,000 9,227E-03 0,02428913 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,227E-03 0,02426258 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 9,227E-03 0,02423609 ! renal water homeostasis GO:0003091 14 9 0,000 9,227E-03 0,02420966 ! postreplication repair GO:0006301 22 9 0,000 9,227E-03 0,02418329 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 9,227E-03 0,02415698 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 9,227E-03 0,02413072 ! icosanoid secretion GO:0032309 15 9 0,000 9,227E-03 0,02410452 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,227E-03 0,02407837 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 9,227E-03 0,02405229 ! regulation of cell division GO:0051302 15 9 0,000 9,227E-03 0,02402626 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 9,227E-03 0,02400028 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 9,227E-03 0,02397436 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,227E-03 0,0239485 ! sterol catabolic process GO:0016127 11 9 0,000 9,227E-03 0,02392269 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,227E-03 0,02389694 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 9,227E-03 0,02387125 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 9,227E-03 0,02384561 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 9,227E-03 0,02382002 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 9,227E-03 0,02379449 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 9,227E-03 0,02376902 ! musculoskeletal movement GO:0050881 14 9 0,000 9,227E-03 0,02374359 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 9,227E-03 0,02371823 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 9,227E-03 0,02369291 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,227E-03 0,02366766 ! purine base metabolic process GO:0006144 21 9 0,000 9,227E-03 0,02364245 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 9,227E-03 0,0236173 ! pigment granule transport GO:0051904 17 9 0,000 9,227E-03 0,0235922 ! regulation of fibrinolysis GO:0051917 16 9 0,000 9,227E-03 0,02356716 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 9,227E-03 0,02354216 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,227E-03 0,02351723 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,227E-03 0,02349234 ! mitochondrion localization GO:0051646 15 9 0,000 9,227E-03 0,02346751 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01024717 0,02603451 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01024717 0,02600705 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01024717 0,02597965 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01024717 0,0259523 ! synapsis GO:0007129 13 10 0,000 0,01024717 0,02592501 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01024717 0,02589778 ! N-glycan processing GO:0006491 20 10 0,000 0,01024717 0,0258706 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01024717 0,02584348 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01024717 0,02581642 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01024717 0,02578942 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01024717 0,02576247 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01024717 0,02573558 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01024717 0,02570874 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01024717 0,02568196 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01024717 0,02565524 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01024717 0,02562857 ! androgen metabolic process GO:0008209 17 10 0,000 0,01024717 0,02560196 ! phospholipid efflux GO:0033700 16 10 0,000 0,01024717 0,0255754 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01024717 0,0255489 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01024717 0,02552245 ! lung alveolus development GO:0048286 26 10 0,000 0,01024717 0,02549605 ! pathogenesis GO:0009405 13 10 0,000 0,01024717 0,02546972 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01024717 0,02544343 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01024717 0,0254172 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01024717 0,02539102 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01024717 0,0253649 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01024717 0,02533883 ! endoderm development GO:0007492 16 10 0,000 0,01024717 0,02531282 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01024717 0,02528686 ! arginine catabolic process GO:0006527 13 10 0,000 0,01024717 0,02526095 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01024717 0,02523509 ! proline metabolic process GO:0006560 13 10 0,000 0,01024717 0,02520929 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01024717 0,02518354 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01024717 0,02515784 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01024717 0,0251322 ! V(D)J recombination GO:0033151 28 10 0,000 0,01024717 0,0251066 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01024717 0,02508106 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01024717 0,02505557 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01024717 0,02503014 ! B cell proliferation GO:0042100 18 10 0,000 0,01024717 0,02500475 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01024717 0,02497942 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01024717 0,02495413 ! multicellular organism growth GO:0035264 18 10 0,000 0,01024717 0,0249289 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01024717 0,02490372 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01024717 0,02487859 ! epithelial cell development GO:0002064 20 10 0,000 0,01024717 0,02485351 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01024717 0,02482848 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01024717 0,02480351 ! macroautophagy GO:0016236 17 10 0,000 0,01024717 0,02477858 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01024717 0,0247537 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01024717 0,02472887 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01024717 0,02470409 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01024717 0,02467936 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01024717 0,02465468 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01024717 0,02463005 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01024717 0,02460547 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01024717 0,02458094 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01024717 0,02455646 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01024717 0,02453202 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01024717 0,02450764 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01024717 0,0244833 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01024717 0,02445901 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01024717 0,02443477 ! response to dsRNA GO:0043331 20 10 0,000 0,01024717 0,02441058 ! DNA ligation GO:0006266 19 10 0,000 0,01024717 0,02438643 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01024717 0,02436234 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01024717 0,02433829 ! melanosome localization GO:0032400 16 10 0,000 0,01024717 0,02431428 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01024717 0,02429033 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01024717 0,02426642 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01024717 0,02424256 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01024717 0,02421875 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01024717 0,02419498 ! mRNA cleavage GO:0006379 17 10 0,000 0,01024717 0,02417126 ! protein sumoylation GO:0016925 15 10 0,000 0,01024717 0,02414759 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01024717 0,02412396 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01024717 0,02410038 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01024717 0,02407684 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01024717 0,02405335 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01024717 0,02402991 ! salivary gland development GO:0007431 27 10 0,000 0,01024717 0,02400651 ! prophase GO:0051324 15 10 0,000 0,01024717 0,02398316 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01024717 0,02395985 ! apical protein localization GO:0045176 15 10 0,000 0,01024717 0,02393659 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01024717 0,02391337 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01024717 0,0238902 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01024717 0,02386707 ! midbrain development GO:0030901 13 10 0,000 0,01024717 0,02384399 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01024717 0,02382095 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01024717 0,02379796 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01024717 0,02377501 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01024717 0,0237521 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01024717 0,02372924 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01024717 0,02370643 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01024717 0,02368365 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01024717 0,02366093 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01024717 0,02363824 ! oocyte development GO:0048599 17 10 0,000 0,01024717 0,0236156 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01024717 0,023593 ! blastocyst formation GO:0001825 17 10 0,000 0,01024717 0,02357044 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01024717 0,02354793 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01024717 0,02352546 ! activation of innate immune response GO:0002218 12 10 0,000 0,01024717 0,02350304 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01024717 0,02348065 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01024717 0,02345831 ! response to nicotine GO:0035094 20 10 0,000 0,01024717 0,02343601 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01024717 0,02341376 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01024717 0,02339154 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01024717 0,02336937 ! localization within membrane GO:0051668 20 10 0,000 0,01024717 0,02334724 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01126628 0,0256449 ! respiratory burst GO:0045730 17 11 0,000 0,01126628 0,02562066 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01126628 0,02559647 ! neuron fate specification GO:0048665 17 11 0,000 0,01126628 0,02557232 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01126628 0,02554822 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01126628 0,02552416 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01126628 0,02550015 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01126628 0,02547619 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01126628 0,02545227 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01126628 0,02542839 ! response to pain GO:0048265 24 11 0,000 0,01126628 0,02540456 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01126628 0,02538077 ! T cell proliferation GO:0042098 26 11 0,000 0,01126628 0,02535703 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01126628 0,02533333 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01126628 0,02530968 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01126628 0,02528607 ! bone resorption GO:0045453 16 11 0,000 0,01126628 0,0252625 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01126628 0,02523898 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01126628 0,0252155 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01126628 0,02519207 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01126628 0,02516867 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01126628 0,02514533 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01126628 0,02512202 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01126628 0,02509876 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01126628 0,02507554 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01126628 0,02505237 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01126628 0,02502924 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01126628 0,02500615 ! lipid digestion GO:0044241 18 11 0,000 0,01126628 0,0249831 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01126628 0,02496009 ! UV protection GO:0009650 19 11 0,000 0,01126628 0,02493713 ! adult heart development GO:0007512 14 11 0,000 0,01126628 0,02491421 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01126628 0,02489133 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01126628 0,0248685 ! temperature homeostasis GO:0001659 17 11 0,000 0,01126628 0,0248457 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01126628 0,02482295 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01126628 0,02480024 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01126628 0,02477757 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01126628 0,02475494 ! regulation of organ growth GO:0046620 13 11 0,000 0,01126628 0,02473236 ! pigment granule localization GO:0051875 20 11 0,000 0,01126628 0,02470981 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01126628 0,02468731 ! vasoconstriction GO:0042310 18 11 0,000 0,01126628 0,02466484 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01126628 0,02464242 ! embryonic axis specification GO:0000578 18 11 0,000 0,01126628 0,02462004 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01126628 0,0245977 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01126628 0,0245754 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01126628 0,02455314 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01126628 0,02453092 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01126628 0,02450874 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01126628 0,0244866 ! zymogen activation GO:0031638 15 11 0,000 0,01126628 0,0244645 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01126628 0,02444244 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01126628 0,02442042 ! nucleosome positioning GO:0016584 15 11 0,000 0,01126628 0,02439844 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01126628 0,0243765 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01126628 0,02435459 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01126628 0,02433273 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01126628 0,02431091 ! acid secretion GO:0046717 18 11 0,000 0,01126628 0,02428912 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01126628 0,02426738 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01126628 0,02424567 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01126628 0,02422401 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01126628 0,02420238 ! oocyte differentiation GO:0009994 18 11 0,000 0,01126628 0,02418079 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01126628 0,02415924 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,01126628 0,02413772 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01126628 0,02411625 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01126628 0,02409481 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01126628 0,02407341 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01126628 0,02405205 ! embryonic gut development GO:0048566 15 11 0,000 0,01126628 0,02403073 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01126628 0,02400944 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01126628 0,0239882 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01126628 0,02396699 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01126628 0,02394581 ! defense response to fungus GO:0050832 13 11 0,000 0,01126628 0,02392468 ! lysogeny GO:0030069 21 11 0,000 0,01126628 0,02390358 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01126628 0,02388252 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01126628 0,0238615 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01126628 0,02384051 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01126628 0,02381956 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01126628 0,02379865 ! nucleus localization GO:0051647 19 11 0,000 0,01126628 0,02377777 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01126628 0,02375693 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01228437 0,02588108 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01228437 0,02585844 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01228437 0,02583584 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01228437 0,02581327 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01228437 0,02579075 ! virus-host interaction GO:0019048 29 12 0,000 0,01228437 0,02576826 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01228437 0,02574582 ! cartilage condensation GO:0001502 20 12 0,000 0,01228437 0,02572341 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01228437 0,02570104 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01228437 0,02567871 ! protein complex disassembly GO:0043241 27 12 0,000 0,01228437 0,02565642 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01228437 0,02563417 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01228437 0,02561196 ! hippocampus development GO:0021766 26 12 0,000 0,01228437 0,02558978 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01228437 0,02556764 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01228437 0,02554555 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01228437 0,02552349 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01228437 0,02550146 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01228437 0,02547948 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01228437 0,02545753 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01228437 0,02543563 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01228437 0,02541376 ! drug transport GO:0015893 16 12 0,000 0,01228437 0,02539192 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01228437 0,02537013 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01228437 0,02534837 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01228437 0,02532665 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01228437 0,02530496 ! focal adhesion formation GO:0048041 35 12 0,000 0,01228437 0,02528332 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01228437 0,02526171 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01228437 0,02524013 ! forebrain cell migration GO:0021885 21 12 0,000 0,01228437 0,0252186 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01228437 0,0251971 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01228437 0,02517564 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01228437 0,02515421 ! entry into host cell GO:0030260 32 12 0,000 0,01228437 0,02513282 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01228437 0,02511147 ! monoamine transport GO:0015844 18 12 0,000 0,01228437 0,02509015 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01228437 0,02506887 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01228437 0,02504762 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01228437 0,02502642 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01228437 0,02500524 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01228437 0,02498411 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01228437 0,024963 ! protein homotetramerization GO:0051289 21 12 0,000 0,01228437 0,02494194 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01228437 0,02492091 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01228437 0,02489991 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01228437 0,02487895 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01228437 0,02485803 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01228437 0,02483714 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01228437 0,02481629 ! cranial nerve development GO:0021545 20 12 0,000 0,01228437 0,02479547 ! fucose catabolic process GO:0019317 22 12 0,000 0,01228437 0,02477468 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01228437 0,02475393 ! histone acetylation GO:0016573 26 12 0,000 0,01228437 0,02473322 ! histone methylation GO:0016571 26 12 0,000 0,01228437 0,02471254 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01228437 0,02469189 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01228437 0,02467128 ! gland morphogenesis GO:0022612 29 12 0,000 0,01228437 0,02465071 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01228437 0,02463016 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01228437 0,02460966 ! T cell homeostasis GO:0043029 25 12 0,000 0,01228437 0,02458918 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01228437 0,02456874 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01228437 0,02454834 ! spleen development GO:0048536 22 12 0,000 0,01228437 0,02452796 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01228437 0,02450763 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01228437 0,02448732 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01228437 0,02446705 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01228437 0,02444681 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01228437 0,02442661 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01228437 0,02440644 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01228437 0,0243863 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01228437 0,0243662 ! response to cold GO:0009409 17 12 0,000 0,01228437 0,02434613 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01228437 0,02432609 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01228437 0,02430608 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01330145 0,02629687 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01330145 0,02627528 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01330145 0,02625373 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01330145 0,02623221 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01330145 0,02621072 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01330145 0,02618927 ! lipid localization GO:0010876 28 13 0,000 0,01330145 0,02616786 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01330145 0,02614648 ! organelle fusion GO:0048284 32 13 0,000 0,01330145 0,02612514 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01330145 0,02610383 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01330145 0,02608255 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01330145 0,02606131 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01330145 0,02604011 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01330145 0,02601894 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01330145 0,0259978 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01330145 0,0259767 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01330145 0,02595563 ! methionine metabolic process GO:0006555 27 13 0,000 0,01330145 0,0259346 ! plasma membrane organization GO:0007009 24 13 0,000 0,01330145 0,0259136 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01330145 0,02589263 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01330145 0,0258717 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01330145 0,0258508 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01330145 0,02582994 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01330145 0,02580911 ! response to X-ray GO:0010165 25 13 0,000 0,01330145 0,02578831 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01330145 0,02576755 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01330145 0,02574681 ! exocrine system development GO:0035272 32 13 0,000 0,01330145 0,02572612 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01330145 0,02570545 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01330145 0,02568482 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01330145 0,02566423 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01330145 0,02564366 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01330145 0,02562313 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01330145 0,02560263 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01330145 0,02558217 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01330145 0,02556173 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01330145 0,02554133 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01330145 0,02552097 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01330145 0,02550063 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01330145 0,02548033 ! ribosome assembly GO:0042255 17 13 0,000 0,01330145 0,02546006 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01330145 0,02543982 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01330145 0,02541961 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01330145 0,02539944 ! chromatin silencing GO:0006342 26 13 0,000 0,01330145 0,0253793 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01330145 0,02535918 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01330145 0,02533911 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01330145 0,02531906 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01330145 0,02529904 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01330145 0,02527906 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01330145 0,02525911 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01330145 0,02523919 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01330145 0,0252193 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01330145 0,02519944 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01330145 0,02517962 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01330145 0,02515982 ! embryonic placenta development GO:0001892 23 13 0,000 0,01330145 0,02514006 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01330145 0,02512032 ! insulin secretion GO:0030073 23 13 0,000 0,01330145 0,02510062 ! actin filament polymerization GO:0030041 24 13 0,000 0,01330145 0,02508095 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01330145 0,02506131 ! acrosome reaction GO:0007340 18 13 0,000 0,01330145 0,0250417 ! rRNA transcription GO:0009303 25 14 0,000 0,01431752 0,0269335 ! lactation GO:0007595 26 14 0,000 0,01431752 0,02691246 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01431752 0,02689145 ! reproductive cellular process GO:0048610 20 14 0,000 0,01431752 0,02687047 ! tRNA modification GO:0006400 20 14 0,000 0,01431752 0,02684953 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01431752 0,02682862 ! regulation of S phase GO:0033261 23 14 0,000 0,01431752 0,02680774 ! water transport GO:0006833 21 14 0,000 0,01431752 0,02678689 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01431752 0,02676608 ! non-recombinational repair GO:0000726 25 14 0,000 0,01431752 0,0267453 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01431752 0,02672455 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01431752 0,02670383 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01431752 0,02668315 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01431752 0,0266625 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01431752 0,02664188 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01431752 0,02662129 ! palate development GO:0060021 31 14 0,000 0,01431752 0,02660073 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01431752 0,02658021 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01431752 0,02655971 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01431752 0,02653925 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01431752 0,02651882 ! arginine metabolic process GO:0006525 17 14 0,000 0,01431752 0,02649842 ! regulation of heart rate GO:0002027 24 14 0,000 0,01431752 0,02647805 ! organic alcohol transport GO:0015850 29 14 0,000 0,01431752 0,02645772 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01431752 0,02643741 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01431752 0,02641714 ! embryo implantation GO:0007566 30 14 0,000 0,01431752 0,02639689 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01431752 0,02637668 ! L-amino acid transport GO:0015807 30 14 0,000 0,01431752 0,0263565 ! bone mineralization GO:0030282 17 14 0,000 0,01431752 0,02633635 ! stem cell development GO:0048864 43 14 0,000 0,01431752 0,02631623 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01431752 0,02629614 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01431752 0,02627608 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01431752 0,02625606 ! cerebellum development GO:0021549 21 14 0,000 0,01431752 0,02623606 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01431752 0,02621609 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01431752 0,02619616 ! response to gamma radiation GO:0010332 28 14 0,000 0,01431752 0,02617625 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01431752 0,02615638 ! cofactor transport GO:0051181 26 14 0,000 0,01431752 0,02613653 ! NADP metabolic process GO:0006739 24 14 0,000 0,01431752 0,02611671 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01431752 0,02609693 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01431752 0,02607717 ! intestinal absorption GO:0050892 25 14 0,000 0,01431752 0,02605745 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01431752 0,02603775 ! oxygen transport GO:0015671 21 14 0,000 0,01431752 0,02601809 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01431752 0,02599845 ! male genitalia development GO:0030539 24 14 0,000 0,01431752 0,02597884 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01431752 0,02595927 ! regulation of axon extension GO:0030516 37 14 0,000 0,01431752 0,02593972 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01431752 0,0259202 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01431752 0,02590071 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01533257 0,02771613 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01533257 0,02769532 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01533257 0,02767454 ! superoxide anion generation GO:0042554 20 15 0,000 0,01533257 0,0276538 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01533257 0,02763308 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01533257 0,0276124 ! copper ion transport GO:0006825 20 15 0,000 0,01533257 0,02759175 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01533257 0,02757112 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01533257 0,02755053 ! sulfate transport GO:0008272 23 15 0,000 0,01533257 0,02752997 ! response to cAMP GO:0051591 22 15 0,000 0,01533257 0,02750944 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01533257 0,02748895 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01533257 0,02746848 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01533257 0,02744804 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01533257 0,02742763 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01533257 0,02740725 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01533257 0,02738691 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01533257 0,02736659 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01533257 0,0273463 ! pituitary gland development GO:0021983 29 15 0,000 0,01533257 0,02732605 ! vesicle coating GO:0006901 33 15 0,000 0,01533257 0,02730582 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01533257 0,02728562 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01533257 0,02726546 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01533257 0,02724532 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01533257 0,02722521 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01533257 0,02720514 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01533257 0,02718509 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01533257 0,02716507 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01533257 0,02714508 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01533257 0,02712512 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01533257 0,02710519 ! histone deacetylation GO:0016575 20 15 0,000 0,01533257 0,02708529 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01533257 0,02706542 ! tissue regeneration GO:0042246 26 15 0,000 0,01533257 0,02704558 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01533257 0,02702576 ! water homeostasis GO:0030104 27 15 0,000 0,01533257 0,02700598 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01533257 0,02698622 ! muscle maintenance GO:0046716 26 15 0,000 0,01533257 0,02696649 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01533257 0,0269468 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01533257 0,02692713 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01533257 0,02690749 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01533257 0,02688788 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01533257 0,02686829 ! cell killing GO:0001906 29 15 0,000 0,01533257 0,02684874 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01533257 0,02682921 ! detection of bacterium GO:0016045 18 15 0,000 0,01533257 0,02680971 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01533257 0,02679024 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01533257 0,0267708 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01533257 0,02675139 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01533257 0,026732 ! peptide hormone processing GO:0016486 23 15 0,000 0,01533257 0,02671265 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01634661 0,02845872 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01634661 0,02843814 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01634661 0,02841759 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01634661 0,02839708 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01634661 0,02837659 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01634661 0,02835613 ! bone remodeling GO:0046849 27 16 0,000 0,01634661 0,0283357 ! filopodium assembly GO:0046847 32 16 0,000 0,01634661 0,0283153 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01634661 0,02829493 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01634661 0,02827459 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01634661 0,02825427 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01634661 0,02823399 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01634661 0,02821374 ! startle response GO:0001964 28 16 0,000 0,01634661 0,02819351 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01634661 0,02817332 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01634661 0,02815315 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01634661 0,02813301 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01634661 0,0281129 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01634661 0,02809282 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01634661 0,02807277 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01634661 0,02805275 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01634661 0,02803275 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01634661 0,02801278 ! response to osmotic stress GO:0006970 25 16 0,000 0,01634661 0,02799285 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01634661 0,02797294 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01634661 0,02795306 ! fructose metabolic process GO:0006000 25 16 0,000 0,01634661 0,0279332 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01634661 0,02791338 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01634661 0,02789358 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01634661 0,02787381 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01634661 0,02785407 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01634661 0,02783436 ! axon cargo transport GO:0008088 43 16 0,000 0,01634661 0,02781467 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01634661 0,02779502 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01634661 0,02777539 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01634661 0,02775579 ! DNA replication initiation GO:0006270 27 16 0,000 0,01634661 0,02773621 ! neuron recognition GO:0008038 35 16 0,000 0,01634661 0,02771667 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01634661 0,02769715 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01634661 0,02767766 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01634661 0,02765819 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01634661 0,02763876 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01634661 0,02761935 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01634661 0,02759996 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01634661 0,02758061 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01634661 0,02756128 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01634661 0,02754198 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01634661 0,02752271 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01634661 0,02750346 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01634661 0,02748424 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01634661 0,02746505 ! defense response to virus GO:0051607 37 16 0,000 0,01634661 0,02744588 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01735964 0,02912643 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01735964 0,02910613 ! metencephalon development GO:0022037 30 17 0,000 0,01735964 0,02908587 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01735964 0,02906563 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01735964 0,02904541 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01735964 0,02902523 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01735964 0,02900507 ! signal complex assembly GO:0007172 41 17 0,000 0,01735964 0,02898494 ! endothelial cell migration GO:0043542 28 17 0,000 0,01735964 0,02896484 ! inositol metabolic process GO:0006020 28 17 0,000 0,01735964 0,02894477 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01735964 0,02892473 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01735964 0,02890471 ! glial cell development GO:0021782 27 17 0,000 0,01735964 0,02888472 ! limbic system development GO:0021761 36 17 0,000 0,01735964 0,02886476 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01735964 0,02884482 ! adult walking behavior GO:0007628 33 17 0,000 0,01735964 0,02882492 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01735964 0,02880504 ! heart looping GO:0001947 30 17 0,000 0,01735964 0,02878518 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01735964 0,02876536 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01735964 0,02874556 ! myoblast differentiation GO:0045445 45 17 0,000 0,01735964 0,02872579 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01735964 0,02870605 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01735964 0,02868633 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01735964 0,02866665 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01735964 0,02864698 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01735964 0,02862735 ! glycine metabolic process GO:0006544 28 17 0,000 0,01735964 0,02860774 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01735964 0,02858816 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01735964 0,02856861 ! NAD metabolic process GO:0019674 29 17 0,000 0,01735964 0,02854908 ! membrane budding GO:0006900 37 17 0,000 0,01735964 0,02852958 ! DNA integration GO:0015074 29 17 0,000 0,01735964 0,0285101 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01735964 0,02849066 ! regulation of protein binding GO:0043393 33 17 0,000 0,01735964 0,02847124 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01735964 0,02845184 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01735964 0,02843247 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01735964 0,02841313 ! genitalia development GO:0048806 30 17 0,000 0,01735964 0,02839382 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01735964 0,02837453 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01735964 0,02835526 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01735964 0,02833603 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01735964 0,02831682 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01735964 0,02829763 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01735964 0,02827847 ! steroid catabolic process GO:0006706 31 17 0,000 0,01735964 0,02825934 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01735964 0,02824023 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01735964 0,02822115 ! gas transport GO:0015669 25 17 0,000 0,01735964 0,0282021 ! organic cation transport GO:0015695 31 17 0,000 0,01735964 0,02818307 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01735964 0,02816406 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01735964 0,02814508 ! microspike assembly GO:0030035 36 17 0,000 0,01735964 0,02812613 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01735964 0,0281072 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01837167 0,02972577 ! neuron maturation GO:0042551 42 18 0,000 0,01837167 0,0297058 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01837167 0,02968585 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01837167 0,02966592 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01837167 0,02964603 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01837167 0,02962616 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01837167 0,02960631 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01837167 0,0295865 ! memory GO:0007613 31 18 0,000 0,01837167 0,02956671 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01837167 0,02954694 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01837167 0,02952721 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01837167 0,02950749 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01837167 0,02948781 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01837167 0,02946815 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01837167 0,02944852 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01837167 0,02942891 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01837167 0,02940933 ! response to retinoic acid GO:0032526 26 18 0,000 0,01837167 0,02938978 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01837167 0,02937025 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01837167 0,02935075 ! response to fungus GO:0009620 21 18 0,000 0,01837167 0,02933127 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01837167 0,02931182 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01837167 0,0292924 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01837167 0,029273 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01837167 0,02925362 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01837167 0,02923428 ! vitamin transport GO:0051180 27 18 0,000 0,01837167 0,02921496 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01837167 0,02919566 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01837167 0,02917639 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01837167 0,02915714 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01837167 0,02913792 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01837167 0,02911873 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01837167 0,02909956 ! nerve development GO:0021675 28 18 0,000 0,01837167 0,02908041 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01837167 0,02906129 ! protein secretion GO:0009306 39 19 0,000 0,01938268 0,03064042 ! positive regulation of translation GO:0045727 30 19 0,000 0,01938268 0,0306203 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01938268 0,03060021 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01938268 0,03058015 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01938268 0,03056011 ! skin development GO:0043588 36 19 0,000 0,01938268 0,03054009 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01938268 0,03052011 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01938268 0,03050015 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01938268 0,03048021 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01938268 0,0304603 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01938268 0,03044042 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01938268 0,03042056 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01938268 0,03040073 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01938268 0,03038093 ! cerebral cortex development GO:0021987 36 19 0,000 0,01938268 0,03036115 ! pigmentation during development GO:0048066 41 19 0,000 0,01938268 0,0303414 ! response to vitamin A GO:0033189 27 19 0,000 0,01938268 0,03032167 ! heme metabolic process GO:0042168 36 19 0,000 0,01938268 0,03030197 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01938268 0,03028229 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01938268 0,03026264 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01938268 0,03024301 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01938268 0,03022341 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01938268 0,03020384 ! peptide cross-linking GO:0018149 37 19 0,000 0,01938268 0,03018429 ! protein export from nucleus GO:0006611 36 19 0,000 0,01938268 0,03016476 ! heart process GO:0003015 30 19 0,000 0,01938268 0,03014526 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01938268 0,03012579 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01938268 0,03010634 ! visual learning GO:0008542 36 19 0,000 0,01938268 0,03008692 ! cellular pigmentation GO:0033059 36 19 0,000 0,01938268 0,03006752 ! G1 phase GO:0051318 40 19 0,000 0,01938268 0,03004815 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01938268 0,0300288 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01938268 0,03000948 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01938268 0,02999018 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01938268 0,0299709 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01938268 0,02995165 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01938268 0,02993243 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01938268 0,02991323 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01938268 0,02989405 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01938268 0,0298749 ! cilium assembly GO:0042384 37 19 0,000 0,01938268 0,02985578 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01938268 0,02983668 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02039268 0,03137135 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02039268 0,03135131 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02039268 0,03133129 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02039268 0,03131129 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02039268 0,03129132 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02039268 0,03127138 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02039268 0,03125146 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02039268 0,03123157 ! response to vitamin GO:0033273 31 20 0,000 0,02039268 0,0312117 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02039268 0,03119186 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02039268 0,03117204 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02039268 0,03115225 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02039268 0,03113249 ! response to alkaloid GO:0043279 38 20 0,000 0,02039268 0,03111274 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02039268 0,03109303 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02039268 0,03107334 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02039268 0,03105367 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02039268 0,03103403 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02039268 0,03101441 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02039268 0,03099482 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02039268 0,03097525 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02039268 0,03095571 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02039268 0,03093619 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02039268 0,0309167 ! body fluid secretion GO:0007589 31 20 0,000 0,02039268 0,03089723 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02039268 0,03087778 ! peptide secretion GO:0002790 35 20 0,000 0,02039268 0,03085836 ! stem cell differentiation GO:0048863 53 20 0,000 0,02039268 0,03083897 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02039268 0,0308196 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02039268 0,03080025 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02039268 0,03078093 ! sensory perception of pain GO:0019233 30 20 0,000 0,02039268 0,03076163 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02039268 0,03074235 ! diencephalon development GO:0021536 34 20 0,000 0,02039268 0,0307231 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02039268 0,03070388 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02039268 0,03068468 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02039268 0,0306655 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02039268 0,03064634 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02039268 0,03062721 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02039268 0,03060811 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02039268 0,03058903 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02039268 0,03056997 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02039268 0,03055093 ! regulation of glucose import GO:0046324 29 20 0,000 0,02039268 0,03053192 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02039268 0,03051293 ! actin filament-based movement GO:0030048 43 20 0,000 0,02039268 0,03049397 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02039268 0,03047503 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02039268 0,03045611 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02039268 0,03043722 ! negative regulation of translation GO:0017148 29 20 0,000 0,02039268 0,03041835 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02039268 0,0303995 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02039268 0,03038068 ! regulation of cell killing GO:0031341 42 21 0,000 0,02140168 0,03186414 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02140168 0,03184443 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02140168 0,03182475 ! hormone secretion GO:0046879 38 21 0,000 0,02140168 0,03180509 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02140168 0,03178546 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02140168 0,03176585 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02140168 0,03174627 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02140168 0,03172671 ! axis specification GO:0009798 38 21 0,000 0,02140168 0,03170717 ! ovarian follicle development GO:0001541 35 21 0,000 0,02140168 0,03168766 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02140168 0,03166817 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02140168 0,03164871 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02140168 0,03162927 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02140168 0,03160985 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02140168 0,03159046 ! cell aging GO:0007569 44 21 0,000 0,02140168 0,03157109 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02140168 0,03155174 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02140168 0,03153242 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02140168 0,03151313 ! cytolysis GO:0019835 24 21 0,000 0,02140168 0,03149385 ! vasodilation GO:0042311 39 21 0,000 0,02140168 0,0314746 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02140168 0,03145537 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02140168 0,03143617 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02140168 0,03141699 ! oogenesis GO:0048477 36 21 0,000 0,02140168 0,03139783 ! DNA modification GO:0006304 34 21 0,000 0,02140168 0,0313787 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02140168 0,03135959 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02140168 0,0313405 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02140168 0,03132144 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02140168 0,0313024 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02140168 0,03128338 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02140168 0,03126439 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02140168 0,03124542 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02140168 0,03122647 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02140168 0,03120754 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02140168 0,03118864 ! collagen catabolic process GO:0030574 28 21 0,000 0,02140168 0,03116976 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02140168 0,03115091 ! gut development GO:0048565 39 21 0,000 0,02140168 0,03113207 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02240967 0,03257866 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02240967 0,03255898 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02240967 0,03253933 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02240967 0,03251971 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02240967 0,03250011 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02240967 0,03248053 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02240967 0,03246097 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02240967 0,03244144 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02240967 0,03242193 ! regeneration GO:0031099 41 22 0,000 0,02240967 0,03240245 ! keratinization GO:0031424 28 22 0,000 0,02240967 0,03238299 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02240967 0,03236355 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02240967 0,03234414 ! sensory perception of taste GO:0050909 28 22 0,000 0,02240967 0,03232475 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02240967 0,03230538 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02240967 0,03228603 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02240967 0,03226671 ! vacuolar transport GO:0007034 36 22 0,000 0,02240967 0,03224741 ! lysosome organization GO:0007040 41 22 0,000 0,02240967 0,03222814 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02240967 0,03220889 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02240967 0,03218966 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02240967 0,03217045 ! fucose metabolic process GO:0006004 39 22 0,000 0,02240967 0,03215127 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02240967 0,03213211 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02240967 0,03211297 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02240967 0,03209386 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02240967 0,03207476 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02240967 0,03205569 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02240967 0,03203665 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02240967 0,03201762 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02240967 0,03199862 ! sarcomere organization GO:0045214 30 22 0,000 0,02240967 0,03197964 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02240967 0,03196069 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02240967 0,03194175 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02240967 0,03192284 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02240967 0,03190395 ! protein stabilization GO:0050821 39 22 0,000 0,02240967 0,03188508 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02341666 0,03329816 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02341666 0,03327849 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02341666 0,03325885 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02341666 0,03323923 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02341666 0,03321963 ! gluconeogenesis GO:0006094 33 23 0,000 0,02341666 0,03320005 ! viral genome replication GO:0019079 41 23 0,000 0,02341666 0,0331805 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02341666 0,03316097 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02341666 0,03314146 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02341666 0,03312198 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02341666 0,03310252 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02341666 0,03308308 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02341666 0,03306367 ! visual behavior GO:0007632 42 23 0,000 0,02341666 0,03304428 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,02341666 0,03302491 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02341666 0,03300556 ! response to ethanol GO:0045471 46 23 0,000 0,02341666 0,03298624 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02341666 0,03296693 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02341666 0,03294766 ! peroxisome organization GO:0007031 37 23 0,000 0,02341666 0,0329284 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02341666 0,03290916 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02341666 0,03288995 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02341666 0,03287076 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02341666 0,0328516 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02341666 0,03283245 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02341666 0,03281333 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02341666 0,03279423 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02341666 0,03277515 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02341666 0,0327561 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02341666 0,03273707 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02341666 0,03271805 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02341666 0,03269907 ! fatty acid transport GO:0015908 44 23 0,000 0,02341666 0,0326801 ! platelet activation GO:0030168 37 23 0,000 0,02341666 0,03266115 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02341666 0,03264223 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02341666 0,03262333 ! hormone transport GO:0009914 40 23 0,000 0,02341666 0,03260445 ! cell-cell recognition GO:0009988 25 23 0,000 0,02341666 0,03258559 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02341666 0,03256676 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02341666 0,03254794 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02341666 0,03252915 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02341666 0,03251038 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02341666 0,03249163 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02442265 0,03386795 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02442265 0,03384844 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02442265 0,03382895 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02442265 0,03380949 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02442265 0,03379004 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02442265 0,03377063 ! vesicle docking GO:0048278 47 24 0,000 0,02442265 0,03375123 ! spinal cord development GO:0021510 47 24 0,000 0,02442265 0,03373185 ! vacuole organization GO:0007033 43 24 0,000 0,02442265 0,0337125 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02442265 0,03369317 ! digestive system process GO:0022600 39 24 0,000 0,02442265 0,03367386 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02442265 0,03365458 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02442265 0,03363531 ! regulation of behavior GO:0050795 43 24 0,000 0,02442265 0,03361607 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02442265 0,03359685 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02442265 0,03357765 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02442265 0,03355847 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02442265 0,03353932 ! membrane depolarization GO:0051899 39 24 0,000 0,02442265 0,03352019 ! pallium development GO:0021543 49 24 0,000 0,02442265 0,03350108 ! pentose metabolic process GO:0019321 35 24 0,000 0,02442265 0,03348199 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02442265 0,03346292 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02442265 0,03344387 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02442265 0,03342485 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02442265 0,03340585 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02442265 0,03338687 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02442265 0,03336791 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02442265 0,03334897 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02442265 0,03333006 ! regulation of amine transport GO:0051952 40 24 0,000 0,02442265 0,03331116 ! protein tetramerization GO:0051262 52 24 0,000 0,02442265 0,03329229 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02542763 0,03464262 ! myelination GO:0042552 45 25 0,000 0,02542763 0,03462302 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02542763 0,03460343 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02542763 0,03458387 ! phototransduction GO:0007602 33 25 0,000 0,02542763 0,03456433 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02542763 0,03454482 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02542763 0,03452532 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02542763 0,03450585 ! sperm motility GO:0030317 31 25 0,000 0,02542763 0,0344864 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02542763 0,03446697 ! receptor metabolic process GO:0043112 46 25 0,000 0,02542763 0,03444756 ! chromosome condensation GO:0030261 45 25 0,000 0,02542763 0,03442818 ! response to starvation GO:0042594 42 25 0,000 0,02542763 0,03440881 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02542763 0,03438947 ! neural crest cell development GO:0014032 54 25 0,000 0,02542763 0,03437015 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02542763 0,03435085 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02542763 0,03433158 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02542763 0,03431232 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02542763 0,03429309 ! interaction with host GO:0051701 62 25 0,000 0,02542763 0,03427388 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02542763 0,03425469 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02542763 0,03423552 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02542763 0,03421637 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02542763 0,03419725 ! immunoglobulin production GO:0002377 55 25 0,000 0,02542763 0,03417814 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02542763 0,03415906 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02542763 0,03414 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02542763 0,03412096 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02542763 0,03410194 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02542763 0,03408294 ! liver development GO:0001889 53 25 0,000 0,02542763 0,03406396 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02643161 0,03538923 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02643161 0,03536955 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02643161 0,03534989 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02643161 0,03533025 ! initiation of viral infection GO:0019059 57 26 0,000 0,02643161 0,03531063 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02643161 0,03529104 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02643161 0,03527146 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02643161 0,03525191 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02643161 0,03523238 ! molting cycle process GO:0022404 50 26 0,000 0,02643161 0,03521287 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02643161 0,03519339 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02643161 0,03517392 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02643161 0,03515448 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02643161 0,03513505 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02643161 0,03511565 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02643161 0,03509627 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02643161 0,03507691 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02643161 0,03505758 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02643161 0,03503826 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02643161 0,03501897 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02643161 0,0349997 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02643161 0,03498044 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02643161 0,03496121 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02643161 0,034942 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02643161 0,03492282 ! blastocyst development GO:0001824 49 26 0,000 0,02643161 0,03490365 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02643161 0,0348845 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02643161 0,03486538 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02643161 0,03484627 ! neuron fate commitment GO:0048663 48 27 0,000 0,02743459 0,03614875 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02743459 0,03612896 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02743459 0,0361092 ! iron ion transport GO:0006826 59 27 0,000 0,02743459 0,03608945 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02743459 0,03606973 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02743459 0,03605003 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02743459 0,03603036 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02743459 0,0360107 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02743459 0,03599106 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02743459 0,03597145 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02743459 0,03595186 ! autophagy GO:0006914 41 27 0,000 0,02743459 0,03593229 ! male gonad development GO:0008584 44 27 0,000 0,02743459 0,03591274 ! response to toxin GO:0009636 47 27 0,000 0,02743459 0,03589321 ! base-excision repair GO:0006284 41 27 0,000 0,02743459 0,0358737 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02743459 0,03585422 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02743459 0,03583475 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02743459 0,03581531 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02743459 0,03579589 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02743459 0,03577648 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02743459 0,0357571 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02843656 0,03704297 ! circadian rhythm GO:0007623 50 28 0,000 0,02843656 0,03702293 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02843656 0,03700291 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02843656 0,0369829 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02843656 0,03696292 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02843656 0,03694297 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02843656 0,03692303 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02843656 0,03690311 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02843656 0,03688322 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02843656 0,03686335 ! synaptogenesis GO:0007416 42 28 0,000 0,02843656 0,0368435 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02843656 0,03682367 ! lipid oxidation GO:0034440 43 28 0,000 0,02843656 0,03680386 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02843656 0,03678407 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02843656 0,03676431 ! translational initiation GO:0006413 65 29 0,000 0,02943754 0,03803799 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02943754 0,03801757 ! regulation of pH GO:0006885 43 29 0,000 0,02943754 0,03799717 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02943754 0,0379768 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02943754 0,03795645 ! catechol metabolic process GO:0009712 54 29 0,000 0,02943754 0,03793612 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02943754 0,03791581 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02943754 0,03789552 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02943754 0,03787526 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02943754 0,03785501 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02943754 0,03783479 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02943754 0,03781459 ! cell fate determination GO:0001709 60 29 0,000 0,02943754 0,03779441 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02943754 0,03777426 ! detection of light stimulus GO:0009583 38 29 0,000 0,02943754 0,03775412 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02943754 0,03773401 ! tissue homeostasis GO:0001894 48 29 0,000 0,02943754 0,03771391 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02943754 0,03769384 ! phenol metabolic process GO:0018958 55 30 0,000 0,03043752 0,03895356 ! zinc ion transport GO:0006829 45 30 0,000 0,03043752 0,03893285 ! membrane docking GO:0022406 61 30 0,000 0,03043752 0,03891216 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03043752 0,03889149 ! cell junction assembly GO:0034329 78 30 0,000 0,03043752 0,03887085 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03043752 0,03885023 ! acute-phase response GO:0006953 49 30 0,000 0,03043752 0,03882963 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03043752 0,03880905 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03043752 0,0387885 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03043752 0,03876796 ! phospholipid transport GO:0015914 51 30 0,000 0,03043752 0,03874745 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03043752 0,03872696 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03043752 0,03870649 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03043752 0,03868605 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03043752 0,03866562 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03043752 0,03864522 ! eye morphogenesis GO:0048592 60 30 0,000 0,03043752 0,03862483 ! response to heat GO:0009408 50 30 0,000 0,03043752 0,03860447 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03143651 0,03985049 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03143651 0,03982951 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03143651 0,03980855 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03143651 0,03978761 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,03143651 0,03976669 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03143651 0,03974579 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03143651 0,03972492 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03143651 0,03970406 ! ovulation cycle process GO:0022602 49 31 0,000 0,03143651 0,03968323 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03143651 0,03966242 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03143651 0,03964163 ! peptide transport GO:0015833 55 31 0,000 0,03143651 0,03962087 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03143651 0,03960013 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03143651 0,0395794 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03143651 0,0395587 ! mesoderm formation GO:0001707 69 31 0,000 0,03143651 0,03953802 ! natural killer cell activation GO:0030101 45 31 0,000 0,03143651 0,03951737 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03143651 0,03949673 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03143651 0,03947612 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03143651 0,03945552 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03143651 0,03943495 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03143651 0,0394144 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0324345 0,04064448 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0324345 0,04062332 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0324345 0,04060218 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0324345 0,04058107 ! cholesterol transport GO:0030301 56 32 0,000 0,0324345 0,04055998 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0324345 0,04053891 ! spliceosome assembly GO:0000245 67 32 0,000 0,0324345 0,04051786 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0324345 0,04049683 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0324345 0,04047583 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0324345 0,04045485 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0324345 0,04043389 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0324345 0,04041295 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0324345 0,04039203 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0324345 0,04037113 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0324345 0,04035026 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0324345 0,04032941 ! ovulation cycle GO:0042698 51 32 0,000 0,0324345 0,04030857 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0324345 0,04028776 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0324345 0,04026698 ! hindbrain development GO:0030902 61 32 0,000 0,0324345 0,04024621 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0324345 0,04022546 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0324345 0,04020474 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0324345 0,04018404 ! gene silencing GO:0016458 65 32 0,000 0,0324345 0,04016335 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03343149 0,04137663 ! post-embryonic development GO:0009791 69 33 0,000 0,03343149 0,04135535 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03343149 0,0413341 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03343149 0,04131287 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03343149 0,04129167 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03343149 0,04127048 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03343149 0,04124931 ! sterol transport GO:0015918 57 33 0,000 0,03343149 0,04122817 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03343149 0,04120705 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03343149 0,04118595 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03343149 0,04116487 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03343149 0,04114382 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03343149 0,04112278 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03442749 0,04232628 ! glial cell differentiation GO:0010001 63 34 0,000 0,03442749 0,04230467 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03442749 0,04228307 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03442749 0,0422615 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03442749 0,04223995 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03442749 0,04221842 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03442749 0,04219691 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03442749 0,04217543 ! mismatch repair GO:0006298 46 34 0,000 0,03442749 0,04215396 ! spermatid development GO:0007286 63 34 0,000 0,03442749 0,04213252 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03442749 0,0421111 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03442749 0,0420897 ! placenta development GO:0001890 53 34 0,000 0,03442749 0,04206833 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03442749 0,04204697 ! regulation of muscle development GO:0048634 70 35 0,000 0,03542249 0,04324024 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03542249 0,04321832 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03542249 0,04319641 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03542249 0,04317453 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03542249 0,04315267 ! odontogenesis GO:0042476 66 35 0,000 0,03542249 0,04313083 ! female gonad development GO:0008585 58 35 0,000 0,03542249 0,04310901 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03542249 0,04308722 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03542249 0,04306545 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,03542249 0,0430437 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03542249 0,04302197 ! cytokine production GO:0001816 59 35 0,000 0,03542249 0,04300026 ! vesicle localization GO:0051648 64 35 0,000 0,03542249 0,04297858 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03641651 0,04416236 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03641651 0,04414011 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03641651 0,04411788 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03641651 0,04409568 ! cell junction organization GO:0034330 86 36 0,000 0,03641651 0,0440735 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03641651 0,04405134 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03641651 0,0440292 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03641651 0,04400709 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03641651 0,043985 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03641651 0,04396293 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03641651 0,04394088 ! aerobic respiration GO:0009060 55 36 0,000 0,03641651 0,04391885 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03641651 0,04389685 ! embryonic organ development GO:0048568 57 36 0,000 0,03641651 0,04387487 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03641651 0,04385291 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03641651 0,04383097 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03740953 0,04500366 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03740953 0,04498117 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03740953 0,0449587 ! organic anion transport GO:0015711 68 37 0,000 0,03740953 0,04493626 ! tissue remodeling GO:0048771 76 37 0,000 0,03740953 0,04491383 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03740953 0,04489143 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03740953 0,04486906 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03740953 0,0448467 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03740953 0,04482437 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03740953 0,04480205 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03740953 0,04477976 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03740953 0,0447575 ! pigment metabolic process GO:0042440 80 37 0,000 0,03740953 0,04473525 ! spermatid differentiation GO:0048515 66 37 0,000 0,03740953 0,04471303 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03840156 0,04587594 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03840156 0,04585318 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03840156 0,04583043 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03840156 0,04580771 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03840156 0,04578501 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03840156 0,04576233 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03840156 0,04573968 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03840156 0,04571705 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03840156 0,04569444 ! lipid homeostasis GO:0055088 67 38 0,000 0,03840156 0,04567185 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03840156 0,04564929 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03840156 0,04562674 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03840156 0,04560422 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03840156 0,04558172 ! glucan metabolic process GO:0044042 62 38 0,000 0,03840156 0,04555925 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,0393926 0,04671198 ! mammary gland development GO:0030879 86 39 0,000 0,0393926 0,04668897 ! learning GO:0007612 77 39 0,000 0,0393926 0,04666598 ! organic ether metabolic process GO:0018904 55 39 0,000 0,0393926 0,04664301 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,0393926 0,04662007 ! segmentation GO:0035282 67 39 0,000 0,0393926 0,04659715 ! ion transmembrane transport GO:0034220 66 39 0,000 0,0393926 0,04657425 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,0393926 0,04655138 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,0393926 0,04652852 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,0393926 0,04650569 ! RNA modification GO:0009451 57 39 0,000 0,0393926 0,04648288 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,0393926 0,0464601 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04038266 0,04760444 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04038266 0,04758113 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04038266 0,04755784 ! feeding behavior GO:0007631 59 40 0,000 0,04038266 0,04753457 ! negative regulation of binding GO:0051100 72 40 0,000 0,04038266 0,04751133 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,04038266 0,04748811 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04038266 0,04746491 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04038266 0,04744173 ! maintenance of protein location GO:0045185 91 40 0,000 0,04038266 0,04741858 ! cytokinesis GO:0000910 72 40 0,000 0,04038266 0,04739545 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04137172 0,0485326 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04137172 0,04850895 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04137172 0,04848532 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04137172 0,04846171 ! gliogenesis GO:0042063 88 41 0,000 0,04137172 0,04843813 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04137172 0,04841457 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04137172 0,04839104 ! T cell differentiation GO:0030217 81 41 0,000 0,04137172 0,04836752 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,04137172 0,04834403 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04137172 0,04832056 ! female gamete generation GO:0007292 61 41 0,000 0,04137172 0,04829712 ! polyol metabolic process GO:0019751 66 41 0,000 0,04137172 0,0482737 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04137172 0,0482503 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0423598 0,04937872 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0423598 0,04935481 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,0423598 0,04933092 ! regulation of tube size GO:0035150 71 42 0,000 0,0423598 0,04930705 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0423598 0,04928321 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0423598 0,04925939 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0423598 0,04923559 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,0423598 0,04921182 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0423598 0,04918807 ! neuron migration GO:0001764 79 42 0,000 0,0423598 0,04916434 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0423598 0,04914064 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0423598 0,04911695 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04334689 0,0502373 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04334689 0,05021311 ! glucose transport GO:0015758 65 43 0,000 0,04334689 0,05018895 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04334689 0,0501648 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04334689 0,05014069 ! striated muscle contraction GO:0006941 77 43 0,000 0,04334689 0,05011659 ! phagocytosis GO:0006909 90 43 0,000 0,04334689 0,05009252 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04334689 0,05006847 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,044333 0,05118292 ! hexose transport GO:0008645 67 44 0,000 0,044333 0,05115837 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,044333 0,05113385 ! male sex differentiation GO:0046661 76 44 0,000 0,044333 0,05110935 ! double-strand break repair GO:0006302 81 44 0,000 0,044333 0,05108487 ! biopolymer methylation GO:0043414 84 44 0,000 0,044333 0,05106041 ! B cell differentiation GO:0030183 107 44 0,000 0,044333 0,05103598 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,044333 0,05101158 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,044333 0,05098719 ! developmental growth GO:0048589 82 44 0,000 0,044333 0,05096283 ! maintenance of location in cell GO:0051651 97 44 0,000 0,044333 0,05093849 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,04531813 0,05204555 ! glycolysis GO:0006096 65 45 0,000 0,04531813 0,05202071 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,04531813 0,05199591 ! leukocyte migration GO:0050900 68 45 0,000 0,04531813 0,05197112 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,04531813 0,05194636 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,04531813 0,05192163 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,04531813 0,05189692 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,04531813 0,05187223 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,04531813 0,05184756 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,04531813 0,05182292 ! cell growth GO:0016049 84 45 0,000 0,04531813 0,0517983 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,04630227 0,05289804 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,04630227 0,05287293 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,04630227 0,05284785 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,04630227 0,05282279 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,04630227 0,05279776 ! pigmentation GO:0043473 100 46 0,000 0,04630227 0,05277275 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,04630227 0,05274776 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04728543 0,05384229 ! endosome transport GO:0016197 108 47 0,000 0,04728543 0,05381682 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04728543 0,05379137 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04728543 0,05376595 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04728543 0,05374055 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04728543 0,05371518 ! JNK cascade GO:0007254 91 47 0,000 0,04728543 0,05368983 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,04728543 0,05366451 ! methylation GO:0032259 90 47 0,000 0,04728543 0,0536392 ! protein homooligomerization GO:0051260 76 47 0,000 0,04728543 0,05361393 ! mitochondrial transport GO:0006839 82 48 0,000 0,04826761 0,05470178 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04826761 0,05467602 ! cellular component disassembly GO:0022411 86 48 0,000 0,04826761 0,05465029 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04826761 0,05462459 ! activation of caspase activity GO:0006919 84 48 0,000 0,04826761 0,05459891 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04826761 0,05457325 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04826761 0,05454762 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04826761 0,05452201 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04924881 0,05560424 ! regulation of action potential GO:0001508 95 49 0,000 0,04924881 0,05557816 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04924881 0,05555211 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04924881 0,05552607 ! regulation of ion transport GO:0043269 77 49 0,000 0,04924881 0,05550007 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04924881 0,05547408 ! peptide metabolic process GO:0006518 76 49 0,000 0,04924881 0,05544812 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04924881 0,05542219 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04924881 0,05539628 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04924881 0,05537039 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04924881 0,05534453 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04924881 0,05531869 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04924881 0,05529288 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,05022903 0,0563671 ! neuromuscular process GO:0050905 99 50 0,000 0,05022903 0,05634082 ! regulation of ossification GO:0030278 117 50 0,000 0,05022903 0,05631456 ! histone modification GO:0016570 91 50 0,000 0,05022903 0,05628833 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05022903 0,05626213 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05022903 0,05623595 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05022903 0,05620979 ! positive regulation of binding GO:0051099 78 51 0,000 0,05120828 0,05727899 ! viral infectious cycle GO:0019058 99 51 0,000 0,05120828 0,05725238 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,05120828 0,05722578 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,05120828 0,05719922 ! excretion GO:0007588 83 51 0,000 0,05120828 0,05717267 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,05120828 0,05714616 ! chromatin remodeling GO:0006338 109 51 0,000 0,05120828 0,05711966 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,05120828 0,05709319 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,05120828 0,05706675 ! vesicle organization GO:0016050 107 51 0,000 0,05120828 0,05704033 ! regulation of cell shape GO:0008360 125 51 0,000 0,05120828 0,05701394 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,05218654 0,05807624 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,05218654 0,05804939 ! membrane fusion GO:0006944 110 52 0,000 0,05218654 0,05802256 ! positive regulation of growth GO:0045927 90 52 0,000 0,05218654 0,05799576 ! covalent chromatin modification GO:0016569 101 52 0,000 0,05218654 0,05796898 ! amino acid activation GO:0043038 92 52 0,000 0,05218654 0,05794223 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,05218654 0,05791551 ! synapse organization GO:0050808 85 52 0,000 0,05218654 0,05788881 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,05316383 0,05894571 ! RNA catabolic process GO:0006401 93 53 0,000 0,05316383 0,05891855 ! regulation of translational initiation GO:0006446 82 53 0,000 0,05316383 0,05889143 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,05316383 0,05886433 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,05316383 0,05883725 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,05316383 0,0588102 ! cell maturation GO:0048469 100 53 0,000 0,05316383 0,05878317 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,05316383 0,05875617 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05414015 0,05980771 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05414015 0,05978026 ! cell recognition GO:0008037 85 54 0,000 0,05414015 0,05975284 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05414015 0,05972544 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05414015 0,05969807 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05414015 0,05967073 ! chloride transport GO:0006821 90 55 0,000 0,05511549 0,06071789 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,05511549 0,0606901 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,05511549 0,06066233 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,05511549 0,0606346 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,05511549 0,06060688 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,05511549 0,0605792 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,05511549 0,06055154 ! aging GO:0007568 103 55 0,000 0,05511549 0,0605239 ! gastrulation GO:0007369 112 55 0,000 0,05511549 0,06049629 ! heart morphogenesis GO:0003007 97 55 0,000 0,05511549 0,0604687 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,05511549 0,06044114 ! RNA elongation GO:0006354 79 55 0,000 0,05511549 0,0604136 ! nuclear export GO:0051168 97 55 0,000 0,05511549 0,06038609 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,05511549 0,06035861 ! regulation of actin filament length GO:0030832 105 56 0,000 0,05608985 0,06139772 ! sensory perception of smell GO:0007608 80 56 0,000 0,05608985 0,0613698 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,05608985 0,0613419 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,05608985 0,06131403 ! proton transport GO:0015992 94 56 0,000 0,05608985 0,06128619 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,05608985 0,06125837 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,05706325 0,06229318 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,05706325 0,06226493 ! lipid modification GO:0030258 97 57 0,000 0,05706325 0,06223671 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,05706325 0,06220851 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,05706325 0,06218033 ! maintenance of location GO:0051235 118 57 0,000 0,05706325 0,06215218 ! hydrogen transport GO:0006818 97 58 0,000 0,05803567 0,06318273 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05803567 0,06315415 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05803567 0,0631256 ! adult behavior GO:0030534 99 58 0,000 0,05803567 0,06309707 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05803567 0,06306858 ! positive regulation of secretion GO:0051047 95 59 0,000 0,05900712 0,06409532 ! regulation of cellular component size GO:0032535 109 59 0,000 0,05900712 0,0640664 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,05900712 0,0640375 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,05900712 0,06400863 ! DNA catabolic process GO:0006308 86 59 0,000 0,05900712 0,06397978 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,05900712 0,06395096 ! establishment of organelle localization GO:0051656 109 59 0,000 0,05900712 0,06392217 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05997761 0,06494425 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,05997761 0,06491504 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05997761 0,06488585 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05997761 0,06485668 ! camera-type eye development GO:0043010 116 60 0,000 0,05997761 0,06482755 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05997761 0,06479844 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05997761 0,06476936 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,06094712 0,0657868 ! mesoderm development GO:0007498 119 61 0,000 0,06094712 0,0657573 ! tRNA processing GO:0008033 89 61 0,000 0,06094712 0,06572782 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,06094712 0,06569838 ! viral reproductive process GO:0022415 126 62 0,000 0,06191567 0,06671254 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,06191567 0,06668268 ! gonad development GO:0008406 98 62 0,000 0,06191567 0,06665284 ! regulation of mitosis GO:0007088 105 63 0,000 0,06288325 0,06766418 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,06288325 0,06763393 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,06288325 0,06760371 ! detection of external stimulus GO:0009581 91 63 0,000 0,06288325 0,06757351 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,06288325 0,06754335 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,06288325 0,06751321 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,06384986 0,06852041 ! cell redox homeostasis GO:0045454 102 64 0,000 0,06384986 0,06848987 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,06384986 0,06845934 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,06384986 0,06842885 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 0,000 0,06384986 0,06839838 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,06481551 0,06940192 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,06481551 0,06937105 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,06481551 0,06934021 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,06481551 0,06930939 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,06481551 0,0692786 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,0657802 0,07027849 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,0657802 0,07024729 ! extracellular matrix organization GO:0030198 133 66 0,000 0,0657802 0,07021613 ! secondary metabolic process GO:0019748 116 66 0,000 0,0657802 0,07018499 ! developmental maturation GO:0021700 116 66 0,000 0,0657802 0,07015388 ! cell projection assembly GO:0030031 120 66 0,000 0,0657802 0,0701228 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,06674392 0,07111863 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,06674392 0,07108715 ! activation of MAPK activity GO:0000187 115 67 0,000 0,06674392 0,07105569 ! lung development GO:0030324 144 67 0,000 0,06674392 0,07102427 ! chromosome segregation GO:0007059 113 67 0,000 0,06674392 0,07099287 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,06674392 0,0709615 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,06674392 0,07093015 ! hexose catabolic process GO:0019320 104 67 0,000 0,06674392 0,07089884 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,06674392 0,07086755 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,06674392 0,07083629 ! adaptive immune response GO:0002250 119 67 0,000 0,06674392 0,07080506 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,06674392 0,07077385 ! amino acid transport GO:0006865 125 68 0,000 0,06770668 0,07176311 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,06770668 0,07173151 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,06770668 0,07169994 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,06770668 0,0716684 ! viral reproduction GO:0016032 134 68 0,000 0,06770668 0,07163688 ! regulation of lipase activity GO:0060191 130 68 0,000 0,06770668 0,07160539 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,06770668 0,07157393 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,06866848 0,07255879 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06866848 0,07252694 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06866848 0,07249511 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06866848 0,07246331 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06866848 0,07243155 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06962932 0,07341286 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,06962932 0,0733807 ! amine catabolic process GO:0009310 117 71 0,000 0,0705892 0,07435972 ! reproductive structure development GO:0048608 113 71 0,000 0,0705892 0,07432718 ! appendage development GO:0048736 136 71 0,000 0,0705892 0,07429467 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,0705892 0,07426218 ! B cell activation GO:0042113 160 71 0,000 0,0705892 0,07422972 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,0705892 0,07419729 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0705892 0,07416489 ! acute inflammatory response GO:0002526 113 72 0,000 0,07154812 0,07513958 ! regulation of caspase activity GO:0043281 122 72 0,000 0,07154812 0,07510679 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,07154812 0,07507404 ! carbohydrate transport GO:0008643 110 72 0,000 0,07154812 0,07504131 ! respiratory system development GO:0060541 153 72 0,000 0,07154812 0,07500861 ! learning or memory GO:0007611 147 73 0,000 0,07250608 0,0759798 ! regulation of blood pressure GO:0008217 125 73 0,000 0,07250608 0,07594673 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,07250608 0,07591368 ! axon guidance GO:0007411 139 73 0,000 0,07250608 0,07588066 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,07346309 0,07684878 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,07346309 0,07681538 ! neurotransmitter transport GO:0006836 123 74 0,000 0,07346309 0,07678201 ! exocytosis GO:0006887 133 74 0,000 0,07346309 0,07674867 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,07346309 0,07671536 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,07346309 0,07668208 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,07346309 0,07664882 ! eye development GO:0001654 143 74 0,000 0,07346309 0,0766156 ! organelle localization GO:0051640 136 74 0,000 0,07346309 0,0765824 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,07441914 0,07754545 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,07441914 0,07751188 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,07441914 0,07747834 ! rhythmic process GO:0048511 128 75 0,000 0,07441914 0,07744483 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,07441914 0,07741135 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,07537423 0,07837096 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,07537423 0,07833711 ! defense response to bacterium GO:0042742 89 76 0,000 0,07537423 0,07830328 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,07537423 0,07826949 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,07537423 0,07823572 ! regulation of catabolic process GO:0009894 161 76 0,000 0,07537423 0,07820199 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,07632838 0,07915779 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,07632838 0,07912369 ! blood coagulation GO:0007596 146 78 0,000 0,07728157 0,08007728 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,07728157 0,08004281 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,07728157 0,08000837 ! protein oligomerization GO:0051259 139 78 0,000 0,07728157 0,07997396 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,0782338 0,08092456 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,0782338 0,08088979 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,0782338 0,08085504 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,0782338 0,08082032 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,0782338 0,08078564 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,07918509 0,08173287 ! protein import into nucleus GO:0006606 158 80 0,000 0,07918509 0,08169783 ! inorganic anion transport GO:0015698 138 80 0,000 0,07918509 0,08166281 ! T cell activation GO:0042110 168 81 0,000 0,08013543 0,08260747 ! response to hypoxia GO:0001666 171 81 0,000 0,08013543 0,08257209 ! digestion GO:0007586 112 81 0,000 0,08013543 0,08253675 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,08013543 0,08250143 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,08013543 0,08246614 ! nuclear import GO:0051170 161 81 0,000 0,08013543 0,08243088 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,08108482 0,08337182 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,08108482 0,08333621 ! response to drug GO:0042493 143 82 0,000 0,08108482 0,08330063 ! response to nutrient GO:0007584 125 82 0,000 0,08108482 0,08326507 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,08108482 0,08322955 ! response to oxygen levels GO:0070482 176 83 0,000 0,08203325 0,08416717 ! regulation of lyase activity GO:0051339 160 83 0,000 0,08203325 0,08413129 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,08298075 0,08506676 ! hemostasis GO:0007599 158 84 0,000 0,08298075 0,08503053 ! negative regulation of transport GO:0051051 153 84 0,000 0,08298075 0,08499433 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,08298075 0,08495816 ! nucleosome assembly GO:0006334 122 85 0,000 0,08392729 0,08589071 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,08392729 0,08585419 ! amine biosynthetic process GO:0009309 138 86 0,000 0,08487289 0,08678461 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,08487289 0,08674774 ! chromatin assembly GO:0031497 124 86 0,000 0,08487289 0,0867109 ! mitochondrion organization GO:0007005 148 86 0,000 0,08487289 0,0866741 ! alcohol catabolic process GO:0046164 130 86 0,000 0,08487289 0,08663733 ! amine transport GO:0015837 155 86 0,000 0,08487289 0,08660058 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,08581755 0,08752735 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,08581755 0,08749026 ! protein localization in nucleus GO:0034504 176 87 0,000 0,08581755 0,08745321 ! regulation of protein transport GO:0051223 154 87 0,000 0,08581755 0,08741618 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,08676126 0,08834007 ! regulation of DNA binding GO:0051101 155 88 0,000 0,08676126 0,0883027 ! regulation of neurological system process GO:0031644 148 88 0,000 0,08676126 0,08826536 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,08676126 0,08822806 ! cellular defense response GO:0006968 114 89 0,000 0,08770403 0,08914909 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,08770403 0,08911144 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,08770403 0,08907382 ! ossification GO:0001503 188 90 0,000 0,08864585 0,08999237 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,08864585 0,08995442 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,08864585 0,08991649 ! sex differentiation GO:0007548 145 90 0,000 0,08864585 0,0898786 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,08864585 0,08984074 ! bone development GO:0060348 189 91 0,000 0,08958674 0,09075608 ! sterol metabolic process GO:0016125 152 91 0,000 0,08958674 0,09071789 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,08958674 0,09067972 ! regulation of defense response GO:0031347 149 92 0,000 0,09052669 0,0915926 ! nucleosome organization GO:0034728 138 92 0,000 0,09052669 0,0915541 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,09052669 0,09151563 ! vitamin metabolic process GO:0006766 139 92 0,000 0,09052669 0,0914772 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,09146569 0,09238726 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,09146569 0,09234849 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,09146569 0,09230975 ! regulation of membrane potential GO:0042391 164 93 0,000 0,09146569 0,09227105 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,09146569 0,09223238 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,09240376 0,09313927 ! female pregnancy GO:0007565 164 94 0,000 0,09240376 0,09310027 ! transcription initiation GO:0006352 153 94 0,000 0,09240376 0,0930613 ! regulation of T cell activation GO:0050863 158 94 0,000 0,09240376 0,09302236 ! forebrain development GO:0030900 188 95 0,000 0,09334089 0,09392647 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,09334089 0,0938872 ! leukocyte differentiation GO:0002521 202 96 0,000 0,09427709 0,09478925 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,09427709 0,09474965 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,09427709 0,09471009 ! positive regulation of immune response GO:0050778 156 96 0,000 0,09427709 0,09467056 ! detection of stimulus GO:0051606 151 96 0,000 0,09427709 0,09463107 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,09521234 0,09552998 ! protein ubiquitination GO:0016567 217 97 0,000 0,09521234 0,09549016 ! hormone metabolic process GO:0042445 157 97 0,000 0,09521234 0,09545038 ! regulation of protein localization GO:0032880 176 97 0,000 0,09521234 0,09541062 ! response to virus GO:0009615 160 98 0,000 0,09614667 0,09630678 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,09614667 0,0962667 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,09614667 0,09622666 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,09708006 0,09712043 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,09708006 0,09708006