pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/6929-8-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! B cell lineage commitment GO:0002326 21 7 2,000 2,097E-08 5,124E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,81E-07 2,211E-04 ! B cell differentiation GO:0030183 124 45 2,000 8,314E-06 6,771E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 8,889E-06 5,429E-03 ! response to UV GO:0009411 120 55 2,000 1,528E-05 7,466E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,054E-05 8,365E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,298E-05 0,01151093 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,298E-05 0,01007206 ! B cell activation GO:0042113 179 72 2,000 3,439E-05 9,335E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 3,734E-05 9,121E-03 ! thymus development GO:0048538 29 11 1,000 4,029E-05 8,948E-03 ! lymphocyte differentiation GO:0030098 193 76 2,000 4,044E-05 8,234E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,832E-05 9,081E-03 ! T cell homeostasis GO:0043029 28 12 1,000 4,832E-05 8,432E-03 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 4,894E-05 7,971E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 5,264E-05 8,038E-03 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of protein modification process GO:0031401 156 90 2,000 6,703E-05 9,633E-03 ! response to unfolded protein GO:0006986 139 90 2,000 6,703E-05 9,097E-03 ! lymphocyte homeostasis GO:0002260 33 15 1,000 7,675E-05 9,868E-03 ! response to protein stimulus GO:0051789 158 96 2,000 8,123E-05 9,923E-03 ! leukocyte differentiation GO:0002521 232 98 2,000 8,637E-05 0,0100479 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 8,637E-05 9,591E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,385E-04 0,01471161 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,682E-04 0,01712233 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 1,841E-04 0,01799312 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 2,008E-04 0,01886365 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,008E-04 0,01816499 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,181E-04 0,01902905 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,181E-04 0,01837288 ! leukocyte homeostasis GO:0001776 50 25 1,000 2,181E-04 0,01776045 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 2,361E-04 0,01860971 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,361E-04 0,01802815 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,361E-04 0,01748185 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,744E-04 0,01971327 ! fat cell differentiation GO:0045444 57 28 1,000 2,744E-04 0,01915003 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,945E-04 0,01998634 ! regulation of B cell activation GO:0050864 55 30 1,000 3,154E-04 0,02082386 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,37E-04 0,02166243 ! response to heat GO:0009408 54 31 1,000 3,37E-04 0,02110698 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 3,592E-04 0,02193934 ! spindle organization GO:0007051 50 32 1,000 3,592E-04 0,02140423 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 4,553E-04 0,02648191 ! meiosis I GO:0007127 74 38 1,000 5,075E-04 0,02883189 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 5,075E-04 0,02817662 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 5,346E-04 0,02902391 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 6,202E-04 0,0329373 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 7,119E-04 0,03700603 ! positive regulation of cell cycle GO:0045787 96 48 1,000 8,099E-04 0,04121882 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 8,099E-04 0,04037762 ! JAK-STAT cascade GO:0007259 82 48 1,000 8,099E-04 0,03957007 ! response to calcium ion GO:0051592 94 49 1,000 8,439E-04 0,04042305 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 8,439E-04 0,03964568 ! response to temperature stimulus GO:0009266 84 51 1,000 9,139E-04 0,04212643 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 9,867E-04 0,04463796 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 9,867E-04 0,04382636 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of translational initiation GO:0006446 87 54 1,000 1,024E-03 0,04467502 ! mesoderm development GO:0007498 128 63 1,000 1,391E-03 0,05961004 ! negative regulation of cell growth GO:0030308 142 67 1,000 1,571E-03 0,0661775 ! negative regulation of cell size GO:0045792 144 69 1,000 1,665E-03 0,06895321 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 1,665E-03 0,06780399 ! homeostasis of number of cells GO:0048872 131 69 1,000 1,665E-03 0,06669245 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 1,665E-03 0,06561676 ! negative regulation of kinase activity GO:0033673 145 70 1,000 1,713E-03 0,06643845 ! negative regulation of transferase activity GO:0051348 155 74 1,000 1,912E-03 0,07298699 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 1,963E-03 0,07379297 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 2,121E-03 0,0785182 ! meiosis GO:0007126 143 81 1,000 2,285E-03 0,08331493 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 1,000 2,341E-03 0,08409635 ! response to metal ion GO:0010038 158 84 1,000 2,454E-03 0,08690098 ! negative regulation of growth GO:0045926 168 85 1,000 2,512E-03 0,08767609 ! positive regulation of cell activation GO:0050867 161 86 1,000 2,571E-03 0,08845139 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 173 90 1,000 2,811E-03 0,09536836 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 4,353E-03 0,14569104 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 4,353E-03 0,14372225 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 4,353E-03 0,14180595 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,353E-03 0,13994008 ! positive regulation of helicase activity GO:0051096 12 5 0,000 4,353E-03 0,13812268 ! neuron fate determination GO:0048664 7 5 0,000 4,353E-03 0,13635187 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,353E-03 0,1346259 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 4,353E-03 0,13294308 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 4,353E-03 0,1313018 ! polyol transport GO:0015791 12 5 0,000 4,353E-03 0,12970056 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,353E-03 0,12813791 ! response to superoxide GO:0000303 10 5 0,000 4,353E-03 0,12661245 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,353E-03 0,1251229 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 4,353E-03 0,12366798 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 4,353E-03 0,12224651 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,353E-03 0,12085734 ! female meiosis GO:0007143 10 5 0,000 4,353E-03 0,1194994 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,353E-03 0,11817162 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,353E-03 0,11687303 ! hypothalamus development GO:0021854 9 5 0,000 4,353E-03 0,11560268 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 4,353E-03 0,11435964 ! cobalt ion transport GO:0006824 11 5 0,000 4,353E-03 0,11314304 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 4,353E-03 0,11195206 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 4,353E-03 0,1107859 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,353E-03 0,10964377 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,353E-03 0,10852496 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 4,353E-03 0,10742875 ! embryonic camera-type eye development GO:0031076 12 5 0,000 4,353E-03 0,10635446 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,353E-03 0,10530145 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,353E-03 0,10426908 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 4,353E-03 0,10325676 ! transposition GO:0032196 9 5 0,000 4,353E-03 0,10226391 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 4,353E-03 0,10128996 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 4,353E-03 0,1003344 ! negative chemotaxis GO:0050919 16 5 0,000 4,353E-03 0,09939669 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,353E-03 0,09847635 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,353E-03 0,0975729 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 4,353E-03 0,09668587 ! behavioral response to pain GO:0048266 10 5 0,000 4,353E-03 0,09581483 ! clathrin coat assembly GO:0048268 15 5 0,000 4,353E-03 0,09495934 ! Notch receptor processing GO:0007220 11 5 0,000 4,353E-03 0,09411899 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,353E-03 0,09329339 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 4,353E-03 0,09248214 ! micturition GO:0060073 9 5 0,000 4,353E-03 0,09168488 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,353E-03 0,09090125 ! copulation GO:0007620 9 5 0,000 4,353E-03 0,0901309 ! glial cell fate commitment GO:0021781 14 5 0,000 4,353E-03 0,0893735 ! protein maturation by protein folding GO:0022417 14 5 0,000 4,353E-03 0,08862872 ! bioluminescence GO:0008218 9 5 0,000 4,353E-03 0,08789625 ! spermidine metabolic process GO:0008216 7 5 0,000 4,353E-03 0,08717579 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,353E-03 0,08646704 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,353E-03 0,08576973 ! apoptotic cell clearance GO:0043277 23 5 0,000 4,353E-03 0,08508357 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,353E-03 0,0844083 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 4,353E-03 0,08374367 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,353E-03 0,08308942 ! grooming behavior GO:0007625 6 5 0,000 4,353E-03 0,08244532 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 4,353E-03 0,08181112 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,353E-03 0,08118661 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 4,353E-03 0,08057156 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,353E-03 0,07996576 ! response to protozoan GO:0001562 13 5 0,000 4,353E-03 0,079369 ! positive regulation of glycolysis GO:0045821 13 5 0,000 4,353E-03 0,07878108 ! lymph vessel development GO:0001945 10 5 0,000 4,353E-03 0,07820181 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 4,353E-03 0,07763099 ! endochondral ossification GO:0001958 17 5 0,000 4,353E-03 0,07706845 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,353E-03 0,076514 ! single strand break repair GO:0000012 8 5 0,000 4,353E-03 0,07596747 ! parathyroid gland development GO:0060017 14 5 0,000 4,353E-03 0,0754287 ! anagen GO:0042640 7 5 0,000 4,353E-03 0,07489751 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,353E-03 0,07437375 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,353E-03 0,07385727 ! cytokine secretion GO:0050663 15 5 0,000 4,353E-03 0,0733479 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 4,353E-03 0,07284552 ! ceramide catabolic process GO:0046514 7 5 0,000 4,353E-03 0,07234997 ! skeletal myofibril assembly GO:0014866 12 5 0,000 4,353E-03 0,07186112 ! smooth muscle tissue development GO:0048745 32 5 0,000 4,353E-03 0,07137883 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,353E-03 0,07090297 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,353E-03 0,07043342 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,353E-03 0,06997004 ! cardiac muscle fiber development GO:0048739 12 5 0,000 4,353E-03 0,06951272 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,353E-03 0,06906134 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 4,353E-03 0,06861578 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,353E-03 0,06817594 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 4,353E-03 0,0677417 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,353E-03 0,06731295 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,353E-03 0,0668896 ! glycine biosynthetic process GO:0006545 7 5 0,000 4,353E-03 0,06647154 ! microvillus organization GO:0032528 8 5 0,000 4,353E-03 0,06605867 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 4,353E-03 0,0656509 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 4,353E-03 0,06524814 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 4,353E-03 0,06485028 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 4,353E-03 0,06445725 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 4,353E-03 0,06406895 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 4,353E-03 0,06368531 ! polyol catabolic process GO:0046174 9 5 0,000 4,353E-03 0,06330623 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,353E-03 0,06293163 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 4,353E-03 0,06256145 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,353E-03 0,06219559 ! muscle cell migration GO:0014812 8 5 0,000 4,353E-03 0,06183399 ! mitochondrial fission GO:0000266 8 5 0,000 4,353E-03 0,06147657 ! sister chromatid cohesion GO:0007062 15 5 0,000 4,353E-03 0,06112325 ! response to tumor necrosis factor GO:0034612 10 5 0,000 4,353E-03 0,06077398 ! mRNA transcription GO:0009299 10 5 0,000 4,353E-03 0,06042867 ! nerve growth factor processing GO:0032455 9 5 0,000 4,353E-03 0,06008727 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 4,353E-03 0,0597497 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 4,353E-03 0,0594159 ! anaerobic glycolysis GO:0019642 6 5 0,000 4,353E-03 0,05908581 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,353E-03 0,05875937 ! monocyte activation GO:0042117 10 5 0,000 4,353E-03 0,05843652 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,353E-03 0,05811719 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,353E-03 0,05780134 ! response to food GO:0032094 6 5 0,000 4,353E-03 0,0574889 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,353E-03 0,05717982 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,353E-03 0,05687404 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 4,353E-03 0,05657152 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,353E-03 0,0562722 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 4,353E-03 0,05597603 ! forebrain neuron development GO:0021884 13 5 0,000 4,353E-03 0,05568296 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,353E-03 0,05539295 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 4,353E-03 0,05510594 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 4,353E-03 0,05482189 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,353E-03 0,05454075 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,353E-03 0,05426248 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 4,353E-03 0,05398704 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,353E-03 0,05371437 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 4,353E-03 0,05344445 ! lipid glycosylation GO:0030259 7 5 0,000 4,353E-03 0,05317723 ! nucleobase transport GO:0015851 6 5 0,000 4,353E-03 0,05291267 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,353E-03 0,05265072 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 4,353E-03 0,05239136 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 4,353E-03 0,05213454 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 4,353E-03 0,05188023 ! basic amino acid transport GO:0015802 12 5 0,000 4,353E-03 0,05162838 ! cellular glucose homeostasis GO:0001678 6 5 0,000 4,353E-03 0,05137897 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 4,353E-03 0,05113195 ! actin nucleation GO:0045010 11 5 0,000 4,353E-03 0,0508873 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,353E-03 0,05064498 ! depurination GO:0045007 5 5 0,000 4,353E-03 0,05040496 ! depyrimidination GO:0045008 10 5 0,000 4,353E-03 0,0501672 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,353E-03 0,04993167 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,353E-03 0,04969835 ! G2/M transition checkpoint GO:0031576 8 5 0,000 4,353E-03 0,04946719 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,353E-03 0,04923818 ! zinc ion homeostasis GO:0055069 9 5 0,000 4,353E-03 0,04901127 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 4,353E-03 0,04878645 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 4,353E-03 0,04856368 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,353E-03 0,04834294 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,353E-03 0,04812419 ! activated T cell proliferation GO:0050798 16 5 0,000 4,353E-03 0,04790742 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,353E-03 0,04769258 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 4,353E-03 0,04747967 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,353E-03 0,04726865 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,353E-03 0,0470595 ! gamma-delta T cell activation GO:0046629 6 5 0,000 4,353E-03 0,04685219 ! response to arsenic GO:0046685 11 5 0,000 4,353E-03 0,04664669 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 4,353E-03 0,046443 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,353E-03 0,04624107 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 4,353E-03 0,04604089 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 4,353E-03 0,04584244 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 4,353E-03 0,04564569 ! response to mercury ion GO:0046689 8 5 0,000 4,353E-03 0,04545062 ! response to cadmium ion GO:0046686 7 5 0,000 4,353E-03 0,04525722 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 4,353E-03 0,04506545 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 4,353E-03 0,0448753 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 4,353E-03 0,04468675 ! bile acid biosynthetic process GO:0006699 7 5 0,000 4,353E-03 0,04449977 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,353E-03 0,04431436 ! ganglioside catabolic process GO:0006689 12 5 0,000 4,353E-03 0,04413048 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,353E-03 0,04394812 ! decidualization GO:0046697 11 5 0,000 4,353E-03 0,04376727 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 4,353E-03 0,04358789 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 4,353E-03 0,04340998 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 4,353E-03 0,04323352 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 4,353E-03 0,04305849 ! embryonic cleavage GO:0040016 6 5 0,000 4,353E-03 0,04288486 ! peroxisome fission GO:0016559 5 5 0,000 4,353E-03 0,04271264 ! histone demethylation GO:0016577 13 5 0,000 4,353E-03 0,04254178 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 4,353E-03 0,0423723 ! mitotic recombination GO:0006312 9 5 0,000 4,353E-03 0,04220415 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 4,353E-03 0,04203734 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,353E-03 0,04187184 ! metaphase plate congression GO:0051310 7 5 0,000 4,353E-03 0,04170763 ! regulation of sterol transport GO:0032371 7 5 0,000 4,353E-03 0,04154471 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,353E-03 0,04138306 ! enteric nervous system development GO:0048484 8 5 0,000 4,353E-03 0,04122266 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 4,353E-03 0,0410635 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 4,353E-03 0,04090556 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 4,353E-03 0,04074884 ! muscle cell proliferation GO:0033002 12 5 0,000 4,353E-03 0,04059331 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,353E-03 0,04043896 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 4,353E-03 0,04028578 ! B cell homeostasis GO:0001782 13 5 0,000 4,353E-03 0,04013376 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 4,353E-03 0,03998288 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,353E-03 0,03983313 ! metaphase GO:0051323 11 5 0,000 4,353E-03 0,0396845 ! melatonin biosynthetic process GO:0030187 7 5 0,000 4,353E-03 0,03953697 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 4,353E-03 0,03939054 ! cellular response to nutrient GO:0031670 8 5 0,000 4,353E-03 0,03924519 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,353E-03 0,03910091 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 4,353E-03 0,03895768 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 4,353E-03 0,0388155 ! regulation of hair follicle development GO:0051797 10 5 0,000 4,353E-03 0,03867435 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 4,353E-03 0,03853423 ! response to redox state GO:0051775 6 5 0,000 4,353E-03 0,03839511 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 4,353E-03 0,038257 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 4,353E-03 0,03811988 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,353E-03 0,03798374 ! brown fat cell differentiation GO:0050873 7 5 0,000 4,353E-03 0,03784856 ! regulation of telomerase activity GO:0051972 7 5 0,000 4,353E-03 0,03771435 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,353E-03 0,03758108 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 4,353E-03 0,03744875 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,353E-03 0,03731735 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 4,353E-03 0,03718687 ! striatum development GO:0021756 14 5 0,000 4,353E-03 0,0370573 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 4,353E-03 0,03692863 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,353E-03 0,03680085 ! glial cell migration GO:0008347 10 5 0,000 4,353E-03 0,03667395 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,353E-03 0,03654792 ! neural plate morphogenesis GO:0001839 7 5 0,000 4,353E-03 0,03642276 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 4,353E-03 0,03629845 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,353E-03 0,03617499 ! T cell activation during immune response GO:0002286 9 5 0,000 4,353E-03 0,03605236 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,353E-03 0,03593056 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,353E-03 0,03580958 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 4,353E-03 0,03568942 ! neuroprotection GO:0043526 8 5 0,000 4,353E-03 0,03557005 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,353E-03 0,03545149 ! regulation of sensory perception GO:0051931 8 5 0,000 4,353E-03 0,03533371 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,353E-03 0,03521671 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,353E-03 0,03510048 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 4,353E-03 0,03498502 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 4,353E-03 0,03487032 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,353E-03 0,03475636 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 4,353E-03 0,03464315 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,353E-03 0,03453067 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 4,353E-03 0,03441892 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 4,353E-03 0,03430789 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 4,353E-03 0,03419758 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,353E-03 0,03408797 ! spindle assembly GO:0051225 6 5 0,000 4,353E-03 0,03397906 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,353E-03 0,03387085 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,353E-03 0,03376332 ! protein palmitoylation GO:0018345 12 5 0,000 4,353E-03 0,03365648 ! drug metabolic process GO:0017144 7 5 0,000 4,353E-03 0,0335503 ! stem cell division GO:0017145 11 5 0,000 4,353E-03 0,0334448 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,353E-03 0,03333996 ! organ regeneration GO:0031100 7 5 0,000 4,353E-03 0,03323577 ! carnitine metabolic process GO:0009437 8 5 0,000 4,353E-03 0,03313223 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,353E-03 0,03302934 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,222E-03 0,03949583 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,222E-03 0,03937393 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 5,222E-03 0,03925278 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 5,222E-03 0,03913237 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,222E-03 0,0390127 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 5,222E-03 0,03889376 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 5,222E-03 0,03877554 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,222E-03 0,03865804 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 5,222E-03 0,03854124 ! response to oxygen radical GO:0000305 11 6 0,000 5,222E-03 0,03842516 ! positive regulation of axon extension GO:0045773 13 6 0,000 5,222E-03 0,03830977 ! myoblast cell fate commitment GO:0048625 18 6 0,000 5,222E-03 0,03819507 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 5,222E-03 0,03808105 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 5,222E-03 0,03796771 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,222E-03 0,03785505 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,222E-03 0,03774305 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 5,222E-03 0,03763172 ! forebrain regionalization GO:0021871 9 6 0,000 5,222E-03 0,03752104 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,222E-03 0,037411 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,222E-03 0,03730161 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 5,222E-03 0,03719286 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,222E-03 0,03708474 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 5,222E-03 0,03697725 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 5,222E-03 0,03687038 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,222E-03 0,03676413 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 5,222E-03 0,03665848 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 5,222E-03 0,03655344 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,222E-03 0,03644901 ! malate metabolic process GO:0006108 13 6 0,000 5,222E-03 0,03634516 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 5,222E-03 0,03624191 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 5,222E-03 0,03613924 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 5,222E-03 0,03603715 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 5,222E-03 0,03593564 ! protein refolding GO:0042026 15 6 0,000 5,222E-03 0,0358347 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,222E-03 0,03573432 ! opsonization GO:0008228 8 6 0,000 5,222E-03 0,0356345 ! mating behavior GO:0007617 7 6 0,000 5,222E-03 0,03553524 ! erythrocyte maturation GO:0043249 8 6 0,000 5,222E-03 0,03543653 ! embryonic hemopoiesis GO:0035162 16 6 0,000 5,222E-03 0,03533837 ! protein amino acid dealkylation GO:0008214 15 6 0,000 5,222E-03 0,03524075 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 5,222E-03 0,03514367 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 5,222E-03 0,03504712 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,222E-03 0,0349511 ! response to interferon-gamma GO:0034341 16 6 0,000 5,222E-03 0,03485561 ! toxin metabolic process GO:0009404 11 6 0,000 5,222E-03 0,03476063 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,222E-03 0,03466617 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 5,222E-03 0,03457223 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 5,222E-03 0,03447879 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 5,222E-03 0,03438585 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 5,222E-03 0,03429342 ! cGMP-mediated signaling GO:0019934 14 6 0,000 5,222E-03 0,03420148 ! dorsal spinal cord development GO:0021516 10 6 0,000 5,222E-03 0,03411003 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,222E-03 0,03401907 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 5,222E-03 0,0339286 ! thymic T cell selection GO:0045061 16 6 0,000 5,222E-03 0,0338386 ! sphingoid catabolic process GO:0046521 8 6 0,000 5,222E-03 0,03374908 ! protein lipoylation GO:0009249 10 6 0,000 5,222E-03 0,03366003 ! transepithelial chloride transport GO:0030321 12 6 0,000 5,222E-03 0,03357145 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 5,222E-03 0,03348334 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,222E-03 0,03339569 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 5,222E-03 0,03330849 ! glutamate catabolic process GO:0006538 12 6 0,000 5,222E-03 0,03322175 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 5,222E-03 0,03313546 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,222E-03 0,03304962 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 5,222E-03 0,03296422 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,222E-03 0,03287926 ! hyperosmotic response GO:0006972 10 6 0,000 5,222E-03 0,03279474 ! L-serine biosynthetic process GO:0006564 7 6 0,000 5,222E-03 0,03271065 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 5,222E-03 0,03262699 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 5,222E-03 0,03254375 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,222E-03 0,03246095 ! urea metabolic process GO:0019627 7 6 0,000 5,222E-03 0,03237856 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,222E-03 0,03229659 ! neutrophil activation GO:0042119 7 6 0,000 5,222E-03 0,03221503 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,222E-03 0,03213388 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 5,222E-03 0,03205315 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,222E-03 0,03197281 ! paraxial mesoderm development GO:0048339 16 6 0,000 5,222E-03 0,03189288 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 5,222E-03 0,03181335 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,222E-03 0,03173421 ! neuron apoptosis GO:0051402 15 6 0,000 5,222E-03 0,03165546 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,222E-03 0,03157711 ! T cell mediated immunity GO:0002456 17 6 0,000 5,222E-03 0,03149914 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,222E-03 0,03142156 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 5,222E-03 0,03134435 ! carnitine transport GO:0015879 10 6 0,000 5,222E-03 0,03126753 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,222E-03 0,03119108 ! positive regulation of exocytosis GO:0045921 11 6 0,000 5,222E-03 0,031115 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 5,222E-03 0,0310393 ! early endosome to late endosome transport GO:0045022 16 6 0,000 5,222E-03 0,03096396 ! 5S class rRNA transcription GO:0042791 13 6 0,000 5,222E-03 0,03088899 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,222E-03 0,03081438 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 5,222E-03 0,03074013 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 5,222E-03 0,03066623 ! sodium ion homeostasis GO:0055078 12 6 0,000 5,222E-03 0,03059269 ! establishment of spindle localization GO:0051293 16 6 0,000 5,222E-03 0,0305195 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 5,222E-03 0,03044666 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,222E-03 0,03037417 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 5,222E-03 0,03030202 ! response to UV-C GO:0010225 14 6 0,000 5,222E-03 0,03023022 ! astrocyte development GO:0014002 16 6 0,000 5,222E-03 0,03015875 ! protein targeting to lysosome GO:0006622 12 6 0,000 5,222E-03 0,03008762 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,222E-03 0,03001683 ! interaction with symbiont GO:0051702 14 6 0,000 5,222E-03 0,02994637 ! regulation of dendrite development GO:0050773 16 6 0,000 5,222E-03 0,02987623 ! peptidyl-arginine modification GO:0018195 13 6 0,000 5,222E-03 0,02980643 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 5,222E-03 0,02973695 ! response to copper ion GO:0046688 10 6 0,000 5,222E-03 0,0296678 ! response to exogenous dsRNA GO:0043330 13 6 0,000 5,222E-03 0,02959896 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 5,222E-03 0,02953044 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,222E-03 0,02946224 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 5,222E-03 0,02939436 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,222E-03 0,02932679 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 5,222E-03 0,02925952 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,222E-03 0,02919257 ! nucleoside catabolic process GO:0009164 10 6 0,000 5,222E-03 0,02912592 ! hair follicle maturation GO:0048820 8 6 0,000 5,222E-03 0,02905957 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,222E-03 0,02899353 ! Schwann cell development GO:0014044 15 6 0,000 5,222E-03 0,02892778 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 5,222E-03 0,02886233 ! response to pheromone GO:0019236 6 6 0,000 5,222E-03 0,02879718 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 5,222E-03 0,02873232 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 5,222E-03 0,02866776 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 5,222E-03 0,02860348 ! base conversion or substitution editing GO:0016553 6 6 0,000 5,222E-03 0,02853949 ! subpallium development GO:0021544 15 6 0,000 5,222E-03 0,02847579 ! neural tube patterning GO:0021532 8 6 0,000 5,222E-03 0,02841237 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 5,222E-03 0,02834923 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 5,222E-03 0,02828637 ! maintenance of organ identity GO:0048496 9 6 0,000 5,222E-03 0,02822379 ! G2 phase GO:0051319 16 6 0,000 5,222E-03 0,02816148 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 5,222E-03 0,02809945 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 5,222E-03 0,0280377 ! oxygen homeostasis GO:0032364 10 6 0,000 5,222E-03 0,02797621 ! establishment of planar polarity GO:0001736 7 6 0,000 5,222E-03 0,02791499 ! regulation of mast cell activation GO:0033003 13 6 0,000 5,222E-03 0,02785404 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,222E-03 0,02779336 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 5,222E-03 0,02773294 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,222E-03 0,02767278 ! receptor internalization GO:0031623 11 6 0,000 5,222E-03 0,02761288 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 5,222E-03 0,02755324 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 5,222E-03 0,02749386 ! neutrophil homeostasis GO:0001780 11 6 0,000 5,222E-03 0,02743474 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,222E-03 0,02737586 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 5,222E-03 0,02731724 ! protein deubiquitination GO:0016579 16 6 0,000 5,222E-03 0,02725887 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 5,222E-03 0,02720075 ! protein destabilization GO:0031648 9 6 0,000 5,222E-03 0,02714288 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 5,222E-03 0,02708525 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,222E-03 0,02702786 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 5,222E-03 0,02697072 ! regulation of viral transcription GO:0046782 11 6 0,000 5,222E-03 0,02691382 ! progesterone metabolic process GO:0042448 12 6 0,000 5,222E-03 0,02685716 ! negative regulation of axon extension GO:0030517 24 6 0,000 5,222E-03 0,02680074 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 5,222E-03 0,02674455 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 5,222E-03 0,0266886 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,222E-03 0,02663289 ! determination of adult lifespan GO:0008340 17 6 0,000 5,222E-03 0,0265774 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 5,222E-03 0,02652215 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 5,222E-03 0,02646712 ! neural plate development GO:0001840 9 6 0,000 5,222E-03 0,02641232 ! catecholamine transport GO:0051937 9 6 0,000 5,222E-03 0,02635775 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 5,222E-03 0,02630341 ! sensory cilium assembly GO:0035058 10 6 0,000 5,222E-03 0,02624928 ! organ or tissue specific immune response GO:0002251 8 6 0,000 5,222E-03 0,02619538 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 5,222E-03 0,0261417 ! maternal placenta development GO:0001893 12 6 0,000 5,222E-03 0,02608825 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 5,222E-03 0,026035 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,222E-03 0,02598198 ! negative regulation of B cell activation GO:0050869 14 6 0,000 5,222E-03 0,02592917 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 5,222E-03 0,02587658 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 5,222E-03 0,02582419 ! positive regulation of coagulation GO:0050820 13 6 0,000 5,222E-03 0,02577202 ! cellular anion homeostasis GO:0030002 11 6 0,000 5,222E-03 0,02572006 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 6,09E-03 0,02993374 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 6,09E-03 0,02987363 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 6,09E-03 0,02981376 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,09E-03 0,02975413 ! regulation of helicase activity GO:0051095 16 7 0,000 6,09E-03 0,02969474 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 6,09E-03 0,02963559 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 6,09E-03 0,02957667 ! sleep GO:0030431 16 7 0,000 6,09E-03 0,02951799 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,09E-03 0,02945954 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 6,09E-03 0,02940132 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,09E-03 0,02934333 ! prostate gland development GO:0030850 14 7 0,000 6,09E-03 0,02928556 ! nucleotide-sugar transport GO:0015780 11 7 0,000 6,09E-03 0,02922803 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,09E-03 0,02917072 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,09E-03 0,02911363 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 6,09E-03 0,02905677 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,09E-03 0,02900013 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 6,09E-03 0,02894371 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 6,09E-03 0,02888751 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,09E-03 0,02883152 ! SMAD protein complex assembly GO:0007183 13 7 0,000 6,09E-03 0,02877576 ! glycolipid transport GO:0046836 11 7 0,000 6,09E-03 0,02872021 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,09E-03 0,02866487 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,09E-03 0,02860974 ! neuron adhesion GO:0007158 14 7 0,000 6,09E-03 0,02855483 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 6,09E-03 0,02850013 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,09E-03 0,02844563 ! establishment of tissue polarity GO:0007164 8 7 0,000 6,09E-03 0,02839135 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 6,09E-03 0,02833727 ! mRNA stabilization GO:0048255 18 7 0,000 6,09E-03 0,0282834 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 6,09E-03 0,02822973 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 6,09E-03 0,02817626 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 6,09E-03 0,028123 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 6,09E-03 0,02806994 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 6,09E-03 0,02801707 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,09E-03 0,02796441 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,09E-03 0,02791194 ! lipoprotein transport GO:0042953 14 7 0,000 6,09E-03 0,02785968 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 6,09E-03 0,0278076 ! rhythmic behavior GO:0007622 17 7 0,000 6,09E-03 0,02775572 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 6,09E-03 0,02770403 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 6,09E-03 0,02765254 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 6,09E-03 0,02760124 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 6,09E-03 0,02755012 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,09E-03 0,0274992 ! regulation of odontogenesis GO:0042481 14 7 0,000 6,09E-03 0,02744846 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,09E-03 0,02739791 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 6,09E-03 0,02734755 ! mechanosensory behavior GO:0007638 16 7 0,000 6,09E-03 0,02729737 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 6,09E-03 0,02724737 ! positive regulation of isotype switching GO:0045830 17 7 0,000 6,09E-03 0,02719756 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 6,09E-03 0,02714793 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 6,09E-03 0,02709848 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,09E-03 0,02704921 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,09E-03 0,02700012 ! spinal cord patterning GO:0021511 14 7 0,000 6,09E-03 0,02695121 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 6,09E-03 0,02690247 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 6,09E-03 0,02685391 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,09E-03 0,02680553 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 6,09E-03 0,02675731 ! adrenal gland development GO:0030325 17 7 0,000 6,09E-03 0,02670928 ! cysteine metabolic process GO:0006534 13 7 0,000 6,09E-03 0,02666141 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 6,09E-03 0,02661371 ! ovulation GO:0030728 10 7 0,000 6,09E-03 0,02656619 ! adenohypophysis development GO:0021984 11 7 0,000 6,09E-03 0,02651884 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 6,09E-03 0,02647165 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 6,09E-03 0,02642463 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 6,09E-03 0,02637778 ! microtubule nucleation GO:0007020 21 7 0,000 6,09E-03 0,02633109 ! proline biosynthetic process GO:0006561 10 7 0,000 6,09E-03 0,02628457 ! tryptophan metabolic process GO:0006568 11 7 0,000 6,09E-03 0,02623821 ! thyroid hormone generation GO:0006590 13 7 0,000 6,09E-03 0,02619202 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 6,09E-03 0,02614599 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 6,09E-03 0,02610012 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,09E-03 0,02605441 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 6,09E-03 0,02600886 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 6,09E-03 0,02596347 ! galactose metabolic process GO:0006012 13 7 0,000 6,09E-03 0,02591823 ! vesicle fusion GO:0006906 20 7 0,000 6,09E-03 0,02587316 ! response to dietary excess GO:0002021 8 7 0,000 6,09E-03 0,02582824 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,09E-03 0,02578348 ! intracellular pH reduction GO:0051452 13 7 0,000 6,09E-03 0,02573887 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,09E-03 0,02569442 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 6,09E-03 0,02565011 ! organ growth GO:0035265 15 7 0,000 6,09E-03 0,02560597 ! nucleoside transport GO:0015858 11 7 0,000 6,09E-03 0,02556197 ! nucleoside salvage GO:0043174 11 7 0,000 6,09E-03 0,02551812 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 6,09E-03 0,02547443 ! male sex determination GO:0030238 15 7 0,000 6,09E-03 0,02543088 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 6,09E-03 0,02538749 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 6,09E-03 0,02534424 ! parturition GO:0007567 16 7 0,000 6,09E-03 0,02530113 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 6,09E-03 0,02525818 ! rRNA modification GO:0000154 14 7 0,000 6,09E-03 0,02521537 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 6,09E-03 0,0251727 ! spindle checkpoint GO:0031577 16 7 0,000 6,09E-03 0,02513018 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 6,09E-03 0,0250878 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 6,09E-03 0,02504557 ! monocyte differentiation GO:0030224 16 7 0,000 6,09E-03 0,02500347 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 6,09E-03 0,02496152 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,09E-03 0,02491971 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 6,09E-03 0,02487804 ! hyaluronan metabolic process GO:0030212 9 7 0,000 6,09E-03 0,02483651 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 6,09E-03 0,02479511 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,09E-03 0,02475385 ! fibrinolysis GO:0042730 11 7 0,000 6,09E-03 0,02471274 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 6,09E-03 0,02467175 ! skeletal muscle contraction GO:0003009 8 7 0,000 6,09E-03 0,0246309 ! eating behavior GO:0042755 8 7 0,000 6,09E-03 0,02459019 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,09E-03 0,02454961 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 6,09E-03 0,02450917 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 6,09E-03 0,02446886 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,09E-03 0,02442868 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 6,09E-03 0,02438863 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,09E-03 0,02434872 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 6,09E-03 0,02430893 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 6,09E-03 0,02426928 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 6,09E-03 0,02422975 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 6,09E-03 0,02419035 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,09E-03 0,02415108 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 6,09E-03 0,02411194 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,09E-03 0,02407292 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,09E-03 0,02403403 ! histone ubiquitination GO:0016574 9 7 0,000 6,09E-03 0,02399527 ! regulation of meiosis GO:0040020 12 7 0,000 6,09E-03 0,02395663 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 6,09E-03 0,02391811 ! T cell lineage commitment GO:0002360 16 7 0,000 6,09E-03 0,02387972 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 6,09E-03 0,02384145 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,09E-03 0,02380331 ! membrane to membrane docking GO:0022614 14 7 0,000 6,09E-03 0,02376528 ! transcription termination GO:0006353 14 7 0,000 6,09E-03 0,02372738 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,09E-03 0,0236896 ! anaphase GO:0051322 18 7 0,000 6,09E-03 0,02365193 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 6,09E-03 0,02361439 ! axonal fasciculation GO:0007413 19 7 0,000 6,09E-03 0,02357697 ! negative regulation of nuclear division GO:0051784 15 7 0,000 6,09E-03 0,02353966 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 6,09E-03 0,02350247 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 6,09E-03 0,0234654 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 6,09E-03 0,02342845 ! diuresis GO:0030146 12 7 0,000 6,09E-03 0,02339161 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,09E-03 0,02335489 ! thiamin metabolic process GO:0006772 7 7 0,000 6,09E-03 0,02331829 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,09E-03 0,02328179 ! antibiotic transport GO:0042891 9 7 0,000 6,09E-03 0,02324542 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,09E-03 0,02320915 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 6,09E-03 0,023173 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 6,09E-03 0,02313696 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 6,09E-03 0,02310104 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 6,09E-03 0,02306522 ! melanin biosynthetic process GO:0042438 10 7 0,000 6,09E-03 0,02302951 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 6,09E-03 0,02299392 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,09E-03 0,02295844 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,09E-03 0,02292306 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 6,09E-03 0,02288779 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 6,09E-03 0,02285264 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 6,09E-03 0,02281759 ! endosome to lysosome transport GO:0008333 12 7 0,000 6,09E-03 0,02278264 ! protein modification by small protein removal GO:0070646 19 7 0,000 6,09E-03 0,02274781 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 6,09E-03 0,02271308 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 6,09E-03 0,02267846 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 6,09E-03 0,02264394 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 6,09E-03 0,02260952 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,09E-03 0,02257521 ! muscle adaptation GO:0043500 13 7 0,000 6,09E-03 0,02254101 ! embryonic heart tube development GO:0035050 14 7 0,000 6,09E-03 0,02250691 ! retina homeostasis GO:0001895 12 7 0,000 6,09E-03 0,02247291 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 6,09E-03 0,02243901 ! protein amino acid prenylation GO:0018346 19 7 0,000 6,09E-03 0,02240522 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 6,09E-03 0,02237153 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 6,09E-03 0,02233794 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 6,957E-03 0,02548005 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 6,957E-03 0,0254419 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 6,957E-03 0,02540387 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 6,957E-03 0,02536596 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 6,957E-03 0,02532815 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,957E-03 0,02529046 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,957E-03 0,02525289 ! male meiosis GO:0007140 9 8 0,000 6,957E-03 0,02521542 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 6,957E-03 0,02517806 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 6,957E-03 0,02514082 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 6,957E-03 0,02510368 ! meiotic prophase I GO:0007128 14 8 0,000 6,957E-03 0,02506665 ! response to zinc ion GO:0010043 12 8 0,000 6,957E-03 0,02502974 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 6,957E-03 0,02499293 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,957E-03 0,02495623 ! oligopeptide transport GO:0006857 16 8 0,000 6,957E-03 0,02491964 ! actin-myosin filament sliding GO:0033275 13 8 0,000 6,957E-03 0,02488315 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 6,957E-03 0,02484677 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 6,957E-03 0,0248105 ! signal peptide processing GO:0006465 12 8 0,000 6,957E-03 0,02477433 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 6,957E-03 0,02473827 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 6,957E-03 0,02470231 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,957E-03 0,02466646 ! succinate metabolic process GO:0006105 17 8 0,000 6,957E-03 0,02463071 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 6,957E-03 0,02459507 ! membrane hyperpolarization GO:0060081 11 8 0,000 6,957E-03 0,02455953 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,957E-03 0,02452409 ! estrogen metabolic process GO:0008210 17 8 0,000 6,957E-03 0,02448875 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 6,957E-03 0,02445351 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,957E-03 0,02441838 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 6,957E-03 0,02438335 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,957E-03 0,02434841 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,957E-03 0,02431358 ! reflex GO:0060004 17 8 0,000 6,957E-03 0,02427885 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,957E-03 0,02424421 ! glycerolipid catabolic process GO:0046503 14 8 0,000 6,957E-03 0,02420967 ! hemoglobin metabolic process GO:0020027 14 8 0,000 6,957E-03 0,02417524 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,957E-03 0,0241409 ! pigment granule organization GO:0048753 17 8 0,000 6,957E-03 0,02410665 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,957E-03 0,02407251 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 6,957E-03 0,02403846 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 6,957E-03 0,02400451 ! astrocyte differentiation GO:0048708 19 8 0,000 6,957E-03 0,02397065 ! histidine catabolic process GO:0006548 10 8 0,000 6,957E-03 0,02393689 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,957E-03 0,02390322 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 6,957E-03 0,02386965 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 6,957E-03 0,02383617 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 6,957E-03 0,02380279 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 6,957E-03 0,0237695 ! regulation of pigmentation during development GO:0048070 25 8 0,000 6,957E-03 0,0237363 ! melanin metabolic process GO:0006582 17 8 0,000 6,957E-03 0,0237032 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 6,957E-03 0,02367018 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 6,957E-03 0,02363726 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 6,957E-03 0,02360443 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,957E-03 0,02357169 ! macrophage activation GO:0042116 13 8 0,000 6,957E-03 0,02353905 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,957E-03 0,02350649 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,957E-03 0,02347402 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 6,957E-03 0,02344164 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,957E-03 0,02340935 ! purine salvage GO:0043101 12 8 0,000 6,957E-03 0,02337716 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 6,957E-03 0,02334504 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,957E-03 0,02331302 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 6,957E-03 0,02328108 ! osteoblast development GO:0002076 17 8 0,000 6,957E-03 0,02324924 ! positive regulation of vasodilation GO:0045909 14 8 0,000 6,957E-03 0,02321747 ! negative regulation of translational initiation GO:0045947 12 8 0,000 6,957E-03 0,0231858 ! Schwann cell differentiation GO:0014037 21 8 0,000 6,957E-03 0,02315421 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 6,957E-03 0,02312271 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,957E-03 0,02309129 ! response to UV-B GO:0010224 17 8 0,000 6,957E-03 0,02305996 ! protein targeting to vacuole GO:0006623 14 8 0,000 6,957E-03 0,02302872 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,957E-03 0,02299755 ! intermediate filament organization GO:0045109 12 8 0,000 6,957E-03 0,02296648 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 6,957E-03 0,02293548 ! cellular extravasation GO:0045123 13 8 0,000 6,957E-03 0,02290457 ! cardiac muscle cell development GO:0055013 14 8 0,000 6,957E-03 0,02287374 ! response to antibiotic GO:0046677 11 8 0,000 6,957E-03 0,022843 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 6,957E-03 0,02281234 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 6,957E-03 0,02278176 ! DNA topological change GO:0006265 12 8 0,000 6,957E-03 0,02275126 ! response to tropane GO:0014073 15 8 0,000 6,957E-03 0,02272084 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 6,957E-03 0,02269051 ! melanosome transport GO:0032402 13 8 0,000 6,957E-03 0,02266026 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 6,957E-03 0,02263008 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 6,957E-03 0,02259999 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,957E-03 0,02256998 ! mast cell activation GO:0045576 14 8 0,000 6,957E-03 0,02254004 ! multicellular organismal aging GO:0010259 20 8 0,000 6,957E-03 0,02251019 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 6,957E-03 0,02248041 ! gas homeostasis GO:0033483 14 8 0,000 6,957E-03 0,02245072 ! dendrite morphogenesis GO:0048813 14 8 0,000 6,957E-03 0,0224211 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 6,957E-03 0,02239156 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 6,957E-03 0,02236209 ! nucleosome disassembly GO:0006337 14 8 0,000 6,957E-03 0,02233271 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,957E-03 0,0223034 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 6,957E-03 0,02227417 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,957E-03 0,02224502 ! establishment of chromosome localization GO:0051303 14 8 0,000 6,957E-03 0,02221594 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 6,957E-03 0,02218693 ! intracellular lipid transport GO:0032365 16 8 0,000 6,957E-03 0,02215801 ! response to tumor cell GO:0002347 16 8 0,000 6,957E-03 0,02212916 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,957E-03 0,02210038 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 6,957E-03 0,02207168 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 6,957E-03 0,02204305 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 6,957E-03 0,0220145 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,957E-03 0,02198602 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 6,957E-03 0,02195761 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 6,957E-03 0,02192928 ! hormone catabolic process GO:0042447 17 8 0,000 6,957E-03 0,02190102 ! glycolipid catabolic process GO:0019377 16 8 0,000 6,957E-03 0,02187283 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 6,957E-03 0,02184472 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 6,957E-03 0,02181668 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 6,957E-03 0,02178871 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,957E-03 0,02176081 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 6,957E-03 0,02173298 ! adult feeding behavior GO:0008343 10 8 0,000 6,957E-03 0,02170523 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 6,957E-03 0,02167754 ! ATP catabolic process GO:0006200 11 8 0,000 6,957E-03 0,02164993 ! blastocyst growth GO:0001832 19 8 0,000 6,957E-03 0,02162238 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,957E-03 0,02159491 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,957E-03 0,0215675 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 6,957E-03 0,02154017 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,957E-03 0,0215129 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 6,957E-03 0,0214857 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 6,957E-03 0,02145858 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 6,957E-03 0,02143152 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 6,957E-03 0,02140452 ! amino sugar catabolic process GO:0046348 11 8 0,000 6,957E-03 0,0213776 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 6,957E-03 0,02135074 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,957E-03 0,02132395 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 6,957E-03 0,02129723 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 6,957E-03 0,02127058 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,957E-03 0,02124399 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 6,957E-03 0,02121747 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 6,957E-03 0,02119101 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,957E-03 0,02116462 ! NAD biosynthetic process GO:0009435 17 8 0,000 6,957E-03 0,0211383 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 6,957E-03 0,02111204 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 6,957E-03 0,02108585 ! axon extension GO:0048675 16 9 0,000 7,823E-03 0,02368219 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,823E-03 0,02365288 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 7,823E-03 0,02362364 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 7,823E-03 0,02359448 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,823E-03 0,02356539 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 7,823E-03 0,02353637 ! cell proliferation in forebrain GO:0021846 18 9 0,000 7,823E-03 0,02350742 ! neutral lipid catabolic process GO:0046461 14 9 0,000 7,823E-03 0,02347854 ! reproductive behavior GO:0019098 22 9 0,000 7,823E-03 0,02344973 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,823E-03 0,02342099 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 7,823E-03 0,02339232 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 7,823E-03 0,02336373 ! UTP metabolic process GO:0046051 10 9 0,000 7,823E-03 0,0233352 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 7,823E-03 0,02330674 ! induction of positive chemotaxis GO:0050930 17 9 0,000 7,823E-03 0,02327835 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 7,823E-03 0,02325003 ! artery development GO:0060840 25 9 0,000 7,823E-03 0,02322178 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 7,823E-03 0,0231936 ! regulation of glycolysis GO:0006110 20 9 0,000 7,823E-03 0,02316549 ! cerebral cortex cell migration GO:0021795 18 9 0,000 7,823E-03 0,02313744 ! equilibrioception GO:0050957 20 9 0,000 7,823E-03 0,02310947 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 7,823E-03 0,02308156 ! chemosensory behavior GO:0007635 21 9 0,000 7,823E-03 0,02305371 ! microtubule bundle formation GO:0001578 22 9 0,000 7,823E-03 0,02302594 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,823E-03 0,02299823 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 7,823E-03 0,02297059 ! leukocyte degranulation GO:0043299 16 9 0,000 7,823E-03 0,02294301 ! ganglioside metabolic process GO:0001573 22 9 0,000 7,823E-03 0,0229155 ! negative regulation of endocytosis GO:0045806 12 9 0,000 7,823E-03 0,02288806 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 7,823E-03 0,02286068 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 7,823E-03 0,02283337 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,823E-03 0,02280612 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,823E-03 0,02277894 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 7,823E-03 0,02275182 ! protein targeting to ER GO:0045047 25 9 0,000 7,823E-03 0,02272477 ! ceramide biosynthetic process GO:0046513 20 9 0,000 7,823E-03 0,02269778 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 7,823E-03 0,02267085 ! T cell selection GO:0045058 27 9 0,000 7,823E-03 0,02264399 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 7,823E-03 0,02261719 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 7,823E-03 0,02259046 ! glycine catabolic process GO:0006546 15 9 0,000 7,823E-03 0,02256379 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 7,823E-03 0,02253718 ! endosome organization GO:0007032 20 9 0,000 7,823E-03 0,02251063 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 7,823E-03 0,02248415 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 7,823E-03 0,02245773 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,823E-03 0,02243137 ! mannose metabolic process GO:0006013 13 9 0,000 7,823E-03 0,02240507 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 7,823E-03 0,02237884 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 7,823E-03 0,02235267 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 7,823E-03 0,02232655 ! Rac protein signal transduction GO:0016601 20 9 0,000 7,823E-03 0,0223005 ! receptor clustering GO:0043113 20 9 0,000 7,823E-03 0,02227451 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 7,823E-03 0,02224858 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,823E-03 0,02222271 ! retinol metabolic process GO:0042572 20 9 0,000 7,823E-03 0,0221969 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 7,823E-03 0,02217115 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 7,823E-03 0,02214546 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 7,823E-03 0,02211982 ! macrophage differentiation GO:0030225 15 9 0,000 7,823E-03 0,02209425 ! oligodendrocyte development GO:0014003 11 9 0,000 7,823E-03 0,02206874 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 7,823E-03 0,02204329 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,823E-03 0,02201789 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 7,823E-03 0,02199255 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,823E-03 0,02196727 ! response to amine stimulus GO:0014075 13 9 0,000 7,823E-03 0,02194205 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,823E-03 0,02191689 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 7,823E-03 0,02189179 ! erythrocyte development GO:0048821 17 9 0,000 7,823E-03 0,02186674 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,823E-03 0,02184175 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 7,823E-03 0,02181681 ! renal water homeostasis GO:0003091 15 9 0,000 7,823E-03 0,02179194 ! postreplication repair GO:0006301 25 9 0,000 7,823E-03 0,02176712 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 7,823E-03 0,02174235 ! icosanoid secretion GO:0032309 15 9 0,000 7,823E-03 0,02171765 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,823E-03 0,021693 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 7,823E-03 0,0216684 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 7,823E-03 0,02164386 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 7,823E-03 0,02161938 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,823E-03 0,02159495 ! sterol catabolic process GO:0016127 14 9 0,000 7,823E-03 0,02157057 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,823E-03 0,02154626 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 7,823E-03 0,02152199 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 7,823E-03 0,02149778 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 7,823E-03 0,02147363 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 7,823E-03 0,02144953 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 7,823E-03 0,02142548 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 7,823E-03 0,02140149 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 7,823E-03 0,02137755 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 7,823E-03 0,02135366 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 7,823E-03 0,02132983 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,823E-03 0,02130605 ! purine base metabolic process GO:0006144 25 9 0,000 7,823E-03 0,02128233 ! pigment granule transport GO:0051904 17 9 0,000 7,823E-03 0,02125865 ! regulation of telomere maintenance GO:0032204 17 9 0,000 7,823E-03 0,02123503 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 7,823E-03 0,02121146 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 7,823E-03 0,02118795 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,823E-03 0,02116448 ! regulation of amino acid transport GO:0051955 12 9 0,000 7,823E-03 0,02114107 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 7,823E-03 0,02111771 ! mitochondrion localization GO:0051646 18 9 0,000 7,823E-03 0,0210944 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 8,689E-03 0,02340251 ! regulation of developmental growth GO:0048638 16 10 0,000 8,689E-03 0,02337674 ! autophagic vacuole formation GO:0000045 17 10 0,000 8,689E-03 0,02335102 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,689E-03 0,02332536 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 8,689E-03 0,02329976 ! associative learning GO:0008306 21 10 0,000 8,689E-03 0,02327421 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,689E-03 0,02324872 ! phosphate transport GO:0006817 24 10 0,000 8,689E-03 0,02322328 ! cell volume homeostasis GO:0006884 17 10 0,000 8,689E-03 0,0231979 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 8,689E-03 0,02317258 ! CTP metabolic process GO:0046036 11 10 0,000 8,689E-03 0,02314731 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 8,689E-03 0,02312209 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,689E-03 0,02309693 ! GTP metabolic process GO:0046039 11 10 0,000 8,689E-03 0,02307182 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 8,689E-03 0,02304677 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 8,689E-03 0,02302178 ! social behavior GO:0035176 29 10 0,000 8,689E-03 0,02299684 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 8,689E-03 0,02297195 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 8,689E-03 0,02294711 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 8,689E-03 0,02292233 ! androgen metabolic process GO:0008209 17 10 0,000 8,689E-03 0,0228976 ! phospholipid efflux GO:0033700 19 10 0,000 8,689E-03 0,02287293 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,689E-03 0,02284831 ! bile acid and bile salt transport GO:0015721 15 10 0,000 8,689E-03 0,02282374 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 8,689E-03 0,02279923 ! positive regulation of heart contraction GO:0045823 17 10 0,000 8,689E-03 0,02277476 ! lung alveolus development GO:0048286 26 10 0,000 8,689E-03 0,02275035 ! pathogenesis GO:0009405 17 10 0,000 8,689E-03 0,02272599 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,689E-03 0,02270169 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 8,689E-03 0,02267743 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 8,689E-03 0,02265323 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 8,689E-03 0,02262908 ! endoderm development GO:0007492 18 10 0,000 8,689E-03 0,02260498 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 8,689E-03 0,02258093 ! arginine catabolic process GO:0006527 17 10 0,000 8,689E-03 0,02255694 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,689E-03 0,02253299 ! proline metabolic process GO:0006560 13 10 0,000 8,689E-03 0,0225091 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,689E-03 0,02248525 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 8,689E-03 0,02246146 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 8,689E-03 0,02243772 ! V(D)J recombination GO:0033151 34 10 0,000 8,689E-03 0,02241402 ! reverse cholesterol transport GO:0043691 19 10 0,000 8,689E-03 0,02239038 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 8,689E-03 0,02236678 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 8,689E-03 0,02234324 ! B cell proliferation GO:0042100 19 10 0,000 8,689E-03 0,02231975 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 8,689E-03 0,0222963 ! regulation of sodium ion transport GO:0002028 26 10 0,000 8,689E-03 0,02227291 ! multicellular organism growth GO:0035264 19 10 0,000 8,689E-03 0,02224956 ! phagocytosis, engulfment GO:0006911 33 10 0,000 8,689E-03 0,02222626 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 8,689E-03 0,02220301 ! ruffle organization GO:0031529 17 10 0,000 8,689E-03 0,02217981 ! epithelial cell development GO:0002064 21 10 0,000 8,689E-03 0,02215666 ! lens development in camera-type eye GO:0002088 17 10 0,000 8,689E-03 0,02213355 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,689E-03 0,0221105 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 8,689E-03 0,02208749 ! positive regulation of translational initiation GO:0045948 12 10 0,000 8,689E-03 0,02206453 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 8,689E-03 0,02204162 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 8,689E-03 0,02201875 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 8,689E-03 0,02199594 ! motor axon guidance GO:0008045 22 10 0,000 8,689E-03 0,02197317 ! copper ion homeostasis GO:0055070 13 10 0,000 8,689E-03 0,02195044 ! regulation of bone resorption GO:0045124 25 10 0,000 8,689E-03 0,02192777 ! protein heterooligomerization GO:0051291 17 10 0,000 8,689E-03 0,02190514 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,689E-03 0,02188256 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,689E-03 0,02186002 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 8,689E-03 0,02183753 ! segment specification GO:0007379 15 10 0,000 8,689E-03 0,02181509 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 8,689E-03 0,02179269 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 8,689E-03 0,02177034 ! blastoderm segmentation GO:0007350 19 10 0,000 8,689E-03 0,02174803 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 8,689E-03 0,02172577 ! response to dsRNA GO:0043331 23 10 0,000 8,689E-03 0,02170356 ! DNA ligation GO:0006266 18 10 0,000 8,689E-03 0,02168139 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 8,689E-03 0,02165926 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,689E-03 0,02163719 ! melanosome localization GO:0032400 16 10 0,000 8,689E-03 0,02161515 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 8,689E-03 0,02159316 ! regulation of B cell differentiation GO:0045577 24 10 0,000 8,689E-03 0,02157122 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 8,689E-03 0,02154932 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,689E-03 0,02152746 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 8,689E-03 0,02150565 ! induction of an organ GO:0001759 17 10 0,000 8,689E-03 0,02148389 ! leukocyte activation during immune response GO:0002366 15 10 0,000 8,689E-03 0,02146216 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 8,689E-03 0,02144048 ! protein sumoylation GO:0016925 17 10 0,000 8,689E-03 0,02141885 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 8,689E-03 0,02139726 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,689E-03 0,02137571 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,689E-03 0,0213542 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,689E-03 0,02133274 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 8,689E-03 0,02131132 ! salivary gland development GO:0007431 28 10 0,000 8,689E-03 0,02128995 ! ubiquinone metabolic process GO:0006743 17 10 0,000 8,689E-03 0,02126862 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 8,689E-03 0,02124733 ! midbrain development GO:0030901 14 10 0,000 8,689E-03 0,02122608 ! musculoskeletal movement GO:0050881 16 10 0,000 8,689E-03 0,02120487 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 8,689E-03 0,02118371 ! methionine biosynthetic process GO:0009086 21 10 0,000 8,689E-03 0,02116259 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 8,689E-03 0,02114151 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 8,689E-03 0,02112048 ! quaternary ammonium group transport GO:0015697 22 10 0,000 8,689E-03 0,02109948 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,689E-03 0,02107853 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,689E-03 0,02105762 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 8,689E-03 0,02103675 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 8,689E-03 0,02101592 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 8,689E-03 0,02099513 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,689E-03 0,02097439 ! blastocyst formation GO:0001825 18 10 0,000 8,689E-03 0,02095368 ! regulation of fibrinolysis GO:0051917 20 10 0,000 8,689E-03 0,02093302 ! cerebellar cortex development GO:0021695 16 10 0,000 8,689E-03 0,02091239 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 8,689E-03 0,02089181 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 8,689E-03 0,02087127 ! response to nicotine GO:0035094 20 10 0,000 8,689E-03 0,02085077 ! negative regulation of immune effector process GO:0002698 23 10 0,000 8,689E-03 0,0208303 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,689E-03 0,02080988 ! negative regulation of muscle development GO:0048635 27 11 0,000 9,553E-03 0,02285881 ! respiratory burst GO:0045730 17 11 0,000 9,553E-03 0,02283644 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 9,553E-03 0,02281412 ! neuron fate specification GO:0048665 18 11 0,000 9,553E-03 0,02279184 ! telencephalon cell migration GO:0022029 23 11 0,000 9,553E-03 0,0227696 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 9,553E-03 0,02274741 ! thyroid gland development GO:0030878 26 11 0,000 9,553E-03 0,02272526 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 9,553E-03 0,02270316 ! synapsis GO:0007129 14 11 0,000 9,553E-03 0,02268109 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 9,553E-03 0,02265907 ! Golgi vesicle budding GO:0048194 26 11 0,000 9,553E-03 0,02263709 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 9,553E-03 0,02261516 ! response to pain GO:0048265 27 11 0,000 9,553E-03 0,02259327 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,553E-03 0,02257142 ! keratinocyte proliferation GO:0043616 19 11 0,000 9,553E-03 0,02254961 ! blood vessel remodeling GO:0001974 30 11 0,000 9,553E-03 0,02252784 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 9,553E-03 0,02250612 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 9,553E-03 0,02248444 ! bone resorption GO:0045453 16 11 0,000 9,553E-03 0,02246279 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 9,553E-03 0,0224412 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 9,553E-03 0,02241964 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,553E-03 0,02239812 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,553E-03 0,02237665 ! melanocyte differentiation GO:0030318 20 11 0,000 9,553E-03 0,02235521 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 9,553E-03 0,02233382 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 9,553E-03 0,02231247 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 9,553E-03 0,02229116 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 9,553E-03 0,02226989 ! regulation of intracellular pH GO:0051453 21 11 0,000 9,553E-03 0,02224866 ! substrate-bound cell migration GO:0006929 14 11 0,000 9,553E-03 0,02222747 ! UV protection GO:0009650 20 11 0,000 9,553E-03 0,02220632 ! adult heart development GO:0007512 16 11 0,000 9,553E-03 0,02218521 ! chondrocyte differentiation GO:0002062 27 11 0,000 9,553E-03 0,02216414 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,553E-03 0,02214312 ! macroautophagy GO:0016236 19 11 0,000 9,553E-03 0,02212213 ! temperature homeostasis GO:0001659 18 11 0,000 9,553E-03 0,02210118 ! behavioral fear response GO:0001662 27 11 0,000 9,553E-03 0,02208027 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 9,553E-03 0,0220594 ! negative regulation of ossification GO:0030279 27 11 0,000 9,553E-03 0,02203857 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 9,553E-03 0,02201778 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 9,553E-03 0,02199703 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 9,553E-03 0,02197631 ! alpha-beta T cell activation GO:0046631 26 11 0,000 9,553E-03 0,02195564 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 9,553E-03 0,021935 ! regulation of organ growth GO:0046620 14 11 0,000 9,553E-03 0,02191441 ! pigment granule localization GO:0051875 20 11 0,000 9,553E-03 0,02189385 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 9,553E-03 0,02187333 ! vasoconstriction GO:0042310 20 11 0,000 9,553E-03 0,02185285 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 9,553E-03 0,02183241 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,553E-03 0,021812 ! embryonic axis specification GO:0000578 19 11 0,000 9,553E-03 0,02179164 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 9,553E-03 0,02177131 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,553E-03 0,02175102 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 9,553E-03 0,02173077 ! nitric oxide metabolic process GO:0046209 17 11 0,000 9,553E-03 0,02171055 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,553E-03 0,02169038 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 9,553E-03 0,02167024 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 9,553E-03 0,02165013 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 9,553E-03 0,02163007 ! prophase GO:0051324 17 11 0,000 9,553E-03 0,02161004 ! neuroblast proliferation GO:0007405 25 11 0,000 9,553E-03 0,02159005 ! nucleosome positioning GO:0016584 15 11 0,000 9,553E-03 0,0215701 ! regulation of isotype switching GO:0045191 24 11 0,000 9,553E-03 0,02155018 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 9,553E-03 0,0215303 ! negative regulation of neurological system process GO:0031645 21 11 0,000 9,553E-03 0,02151046 ! apical protein localization GO:0045176 18 11 0,000 9,553E-03 0,02149065 ! acid secretion GO:0046717 20 11 0,000 9,553E-03 0,02147088 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,553E-03 0,02145114 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 9,553E-03 0,02143145 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 9,553E-03 0,02141178 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 9,553E-03 0,02139216 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 9,553E-03 0,02137257 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 9,553E-03 0,02135301 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 9,553E-03 0,0213335 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,553E-03 0,02131401 ! oocyte development GO:0048599 20 11 0,000 9,553E-03 0,02129457 ! negative regulation of glucose import GO:0046325 18 11 0,000 9,553E-03 0,02127515 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 9,553E-03 0,02125578 ! embryonic gut development GO:0048566 19 11 0,000 9,553E-03 0,02123644 ! regulation of organic acid transport GO:0032890 19 11 0,000 9,553E-03 0,02121713 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 9,553E-03 0,02119786 ! activation of innate immune response GO:0002218 16 11 0,000 9,553E-03 0,02117862 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 9,553E-03 0,02115942 ! cardiac cell differentiation GO:0035051 36 11 0,000 9,553E-03 0,02114026 ! lysogeny GO:0030069 22 11 0,000 9,553E-03 0,02112113 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,553E-03 0,02110203 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 9,553E-03 0,02108297 ! sequestering of metal ion GO:0051238 15 11 0,000 9,553E-03 0,02106394 ! regulation of embryonic development GO:0045995 35 11 0,000 9,553E-03 0,02104494 ! nucleus localization GO:0051647 22 11 0,000 9,553E-03 0,02102599 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01041745 0,02290713 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01041745 0,02288653 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01041745 0,02286597 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01041745 0,02284544 ! virus-host interaction GO:0019048 30 12 0,000 0,01041745 0,02282496 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01041745 0,0228045 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01041745 0,02278409 ! protein complex disassembly GO:0043241 28 12 0,000 0,01041745 0,02276371 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01041745 0,02274336 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01041745 0,02272306 ! hippocampus development GO:0021766 29 12 0,000 0,01041745 0,02270279 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01041745 0,02268255 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01041745 0,02266236 ! T cell proliferation GO:0042098 32 12 0,000 0,01041745 0,02264219 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01041745 0,02262207 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01041745 0,02260198 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01041745 0,02258192 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01041745 0,0225619 ! drug transport GO:0015893 16 12 0,000 0,01041745 0,02254192 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01041745 0,02252197 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01041745 0,02250206 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01041745 0,02248218 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01041745 0,02246233 ! focal adhesion formation GO:0048041 37 12 0,000 0,01041745 0,02244253 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01041745 0,02242275 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01041745 0,02240302 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01041745 0,02238331 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01041745 0,02236364 ! lipid digestion GO:0044241 21 12 0,000 0,01041745 0,02234401 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01041745 0,02232441 ! entry into host cell GO:0030260 34 12 0,000 0,01041745 0,02230484 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01041745 0,02228531 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01041745 0,02226581 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01041745 0,02224635 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01041745 0,02222692 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01041745 0,02220753 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01041745 0,02218816 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01041745 0,02216884 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01041745 0,02214954 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01041745 0,02213028 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01041745 0,02211106 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01041745 0,02209186 ! cranial nerve development GO:0021545 23 12 0,000 0,01041745 0,0220727 ! fucose catabolic process GO:0019317 25 12 0,000 0,01041745 0,02205357 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01041745 0,02203448 ! histone acetylation GO:0016573 27 12 0,000 0,01041745 0,02201542 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01041745 0,02199639 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01041745 0,0219774 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01041745 0,02195843 ! zymogen activation GO:0031638 18 12 0,000 0,01041745 0,0219395 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01041745 0,02192061 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01041745 0,02190174 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01041745 0,02188291 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01041745 0,02186411 ! oocyte differentiation GO:0009994 21 12 0,000 0,01041745 0,02184534 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01041745 0,02182661 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01041745 0,0218079 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01041745 0,02178923 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01041745 0,02177059 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01041745 0,02175199 ! defense response to fungus GO:0050832 15 12 0,000 0,01041745 0,02173341 ! developmental induction GO:0031128 22 12 0,000 0,01041745 0,02171487 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01041745 0,02169636 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01041745 0,02167787 ! response to cold GO:0009409 17 12 0,000 0,01041745 0,02165943 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01041745 0,02164101 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01041745 0,02162262 ! localization within membrane GO:0051668 26 12 0,000 0,01041745 0,02160427 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01128081 0,02337491 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01128081 0,02335511 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01128081 0,02333533 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01128081 0,02331559 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01128081 0,02329588 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01128081 0,0232762 ! peroxisomal transport GO:0043574 28 13 0,000 0,01128081 0,02325656 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01128081 0,02323695 ! cartilage condensation GO:0001502 22 13 0,000 0,01128081 0,02321737 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01128081 0,02319783 ! organelle fusion GO:0048284 36 13 0,000 0,01128081 0,02317832 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01128081 0,02315884 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01128081 0,0231394 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01128081 0,02311999 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01128081 0,02310061 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01128081 0,02308126 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01128081 0,02306194 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01128081 0,02304266 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01128081 0,02302341 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01128081 0,02300419 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01128081 0,02298501 ! methionine metabolic process GO:0006555 31 13 0,000 0,01128081 0,02296585 ! plasma membrane organization GO:0007009 27 13 0,000 0,01128081 0,02294673 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01128081 0,02292764 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01128081 0,02290858 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01128081 0,02288955 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01128081 0,02287056 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01128081 0,0228516 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01128081 0,02283266 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01128081 0,02281376 ! exocrine system development GO:0035272 34 13 0,000 0,01128081 0,02279489 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01128081 0,02277605 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01128081 0,02275725 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01128081 0,02273847 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01128081 0,02271972 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01128081 0,02270101 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01128081 0,02268232 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01128081 0,02266367 ! protein homotetramerization GO:0051289 24 13 0,000 0,01128081 0,02264505 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01128081 0,02262646 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01128081 0,02260789 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01128081 0,02258936 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01128081 0,02257086 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01128081 0,02255239 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01128081 0,02253395 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01128081 0,02251554 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01128081 0,02249716 ! histone methylation GO:0016571 29 13 0,000 0,01128081 0,02247881 ! chromatin silencing GO:0006342 29 13 0,000 0,01128081 0,02246049 ! gland morphogenesis GO:0022612 31 13 0,000 0,01128081 0,0224422 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01128081 0,02242394 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01128081 0,02240571 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01128081 0,02238751 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01128081 0,02236934 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01128081 0,0223512 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01128081 0,02233308 ! spleen development GO:0048536 24 13 0,000 0,01128081 0,022315 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01128081 0,02229694 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01128081 0,02227892 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01128081 0,02226092 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01128081 0,02224296 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01128081 0,02222502 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01128081 0,02220711 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01128081 0,02218923 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01128081 0,02217138 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01128081 0,02215356 ! insulin secretion GO:0030073 24 13 0,000 0,01128081 0,02213576 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01128081 0,022118 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01128081 0,02210026 ! acrosome reaction GO:0007340 19 13 0,000 0,01128081 0,02208255 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01128081 0,02206487 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01128081 0,02204722 ! rRNA transcription GO:0009303 28 14 0,000 0,01214345 0,02371418 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01214345 0,02369524 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01214345 0,02367633 ! water transport GO:0006833 21 14 0,000 0,01214345 0,02365745 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01214345 0,0236386 ! non-recombinational repair GO:0000726 29 14 0,000 0,01214345 0,02361978 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01214345 0,02360099 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01214345 0,02358223 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01214345 0,0235635 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01214345 0,0235448 ! lipid localization GO:0010876 32 14 0,000 0,01214345 0,02352612 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01214345 0,02350748 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01214345 0,02348887 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01214345 0,02347029 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01214345 0,02345173 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01214345 0,02343321 ! arginine metabolic process GO:0006525 21 14 0,000 0,01214345 0,02341471 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01214345 0,02339625 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01214345 0,02337781 ! regulation of heart rate GO:0002027 25 14 0,000 0,01214345 0,0233594 ! fear response GO:0042596 34 14 0,000 0,01214345 0,02334102 ! organic alcohol transport GO:0015850 29 14 0,000 0,01214345 0,02332267 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01214345 0,02330435 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01214345 0,02328606 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01214345 0,0232678 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01214345 0,02324956 ! bone mineralization GO:0030282 18 14 0,000 0,01214345 0,02323136 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01214345 0,02321318 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01214345 0,02319503 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01214345 0,02317691 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01214345 0,02315882 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01214345 0,02314075 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01214345 0,02312271 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01214345 0,02310471 ! ribosome assembly GO:0042255 18 14 0,000 0,01214345 0,02308673 ! cerebellum development GO:0021549 23 14 0,000 0,01214345 0,02306877 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01214345 0,02305085 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01214345 0,02303295 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01214345 0,02301508 ! response to gamma radiation GO:0010332 30 14 0,000 0,01214345 0,02299724 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01214345 0,02297943 ! NADP metabolic process GO:0006739 24 14 0,000 0,01214345 0,02296164 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01214345 0,02294388 ! oxygen transport GO:0015671 22 14 0,000 0,01214345 0,02292615 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01214345 0,02290845 ! male genitalia development GO:0030539 26 14 0,000 0,01214345 0,02289077 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01214345 0,02287312 ! regulation of axon extension GO:0030516 43 14 0,000 0,01214345 0,0228555 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01214345 0,02283791 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01214345 0,02282034 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01214345 0,0228028 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01300535 0,02440252 ! lactation GO:0007595 30 15 0,000 0,01300535 0,02438379 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01300535 0,02436509 ! reproductive cellular process GO:0048610 22 15 0,000 0,01300535 0,02434642 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01300535 0,02432778 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01300535 0,02430917 ! superoxide anion generation GO:0042554 22 15 0,000 0,01300535 0,02429058 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01300535 0,02427202 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01300535 0,0242535 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01300535 0,024235 ! copper ion transport GO:0006825 22 15 0,000 0,01300535 0,02421652 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01300535 0,02419808 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01300535 0,02417967 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01300535 0,02416128 ! sulfate transport GO:0008272 27 15 0,000 0,01300535 0,02414292 ! response to cAMP GO:0051591 25 15 0,000 0,01300535 0,02412459 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01300535 0,02410628 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01300535 0,02408801 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01300535 0,02406976 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01300535 0,02405154 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01300535 0,02403334 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01300535 0,02401518 ! vesicle coating GO:0006901 38 15 0,000 0,01300535 0,02399704 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01300535 0,02397893 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01300535 0,02396085 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01300535 0,02394279 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01300535 0,02392476 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01300535 0,02390676 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01300535 0,02388878 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01300535 0,02387083 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01300535 0,02385291 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01300535 0,02383502 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01300535 0,02381715 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01300535 0,02379931 ! histone deacetylation GO:0016575 24 15 0,000 0,01300535 0,0237815 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01300535 0,02376371 ! water homeostasis GO:0030104 28 15 0,000 0,01300535 0,02374595 ! cofactor transport GO:0051181 30 15 0,000 0,01300535 0,02372822 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01300535 0,02371051 ! muscle maintenance GO:0046716 26 15 0,000 0,01300535 0,02369283 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01300535 0,02367517 ! intestinal absorption GO:0050892 31 15 0,000 0,01300535 0,02365754 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01300535 0,02363994 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01300535 0,02362236 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01300535 0,02360481 ! cell killing GO:0001906 32 15 0,000 0,01300535 0,02358729 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01300535 0,02356979 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01300535 0,02355232 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01300535 0,02353487 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01300535 0,02351745 ! actin filament polymerization GO:0030041 27 15 0,000 0,01300535 0,02350006 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01300535 0,02348269 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01386653 0,02501916 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01386653 0,02500069 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01386653 0,02498226 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01386653 0,02496385 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01386653 0,02494546 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01386653 0,02492711 ! bone remodeling GO:0046849 28 16 0,000 0,01386653 0,02490878 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01386653 0,02489048 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01386653 0,0248722 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01386653 0,02485396 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01386653 0,02483573 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01386653 0,02481754 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01386653 0,02479937 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01386653 0,02478123 ! startle response GO:0001964 28 16 0,000 0,01386653 0,02476311 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01386653 0,02474503 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01386653 0,02472696 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01386653 0,02470893 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01386653 0,02469092 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01386653 0,02467294 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01386653 0,02465498 ! pituitary gland development GO:0021983 30 16 0,000 0,01386653 0,02463705 ! response to osmotic stress GO:0006970 27 16 0,000 0,01386653 0,02461914 ! lysosomal transport GO:0007041 31 16 0,000 0,01386653 0,02460126 ! fructose metabolic process GO:0006000 25 16 0,000 0,01386653 0,02458341 ! L-amino acid transport GO:0015807 33 16 0,000 0,01386653 0,02456558 ! stem cell development GO:0048864 46 16 0,000 0,01386653 0,02454778 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01386653 0,02453001 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01386653 0,02451226 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01386653 0,02449453 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01386653 0,02447684 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01386653 0,02445916 ! axon cargo transport GO:0008088 46 16 0,000 0,01386653 0,02444152 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01386653 0,02442389 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01386653 0,0244063 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01386653 0,02438873 ! DNA replication initiation GO:0006270 28 16 0,000 0,01386653 0,02437118 ! neuron recognition GO:0008038 40 16 0,000 0,01386653 0,02435366 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01386653 0,02433616 ! tissue regeneration GO:0042246 27 16 0,000 0,01386653 0,02431869 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01386653 0,02430125 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01386653 0,02428383 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01386653 0,02426643 ! biomineral formation GO:0031214 22 16 0,000 0,01386653 0,02424906 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01386653 0,02423172 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01386653 0,0242144 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01386653 0,0241971 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01386653 0,02417983 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01386653 0,02416258 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01386653 0,02414536 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01386653 0,02412816 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01386653 0,02411099 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01386653 0,02409384 ! peptide hormone processing GO:0016486 27 16 0,000 0,01386653 0,02407672 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01472699 0,02555257 ! metencephalon development GO:0022037 32 17 0,000 0,01472699 0,02553444 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01472699 0,02551633 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01472699 0,02549825 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01472699 0,02548019 ! signal complex assembly GO:0007172 47 17 0,000 0,01472699 0,02546216 ! filopodium assembly GO:0046847 42 17 0,000 0,01472699 0,02544415 ! endothelial cell migration GO:0043542 31 17 0,000 0,01472699 0,02542617 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01472699 0,02540821 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01472699 0,02539028 ! glial cell development GO:0021782 28 17 0,000 0,01472699 0,02537237 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01472699 0,02535449 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01472699 0,02533664 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01472699 0,02531881 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01472699 0,025301 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01472699 0,02528322 ! myoblast differentiation GO:0045445 50 17 0,000 0,01472699 0,02526547 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01472699 0,02524774 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01472699 0,02523003 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01472699 0,02521235 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01472699 0,0251947 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01472699 0,02517706 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01472699 0,02515946 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01472699 0,02514188 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01472699 0,02512432 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01472699 0,02510679 ! membrane budding GO:0006900 42 17 0,000 0,01472699 0,02508928 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01472699 0,02507179 ! regulation of protein binding GO:0043393 33 17 0,000 0,01472699 0,02505434 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01472699 0,0250369 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01472699 0,02501949 ! genitalia development GO:0048806 32 17 0,000 0,01472699 0,0250021 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01472699 0,02498474 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01472699 0,0249674 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01472699 0,02495009 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01472699 0,0249328 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01472699 0,02491553 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01472699 0,02489829 ! steroid catabolic process GO:0006706 34 17 0,000 0,01472699 0,02488107 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01472699 0,02486387 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01472699 0,0248467 ! gas transport GO:0015669 26 17 0,000 0,01472699 0,02482956 ! organic cation transport GO:0015695 32 17 0,000 0,01472699 0,02481243 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01472699 0,02479533 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01472699 0,02477825 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01472699 0,0247612 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01558671 0,02618868 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01558671 0,02617068 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01558671 0,0261527 ! limbic system development GO:0021761 40 18 0,000 0,01558671 0,02613475 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01558671 0,02611683 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01558671 0,02609893 ! adult walking behavior GO:0007628 36 18 0,000 0,01558671 0,02608105 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01558671 0,0260632 ! heart looping GO:0001947 34 18 0,000 0,01558671 0,02604537 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01558671 0,02602757 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01558671 0,02600979 ! centrosome cycle GO:0007098 26 18 0,000 0,01558671 0,02599204 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01558671 0,02597431 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01558671 0,0259566 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01558671 0,02593892 ! glycine metabolic process GO:0006544 30 18 0,000 0,01558671 0,02592126 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01558671 0,02590363 ! response to retinoic acid GO:0032526 31 18 0,000 0,01558671 0,02588602 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01558671 0,02586843 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01558671 0,02585087 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01558671 0,02583333 ! DNA integration GO:0015074 32 18 0,000 0,01558671 0,02581582 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01558671 0,02579833 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01558671 0,02578086 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01558671 0,02576342 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01558671 0,025746 ! neural crest cell migration GO:0001755 41 18 0,000 0,01558671 0,0257286 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01558671 0,02571123 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01558671 0,02569388 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01558671 0,02567656 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01558671 0,02565926 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01558671 0,02564198 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01558671 0,02562472 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01558671 0,02560749 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01558671 0,02559028 ! detection of bacterium GO:0016045 22 18 0,000 0,01558671 0,02557309 ! nerve development GO:0021675 34 18 0,000 0,01558671 0,02555593 ! defense response to virus GO:0051607 43 18 0,000 0,01558671 0,02553879 ! microspike assembly GO:0030035 46 18 0,000 0,01558671 0,02552167 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01558671 0,02550458 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01558671 0,02548751 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01644571 0,02687416 ! positive regulation of translation GO:0045727 31 19 0,000 0,01644571 0,0268562 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01644571 0,02683826 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01644571 0,02682034 ! neuron maturation GO:0042551 46 19 0,000 0,01644571 0,02680245 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01644571 0,02678458 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01644571 0,02676674 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01644571 0,02674891 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01644571 0,02673112 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01644571 0,02671334 ! inositol metabolic process GO:0006020 33 19 0,000 0,01644571 0,02669559 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01644571 0,02667787 ! memory GO:0007613 34 19 0,000 0,01644571 0,02666017 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01644571 0,02664249 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01644571 0,02662483 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01644571 0,0266072 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01644571 0,02658959 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01644571 0,026572 ! cerebral cortex development GO:0021987 40 19 0,000 0,01644571 0,02655444 ! pigmentation during development GO:0048066 42 19 0,000 0,01644571 0,0265369 ! response to vitamin A GO:0033189 32 19 0,000 0,01644571 0,02651939 ! heme metabolic process GO:0042168 40 19 0,000 0,01644571 0,02650189 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01644571 0,02648442 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01644571 0,02646698 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01644571 0,02644955 ! response to fungus GO:0009620 26 19 0,000 0,01644571 0,02643215 ! peptide cross-linking GO:0018149 39 19 0,000 0,01644571 0,02641477 ! protein export from nucleus GO:0006611 40 19 0,000 0,01644571 0,02639742 ! heart process GO:0003015 32 19 0,000 0,01644571 0,02638009 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01644571 0,02636278 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01644571 0,02634549 ! visual learning GO:0008542 38 19 0,000 0,01644571 0,02632822 ! cellular pigmentation GO:0033059 37 19 0,000 0,01644571 0,02631098 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01644571 0,02629376 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01644571 0,02627657 ! vitamin transport GO:0051180 31 19 0,000 0,01644571 0,02625939 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01644571 0,02624224 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01644571 0,02622511 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01644571 0,026208 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01644571 0,02619092 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01644571 0,02617386 ! cilium assembly GO:0042384 38 19 0,000 0,01644571 0,02615682 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01644571 0,0261398 ! protein secretion GO:0009306 45 20 0,000 0,01730398 0,02748611 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01730398 0,02746825 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01730398 0,02745041 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01730398 0,0274326 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01730398 0,02741481 ! skin development GO:0043588 42 20 0,000 0,01730398 0,02739704 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01730398 0,0273793 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01730398 0,02736157 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01730398 0,02734388 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01730398 0,0273262 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01730398 0,02730855 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01730398 0,02729092 ! response to vitamin GO:0033273 36 20 0,000 0,01730398 0,02727331 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01730398 0,02725573 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01730398 0,02723817 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01730398 0,02722063 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01730398 0,02720311 ! response to alkaloid GO:0043279 38 20 0,000 0,01730398 0,02718562 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01730398 0,02716814 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01730398 0,0271507 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01730398 0,02713327 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01730398 0,02711586 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01730398 0,02709848 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01730398 0,02708112 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01730398 0,02706379 ! body fluid secretion GO:0007589 33 20 0,000 0,01730398 0,02704647 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01730398 0,02702918 ! peptide secretion GO:0002790 38 20 0,000 0,01730398 0,02701191 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01730398 0,02699466 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01730398 0,02697743 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01730398 0,02696023 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01730398 0,02694304 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01730398 0,02692588 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01730398 0,02690874 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01730398 0,02689162 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01730398 0,02687453 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01730398 0,02685745 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01730398 0,0268404 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01730398 0,02682337 ! regulation of glucose import GO:0046324 30 20 0,000 0,01730398 0,02680636 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01730398 0,02678937 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01730398 0,02677241 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01730398 0,02675546 ! negative regulation of translation GO:0017148 32 20 0,000 0,01730398 0,02673854 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01730398 0,02672164 ! regulation of cell killing GO:0031341 46 21 0,000 0,01816153 0,02802819 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01816153 0,0280105 ! hormone secretion GO:0046879 39 21 0,000 0,01816153 0,02799282 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01816153 0,02797517 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01816153 0,02795755 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01816153 0,02793994 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01816153 0,02792236 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01816153 0,0279048 ! ovarian follicle development GO:0001541 39 21 0,000 0,01816153 0,02788726 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01816153 0,02786974 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01816153 0,02785224 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01816153 0,02783477 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01816153 0,02781732 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01816153 0,02779989 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01816153 0,02778248 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01816153 0,0277651 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01816153 0,02774773 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01816153 0,02773039 ! sensory perception of pain GO:0019233 33 21 0,000 0,01816153 0,02771307 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01816153 0,02769577 ! diencephalon development GO:0021536 36 21 0,000 0,01816153 0,02767849 ! collagen fibril organization GO:0030199 62 21 0,000 0,01816153 0,02766124 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01816153 0,027644 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01816153 0,02762679 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01816153 0,0276096 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01816153 0,02759243 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01816153 0,02757528 ! collagen catabolic process GO:0030574 29 21 0,000 0,01816153 0,02755815 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01816153 0,02754105 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01816153 0,02752396 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01816153 0,0275069 ! actin filament-based movement GO:0030048 47 21 0,000 0,01816153 0,02748986 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01816153 0,02747283 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01901836 0,02875114 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01901836 0,02873336 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01901836 0,02871561 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01901836 0,02869787 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01901836 0,02868015 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01901836 0,02866246 ! microtubule-based transport GO:0010970 59 22 0,000 0,01901836 0,02864479 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01901836 0,02862714 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01901836 0,02860951 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01901836 0,02859191 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01901836 0,02857432 ! cellular response to starvation GO:0009267 37 22 0,000 0,01901836 0,02855676 ! vacuolar transport GO:0007034 41 22 0,000 0,01901836 0,02853922 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01901836 0,0285217 ! fucose metabolic process GO:0006004 44 22 0,000 0,01901836 0,0285042 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01901836 0,02848673 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01901836 0,02846927 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01901836 0,02845184 ! ureteric bud development GO:0001657 50 22 0,000 0,01901836 0,02843442 ! cell aging GO:0007569 48 22 0,000 0,01901836 0,02841703 ! stem cell differentiation GO:0048863 57 22 0,000 0,01901836 0,02839966 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01901836 0,02838231 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01901836 0,02836499 ! cytolysis GO:0019835 27 22 0,000 0,01901836 0,02834768 ! renal system process GO:0003014 42 22 0,000 0,01901836 0,0283304 ! vasodilation GO:0042311 40 22 0,000 0,01901836 0,02831313 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01901836 0,02829589 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01901836 0,02827867 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01901836 0,02826147 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01901836 0,02824429 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01901836 0,02822713 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01901836 0,02820999 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01901836 0,02819287 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01901836 0,02817577 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01901836 0,0281587 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01901836 0,02814164 ! sarcomere organization GO:0045214 32 22 0,000 0,01901836 0,02812461 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01901836 0,02810759 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01901836 0,0280906 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01901836 0,02807362 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01901836 0,02805667 ! gut development GO:0048565 44 22 0,000 0,01901836 0,02803974 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01901836 0,02802283 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01901836 0,02800594 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01901836 0,02798907 ! protein stabilization GO:0050821 41 22 0,000 0,01901836 0,02797222 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01987446 0,02921378 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01987446 0,02919621 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01987446 0,02917867 ! gluconeogenesis GO:0006094 38 23 0,000 0,01987446 0,02916114 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01987446 0,02914364 ! viral genome replication GO:0019079 44 23 0,000 0,01987446 0,02912616 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01987446 0,0291087 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01987446 0,02909126 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01987446 0,02907384 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01987446 0,02905644 ! regeneration GO:0031099 42 23 0,000 0,01987446 0,02903906 ! axis specification GO:0009798 43 23 0,000 0,01987446 0,0290217 ! visual behavior GO:0007632 46 23 0,000 0,01987446 0,02900436 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01987446 0,02898705 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01987446 0,02896975 ! response to ethanol GO:0045471 47 23 0,000 0,01987446 0,02895248 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01987446 0,02893522 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01987446 0,02891799 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01987446 0,02890078 ! peroxisome organization GO:0007031 43 23 0,000 0,01987446 0,02888358 ! lysosome organization GO:0007040 47 23 0,000 0,01987446 0,02886641 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01987446 0,02884926 ! vesicle targeting GO:0006903 49 23 0,000 0,01987446 0,02883213 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01987446 0,02881502 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01987446 0,02879793 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01987446 0,02878086 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01987446 0,02876381 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01987446 0,02874678 ! DNA modification GO:0006304 36 23 0,000 0,01987446 0,02872977 ! fatty acid transport GO:0015908 47 23 0,000 0,01987446 0,02871278 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01987446 0,02869581 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01987446 0,02867886 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01987446 0,02866193 ! hormone transport GO:0009914 41 23 0,000 0,01987446 0,02864502 ! cell-cell recognition GO:0009988 28 23 0,000 0,01987446 0,02862813 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01987446 0,02861126 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01987446 0,02859441 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01987446 0,02857758 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02072984 0,02979 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02072984 0,02977248 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02072984 0,02975499 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02072984 0,02973752 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02072984 0,02972007 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02072984 0,02970264 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02072984 0,02968523 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02072984 0,02966783 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02072984 0,02965046 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02072984 0,02963312 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02072984 0,02961579 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02072984 0,02959848 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02072984 0,02958119 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02072984 0,02956392 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02072984 0,02954667 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02072984 0,02952944 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02072984 0,02951223 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02072984 0,02949505 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02072984 0,02947788 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02072984 0,02946073 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02072984 0,0294436 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02072984 0,02942649 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02072984 0,0294094 ! membrane depolarization GO:0051899 45 24 0,000 0,02072984 0,02939234 ! pallium development GO:0021543 56 24 0,000 0,02072984 0,02937529 ! oogenesis GO:0048477 44 24 0,000 0,02072984 0,02935826 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02072984 0,02934125 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02072984 0,02932426 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02072984 0,02930729 ! platelet activation GO:0030168 41 24 0,000 0,02072984 0,02929034 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02072984 0,02927341 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02072984 0,0292565 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02072984 0,0292396 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02072984 0,02922273 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02072984 0,02920588 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02072984 0,02918905 ! regulation of amine transport GO:0051952 41 24 0,000 0,02072984 0,02917223 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02072984 0,02915544 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02158449 0,03034 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02158449 0,03032255 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02158449 0,03030513 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02158449 0,03028772 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02158449 0,03027033 ! phototransduction GO:0007602 37 25 0,000 0,02158449 0,03025297 ! keratinization GO:0031424 37 25 0,000 0,02158449 0,03023562 ! vasculogenesis GO:0001570 49 25 0,000 0,02158449 0,03021829 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02158449 0,03020098 ! vacuole organization GO:0007033 49 25 0,000 0,02158449 0,0301837 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02158449 0,03016643 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02158449 0,03014918 ! receptor metabolic process GO:0043112 53 25 0,000 0,02158449 0,03013195 ! chromosome condensation GO:0030261 48 25 0,000 0,02158449 0,03011474 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02158449 0,03009756 ! regulation of behavior GO:0050795 48 25 0,000 0,02158449 0,03008039 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02158449 0,03006324 ! interaction with host GO:0051701 66 25 0,000 0,02158449 0,03004611 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02158449 0,030029 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02158449 0,03001191 ! immunoglobulin production GO:0002377 62 25 0,000 0,02158449 0,02999483 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02158449 0,02997778 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02158449 0,02996075 ! liver development GO:0001889 55 25 0,000 0,02158449 0,02994374 ! protein tetramerization GO:0051262 57 25 0,000 0,02158449 0,02992674 ! myelination GO:0042552 50 26 0,000 0,02243843 0,03109307 ! initiation of viral infection GO:0019059 60 26 0,000 0,02243843 0,03107544 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02243843 0,03105784 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02243843 0,03104025 ! molting cycle process GO:0022404 52 26 0,000 0,02243843 0,03102268 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02243843 0,03100514 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02243843 0,03098761 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02243843 0,0309701 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02243843 0,03095261 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02243843 0,03093515 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02243843 0,0309177 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02243843 0,03090027 ! digestive system process GO:0022600 49 26 0,000 0,02243843 0,03088286 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02243843 0,03086547 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02243843 0,0308481 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02243843 0,03083075 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02243843 0,03081342 ! neural crest cell development GO:0014032 59 26 0,000 0,02243843 0,03079611 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02243843 0,03077882 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02243843 0,03076155 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02243843 0,0307443 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02243843 0,03072706 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02243843 0,03070985 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02243843 0,03069265 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02243843 0,03067548 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02243843 0,03065832 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,02243843 0,03064118 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02243843 0,03062407 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02243843 0,03060697 ! blastocyst development GO:0001824 50 26 0,000 0,02243843 0,03058989 ! telomere organization GO:0032200 46 26 0,000 0,02243843 0,03057283 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02243843 0,03055579 ! neural tube closure GO:0001843 58 26 0,000 0,02243843 0,03053876 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,02243843 0,03052176 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02243843 0,03050477 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02243843 0,03048781 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02329164 0,0316295 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02329164 0,03161193 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02329164 0,03159438 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02329164 0,03157685 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02329164 0,03155933 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02329164 0,03154184 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02329164 0,03152436 ! iron ion transport GO:0006826 65 27 0,000 0,02329164 0,03150691 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02329164 0,03148947 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02329164 0,03147206 ! tube lumen formation GO:0035148 59 27 0,000 0,02329164 0,03145466 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02329164 0,03143728 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02329164 0,03141992 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02329164 0,03140258 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02329164 0,03138526 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02329164 0,03136796 ! response to starvation GO:0042594 47 27 0,000 0,02329164 0,03135068 ! response to toxin GO:0009636 49 27 0,000 0,02329164 0,03133341 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02329164 0,03131617 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02329164 0,03129894 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02329164 0,03128174 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02329164 0,03126455 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02329164 0,03124738 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02329164 0,03123023 ! neuron fate commitment GO:0048663 52 28 0,000 0,02414413 0,03235552 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02414413 0,03233778 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02414413 0,03232006 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02414413 0,03230236 ! vesicle docking GO:0048278 55 28 0,000 0,02414413 0,03228468 ! circadian rhythm GO:0007623 56 28 0,000 0,02414413 0,03226702 ! dendrite development GO:0016358 67 28 0,000 0,02414413 0,03224938 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02414413 0,03223176 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02414413 0,03221415 ! sperm motility GO:0030317 37 28 0,000 0,02414413 0,03219657 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02414413 0,032179 ! base-excision repair GO:0006284 41 28 0,000 0,02414413 0,03216146 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02414413 0,03214393 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02414413 0,03212642 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02414413 0,03210894 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02414413 0,03209147 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02414413 0,03207402 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02414413 0,03205658 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02414413 0,03203917 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02414413 0,03202178 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02414413 0,0320044 ! lipid oxidation GO:0034440 48 28 0,000 0,02414413 0,03198705 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02414413 0,03196971 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02414413 0,03195239 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,0249959 0,03306172 ! translational initiation GO:0006413 66 29 0,000 0,0249959 0,03304383 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,0249959 0,03302596 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,0249959 0,03300811 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,0249959 0,03299027 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,0249959 0,03297246 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,0249959 0,03295467 ! primary neural tube formation GO:0014020 61 29 0,000 0,0249959 0,03293689 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,0249959 0,03291913 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,0249959 0,0329014 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,0249959 0,03288368 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,0249959 0,03286598 ! somitogenesis GO:0001756 52 29 0,000 0,0249959 0,0328483 ! synaptogenesis GO:0007416 46 29 0,000 0,0249959 0,03283064 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,0249959 0,032813 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,0249959 0,03279538 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,0249959 0,03277777 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,0249959 0,03276019 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02584696 0,03385743 ! phenol metabolic process GO:0018958 56 30 0,000 0,02584696 0,03383929 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02584696 0,03382117 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02584696 0,03380306 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02584696 0,03378497 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02584696 0,03376691 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02584696 0,03374886 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02584696 0,03373083 ! acute-phase response GO:0006953 50 30 0,000 0,02584696 0,03371282 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02584696 0,03369483 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02584696 0,03367686 ! myofibril assembly GO:0030239 50 30 0,000 0,02584696 0,03365891 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02584696 0,03364098 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,02584696 0,03362306 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02584696 0,03360517 ! cell fate determination GO:0001709 64 30 0,000 0,02584696 0,0335873 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02584696 0,03356944 ! phospholipid transport GO:0015914 65 30 0,000 0,02584696 0,0335516 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02584696 0,03353378 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02584696 0,03351598 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02584696 0,0334982 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02584696 0,03348044 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02584696 0,0334627 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,02584696 0,03344498 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,02669729 0,03452699 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,02669729 0,03450872 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,02669729 0,03449047 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,02669729 0,03447224 ! cell junction assembly GO:0034329 85 31 0,000 0,02669729 0,03445403 ! regulation of innate immune response GO:0045088 57 31 0,000 0,02669729 0,03443584 ! ovulation cycle process GO:0022602 55 31 0,000 0,02669729 0,03441767 ! peptide transport GO:0015833 60 31 0,000 0,02669729 0,03439951 ! male gonad development GO:0008584 56 31 0,000 0,02669729 0,03438138 ! iron ion homeostasis GO:0055072 60 31 0,000 0,02669729 0,03436327 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,02669729 0,03434517 ! detection of light stimulus GO:0009583 44 31 0,000 0,02669729 0,03432709 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,02669729 0,03430904 ! natural killer cell activation GO:0030101 50 31 0,000 0,02669729 0,034291 ! ensheathment of neurons GO:0007272 64 31 0,000 0,02669729 0,03427298 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,02669729 0,03425498 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,02669729 0,034237 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,02669729 0,03421903 ! eye morphogenesis GO:0048592 65 31 0,000 0,02669729 0,03420109 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,02669729 0,03418317 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02754691 0,03525254 ! collagen metabolic process GO:0032963 49 32 0,000 0,02754691 0,03523408 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02754691 0,03521564 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02754691 0,03519722 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02754691 0,03517882 ! metanephros development GO:0001656 81 32 0,000 0,02754691 0,03516044 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02754691 0,03514208 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,02754691 0,03512374 ! muscle cell development GO:0055001 52 32 0,000 0,02754691 0,03510542 ! mesoderm formation GO:0001707 73 32 0,000 0,02754691 0,03508712 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,02754691 0,03506883 ! ovulation cycle GO:0042698 57 32 0,000 0,02754691 0,03505057 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02754691 0,03503232 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02754691 0,03501409 ! hindbrain development GO:0030902 65 32 0,000 0,02754691 0,03499589 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02754691 0,0349777 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02754691 0,03495953 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02754691 0,03494138 ! gene silencing GO:0016458 71 32 0,000 0,02754691 0,03492324 ! regulation of pH GO:0006885 56 33 0,000 0,0283958 0,03598078 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,0283958 0,03596213 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,0283958 0,0359435 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,0283958 0,03592488 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,0283958 0,03590629 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,0283958 0,03588771 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,0283958 0,03586916 ! response to ionizing radiation GO:0010212 74 33 0,000 0,0283958 0,03585062 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,0283958 0,0358321 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,0283958 0,0358136 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,0283958 0,03579512 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,0283958 0,03577666 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,0283958 0,03575822 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,0283958 0,0357398 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,0283958 0,03572139 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,02924398 0,03676945 ! glial cell differentiation GO:0010001 67 34 0,000 0,02924398 0,03675054 ! post-embryonic development GO:0009791 76 34 0,000 0,02924398 0,03673165 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,02924398 0,03671277 ! cholesterol transport GO:0030301 62 34 0,000 0,02924398 0,03669391 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,02924398 0,03667508 ! spliceosome assembly GO:0000245 75 34 0,000 0,02924398 0,03665626 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,02924398 0,03663746 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,02924398 0,03661868 ! formation of primary germ layer GO:0001704 76 34 0,000 0,02924398 0,03659992 ! cell fate specification GO:0001708 56 34 0,000 0,02924398 0,03658118 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,02924398 0,03656246 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,02924398 0,03654376 ! adult locomotory behavior GO:0008344 62 34 0,000 0,02924398 0,03652508 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,02924398 0,03650641 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03009145 0,03754515 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03009145 0,03752599 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03009145 0,03750684 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03009145 0,03748771 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03009145 0,03746861 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03009145 0,03744952 ! membrane docking GO:0022406 69 35 0,000 0,03009145 0,03743045 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03009145 0,0374114 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03009145 0,03739237 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03009145 0,03737336 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03009145 0,03735437 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03009145 0,0373354 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03009145 0,03731645 ! telencephalon development GO:0021537 81 35 0,000 0,03009145 0,03729752 ! sterol transport GO:0015918 63 35 0,000 0,03009145 0,0372786 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03009145 0,03725971 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03009145 0,03724083 ! placenta development GO:0001890 53 35 0,000 0,03009145 0,03722198 ! vesicle localization GO:0051648 70 35 0,000 0,03009145 0,03720314 ! regulation of muscle development GO:0048634 82 36 0,000 0,03093819 0,03823066 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03093819 0,03821133 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03093819 0,03819202 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03093819 0,03817273 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03093819 0,03815346 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03093819 0,03813421 ! protein targeting to membrane GO:0006612 75 36 0,000 0,03093819 0,03811498 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03093819 0,03809577 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,03093819 0,03807658 ! aerobic respiration GO:0009060 56 36 0,000 0,03093819 0,03805741 ! cytokine production GO:0001816 68 36 0,000 0,03093819 0,03803825 ! embryonic organ development GO:0048568 67 36 0,000 0,03093819 0,03801912 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03093819 0,038 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,03093819 0,03798091 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,03178423 0,03899993 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,03178423 0,03898035 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,03178423 0,0389608 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,03178423 0,03894126 ! sister chromatid segregation GO:0000819 65 37 0,000 0,03178423 0,03892174 ! odontogenesis GO:0042476 74 37 0,000 0,03178423 0,03890224 ! actomyosin structure organization GO:0031032 68 37 0,000 0,03178423 0,03888276 ! cell junction organization GO:0034330 96 37 0,000 0,03178423 0,0388633 ! tissue remodeling GO:0048771 78 37 0,000 0,03178423 0,03884386 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,03178423 0,03882443 ! female gonad development GO:0008585 71 37 0,000 0,03178423 0,03880503 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,03178423 0,03878565 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,03178423 0,03876628 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,03178423 0,03874694 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,03178423 0,03872761 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03262954 0,03973778 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03262954 0,03971798 ! organic anion transport GO:0015711 82 38 0,000 0,03262954 0,0396982 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03262954 0,03967844 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03262954 0,0396587 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03262954 0,03963897 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03262954 0,03961927 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03262954 0,03959959 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,03262954 0,03957993 ! regulation of protein stability GO:0031647 77 38 0,000 0,03262954 0,03956029 ! spermatid development GO:0007286 69 38 0,000 0,03262954 0,03954066 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03262954 0,03952106 ! pigment metabolic process GO:0042440 87 38 0,000 0,03262954 0,03950148 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03262954 0,03948191 ! neural tube formation GO:0001841 79 38 0,000 0,03262954 0,03946236 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03347415 0,0404638 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03347415 0,04044379 ! negative regulation of binding GO:0051100 71 39 0,000 0,03347415 0,0404238 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03347415 0,04040383 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03347415 0,04038387 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03347415 0,04036394 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03347415 0,04034403 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03347415 0,04032413 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03347415 0,04030426 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03347415 0,04028441 ! glucan metabolic process GO:0044042 64 39 0,000 0,03347415 0,04026457 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03431804 0,04125933 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03431804 0,04123904 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03431804 0,04121876 ! learning GO:0007612 82 40 0,000 0,03431804 0,04119851 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03431804 0,04117827 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,03431804 0,04115806 ! lipid homeostasis GO:0055088 75 40 0,000 0,03431804 0,04113786 ! mismatch repair GO:0006298 58 40 0,000 0,03431804 0,04111769 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03431804 0,04109753 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03431804 0,0410774 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,03431804 0,04105728 ! RNA export from nucleus GO:0006405 61 41 0,000 0,03516121 0,04204545 ! mRNA catabolic process GO:0006402 79 41 0,000 0,03516121 0,04202488 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,03516121 0,04200433 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,03516121 0,0419838 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,03516121 0,04196329 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,03516121 0,0419428 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,03516121 0,04192233 ! gliogenesis GO:0042063 91 41 0,000 0,03516121 0,04190188 ! feeding behavior GO:0007631 69 41 0,000 0,03516121 0,04188145 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,03516121 0,04186104 ! mesenchymal cell development GO:0014031 94 41 0,000 0,03516121 0,04184065 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,03516121 0,04182028 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,03516121 0,04179992 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,03516121 0,04177959 ! spermatid differentiation GO:0048515 73 41 0,000 0,03516121 0,04175928 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,03516121 0,04173899 ! RNA modification GO:0009451 64 41 0,000 0,03516121 0,04171872 ! ear morphogenesis GO:0042471 64 42 0,000 0,03600368 0,04269757 ! organic ether metabolic process GO:0018904 59 42 0,000 0,03600368 0,04267685 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,03600368 0,04265615 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,03600368 0,04263548 ! T cell differentiation GO:0030217 93 42 0,000 0,03600368 0,04261482 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,03600368 0,04259418 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,03600368 0,04257357 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,03600368 0,04255297 ! regulation of protein secretion GO:0050708 77 42 0,000 0,03600368 0,04253239 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,03600368 0,04251183 ! cytokinesis GO:0000910 84 42 0,000 0,03600368 0,0424913 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,03600368 0,04247078 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,03684543 0,04344275 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,03684543 0,0434218 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,03684543 0,04340086 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,03684543 0,04337995 ! regulation of tube size GO:0035150 76 43 0,000 0,03684543 0,04335905 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,03684543 0,04333817 ! glucose transport GO:0015758 66 43 0,000 0,03684543 0,04331732 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,03684543 0,04329648 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,03684543 0,04327567 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,03684543 0,04325487 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,03684543 0,0432341 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,03684543 0,04321334 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,03684543 0,0431926 ! segmentation GO:0035282 78 43 0,000 0,03684543 0,04317189 ! ion transmembrane transport GO:0034220 79 43 0,000 0,03684543 0,04315119 ! neuron migration GO:0001764 85 43 0,000 0,03684543 0,04313052 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,03684543 0,04310986 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,03768647 0,04407279 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,03768647 0,0440517 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,03768647 0,04403063 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,03768647 0,04400958 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,03768647 0,04398856 ! hexose transport GO:0008645 68 44 0,000 0,03768647 0,04396755 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,03768647 0,04394656 ! striated muscle contraction GO:0006941 85 44 0,000 0,03768647 0,0439256 ! phagocytosis GO:0006909 105 44 0,000 0,03768647 0,04390465 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,03768647 0,04388372 ! double-strand break repair GO:0006302 85 44 0,000 0,03768647 0,04386282 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0385268 0,04481951 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,0385268 0,04479818 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,0385268 0,04477687 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0385268 0,04475558 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,0385268 0,0447343 ! biopolymer methylation GO:0043414 91 45 0,000 0,0385268 0,04471305 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,0385268 0,04469182 ! female gamete generation GO:0007292 71 45 0,000 0,0385268 0,04467061 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0385268 0,04464942 ! polyol metabolic process GO:0019751 77 45 0,000 0,0385268 0,04462825 ! developmental growth GO:0048589 88 45 0,000 0,0385268 0,0446071 ! maintenance of location in cell GO:0051651 101 45 0,000 0,0385268 0,04458597 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,03936642 0,04553606 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,03936642 0,04551451 ! glycolysis GO:0006096 71 46 0,000 0,03936642 0,04549298 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,03936642 0,04547147 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,03936642 0,04544998 ! leukocyte migration GO:0050900 75 46 0,000 0,03936642 0,04542852 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,03936642 0,04540707 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,03936642 0,04538564 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,03936642 0,04536423 ! pigmentation GO:0043473 103 46 0,000 0,03936642 0,04534284 ! cell growth GO:0016049 90 46 0,000 0,03936642 0,04532147 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,03936642 0,04530013 ! neural tube development GO:0021915 91 47 0,000 0,04020533 0,0462437 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,04020533 0,04622194 ! response to insulin stimulus GO:0032868 98 47 0,000 0,04020533 0,0462002 ! positive regulation of defense response GO:0031349 88 48 0,000 0,04104353 0,04714121 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,04104353 0,04711906 ! mitochondrial transport GO:0006839 94 48 0,000 0,04104353 0,04709692 ! cellular component disassembly GO:0022411 89 48 0,000 0,04104353 0,04707481 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,04104353 0,04705272 ! endosome transport GO:0016197 127 48 0,000 0,04104353 0,04703065 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,04104353 0,0470086 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,04104353 0,04698657 ! male sex differentiation GO:0046661 93 48 0,000 0,04104353 0,04696457 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,04104353 0,04694258 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,04104353 0,04692061 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,04104353 0,04689867 ! methylation GO:0032259 97 48 0,000 0,04104353 0,04687674 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,04188103 0,04781091 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,04188103 0,04778858 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,04188103 0,04776627 ! JNK cascade GO:0007254 106 49 0,000 0,04188103 0,04774398 ! protein homooligomerization GO:0051260 84 49 0,000 0,04188103 0,04772171 ! regulation of action potential GO:0001508 102 50 0,000 0,04271781 0,0486525 ! regulation of ion transport GO:0043269 86 50 0,000 0,04271781 0,04862983 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,04271781 0,04860718 ! endocrine system development GO:0035270 109 50 0,000 0,04271781 0,04858455 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,04271781 0,04856194 ! activation of caspase activity GO:0006919 95 50 0,000 0,04271781 0,04853935 ! regulation of ossification GO:0030278 123 50 0,000 0,04271781 0,04851679 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,04271781 0,04849424 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,04271781 0,04847172 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,04271781 0,04844922 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,04271781 0,04842673 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,04271781 0,04840427 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,04355389 0,04932877 ! viral infectious cycle GO:0019058 104 51 0,000 0,04355389 0,04930591 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,04355389 0,04928307 ! peptide metabolic process GO:0006518 80 51 0,000 0,04355389 0,04926025 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,04355389 0,04923746 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,04355389 0,04921469 ! positive regulation of binding GO:0051099 88 52 0,000 0,04438926 0,05013544 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,04438926 0,05011227 ! Notch signaling pathway GO:0007219 111 52 0,000 0,04438926 0,05008913 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,04438926 0,050066 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,04438926 0,0500429 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,04438926 0,05001982 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,04438926 0,04999676 ! excretion GO:0007588 87 52 0,000 0,04438926 0,04997372 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,04438926 0,0499507 ! histone modification GO:0016570 104 52 0,000 0,04438926 0,0499277 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,04438926 0,04990472 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,04438926 0,04988177 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,04438926 0,04985883 ! amino acid activation GO:0043038 98 52 0,000 0,04438926 0,04983592 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,04522393 0,05074968 ! positive regulation of growth GO:0045927 96 53 0,000 0,04522393 0,05072638 ! inner ear development GO:0048839 89 53 0,000 0,04522393 0,0507031 ! chromatin remodeling GO:0006338 122 53 0,000 0,04522393 0,05067984 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,04522393 0,0506566 ! vesicle organization GO:0016050 127 53 0,000 0,04522393 0,05063339 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,04522393 0,05061019 ! cartilage development GO:0051216 99 53 0,000 0,04522393 0,05058702 ! synapse organization GO:0050808 102 53 0,000 0,04522393 0,05056387 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,04605788 0,05147274 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,04605788 0,05144921 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,04605788 0,05142569 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,04605788 0,0514022 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,04605788 0,05137873 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,04605788 0,05135528 ! membrane fusion GO:0006944 122 54 0,000 0,04605788 0,05133185 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,04605788 0,05130844 ! covalent chromatin modification GO:0016569 115 54 0,000 0,04605788 0,05128506 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,04605788 0,05126169 ! regulation of cell shape GO:0008360 142 54 0,000 0,04605788 0,05123835 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,04605788 0,05121503 ! RNA catabolic process GO:0006401 103 55 0,000 0,04689114 0,05211786 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,04689114 0,05209416 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,04689114 0,05207048 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,04689114 0,05204682 ! cell recognition GO:0008037 98 55 0,000 0,04689114 0,05202319 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,04689114 0,05199957 ! cell maturation GO:0048469 107 55 0,000 0,04689114 0,05197598 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,04689114 0,05195241 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,04689114 0,05192885 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,04772369 0,0528269 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,04772369 0,05280298 ! glucose catabolic process GO:0006007 88 56 0,000 0,04772369 0,05277907 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,04772369 0,05275519 ! regulation of DNA replication GO:0006275 105 56 0,000 0,04772369 0,05273133 ! RNA elongation GO:0006354 90 56 0,000 0,04772369 0,05270749 ! chloride transport GO:0006821 102 57 0,000 0,04855554 0,05360198 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,04855554 0,05357777 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,04855554 0,05355358 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,04855554 0,05352941 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,04855554 0,05350527 ! heart morphogenesis GO:0003007 105 57 0,000 0,04855554 0,05348114 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,04855554 0,05345704 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,04855554 0,05343296 ! regulation of actin filament length GO:0030832 118 58 0,000 0,04938668 0,05432312 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,04938668 0,05429868 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,04938668 0,05427425 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,04938668 0,05424985 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,04938668 0,05422546 ! aging GO:0007568 112 58 0,000 0,04938668 0,0542011 ! gastrulation GO:0007369 122 58 0,000 0,04938668 0,05417677 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,04938668 0,05415245 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,04938668 0,05412815 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,04938668 0,05410388 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,04938668 0,05407963 ! maintenance of location GO:0051235 124 58 0,000 0,04938668 0,0540554 ! nuclear export GO:0051168 110 59 0,000 0,05021712 0,05493973 ! establishment of organelle localization GO:0051656 122 59 0,000 0,05021712 0,05491514 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,05104686 0,05579753 ! lipid modification GO:0030258 112 60 0,000 0,05104686 0,05577257 ! DNA catabolic process GO:0006308 94 60 0,000 0,05104686 0,05574764 ! regulation of endocytosis GO:0030100 104 60 0,000 0,05104686 0,05572273 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,05104686 0,05569784 ! adult behavior GO:0030534 104 60 0,000 0,05104686 0,05567298 ! kidney development GO:0001822 133 60 0,000 0,05104686 0,05564814 ! positive regulation of secretion GO:0051047 110 61 0,000 0,0518759 0,05652668 ! regulation of cellular component size GO:0032535 125 61 0,000 0,0518759 0,05650148 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,0518759 0,0564763 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,0518759 0,05645114 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,0518759 0,05642601 ! regulation of heart contraction GO:0008016 123 61 0,000 0,0518759 0,0564009 ! camera-type eye development GO:0043010 126 61 0,000 0,0518759 0,05637581 ! proton transport GO:0015992 117 61 0,000 0,0518759 0,05635074 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,0518759 0,05632569 ! viral reproductive process GO:0022415 132 62 0,000 0,05270423 0,05719966 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,05270423 0,05717426 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,05270423 0,05714888 ! tRNA processing GO:0008033 102 62 0,000 0,05270423 0,05712353 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,05270423 0,0570982 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,05353187 0,05796913 ! regulation of mitosis GO:0007088 112 63 0,000 0,05353187 0,05794344 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,05353187 0,05791778 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,05353187 0,05789214 ! hydrogen transport GO:0006818 121 64 0,000 0,0543588 0,05876042 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,0543588 0,05873443 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,0543588 0,05870847 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,0543588 0,05868253 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,0543588 0,05865661 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,05518504 0,05952188 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,05518504 0,05949561 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,05518504 0,05946937 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,05518504 0,05944314 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,05518504 0,05941695 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,05518504 0,05939077 ! ear development GO:0043583 114 66 0,000 0,05601058 0,06025268 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,05601058 0,06022616 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,05601058 0,06019967 ! gonad development GO:0008406 115 66 0,000 0,05601058 0,06017319 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,05601058 0,06014674 ! activation of MAPK activity GO:0000187 124 67 0,000 0,05683542 0,06100568 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,05683542 0,06097889 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,05683542 0,06095212 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,05683542 0,06092537 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,05683542 0,06089865 ! secondary metabolic process GO:0019748 125 67 0,000 0,05683542 0,06087195 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,05683542 0,06084528 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,05765956 0,06170053 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,05765956 0,06167351 ! hexose catabolic process GO:0019320 113 68 0,000 0,05765956 0,06164652 ! extracellular matrix organization GO:0030198 146 68 0,000 0,05765956 0,06161956 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,05765956 0,06159261 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,05765956 0,06156569 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,05765956 0,0615388 ! viral reproduction GO:0016032 142 68 0,000 0,05765956 0,06151192 ! regulation of lipase activity GO:0060191 137 68 0,000 0,05765956 0,06148507 ! adaptive immune response GO:0002250 126 68 0,000 0,05765956 0,06145825 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,05765956 0,06143145 ! cell projection assembly GO:0030031 138 68 0,000 0,05765956 0,06140467 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,05848301 0,06225446 ! lung development GO:0030324 165 69 0,000 0,05848301 0,06222734 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,05848301 0,06220025 ! urogenital system development GO:0001655 149 69 0,000 0,05848301 0,06217319 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,05848301 0,06214614 ! developmental maturation GO:0021700 128 69 0,000 0,05848301 0,06211912 ! single fertilization GO:0007338 83 69 0,000 0,05848301 0,06209213 ! cell redox homeostasis GO:0045454 114 70 0,000 0,05930575 0,0629383 ! germ cell development GO:0007281 133 70 0,000 0,05930575 0,06291097 ! activation of immune response GO:0002253 120 70 0,000 0,05930575 0,06288366 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,05930575 0,06285638 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,06012781 0,06370002 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,06012781 0,0636724 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,06012781 0,06364482 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,06012781 0,06361725 ! appendage morphogenesis GO:0035107 150 72 0,000 0,06094917 0,06445836 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,06094917 0,06443047 ! respiratory tube development GO:0030323 171 72 0,000 0,06094917 0,0644026 ! actin filament organization GO:0007015 167 72 0,000 0,06094917 0,06437476 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,06094917 0,06434694 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,06094917 0,06431914 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,06094917 0,06429137 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,06094917 0,06426362 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,06094917 0,0642359 ! appendage development GO:0048736 151 73 0,000 0,06176983 0,06507274 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,06176983 0,0650447 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,06176983 0,06501667 ! regulation of immune effector process GO:0002697 156 73 0,000 0,06176983 0,06498867 ! acute inflammatory response GO:0002526 118 74 0,000 0,0625898 0,06582302 ! amino acid transport GO:0006865 148 74 0,000 0,0625898 0,0657947 ! regulation of caspase activity GO:0043281 136 74 0,000 0,0625898 0,0657664 ! respiratory system development GO:0060541 175 74 0,000 0,0625898 0,06573813 ! organelle localization GO:0051640 155 74 0,000 0,0625898 0,06570987 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,06340907 0,0665414 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,06340907 0,06651283 ! reproductive structure development GO:0048608 131 75 0,000 0,06340907 0,06648428 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,06340907 0,06645576 ! eye development GO:0001654 155 75 0,000 0,06340907 0,06642726 ! axon guidance GO:0007411 162 75 0,000 0,06340907 0,06639879 ! rhythmic process GO:0048511 142 75 0,000 0,06340907 0,06637034 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,06422766 0,06719836 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,06422766 0,06716959 ! learning or memory GO:0007611 161 76 0,000 0,06422766 0,06714085 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,06422766 0,06711213 ! regulation of blood pressure GO:0008217 134 76 0,000 0,06422766 0,06708344 ! amine catabolic process GO:0009310 136 77 0,000 0,06504555 0,06790866 ! neurotransmitter transport GO:0006836 142 77 0,000 0,06504555 0,06787966 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,06504555 0,06785067 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,06504555 0,06782171 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,06504555 0,06779278 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,06504555 0,06776387 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,06504555 0,06773498 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,06504555 0,06770612 ! regulation of catabolic process GO:0009894 173 77 0,000 0,06504555 0,06767729 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,06586275 0,06849838 ! antigen processing and presentation GO:0019882 117 78 0,000 0,06586275 0,06846923 ! fertilization GO:0009566 99 78 0,000 0,06586275 0,06844011 ! blood coagulation GO:0007596 151 79 0,000 0,06667925 0,06925911 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,06667925 0,06922967 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,06667925 0,06920026 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,06667925 0,06917088 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,06667925 0,06914152 ! protein oligomerization GO:0051259 149 79 0,000 0,06667925 0,06911218 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,06667925 0,06908287 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,06749507 0,06989846 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,06749507 0,06986884 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,06749507 0,06983925 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,06749507 0,06980968 ! muscle cell differentiation GO:0042692 178 81 0,000 0,0683102 0,07062286 ! response to hypoxia GO:0001666 178 81 0,000 0,0683102 0,07059298 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,0683102 0,07056313 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,06912464 0,07137425 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,06912464 0,0713441 ! protein import into nucleus GO:0006606 174 82 0,000 0,06912464 0,07131397 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,06993838 0,07212304 ! exocytosis GO:0006887 153 83 0,000 0,06993838 0,0720926 ! response to drug GO:0042493 149 83 0,000 0,06993838 0,0720622 ! response to oxygen levels GO:0070482 183 83 0,000 0,06993838 0,07203182 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,06993838 0,07200146 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,06993838 0,07197113 ! nuclear import GO:0051170 177 83 0,000 0,06993838 0,07194083 ! inorganic anion transport GO:0015698 156 83 0,000 0,06993838 0,07191055 ! T cell activation GO:0042110 189 84 0,000 0,07075144 0,07271593 ! response to nutrient GO:0007584 135 84 0,000 0,07075144 0,07268536 ! digestion GO:0007586 130 84 0,000 0,07075144 0,0726548 ! regulation of ligase activity GO:0051340 147 84 0,000 0,07075144 0,07262428 ! hemostasis GO:0007599 165 85 0,000 0,07156381 0,0734273 ! negative regulation of transport GO:0051051 164 85 0,000 0,07156381 0,07339647 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,07156381 0,07336567 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,07156381 0,0733349 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,07156381 0,07330415 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,07156381 0,07327343 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,07156381 0,07324273 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,0723755 0,07404244 ! regulation of lyase activity GO:0051339 169 86 0,000 0,0723755 0,07401145 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,0731865 0,07480946 ! mitochondrion organization GO:0007005 159 87 0,000 0,0731865 0,07477817 ! alcohol catabolic process GO:0046164 142 87 0,000 0,0731865 0,07474691 ! nucleosome assembly GO:0006334 126 87 0,000 0,0731865 0,07471568 ! regulation of protein transport GO:0051223 165 87 0,000 0,0731865 0,07468447 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,07399681 0,07547983 ! amine biosynthetic process GO:0009309 146 88 0,000 0,07399681 0,07544833 ! sensory perception of smell GO:0007608 117 88 0,000 0,07399681 0,07541686 ! chromatin assembly GO:0031497 128 88 0,000 0,07399681 0,07538541 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,07399681 0,07535398 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,07480643 0,07614672 ! regulation of DNA binding GO:0051101 167 89 0,000 0,07480643 0,076115 ! tube morphogenesis GO:0035239 194 89 0,000 0,07480643 0,07608331 ! cellular defense response GO:0006968 123 89 0,000 0,07480643 0,07605165 ! protein localization in nucleus GO:0034504 192 89 0,000 0,07480643 0,07602002 ! regulation of neurological system process GO:0031644 175 89 0,000 0,07480643 0,07598841 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,07561538 0,07677821 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,07561538 0,07674631 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,07642363 0,07753444 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,07642363 0,07750226 ! gland development GO:0048732 220 91 0,000 0,07642363 0,0774701 ! defense response to bacterium GO:0042742 112 91 0,000 0,07642363 0,07743796 ! bone development GO:0060348 206 92 0,000 0,0772312 0,07822381 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,0772312 0,07819139 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,0772312 0,078159 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,07803809 0,07894288 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,07803809 0,07891021 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,07803809 0,07887756 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,07803809 0,07884494 ! vitamin metabolic process GO:0006766 153 93 0,000 0,07803809 0,07881235 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,0788443 0,07959365 ! female pregnancy GO:0007565 166 94 0,000 0,0788443 0,07956077 ! sterol metabolic process GO:0016125 166 94 0,000 0,0788443 0,07952792 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,0788443 0,0794951 ! regulation of membrane potential GO:0042391 179 94 0,000 0,0788443 0,0794623 ! regulation of defense response GO:0031347 171 95 0,000 0,07964982 0,08024104 ! nucleosome organization GO:0034728 143 95 0,000 0,07964982 0,08020796 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,07964982 0,08017492 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,07964982 0,08014189 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,07964982 0,0801089 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,07964982 0,08007593 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,07964982 0,08004299 ! sex differentiation GO:0007548 171 96 0,000 0,08045467 0,08081856 ! regulation of T cell activation GO:0050863 175 96 0,000 0,08045467 0,08078535 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,08125883 0,08155929 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,08125883 0,0815258 ! transcription initiation GO:0006352 171 97 0,000 0,08125883 0,08149233 ! regulation of protein localization GO:0032880 188 97 0,000 0,08125883 0,08145889 ! forebrain development GO:0030900 210 98 0,000 0,08206231 0,08223061 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,08206231 0,08219689 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,08366723 0,0837701 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,08366723 0,08373578 ! positive regulation of immune response GO:0050778 175 100 0,000 0,08366723 0,08370149 ! hormone metabolic process GO:0042445 171 100 0,000 0,08366723 0,08366723