pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/6628-8-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spliceosomal snRNP biogenesis GO:0000387 38 27 3,000 1,91E-09 4,531E-06 ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 2,000 7,625E-09 9,047E-06 ! nucleoside diphosphate metabolic process GO:0009132 9 8 2,000 1,219E-08 9,646E-06 ! deoxyribonucleotide metabolic process GO:0009262 29 22 2,000 3,336E-07 1,979E-04 ! regulation of translational initiation GO:0006446 70 46 2,000 3,259E-06 1,547E-03 ! protein oligomerization GO:0051259 109 66 2,000 9,749E-06 3,856E-03 ! response to heat GO:0009408 43 30 1,000 1,698E-04 0,05756633 ! spliceosome assembly GO:0000245 65 36 1,000 2,454E-04 0,07278921 ! response to temperature stimulus GO:0009266 66 49 1,000 4,559E-04 0,12019865 ! ribonucleoprotein complex assembly GO:0022618 90 54 1,000 5,537E-04 0,13139349 ! response to unfolded protein GO:0006986 113 80 1,000 1,211E-03 0,26125594 ! response to protein stimulus GO:0051789 127 85 1,000 1,366E-03 0,27005883 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,264E-03 0,59587133 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 3,264E-03 0,55330909 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 3,264E-03 0,51642182 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 3,264E-03 0,48414546 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,264E-03 0,45566631 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 3,264E-03 0,43035152 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,264E-03 0,40770144 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 3,264E-03 0,38731636 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,264E-03 0,36887273 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 3,264E-03 0,35210579 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 3,264E-03 0,33679684 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,264E-03 0,32276364 ! response to oxygen radical GO:0000305 11 5 0,000 3,264E-03 0,30985309 ! negative regulation of bone resorption GO:0045779 11 5 0,000 3,264E-03 0,29793567 ! myoblast cell fate commitment GO:0048625 8 5 0,000 3,264E-03 0,28690101 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,264E-03 0,27665455 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 3,264E-03 0,26711473 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,264E-03 0,25821091 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 3,264E-03 0,24988153 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 3,264E-03 0,24207273 ! female meiosis GO:0007143 8 5 0,000 3,264E-03 0,23473719 ! nose development GO:0043584 10 5 0,000 3,264E-03 0,22783316 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 3,264E-03 0,22132364 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 3,264E-03 0,21517576 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 3,264E-03 0,2093602 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 3,264E-03 0,20385072 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 3,264E-03 0,19862378 ! cobalt ion transport GO:0006824 9 5 0,000 3,264E-03 0,19365818 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,264E-03 0,18893481 ! SMAD protein complex assembly GO:0007183 10 5 0,000 3,264E-03 0,18443636 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 3,264E-03 0,18014715 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,264E-03 0,17605289 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,264E-03 0,17214061 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,264E-03 0,16839842 ! adaptation of signaling pathway GO:0022401 9 5 0,000 3,264E-03 0,16481547 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 3,264E-03 0,16138182 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,264E-03 0,15808831 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 3,264E-03 0,15492655 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,264E-03 0,15188877 ! negative regulation of histone modification GO:0031057 7 5 0,000 3,264E-03 0,14896783 ! malate metabolic process GO:0006108 8 5 0,000 3,264E-03 0,14615712 ! positive regulation of histone modification GO:0031058 6 5 0,000 3,264E-03 0,14345051 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 3,264E-03 0,14084231 ! clathrin coat assembly GO:0048268 11 5 0,000 3,264E-03 0,13832727 ! Notch receptor processing GO:0007220 8 5 0,000 3,264E-03 0,13590048 ! phototransduction, visible light GO:0007603 7 5 0,000 3,264E-03 0,13355737 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,264E-03 0,13129368 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,264E-03 0,12910545 ! mating behavior GO:0007617 6 5 0,000 3,264E-03 0,12698897 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,264E-03 0,12494076 ! copulation GO:0007620 8 5 0,000 3,264E-03 0,12295758 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,264E-03 0,12103636 ! embryonic hemopoiesis GO:0035162 13 5 0,000 3,264E-03 0,11917427 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,264E-03 0,1173686 ! apoptotic cell clearance GO:0043277 14 5 0,000 3,264E-03 0,11561683 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 3,264E-03 0,11391658 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,264E-03 0,11226561 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 3,264E-03 0,11066182 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 3,264E-03 0,1091032 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 3,264E-03 0,10758788 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 3,264E-03 0,10611407 ! response to axon injury GO:0048678 8 5 0,000 3,264E-03 0,1046801 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,264E-03 0,10328436 ! response to protozoan GO:0001562 10 5 0,000 3,264E-03 0,10192536 ! negative regulation of heart contraction GO:0045822 12 5 0,000 3,264E-03 0,10060165 ! lymph vessel development GO:0001945 8 5 0,000 3,264E-03 0,09931189 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 3,264E-03 0,09805478 ! endochondral ossification GO:0001958 13 5 0,000 3,264E-03 0,09682909 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,264E-03 0,09563367 ! single strand break repair GO:0000012 5 5 0,000 3,264E-03 0,09446741 ! parathyroid gland development GO:0060017 8 5 0,000 3,264E-03 0,09332924 ! anagen GO:0042640 7 5 0,000 3,264E-03 0,09221818 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,264E-03 0,09113326 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,264E-03 0,09007357 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,264E-03 0,08903824 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 3,264E-03 0,08802645 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 3,264E-03 0,08703739 ! smooth muscle tissue development GO:0048745 14 5 0,000 3,264E-03 0,0860703 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,264E-03 0,08512448 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,264E-03 0,08419921 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,264E-03 0,08329384 ! cardiac muscle fiber development GO:0048739 8 5 0,000 3,264E-03 0,08240774 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,264E-03 0,08154029 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 3,264E-03 0,08069091 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,264E-03 0,07985904 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,264E-03 0,07904416 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 3,264E-03 0,07824573 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 3,264E-03 0,07746327 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 3,264E-03 0,07669631 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 3,264E-03 0,07594439 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 3,264E-03 0,07520706 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,264E-03 0,07448392 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 3,264E-03 0,07377455 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,264E-03 0,07307856 ! tyrosine catabolic process GO:0006572 7 5 0,000 3,264E-03 0,07239558 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,264E-03 0,07172525 ! proline biosynthetic process GO:0006561 6 5 0,000 3,264E-03 0,07106722 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,264E-03 0,07042116 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,264E-03 0,06978673 ! polyol catabolic process GO:0046174 7 5 0,000 3,264E-03 0,06916364 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 3,264E-03 0,06855157 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,264E-03 0,06795024 ! sister chromatid cohesion GO:0007062 10 5 0,000 3,264E-03 0,06735937 ! response to ATP GO:0033198 6 5 0,000 3,264E-03 0,06677868 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 3,264E-03 0,06620793 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 3,264E-03 0,06564684 ! neutrophil activation GO:0042119 6 5 0,000 3,264E-03 0,06509519 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,264E-03 0,06455273 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,264E-03 0,06401923 ! response to food GO:0032094 5 5 0,000 3,264E-03 0,06349449 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,264E-03 0,06297827 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 3,264E-03 0,06247038 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 3,264E-03 0,06197062 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,264E-03 0,06147879 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,264E-03 0,0609947 ! forebrain neuron development GO:0021884 7 5 0,000 3,264E-03 0,06051818 ! melanosome organization GO:0032438 7 5 0,000 3,264E-03 0,06004905 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,264E-03 0,05958713 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 3,264E-03 0,05913227 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,264E-03 0,0586843 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 3,264E-03 0,05824306 ! mesodermal cell fate determination GO:0007500 7 5 0,000 3,264E-03 0,05780841 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,264E-03 0,0573802 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 3,264E-03 0,05695829 ! nucleoside salvage GO:0043174 7 5 0,000 3,264E-03 0,05654253 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 3,264E-03 0,05613281 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 3,264E-03 0,05572897 ! negative regulation of platelet activation GO:0010544 8 5 0,000 3,264E-03 0,05533091 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,264E-03 0,05493849 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,264E-03 0,0545516 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 3,264E-03 0,05417012 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 3,264E-03 0,05379394 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,264E-03 0,05342295 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 3,264E-03 0,05305704 ! depyrimidination GO:0045008 8 5 0,000 3,264E-03 0,0526961 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,264E-03 0,05234005 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,264E-03 0,05198877 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 3,264E-03 0,05164218 ! neuronal ion channel clustering GO:0045161 8 5 0,000 3,264E-03 0,05130018 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,264E-03 0,05096268 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,264E-03 0,05062959 ! monocyte differentiation GO:0030224 7 5 0,000 3,264E-03 0,05030083 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 3,264E-03 0,04997631 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 3,264E-03 0,04965594 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,264E-03 0,04933966 ! response to UV-C GO:0010225 7 5 0,000 3,264E-03 0,04902739 ! protein targeting to vacuole GO:0006623 6 5 0,000 3,264E-03 0,04871904 ! activated T cell proliferation GO:0050798 7 5 0,000 3,264E-03 0,04841455 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 3,264E-03 0,04811383 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 3,264E-03 0,04781684 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,264E-03 0,04752348 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 3,264E-03 0,0472337 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 3,264E-03 0,04694744 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,264E-03 0,04666462 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 3,264E-03 0,04638519 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 3,264E-03 0,04610909 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 3,264E-03 0,04583626 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 3,264E-03 0,04556663 ! response to cadmium ion GO:0046686 8 5 0,000 3,264E-03 0,04530016 ! melanosome transport GO:0032402 8 5 0,000 3,264E-03 0,04503679 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 3,264E-03 0,04477646 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 3,264E-03 0,04451912 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,264E-03 0,04426473 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,264E-03 0,04401322 ! positive T cell selection GO:0043368 10 5 0,000 3,264E-03 0,04376456 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 3,264E-03 0,04351869 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 3,264E-03 0,04327557 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 3,264E-03 0,04303515 ! ribosomal subunit assembly GO:0042257 5 5 0,000 3,264E-03 0,04279739 ! base conversion or substitution editing GO:0016553 6 5 0,000 3,264E-03 0,04256224 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 3,264E-03 0,04232966 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 3,264E-03 0,0420996 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 3,264E-03 0,04187204 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 3,264E-03 0,04164692 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,264E-03 0,04142421 ! histone demethylation GO:0016577 10 5 0,000 3,264E-03 0,04120387 ! mitotic recombination GO:0006312 10 5 0,000 3,264E-03 0,04098586 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 3,264E-03 0,04077014 ! regulation of sterol transport GO:0032371 7 5 0,000 3,264E-03 0,04055669 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,264E-03 0,04034545 ! sympathetic nervous system development GO:0048485 13 5 0,000 3,264E-03 0,04013641 ! enteric nervous system development GO:0048484 9 5 0,000 3,264E-03 0,03992952 ! oxygen homeostasis GO:0032364 8 5 0,000 3,264E-03 0,03972476 ! establishment of planar polarity GO:0001736 7 5 0,000 3,264E-03 0,03952208 ! lymphocyte costimulation GO:0031294 12 5 0,000 3,264E-03 0,03932146 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 3,264E-03 0,03912287 ! transcription termination GO:0006353 8 5 0,000 3,264E-03 0,03892627 ! plasminogen activation GO:0031639 5 5 0,000 3,264E-03 0,03873164 ! B cell homeostasis GO:0001782 12 5 0,000 3,264E-03 0,03853894 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,264E-03 0,03834815 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,264E-03 0,03815925 ! regulation of hair follicle development GO:0051797 9 5 0,000 3,264E-03 0,03797219 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,264E-03 0,03778696 ! apical protein localization GO:0045176 8 5 0,000 3,264E-03 0,03760353 ! definitive hemopoiesis GO:0060216 5 5 0,000 3,264E-03 0,03742187 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 3,264E-03 0,03724196 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,264E-03 0,03706377 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 3,264E-03 0,03688727 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 3,264E-03 0,03671245 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,264E-03 0,03653928 ! regulation of centrosome duplication GO:0010824 6 5 0,000 3,264E-03 0,03636773 ! disaccharide metabolic process GO:0005984 9 5 0,000 3,264E-03 0,03619779 ! galactolipid metabolic process GO:0019374 8 5 0,000 3,264E-03 0,03602943 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,264E-03 0,03586263 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 3,264E-03 0,03569736 ! determination of adult lifespan GO:0008340 8 5 0,000 3,264E-03 0,03553361 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,264E-03 0,03537136 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 3,264E-03 0,03521058 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 3,264E-03 0,03505125 ! T cell activation during immune response GO:0002286 9 5 0,000 3,264E-03 0,03489337 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 3,264E-03 0,03473689 ! negative regulation of lipase activity GO:0060192 7 5 0,000 3,264E-03 0,03458182 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 3,264E-03 0,03442812 ! neural plate development GO:0001840 7 5 0,000 3,264E-03 0,03427578 ! regulation of sensory perception GO:0051931 6 5 0,000 3,264E-03 0,03412479 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 3,264E-03 0,03397512 ! regulation of histone acetylation GO:0035065 7 5 0,000 3,264E-03 0,03382676 ! sensory cilium assembly GO:0035058 6 5 0,000 3,264E-03 0,03367968 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 3,264E-03 0,03353388 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 3,264E-03 0,03338934 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,264E-03 0,03324604 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 3,264E-03 0,03310396 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 3,264E-03 0,03296309 ! receptor biosynthetic process GO:0032800 6 5 0,000 3,264E-03 0,03282342 ! penetration of zona pellucida GO:0007341 9 5 0,000 3,264E-03 0,03268493 ! drug metabolic process GO:0017144 5 5 0,000 3,264E-03 0,03254759 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,264E-03 0,03241141 ! organ regeneration GO:0031100 7 5 0,000 3,264E-03 0,03227636 ! carnitine metabolic process GO:0009437 5 5 0,000 3,264E-03 0,03214244 GO:0006577|betaine metabolic process, ! tRNA transcription GO:0009304 11 6 0,000 3,916E-03 0,03839995 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 3,916E-03 0,03824193 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,916E-03 0,0380852 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 3,916E-03 0,03792975 ! regulation of helicase activity GO:0051095 11 6 0,000 3,916E-03 0,03777556 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 3,916E-03 0,03762263 ! sleep GO:0030431 13 6 0,000 3,916E-03 0,03747092 ! positive regulation of axon extension GO:0045773 10 6 0,000 3,916E-03 0,03732044 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 3,916E-03 0,03717116 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 3,916E-03 0,03702306 ! forebrain regionalization GO:0021871 7 6 0,000 3,916E-03 0,03687615 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 3,916E-03 0,03673039 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 3,916E-03 0,03658578 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 3,916E-03 0,03644231 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 3,916E-03 0,03629996 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 3,916E-03 0,03615871 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 3,916E-03 0,03601856 ! neuron adhesion GO:0007158 9 6 0,000 3,916E-03 0,03587949 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 3,916E-03 0,0357415 ! signal peptide processing GO:0006465 8 6 0,000 3,916E-03 0,03560456 ! embryonic camera-type eye development GO:0031076 11 6 0,000 3,916E-03 0,03546866 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 3,916E-03 0,0353338 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 3,916E-03 0,03519996 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 3,916E-03 0,03506713 ! fibril organization GO:0043206 13 6 0,000 3,916E-03 0,0349353 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 3,916E-03 0,03480445 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 3,916E-03 0,03467459 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 3,916E-03 0,03454568 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 3,916E-03 0,03441774 ! protein refolding GO:0042026 13 6 0,000 3,916E-03 0,03429073 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 3,916E-03 0,03416467 ! rhythmic behavior GO:0007622 14 6 0,000 3,916E-03 0,03403952 ! glial cell fate commitment GO:0021781 17 6 0,000 3,916E-03 0,03391529 ! erythrocyte maturation GO:0043249 7 6 0,000 3,916E-03 0,03379196 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 3,916E-03 0,03366953 ! protein amino acid dealkylation GO:0008214 12 6 0,000 3,916E-03 0,03354797 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 3,916E-03 0,0334273 ! regulation of odontogenesis GO:0042481 8 6 0,000 3,916E-03 0,03330749 ! mechanosensory behavior GO:0007638 8 6 0,000 3,916E-03 0,03318853 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 3,916E-03 0,03307042 ! negative regulation of endocytosis GO:0045806 8 6 0,000 3,916E-03 0,03295315 ! response to interferon-gamma GO:0034341 12 6 0,000 3,916E-03 0,03283671 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 3,916E-03 0,03272109 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 3,916E-03 0,03260628 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 3,916E-03 0,03249227 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 3,916E-03 0,03237906 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 3,916E-03 0,03226663 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 3,916E-03 0,03215498 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 3,916E-03 0,0320441 ! cGMP-mediated signaling GO:0019934 11 6 0,000 3,916E-03 0,03193398 ! activation of MAPKKK activity GO:0000185 11 6 0,000 3,916E-03 0,03182462 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 3,916E-03 0,031716 ! protein lipoylation GO:0009249 10 6 0,000 3,916E-03 0,03160813 ! pigment granule organization GO:0048753 11 6 0,000 3,916E-03 0,03150098 ! drug transport GO:0015893 6 6 0,000 3,916E-03 0,03139456 ! transepithelial chloride transport GO:0030321 10 6 0,000 3,916E-03 0,03128885 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 3,916E-03 0,03118386 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 3,916E-03 0,03107956 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 3,916E-03 0,03097596 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 3,916E-03 0,03087305 ! glutamate catabolic process GO:0006538 11 6 0,000 3,916E-03 0,03077082 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 3,916E-03 0,03066927 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 3,916E-03 0,03056838 ! adenohypophysis development GO:0021984 10 6 0,000 3,916E-03 0,03046816 ! response to pH GO:0009268 10 6 0,000 3,916E-03 0,03036859 ! hyperosmotic response GO:0006972 9 6 0,000 3,916E-03 0,03026967 ! microtubule nucleation GO:0007020 10 6 0,000 3,916E-03 0,03017139 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 3,916E-03 0,03007375 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 3,916E-03 0,02997674 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 3,916E-03 0,02988035 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 3,916E-03 0,02978458 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 3,916E-03 0,02968942 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 3,916E-03 0,02959487 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 3,916E-03 0,02950092 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 3,916E-03 0,02940756 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 3,916E-03 0,02931479 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 3,916E-03 0,02922261 ! purine salvage GO:0043101 9 6 0,000 3,916E-03 0,029131 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,916E-03 0,02903997 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 3,916E-03 0,0289495 ! nucleoside transport GO:0015858 7 6 0,000 3,916E-03 0,02885959 ! organic alcohol transport GO:0015850 9 6 0,000 3,916E-03 0,02877024 ! T cell mediated immunity GO:0002456 12 6 0,000 3,916E-03 0,02868145 ! folic acid transport GO:0015884 11 6 0,000 3,916E-03 0,0285932 ! male sex determination GO:0030238 11 6 0,000 3,916E-03 0,02850549 ! carnitine transport GO:0015879 8 6 0,000 3,916E-03 0,02841831 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 3,916E-03 0,02833167 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,916E-03 0,02824556 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 3,916E-03 0,02815997 ! positive regulation of exocytosis GO:0045921 9 6 0,000 3,916E-03 0,02807489 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 3,916E-03 0,02799033 ! parturition GO:0007567 13 6 0,000 3,916E-03 0,02790627 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 3,916E-03 0,02782272 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 3,916E-03 0,02773967 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 3,916E-03 0,02765711 ! regulation of centrosome cycle GO:0046605 8 6 0,000 3,916E-03 0,02757504 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 3,916E-03 0,02749346 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 3,916E-03 0,02741236 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 3,916E-03 0,02733173 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 3,916E-03 0,02725158 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 3,916E-03 0,0271719 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 3,916E-03 0,02709268 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 3,916E-03 0,02701392 ! neural nucleus development GO:0048857 12 6 0,000 3,916E-03 0,02693562 ! forebrain morphogenesis GO:0048853 14 6 0,000 3,916E-03 0,02685777 ! hyaluronan metabolic process GO:0030212 7 6 0,000 3,916E-03 0,02678037 ! purine base biosynthetic process GO:0009113 14 6 0,000 3,916E-03 0,02670342 ! interaction with symbiont GO:0051702 9 6 0,000 3,916E-03 0,0266269 ! regulation of dendrite development GO:0050773 13 6 0,000 3,916E-03 0,02655083 ! anterograde axon cargo transport GO:0008089 9 6 0,000 3,916E-03 0,02647518 ! positive regulation of organ growth GO:0046622 7 6 0,000 3,916E-03 0,02639997 ! eating behavior GO:0042755 6 6 0,000 3,916E-03 0,02632518 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 3,916E-03 0,02625082 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 3,916E-03 0,02617687 ! response to copper ion GO:0046688 9 6 0,000 3,916E-03 0,02610334 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 3,916E-03 0,02603022 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 3,916E-03 0,02595751 ! establishment of melanosome localization GO:0032401 9 6 0,000 3,916E-03 0,02588521 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,916E-03 0,0258133 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 3,916E-03 0,0257418 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 3,916E-03 0,02567069 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,916E-03 0,02559997 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,916E-03 0,02552964 ! hair follicle maturation GO:0048820 8 6 0,000 3,916E-03 0,0254597 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 3,916E-03 0,02539013 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 3,916E-03 0,02532095 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 3,916E-03 0,02525214 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 3,916E-03 0,02518371 ! rhombomere development GO:0021546 6 6 0,000 3,916E-03 0,02511565 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 3,916E-03 0,02504795 ! G2 phase GO:0051319 15 6 0,000 3,916E-03 0,02498062 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 3,916E-03 0,02491364 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 3,916E-03 0,02484703 ! muscle cell proliferation GO:0033002 9 6 0,000 3,916E-03 0,02478077 ! membrane to membrane docking GO:0022614 12 6 0,000 3,916E-03 0,02471486 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 3,916E-03 0,02464931 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 3,916E-03 0,0245841 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 3,916E-03 0,02451923 ! receptor internalization GO:0031623 9 6 0,000 3,916E-03 0,02445471 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 3,916E-03 0,02439052 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 3,916E-03 0,02432667 ! coenzyme A metabolic process GO:0015936 9 6 0,000 3,916E-03 0,02426316 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 3,916E-03 0,02419997 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 3,916E-03 0,02413711 ! peptidyl-histidine modification GO:0018202 10 6 0,000 3,916E-03 0,02407458 ! axonal fasciculation GO:0007413 10 6 0,000 3,916E-03 0,02401237 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 3,916E-03 0,02395049 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 3,916E-03 0,02388892 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 3,916E-03 0,02382766 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 3,916E-03 0,02376672 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,916E-03 0,02370609 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 3,916E-03 0,02364577 ! progesterone metabolic process GO:0042448 8 6 0,000 3,916E-03 0,02358576 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 3,916E-03 0,02352605 ! glycolipid catabolic process GO:0019377 14 6 0,000 3,916E-03 0,02346664 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 3,916E-03 0,02340753 ! negative regulation of axon extension GO:0030517 13 6 0,000 3,916E-03 0,02334872 ! removal of superoxide radicals GO:0019430 10 6 0,000 3,916E-03 0,0232902 ! triglyceride catabolic process GO:0019433 8 6 0,000 3,916E-03 0,02323197 ! protein modification by small protein removal GO:0070646 10 6 0,000 3,916E-03 0,02317404 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 3,916E-03 0,02311639 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 3,916E-03 0,02305903 ! glial cell migration GO:0008347 11 6 0,000 3,916E-03 0,02300195 ! blastocyst growth GO:0001832 17 6 0,000 3,916E-03 0,02294516 ! pigment granule transport GO:0051904 12 6 0,000 3,916E-03 0,02288864 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 3,916E-03 0,02283241 ! cerebellar cortex formation GO:0021697 9 6 0,000 3,916E-03 0,02277644 ! catecholamine transport GO:0051937 7 6 0,000 3,916E-03 0,02272076 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 3,916E-03 0,02266534 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 3,916E-03 0,02261019 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,916E-03 0,02255531 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 3,916E-03 0,0225007 ! spindle assembly GO:0051225 6 6 0,000 3,916E-03 0,02244635 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 3,916E-03 0,02239226 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 3,916E-03 0,02233844 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 3,916E-03 0,02228487 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 3,916E-03 0,02223155 ! NAD biosynthetic process GO:0009435 9 6 0,000 3,916E-03 0,02217849 ! positive regulation of coagulation GO:0050820 11 6 0,000 3,916E-03 0,02212569 ! cellular anion homeostasis GO:0030002 9 6 0,000 3,916E-03 0,02207313 GO:0055081|anion homeostasis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 4,567E-03 0,02568322 ! behavioral response to cocaine GO:0048148 13 7 0,000 4,567E-03 0,0256225 ! autophagic vacuole formation GO:0000045 12 7 0,000 4,567E-03 0,02556207 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 4,567E-03 0,02550192 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 4,567E-03 0,02544206 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 4,567E-03 0,02538248 ! prostate gland development GO:0030850 11 7 0,000 4,567E-03 0,02532317 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 4,567E-03 0,02526414 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 4,567E-03 0,02520539 ! synaptonemal complex assembly GO:0007130 11 7 0,000 4,567E-03 0,02514691 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 4,567E-03 0,0250887 ! male meiosis GO:0007140 10 7 0,000 4,567E-03 0,02503076 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,567E-03 0,02497308 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 4,567E-03 0,02491567 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 4,567E-03 0,02485853 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 4,567E-03 0,02480164 ! oligopeptide transport GO:0006857 11 7 0,000 4,567E-03 0,02474502 ! protein amino acid sulfation GO:0006477 9 7 0,000 4,567E-03 0,02468865 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 4,567E-03 0,02463254 ! establishment of tissue polarity GO:0007164 10 7 0,000 4,567E-03 0,02457668 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 4,567E-03 0,02452108 ! RNA methylation GO:0001510 11 7 0,000 4,567E-03 0,02446573 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 4,567E-03 0,02441062 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 4,567E-03 0,02435577 ! pericardium development GO:0060039 9 7 0,000 4,567E-03 0,02430116 ! macrophage chemotaxis GO:0048246 10 7 0,000 4,567E-03 0,02424679 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 4,567E-03 0,02419267 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,567E-03 0,02413879 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 4,567E-03 0,02408515 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 4,567E-03 0,02403175 ! cerebral cortex cell migration GO:0021795 11 7 0,000 4,567E-03 0,02397858 ! opsonization GO:0008228 9 7 0,000 4,567E-03 0,02392565 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 4,567E-03 0,02387295 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 4,567E-03 0,02382048 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 4,567E-03 0,02376824 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 4,567E-03 0,02371623 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 4,567E-03 0,02366445 ! chemosensory behavior GO:0007635 9 7 0,000 4,567E-03 0,02361289 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 4,567E-03 0,02356156 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 4,567E-03 0,02351045 ! leukocyte degranulation GO:0043299 11 7 0,000 4,567E-03 0,02345956 ! positive regulation of glycolysis GO:0045821 13 7 0,000 4,567E-03 0,02340889 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 4,567E-03 0,02335844 ! positive regulation of heart rate GO:0010460 11 7 0,000 4,567E-03 0,02330821 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,567E-03 0,02325819 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 4,567E-03 0,02320839 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 4,567E-03 0,0231588 ! spinal cord patterning GO:0021511 9 7 0,000 4,567E-03 0,02310942 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 4,567E-03 0,02306025 ! thymic T cell selection GO:0045061 15 7 0,000 4,567E-03 0,02301129 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 4,567E-03 0,02296254 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 4,567E-03 0,02291399 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 4,567E-03 0,02286565 ! ovulation GO:0030728 8 7 0,000 4,567E-03 0,02281751 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 4,567E-03 0,02276957 ! histidine metabolic process GO:0006547 7 7 0,000 4,567E-03 0,02272184 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 4,567E-03 0,0226743 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 4,567E-03 0,02262697 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 4,567E-03 0,02257983 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 4,567E-03 0,02253288 ! thyroid hormone generation GO:0006590 11 7 0,000 4,567E-03 0,02248614 ! endosome organization GO:0007032 10 7 0,000 4,567E-03 0,02243958 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 4,567E-03 0,02239322 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 4,567E-03 0,02234705 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 4,567E-03 0,02230106 ! urea metabolic process GO:0019627 9 7 0,000 4,567E-03 0,02225527 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 4,567E-03 0,02220967 ! vesicle fusion GO:0006906 15 7 0,000 4,567E-03 0,02216425 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 4,567E-03 0,02211901 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 4,567E-03 0,02207397 ! intracellular pH reduction GO:0051452 11 7 0,000 4,567E-03 0,0220291 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 4,567E-03 0,02198442 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 4,567E-03 0,02193991 ! organ growth GO:0035265 13 7 0,000 4,567E-03 0,02189559 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 4,567E-03 0,02185145 ! Rac protein signal transduction GO:0016601 7 7 0,000 4,567E-03 0,02180748 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 4,567E-03 0,02176369 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 4,567E-03 0,02172007 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 4,567E-03 0,02167663 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 4,567E-03 0,02163337 ! rRNA modification GO:0000154 12 7 0,000 4,567E-03 0,02159027 ! negative regulation of translational initiation GO:0045947 9 7 0,000 4,567E-03 0,02154735 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 4,567E-03 0,0215046 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 4,567E-03 0,02146201 ! protein heterooligomerization GO:0051291 10 7 0,000 4,567E-03 0,0214196 ! response to UV-B GO:0010224 11 7 0,000 4,567E-03 0,02137735 ! astrocyte development GO:0014002 15 7 0,000 4,567E-03 0,02133527 ! intermediate filament organization GO:0045109 12 7 0,000 4,567E-03 0,02129335 ! cardiac muscle cell development GO:0055013 9 7 0,000 4,567E-03 0,0212516 ! fibrinolysis GO:0042730 9 7 0,000 4,567E-03 0,02121001 ! peptidyl-arginine modification GO:0018195 9 7 0,000 4,567E-03 0,02116859 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 4,567E-03 0,02112732 ! blastoderm segmentation GO:0007350 11 7 0,000 4,567E-03 0,02108622 ! skeletal muscle contraction GO:0003009 8 7 0,000 4,567E-03 0,02104528 ! B cell lineage commitment GO:0002326 17 7 0,000 4,567E-03 0,02100449 ! DNA topological change GO:0006265 10 7 0,000 4,567E-03 0,02096386 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 4,567E-03 0,02092339 ! melanosome localization GO:0032400 10 7 0,000 4,567E-03 0,02088308 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 4,567E-03 0,02084292 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 4,567E-03 0,02080291 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 4,567E-03 0,02076306 ! mast cell activation GO:0045576 10 7 0,000 4,567E-03 0,02072336 ! multicellular organismal aging GO:0010259 11 7 0,000 4,567E-03 0,02068381 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 4,567E-03 0,02064441 ! gas homeostasis GO:0033483 12 7 0,000 4,567E-03 0,02060517 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 4,567E-03 0,02056607 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 4,567E-03 0,02052712 ! Schwann cell development GO:0014044 16 7 0,000 4,567E-03 0,02048831 ! dendrite morphogenesis GO:0048813 12 7 0,000 4,567E-03 0,02044966 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 4,567E-03 0,02041114 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 4,567E-03 0,02037278 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 4,567E-03 0,02033455 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 4,567E-03 0,02029647 ! neural tube patterning GO:0021532 8 7 0,000 4,567E-03 0,02025854 ! histone ubiquitination GO:0016574 10 7 0,000 4,567E-03 0,02022074 ! regulation of meiosis GO:0040020 12 7 0,000 4,567E-03 0,02018309 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 4,567E-03 0,02014557 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 4,567E-03 0,0201082 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 4,567E-03 0,02007096 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 4,567E-03 0,02003386 ! regulation of lipid transport GO:0032368 13 7 0,000 4,567E-03 0,0199969 ! regulation of cell division GO:0051302 9 7 0,000 4,567E-03 0,01996007 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 4,567E-03 0,01992338 ! neutrophil homeostasis GO:0001780 8 7 0,000 4,567E-03 0,01988682 ! regulation of macrophage activation GO:0043030 12 7 0,000 4,567E-03 0,0198504 ! negative regulation of nuclear division GO:0051784 18 7 0,000 4,567E-03 0,01981411 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 4,567E-03 0,01977795 ! diuresis GO:0030146 11 7 0,000 4,567E-03 0,01974193 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 4,567E-03 0,01970603 ! positive regulation of epidermis development GO:0045684 11 7 0,000 4,567E-03 0,01967027 ! thiamin metabolic process GO:0006772 8 7 0,000 4,567E-03 0,01963463 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 4,567E-03 0,01959913 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 4,567E-03 0,01956375 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 4,567E-03 0,0195285 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 4,567E-03 0,01949338 ! dopamine biosynthetic process GO:0042416 15 7 0,000 4,567E-03 0,01945838 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 4,567E-03 0,01942351 ! lymph node development GO:0048535 9 7 0,000 4,567E-03 0,01938876 ! anterior/posterior axis specification GO:0009948 11 7 0,000 4,567E-03 0,01935414 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 4,567E-03 0,01931964 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 4,567E-03 0,01928526 ! positive regulation of glucose import GO:0046326 7 7 0,000 4,567E-03 0,01925101 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 4,567E-03 0,01921687 ! ATP catabolic process GO:0006200 10 7 0,000 4,567E-03 0,01918286 ! establishment of pigment granule localization GO:0051905 13 7 0,000 4,567E-03 0,01914897 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 4,567E-03 0,0191152 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 4,567E-03 0,01908154 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 4,567E-03 0,01904801 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 4,567E-03 0,01901459 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 4,567E-03 0,01898129 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,567E-03 0,01894811 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 4,567E-03 0,01891504 ! muscle adaptation GO:0043500 12 7 0,000 4,567E-03 0,01888209 ! amino sugar catabolic process GO:0046348 9 7 0,000 4,567E-03 0,01884925 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 4,567E-03 0,01881652 ! retina homeostasis GO:0001895 9 7 0,000 4,567E-03 0,01878391 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 4,567E-03 0,01875141 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 4,567E-03 0,01871903 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 4,567E-03 0,01868675 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 4,567E-03 0,01865459 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,567E-03 0,01862254 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 5,218E-03 0,02123999 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 5,218E-03 0,02120362 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 5,218E-03 0,02116737 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 5,218E-03 0,02113125 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 5,218E-03 0,02109525 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 5,218E-03 0,02105938 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 5,218E-03 0,02102362 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 5,218E-03 0,02098799 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 5,218E-03 0,02095247 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 5,218E-03 0,02091708 ! cell proliferation in forebrain GO:0021846 10 8 0,000 5,218E-03 0,02088181 ! neutral lipid catabolic process GO:0046461 11 8 0,000 5,218E-03 0,02084665 ! N-glycan processing GO:0006491 12 8 0,000 5,218E-03 0,02081162 ! Golgi to endosome transport GO:0006895 16 8 0,000 5,218E-03 0,0207767 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 5,218E-03 0,0207419 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 5,218E-03 0,02070721 ! mRNA stabilization GO:0048255 16 8 0,000 5,218E-03 0,02067264 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 5,218E-03 0,02063819 ! neurotransmitter uptake GO:0001504 10 8 0,000 5,218E-03 0,02060385 ! lipoprotein transport GO:0042953 14 8 0,000 5,218E-03 0,02056962 ! membrane hyperpolarization GO:0060081 11 8 0,000 5,218E-03 0,02053551 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 5,218E-03 0,02050151 ! keratinocyte proliferation GO:0043616 15 8 0,000 5,218E-03 0,02046762 ! middle ear morphogenesis GO:0042474 9 8 0,000 5,218E-03 0,02043385 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 5,218E-03 0,02040019 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 5,218E-03 0,02036663 ! bile acid and bile salt transport GO:0015721 12 8 0,000 5,218E-03 0,02033319 ! ganglioside metabolic process GO:0001573 16 8 0,000 5,218E-03 0,02029986 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 5,218E-03 0,02026663 ! reflex GO:0060004 16 8 0,000 5,218E-03 0,02023352 ! positive regulation of isotype switching GO:0045830 16 8 0,000 5,218E-03 0,02020051 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 5,218E-03 0,02016761 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 5,218E-03 0,02013482 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 5,218E-03 0,02010213 ! glycerolipid catabolic process GO:0046503 11 8 0,000 5,218E-03 0,02006955 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 5,218E-03 0,02003708 ! hemoglobin metabolic process GO:0020027 12 8 0,000 5,218E-03 0,02000471 ! ceramide biosynthetic process GO:0046513 9 8 0,000 5,218E-03 0,01997244 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 5,218E-03 0,01994028 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 5,218E-03 0,01990822 ! adrenal gland development GO:0030325 18 8 0,000 5,218E-03 0,01987626 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 5,218E-03 0,01984441 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 5,218E-03 0,01981266 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 5,218E-03 0,01978101 ! proline metabolic process GO:0006560 9 8 0,000 5,218E-03 0,01974946 ! polyamine biosynthetic process GO:0006596 9 8 0,000 5,218E-03 0,01971801 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 5,218E-03 0,01968667 ! regulation of pigmentation during development GO:0048070 18 8 0,000 5,218E-03 0,01965542 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 5,218E-03 0,01962427 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 5,218E-03 0,01959322 ! regulation of type I interferon production GO:0032479 8 8 0,000 5,218E-03 0,01956226 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 5,218E-03 0,01953141 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 5,218E-03 0,01950065 ! galactose metabolic process GO:0006012 14 8 0,000 5,218E-03 0,01946999 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 5,218E-03 0,01943942 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,218E-03 0,01940895 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 5,218E-03 0,01937858 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 5,218E-03 0,0193483 ! ruffle organization GO:0031529 12 8 0,000 5,218E-03 0,01931812 ! osteoblast development GO:0002076 14 8 0,000 5,218E-03 0,01928803 ! macroautophagy GO:0016236 14 8 0,000 5,218E-03 0,01925803 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 5,218E-03 0,01922813 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 5,218E-03 0,01919831 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 5,218E-03 0,0191686 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 5,218E-03 0,01913897 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 5,218E-03 0,01910943 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 5,218E-03 0,01907999 ! protein retention in ER lumen GO:0006621 16 8 0,000 5,218E-03 0,01905063 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 5,218E-03 0,01902137 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 5,218E-03 0,0189922 ! regulation of circadian rhythm GO:0042752 13 8 0,000 5,218E-03 0,01896311 ! pigment granule localization GO:0051875 14 8 0,000 5,218E-03 0,01893412 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 5,218E-03 0,01890521 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 5,218E-03 0,01887639 ! response to tropane GO:0014073 14 8 0,000 5,218E-03 0,01884766 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 5,218E-03 0,01881902 ! embryonic axis specification GO:0000578 12 8 0,000 5,218E-03 0,01879046 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 5,218E-03 0,01876199 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 5,218E-03 0,0187336 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 5,218E-03 0,01870531 ! snRNA metabolic process GO:0016073 10 8 0,000 5,218E-03 0,01867709 GO:0016180|snRNA processing, ! regulation of focal adhesion formation GO:0051893 17 8 0,000 5,218E-03 0,01864896 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 5,218E-03 0,01862092 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 5,218E-03 0,01859296 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 5,218E-03 0,01856509 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 5,218E-03 0,01853729 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 5,218E-03 0,01850959 ! establishment of nucleus localization GO:0040023 14 8 0,000 5,218E-03 0,01848196 ! icosanoid secretion GO:0032309 12 8 0,000 5,218E-03 0,01845442 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 5,218E-03 0,01842695 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 5,218E-03 0,01839957 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 5,218E-03 0,01837227 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 5,218E-03 0,01834506 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 5,218E-03 0,01831792 ! S phase GO:0051320 8 8 0,000 5,218E-03 0,01829086 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 5,218E-03 0,01826388 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 5,218E-03 0,01823698 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 5,218E-03 0,01821017 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 5,218E-03 0,01818343 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 5,218E-03 0,01815676 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 5,218E-03 0,01813018 ! melanin biosynthetic process GO:0042438 11 8 0,000 5,218E-03 0,01810367 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 5,218E-03 0,01807724 ! regulation of synaptogenesis GO:0051963 12 8 0,000 5,218E-03 0,01805089 ! hormone catabolic process GO:0042447 13 8 0,000 5,218E-03 0,01802462 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 5,218E-03 0,01799842 ! quaternary ammonium group transport GO:0015697 10 8 0,000 5,218E-03 0,0179723 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 5,218E-03 0,01794625 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 5,218E-03 0,01792028 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 5,218E-03 0,01789438 ! regulation of telomere maintenance GO:0032204 10 8 0,000 5,218E-03 0,01786856 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 5,218E-03 0,01784281 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 5,218E-03 0,01781714 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 5,218E-03 0,01779154 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 5,218E-03 0,01776602 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 5,218E-03 0,01774056 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 5,218E-03 0,01771518 ! negative regulation of B cell activation GO:0050869 17 8 0,000 5,218E-03 0,01768988 ! behavioral response to nicotine GO:0035095 13 8 0,000 5,218E-03 0,01766464 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,218E-03 0,01763948 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 5,218E-03 0,01761439 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 5,218E-03 0,01758936 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 5,218E-03 0,01756442 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 5,218E-03 0,01753954 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 5,869E-03 0,01969813 ! regulation of developmental growth GO:0048638 14 9 0,000 5,869E-03 0,0196703 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 5,869E-03 0,01964256 ! telencephalon cell migration GO:0022029 16 9 0,000 5,869E-03 0,0196149 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 5,869E-03 0,01958731 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 5,869E-03 0,0195598 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 5,869E-03 0,01953236 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 5,869E-03 0,01950501 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 5,869E-03 0,01947773 ! cell volume homeostasis GO:0006884 14 9 0,000 5,869E-03 0,01945052 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 5,869E-03 0,0194234 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 5,869E-03 0,01939635 ! UTP metabolic process GO:0046051 10 9 0,000 5,869E-03 0,01936937 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 5,869E-03 0,01934247 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 5,869E-03 0,01931564 ! smoothened signaling pathway GO:0007224 10 9 0,000 5,869E-03 0,01928889 ! protein complex disassembly GO:0043241 17 9 0,000 5,869E-03 0,01926221 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 5,869E-03 0,0192356 ! estrogen metabolic process GO:0008210 16 9 0,000 5,869E-03 0,01920907 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 5,869E-03 0,01918261 ! photoreceptor cell development GO:0042461 17 9 0,000 5,869E-03 0,01915623 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 5,869E-03 0,01912991 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 5,869E-03 0,01910367 ! microtubule bundle formation GO:0001578 14 9 0,000 5,869E-03 0,0190775 ! T-helper 1 type immune response GO:0042088 13 9 0,000 5,869E-03 0,0190514 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 5,869E-03 0,01902538 ! lung alveolus development GO:0048286 18 9 0,000 5,869E-03 0,01899942 ! ciliary or flagellar motility GO:0001539 10 9 0,000 5,869E-03 0,01897354 ! pseudouridine synthesis GO:0001522 10 9 0,000 5,869E-03 0,01894772 ! endothelial cell differentiation GO:0045446 17 9 0,000 5,869E-03 0,01892198 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 5,869E-03 0,0188963 ! regulation of exit from mitosis GO:0007096 12 9 0,000 5,869E-03 0,0188707 ! endoderm development GO:0007492 12 9 0,000 5,869E-03 0,01884516 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 5,869E-03 0,0188197 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 5,869E-03 0,0187943 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 5,869E-03 0,01876897 ! astrocyte differentiation GO:0048708 17 9 0,000 5,869E-03 0,01874371 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 5,869E-03 0,01871852 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 5,869E-03 0,01869339 ! phosphagen metabolic process GO:0006599 12 9 0,000 5,869E-03 0,01866833 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 5,869E-03 0,01864334 ! reverse cholesterol transport GO:0043691 17 9 0,000 5,869E-03 0,01861842 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 5,869E-03 0,01859356 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 5,869E-03 0,01856877 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 5,869E-03 0,01854404 ! macrophage activation GO:0042116 14 9 0,000 5,869E-03 0,01851938 ! multicellular organism growth GO:0035264 16 9 0,000 5,869E-03 0,01849479 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 5,869E-03 0,01847026 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 5,869E-03 0,0184458 ! neuron apoptosis GO:0051402 12 9 0,000 5,869E-03 0,0184214 ! lens development in camera-type eye GO:0002088 11 9 0,000 5,869E-03 0,01839706 ! positive regulation of vasodilation GO:0045909 14 9 0,000 5,869E-03 0,01837279 ! retinoic acid metabolic process GO:0042573 11 9 0,000 5,869E-03 0,01834858 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 5,869E-03 0,01832444 ! positive regulation of translational initiation GO:0045948 10 9 0,000 5,869E-03 0,01830036 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 5,869E-03 0,01827635 ! Schwann cell differentiation GO:0014037 20 9 0,000 5,869E-03 0,01825239 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 5,869E-03 0,0182285 ! regulation of gliogenesis GO:0014013 21 9 0,000 5,869E-03 0,01820467 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 5,869E-03 0,01818091 ! oligodendrocyte development GO:0014003 13 9 0,000 5,869E-03 0,0181572 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 5,869E-03 0,01813356 ! segment specification GO:0007379 11 9 0,000 5,869E-03 0,01810998 ! cellular extravasation GO:0045123 12 9 0,000 5,869E-03 0,01808646 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 5,869E-03 0,018063 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 5,869E-03 0,01803961 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 5,869E-03 0,01801627 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 5,869E-03 0,01799299 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 5,869E-03 0,01796978 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 5,869E-03 0,01794662 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 5,869E-03 0,01792352 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 5,869E-03 0,01790048 ! response to amine stimulus GO:0014075 13 9 0,000 5,869E-03 0,0178775 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 5,869E-03 0,01785458 ! erythrocyte development GO:0048821 13 9 0,000 5,869E-03 0,01783172 ! renal water homeostasis GO:0003091 13 9 0,000 5,869E-03 0,01780892 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 5,869E-03 0,01778618 ! nucleosome disassembly GO:0006337 13 9 0,000 5,869E-03 0,01776349 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 5,869E-03 0,01774086 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 5,869E-03 0,01771829 ! induction of an organ GO:0001759 13 9 0,000 5,869E-03 0,01769578 ! leukocyte activation during immune response GO:0002366 15 9 0,000 5,869E-03 0,01767332 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 5,869E-03 0,01765092 ! cerebellum morphogenesis GO:0021587 13 9 0,000 5,869E-03 0,01762858 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 5,869E-03 0,01760629 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 5,869E-03 0,01758406 ! sterol catabolic process GO:0016127 11 9 0,000 5,869E-03 0,01756189 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 5,869E-03 0,01753977 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 5,869E-03 0,01751771 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 5,869E-03 0,0174957 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 5,869E-03 0,01747375 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 5,869E-03 0,01745185 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 5,869E-03 0,01743001 ! prophase GO:0051324 12 9 0,000 5,869E-03 0,01740822 ! neuroblast proliferation GO:0007405 19 9 0,000 5,869E-03 0,01738649 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 5,869E-03 0,01736481 ! peptidyl-threonine modification GO:0018210 22 9 0,000 5,869E-03 0,01734318 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 5,869E-03 0,01732161 ! ubiquinone metabolic process GO:0006743 11 9 0,000 5,869E-03 0,01730009 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 5,869E-03 0,01727863 ! acid secretion GO:0046717 14 9 0,000 5,869E-03 0,01725722 ! purine base metabolic process GO:0006144 18 9 0,000 5,869E-03 0,01723586 ! detection of calcium ion GO:0005513 13 9 0,000 5,869E-03 0,01721456 ! myeloid cell homeostasis GO:0002262 10 9 0,000 5,869E-03 0,0171933 ! regulation of fibrinolysis GO:0051917 14 9 0,000 5,869E-03 0,0171721 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 5,869E-03 0,01715096 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 5,869E-03 0,01712986 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 5,869E-03 0,01710882 ! regulation of muscle adaptation GO:0043502 12 9 0,000 5,869E-03 0,01708782 ! regulation of amino acid transport GO:0051955 11 9 0,000 5,869E-03 0,01706688 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 5,869E-03 0,01704599 ! prepulse inhibition GO:0060134 14 9 0,000 5,869E-03 0,01702515 ! sequestering of metal ion GO:0051238 12 9 0,000 5,869E-03 0,01700437 ! lamellipodium assembly GO:0030032 12 9 0,000 5,869E-03 0,01698363 ! regulation of embryonic development GO:0045995 17 9 0,000 5,869E-03 0,01696294 ! mitochondrion localization GO:0051646 15 9 0,000 5,869E-03 0,01694231 ! localization within membrane GO:0051668 15 9 0,000 5,869E-03 0,01692172 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 6,519E-03 0,01877343 ! axon extension GO:0048675 13 10 0,000 6,519E-03 0,01875068 ! neuron fate specification GO:0048665 12 10 0,000 6,519E-03 0,01872797 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 6,519E-03 0,01870533 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 6,519E-03 0,01868274 ! associative learning GO:0008306 19 10 0,000 6,519E-03 0,0186602 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 6,519E-03 0,01863772 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 6,519E-03 0,01861529 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 6,519E-03 0,01859292 ! CTP metabolic process GO:0046036 11 10 0,000 6,519E-03 0,0185706 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 6,519E-03 0,01854833 ! GTP metabolic process GO:0046039 11 10 0,000 6,519E-03 0,01852612 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 6,519E-03 0,01850396 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 6,519E-03 0,01848185 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 6,519E-03 0,01845979 ! social behavior GO:0035176 15 10 0,000 6,519E-03 0,01843779 ! sulfate transport GO:0008272 12 10 0,000 6,519E-03 0,01841584 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 6,519E-03 0,01839394 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 6,519E-03 0,0183721 ! artery development GO:0060840 20 10 0,000 6,519E-03 0,0183503 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 6,519E-03 0,01832856 ! response to pain GO:0048265 20 10 0,000 6,519E-03 0,01830687 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 6,519E-03 0,01828523 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 6,519E-03 0,01826364 ! phospholipid efflux GO:0033700 17 10 0,000 6,519E-03 0,01824211 ! hippocampus development GO:0021766 19 10 0,000 6,519E-03 0,01822062 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 6,519E-03 0,01819918 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 6,519E-03 0,0181778 ! blood vessel remodeling GO:0001974 23 10 0,000 6,519E-03 0,01815646 ! positive regulation of heart contraction GO:0045823 16 10 0,000 6,519E-03 0,01813518 ! pathogenesis GO:0009405 13 10 0,000 6,519E-03 0,01811394 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 6,519E-03 0,01809276 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 6,519E-03 0,01807162 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 6,519E-03 0,01805053 ! protein targeting to ER GO:0045047 21 10 0,000 6,519E-03 0,0180295 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 6,519E-03 0,01800851 ! arginine catabolic process GO:0006527 12 10 0,000 6,519E-03 0,01798757 ! melanocyte differentiation GO:0030318 16 10 0,000 6,519E-03 0,01796667 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 6,519E-03 0,01794583 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 6,519E-03 0,01792504 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 6,519E-03 0,01790429 ! regulation of stress fiber formation GO:0051492 24 10 0,000 6,519E-03 0,01788359 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 6,519E-03 0,01786294 ! B cell proliferation GO:0042100 16 10 0,000 6,519E-03 0,01784234 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 6,519E-03 0,01782178 ! mannose metabolic process GO:0006013 11 10 0,000 6,519E-03 0,01780127 ! regulation of sodium ion transport GO:0002028 15 10 0,000 6,519E-03 0,01778081 ! forebrain cell migration GO:0021885 17 10 0,000 6,519E-03 0,0177604 ! lipid digestion GO:0044241 15 10 0,000 6,519E-03 0,01774003 ! substrate-bound cell migration GO:0006929 11 10 0,000 6,519E-03 0,01771971 ! phagocytosis, engulfment GO:0006911 20 10 0,000 6,519E-03 0,01769944 ! receptor clustering GO:0043113 18 10 0,000 6,519E-03 0,01767921 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 6,519E-03 0,01765903 ! UV protection GO:0009650 14 10 0,000 6,519E-03 0,01763889 ! entry into host cell GO:0030260 21 10 0,000 6,519E-03 0,0176188 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 6,519E-03 0,01759876 ! behavioral fear response GO:0001662 19 10 0,000 6,519E-03 0,01757876 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 6,519E-03 0,0175588 ! negative regulation of ossification GO:0030279 21 10 0,000 6,519E-03 0,0175389 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 6,519E-03 0,01751903 ! protein homotetramerization GO:0051289 20 10 0,000 6,519E-03 0,01749922 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 6,519E-03 0,01747944 ! response to dsRNA GO:0043331 19 10 0,000 6,519E-03 0,01745971 ! DNA ligation GO:0006266 16 10 0,000 6,519E-03 0,01744003 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 6,519E-03 0,01742039 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 6,519E-03 0,0174008 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 6,519E-03 0,01738124 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 6,519E-03 0,01736174 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 6,519E-03 0,01734227 ! postreplication repair GO:0006301 16 10 0,000 6,519E-03 0,01732285 ! fucose catabolic process GO:0019317 17 10 0,000 6,519E-03 0,01730348 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 6,519E-03 0,01728414 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 6,519E-03 0,01726485 ! hindbrain morphogenesis GO:0021575 16 10 0,000 6,519E-03 0,0172456 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 6,519E-03 0,0172264 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 6,519E-03 0,01720724 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 6,519E-03 0,01718812 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 6,519E-03 0,01716904 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 6,519E-03 0,01715001 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 6,519E-03 0,01713102 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 6,519E-03 0,01711207 ! methionine biosynthetic process GO:0009086 13 10 0,000 6,519E-03 0,01709316 ! oocyte differentiation GO:0009994 14 10 0,000 6,519E-03 0,01707429 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 6,519E-03 0,01705547 ! spleen development GO:0048536 17 10 0,000 6,519E-03 0,01703668 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 6,519E-03 0,01701794 ! regulation of RNA splicing GO:0043484 15 10 0,000 6,519E-03 0,01699924 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 6,519E-03 0,01698058 ! blastocyst formation GO:0001825 14 10 0,000 6,519E-03 0,01696196 ! embryonic gut development GO:0048566 13 10 0,000 6,519E-03 0,01694338 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 6,519E-03 0,01692484 ! cerebellar cortex development GO:0021695 14 10 0,000 6,519E-03 0,01690635 ! activation of innate immune response GO:0002218 10 10 0,000 6,519E-03 0,01688789 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 6,519E-03 0,01686947 ! insulin secretion GO:0030073 18 10 0,000 6,519E-03 0,0168511 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 6,519E-03 0,01683276 ! response to nicotine GO:0035094 18 10 0,000 6,519E-03 0,01681446 ! establishment of cell polarity GO:0030010 12 10 0,000 6,519E-03 0,01679621 ! nucleus localization GO:0051647 16 10 0,000 6,519E-03 0,01677799 ! regulation of synapse organization GO:0050807 14 10 0,000 6,519E-03 0,01675981 ! negative regulation of muscle development GO:0048635 14 11 0,000 7,169E-03 0,01841029 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 7,169E-03 0,01839039 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 7,169E-03 0,01837053 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 7,169E-03 0,01835071 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 7,169E-03 0,01833093 ! virus-host interaction GO:0019048 20 11 0,000 7,169E-03 0,0183112 ! thyroid gland development GO:0030878 20 11 0,000 7,169E-03 0,01829151 ! pentose-phosphate shunt GO:0006098 14 11 0,000 7,169E-03 0,01827187 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 7,169E-03 0,01825226 ! non-recombinational repair GO:0000726 19 11 0,000 7,169E-03 0,0182327 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 7,169E-03 0,01821318 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 7,169E-03 0,0181937 ! Golgi vesicle budding GO:0048194 18 11 0,000 7,169E-03 0,01817426 ! elastic fiber assembly GO:0048251 17 11 0,000 7,169E-03 0,01815486 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 7,169E-03 0,01813551 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 7,169E-03 0,01811619 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 7,169E-03 0,01809692 ! regulation of cell projection assembly GO:0060491 22 11 0,000 7,169E-03 0,01807769 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 7,169E-03 0,0180585 ! bone resorption GO:0045453 16 11 0,000 7,169E-03 0,01803935 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 7,169E-03 0,01802024 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 7,169E-03 0,01800117 ! ventral spinal cord development GO:0021517 15 11 0,000 7,169E-03 0,01798214 ! regulated secretory pathway GO:0045055 15 11 0,000 7,169E-03 0,01796315 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 7,169E-03 0,01794421 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 7,169E-03 0,0179253 ! syncytium formation GO:0006949 15 11 0,000 7,169E-03 0,01790643 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 7,169E-03 0,0178876 ! glucan biosynthetic process GO:0009250 14 11 0,000 7,169E-03 0,01786881 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 7,169E-03 0,01785006 ! Golgi organization GO:0007030 19 11 0,000 7,169E-03 0,01783135 ! response to X-ray GO:0010165 19 11 0,000 7,169E-03 0,01781268 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 7,169E-03 0,01779404 ! adult heart development GO:0007512 12 11 0,000 7,169E-03 0,01777545 ! chondrocyte differentiation GO:0002062 17 11 0,000 7,169E-03 0,0177569 ! epithelial cell development GO:0002064 16 11 0,000 7,169E-03 0,01773838 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 7,169E-03 0,0177199 ! temperature homeostasis GO:0001659 16 11 0,000 7,169E-03 0,01770146 ! L-glutamate transport GO:0015813 15 11 0,000 7,169E-03 0,01768306 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 7,169E-03 0,0176647 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 7,169E-03 0,01764638 ! motor axon guidance GO:0008045 17 11 0,000 7,169E-03 0,01762809 ! copper ion homeostasis GO:0055070 15 11 0,000 7,169E-03 0,01760984 ! protein targeting to peroxisome GO:0006625 21 11 0,000 7,169E-03 0,01759163 ! regulation of bone resorption GO:0045124 27 11 0,000 7,169E-03 0,01757346 ! stem cell development GO:0048864 30 11 0,000 7,169E-03 0,01755532 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 7,169E-03 0,01753722 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 7,169E-03 0,01751916 ! regulation of phagocytosis GO:0050764 16 11 0,000 7,169E-03 0,01750114 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 7,169E-03 0,01748315 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 7,169E-03 0,0174652 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 7,169E-03 0,01744729 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 7,169E-03 0,01742941 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 7,169E-03 0,01741157 ! regulation of B cell differentiation GO:0045577 23 11 0,000 7,169E-03 0,01739377 ! cranial nerve development GO:0021545 14 11 0,000 7,169E-03 0,017376 ! nitric oxide metabolic process GO:0046209 15 11 0,000 7,169E-03 0,01735827 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 7,169E-03 0,01734058 ! salivary gland development GO:0007431 24 11 0,000 7,169E-03 0,01732292 ! negative regulation of neurological system process GO:0031645 20 11 0,000 7,169E-03 0,0173053 ! regulation of leukocyte migration GO:0002685 25 11 0,000 7,169E-03 0,01728771 ! musculoskeletal movement GO:0050881 16 11 0,000 7,169E-03 0,01727016 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 7,169E-03 0,01725264 ! protein-chromophore linkage GO:0018298 13 11 0,000 7,169E-03 0,01723516 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 7,169E-03 0,01721772 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 7,169E-03 0,01720031 ! cholesterol efflux GO:0033344 20 11 0,000 7,169E-03 0,01718294 ! digestive tract morphogenesis GO:0048546 16 11 0,000 7,169E-03 0,0171656 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 7,169E-03 0,01714829 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 7,169E-03 0,01713102 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 7,169E-03 0,01711379 ! negative regulation of glucose import GO:0046325 14 11 0,000 7,169E-03 0,01709659 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 7,169E-03 0,01707942 ! regulation of organic acid transport GO:0032890 17 11 0,000 7,169E-03 0,01706229 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 7,169E-03 0,0170452 ! cardiac cell differentiation GO:0035051 18 11 0,000 7,169E-03 0,01702814 ! defense response to fungus GO:0050832 13 11 0,000 7,169E-03 0,01701111 ! lysogeny GO:0030069 20 11 0,000 7,169E-03 0,01699411 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 7,169E-03 0,01697715 ! acrosome reaction GO:0007340 14 11 0,000 7,169E-03 0,01696023 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 7,169E-03 0,01694333 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 7,169E-03 0,01692647 ! rRNA transcription GO:0009303 19 12 0,000 7,818E-03 0,01844133 ! reproductive cellular process GO:0048610 15 12 0,000 7,818E-03 0,01842302 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 7,818E-03 0,01840474 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 7,818E-03 0,0183865 ! dicarboxylic acid transport GO:0006835 21 12 0,000 7,818E-03 0,01836829 ! phosphate transport GO:0006817 15 12 0,000 7,818E-03 0,01835012 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 7,818E-03 0,01833199 ! peroxisomal transport GO:0043574 22 12 0,000 7,818E-03 0,0183139 ! mating GO:0007618 16 12 0,000 7,818E-03 0,01829583 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 7,818E-03 0,01827781 ! heart looping GO:0001947 15 12 0,000 7,818E-03 0,01825982 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 7,818E-03 0,01824186 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 7,818E-03 0,01822395 ! negative regulation of proteolysis GO:0045861 17 12 0,000 7,818E-03 0,01820606 ! T cell selection GO:0045058 25 12 0,000 7,818E-03 0,01818821 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 7,818E-03 0,0181704 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 7,818E-03 0,01815262 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 7,818E-03 0,01813487 ! plasma membrane organization GO:0007009 19 12 0,000 7,818E-03 0,01811716 ! focal adhesion formation GO:0048041 28 12 0,000 7,818E-03 0,01809949 ! mitotic spindle organization GO:0007052 16 12 0,000 7,818E-03 0,01808185 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 7,818E-03 0,01806424 ! regulation of intracellular pH GO:0051453 19 12 0,000 7,818E-03 0,01804667 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 7,818E-03 0,01802913 ! monoamine transport GO:0015844 14 12 0,000 7,818E-03 0,01801163 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 7,818E-03 0,01799416 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 7,818E-03 0,01797672 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 7,818E-03 0,01795932 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 7,818E-03 0,01794195 ! regulation of organ growth GO:0046620 14 12 0,000 7,818E-03 0,01792461 ! vasoconstriction GO:0042310 18 12 0,000 7,818E-03 0,01790731 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 7,818E-03 0,01789004 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 7,818E-03 0,01787281 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 7,818E-03 0,01785561 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 7,818E-03 0,01783844 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 7,818E-03 0,0178213 ! histone deacetylation GO:0016575 14 12 0,000 7,818E-03 0,0178042 ! histone acetylation GO:0016573 27 12 0,000 7,818E-03 0,01778713 ! DNA methylation GO:0006306 19 12 0,000 7,818E-03 0,01777009 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 7,818E-03 0,01775309 ! protein sumoylation GO:0016925 14 12 0,000 7,818E-03 0,01773611 ! chromatin silencing GO:0006342 23 12 0,000 7,818E-03 0,01771917 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 7,818E-03 0,01770227 ! gland morphogenesis GO:0022612 24 12 0,000 7,818E-03 0,01768539 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 7,818E-03 0,01766855 ! zymogen activation GO:0031638 16 12 0,000 7,818E-03 0,01765174 ! peptidyl-lysine modification GO:0018205 21 12 0,000 7,818E-03 0,01763496 ! nucleosome positioning GO:0016584 13 12 0,000 7,818E-03 0,01761821 ! T cell homeostasis GO:0043029 22 12 0,000 7,818E-03 0,0176015 ! regulation of isotype switching GO:0045191 22 12 0,000 7,818E-03 0,01758481 ! glutathione biosynthetic process GO:0006750 14 12 0,000 7,818E-03 0,01756816 ! response to gamma radiation GO:0010332 21 12 0,000 7,818E-03 0,01755154 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 7,818E-03 0,01753495 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 7,818E-03 0,01751839 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 7,818E-03 0,01750186 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 7,818E-03 0,01748537 ! cAMP biosynthetic process GO:0006171 20 12 0,000 7,818E-03 0,0174689 ! male genitalia development GO:0030539 15 12 0,000 7,818E-03 0,01745247 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 7,818E-03 0,01743607 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 7,818E-03 0,0174197 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 7,818E-03 0,01740335 ! developmental induction GO:0031128 16 12 0,000 7,818E-03 0,01738704 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 7,818E-03 0,01737076 ! response to cold GO:0009409 15 12 0,000 7,818E-03 0,01735451 ! negative regulation of immune effector process GO:0002698 20 12 0,000 7,818E-03 0,0173383 ! respiratory burst GO:0045730 22 13 0,000 8,467E-03 0,01875996 ! lactation GO:0007595 22 13 0,000 8,467E-03 0,01874246 ! tRNA modification GO:0006400 15 13 0,000 8,467E-03 0,01872499 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 8,467E-03 0,01870756 ! positive regulation of blood pressure GO:0045777 19 13 0,000 8,467E-03 0,01869015 ! cGMP metabolic process GO:0046068 16 13 0,000 8,467E-03 0,01867278 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 8,467E-03 0,01865545 ! water transport GO:0006833 21 13 0,000 8,467E-03 0,01863814 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 8,467E-03 0,01862087 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 8,467E-03 0,01860362 ! copper ion transport GO:0006825 15 13 0,000 8,467E-03 0,01858642 ! filopodium assembly GO:0046847 21 13 0,000 8,467E-03 0,01856924 ! lipid localization GO:0010876 25 13 0,000 8,467E-03 0,01855209 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 8,467E-03 0,01853498 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 8,467E-03 0,01851789 ! cytokine biosynthetic process GO:0042089 17 13 0,000 8,467E-03 0,01850084 ! T cell proliferation GO:0042098 24 13 0,000 8,467E-03 0,01848382 ! organelle fusion GO:0048284 29 13 0,000 8,467E-03 0,01846683 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 8,467E-03 0,01844988 ! endocrine pancreas development GO:0031018 19 13 0,000 8,467E-03 0,01843295 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 8,467E-03 0,01841605 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 8,467E-03 0,01839919 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 8,467E-03 0,01838236 ! regulation of mRNA processing GO:0050684 21 13 0,000 8,467E-03 0,01836555 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 8,467E-03 0,01834878 ! methionine metabolic process GO:0006555 16 13 0,000 8,467E-03 0,01833204 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 8,467E-03 0,01831533 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 8,467E-03 0,01829865 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 8,467E-03 0,018282 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 8,467E-03 0,01826538 ! membrane protein proteolysis GO:0033619 21 13 0,000 8,467E-03 0,01824879 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 8,467E-03 0,01823223 ! neutral amino acid transport GO:0015804 20 13 0,000 8,467E-03 0,0182157 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 8,467E-03 0,0181992 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 8,467E-03 0,01818273 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 8,467E-03 0,01816629 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 8,467E-03 0,01814988 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 8,467E-03 0,0181335 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 8,467E-03 0,01811715 ! cellular pigmentation GO:0033059 24 13 0,000 8,467E-03 0,01810082 ! histone methylation GO:0016571 16 13 0,000 8,467E-03 0,01808453 ! regulation of epidermis development GO:0045682 21 13 0,000 8,467E-03 0,01806827 ! oxygen transport GO:0015671 20 13 0,000 8,467E-03 0,01805203 ! regulation of axon extension GO:0030516 26 13 0,000 8,467E-03 0,01803583 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 8,467E-03 0,01801965 ! detection of bacterium GO:0016045 13 13 0,000 8,467E-03 0,01800351 ! L-fucose metabolic process GO:0042354 21 13 0,000 8,467E-03 0,01798739 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 8,467E-03 0,0179713 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 8,467E-03 0,01795524 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 8,467E-03 0,01793921 ! actin filament polymerization GO:0030041 18 13 0,000 8,467E-03 0,01792321 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 9,115E-03 0,0192789 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 9,115E-03 0,01926173 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 9,115E-03 0,01924459 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 9,115E-03 0,01922749 ! neuron maturation GO:0042551 24 14 0,000 9,115E-03 0,01921041 ! regulation of S phase GO:0033261 25 14 0,000 9,115E-03 0,01919337 ! regulation of chemokine production GO:0032642 18 14 0,000 9,115E-03 0,01917635 ! myotube differentiation GO:0014902 21 14 0,000 9,115E-03 0,01915937 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 9,115E-03 0,01914241 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 9,115E-03 0,01912549 ! phospholipid catabolic process GO:0009395 19 14 0,000 9,115E-03 0,01910859 ! aminoglycan catabolic process GO:0006026 19 14 0,000 9,115E-03 0,01909172 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 9,115E-03 0,01907489 ! cardiac muscle contraction GO:0060048 28 14 0,000 9,115E-03 0,01905808 ! RNA polyadenylation GO:0043631 21 14 0,000 9,115E-03 0,01904131 ! cartilage condensation GO:0001502 22 14 0,000 9,115E-03 0,01902456 ! gene silencing by RNA GO:0031047 22 14 0,000 9,115E-03 0,01900784 ! response to cAMP GO:0051591 20 14 0,000 9,115E-03 0,01899115 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 9,115E-03 0,01897449 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 9,115E-03 0,01895787 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 9,115E-03 0,01894126 ! limbic system development GO:0021761 25 14 0,000 9,115E-03 0,01892469 ! positive regulation of ion transport GO:0043270 18 14 0,000 9,115E-03 0,01890815 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 9,115E-03 0,01889164 ! palate development GO:0060021 19 14 0,000 9,115E-03 0,01887515 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 9,115E-03 0,0188587 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 9,115E-03 0,01884227 ! regulation of defense response to virus GO:0050688 26 14 0,000 9,115E-03 0,01882587 ! response to hexose stimulus GO:0009746 22 14 0,000 9,115E-03 0,0188095 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 9,115E-03 0,01879316 ! arginine metabolic process GO:0006525 17 14 0,000 9,115E-03 0,01877684 ! glutamate metabolic process GO:0006536 21 14 0,000 9,115E-03 0,01876056 ! glycine metabolic process GO:0006544 22 14 0,000 9,115E-03 0,0187443 ! pituitary gland development GO:0021983 24 14 0,000 9,115E-03 0,01872807 ! tyrosine metabolic process GO:0006570 20 14 0,000 9,115E-03 0,01871187 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 9,115E-03 0,0186957 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 9,115E-03 0,01867955 ! cytokine metabolic process GO:0042107 18 14 0,000 9,115E-03 0,01866344 ! NAD metabolic process GO:0019674 25 14 0,000 9,115E-03 0,01864735 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 9,115E-03 0,01863129 ! regulation of heart rate GO:0002027 26 14 0,000 9,115E-03 0,01861525 ! exocrine system development GO:0035272 29 14 0,000 9,115E-03 0,01859925 ! negative regulation of caspase activity GO:0043154 22 14 0,000 9,115E-03 0,01858327 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 9,115E-03 0,01856732 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 9,115E-03 0,01855139 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 9,115E-03 0,0185355 ! axon cargo transport GO:0008088 29 14 0,000 9,115E-03 0,01851963 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 9,115E-03 0,01850378 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 9,115E-03 0,01848797 ! genitalia development GO:0048806 18 14 0,000 9,115E-03 0,01847218 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 9,115E-03 0,01845642 ! autonomic nervous system development GO:0048483 26 14 0,000 9,115E-03 0,01844069 ! tissue regeneration GO:0042246 24 14 0,000 9,115E-03 0,01842498 ! negative regulation of protein secretion GO:0050709 22 14 0,000 9,115E-03 0,0184093 ! water homeostasis GO:0030104 23 14 0,000 9,115E-03 0,01839364 ! cofactor transport GO:0051181 22 14 0,000 9,115E-03 0,01837802 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 9,115E-03 0,01836241 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 9,115E-03 0,01834684 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 9,115E-03 0,01833129 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 9,115E-03 0,01831577 ! regulation of mRNA stability GO:0043488 30 14 0,000 9,115E-03 0,01830027 ! cell killing GO:0001906 22 14 0,000 9,115E-03 0,0182848 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 9,115E-03 0,01826936 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 9,115E-03 0,01825394 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 9,115E-03 0,01823855 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 9,115E-03 0,01822319 ! microspike assembly GO:0030035 25 14 0,000 9,115E-03 0,01820785 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 9,115E-03 0,01819253 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 9,764E-03 0,01946975 ! superoxide anion generation GO:0042554 19 15 0,000 9,764E-03 0,0194534 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 9,764E-03 0,01943708 ! skin development GO:0043588 28 15 0,000 9,764E-03 0,01942079 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 9,764E-03 0,01940453 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 9,764E-03 0,01938829 ! inositol metabolic process GO:0006020 21 15 0,000 9,764E-03 0,01937208 ! retina development in camera-type eye GO:0060041 22 15 0,000 9,764E-03 0,01935589 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 9,764E-03 0,01933974 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 9,764E-03 0,01932361 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 9,764E-03 0,0193075 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 9,764E-03 0,01929143 ! activation of MAPKK activity GO:0000186 22 15 0,000 9,764E-03 0,01927538 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 9,764E-03 0,01925935 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 9,764E-03 0,01924336 ! glycoprotein catabolic process GO:0006516 26 15 0,000 9,764E-03 0,01922739 ! response to osmotic stress GO:0006970 23 15 0,000 9,764E-03 0,01921145 ! vesicle coating GO:0006901 26 15 0,000 9,764E-03 0,01919553 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 9,764E-03 0,01917964 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 9,764E-03 0,01916377 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 9,764E-03 0,01914794 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 9,764E-03 0,01913213 ! bone mineralization GO:0030282 17 15 0,000 9,764E-03 0,01911634 ! G1/S transition checkpoint GO:0031575 36 15 0,000 9,764E-03 0,01910058 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 9,764E-03 0,01908485 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 9,764E-03 0,01906914 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 9,764E-03 0,01905346 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 9,764E-03 0,0190378 ! regulation of cellular pH GO:0030641 23 15 0,000 9,764E-03 0,01902217 ! ribosome assembly GO:0042255 17 15 0,000 9,764E-03 0,01900657 ! cerebellum development GO:0021549 19 15 0,000 9,764E-03 0,01899099 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 9,764E-03 0,01897543 ! mRNA splice site selection GO:0006376 33 15 0,000 9,764E-03 0,0189599 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 9,764E-03 0,0189444 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 9,764E-03 0,01892892 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 9,764E-03 0,01891347 ! sphingolipid catabolic process GO:0030149 27 15 0,000 9,764E-03 0,01889805 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 9,764E-03 0,01888264 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 9,764E-03 0,01886727 ! muscle maintenance GO:0046716 21 15 0,000 9,764E-03 0,01885192 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 9,764E-03 0,01883659 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 9,764E-03 0,01882129 ! intestinal absorption GO:0050892 22 15 0,000 9,764E-03 0,01880601 ! regulation of ATPase activity GO:0043462 24 15 0,000 9,764E-03 0,01879076 ! dopamine metabolic process GO:0042417 32 15 0,000 9,764E-03 0,01877553 ! gas transport GO:0015669 23 15 0,000 9,764E-03 0,01876033 ! regulation of RNA stability GO:0043487 31 15 0,000 9,764E-03 0,01874515 ! organic cation transport GO:0015695 19 15 0,000 9,764E-03 0,01872999 ! heme biosynthetic process GO:0006783 22 15 0,000 9,764E-03 0,01871487 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 9,764E-03 0,01869976 ! lymphocyte homeostasis GO:0002260 29 15 0,000 9,764E-03 0,01868468 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 9,764E-03 0,01866962 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 9,764E-03 0,01865459 ! cilium assembly GO:0042384 22 15 0,000 9,764E-03 0,01863958 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 9,764E-03 0,0186246 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 9,764E-03 0,01860964 ! peptide hormone processing GO:0016486 23 15 0,000 9,764E-03 0,01859471 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 9,764E-03 0,01857979 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,01041136 0,0197966 ! bone remodeling GO:0046849 24 16 0,000 0,01041136 0,01978075 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,01041136 0,01976492 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,01041136 0,01974912 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,01041136 0,01973335 ! bile acid metabolic process GO:0008206 23 16 0,000 0,01041136 0,0197176 ! axis specification GO:0009798 26 16 0,000 0,01041136 0,01970188 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,01041136 0,01968618 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,01041136 0,01967051 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,01041136 0,01965486 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01041136 0,01963923 ! centrosome cycle GO:0007098 18 16 0,000 0,01041136 0,01962363 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,01041136 0,01960806 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,01041136 0,01959251 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,01041136 0,01957698 ! cellular response to starvation GO:0009267 26 16 0,000 0,01041136 0,01956148 ! DNA integration GO:0015074 25 16 0,000 0,01041136 0,01954601 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,01041136 0,01953056 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,01041136 0,01951513 ! regulation of exocytosis GO:0017157 28 16 0,000 0,01041136 0,01949973 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,01041136 0,01948435 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,01041136 0,019469 ! regulation of vasodilation GO:0042312 26 16 0,000 0,01041136 0,01945367 ! DNA replication initiation GO:0006270 26 16 0,000 0,01041136 0,01943836 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,01041136 0,01942308 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,01041136 0,01940782 ! neuron recognition GO:0008038 27 16 0,000 0,01041136 0,01939259 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,01041136 0,01937738 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,01041136 0,01936219 ! G1 phase GO:0051318 28 16 0,000 0,01041136 0,01934703 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,01041136 0,01933189 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01041136 0,01931677 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,01041136 0,01930168 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,01041136 0,01928662 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,01041136 0,01927157 ! NADP metabolic process GO:0006739 22 16 0,000 0,01041136 0,01925655 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,01041136 0,01924155 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,01041136 0,01922658 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,01041136 0,01921163 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,01041136 0,0191967 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01041136 0,0191818 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,01041136 0,01916692 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,01041136 0,01915206 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,01041136 0,01913722 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,01041136 0,01912241 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,01041136 0,01910762 ! defense response to virus GO:0051607 28 16 0,000 0,01041136 0,01909286 ! peptide hormone secretion GO:0030072 26 16 0,000 0,01041136 0,01907811 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,01105873 0,02024875 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,01105873 0,02023314 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,01105873 0,02021755 ! zinc ion transport GO:0006829 22 17 0,000 0,01105873 0,02020198 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01105873 0,02018644 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,01105873 0,02017093 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,01105873 0,02015544 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,01105873 0,02013997 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,01105873 0,02012452 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,01105873 0,0201091 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,01105873 0,0200937 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,01105873 0,02007833 ! adult walking behavior GO:0007628 30 17 0,000 0,01105873 0,02006298 ! patterning of blood vessels GO:0001569 27 17 0,000 0,01105873 0,02004765 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,01105873 0,02003235 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,01105873 0,02001707 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,01105873 0,02000181 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01105873 0,01998658 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,01105873 0,01997137 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,01105873 0,01995618 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,01105873 0,01994102 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01105873 0,01992588 ! protein polyubiquitination GO:0000209 31 17 0,000 0,01105873 0,01991076 ! cerebral cortex development GO:0021987 34 17 0,000 0,01105873 0,01989566 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,01105873 0,01988059 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01105873 0,01986554 ! fructose metabolic process GO:0006000 24 17 0,000 0,01105873 0,01985051 ! membrane budding GO:0006900 30 17 0,000 0,01105873 0,01983551 ! neuromuscular junction development GO:0007528 25 17 0,000 0,01105873 0,01982053 ! L-amino acid transport GO:0015807 27 17 0,000 0,01105873 0,01980557 ! regulation of protein binding GO:0043393 29 17 0,000 0,01105873 0,01979063 ! peptide secretion GO:0002790 30 17 0,000 0,01105873 0,01977572 ! stem cell differentiation GO:0048863 40 17 0,000 0,01105873 0,01976083 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01105873 0,01974596 ! intermediate filament-based process GO:0045103 29 17 0,000 0,01105873 0,01973111 ! protein export from nucleus GO:0006611 26 17 0,000 0,01105873 0,01971629 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,01105873 0,01970148 ! diencephalon development GO:0021536 27 17 0,000 0,01105873 0,0196867 ! oogenesis GO:0048477 25 17 0,000 0,01105873 0,01967195 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,01105873 0,01965721 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,01105873 0,0196425 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01105873 0,01962781 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,01105873 0,01961314 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,01105873 0,01959849 ! steroid catabolic process GO:0006706 24 17 0,000 0,01105873 0,01958386 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,01105873 0,01956926 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,01105873 0,01955468 ! nerve development GO:0021675 20 17 0,000 0,01105873 0,01954012 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,01105873 0,01952558 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,01105873 0,01951106 ! protein secretion GO:0009306 32 18 0,000 0,01170572 0,0206372 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,01170572 0,02062188 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,01170572 0,02060658 ! negative regulation of defense response GO:0031348 21 18 0,000 0,01170572 0,02059131 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,01170572 0,02057605 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,01170572 0,02056082 ! metencephalon development GO:0022037 25 18 0,000 0,01170572 0,02054562 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,01170572 0,02053043 ! hormone secretion GO:0046879 28 18 0,000 0,01170572 0,02051527 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,01170572 0,02050013 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,01170572 0,02048501 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,01170572 0,02046991 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01170572 0,02045484 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,01170572 0,02043979 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,01170572 0,02042476 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01170572 0,02040975 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,01170572 0,02039477 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,01170572 0,0203798 ! glial cell development GO:0021782 31 18 0,000 0,01170572 0,02036486 ! keratinization GO:0031424 19 18 0,000 0,01170572 0,02034994 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,01170572 0,02033505 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,01170572 0,02032017 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,01170572 0,02030532 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,01170572 0,02029048 ! vacuolar transport GO:0007034 26 18 0,000 0,01170572 0,02027567 ! pigmentation during development GO:0048066 35 18 0,000 0,01170572 0,02026088 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,01170572 0,02024612 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,01170572 0,02023137 ! cellular response to unfolded protein GO:0034620 24 18 0,000 0,01170572 0,02021665 GO:0030968|endoplasmic reticulum unfolded protein response, ! fucose metabolic process GO:0006004 27 18 0,000 0,01170572 0,02020194 ! actin filament bundle formation GO:0051017 30 18 0,000 0,01170572 0,02018726 ! body fluid secretion GO:0007589 27 18 0,000 0,01170572 0,0201726 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,01170572 0,02015796 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,01170572 0,02014335 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,01170572 0,02012875 ! negative regulation of immune response GO:0050777 33 18 0,000 0,01170572 0,02011417 ! heart process GO:0003015 32 18 0,000 0,01170572 0,02009962 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,01170572 0,02008509 ! sensory perception of pain GO:0019233 26 18 0,000 0,01170572 0,02007057 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,01170572 0,02005608 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,01170572 0,02004161 ! somitogenesis GO:0001756 25 18 0,000 0,01170572 0,02002716 ! neural crest cell migration GO:0001755 28 18 0,000 0,01170572 0,02001273 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,01170572 0,01999832 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,01170572 0,01998394 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,01170572 0,01996957 ! synaptogenesis GO:0007416 28 18 0,000 0,01170572 0,01995522 ! cell-cell junction organization GO:0045216 28 18 0,000 0,01170572 0,0199409 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01170572 0,01992659 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,01170572 0,01991231 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,01170572 0,01989805 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,01170572 0,0198838 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,01170572 0,01986958 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,01170572 0,01985538 ! gut development GO:0048565 29 18 0,000 0,01170572 0,01984119 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,01170572 0,01982703 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,01170572 0,01981289 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,01170572 0,01979877 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,01235231 0,02087752 ! positive regulation of translation GO:0045727 29 19 0,000 0,01235231 0,02086266 ! positive regulation of cell size GO:0045793 26 19 0,000 0,01235231 0,02084782 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,01235231 0,02083301 ! glycerol metabolic process GO:0006071 22 19 0,000 0,01235231 0,02081821 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,01235231 0,02080344 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,01235231 0,02078868 ! endothelial cell migration GO:0043542 24 19 0,000 0,01235231 0,02077395 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,01235231 0,02075924 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,01235231 0,02074454 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,01235231 0,02072987 ! memory GO:0007613 28 19 0,000 0,01235231 0,02071522 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,01235231 0,02070059 ! pancreas development GO:0031016 27 19 0,000 0,01235231 0,02068598 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,01235231 0,0206714 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,01235231 0,02065683 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,01235231 0,02064228 ! central nervous system neuron development GO:0021954 33 19 0,000 0,01235231 0,02062776 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,01235231 0,02061325 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,01235231 0,02059876 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,01235231 0,0205843 ! heme metabolic process GO:0042168 29 19 0,000 0,01235231 0,02056985 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,01235231 0,02055543 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,01235231 0,02054102 ! response to fungus GO:0009620 21 19 0,000 0,01235231 0,02052664 ! peptide cross-linking GO:0018149 35 19 0,000 0,01235231 0,02051227 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,01235231 0,02049793 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,01235231 0,02048361 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,01235231 0,0204693 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,01235231 0,02045502 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,01235231 0,02044075 ! vitamin transport GO:0051180 26 19 0,000 0,01235231 0,02042651 ! sarcomere organization GO:0045214 26 19 0,000 0,01235231 0,02041228 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,01235231 0,02039808 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,01235231 0,02038389 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,01235231 0,02036973 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,01235231 0,02035558 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,01235231 0,02034146 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,01235231 0,02032735 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,01299852 0,02137594 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,01299852 0,02136114 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,01299852 0,02134635 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,01299852 0,02133159 ! lipid phosphorylation GO:0046834 28 20 0,000 0,01299852 0,02131685 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,01299852 0,02130213 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,01299852 0,02128743 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,01299852 0,02127275 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,01299852 0,02125809 ! response to alkaloid GO:0043279 34 20 0,000 0,01299852 0,02124344 ! sensory perception of taste GO:0050909 26 20 0,000 0,01299852 0,02122882 ! response to retinoic acid GO:0032526 27 20 0,000 0,01299852 0,02121422 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,01299852 0,02119964 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,01299852 0,02118508 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,01299852 0,02117054 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,01299852 0,02115602 ! chromosome condensation GO:0030261 32 20 0,000 0,01299852 0,02114152 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,01299852 0,02112704 ! sex determination GO:0007530 32 20 0,000 0,01299852 0,02111258 ! plasma membrane fusion GO:0045026 24 20 0,000 0,01299852 0,02109814 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,01299852 0,02108372 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,01299852 0,02106932 ! cytolysis GO:0019835 21 20 0,000 0,01299852 0,02105494 ! renal system process GO:0003014 35 20 0,000 0,01299852 0,02104057 ! vasodilation GO:0042311 36 20 0,000 0,01299852 0,02102623 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,01299852 0,02101191 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,01299852 0,02099761 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,01299852 0,02098332 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,01299852 0,02096906 ! hormone transport GO:0009914 30 20 0,000 0,01299852 0,02095481 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,01299852 0,02094059 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,01299852 0,02092638 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,01299852 0,02091219 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,01299852 0,02089802 ! sperm-egg recognition GO:0035036 24 20 0,000 0,01299852 0,02088387 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,01299852 0,02086974 ! negative regulation of translation GO:0017148 28 20 0,000 0,01299852 0,02085563 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,01299852 0,02084154 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,01364433 0,02186225 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,01364433 0,0218475 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,01364433 0,02183277 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01364433 0,02181806 ! positive regulation of ossification GO:0045778 34 21 0,000 0,01364433 0,02180336 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,01364433 0,02178869 ! iron ion transport GO:0006826 49 21 0,000 0,01364433 0,02177404 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,01364433 0,02175941 ! microtubule-based transport GO:0010970 41 21 0,000 0,01364433 0,02174479 ! vesicle docking GO:0048278 28 21 0,000 0,01364433 0,0217302 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,01364433 0,02171563 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,01364433 0,02170107 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,01364433 0,02168654 ! response to ethanol GO:0045471 38 21 0,000 0,01364433 0,02167202 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,01364433 0,02165752 ! smooth muscle contraction GO:0006939 39 21 0,000 0,01364433 0,02164305 ! glutamine metabolic process GO:0006541 29 21 0,000 0,01364433 0,02162859 ! response to vitamin A GO:0033189 28 21 0,000 0,01364433 0,02161415 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,01364433 0,02159973 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,01364433 0,02158533 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,01364433 0,02157095 ! response to starvation GO:0042594 35 21 0,000 0,01364433 0,02155659 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,01364433 0,02154225 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,01364433 0,02152792 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,01364433 0,02151362 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,01364433 0,02149933 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,01364433 0,02148507 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,01364433 0,02147082 ! visual learning GO:0008542 38 21 0,000 0,01364433 0,02145659 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,01364433 0,02144238 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,01364433 0,02142819 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,01364433 0,02141402 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01364433 0,02139987 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,01364433 0,02138573 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,01364433 0,02137162 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01364433 0,02135752 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,01364433 0,02134344 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,01364433 0,02132938 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,01364433 0,02131534 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,01364433 0,02130131 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,01364433 0,02128731 ! embryonic pattern specification GO:0009880 34 22 0,000 0,01428975 0,02227962 ! regulation of cell killing GO:0031341 37 22 0,000 0,01428975 0,02226499 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,01428975 0,02225038 ! gluconeogenesis GO:0006094 26 22 0,000 0,01428975 0,02223579 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,01428975 0,02222122 ! viral genome replication GO:0019079 31 22 0,000 0,01428975 0,02220667 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,01428975 0,02219214 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,01428975 0,02217762 ! protein amino acid acylation GO:0043543 42 22 0,000 0,01428975 0,02216313 ! response to vitamin GO:0033273 31 22 0,000 0,01428975 0,02214865 ! molting cycle process GO:0022404 43 22 0,000 0,01428975 0,02213419 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,01428975 0,02211976 ! regeneration GO:0031099 37 22 0,000 0,01428975 0,02210534 ! phototransduction GO:0007602 29 22 0,000 0,01428975 0,02209094 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,01428975 0,02207655 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,01428975 0,02206219 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,01428975 0,02204785 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,01428975 0,02203352 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,01428975 0,02201921 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,01428975 0,02200492 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,01428975 0,02199065 ! pallium development GO:0021543 43 22 0,000 0,01428975 0,0219764 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,01428975 0,02196217 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,01428975 0,02194795 ! platelet activation GO:0030168 33 22 0,000 0,01428975 0,02193376 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,01428975 0,02191958 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,01428975 0,02190542 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,01428975 0,02189128 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,01428975 0,02187715 ! cell-cell recognition GO:0009988 28 22 0,000 0,01428975 0,02186305 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,01428975 0,02184896 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,01428975 0,02183489 ! neural tube closure GO:0001843 35 22 0,000 0,01428975 0,02182084 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,01428975 0,02180681 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,01428975 0,02179279 ! protein tetramerization GO:0051262 43 22 0,000 0,01428975 0,0217788 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,01493479 0,02274727 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,01493479 0,02273268 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,01493479 0,02271811 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,01493479 0,02270356 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,01493479 0,02268902 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,01493479 0,0226745 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,01493479 0,02266001 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,01493479 0,02264553 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,01493479 0,02263107 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,01493479 0,02261662 ! tube lumen formation GO:0035148 37 23 0,000 0,01493479 0,0226022 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,01493479 0,0225878 ! dendrite development GO:0016358 41 23 0,000 0,01493479 0,02257341 ! vasculogenesis GO:0001570 38 23 0,000 0,01493479 0,02255904 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,01493479 0,02254469 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,01493479 0,02253036 ! lysosome organization GO:0007040 41 23 0,000 0,01493479 0,02251604 ! digestive system process GO:0022600 35 23 0,000 0,01493479 0,02250175 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,01493479 0,02248747 ! vesicle targeting GO:0006903 35 23 0,000 0,01493479 0,02247321 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,01493479 0,02245897 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,01493479 0,02244474 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,01493479 0,02243054 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,01493479 0,02241635 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,01493479 0,02240218 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,01493479 0,02238803 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,01493479 0,0223739 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,01493479 0,02235978 ! membrane depolarization GO:0051899 40 23 0,000 0,01493479 0,02234568 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01493479 0,0223316 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,01493479 0,02231754 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,01493479 0,02230349 ! DNA modification GO:0006304 33 23 0,000 0,01493479 0,02228947 ! collagen fibril organization GO:0030199 50 23 0,000 0,01493479 0,02227546 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,01493479 0,02226146 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,01493479 0,02224749 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,01493479 0,02223353 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,01493479 0,02221959 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,01493479 0,02220567 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,01493479 0,02219177 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01493479 0,02217788 ! collagen catabolic process GO:0030574 29 23 0,000 0,01493479 0,02216401 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,01493479 0,02215016 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,01493479 0,02213632 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,01493479 0,0221225 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,01493479 0,0221087 ! blastocyst development GO:0001824 41 23 0,000 0,01493479 0,02209492 ! actin filament-based movement GO:0030048 37 23 0,000 0,01493479 0,02208115 ! protein stabilization GO:0050821 34 23 0,000 0,01493479 0,0220674 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,01557943 0,02300559 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,01557943 0,02299129 ! myelination GO:0042552 39 24 0,000 0,01557943 0,022977 ! initiation of viral infection GO:0019059 47 24 0,000 0,01557943 0,02296273 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,01557943 0,02294847 ! leukocyte adhesion GO:0007159 49 24 0,000 0,01557943 0,02293424 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,01557943 0,02292002 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,01557943 0,02290582 ! visual behavior GO:0007632 42 24 0,000 0,01557943 0,02289163 ! spinal cord development GO:0021510 41 24 0,000 0,01557943 0,02287747 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,01557943 0,02286332 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,01557943 0,02284919 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,01557943 0,02283508 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,01557943 0,02282098 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,01557943 0,0228069 ! cell aging GO:0007569 38 24 0,000 0,01557943 0,02279284 ! osteoblast differentiation GO:0001649 43 24 0,000 0,01557943 0,0227788 ! response to endoplasmic reticulum stress GO:0034976 32 24 0,000 0,01557943 0,02276477 ! response to toxin GO:0009636 38 24 0,000 0,01557943 0,02275076 ! primary neural tube formation GO:0014020 37 24 0,000 0,01557943 0,02273677 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,01557943 0,0227228 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,01557943 0,02270884 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,01557943 0,0226949 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,01557943 0,02268098 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,01557943 0,02266707 ! pentose metabolic process GO:0019321 33 24 0,000 0,01557943 0,02265318 ! immunoglobulin production GO:0002377 37 24 0,000 0,01557943 0,02263931 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,01557943 0,02262545 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,01557943 0,02261161 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,01557943 0,02259779 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,01557943 0,02258399 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,01557943 0,0225702 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,01557943 0,02255643 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,01557943 0,02254268 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,01557943 0,02252894 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,01622369 0,02344629 ! neuron fate commitment GO:0048663 38 25 0,000 0,01622369 0,02343202 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,01622369 0,02341776 ! superoxide metabolic process GO:0006801 33 25 0,000 0,01622369 0,02340353 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,01622369 0,02338931 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,01622369 0,02337511 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,01622369 0,02336093 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,01622369 0,02334676 ! vacuole organization GO:0007033 43 25 0,000 0,01622369 0,02333261 ! receptor metabolic process GO:0043112 40 25 0,000 0,01622369 0,02331848 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,01622369 0,02330436 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,01622369 0,02329026 ! regulation of behavior GO:0050795 45 25 0,000 0,01622369 0,02327618 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,01622369 0,02326212 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,01622369 0,02324807 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,01622369 0,02323404 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,01622369 0,02322003 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01622369 0,02320603 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,01622369 0,02319205 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,01622369 0,02317809 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,01622369 0,02316414 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,01622369 0,02315021 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,01622369 0,0231363 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,01622369 0,02312241 ! regulation of amine transport GO:0051952 44 25 0,000 0,01622369 0,02310853 ! liver development GO:0001889 44 25 0,000 0,01622369 0,02309466 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,01686755 0,02399682 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,01686755 0,02398244 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,01686755 0,02396808 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,01686755 0,02395374 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,01686755 0,02393941 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,01686755 0,0239251 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,01686755 0,02391081 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,01686755 0,02389654 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,01686755 0,02388228 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,01686755 0,02386804 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,01686755 0,02385381 ! sperm motility GO:0030317 31 26 0,000 0,01686755 0,02383961 ! ER-nuclear signaling pathway GO:0006984 33 26 0,000 0,01686755 0,02382542 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,01686755 0,02381124 ! male gonad development GO:0008584 39 26 0,000 0,01686755 0,02379709 ! neural crest cell development GO:0014032 44 26 0,000 0,01686755 0,02378295 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,01686755 0,02376882 ! cell fate determination GO:0001709 54 26 0,000 0,01686755 0,02375472 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,01686755 0,02374063 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,01686755 0,02372655 ! detection of visible light GO:0009584 33 26 0,000 0,01686755 0,0237125 ! spermatid development GO:0007286 40 26 0,000 0,01686755 0,02369846 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,01686755 0,02368444 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,01686755 0,02367043 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,01686755 0,02365644 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,01686755 0,02364247 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01751103 0,02452991 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,01751103 0,02451544 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,01751103 0,02450098 ! membrane docking GO:0022406 40 27 0,000 0,01751103 0,02448654 ! circadian rhythm GO:0007623 44 27 0,000 0,01751103 0,02447212 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,01751103 0,02445772 ! fat cell differentiation GO:0045444 41 27 0,000 0,01751103 0,02444333 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,01751103 0,02442896 ! autophagy GO:0006914 36 27 0,000 0,01751103 0,02441461 ! myofibril assembly GO:0030239 40 27 0,000 0,01751103 0,02440027 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,01751103 0,02438595 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,01751103 0,02437165 ! peptide transport GO:0015833 46 27 0,000 0,01751103 0,02435737 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,01751103 0,0243431 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,01751103 0,02432884 ! negative regulation of cell development GO:0010721 67 27 0,000 0,01751103 0,02431461 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,01751103 0,02430039 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,01751103 0,02428619 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,01751103 0,024272 ! detection of light stimulus GO:0009583 35 27 0,000 0,01751103 0,02425783 ! glutathione metabolic process GO:0006749 35 27 0,000 0,01751103 0,02424368 ! lipid oxidation GO:0034440 39 27 0,000 0,01751103 0,02422954 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,01751103 0,02421542 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,01751103 0,02420132 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,01751103 0,02418723 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,01815411 0,02506091 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,01815411 0,02504634 ! translational initiation GO:0006413 48 28 0,000 0,01815411 0,02503179 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,01815411 0,02501725 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,01815411 0,02500273 ! regulation of pH GO:0006885 40 28 0,000 0,01815411 0,02498823 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,01815411 0,02497375 ! catechol metabolic process GO:0009712 46 28 0,000 0,01815411 0,02495928 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,01815411 0,02494482 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,01815411 0,02493039 ! iron ion homeostasis GO:0055072 49 28 0,000 0,01815411 0,02491597 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,01815411 0,02490157 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,01815411 0,02488718 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,01815411 0,02487281 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,01815411 0,02485846 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,01815411 0,02484412 ! gene silencing GO:0016458 47 28 0,000 0,01815411 0,02482981 ! regulation of coagulation GO:0050818 42 28 0,000 0,01815411 0,0248155 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,01879681 0,02567924 ! phenol metabolic process GO:0018958 47 29 0,000 0,01879681 0,02566446 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,01879681 0,0256497 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,01879681 0,02563496 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,01879681 0,02562024 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,01879681 0,02560553 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,01879681 0,02559084 ! cholesterol transport GO:0030301 48 29 0,000 0,01879681 0,02557617 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,01879681 0,02556151 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,01879681 0,02554687 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,01879681 0,02553225 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,01879681 0,02551764 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,01879681 0,02550305 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,01879681 0,02548848 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,01879681 0,02547392 ! response to ionizing radiation GO:0010212 55 29 0,000 0,01879681 0,02545938 ! muscle cell development GO:0055001 42 29 0,000 0,01879681 0,02544486 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,01879681 0,02543035 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,01879681 0,02541586 ! mesoderm formation GO:0001707 52 29 0,000 0,01879681 0,02540139 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,01879681 0,02538693 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,01879681 0,02537249 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,01879681 0,02535807 ! ensheathment of neurons GO:0007272 48 29 0,000 0,01879681 0,02534366 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,01879681 0,02532927 ! spermatid differentiation GO:0048515 45 29 0,000 0,01879681 0,02531489 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,01879681 0,02530053 ! neural tube formation GO:0001841 46 29 0,000 0,01879681 0,02528619 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,01943912 0,02613543 ! organic anion transport GO:0015711 50 30 0,000 0,01943912 0,02612063 ! cell junction assembly GO:0034329 65 30 0,000 0,01943912 0,02610585 ! acute-phase response GO:0006953 49 30 0,000 0,01943912 0,02609109 ! segmentation GO:0035282 43 30 0,000 0,01943912 0,02607634 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,01943912 0,0260616 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,01943912 0,02604689 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,01943912 0,02603219 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,01943912 0,02601751 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,01943912 0,02600284 ! ceramide metabolic process GO:0006672 47 30 0,000 0,01943912 0,02598819 ! formation of primary germ layer GO:0001704 54 30 0,000 0,01943912 0,02597356 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,01943912 0,02595894 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,01943912 0,02594434 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,01943912 0,02592976 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,01943912 0,02591519 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,01943912 0,02590064 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,01943912 0,0258861 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,01943912 0,02587159 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,02008105 0,02671094 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,02008105 0,02669598 ! post-embryonic development GO:0009791 50 31 0,000 0,02008105 0,02668103 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,02008105 0,0266661 ! regulation of innate immune response GO:0045088 42 31 0,000 0,02008105 0,02665119 ! ovulation cycle process GO:0022602 46 31 0,000 0,02008105 0,02663629 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,02008105 0,02662141 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,02008105 0,02660654 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,02008105 0,0265917 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,02008105 0,02657687 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,02008105 0,02656205 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,02008105 0,02654725 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,02008105 0,02653247 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,02008105 0,02651771 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,02008105 0,02650296 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,02008105 0,02648823 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,02008105 0,02647351 ! tissue homeostasis GO:0001894 45 31 0,000 0,02008105 0,02645881 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,02072258 0,02728895 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,02072258 0,02727381 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,02072258 0,02725869 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,02072258 0,02724359 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,02072258 0,02722851 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,02072258 0,02721344 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,02072258 0,02719839 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,02072258 0,02718335 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,02072258 0,02716833 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,02072258 0,02715333 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,02072258 0,02713834 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,02072258 0,02712338 ! telencephalon development GO:0021537 59 32 0,000 0,02072258 0,02710842 ! ovulation cycle GO:0042698 48 32 0,000 0,02072258 0,02709349 ! cofactor catabolic process GO:0051187 52 32 0,000 0,02072258 0,02707857 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,02072258 0,02706367 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,02072258 0,02704878 ! placenta development GO:0001890 45 32 0,000 0,02072258 0,02703391 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,02072258 0,02701906 ! vesicle localization GO:0051648 50 32 0,000 0,02072258 0,02700422 ! regulation of muscle development GO:0048634 52 33 0,000 0,02136373 0,02782444 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,02136373 0,02780917 ! negative regulation of secretion GO:0051048 53 33 0,000 0,02136373 0,02779393 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,02136373 0,0277787 ! glial cell differentiation GO:0010001 65 33 0,000 0,02136373 0,02776348 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,02136373 0,02774829 ! sister chromatid segregation GO:0000819 48 33 0,000 0,02136373 0,02773311 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,02136373 0,02771795 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,02136373 0,0277028 ! spindle organization GO:0007051 39 33 0,000 0,02136373 0,02768767 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,02136373 0,02767256 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,02136373 0,02765746 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,02136373 0,02764238 ! protein targeting to membrane GO:0006612 63 33 0,000 0,02136373 0,02762731 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,02136373 0,02761227 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,02136373 0,02759724 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,02136373 0,02758222 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,02136373 0,02756722 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,02136373 0,02755224 ! cytokine production GO:0001816 49 33 0,000 0,02136373 0,02753727 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,02136373 0,02752232 ! RNA modification GO:0009451 43 33 0,000 0,02136373 0,02750739 ! regulation of B cell activation GO:0050864 55 33 0,000 0,02136373 0,02749247 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,02136373 0,02747757 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,02200449 0,02828637 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,02200449 0,02827106 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,02200449 0,02825576 ! actomyosin structure organization GO:0031032 48 34 0,000 0,02200449 0,02824048 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,02200449 0,02822521 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,02200449 0,02820996 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,02200449 0,02819473 ! positive regulation of cell development GO:0010720 58 34 0,000 0,02200449 0,02817952 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,02200449 0,02816432 ! cell fate specification GO:0001708 49 34 0,000 0,02200449 0,02814913 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,02200449 0,02813397 ! peripheral nervous system development GO:0007422 58 34 0,000 0,02200449 0,02811882 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,02200449 0,02810368 ! adult locomotory behavior GO:0008344 54 34 0,000 0,02200449 0,02808857 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,02200449 0,02807346 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,02264486 0,02887493 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,02264486 0,02885942 ! collagen metabolic process GO:0032963 47 35 0,000 0,02264486 0,02884393 ! cell junction organization GO:0034330 72 35 0,000 0,02264486 0,02882846 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,02264486 0,028813 ! metanephros development GO:0001656 61 35 0,000 0,02264486 0,02879756 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,02264486 0,02878213 ! female gonad development GO:0008585 55 35 0,000 0,02264486 0,02876673 ! lipid homeostasis GO:0055088 63 35 0,000 0,02264486 0,02875134 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,02264486 0,02873596 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02264486 0,0287206 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,02264486 0,02870526 ! hindbrain development GO:0030902 56 35 0,000 0,02264486 0,02868993 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,02264486 0,02867462 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,02264486 0,02865933 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,02264486 0,02864405 ! cytokinesis GO:0000910 57 35 0,000 0,02264486 0,02862879 ! embryonic organ development GO:0048568 53 35 0,000 0,02264486 0,02861355 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,02264486 0,02859832 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,02264486 0,02858311 ! protein homooligomerization GO:0051260 59 35 0,000 0,02264486 0,02856791 ! meiosis I GO:0007127 61 36 0,000 0,02328484 0,02935969 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,02328484 0,02934409 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,02328484 0,02932852 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,02328484 0,02931296 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,02328484 0,02929742 ! mismatch repair GO:0006298 42 36 0,000 0,02328484 0,02928189 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,02328484 0,02926638 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,02328484 0,02925089 ! regulation of proteolysis GO:0030162 53 36 0,000 0,02328484 0,02923541 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,02328484 0,02921995 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,02328484 0,02920451 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,02328484 0,02918908 ! eye morphogenesis GO:0048592 64 36 0,000 0,02328484 0,02917367 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,02328484 0,02915827 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,02392444 0,0299434 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,02392444 0,02992762 ! mammary gland development GO:0030879 73 37 0,000 0,02392444 0,02991185 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,02392444 0,0298961 ! ear morphogenesis GO:0042471 50 37 0,000 0,02392444 0,02988037 ! odontogenesis GO:0042476 60 37 0,000 0,02392444 0,02986465 ! negative regulation of binding GO:0051100 59 37 0,000 0,02392444 0,02984895 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,02392444 0,02983326 ! tissue remodeling GO:0048771 65 37 0,000 0,02392444 0,02981759 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,02392444 0,02980194 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,02392444 0,0297863 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,02392444 0,02977068 ! natural killer cell activation GO:0030101 45 37 0,000 0,02392444 0,02975508 ! polyol metabolic process GO:0019751 47 37 0,000 0,02392444 0,02973949 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,02392444 0,02972392 ! glucan metabolic process GO:0044042 54 37 0,000 0,02392444 0,02970837 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,02456365 0,03048616 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,02456365 0,03047023 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,02456365 0,03045431 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,02456365 0,0304384 ! feeding behavior GO:0007631 50 38 0,000 0,02456365 0,03042252 ! organic ether metabolic process GO:0018904 51 38 0,000 0,02456365 0,03040665 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,02456365 0,03039079 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,02456365 0,03037496 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,02456365 0,03035914 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,02456365 0,03034333 ! ion transmembrane transport GO:0034220 58 38 0,000 0,02456365 0,03032755 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,02456365 0,03031177 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,02456365 0,03029602 ! neuron migration GO:0001764 59 38 0,000 0,02456365 0,03028028 ! maintenance of protein location GO:0045185 72 38 0,000 0,02456365 0,03026456 ! pigment metabolic process GO:0042440 66 38 0,000 0,02456365 0,03024885 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,02456365 0,03023317 ! mRNA catabolic process GO:0006402 58 39 0,000 0,02520248 0,03100336 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,02520248 0,03098729 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,02520248 0,03097125 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,02520248 0,03095521 ! neural tube development GO:0021915 58 39 0,000 0,02520248 0,0309392 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,02520248 0,0309232 ! regulation of protein stability GO:0031647 58 39 0,000 0,02520248 0,03090722 ! female gamete generation GO:0007292 50 39 0,000 0,02520248 0,03089126 ! aerobic respiration GO:0009060 56 39 0,000 0,02520248 0,03087531 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,02520248 0,03085938 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,02520248 0,03084346 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,02584091 0,0316085 ! Notch signaling pathway GO:0007219 64 40 0,000 0,02584091 0,03159222 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,02584091 0,03157595 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,02584091 0,0315597 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,02584091 0,03154346 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,02584091 0,03152724 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,02584091 0,03151104 ! phagocytosis GO:0006909 65 40 0,000 0,02584091 0,03149486 ! mesenchymal cell development GO:0014031 70 40 0,000 0,02584091 0,03147869 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,02584091 0,03146254 ! B cell differentiation GO:0030183 70 40 0,000 0,02584091 0,0314464 ! pigmentation GO:0043473 81 40 0,000 0,02584091 0,03143029 ! developmental growth GO:0048589 70 40 0,000 0,02584091 0,03141419 ! synapse organization GO:0050808 61 40 0,000 0,02584091 0,0313981 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,02647897 0,0321569 ! RNA export from nucleus GO:0006405 57 41 0,000 0,02647897 0,03214045 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,02647897 0,03212402 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,02647897 0,03210761 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,02647897 0,03209121 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,02647897 0,03207483 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,02647897 0,03205846 ! cell growth GO:0016049 71 41 0,000 0,02647897 0,03204212 ! maintenance of location in cell GO:0051651 77 41 0,000 0,02647897 0,03202578 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,02711663 0,03278032 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,02711663 0,03276363 ! learning GO:0007612 75 42 0,000 0,02711663 0,03274696 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,02711663 0,0327303 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,02711663 0,03271366 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,02711663 0,03269704 ! gliogenesis GO:0042063 85 42 0,000 0,02711663 0,03268043 ! endosome transport GO:0016197 74 42 0,000 0,02711663 0,03266384 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,02711663 0,03264727 ! male sex differentiation GO:0046661 62 42 0,000 0,02711663 0,03263072 ! double-strand break repair GO:0006302 75 42 0,000 0,02711663 0,03261418 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,02711663 0,03259766 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,02711663 0,03258115 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,02711663 0,03256466 ! mitochondrial transport GO:0006839 66 43 0,000 0,02775391 0,03331312 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,02775391 0,03329628 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,02775391 0,03327945 ! response to calcium ion GO:0051592 65 43 0,000 0,02775391 0,03326265 ! regulation of tube size GO:0035150 69 43 0,000 0,02775391 0,03324586 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,02775391 0,03322908 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,02775391 0,03321232 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,02775391 0,03319558 ! T cell differentiation GO:0030217 78 43 0,000 0,02775391 0,03317886 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,02775391 0,03316216 ! amino acid activation GO:0043038 61 43 0,000 0,02775391 0,03314547 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,02775391 0,03312879 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 0,000 0,02839081 0,03387199 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,02839081 0,03385497 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,02839081 0,03383797 ! cellular component disassembly GO:0022411 66 44 0,000 0,02839081 0,03382098 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,02839081 0,03380401 ! peptide metabolic process GO:0006518 64 44 0,000 0,02839081 0,03378706 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,02839081 0,03377012 ! inner ear development GO:0048839 66 44 0,000 0,02839081 0,0337532 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,02839081 0,0337363 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,02839081 0,03371942 ! chromatin remodeling GO:0006338 73 44 0,000 0,02839081 0,03370255 ! biopolymer methylation GO:0043414 67 44 0,000 0,02839081 0,0336857 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,02839081 0,03366886 ! JNK cascade GO:0007254 66 44 0,000 0,02839081 0,03365204 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,02839081 0,03363524 ! regulation of cell shape GO:0008360 83 44 0,000 0,02839081 0,03361846 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,02902732 0,03435503 ! positive regulation of binding GO:0051099 67 45 0,000 0,02902732 0,0343379 ! positive regulation of cell cycle GO:0045787 83 45 0,000 0,02902732 0,03432079 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,02902732 0,0343037 ! regulation of ion transport GO:0043269 60 45 0,000 0,02902732 0,03428663 ! glucose transport GO:0015758 60 45 0,000 0,02902732 0,03426957 ! neuromuscular process GO:0050905 89 45 0,000 0,02902732 0,03425253 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,02902732 0,0342355 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,02902732 0,0342185 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,02902732 0,03420151 ! response to insulin stimulus GO:0032868 71 45 0,000 0,02902732 0,03418453 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,02966345 0,03491635 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,02966345 0,03489904 ! regulation of action potential GO:0001508 80 46 0,000 0,02966345 0,03488174 ! hexose transport GO:0008645 62 46 0,000 0,02966345 0,03486447 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,02966345 0,03484721 ! excretion GO:0007588 72 46 0,000 0,02966345 0,03482997 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,02966345 0,03481274 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,02966345 0,03479553 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,02966345 0,03477834 ! positive regulation of defense response GO:0031349 70 47 0,000 0,03029919 0,03550616 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,03029919 0,03548863 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,03029919 0,03547113 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,03029919 0,03545364 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,03029919 0,03543616 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,03029919 0,03541871 ! response to UV GO:0009411 79 47 0,000 0,03029919 0,03540127 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,03093455 0,03612582 ! viral infectious cycle GO:0019058 80 48 0,000 0,03093455 0,03610805 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,03093455 0,0360903 ! leukocyte migration GO:0050900 76 48 0,000 0,03093455 0,03607257 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,03093455 0,03605485 ! striated muscle contraction GO:0006941 78 48 0,000 0,03093455 0,03603715 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,03093455 0,03601947 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,03093455 0,0360018 ! tRNA processing GO:0008033 56 48 0,000 0,03093455 0,03598415 ! cell maturation GO:0048469 69 48 0,000 0,03093455 0,03596652 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,03093455 0,03594891 ! vesicle organization GO:0016050 87 48 0,000 0,03093455 0,03593131 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,03093455 0,03591374 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,03156952 0,03663299 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,03156952 0,03661509 ! glycolysis GO:0006096 63 49 0,000 0,03156952 0,0365972 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,03156952 0,03657933 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,03156952 0,03656148 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,03156952 0,03654364 ! endocrine system development GO:0035270 86 49 0,000 0,03156952 0,03652582 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03156952 0,03650802 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,03156952 0,03649024 ! gastrulation GO:0007369 80 49 0,000 0,03156952 0,03647248 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,03156952 0,03645473 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,03156952 0,036437 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,03156952 0,03641928 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,03156952 0,03640159 ! methylation GO:0032259 74 49 0,000 0,03156952 0,03638391 ! cell redox homeostasis GO:0045454 72 50 0,000 0,03220411 0,03709725 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,03220411 0,03707925 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,03220411 0,03706127 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,03220411 0,03704331 ! histone modification GO:0016570 81 50 0,000 0,03220411 0,03702536 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,03220411 0,03700743 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,03220411 0,03698952 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,03220411 0,03697162 ! RNA catabolic process GO:0006401 77 51 0,000 0,03283831 0,03768148 ! chloride transport GO:0006821 78 51 0,000 0,03283831 0,03766327 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,03283831 0,03764508 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,03283831 0,0376269 ! regulation of ossification GO:0030278 82 51 0,000 0,03283831 0,03760874 ! heart morphogenesis GO:0003007 71 51 0,000 0,03283831 0,0375906 ! RNA elongation GO:0006354 67 51 0,000 0,03283831 0,03757247 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,03283831 0,03755437 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,03347213 0,03826077 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,03347213 0,03824235 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,03347213 0,03822395 ! regulation of DNA replication GO:0006275 88 52 0,000 0,03347213 0,03820556 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,03347213 0,0381872 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,03347213 0,03816884 ! covalent chromatin modification GO:0016569 90 52 0,000 0,03347213 0,03815051 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,03347213 0,0381322 ! proton transport GO:0015992 78 52 0,000 0,03347213 0,0381139 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,03347213 0,03809562 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,03347213 0,03807736 ! transition metal ion transport GO:0000041 88 53 0,000 0,03410557 0,03877935 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 0,000 0,03410557 0,03876078 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,03410557 0,03874223 ! muscle fiber development GO:0048747 80 53 0,000 0,03410557 0,03872369 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,03410557 0,03870517 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,03410557 0,03868667 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,03410557 0,03866819 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,03410557 0,03864972 ! regulation of endocytosis GO:0030100 71 53 0,000 0,03410557 0,03863127 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,03410557 0,03861284 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,03410557 0,03859443 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,03410557 0,03857603 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,03410557 0,03855765 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,03410557 0,03853929 ! hydrogen transport GO:0006818 81 54 0,000 0,03473862 0,03923596 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,03473862 0,03921729 ! regulation of mitosis GO:0007088 91 54 0,000 0,03473862 0,03919864 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,03473862 0,03918001 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,03473862 0,0391614 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,03473862 0,03914281 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,03473862 0,03912423 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,03473862 0,03910567 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,03473862 0,03908713 ! germ cell development GO:0007281 82 54 0,000 0,03473862 0,0390686 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,03473862 0,03905009 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,03473862 0,03903161 ! establishment of organelle localization GO:0051656 91 54 0,000 0,03473862 0,03901313 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,03537129 0,03970486 ! ear development GO:0043583 83 55 0,000 0,03537129 0,03968609 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,03537129 0,03966733 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,03537129 0,0396486 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,03537129 0,03962988 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,03537129 0,03961117 ! regulation of actin filament length GO:0030832 88 56 0,000 0,03600358 0,04030024 ! positive regulation of secretion GO:0051047 83 56 0,000 0,03600358 0,04028123 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,03600358 0,04026225 ! DNA catabolic process GO:0006308 71 56 0,000 0,03600358 0,04024329 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,03600358 0,04022434 ! adult behavior GO:0030534 90 56 0,000 0,03600358 0,04020541 ! cartilage development GO:0051216 84 56 0,000 0,03600358 0,0401865 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,03663549 0,0408726 ! mesoderm development GO:0007498 84 57 0,000 0,03663549 0,04085339 ! aging GO:0007568 91 57 0,000 0,03663549 0,0408342 ! nuclear export GO:0051168 85 57 0,000 0,03663549 0,04081503 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,03663549 0,04079588 ! single fertilization GO:0007338 67 57 0,000 0,03663549 0,04077674 ! regulation of cellular component size GO:0032535 90 58 0,000 0,03726701 0,0414602 ! lipid modification GO:0030258 82 58 0,000 0,03726701 0,04144078 ! positive regulation of growth GO:0045927 78 58 0,000 0,03726701 0,04142137 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,03726701 0,04140197 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,03726701 0,0413826 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,03726701 0,04136324 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,03789815 0,04204409 ! viral reproductive process GO:0022415 99 59 0,000 0,03789815 0,04202445 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,03789815 0,04200482 ! chromosome segregation GO:0007059 93 59 0,000 0,03789815 0,04198521 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,03789815 0,04196562 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,03789815 0,04194604 ! cell projection assembly GO:0030031 90 59 0,000 0,03789815 0,04192649 ! glucose catabolic process GO:0006007 78 60 0,000 0,03852891 0,04260443 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,03852891 0,04258459 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,03852891 0,04256476 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,03852891 0,04254495 ! kidney development GO:0001822 101 60 0,000 0,03852891 0,04252517 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,03852891 0,0425054 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,03915929 0,04318076 ! carbohydrate transport GO:0008643 83 61 0,000 0,03915929 0,0431607 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,03915929 0,04314066 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,03978928 0,04381437 ! amino acid transport GO:0006865 97 62 0,000 0,03978928 0,04379405 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,03978928 0,04377375 ! activation of MAPK activity GO:0000187 95 62 0,000 0,03978928 0,04375346 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,03978928 0,0437332 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,03978928 0,04371295 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,03978928 0,04369272 ! detection of external stimulus GO:0009581 78 62 0,000 0,03978928 0,04367251 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,03978928 0,04365232 ! secondary metabolic process GO:0019748 95 62 0,000 0,03978928 0,04363215 ! gonad development GO:0008406 91 62 0,000 0,03978928 0,043612 ! exocytosis GO:0006887 91 63 0,000 0,0404189 0,04428165 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,0404189 0,04426121 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,0404189 0,0442408 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,0404189 0,0442204 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,0404189 0,04420002 ! regulation of heart contraction GO:0008016 104 63 0,000 0,0404189 0,04417966 ! developmental maturation GO:0021700 90 63 0,000 0,0404189 0,04415932 ! actin filament organization GO:0007015 107 64 0,000 0,04104813 0,04482615 ! fertilization GO:0009566 79 64 0,000 0,04104813 0,04480553 ! viral reproduction GO:0016032 104 64 0,000 0,04104813 0,04478493 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,04104813 0,04476435 ! amine catabolic process GO:0009310 100 65 0,000 0,04167698 0,04542925 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,04167698 0,0454084 ! camera-type eye development GO:0043010 103 65 0,000 0,04167698 0,04538756 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,04167698 0,04536674 ! regulation of lipase activity GO:0060191 117 65 0,000 0,04167698 0,04534594 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,04167698 0,04532515 ! organelle localization GO:0051640 105 65 0,000 0,04167698 0,04530439 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,04230546 0,04596651 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,04230546 0,04594547 ! sensory perception of smell GO:0007608 81 66 0,000 0,04230546 0,04592445 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,04230546 0,04590345 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,04230546 0,04588247 ! lung development GO:0030324 112 66 0,000 0,04230546 0,04586151 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,04230546 0,04584057 ! B cell activation GO:0042113 119 66 0,000 0,04230546 0,04581965 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 0,000 0,04230546 0,04579875 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,04230546 0,04577786 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 0,000 0,04230546 0,045757 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,04293355 0,04641518 ! negative regulation of cell size GO:0045792 125 67 0,000 0,04293355 0,04639404 ! neurotransmitter transport GO:0006836 92 67 0,000 0,04293355 0,04637292 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,04293355 0,04635182 ! appendage morphogenesis GO:0035107 103 67 0,000 0,04293355 0,04633075 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,04293355 0,04630969 ! extracellular matrix organization GO:0030198 117 67 0,000 0,04293355 0,04628865 ! negative regulation of ligase activity GO:0051352 100 67 0,000 0,04293355 0,04626762 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiosis GO:0007126 110 68 0,000 0,04356126 0,04692277 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 0,000 0,04356126 0,04690148 ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,04356126 0,04688021 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 0,000 0,04356126 0,04685896 ! defense response to bacterium GO:0042742 79 68 0,000 0,04356126 0,04683773 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,04356126 0,04681652 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,04356126 0,04679532 ! activation of immune response GO:0002253 93 68 0,000 0,04356126 0,04677415 ! appendage development GO:0048736 108 69 0,000 0,04418859 0,04742629 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,04418859 0,04740485 ! urogenital system development GO:0001655 114 69 0,000 0,04418859 0,04738343 ! meiotic cell cycle GO:0051321 111 69 0,000 0,04418859 0,04736203 ! regulation of endopeptidase activity GO:0052548 106 70 0,000 0,04481554 0,04801232 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 0,000 0,04481554 0,04799065 ! hexose catabolic process GO:0019320 95 70 0,000 0,04481554 0,047969 ! adaptive immune response GO:0002250 102 70 0,000 0,04481554 0,04794738 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,04544211 0,04859583 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,04544211 0,04857394 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,04544211 0,04855206 ! axon guidance GO:0007411 116 71 0,000 0,04544211 0,04853021 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,04544211 0,04850838 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,04606831 0,04915472 ! response to drug GO:0042493 115 72 0,000 0,04606831 0,04913262 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,04606831 0,04911055 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,04606831 0,0490885 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,04606831 0,04906647 ! respiratory system development GO:0060541 123 72 0,000 0,04606831 0,04904446 ! rhythmic process GO:0048511 113 72 0,000 0,04606831 0,04902246 ! regulation of immune effector process GO:0002697 121 72 0,000 0,04606831 0,04900049 ! learning or memory GO:0007611 132 73 0,000 0,04669412 0,04964388 ! humoral immune response GO:0006959 93 73 0,000 0,04669412 0,04962165 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 0,000 0,04669412 0,04959944 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 0,000 0,04669412 0,04957725 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,04669412 0,04955507 ! acute inflammatory response GO:0002526 107 74 0,000 0,04731955 0,05019638 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,04731955 0,05017395 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,04731955 0,05015154 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,04731955 0,05012915 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,04731955 0,05010678 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,04731955 0,05008443 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,04731955 0,0500621 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,04731955 0,05003979 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,04794461 0,0506782 ! regulation of peptidase activity GO:0052547 113 75 0,000 0,04794461 0,05065563 ! positive regulation of phosphorylation GO:0042327 119 75 0,000 0,04794461 0,05063309 ! inorganic anion transport GO:0015698 109 75 0,000 0,04794461 0,05061057 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,04794461 0,05058806 ! regulation of catabolic process GO:0009894 114 75 0,000 0,04794461 0,05056558 ! response to metal ion GO:0010038 114 76 0,000 0,04856929 0,05120165 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,04856929 0,05117891 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,04856929 0,0511562 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,04856929 0,0511335 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,04856929 0,05111083 ! positive regulation of ligase activity GO:0051351 114 76 0,000 0,04856929 0,05108817 ! negative regulation of transport GO:0051051 122 77 0,000 0,04919358 0,05172192 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,04919358 0,05169901 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 0,000 0,04919358 0,05167613 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 114 77 0,000 0,04919358 0,05165326 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,04919358 0,05163042 ! regulation of blood pressure GO:0008217 119 78 0,000 0,0498175 0,05226213 ! muscle cell differentiation GO:0042692 117 78 0,000 0,0498175 0,05223904 ! mitochondrion organization GO:0007005 127 78 0,000 0,0498175 0,05221596 ! negative regulation of growth GO:0045926 140 78 0,000 0,0498175 0,05219291 ! amine transport GO:0015837 115 78 0,000 0,0498175 0,05216987 ! antigen processing and presentation GO:0019882 114 78 0,000 0,0498175 0,05214686 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 0,000 0,05044105 0,05277628 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,05044105 0,05275302 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,05106421 0,05338122 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,05106421 0,05335772 ! regulation of DNA binding GO:0051101 130 80 0,000 0,05106421 0,05333423 ! tube morphogenesis GO:0035239 140 80 0,000 0,05106421 0,05331077 ! eye development GO:0001654 130 80 0,000 0,05106421 0,05328732 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,05106421 0,0532639 ! protein ubiquitination GO:0016567 135 80 0,000 0,05106421 0,0532405 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,05106421 0,05321712 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,05106421 0,05319375 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,05106421 0,05317041 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,05106421 0,05314709 ! blood coagulation GO:0007596 129 81 0,000 0,051687 0,0537717 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,051687 0,05374814 ! response to inorganic substance GO:0010035 127 81 0,000 0,051687 0,05372459 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,051687 0,05370107 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,051687 0,05367757 ! response to hypoxia GO:0001666 155 81 0,000 0,051687 0,05365409 ! regulation of protein transport GO:0051223 123 81 0,000 0,051687 0,05363063 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,05230941 0,05425272 ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,05230941 0,05422902 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,05230941 0,05420534 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,05230941 0,05418168 ! regulation of ligase activity GO:0051340 129 82 0,000 0,05230941 0,05415804 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,05293144 0,05477815 ! positive regulation of protein modification process GO:0031401 126 83 0,000 0,05293144 0,05475428 ! response to oxygen levels GO:0070482 160 83 0,000 0,05293144 0,05473042 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,05293144 0,05470658 ! regulation of lyase activity GO:0051339 147 83 0,000 0,05293144 0,05468276 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,05293144 0,05465897 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,05293144 0,05463519 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,0535531 0,05525282 ! digestion GO:0007586 111 84 0,000 0,0535531 0,05522881 ! regulation of neurological system process GO:0031644 133 84 0,000 0,0535531 0,05520482 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,0535531 0,05518085 ! cellular respiration GO:0045333 119 85 0,000 0,05417437 0,05579678 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,05417437 0,05577258 ! T cell activation GO:0042110 154 85 0,000 0,05417437 0,05574839 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 0,000 0,05417437 0,05572423 GO:0010498|proteasomal protein catabolic process, ! sex differentiation GO:0007548 126 85 0,000 0,05417437 0,05570008 ! protein import into nucleus GO:0006606 145 85 0,000 0,05417437 0,05567596 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,05417437 0,05565186 ! alcohol catabolic process GO:0046164 119 86 0,000 0,05479528 0,05626534 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,05479528 0,056241 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,0554158 0,05685331 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,0554158 0,05682874 ! regulation of defense response GO:0031347 135 87 0,000 0,0554158 0,05680419 ! Golgi vesicle transport GO:0048193 145 87 0,000 0,0554158 0,05677966 ! tRNA metabolic process GO:0006399 110 87 0,000 0,0554158 0,05675516 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,0554158 0,05673067 ! gland development GO:0048732 170 87 0,000 0,0554158 0,05670621 ! interphase of mitotic cell cycle GO:0051329 166 87 0,000 0,0554158 0,05668177 ! vitamin metabolic process GO:0006766 117 87 0,000 0,0554158 0,05665735 ! forebrain development GO:0030900 151 87 0,000 0,0554158 0,05663295 ! regulation of membrane potential GO:0042391 144 88 0,000 0,05603595 0,05724207 ! ossification GO:0001503 150 89 0,000 0,05665573 0,05785028 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,05665573 0,05782539 GO:0031497|chromatin assembly, ! interphase GO:0051325 169 89 0,000 0,05665573 0,05780053 ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,05727513 0,05840734 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,05727513 0,05838225 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,05727513 0,05835718 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,05727513 0,05833214 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,05727513 0,05830711 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,05727513 0,05828211 ! nuclear import GO:0051170 153 90 0,000 0,05727513 0,05825713 ! regulation of protein localization GO:0032880 141 90 0,000 0,05727513 0,05823217 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,05727513 0,05820723 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,05789415 0,05881114 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,05789415 0,05878597 ! protein localization in nucleus GO:0034504 161 92 0,000 0,0585128 0,05938874 ! sterol metabolic process GO:0016125 136 92 0,000 0,0585128 0,05936335 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,05913107 0,05996497 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cell cycle arrest GO:0007050 171 93 0,000 0,05913107 0,05993936 ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,05913107 0,05991376 ! rRNA processing GO:0006364 124 93 0,000 0,05913107 0,05988819 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,05913107 0,05986264 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,05913107 0,05983711 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,05913107 0,05981161 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,05913107 0,05978612 ! leukocyte differentiation GO:0002521 165 94 0,000 0,05974897 0,06038514 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,05974897 0,06035943 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,05974897 0,06033375 ! rRNA metabolic process GO:0016072 125 94 0,000 0,05974897 0,06030808 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,05974897 0,06028244 ! hormone metabolic process GO:0042445 135 94 0,000 0,05974897 0,06025682 ! protein processing GO:0016485 127 94 0,000 0,05974897 0,06023123 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,06036649 0,06082789 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,06036649 0,06080207 ! ATP metabolic process GO:0046034 150 96 0,000 0,06098364 0,06139762 ! nucleosome organization GO:0034728 126 96 0,000 0,06098364 0,06137158 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,06098364 0,06134556 ! female pregnancy GO:0007565 148 96 0,000 0,06098364 0,06131957 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,06160042 0,06191351 ! reproductive developmental process GO:0003006 149 97 0,000 0,06160042 0,0618873 ! response to virus GO:0009615 141 98 0,000 0,06221682 0,06248011 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,06221682 0,06245368 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,06221682 0,06242728 ! regulation of T cell activation GO:0050863 155 98 0,000 0,06221682 0,06240089 ! regulation of binding GO:0051098 164 99 0,000 0,06283285 0,06299212 ! electron transport chain GO:0022900 135 99 0,000 0,06283285 0,06296552 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,06283285 0,06293894 ! cell fate commitment GO:0045165 165 99 0,000 0,06283285 0,06291238 ! positive regulation of immune response GO:0050778 143 99 0,000 0,06283285 0,06288585 ! sulfur metabolic process GO:0006790 136 99 0,000 0,06283285 0,06285934 ! carbohydrate catabolic process GO:0016052 137 100 0,000 0,0634485 0,0634485