pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5717-7-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycolysis GO:0006096 63 49 6,000 2,237E-13 5,307E-10 ! glucose catabolic process GO:0006007 78 60 6,000 9,963E-13 1,182E-09 ! hexose catabolic process GO:0019320 95 70 6,000 3,067E-12 2,426E-09 ! monosaccharide catabolic process GO:0046365 104 77 6,000 6,116E-12 3,628E-09 ! alcohol catabolic process GO:0046164 119 86 6,000 1,356E-11 6,437E-09 ! carbohydrate catabolic process GO:0016052 137 100 6,000 3,993E-11 1,579E-08 ! detection of mechanical stimulus GO:0050982 17 13 3,000 1,627E-09 5,516E-07 ! cartilage condensation GO:0001502 22 14 3,000 2,276E-09 6,752E-07 ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 1,98E-08 5,221E-06 ! response to mechanical stimulus GO:0009612 46 34 3,000 1,036E-07 2,459E-05 ! substrate-bound cell migration GO:0006929 11 10 2,000 2,366E-07 5,103E-05 ! JAK-STAT cascade GO:0007259 62 44 3,000 3,006E-07 5,944E-05 ! detection of abiotic stimulus GO:0009582 66 48 3,000 4,293E-07 7,837E-05 ! cartilage development GO:0051216 84 56 3,000 8,047E-07 1,364E-04 ! skeletal system morphogenesis GO:0048705 90 59 3,000 9,945E-07 1,573E-04 ! detection of external stimulus GO:0009581 78 62 3,000 1,216E-06 1,803E-04 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 3,000 1,565E-06 2,185E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 3,000 1,984E-06 2,616E-04 ! cell-matrix adhesion GO:0007160 133 71 3,000 2,101E-06 2,624E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 3,000 2,349E-06 2,787E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 3,000 2,349E-06 2,654E-04 ! cell-substrate adhesion GO:0031589 141 76 3,000 2,761E-06 2,979E-04 ! positive regulation of ligase activity GO:0051351 114 76 3,000 2,761E-06 2,849E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 3,000 3,225E-06 3,189E-04 ! neuropeptide signaling pathway GO:0007218 101 82 3,000 3,745E-06 3,555E-04 ! regulation of ligase activity GO:0051340 129 82 3,000 3,745E-06 3,418E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 3,000 4,324E-06 3,8E-04 GO:0010498|proteasomal protein catabolic process, ! detection of stimulus GO:0051606 123 91 3,000 5,677E-06 4,811E-04 ! cell cycle arrest GO:0007050 171 93 3,000 6,191E-06 5,066E-04 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 1,639E-05 1,297E-03 ! positive regulation of Rho GTPase activity GO:0032321 12 6 1,000 2,457E-05 1,881E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,437E-05 2,549E-03 ! regulation of focal adhesion formation GO:0051893 17 8 1,000 4,579E-05 3,293E-03 ! cell projection assembly GO:0030031 90 59 2,000 6,142E-05 4,287E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 1,000 7,348E-05 4,982E-03 ! regulation of stress fiber formation GO:0051492 24 10 1,000 7,348E-05 4,844E-03 ! positive regulation of Ras GTPase activity GO:0032320 24 10 1,000 7,348E-05 4,713E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 2,000 8,594E-05 5,366E-03 ! regulation of phosphatase activity GO:0010921 23 11 1,000 8,974E-05 5,46E-03 ! regulation of actin filament bundle formation GO:0032231 25 11 1,000 8,974E-05 5,324E-03 ! negative regulation of ligase activity GO:0051352 100 67 2,000 8,989E-05 5,202E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! axon guidance GO:0007411 116 71 2,000 1,069E-04 6,038E-03 ! phosphate transport GO:0006817 15 12 1,000 1,076E-04 5,938E-03 ! positive regulation of GTPase activity GO:0043547 29 12 1,000 1,076E-04 5,803E-03 ! regulation of Rho GTPase activity GO:0032319 22 12 1,000 1,076E-04 5,674E-03 ! regulation of Ras GTPase activity GO:0032318 125 76 2,000 1,309E-04 6,752E-03 ! regulation of protein ubiquitination GO:0031396 20 14 1,000 1,481E-04 7,478E-03 ! response to unfolded protein GO:0006986 113 80 2,000 1,524E-04 7,536E-03 ! glycoprotein catabolic process GO:0006516 26 15 1,000 1,708E-04 8,27E-03 ! response to protein stimulus GO:0051789 127 85 2,000 1,825E-04 8,659E-03 ! regulation of GTPase activity GO:0043087 149 90 2,000 2,161E-04 0,01005409 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 2,482E-04 0,01132787 ! cellular response to unfolded protein GO:0034620 24 18 1,000 2,482E-04 0,01111414 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 38 18 1,000 2,482E-04 0,01090832 ! negative regulation of translation GO:0017148 28 20 1,000 3,078E-04 0,01327861 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 4,456E-04 0,01888367 ! regulation of cell-matrix adhesion GO:0001952 57 25 1,000 4,84E-04 0,02014942 GO:0010810|regulation of cell-substrate adhesion, ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 5,239E-04 0,02143495 ! fat cell differentiation GO:0045444 41 27 1,000 5,654E-04 0,0227391 ! negative regulation of protein modification process GO:0031400 56 28 1,000 6,084E-04 0,02406078 ! positive regulation of cell adhesion GO:0045785 54 29 1,000 6,529E-04 0,02539898 ! regulation of Rab protein signal transduction GO:0032483 58 38 1,000 1,122E-03 0,04295798 GO:0032313|regulation of Rab GTPase activity, ! RNA export from nucleus GO:0006405 57 41 1,000 1,306E-03 0,04919345 ! response to calcium ion GO:0051592 65 43 1,000 1,436E-03 0,05324078 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 1,000 1,503E-03 0,05487389 ! positive regulation of cell cycle GO:0045787 83 45 1,000 1,572E-03 0,05651068 ! response to insulin stimulus GO:0032868 71 45 1,000 1,572E-03 0,05566724 ! response to UV GO:0009411 79 47 1,000 1,713E-03 0,05979418 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 1,000 2,174E-03 0,07475688 ! cytokine-mediated signaling pathway GO:0019221 77 53 1,000 2,174E-03 0,07368892 ! regulation of protein catabolic process GO:0042176 83 55 1,000 2,339E-03 0,0781668 ! nuclear export GO:0051168 85 57 1,000 2,51E-03 0,08270997 ! chromosome segregation GO:0007059 93 59 1,000 2,686E-03 0,08731482 ! response to peptide hormone stimulus GO:0043434 97 60 1,000 2,776E-03 0,08903362 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 3,55E-03 0,11233612 ! regulation of actin cytoskeleton organization GO:0032956 120 72 1,000 3,971E-03 0,12398866 ! regulation of actin filament-based process GO:0032970 122 74 1,000 4,19E-03 0,12911378 ! regulation of Rho protein signal transduction GO:0035023 126 74 1,000 4,19E-03 0,12745848 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 4,301E-03 0,12918934 ! inorganic anion transport GO:0015698 109 75 1,000 4,301E-03 0,12757447 ! regulation of catabolic process GO:0009894 114 75 1,000 4,301E-03 0,12599948 ! response to metal ion GO:0010038 114 76 1,000 4,414E-03 0,1277244 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 4,528E-03 0,12944676 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 115 80 1,000 4,878E-03 0,13780315 ! response to inorganic substance GO:0010035 127 81 1,000 4,997E-03 0,1395178 ! positive regulation of protein modification process GO:0031401 126 83 1,000 5,24E-03 0,14460106 ! Golgi vesicle transport GO:0048193 145 87 1,000 5,743E-03 0,15663383 ! interphase of mitotic cell cycle GO:0051329 166 87 1,000 5,743E-03 0,1548539 ! interphase GO:0051325 169 89 1,000 6,002E-03 0,16002008 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,52E-03 0,17191569 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 6,52E-03 0,1700265 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 6,52E-03 0,16817839 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,52E-03 0,16637002 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 6,52E-03 0,16460013 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,52E-03 0,16286749 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 6,52E-03 0,16117096 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,52E-03 0,1595094 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 6,52E-03 0,15788175 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 6,52E-03 0,15628699 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,52E-03 0,15472412 ! response to oxygen radical GO:0000305 11 5 0,000 6,52E-03 0,1531922 ! negative regulation of bone resorption GO:0045779 11 5 0,000 6,52E-03 0,15169031 ! myoblast cell fate commitment GO:0048625 8 5 0,000 6,52E-03 0,15021759 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,52E-03 0,14877319 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 6,52E-03 0,1473563 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,52E-03 0,14596615 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 6,52E-03 0,14460198 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 6,52E-03 0,14326307 ! female meiosis GO:0007143 8 5 0,000 6,52E-03 0,14194873 ! nose development GO:0043584 10 5 0,000 6,52E-03 0,14065829 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 6,52E-03 0,1393911 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 6,52E-03 0,13814654 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,52E-03 0,136924 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 6,52E-03 0,13572291 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 6,52E-03 0,13454271 ! cobalt ion transport GO:0006824 9 5 0,000 6,52E-03 0,13338286 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,52E-03 0,13224284 ! SMAD protein complex assembly GO:0007183 10 5 0,000 6,52E-03 0,13112213 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 6,52E-03 0,13002027 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,52E-03 0,12893677 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,52E-03 0,12787117 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,52E-03 0,12682305 ! adaptation of signaling pathway GO:0022401 9 5 0,000 6,52E-03 0,12579197 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 6,52E-03 0,12477752 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,52E-03 0,1237793 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 6,52E-03 0,12279692 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,52E-03 0,12183002 ! negative regulation of histone modification GO:0031057 7 5 0,000 6,52E-03 0,12087822 ! malate metabolic process GO:0006108 8 5 0,000 6,52E-03 0,11994118 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,52E-03 0,11901855 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 6,52E-03 0,11811001 ! clathrin coat assembly GO:0048268 11 5 0,000 6,52E-03 0,11721524 ! Notch receptor processing GO:0007220 8 5 0,000 6,52E-03 0,11633392 ! phototransduction, visible light GO:0007603 7 5 0,000 6,52E-03 0,11546576 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,52E-03 0,11461046 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,52E-03 0,11376773 ! mating behavior GO:0007617 6 5 0,000 6,52E-03 0,11293731 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,52E-03 0,11211893 ! copulation GO:0007620 8 5 0,000 6,52E-03 0,11131232 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,52E-03 0,11051723 ! embryonic hemopoiesis GO:0035162 13 5 0,000 6,52E-03 0,10973342 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,52E-03 0,10896065 ! apoptotic cell clearance GO:0043277 14 5 0,000 6,52E-03 0,10819868 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 6,52E-03 0,10744731 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,52E-03 0,10670629 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 6,52E-03 0,10597542 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 6,52E-03 0,1052545 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,52E-03 0,10454332 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 6,52E-03 0,10384169 ! response to axon injury GO:0048678 8 5 0,000 6,52E-03 0,10314941 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,52E-03 0,1024663 ! response to protozoan GO:0001562 10 5 0,000 6,52E-03 0,10179218 ! negative regulation of heart contraction GO:0045822 12 5 0,000 6,52E-03 0,10112688 ! lymph vessel development GO:0001945 8 5 0,000 6,52E-03 0,10047021 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 6,52E-03 0,09982201 ! endochondral ossification GO:0001958 13 5 0,000 6,52E-03 0,09918213 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,52E-03 0,09855039 ! single strand break repair GO:0000012 5 5 0,000 6,52E-03 0,09792666 ! parathyroid gland development GO:0060017 8 5 0,000 6,52E-03 0,09731077 ! anagen GO:0042640 7 5 0,000 6,52E-03 0,09670257 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,52E-03 0,09610194 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,52E-03 0,09550872 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,52E-03 0,09492277 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 6,52E-03 0,09434398 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 6,52E-03 0,09377219 ! smooth muscle tissue development GO:0048745 14 5 0,000 6,52E-03 0,0932073 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,52E-03 0,09264917 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,52E-03 0,09209769 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,52E-03 0,09155273 ! cardiac muscle fiber development GO:0048739 8 5 0,000 6,52E-03 0,09101419 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,52E-03 0,09048194 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 6,52E-03 0,08995588 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,52E-03 0,08943591 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,52E-03 0,08892191 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 6,52E-03 0,08841378 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 6,52E-03 0,08791143 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,52E-03 0,08741476 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 6,52E-03 0,08692366 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 6,52E-03 0,08643806 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,52E-03 0,08595784 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 6,52E-03 0,08548294 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,52E-03 0,08501325 ! tyrosine catabolic process GO:0006572 7 5 0,000 6,52E-03 0,0845487 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,52E-03 0,0840892 ! proline biosynthetic process GO:0006561 6 5 0,000 6,52E-03 0,08363466 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,52E-03 0,08318501 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,52E-03 0,08274017 ! polyol catabolic process GO:0046174 7 5 0,000 6,52E-03 0,08230006 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,52E-03 0,08186461 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,52E-03 0,08143375 ! sister chromatid cohesion GO:0007062 10 5 0,000 6,52E-03 0,08100739 ! response to ATP GO:0033198 6 5 0,000 6,52E-03 0,08058548 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 6,52E-03 0,08016794 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 6,52E-03 0,0797547 ! neutrophil activation GO:0042119 6 5 0,000 6,52E-03 0,0793457 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,52E-03 0,07894088 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,52E-03 0,07854016 ! response to food GO:0032094 5 5 0,000 6,52E-03 0,07814349 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,52E-03 0,07775081 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 6,52E-03 0,07736206 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 6,52E-03 0,07697717 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,52E-03 0,0765961 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,52E-03 0,07621878 ! forebrain neuron development GO:0021884 7 5 0,000 6,52E-03 0,07584516 ! melanosome organization GO:0032438 7 5 0,000 6,52E-03 0,07547518 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,52E-03 0,0751088 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 6,52E-03 0,07474595 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 6,52E-03 0,0743866 ! mesodermal cell fate determination GO:0007500 7 5 0,000 6,52E-03 0,07403068 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,52E-03 0,07367815 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 6,52E-03 0,07332897 ! nucleoside salvage GO:0043174 7 5 0,000 6,52E-03 0,07298308 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 6,52E-03 0,07264043 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 6,52E-03 0,07230099 ! negative regulation of platelet activation GO:0010544 8 5 0,000 6,52E-03 0,07196471 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,52E-03 0,07163154 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,52E-03 0,07130144 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 6,52E-03 0,07097437 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 6,52E-03 0,07065028 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,52E-03 0,07032915 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 6,52E-03 0,07001091 ! depyrimidination GO:0045008 8 5 0,000 6,52E-03 0,06969555 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,52E-03 0,06938301 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,52E-03 0,06907327 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 6,52E-03 0,06876628 ! neuronal ion channel clustering GO:0045161 8 5 0,000 6,52E-03 0,068462 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,52E-03 0,0681604 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,52E-03 0,06786146 ! monocyte differentiation GO:0030224 7 5 0,000 6,52E-03 0,06756512 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 6,52E-03 0,06727136 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 6,52E-03 0,06698014 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,52E-03 0,06669143 ! response to UV-C GO:0010225 7 5 0,000 6,52E-03 0,0664052 ! protein targeting to vacuole GO:0006623 6 5 0,000 6,52E-03 0,06612142 ! activated T cell proliferation GO:0050798 7 5 0,000 6,52E-03 0,06584005 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 6,52E-03 0,06556107 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 6,52E-03 0,06528444 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,52E-03 0,06501013 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 6,52E-03 0,06473813 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 6,52E-03 0,06446838 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,52E-03 0,06420088 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 6,52E-03 0,06393559 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 6,52E-03 0,06367248 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 6,52E-03 0,06341152 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 6,52E-03 0,0631527 ! response to cadmium ion GO:0046686 8 5 0,000 6,52E-03 0,06289598 ! melanosome transport GO:0032402 8 5 0,000 6,52E-03 0,06264134 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,52E-03 0,06238876 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 6,52E-03 0,0621382 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,52E-03 0,06188965 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,52E-03 0,06164308 ! positive T cell selection GO:0043368 10 5 0,000 6,52E-03 0,06139846 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 6,52E-03 0,06115578 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,52E-03 0,06091501 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 6,52E-03 0,06067613 ! ribosomal subunit assembly GO:0042257 5 5 0,000 6,52E-03 0,06043911 ! base conversion or substitution editing GO:0016553 6 5 0,000 6,52E-03 0,06020394 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 6,52E-03 0,05997059 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 6,52E-03 0,05973904 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,52E-03 0,05950928 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 6,52E-03 0,05928127 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,52E-03 0,05905501 ! histone demethylation GO:0016577 10 5 0,000 6,52E-03 0,05883046 ! mitotic recombination GO:0006312 10 5 0,000 6,52E-03 0,05860762 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 6,52E-03 0,05838646 ! regulation of sterol transport GO:0032371 7 5 0,000 6,52E-03 0,05816696 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,52E-03 0,05794911 ! sympathetic nervous system development GO:0048485 13 5 0,000 6,52E-03 0,05773288 ! enteric nervous system development GO:0048484 9 5 0,000 6,52E-03 0,05751826 ! oxygen homeostasis GO:0032364 8 5 0,000 6,52E-03 0,05730523 ! establishment of planar polarity GO:0001736 7 5 0,000 6,52E-03 0,05709377 ! lymphocyte costimulation GO:0031294 12 5 0,000 6,52E-03 0,05688387 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 6,52E-03 0,0566755 ! transcription termination GO:0006353 8 5 0,000 6,52E-03 0,05646866 ! plasminogen activation GO:0031639 5 5 0,000 6,52E-03 0,05626332 ! B cell homeostasis GO:0001782 12 5 0,000 6,52E-03 0,05605946 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,52E-03 0,05585708 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,52E-03 0,05565616 ! regulation of hair follicle development GO:0051797 9 5 0,000 6,52E-03 0,05545667 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,52E-03 0,05525861 ! apical protein localization GO:0045176 8 5 0,000 6,52E-03 0,05506196 ! definitive hemopoiesis GO:0060216 5 5 0,000 6,52E-03 0,05486671 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 6,52E-03 0,05467283 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,52E-03 0,05448032 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 6,52E-03 0,05428916 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 6,52E-03 0,05409934 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,52E-03 0,05391084 ! regulation of centrosome duplication GO:0010824 6 5 0,000 6,52E-03 0,05372365 ! disaccharide metabolic process GO:0005984 9 5 0,000 6,52E-03 0,05353776 ! galactolipid metabolic process GO:0019374 8 5 0,000 6,52E-03 0,05335314 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,52E-03 0,0531698 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 6,52E-03 0,05298771 ! determination of adult lifespan GO:0008340 8 5 0,000 6,52E-03 0,05280687 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,52E-03 0,05262725 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 6,52E-03 0,05244885 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 6,52E-03 0,05227166 ! T cell activation during immune response GO:0002286 9 5 0,000 6,52E-03 0,05209566 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 6,52E-03 0,05192085 ! negative regulation of lipase activity GO:0060192 7 5 0,000 6,52E-03 0,0517472 ! establishment of apical/basal cell polarity GO:0035089 7 5 0,000 6,52E-03 0,05157471 ! neural plate development GO:0001840 7 5 0,000 6,52E-03 0,05140336 ! regulation of sensory perception GO:0051931 6 5 0,000 6,52E-03 0,05123315 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 6,52E-03 0,05106407 ! regulation of histone acetylation GO:0035065 7 5 0,000 6,52E-03 0,05089609 ! sensory cilium assembly GO:0035058 6 5 0,000 6,52E-03 0,05072922 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 6,52E-03 0,05056344 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 6,52E-03 0,05039874 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,52E-03 0,0502351 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 6,52E-03 0,05007253 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 6,52E-03 0,04991101 ! receptor biosynthetic process GO:0032800 6 5 0,000 6,52E-03 0,04975052 ! penetration of zona pellucida GO:0007341 9 5 0,000 6,52E-03 0,04959106 ! drug metabolic process GO:0017144 5 5 0,000 6,52E-03 0,04943263 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,52E-03 0,0492752 ! organ regeneration GO:0031100 7 5 0,000 6,52E-03 0,04911877 ! carnitine metabolic process GO:0009437 5 5 0,000 6,52E-03 0,04896333 GO:0006577|betaine metabolic process, ! regulation of cell adhesion GO:0030155 187 94 1,000 6,672E-03 0,04994655 ! tRNA transcription GO:0009304 11 6 0,000 7,819E-03 0,05834979 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 7,819E-03 0,05816687 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,819E-03 0,0579851 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 7,819E-03 0,05780446 ! regulation of helicase activity GO:0051095 11 6 0,000 7,819E-03 0,05762494 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 7,819E-03 0,05744654 ! sleep GO:0030431 13 6 0,000 7,819E-03 0,05726924 ! positive regulation of axon extension GO:0045773 10 6 0,000 7,819E-03 0,05709302 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 7,819E-03 0,05691789 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,819E-03 0,05674383 ! forebrain regionalization GO:0021871 7 6 0,000 7,819E-03 0,05657083 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,819E-03 0,05639888 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,819E-03 0,05622798 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,819E-03 0,0560581 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,819E-03 0,05588925 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 7,819E-03 0,05572142 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 7,819E-03 0,05555459 ! neuron adhesion GO:0007158 9 6 0,000 7,819E-03 0,05538875 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,819E-03 0,05522391 ! signal peptide processing GO:0006465 8 6 0,000 7,819E-03 0,05506004 ! embryonic camera-type eye development GO:0031076 11 6 0,000 7,819E-03 0,05489714 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,819E-03 0,0547352 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 7,819E-03 0,05457421 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 7,819E-03 0,05441417 ! fibril organization GO:0043206 13 6 0,000 7,819E-03 0,05425507 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 7,819E-03 0,05409689 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 7,819E-03 0,05393963 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 7,819E-03 0,05378328 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 7,819E-03 0,05362784 ! protein refolding GO:0042026 13 6 0,000 7,819E-03 0,05347329 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 7,819E-03 0,05331963 ! rhythmic behavior GO:0007622 14 6 0,000 7,819E-03 0,05316685 ! glial cell fate commitment GO:0021781 17 6 0,000 7,819E-03 0,05301495 ! erythrocyte maturation GO:0043249 7 6 0,000 7,819E-03 0,05286391 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 7,819E-03 0,05271373 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,819E-03 0,0525644 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,819E-03 0,05241591 ! regulation of odontogenesis GO:0042481 8 6 0,000 7,819E-03 0,05226826 ! mechanosensory behavior GO:0007638 8 6 0,000 7,819E-03 0,05212144 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 7,819E-03 0,05197544 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,819E-03 0,05183026 ! response to interferon-gamma GO:0034341 12 6 0,000 7,819E-03 0,05168588 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,819E-03 0,05154231 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 7,819E-03 0,05139954 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 7,819E-03 0,05125755 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 7,819E-03 0,05111634 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 7,819E-03 0,05097591 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 7,819E-03 0,05083625 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 7,819E-03 0,05069736 ! cGMP-mediated signaling GO:0019934 11 6 0,000 7,819E-03 0,05055922 ! activation of MAPKKK activity GO:0000185 11 6 0,000 7,819E-03 0,05042183 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 7,819E-03 0,05028518 ! protein lipoylation GO:0009249 10 6 0,000 7,819E-03 0,05014928 ! pigment granule organization GO:0048753 11 6 0,000 7,819E-03 0,0500141 ! drug transport GO:0015893 6 6 0,000 7,819E-03 0,04987966 ! transepithelial chloride transport GO:0030321 10 6 0,000 7,819E-03 0,04974593 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 7,819E-03 0,04961292 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 7,819E-03 0,04948062 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,819E-03 0,04934902 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 7,819E-03 0,04921812 ! glutamate catabolic process GO:0006538 11 6 0,000 7,819E-03 0,04908792 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,819E-03 0,0489584 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 7,819E-03 0,04882956 ! adenohypophysis development GO:0021984 10 6 0,000 7,819E-03 0,0487014 ! response to pH GO:0009268 10 6 0,000 7,819E-03 0,04857391 ! hyperosmotic response GO:0006972 9 6 0,000 7,819E-03 0,04844708 ! microtubule nucleation GO:0007020 10 6 0,000 7,819E-03 0,04832092 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 7,819E-03 0,04819541 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 7,819E-03 0,04807055 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 7,819E-03 0,04794634 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,819E-03 0,04782276 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 7,819E-03 0,04769983 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 7,819E-03 0,04757752 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,819E-03 0,04745584 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 7,819E-03 0,04733478 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,819E-03 0,04721433 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,819E-03 0,0470945 ! purine salvage GO:0043101 9 6 0,000 7,819E-03 0,04697527 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,819E-03 0,04685665 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 7,819E-03 0,04673862 ! nucleoside transport GO:0015858 7 6 0,000 7,819E-03 0,04662119 ! organic alcohol transport GO:0015850 9 6 0,000 7,819E-03 0,04650434 ! T cell mediated immunity GO:0002456 12 6 0,000 7,819E-03 0,04638808 ! folic acid transport GO:0015884 11 6 0,000 7,819E-03 0,0462724 ! male sex determination GO:0030238 11 6 0,000 7,819E-03 0,04615729 ! carnitine transport GO:0015879 8 6 0,000 7,819E-03 0,04604276 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,819E-03 0,04592879 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,819E-03 0,04581539 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 7,819E-03 0,04570254 ! positive regulation of exocytosis GO:0045921 9 6 0,000 7,819E-03 0,04559025 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,819E-03 0,04547851 ! parturition GO:0007567 13 6 0,000 7,819E-03 0,04536732 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 7,819E-03 0,04525666 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,819E-03 0,04514655 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 7,819E-03 0,04503697 ! regulation of centrosome cycle GO:0046605 8 6 0,000 7,819E-03 0,04492792 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,819E-03 0,0448194 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,819E-03 0,0447114 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 7,819E-03 0,04460392 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 7,819E-03 0,04449696 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,819E-03 0,04439051 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 7,819E-03 0,04428456 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 7,819E-03 0,04417912 ! neural nucleus development GO:0048857 12 6 0,000 7,819E-03 0,04407419 ! forebrain morphogenesis GO:0048853 14 6 0,000 7,819E-03 0,04396974 ! hyaluronan metabolic process GO:0030212 7 6 0,000 7,819E-03 0,0438658 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,819E-03 0,04376234 ! interaction with symbiont GO:0051702 9 6 0,000 7,819E-03 0,04365937 ! regulation of dendrite development GO:0050773 13 6 0,000 7,819E-03 0,04355688 ! anterograde axon cargo transport GO:0008089 9 6 0,000 7,819E-03 0,04345488 ! positive regulation of organ growth GO:0046622 7 6 0,000 7,819E-03 0,04335335 ! eating behavior GO:0042755 6 6 0,000 7,819E-03 0,04325229 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 7,819E-03 0,0431517 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 7,819E-03 0,04305158 ! response to copper ion GO:0046688 9 6 0,000 7,819E-03 0,04295193 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 7,819E-03 0,04285273 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,819E-03 0,04275399 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,819E-03 0,04265571 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,819E-03 0,04255787 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 7,819E-03 0,04246049 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 7,819E-03 0,04236354 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,819E-03 0,04226704 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,819E-03 0,04217098 ! hair follicle maturation GO:0048820 8 6 0,000 7,819E-03 0,04207536 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 7,819E-03 0,04198016 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,819E-03 0,0418854 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 7,819E-03 0,04179106 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,819E-03 0,04169715 ! rhombomere development GO:0021546 6 6 0,000 7,819E-03 0,04160366 ! G2 phase GO:0051319 15 6 0,000 7,819E-03 0,04151059 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 7,819E-03 0,04141793 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 7,819E-03 0,04132568 ! muscle cell proliferation GO:0033002 9 6 0,000 7,819E-03 0,04123385 ! membrane to membrane docking GO:0022614 12 6 0,000 7,819E-03 0,04114242 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 7,819E-03 0,0410514 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 7,819E-03 0,04096078 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 7,819E-03 0,04087056 ! receptor internalization GO:0031623 9 6 0,000 7,819E-03 0,04078073 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,819E-03 0,0406913 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 7,819E-03 0,04060226 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,819E-03 0,04051361 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 7,819E-03 0,04042534 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 7,819E-03 0,04033746 ! peptidyl-histidine modification GO:0018202 10 6 0,000 7,819E-03 0,04024996 ! axonal fasciculation GO:0007413 10 6 0,000 7,819E-03 0,04016284 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 7,819E-03 0,0400761 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 7,819E-03 0,03998972 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 7,819E-03 0,03990373 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 7,819E-03 0,0398181 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,819E-03 0,03973283 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 7,819E-03 0,03964793 ! progesterone metabolic process GO:0042448 8 6 0,000 7,819E-03 0,0395634 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,819E-03 0,03947922 ! glycolipid catabolic process GO:0019377 14 6 0,000 7,819E-03 0,0393954 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 7,819E-03 0,03931193 ! negative regulation of axon extension GO:0030517 13 6 0,000 7,819E-03 0,03922882 ! removal of superoxide radicals GO:0019430 10 6 0,000 7,819E-03 0,03914606 ! triglyceride catabolic process GO:0019433 8 6 0,000 7,819E-03 0,03906365 ! protein modification by small protein removal GO:0070646 10 6 0,000 7,819E-03 0,03898158 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 7,819E-03 0,03889986 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 7,819E-03 0,03881848 ! glial cell migration GO:0008347 11 6 0,000 7,819E-03 0,03873744 ! blastocyst growth GO:0001832 17 6 0,000 7,819E-03 0,03865673 ! pigment granule transport GO:0051904 12 6 0,000 7,819E-03 0,03857637 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 7,819E-03 0,03849633 ! cerebellar cortex formation GO:0021697 9 6 0,000 7,819E-03 0,03841663 ! catecholamine transport GO:0051937 7 6 0,000 7,819E-03 0,03833726 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 7,819E-03 0,03825821 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 7,819E-03 0,03817949 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,819E-03 0,03810109 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 7,819E-03 0,03802302 ! spindle assembly GO:0051225 6 6 0,000 7,819E-03 0,03794526 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 7,819E-03 0,03786782 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 7,819E-03 0,0377907 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 7,819E-03 0,03771389 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,819E-03 0,03763739 ! NAD biosynthetic process GO:0009435 9 6 0,000 7,819E-03 0,0375612 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,819E-03 0,03748532 ! cellular anion homeostasis GO:0030002 9 6 0,000 7,819E-03 0,03740974 GO:0055081|anion homeostasis, ! behavioral response to cocaine GO:0048148 13 7 0,000 9,117E-03 0,04352953 ! autophagic vacuole formation GO:0000045 12 7 0,000 9,117E-03 0,04344212 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,117E-03 0,04335506 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 9,117E-03 0,04326835 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 9,117E-03 0,04318199 ! prostate gland development GO:0030850 11 7 0,000 9,117E-03 0,04309597 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 9,117E-03 0,04301029 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 9,117E-03 0,04292495 ! synaptonemal complex assembly GO:0007130 11 7 0,000 9,117E-03 0,04283995 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 9,117E-03 0,04275529 ! male meiosis GO:0007140 10 7 0,000 9,117E-03 0,04267096 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,117E-03 0,04258696 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 9,117E-03 0,04250329 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 9,117E-03 0,04241995 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 9,117E-03 0,04233694 ! oligopeptide transport GO:0006857 11 7 0,000 9,117E-03 0,04225425 ! protein amino acid sulfation GO:0006477 9 7 0,000 9,117E-03 0,04217188 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 9,117E-03 0,04208984 ! establishment of tissue polarity GO:0007164 10 7 0,000 9,117E-03 0,04200811 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 9,117E-03 0,0419267 ! RNA methylation GO:0001510 11 7 0,000 9,117E-03 0,0418456 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 9,117E-03 0,04176482 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 9,117E-03 0,04168435 ! pericardium development GO:0060039 9 7 0,000 9,117E-03 0,04160419 ! macrophage chemotaxis GO:0048246 10 7 0,000 9,117E-03 0,04152433 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 9,117E-03 0,04144478 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,117E-03 0,04136554 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,117E-03 0,0412866 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 9,117E-03 0,04120795 ! cerebral cortex cell migration GO:0021795 11 7 0,000 9,117E-03 0,04112961 ! opsonization GO:0008228 9 7 0,000 9,117E-03 0,04105157 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 9,117E-03 0,04097382 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,117E-03 0,04089636 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 9,117E-03 0,0408192 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 9,117E-03 0,04074233 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 9,117E-03 0,04066574 ! chemosensory behavior GO:0007635 9 7 0,000 9,117E-03 0,04058945 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 9,117E-03 0,04051344 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 9,117E-03 0,04043771 ! leukocyte degranulation GO:0043299 11 7 0,000 9,117E-03 0,04036227 ! positive regulation of glycolysis GO:0045821 13 7 0,000 9,117E-03 0,04028711 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 9,117E-03 0,04021222 ! positive regulation of heart rate GO:0010460 11 7 0,000 9,117E-03 0,04013762 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,117E-03 0,04006329 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 9,117E-03 0,03998924 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 9,117E-03 0,03991545 ! spinal cord patterning GO:0021511 9 7 0,000 9,117E-03 0,03984195 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 9,117E-03 0,03976871 ! thymic T cell selection GO:0045061 15 7 0,000 9,117E-03 0,03969574 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 9,117E-03 0,03962303 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 9,117E-03 0,0395506 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 9,117E-03 0,03947842 ! ovulation GO:0030728 8 7 0,000 9,117E-03 0,03940651 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 9,117E-03 0,03933487 ! histidine metabolic process GO:0006547 7 7 0,000 9,117E-03 0,03926348 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 9,117E-03 0,03919235 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 9,117E-03 0,03912148 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 9,117E-03 0,03905086 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 9,117E-03 0,0389805 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 9,117E-03 0,03891039 ! thyroid hormone generation GO:0006590 11 7 0,000 9,117E-03 0,03884053 ! endosome organization GO:0007032 10 7 0,000 9,117E-03 0,03877093 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 9,117E-03 0,03870157 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 9,117E-03 0,03863246 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 9,117E-03 0,03856359 ! urea metabolic process GO:0019627 9 7 0,000 9,117E-03 0,03849498 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 9,117E-03 0,0384266 ! vesicle fusion GO:0006906 15 7 0,000 9,117E-03 0,03835847 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 9,117E-03 0,03829058 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 9,117E-03 0,03822293 ! intracellular pH reduction GO:0051452 11 7 0,000 9,117E-03 0,03815551 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 9,117E-03 0,03808834 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 9,117E-03 0,0380214 ! organ growth GO:0035265 13 7 0,000 9,117E-03 0,0379547 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 9,117E-03 0,03788822 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,117E-03 0,03782199 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 9,117E-03 0,03775598 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 9,117E-03 0,0376902 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 9,117E-03 0,03762465 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 9,117E-03 0,03755933 ! rRNA modification GO:0000154 12 7 0,000 9,117E-03 0,03749424 ! negative regulation of translational initiation GO:0045947 9 7 0,000 9,117E-03 0,03742937 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 9,117E-03 0,03736473 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 9,117E-03 0,0373003 ! protein heterooligomerization GO:0051291 10 7 0,000 9,117E-03 0,0372361 ! response to UV-B GO:0010224 11 7 0,000 9,117E-03 0,03717212 ! astrocyte development GO:0014002 15 7 0,000 9,117E-03 0,03710836 ! intermediate filament organization GO:0045109 12 7 0,000 9,117E-03 0,03704482 ! cardiac muscle cell development GO:0055013 9 7 0,000 9,117E-03 0,0369815 ! fibrinolysis GO:0042730 9 7 0,000 9,117E-03 0,03691839 ! peptidyl-arginine modification GO:0018195 9 7 0,000 9,117E-03 0,0368555 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 9,117E-03 0,03679282 ! blastoderm segmentation GO:0007350 11 7 0,000 9,117E-03 0,03673035 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,117E-03 0,0366681 ! B cell lineage commitment GO:0002326 17 7 0,000 9,117E-03 0,03660605 ! DNA topological change GO:0006265 10 7 0,000 9,117E-03 0,03654422 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 9,117E-03 0,03648259 ! melanosome localization GO:0032400 10 7 0,000 9,117E-03 0,03642117 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 9,117E-03 0,03635996 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 9,117E-03 0,03629895 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 9,117E-03 0,03623815 ! mast cell activation GO:0045576 10 7 0,000 9,117E-03 0,03617755 ! multicellular organismal aging GO:0010259 11 7 0,000 9,117E-03 0,03611716 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 9,117E-03 0,03605696 ! gas homeostasis GO:0033483 12 7 0,000 9,117E-03 0,03599697 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 9,117E-03 0,03593717 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 9,117E-03 0,03587757 ! Schwann cell development GO:0014044 16 7 0,000 9,117E-03 0,03581817 ! dendrite morphogenesis GO:0048813 12 7 0,000 9,117E-03 0,03575897 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 9,117E-03 0,03569996 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 9,117E-03 0,03564115 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 9,117E-03 0,03558253 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 9,117E-03 0,0355241 ! neural tube patterning GO:0021532 8 7 0,000 9,117E-03 0,03546586 ! histone ubiquitination GO:0016574 10 7 0,000 9,117E-03 0,03540782 ! regulation of meiosis GO:0040020 12 7 0,000 9,117E-03 0,03534996 GO:0051445|regulation of meiotic cell cycle, ! eye photoreceptor cell differentiation GO:0001754 14 7 0,000 9,117E-03 0,03529229 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 12 7 0,000 9,117E-03 0,03523481 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 9,117E-03 0,03517752 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 9,117E-03 0,03512042 ! regulation of lipid transport GO:0032368 13 7 0,000 9,117E-03 0,03506349 ! regulation of cell division GO:0051302 9 7 0,000 9,117E-03 0,03500676 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 9,117E-03 0,0349502 ! neutrophil homeostasis GO:0001780 8 7 0,000 9,117E-03 0,03489383 ! regulation of macrophage activation GO:0043030 12 7 0,000 9,117E-03 0,03483764 ! negative regulation of nuclear division GO:0051784 18 7 0,000 9,117E-03 0,03478163 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 9,117E-03 0,0347258 ! diuresis GO:0030146 11 7 0,000 9,117E-03 0,03467015 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 9,117E-03 0,03461468 ! positive regulation of epidermis development GO:0045684 11 7 0,000 9,117E-03 0,03455939 ! thiamin metabolic process GO:0006772 8 7 0,000 9,117E-03 0,03450427 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 9,117E-03 0,03444933 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 9,117E-03 0,03439456 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 9,117E-03 0,03433996 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 9,117E-03 0,03428554 ! dopamine biosynthetic process GO:0042416 15 7 0,000 9,117E-03 0,03423129 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 9,117E-03 0,03417721 ! lymph node development GO:0048535 9 7 0,000 9,117E-03 0,03412331 ! anterior/posterior axis specification GO:0009948 11 7 0,000 9,117E-03 0,03406957 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 9,117E-03 0,034016 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 9,117E-03 0,0339626 ! positive regulation of glucose import GO:0046326 7 7 0,000 9,117E-03 0,03390937 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 9,117E-03 0,0338563 ! ATP catabolic process GO:0006200 10 7 0,000 9,117E-03 0,0338034 ! establishment of pigment granule localization GO:0051905 13 7 0,000 9,117E-03 0,03375066 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 9,117E-03 0,03369809 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 9,117E-03 0,03364569 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 9,117E-03 0,03359344 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 9,117E-03 0,03354136 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 9,117E-03 0,03348944 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,117E-03 0,03343768 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 9,117E-03 0,03338607 ! muscle adaptation GO:0043500 12 7 0,000 9,117E-03 0,03333463 ! amino sugar catabolic process GO:0046348 9 7 0,000 9,117E-03 0,03328335 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 9,117E-03 0,03323222 ! retina homeostasis GO:0001895 9 7 0,000 9,117E-03 0,03318125 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,117E-03 0,03313044 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 9,117E-03 0,03307978 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 9,117E-03 0,03302928 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 9,117E-03 0,03297893 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,117E-03 0,03292873 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01041266 0,03755205 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01041266 0,03749507 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01041266 0,03743826 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01041266 0,03738162 ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01041266 0,03732515 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01041266 0,03726885 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01041266 0,03721272 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01041266 0,03715676 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01041266 0,03710097 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01041266 0,03704535 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01041266 0,03698989 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01041266 0,0369346 ! N-glycan processing GO:0006491 12 8 0,000 0,01041266 0,03687948 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01041266 0,03682451 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01041266 0,03676972 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01041266 0,03671508 ! mRNA stabilization GO:0048255 16 8 0,000 0,01041266 0,03666061 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01041266 0,03660629 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01041266 0,03655214 ! lipoprotein transport GO:0042953 14 8 0,000 0,01041266 0,03649815 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01041266 0,03644432 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01041266 0,03639065 ! keratinocyte proliferation GO:0043616 15 8 0,000 0,01041266 0,03633713 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01041266 0,03628377 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01041266 0,03623057 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01041266 0,03617752 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01041266 0,03612463 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01041266 0,0360719 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01041266 0,03601931 ! reflex GO:0060004 16 8 0,000 0,01041266 0,03596688 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01041266 0,03591461 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01041266 0,03586248 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01041266 0,03581051 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01041266 0,03575868 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01041266 0,03570701 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01041266 0,03565548 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01041266 0,0356041 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01041266 0,03555288 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01041266 0,03550179 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01041266 0,03545086 ! adrenal gland development GO:0030325 18 8 0,000 0,01041266 0,03540007 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01041266 0,03534943 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01041266 0,03529893 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01041266 0,03524857 ! proline metabolic process GO:0006560 9 8 0,000 0,01041266 0,03519836 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01041266 0,03514829 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01041266 0,03509836 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01041266 0,03504858 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01041266 0,03499894 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01041266 0,03494943 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01041266 0,03490007 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01041266 0,03485084 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01041266 0,03480176 ! galactose metabolic process GO:0006012 14 8 0,000 0,01041266 0,03475281 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01041266 0,034704 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01041266 0,03465533 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01041266 0,03460679 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01041266 0,03455839 ! ruffle organization GO:0031529 12 8 0,000 0,01041266 0,03451012 ! osteoblast development GO:0002076 14 8 0,000 0,01041266 0,03446199 ! macroautophagy GO:0016236 14 8 0,000 0,01041266 0,034414 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01041266 0,03436613 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01041266 0,0343184 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01041266 0,0342708 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01041266 0,03422334 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01041266 0,034176 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01041266 0,0341288 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01041266 0,03408172 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01041266 0,03403478 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01041266 0,03398796 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01041266 0,03394128 ! pigment granule localization GO:0051875 14 8 0,000 0,01041266 0,03389472 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01041266 0,03384829 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01041266 0,03380198 ! response to tropane GO:0014073 14 8 0,000 0,01041266 0,0337558 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01041266 0,03370975 ! embryonic axis specification GO:0000578 12 8 0,000 0,01041266 0,03366383 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01041266 0,03361803 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01041266 0,03357235 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01041266 0,0335268 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01041266 0,03348137 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01041266 0,03343606 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01041266 0,03339088 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01041266 0,03334581 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01041266 0,03330087 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01041266 0,03325605 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01041266 0,03321136 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01041266 0,03316678 ! icosanoid secretion GO:0032309 12 8 0,000 0,01041266 0,03312232 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01041266 0,03307798 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01041266 0,03303375 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01041266 0,03298965 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01041266 0,03294566 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01041266 0,0329018 ! S phase GO:0051320 8 8 0,000 0,01041266 0,03285804 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01041266 0,03281441 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01041266 0,03277089 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01041266 0,03272748 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01041266 0,03268419 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01041266 0,03264102 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01041266 0,03259795 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01041266 0,032555 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01041266 0,03251217 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01041266 0,03246945 ! hormone catabolic process GO:0042447 13 8 0,000 0,01041266 0,03242684 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01041266 0,03238434 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01041266 0,03234195 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01041266 0,03229967 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01041266 0,0322575 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01041266 0,03221545 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01041266 0,0321735 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01041266 0,03213166 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01041266 0,03208993 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01041266 0,03204831 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01041266 0,0320068 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01041266 0,03196539 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01041266 0,03192409 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01041266 0,0318829 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01041266 0,03184182 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01041266 0,03180083 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01041266 0,03175996 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01041266 0,03171919 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01041266 0,03167852 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01041266 0,03163796 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01170689 0,03552488 ! regulation of developmental growth GO:0048638 14 9 0,000 0,01170689 0,03547951 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,01170689 0,03543425 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01170689 0,03538911 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,01170689 0,03534409 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,01170689 0,03529918 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,01170689 0,03525438 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,01170689 0,0352097 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,01170689 0,03516513 ! cell volume homeostasis GO:0006884 14 9 0,000 0,01170689 0,03512067 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,01170689 0,03507633 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,01170689 0,0350321 ! UTP metabolic process GO:0046051 10 9 0,000 0,01170689 0,03498798 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,01170689 0,03494397 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,01170689 0,03490007 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,01170689 0,03485628 ! protein complex disassembly GO:0043241 17 9 0,000 0,01170689 0,0348126 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01170689 0,03476903 ! estrogen metabolic process GO:0008210 16 9 0,000 0,01170689 0,03472557 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01170689 0,03468221 ! photoreceptor cell development GO:0042461 17 9 0,000 0,01170689 0,03463897 GO:0046530|photoreceptor cell differentiation, ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,01170689 0,03459583 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,01170689 0,0345528 ! microtubule bundle formation GO:0001578 14 9 0,000 0,01170689 0,03450988 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,01170689 0,03446706 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,01170689 0,03442435 ! lung alveolus development GO:0048286 18 9 0,000 0,01170689 0,03438175 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01170689 0,03433925 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,01170689 0,03429686 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,01170689 0,03425457 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01170689 0,03421238 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01170689 0,0341703 ! endoderm development GO:0007492 12 9 0,000 0,01170689 0,03412832 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01170689 0,03408645 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01170689 0,03404467 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,01170689 0,034003 ! astrocyte differentiation GO:0048708 17 9 0,000 0,01170689 0,03396143 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,01170689 0,03391997 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,01170689 0,0338786 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01170689 0,03383734 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,01170689 0,03379617 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,01170689 0,03375511 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,01170689 0,03371414 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,01170689 0,03367328 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,01170689 0,03363251 ! macrophage activation GO:0042116 14 9 0,000 0,01170689 0,03359184 ! multicellular organism growth GO:0035264 16 9 0,000 0,01170689 0,03355127 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,01170689 0,0335108 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01170689 0,03347043 ! neuron apoptosis GO:0051402 12 9 0,000 0,01170689 0,03343015 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,01170689 0,03338997 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,01170689 0,03334988 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01170689 0,0333099 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,01170689 0,03327 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01170689 0,03323021 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,01170689 0,03319051 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,01170689 0,0331509 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,01170689 0,03311139 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,01170689 0,03307197 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,01170689 0,03303264 ! oligodendrocyte development GO:0014003 13 9 0,000 0,01170689 0,03299341 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,01170689 0,03295427 ! segment specification GO:0007379 11 9 0,000 0,01170689 0,03291523 ! cellular extravasation GO:0045123 12 9 0,000 0,01170689 0,03287628 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01170689 0,03283742 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,01170689 0,03279865 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01170689 0,03275997 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01170689 0,03272138 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,01170689 0,03268289 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,01170689 0,03264448 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,01170689 0,03260617 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,01170689 0,03256794 ! response to amine stimulus GO:0014075 13 9 0,000 0,01170689 0,03252981 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,01170689 0,03249176 ! erythrocyte development GO:0048821 13 9 0,000 0,01170689 0,0324538 ! renal water homeostasis GO:0003091 13 9 0,000 0,01170689 0,03241593 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,01170689 0,03237815 ! nucleosome disassembly GO:0006337 13 9 0,000 0,01170689 0,03234046 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,01170689 0,03230285 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,01170689 0,03226534 ! induction of an organ GO:0001759 13 9 0,000 0,01170689 0,0322279 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,01170689 0,03219056 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,01170689 0,0321533 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,01170689 0,03211613 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,01170689 0,03207905 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01170689 0,03204205 ! sterol catabolic process GO:0016127 11 9 0,000 0,01170689 0,03200513 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,01170689 0,0319683 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01170689 0,03193156 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,01170689 0,0318949 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,01170689 0,03185832 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01170689 0,03182183 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,01170689 0,03178542 ! prophase GO:0051324 12 9 0,000 0,01170689 0,03174909 ! neuroblast proliferation GO:0007405 19 9 0,000 0,01170689 0,03171285 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 0,000 0,01170689 0,03167669 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,01170689 0,03164061 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,01170689 0,03160461 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,01170689 0,0315687 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,01170689 0,03153286 ! acid secretion GO:0046717 14 9 0,000 0,01170689 0,03149711 ! purine base metabolic process GO:0006144 18 9 0,000 0,01170689 0,03146144 ! detection of calcium ion GO:0005513 13 9 0,000 0,01170689 0,03142585 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,01170689 0,03139034 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,01170689 0,03135491 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01170689 0,03131956 ! natural killer cell mediated immunity GO:0002228 14 9 0,000 0,01170689 0,03128429 GO:0042267|natural killer cell mediated cytotoxicity, ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,01170689 0,0312491 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01170689 0,03121399 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01170689 0,03117896 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,01170689 0,03114401 ! prepulse inhibition GO:0060134 14 9 0,000 0,01170689 0,03110913 ! sequestering of metal ion GO:0051238 12 9 0,000 0,01170689 0,03107433 ! lamellipodium assembly GO:0030032 12 9 0,000 0,01170689 0,03103961 ! regulation of embryonic development GO:0045995 17 9 0,000 0,01170689 0,03100497 ! mitochondrion localization GO:0051646 15 9 0,000 0,01170689 0,03097041 ! localization within membrane GO:0051668 15 9 0,000 0,01170689 0,03093592 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01299949 0,03431346 ! axon extension GO:0048675 13 10 0,000 0,01299949 0,03427533 ! neuron fate specification GO:0048665 12 10 0,000 0,01299949 0,03423729 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01299949 0,03419933 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01299949 0,03416146 ! associative learning GO:0008306 19 10 0,000 0,01299949 0,03412367 ! positive regulation of B cell proliferation GO:0030890 14 10 0,000 0,01299949 0,03408596 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01299949 0,03404834 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01299949 0,0340108 ! CTP metabolic process GO:0046036 11 10 0,000 0,01299949 0,03397334 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01299949 0,03393597 ! GTP metabolic process GO:0046039 11 10 0,000 0,01299949 0,03389868 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01299949 0,03386147 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01299949 0,03382434 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01299949 0,03378729 ! social behavior GO:0035176 15 10 0,000 0,01299949 0,03375032 ! sulfate transport GO:0008272 12 10 0,000 0,01299949 0,03371344 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01299949 0,03367663 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01299949 0,03363991 ! artery development GO:0060840 20 10 0,000 0,01299949 0,03360326 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01299949 0,0335667 ! response to pain GO:0048265 20 10 0,000 0,01299949 0,03353021 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01299949 0,03349381 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01299949 0,03345748 ! phospholipid efflux GO:0033700 17 10 0,000 0,01299949 0,03342123 ! hippocampus development GO:0021766 19 10 0,000 0,01299949 0,03338506 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01299949 0,03334897 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01299949 0,03331296 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01299949 0,03327702 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01299949 0,03324116 ! pathogenesis GO:0009405 13 10 0,000 0,01299949 0,03320538 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01299949 0,03316967 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01299949 0,03313405 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01299949 0,03309849 ! protein targeting to ER GO:0045047 21 10 0,000 0,01299949 0,03306302 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01299949 0,03302762 ! arginine catabolic process GO:0006527 12 10 0,000 0,01299949 0,0329923 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01299949 0,03295705 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01299949 0,03292187 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01299949 0,03288678 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01299949 0,03285175 ! B cell proliferation GO:0042100 16 10 0,000 0,01299949 0,0328168 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01299949 0,03278193 ! mannose metabolic process GO:0006013 11 10 0,000 0,01299949 0,03274713 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01299949 0,0327124 ! forebrain cell migration GO:0021885 17 10 0,000 0,01299949 0,03267775 ! lipid digestion GO:0044241 15 10 0,000 0,01299949 0,03264317 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01299949 0,03260866 ! receptor clustering GO:0043113 18 10 0,000 0,01299949 0,03257423 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01299949 0,03253987 ! UV protection GO:0009650 14 10 0,000 0,01299949 0,03250558 ! entry into host cell GO:0030260 21 10 0,000 0,01299949 0,03247136 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01299949 0,03243722 ! behavioral fear response GO:0001662 19 10 0,000 0,01299949 0,03240315 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01299949 0,03236915 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01299949 0,03233522 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01299949 0,03230136 ! protein homotetramerization GO:0051289 20 10 0,000 0,01299949 0,03226757 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01299949 0,03223385 ! response to dsRNA GO:0043331 19 10 0,000 0,01299949 0,03220021 ! DNA ligation GO:0006266 16 10 0,000 0,01299949 0,03216663 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01299949 0,03213312 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01299949 0,03209968 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01299949 0,03206632 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01299949 0,03203302 ! postreplication repair GO:0006301 16 10 0,000 0,01299949 0,03199979 ! fucose catabolic process GO:0019317 17 10 0,000 0,01299949 0,03196663 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01299949 0,03193354 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01299949 0,03190051 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01299949 0,03186756 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01299949 0,03183467 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01299949 0,03180185 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01299949 0,0317691 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01299949 0,03173642 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01299949 0,0317038 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01299949 0,03167125 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01299949 0,03163877 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01299949 0,03160635 ! oocyte differentiation GO:0009994 14 10 0,000 0,01299949 0,031574 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01299949 0,03154171 ! spleen development GO:0048536 17 10 0,000 0,01299949 0,0315095 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01299949 0,03147734 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01299949 0,03144526 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01299949 0,03141323 ! blastocyst formation GO:0001825 14 10 0,000 0,01299949 0,03138128 ! embryonic gut development GO:0048566 13 10 0,000 0,01299949 0,03134939 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01299949 0,03131756 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01299949 0,0312858 ! activation of innate immune response GO:0002218 10 10 0,000 0,01299949 0,0312541 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01299949 0,03122247 ! insulin secretion GO:0030073 18 10 0,000 0,01299949 0,0311909 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01299949 0,03115939 ! response to nicotine GO:0035094 18 10 0,000 0,01299949 0,03112795 ! establishment of cell polarity GO:0030010 12 10 0,000 0,01299949 0,03109657 ! nucleus localization GO:0051647 16 10 0,000 0,01299949 0,03106525 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01299949 0,031034 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01429047 0,03408169 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01429047 0,03404747 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01429047 0,03401332 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01429047 0,03397924 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01429047 0,03394523 ! virus-host interaction GO:0019048 20 11 0,000 0,01429047 0,03391128 ! thyroid gland development GO:0030878 20 11 0,000 0,01429047 0,0338774 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01429047 0,03384359 GO:0006740|NADPH regeneration, ! non-recombinational repair GO:0000726 19 11 0,000 0,01429047 0,03380985 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01429047 0,03377618 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01429047 0,03374257 ! Golgi vesicle budding GO:0048194 18 11 0,000 0,01429047 0,03370903 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01429047 0,03367555 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01429047 0,03364214 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01429047 0,0336088 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01429047 0,03357553 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01429047 0,03354232 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01429047 0,03350917 ! bone resorption GO:0045453 16 11 0,000 0,01429047 0,03347609 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01429047 0,03344308 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01429047 0,03341013 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01429047 0,03337725 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01429047 0,03334443 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01429047 0,03331167 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01429047 0,03327898 ! syncytium formation GO:0006949 15 11 0,000 0,01429047 0,03324635 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01429047 0,03321379 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01429047 0,03318129 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01429047 0,03314886 ! Golgi organization GO:0007030 19 11 0,000 0,01429047 0,03311649 ! response to X-ray GO:0010165 19 11 0,000 0,01429047 0,03308418 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01429047 0,03305193 ! adult heart development GO:0007512 12 11 0,000 0,01429047 0,03301975 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01429047 0,03298763 ! epithelial cell development GO:0002064 16 11 0,000 0,01429047 0,03295557 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01429047 0,03292357 ! temperature homeostasis GO:0001659 16 11 0,000 0,01429047 0,03289164 ! L-glutamate transport GO:0015813 15 11 0,000 0,01429047 0,03285977 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01429047 0,03282796 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01429047 0,03279621 ! motor axon guidance GO:0008045 17 11 0,000 0,01429047 0,03276452 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01429047 0,0327329 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01429047 0,03270133 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01429047 0,03266983 ! stem cell development GO:0048864 30 11 0,000 0,01429047 0,03263838 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01429047 0,032607 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01429047 0,03257568 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01429047 0,03254442 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01429047 0,03251321 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01429047 0,03248207 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01429047 0,03245099 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01429047 0,03241996 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01429047 0,032389 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01429047 0,03235809 ! cranial nerve development GO:0021545 14 11 0,000 0,01429047 0,03232725 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01429047 0,03229646 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01429047 0,03226573 ! salivary gland development GO:0007431 24 11 0,000 0,01429047 0,03223506 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01429047 0,03220445 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01429047 0,03217389 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01429047 0,03214339 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01429047 0,03211296 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01429047 0,03208257 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01429047 0,03205225 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01429047 0,03202198 ! cholesterol efflux GO:0033344 20 11 0,000 0,01429047 0,03199178 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01429047 0,03196162 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01429047 0,03193153 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01429047 0,03190149 ! leukocyte mediated cytotoxicity GO:0001909 18 11 0,000 0,01429047 0,03187151 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01429047 0,03184158 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01429047 0,03181171 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01429047 0,03178189 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01429047 0,03175214 ! defense response to fungus GO:0050832 13 11 0,000 0,01429047 0,03172243 ! lysogeny GO:0030069 20 11 0,000 0,01429047 0,03169279 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01429047 0,03166319 ! acrosome reaction GO:0007340 14 11 0,000 0,01429047 0,03163366 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01429047 0,03160418 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01429047 0,03157475 ! rRNA transcription GO:0009303 19 12 0,000 0,01557982 0,03439155 ! reproductive cellular process GO:0048610 15 12 0,000 0,01557982 0,03435959 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,01557982 0,03432768 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,01557982 0,03429584 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,01557982 0,03426405 ! peroxisomal transport GO:0043574 22 12 0,000 0,01557982 0,03423233 ! mating GO:0007618 16 12 0,000 0,01557982 0,03420066 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01557982 0,03416905 ! heart looping GO:0001947 15 12 0,000 0,01557982 0,0341375 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,01557982 0,03410601 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,01557982 0,03407457 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,01557982 0,0340432 ! T cell selection GO:0045058 25 12 0,000 0,01557982 0,03401188 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01557982 0,03398062 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,01557982 0,03394942 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,01557982 0,03391827 ! plasma membrane organization GO:0007009 19 12 0,000 0,01557982 0,03388718 ! focal adhesion formation GO:0048041 28 12 0,000 0,01557982 0,03385615 ! mitotic spindle organization GO:0007052 16 12 0,000 0,01557982 0,03382517 ! cellular carbohydrate catabolic process GO:0044275 14 12 0,000 0,01557982 0,03379425 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,01557982 0,03376339 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01557982 0,03373259 ! monoamine transport GO:0015844 14 12 0,000 0,01557982 0,03370184 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,01557982 0,03367114 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,01557982 0,0336405 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01557982 0,03360992 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01557982 0,03357939 ! regulation of organ growth GO:0046620 14 12 0,000 0,01557982 0,03354892 ! vasoconstriction GO:0042310 18 12 0,000 0,01557982 0,03351851 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,01557982 0,03348815 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,01557982 0,03345784 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01557982 0,03342759 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01557982 0,03339739 ! histone deacetylation GO:0016575 14 12 0,000 0,01557982 0,03336725 ! histone acetylation GO:0016573 27 12 0,000 0,01557982 0,03333716 ! DNA methylation GO:0006306 19 12 0,000 0,01557982 0,03330713 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,01557982 0,03327715 ! protein sumoylation GO:0016925 14 12 0,000 0,01557982 0,03324722 ! chromatin silencing GO:0006342 23 12 0,000 0,01557982 0,03321735 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,01557982 0,03318753 ! gland morphogenesis GO:0022612 24 12 0,000 0,01557982 0,03315777 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,01557982 0,03312806 ! zymogen activation GO:0031638 16 12 0,000 0,01557982 0,0330984 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01557982 0,0330688 ! nucleosome positioning GO:0016584 13 12 0,000 0,01557982 0,03303924 ! T cell homeostasis GO:0043029 22 12 0,000 0,01557982 0,03300974 ! regulation of isotype switching GO:0045191 22 12 0,000 0,01557982 0,0329803 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,01557982 0,0329509 ! response to gamma radiation GO:0010332 21 12 0,000 0,01557982 0,03292156 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,01557982 0,03289227 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,01557982 0,03286303 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,01557982 0,03283385 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,01557982 0,03280471 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01557982 0,03277563 ! male genitalia development GO:0030539 15 12 0,000 0,01557982 0,0327466 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,01557982 0,03271762 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,01557982 0,03268869 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 0,000 0,01557982 0,03265982 ! developmental induction GO:0031128 16 12 0,000 0,01557982 0,03263099 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,01557982 0,03260222 ! response to cold GO:0009409 15 12 0,000 0,01557982 0,03257349 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,01557982 0,03254482 ! respiratory burst GO:0045730 22 13 0,000 0,01686755 0,03520378 ! lactation GO:0007595 22 13 0,000 0,01686755 0,03517284 ! tRNA modification GO:0006400 15 13 0,000 0,01686755 0,03514196 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,01686755 0,03511114 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,01686755 0,03508037 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01686755 0,03504965 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,01686755 0,03501898 ! water transport GO:0006833 21 13 0,000 0,01686755 0,03498837 GO:0042044|fluid transport, ! regulation of B cell proliferation GO:0030888 24 13 0,000 0,01686755 0,03495781 ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,01686755 0,03492731 ! copper ion transport GO:0006825 15 13 0,000 0,01686755 0,03489686 ! filopodium assembly GO:0046847 21 13 0,000 0,01686755 0,03486646 ! lipid localization GO:0010876 25 13 0,000 0,01686755 0,03483612 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,01686755 0,03480582 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,01686755 0,03477558 ! T cell proliferation GO:0042098 24 13 0,000 0,01686755 0,0347454 ! organelle fusion GO:0048284 29 13 0,000 0,01686755 0,03471526 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01686755 0,03468518 ! endocrine pancreas development GO:0031018 19 13 0,000 0,01686755 0,03465515 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,01686755 0,03462517 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,01686755 0,03459524 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,01686755 0,03456537 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,01686755 0,03453555 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,01686755 0,03450577 ! methionine metabolic process GO:0006555 16 13 0,000 0,01686755 0,03447605 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,01686755 0,03444638 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01686755 0,03441676 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,01686755 0,0343872 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,01686755 0,03435768 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,01686755 0,03432821 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,01686755 0,0342988 ! neutral amino acid transport GO:0015804 20 13 0,000 0,01686755 0,03426943 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,01686755 0,03424012 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,01686755 0,03421085 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,01686755 0,03418164 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,01686755 0,03415247 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01686755 0,03412336 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01686755 0,03409429 ! cellular pigmentation GO:0033059 24 13 0,000 0,01686755 0,03406527 ! histone methylation GO:0016571 16 13 0,000 0,01686755 0,03403631 ! regulation of epidermis development GO:0045682 21 13 0,000 0,01686755 0,03400739 ! oxygen transport GO:0015671 20 13 0,000 0,01686755 0,03397852 ! regulation of axon extension GO:0030516 26 13 0,000 0,01686755 0,0339497 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,01686755 0,03392093 ! detection of bacterium GO:0016045 13 13 0,000 0,01686755 0,03389221 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,01686755 0,03386353 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,01686755 0,03383491 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,01686755 0,03380633 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,01686755 0,0337778 ! actin filament polymerization GO:0030041 18 13 0,000 0,01686755 0,03374932 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,01815366 0,03629203 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,01815366 0,03626148 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,01815366 0,03623098 ! neuron maturation GO:0042551 24 14 0,000 0,01815366 0,03620054 ! regulation of S phase GO:0033261 25 14 0,000 0,01815366 0,03617014 ! regulation of chemokine production GO:0032642 18 14 0,000 0,01815366 0,0361398 ! myotube differentiation GO:0014902 21 14 0,000 0,01815366 0,0361095 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,01815366 0,03607926 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,01815366 0,03604907 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,01815366 0,03601893 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,01815366 0,03598884 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,01815366 0,0359588 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,01815366 0,03592881 ! RNA polyadenylation GO:0043631 21 14 0,000 0,01815366 0,03589886 ! gene silencing by RNA GO:0031047 22 14 0,000 0,01815366 0,03586897 ! response to cAMP GO:0051591 20 14 0,000 0,01815366 0,03583913 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,01815366 0,03580934 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,01815366 0,0357796 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,01815366 0,03574991 ! limbic system development GO:0021761 25 14 0,000 0,01815366 0,03572026 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,01815366 0,03569067 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,01815366 0,03566112 ! palate development GO:0060021 19 14 0,000 0,01815366 0,03563163 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,01815366 0,03560218 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,01815366 0,03557278 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,01815366 0,03554343 ! response to hexose stimulus GO:0009746 22 14 0,000 0,01815366 0,03551413 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,01815366 0,03548487 ! arginine metabolic process GO:0006525 17 14 0,000 0,01815366 0,03545567 ! glutamate metabolic process GO:0006536 21 14 0,000 0,01815366 0,03542651 ! glycine metabolic process GO:0006544 22 14 0,000 0,01815366 0,0353974 ! pituitary gland development GO:0021983 24 14 0,000 0,01815366 0,03536834 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,01815366 0,03533933 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,01815366 0,03531036 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,01815366 0,03528144 ! cytokine metabolic process GO:0042107 18 14 0,000 0,01815366 0,03525257 ! NAD metabolic process GO:0019674 25 14 0,000 0,01815366 0,03522374 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,01815366 0,03519497 ! regulation of heart rate GO:0002027 26 14 0,000 0,01815366 0,03516623 ! exocrine system development GO:0035272 29 14 0,000 0,01815366 0,03513755 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01815366 0,03510891 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,01815366 0,03508032 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,01815366 0,03505178 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,01815366 0,03502328 ! axon cargo transport GO:0008088 29 14 0,000 0,01815366 0,03499483 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,01815366 0,03496643 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,01815366 0,03493807 ! genitalia development GO:0048806 18 14 0,000 0,01815366 0,03490975 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,01815366 0,03488149 ! autonomic nervous system development GO:0048483 26 14 0,000 0,01815366 0,03485327 ! tissue regeneration GO:0042246 24 14 0,000 0,01815366 0,03482509 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,01815366 0,03479696 ! water homeostasis GO:0030104 23 14 0,000 0,01815366 0,03476888 ! cofactor transport GO:0051181 22 14 0,000 0,01815366 0,03474084 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,01815366 0,03471284 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,01815366 0,03468489 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01815366 0,03465699 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01815366 0,03462913 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,01815366 0,03460132 ! cell killing GO:0001906 22 14 0,000 0,01815366 0,03457355 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,01815366 0,03454582 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,01815366 0,03451814 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,01815366 0,0344905 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,01815366 0,03446291 ! microspike assembly GO:0030035 25 14 0,000 0,01815366 0,03443536 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,01815366 0,03440786 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,01943815 0,03681304 ! superoxide anion generation GO:0042554 19 15 0,000 0,01943815 0,03678368 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,01943815 0,03675437 ! skin development GO:0043588 28 15 0,000 0,01943815 0,03672511 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,01943815 0,03669589 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,01943815 0,03666672 ! inositol metabolic process GO:0006020 21 15 0,000 0,01943815 0,0366376 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,01943815 0,03660852 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,01943815 0,03657949 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,01943815 0,03655051 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,01943815 0,03652157 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01943815 0,03649267 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,01943815 0,03646382 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,01943815 0,03643502 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,01943815 0,03640627 ! response to osmotic stress GO:0006970 23 15 0,000 0,01943815 0,03637755 ! vesicle coating GO:0006901 26 15 0,000 0,01943815 0,03634889 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,01943815 0,03632027 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,01943815 0,03629169 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,01943815 0,03626316 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,01943815 0,03623467 ! bone mineralization GO:0030282 17 15 0,000 0,01943815 0,03620623 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,01943815 0,03617783 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,01943815 0,03614948 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,01943815 0,03612117 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,01943815 0,03609291 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,01943815 0,03606469 ! regulation of cellular pH GO:0030641 23 15 0,000 0,01943815 0,03603651 ! ribosome assembly GO:0042255 17 15 0,000 0,01943815 0,03600838 ! cerebellum development GO:0021549 19 15 0,000 0,01943815 0,03598029 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,01943815 0,03595225 ! mRNA splice site selection GO:0006376 33 15 0,000 0,01943815 0,03592425 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,01943815 0,03589629 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,01943815 0,03586838 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,01943815 0,03584051 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,01943815 0,03581268 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,01943815 0,0357849 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,01943815 0,03575716 ! muscle maintenance GO:0046716 21 15 0,000 0,01943815 0,03572946 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,01943815 0,03570181 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,01943815 0,0356742 ! intestinal absorption GO:0050892 22 15 0,000 0,01943815 0,03564663 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,01943815 0,0356191 ! dopamine metabolic process GO:0042417 32 15 0,000 0,01943815 0,03559162 ! gas transport GO:0015669 23 15 0,000 0,01943815 0,03556418 ! regulation of RNA stability GO:0043487 31 15 0,000 0,01943815 0,03553678 ! organic cation transport GO:0015695 19 15 0,000 0,01943815 0,03550942 ! heme biosynthetic process GO:0006783 22 15 0,000 0,01943815 0,03548211 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,01943815 0,03545483 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,01943815 0,0354276 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,01943815 0,03540041 ! release of cytochrome c from mitochondria GO:0001836 29 15 0,000 0,01943815 0,03537327 ! cilium assembly GO:0042384 22 15 0,000 0,01943815 0,03534616 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,01943815 0,0353191 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,01943815 0,03529207 ! peptide hormone processing GO:0016486 23 15 0,000 0,01943815 0,03526509 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,01943815 0,03523815 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,02072103 0,03753512 ! bone remodeling GO:0046849 24 16 0,000 0,02072103 0,03750649 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,02072103 0,0374779 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,02072103 0,03744936 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,02072103 0,03742086 ! bile acid metabolic process GO:0008206 23 16 0,000 0,02072103 0,0373924 ! axis specification GO:0009798 26 16 0,000 0,02072103 0,03736399 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,02072103 0,03733561 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,02072103 0,03730729 ! positive regulation of cell growth GO:0030307 22 16 0,000 0,02072103 0,037279 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02072103 0,03725076 ! centrosome cycle GO:0007098 18 16 0,000 0,02072103 0,03722256 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,02072103 0,03719441 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,02072103 0,03716629 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,02072103 0,03713822 ! cellular response to starvation GO:0009267 26 16 0,000 0,02072103 0,03711019 ! DNA integration GO:0015074 25 16 0,000 0,02072103 0,03708221 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,02072103 0,03705426 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,02072103 0,03702636 ! regulation of exocytosis GO:0017157 28 16 0,000 0,02072103 0,0369985 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,02072103 0,03697068 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,02072103 0,0369429 ! regulation of vasodilation GO:0042312 26 16 0,000 0,02072103 0,03691517 ! DNA replication initiation GO:0006270 26 16 0,000 0,02072103 0,03688748 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,02072103 0,03685982 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,02072103 0,03683221 ! neuron recognition GO:0008038 27 16 0,000 0,02072103 0,03680464 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,02072103 0,03677712 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,02072103 0,03674963 ! G1 phase GO:0051318 28 16 0,000 0,02072103 0,03672218 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,02072103 0,03669478 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02072103 0,03666742 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,02072103 0,03664009 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,02072103 0,03661281 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,02072103 0,03658557 ! NADP metabolic process GO:0006739 22 16 0,000 0,02072103 0,03655837 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,02072103 0,03653121 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,02072103 0,03650409 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,02072103 0,03647701 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,02072103 0,03644997 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02072103 0,03642297 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,02072103 0,03639601 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,02072103 0,03636909 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,02072103 0,03634221 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,02072103 0,03631537 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,02072103 0,03628856 ! defense response to virus GO:0051607 28 16 0,000 0,02072103 0,0362618 ! peptide hormone secretion GO:0030072 26 16 0,000 0,02072103 0,03623508 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02200229 0,03844731 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02200229 0,03841901 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02200229 0,03839077 ! zinc ion transport GO:0006829 22 17 0,000 0,02200229 0,03836256 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02200229 0,03833439 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02200229 0,03830627 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02200229 0,03827818 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02200229 0,03825014 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02200229 0,03822214 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02200229 0,03819418 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02200229 0,03816626 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02200229 0,03813838 ! adult walking behavior GO:0007628 30 17 0,000 0,02200229 0,03811054 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02200229 0,03808274 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02200229 0,03805499 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02200229 0,03802727 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 25 17 0,000 0,02200229 0,03799959 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02200229 0,03797196 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02200229 0,03794436 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02200229 0,03791681 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02200229 0,03788929 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02200229 0,03786181 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02200229 0,03783438 ! cerebral cortex development GO:0021987 34 17 0,000 0,02200229 0,03780698 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02200229 0,03777962 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02200229 0,03775231 ! fructose metabolic process GO:0006000 24 17 0,000 0,02200229 0,03772503 ! membrane budding GO:0006900 30 17 0,000 0,02200229 0,03769779 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02200229 0,03767059 ! L-amino acid transport GO:0015807 27 17 0,000 0,02200229 0,03764343 ! regulation of protein binding GO:0043393 29 17 0,000 0,02200229 0,03761631 ! peptide secretion GO:0002790 30 17 0,000 0,02200229 0,03758923 ! stem cell differentiation GO:0048863 40 17 0,000 0,02200229 0,03756219 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02200229 0,03753518 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02200229 0,03750822 ! protein export from nucleus GO:0006611 26 17 0,000 0,02200229 0,03748129 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02200229 0,03745441 ! diencephalon development GO:0021536 27 17 0,000 0,02200229 0,03742756 ! oogenesis GO:0048477 25 17 0,000 0,02200229 0,03740075 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02200229 0,03737397 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02200229 0,03734724 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02200229 0,03732054 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02200229 0,03729389 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02200229 0,03726727 ! steroid catabolic process GO:0006706 24 17 0,000 0,02200229 0,03724069 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02200229 0,03721414 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02200229 0,03718764 ! nerve development GO:0021675 20 17 0,000 0,02200229 0,03716117 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02200229 0,03713474 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02200229 0,03710834 ! protein secretion GO:0009306 32 18 0,000 0,02328194 0,03923867 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,02328194 0,03921082 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,02328194 0,03918302 ! negative regulation of defense response GO:0031348 21 18 0,000 0,02328194 0,03915525 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,02328194 0,03912752 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,02328194 0,03909982 ! metencephalon development GO:0022037 25 18 0,000 0,02328194 0,03907217 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,02328194 0,03904456 ! hormone secretion GO:0046879 28 18 0,000 0,02328194 0,03901699 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,02328194 0,03898945 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,02328194 0,03896196 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,02328194 0,0389345 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,02328194 0,03890708 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,02328194 0,0388797 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02328194 0,03885236 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,02328194 0,03882505 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,02328194 0,03879779 ! glial cell development GO:0021782 31 18 0,000 0,02328194 0,03877056 ! keratinization GO:0031424 19 18 0,000 0,02328194 0,03874337 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,02328194 0,03871622 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,02328194 0,03868911 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,02328194 0,03866204 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,02328194 0,038635 ! vacuolar transport GO:0007034 26 18 0,000 0,02328194 0,038608 ! pigmentation during development GO:0048066 35 18 0,000 0,02328194 0,03858104 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,02328194 0,03855412 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,02328194 0,03852723 ! fucose metabolic process GO:0006004 27 18 0,000 0,02328194 0,03850038 ! actin filament bundle formation GO:0051017 30 18 0,000 0,02328194 0,03847357 ! body fluid secretion GO:0007589 27 18 0,000 0,02328194 0,0384468 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,02328194 0,03842006 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,02328194 0,03839336 ! negative regulation of immune response GO:0050777 33 18 0,000 0,02328194 0,0383667 ! heart process GO:0003015 32 18 0,000 0,02328194 0,03834008 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,02328194 0,03831349 ! sensory perception of pain GO:0019233 26 18 0,000 0,02328194 0,03828694 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,02328194 0,03826042 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,02328194 0,03823395 ! somitogenesis GO:0001756 25 18 0,000 0,02328194 0,0382075 ! neural crest cell migration GO:0001755 28 18 0,000 0,02328194 0,0381811 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,02328194 0,03815473 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,02328194 0,0381284 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,02328194 0,0381021 ! synaptogenesis GO:0007416 28 18 0,000 0,02328194 0,03807585 ! cell-cell junction organization GO:0045216 28 18 0,000 0,02328194 0,03804962 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02328194 0,03802344 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,02328194 0,03799728 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,02328194 0,03797117 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,02328194 0,03794509 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,02328194 0,03791905 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,02328194 0,03789304 ! gut development GO:0048565 29 18 0,000 0,02328194 0,03786707 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,02328194 0,03784113 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,02328194 0,03781523 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,02328194 0,03778937 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,02455998 0,03983653 ! positive regulation of translation GO:0045727 29 19 0,000 0,02455998 0,03980932 ! positive regulation of cell size GO:0045793 26 19 0,000 0,02455998 0,03978215 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,02455998 0,03975501 ! glycerol metabolic process GO:0006071 22 19 0,000 0,02455998 0,03972791 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,02455998 0,03970085 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,02455998 0,03967382 ! endothelial cell migration GO:0043542 24 19 0,000 0,02455998 0,03964683 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,02455998 0,03961988 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,02455998 0,03959296 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,02455998 0,03956608 ! memory GO:0007613 28 19 0,000 0,02455998 0,03953924 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 0,000 0,02455998 0,03951244 ! pancreas development GO:0031016 27 19 0,000 0,02455998 0,03948567 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,02455998 0,03945893 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,02455998 0,03943223 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,02455998 0,03940557 ! central nervous system neuron development GO:0021954 33 19 0,000 0,02455998 0,03937895 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,02455998 0,03935236 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,02455998 0,0393258 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,02455998 0,03929929 ! heme metabolic process GO:0042168 29 19 0,000 0,02455998 0,03927281 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,02455998 0,03924636 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,02455998 0,03921995 ! response to fungus GO:0009620 21 19 0,000 0,02455998 0,03919357 ! peptide cross-linking GO:0018149 35 19 0,000 0,02455998 0,03916723 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,02455998 0,03914093 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,02455998 0,03911466 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,02455998 0,03908843 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,02455998 0,03906223 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,02455998 0,03903606 ! vitamin transport GO:0051180 26 19 0,000 0,02455998 0,03900994 ! sarcomere organization GO:0045214 26 19 0,000 0,02455998 0,03898384 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,02455998 0,03895778 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,02455998 0,03893176 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,02455998 0,03890577 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,02455998 0,03887982 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,02455998 0,0388539 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,02455998 0,03882801 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,02583642 0,04081879 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,02583642 0,04079163 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,02583642 0,04076451 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,02583642 0,04073742 ! lipid phosphorylation GO:0046834 28 20 0,000 0,02583642 0,04071037 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,02583642 0,04068336 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,02583642 0,04065638 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,02583642 0,04062944 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,02583642 0,04060253 ! response to alkaloid GO:0043279 34 20 0,000 0,02583642 0,04057566 ! sensory perception of taste GO:0050909 26 20 0,000 0,02583642 0,04054882 ! response to retinoic acid GO:0032526 27 20 0,000 0,02583642 0,04052202 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,02583642 0,04049526 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,02583642 0,04046853 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,02583642 0,04044183 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,02583642 0,04041517 ! chromosome condensation GO:0030261 32 20 0,000 0,02583642 0,04038855 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,02583642 0,04036196 ! sex determination GO:0007530 32 20 0,000 0,02583642 0,04033541 ! plasma membrane fusion GO:0045026 24 20 0,000 0,02583642 0,04030889 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,02583642 0,0402824 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,02583642 0,04025595 ! cytolysis GO:0019835 21 20 0,000 0,02583642 0,04022954 ! renal system process GO:0003014 35 20 0,000 0,02583642 0,04020316 ! vasodilation GO:0042311 36 20 0,000 0,02583642 0,04017681 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,02583642 0,0401505 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,02583642 0,04012423 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,02583642 0,04009798 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,02583642 0,04007178 ! hormone transport GO:0009914 30 20 0,000 0,02583642 0,0400456 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,02583642 0,04001946 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,02583642 0,03999336 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,02583642 0,03996729 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,02583642 0,03994125 ! sperm-egg recognition GO:0035036 24 20 0,000 0,02583642 0,03991525 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,02583642 0,03988928 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,02583642 0,03986334 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,02711124 0,04180311 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,02711124 0,04177596 ! positive regulation of fibroblast proliferation GO:0048146 30 21 0,000 0,02711124 0,04174885 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02711124 0,04172178 ! positive regulation of ossification GO:0045778 34 21 0,000 0,02711124 0,04169474 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 0,000 0,02711124 0,04166773 ! iron ion transport GO:0006826 49 21 0,000 0,02711124 0,04164076 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,02711124 0,04161383 ! microtubule-based transport GO:0010970 41 21 0,000 0,02711124 0,04158693 ! vesicle docking GO:0048278 28 21 0,000 0,02711124 0,04156007 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,02711124 0,04153323 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,02711124 0,04150644 ! apoptotic mitochondrial changes GO:0008637 42 21 0,000 0,02711124 0,04147968 ! response to ethanol GO:0045471 38 21 0,000 0,02711124 0,04145295 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,02711124 0,04142626 ! smooth muscle contraction GO:0006939 39 21 0,000 0,02711124 0,0413996 ! glutamine metabolic process GO:0006541 29 21 0,000 0,02711124 0,04137298 ! response to vitamin A GO:0033189 28 21 0,000 0,02711124 0,04134639 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,02711124 0,04131983 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,02711124 0,04129331 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,02711124 0,04126683 ! response to starvation GO:0042594 35 21 0,000 0,02711124 0,04124037 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,02711124 0,04121395 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,02711124 0,04118757 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,02711124 0,04116122 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,02711124 0,0411349 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,02711124 0,04110861 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,02711124 0,04108236 ! visual learning GO:0008542 38 21 0,000 0,02711124 0,04105615 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 0,000 0,02711124 0,04102996 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,02711124 0,04100381 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,02711124 0,04097769 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02711124 0,04095161 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,02711124 0,04092556 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,02711124 0,04089954 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02711124 0,04087356 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,02711124 0,04084761 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,02711124 0,04082169 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02711124 0,0407958 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,02711124 0,04076995 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,02711124 0,04074413 ! embryonic pattern specification GO:0009880 34 22 0,000 0,02838447 0,04263059 ! regulation of cell killing GO:0031341 37 22 0,000 0,02838447 0,04260363 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,02838447 0,0425767 ! gluconeogenesis GO:0006094 26 22 0,000 0,02838447 0,0425498 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,02838447 0,04252294 ! viral genome replication GO:0019079 31 22 0,000 0,02838447 0,04249611 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,02838447 0,04246932 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,02838447 0,04244256 ! protein amino acid acylation GO:0043543 42 22 0,000 0,02838447 0,04241583 ! response to vitamin GO:0033273 31 22 0,000 0,02838447 0,04238914 ! molting cycle process GO:0022404 43 22 0,000 0,02838447 0,04236248 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,02838447 0,04233585 ! regeneration GO:0031099 37 22 0,000 0,02838447 0,04230926 ! phototransduction GO:0007602 29 22 0,000 0,02838447 0,0422827 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,02838447 0,04225617 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,02838447 0,04222968 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,02838447 0,04220322 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,02838447 0,04217679 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,02838447 0,0421504 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,02838447 0,04212404 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,02838447 0,04209771 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,02838447 0,04207142 ! pallium development GO:0021543 43 22 0,000 0,02838447 0,04204515 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,02838447 0,04201893 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,02838447 0,04199273 ! platelet activation GO:0030168 33 22 0,000 0,02838447 0,04196657 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,02838447 0,04194043 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,02838447 0,04191434 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,02838447 0,04188827 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,02838447 0,04186224 ! cell-cell recognition GO:0009988 28 22 0,000 0,02838447 0,04183623 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,02838447 0,04181027 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,02838447 0,04178433 ! neural tube closure GO:0001843 35 22 0,000 0,02838447 0,04175842 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 26 22 0,000 0,02838447 0,04173255 ! regulation of multi-organism process GO:0043900 35 22 0,000 0,02838447 0,04170671 ! protein tetramerization GO:0051262 43 22 0,000 0,02838447 0,0416809 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,02965609 0,04352127 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,02965609 0,04349437 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,02965609 0,04346751 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,02965609 0,04344067 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,02965609 0,04341388 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,02965609 0,04338711 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,02965609 0,04336038 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,02965609 0,04333368 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,02965609 0,04330701 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,02965609 0,04328038 ! tube lumen formation GO:0035148 37 23 0,000 0,02965609 0,04325377 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,02965609 0,04322721 ! dendrite development GO:0016358 41 23 0,000 0,02965609 0,04320067 ! vasculogenesis GO:0001570 38 23 0,000 0,02965609 0,04317417 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,02965609 0,0431477 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,02965609 0,04312126 ! lysosome organization GO:0007040 41 23 0,000 0,02965609 0,04309485 ! digestive system process GO:0022600 35 23 0,000 0,02965609 0,04306848 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,02965609 0,04304214 ! vesicle targeting GO:0006903 35 23 0,000 0,02965609 0,04301583 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,02965609 0,04298955 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,02965609 0,0429633 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,02965609 0,04293709 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,02965609 0,04291091 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,02965609 0,04288476 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,02965609 0,04285864 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,02965609 0,04283256 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,02965609 0,0428065 ! membrane depolarization GO:0051899 40 23 0,000 0,02965609 0,04278048 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02965609 0,04275449 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,02965609 0,04272853 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,02965609 0,0427026 ! DNA modification GO:0006304 33 23 0,000 0,02965609 0,04267671 ! collagen fibril organization GO:0030199 50 23 0,000 0,02965609 0,04265084 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,02965609 0,04262501 ! cellular response to extracellular stimulus GO:0031668 37 23 0,000 0,02965609 0,04259921 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,02965609 0,04257344 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,02965609 0,0425477 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,02965609 0,04252199 ! positive regulation of B cell activation GO:0050871 36 23 0,000 0,02965609 0,04249631 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02965609 0,04247066 ! collagen catabolic process GO:0030574 29 23 0,000 0,02965609 0,04244505 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,02965609 0,04241946 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,02965609 0,04239391 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,02965609 0,04236839 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,02965609 0,0423429 ! blastocyst development GO:0001824 41 23 0,000 0,02965609 0,04231743 ! actin filament-based movement GO:0030048 37 23 0,000 0,02965609 0,042292 ! protein stabilization GO:0050821 34 23 0,000 0,02965609 0,0422666 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,03092611 0,04405021 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,03092611 0,04402378 ! myelination GO:0042552 39 24 0,000 0,03092611 0,04399739 ! initiation of viral infection GO:0019059 47 24 0,000 0,03092611 0,04397103 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,03092611 0,0439447 ! leukocyte adhesion GO:0007159 49 24 0,000 0,03092611 0,0439184 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,03092611 0,04389213 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,03092611 0,0438659 ! visual behavior GO:0007632 42 24 0,000 0,03092611 0,04383969 ! spinal cord development GO:0021510 41 24 0,000 0,03092611 0,04381352 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,03092611 0,04378738 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 0,000 0,03092611 0,04376127 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,03092611 0,04373519 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,03092611 0,04370914 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,03092611 0,04368312 ! cell aging GO:0007569 38 24 0,000 0,03092611 0,04365714 ! osteoblast differentiation GO:0001649 43 24 0,000 0,03092611 0,04363118 ! response to toxin GO:0009636 38 24 0,000 0,03092611 0,04360526 ! primary neural tube formation GO:0014020 37 24 0,000 0,03092611 0,04357936 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,03092611 0,0435535 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,03092611 0,04352767 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,03092611 0,04350187 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,03092611 0,0434761 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,03092611 0,04345035 ! pentose metabolic process GO:0019321 33 24 0,000 0,03092611 0,04342464 ! immunoglobulin production GO:0002377 37 24 0,000 0,03092611 0,04339896 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,03092611 0,04337331 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,03092611 0,0433477 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,03092611 0,04332211 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,03092611 0,04329655 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,03092611 0,04327102 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,03092611 0,04324552 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,03092611 0,04322005 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,03092611 0,04319461 ! regulation of fibroblast proliferation GO:0048145 39 25 0,000 0,03219453 0,04493977 ! neuron fate commitment GO:0048663 38 25 0,000 0,03219453 0,04491335 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,03219453 0,04488696 ! superoxide metabolic process GO:0006801 33 25 0,000 0,03219453 0,04486061 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,03219453 0,04483428 GO:0050908|detection of light stimulus involved in visual perception, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,03219453 0,04480798 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,03219453 0,04478172 ! vacuole organization GO:0007033 43 25 0,000 0,03219453 0,04475548 ! receptor metabolic process GO:0043112 40 25 0,000 0,03219453 0,04472928 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,03219453 0,04470311 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,03219453 0,04467697 ! regulation of behavior GO:0050795 45 25 0,000 0,03219453 0,04465085 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,03219453 0,04462477 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,03219453 0,04459872 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,03219453 0,0445727 ! negative regulation of phosphorylation GO:0042326 46 25 0,000 0,03219453 0,04454671 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03219453 0,04452075 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,03219453 0,04449482 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,03219453 0,04446892 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,03219453 0,04444306 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,03219453 0,04441722 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,03219453 0,04439141 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,03219453 0,04436563 ! regulation of amine transport GO:0051952 44 25 0,000 0,03219453 0,04433988 ! liver development GO:0001889 44 25 0,000 0,03219453 0,04431416 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,03346135 0,04603118 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,03346135 0,04600451 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,03346135 0,04597787 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,03346135 0,04595127 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,03346135 0,04592469 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,03346135 0,04589814 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,03346135 0,04587163 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,03346135 0,04584514 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,03346135 0,04581869 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,03346135 0,04579227 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,03346135 0,04576587 ! sperm motility GO:0030317 31 26 0,000 0,03346135 0,04573951 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,03346135 0,04571318 ! male gonad development GO:0008584 39 26 0,000 0,03346135 0,04568687 ! neural crest cell development GO:0014032 44 26 0,000 0,03346135 0,0456606 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,03346135 0,04563436 ! cell fate determination GO:0001709 54 26 0,000 0,03346135 0,04560815 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,03346135 0,04558197 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,03346135 0,04555582 ! detection of visible light GO:0009584 33 26 0,000 0,03346135 0,04552969 ! spermatid development GO:0007286 40 26 0,000 0,03346135 0,0455036 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,03346135 0,04547754 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,03346135 0,04545151 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,03346135 0,04542551 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,03346135 0,04539954 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03472658 0,04708925 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,03472658 0,04706235 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,03472658 0,04703549 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,03472658 0,04700866 ! membrane docking GO:0022406 40 27 0,000 0,03472658 0,04698186 ! circadian rhythm GO:0007623 44 27 0,000 0,03472658 0,04695509 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,03472658 0,04692835 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,03472658 0,04690164 ! autophagy GO:0006914 36 27 0,000 0,03472658 0,04687496 ! myofibril assembly GO:0030239 40 27 0,000 0,03472658 0,04684831 GO:0055002|striated muscle cell development, ! negative regulation of phosphorus metabolic process GO:0010563 51 27 0,000 0,03472658 0,04682169 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,03472658 0,0467951 ! peptide transport GO:0015833 46 27 0,000 0,03472658 0,04676855 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,03472658 0,04674202 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,03472658 0,04671552 ! negative regulation of cell development GO:0010721 67 27 0,000 0,03472658 0,04668905 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,03472658 0,04666262 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,03472658 0,04663621 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,03472658 0,04660983 ! detection of light stimulus GO:0009583 35 27 0,000 0,03472658 0,04658348 ! glutathione metabolic process GO:0006749 35 27 0,000 0,03472658 0,04655716 ! lipid oxidation GO:0034440 39 27 0,000 0,03472658 0,04653087 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,03472658 0,04650462 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,03472658 0,04647839 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,03472658 0,04645219 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,03599022 0,04811538 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,03599022 0,04808828 ! translational initiation GO:0006413 48 28 0,000 0,03599022 0,04806122 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,03599022 0,04803419 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,03599022 0,04800719 ! regulation of pH GO:0006885 40 28 0,000 0,03599022 0,04798022 ! catechol metabolic process GO:0009712 46 28 0,000 0,03599022 0,04795328 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,03599022 0,04792637 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,03599022 0,04789949 ! iron ion homeostasis GO:0055072 49 28 0,000 0,03599022 0,04787264 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,03599022 0,04784582 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,03599022 0,04781903 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,03599022 0,04779227 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,03599022 0,04776554 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,03599022 0,04773884 ! gene silencing GO:0016458 47 28 0,000 0,03599022 0,04771217 ! regulation of coagulation GO:0050818 42 28 0,000 0,03599022 0,04768553 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,03725227 0,04933015 ! phenol metabolic process GO:0018958 47 29 0,000 0,03725227 0,04930264 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,03725227 0,04927516 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,03725227 0,0492477 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,03725227 0,04922028 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,03725227 0,04919289 ! cholesterol transport GO:0030301 48 29 0,000 0,03725227 0,04916553 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,03725227 0,0491382 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,03725227 0,04911091 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,03725227 0,04908364 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,03725227 0,0490564 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,03725227 0,04902919 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,03725227 0,04900201 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,03725227 0,04897486 ! response to ionizing radiation GO:0010212 55 29 0,000 0,03725227 0,04894775 ! muscle cell development GO:0055001 42 29 0,000 0,03725227 0,04892066 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,03725227 0,0488936 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,03725227 0,04886657 ! mesoderm formation GO:0001707 52 29 0,000 0,03725227 0,04883957 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,03725227 0,04881261 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,03725227 0,04878567 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,03725227 0,04875876 ! ensheathment of neurons GO:0007272 48 29 0,000 0,03725227 0,04873188 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,03725227 0,04870503 ! spermatid differentiation GO:0048515 45 29 0,000 0,03725227 0,04867821 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,03725227 0,04865142 ! neural tube formation GO:0001841 46 29 0,000 0,03725227 0,04862466 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,03851273 0,05024227 ! organic anion transport GO:0015711 50 30 0,000 0,03851273 0,05021467 ! cell junction assembly GO:0034329 65 30 0,000 0,03851273 0,05018709 ! acute-phase response GO:0006953 49 30 0,000 0,03851273 0,05015955 ! segmentation GO:0035282 43 30 0,000 0,03851273 0,05013203 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,03851273 0,05010455 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,03851273 0,05007709 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,03851273 0,05004967 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,03851273 0,05002228 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,03851273 0,04999491 ! ceramide metabolic process GO:0006672 47 30 0,000 0,03851273 0,04996758 ! formation of primary germ layer GO:0001704 54 30 0,000 0,03851273 0,04994027 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,03851273 0,049913 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,03851273 0,04988575 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,03851273 0,04985854 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,03851273 0,04983135 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,03851273 0,04980419 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,03851273 0,04977707 ! response to heat GO:0009408 43 30 0,000 0,03851273 0,04974997 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,03851273 0,0497229 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,0397716 0,05132028 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,0397716 0,05129239 ! post-embryonic development GO:0009791 50 31 0,000 0,0397716 0,05126453 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,0397716 0,0512367 ! regulation of innate immune response GO:0045088 42 31 0,000 0,0397716 0,0512089 ! ovulation cycle process GO:0022602 46 31 0,000 0,0397716 0,05118113 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,0397716 0,05115339 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,0397716 0,05112568 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,0397716 0,051098 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,0397716 0,05107035 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,0397716 0,05104273 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,0397716 0,05101513 ! hexose biosynthetic process GO:0019319 37 31 0,000 0,0397716 0,05098757 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,0397716 0,05096004 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,0397716 0,05093254 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,0397716 0,05090507 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,0397716 0,05087763 ! tissue homeostasis GO:0001894 45 31 0,000 0,0397716 0,05085021 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,04102888 0,05242948 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,04102888 0,05240126 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,04102888 0,05237307 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,04102888 0,05234491 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,04102888 0,05231679 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,04102888 0,05228869 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,04102888 0,05226062 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,04102888 0,05223259 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,04102888 0,05220458 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,04102888 0,0521766 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,04102888 0,05214866 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,04102888 0,05212074 ! telencephalon development GO:0021537 59 32 0,000 0,04102888 0,05209285 ! ovulation cycle GO:0042698 48 32 0,000 0,04102888 0,05206499 ! cofactor catabolic process GO:0051187 52 32 0,000 0,04102888 0,05203717 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,04102888 0,05200937 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,04102888 0,0519816 ! placenta development GO:0001890 45 32 0,000 0,04102888 0,05195386 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,04102888 0,05192615 ! vesicle localization GO:0051648 50 32 0,000 0,04102888 0,05189848 ! regulation of muscle development GO:0048634 52 33 0,000 0,04228459 0,05345835 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,04228459 0,05342989 ! negative regulation of secretion GO:0051048 53 33 0,000 0,04228459 0,05340145 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,04228459 0,05337304 ! glial cell differentiation GO:0010001 65 33 0,000 0,04228459 0,05334467 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,04228459 0,05331633 ! sister chromatid segregation GO:0000819 48 33 0,000 0,04228459 0,05328801 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,04228459 0,05325973 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,04228459 0,05323147 ! spindle organization GO:0007051 39 33 0,000 0,04228459 0,05320325 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,04228459 0,05317505 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,04228459 0,05314689 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,04228459 0,05311875 ! protein targeting to membrane GO:0006612 63 33 0,000 0,04228459 0,05309065 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,04228459 0,05306257 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,04228459 0,05303453 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,04228459 0,05300651 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,04228459 0,05297852 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,04228459 0,05295057 ! cytokine production GO:0001816 49 33 0,000 0,04228459 0,05292264 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,04228459 0,05289474 ! RNA modification GO:0009451 43 33 0,000 0,04228459 0,05286687 ! regulation of B cell activation GO:0050864 55 33 0,000 0,04228459 0,05283903 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,04228459 0,05281122 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 0,000 0,04353871 0,05434895 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,04353871 0,05432038 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,04353871 0,05429183 ! actomyosin structure organization GO:0031032 48 34 0,000 0,04353871 0,05426332 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,04353871 0,05423483 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,04353871 0,05420638 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,04353871 0,05417795 ! positive regulation of cell development GO:0010720 58 34 0,000 0,04353871 0,05414956 ! cell fate specification GO:0001708 49 34 0,000 0,04353871 0,05412119 ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 0,000 0,04353871 0,05409286 ! peripheral nervous system development GO:0007422 58 34 0,000 0,04353871 0,05406455 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,04353871 0,05403627 ! adult locomotory behavior GO:0008344 54 34 0,000 0,04353871 0,05400803 ! monosaccharide biosynthetic process GO:0046364 40 34 0,000 0,04353871 0,05397981 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,04479125 0,05550373 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,04479125 0,05547476 ! collagen metabolic process GO:0032963 47 35 0,000 0,04479125 0,05544582 ! cell junction organization GO:0034330 72 35 0,000 0,04479125 0,05541691 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,04479125 0,05538804 ! metanephros development GO:0001656 61 35 0,000 0,04479125 0,05535919 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,04479125 0,05533037 ! female gonad development GO:0008585 55 35 0,000 0,04479125 0,05530158 ! lipid homeostasis GO:0055088 63 35 0,000 0,04479125 0,05527282 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,04479125 0,0552441 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04479125 0,0552154 ! negative regulation of hydrolase activity GO:0051346 56 35 0,000 0,04479125 0,05518673 ! hindbrain development GO:0030902 56 35 0,000 0,04479125 0,05515809 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,04479125 0,05512948 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,04479125 0,0551009 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,04479125 0,05507235 ! cytokinesis GO:0000910 57 35 0,000 0,04479125 0,05504383 ! embryonic organ development GO:0048568 53 35 0,000 0,04479125 0,05501534 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,04479125 0,05498688 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,04479125 0,05495845 ! protein homooligomerization GO:0051260 59 35 0,000 0,04479125 0,05493005 ! meiosis I GO:0007127 61 36 0,000 0,04604222 0,05643501 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,04604222 0,05640588 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,04604222 0,05637677 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,04604222 0,0563477 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,04604222 0,05631865 ! spliceosome assembly GO:0000245 65 36 0,000 0,04604222 0,05628964 ! mismatch repair GO:0006298 42 36 0,000 0,04604222 0,05626065 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,04604222 0,0562317 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,04604222 0,05620277 ! regulation of proteolysis GO:0030162 53 36 0,000 0,04604222 0,05617387 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,04604222 0,05614501 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 53 36 0,000 0,04604222 0,05611617 ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,04604222 0,05608736 ! eye morphogenesis GO:0048592 64 36 0,000 0,04604222 0,05605859 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,04604222 0,05602984 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,04729161 0,05752075 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,04729161 0,05749128 ! mammary gland development GO:0030879 73 37 0,000 0,04729161 0,05746185 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,04729161 0,05743244 ! ear morphogenesis GO:0042471 50 37 0,000 0,04729161 0,05740306 ! odontogenesis GO:0042476 60 37 0,000 0,04729161 0,05737372 ! negative regulation of binding GO:0051100 59 37 0,000 0,04729161 0,0573444 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,04729161 0,05731511 ! tissue remodeling GO:0048771 65 37 0,000 0,04729161 0,05728585 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,04729161 0,05725663 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,04729161 0,05722743 ! keratinocyte differentiation GO:0030216 55 37 0,000 0,04729161 0,05719826 ! natural killer cell activation GO:0030101 45 37 0,000 0,04729161 0,05716912 ! polyol metabolic process GO:0019751 47 37 0,000 0,04729161 0,05714001 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,04729161 0,05711094 ! glucan metabolic process GO:0044042 54 37 0,000 0,04729161 0,05708189 GO:0006073|cellular glucan metabolic process, ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,04853943 0,05855824 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,04853943 0,05852848 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,04853943 0,05849876 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,04853943 0,05846907 ! feeding behavior GO:0007631 50 38 0,000 0,04853943 0,0584394 ! organic ether metabolic process GO:0018904 51 38 0,000 0,04853943 0,05840977 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,04853943 0,05838016 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,04853943 0,05835059 GO:0046660|female sex differentiation, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,04853943 0,05832104 ! ion transmembrane transport GO:0034220 58 38 0,000 0,04853943 0,05829153 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,04853943 0,05826204 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,04853943 0,05823259 ! neuron migration GO:0001764 59 38 0,000 0,04853943 0,05820316 ! maintenance of protein location GO:0045185 72 38 0,000 0,04853943 0,05817377 ! pigment metabolic process GO:0042440 66 38 0,000 0,04853943 0,0581444 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,04853943 0,05811506 ! mRNA catabolic process GO:0006402 58 39 0,000 0,04978567 0,0595771 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,04978567 0,05954708 ! establishment or maintenance of cell polarity GO:0007163 74 39 0,000 0,04978567 0,05951708 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,04978567 0,05948711 ! neural tube development GO:0021915 58 39 0,000 0,04978567 0,05945717 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,04978567 0,05942726 ! regulation of protein stability GO:0031647 58 39 0,000 0,04978567 0,05939739 ! female gamete generation GO:0007292 50 39 0,000 0,04978567 0,05936754 ! aerobic respiration GO:0009060 56 39 0,000 0,04978567 0,05933772 ! positive regulation of leukocyte proliferation GO:0070665 64 39 0,000 0,04978567 0,05930793 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,04978567 0,05927817 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,05103035 0,0607297 ! Notch signaling pathway GO:0007219 64 40 0,000 0,05103035 0,06069926 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,05103035 0,06066885 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,05103035 0,06063847 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,05103035 0,06060812 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,05103035 0,0605778 ! alcohol biosynthetic process GO:0046165 48 40 0,000 0,05103035 0,06054751 ! phagocytosis GO:0006909 65 40 0,000 0,05103035 0,06051725 ! mesenchymal cell development GO:0014031 70 40 0,000 0,05103035 0,06048702 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,05103035 0,06045682 ! B cell differentiation GO:0030183 70 40 0,000 0,05103035 0,06042665 ! pigmentation GO:0043473 81 40 0,000 0,05103035 0,06039652 ! developmental growth GO:0048589 70 40 0,000 0,05103035 0,06036641 ! synapse organization GO:0050808 61 40 0,000 0,05103035 0,06033633 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,05227346 0,06177535 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,05227346 0,0617446 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,05227346 0,06171389 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,05227346 0,0616832 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,05227346 0,06165254 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,05227346 0,06162191 ! cell growth GO:0016049 71 41 0,000 0,05227346 0,06159132 ! maintenance of location in cell GO:0051651 77 41 0,000 0,05227346 0,06156075 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,053515 0,06299161 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,053515 0,06296038 ! learning GO:0007612 75 42 0,000 0,053515 0,06292918 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,053515 0,06289801 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,053515 0,06286688 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,053515 0,06283577 ! gliogenesis GO:0042063 85 42 0,000 0,053515 0,06280469 ! endosome transport GO:0016197 74 42 0,000 0,053515 0,06277365 ! induction of apoptosis by intracellular signals GO:0008629 78 42 0,000 0,053515 0,06274263 ! male sex differentiation GO:0046661 62 42 0,000 0,053515 0,06271165 ! double-strand break repair GO:0006302 75 42 0,000 0,053515 0,0626807 ! epidermal cell differentiation GO:0009913 61 42 0,000 0,053515 0,06264977 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,053515 0,06261888 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,053515 0,06258802 ! mitochondrial transport GO:0006839 66 43 0,000 0,05475498 0,06400668 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,05475498 0,06397516 ! energy reserve metabolic process GO:0006112 67 43 0,000 0,05475498 0,06394368 ! regulation of tube size GO:0035150 69 43 0,000 0,05475498 0,06391223 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,05475498 0,06388081 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,05475498 0,06384941 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,05475498 0,06381805 ! T cell differentiation GO:0030217 78 43 0,000 0,05475498 0,06378673 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,05475498 0,06375543 ! amino acid activation GO:0043038 61 43 0,000 0,05475498 0,06372416 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,05475498 0,06369292 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,05599339 0,06510158 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,05599339 0,0650697 ! cellular component disassembly GO:0022411 66 44 0,000 0,05599339 0,06503785 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,05599339 0,06500603 ! peptide metabolic process GO:0006518 64 44 0,000 0,05599339 0,06497424 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,05599339 0,06494248 ! inner ear development GO:0048839 66 44 0,000 0,05599339 0,06491076 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,05599339 0,06487906 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,05599339 0,0648474 ! chromatin remodeling GO:0006338 73 44 0,000 0,05599339 0,06481577 ! biopolymer methylation GO:0043414 67 44 0,000 0,05599339 0,06478416 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,05599339 0,06475259 ! JNK cascade GO:0007254 66 44 0,000 0,05599339 0,06472105 ! regulation of cell shape GO:0008360 83 44 0,000 0,05599339 0,06468954 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,05723025 0,06608632 ! positive regulation of binding GO:0051099 67 45 0,000 0,05723025 0,06605417 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,05723025 0,06602206 ! regulation of ion transport GO:0043269 60 45 0,000 0,05723025 0,06598998 ! glucose transport GO:0015758 60 45 0,000 0,05723025 0,06595793 ! neuromuscular process GO:0050905 89 45 0,000 0,05723025 0,06592591 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,05723025 0,06589393 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,05723025 0,06586197 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,05723025 0,06583004 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,05846555 0,06721838 ! regulation of translational initiation GO:0006446 70 46 0,000 0,05846555 0,06718583 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,05846555 0,06715331 ! regulation of action potential GO:0001508 80 46 0,000 0,05846555 0,06712082 ! hexose transport GO:0008645 62 46 0,000 0,05846555 0,06708837 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,05846555 0,06705594 ! excretion GO:0007588 72 46 0,000 0,05846555 0,06702355 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,05846555 0,06699118 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,05846555 0,06695885 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,05846555 0,06692655 ! positive regulation of defense response GO:0031349 70 47 0,000 0,05969929 0,06830589 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,05969929 0,06827297 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,05969929 0,06824008 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,05969929 0,06820723 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,05969929 0,0681744 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,05969929 0,06814161 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,06093147 0,06951461 ! viral infectious cycle GO:0019058 80 48 0,000 0,06093147 0,06948121 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,06093147 0,06944783 ! leukocyte migration GO:0050900 76 48 0,000 0,06093147 0,06941449 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,06093147 0,06938118 ! striated muscle contraction GO:0006941 78 48 0,000 0,06093147 0,06934791 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,06093147 0,06931466 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,06093147 0,06928145 ! tRNA processing GO:0008033 56 48 0,000 0,06093147 0,06924827 ! cell maturation GO:0048469 69 48 0,000 0,06093147 0,06921512 ! vesicle organization GO:0016050 87 48 0,000 0,06093147 0,069182 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,06093147 0,06914892 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,06216211 0,0705118 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,06216211 0,07047811 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,06216211 0,07044445 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,06216211 0,07041083 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,06216211 0,07037723 ! response to temperature stimulus GO:0009266 66 49 0,000 0,06216211 0,07034367 ! endocrine system development GO:0035270 86 49 0,000 0,06216211 0,07031014 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06216211 0,07027665 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,06216211 0,07024318 ! gastrulation GO:0007369 80 49 0,000 0,06216211 0,07020975 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,06216211 0,07017635 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,06216211 0,07014298 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,06216211 0,07010964 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,06216211 0,07007633 ! methylation GO:0032259 74 49 0,000 0,06216211 0,07004306 ! cell redox homeostasis GO:0045454 72 50 0,000 0,06339119 0,07139407 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,06339119 0,0713602 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,06339119 0,07132636 ! cellular polysaccharide metabolic process GO:0044264 70 50 0,000 0,06339119 0,07129256 ! histone modification GO:0016570 81 50 0,000 0,06339119 0,07125879 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,06339119 0,07122505 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,06339119 0,07119134 ! regulation of mast cell proliferation GO:0070666 80 50 0,000 0,06339119 0,07115766 ! RNA catabolic process GO:0006401 77 51 0,000 0,06461873 0,07250129 ! chloride transport GO:0006821 78 51 0,000 0,06461873 0,07246703 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,06461873 0,0724328 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,06461873 0,0723986 ! regulation of ossification GO:0030278 82 51 0,000 0,06461873 0,07236444 ! heart morphogenesis GO:0003007 71 51 0,000 0,06461873 0,0723303 ! RNA elongation GO:0006354 67 51 0,000 0,06461873 0,0722962 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,06461873 0,07226213 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,06584471 0,07359845 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,06584471 0,0735638 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,06584471 0,07352918 ! regulation of DNA replication GO:0006275 88 52 0,000 0,06584471 0,07349459 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,06584471 0,07346004 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,06584471 0,07342552 ! covalent chromatin modification GO:0016569 90 52 0,000 0,06584471 0,07339103 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,06584471 0,07335658 ! proton transport GO:0015992 78 52 0,000 0,06584471 0,07332215 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,06584471 0,07328776 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,06584471 0,0732534 ! transition metal ion transport GO:0000041 88 53 0,000 0,06706916 0,07458065 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,06706916 0,07454572 ! muscle fiber development GO:0048747 80 53 0,000 0,06706916 0,07451082 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,06706916 0,07447595 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,06706916 0,07444112 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,06706916 0,07440632 ! regulation of endocytosis GO:0030100 71 53 0,000 0,06706916 0,07437155 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,06706916 0,07433681 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,06706916 0,0743021 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,06706916 0,07426743 ! regulation of leukocyte proliferation GO:0070663 88 53 0,000 0,06706916 0,07423279 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! maintenance of location GO:0051235 94 53 0,000 0,06706916 0,07419819 ! hydrogen transport GO:0006818 81 54 0,000 0,06829206 0,07551587 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,06829206 0,07548069 ! regulation of mitosis GO:0007088 91 54 0,000 0,06829206 0,07544555 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,06829206 0,07541045 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,06829206 0,07537537 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,06829206 0,07534033 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,06829206 0,07530532 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,06829206 0,07527034 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,06829206 0,0752354 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,06829206 0,07520049 ! germ cell development GO:0007281 82 54 0,000 0,06829206 0,07516561 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,06829206 0,07513076 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,06829206 0,07509594 ! establishment of organelle localization GO:0051656 91 54 0,000 0,06829206 0,07506116 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,06951341 0,07636821 ! ear development GO:0043583 83 55 0,000 0,06951341 0,07633287 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,06951341 0,07629756 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,06951341 0,07626229 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,06951341 0,07622705 ! regulation of actin filament length GO:0030832 88 56 0,000 0,07073323 0,07752885 ! positive regulation of secretion GO:0051047 83 56 0,000 0,07073323 0,07749306 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,07073323 0,07745729 ! DNA catabolic process GO:0006308 71 56 0,000 0,07073323 0,07742157 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,07073323 0,07738587 ! adult behavior GO:0030534 90 56 0,000 0,07073323 0,07735021 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,07195151 0,07864622 ! mesoderm development GO:0007498 84 57 0,000 0,07195151 0,07861001 ! aging GO:0007568 91 57 0,000 0,07195151 0,07857383 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,07195151 0,07853769 ! single fertilization GO:0007338 67 57 0,000 0,07195151 0,07850158 ! regulation of cellular component size GO:0032535 90 58 0,000 0,07316826 0,0797924 ! lipid modification GO:0030258 82 58 0,000 0,07316826 0,07975575 ! positive regulation of growth GO:0045927 78 58 0,000 0,07316826 0,07971913 ! DNA damage response, signal transduction GO:0042770 105 58 0,000 0,07316826 0,07968255 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,07316826 0,079646 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,07316826 0,07960948 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,07438347 0,08089458 ! viral reproductive process GO:0022415 99 59 0,000 0,07438347 0,08085752 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07438347 0,0808205 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,07438347 0,08078351 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,07559714 0,08206406 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,07559714 0,08202653 ! kidney development GO:0001822 101 60 0,000 0,07559714 0,08198904 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,07559714 0,08195159 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,07680929 0,0832276 ! carbohydrate transport GO:0008643 83 61 0,000 0,07680929 0,08318962 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,07680929 0,08315167 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,07801991 0,08442374 ! amino acid transport GO:0006865 97 62 0,000 0,07801991 0,08438526 ! negative regulation of protein kinase activity GO:0006469 110 62 0,000 0,07801991 0,08434681 ! activation of MAPK activity GO:0000187 95 62 0,000 0,07801991 0,0843084 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,07801991 0,08427003 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,07801991 0,08423169 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,07801991 0,08419338 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,07801991 0,08415512 ! secondary metabolic process GO:0019748 95 62 0,000 0,07801991 0,08411688 ! gonad development GO:0008406 91 62 0,000 0,07801991 0,08407868 ! exocytosis GO:0006887 91 63 0,000 0,07922901 0,08534291 ! negative regulation of kinase activity GO:0033673 112 63 0,000 0,07922901 0,08530419 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,07922901 0,0852655 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,07922901 0,08522685 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,07922901 0,08518823 ! regulation of heart contraction GO:0008016 104 63 0,000 0,07922901 0,08514965 ! developmental maturation GO:0021700 90 63 0,000 0,07922901 0,08511111 ! actin filament organization GO:0007015 107 64 0,000 0,08043657 0,08636923 ! fertilization GO:0009566 79 64 0,000 0,08043657 0,08633016 ! viral reproduction GO:0016032 104 64 0,000 0,08043657 0,08629114 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,08043657 0,08625214 ! amine catabolic process GO:0009310 100 65 0,000 0,08164262 0,08750584 ! negative regulation of cell growth GO:0030308 123 65 0,000 0,08164262 0,08746634 ! camera-type eye development GO:0043010 103 65 0,000 0,08164262 0,08742687 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,08164262 0,08738743 ! regulation of lipase activity GO:0060191 117 65 0,000 0,08164262 0,08734803 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,08164262 0,08730867 ! organelle localization GO:0051640 105 65 0,000 0,08164262 0,08726934 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,08284714 0,08851701 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,08284714 0,08847717 ! sensory perception of smell GO:0007608 81 66 0,000 0,08284714 0,08843737 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,08284714 0,08839761 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,08284714 0,08835788 ! lung development GO:0030324 112 66 0,000 0,08284714 0,08831818 ! lymphocyte mediated immunity GO:0002449 95 66 0,000 0,08284714 0,08827852 ! B cell activation GO:0042113 119 66 0,000 0,08284714 0,0882389 ! negative regulation of transferase activity GO:0051348 117 66 0,000 0,08284714 0,08819932 ! protein oligomerization GO:0051259 109 66 0,000 0,08284714 0,08815976 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,08405015 0,08939982 ! negative regulation of cell size GO:0045792 125 67 0,000 0,08405015 0,08935977 ! neurotransmitter transport GO:0006836 92 67 0,000 0,08405015 0,08931975 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,08405015 0,08927977 ! appendage morphogenesis GO:0035107 103 67 0,000 0,08405015 0,08923982 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,08405015 0,08919991 ! extracellular matrix organization GO:0030198 117 67 0,000 0,08405015 0,08916004 ! meiosis GO:0007126 110 68 0,000 0,08525164 0,09039416 GO:0051327|M phase of meiotic cell cycle, ! regulation of caspase activity GO:0043281 104 68 0,000 0,08525164 0,09035379 ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,08525164 0,09031345 ! defense response to bacterium GO:0042742 79 68 0,000 0,08525164 0,09027315 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,08525164 0,09023289 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,08525164 0,09019266 ! activation of immune response GO:0002253 93 68 0,000 0,08525164 0,09015247 ! appendage development GO:0048736 108 69 0,000 0,08645161 0,0913807 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,08645161 0,09134001 ! urogenital system development GO:0001655 114 69 0,000 0,08645161 0,09129937 ! meiotic cell cycle GO:0051321 111 69 0,000 0,08645161 0,09125875 ! regulation of endopeptidase activity GO:0052548 106 70 0,000 0,08765007 0,09248271 ! adaptive immune response GO:0002250 102 70 0,000 0,08765007 0,09244161 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,08884702 0,09366236 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,08884702 0,09362077 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,08884702 0,09357922 ! response to drug GO:0042493 115 72 0,000 0,09004245 0,09479625 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,09004245 0,09475421 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,09004245 0,09471221 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,09004245 0,09467025 ! respiratory system development GO:0060541 123 72 0,000 0,09004245 0,09462832 ! rhythmic process GO:0048511 113 72 0,000 0,09004245 0,09458643 ! regulation of immune effector process GO:0002697 121 72 0,000 0,09004245 0,09454458 ! learning or memory GO:0007611 132 73 0,000 0,09123638 0,09575583 ! humoral immune response GO:0006959 93 73 0,000 0,09123638 0,0957135 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,09123638 0,09567121 ! acute inflammatory response GO:0002526 107 74 0,000 0,09242881 0,09687878 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,09242881 0,09683601 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,09242881 0,09679327 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,09242881 0,09675058 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,09242881 0,09670792 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,09242881 0,0966653 ! leukocyte mediated immunity GO:0002443 107 75 0,000 0,09361972 0,09786767 ! regulation of peptidase activity GO:0052547 113 75 0,000 0,09361972 0,09782457 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,09361972 0,09778152 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,09480914 0,09898024 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,09480914 0,09893671 ! negative regulation of transport GO:0051051 122 77 0,000 0,09599705 0,10013231 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,09599705 0,10008832 ! response to nutrient GO:0007584 114 77 0,000 0,09599705 0,10004436 ! regulation of blood pressure GO:0008217 119 78 0,000 0,09718347 0,10123634 ! muscle cell differentiation GO:0042692 117 78 0,000 0,09718347 0,10119191 ! mitochondrion organization GO:0007005 127 78 0,000 0,09718347 0,10114753 ! negative regulation of growth GO:0045926 140 78 0,000 0,09718347 0,10110319 ! amine transport GO:0015837 115 78 0,000 0,09718347 0,10105888 ! antigen processing and presentation GO:0019882 114 78 0,000 0,09718347 0,10101462 ! steroid biosynthetic process GO:0006694 111 79 0,000 0,09836839 0,10220148 ! regulation of adenylate cyclase activity GO:0045761 143 80 0,000 0,09955181 0,10338575 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,09955181 0,10334053 ! regulation of DNA binding GO:0051101 130 80 0,000 0,09955181 0,10329534 ! tube morphogenesis GO:0035239 140 80 0,000 0,09955181 0,10325019 ! eye development GO:0001654 130 80 0,000 0,09955181 0,10320509 ! protein ubiquitination GO:0016567 135 80 0,000 0,09955181 0,10316002 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,09955181 0,10311499 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,09955181 0,10307 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,09955181 0,10302505 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,09955181 0,10298014 ! blood coagulation GO:0007596 129 81 0,000 0,10073374 0,10415737 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,10073374 0,10411201 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,10073374 0,10406668 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,10073374 0,10402139 ! response to hypoxia GO:0001666 155 81 0,000 0,10073374 0,10397615 ! regulation of protein transport GO:0051223 123 81 0,000 0,10073374 0,10393094 GO:0070201|regulation of establishment of protein localization, ! regulation of cAMP biosynthetic process GO:0030817 148 82 0,000 0,10191418 0,10510315 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,10191418 0,10505749 ! regulation of cyclase activity GO:0031279 146 82 0,000 0,10191418 0,10501187 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,10309312 0,10618055 ! response to oxygen levels GO:0070482 160 83 0,000 0,10309312 0,10613448 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,10309312 0,10608846 ! regulation of lyase activity GO:0051339 147 83 0,000 0,10309312 0,10604247 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,10309312 0,10599653 ! positive regulation of lymphocyte activation GO:0051251 134 83 0,000 0,10309312 0,10595062 ! regulation of cAMP metabolic process GO:0030814 153 84 0,000 0,10427058 0,10711433 ! digestion GO:0007586 111 84 0,000 0,10427058 0,10706798 ! regulation of neurological system process GO:0031644 133 84 0,000 0,10427058 0,10702167 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,10427058 0,1069754 ! cellular respiration GO:0045333 119 85 0,000 0,10544656 0,10813512 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,10544656 0,10808841 ! T cell activation GO:0042110 154 85 0,000 0,10544656 0,10804174 ! sex differentiation GO:0007548 126 85 0,000 0,10544656 0,10799511 ! protein import into nucleus GO:0006606 145 85 0,000 0,10544656 0,10794852 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,10544656 0,10790197 ! carbohydrate biosynthetic process GO:0016051 111 86 0,000 0,10662104 0,10905678 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 0,000 0,10779405 0,11020908 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! hemostasis GO:0007599 138 87 0,000 0,10779405 0,11016162 ! regulation of defense response GO:0031347 135 87 0,000 0,10779405 0,1101142 ! tRNA metabolic process GO:0006399 110 87 0,000 0,10779405 0,11006682 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,10779405 0,11001948 ! gland development GO:0048732 170 87 0,000 0,10779405 0,10997218 ! vitamin metabolic process GO:0006766 117 87 0,000 0,10779405 0,10992492 ! forebrain development GO:0030900 151 87 0,000 0,10779405 0,1098777 ! regulation of membrane potential GO:0042391 144 88 0,000 0,10896557 0,11102418 ! ossification GO:0001503 150 89 0,000 0,11013562 0,11216817 GO:0060348|bone development, ! nucleosome assembly GO:0006334 113 89 0,000 0,11013562 0,11212004 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,11130419 0,11326108 ! microtubule cytoskeleton organization GO:0000226 133 90 0,000 0,11130419 0,11321253 ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 0,000 0,11130419 0,11316403 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,11130419 0,11311556 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,11130419 0,11306714 ! nuclear import GO:0051170 153 90 0,000 0,11130419 0,11301876 ! regulation of protein localization GO:0032880 141 90 0,000 0,11130419 0,11297042 ! positive regulation of cell activation GO:0050867 146 90 0,000 0,11130419 0,11292212 GO:0002696|positive regulation of leukocyte activation, ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,11247128 0,11405741 GO:0016054|organic acid catabolic process, ! protein localization in nucleus GO:0034504 161 92 0,000 0,1136369 0,11519024 ! sterol metabolic process GO:0016125 136 92 0,000 0,1136369 0,11514106 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,11480104 0,11627097 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,11480104 0,11622136 ! rRNA processing GO:0006364 124 93 0,000 0,11480104 0,1161718 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,11480104 0,11612228 ! regulation of nucleotide metabolic process GO:0006140 164 93 0,000 0,11480104 0,11607281 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,11480104 0,11602337 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,11480104 0,11597398 ! leukocyte differentiation GO:0002521 165 94 0,000 0,11596372 0,11709868 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,11596372 0,11704888 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,11596372 0,11699911 ! rRNA metabolic process GO:0016072 125 94 0,000 0,11596372 0,11694939 ! hormone metabolic process GO:0042445 135 94 0,000 0,11596372 0,11689971 ! protein processing GO:0016485 127 94 0,000 0,11596372 0,11685007 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,11712493 0,11797006 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,11712493 0,11792001 ! ATP metabolic process GO:0046034 150 96 0,000 0,11828467 0,11903712 ! nucleosome organization GO:0034728 126 96 0,000 0,11828467 0,11898665 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,11828467 0,11893624 ! female pregnancy GO:0007565 148 96 0,000 0,11828467 0,11888586 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,11944294 0,1199992 ! reproductive developmental process GO:0003006 149 97 0,000 0,11944294 0,11994842 ! response to virus GO:0009615 141 98 0,000 0,12059976 0,12105889 ! polysaccharide metabolic process GO:0005976 141 98 0,000 0,12059976 0,12100771 ! Wnt receptor signaling pathway GO:0016055 161 98 0,000 0,12059976 0,12095656 ! regulation of T cell activation GO:0050863 155 98 0,000 0,12059976 0,12090546 ! regulation of binding GO:0051098 164 99 0,000 0,12175511 0,12201219 ! electron transport chain GO:0022900 135 99 0,000 0,12175511 0,12196069 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,12175511 0,12190923 ! cell fate commitment GO:0045165 165 99 0,000 0,12175511 0,12185781 ! positive regulation of immune response GO:0050778 143 99 0,000 0,12175511 0,12180644 ! sulfur metabolic process GO:0006790 136 99 0,000 0,12175511 0,12175511