pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5717-7-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycolysis GO:0006096 53 44 5,000 1,743E-11 4,008E-08 ! glucose catabolic process GO:0006007 66 54 5,000 6,323E-11 7,272E-08 ! hexose catabolic process GO:0019320 82 64 5,000 1,82E-10 1,396E-07 ! monosaccharide catabolic process GO:0046365 91 71 5,000 3,457E-10 1,988E-07 ! alcohol catabolic process GO:0046164 104 80 5,000 7,199E-10 3,311E-07 ! carbohydrate catabolic process GO:0016052 121 93 5,000 1,806E-09 6,924E-07 ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 1,986E-08 6,525E-06 ! substrate-bound cell migration GO:0006929 10 9 2,000 1,662E-07 4,779E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 3,000 1,13E-06 2,889E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 3,000 1,207E-06 2,777E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 3,000 1,461E-06 3,055E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 3,000 1,461E-06 2,801E-04 ! positive regulation of ligase activity GO:0051351 99 69 3,000 1,859E-06 3,29E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 2,086E-06 3,427E-04 ! regulation of ligase activity GO:0051340 114 75 3,000 2,601E-06 3,988E-04 ! response to unfolded protein GO:0006986 99 76 3,000 2,743E-06 3,943E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 3,000 3,369E-06 4,559E-04 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 3,000 3,541E-06 4,525E-04 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 1,652E-05 2E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 1,652E-05 1,9E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,463E-05 3,793E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 3,463E-05 3,621E-03 ! cell projection assembly GO:0030031 76 53 2,000 4,464E-05 4,464E-03 ! phosphate transport GO:0006817 10 8 1,000 4,614E-05 4,422E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 4,614E-05 4,245E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 5,927E-05 5,243E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 5,927E-05 5,049E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 5,927E-05 4,869E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 2,000 6,482E-05 5,141E-03 ! negative regulation of ligase activity GO:0051352 91 61 2,000 6,811E-05 5,222E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of phosphatase activity GO:0010921 21 10 1,000 7,403E-05 5,493E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 7,403E-05 5,321E-03 ! axon guidance GO:0007411 99 66 2,000 8,623E-05 6,01E-03 ! detection of mechanical stimulus GO:0050982 15 11 1,000 9,041E-05 6,116E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 9,041E-05 5,941E-03 ! regulation of Ras GTPase activity GO:0032318 110 68 2,000 9,428E-05 6,023E-03 ! cartilage condensation GO:0001502 18 12 1,000 1,084E-04 6,739E-03 ! regulation of GTPase activity GO:0043087 129 80 2,000 1,53E-04 9,259E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 1,721E-04 0,01014667 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,965E-04 0,01129724 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 1,965E-04 0,0110217 ! negative regulation of translation GO:0017148 22 16 1,000 1,965E-04 0,01075928 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 2,501E-04 0,01337762 ! homophilic cell adhesion GO:0007156 149 100 2,000 2,96E-04 0,0154707 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,425E-04 0,01750329 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 3,764E-04 0,01881999 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 4,119E-04 0,02015767 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,119E-04 0,01973772 ! fat cell differentiation GO:0045444 37 24 1,000 4,49E-04 0,02107576 ! negative regulation of protein modification process GO:0031400 50 26 1,000 5,279E-04 0,02428223 ! response to mechanical stimulus GO:0009612 43 31 1,000 7,523E-04 0,03392506 ! RNA export from nucleus GO:0006405 44 33 1,000 8,528E-04 0,03772018 ! mRNA catabolic process GO:0006402 48 34 1,000 9,054E-04 0,03929007 ! regulation of Rab protein signal transduction GO:0032483 52 35 1,000 9,595E-04 0,0408669 GO:0032313|regulation of Rab GTPase activity, ! response to calcium ion GO:0051592 58 40 1,000 1,253E-03 0,05238947 ! JAK-STAT cascade GO:0007259 53 40 1,000 1,253E-03 0,05145395 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,447E-03 0,0583826 ! response to insulin stimulus GO:0032868 63 43 1,000 1,447E-03 0,05737601 ! detection of abiotic stimulus GO:0009582 58 44 1,000 1,515E-03 0,0590422 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,584E-03 0,06071 ! RNA catabolic process GO:0006401 64 45 1,000 1,584E-03 0,05971476 ! response to UV GO:0009411 75 46 1,000 1,654E-03 0,06137307 ! nuclear export GO:0051168 69 48 1,000 1,8E-03 0,06572091 ! cartilage development GO:0051216 70 49 1,000 1,875E-03 0,06739309 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 2,03E-03 0,07182751 ! regulation of protein catabolic process GO:0042176 77 51 1,000 2,03E-03 0,07073921 ! skeletal system morphogenesis GO:0048705 78 53 1,000 2,19E-03 0,07519249 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 2,273E-03 0,07687477 ! detection of external stimulus GO:0009581 66 54 1,000 2,273E-03 0,07576064 ! chromosome segregation GO:0007059 83 57 1,000 2,529E-03 0,08308971 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,529E-03 0,08191943 ! cell-matrix adhesion GO:0007160 114 61 1,000 2,89E-03 0,09233018 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 3,176E-03 0,1000812 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 3,176E-03 0,09872875 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 3,176E-03 0,09741237 ! regulation of actin filament-based process GO:0032970 99 66 1,000 3,374E-03 0,10211866 ! cell-substrate adhesion GO:0031589 121 66 1,000 3,374E-03 0,10079245 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 3,374E-03 0,09950024 ! inorganic anion transport GO:0015698 93 68 1,000 3,578E-03 0,1041657 ! response to metal ion GO:0010038 103 70 1,000 3,787E-03 0,10887596 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 3,787E-03 0,10753181 ! regulation of catabolic process GO:0009894 106 70 1,000 3,787E-03 0,10622045 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 4,002E-03 0,11089053 GO:0045937|positive regulation of phosphate metabolic process, ! response to inorganic substance GO:0010035 115 75 1,000 4,334E-03 0,11867406 ! positive regulation of protein modification process GO:0031401 107 78 1,000 4,679E-03 0,12661032 ! detection of stimulus GO:0051606 108 82 1,000 5,158E-03 0,13794868 ! regulation of cell adhesion GO:0030155 159 83 1,000 5,281E-03 0,13961867 ! Golgi vesicle transport GO:0048193 138 85 1,000 5,532E-03 0,14457517 ! cell cycle arrest GO:0007050 150 86 1,000 5,659E-03 0,14623768 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 5,659E-03 0,14461281 ! interphase GO:0051325 159 88 1,000 5,917E-03 0,14955466 ! establishment of RNA localization GO:0051236 128 88 1,000 5,917E-03 0,14792906 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 135 91 1,000 6,315E-03 0,1561715 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,562E-03 0,16055119 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 6,562E-03 0,15886117 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 6,562E-03 0,15720637 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 6,562E-03 0,15558569 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,562E-03 0,15399808 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 6,562E-03 0,15244254 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,562E-03 0,15091811 ! sleep GO:0030431 11 5 0,000 6,562E-03 0,14942388 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,562E-03 0,14795894 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,562E-03 0,14652244 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,562E-03 0,14511357 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 6,562E-03 0,14373154 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 6,562E-03 0,14237558 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 6,562E-03 0,14104497 ! tongue development GO:0043586 6 5 0,000 6,562E-03 0,139739 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 6,562E-03 0,13845699 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,562E-03 0,13719829 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 6,562E-03 0,13596227 ! cobalt ion transport GO:0006824 9 5 0,000 6,562E-03 0,13474832 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,562E-03 0,13355585 ! SMAD protein complex assembly GO:0007183 9 5 0,000 6,562E-03 0,13238431 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,562E-03 0,13123314 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,562E-03 0,13010182 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 6,562E-03 0,12898984 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,562E-03 0,12789671 ! embryonic camera-type eye development GO:0031076 8 5 0,000 6,562E-03 0,12682195 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 6,562E-03 0,1257651 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 6,562E-03 0,12472571 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,562E-03 0,12370337 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,562E-03 0,12269765 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,562E-03 0,12170816 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 6,562E-03 0,12073449 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 6,562E-03 0,11977628 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,562E-03 0,11883316 ! malate metabolic process GO:0006108 7 5 0,000 6,562E-03 0,11790478 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 6,562E-03 0,11699079 ! behavioral response to pain GO:0048266 7 5 0,000 6,562E-03 0,11609086 ! clathrin coat assembly GO:0048268 11 5 0,000 6,562E-03 0,11520467 ! phototransduction, visible light GO:0007603 6 5 0,000 6,562E-03 0,11433191 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,562E-03 0,11347227 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,562E-03 0,11262546 ! mating behavior GO:0007617 6 5 0,000 6,562E-03 0,1117912 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,562E-03 0,1109692 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,562E-03 0,11015921 ! rhythmic behavior GO:0007622 12 5 0,000 6,562E-03 0,10936095 ! copulation GO:0007620 7 5 0,000 6,562E-03 0,10857418 ! glial cell fate commitment GO:0021781 12 5 0,000 6,562E-03 0,10779865 ! protein maturation by protein folding GO:0022417 12 5 0,000 6,562E-03 0,10703412 ! embryonic hemopoiesis GO:0035162 10 5 0,000 6,562E-03 0,10628036 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,562E-03 0,10553714 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 6,562E-03 0,10480425 ! apoptotic cell clearance GO:0043277 13 5 0,000 6,562E-03 0,10408146 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,562E-03 0,10336857 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 6,562E-03 0,10266538 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,562E-03 0,1019717 ! response to protozoan GO:0001562 9 5 0,000 6,562E-03 0,10128733 ! positive regulation of glycolysis GO:0045821 11 5 0,000 6,562E-03 0,10061208 ! lymph vessel development GO:0001945 7 5 0,000 6,562E-03 0,09994577 ! endochondral ossification GO:0001958 12 5 0,000 6,562E-03 0,09928823 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,562E-03 0,09863929 ! parathyroid gland development GO:0060017 8 5 0,000 6,562E-03 0,09799878 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 6,562E-03 0,09736653 ! anagen GO:0042640 6 5 0,000 6,562E-03 0,09674238 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,562E-03 0,09612619 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,562E-03 0,09551779 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 6,562E-03 0,09491705 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 6,562E-03 0,09432382 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,562E-03 0,09373796 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 6,562E-03 0,09315933 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 6,562E-03 0,0925878 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 6,562E-03 0,09202324 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,562E-03 0,09146552 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,562E-03 0,09091453 ! cardiac muscle fiber development GO:0048739 7 5 0,000 6,562E-03 0,09037013 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 6,562E-03 0,08983221 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 6,562E-03 0,08930066 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,562E-03 0,08877536 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,562E-03 0,08825621 ! ovulation GO:0030728 6 5 0,000 6,562E-03 0,08774309 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,562E-03 0,0872359 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 6,562E-03 0,08673455 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,562E-03 0,08623892 ! response to pH GO:0009268 9 5 0,000 6,562E-03 0,08574893 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,562E-03 0,08526447 ! proline biosynthetic process GO:0006561 6 5 0,000 6,562E-03 0,08478546 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,562E-03 0,0843118 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 6,562E-03 0,0838434 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,562E-03 0,08338017 ! polyol catabolic process GO:0046174 7 5 0,000 6,562E-03 0,08292204 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,562E-03 0,08246892 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,562E-03 0,08202071 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,562E-03 0,08157736 ! sister chromatid cohesion GO:0007062 9 5 0,000 6,562E-03 0,08113877 ! nerve growth factor processing GO:0032455 7 5 0,000 6,562E-03 0,08070487 ! urea metabolic process GO:0019627 6 5 0,000 6,562E-03 0,08027559 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 6,562E-03 0,07985085 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,562E-03 0,07943059 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 6,562E-03 0,07901472 ! neutrophil activation GO:0042119 5 5 0,000 6,562E-03 0,07860318 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,562E-03 0,07819591 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,562E-03 0,07779284 ! response to food GO:0032094 5 5 0,000 6,562E-03 0,0773939 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,562E-03 0,07699904 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,562E-03 0,07660818 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,562E-03 0,07622127 ! forebrain neuron development GO:0021884 7 5 0,000 6,562E-03 0,07583825 ! melanosome organization GO:0032438 7 5 0,000 6,562E-03 0,07545906 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,562E-03 0,07508364 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 6,562E-03 0,07471194 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,562E-03 0,0743439 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 6,562E-03 0,07397947 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 6,562E-03 0,07361859 ! nucleoside transport GO:0015858 6 5 0,000 6,562E-03 0,07326122 ! nucleoside salvage GO:0043174 7 5 0,000 6,562E-03 0,0729073 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 6,562E-03 0,07255679 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,562E-03 0,07220962 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 6,562E-03 0,07186577 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,562E-03 0,07152517 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,562E-03 0,07118779 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,562E-03 0,07085357 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,562E-03 0,07052248 ! depyrimidination GO:0045008 8 5 0,000 6,562E-03 0,07019447 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 6,562E-03 0,0698695 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,562E-03 0,06954752 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 6,562E-03 0,06922849 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,562E-03 0,06891238 ! neuronal ion channel clustering GO:0045161 7 5 0,000 6,562E-03 0,06859914 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,562E-03 0,06828874 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 6,562E-03 0,06798113 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 6,562E-03 0,06767628 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,562E-03 0,06737416 ! monocyte differentiation GO:0030224 8 5 0,000 6,562E-03 0,06707472 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 6,562E-03 0,06677793 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 6,562E-03 0,06648375 ! centrosome duplication GO:0051298 5 5 0,000 6,562E-03 0,06619216 ! response to UV-C GO:0010225 6 5 0,000 6,562E-03 0,06590311 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,562E-03 0,06561657 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 6,562E-03 0,06533252 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,562E-03 0,06505091 ! regulation of dendrite development GO:0050773 12 5 0,000 6,562E-03 0,06477172 ! peptidyl-arginine modification GO:0018195 7 5 0,000 6,562E-03 0,06449492 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,562E-03 0,06422047 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 6,562E-03 0,06394835 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 6,562E-03 0,06367853 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 6,562E-03 0,06341097 ! regulation of dopamine secretion GO:0014059 12 5 0,000 6,562E-03 0,06314565 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,562E-03 0,06288255 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 6,562E-03 0,06262162 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,562E-03 0,06236286 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,562E-03 0,06210622 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 6,562E-03 0,06185169 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,562E-03 0,06159923 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 6,562E-03 0,06134883 ! neural tube patterning GO:0021532 6 5 0,000 6,562E-03 0,06110045 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,562E-03 0,06085408 ! histone demethylation GO:0016577 9 5 0,000 6,562E-03 0,06060968 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,562E-03 0,06036725 ! regulation of sterol transport GO:0032371 7 5 0,000 6,562E-03 0,06012674 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,562E-03 0,05988814 ! enteric nervous system development GO:0048484 8 5 0,000 6,562E-03 0,05965143 ! establishment of planar polarity GO:0001736 6 5 0,000 6,562E-03 0,05941658 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,562E-03 0,05918357 ! muscle cell proliferation GO:0033002 8 5 0,000 6,562E-03 0,05895239 ! transcription termination GO:0006353 8 5 0,000 6,562E-03 0,058723 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 6,562E-03 0,05849539 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 6,562E-03 0,05826954 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 6,562E-03 0,05804543 ! regulation of respiratory burst GO:0060263 8 5 0,000 6,562E-03 0,05782303 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,562E-03 0,05760233 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,562E-03 0,05738331 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,562E-03 0,05716595 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 6,562E-03 0,05695023 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,562E-03 0,05673613 ! apical protein localization GO:0045176 6 5 0,000 6,562E-03 0,05652364 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,562E-03 0,05631273 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,562E-03 0,05610339 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,562E-03 0,0558956 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,562E-03 0,05568934 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 6,562E-03 0,0554846 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 6,562E-03 0,05528136 ! triglyceride catabolic process GO:0019433 6 5 0,000 6,562E-03 0,0550796 ! glial cell migration GO:0008347 10 5 0,000 6,562E-03 0,05487931 ! determination of adult lifespan GO:0008340 8 5 0,000 6,562E-03 0,05468048 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,562E-03 0,05448307 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 6,562E-03 0,05428709 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,562E-03 0,05409251 ! somatic stem cell maintenance GO:0035019 13 5 0,000 6,562E-03 0,05389933 ! cerebellar cortex formation GO:0021697 6 5 0,000 6,562E-03 0,05370751 ! neural plate development GO:0001840 6 5 0,000 6,562E-03 0,05351706 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 6,562E-03 0,05332796 ! regulation of sensory perception GO:0051931 6 5 0,000 6,562E-03 0,05314018 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 6,562E-03 0,05295372 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 6,562E-03 0,05276857 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 6,562E-03 0,05258471 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 6,562E-03 0,05240212 ! sensory cilium assembly GO:0035058 6 5 0,000 6,562E-03 0,0522208 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 6,562E-03 0,05204073 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,562E-03 0,0518619 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 6,562E-03 0,05168429 ! spindle assembly GO:0051225 5 5 0,000 6,562E-03 0,05150789 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 6,562E-03 0,05133269 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 6,562E-03 0,05115868 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,562E-03 0,05098585 ! organ regeneration GO:0031100 7 5 0,000 6,562E-03 0,05081418 ! NAD biosynthetic process GO:0009435 7 5 0,000 6,562E-03 0,05064366 ! carnitine metabolic process GO:0009437 5 5 0,000 6,562E-03 0,05047429 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 6,562E-03 0,05030604 ! cellular anion homeostasis GO:0030002 6 5 0,000 6,562E-03 0,05013891 GO:0055081|anion homeostasis, ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 6,586E-03 0,05016172 ! in utero embryonic development GO:0001701 147 96 1,000 7,004E-03 0,05316459 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 7,004E-03 0,05298971 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 7,004E-03 0,05281597 ! response to light stimulus GO:0009416 153 96 1,000 7,004E-03 0,05264337 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 7,146E-03 0,05353389 ! calcium ion transport GO:0006816 167 99 1,000 7,433E-03 0,05550636 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 7,433E-03 0,05532673 ! regulation of translation GO:0006417 151 100 1,000 7,579E-03 0,05622892 ! divalent metal ion transport GO:0070838 171 100 1,000 7,579E-03 0,05604812 ! tRNA transcription GO:0009304 11 6 0,000 7,869E-03 0,05800893 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 7,869E-03 0,0578236 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 7,869E-03 0,05763944 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 7,869E-03 0,05745646 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,869E-03 0,05727464 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 7,869E-03 0,05709396 ! regulation of helicase activity GO:0051095 11 6 0,000 7,869E-03 0,05691442 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 7,869E-03 0,05673601 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 7,869E-03 0,05655871 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 7,869E-03 0,05638251 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 7,869E-03 0,05620741 ! positive regulation of axon extension GO:0045773 8 6 0,000 7,869E-03 0,05603339 ! prostate gland development GO:0030850 9 6 0,000 7,869E-03 0,05586045 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 7,869E-03 0,05568857 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,869E-03 0,05551775 ! forebrain neuron differentiation GO:0021879 9 6 0,000 7,869E-03 0,05534797 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 7,869E-03 0,05517922 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,869E-03 0,05501151 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,869E-03 0,05484481 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,869E-03 0,05467911 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,869E-03 0,05451441 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 7,869E-03 0,05435071 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 7,869E-03 0,05418798 ! neuron adhesion GO:0007158 9 6 0,000 7,869E-03 0,05402623 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 7,869E-03 0,05386543 ! establishment of tissue polarity GO:0007164 7 6 0,000 7,869E-03 0,0537056 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,869E-03 0,0535467 ! signal peptide processing GO:0006465 8 6 0,000 7,869E-03 0,05338875 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,869E-03 0,05323172 ! mRNA stabilization GO:0048255 15 6 0,000 7,869E-03 0,05307562 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 7,869E-03 0,05292043 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 7,869E-03 0,05276614 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 7,869E-03 0,05261275 ! opsonization GO:0008228 8 6 0,000 7,869E-03 0,05246025 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 7,869E-03 0,05230863 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 7,869E-03 0,05215788 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 7,869E-03 0,052008 ! protein amino acid dealkylation GO:0008214 11 6 0,000 7,869E-03 0,05185898 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 7,869E-03 0,05171082 ! photoreceptor cell development GO:0042461 10 6 0,000 7,869E-03 0,05156349 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 7,869E-03 0,051417 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 7,869E-03 0,05127135 ! mechanosensory behavior GO:0007638 8 6 0,000 7,869E-03 0,05112651 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 7,869E-03 0,05098249 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,869E-03 0,05083929 ! response to interferon-gamma GO:0034341 12 6 0,000 7,869E-03 0,05069688 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,869E-03 0,05055527 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 7,869E-03 0,05041444 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,869E-03 0,0502744 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 7,869E-03 0,05013514 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 7,869E-03 0,04999665 ! cGMP-mediated signaling GO:0019934 10 6 0,000 7,869E-03 0,04985891 ! activation of MAPKKK activity GO:0000185 10 6 0,000 7,869E-03 0,04972194 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 7,869E-03 0,04958571 ! thymic T cell selection GO:0045061 12 6 0,000 7,869E-03 0,04945023 ! protein lipoylation GO:0009249 10 6 0,000 7,869E-03 0,04931549 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 7,869E-03 0,04918148 ! pigment granule organization GO:0048753 11 6 0,000 7,869E-03 0,0490482 ! drug transport GO:0015893 6 6 0,000 7,869E-03 0,04891564 ! cysteine metabolic process GO:0006534 7 6 0,000 7,869E-03 0,04878379 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,869E-03 0,04865265 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 7,869E-03 0,04852221 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,869E-03 0,04839248 ! histidine metabolic process GO:0006547 6 6 0,000 7,869E-03 0,04826343 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 7,869E-03 0,04813507 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,869E-03 0,04800739 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 7,869E-03 0,04788039 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 7,869E-03 0,04775405 ! adenohypophysis development GO:0021984 10 6 0,000 7,869E-03 0,04762838 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 7,869E-03 0,04750337 ! hyperosmotic response GO:0006972 8 6 0,000 7,869E-03 0,04737902 ! microtubule nucleation GO:0007020 10 6 0,000 7,869E-03 0,04725532 ! ER overload response GO:0006983 7 6 0,000 7,869E-03 0,04713225 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 7,869E-03 0,04700983 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,869E-03 0,04688805 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,869E-03 0,04676689 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 7,869E-03 0,04664635 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,869E-03 0,04652644 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 7,869E-03 0,04640714 ! response to dietary excess GO:0002021 7 6 0,000 7,869E-03 0,04628845 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 7,869E-03 0,04617037 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,869E-03 0,04605289 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,869E-03 0,045936 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 7,869E-03 0,04581971 ! glycerol ether catabolic process GO:0044269 8 6 0,000 7,869E-03 0,045704 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 7,869E-03 0,04558888 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,869E-03 0,04547434 ! neuron apoptosis GO:0051402 8 6 0,000 7,869E-03 0,04536037 ! organic alcohol transport GO:0015850 9 6 0,000 7,869E-03 0,04524696 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 7,869E-03 0,04513413 ! T cell mediated immunity GO:0002456 12 6 0,000 7,869E-03 0,04502185 ! male sex determination GO:0030238 9 6 0,000 7,869E-03 0,04491014 ! carnitine transport GO:0015879 8 6 0,000 7,869E-03 0,04479897 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,869E-03 0,04468836 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 7,869E-03 0,04457829 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,869E-03 0,04446876 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 7,869E-03 0,04435977 ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,869E-03 0,04425131 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,869E-03 0,04414338 ! parturition GO:0007567 12 6 0,000 7,869E-03 0,04403597 ! negative regulation of translational initiation GO:0045947 7 6 0,000 7,869E-03 0,04392909 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,869E-03 0,04382273 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 7,869E-03 0,04371687 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 7,869E-03 0,04361153 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 7,869E-03 0,0435067 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,869E-03 0,04340236 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,869E-03 0,04329853 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 7,869E-03 0,04319519 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 7,869E-03 0,04309235 ! macrophage differentiation GO:0030225 10 6 0,000 7,869E-03 0,04298999 ! astrocyte development GO:0014002 14 6 0,000 7,869E-03 0,04288812 ! hyaluronan metabolic process GO:0030212 6 6 0,000 7,869E-03 0,04278673 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,869E-03 0,04268582 ! interaction with symbiont GO:0051702 8 6 0,000 7,869E-03 0,04258538 ! anterograde axon cargo transport GO:0008089 8 6 0,000 7,869E-03 0,04248541 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,869E-03 0,04238591 ! eating behavior GO:0042755 6 6 0,000 7,869E-03 0,04228688 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 7,869E-03 0,04218831 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 7,869E-03 0,0420902 ! response to copper ion GO:0046688 9 6 0,000 7,869E-03 0,04199254 ! DNA topological change GO:0006265 8 6 0,000 7,869E-03 0,04189534 ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,869E-03 0,04179858 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 7,869E-03 0,04170227 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,869E-03 0,0416064 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,869E-03 0,04151098 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,869E-03 0,04141599 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 7,869E-03 0,04132143 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 7,869E-03 0,0412273 ! nucleoside catabolic process GO:0009164 6 6 0,000 7,869E-03 0,0411336 ! gas homeostasis GO:0033483 11 6 0,000 7,869E-03 0,04104033 ! hair follicle maturation GO:0048820 7 6 0,000 7,869E-03 0,04094748 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 7,869E-03 0,04085505 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 7,869E-03 0,04076303 ! Schwann cell development GO:0014044 14 6 0,000 7,869E-03 0,04067143 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 7,869E-03 0,04058024 ! dendrite morphogenesis GO:0048813 9 6 0,000 7,869E-03 0,04048945 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,869E-03 0,04039908 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 7,869E-03 0,0403091 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,869E-03 0,04021952 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 7,869E-03 0,04013035 ! histone ubiquitination GO:0016574 7 6 0,000 7,869E-03 0,04004156 ! regulation of meiosis GO:0040020 10 6 0,000 7,869E-03 0,03995317 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 7,869E-03 0,03986517 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 7,869E-03 0,03977755 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 7,869E-03 0,03969032 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,869E-03 0,03960347 ! membrane to membrane docking GO:0022614 12 6 0,000 7,869E-03 0,039517 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 7,869E-03 0,03943091 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 7,869E-03 0,03934519 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 7,869E-03 0,03925984 ! receptor internalization GO:0031623 9 6 0,000 7,869E-03 0,03917486 ! neutrophil homeostasis GO:0001780 6 6 0,000 7,869E-03 0,03909025 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,869E-03 0,039006 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,869E-03 0,03892212 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 7,869E-03 0,0388386 ! protein deubiquitination GO:0016579 8 6 0,000 7,869E-03 0,03875543 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 7,869E-03 0,03867262 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 7,869E-03 0,03859016 ! peptidyl-histidine modification GO:0018202 9 6 0,000 7,869E-03 0,03850805 ! axonal fasciculation GO:0007413 9 6 0,000 7,869E-03 0,0384263 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 7,869E-03 0,03834488 ! thiamin metabolic process GO:0006772 6 6 0,000 7,869E-03 0,03826382 ! midbrain development GO:0030901 6 6 0,000 7,869E-03 0,03818309 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 7,869E-03 0,03810271 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,869E-03 0,03802266 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 7,869E-03 0,03794295 ! progesterone metabolic process GO:0042448 8 6 0,000 7,869E-03 0,03786357 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,869E-03 0,03778452 ! glycolipid catabolic process GO:0019377 13 6 0,000 7,869E-03 0,0377058 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 7,869E-03 0,03762741 ! positive regulation of glucose import GO:0046326 6 6 0,000 7,869E-03 0,03754935 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 7,869E-03 0,03747161 ! adult feeding behavior GO:0008343 6 6 0,000 7,869E-03 0,03739419 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 7,869E-03 0,03731708 ! blastocyst growth GO:0001832 15 6 0,000 7,869E-03 0,0372403 ! pigment granule transport GO:0051904 12 6 0,000 7,869E-03 0,03716383 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 7,869E-03 0,03708768 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 7,869E-03 0,03701183 ! catecholamine transport GO:0051937 7 6 0,000 7,869E-03 0,0369363 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,869E-03 0,03686107 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 7,869E-03 0,03678615 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 7,869E-03 0,03671153 ! negative regulation of B cell activation GO:0050869 9 6 0,000 7,869E-03 0,03663722 ! protein prenylation GO:0018342 10 6 0,000 7,869E-03 0,0365632 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,869E-03 0,03648949 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,869E-03 0,03641607 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 7,869E-03 0,03634294 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 7,869E-03 0,03627011 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,869E-03 0,03619757 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 9,175E-03 0,04211971 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 9,175E-03 0,04203581 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 9,175E-03 0,04195224 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 9,175E-03 0,041869 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 9,175E-03 0,04178609 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,175E-03 0,04170351 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 9,175E-03 0,04162125 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,175E-03 0,04153932 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 9,175E-03 0,04145771 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 9,175E-03 0,04137642 ! reproductive behavior GO:0019098 12 7 0,000 9,175E-03 0,04129545 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 9,175E-03 0,04121479 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 9,175E-03 0,04113445 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 9,175E-03 0,04105443 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 9,175E-03 0,04097471 ! oligopeptide transport GO:0006857 11 7 0,000 9,175E-03 0,0408953 ! protein amino acid sulfation GO:0006477 9 7 0,000 9,175E-03 0,0408162 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 9,175E-03 0,0407374 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 9,175E-03 0,04065891 ! RNA methylation GO:0001510 11 7 0,000 9,175E-03 0,04058072 ! pericardium development GO:0060039 8 7 0,000 9,175E-03 0,04050283 ! macrophage chemotaxis GO:0048246 10 7 0,000 9,175E-03 0,04042524 ! fibril organization GO:0043206 13 7 0,000 9,175E-03 0,04034794 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 9,175E-03 0,04027094 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,175E-03 0,04019424 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,175E-03 0,04011782 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 9,175E-03 0,0400417 ! lipoprotein transport GO:0042953 9 7 0,000 9,175E-03 0,03996586 ! cerebral cortex cell migration GO:0021795 11 7 0,000 9,175E-03 0,03989031 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,175E-03 0,03981505 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,175E-03 0,03974006 ! estrogen metabolic process GO:0008210 14 7 0,000 9,175E-03 0,03966537 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 9,175E-03 0,03959095 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 9,175E-03 0,03951681 ! chemosensory behavior GO:0007635 9 7 0,000 9,175E-03 0,03944294 ! microtubule bundle formation GO:0001578 8 7 0,000 9,175E-03 0,03936936 ! T-helper 1 type immune response GO:0042088 11 7 0,000 9,175E-03 0,03929604 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 9,175E-03 0,039223 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 9,175E-03 0,03915023 ! leukocyte degranulation GO:0043299 10 7 0,000 9,175E-03 0,03907773 ! bile acid and bile salt transport GO:0015721 9 7 0,000 9,175E-03 0,0390055 ! reflex GO:0060004 12 7 0,000 9,175E-03 0,03893353 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,175E-03 0,03886183 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,175E-03 0,03879039 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,175E-03 0,03871922 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 9,175E-03 0,0386483 ! glycerolipid catabolic process GO:0046503 9 7 0,000 9,175E-03 0,03857765 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,175E-03 0,03850725 ! spinal cord patterning GO:0021511 7 7 0,000 9,175E-03 0,03843711 ! hemoglobin metabolic process GO:0020027 10 7 0,000 9,175E-03 0,03836723 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 9,175E-03 0,03829759 ! adrenal gland development GO:0030325 17 7 0,000 9,175E-03 0,03822821 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 9,175E-03 0,03815909 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 9,175E-03 0,03809021 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 9,175E-03 0,03802158 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 9,175E-03 0,03795319 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 9,175E-03 0,03788505 ! endosome organization GO:0007032 10 7 0,000 9,175E-03 0,03781716 ! thyroid hormone generation GO:0006590 11 7 0,000 9,175E-03 0,03774951 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 9,175E-03 0,0376821 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 9,175E-03 0,03761493 ! regulation of pigmentation during development GO:0048070 15 7 0,000 9,175E-03 0,037548 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,175E-03 0,0374813 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 9,175E-03 0,03741485 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,175E-03 0,03734863 ! galactose metabolic process GO:0006012 10 7 0,000 9,175E-03 0,03728264 ! vesicle fusion GO:0006906 15 7 0,000 9,175E-03 0,03721689 ! intracellular pH reduction GO:0051452 10 7 0,000 9,175E-03 0,03715136 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 9,175E-03 0,03708607 ! organ growth GO:0035265 11 7 0,000 9,175E-03 0,03702101 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 9,175E-03 0,03695617 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 9,175E-03 0,03689156 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,175E-03 0,03682718 ! retinol metabolic process GO:0042572 9 7 0,000 9,175E-03 0,03676302 ! behavioral fear response GO:0001662 13 7 0,000 9,175E-03 0,03669909 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 9,175E-03 0,03663537 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 9,175E-03 0,03657188 ! rRNA modification GO:0000154 12 7 0,000 9,175E-03 0,03650861 ! protein heterooligomerization GO:0051291 10 7 0,000 9,175E-03 0,03644555 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,175E-03 0,03638271 ! response to UV-B GO:0010224 11 7 0,000 9,175E-03 0,03632009 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 9,175E-03 0,03625769 ! protein retention in ER lumen GO:0006621 12 7 0,000 9,175E-03 0,0361955 ! intermediate filament organization GO:0045109 11 7 0,000 9,175E-03 0,03613352 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 9,175E-03 0,03607175 ! cardiac muscle cell development GO:0055013 9 7 0,000 9,175E-03 0,0360102 ! fibrinolysis GO:0042730 9 7 0,000 9,175E-03 0,03594885 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 9,175E-03 0,03588771 ! regulation of circadian rhythm GO:0042752 11 7 0,000 9,175E-03 0,03582678 ! B cell lineage commitment GO:0002326 17 7 0,000 9,175E-03 0,03576606 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 9,175E-03 0,03570554 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 9,175E-03 0,03564523 ! response to tropane GO:0014073 13 7 0,000 9,175E-03 0,03558512 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 9,175E-03 0,03552521 ! melanosome localization GO:0032400 10 7 0,000 9,175E-03 0,0354655 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 9,175E-03 0,035406 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 9,175E-03 0,03534669 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 9,175E-03 0,03528758 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 9,175E-03 0,03522867 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 9,175E-03 0,03516996 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 9,175E-03 0,03511144 ! mast cell activation GO:0045576 9 7 0,000 9,175E-03 0,03505311 ! multicellular organismal aging GO:0010259 11 7 0,000 9,175E-03 0,03499498 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 9,175E-03 0,03493704 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 9,175E-03 0,0348793 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 9,175E-03 0,03482174 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 9,175E-03 0,03476437 ! establishment of nucleus localization GO:0040023 13 7 0,000 9,175E-03 0,03470719 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 9,175E-03 0,0346502 ! T cell lineage commitment GO:0002360 12 7 0,000 9,175E-03 0,0345934 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 9,175E-03 0,03453678 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 9,175E-03 0,03448035 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 9,175E-03 0,0344241 ! regulation of lipid transport GO:0032368 13 7 0,000 9,175E-03 0,03436804 ! response to tumor cell GO:0002347 12 7 0,000 9,175E-03 0,03431215 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 9,175E-03 0,03425645 ! neuroblast proliferation GO:0007405 13 7 0,000 9,175E-03 0,03420093 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 9,175E-03 0,03414559 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 9,175E-03 0,03409043 ! peptidyl-threonine modification GO:0018210 18 7 0,000 9,175E-03 0,03403544 ! diuresis GO:0030146 12 7 0,000 9,175E-03 0,03398064 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 9,175E-03 0,033926 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 9,175E-03 0,03387155 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,175E-03 0,03381727 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 9,175E-03 0,03376316 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,175E-03 0,03370922 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,175E-03 0,03365546 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,175E-03 0,03360187 ! regulation of synaptogenesis GO:0051963 10 7 0,000 9,175E-03 0,03354845 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 9,175E-03 0,0334952 ! dopamine biosynthetic process GO:0042416 15 7 0,000 9,175E-03 0,03344211 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 9,175E-03 0,0333892 ! lymph node development GO:0048535 9 7 0,000 9,175E-03 0,03333645 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 9,175E-03 0,03328387 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 9,175E-03 0,03323146 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,175E-03 0,03317921 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 9,175E-03 0,03312712 ! endosome to lysosome transport GO:0008333 10 7 0,000 9,175E-03 0,0330752 ! ATP catabolic process GO:0006200 10 7 0,000 9,175E-03 0,03302343 ! establishment of pigment granule localization GO:0051905 13 7 0,000 9,175E-03 0,03297184 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 9,175E-03 0,0329204 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 9,175E-03 0,03286912 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 9,175E-03 0,032818 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 9,175E-03 0,03276704 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 9,175E-03 0,03271624 ! muscle adaptation GO:0043500 12 7 0,000 9,175E-03 0,0326656 ! amino sugar catabolic process GO:0046348 9 7 0,000 9,175E-03 0,03261511 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 9,175E-03 0,03256478 ! retina homeostasis GO:0001895 9 7 0,000 9,175E-03 0,0325146 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 9,175E-03 0,03246458 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 9,175E-03 0,03241471 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 9,175E-03 0,03236499 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 9,175E-03 0,03231543 ! behavioral response to nicotine GO:0035095 11 7 0,000 9,175E-03 0,03226602 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,175E-03 0,03221675 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,175E-03 0,03216764 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01047886 0,03668399 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01047886 0,03662824 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01047886 0,03657266 ! axon extension GO:0048675 11 8 0,000 0,01047886 0,03651725 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01047886 0,036462 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01047886 0,03640692 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01047886 0,03635201 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01047886 0,03629726 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01047886 0,03624268 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01047886 0,03618826 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01047886 0,03613401 ! N-glycan processing GO:0006491 12 8 0,000 0,01047886 0,03607991 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01047886 0,03602598 ! UTP metabolic process GO:0046051 8 8 0,000 0,01047886 0,03597221 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01047886 0,0359186 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01047886 0,03586515 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01047886 0,03581186 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01047886 0,03575873 ! succinate metabolic process GO:0006105 14 8 0,000 0,01047886 0,03570575 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01047886 0,03565293 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01047886 0,03560027 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01047886 0,03554776 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01047886 0,03549541 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01047886 0,03544321 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01047886 0,03539116 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01047886 0,03533927 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01047886 0,03528753 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01047886 0,03523594 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01047886 0,0351845 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01047886 0,03513321 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01047886 0,03508207 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01047886 0,03503108 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01047886 0,03498024 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01047886 0,03492954 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01047886 0,03487899 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01047886 0,03482859 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01047886 0,03477833 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01047886 0,03472822 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01047886 0,03467825 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01047886 0,03462842 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01047886 0,03457874 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01047886 0,0345292 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01047886 0,0344798 ! melanin metabolic process GO:0006582 12 8 0,000 0,01047886 0,03443055 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01047886 0,03438143 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01047886 0,03433245 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01047886 0,03428362 ! macrophage activation GO:0042116 12 8 0,000 0,01047886 0,03423492 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01047886 0,03418636 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01047886 0,03413794 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01047886 0,03408965 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01047886 0,0340415 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01047886 0,03399349 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01047886 0,03394561 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01047886 0,03389787 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01047886 0,03385026 ! ruffle organization GO:0031529 11 8 0,000 0,01047886 0,03380278 ! osteoblast development GO:0002076 13 8 0,000 0,01047886 0,03375544 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01047886 0,03370823 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01047886 0,03366115 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01047886 0,0336142 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01047886 0,03356739 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01047886 0,0335207 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01047886 0,03347414 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01047886 0,03342771 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01047886 0,03338142 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01047886 0,03333525 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01047886 0,0332892 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01047886 0,03324329 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01047886 0,0331975 ! segment specification GO:0007379 10 8 0,000 0,01047886 0,03315183 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01047886 0,03310629 ! cellular extravasation GO:0045123 11 8 0,000 0,01047886 0,03306088 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01047886 0,03301559 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01047886 0,03297043 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01047886 0,03292539 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01047886 0,03288047 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01047886 0,03283567 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01047886 0,032791 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01047886 0,03274644 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01047886 0,03270201 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01047886 0,0326577 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01047886 0,03261351 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01047886 0,03256944 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01047886 0,03252548 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01047886 0,03248165 ! icosanoid secretion GO:0032309 12 8 0,000 0,01047886 0,03243793 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01047886 0,03239433 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01047886 0,03235085 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01047886 0,03230748 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01047886 0,03226423 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01047886 0,0322211 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01047886 0,03217808 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01047886 0,03213518 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01047886 0,03209239 ! sterol catabolic process GO:0016127 9 8 0,000 0,01047886 0,03204971 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01047886 0,03200715 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01047886 0,0319647 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01047886 0,03192236 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01047886 0,03188014 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01047886 0,03183802 ! prophase GO:0051324 11 8 0,000 0,01047886 0,03179602 ! S phase GO:0051320 8 8 0,000 0,01047886 0,03175413 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01047886 0,03171235 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01047886 0,03167067 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01047886 0,03162911 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01047886 0,03158766 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01047886 0,03154631 ! hormone catabolic process GO:0042447 13 8 0,000 0,01047886 0,03150508 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01047886 0,03146395 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01047886 0,03142292 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01047886 0,03138201 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01047886 0,0313412 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01047886 0,0313005 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01047886 0,0312599 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01047886 0,03121941 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01047886 0,03117902 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01047886 0,03113874 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01047886 0,03109856 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01047886 0,03105848 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01047886 0,03101851 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01047886 0,03097864 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01047886 0,03093887 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01047886 0,03089921 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01047886 0,03085964 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01178131 0,03465091 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01178131 0,03460666 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01178131 0,03456252 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01178131 0,03451849 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01178131 0,03447457 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01178131 0,03443077 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01178131 0,03438707 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01178131 0,03434349 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01178131 0,03430002 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01178131 0,03425666 ! GTP metabolic process GO:0046039 9 9 0,000 0,01178131 0,0342134 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01178131 0,03417026 ! social behavior GO:0035176 14 9 0,000 0,01178131 0,03412722 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01178131 0,03408429 ! artery development GO:0060840 19 9 0,000 0,01178131 0,03404148 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01178131 0,03399876 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01178131 0,03395616 ! response to pain GO:0048265 16 9 0,000 0,01178131 0,03391366 ! protein complex disassembly GO:0043241 17 9 0,000 0,01178131 0,03387127 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01178131 0,03382898 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01178131 0,0337868 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01178131 0,03374473 ! lung alveolus development GO:0048286 17 9 0,000 0,01178131 0,03370275 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01178131 0,03366089 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01178131 0,03361912 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01178131 0,03357746 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01178131 0,03353591 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01178131 0,03349446 ! protein targeting to ER GO:0045047 19 9 0,000 0,01178131 0,0334531 ! T cell selection GO:0045058 18 9 0,000 0,01178131 0,03341185 ! endoderm development GO:0007492 12 9 0,000 0,01178131 0,03337071 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01178131 0,03332966 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01178131 0,03328872 ! arginine catabolic process GO:0006527 10 9 0,000 0,01178131 0,03324787 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01178131 0,03320713 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01178131 0,03316648 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01178131 0,03312593 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01178131 0,03308549 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01178131 0,03304514 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01178131 0,03300489 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01178131 0,03296474 ! mannose metabolic process GO:0006013 9 9 0,000 0,01178131 0,03292468 ! receptor clustering GO:0043113 15 9 0,000 0,01178131 0,03288473 ! epithelial cell development GO:0002064 10 9 0,000 0,01178131 0,03284487 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01178131 0,0328051 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01178131 0,03276543 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01178131 0,03272586 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01178131 0,03268639 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01178131 0,03264701 ! motor axon guidance GO:0008045 14 9 0,000 0,01178131 0,03260772 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01178131 0,03256853 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01178131 0,03252943 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01178131 0,03249042 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01178131 0,03245151 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01178131 0,0324127 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01178131 0,03237397 ! DNA ligation GO:0006266 14 9 0,000 0,01178131 0,03233534 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01178131 0,0322968 ! response to amine stimulus GO:0014075 13 9 0,000 0,01178131 0,03225835 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01178131 0,03221999 ! erythrocyte development GO:0048821 11 9 0,000 0,01178131 0,03218173 ! renal water homeostasis GO:0003091 14 9 0,000 0,01178131 0,03214355 ! postreplication repair GO:0006301 11 9 0,000 0,01178131 0,03210547 ! mRNA cleavage GO:0006379 13 9 0,000 0,01178131 0,03206747 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01178131 0,03202957 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01178131 0,03199175 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01178131 0,03195403 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01178131 0,03191639 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01178131 0,03187884 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01178131 0,03184138 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01178131 0,03180401 ! acid secretion GO:0046717 14 9 0,000 0,01178131 0,03176672 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01178131 0,03172952 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01178131 0,03169241 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01178131 0,03165539 ! purine base metabolic process GO:0006144 18 9 0,000 0,01178131 0,03161845 ! oocyte differentiation GO:0009994 12 9 0,000 0,01178131 0,0315816 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01178131 0,03154484 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01178131 0,03150816 ! spleen development GO:0048536 15 9 0,000 0,01178131 0,03147156 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01178131 0,03143505 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01178131 0,03139863 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01178131 0,03136228 ! detection of calcium ion GO:0005513 13 9 0,000 0,01178131 0,03132603 ! blastocyst formation GO:0001825 12 9 0,000 0,01178131 0,03128985 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01178131 0,03125376 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01178131 0,03121776 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01178131 0,03118183 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01178131 0,03114599 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01178131 0,03111023 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01178131 0,03107456 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01178131 0,03103896 ! prepulse inhibition GO:0060134 14 9 0,000 0,01178131 0,03100345 ! embryonic placenta development GO:0001892 12 9 0,000 0,01178131 0,03096802 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01178131 0,03093266 ! insulin secretion GO:0030073 17 9 0,000 0,01178131 0,03089739 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01178131 0,0308622 ! response to nicotine GO:0035094 16 9 0,000 0,01178131 0,03082709 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01178131 0,03079206 ! nucleus localization GO:0051647 15 9 0,000 0,01178131 0,03075711 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01178131 0,03072224 ! localization within membrane GO:0051668 15 9 0,000 0,01178131 0,03068745 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01308212 0,03403719 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01308212 0,03399873 ! neuron fate specification GO:0048665 11 10 0,000 0,01308212 0,03396035 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01308212 0,03392207 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01308212 0,03388387 ! thyroid gland development GO:0030878 19 10 0,000 0,01308212 0,03384575 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01308212 0,03380772 ! synapsis GO:0007129 13 10 0,000 0,01308212 0,03376978 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01308212 0,03373192 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01308212 0,03369415 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01308212 0,03365646 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01308212 0,03361885 ! sulfate transport GO:0008272 12 10 0,000 0,01308212 0,03358133 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01308212 0,0335439 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01308212 0,03350654 ! androgen metabolic process GO:0008209 13 10 0,000 0,01308212 0,03346927 ! phospholipid efflux GO:0033700 16 10 0,000 0,01308212 0,03343208 ! hippocampus development GO:0021766 19 10 0,000 0,01308212 0,03339498 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01308212 0,03335795 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01308212 0,03332101 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01308212 0,03328415 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01308212 0,03324737 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01308212 0,03321068 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01308212 0,03317406 ! pathogenesis GO:0009405 13 10 0,000 0,01308212 0,03313753 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01308212 0,03310107 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01308212 0,0330647 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01308212 0,0330284 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01308212 0,03299219 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01308212 0,03295605 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01308212 0,03291999 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01308212 0,03288402 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01308212 0,03284812 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01308212 0,03281229 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01308212 0,03277655 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01308212 0,03274089 ! response to X-ray GO:0010165 16 10 0,000 0,01308212 0,0327053 ! B cell proliferation GO:0042100 14 10 0,000 0,01308212 0,03266979 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01308212 0,03263435 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01308212 0,032599 ! forebrain cell migration GO:0021885 17 10 0,000 0,01308212 0,03256372 ! lipid digestion GO:0044241 15 10 0,000 0,01308212 0,03252851 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01308212 0,03249338 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01308212 0,03245833 ! UV protection GO:0009650 14 10 0,000 0,01308212 0,03242336 ! entry into host cell GO:0030260 20 10 0,000 0,01308212 0,03238845 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01308212 0,03235363 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01308212 0,03231888 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01308212 0,0322842 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01308212 0,0322496 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01308212 0,03221507 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01308212 0,03218061 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01308212 0,03214623 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01308212 0,03211193 ! regulation of organ growth GO:0046620 11 10 0,000 0,01308212 0,03207769 ! response to dsRNA GO:0043331 18 10 0,000 0,01308212 0,03204353 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01308212 0,03200944 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01308212 0,03197542 ! embryonic axis specification GO:0000578 12 10 0,000 0,01308212 0,03194148 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01308212 0,03190761 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01308212 0,03187381 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01308212 0,03184008 ! cranial nerve development GO:0021545 12 10 0,000 0,01308212 0,03180642 ! fucose catabolic process GO:0019317 16 10 0,000 0,01308212 0,03177283 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01308212 0,03173932 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01308212 0,03170587 ! protein sumoylation GO:0016925 12 10 0,000 0,01308212 0,0316725 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01308212 0,03163919 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01308212 0,03160596 ! zymogen activation GO:0031638 14 10 0,000 0,01308212 0,0315728 ! salivary gland development GO:0007431 22 10 0,000 0,01308212 0,0315397 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01308212 0,03150667 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01308212 0,03147372 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01308212 0,03144083 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01308212 0,03140801 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01308212 0,03137526 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01308212 0,03134258 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01308212 0,03130996 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01308212 0,03127742 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01308212 0,03124494 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01308212 0,03121253 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01308212 0,03118018 ! detection of bacterium GO:0016045 10 10 0,000 0,01308212 0,0311479 ! embryonic gut development GO:0048566 11 10 0,000 0,01308212 0,03111569 ! activation of innate immune response GO:0002218 10 10 0,000 0,01308212 0,03108355 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01308212 0,03105147 ! developmental induction GO:0031128 13 10 0,000 0,01308212 0,03101946 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01308212 0,03098751 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01308212 0,03095563 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01308212 0,03092382 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01308212 0,03089207 ! rRNA transcription GO:0009303 17 11 0,000 0,01438129 0,03392509 ! respiratory burst GO:0045730 14 11 0,000 0,01438129 0,03389033 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01438129 0,03385565 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01438129 0,03382103 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01438129 0,03378648 ! virus-host interaction GO:0019048 17 11 0,000 0,01438129 0,03375201 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01438129 0,0337176 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01438129 0,03368327 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01438129 0,033649 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01438129 0,0336148 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01438129 0,03358068 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01438129 0,03354662 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,01438129 0,03351263 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01438129 0,03347871 ! T cell proliferation GO:0042098 20 11 0,000 0,01438129 0,03344486 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01438129 0,03341108 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01438129 0,03337736 ! bone resorption GO:0045453 16 11 0,000 0,01438129 0,03334372 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01438129 0,03331014 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01438129 0,03327663 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01438129 0,03324318 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01438129 0,03320981 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01438129 0,0331765 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01438129 0,03314325 ! syncytium formation GO:0006949 15 11 0,000 0,01438129 0,03311008 ! plasma membrane organization GO:0007009 18 11 0,000 0,01438129 0,03307697 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01438129 0,03304392 ! focal adhesion formation GO:0048041 24 11 0,000 0,01438129 0,03301094 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01438129 0,03297803 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01438129 0,03294519 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01438129 0,0329124 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01438129 0,03287969 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01438129 0,03284704 ! adult heart development GO:0007512 11 11 0,000 0,01438129 0,03281445 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01438129 0,03278193 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01438129 0,03274947 ! temperature homeostasis GO:0001659 16 11 0,000 0,01438129 0,03271708 ! L-glutamate transport GO:0015813 16 11 0,000 0,01438129 0,03268475 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01438129 0,03265248 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01438129 0,03262028 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01438129 0,03258814 ! stem cell development GO:0048864 29 11 0,000 0,01438129 0,03255607 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01438129 0,03252406 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01438129 0,03249211 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01438129 0,03246022 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01438129 0,0324284 ! vasoconstriction GO:0042310 15 11 0,000 0,01438129 0,03239664 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01438129 0,03236494 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01438129 0,0323333 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01438129 0,03230173 ! ribosome assembly GO:0042255 13 11 0,000 0,01438129 0,03227021 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01438129 0,03223876 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01438129 0,03220737 ! chromatin silencing GO:0006342 19 11 0,000 0,01438129 0,03217604 ! nucleosome positioning GO:0016584 13 11 0,000 0,01438129 0,03214477 ! T cell homeostasis GO:0043029 20 11 0,000 0,01438129 0,03211356 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01438129 0,03208241 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01438129 0,03205132 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01438129 0,0320203 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01438129 0,03198933 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01438129 0,03195842 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01438129 0,03192757 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01438129 0,03189679 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01438129 0,03186606 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01438129 0,03183539 ! male genitalia development GO:0030539 13 11 0,000 0,01438129 0,03180478 ! cholesterol efflux GO:0033344 19 11 0,000 0,01438129 0,03177422 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01438129 0,03174373 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01438129 0,0317133 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01438129 0,03168292 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01438129 0,0316526 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01438129 0,03162234 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01438129 0,03159214 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01438129 0,03156199 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01438129 0,0315319 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01438129 0,03150187 ! lysogeny GO:0030069 18 11 0,000 0,01438129 0,0314719 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01438129 0,03144198 ! acrosome reaction GO:0007340 13 11 0,000 0,01438129 0,03141212 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01438129 0,03138232 ! lactation GO:0007595 20 12 0,000 0,01567882 0,03418132 ! reproductive cellular process GO:0048610 14 12 0,000 0,01567882 0,03414896 ! tRNA modification GO:0006400 14 12 0,000 0,01567882 0,03411665 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01567882 0,0340844 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01567882 0,03405222 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01567882 0,03402009 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01567882 0,03398803 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01567882 0,03395602 ! non-recombinational repair GO:0000726 19 12 0,000 0,01567882 0,03392408 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01567882 0,0338922 ! peroxisomal transport GO:0043574 21 12 0,000 0,01567882 0,03386037 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01567882 0,03382861 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01567882 0,0337969 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01567882 0,03376526 ! heart looping GO:0001947 15 12 0,000 0,01567882 0,03373367 ! palate development GO:0060021 15 12 0,000 0,01567882 0,03370215 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01567882 0,03367068 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01567882 0,03363927 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01567882 0,03360792 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01567882 0,03357663 ! arginine metabolic process GO:0006525 13 12 0,000 0,01567882 0,03354539 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01567882 0,03351422 ! methionine metabolic process GO:0006555 13 12 0,000 0,01567882 0,0334831 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01567882 0,03345204 ! Golgi organization GO:0007030 18 12 0,000 0,01567882 0,03342104 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01567882 0,03339009 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01567882 0,0333592 ! monoamine transport GO:0015844 13 12 0,000 0,01567882 0,03332837 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01567882 0,0332976 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01567882 0,03326688 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01567882 0,03323622 ! L-amino acid transport GO:0015807 20 12 0,000 0,01567882 0,03320561 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01567882 0,03317507 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01567882 0,03314457 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01567882 0,03311414 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01567882 0,03308376 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01567882 0,03305343 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01567882 0,03302317 ! cerebellum development GO:0021549 13 12 0,000 0,01567882 0,03299295 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01567882 0,03296279 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01567882 0,03293269 ! histone acetylation GO:0016573 23 12 0,000 0,01567882 0,03290264 ! histone methylation GO:0016571 15 12 0,000 0,01567882 0,03287265 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01567882 0,03284271 ! gland morphogenesis GO:0022612 23 12 0,000 0,01567882 0,03281283 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01567882 0,032783 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01567882 0,03275322 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01567882 0,0327235 ! response to gamma radiation GO:0010332 20 12 0,000 0,01567882 0,03269383 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01567882 0,03266422 ! intestinal absorption GO:0050892 19 12 0,000 0,01567882 0,03263466 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01567882 0,03260515 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01567882 0,0325757 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01567882 0,0325463 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01567882 0,03251695 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01567882 0,03248765 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01567882 0,03245841 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01567882 0,03242922 ! microspike assembly GO:0030035 23 12 0,000 0,01567882 0,03240009 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01567882 0,032371 ! response to cold GO:0009409 14 12 0,000 0,01567882 0,03234197 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01697473 0,03498375 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01697473 0,03495243 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01697473 0,03492117 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01697473 0,03488996 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01697473 0,03485881 ! water transport GO:0006833 17 13 0,000 0,01697473 0,03482772 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01697473 0,03479667 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01697473 0,03476569 ! lipid localization GO:0010876 24 13 0,000 0,01697473 0,03473476 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01697473 0,03470388 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01697473 0,03467306 ! organelle fusion GO:0048284 28 13 0,000 0,01697473 0,0346423 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01697473 0,03461159 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01697473 0,03458093 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01697473 0,03455033 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01697473 0,03451978 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01697473 0,03448928 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01697473 0,03445884 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01697473 0,03442846 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01697473 0,03439812 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01697473 0,03436784 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01697473 0,03433762 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01697473 0,03430744 ! NAD metabolic process GO:0019674 21 13 0,000 0,01697473 0,03427732 ! exocrine system development GO:0035272 27 13 0,000 0,01697473 0,03424725 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01697473 0,03421724 ! bone mineralization GO:0030282 15 13 0,000 0,01697473 0,03418728 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01697473 0,03415737 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01697473 0,03412751 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01697473 0,0340977 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01697473 0,03406795 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01697473 0,03403825 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01697473 0,0340086 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01697473 0,033979 ! genitalia development GO:0048806 15 13 0,000 0,01697473 0,03394945 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01697473 0,03391996 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01697473 0,03389051 ! cellular pigmentation GO:0033059 24 13 0,000 0,01697473 0,03386112 ! tissue regeneration GO:0042246 21 13 0,000 0,01697473 0,03383178 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01697473 0,03380248 ! cofactor transport GO:0051181 19 13 0,000 0,01697473 0,03377324 ! NADP metabolic process GO:0006739 18 13 0,000 0,01697473 0,03374405 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01697473 0,03371491 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01697473 0,03368582 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01697473 0,03365678 ! gas transport GO:0015669 18 13 0,000 0,01697473 0,03362779 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01697473 0,03359885 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01697473 0,03356996 ! regulation of axon extension GO:0030516 23 13 0,000 0,01697473 0,03354112 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01697473 0,03351233 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01697473 0,03348359 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01697473 0,0334549 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01697473 0,03342626 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01697473 0,03339766 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01697473 0,03336912 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01826899 0,03588274 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01826899 0,03585212 ! superoxide anion generation GO:0042554 18 14 0,000 0,01826899 0,03582156 ! neuron maturation GO:0042551 21 14 0,000 0,01826899 0,03579105 ! regulation of S phase GO:0033261 18 14 0,000 0,01826899 0,03576058 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01826899 0,03573018 ! myotube differentiation GO:0014902 21 14 0,000 0,01826899 0,03569982 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01826899 0,03566951 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01826899 0,03563926 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01826899 0,03560906 ! inositol metabolic process GO:0006020 20 14 0,000 0,01826899 0,03557891 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01826899 0,0355488 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01826899 0,03551875 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01826899 0,03548876 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01826899 0,03545881 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01826899 0,03542891 ! response to cAMP GO:0051591 19 14 0,000 0,01826899 0,03539906 ! limbic system development GO:0021761 25 14 0,000 0,01826899 0,03536927 ! startle response GO:0001964 21 14 0,000 0,01826899 0,03533952 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01826899 0,03530982 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01826899 0,03528017 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01826899 0,03525058 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01826899 0,03522103 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01826899 0,03519153 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01826899 0,03516208 ! glycine metabolic process GO:0006544 22 14 0,000 0,01826899 0,03513268 ! pituitary gland development GO:0021983 23 14 0,000 0,01826899 0,03510333 ! cellular response to starvation GO:0009267 21 14 0,000 0,01826899 0,03507403 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01826899 0,03504478 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01826899 0,03501557 ! regulation of heart rate GO:0002027 23 14 0,000 0,01826899 0,03498642 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01826899 0,03495731 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01826899 0,03492825 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01826899 0,03489924 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01826899 0,03487028 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01826899 0,03484137 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01826899 0,0348125 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01826899 0,03478368 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01826899 0,03475491 ! axon cargo transport GO:0008088 27 14 0,000 0,01826899 0,03472619 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01826899 0,03469751 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01826899 0,03466888 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01826899 0,0346403 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01826899 0,03461177 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01826899 0,03458328 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01826899 0,03455484 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01826899 0,03452645 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01826899 0,0344981 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01826899 0,0344698 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01826899 0,03444155 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01826899 0,03441334 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01826899 0,03438518 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01826899 0,03435706 ! muscle maintenance GO:0046716 19 14 0,000 0,01826899 0,03432899 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01826899 0,03430097 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01826899 0,03427299 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01826899 0,03424506 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01826899 0,03421717 ! cell killing GO:0001906 20 14 0,000 0,01826899 0,03418933 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01826899 0,03416153 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01826899 0,03413378 ! cilium assembly GO:0042384 20 14 0,000 0,01826899 0,03410608 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01826899 0,03407842 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01956163 0,03646009 ! metencephalon development GO:0022037 19 15 0,000 0,01956163 0,03643057 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01956163 0,0364011 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01956163 0,03637167 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01956163 0,03634229 ! skin development GO:0043588 25 15 0,000 0,01956163 0,03631296 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01956163 0,03628367 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01956163 0,03625444 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01956163 0,03622525 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01956163 0,0361961 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01956163 0,03616701 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01956163 0,03613796 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01956163 0,03610895 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01956163 0,03608 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01956163 0,03605109 ! adult walking behavior GO:0007628 25 15 0,000 0,01956163 0,03602222 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01956163 0,0359934 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01956163 0,03596463 ! myoblast differentiation GO:0045445 27 15 0,000 0,01956163 0,03593591 ! centrosome cycle GO:0007098 16 15 0,000 0,01956163 0,03590723 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01956163 0,03587859 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01956163 0,03585 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01956163 0,03582146 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01956163 0,03579296 ! cerebral cortex development GO:0021987 29 15 0,000 0,01956163 0,03576451 ! response to osmotic stress GO:0006970 22 15 0,000 0,01956163 0,0357361 ! vesicle coating GO:0006901 25 15 0,000 0,01956163 0,03570774 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01956163 0,03567943 ! DNA integration GO:0015074 22 15 0,000 0,01956163 0,03565115 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01956163 0,03562293 ! peptide secretion GO:0002790 27 15 0,000 0,01956163 0,03559474 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01956163 0,03556661 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01956163 0,03553851 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01956163 0,03551046 ! neuron recognition GO:0008038 22 15 0,000 0,01956163 0,03548246 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01956163 0,0354545 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01956163 0,03542658 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01956163 0,03539871 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01956163 0,03537088 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01956163 0,03534309 ! biomineral formation GO:0031214 18 15 0,000 0,01956163 0,03531535 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01956163 0,03528765 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01956163 0,03526 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01956163 0,03523239 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01956163 0,03520482 ! organic cation transport GO:0015695 19 15 0,000 0,01956163 0,03517729 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01956163 0,03514981 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01956163 0,03512237 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01956163 0,03509497 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01956163 0,03506762 ! defense response to virus GO:0051607 27 15 0,000 0,01956163 0,03504031 ! peptide hormone processing GO:0016486 19 15 0,000 0,01956163 0,03501304 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01956163 0,03498581 ! protein secretion GO:0009306 27 16 0,000 0,02085264 0,0372658 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02085264 0,03723686 ! hormone secretion GO:0046879 25 16 0,000 0,02085264 0,03720798 ! bone remodeling GO:0046849 24 16 0,000 0,02085264 0,03717913 ! endothelial cell migration GO:0043542 22 16 0,000 0,02085264 0,03715033 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02085264 0,03712158 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02085264 0,03709287 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02085264 0,0370642 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02085264 0,03703558 ! glial cell development GO:0021782 24 16 0,000 0,02085264 0,03700701 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02085264 0,03697847 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02085264 0,03694998 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02085264 0,03692154 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02085264 0,03689314 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02085264 0,03686478 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02085264 0,03683647 ! fructose metabolic process GO:0006000 20 16 0,000 0,02085264 0,0368082 ! regulation of protein binding GO:0043393 27 16 0,000 0,02085264 0,03677997 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02085264 0,03675179 ! protein export from nucleus GO:0006611 24 16 0,000 0,02085264 0,03672364 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02085264 0,03669555 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02085264 0,03666749 ! DNA replication initiation GO:0006270 25 16 0,000 0,02085264 0,03663948 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02085264 0,03661151 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02085264 0,03658359 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02085264 0,0365557 ! diencephalon development GO:0021536 25 16 0,000 0,02085264 0,03652786 ! oogenesis GO:0048477 23 16 0,000 0,02085264 0,03650006 ! neural crest cell migration GO:0001755 24 16 0,000 0,02085264 0,0364723 ! G1 phase GO:0051318 27 16 0,000 0,02085264 0,03644459 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02085264 0,03641692 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02085264 0,03638929 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02085264 0,0363617 ! steroid catabolic process GO:0006706 22 16 0,000 0,02085264 0,03633415 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02085264 0,03630665 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02085264 0,03627918 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02085264 0,03625176 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02085264 0,03622438 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02085264 0,03619704 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02085264 0,03616974 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02085264 0,03614249 ! nerve development GO:0021675 18 16 0,000 0,02085264 0,03611527 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02085264 0,0360881 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02085264 0,03606096 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02214203 0,03826196 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02214203 0,03823323 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02214203 0,03820455 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02214203 0,03817591 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02214203 0,03814731 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02214203 0,03811876 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02214203 0,03809025 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02214203 0,03806178 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02214203 0,03803336 ! signal complex assembly GO:0007172 29 17 0,000 0,02214203 0,03800497 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02214203 0,03797663 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02214203 0,03794833 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02214203 0,03792008 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02214203 0,03789186 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02214203 0,03786369 ! memory GO:0007613 25 17 0,000 0,02214203 0,03783556 ! keratinization GO:0031424 17 17 0,000 0,02214203 0,03780747 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02214203 0,03777942 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02214203 0,03775142 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02214203 0,03772346 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02214203 0,03769553 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02214203 0,03766765 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02214203 0,03763981 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02214203 0,03761201 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02214203 0,03758425 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02214203 0,03755654 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02214203 0,03752886 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02214203 0,03750123 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02214203 0,03747363 ! membrane budding GO:0006900 29 17 0,000 0,02214203 0,03744608 ! heme metabolic process GO:0042168 27 17 0,000 0,02214203 0,03741856 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02214203 0,03739109 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02214203 0,03736366 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02214203 0,03733626 ! body fluid secretion GO:0007589 27 17 0,000 0,02214203 0,03730891 ! stem cell differentiation GO:0048863 36 17 0,000 0,02214203 0,0372816 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02214203 0,03725433 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02214203 0,03722709 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02214203 0,0371999 ! sensory perception of pain GO:0019233 23 17 0,000 0,02214203 0,03717275 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02214203 0,03714563 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02214203 0,03711856 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02214203 0,03709153 ! synaptogenesis GO:0007416 24 17 0,000 0,02214203 0,03706453 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02214203 0,03703757 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02214203 0,03701066 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02214203 0,03698378 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02214203 0,03695694 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02214203 0,03693014 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02214203 0,03690338 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02214203 0,03687666 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02214203 0,03684997 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02214203 0,03682333 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02214203 0,03679672 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02342979 0,03890867 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02342979 0,0388806 ! positive regulation of translation GO:0045727 28 18 0,000 0,02342979 0,03885257 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02342979 0,03882458 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02342979 0,03879663 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02342979 0,03876871 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02342979 0,03874084 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02342979 0,03871301 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02342979 0,03868522 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02342979 0,03865747 ! axis specification GO:0009798 26 18 0,000 0,02342979 0,03862976 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02342979 0,03860209 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02342979 0,03857445 ! pancreas development GO:0031016 26 18 0,000 0,02342979 0,03854686 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02342979 0,03851931 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02342979 0,0384918 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02342979 0,03846432 ! response to retinoic acid GO:0032526 25 18 0,000 0,02342979 0,03843689 ! pigmentation during development GO:0048066 31 18 0,000 0,02342979 0,03840949 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02342979 0,03838213 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02342979 0,03835481 ! fucose metabolic process GO:0006004 26 18 0,000 0,02342979 0,03832753 ! response to fungus GO:0009620 19 18 0,000 0,02342979 0,03830029 ! peptide cross-linking GO:0018149 31 18 0,000 0,02342979 0,03827309 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02342979 0,03824593 ! heart process GO:0003015 27 18 0,000 0,02342979 0,0382188 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02342979 0,03819172 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02342979 0,03816467 ! visual learning GO:0008542 35 18 0,000 0,02342979 0,03813766 ! somitogenesis GO:0001756 24 18 0,000 0,02342979 0,03811069 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02342979 0,03808375 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02342979 0,03805686 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02342979 0,03803 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02342979 0,03800318 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02342979 0,0379764 ! vitamin transport GO:0051180 24 18 0,000 0,02342979 0,03794966 ! hormone transport GO:0009914 27 18 0,000 0,02342979 0,03792295 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02342979 0,03789628 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02342979 0,03786965 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02342979 0,03784306 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02342979 0,0378165 ! cell-cell recognition GO:0009988 20 18 0,000 0,02342979 0,03778998 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02342979 0,0377635 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02342979 0,03773705 ! regulation of glucose import GO:0046324 21 18 0,000 0,02342979 0,03771065 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02342979 0,03768428 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02342979 0,03765794 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02342979 0,03763164 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02342979 0,03760538 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02471593 0,039642 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02471593 0,03961438 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,02471593 0,03958679 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02471593 0,03955924 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02471593 0,03953173 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02471593 0,03950426 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02471593 0,03947683 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02471593 0,03944943 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02471593 0,03942207 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02471593 0,03939475 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02471593 0,03936747 ! regeneration GO:0031099 32 19 0,000 0,02471593 0,03934023 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02471593 0,03931302 ! response to alkaloid GO:0043279 32 19 0,000 0,02471593 0,03928585 ! sensory perception of taste GO:0050909 23 19 0,000 0,02471593 0,03925872 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02471593 0,03923163 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02471593 0,03920457 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02471593 0,03917755 ! peroxisome organization GO:0007031 29 19 0,000 0,02471593 0,03915057 ! digestive system process GO:0022600 30 19 0,000 0,02471593 0,03912363 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02471593 0,03909672 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02471593 0,03906985 ! response to vitamin A GO:0033189 26 19 0,000 0,02471593 0,03904302 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02471593 0,03901622 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02471593 0,03898946 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02471593 0,03896274 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02471593 0,03893605 ! response to starvation GO:0042594 30 19 0,000 0,02471593 0,0389094 ! sex determination GO:0007530 29 19 0,000 0,02471593 0,03888278 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02471593 0,03885621 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02471593 0,03882967 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02471593 0,03880316 ! cytolysis GO:0019835 20 19 0,000 0,02471593 0,03877669 ! renal system process GO:0003014 35 19 0,000 0,02471593 0,03875026 ! vasodilation GO:0042311 33 19 0,000 0,02471593 0,03872386 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02471593 0,0386975 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02471593 0,03867118 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02471593 0,03864489 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02471593 0,03861864 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02471593 0,03859242 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02471593 0,03856624 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02471593 0,03854009 ! sarcomere organization GO:0045214 23 19 0,000 0,02471593 0,03851398 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02471593 0,0384879 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02471593 0,03846186 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02471593 0,03843586 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02471593 0,03840989 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02471593 0,03838395 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02471593 0,03835805 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02471593 0,03833219 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02471593 0,03830635 ! protein stabilization GO:0050821 26 19 0,000 0,02471593 0,03828056 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02600044 0,04024295 ! iron ion transport GO:0006826 37 20 0,000 0,02600044 0,04021589 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02600044 0,04018886 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02600044 0,04016187 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02600044 0,04013491 ! response to vitamin GO:0033273 29 20 0,000 0,02600044 0,040108 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02600044 0,04008111 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02600044 0,04005427 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02600044 0,04002746 ! spinal cord development GO:0021510 31 20 0,000 0,02600044 0,04000068 ! response to ethanol GO:0045471 37 20 0,000 0,02600044 0,03997394 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02600044 0,03994724 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,02600044 0,03992058 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02600044 0,03989394 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02600044 0,03986735 ! chromosome condensation GO:0030261 31 20 0,000 0,02600044 0,03984079 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02600044 0,03981426 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02600044 0,03978777 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02600044 0,03976132 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02600044 0,0397349 ! pallium development GO:0021543 38 20 0,000 0,02600044 0,03970851 ! DNA modification GO:0006304 28 20 0,000 0,02600044 0,03968216 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,02600044 0,03965585 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,02600044 0,03962957 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02600044 0,03960333 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02600044 0,03957712 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02600044 0,03955094 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,02600044 0,0395248 ! collagen catabolic process GO:0030574 25 20 0,000 0,02600044 0,03949869 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02600044 0,03947262 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02600044 0,03944658 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02600044 0,03942058 ! alditol metabolic process GO:0019400 24 20 0,000 0,02600044 0,03939461 ! actin filament-based movement GO:0030048 34 20 0,000 0,02600044 0,03936868 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02728334 0,04128401 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02728334 0,04125686 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02728334 0,04122976 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02728334 0,04120269 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,02728334 0,04117565 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02728334 0,04114865 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02728334 0,04112168 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02728334 0,04109475 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02728334 0,04106786 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02728334 0,041041 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02728334 0,04101418 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02728334 0,04098739 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02728334 0,04096063 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02728334 0,04093391 ! vesicle docking GO:0048278 27 21 0,000 0,02728334 0,04090723 ! phototransduction GO:0007602 25 21 0,000 0,02728334 0,04088058 ! dendrite development GO:0016358 35 21 0,000 0,02728334 0,04085397 ! visual behavior GO:0007632 39 21 0,000 0,02728334 0,04082738 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02728334 0,04080084 ! ovarian follicle development GO:0001541 30 21 0,000 0,02728334 0,04077433 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02728334 0,04074785 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02728334 0,04072141 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02728334 0,040695 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02728334 0,04066863 ! cell aging GO:0007569 32 21 0,000 0,02728334 0,04064229 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02728334 0,04061598 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02728334 0,04058971 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02728334 0,04056347 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02728334 0,04053727 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02728334 0,0405111 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02728334 0,04048496 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02728334 0,04045886 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02728334 0,04043279 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02728334 0,04040675 ! fatty acid transport GO:0015908 30 21 0,000 0,02728334 0,04038075 ! immunoglobulin production GO:0002377 33 21 0,000 0,02728334 0,04035478 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02728334 0,04032885 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02728334 0,04030295 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02728334 0,04027708 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02728334 0,04025124 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,02728334 0,04022544 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02728334 0,04019967 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02728334 0,04017394 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02728334 0,04014823 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02728334 0,04012256 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02728334 0,04009693 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02728334 0,04007132 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02728334 0,04004575 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02728334 0,04002021 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02728334 0,0399947 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02728334 0,03996923 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02856463 0,04181963 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02856463 0,04179303 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,02856463 0,04176646 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02856463 0,04173992 ! viral genome replication GO:0019079 29 22 0,000 0,02856463 0,04171342 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02856463 0,04168696 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02856463 0,04166052 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02856463 0,04163412 ! molting cycle process GO:0022404 40 22 0,000 0,02856463 0,04160775 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02856463 0,04158142 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02856463 0,04155512 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02856463 0,04152885 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02856463 0,04150262 ! vasculogenesis GO:0001570 33 22 0,000 0,02856463 0,04147641 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02856463 0,04145025 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02856463 0,04142411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02856463 0,04139801 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02856463 0,04137194 ! lysosome organization GO:0007040 37 22 0,000 0,02856463 0,0413459 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02856463 0,0413199 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02856463 0,04129393 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02856463 0,04126799 ! regulation of behavior GO:0050795 38 22 0,000 0,02856463 0,04124208 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02856463 0,04121621 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02856463 0,04119037 ! membrane depolarization GO:0051899 35 22 0,000 0,02856463 0,04116456 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02856463 0,04113879 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02856463 0,04111304 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02856463 0,04108733 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02856463 0,04106165 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02856463 0,041036 ! blastocyst development GO:0001824 37 22 0,000 0,02856463 0,04101039 ! neural tube closure GO:0001843 33 22 0,000 0,02856463 0,0409848 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02856463 0,04095925 ! protein tetramerization GO:0051262 39 22 0,000 0,02856463 0,04093373 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,0298443 0,0427409 ! neuron fate commitment GO:0048663 32 23 0,000 0,0298443 0,0427143 ! embryonic pattern specification GO:0009880 31 23 0,000 0,0298443 0,04268774 ! myelination GO:0042552 35 23 0,000 0,0298443 0,04266121 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,0298443 0,04263471 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,0298443 0,04260824 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,0298443 0,04258181 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,0298443 0,04255541 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,0298443 0,04252905 ! vesicle targeting GO:0006903 32 23 0,000 0,0298443 0,04250271 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,0298443 0,04247641 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,0298443 0,04245014 ! osteoblast differentiation GO:0001649 40 23 0,000 0,0298443 0,04242391 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,0298443 0,0423977 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,0298443 0,04237153 ! interaction with host GO:0051701 37 23 0,000 0,0298443 0,04234539 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,0298443 0,04231928 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,0298443 0,04229321 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,0298443 0,04226717 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,0298443 0,04224116 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,0298443 0,04221518 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,0298443 0,04218923 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,0298443 0,04216332 ! cell fate determination GO:0001709 45 23 0,000 0,0298443 0,04213743 ! pentose metabolic process GO:0019321 31 23 0,000 0,0298443 0,04211158 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,0298443 0,04208576 ! spermatid development GO:0007286 33 23 0,000 0,0298443 0,04205997 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,0298443 0,04203422 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,0298443 0,04200849 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,0298443 0,0419828 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,0298443 0,04195714 ! telomere organization GO:0032200 32 23 0,000 0,0298443 0,04193151 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,0298443 0,04190591 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,0298443 0,04188034 ! regulation of amine transport GO:0051952 38 23 0,000 0,0298443 0,0418548 ! liver development GO:0001889 40 23 0,000 0,0298443 0,0418293 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03112235 0,04359404 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03112235 0,0435675 ! initiation of viral infection GO:0019059 42 24 0,000 0,03112235 0,043541 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03112235 0,04351453 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03112235 0,0434881 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03112235 0,04346169 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03112235 0,04343532 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,03112235 0,04340898 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03112235 0,04338267 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03112235 0,04335639 ! sperm motility GO:0030317 27 24 0,000 0,03112235 0,04333015 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03112235 0,04330394 ! vacuole organization GO:0007033 39 24 0,000 0,03112235 0,04327776 ! receptor metabolic process GO:0043112 37 24 0,000 0,03112235 0,04325161 ! neural crest cell development GO:0014032 39 24 0,000 0,03112235 0,04322549 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03112235 0,0431994 ! primary neural tube formation GO:0014020 35 24 0,000 0,03112235 0,04317335 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03112235 0,04314732 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03112235 0,04312133 ! base-excision repair GO:0006284 31 24 0,000 0,03112235 0,04309537 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03112235 0,04306944 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03112235 0,04304354 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03112235 0,04301767 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03112235 0,04299184 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03112235 0,04296603 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03112235 0,04294026 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03112235 0,04291451 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,0323988 0,04464783 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,0323988 0,0446211 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,0323988 0,04459439 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,0323988 0,04456772 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,0323988 0,04454108 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,0323988 0,04451448 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,0323988 0,0444879 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,0323988 0,04446136 ! peptide transport GO:0015833 43 25 0,000 0,0323988 0,04443484 ! male gonad development GO:0008584 33 25 0,000 0,0323988 0,04440836 ! iron ion homeostasis GO:0055072 39 25 0,000 0,0323988 0,04438191 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,0323988 0,0443555 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,0323988 0,04432911 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,0323988 0,04430275 ! phospholipid transport GO:0015914 35 25 0,000 0,0323988 0,04427643 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,0323988 0,04425014 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,0323988 0,04422388 ! detection of light stimulus GO:0009583 30 25 0,000 0,0323988 0,04419765 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,0323988 0,04417145 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,0323988 0,04414528 ! leukocyte proliferation GO:0070661 39 25 0,000 0,0323988 0,04411914 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,0323988 0,04409304 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03367363 0,04580092 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03367363 0,04577385 ! translational initiation GO:0006413 43 26 0,000 0,03367363 0,04574681 ! regulation of pH GO:0006885 36 26 0,000 0,03367363 0,04571981 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03367363 0,04569284 ! circadian rhythm GO:0007623 42 26 0,000 0,03367363 0,04566589 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03367363 0,04563899 ! post-embryonic development GO:0009791 42 26 0,000 0,03367363 0,04561211 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03367363 0,04558526 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03367363 0,04555845 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03367363 0,04553166 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03367363 0,04550491 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03367363 0,04547819 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03367363 0,0454515 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03367363 0,04542484 ! regulation of coagulation GO:0050818 39 26 0,000 0,03367363 0,04539822 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,03494686 0,04708716 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,03494686 0,04705959 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,03494686 0,04703206 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,03494686 0,04700455 ! membrane docking GO:0022406 39 27 0,000 0,03494686 0,04697708 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,03494686 0,04694964 ! catechol metabolic process GO:0009712 43 27 0,000 0,03494686 0,04692223 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,03494686 0,04689486 ! acute-phase response GO:0006953 42 27 0,000 0,03494686 0,04686751 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,03494686 0,0468402 ! myofibril assembly GO:0030239 36 27 0,000 0,03494686 0,04681292 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,03494686 0,04678567 ! response to ionizing radiation GO:0010212 47 27 0,000 0,03494686 0,04675846 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,03494686 0,04673127 ! natural killer cell activation GO:0030101 35 27 0,000 0,03494686 0,04670412 ! lipid oxidation GO:0034440 38 27 0,000 0,03494686 0,046677 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,03494686 0,04664991 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,03494686 0,04662285 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,03494686 0,04659582 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,03494686 0,04656882 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,03494686 0,04654186 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,03494686 0,04651492 ! gene silencing GO:0016458 41 27 0,000 0,03494686 0,04648802 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03621849 0,04815175 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03621849 0,04812393 ! phenol metabolic process GO:0018958 44 28 0,000 0,03621849 0,04809615 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03621849 0,04806839 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03621849 0,04804067 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03621849 0,04801298 ! cell junction assembly GO:0034329 56 28 0,000 0,03621849 0,04798533 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03621849 0,0479577 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03621849 0,04793011 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03621849 0,04790254 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03621849 0,04787501 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03621849 0,04784752 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03621849 0,04782005 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03621849 0,04779261 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03621849 0,04776521 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03621849 0,04773784 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03621849 0,0477105 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03621849 0,04768319 ! mesoderm formation GO:0001707 46 28 0,000 0,03621849 0,04765591 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03621849 0,04762866 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03621849 0,04760144 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03621849 0,04757426 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03621849 0,0475471 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03621849 0,04751998 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03621849 0,04749289 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03621849 0,04746583 ! neural tube formation GO:0001841 41 28 0,000 0,03621849 0,0474388 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03621849 0,0474118 ! placenta development GO:0001890 37 28 0,000 0,03621849 0,04738483 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03621849 0,04735789 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03748851 0,04899067 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03748851 0,04896285 ! ovulation cycle process GO:0022602 41 29 0,000 0,03748851 0,04893506 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03748851 0,0489073 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03748851 0,04887958 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03748851 0,04885189 ! mismatch repair GO:0006298 34 29 0,000 0,03748851 0,04882422 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03748851 0,04879659 ! muscle cell development GO:0055001 38 29 0,000 0,03748851 0,04876899 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03748851 0,04874142 ! telencephalon development GO:0021537 52 29 0,000 0,03748851 0,04871389 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03748851 0,04868638 ! eye morphogenesis GO:0048592 51 29 0,000 0,03748851 0,0486589 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03748851 0,04863146 ! tissue homeostasis GO:0001894 42 29 0,000 0,03748851 0,04860405 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03875693 0,05022025 ! collagen metabolic process GO:0032963 40 30 0,000 0,03875693 0,05019197 ! organic anion transport GO:0015711 51 30 0,000 0,03875693 0,05016373 ! cholesterol transport GO:0030301 46 30 0,000 0,03875693 0,05013552 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03875693 0,05010733 ! spliceosome assembly GO:0000245 49 30 0,000 0,03875693 0,05007918 ! spindle organization GO:0007051 37 30 0,000 0,03875693 0,05005107 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03875693 0,05002298 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03875693 0,04999492 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03875693 0,0499669 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03875693 0,04993891 ! ovulation cycle GO:0042698 43 30 0,000 0,03875693 0,04991094 ! hindbrain development GO:0030902 45 30 0,000 0,03875693 0,04988301 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03875693 0,04985512 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03875693 0,04982725 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03875693 0,04979941 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03875693 0,04977161 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,03875693 0,04974383 ! response to heat GO:0009408 41 30 0,000 0,03875693 0,04971609 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03875693 0,04968838 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03875693 0,0496607 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,04002376 0,05125537 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04002376 0,05122684 ! mammary gland development GO:0030879 57 31 0,000 0,04002376 0,05119835 ! glial cell differentiation GO:0010001 55 31 0,000 0,04002376 0,05116989 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04002376 0,05114147 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04002376 0,05111307 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04002376 0,05108471 ! odontogenesis GO:0042476 50 31 0,000 0,04002376 0,05105637 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04002376 0,05102807 ! segmentation GO:0035282 41 31 0,000 0,04002376 0,0509998 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04002376 0,05097156 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04002376 0,05094335 ! metanephros development GO:0001656 58 31 0,000 0,04002376 0,05091518 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04002376 0,05088703 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04002376 0,05085892 ! cell fate specification GO:0001708 37 31 0,000 0,04002376 0,05083083 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04002376 0,05080278 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04002376 0,05077476 ! RNA modification GO:0009451 40 31 0,000 0,04002376 0,05074677 ! regulation of muscle development GO:0048634 48 32 0,000 0,04128898 0,05232213 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04128898 0,05229331 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04128898 0,05226453 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,04128898 0,05223579 ! meiosis I GO:0007127 52 32 0,000 0,04128898 0,05220707 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,04128898 0,05217838 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,04128898 0,05214973 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04128898 0,05212111 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04128898 0,05209252 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04128898 0,05206396 ! regulation of protein stability GO:0031647 48 32 0,000 0,04128898 0,05203543 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04128898 0,05200693 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04128898 0,05197847 ! cytokine production GO:0001816 44 32 0,000 0,04128898 0,05195003 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04128898 0,05192163 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04128898 0,05189326 ! vesicle localization GO:0051648 47 32 0,000 0,04128898 0,05186491 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04255261 0,05342304 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04255261 0,05339389 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04255261 0,05336478 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04255261 0,0533357 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04255261 0,05330665 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04255261 0,05327763 ! ear morphogenesis GO:0042471 42 33 0,000 0,04255261 0,05324864 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04255261 0,05321969 ! cell junction organization GO:0034330 63 33 0,000 0,04255261 0,05319077 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04255261 0,05316187 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04255261 0,05313301 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04255261 0,05310418 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04255261 0,05307538 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04255261 0,05304662 ! female gonad development GO:0008585 49 33 0,000 0,04255261 0,05301788 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04255261 0,05298918 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04255261 0,0529605 ! lipid homeostasis GO:0055088 55 33 0,000 0,04255261 0,05293186 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04255261 0,05290325 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04255261 0,05287467 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04255261 0,05284612 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04255261 0,0528176 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04255261 0,05278911 ! cytokinesis GO:0000910 52 33 0,000 0,04255261 0,05276065 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04255261 0,05273222 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04381465 0,05426693 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04381465 0,05423773 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04381465 0,05420855 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04381465 0,05417941 ! feeding behavior GO:0007631 45 34 0,000 0,04381465 0,05415029 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04381465 0,05412121 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04381465 0,05409216 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04381465 0,05406314 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04381465 0,05403415 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04381465 0,0540052 ! neuron migration GO:0001764 46 34 0,000 0,04381465 0,05397627 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04381465 0,05394737 ! female gamete generation GO:0007292 43 34 0,000 0,04381465 0,05391851 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04381465 0,05388968 ! polyol metabolic process GO:0019751 44 34 0,000 0,04381465 0,05386087 ! aerobic respiration GO:0009060 47 34 0,000 0,04381465 0,0538321 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04381465 0,05380336 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,04381465 0,05377465 ! embryonic organ development GO:0048568 45 34 0,000 0,04381465 0,05374597 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04381465 0,05371732 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,0450751 0,0552332 ! Notch signaling pathway GO:0007219 56 35 0,000 0,0450751 0,05520379 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,0450751 0,05517441 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,0450751 0,05514506 ! keratinocyte differentiation GO:0030216 47 35 0,000 0,0450751 0,05511575 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0450751 0,05508646 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,0450751 0,05505721 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,0450751 0,05502798 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,0450751 0,05499879 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,0450751 0,05496963 ! glycogen metabolic process GO:0005977 48 35 0,000 0,0450751 0,0549405 ! pigment metabolic process GO:0042440 61 35 0,000 0,0450751 0,0549114 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,0450751 0,05488233 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,0450751 0,05485329 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04633395 0,05635542 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04633395 0,05632563 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04633395 0,05629588 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04633395 0,05626615 ! negative regulation of binding GO:0051100 58 36 0,000 0,04633395 0,05623646 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04633395 0,0562068 ! tissue remodeling GO:0048771 62 36 0,000 0,04633395 0,05617717 ! neural tube development GO:0021915 50 36 0,000 0,04633395 0,05614757 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04633395 0,05611801 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04633395 0,05608847 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04633395 0,05605896 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04633395 0,05602949 ! glucan metabolic process GO:0044042 49 36 0,000 0,04633395 0,05600005 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04759122 0,0574894 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04759122 0,05745922 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04759122 0,05742907 ! learning GO:0007612 67 37 0,000 0,04759122 0,05739896 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04759122 0,05736887 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04759122 0,05733882 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04759122 0,0573088 ! amino acid activation GO:0043038 52 37 0,000 0,04759122 0,05727881 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04759122 0,05724886 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,04884691 0,05872864 ! gliogenesis GO:0042063 71 38 0,000 0,04884691 0,05869795 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,04884691 0,0586673 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,04884691 0,05863668 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,04884691 0,05860609 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,04884691 0,05857554 ! phagocytosis GO:0006909 60 38 0,000 0,04884691 0,05854501 ! mesenchymal cell development GO:0014031 64 38 0,000 0,04884691 0,05851452 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,04884691 0,05848406 ! maintenance of location in cell GO:0051651 69 38 0,000 0,04884691 0,05845363 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,05010101 0,0599232 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05010101 0,05989205 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05010101 0,05986094 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,05010101 0,05982986 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05010101 0,05979881 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,05010101 0,0597678 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,05010101 0,05973681 ! male sex differentiation GO:0046661 53 39 0,000 0,05010101 0,05970586 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05010101 0,05967494 ! chromatin remodeling GO:0006338 68 39 0,000 0,05010101 0,05964405 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05010101 0,0596132 ! JNK cascade GO:0007254 54 39 0,000 0,05010101 0,05958238 ! developmental growth GO:0048589 62 39 0,000 0,05010101 0,05955158 ! cell growth GO:0016049 61 39 0,000 0,05010101 0,05952082 ! synapse organization GO:0050808 55 39 0,000 0,05010101 0,05949009 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,05135352 0,06094587 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,05135352 0,06091444 ! regulation of tube size GO:0035150 60 40 0,000 0,05135352 0,06088304 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,05135352 0,06085168 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,05135352 0,06082034 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,05135352 0,06078904 ! peptide metabolic process GO:0006518 56 40 0,000 0,05135352 0,06075777 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,05135352 0,06072653 ! inner ear development GO:0048839 57 40 0,000 0,05135352 0,06069533 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,05135352 0,06066415 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,05135352 0,06063301 ! double-strand break repair GO:0006302 67 40 0,000 0,05135352 0,0606019 ! B cell differentiation GO:0030183 62 40 0,000 0,05135352 0,06057082 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,05135352 0,06053978 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,05135352 0,06050876 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,05135352 0,06047778 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,05260446 0,06191928 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05260446 0,0618876 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05260446 0,06185596 ! glucose transport GO:0015758 52 41 0,000 0,05260446 0,06182436 ! endosome transport GO:0016197 71 41 0,000 0,05260446 0,06179278 ! striated muscle contraction GO:0006941 62 41 0,000 0,05260446 0,06176124 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05260446 0,06172973 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05260446 0,06169825 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05260446 0,0616668 ! biopolymer methylation GO:0043414 62 41 0,000 0,05260446 0,06163539 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,05260446 0,061604 ! mitochondrial transport GO:0006839 60 42 0,000 0,05385382 0,06303501 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,05385382 0,06300295 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,05385382 0,06297092 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05385382 0,06293892 ! cellular component disassembly GO:0022411 64 42 0,000 0,05385382 0,06290695 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,05385382 0,06287502 ! hexose transport GO:0008645 54 42 0,000 0,05385382 0,06284312 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,05385382 0,06281125 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,05385382 0,06277942 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05385382 0,06274762 ! excretion GO:0007588 63 42 0,000 0,05385382 0,06271584 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05385382 0,06268411 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05385382 0,0626524 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05385382 0,06262072 ! regulation of cell shape GO:0008360 78 42 0,000 0,05385382 0,06258908 ! positive regulation of binding GO:0051099 59 43 0,000 0,05510161 0,06400692 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05510161 0,06397461 ! leukocyte migration GO:0050900 60 43 0,000 0,05510161 0,06394233 ! neuromuscular process GO:0050905 79 43 0,000 0,05510161 0,06391008 ! activation of caspase activity GO:0006919 65 43 0,000 0,05510161 0,06387787 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05510161 0,06384569 ! tRNA processing GO:0008033 49 43 0,000 0,05510161 0,06381354 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05510161 0,06378143 ! vesicle organization GO:0016050 79 43 0,000 0,05510161 0,06374934 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05510161 0,06371729 ! methylation GO:0032259 64 43 0,000 0,05510161 0,06368528 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,05634782 0,06509291 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,05634782 0,06506023 ! regulation of action potential GO:0001508 71 44 0,000 0,05634782 0,06502759 ! regulation of ion transport GO:0043269 57 44 0,000 0,05634782 0,06499498 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,05634782 0,0649624 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,05634782 0,06492985 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,05634782 0,06489734 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,05634782 0,06486486 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,05634782 0,06483241 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,05634782 0,06479999 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,05634782 0,06476761 ! positive regulation of defense response GO:0031349 59 45 0,000 0,05759246 0,06616516 ! regulation of translational initiation GO:0006446 64 45 0,000 0,05759246 0,06613213 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,05759246 0,06609913 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,05759246 0,06606616 ! cell recognition GO:0008037 58 45 0,000 0,05759246 0,06603323 ! cell maturation GO:0048469 60 45 0,000 0,05759246 0,06600032 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,05759246 0,06596745 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,05883552 0,06735774 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,05883552 0,06732423 ! cell redox homeostasis GO:0045454 63 46 0,000 0,05883552 0,06729075 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,05883552 0,06725731 ! regulation of ossification GO:0030278 71 46 0,000 0,05883552 0,0672239 ! histone modification GO:0016570 68 46 0,000 0,05883552 0,06719052 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,05883552 0,06715717 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,06007702 0,06854025 ! viral infectious cycle GO:0019058 71 47 0,000 0,06007702 0,06850627 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,06007702 0,06847233 ! endocrine system development GO:0035270 83 47 0,000 0,06007702 0,06843841 ! covalent chromatin modification GO:0016569 75 47 0,000 0,06007702 0,06840453 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,06007702 0,06837068 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,06007702 0,06833687 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,06007702 0,06830309 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,06007702 0,06826934 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,06007702 0,06823563 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,06007702 0,06820195 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,06007702 0,0681683 ! chloride transport GO:0006821 67 48 0,000 0,06131696 0,06954093 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,06131696 0,06950665 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,06131696 0,06947241 ! response to temperature stimulus GO:0009266 62 48 0,000 0,06131696 0,06943821 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,06131696 0,06940404 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,06131696 0,0693699 ! gastrulation GO:0007369 73 48 0,000 0,06131696 0,06933579 ! heart morphogenesis GO:0003007 65 48 0,000 0,06131696 0,06930172 ! regulation of DNA replication GO:0006275 75 48 0,000 0,06131696 0,06926768 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,06131696 0,06923368 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,06131696 0,06919971 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,06131696 0,06916577 ! regulation of endocytosis GO:0030100 63 48 0,000 0,06131696 0,06913186 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,06131696 0,06909799 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,06131696 0,06906415 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,06255532 0,0704245 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,06255532 0,07039004 ! sensory perception of smell GO:0007608 61 49 0,000 0,06255532 0,07035562 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,06255532 0,07032123 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06255532 0,07028688 ! RNA elongation GO:0006354 62 49 0,000 0,06255532 0,07025256 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,06255532 0,07021828 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,06255532 0,07018402 ! germ cell development GO:0007281 68 49 0,000 0,06255532 0,0701498 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,06255532 0,07011562 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,06255532 0,07008146 ! maintenance of location GO:0051235 84 49 0,000 0,06255532 0,07004734 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06379213 0,07139752 ! ear development GO:0043583 72 50 0,000 0,06379213 0,07136279 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,06379213 0,0713281 ! membrane fusion GO:0006944 80 50 0,000 0,06379213 0,07129344 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06379213 0,07125881 ! lipid modification GO:0030258 73 50 0,000 0,06379213 0,07122422 ! positive regulation of growth GO:0045927 67 50 0,000 0,06379213 0,07118966 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06379213 0,07115514 ! proton transport GO:0015992 75 50 0,000 0,06379213 0,07112065 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06379213 0,07108619 ! positive regulation of secretion GO:0051047 71 51 0,000 0,06502737 0,07242758 ! hydrogen transport GO:0006818 77 51 0,000 0,06502737 0,07239253 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,06502737 0,0723575 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,06502737 0,07232251 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,06502737 0,07228756 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,06502737 0,07225264 ! adult behavior GO:0030534 80 51 0,000 0,06502737 0,07221775 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,06502737 0,0721829 ! transition metal ion transport GO:0000041 74 52 0,000 0,06626106 0,07351685 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06626106 0,07348141 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06626106 0,07344599 ! aging GO:0007568 79 52 0,000 0,06626106 0,07341062 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,06626106 0,07337527 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06626106 0,07333996 ! establishment of organelle localization GO:0051656 85 52 0,000 0,06626106 0,07330468 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,06749319 0,07463189 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,06749319 0,07459603 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,06749319 0,0745602 ! kidney development GO:0001822 90 53 0,000 0,06749319 0,0745244 ! single fertilization GO:0007338 59 53 0,000 0,06749319 0,07448864 ! amino acid transport GO:0006865 84 54 0,000 0,06872376 0,07581038 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,06872376 0,07577404 ! regulation of mitosis GO:0007088 84 54 0,000 0,06872376 0,07573773 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,06872376 0,07570146 ! DNA catabolic process GO:0006308 67 54 0,000 0,06872376 0,07566522 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,06872376 0,07562902 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,06872376 0,07559285 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,06872376 0,07555672 ! exocytosis GO:0006887 74 55 0,000 0,06995278 0,07687119 ! mesoderm development GO:0007498 76 55 0,000 0,06995278 0,07683448 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,06995278 0,0767978 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,06995278 0,07676116 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,07118025 0,07807085 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,07118025 0,07803364 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,07118025 0,07799646 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,07118025 0,07795932 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,07240617 0,07926425 ! carbohydrate transport GO:0008643 74 57 0,000 0,07240617 0,07922654 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,07240617 0,07918887 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,07240617 0,07915123 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,07240617 0,07911363 ! camera-type eye development GO:0043010 88 57 0,000 0,07240617 0,07907606 ! secondary metabolic process GO:0019748 84 57 0,000 0,07240617 0,07903853 ! developmental maturation GO:0021700 75 57 0,000 0,07240617 0,07900104 ! gonad development GO:0008406 79 57 0,000 0,07240617 0,07896358 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,07363054 0,08026078 ! viral reproductive process GO:0022415 87 58 0,000 0,07363054 0,08022276 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,07363054 0,08018477 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,07363054 0,08014682 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,07363054 0,08010891 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,07485336 0,08140082 ! activation of MAPK activity GO:0000187 84 59 0,000 0,07485336 0,08136235 ! lung development GO:0030324 94 59 0,000 0,07485336 0,08132392 ! actin filament organization GO:0007015 95 59 0,000 0,07485336 0,08128552 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07485336 0,08124716 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,07485336 0,08120884 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,07607464 0,0824949 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,07607464 0,08245602 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,07607464 0,08241718 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,07607464 0,08237838 ! regulation of heart contraction GO:0008016 91 60 0,000 0,07607464 0,08233961 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,07607464 0,08230088 ! fertilization GO:0009566 68 60 0,000 0,07607464 0,08226219 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,07607464 0,08222353 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,07729438 0,08350262 ! meiosis GO:0007126 96 61 0,000 0,07729438 0,08346342 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,07729438 0,08342425 ! urogenital system development GO:0001655 101 61 0,000 0,07729438 0,08338512 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,07729438 0,08334603 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,07729438 0,08330697 ! extracellular matrix organization GO:0030198 103 61 0,000 0,07729438 0,08326795 ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,07729438 0,08322897 ! amine catabolic process GO:0009310 90 62 0,000 0,07851258 0,08450114 ! neurotransmitter transport GO:0006836 81 62 0,000 0,07851258 0,08446161 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,07851258 0,08442213 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,07851258 0,08438268 ! respiratory tube development GO:0030323 99 62 0,000 0,07851258 0,08434327 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,07851258 0,08430389 ! meiotic cell cycle GO:0051321 97 62 0,000 0,07851258 0,08426455 ! organelle localization GO:0051640 96 62 0,000 0,07851258 0,08422525 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,07972924 0,08549056 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,07972924 0,08545072 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,07972924 0,08541092 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,07972924 0,08537116 ! viral reproduction GO:0016032 92 63 0,000 0,07972924 0,08533143 ! regulation of lipase activity GO:0060191 109 63 0,000 0,07972924 0,08529174 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,08094436 0,08655139 ! negative regulation of cell size GO:0045792 108 64 0,000 0,08094436 0,08651117 ! appendage morphogenesis GO:0035107 93 64 0,000 0,08094436 0,08647099 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 0,000 0,08094436 0,08643084 ! adaptive immune response GO:0002250 94 64 0,000 0,08094436 0,08639073 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,08215795 0,08764531 ! regulation of caspase activity GO:0043281 97 65 0,000 0,08215795 0,08760468 ! appendage development GO:0048736 94 65 0,000 0,08215795 0,08756408 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,08215795 0,08752352 ! defense response to bacterium GO:0042742 73 65 0,000 0,08215795 0,087483 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,08215795 0,08744252 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,08215795 0,08740207 ! activation of immune response GO:0002253 83 65 0,000 0,08215795 0,08736167 ! protein oligomerization GO:0051259 100 65 0,000 0,08215795 0,0873213 ! antigen processing and presentation GO:0019882 96 66 0,000 0,08337001 0,0885686 ! regulation of immune effector process GO:0002697 101 66 0,000 0,08337001 0,08852771 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,08458053 0,08977167 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,08458053 0,08973027 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,08458053 0,0896889 ! acute inflammatory response GO:0002526 92 68 0,000 0,08578952 0,09092899 ! learning or memory GO:0007611 123 68 0,000 0,08578952 0,09088711 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,08578952 0,09084526 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,08578952 0,09080345 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,08578952 0,09076169 ! rhythmic process GO:0048511 105 68 0,000 0,08578952 0,09071996 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,08699699 0,09195454 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,08699699 0,0919123 ! response to drug GO:0042493 108 69 0,000 0,08699699 0,0918701 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,08820293 0,09310085 ! humoral immune response GO:0006959 86 70 0,000 0,08820293 0,09305814 ! eye development GO:0001654 111 70 0,000 0,08820293 0,09301547 ! amine transport GO:0015837 101 70 0,000 0,08820293 0,09297285 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,08820293 0,09293026 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,08940735 0,09415609 ! muscle cell differentiation GO:0042692 104 71 0,000 0,08940735 0,094113 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,08940735 0,09406995 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,08940735 0,09402694 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,08940735 0,09398396 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,09061025 0,09520492 ! response to hypoxia GO:0001666 132 72 0,000 0,09061025 0,09516145 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,09061025 0,09511802 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,09061025 0,09507462 ! negative regulation of transport GO:0051051 116 73 0,000 0,09181163 0,09629126 ! regulation of blood pressure GO:0008217 107 73 0,000 0,09181163 0,09624737 ! tube morphogenesis GO:0035239 118 73 0,000 0,09181163 0,09620353 ! mitochondrion organization GO:0007005 104 73 0,000 0,09181163 0,09615972 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,09181163 0,09611595 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,09181163 0,09607222 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,09301148 0,0972835 ! response to oxygen levels GO:0070482 137 74 0,000 0,09301148 0,09723928 ! digestion GO:0007586 97 74 0,000 0,09301148 0,0971951 ! protein import into nucleus GO:0006606 118 74 0,000 0,09301148 0,09715096 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,09301148 0,09710686 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,09301148 0,0970628 ! blood coagulation GO:0007596 116 75 0,000 0,09420983 0,09826875 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,09420983 0,09822421 ! response to nutrient GO:0007584 104 75 0,000 0,09420983 0,0981797 ! nuclear import GO:0051170 121 75 0,000 0,09420983 0,09813524 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,09420983 0,09809081 ! amine biosynthetic process GO:0009309 97 76 0,000 0,09540665 0,09929199 ! tRNA metabolic process GO:0006399 95 76 0,000 0,09540665 0,09924708 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,09540665 0,09920222 ! regulation of protein transport GO:0051223 114 76 0,000 0,09540665 0,09915739 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,09660197 0,10035435 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,09660197 0,10030904 ! regulation of DNA binding GO:0051101 119 77 0,000 0,09660197 0,10026378 ! gland development GO:0048732 148 77 0,000 0,09660197 0,10021855 ! sex differentiation GO:0007548 105 77 0,000 0,09660197 0,10017337 ! protein ubiquitination GO:0016567 125 77 0,000 0,09660197 0,10012822 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,09660197 0,10008312 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,09660197 0,10003806 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,09660197 0,09999304 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,09779577 0,10118321 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,09779577 0,10113771 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,09898807 0,10232474 ! cellular respiration GO:0045333 107 79 0,000 0,09898807 0,10227877 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,09898807 0,10223285 ! T cell activation GO:0042110 134 79 0,000 0,09898807 0,10218696 ! regulation of lyase activity GO:0051339 133 79 0,000 0,09898807 0,10214112 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,09898807 0,10209532 ! chromatin assembly GO:0031497 102 80 0,000 0,10017885 0,10327717 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,10017885 0,1032309 ! forebrain development GO:0030900 131 80 0,000 0,10017885 0,10318467 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,10136814 0,1043629 ! hemostasis GO:0007599 125 81 0,000 0,10136814 0,1043162 ! mRNA transport GO:0051028 121 81 0,000 0,10136814 0,10426955 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,10136814 0,10422294 ! regulation of neurological system process GO:0031644 122 81 0,000 0,10136814 0,10417637 ! vitamin metabolic process GO:0006766 103 81 0,000 0,10136814 0,10412984 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,10136814 0,10408335 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,10255591 0,10525596 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,10374219 0,10642598 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,10374219 0,10637853 ! regulation of defense response GO:0031347 117 84 0,000 0,10492697 0,10754547 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,10492697 0,10749756 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,10492697 0,1074497 ! sterol metabolic process GO:0016125 120 84 0,000 0,10492697 0,10740188 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,10611025 0,10856475 ! rRNA metabolic process GO:0016072 107 85 0,000 0,10611025 0,10851648 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,10611025 0,10846825 ! transcription initiation GO:0006352 118 85 0,000 0,10611025 0,10842007 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,10611025 0,10837192 ! regulation of protein localization GO:0032880 132 85 0,000 0,10611025 0,10832382 ! regulation of membrane potential GO:0042391 128 85 0,000 0,10611025 0,10827576 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,10611025 0,10822775 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,10729203 0,1093846 ! nucleosome organization GO:0034728 114 87 0,000 0,10847232 0,11053891 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,10847232 0,11048996 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,10847232 0,11044105 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,10847232 0,11039218 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,10847232 0,11034336 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,10847232 0,11029457 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,10965111 0,1114439 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,10965111 0,11139468 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,10965111 0,1113455 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,10965111 0,11129636 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,11082841 0,11244171 ! reproductive developmental process GO:0003006 127 89 0,000 0,11082841 0,11239213 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,11082841 0,1123426 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,11082841 0,11229311 ! regulation of T cell activation GO:0050863 128 89 0,000 0,11082841 0,11224366 ! leukocyte differentiation GO:0002521 143 90 0,000 0,11200423 0,11338456 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,11200423 0,11333468 ! hormone metabolic process GO:0042445 121 90 0,000 0,11200423 0,11328484 ! ATP metabolic process GO:0046034 137 91 0,000 0,11317856 0,11442228 ! response to virus GO:0009615 122 91 0,000 0,11317856 0,114372 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,1143514 0,11550646 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,1143514 0,11545576 ! cell fate commitment GO:0045165 141 92 0,000 0,1143514 0,1154051 ! positive regulation of immune response GO:0050778 121 92 0,000 0,1143514 0,11535448 ! DNA recombination GO:0006310 146 92 0,000 0,1143514 0,11530391 ! sulfur metabolic process GO:0006790 118 92 0,000 0,1143514 0,11525338 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,11552276 0,11638298 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,11552276 0,11633202 ! electron transport chain GO:0022900 123 94 0,000 0,11669263 0,11745867 ! response to oxidative stress GO:0006979 141 94 0,000 0,11669263 0,11740729 ! regulation of binding GO:0051098 151 95 0,000 0,11786103 0,11853099 ! angiogenesis GO:0001525 149 95 0,000 0,11786103 0,11847918 ! carboxylic acid transport GO:0046942 147 95 0,000 0,11786103 0,11842742 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,11902795 0,11954772 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,11902795 0,11949554 ! protein maturation GO:0051604 129 96 0,000 0,11902795 0,1194434 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,12019339 0,12056031 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! extracellular structure organization GO:0043062 156 99 0,000 0,12251985 0,1228403 ! protein import GO:0017038 156 99 0,000 0,12251985 0,12278677 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,12368087 0,12389634 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,12368087 0,1238424 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,12368087 0,12378851 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,12368087 0,12373467 ! protein localization in organelle GO:0033365 161 100 0,000 0,12368087 0,12368087