pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5717-7-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glycolysis GO:0006096 65 45 5,000 1,77E-12 4,26E-09 ! glucose catabolic process GO:0006007 82 55 5,000 6,266E-12 7,537E-09 ! hexose catabolic process GO:0019320 104 67 5,000 2,142E-11 1,718E-08 ! monosaccharide catabolic process GO:0046365 115 76 5,000 4,669E-11 2,808E-08 ! alcohol catabolic process GO:0046164 130 86 5,000 9,983E-11 4,804E-08 ! substrate-bound cell migration, cell extension GO:0006930 6 5 2,000 5,705E-09 2,288E-06 ! substrate-bound cell migration GO:0006929 13 11 2,000 9,381E-08 3,224E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 3,422E-07 1,029E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 3,63E-07 9,705E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 4,313E-07 1,038E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 4,313E-07 9,433E-05 ! positive regulation of ligase activity GO:0051351 124 77 3,000 5,656E-07 1,134E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 6,273E-07 1,161E-04 ! regulation of ligase activity GO:0051340 142 84 3,000 8,032E-07 1,38E-04 ! response to unfolded protein GO:0006986 131 85 3,000 8,424E-07 1,351E-04 ! response to protein stimulus GO:0051789 149 91 3,000 1,108E-06 1,666E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 1,209E-06 1,711E-04 GO:0010498|proteasomal protein catabolic process, ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 7,155E-06 9,564E-04 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 7,155E-06 9,061E-04 GO:0032862|activation of Rho GTPase activity, ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 1,501E-05 1,806E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 1,501E-05 1,72E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2E-05 2,188E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 2E-05 2,092E-03 ! cell projection assembly GO:0030031 120 66 2,000 2,521E-05 2,527E-03 ! phosphate transport GO:0006817 19 9 1,000 2,57E-05 2,474E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,57E-05 2,379E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 2,638E-05 2,35E-03 ! negative regulation of ligase activity GO:0051352 112 68 2,000 2,758E-05 2,37E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 3,211E-05 2,664E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 3,211E-05 2,575E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 3,211E-05 2,492E-03 ! axon guidance GO:0007411 139 73 2,000 3,413E-05 2,566E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 3,923E-05 2,86E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 3,923E-05 2,776E-03 ! cartilage condensation GO:0001502 20 12 1,000 4,705E-05 3,234E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 5,557E-05 3,714E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 6,48E-05 4,214E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 8,536E-05 5,405E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 8,536E-05 5,266E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,214E-04 7,305E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 29 20 1,000 1,349E-04 7,914E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,49E-04 8,535E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,793E-04 0,01003246 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,793E-04 9,804E-03 GO:0010810|regulation of cell-substrate adhesion, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 1,955E-04 0,01045252 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,124E-04 0,01110855 ! fat cell differentiation GO:0045444 50 27 1,000 2,482E-04 0,01270697 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,672E-04 0,01339223 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,672E-04 0,01311892 ! response to mechanical stimulus GO:0009612 57 32 1,000 3,498E-04 0,01683417 ! RNA export from nucleus GO:0006405 56 37 1,000 4,685E-04 0,02210201 ! mRNA catabolic process GO:0006402 71 39 1,000 5,207E-04 0,02409249 ! JAK-STAT cascade GO:0007259 71 44 1,000 6,63E-04 0,03009747 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 7,246E-04 0,03228498 ! response to insulin stimulus GO:0032868 95 46 1,000 7,246E-04 0,03169798 ! response to calcium ion GO:0051592 81 47 1,000 7,564E-04 0,03249834 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,889E-04 0,03329871 ! detection of abiotic stimulus GO:0009582 74 49 1,000 8,22E-04 0,03409904 ! cartilage development GO:0051216 90 52 1,000 9,254E-04 0,03773664 ! RNA catabolic process GO:0006401 93 53 1,000 9,612E-04 0,03854246 ! response to UV GO:0009411 104 53 1,000 9,612E-04 0,03791062 ! regulation of protein catabolic process GO:0042176 116 55 1,000 1,035E-03 0,04015278 ! nuclear export GO:0051168 97 55 1,000 1,035E-03 0,03951543 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 1,111E-03 0,04176122 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,19E-03 0,04403484 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 1,19E-03 0,04336764 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 1,19E-03 0,04272037 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,271E-03 0,04497192 ! detection of external stimulus GO:0009581 91 63 1,000 1,355E-03 0,04724893 ! chromosome segregation GO:0007059 113 67 1,000 1,531E-03 0,0526149 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,765E-03 0,05980945 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,863E-03 0,06225857 ! cell-matrix adhesion GO:0007160 163 75 1,000 1,913E-03 0,06305464 ! regulation of catabolic process GO:0009894 161 76 1,000 1,964E-03 0,06384987 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 2,015E-03 0,06464424 ! regulation of actin filament-based process GO:0032970 152 77 1,000 2,015E-03 0,06379366 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,12E-03 0,06623044 ! response to metal ion GO:0010038 140 80 1,000 2,173E-03 0,06702226 ! inorganic anion transport GO:0015698 138 80 1,000 2,173E-03 0,06617388 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,227E-03 0,06696557 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 2,227E-03 0,06613883 ! response to inorganic substance GO:0010035 153 86 1,000 2,505E-03 0,07350553 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,621E-03 0,07597669 ! regulation of cell adhesion GO:0030155 212 89 1,000 2,68E-03 0,07675735 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 3,046E-03 0,08621434 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 3,046E-03 0,08521185 ! detection of stimulus GO:0051606 151 96 1,000 3,109E-03 0,08597906 ! interphase GO:0051325 213 98 1,000 3,237E-03 0,08850595 ! Golgi vesicle transport GO:0048193 207 99 1,000 3,302E-03 0,0892686 ! cell cycle arrest GO:0007050 213 100 1,000 3,368E-03 0,09003063 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,309E-03 0,11393701 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,309E-03 0,11269856 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,309E-03 0,11148675 ! neuron fate determination GO:0048664 7 5 0,000 4,309E-03 0,11030072 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,309E-03 0,10913966 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,309E-03 0,10800279 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,309E-03 0,10688936 ! polyol transport GO:0015791 12 5 0,000 4,309E-03 0,10579865 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,309E-03 0,10472998 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,309E-03 0,10368268 ! response to superoxide GO:0000303 10 5 0,000 4,309E-03 0,10265612 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,309E-03 0,10164968 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,309E-03 0,10066279 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,309E-03 0,09969488 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,309E-03 0,09874541 ! female meiosis GO:0007143 7 5 0,000 4,309E-03 0,09781385 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,309E-03 0,0968997 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,309E-03 0,09600248 ! cobalt ion transport GO:0006824 11 5 0,000 4,309E-03 0,09512172 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,309E-03 0,09425698 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,309E-03 0,09340782 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,309E-03 0,09257382 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,309E-03 0,09175458 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,309E-03 0,09094972 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,309E-03 0,09015885 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,309E-03 0,08938162 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,309E-03 0,08861767 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,309E-03 0,08786668 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,309E-03 0,0871283 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,309E-03 0,08640223 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,309E-03 0,08568816 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,309E-03 0,0849858 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,309E-03 0,08429486 ! negative chemotaxis GO:0050919 14 5 0,000 4,309E-03 0,08361506 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,309E-03 0,08294614 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,309E-03 0,08228784 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,309E-03 0,0816399 ! behavioral response to pain GO:0048266 9 5 0,000 4,309E-03 0,08100209 ! clathrin coat assembly GO:0048268 14 5 0,000 4,309E-03 0,08037417 ! Notch receptor processing GO:0007220 8 5 0,000 4,309E-03 0,07975591 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,309E-03 0,07914708 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,309E-03 0,07854748 ! micturition GO:0060073 9 5 0,000 4,309E-03 0,0779569 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,309E-03 0,07737513 ! copulation GO:0007620 9 5 0,000 4,309E-03 0,07680198 ! glial cell fate commitment GO:0021781 13 5 0,000 4,309E-03 0,07623726 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,309E-03 0,07568079 ! spermidine metabolic process GO:0008216 7 5 0,000 4,309E-03 0,07513238 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,309E-03 0,07459185 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,309E-03 0,07405906 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,309E-03 0,07353381 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,309E-03 0,07301597 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,309E-03 0,07250537 ! grooming behavior GO:0007625 6 5 0,000 4,309E-03 0,07200186 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,309E-03 0,0715053 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,309E-03 0,07101553 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,309E-03 0,07053243 ! response to protozoan GO:0001562 10 5 0,000 4,309E-03 0,07005586 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,309E-03 0,06958569 ! lymph vessel development GO:0001945 10 5 0,000 4,309E-03 0,06912179 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,309E-03 0,06866403 ! endochondral ossification GO:0001958 16 5 0,000 4,309E-03 0,06821229 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,309E-03 0,06776646 ! parathyroid gland development GO:0060017 13 5 0,000 4,309E-03 0,06732641 ! anagen GO:0042640 6 5 0,000 4,309E-03 0,06689205 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,309E-03 0,06646326 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,309E-03 0,06603992 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,309E-03 0,06562195 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,309E-03 0,06520923 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,309E-03 0,06480167 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,309E-03 0,06439918 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,309E-03 0,06400165 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,309E-03 0,063609 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,309E-03 0,06322115 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,309E-03 0,06283799 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,309E-03 0,06245944 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,309E-03 0,06208544 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,309E-03 0,06171588 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,309E-03 0,0613507 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,309E-03 0,06098981 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,309E-03 0,06063315 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,309E-03 0,06028063 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,309E-03 0,05993218 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,309E-03 0,05958775 ! histidine catabolic process GO:0006548 6 5 0,000 4,309E-03 0,05924724 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,309E-03 0,05891061 ! microvillus organization GO:0032528 7 5 0,000 4,309E-03 0,05857778 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,309E-03 0,0582487 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,309E-03 0,05792328 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,309E-03 0,05760149 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,309E-03 0,05728325 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,309E-03 0,0569685 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,309E-03 0,0566572 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,309E-03 0,05634928 ! polyol catabolic process GO:0046174 7 5 0,000 4,309E-03 0,05604469 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,309E-03 0,05574338 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,309E-03 0,05544528 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,309E-03 0,05515036 ! muscle cell migration GO:0014812 8 5 0,000 4,309E-03 0,05485856 ! mitochondrial fission GO:0000266 8 5 0,000 4,309E-03 0,05456983 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,309E-03 0,05428412 ! mRNA transcription GO:0009299 9 5 0,000 4,309E-03 0,05400139 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,309E-03 0,05372159 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,309E-03 0,05344468 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,309E-03 0,0531706 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,309E-03 0,05289933 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,309E-03 0,0526308 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,309E-03 0,05236499 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,309E-03 0,05210185 ! response to food GO:0032094 6 5 0,000 4,309E-03 0,05184134 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,309E-03 0,05158342 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,309E-03 0,05132806 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,309E-03 0,05107521 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,309E-03 0,05082484 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,309E-03 0,05057692 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,309E-03 0,0503314 ! forebrain neuron development GO:0021884 13 5 0,000 4,309E-03 0,05008825 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,309E-03 0,04984744 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,309E-03 0,04960894 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,309E-03 0,0493727 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,309E-03 0,04913871 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,309E-03 0,04890692 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,309E-03 0,04867731 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,309E-03 0,04844985 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,309E-03 0,0482245 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,309E-03 0,04800124 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,309E-03 0,04778004 ! basic amino acid transport GO:0015802 11 5 0,000 4,309E-03 0,04756086 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,309E-03 0,04734369 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,309E-03 0,04712849 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,309E-03 0,04691524 ! depyrimidination GO:0045008 10 5 0,000 4,309E-03 0,04670391 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,309E-03 0,04649447 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,309E-03 0,04628691 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,309E-03 0,04608119 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,309E-03 0,04587729 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,309E-03 0,04567519 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,309E-03 0,04547486 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,309E-03 0,04527628 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,309E-03 0,04507943 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,309E-03 0,04488428 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,309E-03 0,04469081 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,309E-03 0,044499 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,309E-03 0,04430884 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,309E-03 0,04412029 ! response to arsenic GO:0046685 10 5 0,000 4,309E-03 0,04393334 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,309E-03 0,04374797 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,309E-03 0,04356415 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,309E-03 0,04338187 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,309E-03 0,04320112 ! response to cadmium ion GO:0046686 7 5 0,000 4,309E-03 0,04302186 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,309E-03 0,04284408 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,309E-03 0,04266777 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,309E-03 0,0424929 ! decidualization GO:0046697 11 5 0,000 4,309E-03 0,04231946 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,309E-03 0,04214743 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,309E-03 0,04197679 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,309E-03 0,04180753 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,309E-03 0,04163963 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,309E-03 0,04147307 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,309E-03 0,04130784 ! neural tube patterning GO:0021532 7 5 0,000 4,309E-03 0,04114392 ! embryonic cleavage GO:0040016 6 5 0,000 4,309E-03 0,0409813 ! peroxisome fission GO:0016559 5 5 0,000 4,309E-03 0,04081995 ! histone demethylation GO:0016577 10 5 0,000 4,309E-03 0,04065987 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,309E-03 0,04050105 ! mitotic recombination GO:0006312 9 5 0,000 4,309E-03 0,04034345 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,309E-03 0,04018708 ! metaphase plate congression GO:0051310 7 5 0,000 4,309E-03 0,04003192 ! regulation of sterol transport GO:0032371 7 5 0,000 4,309E-03 0,03987795 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,309E-03 0,03972516 ! enteric nervous system development GO:0048484 8 5 0,000 4,309E-03 0,03957354 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,309E-03 0,03942307 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,309E-03 0,03927374 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,309E-03 0,03912554 ! muscle cell proliferation GO:0033002 11 5 0,000 4,309E-03 0,03897845 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,309E-03 0,03883246 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,309E-03 0,03868757 ! plasminogen activation GO:0031639 5 5 0,000 4,309E-03 0,03854375 ! B cell homeostasis GO:0001782 13 5 0,000 4,309E-03 0,03840099 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,309E-03 0,03825929 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,309E-03 0,03811863 ! metaphase GO:0051323 8 5 0,000 4,309E-03 0,037979 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,309E-03 0,03784039 ! cellular response to nutrient GO:0031670 8 5 0,000 4,309E-03 0,03770279 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,309E-03 0,03756619 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,309E-03 0,03743057 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,309E-03 0,03729593 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,309E-03 0,03716225 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,309E-03 0,03702953 ! response to redox state GO:0051775 5 5 0,000 4,309E-03 0,03689775 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,309E-03 0,03676691 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,309E-03 0,03663699 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,309E-03 0,03650799 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,309E-03 0,03637989 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,309E-03 0,03625268 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,309E-03 0,03612637 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,309E-03 0,03600093 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,309E-03 0,03587636 ! striatum development GO:0021756 9 5 0,000 4,309E-03 0,03575265 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,309E-03 0,03562979 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,309E-03 0,03550777 ! glial cell migration GO:0008347 11 5 0,000 4,309E-03 0,03538658 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,309E-03 0,03526622 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,309E-03 0,03514667 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,309E-03 0,03502793 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,309E-03 0,03490999 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,309E-03 0,03479284 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,309E-03 0,03467648 ! neuroprotection GO:0043526 6 5 0,000 4,309E-03 0,03456089 ! neural plate development GO:0001840 8 5 0,000 4,309E-03 0,03444607 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,309E-03 0,03433201 ! regulation of sensory perception GO:0051931 7 5 0,000 4,309E-03 0,03421871 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,309E-03 0,03410614 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,309E-03 0,03399432 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,309E-03 0,03388323 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,309E-03 0,03377286 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,309E-03 0,03366321 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,309E-03 0,03355426 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,309E-03 0,03344603 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,309E-03 0,03333848 ! spindle assembly GO:0051225 6 5 0,000 4,309E-03 0,03323163 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,309E-03 0,03312546 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,309E-03 0,03301996 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,309E-03 0,03291514 ! drug metabolic process GO:0017144 6 5 0,000 4,309E-03 0,03281097 ! stem cell division GO:0017145 11 5 0,000 4,309E-03 0,03270747 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,309E-03 0,03260462 ! organ regeneration GO:0031100 7 5 0,000 4,309E-03 0,03250241 ! carnitine metabolic process GO:0009437 7 5 0,000 4,309E-03 0,03240084 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,309E-03 0,0322999 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,309E-03 0,03219959 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,169E-03 0,0385039 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,169E-03 0,03838506 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,169E-03 0,03826695 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,169E-03 0,03814957 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,169E-03 0,0380329 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,169E-03 0,03791695 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,169E-03 0,0378017 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,169E-03 0,03768715 ! sleep GO:0030431 13 6 0,000 5,169E-03 0,03757329 ! response to oxygen radical GO:0000305 11 6 0,000 5,169E-03 0,03746012 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,169E-03 0,03734763 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,169E-03 0,03723581 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,169E-03 0,03712466 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,169E-03 0,03701417 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,169E-03 0,03690433 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,169E-03 0,03679515 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,169E-03 0,03668661 ! forebrain regionalization GO:0021871 8 6 0,000 5,169E-03 0,0365787 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,169E-03 0,03647144 ! male meiosis GO:0007140 7 6 0,000 5,169E-03 0,03636479 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,169E-03 0,03625877 ! response to zinc ion GO:0010043 9 6 0,000 5,169E-03 0,03615337 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,169E-03 0,03604858 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,169E-03 0,03594439 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,169E-03 0,03584081 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,169E-03 0,03573781 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,169E-03 0,03563541 ! malate metabolic process GO:0006108 11 6 0,000 5,169E-03 0,0355336 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,169E-03 0,03543236 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,169E-03 0,0353317 ! protein refolding GO:0042026 15 6 0,000 5,169E-03 0,03523161 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,169E-03 0,03513209 ! opsonization GO:0008228 8 6 0,000 5,169E-03 0,03503313 ! mating behavior GO:0007617 7 6 0,000 5,169E-03 0,03493472 ! neuron remodeling GO:0016322 15 6 0,000 5,169E-03 0,03483686 ! erythrocyte maturation GO:0043249 7 6 0,000 5,169E-03 0,03473955 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,169E-03 0,03464278 ! equilibrioception GO:0050957 14 6 0,000 5,169E-03 0,03454655 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,169E-03 0,03445086 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,169E-03 0,03435569 ! photoreceptor cell development GO:0042461 10 6 0,000 5,169E-03 0,03426105 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,169E-03 0,03416692 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,169E-03 0,03407331 ! response to interferon-gamma GO:0034341 15 6 0,000 5,169E-03 0,03398022 ! toxin metabolic process GO:0009404 11 6 0,000 5,169E-03 0,03388763 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,169E-03 0,03379554 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,169E-03 0,03370396 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,169E-03 0,03361286 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,169E-03 0,03352226 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,169E-03 0,03343215 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,169E-03 0,03334252 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,169E-03 0,03325337 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,169E-03 0,03316469 ! thymic T cell selection GO:0045061 12 6 0,000 5,169E-03 0,03307649 ! protein lipoylation GO:0009249 10 6 0,000 5,169E-03 0,03298875 ! cysteine metabolic process GO:0006534 10 6 0,000 5,169E-03 0,03290148 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,169E-03 0,03281467 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,169E-03 0,03272831 ! glutamate catabolic process GO:0006538 10 6 0,000 5,169E-03 0,03264241 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,169E-03 0,03255696 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,169E-03 0,03247196 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,169E-03 0,03238739 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,169E-03 0,03230327 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,169E-03 0,03221958 ! hyperosmotic response GO:0006972 9 6 0,000 5,169E-03 0,03213633 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,169E-03 0,0320535 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,169E-03 0,0319711 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,169E-03 0,03188913 ! urea metabolic process GO:0019627 7 6 0,000 5,169E-03 0,03180757 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,169E-03 0,03172643 ! neutrophil activation GO:0042119 8 6 0,000 5,169E-03 0,0316457 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,169E-03 0,03156538 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,169E-03 0,03148547 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,169E-03 0,03140596 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,169E-03 0,03132685 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,169E-03 0,03124814 ! neuron apoptosis GO:0051402 9 6 0,000 5,169E-03 0,03116982 ! nucleoside salvage GO:0043174 9 6 0,000 5,169E-03 0,0310919 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,169E-03 0,03101436 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,169E-03 0,03093721 ! T cell mediated immunity GO:0002456 16 6 0,000 5,169E-03 0,03086045 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,169E-03 0,03078406 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,169E-03 0,03070805 ! carnitine transport GO:0015879 10 6 0,000 5,169E-03 0,03063241 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,169E-03 0,03055715 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,169E-03 0,03048225 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,169E-03 0,03040773 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,169E-03 0,03033356 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,169E-03 0,03025976 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,169E-03 0,03018631 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,169E-03 0,03011322 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,169E-03 0,03004048 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,169E-03 0,0299681 ! establishment of spindle localization GO:0051293 12 6 0,000 5,169E-03 0,02989606 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,169E-03 0,02982436 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,169E-03 0,02975301 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,169E-03 0,029682 ! neural nucleus development GO:0048857 14 6 0,000 5,169E-03 0,02961133 ! response to UV-C GO:0010225 11 6 0,000 5,169E-03 0,029541 ! astrocyte development GO:0014002 15 6 0,000 5,169E-03 0,02947099 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,169E-03 0,02940132 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,169E-03 0,02933198 ! interaction with symbiont GO:0051702 13 6 0,000 5,169E-03 0,02926296 ! regulation of dendrite development GO:0050773 16 6 0,000 5,169E-03 0,02919427 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,169E-03 0,0291259 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,169E-03 0,02905785 ! response to copper ion GO:0046688 10 6 0,000 5,169E-03 0,02899012 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,169E-03 0,0289227 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,169E-03 0,02885559 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,169E-03 0,0287888 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,169E-03 0,02872231 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,169E-03 0,02865613 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,169E-03 0,02859025 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,169E-03 0,02852468 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,169E-03 0,0284594 ! hair follicle maturation GO:0048820 7 6 0,000 5,169E-03 0,02839443 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,169E-03 0,02832975 ! Schwann cell development GO:0014044 15 6 0,000 5,169E-03 0,02826536 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,169E-03 0,02820127 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,169E-03 0,02813747 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,169E-03 0,02807395 ! subpallium development GO:0021544 10 6 0,000 5,169E-03 0,02801072 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,169E-03 0,02794777 ! histone ubiquitination GO:0016574 8 6 0,000 5,169E-03 0,02788511 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,169E-03 0,02782273 ! maintenance of organ identity GO:0048496 9 6 0,000 5,169E-03 0,02776062 ! G2 phase GO:0051319 16 6 0,000 5,169E-03 0,0276988 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,169E-03 0,02763724 ! establishment of planar polarity GO:0001736 7 6 0,000 5,169E-03 0,02757596 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,169E-03 0,02751495 ! membrane to membrane docking GO:0022614 14 6 0,000 5,169E-03 0,02745422 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,169E-03 0,02739374 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,169E-03 0,02733354 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,169E-03 0,0272736 ! receptor internalization GO:0031623 10 6 0,000 5,169E-03 0,02721392 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,169E-03 0,0271545 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,169E-03 0,02709534 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,169E-03 0,02703643 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,169E-03 0,02697779 ! protein deubiquitination GO:0016579 14 6 0,000 5,169E-03 0,02691939 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,169E-03 0,02686125 ! protein destabilization GO:0031648 9 6 0,000 5,169E-03 0,02680336 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,169E-03 0,02674572 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,169E-03 0,02668833 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,169E-03 0,02663118 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,169E-03 0,02657427 ! progesterone metabolic process GO:0042448 10 6 0,000 5,169E-03 0,02651761 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,169E-03 0,02646119 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,169E-03 0,02640501 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,169E-03 0,02634907 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,169E-03 0,02629336 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,169E-03 0,02623789 ! determination of adult lifespan GO:0008340 15 6 0,000 5,169E-03 0,02618265 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,169E-03 0,02612765 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,169E-03 0,02607287 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,169E-03 0,02601833 ! catecholamine transport GO:0051937 9 6 0,000 5,169E-03 0,02596401 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,169E-03 0,02590992 ! sensory cilium assembly GO:0035058 10 6 0,000 5,169E-03 0,02585605 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,169E-03 0,02580241 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,169E-03 0,02574898 ! maternal placenta development GO:0001893 12 6 0,000 5,169E-03 0,02569578 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,169E-03 0,0256428 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,169E-03 0,02559004 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,169E-03 0,02553749 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,169E-03 0,02548516 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,169E-03 0,02543305 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,169E-03 0,02538114 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,169E-03 0,02532945 ! tRNA transcription GO:0009304 14 7 0,000 6,028E-03 0,02947873 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,028E-03 0,02941893 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,028E-03 0,02935938 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,028E-03 0,02930007 ! regulation of helicase activity GO:0051095 15 7 0,000 6,028E-03 0,029241 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,028E-03 0,02918216 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,028E-03 0,02912356 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,028E-03 0,0290652 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,028E-03 0,02900707 ! prostate gland development GO:0030850 13 7 0,000 6,028E-03 0,02894917 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,028E-03 0,0288915 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,028E-03 0,02883406 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,028E-03 0,02877685 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,028E-03 0,02871987 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,028E-03 0,02866311 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,028E-03 0,02860658 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,028E-03 0,02855026 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,028E-03 0,02849417 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,028E-03 0,0284383 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,028E-03 0,02838265 ! glycolipid transport GO:0046836 10 7 0,000 6,028E-03 0,02832721 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,028E-03 0,028272 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,028E-03 0,02821699 ! neuron adhesion GO:0007158 12 7 0,000 6,028E-03 0,0281622 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,028E-03 0,02810762 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,028E-03 0,02805326 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,028E-03 0,0279991 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,028E-03 0,02794515 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,028E-03 0,02789141 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,028E-03 0,02783788 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,028E-03 0,02778455 ! mRNA stabilization GO:0048255 18 7 0,000 6,028E-03 0,02773142 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,028E-03 0,0276785 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,028E-03 0,02762578 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,028E-03 0,02757326 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,028E-03 0,02752094 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,028E-03 0,02746881 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,028E-03 0,02741689 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,028E-03 0,02736516 ! lipoprotein transport GO:0042953 14 7 0,000 6,028E-03 0,02731362 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,028E-03 0,02726228 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,028E-03 0,02721113 ! rhythmic behavior GO:0007622 15 7 0,000 6,028E-03 0,02716018 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,028E-03 0,02710941 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,028E-03 0,02705883 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,028E-03 0,02700844 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,028E-03 0,02695824 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,028E-03 0,02690823 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,028E-03 0,0268584 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,028E-03 0,02680875 ! mechanosensory behavior GO:0007638 14 7 0,000 6,028E-03 0,02675929 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,028E-03 0,02671001 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,028E-03 0,02666091 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,028E-03 0,02661199 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,028E-03 0,02656325 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,028E-03 0,02651469 ! spinal cord patterning GO:0021511 13 7 0,000 6,028E-03 0,0264663 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,028E-03 0,02641809 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,028E-03 0,02637006 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,028E-03 0,0263222 ! adrenal gland development GO:0030325 17 7 0,000 6,028E-03 0,02627452 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,028E-03 0,02622701 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,028E-03 0,02617966 ! ovulation GO:0030728 9 7 0,000 6,028E-03 0,02613249 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,028E-03 0,02608549 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,028E-03 0,02603866 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,028E-03 0,025992 ! microtubule nucleation GO:0007020 20 7 0,000 6,028E-03 0,0259455 ! proline biosynthetic process GO:0006561 10 7 0,000 6,028E-03 0,02589917 ! thyroid hormone generation GO:0006590 13 7 0,000 6,028E-03 0,025853 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,028E-03 0,025807 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,028E-03 0,02576116 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,028E-03 0,02571549 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,028E-03 0,02566997 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,028E-03 0,02562462 ! galactose metabolic process GO:0006012 13 7 0,000 6,028E-03 0,02557943 ! vesicle fusion GO:0006906 17 7 0,000 6,028E-03 0,02553439 ! response to dietary excess GO:0002021 8 7 0,000 6,028E-03 0,02548951 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,028E-03 0,0254448 ! intracellular pH reduction GO:0051452 11 7 0,000 6,028E-03 0,02540023 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,028E-03 0,02535583 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,028E-03 0,02531158 ! organ growth GO:0035265 15 7 0,000 6,028E-03 0,02526748 ! purine salvage GO:0043101 10 7 0,000 6,028E-03 0,02522354 ! nucleoside transport GO:0015858 8 7 0,000 6,028E-03 0,02517975 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,028E-03 0,02513611 ! parturition GO:0007567 14 7 0,000 6,028E-03 0,02509262 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,028E-03 0,02504928 ! rRNA modification GO:0000154 14 7 0,000 6,028E-03 0,02500609 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,028E-03 0,02496305 ! spindle checkpoint GO:0031577 15 7 0,000 6,028E-03 0,02492016 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,028E-03 0,02487742 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,028E-03 0,02483482 ! macrophage differentiation GO:0030225 11 7 0,000 6,028E-03 0,02479237 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,028E-03 0,02475006 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,028E-03 0,02470789 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,028E-03 0,02466587 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,028E-03 0,024624 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,028E-03 0,02458226 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,028E-03 0,02454067 ! fibrinolysis GO:0042730 10 7 0,000 6,028E-03 0,02449921 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,028E-03 0,0244579 ! eating behavior GO:0042755 7 7 0,000 6,028E-03 0,02441672 ! B cell lineage commitment GO:0002326 21 7 0,000 6,028E-03 0,02437569 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,028E-03 0,02433479 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,028E-03 0,02429403 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,028E-03 0,0242534 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,028E-03 0,02421291 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,028E-03 0,02417256 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,028E-03 0,02413234 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,028E-03 0,02409225 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,028E-03 0,0240523 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,028E-03 0,02401247 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,028E-03 0,02397278 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,028E-03 0,02393322 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,028E-03 0,0238938 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,028E-03 0,0238545 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,028E-03 0,02381533 ! regulation of meiosis GO:0040020 12 7 0,000 6,028E-03 0,02377629 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,028E-03 0,02373737 ! T cell lineage commitment GO:0002360 16 7 0,000 6,028E-03 0,02369858 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,028E-03 0,02365992 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,028E-03 0,02362139 ! oxygen homeostasis GO:0032364 12 7 0,000 6,028E-03 0,02358298 ! transcription termination GO:0006353 13 7 0,000 6,028E-03 0,0235447 ! response to tumor cell GO:0002347 13 7 0,000 6,028E-03 0,02350654 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,028E-03 0,0234685 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,028E-03 0,02343059 ! anaphase GO:0051322 17 7 0,000 6,028E-03 0,0233928 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,028E-03 0,02335513 ! axonal fasciculation GO:0007413 18 7 0,000 6,028E-03 0,02331758 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,028E-03 0,02328015 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,028E-03 0,02324284 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,028E-03 0,02320565 ! diuresis GO:0030146 12 7 0,000 6,028E-03 0,02316858 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,028E-03 0,02313163 ! thiamin metabolic process GO:0006772 7 7 0,000 6,028E-03 0,0230948 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,028E-03 0,02305808 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,028E-03 0,02302148 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,028E-03 0,022985 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,028E-03 0,02294863 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,028E-03 0,02291238 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,028E-03 0,02287624 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,028E-03 0,02284021 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,028E-03 0,0228043 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,028E-03 0,0227685 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,028E-03 0,02273281 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,028E-03 0,02269724 ! lymph node development GO:0048535 10 7 0,000 6,028E-03 0,02266177 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,028E-03 0,02262642 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,028E-03 0,02259117 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,028E-03 0,02255604 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,028E-03 0,02252102 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,028E-03 0,0224861 ! adult feeding behavior GO:0008343 9 7 0,000 6,028E-03 0,02245129 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,028E-03 0,02241659 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,028E-03 0,022382 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,028E-03 0,02234751 ! muscle adaptation GO:0043500 14 7 0,000 6,028E-03 0,02231313 ! embryonic heart tube development GO:0035050 10 7 0,000 6,028E-03 0,02227885 ! retina homeostasis GO:0001895 12 7 0,000 6,028E-03 0,02224468 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,028E-03 0,02221062 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,028E-03 0,02217666 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,028E-03 0,0221428 ! protein prenylation GO:0018342 18 7 0,000 6,028E-03 0,02210905 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,028E-03 0,02207539 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,028E-03 0,02204185 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,028E-03 0,0220084 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,886E-03 0,02510393 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,886E-03 0,02506595 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,886E-03 0,02502809 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,886E-03 0,02499034 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,886E-03 0,0249527 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,886E-03 0,02491518 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,886E-03 0,02487777 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,886E-03 0,02484047 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,886E-03 0,02480328 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,886E-03 0,02476621 ! meiotic prophase I GO:0007128 13 8 0,000 6,886E-03 0,02472924 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,886E-03 0,02469239 ! oligopeptide transport GO:0006857 15 8 0,000 6,886E-03 0,02465564 ! UTP metabolic process GO:0046051 8 8 0,000 6,886E-03 0,02461901 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,886E-03 0,02458248 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,886E-03 0,02454606 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,886E-03 0,02450975 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,886E-03 0,02447355 ! succinate metabolic process GO:0006105 14 8 0,000 6,886E-03 0,02443745 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,886E-03 0,02440146 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,886E-03 0,02436558 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,886E-03 0,0243298 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,886E-03 0,02429412 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,886E-03 0,02425855 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,886E-03 0,02422309 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,886E-03 0,02418773 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,886E-03 0,02415247 ! reflex GO:0060004 16 8 0,000 6,886E-03 0,02411731 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,886E-03 0,02408226 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,886E-03 0,0240473 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,886E-03 0,02401245 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,886E-03 0,0239777 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,886E-03 0,02394305 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,886E-03 0,0239085 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,886E-03 0,02387405 ! pigment granule organization GO:0048753 16 8 0,000 6,886E-03 0,0238397 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,886E-03 0,02380545 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,886E-03 0,02377129 ! astrocyte differentiation GO:0048708 18 8 0,000 6,886E-03 0,02373724 ! histidine metabolic process GO:0006547 16 8 0,000 6,886E-03 0,02370328 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,886E-03 0,02366942 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,886E-03 0,02363565 ! glycine catabolic process GO:0006546 13 8 0,000 6,886E-03 0,02360198 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,886E-03 0,02356841 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,886E-03 0,02353493 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,886E-03 0,02350155 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,886E-03 0,02346826 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,886E-03 0,02343507 ! melanin metabolic process GO:0006582 15 8 0,000 6,886E-03 0,02340197 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,886E-03 0,02336896 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,886E-03 0,02333605 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,886E-03 0,02330322 ! macrophage activation GO:0042116 12 8 0,000 6,886E-03 0,02327049 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,886E-03 0,02323786 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,886E-03 0,02320531 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,886E-03 0,02317286 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,886E-03 0,02314049 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,886E-03 0,02310822 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,886E-03 0,02307603 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,886E-03 0,02304394 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,886E-03 0,02301193 ! osteoblast development GO:0002076 16 8 0,000 6,886E-03 0,02298002 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,886E-03 0,02294819 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,886E-03 0,02291645 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,886E-03 0,0228848 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,886E-03 0,02285323 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,886E-03 0,02282175 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,886E-03 0,02279036 ! response to UV-B GO:0010224 16 8 0,000 6,886E-03 0,02275906 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,886E-03 0,02272784 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,886E-03 0,0226967 ! intermediate filament organization GO:0045109 12 8 0,000 6,886E-03 0,02266565 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,886E-03 0,02263469 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,886E-03 0,02260381 ! cellular extravasation GO:0045123 12 8 0,000 6,886E-03 0,02257301 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,886E-03 0,0225423 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,886E-03 0,02251167 ! response to antibiotic GO:0046677 11 8 0,000 6,886E-03 0,02248113 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,886E-03 0,02245067 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,886E-03 0,02242029 ! DNA topological change GO:0006265 12 8 0,000 6,886E-03 0,02238999 ! response to tropane GO:0014073 15 8 0,000 6,886E-03 0,02235977 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,886E-03 0,02232964 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,886E-03 0,02229959 ! melanosome transport GO:0032402 13 8 0,000 6,886E-03 0,02226961 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,886E-03 0,02223972 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,886E-03 0,02220991 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,886E-03 0,02218018 ! mast cell activation GO:0045576 14 8 0,000 6,886E-03 0,02215052 ! multicellular organismal aging GO:0010259 18 8 0,000 6,886E-03 0,02212095 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,886E-03 0,02209146 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,886E-03 0,02206204 ! nucleosome disassembly GO:0006337 14 8 0,000 6,886E-03 0,0220327 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,886E-03 0,02200344 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,886E-03 0,02197426 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,886E-03 0,02194516 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,886E-03 0,02191613 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,886E-03 0,02188718 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,886E-03 0,0218583 ! intracellular lipid transport GO:0032365 13 8 0,000 6,886E-03 0,0218295 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,886E-03 0,02180078 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,886E-03 0,02177213 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,886E-03 0,02174356 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,886E-03 0,02171506 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,886E-03 0,02168664 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,886E-03 0,02165829 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,886E-03 0,02163002 ! hormone catabolic process GO:0042447 17 8 0,000 6,886E-03 0,02160182 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,886E-03 0,02157369 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,886E-03 0,02154563 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,886E-03 0,02151765 ! ATP catabolic process GO:0006200 11 8 0,000 6,886E-03 0,02148974 ! blastocyst growth GO:0001832 19 8 0,000 6,886E-03 0,02146191 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,886E-03 0,02143414 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,886E-03 0,02140645 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,886E-03 0,02137883 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,886E-03 0,02135128 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,886E-03 0,0213238 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,886E-03 0,02129639 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,886E-03 0,02126905 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,886E-03 0,02124179 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,886E-03 0,02121459 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,886E-03 0,02118746 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,886E-03 0,0211604 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,886E-03 0,02113341 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,886E-03 0,02110649 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,886E-03 0,02107963 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,886E-03 0,02105285 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,886E-03 0,02102613 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,886E-03 0,02099948 ! regulation of developmental growth GO:0048638 15 9 0,000 7,744E-03 0,02358473 ! axon extension GO:0048675 15 9 0,000 7,744E-03 0,02355491 ! autophagic vacuole formation GO:0000045 15 9 0,000 7,744E-03 0,02352517 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,744E-03 0,02349551 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 7,744E-03 0,02346591 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 7,744E-03 0,0234364 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,744E-03 0,02340695 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 7,744E-03 0,02337759 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 7,744E-03 0,02334829 ! cell proliferation in forebrain GO:0021846 15 9 0,000 7,744E-03 0,02331907 ! reproductive behavior GO:0019098 19 9 0,000 7,744E-03 0,02328992 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,744E-03 0,02326084 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 7,744E-03 0,02323184 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,744E-03 0,02320291 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 7,744E-03 0,02317405 ! GTP metabolic process GO:0046039 9 9 0,000 7,744E-03 0,02314526 ! RNA methylation GO:0001510 15 9 0,000 7,744E-03 0,02311655 ! elastic fiber assembly GO:0048251 15 9 0,000 7,744E-03 0,0230879 ! induction of positive chemotaxis GO:0050930 15 9 0,000 7,744E-03 0,02305933 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 7,744E-03 0,02303082 ! artery development GO:0060840 24 9 0,000 7,744E-03 0,02300239 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 7,744E-03 0,02297403 ! regulation of glycolysis GO:0006110 21 9 0,000 7,744E-03 0,02294573 ! cerebral cortex cell migration GO:0021795 15 9 0,000 7,744E-03 0,02291751 ! keratinocyte proliferation GO:0043616 14 9 0,000 7,744E-03 0,02288936 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 7,744E-03 0,02286127 ! chemosensory behavior GO:0007635 20 9 0,000 7,744E-03 0,02283326 ! microtubule bundle formation GO:0001578 21 9 0,000 7,744E-03 0,02280531 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,744E-03 0,02277743 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 7,744E-03 0,02274962 ! leukocyte degranulation GO:0043299 16 9 0,000 7,744E-03 0,02272187 ! bile acid and bile salt transport GO:0015721 13 9 0,000 7,744E-03 0,0226942 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 7,744E-03 0,02266659 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 7,744E-03 0,02263905 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,744E-03 0,02261157 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,744E-03 0,02258417 ! protein targeting to ER GO:0045047 22 9 0,000 7,744E-03 0,02255682 ! ceramide biosynthetic process GO:0046513 19 9 0,000 7,744E-03 0,02252955 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 7,744E-03 0,02250234 ! T cell selection GO:0045058 23 9 0,000 7,744E-03 0,02247519 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 7,744E-03 0,02244812 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 7,744E-03 0,0224211 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,744E-03 0,02239415 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 7,744E-03 0,02236727 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,744E-03 0,02234045 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,744E-03 0,0223137 ! mannose metabolic process GO:0006013 13 9 0,000 7,744E-03 0,022287 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 7,744E-03 0,02226038 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 7,744E-03 0,02223381 ! Rac protein signal transduction GO:0016601 17 9 0,000 7,744E-03 0,02220731 ! receptor clustering GO:0043113 18 9 0,000 7,744E-03 0,02218088 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 7,744E-03 0,0221545 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,744E-03 0,02212819 ! ruffle organization GO:0031529 15 9 0,000 7,744E-03 0,02210194 ! retinol metabolic process GO:0042572 18 9 0,000 7,744E-03 0,02207575 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 7,744E-03 0,02204963 ! behavioral fear response GO:0001662 22 9 0,000 7,744E-03 0,02202357 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 7,744E-03 0,02199756 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 7,744E-03 0,02197162 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 7,744E-03 0,02194574 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 7,744E-03 0,02191992 ! protein heterooligomerization GO:0051291 16 9 0,000 7,744E-03 0,02189417 ! oligodendrocyte development GO:0014003 10 9 0,000 7,744E-03 0,02186847 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 7,744E-03 0,02184283 ! segment specification GO:0007379 13 9 0,000 7,744E-03 0,02181726 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,744E-03 0,02179174 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 7,744E-03 0,02176628 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,744E-03 0,02174088 ! response to amine stimulus GO:0014075 13 9 0,000 7,744E-03 0,02171554 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,744E-03 0,02169026 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 7,744E-03 0,02166504 ! erythrocyte development GO:0048821 15 9 0,000 7,744E-03 0,02163988 ! gas homeostasis GO:0033483 16 9 0,000 7,744E-03 0,02161478 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,744E-03 0,02158973 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 7,744E-03 0,02156474 ! renal water homeostasis GO:0003091 14 9 0,000 7,744E-03 0,02153981 ! postreplication repair GO:0006301 22 9 0,000 7,744E-03 0,02151494 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 7,744E-03 0,02149012 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 7,744E-03 0,02146536 ! icosanoid secretion GO:0032309 15 9 0,000 7,744E-03 0,02144066 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 7,744E-03 0,02141602 ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,744E-03 0,02139143 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 7,744E-03 0,0213669 ! regulation of cell division GO:0051302 15 9 0,000 7,744E-03 0,02134242 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 7,744E-03 0,021318 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,744E-03 0,02129364 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,744E-03 0,02126933 ! sterol catabolic process GO:0016127 11 9 0,000 7,744E-03 0,02124508 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,744E-03 0,02122088 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 7,744E-03 0,02119674 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 7,744E-03 0,02117265 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 7,744E-03 0,02114862 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 7,744E-03 0,02112464 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 7,744E-03 0,02110072 ! musculoskeletal movement GO:0050881 14 9 0,000 7,744E-03 0,02107685 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 7,744E-03 0,02105304 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 7,744E-03 0,02102927 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,744E-03 0,02100556 ! purine base metabolic process GO:0006144 21 9 0,000 7,744E-03 0,02098191 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 7,744E-03 0,02095831 ! pigment granule transport GO:0051904 17 9 0,000 7,744E-03 0,02093476 ! regulation of fibrinolysis GO:0051917 16 9 0,000 7,744E-03 0,02091126 ! regulation of telomere maintenance GO:0032204 14 9 0,000 7,744E-03 0,02088782 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 7,744E-03 0,02086443 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,744E-03 0,02084109 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,744E-03 0,02081781 ! mitochondrion localization GO:0051646 15 9 0,000 7,744E-03 0,02079457 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,601E-03 0,02306975 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 8,601E-03 0,02304406 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,601E-03 0,02301843 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 8,601E-03 0,02299285 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 8,601E-03 0,02296733 ! synapsis GO:0007129 13 10 0,000 8,601E-03 0,02294187 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,601E-03 0,02291646 ! N-glycan processing GO:0006491 20 10 0,000 8,601E-03 0,02289111 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 8,601E-03 0,02286582 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,601E-03 0,02284058 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,601E-03 0,0228154 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,601E-03 0,02279027 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,601E-03 0,0227652 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,601E-03 0,02274018 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,601E-03 0,02271522 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,601E-03 0,02269031 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,601E-03 0,02266546 ! androgen metabolic process GO:0008209 17 10 0,000 8,601E-03 0,02264066 ! phospholipid efflux GO:0033700 16 10 0,000 8,601E-03 0,02261592 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,601E-03 0,02259123 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,601E-03 0,02256659 ! lung alveolus development GO:0048286 26 10 0,000 8,601E-03 0,02254201 ! pathogenesis GO:0009405 13 10 0,000 8,601E-03 0,02251748 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,601E-03 0,02249301 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,601E-03 0,02246858 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,601E-03 0,02244422 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,601E-03 0,0224199 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,601E-03 0,02239563 ! endoderm development GO:0007492 16 10 0,000 8,601E-03 0,02237142 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,601E-03 0,02234726 ! arginine catabolic process GO:0006527 13 10 0,000 8,601E-03 0,02232316 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,601E-03 0,0222991 ! proline metabolic process GO:0006560 13 10 0,000 8,601E-03 0,0222751 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,601E-03 0,02225115 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,601E-03 0,02222725 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,601E-03 0,0222034 ! V(D)J recombination GO:0033151 28 10 0,000 8,601E-03 0,0221796 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,601E-03 0,02215585 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,601E-03 0,02213216 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 8,601E-03 0,02210851 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,601E-03 0,02208492 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,601E-03 0,02206137 ! multicellular organism growth GO:0035264 18 10 0,000 8,601E-03 0,02203788 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,601E-03 0,02201443 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,601E-03 0,02199104 ! epithelial cell development GO:0002064 20 10 0,000 8,601E-03 0,02196769 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,601E-03 0,0219444 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,601E-03 0,02192115 ! macroautophagy GO:0016236 17 10 0,000 8,601E-03 0,02189795 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,601E-03 0,02187481 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,601E-03 0,02185171 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,601E-03 0,02182866 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,601E-03 0,02180566 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,601E-03 0,0217827 ! copper ion homeostasis GO:0055070 13 10 0,000 8,601E-03 0,0217598 ! regulation of bone resorption GO:0045124 25 10 0,000 8,601E-03 0,02173694 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,601E-03 0,02171413 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,601E-03 0,02169137 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,601E-03 0,02166866 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,601E-03 0,02164599 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,601E-03 0,02162337 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,601E-03 0,0216008 ! blastoderm segmentation GO:0007350 18 10 0,000 8,601E-03 0,02157828 ! response to dsRNA GO:0043331 20 10 0,000 8,601E-03 0,0215558 ! DNA ligation GO:0006266 19 10 0,000 8,601E-03 0,02153337 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,601E-03 0,02151098 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,601E-03 0,02148865 ! melanosome localization GO:0032400 16 10 0,000 8,601E-03 0,02146636 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,601E-03 0,02144411 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,601E-03 0,02142191 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,601E-03 0,02139976 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,601E-03 0,02137765 ! mRNA cleavage GO:0006379 17 10 0,000 8,601E-03 0,02135559 ! protein sumoylation GO:0016925 15 10 0,000 8,601E-03 0,02133357 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,601E-03 0,0213116 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,601E-03 0,02128968 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,601E-03 0,0212678 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,601E-03 0,02124596 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,601E-03 0,02122417 ! salivary gland development GO:0007431 27 10 0,000 8,601E-03 0,02120242 ! prophase GO:0051324 15 10 0,000 8,601E-03 0,02118072 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,601E-03 0,02115907 ! apical protein localization GO:0045176 15 10 0,000 8,601E-03 0,02113745 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,601E-03 0,02111588 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,601E-03 0,02109436 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,601E-03 0,02107288 ! midbrain development GO:0030901 13 10 0,000 8,601E-03 0,02105144 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,601E-03 0,02103005 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,601E-03 0,0210087 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,601E-03 0,02098739 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,601E-03 0,02096613 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,601E-03 0,02094491 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,601E-03 0,02092373 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 8,601E-03 0,02090259 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,601E-03 0,0208815 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,601E-03 0,02086045 ! oocyte development GO:0048599 17 10 0,000 8,601E-03 0,02083944 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,601E-03 0,02081848 ! blastocyst formation GO:0001825 17 10 0,000 8,601E-03 0,02079755 ! cerebellar cortex development GO:0021695 15 10 0,000 8,601E-03 0,02077667 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 8,601E-03 0,02075583 ! activation of innate immune response GO:0002218 12 10 0,000 8,601E-03 0,02073504 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 8,601E-03 0,02071428 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,601E-03 0,02069357 ! response to nicotine GO:0035094 20 10 0,000 8,601E-03 0,02067289 ! establishment of cell polarity GO:0030010 16 10 0,000 8,601E-03 0,02065226 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,601E-03 0,02063167 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,601E-03 0,02061112 ! localization within membrane GO:0051668 20 10 0,000 8,601E-03 0,02059061 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,457E-03 0,02261778 ! respiratory burst GO:0045730 17 11 0,000 9,457E-03 0,02259532 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,457E-03 0,0225729 ! neuron fate specification GO:0048665 17 11 0,000 9,457E-03 0,02255053 ! telencephalon cell migration GO:0022029 20 11 0,000 9,457E-03 0,0225282 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 9,457E-03 0,02250592 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,457E-03 0,02248368 ! thyroid gland development GO:0030878 26 11 0,000 9,457E-03 0,02246149 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,457E-03 0,02243933 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,457E-03 0,02241723 ! Golgi vesicle budding GO:0048194 22 11 0,000 9,457E-03 0,02239516 ! response to pain GO:0048265 24 11 0,000 9,457E-03 0,02237314 ! T cell proliferation GO:0042098 26 11 0,000 9,457E-03 0,02235116 ! blood vessel remodeling GO:0001974 29 11 0,000 9,457E-03 0,02232923 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,457E-03 0,02230734 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 9,457E-03 0,02228549 ! bone resorption GO:0045453 16 11 0,000 9,457E-03 0,02226368 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,457E-03 0,02224192 ! ventral spinal cord development GO:0021517 21 11 0,000 9,457E-03 0,0222202 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,457E-03 0,02219852 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,457E-03 0,02217689 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,457E-03 0,02215529 ! melanocyte differentiation GO:0030318 21 11 0,000 9,457E-03 0,02213374 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,457E-03 0,02211223 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,457E-03 0,02209076 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,457E-03 0,02206934 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,457E-03 0,02204795 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,457E-03 0,02202661 ! lipid digestion GO:0044241 18 11 0,000 9,457E-03 0,0220053 ! UV protection GO:0009650 19 11 0,000 9,457E-03 0,02198404 ! adult heart development GO:0007512 14 11 0,000 9,457E-03 0,02196282 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,457E-03 0,02194164 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,457E-03 0,02192051 ! temperature homeostasis GO:0001659 17 11 0,000 9,457E-03 0,02189941 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,457E-03 0,02187835 ! negative regulation of ossification GO:0030279 26 11 0,000 9,457E-03 0,02185733 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,457E-03 0,02183636 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,457E-03 0,02181542 ! regulation of organ growth GO:0046620 13 11 0,000 9,457E-03 0,02179453 ! pigment granule localization GO:0051875 20 11 0,000 9,457E-03 0,02177367 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,457E-03 0,02175285 ! vasoconstriction GO:0042310 18 11 0,000 9,457E-03 0,02173208 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,457E-03 0,02171134 ! embryonic axis specification GO:0000578 18 11 0,000 9,457E-03 0,02169064 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,457E-03 0,02166999 ! snRNA metabolic process GO:0016073 24 11 0,000 9,457E-03 0,02164937 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,457E-03 0,02162879 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,457E-03 0,02160825 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,457E-03 0,02158775 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,457E-03 0,02156728 ! zymogen activation GO:0031638 15 11 0,000 9,457E-03 0,02154686 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,457E-03 0,02152648 ! neuroblast proliferation GO:0007405 24 11 0,000 9,457E-03 0,02150613 ! nucleosome positioning GO:0016584 15 11 0,000 9,457E-03 0,02148582 ! regulation of isotype switching GO:0045191 22 11 0,000 9,457E-03 0,02146555 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,457E-03 0,02144532 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,457E-03 0,02142513 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,457E-03 0,02140497 ! acid secretion GO:0046717 18 11 0,000 9,457E-03 0,02138485 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,457E-03 0,02136477 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,457E-03 0,02134473 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,457E-03 0,02132473 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,457E-03 0,02130476 ! oocyte differentiation GO:0009994 18 11 0,000 9,457E-03 0,02128483 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,457E-03 0,02126494 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 9,457E-03 0,02124508 ! cholesterol efflux GO:0033344 19 11 0,000 9,457E-03 0,02122527 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,457E-03 0,02120548 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,457E-03 0,02118574 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,457E-03 0,02116603 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,457E-03 0,02114636 ! embryonic gut development GO:0048566 15 11 0,000 9,457E-03 0,02112673 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,457E-03 0,02110713 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,457E-03 0,02108757 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,457E-03 0,02106804 ! defense response to fungus GO:0050832 13 11 0,000 9,457E-03 0,02104855 ! developmental induction GO:0031128 19 11 0,000 9,457E-03 0,0210291 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 9,457E-03 0,02100968 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,457E-03 0,0209903 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,457E-03 0,02097095 ! sequestering of metal ion GO:0051238 14 11 0,000 9,457E-03 0,02095164 ! lamellipodium assembly GO:0030032 20 11 0,000 9,457E-03 0,02093237 ! regulation of embryonic development GO:0045995 27 11 0,000 9,457E-03 0,02091313 ! nucleus localization GO:0051647 19 11 0,000 9,457E-03 0,02089393 ! regulation of synapse organization GO:0050807 17 11 0,000 9,457E-03 0,02087476 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01031242 0,02274216 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01031242 0,02272133 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01031242 0,02270054 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01031242 0,02267979 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01031242 0,02265908 ! virus-host interaction GO:0019048 29 12 0,000 0,01031242 0,02263841 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01031242 0,02261777 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01031242 0,02259717 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01031242 0,02257661 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01031242 0,02255608 ! protein complex disassembly GO:0043241 27 12 0,000 0,01031242 0,0225356 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01031242 0,02251515 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01031242 0,02249474 ! hippocampus development GO:0021766 26 12 0,000 0,01031242 0,02247436 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01031242 0,02245402 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01031242 0,02243372 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01031242 0,02241345 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01031242 0,02239322 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01031242 0,02237303 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01031242 0,02235288 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01031242 0,02233276 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01031242 0,02231267 ! drug transport GO:0015893 16 12 0,000 0,01031242 0,02229263 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01031242 0,02227261 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01031242 0,02225264 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01031242 0,0222327 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01031242 0,0222128 ! focal adhesion formation GO:0048041 35 12 0,000 0,01031242 0,02219293 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01031242 0,02217309 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01031242 0,0221533 ! forebrain cell migration GO:0021885 21 12 0,000 0,01031242 0,02213354 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01031242 0,02211381 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01031242 0,02209412 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01031242 0,02207446 ! entry into host cell GO:0030260 32 12 0,000 0,01031242 0,02205484 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01031242 0,02203525 ! monoamine transport GO:0015844 18 12 0,000 0,01031242 0,0220157 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01031242 0,02199618 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01031242 0,0219767 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01031242 0,02195725 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01031242 0,02193784 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01031242 0,02191846 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01031242 0,02189911 ! protein homotetramerization GO:0051289 21 12 0,000 0,01031242 0,0218798 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01031242 0,02186052 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01031242 0,02184128 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01031242 0,02182207 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01031242 0,02180289 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01031242 0,02178375 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01031242 0,02176464 ! cranial nerve development GO:0021545 20 12 0,000 0,01031242 0,02174557 ! fucose catabolic process GO:0019317 22 12 0,000 0,01031242 0,02172653 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01031242 0,02170752 ! histone acetylation GO:0016573 26 12 0,000 0,01031242 0,02168854 ! histone methylation GO:0016571 26 12 0,000 0,01031242 0,0216696 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01031242 0,02165069 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01031242 0,02163182 ! gland morphogenesis GO:0022612 29 12 0,000 0,01031242 0,02161297 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01031242 0,02159416 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01031242 0,02157539 ! T cell homeostasis GO:0043029 25 12 0,000 0,01031242 0,02155664 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01031242 0,02153793 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01031242 0,02151925 ! spleen development GO:0048536 22 12 0,000 0,01031242 0,0215006 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01031242 0,02148199 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01031242 0,0214634 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01031242 0,02144485 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01031242 0,02142633 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01031242 0,02140785 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01031242 0,02138939 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01031242 0,02137097 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01031242 0,02135258 ! response to cold GO:0009409 17 12 0,000 0,01031242 0,02133422 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01031242 0,02131589 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01031242 0,02129759 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01116716 0,02304305 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01116716 0,0230233 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01116716 0,02300359 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01116716 0,02298391 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01116716 0,02296427 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01116716 0,02294466 ! lipid localization GO:0010876 28 13 0,000 0,01116716 0,02292508 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01116716 0,02290553 ! organelle fusion GO:0048284 32 13 0,000 0,01116716 0,02288602 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01116716 0,02286655 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01116716 0,0228471 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01116716 0,02282769 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01116716 0,02280831 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01116716 0,02278897 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01116716 0,02276965 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01116716 0,02275037 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01116716 0,02273113 ! methionine metabolic process GO:0006555 27 13 0,000 0,01116716 0,02271191 ! plasma membrane organization GO:0007009 24 13 0,000 0,01116716 0,02269273 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01116716 0,02267358 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01116716 0,02265446 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01116716 0,02263538 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01116716 0,02261632 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01116716 0,0225973 ! response to X-ray GO:0010165 25 13 0,000 0,01116716 0,02257831 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01116716 0,02255936 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01116716 0,02254043 ! exocrine system development GO:0035272 32 13 0,000 0,01116716 0,02252154 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01116716 0,02250267 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01116716 0,02248384 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01116716 0,02246504 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01116716 0,02244628 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01116716 0,02242754 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01116716 0,02240883 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01116716 0,02239016 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01116716 0,02237152 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01116716 0,02235291 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01116716 0,02233432 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01116716 0,02231577 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01116716 0,02229725 ! ribosome assembly GO:0042255 17 13 0,000 0,01116716 0,02227877 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01116716 0,02226031 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01116716 0,02224188 ! chromatin silencing GO:0006342 26 13 0,000 0,01116716 0,02222348 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01116716 0,02220512 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01116716 0,02218678 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01116716 0,02216848 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01116716 0,0221502 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01116716 0,02213195 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01116716 0,02211374 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01116716 0,02209555 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01116716 0,0220774 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01116716 0,02205927 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01116716 0,02204117 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01116716 0,02202311 ! embryonic placenta development GO:0001892 23 13 0,000 0,01116716 0,02200507 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01116716 0,02198706 ! insulin secretion GO:0030073 23 13 0,000 0,01116716 0,02196909 ! actin filament polymerization GO:0030041 24 13 0,000 0,01116716 0,02195114 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01116716 0,02193322 ! acrosome reaction GO:0007340 18 13 0,000 0,01116716 0,02191533 ! rRNA transcription GO:0009303 25 14 0,000 0,01202119 0,02357211 ! lactation GO:0007595 26 14 0,000 0,01202119 0,02355292 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01202119 0,02353375 ! reproductive cellular process GO:0048610 20 14 0,000 0,01202119 0,02351462 ! tRNA modification GO:0006400 20 14 0,000 0,01202119 0,02349552 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01202119 0,02347645 ! regulation of S phase GO:0033261 23 14 0,000 0,01202119 0,02345741 ! water transport GO:0006833 21 14 0,000 0,01202119 0,0234384 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01202119 0,02341942 ! non-recombinational repair GO:0000726 25 14 0,000 0,01202119 0,02340047 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01202119 0,02338155 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01202119 0,02336267 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01202119 0,02334381 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01202119 0,02332499 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01202119 0,02330619 ! palate development GO:0060021 31 14 0,000 0,01202119 0,02328743 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01202119 0,02326869 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01202119 0,02324999 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01202119 0,02323131 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01202119 0,02321267 ! arginine metabolic process GO:0006525 17 14 0,000 0,01202119 0,02319405 ! regulation of heart rate GO:0002027 24 14 0,000 0,01202119 0,02317547 ! organic alcohol transport GO:0015850 29 14 0,000 0,01202119 0,02315691 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01202119 0,02313839 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01202119 0,02311989 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01202119 0,02310142 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01202119 0,02308299 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01202119 0,02306458 ! L-amino acid transport GO:0015807 30 14 0,000 0,01202119 0,0230462 ! bone mineralization GO:0030282 17 14 0,000 0,01202119 0,02302785 ! stem cell development GO:0048864 43 14 0,000 0,01202119 0,02300953 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01202119 0,02299124 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01202119 0,02297298 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01202119 0,02295475 ! cerebellum development GO:0021549 21 14 0,000 0,01202119 0,02293654 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01202119 0,02291837 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01202119 0,02290022 ! response to gamma radiation GO:0010332 28 14 0,000 0,01202119 0,02288211 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01202119 0,02286402 ! cofactor transport GO:0051181 26 14 0,000 0,01202119 0,02284596 ! NADP metabolic process GO:0006739 24 14 0,000 0,01202119 0,02282793 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01202119 0,02280992 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01202119 0,02279195 ! intestinal absorption GO:0050892 25 14 0,000 0,01202119 0,022774 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01202119 0,02275608 ! oxygen transport GO:0015671 21 14 0,000 0,01202119 0,02273819 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01202119 0,02272033 ! male genitalia development GO:0030539 24 14 0,000 0,01202119 0,0227025 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01202119 0,02268469 ! regulation of axon extension GO:0030516 37 14 0,000 0,01202119 0,02266691 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01202119 0,02264916 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01202119 0,02263144 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01287451 0,02421897 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01287451 0,02420005 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01287451 0,02418116 ! superoxide anion generation GO:0042554 20 15 0,000 0,01287451 0,0241623 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01287451 0,02414347 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01287451 0,02412466 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01287451 0,02410589 ! copper ion transport GO:0006825 20 15 0,000 0,01287451 0,02408714 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01287451 0,02406843 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01287451 0,02404974 ! sulfate transport GO:0008272 23 15 0,000 0,01287451 0,02403108 ! response to cAMP GO:0051591 22 15 0,000 0,01287451 0,02401246 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01287451 0,02399386 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01287451 0,02397528 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01287451 0,02395674 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01287451 0,02393823 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01287451 0,02391974 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01287451 0,02390129 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01287451 0,02388286 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01287451 0,02386446 ! pituitary gland development GO:0021983 29 15 0,000 0,01287451 0,02384609 ! vesicle coating GO:0006901 33 15 0,000 0,01287451 0,02382774 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01287451 0,02380943 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01287451 0,02379114 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01287451 0,02377288 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01287451 0,02375465 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01287451 0,02373645 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01287451 0,02371828 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01287451 0,02370013 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01287451 0,02368201 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01287451 0,02366392 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01287451 0,02364585 ! histone deacetylation GO:0016575 20 15 0,000 0,01287451 0,02362782 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01287451 0,02360981 ! tissue regeneration GO:0042246 26 15 0,000 0,01287451 0,02359183 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01287451 0,02357387 ! water homeostasis GO:0030104 27 15 0,000 0,01287451 0,02355594 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01287451 0,02353805 ! muscle maintenance GO:0046716 26 15 0,000 0,01287451 0,02352017 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01287451 0,02350233 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01287451 0,02348451 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01287451 0,02346672 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01287451 0,02344895 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01287451 0,02343122 ! cell killing GO:0001906 29 15 0,000 0,01287451 0,02341351 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01287451 0,02339582 ! detection of bacterium GO:0016045 18 15 0,000 0,01287451 0,02337816 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01287451 0,02336053 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01287451 0,02334293 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01287451 0,02332535 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01287451 0,0233078 ! peptide hormone processing GO:0016486 23 15 0,000 0,01287451 0,02329028 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01372712 0,02481401 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01372712 0,02479538 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01372712 0,02477678 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01372712 0,02475821 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01372712 0,02473966 ! bone remodeling GO:0046849 27 16 0,000 0,01372712 0,02472114 ! filopodium assembly GO:0046847 32 16 0,000 0,01372712 0,02470265 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01372712 0,02468419 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01372712 0,02466576 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01372712 0,02464735 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01372712 0,02462897 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01372712 0,02461062 ! startle response GO:0001964 28 16 0,000 0,01372712 0,02459229 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01372712 0,02457399 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01372712 0,02455572 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01372712 0,02453748 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01372712 0,02451926 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01372712 0,02450107 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01372712 0,02448291 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01372712 0,02446478 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01372712 0,02444667 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01372712 0,02442858 ! response to osmotic stress GO:0006970 25 16 0,000 0,01372712 0,02441053 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01372712 0,0243925 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01372712 0,0243745 ! fructose metabolic process GO:0006000 25 16 0,000 0,01372712 0,02435652 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01372712 0,02433858 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01372712 0,02432065 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01372712 0,02430276 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01372712 0,02428489 ! axon cargo transport GO:0008088 43 16 0,000 0,01372712 0,02426704 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01372712 0,02424923 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01372712 0,02423144 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01372712 0,02421367 ! DNA replication initiation GO:0006270 27 16 0,000 0,01372712 0,02419593 ! neuron recognition GO:0008038 35 16 0,000 0,01372712 0,02417822 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01372712 0,02416053 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01372712 0,02414287 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01372712 0,02412524 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01372712 0,02410763 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01372712 0,02409004 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01372712 0,02407248 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01372712 0,02405495 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01372712 0,02403744 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01372712 0,02401996 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01372712 0,0240025 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01372712 0,02398507 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01372712 0,02396767 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01372712 0,02395029 ! defense response to virus GO:0051607 37 16 0,000 0,01372712 0,02393293 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01457902 0,0253998 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01457902 0,02538142 ! metencephalon development GO:0022037 30 17 0,000 0,01457902 0,02536307 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01457902 0,02534474 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01457902 0,02532644 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01457902 0,02530817 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01457902 0,02528992 ! signal complex assembly GO:0007172 41 17 0,000 0,01457902 0,0252717 ! endothelial cell migration GO:0043542 28 17 0,000 0,01457902 0,02525351 ! inositol metabolic process GO:0006020 28 17 0,000 0,01457902 0,02523534 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01457902 0,0252172 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01457902 0,02519908 ! glial cell development GO:0021782 27 17 0,000 0,01457902 0,02518099 ! limbic system development GO:0021761 36 17 0,000 0,01457902 0,02516293 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01457902 0,02514489 ! adult walking behavior GO:0007628 33 17 0,000 0,01457902 0,02512688 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01457902 0,02510889 ! heart looping GO:0001947 30 17 0,000 0,01457902 0,02509093 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01457902 0,025073 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01457902 0,02505509 ! myoblast differentiation GO:0045445 45 17 0,000 0,01457902 0,0250372 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01457902 0,02501935 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01457902 0,02500151 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01457902 0,02498371 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01457902 0,02496592 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01457902 0,02494817 ! glycine metabolic process GO:0006544 28 17 0,000 0,01457902 0,02493044 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01457902 0,02491273 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01457902 0,02489505 ! NAD metabolic process GO:0019674 29 17 0,000 0,01457902 0,02487739 ! membrane budding GO:0006900 37 17 0,000 0,01457902 0,02485976 ! DNA integration GO:0015074 29 17 0,000 0,01457902 0,02484215 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01457902 0,02482457 ! regulation of protein binding GO:0043393 33 17 0,000 0,01457902 0,02480702 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01457902 0,02478949 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01457902 0,02477198 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01457902 0,0247545 ! genitalia development GO:0048806 30 17 0,000 0,01457902 0,02473704 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01457902 0,02471961 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01457902 0,0247022 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01457902 0,02468482 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01457902 0,02466746 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01457902 0,02465012 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01457902 0,02463281 ! steroid catabolic process GO:0006706 31 17 0,000 0,01457902 0,02461552 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01457902 0,02459826 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01457902 0,02458102 ! gas transport GO:0015669 25 17 0,000 0,01457902 0,02456381 ! organic cation transport GO:0015695 31 17 0,000 0,01457902 0,02454662 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01457902 0,02452946 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01457902 0,02451231 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01457902 0,0244952 ! microspike assembly GO:0030035 36 17 0,000 0,01457902 0,0244781 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01457902 0,02446103 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01457902 0,02444399 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01543021 0,02585313 ! neuron maturation GO:0042551 42 18 0,000 0,01543021 0,02583514 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01543021 0,02581717 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01543021 0,02579923 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01543021 0,02578132 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01543021 0,02576343 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01543021 0,02574556 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01543021 0,02572772 ! memory GO:0007613 31 18 0,000 0,01543021 0,0257099 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01543021 0,02569211 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01543021 0,02567434 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01543021 0,0256566 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01543021 0,02563888 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01543021 0,02562118 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01543021 0,02560351 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01543021 0,02558587 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01543021 0,02556825 ! response to retinoic acid GO:0032526 26 18 0,000 0,01543021 0,02555065 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01543021 0,02553308 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01543021 0,02551553 ! response to fungus GO:0009620 21 18 0,000 0,01543021 0,02549801 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01543021 0,0254805 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01543021 0,02546303 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01543021 0,02544558 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01543021 0,02542815 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01543021 0,02541074 ! vitamin transport GO:0051180 27 18 0,000 0,01543021 0,02539336 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01543021 0,02537601 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01543021 0,02535867 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01543021 0,02534136 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01543021 0,02532408 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01543021 0,02530681 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01543021 0,02528957 ! nerve development GO:0021675 28 18 0,000 0,01543021 0,02527236 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01543021 0,02525517 ! protein secretion GO:0009306 39 19 0,000 0,0162807 0,02662907 ! positive regulation of translation GO:0045727 30 19 0,000 0,0162807 0,02661098 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0162807 0,02659292 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0162807 0,02657488 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0162807 0,02655686 ! skin development GO:0043588 36 19 0,000 0,0162807 0,02653887 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0162807 0,0265209 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0162807 0,02650296 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0162807 0,02648504 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0162807 0,02646714 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0162807 0,02644927 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0162807 0,02643142 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0162807 0,0264136 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0162807 0,0263958 ! cerebral cortex development GO:0021987 36 19 0,000 0,0162807 0,02637803 ! pigmentation during development GO:0048066 41 19 0,000 0,0162807 0,02636027 ! response to vitamin A GO:0033189 27 19 0,000 0,0162807 0,02634255 ! heme metabolic process GO:0042168 36 19 0,000 0,0162807 0,02632484 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0162807 0,02630716 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0162807 0,02628951 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0162807 0,02627188 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0162807 0,02625427 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0162807 0,02623668 ! peptide cross-linking GO:0018149 37 19 0,000 0,0162807 0,02621912 ! protein export from nucleus GO:0006611 36 19 0,000 0,0162807 0,02620158 ! heart process GO:0003015 30 19 0,000 0,0162807 0,02618407 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0162807 0,02616658 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0162807 0,02614911 ! visual learning GO:0008542 36 19 0,000 0,0162807 0,02613167 ! cellular pigmentation GO:0033059 36 19 0,000 0,0162807 0,02611425 ! G1 phase GO:0051318 40 19 0,000 0,0162807 0,02609685 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0162807 0,02607947 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0162807 0,02606212 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0162807 0,02604479 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0162807 0,02602749 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0162807 0,0260102 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0162807 0,02599294 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0162807 0,02597571 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0162807 0,02595849 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0162807 0,0259413 ! cilium assembly GO:0042384 37 19 0,000 0,0162807 0,02592413 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0162807 0,02590699 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01713048 0,0272412 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01713048 0,02722321 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01713048 0,02720524 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01713048 0,0271873 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01713048 0,02716937 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01713048 0,02715148 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01713048 0,0271336 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01713048 0,02711575 ! response to vitamin GO:0033273 31 20 0,000 0,01713048 0,02709792 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01713048 0,02708012 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01713048 0,02706234 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01713048 0,02704458 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01713048 0,02702685 ! response to alkaloid GO:0043279 38 20 0,000 0,01713048 0,02700914 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01713048 0,02699145 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01713048 0,02697378 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01713048 0,02695614 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01713048 0,02693852 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01713048 0,02692093 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01713048 0,02690336 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01713048 0,02688581 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01713048 0,02686828 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01713048 0,02685078 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01713048 0,02683329 ! body fluid secretion GO:0007589 31 20 0,000 0,01713048 0,02681584 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01713048 0,0267984 ! peptide secretion GO:0002790 35 20 0,000 0,01713048 0,02678099 ! stem cell differentiation GO:0048863 53 20 0,000 0,01713048 0,0267636 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01713048 0,02674623 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01713048 0,02672888 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01713048 0,02671156 ! sensory perception of pain GO:0019233 30 20 0,000 0,01713048 0,02669426 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01713048 0,02667698 ! diencephalon development GO:0021536 34 20 0,000 0,01713048 0,02665973 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01713048 0,0266425 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01713048 0,02662528 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01713048 0,0266081 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01713048 0,02659093 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01713048 0,02657378 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01713048 0,02655666 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01713048 0,02653956 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01713048 0,02652248 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01713048 0,02650543 ! regulation of glucose import GO:0046324 29 20 0,000 0,01713048 0,02648839 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01713048 0,02647138 ! actin filament-based movement GO:0030048 43 20 0,000 0,01713048 0,02645439 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01713048 0,02643742 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01713048 0,02642047 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01713048 0,02640355 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01713048 0,02638665 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01713048 0,02636976 ! regulation of cell killing GO:0031341 42 21 0,000 0,01797956 0,02765909 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01797956 0,02764142 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01797956 0,02762376 ! hormone secretion GO:0046879 38 21 0,000 0,01797956 0,02760614 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01797956 0,02758853 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01797956 0,02757095 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01797956 0,02755339 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01797956 0,02753585 ! axis specification GO:0009798 38 21 0,000 0,01797956 0,02751833 ! ovarian follicle development GO:0001541 35 21 0,000 0,01797956 0,02750084 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01797956 0,02748336 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01797956 0,02746591 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01797956 0,02744849 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01797956 0,02743108 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01797956 0,0274137 ! cell aging GO:0007569 44 21 0,000 0,01797956 0,02739634 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01797956 0,027379 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01797956 0,02736168 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01797956 0,02734438 ! cytolysis GO:0019835 24 21 0,000 0,01797956 0,02732711 ! vasodilation GO:0042311 39 21 0,000 0,01797956 0,02730986 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01797956 0,02729263 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01797956 0,02727542 ! oogenesis GO:0048477 36 21 0,000 0,01797956 0,02725823 ! DNA modification GO:0006304 34 21 0,000 0,01797956 0,02724107 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01797956 0,02722392 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01797956 0,0272068 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01797956 0,0271897 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01797956 0,02717262 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01797956 0,02715556 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01797956 0,02713853 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01797956 0,02712151 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01797956 0,02710452 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01797956 0,02708755 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01797956 0,0270706 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01797956 0,02705367 ! collagen catabolic process GO:0030574 28 21 0,000 0,01797956 0,02703676 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01797956 0,02701987 ! gut development GO:0048565 39 21 0,000 0,01797956 0,02700301 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01882793 0,02825951 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01882793 0,02824189 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01882793 0,02822429 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01882793 0,02820672 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01882793 0,02818917 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01882793 0,02817164 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01882793 0,02815413 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01882793 0,02813664 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01882793 0,02811918 ! regeneration GO:0031099 41 22 0,000 0,01882793 0,02810173 ! keratinization GO:0031424 28 22 0,000 0,01882793 0,02808431 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01882793 0,02806691 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01882793 0,02804953 ! sensory perception of taste GO:0050909 28 22 0,000 0,01882793 0,02803217 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01882793 0,02801484 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01882793 0,02799752 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01882793 0,02798023 ! vacuolar transport GO:0007034 36 22 0,000 0,01882793 0,02796296 ! lysosome organization GO:0007040 41 22 0,000 0,01882793 0,02794571 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01882793 0,02792848 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01882793 0,02791127 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01882793 0,02789408 ! fucose metabolic process GO:0006004 39 22 0,000 0,01882793 0,02787692 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01882793 0,02785977 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01882793 0,02784265 ! ureteric bud development GO:0001657 43 22 0,000 0,01882793 0,02782555 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01882793 0,02780847 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01882793 0,02779141 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01882793 0,02777437 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01882793 0,02775735 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01882793 0,02774035 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01882793 0,02772337 ! sarcomere organization GO:0045214 30 22 0,000 0,01882793 0,02770642 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01882793 0,02768948 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01882793 0,02767257 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01882793 0,02765567 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01882793 0,0276388 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01882793 0,02762195 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01882793 0,02760511 ! protein stabilization GO:0050821 39 22 0,000 0,01882793 0,0275883 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01967559 0,02881283 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01967559 0,0287953 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01967559 0,0287778 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01967559 0,02876031 ! gluconeogenesis GO:0006094 33 23 0,000 0,01967559 0,02874285 ! viral genome replication GO:0019079 41 23 0,000 0,01967559 0,02872541 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01967559 0,02870799 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01967559 0,02869059 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01967559 0,02867321 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01967559 0,02865586 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01967559 0,02863852 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01967559 0,02862121 ! visual behavior GO:0007632 42 23 0,000 0,01967559 0,02860391 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01967559 0,02858664 ! response to ethanol GO:0045471 46 23 0,000 0,01967559 0,02856939 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01967559 0,02855216 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01967559 0,02853494 ! peroxisome organization GO:0007031 37 23 0,000 0,01967559 0,02851776 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01967559 0,02850059 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01967559 0,02848344 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01967559 0,02846631 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01967559 0,0284492 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01967559 0,02843212 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01967559 0,02841505 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01967559 0,028398 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01967559 0,02838098 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01967559 0,02836397 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01967559 0,02834699 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01967559 0,02833003 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01967559 0,02831308 ! fatty acid transport GO:0015908 44 23 0,000 0,01967559 0,02829616 ! platelet activation GO:0030168 37 23 0,000 0,01967559 0,02827926 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01967559 0,02826237 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01967559 0,02824551 ! hormone transport GO:0009914 40 23 0,000 0,01967559 0,02822867 ! cell-cell recognition GO:0009988 25 23 0,000 0,01967559 0,02821184 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01967559 0,02819504 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01967559 0,02817826 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01967559 0,0281615 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01967559 0,02814475 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01967559 0,02812803 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02052255 0,02932141 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,02052255 0,02930401 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02052255 0,02928663 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02052255 0,02926927 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02052255 0,02925193 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02052255 0,02923461 ! vesicle docking GO:0048278 47 24 0,000 0,02052255 0,02921731 ! spinal cord development GO:0021510 47 24 0,000 0,02052255 0,02920004 ! vacuole organization GO:0007033 43 24 0,000 0,02052255 0,02918278 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02052255 0,02916554 ! digestive system process GO:0022600 39 24 0,000 0,02052255 0,02914832 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02052255 0,02913113 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02052255 0,02911395 ! regulation of behavior GO:0050795 43 24 0,000 0,02052255 0,02909679 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02052255 0,02907966 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02052255 0,02906254 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02052255 0,02904545 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,02052255 0,02902837 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02052255 0,02901132 ! membrane depolarization GO:0051899 39 24 0,000 0,02052255 0,02899428 ! pallium development GO:0021543 49 24 0,000 0,02052255 0,02897727 ! pentose metabolic process GO:0019321 35 24 0,000 0,02052255 0,02896027 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02052255 0,02894329 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02052255 0,02892634 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02052255 0,0289094 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02052255 0,02889249 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02052255 0,02887559 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02052255 0,02885871 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02052255 0,02884186 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02052255 0,02882502 ! regulation of amine transport GO:0051952 40 24 0,000 0,02052255 0,0288082 ! protein tetramerization GO:0051262 52 24 0,000 0,02052255 0,02879141 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02136881 0,02996116 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,02136881 0,02994371 ! myelination GO:0042552 45 25 0,000 0,02136881 0,02992628 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02136881 0,02990887 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02136881 0,02989149 ! phototransduction GO:0007602 33 25 0,000 0,02136881 0,02987412 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02136881 0,02985677 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02136881 0,02983944 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02136881 0,02982213 ! sperm motility GO:0030317 31 25 0,000 0,02136881 0,02980484 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02136881 0,02978758 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02136881 0,02977033 ! receptor metabolic process GO:0043112 46 25 0,000 0,02136881 0,0297531 ! chromosome condensation GO:0030261 45 25 0,000 0,02136881 0,02973589 ! response to starvation GO:0042594 42 25 0,000 0,02136881 0,0297187 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02136881 0,02970153 ! neural crest cell development GO:0014032 54 25 0,000 0,02136881 0,02968439 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02136881 0,02966726 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02136881 0,02965015 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02136881 0,02963306 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02136881 0,02961599 ! interaction with host GO:0051701 62 25 0,000 0,02136881 0,02959894 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02136881 0,02958191 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02136881 0,0295649 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02136881 0,02954791 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02136881 0,02953093 ! immunoglobulin production GO:0002377 55 25 0,000 0,02136881 0,02951398 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02136881 0,02949705 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02136881 0,02948013 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02136881 0,02946324 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02136881 0,02944637 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02136881 0,02942951 ! telomere organization GO:0032200 43 25 0,000 0,02136881 0,02941267 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02136881 0,02939586 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02136881 0,02937906 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02221436 0,03052413 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02221436 0,03050671 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02221436 0,03048931 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02221436 0,03047193 ! initiation of viral infection GO:0019059 57 26 0,000 0,02221436 0,03045456 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02221436 0,03043722 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02221436 0,0304199 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02221436 0,03040259 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02221436 0,03038531 ! molting cycle process GO:0022404 50 26 0,000 0,02221436 0,03036804 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02221436 0,0303508 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02221436 0,03033357 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02221436 0,03031637 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02221436 0,03029918 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02221436 0,03028202 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02221436 0,03026487 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02221436 0,03024774 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02221436 0,03023063 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,02221436 0,03021354 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02221436 0,03019647 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02221436 0,03017942 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02221436 0,03016239 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02221436 0,03014538 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02221436 0,03012839 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02221436 0,03011141 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02221436 0,03009446 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02221436 0,03007752 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02221436 0,03006061 ! blastocyst development GO:0001824 49 26 0,000 0,02221436 0,03004371 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02221436 0,03002683 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02221436 0,03000997 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02221436 0,02999313 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,02305921 0,03111636 ! neuron fate commitment GO:0048663 48 27 0,000 0,02305921 0,03109892 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02305921 0,0310815 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02305921 0,03106409 ! iron ion transport GO:0006826 59 27 0,000 0,02305921 0,03104671 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02305921 0,03102935 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02305921 0,031012 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02305921 0,03099468 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02305921 0,03097737 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02305921 0,03096008 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02305921 0,03094282 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02305921 0,03092557 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02305921 0,03090834 ! autophagy GO:0006914 41 27 0,000 0,02305921 0,03089113 ! male gonad development GO:0008584 44 27 0,000 0,02305921 0,03087394 ! response to toxin GO:0009636 47 27 0,000 0,02305921 0,03085677 ! primary neural tube formation GO:0014020 51 27 0,000 0,02305921 0,03083962 ! base-excision repair GO:0006284 41 27 0,000 0,02305921 0,03082248 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02305921 0,03080537 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02305921 0,03078827 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02305921 0,0307712 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02305921 0,03075414 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02305921 0,0307371 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02305921 0,03072008 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02305921 0,03070308 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02305921 0,0306861 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02390336 0,03179187 ! circadian rhythm GO:0007623 50 28 0,000 0,02390336 0,03177431 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02390336 0,03175676 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02390336 0,03173924 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02390336 0,03172173 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02390336 0,03170424 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02390336 0,03168677 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02390336 0,03166933 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02390336 0,0316519 ! synaptogenesis GO:0007416 42 28 0,000 0,02390336 0,03163449 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02390336 0,03161709 ! lipid oxidation GO:0034440 43 28 0,000 0,02390336 0,03159972 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02390336 0,03158237 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02390336 0,03156504 ! translational initiation GO:0006413 65 29 0,000 0,02474681 0,03266091 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02474681 0,032643 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02474681 0,03262511 ! regulation of pH GO:0006885 43 29 0,000 0,02474681 0,03260725 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02474681 0,0325894 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02474681 0,03257157 ! catechol metabolic process GO:0009712 54 29 0,000 0,02474681 0,03255376 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02474681 0,03253597 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02474681 0,0325182 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02474681 0,03250045 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02474681 0,03248272 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02474681 0,03246501 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02474681 0,03244732 ! cell fate determination GO:0001709 60 29 0,000 0,02474681 0,03242965 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02474681 0,03241199 ! detection of light stimulus GO:0009583 38 29 0,000 0,02474681 0,03239436 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,02474681 0,03237674 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02474681 0,03235915 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02474681 0,03234157 ! tissue homeostasis GO:0001894 48 29 0,000 0,02474681 0,03232401 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02474681 0,03230647 ! phenol metabolic process GO:0018958 55 30 0,000 0,02558956 0,03338855 ! zinc ion transport GO:0006829 45 30 0,000 0,02558956 0,03337045 ! membrane docking GO:0022406 61 30 0,000 0,02558956 0,03335237 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02558956 0,03333432 ! cell junction assembly GO:0034329 78 30 0,000 0,02558956 0,03331628 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02558956 0,03329826 ! acute-phase response GO:0006953 49 30 0,000 0,02558956 0,03328026 ! myofibril assembly GO:0030239 47 30 0,000 0,02558956 0,03326228 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02558956 0,03324432 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02558956 0,03322638 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02558956 0,03320846 ! phospholipid transport GO:0015914 51 30 0,000 0,02558956 0,03319056 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02558956 0,03317267 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02558956 0,03315481 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02558956 0,03313697 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02558956 0,03311914 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02558956 0,03310133 ! eye morphogenesis GO:0048592 60 30 0,000 0,02558956 0,03308355 ! regulation of B cell activation GO:0050864 50 30 0,000 0,02558956 0,03306578 ! response to heat GO:0009408 50 30 0,000 0,02558956 0,03304803 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02643161 0,03411719 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02643161 0,0340989 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02643161 0,03408063 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02643161 0,03406237 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02643161 0,03404414 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02643161 0,03402592 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02643161 0,03400773 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02643161 0,03398955 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02643161 0,03397139 ! ovulation cycle process GO:0022602 49 31 0,000 0,02643161 0,03395326 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02643161 0,03393514 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02643161 0,03391704 ! peptide transport GO:0015833 55 31 0,000 0,02643161 0,03389896 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02643161 0,0338809 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02643161 0,03386286 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02643161 0,03384484 ! mesoderm formation GO:0001707 69 31 0,000 0,02643161 0,03382683 ! natural killer cell activation GO:0030101 45 31 0,000 0,02643161 0,03380885 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02643161 0,03379089 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02643161 0,03377294 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02643161 0,03375501 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02643161 0,03373711 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02643161 0,03371922 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02727295 0,0347741 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02727295 0,03475568 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02727295 0,03473728 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02727295 0,0347189 ! cholesterol transport GO:0030301 56 32 0,000 0,02727295 0,03470054 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02727295 0,0346822 ! spliceosome assembly GO:0000245 67 32 0,000 0,02727295 0,03466388 ! spindle organization GO:0007051 46 32 0,000 0,02727295 0,03464558 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02727295 0,0346273 ! metanephros development GO:0001656 74 32 0,000 0,02727295 0,03460903 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02727295 0,03459079 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02727295 0,03457257 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02727295 0,03455436 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02727295 0,03453617 ! muscle cell development GO:0055001 49 32 0,000 0,02727295 0,03451801 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02727295 0,03449986 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02727295 0,03448173 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02727295 0,03446362 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02727295 0,03444553 ! ovulation cycle GO:0042698 51 32 0,000 0,02727295 0,03442745 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02727295 0,0344094 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02727295 0,03439137 ! hindbrain development GO:0030902 61 32 0,000 0,02727295 0,03437335 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02727295 0,03435536 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02727295 0,03433738 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02727295 0,03431942 ! gene silencing GO:0016458 65 32 0,000 0,02727295 0,03430148 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0281136 0,0353403 ! post-embryonic development GO:0009791 69 33 0,000 0,0281136 0,03532184 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0281136 0,03530341 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0281136 0,03528499 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0281136 0,03526659 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0281136 0,03524822 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0281136 0,03522986 ! cell fate specification GO:0001708 52 33 0,000 0,0281136 0,03521152 ! sterol transport GO:0015918 57 33 0,000 0,0281136 0,0351932 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0281136 0,0351749 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0281136 0,03515662 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0281136 0,03513835 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0281136 0,03512011 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0281136 0,03510188 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02895355 0,03613187 ! glial cell differentiation GO:0010001 63 34 0,000 0,02895355 0,03611314 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02895355 0,03609443 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02895355 0,03607574 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02895355 0,03605706 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02895355 0,03603841 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02895355 0,03601978 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02895355 0,03600116 ! mismatch repair GO:0006298 46 34 0,000 0,02895355 0,03598257 ! spermatid development GO:0007286 63 34 0,000 0,02895355 0,03596399 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02895355 0,03594543 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02895355 0,03592689 ! placenta development GO:0001890 53 34 0,000 0,02895355 0,03590837 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02895355 0,03588987 ! regulation of muscle development GO:0048634 70 35 0,000 0,0297928 0,03691117 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0297928 0,03689217 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0297928 0,03687319 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0297928 0,03685423 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0297928 0,0368353 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0297928 0,03681638 ! odontogenesis GO:0042476 66 35 0,000 0,0297928 0,03679748 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0297928 0,0367786 ! female gonad development GO:0008585 58 35 0,000 0,0297928 0,03675974 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0297928 0,0367409 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0297928 0,03672207 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0297928 0,03670327 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0297928 0,03668449 ! cytokine production GO:0001816 59 35 0,000 0,0297928 0,03666572 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0297928 0,03664698 ! neural tube formation GO:0001841 67 35 0,000 0,0297928 0,03662825 ! vesicle localization GO:0051648 64 35 0,000 0,0297928 0,03660954 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03063136 0,03762075 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03063136 0,03760156 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03063136 0,03758238 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03063136 0,03756323 ! cell junction organization GO:0034330 86 36 0,000 0,03063136 0,03754409 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03063136 0,03752497 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03063136 0,03750588 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03063136 0,0374868 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03063136 0,03746774 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03063136 0,0374487 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03063136 0,03742968 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03063136 0,03741068 ! aerobic respiration GO:0009060 55 36 0,000 0,03063136 0,0373917 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03063136 0,03737274 ! embryonic organ development GO:0048568 57 36 0,000 0,03063136 0,0373538 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03063136 0,03733488 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03063136 0,03731597 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03146922 0,03831727 ! meiosis I GO:0007127 65 37 0,000 0,03146922 0,03829789 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03146922 0,03827853 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03146922 0,03825919 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03146922 0,03823987 ! organic anion transport GO:0015711 68 37 0,000 0,03146922 0,03822056 ! tissue remodeling GO:0048771 76 37 0,000 0,03146922 0,03820128 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03146922 0,03818201 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03146922 0,03816277 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03146922 0,03814354 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03146922 0,03812434 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03146922 0,03810515 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03146922 0,03808598 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03146922 0,03806683 ! pigment metabolic process GO:0042440 80 37 0,000 0,03146922 0,0380477 ! spermatid differentiation GO:0048515 66 37 0,000 0,03146922 0,0380286 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03146922 0,0380095 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03230638 0,03900107 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03230638 0,03898152 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03230638 0,03896198 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03230638 0,03894246 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03230638 0,03892296 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03230638 0,03890347 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03230638 0,03888401 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03230638 0,03886457 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03230638 0,03884515 ! lipid homeostasis GO:0055088 67 38 0,000 0,03230638 0,03882575 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03230638 0,03880636 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03230638 0,038787 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03230638 0,03876765 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03230638 0,03874833 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,03230638 0,03872902 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03230638 0,03870973 ! glucan metabolic process GO:0044042 62 38 0,000 0,03230638 0,03869046 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 0,000 0,03314284 0,03967248 ! learning GO:0007612 77 39 0,000 0,03314284 0,03965275 ! ear morphogenesis GO:0042471 60 39 0,000 0,03314284 0,03963304 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03314284 0,03961335 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03314284 0,03959368 ! segmentation GO:0035282 67 39 0,000 0,03314284 0,03957403 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03314284 0,0395544 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03314284 0,03953479 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03314284 0,0395152 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03314284 0,03949563 ! RNA modification GO:0009451 57 39 0,000 0,03314284 0,03947608 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03314284 0,03945654 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03397861 0,04043152 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03397861 0,04041154 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03397861 0,04039157 ! feeding behavior GO:0007631 59 40 0,000 0,03397861 0,04037162 ! negative regulation of binding GO:0051100 72 40 0,000 0,03397861 0,0403517 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03397861 0,04033179 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03397861 0,0403119 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03397861 0,04029204 ! maintenance of protein location GO:0045185 91 40 0,000 0,03397861 0,04027219 ! cytokinesis GO:0000910 72 40 0,000 0,03397861 0,04025236 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03481369 0,04122132 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03481369 0,04120105 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03481369 0,04118079 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03481369 0,04116056 ! gliogenesis GO:0042063 88 41 0,000 0,03481369 0,04114034 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03481369 0,04112014 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03481369 0,04109997 ! T cell differentiation GO:0030217 81 41 0,000 0,03481369 0,04107981 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,03481369 0,04105967 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03481369 0,04103955 ! female gamete generation GO:0007292 61 41 0,000 0,03481369 0,04101946 ! polyol metabolic process GO:0019751 66 41 0,000 0,03481369 0,04099938 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03481369 0,04097932 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03564807 0,04194095 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03564807 0,04192046 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03564807 0,04189998 ! regulation of tube size GO:0035150 71 42 0,000 0,03564807 0,04187952 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03564807 0,04185908 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03564807 0,04183866 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03564807 0,04181826 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03564807 0,04179788 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03564807 0,04177752 ! neuron migration GO:0001764 79 42 0,000 0,03564807 0,04175718 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03564807 0,04173686 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03564807 0,04171656 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03648176 0,04267142 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03648176 0,04265068 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03648176 0,04262997 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03648176 0,04260927 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03648176 0,0425886 ! glucose transport GO:0015758 65 43 0,000 0,03648176 0,04256795 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03648176 0,04254731 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03648176 0,0425267 ! neural tube development GO:0021915 77 43 0,000 0,03648176 0,0425061 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03648176 0,04248553 ! striated muscle contraction GO:0006941 77 43 0,000 0,03648176 0,04246497 ! phagocytosis GO:0006909 90 43 0,000 0,03648176 0,04244444 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03648176 0,04242393 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03731475 0,04337164 ! hexose transport GO:0008645 67 44 0,000 0,03731475 0,04335069 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03731475 0,04332977 ! male sex differentiation GO:0046661 76 44 0,000 0,03731475 0,04330887 ! double-strand break repair GO:0006302 81 44 0,000 0,03731475 0,04328799 ! biopolymer methylation GO:0043414 84 44 0,000 0,03731475 0,04326713 ! B cell differentiation GO:0030183 107 44 0,000 0,03731475 0,04324628 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03731475 0,04322546 ! developmental growth GO:0048589 82 44 0,000 0,03731475 0,04320466 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03731475 0,04318388 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03814705 0,04412587 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03814705 0,04410466 ! leukocyte migration GO:0050900 68 45 0,000 0,03814705 0,04408348 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03814705 0,04406232 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03814705 0,04404117 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,03814705 0,04402005 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03814705 0,04399895 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03814705 0,04397787 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03814705 0,0439568 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03814705 0,04393576 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03814705 0,04391474 ! cell growth GO:0016049 84 45 0,000 0,03814705 0,04389374 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03897866 0,04482919 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03897866 0,04480777 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03897866 0,04478637 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03897866 0,04476499 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,03897866 0,04474364 ! pigmentation GO:0043473 100 46 0,000 0,03897866 0,0447223 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03897866 0,04470098 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03980958 0,04563213 ! endosome transport GO:0016197 108 47 0,000 0,03980958 0,0456104 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03980958 0,0455887 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03980958 0,04556701 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03980958 0,04554534 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03980958 0,04552369 ! JNK cascade GO:0007254 91 47 0,000 0,03980958 0,04550207 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03980958 0,04548046 ! methylation GO:0032259 90 47 0,000 0,03980958 0,04545888 ! protein homooligomerization GO:0051260 76 47 0,000 0,03980958 0,04543731 ! mitochondrial transport GO:0006839 82 48 0,000 0,04063981 0,04636291 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04063981 0,04634094 ! cellular component disassembly GO:0022411 86 48 0,000 0,04063981 0,04631899 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04063981 0,04629705 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04063981 0,04627514 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04063981 0,04625325 ! activation of caspase activity GO:0006919 84 48 0,000 0,04063981 0,04623138 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04063981 0,04620954 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04063981 0,04618771 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04063981 0,0461659 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,04063981 0,04614411 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04146935 0,0470638 ! regulation of action potential GO:0001508 95 49 0,000 0,04146935 0,04704161 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04146935 0,04701944 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04146935 0,04699729 ! regulation of ion transport GO:0043269 77 49 0,000 0,04146935 0,04697516 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04146935 0,04695306 ! peptide metabolic process GO:0006518 76 49 0,000 0,04146935 0,04693097 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04146935 0,04690891 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04146935 0,04688686 ! endocrine system development GO:0035270 104 49 0,000 0,04146935 0,04686484 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04146935 0,04684284 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04146935 0,04682086 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04146935 0,0467989 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04229819 0,04771189 ! neuromuscular process GO:0050905 99 50 0,000 0,04229819 0,04768953 ! regulation of ossification GO:0030278 117 50 0,000 0,04229819 0,04766719 ! inner ear development GO:0048839 79 50 0,000 0,04229819 0,04764488 ! histone modification GO:0016570 91 50 0,000 0,04229819 0,04762258 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04229819 0,04760031 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04229819 0,04757805 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04229819 0,04755582 ! positive regulation of binding GO:0051099 78 51 0,000 0,04312635 0,04846427 ! viral infectious cycle GO:0019058 99 51 0,000 0,04312635 0,04844164 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04312635 0,04841904 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04312635 0,04839646 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04312635 0,04837389 ! excretion GO:0007588 83 51 0,000 0,04312635 0,04835135 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04312635 0,04832883 ! chromatin remodeling GO:0006338 109 51 0,000 0,04312635 0,04830633 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04312635 0,04828385 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04312635 0,0482614 ! vesicle organization GO:0016050 107 51 0,000 0,04312635 0,04823896 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,04312635 0,04821654 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,04312635 0,04819415 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04312635 0,04817177 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04395382 0,04907327 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04395382 0,04905051 ! membrane fusion GO:0006944 110 52 0,000 0,04395382 0,04902777 ! positive regulation of growth GO:0045927 90 52 0,000 0,04395382 0,04900505 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04395382 0,04898235 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04395382 0,04895967 ! amino acid activation GO:0043038 92 52 0,000 0,04395382 0,04893702 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,04395382 0,04891438 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0447806 0,04981143 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0447806 0,04978842 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0447806 0,04976542 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0447806 0,04974244 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0447806 0,04971949 ! cell maturation GO:0048469 100 53 0,000 0,0447806 0,04969656 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0447806 0,04967364 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0447806 0,04965075 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0456067 0,0505434 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0456067 0,05052013 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0456067 0,05049688 ! cell recognition GO:0008037 85 54 0,000 0,0456067 0,05047365 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0456067 0,05045044 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0456067 0,05042726 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0456067 0,0504041 ! chloride transport GO:0006821 90 55 0,000 0,04643211 0,05129277 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04643211 0,05126923 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04643211 0,05124571 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04643211 0,05122221 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04643211 0,05119874 ! aging GO:0007568 103 55 0,000 0,04643211 0,05117529 ! gastrulation GO:0007369 112 55 0,000 0,04643211 0,05115185 ! heart morphogenesis GO:0003007 97 55 0,000 0,04643211 0,05112844 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04643211 0,05110505 ! RNA elongation GO:0006354 79 55 0,000 0,04643211 0,05108169 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04643211 0,05105834 ! regulation of actin filament length GO:0030832 105 56 0,000 0,04725683 0,05194149 ! sensory perception of smell GO:0007608 80 56 0,000 0,04725683 0,05191777 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,04725683 0,05189408 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,04725683 0,0518704 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,04725683 0,05184675 ! regulation of DNA replication GO:0006275 101 56 0,000 0,04725683 0,05182312 ! proton transport GO:0015992 94 56 0,000 0,04725683 0,05179951 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,04725683 0,05177592 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04808086 0,05265478 ! muscle fiber development GO:0048747 112 57 0,000 0,04808086 0,05263083 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04808086 0,05260689 ! lipid modification GO:0030258 97 57 0,000 0,04808086 0,05258298 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04808086 0,05255909 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04808086 0,05253522 ! maintenance of location GO:0051235 118 57 0,000 0,04808086 0,05251137 ! hydrogen transport GO:0006818 97 58 0,000 0,04890421 0,05338636 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04890421 0,05336215 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04890421 0,05333796 ! adult behavior GO:0030534 99 58 0,000 0,04890421 0,05331379 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04890421 0,05328964 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04972688 0,05416155 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04972688 0,05413704 ! DNA catabolic process GO:0006308 86 59 0,000 0,04972688 0,05411256 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04972688 0,0540881 ! establishment of organelle localization GO:0051656 109 59 0,000 0,04972688 0,05406365 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05054886 0,0549325 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,05054886 0,0549077 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05054886 0,05488292 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05054886 0,05485817 ! camera-type eye development GO:0043010 116 60 0,000 0,05054886 0,05483343 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05054886 0,05480872 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05054886 0,05478403 ! kidney development GO:0001822 122 60 0,000 0,05054886 0,05475937 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,05137016 0,05562403 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,05137016 0,05559901 ! mesoderm development GO:0007498 119 61 0,000 0,05137016 0,05557401 ! tRNA processing GO:0008033 89 61 0,000 0,05137016 0,05554903 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,05137016 0,05552408 ! ear development GO:0043583 103 62 0,000 0,05219077 0,05638572 ! viral reproductive process GO:0022415 126 62 0,000 0,05219077 0,05636041 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05219077 0,05633512 ! gonad development GO:0008406 98 62 0,000 0,05219077 0,05630986 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05219077 0,05628462 ! regulation of mitosis GO:0007088 105 63 0,000 0,0530107 0,05714326 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,0530107 0,05711767 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,0530107 0,0570921 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,0530107 0,05706655 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,0530107 0,05704103 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05382995 0,05789667 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05382995 0,0578708 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05382995 0,05784496 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05382995 0,05781913 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05382995 0,05779333 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05382995 0,05776756 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05464852 0,05861986 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05464852 0,05859373 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05464852 0,05856763 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05464852 0,05854156 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05464852 0,0585155 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05546641 0,05936484 ! actin filament organization GO:0007015 148 66 0,000 0,05546641 0,05933845 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05546641 0,05931208 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05546641 0,05928573 ! secondary metabolic process GO:0019748 116 66 0,000 0,05546641 0,0592594 ! developmental maturation GO:0021700 116 66 0,000 0,05546641 0,0592331 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,05628361 0,06007913 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05628361 0,06005249 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,05628361 0,06002587 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,05628361 0,05999928 ! activation of MAPK activity GO:0000187 115 67 0,000 0,05628361 0,05997271 ! lung development GO:0030324 144 67 0,000 0,05628361 0,05994616 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05628361 0,05991963 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05628361 0,05989313 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05628361 0,05986665 ! adaptive immune response GO:0002250 119 67 0,000 0,05628361 0,0598402 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05628361 0,05981377 ! amino acid transport GO:0006865 125 68 0,000 0,05710014 0,06065472 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,05710014 0,06062795 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05710014 0,06060121 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05710014 0,06057449 ! viral reproduction GO:0016032 134 68 0,000 0,05710014 0,06054779 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05710014 0,06052112 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05710014 0,06049447 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05791599 0,06133181 ! negative regulation of cell size GO:0045792 134 69 0,000 0,05791599 0,06130482 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05791599 0,06127786 ! urogenital system development GO:0001655 137 69 0,000 0,05791599 0,06125093 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05791599 0,06122402 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05791599 0,06119713 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05791599 0,06117026 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05873115 0,06200402 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05873115 0,06197682 ! amine catabolic process GO:0009310 117 71 0,000 0,05954564 0,06280878 ! reproductive structure development GO:0048608 113 71 0,000 0,05954564 0,06278125 ! appendage development GO:0048736 136 71 0,000 0,05954564 0,06275375 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05954564 0,06272628 ! B cell activation GO:0042113 160 71 0,000 0,05954564 0,06269883 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05954564 0,0626714 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05954564 0,062644 ! acute inflammatory response GO:0002526 113 72 0,000 0,06035946 0,0634724 ! regulation of caspase activity GO:0043281 122 72 0,000 0,06035946 0,06344467 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06035946 0,06341697 ! carbohydrate transport GO:0008643 110 72 0,000 0,06035946 0,06338929 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,06035946 0,06336163 ! respiratory system development GO:0060541 153 72 0,000 0,06035946 0,063334 ! learning or memory GO:0007611 147 73 0,000 0,06117259 0,06415922 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06117259 0,06413127 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06117259 0,06410334 ! fertilization GO:0009566 90 73 0,000 0,06117259 0,06407543 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06198505 0,06489819 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06198505 0,06486996 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06198505 0,06484175 ! meiosis GO:0007126 121 74 0,000 0,06198505 0,06481357 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,06198505 0,06478542 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,06198505 0,06475729 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,06198505 0,06472918 ! eye development GO:0001654 143 74 0,000 0,06198505 0,0647011 ! organelle localization GO:0051640 136 74 0,000 0,06198505 0,06467304 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06279683 0,06549163 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,06279683 0,06546325 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06279683 0,0654349 ! meiotic cell cycle GO:0051321 122 75 0,000 0,06279683 0,06540657 ! rhythmic process GO:0048511 128 75 0,000 0,06279683 0,06537827 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06279683 0,06534999 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06360794 0,06616546 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06360794 0,06613687 ! defense response to bacterium GO:0042742 89 76 0,000 0,06360794 0,0661083 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06360794 0,06607975 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,06441837 0,0668928 ! blood coagulation GO:0007596 146 78 0,000 0,06522813 0,06770444 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06522813 0,06767524 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,06522813 0,06764607 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,06522813 0,06761693 ! protein oligomerization GO:0051259 139 78 0,000 0,06522813 0,06758781 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06603722 0,0683967 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06603722 0,06836727 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06603722 0,06833787 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,06603722 0,06830849 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06603722 0,06827913 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06684563 0,0690853 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06684563 0,06905564 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06684563 0,069026 ! protein import into nucleus GO:0006606 158 80 0,000 0,06684563 0,06899639 ! T cell activation GO:0042110 168 81 0,000 0,06765336 0,06980017 ! response to hypoxia GO:0001666 171 81 0,000 0,06765336 0,06977025 ! digestion GO:0007586 112 81 0,000 0,06765336 0,06974036 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06765336 0,06971049 ! nuclear import GO:0051170 161 81 0,000 0,06765336 0,06968065 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06765336 0,06965083 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06846043 0,07045158 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06846043 0,07042146 ! response to drug GO:0042493 143 82 0,000 0,06846043 0,07039136 ! response to nutrient GO:0007584 125 82 0,000 0,06846043 0,07036129 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06846043 0,07033125 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06846043 0,07030123 ! response to oxygen levels GO:0070482 176 83 0,000 0,06926682 0,07109896 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06926682 0,07106865 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07007254 0,07186468 ! hemostasis GO:0007599 158 84 0,000 0,07007254 0,07183406 ! negative regulation of transport GO:0051051 153 84 0,000 0,07007254 0,07180347 ! negative regulation of growth GO:0045926 155 84 0,000 0,07007254 0,0717729 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07007254 0,07174236 ! nucleosome assembly GO:0006334 122 85 0,000 0,0708776 0,07253573 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0708776 0,07250489 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,0708776 0,07247407 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,07168198 0,07326544 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07168198 0,07323433 ! chromatin assembly GO:0031497 124 86 0,000 0,07168198 0,07320324 ! tube morphogenesis GO:0035239 176 86 0,000 0,07168198 0,07317218 ! mitochondrion organization GO:0007005 148 86 0,000 0,07168198 0,07314115 ! amine transport GO:0015837 155 86 0,000 0,07168198 0,07311015 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07248569 0,07389855 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07248569 0,07386725 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07248569 0,07383597 ! regulation of protein transport GO:0051223 154 87 0,000 0,07248569 0,07380473 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,07328873 0,07459082 ! regulation of DNA binding GO:0051101 155 88 0,000 0,07328873 0,07455928 ! gland development GO:0048732 206 88 0,000 0,07328873 0,07452776 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07328873 0,07449628 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07328873 0,07446482 ! cellular defense response GO:0006968 114 89 0,000 0,07409111 0,07524829 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07409111 0,07521654 ! ossification GO:0001503 188 90 0,000 0,07489281 0,07599836 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07489281 0,07596632 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,07489281 0,0759343 ! sex differentiation GO:0007548 145 90 0,000 0,07489281 0,07590232 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07489281 0,07587036 ! bone development GO:0060348 189 91 0,000 0,07569385 0,07664958 ! sterol metabolic process GO:0016125 152 91 0,000 0,07569385 0,07661733 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,07569385 0,07658512 ! regulation of defense response GO:0031347 149 92 0,000 0,07649422 0,07736238 ! nucleosome organization GO:0034728 138 92 0,000 0,07649422 0,07732987 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07649422 0,0772974 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07649422 0,07726494 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,07729393 0,07803995 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,07729393 0,07800721 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,07729393 0,0779745 ! regulation of membrane potential GO:0042391 164 93 0,000 0,07729393 0,07794182 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,07729393 0,07790917 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,07809297 0,07868161 ! female pregnancy GO:0007565 164 94 0,000 0,07809297 0,07864867 ! transcription initiation GO:0006352 153 94 0,000 0,07809297 0,07861576 ! regulation of T cell activation GO:0050863 158 94 0,000 0,07809297 0,07858289 ! forebrain development GO:0030900 188 95 0,000 0,07889134 0,07935308 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07968905 0,08012196 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07968905 0,08008849 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07968905 0,08005505 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07968905 0,08002164 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,08048609 0,0807883 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,08048609 0,08075461 ! protein ubiquitination GO:0016567 217 97 0,000 0,08048609 0,08072094 ! hormone metabolic process GO:0042445 157 97 0,000 0,08048609 0,08068731 ! regulation of protein localization GO:0032880 176 97 0,000 0,08048609 0,0806537 ! response to virus GO:0009615 160 98 0,000 0,08128248 0,08141783 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08128248 0,08138395 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08128248 0,0813501 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08207819 0,08211232 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,08207819 0,08207819 GO:0060538|skeletal muscle organ development,