pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5717-7-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of Ras GTPase activity GO:0032318 84 80 3,000 7,739E-07 2,764E-03 ! Ras GTPase activator activity GO:0005099 89 84 3,000 9,421E-07 1,682E-03 ! regulation of GTPase activity GO:0043087 104 97 3,000 1,68E-06 1,999E-03 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 2,000 2,731E-06 2,438E-03 ! regulation of Rab protein signal transduction GO:0032483 41 40 2,000 6,609E-06 4,72E-03 GO:0032313|regulation of Rab GTPase activity, ! inorganic anion transmembrane transporter activity GO:0015103 42 40 2,000 6,609E-06 3,933E-03 ! Rab GTPase activator activity GO:0005097 42 41 2,000 7,127E-06 3,636E-03 ! glycolysis GO:0006096 42 42 2,000 7,671E-06 3,424E-03 ! negative regulation of protein ubiquitination GO:0031397 5 5 1,000 8,371E-06 3,321E-03 ! substrate-bound cell migration, cell extension GO:0006930 5 5 1,000 8,371E-06 2,989E-03 ! proteasome complex GO:0000502 48 47 2,000 1,08E-05 3,507E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,255E-05 3,734E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 1,000 1,255E-05 3,447E-03 ! nuclear origin of replication recognition complex GO:0005664 6 6 1,000 1,255E-05 3,201E-03 GO:0000808|origin recognition complex, ! glucose catabolic process GO:0006007 52 52 2,000 1,468E-05 3,496E-03 ! proteasome regulatory particle GO:0005838 8 7 1,000 1,756E-05 3,919E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 1,000 1,756E-05 3,688E-03 GO:0010921|regulation of phosphatase activity, ! regulation of focal adhesion formation GO:0051893 9 7 1,000 1,756E-05 3,484E-03 ! centriolar satellite GO:0034451 8 7 1,000 1,756E-05 3,3E-03 ! sodium:phosphate symporter activity GO:0005436 7 7 1,000 1,756E-05 3,135E-03 ! chromosome segregation GO:0007059 59 57 2,000 1,939E-05 3,297E-03 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 2,34E-05 3,798E-03 ! phosphate transport GO:0006817 9 8 1,000 2,34E-05 3,633E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 2,000 2,379E-05 3,54E-03 ! hexose catabolic process GO:0019320 63 62 2,000 2,499E-05 3,569E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 2,000 2,499E-05 3,432E-03 ! negative regulation of ligase activity GO:0051352 64 63 2,000 2,622E-05 3,468E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 2,000 2,75E-05 3,507E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 2,000 2,881E-05 3,548E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 9 1,000 3,007E-05 3,579E-03 ! response to unfolded protein GO:0006986 68 66 2,000 3,017E-05 3,475E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 2,000 3,156E-05 3,522E-03 ! positive regulation of ligase activity GO:0051351 71 69 2,000 3,448E-05 3,731E-03 ! regulation of dephosphorylation GO:0035303 12 10 1,000 3,757E-05 3,945E-03 ! detection of mechanical stimulus GO:0050982 10 10 1,000 3,757E-05 3,833E-03 ! regulation of stress fiber formation GO:0051492 13 10 1,000 3,757E-05 3,726E-03 ! proteasome accessory complex GO:0022624 11 10 1,000 3,757E-05 3,626E-03 ! monosaccharide catabolic process GO:0046365 72 71 2,000 3,757E-05 3,531E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 2,000 3,919E-05 3,588E-03 ! response to protein stimulus GO:0051789 74 72 2,000 3,919E-05 3,498E-03 ! cellular carbohydrate catabolic process GO:0044275 75 74 2,000 4,254E-05 3,705E-03 ! regulation of actin filament bundle formation GO:0032231 14 11 1,000 4,589E-05 3,902E-03 ! substrate-bound cell migration GO:0006929 11 11 1,000 4,589E-05 3,811E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 1,000 4,589E-05 3,724E-03 ! regulation of ligase activity GO:0051340 78 76 2,000 4,609E-05 3,657E-03 ! alcohol catabolic process GO:0046164 83 80 2,000 5,374E-05 4,172E-03 ! positive regulation of Ras GTPase activity GO:0032320 12 12 1,000 5,504E-05 4,182E-03 ! phosphate transmembrane transporter activity GO:0015114 13 12 1,000 5,504E-05 4,094E-03 ! SH3 domain binding GO:0017124 97 83 2,000 6E-05 4,372E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 2,000 6,218E-05 4,441E-03 GO:0010498|proteasomal protein catabolic process, ! positive regulation of GTPase activity GO:0043547 14 13 1,000 6,501E-05 4,552E-03 ! cartilage condensation GO:0001502 14 13 1,000 6,501E-05 4,464E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 6,501E-05 4,38E-03 ! inorganic anion exchanger activity GO:0005452 15 14 1,000 7,58E-05 5,013E-03 ! homophilic cell adhesion GO:0007156 93 91 2,000 7,897E-05 5,127E-03 ! carbohydrate catabolic process GO:0016052 95 94 2,000 8,699E-05 5,547E-03 ! anion exchanger activity GO:0015380 18 17 1,000 1,131E-04 7,086E-03 ! regulation of Rho GTPase activity GO:0032319 17 17 1,000 1,131E-04 6,963E-03 ! chaperone binding GO:0051087 18 18 1,000 1,272E-04 7,697E-03 ! negative regulation of translation GO:0017148 20 18 1,000 1,272E-04 7,569E-03 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 1,000 1,272E-04 7,445E-03 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 1,000 1,272E-04 7,324E-03 ! anion:anion antiporter activity GO:0015301 20 19 1,000 1,421E-04 8,052E-03 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 1,000 1,421E-04 7,926E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,421E-04 7,804E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! chloride transmembrane transporter activity GO:0015108 20 19 1,000 1,421E-04 7,686E-03 ! regulation of cell-matrix adhesion GO:0001952 22 20 1,000 1,577E-04 8,408E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 23 22 1,000 1,916E-04 0,01006086 ! negative regulation of protein modification process GO:0031400 28 24 1,000 2,287E-04 0,0118337 ! RNA export from nucleus GO:0006405 27 25 1,000 2,484E-04 0,01267208 ! actin filament GO:0005884 28 25 1,000 2,484E-04 0,0124936 ! fat cell differentiation GO:0045444 26 26 1,000 2,69E-04 0,01333951 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 2,69E-04 0,01315677 ! anion:cation symporter activity GO:0015296 28 27 1,000 2,903E-04 0,01400969 ! thyroid hormone receptor binding GO:0046966 29 28 1,000 3,125E-04 0,01487811 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 1,000 3,125E-04 0,01468235 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 3,125E-04 0,01449167 ! response to mechanical stimulus GO:0009612 28 28 1,000 3,125E-04 0,01430588 ! Rho GTPase activator activity GO:0005100 32 28 1,000 3,125E-04 0,01412479 ! NAD or NADH binding GO:0051287 31 31 1,000 3,838E-04 0,01713061 ! microtubule organizing center part GO:0044450 34 31 1,000 3,838E-04 0,01691912 ! JAK-STAT cascade GO:0007259 34 32 1,000 4,091E-04 0,0178173 ! response to calcium ion GO:0051592 39 35 1,000 4,9E-04 0,0210817 ! positive regulation of cell cycle GO:0045787 39 39 1,000 6,089E-04 0,02588586 ! keratin filament GO:0045095 41 39 1,000 6,089E-04 0,02558132 ! nuclear export GO:0051168 42 40 1,000 6,406E-04 0,02660015 ! response to insulin stimulus GO:0032868 45 40 1,000 6,406E-04 0,0262944 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 1,000 8,473E-04 0,03438201 ! cytokine-mediated signaling pathway GO:0019221 49 48 1,000 9,224E-04 0,03701018 ! detection of abiotic stimulus GO:0009582 48 48 1,000 9,224E-04 0,03659896 ! protein N-terminus binding GO:0047485 51 48 1,000 9,224E-04 0,03619677 ! lamellipodium GO:0030027 53 49 1,000 9,611E-04 0,03730662 ! response to UV GO:0009411 50 49 1,000 9,611E-04 0,03690548 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 1,000 1,001E-03 0,0380136 ! antiporter activity GO:0015297 52 51 1,000 1,041E-03 0,03912745 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 1,082E-03 0,04024682 ! cell projection assembly GO:0030031 56 53 1,000 1,124E-03 0,04137148 ! regulation of protein catabolic process GO:0042176 57 54 1,000 1,166E-03 0,04250123 ! response to peptide hormone stimulus GO:0043434 60 55 1,000 1,21E-03 0,04363586 ! cartilage development GO:0051216 59 56 1,000 1,254E-03 0,04477517 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 1,299E-03 0,045919 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 1,344E-03 0,04706715 GO:0045937|positive regulation of phosphate metabolic process, ! detection of external stimulus GO:0009581 59 58 1,000 1,344E-03 0,04661019 ! protein kinase regulator activity GO:0019887 64 64 1,000 1,634E-03 0,05611622 ! response to metal ion GO:0010038 69 65 1,000 1,685E-03 0,05731518 ! positive regulation of protein modification process GO:0031401 69 65 1,000 1,685E-03 0,05677447 ! skeletal system morphogenesis GO:0048705 66 65 1,000 1,685E-03 0,05624387 ! nuclear hormone receptor binding GO:0035257 68 67 1,000 1,789E-03 0,05916833 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 1,843E-03 0,06036927 ! axon guidance GO:0007411 74 69 1,000 1,897E-03 0,06157273 ! response to inorganic substance GO:0010035 74 70 1,000 1,951E-03 0,0627786 ! cell cortex GO:0005938 74 70 1,000 1,951E-03 0,06221807 ! cell-matrix adhesion GO:0007160 76 71 1,000 2,007E-03 0,06342052 ! regulation of actin filament-based process GO:0032970 77 71 1,000 2,007E-03 0,0628642 ! hormone receptor binding GO:0051427 75 73 1,000 2,12E-03 0,06583216 ! regulation of Rho protein signal transduction GO:0035023 79 74 1,000 2,178E-03 0,06704117 ! nuclear chromosome part GO:0044454 76 74 1,000 2,178E-03 0,06646817 ! neuropeptide signaling pathway GO:0007218 79 74 1,000 2,178E-03 0,06590488 ! regulation of catabolic process GO:0009894 80 75 1,000 2,236E-03 0,06710509 ! establishment of RNA localization GO:0051236 78 75 1,000 2,236E-03 0,06654588 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! inorganic anion transport GO:0015698 78 76 1,000 2,295E-03 0,06774282 ! cell-substrate adhesion GO:0031589 81 76 1,000 2,295E-03 0,06718756 ! cilium GO:0005929 77 76 1,000 2,295E-03 0,06664131 ! RNA localization GO:0006403 80 77 1,000 2,355E-03 0,06782985 ! kinase regulator activity GO:0019207 77 77 1,000 2,355E-03 0,06728721 ! regulation of cell adhesion GO:0030155 82 78 1,000 2,416E-03 0,06847269 ! protein kinase binding GO:0019901 89 80 1,000 2,54E-03 0,07140766 ! interphase of mitotic cell cycle GO:0051329 84 82 1,000 2,666E-03 0,07437881 GO:0051325|interphase, ! cell leading edge GO:0031252 90 83 1,000 2,73E-03 0,0755835 ! Golgi vesicle transport GO:0048193 86 86 1,000 2,928E-03 0,08042519 ! cell cycle arrest GO:0007050 92 87 1,000 2,995E-03 0,08164488 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 1,000 3,063E-03 0,08286573 ! detection of stimulus GO:0051606 90 88 1,000 3,063E-03 0,08224268 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 1,000 3,132E-03 0,08346018 ! intermediate filament GO:0005882 92 90 1,000 3,201E-03 0,08467879 ! apical plasma membrane GO:0016324 96 91 1,000 3,271E-03 0,08589846 ! intermediate filament cytoskeleton GO:0045111 93 91 1,000 3,271E-03 0,08527146 ! solute:cation symporter activity GO:0015294 95 94 1,000 3,486E-03 0,09021225 ! in utero embryonic development GO:0001701 97 95 1,000 3,559E-03 0,09143974 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 1,000 3,633E-03 0,09266796 ! nuclear chromosome GO:0000228 102 99 1,000 3,859E-03 0,09772337 ! regulation of cellular component biogenesis GO:0044087 106 99 1,000 3,859E-03 0,09703518 ! kinase binding GO:0019900 108 99 1,000 3,859E-03 0,09635661 ! tRNA transcription GO:0009304 5 5 0,000 4,743E-03 0,11760838 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 4,743E-03 0,11679729 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 4,743E-03 0,1159973 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 4,743E-03 0,11520821 ! response to oxygen radical GO:0000305 5 5 0,000 4,743E-03 0,11442977 ! positive regulation of axon extension GO:0045773 6 5 0,000 4,743E-03 0,11366179 ! negative regulation of bone resorption GO:0045779 5 5 0,000 4,743E-03 0,11290404 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 4,743E-03 0,11215633 ! regulation of interferon-beta production GO:0032648 6 5 0,000 4,743E-03 0,11141846 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 4,743E-03 0,11069024 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4,743E-03 0,10997147 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 4,743E-03 0,10926198 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 4,743E-03 0,10856158 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4,743E-03 0,1078701 ! N-terminal protein lipidation GO:0006498 5 5 0,000 4,743E-03 0,10718738 ! glycolipid transport GO:0046836 5 5 0,000 4,743E-03 0,10651325 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 4,743E-03 0,10584754 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 4,743E-03 0,1051901 ! protein amino acid sulfation GO:0006477 5 5 0,000 4,743E-03 0,10454078 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 4,743E-03 0,10389943 ! embryonic camera-type eye development GO:0031076 7 5 0,000 4,743E-03 0,10326589 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 4,743E-03 0,10264004 ! selenocysteine incorporation GO:0001514 5 5 0,000 4,743E-03 0,10202173 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 4,743E-03 0,10141082 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 4,743E-03 0,10080718 ! elastic fiber assembly GO:0048251 5 5 0,000 4,743E-03 0,10021069 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 4,743E-03 0,09962121 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 4,743E-03 0,09903863 ! ruffle membrane GO:0032587 5 5 0,000 4,743E-03 0,09846283 ! regulation of histone modification GO:0031056 5 5 0,000 4,743E-03 0,09789368 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 4,743E-03 0,09733107 ! behavioral response to pain GO:0048266 5 5 0,000 4,743E-03 0,09677489 ! clathrin coat assembly GO:0048268 6 5 0,000 4,743E-03 0,09622504 ! Notch receptor processing GO:0007220 5 5 0,000 4,743E-03 0,09568139 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 4,743E-03 0,09514386 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 4,743E-03 0,09461233 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 4,743E-03 0,0940867 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 4,743E-03 0,09356689 ! response to lipid GO:0033993 5 5 0,000 4,743E-03 0,09305278 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 4,743E-03 0,0925443 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4,743E-03 0,09204134 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 4,743E-03 0,09154382 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 4,743E-03 0,09105165 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 4,743E-03 0,09056474 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 4,743E-03 0,09008301 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4,743E-03 0,08960638 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 4,743E-03 0,08913477 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4,743E-03 0,0886681 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 4,743E-03 0,08820628 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 4,743E-03 0,08774926 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 4,743E-03 0,08729694 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4,743E-03 0,08684926 ! negative regulation of endocytosis GO:0045806 5 5 0,000 4,743E-03 0,08640616 ! microfibril GO:0001527 5 5 0,000 4,743E-03 0,08596755 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 4,743E-03 0,08553337 ! toxin metabolic process GO:0009404 5 5 0,000 4,743E-03 0,08510355 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4,743E-03 0,08467803 ! cytokine secretion GO:0050663 5 5 0,000 4,743E-03 0,08425675 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 4,743E-03 0,08383964 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4,743E-03 0,08342663 ! skeletal myofibril assembly GO:0014866 5 5 0,000 4,743E-03 0,08301768 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 4,743E-03 0,08261271 ! epithelial cell proliferation GO:0050673 5 5 0,000 4,743E-03 0,08221168 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 4,743E-03 0,08181452 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 4,743E-03 0,08142118 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 4,743E-03 0,08103161 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4,743E-03 0,08064575 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 4,743E-03 0,08026354 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 4,743E-03 0,07988494 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4,743E-03 0,07950989 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4,743E-03 0,07913835 ! glutamate catabolic process GO:0006538 6 5 0,000 4,743E-03 0,07877026 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 4,743E-03 0,07840559 ! microvillus organization GO:0032528 5 5 0,000 4,743E-03 0,07804427 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 4,743E-03 0,07768627 ! L-serine biosynthetic process GO:0006564 5 5 0,000 4,743E-03 0,07733154 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4,743E-03 0,07698003 ! pericentriolar material GO:0000242 6 5 0,000 4,743E-03 0,0766317 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,743E-03 0,07628652 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 4,743E-03 0,07594442 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 4,743E-03 0,07560539 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 4,743E-03 0,07526936 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 4,743E-03 0,07493631 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 4,743E-03 0,0746062 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 4,743E-03 0,07427898 ! response to tumor necrosis factor GO:0034612 6 5 0,000 4,743E-03 0,07395461 ! mRNA transcription GO:0009299 6 5 0,000 4,743E-03 0,07363307 ! response to ATP GO:0033198 5 5 0,000 4,743E-03 0,07331431 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 4,743E-03 0,0729983 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 4,743E-03 0,07268501 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4,743E-03 0,07237439 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 4,743E-03 0,07206641 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4,743E-03 0,07176104 ! multivesicular body GO:0005771 5 5 0,000 4,743E-03 0,07145826 ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,743E-03 0,07115801 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 4,743E-03 0,07086028 ! forebrain neuron development GO:0021884 6 5 0,000 4,743E-03 0,07056503 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 4,743E-03 0,07027223 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 4,743E-03 0,06998184 ! demethylase activity GO:0032451 5 5 0,000 4,743E-03 0,06969385 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 4,743E-03 0,06940822 ! epithelial cell maturation GO:0002070 5 5 0,000 4,743E-03 0,06912492 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 4,743E-03 0,06884393 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 4,743E-03 0,06856521 ! zymogen granule GO:0042588 5 5 0,000 4,743E-03 0,06828874 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 4,743E-03 0,06801448 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,743E-03 0,06774243 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,743E-03 0,06747254 ! early endosome to late endosome transport GO:0045022 5 5 0,000 4,743E-03 0,06720479 ! positive regulation of translational initiation GO:0045948 5 5 0,000 4,743E-03 0,06693916 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 4,743E-03 0,06667562 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4,743E-03 0,06641414 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 4,743E-03 0,06615471 ! proteoglycan binding GO:0043394 9 5 0,000 4,743E-03 0,0658973 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 4,743E-03 0,06564189 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 4,743E-03 0,06538844 ! zinc ion homeostasis GO:0055069 5 5 0,000 4,743E-03 0,06513695 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 4,743E-03 0,06488738 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 4,743E-03 0,06463972 ! activated T cell proliferation GO:0050798 6 5 0,000 4,743E-03 0,06439394 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 4,743E-03 0,06415002 ! dynein binding GO:0045502 5 5 0,000 4,743E-03 0,06390795 ! regulation of dendrite development GO:0050773 5 5 0,000 4,743E-03 0,06366769 ! cardiac muscle cell development GO:0055013 5 5 0,000 4,743E-03 0,06342924 ! anterograde axon cargo transport GO:0008089 5 5 0,000 4,743E-03 0,06319256 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,743E-03 0,06295764 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4,743E-03 0,06272447 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 4,743E-03 0,06249301 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4,743E-03 0,06226326 ! MutLalpha complex binding GO:0032405 6 5 0,000 4,743E-03 0,06203519 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 4,743E-03 0,06180878 ! high-density lipoprotein binding GO:0008035 5 5 0,000 4,743E-03 0,06158402 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 4,743E-03 0,06136089 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 4,743E-03 0,06113937 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 4,743E-03 0,06091945 ! centromeric DNA binding GO:0019237 5 5 0,000 4,743E-03 0,0607011 ! cyclohydrolase activity GO:0019238 5 5 0,000 4,743E-03 0,06048431 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,743E-03 0,06026906 ! positive T cell selection GO:0043368 9 5 0,000 4,743E-03 0,06005534 ! neural tube patterning GO:0021532 5 5 0,000 4,743E-03 0,05984313 ! amylase activity GO:0016160 5 5 0,000 4,743E-03 0,05963242 ! metaphase plate congression GO:0051310 5 5 0,000 4,743E-03 0,05942318 ! regulation of sterol transport GO:0032371 5 5 0,000 4,743E-03 0,05921541 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 4,743E-03 0,05900908 ! oxygen homeostasis GO:0032364 5 5 0,000 4,743E-03 0,05880419 ! skeletal muscle regeneration GO:0043403 5 5 0,000 4,743E-03 0,05860071 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 4,743E-03 0,05839864 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 4,743E-03 0,05819796 ! SAP kinase activity GO:0016909 5 5 0,000 4,743E-03 0,05799865 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 4,743E-03 0,0578007 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 4,743E-03 0,0576041 ! alpha-mannosidase activity GO:0004559 6 5 0,000 4,743E-03 0,05740884 ! alpha-glucosidase activity GO:0004558 6 5 0,000 4,743E-03 0,05721489 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4,743E-03 0,05702224 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 4,743E-03 0,05683089 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 4,743E-03 0,05664082 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4,743E-03 0,05645202 ! ribonuclease H activity GO:0004523 5 5 0,000 4,743E-03 0,05626447 ! CARD domain binding GO:0050700 5 5 0,000 4,743E-03 0,05607817 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 4,743E-03 0,05589309 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4,743E-03 0,05570923 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 4,743E-03 0,05552658 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,743E-03 0,05534512 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4,743E-03 0,05516484 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4,743E-03 0,05498574 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 4,743E-03 0,05480779 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 4,743E-03 0,05463099 ! ceramidase activity GO:0017040 5 5 0,000 4,743E-03 0,05445533 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 4,743E-03 0,05428079 ! GTP-Rho binding GO:0017049 5 5 0,000 4,743E-03 0,05410737 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4,743E-03 0,05393505 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 4,743E-03 0,05376383 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 4,743E-03 0,05359369 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 4,743E-03 0,05342463 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4,743E-03 0,05325662 ! TAP complex GO:0042825 5 5 0,000 4,743E-03 0,05308968 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4,743E-03 0,05292377 ! actinin binding GO:0042805 6 5 0,000 4,743E-03 0,0527589 ! secretory granule organization GO:0033363 5 5 0,000 4,743E-03 0,05259505 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 4,743E-03 0,05243222 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4,743E-03 0,05227039 ! striatum development GO:0021756 5 5 0,000 4,743E-03 0,05210956 ! photoreceptor inner segment GO:0001917 5 5 0,000 4,743E-03 0,05194971 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 4,743E-03 0,05179085 ! aldehyde-lyase activity GO:0016832 5 5 0,000 4,743E-03 0,05163295 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 4,743E-03 0,05147601 ! T cell activation during immune response GO:0002286 5 5 0,000 4,743E-03 0,05132002 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4,743E-03 0,05116497 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 4,743E-03 0,05101086 ! dystroglycan complex GO:0016011 6 5 0,000 4,743E-03 0,05085768 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 4,743E-03 0,05070541 ! neural plate development GO:0001840 5 5 0,000 4,743E-03 0,05055405 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 4,743E-03 0,05040359 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 4,743E-03 0,05025403 ! phosphopantetheine binding GO:0031177 5 5 0,000 4,743E-03 0,05010534 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 4,743E-03 0,04995754 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 4,743E-03 0,04981061 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 4,743E-03 0,04966454 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4,743E-03 0,04951932 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 4,743E-03 0,04937495 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 4,743E-03 0,04923141 ! retina homeostasis GO:0001895 5 5 0,000 4,743E-03 0,04908871 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 4,743E-03 0,04894684 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 4,743E-03 0,04880578 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 4,743E-03 0,04866554 ! collagen type IV GO:0005587 5 5 0,000 4,743E-03 0,04852609 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4,743E-03 0,04838745 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 4,743E-03 0,04824959 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 4,743E-03 0,04811252 ! spindle assembly GO:0051225 5 5 0,000 4,743E-03 0,04797622 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,743E-03 0,0478407 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 4,743E-03 0,04770593 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 4,743E-03 0,04757193 ! protein amino acid prenylation GO:0018346 5 5 0,000 4,743E-03 0,04743867 ! stem cell division GO:0017145 5 5 0,000 4,743E-03 0,04730616 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4,743E-03 0,04717439 ! phospholipid scrambling GO:0017121 5 5 0,000 4,743E-03 0,04704335 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 4,743E-03 0,04691304 ! regulation of humoral immune response GO:0002920 9 5 0,000 4,743E-03 0,04678344 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 4,743E-03 0,04665456 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 4,743E-03 0,04652639 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4,743E-03 0,04639892 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 4,743E-03 0,04627215 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 4,743E-03 0,04614607 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4,743E-03 0,04602067 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4,743E-03 0,04589595 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4,743E-03 0,04577191 ! polyol transport GO:0015791 6 5 0,000 4,743E-03 0,04564853 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 4,743E-03 0,04552582 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4,743E-03 0,04540377 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 4,743E-03 0,04528237 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 4,743E-03 0,04516162 ! cobalt ion transport GO:0006824 5 5 0,000 4,743E-03 0,04504151 ! response to zinc ion GO:0010043 5 5 0,000 4,743E-03 0,04492203 ! poly(U) RNA binding GO:0008266 5 5 0,000 4,743E-03 0,04480319 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 4,743E-03 0,04468498 ! adaptation of signaling pathway GO:0022401 5 5 0,000 4,743E-03 0,04456739 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 4,743E-03 0,04445041 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 4,743E-03 0,04433405 ! sensory perception of bitter taste GO:0050913 5 5 0,000 4,743E-03 0,04421829 ! regulation of dopamine uptake GO:0051584 5 5 0,000 4,743E-03 0,04410314 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 4,743E-03 0,04398859 ! protein maturation by protein folding GO:0022417 5 5 0,000 4,743E-03 0,04387463 ! neuron remodeling GO:0016322 6 5 0,000 4,743E-03 0,04376126 ! neurexin binding GO:0042043 5 5 0,000 4,743E-03 0,04364847 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 4,743E-03 0,04353626 ! regulation of potassium ion transport GO:0043266 5 5 0,000 4,743E-03 0,04342463 ! low-density lipoprotein particle GO:0034362 5 5 0,000 4,743E-03 0,04331357 ! chemoattractant activity GO:0042056 5 5 0,000 4,743E-03 0,04320308 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 4,743E-03 0,04309315 ! lipoic acid binding GO:0031405 5 5 0,000 4,743E-03 0,04298377 ! lithium ion binding GO:0031403 6 5 0,000 4,743E-03 0,04287495 ! lipoprotein particle clearance GO:0034381 5 5 0,000 4,743E-03 0,04276668 ! grooming behavior GO:0007625 5 5 0,000 4,743E-03 0,04265896 ! sequestering of actin monomers GO:0042989 5 5 0,000 4,743E-03 0,04255178 ! cobalamin binding GO:0031419 5 5 0,000 4,743E-03 0,04244513 ! retinoic acid binding GO:0001972 5 5 0,000 4,743E-03 0,04233902 ! response to axon injury GO:0048678 5 5 0,000 4,743E-03 0,04223343 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4,743E-03 0,04212837 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 4,743E-03 0,04202384 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 4,743E-03 0,04191982 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 4,743E-03 0,04181631 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 4,743E-03 0,04171332 ! female pronucleus GO:0001939 5 5 0,000 4,743E-03 0,04161083 ! F-actin capping protein complex GO:0008290 5 5 0,000 4,743E-03 0,04150884 ! DNA topoisomerase activity GO:0003916 5 5 0,000 4,743E-03 0,04140735 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 4,743E-03 0,04130636 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 4,743E-03 0,04120586 ! dorsal spinal cord development GO:0021516 5 5 0,000 4,743E-03 0,04110584 ! ceramide catabolic process GO:0046514 5 5 0,000 4,743E-03 0,04100631 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4,743E-03 0,04090726 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4,743E-03 0,04080869 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 4,743E-03 0,04071059 ! Rap GTPase activator activity GO:0046582 5 5 0,000 4,743E-03 0,04061297 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 4,743E-03 0,0405158 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 4,743E-03 0,04041911 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 4,743E-03 0,04032287 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 4,743E-03 0,04022709 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 4,743E-03 0,04013177 ! neutrophil activation GO:0042119 5 5 0,000 4,743E-03 0,04003689 ! regulation of response to food GO:0032095 5 5 0,000 4,743E-03 0,03994247 ! response to food GO:0032094 5 5 0,000 4,743E-03 0,03984849 ! hedgehog receptor activity GO:0008158 5 5 0,000 4,743E-03 0,03975494 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 4,743E-03 0,03966184 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4,743E-03 0,03956917 ! organ growth GO:0035265 7 5 0,000 4,743E-03 0,03947694 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 4,743E-03 0,03938513 ! small-subunit processome GO:0032040 5 5 0,000 4,743E-03 0,03929375 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 4,743E-03 0,03920279 ! myosin heavy chain binding GO:0032036 5 5 0,000 4,743E-03 0,03911226 ! nucleoside salvage GO:0043174 7 5 0,000 4,743E-03 0,03902213 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 4,743E-03 0,03893243 ! GPI anchor binding GO:0034235 6 5 0,000 4,743E-03 0,03884313 ! thrombin receptor activity GO:0015057 5 5 0,000 4,743E-03 0,03875425 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 4,743E-03 0,03866577 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 4,743E-03 0,03857769 ! dendritic shaft GO:0043198 5 5 0,000 4,743E-03 0,03849001 ! terminal button GO:0043195 8 5 0,000 4,743E-03 0,03840274 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4,743E-03 0,03831585 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 4,743E-03 0,03822936 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 4,743E-03 0,03814326 ! G2/M transition checkpoint GO:0031576 5 5 0,000 4,743E-03 0,03805754 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 4,743E-03 0,03797221 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 4,743E-03 0,03788726 ! response to UV-C GO:0010225 5 5 0,000 4,743E-03 0,03780269 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 4,743E-03 0,0377185 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 4,743E-03 0,03763468 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 4,743E-03 0,03755123 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 4,743E-03 0,03746816 ! IgE binding GO:0019863 5 5 0,000 4,743E-03 0,03738544 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 4,743E-03 0,0373031 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 4,743E-03 0,03722111 ! response to cadmium ion GO:0046686 5 5 0,000 4,743E-03 0,03713949 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 4,743E-03 0,03705822 ! hair follicle maturation GO:0048820 5 5 0,000 4,743E-03 0,03697731 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 4,743E-03 0,03689675 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 4,743E-03 0,03681654 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,743E-03 0,03673667 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4,743E-03 0,03665716 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4,743E-03 0,03657798 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4,743E-03 0,03649915 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 4,743E-03 0,03642066 ! peroxisome fission GO:0016559 5 5 0,000 4,743E-03 0,0363425 ! alpha-tubulin binding GO:0043014 5 5 0,000 4,743E-03 0,03626468 ! mitotic recombination GO:0006312 5 5 0,000 4,743E-03 0,03618719 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,743E-03 0,03611004 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 4,743E-03 0,03603321 ! positive regulation of chemokine production GO:0032722 5 5 0,000 4,743E-03 0,0359567 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,743E-03 0,03588052 ! muscle cell proliferation GO:0033002 5 5 0,000 4,743E-03 0,03580466 ! membrane to membrane docking GO:0022614 5 5 0,000 4,743E-03 0,03572913 ! translation activator activity GO:0008494 5 5 0,000 4,743E-03 0,03565391 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 4,743E-03 0,03557901 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 4,743E-03 0,03550442 ! histamine receptor activity GO:0004969 5 5 0,000 4,743E-03 0,03543014 ! dopamine receptor activity GO:0004952 5 5 0,000 4,743E-03 0,03535617 ! galactosidase activity GO:0015925 5 5 0,000 4,743E-03 0,03528251 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 4,743E-03 0,03520916 ! cellular response to nutrient GO:0031670 5 5 0,000 4,743E-03 0,03513611 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 4,743E-03 0,03506337 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 4,743E-03 0,03499092 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 4,743E-03 0,03491878 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4,743E-03 0,03484693 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 4,743E-03 0,03477537 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 4,743E-03 0,03470411 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 4,743E-03 0,03463314 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 4,743E-03 0,03456246 ! progesterone metabolic process GO:0042448 5 5 0,000 4,743E-03 0,03449207 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 4,743E-03 0,03442196 ! disaccharide metabolic process GO:0005984 5 5 0,000 4,743E-03 0,03435214 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 4,743E-03 0,0342826 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 4,743E-03 0,03421335 ! histone acetyltransferase binding GO:0035035 5 5 0,000 4,743E-03 0,03414437 ! endosome to lysosome transport GO:0008333 5 5 0,000 4,743E-03 0,03407567 ! glial cell migration GO:0008347 5 5 0,000 4,743E-03 0,03400724 ! S-acyltransferase activity GO:0016417 5 5 0,000 4,743E-03 0,03393909 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 4,743E-03 0,03387121 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 4,743E-03 0,03380361 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4,743E-03 0,03373627 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 4,743E-03 0,0336692 ! asparaginase activity GO:0004067 5 5 0,000 4,743E-03 0,03360239 ! insemination GO:0007320 5 5 0,000 4,743E-03 0,03353585 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4,743E-03 0,03346958 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 4,743E-03 0,03340356 ! aminoacylase activity GO:0004046 5 5 0,000 4,743E-03 0,03333781 ! receptor biosynthetic process GO:0032800 5 5 0,000 4,743E-03 0,03327231 ! penetration of zona pellucida GO:0007341 5 5 0,000 4,743E-03 0,03320707 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 4,743E-03 0,03314209 ! aldehyde reductase activity GO:0004032 5 5 0,000 4,743E-03 0,03307736 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 4,743E-03 0,03301288 ! unconventional myosin complex GO:0016461 5 5 0,000 4,743E-03 0,03294865 ! carnitine metabolic process GO:0009437 5 5 0,000 4,743E-03 0,03288467 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 5,689E-03 0,03936776 ! regulation of helicase activity GO:0051095 6 6 0,000 5,689E-03 0,03929162 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 5,689E-03 0,03921576 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 5,689E-03 0,0391402 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 5,689E-03 0,03906493 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 5,689E-03 0,03898995 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 5,689E-03 0,03891526 ! ephrin receptor binding GO:0046875 7 6 0,000 5,689E-03 0,03884085 ! biotin binding GO:0009374 7 6 0,000 5,689E-03 0,03876673 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 5,689E-03 0,03869289 ! insulin receptor substrate binding GO:0043560 7 6 0,000 5,689E-03 0,03861933 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 5,689E-03 0,03854604 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 5,689E-03 0,03847304 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 5,689E-03 0,03840031 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 5,689E-03 0,03832786 ! neuron adhesion GO:0007158 6 6 0,000 5,689E-03 0,03825568 ! establishment of tissue polarity GO:0007164 7 6 0,000 5,689E-03 0,03818377 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 5,689E-03 0,03811213 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 5,689E-03 0,03804076 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 5,689E-03 0,03796965 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 5,689E-03 0,03789882 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 5,689E-03 0,03782824 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 5,689E-03 0,03775793 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 5,689E-03 0,03768788 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 5,689E-03 0,03761808 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 5,689E-03 0,03754855 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 5,689E-03 0,03747927 ! cytoplasmic microtubule GO:0005881 7 6 0,000 5,689E-03 0,03741025 ! Arp2/3 protein complex GO:0005885 7 6 0,000 5,689E-03 0,03734148 ! neurofilament GO:0005883 6 6 0,000 5,689E-03 0,03727296 ! glial cell fate commitment GO:0021781 6 6 0,000 5,689E-03 0,0372047 ! dynactin complex GO:0005869 6 6 0,000 5,689E-03 0,03713668 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 5,689E-03 0,03706891 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 5,689E-03 0,03700139 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 5,689E-03 0,03693412 ! lipopolysaccharide binding GO:0001530 6 6 0,000 5,689E-03 0,03686709 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 5,689E-03 0,0368003 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 5,689E-03 0,03673375 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 5,689E-03 0,03666745 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 5,689E-03 0,03660138 ! protein lipoylation GO:0009249 6 6 0,000 5,689E-03 0,03653555 ! cysteine metabolic process GO:0006534 6 6 0,000 5,689E-03 0,03646996 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 5,689E-03 0,0364046 ! histidine catabolic process GO:0006548 6 6 0,000 5,689E-03 0,03633947 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 5,689E-03 0,03627458 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 5,689E-03 0,03620992 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 5,689E-03 0,03614549 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 5,689E-03 0,03608129 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 5,689E-03 0,03601731 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 5,689E-03 0,03595357 ! microtubule nucleation GO:0007020 6 6 0,000 5,689E-03 0,03589004 ! proline biosynthetic process GO:0006561 7 6 0,000 5,689E-03 0,03582675 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 5,689E-03 0,03576367 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 5,689E-03 0,03570082 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 5,689E-03 0,03563818 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 5,689E-03 0,03557577 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 5,689E-03 0,03551358 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 5,689E-03 0,0354516 ! paraxial mesoderm development GO:0048339 6 6 0,000 5,689E-03 0,03538984 ! melanosome organization GO:0032438 6 6 0,000 5,689E-03 0,03532829 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 5,689E-03 0,03526695 ! flotillin complex GO:0016600 6 6 0,000 5,689E-03 0,03520583 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 5,689E-03 0,03514492 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 5,689E-03 0,03508422 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 5,689E-03 0,03502373 ! positive regulation of exocytosis GO:0045921 7 6 0,000 5,689E-03 0,03496345 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 5,689E-03 0,03490338 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 5,689E-03 0,03484351 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 5,689E-03 0,03478384 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 5,689E-03 0,03472439 ! nonhomologous end joining complex GO:0070419 6 6 0,000 5,689E-03 0,03466513 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 5,689E-03 0,03460607 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 5,689E-03 0,03454722 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 5,689E-03 0,03448857 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 5,689E-03 0,03443011 ! sodium ion homeostasis GO:0055078 6 6 0,000 5,689E-03 0,03437185 ! protein heterooligomerization GO:0051291 6 6 0,000 5,689E-03 0,03431379 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 5,689E-03 0,03425593 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 5,689E-03 0,03419826 ! translation termination factor activity GO:0008079 6 6 0,000 5,689E-03 0,03414078 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 5,689E-03 0,0340835 ! astrocyte development GO:0014002 6 6 0,000 5,689E-03 0,03402641 ! protein targeting to lysosome GO:0006622 6 6 0,000 5,689E-03 0,03396951 ! purine base biosynthetic process GO:0009113 7 6 0,000 5,689E-03 0,0339128 ! fibrinolysis GO:0042730 7 6 0,000 5,689E-03 0,03385628 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 5,689E-03 0,03379994 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 5,689E-03 0,0337438 ! B cell lineage commitment GO:0002326 6 6 0,000 5,689E-03 0,03368784 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 5,689E-03 0,03363206 ! response to exogenous dsRNA GO:0043330 6 6 0,000 5,689E-03 0,03357647 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 5,689E-03 0,03352106 ! melanosome transport GO:0032402 6 6 0,000 5,689E-03 0,03346584 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 5,689E-03 0,0334108 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 5,689E-03 0,03335594 ! regulation of dopamine secretion GO:0014059 6 6 0,000 5,689E-03 0,03330125 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 5,689E-03 0,03324675 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 5,689E-03 0,03319243 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,689E-03 0,03313828 ! transcription initiation factor activity GO:0016986 6 6 0,000 5,689E-03 0,03308431 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 5,689E-03 0,03303051 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 5,689E-03 0,03297689 ! Schwann cell development GO:0014044 6 6 0,000 5,689E-03 0,03292344 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 5,689E-03 0,03287017 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 5,689E-03 0,03281707 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 5,689E-03 0,03276414 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 5,689E-03 0,03271138 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 5,689E-03 0,03265879 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 5,689E-03 0,03260636 ! nuclear envelope lumen GO:0005641 6 6 0,000 5,689E-03 0,03255411 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 5,689E-03 0,03250202 ! regulation of meiosis GO:0040020 6 6 0,000 5,689E-03 0,0324501 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 5,689E-03 0,03239835 ! lipoxygenase activity GO:0016165 6 6 0,000 5,689E-03 0,03234676 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 5,689E-03 0,03229533 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 5,689E-03 0,03224407 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 5,689E-03 0,03219297 ! DNA replication factor C complex GO:0005663 6 6 0,000 5,689E-03 0,03214203 ! DNA replication factor A complex GO:0005662 6 6 0,000 5,689E-03 0,03209126 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 5,689E-03 0,03204064 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 5,689E-03 0,03199018 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 5,689E-03 0,03193988 ! chromatin silencing complex GO:0005677 6 6 0,000 5,689E-03 0,03188974 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 5,689E-03 0,03183976 ! B cell homeostasis GO:0001782 7 6 0,000 5,689E-03 0,03178993 ! regulation of respiratory burst GO:0060263 6 6 0,000 5,689E-03 0,03174026 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 5,689E-03 0,03169074 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 5,689E-03 0,03164138 ! MutLalpha complex GO:0032389 6 6 0,000 5,689E-03 0,03159217 ! leading edge membrane GO:0031256 6 6 0,000 5,689E-03 0,03154311 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 5,689E-03 0,03149421 ! peptidyl-histidine modification GO:0018202 6 6 0,000 5,689E-03 0,03144546 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 5,689E-03 0,03139686 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 5,689E-03 0,0313484 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 5,689E-03 0,0313001 ! diuresis GO:0030146 6 6 0,000 5,689E-03 0,03125195 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 5,689E-03 0,03120394 ! glutathione biosynthetic process GO:0006750 6 6 0,000 5,689E-03 0,03115608 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 5,689E-03 0,03110837 ! BBSome GO:0034464 6 6 0,000 5,689E-03 0,0310608 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 5,689E-03 0,03101338 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 5,689E-03 0,03096611 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 5,689E-03 0,03091897 ! sodium channel regulator activity GO:0017080 6 6 0,000 5,689E-03 0,03087198 ! glycolipid catabolic process GO:0019377 6 6 0,000 5,689E-03 0,03082514 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 5,689E-03 0,03077843 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 5,689E-03 0,03073187 ! porphyrin catabolic process GO:0006787 8 6 0,000 5,689E-03 0,03068545 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 5,689E-03 0,03063916 ! positive regulation of glucose import GO:0046326 7 6 0,000 5,689E-03 0,03059302 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 5,689E-03 0,03054702 ! myeloid cell homeostasis GO:0002262 6 6 0,000 5,689E-03 0,03050115 ! lamin binding GO:0005521 6 6 0,000 5,689E-03 0,03045542 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 5,689E-03 0,03040983 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 5,689E-03 0,03036437 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 5,689E-03 0,03031905 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 5,689E-03 0,03027387 ! peroxiredoxin activity GO:0051920 6 6 0,000 5,689E-03 0,03022882 ! complement binding GO:0001848 8 6 0,000 5,689E-03 0,0301839 ! catecholamine transport GO:0051937 6 6 0,000 5,689E-03 0,03013912 ! regulation of sensory perception GO:0051931 6 6 0,000 5,689E-03 0,03009447 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 5,689E-03 0,03004995 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 5,689E-03 0,03000556 ! dipeptidase activity GO:0016805 6 6 0,000 5,689E-03 0,02996131 ! ether hydrolase activity GO:0016803 6 6 0,000 5,689E-03 0,02991718 ! FACIT collagen GO:0005593 6 6 0,000 5,689E-03 0,02987318 ! actin filament polymerization GO:0030041 8 6 0,000 5,689E-03 0,02982932 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 5,689E-03 0,02978558 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 5,689E-03 0,02974197 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 5,689E-03 0,02969849 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 5,689E-03 0,02965513 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 5,689E-03 0,0296119 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 5,689E-03 0,0295688 ! organ regeneration GO:0031100 6 6 0,000 5,689E-03 0,02952582 ! Golgi transport complex GO:0017119 6 6 0,000 5,689E-03 0,02948297 ! sheet-forming collagen GO:0030935 6 6 0,000 5,689E-03 0,02944024 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 5,689E-03 0,02939763 ! positive regulation of coagulation GO:0050820 7 6 0,000 5,689E-03 0,02935515 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 5,689E-03 0,02931279 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 5,689E-03 0,02927056 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 5,689E-03 0,02922844 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 5,689E-03 0,02918644 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 5,689E-03 0,02914457 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 5,689E-03 0,02910282 ! myoblast cell fate commitment GO:0048625 6 6 0,000 5,689E-03 0,02906118 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 5,689E-03 0,02901966 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 5,689E-03 0,02897827 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 5,689E-03 0,02893699 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 5,689E-03 0,02889583 ! nuclear telomere cap complex GO:0000783 6 6 0,000 5,689E-03 0,02885478 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 5,689E-03 0,02881385 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 5,689E-03 0,02877304 ! sterol carrier activity GO:0005498 6 6 0,000 5,689E-03 0,02873234 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 5,689E-03 0,02869176 ! succinate metabolic process GO:0006105 6 6 0,000 5,689E-03 0,02865129 ! myelin sheath GO:0043209 6 6 0,000 5,689E-03 0,02861094 ! perikaryon GO:0043204 7 6 0,000 5,689E-03 0,0285707 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 5,689E-03 0,02853057 ! malate metabolic process GO:0006108 6 6 0,000 5,689E-03 0,02849055 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 5,689E-03 0,02845065 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 5,689E-03 0,02841086 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 5,689E-03 0,02837118 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 5,689E-03 0,02833161 ! rhythmic behavior GO:0007622 7 6 0,000 5,689E-03 0,02829215 ! copulation GO:0007620 6 6 0,000 5,689E-03 0,0282528 ! erythrocyte maturation GO:0043249 6 6 0,000 5,689E-03 0,02821356 ! equilibrioception GO:0050957 6 6 0,000 5,689E-03 0,02817443 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 5,689E-03 0,02813541 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 5,689E-03 0,02809649 ! chemosensory behavior GO:0007635 6 6 0,000 5,689E-03 0,02805769 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 5,689E-03 0,02801899 ! mechanosensory behavior GO:0007638 6 6 0,000 5,689E-03 0,02798039 ! response to interferon-gamma GO:0034341 6 6 0,000 5,689E-03 0,02794191 ! spinal cord patterning GO:0021511 6 6 0,000 5,689E-03 0,02790352 ! cGMP-mediated signaling GO:0019934 6 6 0,000 5,689E-03 0,02786525 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 5,689E-03 0,02782708 ! activation of MAPKKK activity GO:0000185 6 6 0,000 5,689E-03 0,02778901 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 5,689E-03 0,02775105 ! glucosyltransferase activity GO:0046527 6 6 0,000 5,689E-03 0,02771319 ! sphingoid catabolic process GO:0046521 6 6 0,000 5,689E-03 0,02767543 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 5,689E-03 0,02763778 ! activin receptor activity GO:0017002 6 6 0,000 5,689E-03 0,02760022 ! ovulation GO:0030728 6 6 0,000 5,689E-03 0,02756278 ! dopamine binding GO:0035240 7 6 0,000 5,689E-03 0,02752543 ! hyperosmotic response GO:0006972 6 6 0,000 5,689E-03 0,02748818 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 5,689E-03 0,02745103 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 5,689E-03 0,02741399 ! nuclear localization sequence binding GO:0008139 6 6 0,000 5,689E-03 0,02737704 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 5,689E-03 0,0273402 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 5,689E-03 0,02730345 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 5,689E-03 0,0272668 ! poly(A) RNA binding GO:0008143 6 6 0,000 5,689E-03 0,02723025 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 5,689E-03 0,0271938 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 5,689E-03 0,02715744 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 5,689E-03 0,02712118 ! intracellular pH reduction GO:0051452 6 6 0,000 5,689E-03 0,02708502 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 5,689E-03 0,02704896 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 5,689E-03 0,02701299 ! neurotrophin binding GO:0043121 6 6 0,000 5,689E-03 0,02697711 ! ciliary rootlet GO:0035253 6 6 0,000 5,689E-03 0,02694133 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 5,689E-03 0,02690565 ! ruffle organization GO:0031529 6 6 0,000 5,689E-03 0,02687006 ! T cell mediated immunity GO:0002456 6 6 0,000 5,689E-03 0,02683456 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 5,689E-03 0,02679916 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 5,689E-03 0,02676385 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 5,689E-03 0,02672864 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 5,689E-03 0,02669352 ! S-methyltransferase activity GO:0008172 6 6 0,000 5,689E-03 0,02665848 ! phospholipase D activity GO:0004630 6 6 0,000 5,689E-03 0,02662355 ! rRNA modification GO:0000154 6 6 0,000 5,689E-03 0,0265887 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 5,689E-03 0,02655394 ! neuronal ion channel clustering GO:0045161 6 6 0,000 5,689E-03 0,02651928 ! response to UV-B GO:0010224 6 6 0,000 5,689E-03 0,0264847 ! interaction with symbiont GO:0051702 6 6 0,000 5,689E-03 0,02645022 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 5,689E-03 0,02641582 ! IgG binding GO:0019864 6 6 0,000 5,689E-03 0,02638151 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 5,689E-03 0,0263473 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 5,689E-03 0,02631317 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 5,689E-03 0,02627913 ! response to copper ion GO:0046688 6 6 0,000 5,689E-03 0,02624517 ! DNA topological change GO:0006265 6 6 0,000 5,689E-03 0,02621131 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 5,689E-03 0,02617753 ! dendrite morphogenesis GO:0048813 6 6 0,000 5,689E-03 0,02614384 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 5,689E-03 0,02611024 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 5,689E-03 0,02607672 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 5,689E-03 0,02604329 ! nucleosome disassembly GO:0006337 6 6 0,000 5,689E-03 0,02600994 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 5,689E-03 0,02597668 ! regulation of mast cell activation GO:0033003 6 6 0,000 5,689E-03 0,02594351 ! guanylyltransferase activity GO:0070568 6 6 0,000 5,689E-03 0,02591041 ! receptor internalization GO:0031623 7 6 0,000 5,689E-03 0,02587741 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 5,689E-03 0,02584449 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 5,689E-03 0,02581165 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 5,689E-03 0,02577889 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 5,689E-03 0,02574622 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 5,689E-03 0,02571363 ! NuRD complex GO:0016581 6 6 0,000 5,689E-03 0,02568112 ! nucleosome positioning GO:0016584 6 6 0,000 5,689E-03 0,02564869 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 5,689E-03 0,02561635 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 5,689E-03 0,02558409 ! glycine binding GO:0016594 8 6 0,000 5,689E-03 0,02555191 ! costamere GO:0043034 7 6 0,000 5,689E-03 0,02551981 ! A band GO:0031672 6 6 0,000 5,689E-03 0,02548779 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 5,689E-03 0,02545585 ! dopamine biosynthetic process GO:0042416 7 6 0,000 5,689E-03 0,02542399 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 5,689E-03 0,02539221 ! negative regulation of axon extension GO:0030517 6 6 0,000 5,689E-03 0,02536051 ! actin monomer binding GO:0003785 6 6 0,000 5,689E-03 0,02532888 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 5,689E-03 0,02529734 ! lysozyme activity GO:0003796 6 6 0,000 5,689E-03 0,02526588 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 5,689E-03 0,02523449 ! ATP catabolic process GO:0006200 6 6 0,000 5,689E-03 0,02520318 ! determination of adult lifespan GO:0008340 6 6 0,000 5,689E-03 0,02517195 ! somatic stem cell maintenance GO:0035019 6 6 0,000 5,689E-03 0,0251408 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 5,689E-03 0,02510972 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 5,689E-03 0,02507872 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 5,689E-03 0,0250478 ! O-acetyltransferase activity GO:0016413 6 6 0,000 5,689E-03 0,02501695 ! CoA-ligase activity GO:0016405 6 6 0,000 5,689E-03 0,02498618 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 5,689E-03 0,02495549 ! IkappaB kinase complex GO:0008385 6 6 0,000 5,689E-03 0,02492487 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 5,689E-03 0,02489432 ! store-operated calcium channel activity GO:0015279 6 6 0,000 5,689E-03 0,02486385 ! aminomethyltransferase activity GO:0004047 6 6 0,000 5,689E-03 0,02483345 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 5,689E-03 0,02480313 ! alkaline phosphatase activity GO:0004035 6 6 0,000 5,689E-03 0,02477288 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 5,689E-03 0,02474271 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 6,634E-03 0,02881866 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 6,634E-03 0,02878365 ! sleep GO:0030431 7 7 0,000 6,634E-03 0,02874872 ! synaptonemal complex assembly GO:0007130 7 7 0,000 6,634E-03 0,02871387 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 6,634E-03 0,02867911 ! cell proliferation in forebrain GO:0021846 7 7 0,000 6,634E-03 0,02864443 ! meiotic prophase I GO:0007128 7 7 0,000 6,634E-03 0,02860983 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 6,634E-03 0,02857532 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 6,634E-03 0,02854089 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 6,634E-03 0,02850655 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 6,634E-03 0,02847229 ! diphosphotransferase activity GO:0016778 8 7 0,000 6,634E-03 0,02843811 ! actin-myosin filament sliding GO:0033275 7 7 0,000 6,634E-03 0,02840401 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 6,634E-03 0,02836999 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 6,634E-03 0,02833606 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 6,634E-03 0,0283022 ! macrophage chemotaxis GO:0048246 7 7 0,000 6,634E-03 0,02826843 ! cerebral cortex cell migration GO:0021795 7 7 0,000 6,634E-03 0,02823473 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 6,634E-03 0,02820112 ! membrane hyperpolarization GO:0060081 7 7 0,000 6,634E-03 0,02816759 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 6,634E-03 0,02813414 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 6,634E-03 0,02810076 ! DNA replication origin binding GO:0003688 7 7 0,000 6,634E-03 0,02806747 ! ATPase binding GO:0051117 7 7 0,000 6,634E-03 0,02803425 ! positive regulation of glycolysis GO:0045821 7 7 0,000 6,634E-03 0,02800111 ! positive regulation of isotype switching GO:0045830 11 7 0,000 6,634E-03 0,02796805 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 6,634E-03 0,02793507 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 6,634E-03 0,02790217 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 6,634E-03 0,02786934 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 6,634E-03 0,02783659 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 6,634E-03 0,02780392 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 6,634E-03 0,02777133 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 6,634E-03 0,02773881 ! transepithelial chloride transport GO:0030321 7 7 0,000 6,634E-03 0,02770637 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 6,634E-03 0,027674 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 6,634E-03 0,02764171 ! glycine catabolic process GO:0006546 7 7 0,000 6,634E-03 0,02760949 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 6,634E-03 0,02757735 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 6,634E-03 0,02754528 ! response to pH GO:0009268 7 7 0,000 6,634E-03 0,02751329 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,634E-03 0,02748137 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 6,634E-03 0,02744953 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 6,634E-03 0,02741776 ! endosome organization GO:0007032 7 7 0,000 6,634E-03 0,02738606 ! thyroid hormone generation GO:0006590 7 7 0,000 6,634E-03 0,02735444 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 6,634E-03 0,02732289 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 6,634E-03 0,02729141 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 6,634E-03 0,02726 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 6,634E-03 0,02722867 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 6,634E-03 0,02719741 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 6,634E-03 0,02716622 ! retinoid X receptor binding GO:0046965 7 7 0,000 6,634E-03 0,0271351 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 6,634E-03 0,02710405 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 6,634E-03 0,02707308 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 6,634E-03 0,02704217 ! urea metabolic process GO:0019627 7 7 0,000 6,634E-03 0,02701134 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 6,634E-03 0,02698057 ! regulation of type I interferon production GO:0032479 8 7 0,000 6,634E-03 0,02694988 ! peroxisomal matrix GO:0005782 7 7 0,000 6,634E-03 0,02691925 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 6,634E-03 0,0268887 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 6,634E-03 0,02685821 ! p53 binding GO:0002039 7 7 0,000 6,634E-03 0,02682779 ! osteoblast development GO:0002076 8 7 0,000 6,634E-03 0,02679745 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 6,634E-03 0,02676717 ! lipid phosphatase activity GO:0042577 7 7 0,000 6,634E-03 0,02673696 ! male sex determination GO:0030238 7 7 0,000 6,634E-03 0,02670681 ! clathrin binding GO:0030276 8 7 0,000 6,634E-03 0,02667674 ! negative regulation of translational initiation GO:0045947 7 7 0,000 6,634E-03 0,02664673 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 6,634E-03 0,02661679 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 6,634E-03 0,02658692 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 6,634E-03 0,02655711 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 6,634E-03 0,02652737 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 6,634E-03 0,0264977 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 6,634E-03 0,02646809 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 6,634E-03 0,02643855 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 6,634E-03 0,02640908 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,634E-03 0,02637967 ! protein retention in ER lumen GO:0006621 7 7 0,000 6,634E-03 0,02635033 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 6,634E-03 0,02632105 ! peptidyl-arginine modification GO:0018195 7 7 0,000 6,634E-03 0,02629183 ! regulation of circadian rhythm GO:0042752 7 7 0,000 6,634E-03 0,02626269 ! Hsp90 protein binding GO:0051879 7 7 0,000 6,634E-03 0,0262336 ! MutSalpha complex binding GO:0032407 8 7 0,000 6,634E-03 0,02620458 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 6,634E-03 0,02617563 ! establishment of melanosome localization GO:0032401 7 7 0,000 6,634E-03 0,02614674 ! gas homeostasis GO:0033483 7 7 0,000 6,634E-03 0,02611791 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 6,634E-03 0,02608914 ! subpallium development GO:0021544 7 7 0,000 6,634E-03 0,02606044 ! laminin-1 complex GO:0005606 7 7 0,000 6,634E-03 0,0260318 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 6,634E-03 0,02600323 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 6,634E-03 0,02597472 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 6,634E-03 0,02594627 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 6,634E-03 0,02591788 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 6,634E-03 0,02588955 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 6,634E-03 0,02586129 ! establishment of chromosome localization GO:0051303 7 7 0,000 6,634E-03 0,02583309 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 6,634E-03 0,02580495 ! regulation of cell division GO:0051302 7 7 0,000 6,634E-03 0,02577687 ! chromatin assembly complex GO:0005678 7 7 0,000 6,634E-03 0,02574885 ! sex chromatin GO:0001739 7 7 0,000 6,634E-03 0,02572089 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 6,634E-03 0,025693 ! chitinase activity GO:0004568 7 7 0,000 6,634E-03 0,02566516 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 6,634E-03 0,02563738 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 6,634E-03 0,02560967 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 6,634E-03 0,02558201 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 6,634E-03 0,02555441 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 6,634E-03 0,02552688 ! molybdenum ion binding GO:0030151 7 7 0,000 6,634E-03 0,0254994 ! positive regulation of epidermis development GO:0045684 7 7 0,000 6,634E-03 0,02547198 ! proteasome regulator activity GO:0010860 7 7 0,000 6,634E-03 0,02544462 ! antibiotic transport GO:0042891 7 7 0,000 6,634E-03 0,02541732 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 6,634E-03 0,02539008 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 6,634E-03 0,02536289 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 6,634E-03 0,02533577 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 6,634E-03 0,0253087 ! Wnt receptor activity GO:0042813 7 7 0,000 6,634E-03 0,02528169 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 6,634E-03 0,02525474 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 6,634E-03 0,02522784 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 6,634E-03 0,025201 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 6,634E-03 0,02517422 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 6,634E-03 0,0251475 ! blastocyst growth GO:0001832 7 7 0,000 6,634E-03 0,02512083 ! pigment granule transport GO:0051904 7 7 0,000 6,634E-03 0,02509422 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 6,634E-03 0,02506766 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 6,634E-03 0,02504117 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 6,634E-03 0,02501472 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 6,634E-03 0,02498834 ! cerebellar cortex formation GO:0021697 8 7 0,000 6,634E-03 0,024962 ! activation of innate immune response GO:0002218 7 7 0,000 6,634E-03 0,02493573 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 6,634E-03 0,02490951 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 6,634E-03 0,02488334 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 6,634E-03 0,02485723 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 6,634E-03 0,02483118 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 6,634E-03 0,02480518 ! regulation of muscle adaptation GO:0043502 7 7 0,000 6,634E-03 0,02477923 ! sequestering of metal ion GO:0051238 7 7 0,000 6,634E-03 0,02475334 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 6,634E-03 0,0247275 ! membrane attack complex GO:0005579 7 7 0,000 6,634E-03 0,02470171 ! fibrinogen complex GO:0005577 7 7 0,000 6,634E-03 0,02467598 ! septin complex GO:0031105 9 7 0,000 6,634E-03 0,0246503 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 6,634E-03 0,02462468 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 6,634E-03 0,02459911 ! cellular anion homeostasis GO:0030002 7 7 0,000 6,634E-03 0,02457359 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 6,634E-03 0,02454813 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 6,634E-03 0,02452271 ! autophagic vacuole formation GO:0000045 8 7 0,000 6,634E-03 0,02449736 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 6,634E-03 0,02447205 ! translation initiation factor binding GO:0031369 7 7 0,000 6,634E-03 0,02444679 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 6,634E-03 0,02442159 ! activin binding GO:0048185 7 7 0,000 6,634E-03 0,02439644 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 6,634E-03 0,02437134 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 6,634E-03 0,02434629 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 6,634E-03 0,0243213 ! phototransduction, visible light GO:0007603 7 7 0,000 6,634E-03 0,02429635 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 6,634E-03 0,02427146 ! lipoprotein transport GO:0042953 7 7 0,000 6,634E-03 0,02424661 ! cell division site part GO:0032155 7 7 0,000 6,634E-03 0,02422182 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 6,634E-03 0,02419708 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 6,634E-03 0,02417239 ! phospholipid efflux GO:0033700 7 7 0,000 6,634E-03 0,02414775 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 6,634E-03 0,02412316 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 6,634E-03 0,02409862 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 6,634E-03 0,02407413 ! poly-purine tract binding GO:0070717 7 7 0,000 6,634E-03 0,02404969 ! T-helper 1 type immune response GO:0042088 7 7 0,000 6,634E-03 0,0240253 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 6,634E-03 0,02400095 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 6,634E-03 0,02397666 ! leukocyte degranulation GO:0043299 7 7 0,000 6,634E-03 0,02395242 ! bile acid and bile salt transport GO:0015721 7 7 0,000 6,634E-03 0,02392822 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 6,634E-03 0,02390408 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 6,634E-03 0,02387998 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 6,634E-03 0,02385593 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 6,634E-03 0,02383193 ! pigment granule organization GO:0048753 7 7 0,000 6,634E-03 0,02380798 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 6,634E-03 0,02378408 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 6,634E-03 0,02376022 ! regulation of pigmentation during development GO:0048070 10 7 0,000 6,634E-03 0,02373642 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 6,634E-03 0,02371265 ! macrophage activation GO:0042116 7 7 0,000 6,634E-03 0,02368894 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 6,634E-03 0,02366528 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 6,634E-03 0,02364166 ! galactose metabolic process GO:0006012 7 7 0,000 6,634E-03 0,02361809 ! vesicle fusion GO:0006906 7 7 0,000 6,634E-03 0,02359456 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 6,634E-03 0,02357109 ! glycerol ether catabolic process GO:0044269 7 7 0,000 6,634E-03 0,02354766 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 6,634E-03 0,02352427 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 6,634E-03 0,02350093 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 6,634E-03 0,02347764 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 6,634E-03 0,0234544 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 6,634E-03 0,0234312 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 6,634E-03 0,02340805 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 6,634E-03 0,02338494 ! inclusion body GO:0016234 7 7 0,000 6,634E-03 0,02336188 ! parturition GO:0007567 7 7 0,000 6,634E-03 0,02333886 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 6,634E-03 0,02331589 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 6,634E-03 0,02329296 ! intercalated disc GO:0014704 8 7 0,000 6,634E-03 0,02327008 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 6,634E-03 0,02324724 ! neural nucleus development GO:0048857 7 7 0,000 6,634E-03 0,02322445 ! intermediate filament organization GO:0045109 8 7 0,000 6,634E-03 0,02320171 ! skeletal muscle contraction GO:0003009 7 7 0,000 6,634E-03 0,023179 ! response to antibiotic GO:0046677 7 7 0,000 6,634E-03 0,02315635 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 6,634E-03 0,02313373 ! preribosome GO:0030684 7 7 0,000 6,634E-03 0,02311116 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 6,634E-03 0,02308864 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 6,634E-03 0,02306616 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 6,634E-03 0,02304372 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 6,634E-03 0,02302132 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 6,634E-03 0,02299897 ! phosphofructokinase activity GO:0008443 7 7 0,000 6,634E-03 0,02297667 ! postreplication repair GO:0006301 7 7 0,000 6,634E-03 0,0229544 ! gap junction channel activity GO:0005243 7 7 0,000 6,634E-03 0,02293218 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 6,634E-03 0,02291 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 6,634E-03 0,02288787 ! transcription termination GO:0006353 8 7 0,000 6,634E-03 0,02286577 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 6,634E-03 0,02284372 ! tetracycline transporter activity GO:0008493 7 7 0,000 6,634E-03 0,02282172 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 6,634E-03 0,02279975 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 6,634E-03 0,02277783 ! melanocortin receptor activity GO:0004977 7 7 0,000 6,634E-03 0,02275595 ! coenzyme A metabolic process GO:0015936 8 7 0,000 6,634E-03 0,02273411 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 6,634E-03 0,02271231 ! regulation of macrophage activation GO:0043030 7 7 0,000 6,634E-03 0,02269056 ! cytidine deaminase activity GO:0004126 7 7 0,000 6,634E-03 0,02266884 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 6,634E-03 0,02264717 ! apical protein localization GO:0045176 7 7 0,000 6,634E-03 0,02262554 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 6,634E-03 0,02260395 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 6,634E-03 0,0225824 ! virion binding GO:0046790 10 7 0,000 6,634E-03 0,0225609 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 6,634E-03 0,02253943 ! protein prenyltransferase activity GO:0008318 7 7 0,000 6,634E-03 0,02251801 ! protein modification by small protein removal GO:0070646 7 7 0,000 6,634E-03 0,02249662 ! adult feeding behavior GO:0008343 7 7 0,000 6,634E-03 0,02247528 ! CoA carboxylase activity GO:0016421 7 7 0,000 6,634E-03 0,02245397 ! microtubule basal body GO:0005932 7 7 0,000 6,634E-03 0,02243271 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 6,634E-03 0,02241149 ! embryonic heart tube development GO:0035050 7 7 0,000 6,634E-03 0,0223903 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 6,634E-03 0,02236916 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 6,634E-03 0,02234806 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 6,634E-03 0,022327 ! rRNA transcription GO:0009303 8 8 0,000 7,578E-03 0,0254813 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 7,578E-03 0,02545733 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 7,578E-03 0,0254334 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 7,578E-03 0,02540952 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 7,578E-03 0,02538568 ! cation:chloride symporter activity GO:0015377 9 8 0,000 7,578E-03 0,02536189 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 7,578E-03 0,02533815 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 7,578E-03 0,02531444 ! male meiosis GO:0007140 8 8 0,000 7,578E-03 0,02529079 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 7,578E-03 0,02526717 ! N-glycan processing GO:0006491 8 8 0,000 7,578E-03 0,0252436 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 7,578E-03 0,02522007 ! protein self-association GO:0043621 8 8 0,000 7,578E-03 0,02519659 ! RNA methylation GO:0001510 8 8 0,000 7,578E-03 0,02517315 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 7,578E-03 0,02514976 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 7,578E-03 0,02512641 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 7,578E-03 0,0251031 ! hexokinase activity GO:0004396 8 8 0,000 7,578E-03 0,02507983 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 7,578E-03 0,02505661 ! guanylate cyclase activity GO:0004383 8 8 0,000 7,578E-03 0,02503343 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 7,578E-03 0,0250103 ! troponin complex GO:0005861 9 8 0,000 7,578E-03 0,0249872 ! smoothened signaling pathway GO:0007224 8 8 0,000 7,578E-03 0,02496415 ! keratinocyte proliferation GO:0043616 8 8 0,000 7,578E-03 0,02494114 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 7,578E-03 0,02491818 ! ganglioside metabolic process GO:0001573 8 8 0,000 7,578E-03 0,02489525 ! reflex GO:0060004 11 8 0,000 7,578E-03 0,02487237 ! small protein activating enzyme activity GO:0008641 10 8 0,000 7,578E-03 0,02484953 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 7,578E-03 0,02482673 ! hemoglobin metabolic process GO:0020027 8 8 0,000 7,578E-03 0,02480398 ! protein targeting to ER GO:0045047 9 8 0,000 7,578E-03 0,02478126 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 7,578E-03 0,02475859 ! arginine catabolic process GO:0006527 8 8 0,000 7,578E-03 0,02473596 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 7,578E-03 0,02471337 ! malate dehydrogenase activity GO:0016615 8 8 0,000 7,578E-03 0,02469082 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 7,578E-03 0,02466831 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 7,578E-03 0,02464585 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 7,578E-03 0,02462342 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 7,578E-03 0,02460104 ! proline metabolic process GO:0006560 9 8 0,000 7,578E-03 0,02457869 ! melanosome membrane GO:0033162 10 8 0,000 7,578E-03 0,02455639 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 7,578E-03 0,02453413 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 7,578E-03 0,0245119 ! melanin metabolic process GO:0006582 9 8 0,000 7,578E-03 0,02448972 ! death receptor activity GO:0005035 8 8 0,000 7,578E-03 0,02446758 ! Golgi lumen GO:0005796 8 8 0,000 7,578E-03 0,02444547 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 7,578E-03 0,02442341 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 7,578E-03 0,02440139 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 7,578E-03 0,02437941 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 7,578E-03 0,02435746 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 7,578E-03 0,02433556 ! Rac protein signal transduction GO:0016601 8 8 0,000 7,578E-03 0,02431369 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 7,578E-03 0,02429187 ! lens development in camera-type eye GO:0002088 8 8 0,000 7,578E-03 0,02427008 ! positive regulation of vasodilation GO:0045909 8 8 0,000 7,578E-03 0,02424833 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 7,578E-03 0,02422662 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 7,578E-03 0,02420496 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 7,578E-03 0,02418332 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 7,578E-03 0,02416173 ! Schwann cell differentiation GO:0014037 8 8 0,000 7,578E-03 0,02414018 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 7,578E-03 0,02411866 ! axon guidance receptor activity GO:0008046 8 8 0,000 7,578E-03 0,02409719 ! protein targeting to vacuole GO:0006623 8 8 0,000 7,578E-03 0,02407575 ! response to tropane GO:0014073 10 8 0,000 7,578E-03 0,02405435 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 7,578E-03 0,02403298 ! melanosome localization GO:0032400 8 8 0,000 7,578E-03 0,02401166 ! response to amine stimulus GO:0014075 10 8 0,000 7,578E-03 0,02399037 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 7,578E-03 0,02396912 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 7,578E-03 0,02394791 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 7,578E-03 0,02392674 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 7,578E-03 0,0239056 ! holo TFIIH complex GO:0005675 8 8 0,000 7,578E-03 0,0238845 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 7,578E-03 0,02386344 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 7,578E-03 0,02384241 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 7,578E-03 0,02382143 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 7,578E-03 0,02380047 ! vitamin transporter activity GO:0051183 8 8 0,000 7,578E-03 0,02377956 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 7,578E-03 0,02375868 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 7,578E-03 0,02373784 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 7,578E-03 0,02371704 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 7,578E-03 0,02369627 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 7,578E-03 0,02367554 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 7,578E-03 0,02365484 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 7,578E-03 0,02363418 ! regulation of synaptogenesis GO:0051963 8 8 0,000 7,578E-03 0,02361356 ! oocyte differentiation GO:0009994 8 8 0,000 7,578E-03 0,02359297 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 7,578E-03 0,02357242 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 7,578E-03 0,02355191 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 7,578E-03 0,02353143 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 7,578E-03 0,02351098 ! establishment of pigment granule localization GO:0051905 8 8 0,000 7,578E-03 0,02349057 ! regulation of telomere maintenance GO:0032204 8 8 0,000 7,578E-03 0,0234702 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 7,578E-03 0,02344986 ! amino sugar catabolic process GO:0046348 8 8 0,000 7,578E-03 0,02342956 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 7,578E-03 0,02340929 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 7,578E-03 0,02338906 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 7,578E-03 0,02336886 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 7,578E-03 0,0233487 ! cholesterol transporter activity GO:0017127 8 8 0,000 7,578E-03 0,02332857 ! GABA receptor binding GO:0050811 8 8 0,000 7,578E-03 0,02330848 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 7,578E-03 0,02328842 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 7,578E-03 0,02326839 ! regulation of developmental growth GO:0048638 8 8 0,000 7,578E-03 0,0232484 ! GMP binding GO:0019002 10 8 0,000 7,578E-03 0,02322845 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 7,578E-03 0,02320852 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 7,578E-03 0,02318864 ! prostate gland development GO:0030850 8 8 0,000 7,578E-03 0,02316878 ! 7S RNA binding GO:0008312 9 8 0,000 7,578E-03 0,02314896 ! neutral lipid catabolic process GO:0046461 8 8 0,000 7,578E-03 0,02312918 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 7,578E-03 0,02310943 ! reproductive behavior GO:0019098 8 8 0,000 7,578E-03 0,02308971 ! cell volume homeostasis GO:0006884 9 8 0,000 7,578E-03 0,02307003 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 7,578E-03 0,02305037 ! oligopeptide transport GO:0006857 8 8 0,000 7,578E-03 0,02303076 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 7,578E-03 0,02301117 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 7,578E-03 0,02299162 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 7,578E-03 0,02297211 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 7,578E-03 0,02295262 ! titin binding GO:0031432 8 8 0,000 7,578E-03 0,02293317 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 7,578E-03 0,02291375 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 7,578E-03 0,02289437 ! bone resorption GO:0045453 8 8 0,000 7,578E-03 0,02287501 ! glycerolipid catabolic process GO:0046503 8 8 0,000 7,578E-03 0,02285569 ! endoderm development GO:0007492 8 8 0,000 7,578E-03 0,02283641 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 7,578E-03 0,02281715 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 7,578E-03 0,02279793 ! astrocyte differentiation GO:0048708 8 8 0,000 7,578E-03 0,02277874 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 7,578E-03 0,02275958 ! syncytium formation GO:0006949 8 8 0,000 7,578E-03 0,02274045 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 7,578E-03 0,02272136 ! B cell proliferation GO:0042100 8 8 0,000 7,578E-03 0,0227023 ! mannose metabolic process GO:0006013 10 8 0,000 7,578E-03 0,02268327 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 7,578E-03 0,02266427 ! asymmetric protein localization GO:0008105 8 8 0,000 7,578E-03 0,02264531 ! tumor necrosis factor binding GO:0043120 8 8 0,000 7,578E-03 0,02262637 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 7,578E-03 0,02260747 ! neuron apoptosis GO:0051402 8 8 0,000 7,578E-03 0,0225886 ! macroautophagy GO:0016236 9 8 0,000 7,578E-03 0,02256976 ! Cajal body GO:0015030 8 8 0,000 7,578E-03 0,02255095 ! O-methyltransferase activity GO:0008171 9 8 0,000 7,578E-03 0,02253217 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 7,578E-03 0,02251343 ! PcG protein complex GO:0031519 8 8 0,000 7,578E-03 0,02249471 ! ferric iron binding GO:0008199 9 8 0,000 7,578E-03 0,02247603 ! spindle checkpoint GO:0031577 8 8 0,000 7,578E-03 0,02245738 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 7,578E-03 0,02243876 ! segment specification GO:0007379 8 8 0,000 7,578E-03 0,02242017 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 7,578E-03 0,02240161 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 7,578E-03 0,02238308 ! cellular extravasation GO:0045123 9 8 0,000 7,578E-03 0,02236458 ! pronucleus GO:0045120 8 8 0,000 7,578E-03 0,02234611 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 7,578E-03 0,02232767 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 7,578E-03 0,02230927 ! Rac GTPase activator activity GO:0030675 9 8 0,000 7,578E-03 0,02229089 ! regulation of DNA repair GO:0006282 8 8 0,000 7,578E-03 0,02227254 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 7,578E-03 0,02225423 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 7,578E-03 0,02223594 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 7,578E-03 0,02221768 ! DNA ligation GO:0006266 8 8 0,000 7,578E-03 0,02219946 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 7,578E-03 0,02218126 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 7,578E-03 0,0221631 ! multicellular organismal aging GO:0010259 8 8 0,000 7,578E-03 0,02214496 ! erythrocyte development GO:0048821 8 8 0,000 7,578E-03 0,02212685 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 7,578E-03 0,02210877 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 7,578E-03 0,02209073 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 7,578E-03 0,02207271 ! gamma-tubulin binding GO:0043015 8 8 0,000 7,578E-03 0,02205472 ! ribosome binding GO:0043022 9 8 0,000 7,578E-03 0,02203676 ! NADPH oxidase complex GO:0043020 8 8 0,000 7,578E-03 0,02201883 ! mRNA polyadenylation GO:0006378 8 8 0,000 7,578E-03 0,02200093 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 7,578E-03 0,02198305 ! adenylyltransferase activity GO:0070566 8 8 0,000 7,578E-03 0,02196521 ! zymogen activation GO:0031638 8 8 0,000 7,578E-03 0,0219474 ! axonal fasciculation GO:0007413 8 8 0,000 7,578E-03 0,02192961 ! T cell homeostasis GO:0043029 9 8 0,000 7,578E-03 0,02191185 ! negative regulation of nuclear division GO:0051784 8 8 0,000 7,578E-03 0,02189413 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 7,578E-03 0,02187643 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 7,578E-03 0,02185876 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 7,578E-03 0,02184111 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 7,578E-03 0,0218235 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 7,578E-03 0,02180591 ! wide pore channel activity GO:0022829 8 8 0,000 7,578E-03 0,02178836 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 7,578E-03 0,02177083 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 7,578E-03 0,02175333 ! hormone catabolic process GO:0042447 8 8 0,000 7,578E-03 0,02173586 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 7,578E-03 0,02171841 ! biogenic amine catabolic process GO:0042402 11 8 0,000 7,578E-03 0,02170099 ! Notch binding GO:0005112 8 8 0,000 7,578E-03 0,02168361 ! death receptor binding GO:0005123 8 8 0,000 7,578E-03 0,02166624 ! ATPase regulator activity GO:0060590 8 8 0,000 7,578E-03 0,02164891 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 7,578E-03 0,02163161 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 7,578E-03 0,02161433 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 7,578E-03 0,02159708 ! calcium-release channel activity GO:0015278 8 8 0,000 7,578E-03 0,02157986 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 7,578E-03 0,02156266 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 7,578E-03 0,02154549 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 0,000 7,578E-03 0,02152835 ! nucleus localization GO:0051647 10 8 0,000 7,578E-03 0,02151124 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 7,578E-03 0,02149415 ! negative regulation of immune effector process GO:0002698 12 8 0,000 7,578E-03 0,0214771 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 7,578E-03 0,02146006 ! adenosine deaminase activity GO:0004000 8 8 0,000 7,578E-03 0,02144306 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 8,522E-03 0,02409371 ! respiratory burst GO:0045730 9 9 0,000 8,522E-03 0,02407465 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 0,000 8,522E-03 0,02405562 ! telencephalon cell migration GO:0022029 9 9 0,000 8,522E-03 0,02403662 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 8,522E-03 0,02401765 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 8,522E-03 0,02399871 ! cGMP metabolic process GO:0046068 9 9 0,000 8,522E-03 0,0239798 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 8,522E-03 0,02396091 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 8,522E-03 0,02394206 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 8,522E-03 0,02392324 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 8,522E-03 0,02390445 ! RNA polyadenylation GO:0043631 9 9 0,000 8,522E-03 0,02388568 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 8,522E-03 0,02386695 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 8,522E-03 0,02384825 ! artery development GO:0060840 9 9 0,000 8,522E-03 0,02382957 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 8,522E-03 0,02381092 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 8,522E-03 0,02379231 ! middle ear morphogenesis GO:0042474 9 9 0,000 8,522E-03 0,02377372 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 8,522E-03 0,02375516 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 8,522E-03 0,02373663 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 8,522E-03 0,02371813 ! lung alveolus development GO:0048286 9 9 0,000 8,522E-03 0,02369966 ! ciliary or flagellar motility GO:0001539 9 9 0,000 8,522E-03 0,02368121 ! beta-amyloid binding GO:0001540 10 9 0,000 8,522E-03 0,0236628 ! pathogenesis GO:0009405 9 9 0,000 8,522E-03 0,02364441 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 8,522E-03 0,02362606 ! regulated secretory pathway GO:0045055 9 9 0,000 8,522E-03 0,02360773 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 8,522E-03 0,02358943 ! estrogen receptor binding GO:0030331 9 9 0,000 8,522E-03 0,02357115 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 8,522E-03 0,02355291 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 8,522E-03 0,0235347 ! histidine metabolic process GO:0006547 9 9 0,000 8,522E-03 0,02351651 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 8,522E-03 0,02349835 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 8,522E-03 0,02348022 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 8,522E-03 0,02346211 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 8,522E-03 0,02344404 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 8,522E-03 0,02342599 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 8,522E-03 0,02340797 ! entry into host cell GO:0030260 9 9 0,000 8,522E-03 0,02338998 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 8,522E-03 0,02337201 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 8,522E-03 0,02335408 ! retinoic acid metabolic process GO:0042573 9 9 0,000 8,522E-03 0,02333617 ! retinol metabolic process GO:0042572 9 9 0,000 8,522E-03 0,02331828 ! behavioral fear response GO:0001662 9 9 0,000 8,522E-03 0,02330043 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 8,522E-03 0,0232826 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 8,522E-03 0,0232648 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 8,522E-03 0,02324703 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 8,522E-03 0,02322928 ! regulation of gliogenesis GO:0014013 9 9 0,000 8,522E-03 0,02321156 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 8,522E-03 0,02319387 ! pigment granule localization GO:0051875 9 9 0,000 8,522E-03 0,02317621 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 8,522E-03 0,02315857 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 8,522E-03 0,02314096 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 8,522E-03 0,02312337 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 8,522E-03 0,02310582 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 8,522E-03 0,02308829 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 8,522E-03 0,02307078 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 8,522E-03 0,0230533 ! nitric oxide metabolic process GO:0046209 9 9 0,000 8,522E-03 0,02303585 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 8,522E-03 0,02301843 ! icosanoid secretion GO:0032309 9 9 0,000 8,522E-03 0,02300103 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 8,522E-03 0,02298366 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 8,522E-03 0,02296631 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 8,522E-03 0,02294899 ! sterol catabolic process GO:0016127 9 9 0,000 8,522E-03 0,0229317 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 8,522E-03 0,02291443 ! peptidyl-lysine modification GO:0018205 9 9 0,000 8,522E-03 0,02289719 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 8,522E-03 0,02287997 ! clathrin coat of coated pit GO:0030132 12 9 0,000 8,522E-03 0,02286278 ! SNARE complex GO:0031201 10 9 0,000 8,522E-03 0,02284562 ! ubiquinone metabolic process GO:0006743 10 9 0,000 8,522E-03 0,02282848 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 8,522E-03 0,02281136 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 8,522E-03 0,02279428 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 8,522E-03 0,02277722 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 8,522E-03 0,02276018 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 8,522E-03 0,02274317 ! methionine biosynthetic process GO:0009086 10 9 0,000 8,522E-03 0,02272618 ! peptidoglycan binding GO:0042834 9 9 0,000 8,522E-03 0,02270922 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 8,522E-03 0,02269229 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 8,522E-03 0,02267538 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 8,522E-03 0,0226585 ! cholesterol efflux GO:0033344 9 9 0,000 8,522E-03 0,02264164 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 8,522E-03 0,0226248 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 8,522E-03 0,02260799 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 8,522E-03 0,02259121 ! anterior/posterior axis specification GO:0009948 9 9 0,000 8,522E-03 0,02257445 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 8,522E-03 0,02255772 ! detection of calcium ion GO:0005513 10 9 0,000 8,522E-03 0,02254101 ! negative regulation of glucose import GO:0046325 9 9 0,000 8,522E-03 0,02252432 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 8,522E-03 0,02250766 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 8,522E-03 0,02249103 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 8,522E-03 0,02247442 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 8,522E-03 0,02245783 ! desmosome GO:0030057 9 9 0,000 8,522E-03 0,02244127 ! prepulse inhibition GO:0060134 9 9 0,000 8,522E-03 0,02242473 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 8,522E-03 0,02240822 ! negative regulation of B cell activation GO:0050869 9 9 0,000 8,522E-03 0,02239173 ! anchoring collagen GO:0030934 9 9 0,000 8,522E-03 0,02237527 ! axon extension GO:0048675 10 9 0,000 8,522E-03 0,02235882 ! neuron fate specification GO:0048665 9 9 0,000 8,522E-03 0,02234241 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 8,522E-03 0,02232602 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 8,522E-03 0,02230965 ! virus-host interaction GO:0019048 13 9 0,000 8,522E-03 0,0222933 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 8,522E-03 0,02227698 ! pentose-phosphate shunt GO:0006098 9 9 0,000 8,522E-03 0,02226069 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 8,522E-03 0,02224442 ! DNA bending activity GO:0008301 9 9 0,000 8,522E-03 0,02222817 ! social behavior GO:0035176 9 9 0,000 8,522E-03 0,02221194 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 8,522E-03 0,02219574 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 8,522E-03 0,02217956 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 8,522E-03 0,02216341 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 8,522E-03 0,02214728 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 8,522E-03 0,02213117 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 8,522E-03 0,02211509 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 8,522E-03 0,02209903 ! blood vessel remodeling GO:0001974 10 9 0,000 8,522E-03 0,02208299 ! C-X-C chemokine binding GO:0019958 9 9 0,000 8,522E-03 0,02206698 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 8,522E-03 0,02205099 ! exosome (RNase complex) GO:0000178 9 9 0,000 8,522E-03 0,02203502 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 8,522E-03 0,02201907 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 8,522E-03 0,02200315 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 8,522E-03 0,02198725 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 8,522E-03 0,02197138 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 8,522E-03 0,02195553 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 8,522E-03 0,0219397 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 8,522E-03 0,02192389 ! phagocytosis, engulfment GO:0006911 10 9 0,000 8,522E-03 0,02190811 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 8,522E-03 0,02189235 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 8,522E-03 0,02187661 ! glutathione peroxidase activity GO:0004602 9 9 0,000 8,522E-03 0,02186089 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 8,522E-03 0,0218452 ! lysophospholipase activity GO:0004622 9 9 0,000 8,522E-03 0,02182953 ! brain morphogenesis GO:0048854 9 9 0,000 8,522E-03 0,02181388 ! apolipoprotein binding GO:0034185 9 9 0,000 8,522E-03 0,02179825 ! synaptic vesicle membrane GO:0030672 9 9 0,000 8,522E-03 0,02178265 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 8,522E-03 0,02176707 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 8,522E-03 0,02175151 ! kinesin binding GO:0019894 9 9 0,000 8,522E-03 0,02173597 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 8,522E-03 0,02172046 ! renal water homeostasis GO:0003091 9 9 0,000 8,522E-03 0,02170496 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 8,522E-03 0,02168949 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 8,522E-03 0,02167405 ! histone methylation GO:0016571 10 9 0,000 8,522E-03 0,02165862 ! mRNA cleavage GO:0006379 9 9 0,000 8,522E-03 0,02164322 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 8,522E-03 0,02162783 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 8,522E-03 0,02161247 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 8,522E-03 0,02159713 ! opioid receptor activity GO:0004985 9 9 0,000 8,522E-03 0,02158182 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 8,522E-03 0,02156652 ! salivary gland development GO:0007431 10 9 0,000 8,522E-03 0,02155125 ! glucosidase activity GO:0015926 10 9 0,000 8,522E-03 0,02153599 ! adrenoceptor activity GO:0004935 11 9 0,000 8,522E-03 0,02152076 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 8,522E-03 0,02150556 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 8,522E-03 0,02149037 ! purine base metabolic process GO:0006144 11 9 0,000 8,522E-03 0,0214752 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 8,522E-03 0,02146006 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 8,522E-03 0,02144493 ! receptor inhibitor activity GO:0030547 9 9 0,000 8,522E-03 0,02142983 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 8,522E-03 0,02141475 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 8,522E-03 0,02139969 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 8,522E-03 0,02138465 ! palmitoyltransferase activity GO:0016409 9 9 0,000 8,522E-03 0,02136964 ! arylsulfatase activity GO:0004065 9 9 0,000 8,522E-03 0,02135464 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 8,522E-03 0,02133966 ! behavioral response to nicotine GO:0035095 9 9 0,000 8,522E-03 0,02132471 ! adenylate kinase activity GO:0004017 10 9 0,000 8,522E-03 0,02130978 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 8,522E-03 0,02129486 ! mitochondrion localization GO:0051646 9 9 0,000 8,522E-03 0,02127997 ! localization within membrane GO:0051668 9 9 0,000 8,522E-03 0,0212651 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 9,464E-03 0,02360098 ! lipid particle GO:0005811 10 10 0,000 9,464E-03 0,02358451 ! myotube differentiation GO:0014902 10 10 0,000 9,464E-03 0,02356807 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 9,464E-03 0,02355164 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 9,464E-03 0,02353524 ! synapsis GO:0007129 10 10 0,000 9,464E-03 0,02351886 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 9,464E-03 0,02350251 ! UTP metabolic process GO:0046051 10 10 0,000 9,464E-03 0,02348618 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 9,464E-03 0,02346987 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 9,464E-03 0,02345358 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 9,464E-03 0,02343731 ! platelet alpha granule membrane GO:0031092 11 10 0,000 9,464E-03 0,02342107 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 9,464E-03 0,02340485 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 9,464E-03 0,02338866 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 9,464E-03 0,02337248 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 9,464E-03 0,02335633 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 9,464E-03 0,0233402 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 9,464E-03 0,02332409 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 9,464E-03 0,023308 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 9,464E-03 0,02329194 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 9,464E-03 0,0232759 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 9,464E-03 0,02325988 ! melanocyte differentiation GO:0030318 10 10 0,000 9,464E-03 0,02324388 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 9,464E-03 0,02322791 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 9,464E-03 0,02321196 ! L-serine metabolic process GO:0006563 11 10 0,000 9,464E-03 0,02319602 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 9,464E-03 0,02318011 ! lipase inhibitor activity GO:0055102 10 10 0,000 9,464E-03 0,02316423 ! autophagic vacuole GO:0005776 11 10 0,000 9,464E-03 0,02314836 ! NAD metabolic process GO:0019674 10 10 0,000 9,464E-03 0,02313252 ! stereocilium GO:0032420 10 10 0,000 9,464E-03 0,02311669 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 9,464E-03 0,02310089 ! regulation of sodium ion transport GO:0002028 10 10 0,000 9,464E-03 0,02308511 ! forebrain cell migration GO:0021885 10 10 0,000 9,464E-03 0,02306936 ! organelle subcompartment GO:0031984 11 10 0,000 9,464E-03 0,02305362 ! chondrocyte differentiation GO:0002062 10 10 0,000 9,464E-03 0,02303791 ! negative regulation of ossification GO:0030279 10 10 0,000 9,464E-03 0,02302221 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 9,464E-03 0,02300654 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 9,464E-03 0,02299089 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 9,464E-03 0,02297526 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 9,464E-03 0,02295965 ! protein homotetramerization GO:0051289 11 10 0,000 9,464E-03 0,02294406 ! oligodendrocyte development GO:0014003 10 10 0,000 9,464E-03 0,0229285 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 9,464E-03 0,02291295 ! response to dsRNA GO:0043331 10 10 0,000 9,464E-03 0,02289743 ! mismatch repair complex binding GO:0032404 11 10 0,000 9,464E-03 0,02288193 ! snRNA metabolic process GO:0016073 10 10 0,000 9,464E-03 0,02286645 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 9,464E-03 0,02285099 ! fucose catabolic process GO:0019317 11 10 0,000 9,464E-03 0,02283555 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 9,464E-03 0,02282013 ! retinal binding GO:0016918 10 10 0,000 9,464E-03 0,02280473 ! leukocyte activation during immune response GO:0002366 10 10 0,000 9,464E-03 0,02278935 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 9,464E-03 0,02277399 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 9,464E-03 0,02275866 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 9,464E-03 0,02274334 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 9,464E-03 0,02272805 ! ribonuclease P activity GO:0004526 10 10 0,000 9,464E-03 0,02271277 ! midbrain development GO:0030901 10 10 0,000 9,464E-03 0,02269752 ! musculoskeletal movement GO:0050881 10 10 0,000 9,464E-03 0,02268229 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 9,464E-03 0,02266707 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 9,464E-03 0,02265188 ! fatty-acid ligase activity GO:0015645 10 10 0,000 9,464E-03 0,02263671 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 9,464E-03 0,02262156 ! quaternary ammonium group transport GO:0015697 10 10 0,000 9,464E-03 0,02260643 ! regulation of RNA splicing GO:0043484 10 10 0,000 9,464E-03 0,02259131 ! embryonic gut development GO:0048566 10 10 0,000 9,464E-03 0,02257622 ! positive regulation of amine transport GO:0051954 10 10 0,000 9,464E-03 0,02256115 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 9,464E-03 0,0225461 ! mRNA 3'-end processing GO:0031124 10 10 0,000 9,464E-03 0,02253107 ! lysogeny GO:0030069 10 10 0,000 9,464E-03 0,02251606 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 9,464E-03 0,02250107 ! establishment of cell polarity GO:0030010 10 10 0,000 9,464E-03 0,0224861 ! regulation of synapse organization GO:0050807 10 10 0,000 9,464E-03 0,02247115 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 9,464E-03 0,02245622 ! acyl-CoA binding GO:0000062 10 10 0,000 9,464E-03 0,02244131 ! negative regulation of muscle development GO:0048635 11 10 0,000 9,464E-03 0,02242641 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 9,464E-03 0,02241154 ! GDP binding GO:0019003 10 10 0,000 9,464E-03 0,02239669 ! photoreceptor activity GO:0009881 10 10 0,000 9,464E-03 0,02238186 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 9,464E-03 0,02236705 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 9,464E-03 0,02235225 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 9,464E-03 0,02233748 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 9,464E-03 0,02232273 ! nucleotidase activity GO:0008252 10 10 0,000 9,464E-03 0,02230799 ! protein complex disassembly GO:0043241 11 10 0,000 9,464E-03 0,02229328 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 9,464E-03 0,02227858 ! lateral plasma membrane GO:0016328 10 10 0,000 9,464E-03 0,0222639 ! estrogen metabolic process GO:0008210 10 10 0,000 9,464E-03 0,02224925 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 9,464E-03 0,02223461 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 9,464E-03 0,02221999 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 9,464E-03 0,02220539 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 9,464E-03 0,02219081 ! interleukin-1 binding GO:0019966 10 10 0,000 9,464E-03 0,02217625 ! endothelial cell differentiation GO:0045446 10 10 0,000 9,464E-03 0,02216171 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 9,464E-03 0,02214719 ! acid phosphatase activity GO:0003993 10 10 0,000 9,464E-03 0,02213268 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 9,464E-03 0,0221182 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 9,464E-03 0,02210373 ! telomeric DNA binding GO:0042162 11 10 0,000 9,464E-03 0,02208929 ! regulation of intracellular pH GO:0051453 10 10 0,000 9,464E-03 0,02207486 ! lipid digestion GO:0044241 10 10 0,000 9,464E-03 0,02206045 ! multicellular organism growth GO:0035264 10 10 0,000 9,464E-03 0,02204606 ! receptor clustering GO:0043113 10 10 0,000 9,464E-03 0,02203169 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 9,464E-03 0,02201733 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 9,464E-03 0,022003 ! adult heart development GO:0007512 12 10 0,000 9,464E-03 0,02198868 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 9,464E-03 0,02197439 ! signalosome GO:0008180 10 10 0,000 9,464E-03 0,02196011 ! prefoldin complex GO:0016272 10 10 0,000 9,464E-03 0,02194585 ! neuromuscular junction GO:0031594 10 10 0,000 9,464E-03 0,02193161 ! regulation of bone resorption GO:0045124 11 10 0,000 9,464E-03 0,02191738 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 9,464E-03 0,02190318 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 9,464E-03 0,02188899 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 9,464E-03 0,02187483 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 9,464E-03 0,02186068 ! taste receptor activity GO:0008527 10 10 0,000 9,464E-03 0,02184655 ! Ran GTPase binding GO:0008536 10 10 0,000 9,464E-03 0,02183243 ! endocytic vesicle membrane GO:0030666 10 10 0,000 9,464E-03 0,02181834 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 9,464E-03 0,02180426 ! ribosome assembly GO:0042255 10 10 0,000 9,464E-03 0,0217902 ! DNA methylation GO:0006306 12 10 0,000 9,464E-03 0,02177616 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 9,464E-03 0,02176214 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 9,464E-03 0,02174814 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 9,464E-03 0,02173415 ! prostaglandin receptor activity GO:0004955 11 10 0,000 9,464E-03 0,02172018 ! regulation of isotype switching GO:0045191 14 10 0,000 9,464E-03 0,02170623 ! peptide transporter activity GO:0015197 10 10 0,000 9,464E-03 0,0216923 ! regulation of leukocyte migration GO:0002685 10 10 0,000 9,464E-03 0,02167839 ! retinoid-X receptor activity GO:0004886 10 10 0,000 9,464E-03 0,02166449 ! GTPase inhibitor activity GO:0005095 10 10 0,000 9,464E-03 0,02165061 ! pattern recognition receptor activity GO:0008329 10 10 0,000 9,464E-03 0,02163675 ! gamma-tubulin complex GO:0000930 12 10 0,000 9,464E-03 0,02162291 ! germ cell migration GO:0008354 10 10 0,000 9,464E-03 0,02160908 ! regulation of organic acid transport GO:0032890 10 10 0,000 9,464E-03 0,02159528 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 9,464E-03 0,02158149 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 9,464E-03 0,02156771 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 9,464E-03 0,02155396 ! sterol transporter activity GO:0015248 10 10 0,000 9,464E-03 0,02154022 ! regulation of embryonic development GO:0045995 11 10 0,000 9,464E-03 0,0215265 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 0,01040602 0,02365365 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 0,01040602 0,0236386 ! negative regulation of blood pressure GO:0045776 11 11 0,000 0,01040602 0,02362357 ! RNA cap binding GO:0000339 12 11 0,000 0,01040602 0,02360856 ! CTP metabolic process GO:0046036 12 11 0,000 0,01040602 0,02359358 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 0,01040602 0,0235786 ! response to pain GO:0048265 11 11 0,000 0,01040602 0,02356365 ! axonemal dynein complex GO:0005858 11 11 0,000 0,01040602 0,02354872 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 0,01040602 0,02353381 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 0,01040602 0,02351891 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 0,01040602 0,02350404 ! endocrine pancreas development GO:0031018 11 11 0,000 0,01040602 0,02348918 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 0,01040602 0,02347434 ! regulation of exit from mitosis GO:0007096 11 11 0,000 0,01040602 0,02345952 ! chylomicron GO:0042627 11 11 0,000 0,01040602 0,02344472 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 0,01040602 0,02342994 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 0,01040602 0,02341517 ! transforming growth factor beta binding GO:0050431 11 11 0,000 0,01040602 0,02340043 ! glutamate metabolic process GO:0006536 12 11 0,000 0,01040602 0,0233857 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 0,01040602 0,02337099 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01040602 0,0233563 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 0,01040602 0,02334163 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 0,01040602 0,02332698 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 0,01040602 0,02331235 ! epithelial cell development GO:0002064 11 11 0,000 0,01040602 0,02329773 ! filamentous actin GO:0031941 11 11 0,000 0,01040602 0,02328313 ! temperature homeostasis GO:0001659 11 11 0,000 0,01040602 0,02326855 ! structural constituent of epidermis GO:0030280 13 11 0,000 0,01040602 0,02325399 ! protein targeting to peroxisome GO:0006625 11 11 0,000 0,01040602 0,02323945 ! spectrin GO:0008091 11 11 0,000 0,01040602 0,02322493 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 0,01040602 0,02321042 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 0,01040602 0,02319593 ! regulation of phagocytosis GO:0050764 11 11 0,000 0,01040602 0,02318146 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 0,01040602 0,02316701 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 0,01040602 0,02315257 ! regulation of B cell differentiation GO:0045577 15 11 0,000 0,01040602 0,02313816 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 0,01040602 0,02312376 ! basal lamina GO:0005605 12 11 0,000 0,01040602 0,02310938 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 0,01040602 0,02309502 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 0,01040602 0,02308067 ! hindbrain morphogenesis GO:0021575 13 11 0,000 0,01040602 0,02306634 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 0,01040602 0,02305204 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 0,01040602 0,02303774 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 0,01040602 0,02302347 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 0,01040602 0,02300921 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 0,01040602 0,02299498 ! cofactor transporter activity GO:0051184 11 11 0,000 0,01040602 0,02298076 ! cobalt ion binding GO:0050897 11 11 0,000 0,01040602 0,02296655 ! pseudouridine synthase activity GO:0009982 12 11 0,000 0,01040602 0,02295237 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 0,01040602 0,0229382 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 0,01040602 0,02292405 ! histone deacetylase binding GO:0042826 11 11 0,000 0,01040602 0,02290991 ! thymus development GO:0048538 12 11 0,000 0,01040602 0,0228958 ! spleen development GO:0048536 12 11 0,000 0,01040602 0,0228817 ! regulation of RNA stability GO:0043487 11 11 0,000 0,01040602 0,02286762 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 0,01040602 0,02285356 ! acid-thiol ligase activity GO:0016878 11 11 0,000 0,01040602 0,02283951 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 0,01040602 0,02282548 ! blastocyst formation GO:0001825 11 11 0,000 0,01040602 0,02281147 ! cerebellar cortex development GO:0021695 12 11 0,000 0,01040602 0,02279747 ! ADP binding GO:0043531 11 11 0,000 0,01040602 0,0227835 ! folic acid binding GO:0005542 11 11 0,000 0,01040602 0,02276953 ! FK506 binding GO:0005528 11 11 0,000 0,01040602 0,02275559 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 0,01040602 0,02274167 ! extracellular matrix binding GO:0050840 13 11 0,000 0,01040602 0,02272776 ! microspike assembly GO:0030035 13 11 0,000 0,01040602 0,02271386 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 0,01040602 0,02269999 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 0,01040602 0,02268613 ! organ formation GO:0048645 12 11 0,000 0,01040602 0,02267229 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01040602 0,02265846 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 0,01040602 0,02264466 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 0,01040602 0,02263087 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 0,01040602 0,02261709 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 0,01040602 0,02260333 ! Golgi vesicle budding GO:0048194 11 11 0,000 0,01040602 0,02258959 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 0,01040602 0,02257587 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01040602 0,02256216 ! ion channel inhibitor activity GO:0008200 13 11 0,000 0,01040602 0,02254847 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 0,01040602 0,0225348 ! MAP kinase kinase activity GO:0004708 11 11 0,000 0,01040602 0,02252114 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 0,01040602 0,0225075 ! mannosyltransferase activity GO:0000030 11 11 0,000 0,01040602 0,02249387 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 0,01040602 0,02248027 ! FMN binding GO:0010181 11 11 0,000 0,01040602 0,02246668 ! response to X-ray GO:0010165 12 11 0,000 0,01040602 0,0224531 ! focal adhesion formation GO:0048041 13 11 0,000 0,01040602 0,02243954 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 0,01040602 0,022426 ! integrator complex GO:0032039 11 11 0,000 0,01040602 0,02241247 ! UV protection GO:0009650 11 11 0,000 0,01040602 0,02239896 ! L-glutamate transport GO:0015813 11 11 0,000 0,01040602 0,02238547 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 0,01040602 0,02237199 ! regulation of organ growth GO:0046620 12 11 0,000 0,01040602 0,02235853 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 0,01040602 0,02234509 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 0,01040602 0,02233166 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 0,01040602 0,02231825 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 0,01040602 0,02230485 ! histone acetylation GO:0016573 11 11 0,000 0,01040602 0,02229147 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 0,01040602 0,02227811 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 0,01040602 0,02226476 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 0,01040602 0,02225143 ! chromatin silencing GO:0006342 11 11 0,000 0,01040602 0,02223811 ! gland morphogenesis GO:0022612 12 11 0,000 0,01040602 0,02222481 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 0,01040602 0,02221152 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 0,01040602 0,02219826 ! icosanoid receptor activity GO:0004953 12 11 0,000 0,01040602 0,022185 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 0,01040602 0,02217177 ! negative regulation of neurological system process GO:0031645 12 11 0,000 0,01040602 0,02215855 ! acid secretion GO:0046717 11 11 0,000 0,01040602 0,02214534 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 0,01040602 0,02213215 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 0,01040602 0,02211898 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 0,01040602 0,02210582 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 0,01040602 0,02209268 ! midbody GO:0030496 11 11 0,000 0,01040602 0,02207955 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 0,01040602 0,02206644 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 0,01040602 0,02205334 ! water channel activity GO:0015250 11 11 0,000 0,01040602 0,02204026 ! response to nicotine GO:0035094 11 11 0,000 0,01040602 0,0220272 ! response to cold GO:0009409 11 11 0,000 0,01040602 0,02201415 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01040602 0,02200111 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01134701 0,02397644 ! centriole GO:0005814 12 12 0,000 0,01134701 0,02396226 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01134701 0,0239481 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01134701 0,02393395 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01134701 0,02391983 ! bone remodeling GO:0046849 12 12 0,000 0,01134701 0,02390571 ! peroxisomal transport GO:0043574 12 12 0,000 0,01134701 0,02389162 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01134701 0,02387754 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01134701 0,02386348 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01134701 0,02384943 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01134701 0,0238354 ! hippocampus development GO:0021766 12 12 0,000 0,01134701 0,02382139 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 0,01134701 0,02380739 ! T cell selection GO:0045058 16 12 0,000 0,01134701 0,02379341 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01134701 0,02377945 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01134701 0,0237655 ! T-tubule GO:0030315 13 12 0,000 0,01134701 0,02375157 ! methionine metabolic process GO:0006555 13 12 0,000 0,01134701 0,02373766 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01134701 0,02372376 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01134701 0,02370988 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01134701 0,02369601 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01134701 0,02368217 ! mitotic spindle organization GO:0007052 12 12 0,000 0,01134701 0,02366833 ! fear response GO:0042596 12 12 0,000 0,01134701 0,02365452 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01134701 0,02364071 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01134701 0,02362693 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01134701 0,02361316 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01134701 0,02359941 ! axon cargo transport GO:0008088 12 12 0,000 0,01134701 0,02358567 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01134701 0,02357195 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01134701 0,02355825 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01134701 0,02354456 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01134701 0,02353089 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01134701 0,02351723 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01134701 0,02350359 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01134701 0,02348996 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01134701 0,02347635 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01134701 0,02346276 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01134701 0,02344918 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01134701 0,02343562 ! cell killing GO:0001906 12 12 0,000 0,01134701 0,02342207 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01134701 0,02340854 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01134701 0,02339503 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01134701 0,02338153 ! detection of bacterium GO:0016045 13 12 0,000 0,01134701 0,02336804 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01134701 0,02335457 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01134701 0,02334112 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01134701 0,02332768 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01134701 0,02331426 ! developmental induction GO:0031128 13 12 0,000 0,01134701 0,02330085 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01134701 0,02328746 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01134701 0,02327409 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01134701 0,02326073 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01134701 0,02324738 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01134701 0,02323405 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01134701 0,02322074 ! thyroid gland development GO:0030878 12 12 0,000 0,01134701 0,02320744 ! non-recombinational repair GO:0000726 12 12 0,000 0,01134701 0,02319415 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01134701 0,02318088 ! lipid localization GO:0010876 12 12 0,000 0,01134701 0,02316763 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01134701 0,02315439 ! response to cAMP GO:0051591 12 12 0,000 0,01134701 0,02314117 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01134701 0,02312796 ! T cell proliferation GO:0042098 17 12 0,000 0,01134701 0,02311477 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01134701 0,02310159 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01134701 0,02308842 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01134701 0,02307528 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01134701 0,02306214 ! drug transport GO:0015893 12 12 0,000 0,01134701 0,02304902 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01134701 0,02303592 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01134701 0,02302283 ! T cell receptor complex GO:0042101 12 12 0,000 0,01134701 0,02300976 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01134701 0,0229967 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 0,01134701 0,02298366 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01134701 0,02297063 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01134701 0,02295761 ! dendritic spine GO:0043197 12 12 0,000 0,01134701 0,02294461 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01134701 0,02293163 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01134701 0,02291866 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01134701 0,0229057 ! vasoconstriction GO:0042310 13 12 0,000 0,01134701 0,02289276 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01134701 0,02287983 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01134701 0,02286692 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01134701 0,02285402 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01134701 0,02284114 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01134701 0,02282827 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01134701 0,02281542 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01134701 0,02280258 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01134701 0,02278976 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01134701 0,02277695 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01134701 0,02276415 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01134701 0,02275137 ! protein kinase C binding GO:0005080 13 12 0,000 0,01134701 0,0227386 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01134701 0,02272585 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01134701 0,02271311 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 0,01134701 0,02270038 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01134701 0,02268767 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01134701 0,02267498 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01134701 0,0226623 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01134701 0,02264963 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01134701 0,02263698 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01134701 0,02262434 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01134701 0,02261171 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 0,01134701 0,0225991 ! positive regulation of translation GO:0045727 13 13 0,000 0,01228718 0,02445793 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01228718 0,0244443 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01228718 0,02443069 ! superoxide anion generation GO:0042554 13 13 0,000 0,01228718 0,0244171 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01228718 0,02440352 ! cis-Golgi network GO:0005801 14 13 0,000 0,01228718 0,02438995 ! regulation of S phase GO:0033261 17 13 0,000 0,01228718 0,0243764 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01228718 0,02436287 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01228718 0,02434935 ! endothelial cell migration GO:0043542 13 13 0,000 0,01228718 0,02433584 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01228718 0,02432235 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01228718 0,02430888 ! organelle fusion GO:0048284 14 13 0,000 0,01228718 0,02429542 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01228718 0,02428197 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01228718 0,02426854 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01228718 0,02425513 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01228718 0,02424173 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01228718 0,02422834 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01228718 0,02421497 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01228718 0,02420161 ! arginine metabolic process GO:0006525 13 13 0,000 0,01228718 0,02418827 ! WW domain binding GO:0050699 14 13 0,000 0,01228718 0,02417494 ! cholesterol binding GO:0015485 13 13 0,000 0,01228718 0,02416163 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01228718 0,02414833 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01228718 0,02413505 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01228718 0,02412178 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01228718 0,02410853 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01228718 0,02409529 ! regulation of heart rate GO:0002027 14 13 0,000 0,01228718 0,02408207 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01228718 0,02406885 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01228718 0,02405566 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01228718 0,02404248 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01228718 0,02402931 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01228718 0,02401616 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01228718 0,02400302 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01228718 0,0239899 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01228718 0,02397679 ! NADP metabolic process GO:0006739 13 13 0,000 0,01228718 0,02396369 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01228718 0,02395061 ! intestinal absorption GO:0050892 13 13 0,000 0,01228718 0,02393755 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01228718 0,02392449 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01228718 0,02391146 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01228718 0,02389843 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01228718 0,02388542 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01228718 0,02387243 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01228718 0,02385945 ! embryonic placenta development GO:0001892 13 13 0,000 0,01228718 0,02384648 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01228718 0,02383353 ! insulin secretion GO:0030073 13 13 0,000 0,01228718 0,02382059 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01228718 0,02380766 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01228718 0,02379475 ! replisome GO:0030894 14 13 0,000 0,01228718 0,02378186 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01228718 0,02376897 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01228718 0,0237561 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01228718 0,02374325 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01228718 0,02373041 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01228718 0,02371758 ! mating GO:0007618 13 13 0,000 0,01228718 0,02370477 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01228718 0,02369197 ! MAP kinase activity GO:0004707 14 13 0,000 0,01228718 0,02367918 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01228718 0,02366641 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01228718 0,02365365 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01228718 0,02364091 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01228718 0,02362818 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01228718 0,02361546 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01228718 0,02360276 ! protein kinase C activity GO:0004697 15 13 0,000 0,01228718 0,02359007 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01228718 0,02357739 ! water transporter activity GO:0005372 13 13 0,000 0,01228718 0,02356473 ! exocrine system development GO:0035272 14 13 0,000 0,01228718 0,02355208 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01228718 0,02353944 ! monoamine transport GO:0015844 13 13 0,000 0,01228718 0,02352682 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01228718 0,02351421 ! embryo implantation GO:0007566 13 13 0,000 0,01228718 0,02350162 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01228718 0,02348904 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01228718 0,02347647 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01228718 0,02346392 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01228718 0,02345137 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01228718 0,02343885 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01228718 0,02342633 ! histone deacetylation GO:0016575 13 13 0,000 0,01228718 0,02341383 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01228718 0,02340135 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01228718 0,02338887 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01228718 0,02337641 ! response to gamma radiation GO:0010332 13 13 0,000 0,01228718 0,02336396 ! sarcomere organization GO:0045214 13 13 0,000 0,01228718 0,02335153 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01228718 0,02333911 ! cAMP binding GO:0030552 13 13 0,000 0,01228718 0,0233267 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01228718 0,02331431 ! cilium assembly GO:0042384 13 13 0,000 0,01228718 0,02330192 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01228718 0,02328956 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01228718 0,0232772 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01228718 0,02326486 ! acrosome reaction GO:0007340 13 13 0,000 0,01228718 0,02325253 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01228718 0,02324021 ! nucleolar part GO:0044452 13 13 0,000 0,01228718 0,02322791 ! axoneme part GO:0044447 13 13 0,000 0,01228718 0,02321562 ! tRNA modification GO:0006400 14 14 0,000 0,01322652 0,02497721 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01322652 0,024964 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01322652 0,02495082 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01322652 0,02493764 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01322652 0,02492448 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01322652 0,02491134 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01322652 0,0248982 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01322652 0,02488509 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01322652 0,02487198 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01322652 0,02485889 ! palate development GO:0060021 15 14 0,000 0,01322652 0,02484582 ! centrosome cycle GO:0007098 14 14 0,000 0,01322652 0,02483275 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01322652 0,0248197 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01322652 0,02480667 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01322652 0,02479365 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01322652 0,02478064 ! glycine metabolic process GO:0006544 15 14 0,000 0,01322652 0,02476764 ! plasma membrane organization GO:0007009 14 14 0,000 0,01322652 0,02475466 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01322652 0,02474169 ! response to retinoic acid GO:0032526 14 14 0,000 0,01322652 0,02472874 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01322652 0,0247158 ! lysosomal transport GO:0007041 14 14 0,000 0,01322652 0,02470287 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01322652 0,02468996 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01322652 0,02467706 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01322652 0,02466417 ! bone mineralization GO:0030282 14 14 0,000 0,01322652 0,0246513 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01322652 0,02463844 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 0,000 0,01322652 0,0246256 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01322652 0,02461276 ! cerebellum development GO:0021549 15 14 0,000 0,01322652 0,02459995 ! G1 phase GO:0051318 14 14 0,000 0,01322652 0,02458714 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01322652 0,02457435 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01322652 0,02456157 ! water homeostasis GO:0030104 14 14 0,000 0,01322652 0,0245488 ! peptide hormone binding GO:0017046 14 14 0,000 0,01322652 0,02453605 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01322652 0,02452331 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01322652 0,02451058 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01322652 0,02449787 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01322652 0,02448517 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01322652 0,02447248 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01322652 0,02445981 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01322652 0,02444715 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01322652 0,0244345 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01322652 0,02442187 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01322652 0,02440925 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01322652 0,02439664 ! lactation GO:0007595 15 14 0,000 0,01322652 0,02438404 ! reproductive cellular process GO:0048610 14 14 0,000 0,01322652 0,02437146 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01322652 0,02435889 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01322652 0,02434634 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01322652 0,02433379 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01322652 0,02432126 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01322652 0,02430875 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01322652 0,02429624 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01322652 0,02428375 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01322652 0,02427127 ! startle response GO:0001964 14 14 0,000 0,01322652 0,02425881 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01322652 0,02424635 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01322652 0,02423391 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01322652 0,02422148 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01322652 0,02420907 ! organic alcohol transport GO:0015850 15 14 0,000 0,01322652 0,02419667 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01322652 0,02418428 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01322652 0,0241719 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01322652 0,02415954 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01322652 0,02414719 ! L-amino acid transport GO:0015807 14 14 0,000 0,01322652 0,02413485 ! microfilament motor activity GO:0000146 14 14 0,000 0,01322652 0,02412252 ! stem cell development GO:0048864 14 14 0,000 0,01322652 0,02411021 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01322652 0,02409791 ! DNA replication initiation GO:0006270 14 14 0,000 0,01322652 0,02408562 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01322652 0,02407334 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01322652 0,02406108 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01322652 0,02404883 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01322652 0,02403659 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01322652 0,02402436 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01322652 0,02401215 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01322652 0,02399995 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01322652 0,02398776 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01322652 0,02397558 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01322652 0,02396342 ! ion gated channel activity GO:0022839 16 14 0,000 0,01322652 0,02395127 ! male genitalia development GO:0030539 14 14 0,000 0,01322652 0,02393913 ! regulation of axon extension GO:0030516 15 14 0,000 0,01322652 0,023927 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01322652 0,02391488 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01322652 0,02390278 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01322652 0,02389069 ! defense response to virus GO:0051607 19 14 0,000 0,01322652 0,02387861 ! cadherin binding GO:0045296 16 14 0,000 0,01322652 0,02386655 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01416503 0,02554712 ! nuclear replication fork GO:0043596 16 15 0,000 0,01416503 0,02553423 ! skin development GO:0043588 16 15 0,000 0,01416503 0,02552134 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01416503 0,02550847 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01416503 0,02549562 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01416503 0,02548277 ! polysome GO:0005844 16 15 0,000 0,01416503 0,02546994 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01416503 0,02545712 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01416503 0,02544432 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01416503 0,02543153 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01416503 0,02541875 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01416503 0,02540598 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01416503 0,02539323 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01416503 0,02538048 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01416503 0,02536776 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01416503 0,02535504 ! response to vitamin A GO:0033189 15 15 0,000 0,01416503 0,02534234 ! protease binding GO:0002020 16 15 0,000 0,01416503 0,02532965 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01416503 0,02531697 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01416503 0,0253043 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01416503 0,02529165 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01416503 0,02527901 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01416503 0,02526639 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01416503 0,02525377 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01416503 0,02524117 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01416503 0,02522858 ! filopodium GO:0030175 15 15 0,000 0,01416503 0,025216 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01416503 0,02520344 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01416503 0,02519089 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01416503 0,02517835 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01416503 0,02516582 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01416503 0,02515331 ! SMAD binding GO:0046332 16 15 0,000 0,01416503 0,02514081 ! nerve development GO:0021675 16 15 0,000 0,01416503 0,02512832 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01416503 0,02511584 ! mannose binding GO:0005537 15 15 0,000 0,01416503 0,02510338 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01416503 0,02509092 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01416503 0,02507849 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01416503 0,02506606 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01416503 0,02505364 ! synaptonemal complex GO:0000795 15 15 0,000 0,01416503 0,02504124 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01416503 0,02502885 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01416503 0,02501647 ! water transport GO:0006833 15 15 0,000 0,01416503 0,02500411 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01416503 0,02499175 ! viral genome replication GO:0019079 15 15 0,000 0,01416503 0,02497941 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01416503 0,02496708 ! inositol metabolic process GO:0006020 15 15 0,000 0,01416503 0,02495476 ! sulfate transport GO:0008272 15 15 0,000 0,01416503 0,02494246 ! protein-lipid complex GO:0032994 15 15 0,000 0,01416503 0,02493016 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01416503 0,02491788 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01416503 0,02490562 ! heart looping GO:0001947 15 15 0,000 0,01416503 0,02489336 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01416503 0,02488111 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01416503 0,02486888 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01416503 0,02485666 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01416503 0,02484445 ! response to osmotic stress GO:0006970 16 15 0,000 0,01416503 0,02483226 ! fructose metabolic process GO:0006000 15 15 0,000 0,01416503 0,02482007 ! ubiquitin binding GO:0043130 15 15 0,000 0,01416503 0,0248079 ! vesicle coating GO:0006901 16 15 0,000 0,01416503 0,02479574 ! DNA integration GO:0015074 16 15 0,000 0,01416503 0,02478359 ! alcohol binding GO:0043178 16 15 0,000 0,01416503 0,02477145 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01416503 0,02475933 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01416503 0,02474721 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01416503 0,02473511 ! genitalia development GO:0048806 15 15 0,000 0,01416503 0,02472302 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01416503 0,02471095 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01416503 0,02469888 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01416503 0,02468683 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01416503 0,02467478 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01416503 0,02466275 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01416503 0,02465073 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01416503 0,02463873 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01416503 0,02462673 ! receptor activator activity GO:0030546 15 15 0,000 0,01416503 0,02461475 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01416503 0,02460277 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01416503 0,02459081 ! histone binding GO:0042393 15 15 0,000 0,01416503 0,02457887 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01416503 0,02456693 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01416503 0,024555 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01416503 0,02454309 ! drug transporter activity GO:0015238 15 15 0,000 0,01416503 0,02453119 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01416503 0,02451929 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01416503 0,02450742 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01416503 0,02449555 ! peptide hormone processing GO:0016486 17 15 0,000 0,01416503 0,02448369 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01416503 0,02447185 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01416503 0,02446001 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,0151027 0,02606658 ! positive regulation of cell size GO:0045793 16 16 0,000 0,0151027 0,02605399 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,0151027 0,02604141 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,0151027 0,02602884 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,0151027 0,02601628 ! response to vitamin GO:0033273 16 16 0,000 0,0151027 0,02600374 ! gene silencing by RNA GO:0031047 16 16 0,000 0,0151027 0,02599121 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,0151027 0,02597869 ! kinesin complex GO:0005871 16 16 0,000 0,0151027 0,02596618 ! cornified envelope GO:0001533 18 16 0,000 0,0151027 0,02595368 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,0151027 0,0259412 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,0151027 0,02592873 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,0151027 0,02591627 ! pituitary gland development GO:0021983 16 16 0,000 0,0151027 0,02590382 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,0151027 0,02589138 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,0151027 0,02587896 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,0151027 0,02586655 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,0151027 0,02585415 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,0151027 0,02584176 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,0151027 0,02582938 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,0151027 0,02581702 ! beta-catenin binding GO:0008013 17 16 0,000 0,0151027 0,02580467 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,0151027 0,02579233 ! neuron recognition GO:0008038 17 16 0,000 0,0151027 0,02578 ! oogenesis GO:0048477 19 16 0,000 0,0151027 0,02576768 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,0151027 0,02575537 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,0151027 0,02574308 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,0151027 0,0257308 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,0151027 0,02571853 ! biomineral formation GO:0031214 16 16 0,000 0,0151027 0,02570627 ! vitamin transport GO:0051180 16 16 0,000 0,0151027 0,02569402 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,0151027 0,02568179 ! organic cation transport GO:0015695 16 16 0,000 0,0151027 0,02566956 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,0151027 0,02565735 ! regulation of glucose import GO:0046324 17 16 0,000 0,0151027 0,02564515 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,0151027 0,02563296 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,0151027 0,02562079 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,0151027 0,02560862 ! tRNA binding GO:0000049 16 16 0,000 0,0151027 0,02559647 ! regulation of cell killing GO:0031341 20 16 0,000 0,0151027 0,02558432 ! negative regulation of defense response GO:0031348 16 16 0,000 0,0151027 0,02557219 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,0151027 0,02556007 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,0151027 0,02554797 ! bile acid metabolic process GO:0008206 16 16 0,000 0,0151027 0,02553587 ! axis specification GO:0009798 16 16 0,000 0,0151027 0,02552378 ! adult walking behavior GO:0007628 17 16 0,000 0,0151027 0,02551171 ! C-C chemokine binding GO:0019957 16 16 0,000 0,0151027 0,02549965 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,0151027 0,0254876 ! protein phosphatase binding GO:0019903 17 16 0,000 0,0151027 0,02547556 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,0151027 0,02546353 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,0151027 0,02545151 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0151027 0,02543951 ! SH2 domain binding GO:0042169 19 16 0,000 0,0151027 0,02542751 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,0151027 0,02541553 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,0151027 0,02540356 ! neutral amino acid transport GO:0015804 16 16 0,000 0,0151027 0,0253916 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,0151027 0,02537965 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,0151027 0,02536771 ! cellular pigmentation GO:0033059 16 16 0,000 0,0151027 0,02535578 ! mannosidase activity GO:0015923 19 16 0,000 0,0151027 0,02534387 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,0151027 0,02533197 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,0151027 0,02532007 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,0151027 0,02530819 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,0151027 0,02529632 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,0151027 0,02528446 ! sperm-egg recognition GO:0035036 17 16 0,000 0,0151027 0,02527261 ! axoneme GO:0005930 16 16 0,000 0,0151027 0,02526077 ! neuron maturation GO:0042551 18 17 0,000 0,01603955 0,02681519 ! metencephalon development GO:0022037 18 17 0,000 0,01603955 0,02680264 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01603955 0,02679011 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01603955 0,02677758 ! hemoglobin complex GO:0005833 18 17 0,000 0,01603955 0,02676507 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01603955 0,02675257 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01603955 0,02674008 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01603955 0,0267276 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01603955 0,02671513 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01603955 0,02670268 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01603955 0,02669024 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01603955 0,0266778 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01603955 0,02666538 ! glial cell development GO:0021782 17 17 0,000 0,01603955 0,02665298 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01603955 0,02664058 ! pancreas development GO:0031016 17 17 0,000 0,01603955 0,02662819 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01603955 0,02661582 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01603955 0,02660346 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01603955 0,02659111 ! cerebral cortex development GO:0021987 17 17 0,000 0,01603955 0,02657877 ! cellular response to starvation GO:0009267 18 17 0,000 0,01603955 0,02656644 ! signal sequence binding GO:0005048 17 17 0,000 0,01603955 0,02655412 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01603955 0,02654182 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01603955 0,02652953 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01603955 0,02651724 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01603955 0,02650497 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01603955 0,02649271 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01603955 0,02648047 ! actin filament bundle GO:0032432 17 17 0,000 0,01603955 0,02646823 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01603955 0,026456 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01603955 0,02644379 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01603955 0,02643159 ! regulation of protein binding GO:0043393 18 17 0,000 0,01603955 0,02641939 ! recycling endosome GO:0055037 18 17 0,000 0,01603955 0,02640721 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01603955 0,02639504 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01603955 0,02638289 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01603955 0,02637074 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01603955 0,0263586 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01603955 0,02634648 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01603955 0,02633437 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01603955 0,02632226 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01603955 0,02631017 ! steroid catabolic process GO:0006706 17 17 0,000 0,01603955 0,02629809 ! oxygen transport GO:0015671 18 17 0,000 0,01603955 0,02628602 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01603955 0,02627397 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01603955 0,02626192 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01603955 0,02624988 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01603955 0,02623786 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 0,01603955 0,02622585 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01603955 0,02621384 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01603955 0,02620185 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01603955 0,02618987 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01603955 0,0261779 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01603955 0,02616594 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01603955 0,02615399 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01603955 0,02614206 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01603955 0,02613013 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01603955 0,02611822 ! fucose metabolic process GO:0006004 19 17 0,000 0,01603955 0,02610631 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01603955 0,02609442 ! membrane budding GO:0006900 18 17 0,000 0,01603955 0,02608253 ! AMP binding GO:0016208 17 17 0,000 0,01603955 0,02607066 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01603955 0,0260588 ! body fluid secretion GO:0007589 18 17 0,000 0,01603955 0,02604695 ! response to fungus GO:0009620 17 17 0,000 0,01603955 0,02603511 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01603955 0,02602328 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01603955 0,02601147 ! rRNA binding GO:0019843 17 17 0,000 0,01603955 0,02599966 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01603955 0,02598786 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01603955 0,02597608 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01603955 0,0259643 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01603955 0,02595254 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01603955 0,02594078 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01603955 0,02592904 ! tissue regeneration GO:0042246 17 17 0,000 0,01603955 0,02591731 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01603955 0,02590558 ! muscle maintenance GO:0046716 18 17 0,000 0,01603955 0,02589387 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01603955 0,02588217 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01603955 0,02587048 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01603955 0,0258588 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01603955 0,02584713 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01603955 0,02583547 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01603955 0,02582383 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01697558 0,02731851 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01697558 0,02730621 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01697558 0,02729391 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01697558 0,02728163 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01697558 0,02726936 ! limbic system development GO:0021761 18 18 0,000 0,01697558 0,0272571 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01697558 0,02724485 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01697558 0,02723261 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01697558 0,02722038 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01697558 0,02720816 ! lysosome organization GO:0007040 18 18 0,000 0,01697558 0,02719596 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01697558 0,02718376 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01697558 0,02717158 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01697558 0,0271594 ! peptide cross-linking GO:0018149 20 18 0,000 0,01697558 0,02714724 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01697558 0,02713509 ! presynaptic membrane GO:0042734 19 18 0,000 0,01697558 0,02712295 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01697558 0,02711082 ! neural crest cell migration GO:0001755 18 18 0,000 0,01697558 0,0270987 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01697558 0,02708659 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01697558 0,02707449 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01697558 0,0270624 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01697558 0,02705033 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01697558 0,02703826 ! cell-cell recognition GO:0009988 19 18 0,000 0,01697558 0,02702621 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01697558 0,02701416 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01697558 0,02700213 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01697558 0,02699011 ! actin filament-based movement GO:0030048 18 18 0,000 0,01697558 0,0269781 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01697558 0,0269661 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01697558 0,02695411 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01697558 0,02694213 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01697558 0,02693016 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01697558 0,0269182 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01697558 0,02690625 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01697558 0,02689431 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01697558 0,02688239 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01697558 0,02687047 ! memory GO:0007613 19 18 0,000 0,01697558 0,02685857 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01697558 0,02684667 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01697558 0,02683479 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01697558 0,02682291 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01697558 0,02681105 ! pigmentation during development GO:0048066 21 18 0,000 0,01697558 0,0267992 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01697558 0,02678735 ! acetylcholine binding GO:0042166 19 18 0,000 0,01697558 0,02677552 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01697558 0,0267637 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01697558 0,02675189 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01697558 0,02674009 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01697558 0,0267283 ! coreceptor activity GO:0015026 18 18 0,000 0,01697558 0,02671652 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01697558 0,02670475 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01697558 0,02669299 ! cytolysis GO:0019835 18 18 0,000 0,01697558 0,02668124 ! phosphate binding GO:0042301 19 18 0,000 0,01697558 0,0266695 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01697558 0,02665778 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01697558 0,02664606 ! DNA modification GO:0006304 20 18 0,000 0,01697558 0,02663435 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01697558 0,02662265 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01697558 0,02661097 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01697558 0,02659929 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01697558 0,02658762 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01697558 0,02657597 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01697558 0,02656432 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01697558 0,02655269 ! connexon complex GO:0005922 18 18 0,000 0,01697558 0,02654106 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01697558 0,02652945 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01791077 0,02797873 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01791077 0,02796649 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01791077 0,02795427 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01791077 0,02794206 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01791077 0,02792986 ! spindle microtubule GO:0005876 20 19 0,000 0,01791077 0,02791766 ! ovarian follicle development GO:0001541 19 19 0,000 0,01791077 0,02790548 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01791077 0,02789331 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01791077 0,02788115 ! vacuolar transport GO:0007034 19 19 0,000 0,01791077 0,02786901 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01791077 0,02785687 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01791077 0,02784474 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01791077 0,02783262 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01791077 0,02782052 ! cell projection membrane GO:0031253 20 19 0,000 0,01791077 0,02780842 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01791077 0,02779634 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01791077 0,02778426 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01791077 0,0277722 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01791077 0,02776014 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01791077 0,0277481 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01791077 0,02773607 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01791077 0,02772404 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01791077 0,02771203 ! retinoid binding GO:0005501 19 19 0,000 0,01791077 0,02770003 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01791077 0,02768804 ! protein stabilization GO:0050821 20 19 0,000 0,01791077 0,02767606 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01791077 0,02766409 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01791077 0,02765213 ! microtubule-based transport GO:0010970 19 19 0,000 0,01791077 0,02764018 ! protein complex scaffold GO:0032947 19 19 0,000 0,01791077 0,02762824 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01791077 0,02761631 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01791077 0,02760439 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01791077 0,02759248 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01791077 0,02758058 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01791077 0,02756869 ! glycoprotein binding GO:0001948 23 19 0,000 0,01791077 0,02755682 ! sensory perception of taste GO:0050909 19 19 0,000 0,01791077 0,02754495 ! myoblast differentiation GO:0045445 19 19 0,000 0,01791077 0,02753309 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01791077 0,02752124 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01791077 0,02750941 ! myosin binding GO:0017022 19 19 0,000 0,01791077 0,02749758 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01791077 0,02748576 ! cell aging GO:0007569 19 19 0,000 0,01791077 0,02747396 ! stem cell differentiation GO:0048863 19 19 0,000 0,01791077 0,02746216 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01791077 0,02745037 ! heart process GO:0003015 20 19 0,000 0,01791077 0,0274386 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01791077 0,02742683 ! secretory granule membrane GO:0030667 20 19 0,000 0,01791077 0,02741507 ! MHC protein binding GO:0042287 19 19 0,000 0,01791077 0,02740333 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01791077 0,02739159 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01791077 0,02737987 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01791077 0,02736815 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01791077 0,02735644 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01791077 0,02734475 ! insulin receptor binding GO:0005158 20 19 0,000 0,01791077 0,02733306 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01791077 0,02732139 ! protein secretion GO:0009306 20 20 0,000 0,01884514 0,02873442 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01884514 0,02872215 ! proteasome core complex GO:0005839 20 20 0,000 0,01884514 0,0287099 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01884514 0,02869766 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01884514 0,02868542 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01884514 0,0286732 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,01884514 0,02866099 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01884514 0,02864879 ! actomyosin GO:0042641 20 20 0,000 0,01884514 0,0286366 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01884514 0,02862442 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01884514 0,02861225 ! vacuole organization GO:0007033 20 20 0,000 0,01884514 0,02860009 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01884514 0,02858794 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01884514 0,0285758 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,01884514 0,02856367 ! regulation of exocytosis GO:0017157 21 20 0,000 0,01884514 0,02855155 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01884514 0,02853944 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01884514 0,02852734 ! kinase activator activity GO:0019209 20 20 0,000 0,01884514 0,02851526 ! diencephalon development GO:0021536 20 20 0,000 0,01884514 0,02850318 ! nuclear inner membrane GO:0005637 20 20 0,000 0,01884514 0,02849111 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,01884514 0,02847905 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,01884514 0,02846701 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01884514 0,02845497 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,01884514 0,02844294 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,01884514 0,02843093 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,01884514 0,02841892 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01884514 0,02840692 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01884514 0,02839494 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01884514 0,02838296 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01884514 0,028371 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,01884514 0,02835904 ! alditol metabolic process GO:0019400 21 20 0,000 0,01884514 0,02834709 ! liver development GO:0001889 20 20 0,000 0,01884514 0,02833516 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01884514 0,02832323 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01884514 0,02831132 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01884514 0,02829941 ! response to alkaloid GO:0043279 22 20 0,000 0,01884514 0,02828752 ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01884514 0,02827563 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01884514 0,02826376 ! heme metabolic process GO:0042168 22 20 0,000 0,01884514 0,02825189 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01884514 0,02824003 ! sex determination GO:0007530 20 20 0,000 0,01884514 0,02822819 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01884514 0,02821635 ! peptide secretion GO:0002790 21 20 0,000 0,01884514 0,02820453 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01884514 0,02819271 ! interaction with host GO:0051701 24 20 0,000 0,01884514 0,02818091 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01884514 0,02816911 ! vasodilation GO:0042311 21 20 0,000 0,01884514 0,02815732 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01884514 0,02814555 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01884514 0,02813378 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01884514 0,02812202 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01884514 0,02811028 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01884514 0,02809854 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01884514 0,02808681 ! microvillus GO:0005902 20 20 0,000 0,01884514 0,02807509 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01884514 0,02806339 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01884514 0,02805169 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01977869 0,02942904 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01977869 0,02941678 ! growth cone GO:0030426 22 21 0,000 0,01977869 0,02940453 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01977869 0,0293923 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01977869 0,02938007 ! hormone secretion GO:0046879 22 21 0,000 0,01977869 0,02936785 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01977869 0,02935565 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01977869 0,02934345 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01977869 0,02933127 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,01977869 0,02931909 ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,01977869 0,02930692 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01977869 0,02929477 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01977869 0,02928262 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01977869 0,02927049 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,01977869 0,02925836 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01977869 0,02924625 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01977869 0,02923414 ! Golgi stack GO:0005795 25 21 0,000 0,01977869 0,02922205 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01977869 0,02920996 ! muscle cell development GO:0055001 21 21 0,000 0,01977869 0,02919789 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01977869 0,02918582 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01977869 0,02917377 ! deacetylase activity GO:0019213 22 21 0,000 0,01977869 0,02916172 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01977869 0,02914969 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01977869 0,02913766 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01977869 0,02912564 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01977869 0,02911364 ! pentose metabolic process GO:0019321 22 21 0,000 0,01977869 0,02910164 ! collagen fibril organization GO:0030199 22 21 0,000 0,01977869 0,02908966 ! platelet activation GO:0030168 23 21 0,000 0,01977869 0,02907768 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01977869 0,02906572 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01977869 0,02905376 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01977869 0,02904181 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01977869 0,02902988 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01977869 0,02901795 ! cyclase activity GO:0009975 21 21 0,000 0,01977869 0,02900603 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01977869 0,02899412 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01977869 0,02898223 ! fatty acid binding GO:0005504 21 21 0,000 0,01977869 0,02897034 ! gut development GO:0048565 21 21 0,000 0,01977869 0,02895846 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,01977869 0,02894659 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01977869 0,02893474 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01977869 0,02892289 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01977869 0,02891105 ! positive regulation of fibroblast proliferation GO:0048146 22 21 0,000 0,01977869 0,02889922 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01977869 0,0288874 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01977869 0,02887559 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01977869 0,02886379 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01977869 0,028852 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01977869 0,02884022 ! sterol binding GO:0032934 21 21 0,000 0,01977869 0,02882844 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01977869 0,02881668 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01977869 0,02880493 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01977869 0,02879319 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01977869 0,02878145 ! phosphatase binding GO:0019902 22 21 0,000 0,01977869 0,02876973 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01977869 0,02875802 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01977869 0,02874631 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01977869 0,02873462 ! vesicle targeting GO:0006903 22 21 0,000 0,01977869 0,02872293 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01977869 0,02871126 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01977869 0,02869959 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01977869 0,02868793 ! renal system process GO:0003014 22 21 0,000 0,01977869 0,02867628 ! base-excision repair GO:0006284 21 21 0,000 0,01977869 0,02866465 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01977869 0,02865302 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01977869 0,0286414 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01977869 0,02862979 ! fatty acid transport GO:0015908 21 21 0,000 0,01977869 0,02861819 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01977869 0,0286066 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01977869 0,02859502 ! collagen catabolic process GO:0030574 21 21 0,000 0,01977869 0,02858344 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01977869 0,02857188 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01977869 0,02856033 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01977869 0,02854878 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,02071141 0,029883 ! site of polarized growth GO:0030427 23 22 0,000 0,02071141 0,02987093 ! leukocyte adhesion GO:0007159 27 22 0,000 0,02071141 0,02985887 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,02071141 0,02984682 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,02071141 0,02983478 ! peroxisome organization GO:0007031 22 22 0,000 0,02071141 0,02982275 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,02071141 0,02981073 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,02071141 0,02979872 ! response to starvation GO:0042594 23 22 0,000 0,02071141 0,02978672 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,02071141 0,02977473 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,02071141 0,02976275 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,02071141 0,02975078 ! membrane depolarization GO:0051899 24 22 0,000 0,02071141 0,02973881 ! somitogenesis GO:0001756 23 22 0,000 0,02071141 0,02972686 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,02071141 0,02971492 ! natural killer cell activation GO:0030101 22 22 0,000 0,02071141 0,02970298 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02071141 0,02969106 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,02071141 0,02967914 ! basal plasma membrane GO:0009925 22 22 0,000 0,02071141 0,02966724 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,02071141 0,02965534 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,02071141 0,02964346 ! telomere organization GO:0032200 23 22 0,000 0,02071141 0,02963158 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,02071141 0,02961972 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,02071141 0,02960786 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,02071141 0,02959601 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,02071141 0,02958417 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,02071141 0,02957234 ! initiation of viral infection GO:0019059 22 22 0,000 0,02071141 0,02956052 ! RNA polymerase complex GO:0030880 23 22 0,000 0,02071141 0,02954871 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,02071141 0,02953691 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,02071141 0,02952512 ! response to ethanol GO:0045471 25 22 0,000 0,02071141 0,02951334 ! syntaxin binding GO:0019905 23 22 0,000 0,02071141 0,02950157 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,02071141 0,0294898 ! digestive system process GO:0022600 24 22 0,000 0,02071141 0,02947805 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,02071141 0,02946631 ! autophagy GO:0006914 24 22 0,000 0,02071141 0,02945457 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,02071141 0,02944285 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,02071141 0,02943113 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,02071141 0,02941942 ! transaminase activity GO:0008483 23 22 0,000 0,02071141 0,02940773 ! sarcoplasm GO:0016528 23 22 0,000 0,02071141 0,02939604 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,02071141 0,02938436 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,02071141 0,02937269 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,02071141 0,02936103 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,02071141 0,02934938 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,02071141 0,02933773 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,02071141 0,0293261 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,02071141 0,02931448 ! translational initiation GO:0006413 23 23 0,000 0,0216433 0,03062133 ! NF-kappaB binding GO:0051059 23 23 0,000 0,0216433 0,0306092 ! vesicle docking GO:0048278 23 23 0,000 0,0216433 0,03059708 ! muscle myosin complex GO:0005859 25 23 0,000 0,0216433 0,03058497 ! vasculogenesis GO:0001570 25 23 0,000 0,0216433 0,03057287 ! regulation of innate immune response GO:0045088 23 23 0,000 0,0216433 0,03056079 ! androgen receptor binding GO:0050681 23 23 0,000 0,0216433 0,03054871 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,0216433 0,03053664 ! sperm motility GO:0030317 23 23 0,000 0,0216433 0,03052458 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,0216433 0,03051253 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,0216433 0,03050048 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,0216433 0,03048845 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,0216433 0,03047643 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,0216433 0,03046442 ! regulation of behavior GO:0050795 23 23 0,000 0,0216433 0,03045241 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,0216433 0,03044042 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,0216433 0,03042844 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,0216433 0,03041646 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,0216433 0,03040449 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,0216433 0,03039254 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,0216433 0,03038059 ! pallium development GO:0021543 23 23 0,000 0,0216433 0,03036865 ! GABA receptor activity GO:0016917 24 23 0,000 0,0216433 0,03035673 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,0216433 0,03034481 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,0216433 0,0303329 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,0216433 0,030321 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,0216433 0,03030911 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,0216433 0,03029723 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,0216433 0,03028536 ! cell surface binding GO:0043498 25 23 0,000 0,0216433 0,03027349 ! collagen binding GO:0005518 27 23 0,000 0,0216433 0,03026164 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,0216433 0,03024979 ! regulation of amine transport GO:0051952 23 23 0,000 0,0216433 0,03023796 ! tissue homeostasis GO:0001894 24 23 0,000 0,0216433 0,03022613 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,0216433 0,03021432 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,0216433 0,03020251 ! gluconeogenesis GO:0006094 24 23 0,000 0,0216433 0,03019071 ! iron ion transport GO:0006826 24 23 0,000 0,0216433 0,03017892 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,0216433 0,03016715 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,0216433 0,03015537 ! molting cycle process GO:0022404 23 23 0,000 0,0216433 0,03014361 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,0216433 0,03013186 ! tube lumen formation GO:0035148 26 23 0,000 0,0216433 0,03012012 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,0216433 0,03010839 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,0216433 0,03009666 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,0216433 0,03008495 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,0216433 0,03007324 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,0216433 0,03006154 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,0216433 0,03004985 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,0216433 0,03003818 ! brush border GO:0005903 25 23 0,000 0,0216433 0,03002651 ! caveola GO:0005901 24 23 0,000 0,0216433 0,03001485 ! gap junction GO:0005921 23 23 0,000 0,0216433 0,03000319 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,02257437 0,03128175 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,02257437 0,03126962 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,02257437 0,0312575 ! protein amino acid acylation GO:0043543 26 24 0,000 0,02257437 0,03124538 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,02257437 0,03123327 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,02257437 0,03122118 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02257437 0,03120909 ! MHC class I protein complex GO:0042612 24 24 0,000 0,02257437 0,03119701 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 0,000 0,02257437 0,03118494 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,02257437 0,03117289 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,02257437 0,03116084 ! early endosome membrane GO:0031901 26 24 0,000 0,02257437 0,0311488 ! primary neural tube formation GO:0014020 26 24 0,000 0,02257437 0,03113676 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,02257437 0,03112474 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,02257437 0,03111273 ! immunoglobulin production GO:0002377 28 24 0,000 0,02257437 0,03110073 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,02257437 0,03108873 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,02257437 0,03107675 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,02257437 0,03106477 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,02257437 0,03105281 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,02257437 0,03104085 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,02257437 0,0310289 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,02257437 0,03101696 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,02257437 0,03100503 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,02257437 0,03099311 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,02257437 0,0309812 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,02257437 0,0309693 ! Z disc GO:0030018 27 24 0,000 0,02257437 0,0309574 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,02257437 0,03094552 ! regulation of fibroblast proliferation GO:0048145 25 24 0,000 0,02257437 0,03093365 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,02257437 0,03092178 ! neuron fate commitment GO:0048663 24 24 0,000 0,02257437 0,03090992 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,02257437 0,03089808 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,02257437 0,03088624 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,02257437 0,03087441 ! glucose transport GO:0015758 24 24 0,000 0,02257437 0,03086259 ! dendrite development GO:0016358 26 24 0,000 0,02257437 0,03085078 ! catechol metabolic process GO:0009712 27 24 0,000 0,02257437 0,03083898 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,02257437 0,03082718 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,02257437 0,0308154 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,02257437 0,03080362 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,02257437 0,03079186 ! synaptogenesis GO:0007416 25 24 0,000 0,02257437 0,0307801 ! selenium binding GO:0008430 24 24 0,000 0,02257437 0,03076835 ! leukocyte proliferation GO:0070661 30 24 0,000 0,02257437 0,03075661 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,02257437 0,03074488 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02350462 0,03199962 ! phenol metabolic process GO:0018958 28 25 0,000 0,02350462 0,03198742 ! myelination GO:0042552 26 25 0,000 0,02350462 0,03197524 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02350462 0,03196306 ! hexose transport GO:0008645 25 25 0,000 0,02350462 0,03195089 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02350462 0,03193874 ! PML body GO:0016605 28 25 0,000 0,02350462 0,03192659 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02350462 0,03191445 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02350462 0,03190232 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02350462 0,0318902 ! cell fate determination GO:0001709 25 25 0,000 0,02350462 0,03187809 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02350462 0,03186598 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02350462 0,03185389 ! hormone transport GO:0009914 26 25 0,000 0,02350462 0,03184181 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02350462 0,03182973 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02350462 0,03181767 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02350462 0,03180561 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02350462 0,03179356 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02350462 0,03178152 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02350462 0,03176949 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02350462 0,03175747 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02350462 0,03174546 ! zinc ion transport GO:0006829 26 25 0,000 0,02350462 0,03173346 ! heterochromatin GO:0000792 26 25 0,000 0,02350462 0,03172147 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02350462 0,03170948 ! phototransduction GO:0007602 25 25 0,000 0,02350462 0,03169751 ! keratinization GO:0031424 26 25 0,000 0,02350462 0,03168554 ! spinal cord development GO:0021510 25 25 0,000 0,02350462 0,03167359 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02350462 0,03166164 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02350462 0,0316497 ! response to toxin GO:0009636 25 25 0,000 0,02350462 0,03163777 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02350462 0,03162585 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02350462 0,03161394 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02350462 0,03160203 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02350462 0,03159014 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02350462 0,03157825 ! phospholipid transport GO:0015914 26 25 0,000 0,02350462 0,03156638 ! peptidase activator activity GO:0016504 25 25 0,000 0,02350462 0,03155451 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02350462 0,03154265 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02350462 0,0315308 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,02350462 0,03151896 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02350462 0,03150713 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02350462 0,03149531 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02350462 0,0314835 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02350462 0,03147169 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02350462 0,0314599 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02443405 0,03269164 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02443405 0,03267939 ! regeneration GO:0031099 26 26 0,000 0,02443405 0,03266716 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02443405 0,03265493 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02443405 0,03264272 ! ureteric bud development GO:0001657 26 26 0,000 0,02443405 0,03263051 ! neural crest cell development GO:0014032 26 26 0,000 0,02443405 0,03261831 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02443405 0,03260612 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02443405 0,03259394 ! lipid oxidation GO:0034440 26 26 0,000 0,02443405 0,03258177 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02443405 0,03256961 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02443405 0,03255746 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02443405 0,03254531 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02443405 0,03253318 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02443405 0,03252105 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02443405 0,03250894 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02443405 0,03249683 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02443405 0,03248473 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02443405 0,03247264 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02443405 0,03246056 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02443405 0,03244849 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02443405 0,03243642 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02443405 0,03242437 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02443405 0,03241233 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02443405 0,03240029 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02443405 0,03238826 ! chemokine binding GO:0019956 26 26 0,000 0,02443405 0,03237625 ! receptor metabolic process GO:0043112 28 26 0,000 0,02443405 0,03236424 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02443405 0,03235224 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02443405 0,03234025 ! phospholipase C activity GO:0004629 27 26 0,000 0,02443405 0,03232826 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,02443405 0,03231629 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02443405 0,03230433 ! receptor regulator activity GO:0030545 26 26 0,000 0,02443405 0,03229237 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02443405 0,03228042 ! response to heat GO:0009408 26 26 0,000 0,02443405 0,03226848 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02443405 0,03225656 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02536265 0,03347008 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02536265 0,03345771 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02536265 0,03344536 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02536265 0,03343301 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,02536265 0,03342068 ! iron ion homeostasis GO:0055072 27 27 0,000 0,02536265 0,03340835 ! lipoprotein binding GO:0008034 29 27 0,000 0,02536265 0,03339603 ! deaminase activity GO:0019239 27 27 0,000 0,02536265 0,03338372 ! mesoderm formation GO:0001707 28 27 0,000 0,02536265 0,03337142 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02536265 0,03335913 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02536265 0,03334685 ! neural tube formation GO:0001841 29 27 0,000 0,02536265 0,03333457 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02536265 0,03332231 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02536265 0,03331005 ! integrin complex GO:0008305 28 27 0,000 0,02536265 0,03329781 ! nuclear chromatin GO:0000790 28 27 0,000 0,02536265 0,03328557 ! collagen metabolic process GO:0032963 27 27 0,000 0,02536265 0,03327334 ! post-embryonic development GO:0009791 29 27 0,000 0,02536265 0,03326112 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02536265 0,03324891 ! ovulation cycle process GO:0022602 27 27 0,000 0,02536265 0,03323671 ! SNARE binding GO:0000149 28 27 0,000 0,02536265 0,03322452 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02536265 0,03321233 ! spindle pole GO:0000922 28 27 0,000 0,02536265 0,03320016 ! trans-Golgi network GO:0005802 29 28 0,000 0,02629044 0,03440203 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,02629044 0,03438943 ! cholesterol transport GO:0030301 28 28 0,000 0,02629044 0,03437684 GO:0015918|sterol transport, ! dynein complex GO:0030286 29 28 0,000 0,02629044 0,03436426 ! formation of primary germ layer GO:0001704 29 28 0,000 0,02629044 0,03435168 ! ovulation cycle GO:0042698 28 28 0,000 0,02629044 0,03433912 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,02629044 0,03432656 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,02629044 0,03431402 ! cofactor catabolic process GO:0051187 30 28 0,000 0,02629044 0,03430148 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,02629044 0,03428895 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,02629044 0,03427643 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,02629044 0,03426392 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,02629044 0,03425142 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,02629044 0,03423893 ! membrane docking GO:0022406 28 28 0,000 0,02629044 0,03422645 ! sister chromatid segregation GO:0000819 28 28 0,000 0,02629044 0,03421398 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,02629044 0,03420151 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,02629044 0,03418906 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,02629044 0,03417661 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,02629044 0,03416417 ! caspase regulator activity GO:0043028 28 28 0,000 0,02629044 0,03415175 ! ensheathment of neurons GO:0007272 29 28 0,000 0,02629044 0,03413933 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,02629044 0,03412692 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,02629044 0,03411452 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,02629044 0,03410212 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,02629044 0,03408974 ! glycogen metabolic process GO:0005977 29 28 0,000 0,02629044 0,03407737 ! RNA helicase activity GO:0003724 28 28 0,000 0,02629044 0,034065 ! protein kinase inhibitor activity GO:0004860 28 28 0,000 0,02629044 0,03405265 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,02629044 0,0340403 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,0272174 0,03522774 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,0272174 0,03521498 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,0272174 0,03520222 ! scavenger receptor activity GO:0005044 30 29 0,000 0,0272174 0,03518948 ! spindle organization GO:0007051 30 29 0,000 0,0272174 0,03517674 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,0272174 0,03516402 ! male gonad development GO:0008584 29 29 0,000 0,0272174 0,0351513 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,0272174 0,03513859 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,0272174 0,03512589 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,0272174 0,0351132 ! endocytic vesicle GO:0030139 29 29 0,000 0,0272174 0,03510052 ! Rho GTPase binding GO:0017048 32 29 0,000 0,0272174 0,03508785 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,0272174 0,03507519 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,0272174 0,03506253 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,0272174 0,03504989 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,0272174 0,03503725 ! glucan metabolic process GO:0044042 30 29 0,000 0,0272174 0,03502463 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,0272174 0,03501201 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,0272174 0,0349994 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,0272174 0,0349868 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,0272174 0,03497421 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,0272174 0,03496163 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,0272174 0,03494906 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,0272174 0,0349365 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,0272174 0,03492394 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,0272174 0,0349114 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,0272174 0,03489886 ! detection of visible light GO:0009584 29 29 0,000 0,0272174 0,03488634 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,0272174 0,03487382 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,0272174 0,03486131 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,0272174 0,03484881 ! gene silencing GO:0016458 29 29 0,000 0,0272174 0,03483632 ! hormone binding GO:0042562 30 30 0,000 0,02814355 0,03600881 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,02814355 0,03599592 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,02814355 0,03598303 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,02814355 0,03597015 ! acrosomal vesicle GO:0001669 32 30 0,000 0,02814355 0,03595728 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,02814355 0,03594442 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,02814355 0,03593157 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,02814355 0,03591873 ! glutamate receptor activity GO:0008066 33 30 0,000 0,02814355 0,0359059 ! kinase inhibitor activity GO:0019210 30 30 0,000 0,02814355 0,03589307 ! ceramide metabolic process GO:0006672 30 30 0,000 0,02814355 0,03588026 ! cell fate specification GO:0001708 31 30 0,000 0,02814355 0,03586745 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,02814355 0,03585466 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,02814355 0,03584187 ! PDZ domain binding GO:0030165 32 30 0,000 0,02814355 0,03582909 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,02814355 0,03581632 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,02814355 0,03580356 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,02814355 0,03579081 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,02814355 0,03577807 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,02814355 0,03576534 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,02814355 0,03575261 ! drug binding GO:0008144 30 30 0,000 0,02814355 0,0357399 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,02814355 0,0357272 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,02814355 0,0357145 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02814355 0,03570181 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,02814355 0,03568913 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,02814355 0,03567646 ! aminopeptidase activity GO:0004177 32 30 0,000 0,02814355 0,0356638 ! detection of light stimulus GO:0009583 30 30 0,000 0,02814355 0,03565115 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,02814355 0,03563851 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,02814355 0,03562588 ! meiosis I GO:0007127 31 31 0,000 0,02906887 0,03678417 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,02906887 0,03677114 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,02906887 0,03675812 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,02906887 0,03674511 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,02906887 0,03673211 ! spliceosome assembly GO:0000245 32 31 0,000 0,02906887 0,03671912 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,02906887 0,03670613 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,02906887 0,03669316 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,02906887 0,03668019 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,02906887 0,03666723 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,02906887 0,03665429 ! replication fork GO:0005657 32 31 0,000 0,02906887 0,03664135 ! placenta development GO:0001890 31 31 0,000 0,02906887 0,03662842 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,02906887 0,0366155 ! regulation of pH GO:0006885 31 31 0,000 0,02906887 0,03660259 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,02906887 0,03658969 ! acute-phase response GO:0006953 32 31 0,000 0,02906887 0,03657679 ! peptide transport GO:0015833 32 31 0,000 0,02906887 0,03656391 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,02906887 0,03655103 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,02906887 0,03653817 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,02906887 0,03652531 ! regulation of protein stability GO:0031647 32 31 0,000 0,02906887 0,03651247 ! sarcolemma GO:0042383 33 31 0,000 0,02906887 0,03649963 ! vesicle localization GO:0051648 32 31 0,000 0,02906887 0,0364868 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,02999338 0,037634 ! DNA helicase activity GO:0003678 34 32 0,000 0,02999338 0,03762078 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,02999338 0,03760757 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,02999338 0,03759437 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,02999338 0,03758118 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,02999338 0,037568 ! late endosome membrane GO:0031902 32 32 0,000 0,02999338 0,03755482 ! positive regulation of cell development GO:0010720 33 32 0,000 0,02999338 0,03754166 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,02999338 0,03752851 ! hindbrain development GO:0030902 35 32 0,000 0,02999338 0,03751536 ! aerobic respiration GO:0009060 32 32 0,000 0,02999338 0,03750223 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,02999338 0,0374891 ! regulation of B cell activation GO:0050864 36 32 0,000 0,02999338 0,03747598 ! regulation of muscle development GO:0048634 33 32 0,000 0,02999338 0,03746287 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,02999338 0,03744977 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,02999338 0,03743668 ! response to ionizing radiation GO:0010212 33 32 0,000 0,02999338 0,0374236 ! flagellum GO:0019861 32 32 0,000 0,02999338 0,03741053 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,02999338 0,03739747 ! I band GO:0031674 35 32 0,000 0,02999338 0,03738442 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,02999338 0,03737137 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,02999338 0,03735834 ! adult locomotory behavior GO:0008344 33 32 0,000 0,02999338 0,03734531 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,02999338 0,0373323 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,03091707 0,03846859 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,03091707 0,03845519 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,03091707 0,0384418 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,03091707 0,03842842 ! negative regulation of binding GO:0051100 34 33 0,000 0,03091707 0,03841505 ! organelle envelope lumen GO:0031970 34 33 0,000 0,03091707 0,03840169 ! protein targeting to membrane GO:0006612 35 33 0,000 0,03091707 0,03838834 ! vesicle coat GO:0030120 36 33 0,000 0,03091707 0,03837499 ! endoribonuclease activity GO:0004521 34 33 0,000 0,03091707 0,03836166 ! eye morphogenesis GO:0048592 38 33 0,000 0,03091707 0,03834833 ! embryonic organ development GO:0048568 36 33 0,000 0,03091707 0,03833502 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,03091707 0,03832171 ! glial cell differentiation GO:0010001 33 33 0,000 0,03091707 0,03830842 ! cell junction organization GO:0034330 35 33 0,000 0,03091707 0,03829513 ! tissue remodeling GO:0048771 35 33 0,000 0,03091707 0,03828185 ! segmentation GO:0035282 34 33 0,000 0,03091707 0,03826858 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,03091707 0,03825532 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,03091707 0,03824207 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,03091707 0,03822883 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03091707 0,03821559 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,03091707 0,03820237 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,03091707 0,03818916 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,03091707 0,03817595 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,03091707 0,03816276 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,03183994 0,03928833 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,03183994 0,03927476 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,03183994 0,0392612 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,03183994 0,03924765 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,03183994 0,0392341 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,03183994 0,03922057 ! telencephalon development GO:0021537 34 34 0,000 0,03183994 0,03920705 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,03183994 0,03919353 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,03183994 0,03918003 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,03183994 0,03916653 ! collagen GO:0005581 35 34 0,000 0,03183994 0,03915304 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,03183994 0,03913956 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,03183994 0,0391261 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,03183994 0,03911264 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,03183994 0,03909919 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,03183994 0,03908575 ! spermatid development GO:0007286 34 34 0,000 0,03183994 0,03907231 ! BMP signaling pathway GO:0030509 35 34 0,000 0,03183994 0,03905889 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,03183994 0,03904548 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,032762 0,04016241 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,032762 0,04014863 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,032762 0,04013485 ! vesicle lumen GO:0031983 37 35 0,000 0,032762 0,04012109 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,032762 0,04010734 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,032762 0,04009359 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,032762 0,04007986 ! cytokine production GO:0001816 35 35 0,000 0,032762 0,04006613 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,032762 0,04005241 ! embryonic pattern specification GO:0009880 36 35 0,000 0,032762 0,04003871 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,032762 0,04002501 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,032762 0,04001132 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,032762 0,03999764 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,032762 0,03998397 ! phagocytosis GO:0006909 37 35 0,000 0,032762 0,03997031 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,032762 0,03995666 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,032762 0,03994302 ! ion transmembrane transport GO:0034220 35 35 0,000 0,032762 0,03992939 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,032762 0,03991576 ! oxygen binding GO:0019825 36 35 0,000 0,032762 0,03990215 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,032762 0,03988854 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,032762 0,03987495 ! peripheral nervous system development GO:0007422 37 35 0,000 0,032762 0,03986136 ! female gamete generation GO:0007292 38 35 0,000 0,032762 0,03984779 ! polyol metabolic process GO:0019751 36 35 0,000 0,032762 0,03983422 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,03368324 0,04094039 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,03368324 0,04092646 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,03368324 0,04091254 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,03368324 0,04089862 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,03368324 0,04088472 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,03368324 0,04087083 ! regulation of proteolysis GO:0030162 37 36 0,000 0,03368324 0,04085695 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,03368324 0,04084307 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,03368324 0,04082921 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,03368324 0,04081536 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,03368324 0,04080151 ! spermatid differentiation GO:0048515 36 36 0,000 0,03368324 0,04078768 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,03368324 0,04077385 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,03368324 0,04076003 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,03368324 0,04074622 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,03368324 0,04073243 ! neuropeptide binding GO:0042923 36 36 0,000 0,03368324 0,04071864 ! organic anion transport GO:0015711 37 36 0,000 0,03368324 0,04070486 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,03368324 0,04069109 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,03368324 0,04067733 ! antigen binding GO:0003823 36 36 0,000 0,03368324 0,04066357 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,03368324 0,04064983 ! cytokinesis GO:0000910 40 36 0,000 0,03368324 0,0406361 ! coated pit GO:0005905 42 36 0,000 0,03368324 0,04062238 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,03368324 0,04060866 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,03460367 0,04170425 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,03460367 0,04169018 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,03460367 0,04167612 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,03460367 0,04166207 ! biopolymer methylation GO:0043414 42 37 0,000 0,03460367 0,04164803 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,03460367 0,041634 ! protein homooligomerization GO:0051260 38 37 0,000 0,03460367 0,04161997 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,03460367 0,04160596 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,03460367 0,04159196 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,03460367 0,04157796 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,03460367 0,04156398 ! amino acid binding GO:0016597 40 37 0,000 0,03460367 0,04155 ! maintenance of protein location GO:0045185 38 37 0,000 0,03460367 0,04153603 ! maintenance of location in cell GO:0051651 38 37 0,000 0,03460367 0,04152208 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,03460367 0,04150813 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,03460367 0,04149419 ! ear morphogenesis GO:0042471 39 38 0,000 0,03552328 0,04258262 ! odontogenesis GO:0042476 40 38 0,000 0,03552328 0,04256833 ! organic ether metabolic process GO:0018904 39 38 0,000 0,03552328 0,04255405 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,03552328 0,04253978 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,03552328 0,04252552 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,03552328 0,04251127 ! B cell differentiation GO:0030183 40 38 0,000 0,03552328 0,04249703 ! clathrin coat GO:0030118 43 38 0,000 0,03552328 0,0424828 ! regulation of endocytosis GO:0030100 39 38 0,000 0,03552328 0,04246858 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,03552328 0,04245436 ! cell growth GO:0016049 40 38 0,000 0,03552328 0,04244016 ! positive regulation of defense response GO:0031349 38 38 0,000 0,03552328 0,04242597 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,03552328 0,04241178 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,03552328 0,04239761 ! learning GO:0007612 42 38 0,000 0,03552328 0,04238344 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,03552328 0,04236928 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,03552328 0,04235514 ! endosome transport GO:0016197 40 38 0,000 0,03552328 0,042341 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,03552328 0,04232687 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,03552328 0,04231275 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,03552328 0,04229864 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,03552328 0,04228455 ! pigment metabolic process GO:0042440 42 38 0,000 0,03552328 0,04227046 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,03552328 0,04225637 ! RNA modification GO:0009451 39 38 0,000 0,03552328 0,0422423 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03644208 0,04332046 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03644208 0,04330605 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03644208 0,04329164 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03644208 0,04327724 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03644208 0,04326286 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03644208 0,04324848 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03644208 0,04323411 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03644208 0,04321975 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03644208 0,0432054 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03644208 0,04319106 ! viral infectious cycle GO:0019058 39 39 0,000 0,03644208 0,04317673 ! mammary gland development GO:0030879 41 39 0,000 0,03644208 0,04316241 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03644208 0,0431481 ! amine receptor activity GO:0008227 41 39 0,000 0,03644208 0,0431338 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,03644208 0,04311951 ! monosaccharide binding GO:0048029 39 39 0,000 0,03644208 0,04310522 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03644208 0,04309095 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,03736007 0,0441618 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,03736007 0,04414719 ! peptide metabolic process GO:0006518 41 40 0,000 0,03736007 0,04413258 ! T cell differentiation GO:0030217 45 40 0,000 0,03736007 0,04411799 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03736007 0,0441034 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,03736007 0,04408883 ! neuron migration GO:0001764 42 40 0,000 0,03736007 0,04407426 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03736007 0,04405971 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03736007 0,04404516 ! gliogenesis GO:0042063 40 40 0,000 0,03736007 0,04403063 ! feeding behavior GO:0007631 40 40 0,000 0,03736007 0,0440161 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,03736007 0,04400158 ! nucleus organization GO:0006997 40 40 0,000 0,03736007 0,04398707 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03736007 0,04397258 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03736007 0,04395809 ! chromatin remodeling GO:0006338 43 40 0,000 0,03736007 0,04394361 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,03827724 0,04500758 ! positive regulation of binding GO:0051099 42 41 0,000 0,03827724 0,04499277 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,03827724 0,04497796 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,03827724 0,04496317 ! regulation of translational initiation GO:0006446 41 41 0,000 0,03827724 0,04494838 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,03827724 0,04493361 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,03827724 0,04491884 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,03827724 0,04490408 ! exonuclease activity GO:0004527 42 41 0,000 0,03827724 0,04488934 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,03827724 0,0448746 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,03827724 0,04485987 ! hydro-lyase activity GO:0016836 44 41 0,000 0,03827724 0,04484515 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,03827724 0,04483045 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,03827724 0,04481575 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,03827724 0,04480106 ! metal cluster binding GO:0051540 43 41 0,000 0,03827724 0,04478638 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,03827724 0,04477171 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,03827724 0,04475705 ! double-strand break repair GO:0006302 41 41 0,000 0,03827724 0,0447424 ! RNA catabolic process GO:0006401 44 42 0,000 0,0391936 0,04579855 ! organellar ribosome GO:0000313 43 42 0,000 0,0391936 0,04578357 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,0391936 0,04576859 ! damaged DNA binding GO:0003684 42 42 0,000 0,0391936 0,04575363 ! MHC protein complex GO:0042611 42 42 0,000 0,0391936 0,04573868 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,0391936 0,04572374 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,0391936 0,0457088 ! positive regulation of growth GO:0045927 42 42 0,000 0,0391936 0,04569388 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,0391936 0,04567897 ! chemokine activity GO:0008009 42 42 0,000 0,0391936 0,04566406 ! ruffle GO:0001726 44 42 0,000 0,0391936 0,04564917 ! pigmentation GO:0043473 46 42 0,000 0,0391936 0,04563429 ! developmental growth GO:0048589 42 42 0,000 0,0391936 0,04561941 ! methylation GO:0032259 47 42 0,000 0,0391936 0,04560455 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,0391936 0,04558969 ! regulation of tube size GO:0035150 44 42 0,000 0,0391936 0,04557485 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,0391936 0,04556001 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,0391936 0,04554519 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,0391936 0,04553037 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,04010916 0,0465788 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,04010916 0,04656365 ! induction of apoptosis by intracellular signals GO:0008629 46 43 0,000 0,04010916 0,04654852 ! keratinocyte differentiation GO:0030216 46 43 0,000 0,04010916 0,0465334 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,04010916 0,04651828 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,04010916 0,04650318 ! sulfotransferase activity GO:0008146 44 43 0,000 0,04010916 0,04648809 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,04010916 0,046473 ! channel regulator activity GO:0016247 46 43 0,000 0,04010916 0,04645793 ! histone modification GO:0016570 44 43 0,000 0,04010916 0,04644286 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,04010916 0,04642781 ! synaptosome GO:0019717 47 43 0,000 0,04010916 0,04641277 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,0410239 0,04745589 ! platelet alpha granule GO:0031091 46 44 0,000 0,0410239 0,04744052 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,0410239 0,04742517 ! regulation of ossification GO:0030278 48 44 0,000 0,0410239 0,04740982 ! cell recognition GO:0008037 46 44 0,000 0,0410239 0,04739448 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,0410239 0,04737915 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,0410239 0,04736383 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,0410239 0,04734853 ! cellular component disassembly GO:0022411 45 44 0,000 0,0410239 0,04733323 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,0410239 0,04731794 ! regulation of ion transport GO:0043269 47 44 0,000 0,0410239 0,04730266 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,0410239 0,04728739 ! inner ear development GO:0048839 46 44 0,000 0,0410239 0,04727213 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,0410239 0,04725688 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,0410239 0,04724164 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,0410239 0,04722641 ! chemokine receptor binding GO:0042379 44 44 0,000 0,0410239 0,04721119 ! regulation of mast cell proliferation GO:0070666 48 44 0,000 0,0410239 0,04719599 ! regulation of action potential GO:0001508 50 45 0,000 0,04193783 0,04823188 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,04193783 0,04821635 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,04193783 0,04820083 ! response to temperature stimulus GO:0009266 45 45 0,000 0,04193783 0,04818532 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,04193783 0,04816983 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,04193783 0,04815434 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,04193783 0,04813886 ! excretion GO:0007588 46 45 0,000 0,04193783 0,04812339 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,04193783 0,04810793 ! JNK cascade GO:0007254 45 45 0,000 0,04193783 0,04809248 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,04193783 0,04807704 ! regulation of cell shape GO:0008360 46 45 0,000 0,04193783 0,04806161 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,04193783 0,0480462 ! microbody part GO:0044438 46 45 0,000 0,04193783 0,04803079 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,04285095 0,04906084 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,04285095 0,04904511 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,04285095 0,0490294 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,04285095 0,04901369 ! transport vesicle GO:0030133 49 46 0,000 0,04285095 0,048998 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,04285095 0,04898232 ! synapse organization GO:0050808 51 46 0,000 0,04285095 0,04896664 ! nuclear matrix GO:0016363 49 46 0,000 0,04285095 0,04895098 ! striated muscle contraction GO:0006941 49 46 0,000 0,04285095 0,04893532 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,04285095 0,04891968 ! antioxidant activity GO:0016209 47 46 0,000 0,04285095 0,04890404 ! activation of caspase activity GO:0006919 49 46 0,000 0,04285095 0,04888842 ! aging GO:0007568 48 46 0,000 0,04285095 0,04887281 ! male sex differentiation GO:0046661 46 46 0,000 0,04285095 0,0488572 ! coated vesicle membrane GO:0030662 49 46 0,000 0,04285095 0,04884161 ! covalent chromatin modification GO:0016569 47 46 0,000 0,04285095 0,04882602 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,04285095 0,04881045 ! regulation of leukocyte proliferation GO:0070663 50 46 0,000 0,04285095 0,04879488 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein amino acid lipidation GO:0006497 50 47 0,000 0,04376327 0,04981786 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,04376327 0,04980199 ! carbohydrate transport GO:0008643 47 47 0,000 0,04376327 0,04978612 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,04376327 0,04977026 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,04376327 0,04975442 ! vesicle organization GO:0016050 50 47 0,000 0,04376327 0,04973858 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,04376327 0,04972276 ! cell cortex part GO:0044448 51 47 0,000 0,04376327 0,04970694 ! lipid modification GO:0030258 49 48 0,000 0,04467478 0,05072611 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,04467478 0,05070999 ! epidermal cell differentiation GO:0009913 51 48 0,000 0,04467478 0,05069388 ! mitochondrial transport GO:0006839 49 48 0,000 0,04467478 0,05067777 ! viral reproductive process GO:0022415 52 48 0,000 0,04467478 0,05066168 ! leukocyte migration GO:0050900 49 48 0,000 0,04467478 0,0506456 ! neuromuscular process GO:0050905 49 48 0,000 0,04467478 0,05062952 ! gastrulation GO:0007369 50 48 0,000 0,04467478 0,05061346 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,04467478 0,05059741 ! B cell mediated immunity GO:0019724 51 48 0,000 0,04467478 0,05058137 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,04558548 0,05159611 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,04558548 0,05157977 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,04558548 0,05156343 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,04558548 0,0515471 ! ribonuclease activity GO:0004540 50 49 0,000 0,04558548 0,05153078 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,04558548 0,05151447 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,04558548 0,05149818 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,04558548 0,05148189 ! nucleosome GO:0000786 49 49 0,000 0,04558548 0,05146561 ! kinetochore GO:0000776 50 49 0,000 0,04558548 0,05144935 ! membrane fusion GO:0006944 51 49 0,000 0,04558548 0,05143309 ! endocrine system development GO:0035270 49 49 0,000 0,04558548 0,05141685 ! RNA elongation GO:0006354 51 49 0,000 0,04558548 0,05140061 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,04649537 0,05241003 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,04649537 0,05239349 ! basement membrane GO:0005604 51 50 0,000 0,04649537 0,05237696 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,04649537 0,05236045 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,04649537 0,05234394 ! maintenance of location GO:0051235 51 50 0,000 0,04649537 0,05232744 ! nuclear periphery GO:0034399 53 50 0,000 0,04649537 0,05231096 ! cell redox homeostasis GO:0045454 51 50 0,000 0,04649537 0,05229448 ! integrin binding GO:0005178 53 50 0,000 0,04649537 0,05227801 ! regulation of DNA replication GO:0006275 56 50 0,000 0,04649537 0,05226156 ! amino acid activation GO:0043038 50 50 0,000 0,04649537 0,05224511 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,04649537 0,05222868 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,04740446 0,05323312 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,04740446 0,05321639 ! late endosome GO:0005770 51 51 0,000 0,04740446 0,05319966 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,04740446 0,05318295 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,04740446 0,05316625 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,04740446 0,05314955 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,04740446 0,05313287 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,04740446 0,0531162 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,04740446 0,05309954 ! heart morphogenesis GO:0003007 54 51 0,000 0,04740446 0,05308289 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,04740446 0,05306625 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,04831275 0,05406606 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,04831275 0,05404913 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,04831275 0,0540322 ! DNA damage response, signal transduction GO:0042770 58 52 0,000 0,04831275 0,05401528 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,04831275 0,05399838 ! cell maturation GO:0048469 55 52 0,000 0,04831275 0,05398148 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,04831275 0,0539646 ! regulation of actin filament length GO:0030832 53 52 0,000 0,04831275 0,05394772 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,04831275 0,05393086 ! chloride transport GO:0006821 53 52 0,000 0,04831275 0,053914 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,04831275 0,05389716 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,04831275 0,05388033 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,04831275 0,05386351 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,04831275 0,0538467 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,04831275 0,05382989 ! small ribosomal subunit GO:0015935 52 52 0,000 0,04831275 0,0538131 ! cytokine receptor activity GO:0004896 53 52 0,000 0,04831275 0,05379632 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,04922023 0,05478972 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,04922023 0,05477265 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,04922023 0,05475558 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,04922023 0,05473853 ! synaptic vesicle GO:0008021 57 53 0,000 0,04922023 0,05472149 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,04922023 0,05470446 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,04922023 0,05468744 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,04922023 0,05467043 ! proton transport GO:0015992 53 53 0,000 0,04922023 0,05465343 ! mRNA binding GO:0003729 55 53 0,000 0,04922023 0,05463644 ! single fertilization GO:0007338 55 53 0,000 0,04922023 0,05461946 ! axon GO:0030424 58 54 0,000 0,0501269 0,05560831 ! heat shock protein binding GO:0031072 54 54 0,000 0,0501269 0,05559105 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,0501269 0,05557379 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,0501269 0,05555654 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,0501269 0,0555393 ! tRNA processing GO:0008033 55 54 0,000 0,0501269 0,05552207 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,0501269 0,05550486 ! growth factor receptor binding GO:0070851 56 54 0,000 0,0501269 0,05548765 ! DNA catabolic process GO:0006308 55 54 0,000 0,0501269 0,05547046 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,0501269 0,05545327 ! regulation of cellular component size GO:0032535 56 55 0,000 0,05103278 0,05643792 ! hydrogen transport GO:0006818 55 55 0,000 0,05103278 0,05642045 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,05103278 0,05640298 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,05103278 0,05638553 ! large ribosomal subunit GO:0015934 56 55 0,000 0,05103278 0,05636809 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,05103278 0,05635066 ! positive regulation of secretion GO:0051047 60 56 0,000 0,05193785 0,05733232 ! regulation of mitosis GO:0007088 56 56 0,000 0,05193785 0,0573146 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,05193785 0,0572969 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,05193785 0,0572792 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,05193785 0,05726152 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,05193785 0,05724384 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,05193785 0,05722618 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,05193785 0,05720853 ! mesoderm development GO:0007498 57 56 0,000 0,05193785 0,05719089 ! camera-type eye development GO:0043010 59 56 0,000 0,05193785 0,05717326 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,05284212 0,05815075 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,05284212 0,05813284 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,05284212 0,05811494 ! kidney development GO:0001822 60 57 0,000 0,05284212 0,05809704 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,05284212 0,05807916 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,05284212 0,05806129 ! adult behavior GO:0030534 60 57 0,000 0,05284212 0,05804343 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,05284212 0,05802558 ! myosin complex GO:0016459 59 57 0,000 0,05284212 0,05800775 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,05374558 0,0589814 ! lysosomal membrane GO:0005765 59 58 0,000 0,05374558 0,05896328 ! extracellular matrix organization GO:0030198 59 58 0,000 0,05374558 0,05894517 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,05374558 0,05892707 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,05374558 0,05890899 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,05374558 0,05889091 ! secondary metabolic process GO:0019748 59 58 0,000 0,05374558 0,05887285 ! translation initiation factor activity GO:0003743 58 58 0,000 0,05374558 0,05885479 ! dendrite GO:0030425 61 59 0,000 0,05464825 0,05982493 ! molecular adaptor activity GO:0060090 65 59 0,000 0,05464825 0,05980659 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,05464825 0,05978827 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,05464825 0,05976996 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,05464825 0,05975166 ! regulation of heart contraction GO:0008016 62 59 0,000 0,05464825 0,05973337 ! copper ion binding GO:0005507 61 59 0,000 0,05464825 0,05971509 ! activation of immune response GO:0002253 68 59 0,000 0,05464825 0,05969682 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,05464825 0,05967857 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,05464825 0,05966032 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,05464825 0,05964209 ! cell soma GO:0043025 63 59 0,000 0,05464825 0,05962387 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,05464825 0,05960565 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,05555012 0,06057084 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,05555012 0,06055235 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,05555012 0,06053387 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,05555012 0,0605154 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,05555012 0,06049695 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,05555012 0,0604785 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,05555012 0,06046007 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,05555012 0,06044165 ! chloride channel activity GO:0005254 61 60 0,000 0,05555012 0,06042324 ! negative regulation of protein kinase activity GO:0006469 67 61 0,000 0,05645119 0,06138465 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,05645119 0,06136597 ! fertilization GO:0009566 64 61 0,000 0,05645119 0,06134729 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,05645119 0,06132863 ! gonad development GO:0008406 61 61 0,000 0,05645119 0,06130998 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,05645119 0,06129134 ! regulation of immune effector process GO:0002697 65 61 0,000 0,05645119 0,06127271 ! amine catabolic process GO:0009310 68 62 0,000 0,05735146 0,06223096 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,05735146 0,06221205 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,05735146 0,06219316 ! coated membrane GO:0048475 67 62 0,000 0,05735146 0,06217428 GO:0030117|membrane coat, ! negative regulation of kinase activity GO:0033673 68 62 0,000 0,05735146 0,06215541 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,05735146 0,06213655 ! germ cell development GO:0007281 62 62 0,000 0,05735146 0,06211771 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,05735146 0,06209887 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,05825094 0,06305368 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,05825094 0,06303457 ! protein oligomerization GO:0051259 64 63 0,000 0,05825094 0,06301548 ! transition metal ion transport GO:0000041 65 63 0,000 0,05825094 0,06299639 ! appendage morphogenesis GO:0035107 67 63 0,000 0,05825094 0,06297732 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,05825094 0,06295826 ! cellular defense response GO:0006968 64 63 0,000 0,05825094 0,06293921 ! B cell activation GO:0042113 66 63 0,000 0,05825094 0,06292017 ! antigen processing and presentation GO:0019882 64 63 0,000 0,05825094 0,06290115 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,05825094 0,06288213 ! microtubule motor activity GO:0003777 67 63 0,000 0,05825094 0,06286313 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,05825094 0,06284414 ! organelle localization GO:0051640 66 63 0,000 0,05825094 0,06282516 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,05914961 0,06377514 ! lung development GO:0030324 65 64 0,000 0,05914961 0,06375589 ! respiratory chain GO:0070469 66 64 0,000 0,05914961 0,06373665 ! developmental maturation GO:0021700 67 64 0,000 0,05914961 0,06371743 ! amino acid transport GO:0006865 64 64 0,000 0,05914961 0,06369821 ! anion channel activity GO:0005253 65 64 0,000 0,05914961 0,06367901 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,06004749 0,06462616 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,06004749 0,06460669 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,06004749 0,06458723 ! nuclear pore GO:0005643 69 65 0,000 0,06004749 0,06456778 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,06004749 0,06454834 ! negative regulation of transferase activity GO:0051348 71 65 0,000 0,06004749 0,06452892 ! rhythmic process GO:0048511 66 65 0,000 0,06004749 0,06450951 ! regulation of lipase activity GO:0060191 67 65 0,000 0,06004749 0,06449011 ! adaptive immune response GO:0002250 68 65 0,000 0,06004749 0,06447072 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,06004749 0,06445134 GO:0060173|limb development, ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,06004749 0,06443197 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,06004749 0,06441262 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,06094458 0,06535528 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,06094458 0,06533566 ! urogenital system development GO:0001655 69 66 0,000 0,06094458 0,06531605 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,06094458 0,06529646 ! diacylglycerol binding GO:0019992 71 66 0,000 0,06094458 0,06527687 ! amine binding GO:0043176 70 66 0,000 0,06094458 0,0652573 ! response to nutrient GO:0007584 67 66 0,000 0,06094458 0,06523774 ! acetyltransferase activity GO:0016407 68 66 0,000 0,06094458 0,06521819 ! negative regulation of cell size GO:0045792 70 67 0,000 0,06184087 0,0661575 ! respiratory tube development GO:0030323 68 67 0,000 0,06184087 0,06613769 ! mRNA transport GO:0051028 70 67 0,000 0,06184087 0,06611789 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,06184087 0,0660981 ! tubulin binding GO:0015631 70 67 0,000 0,06184087 0,06607832 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,06184087 0,06605855 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,06184087 0,0660388 ! regulation of caspase activity GO:0043281 70 67 0,000 0,06184087 0,06601906 ! Ras GTPase binding GO:0017016 70 67 0,000 0,06184087 0,06599932 ! humoral immune response GO:0006959 70 67 0,000 0,06184087 0,06597961 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,06184087 0,0659599 ! nucleosome assembly GO:0006334 69 67 0,000 0,06184087 0,0659402 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,06184087 0,06592052 ! muscle cell differentiation GO:0042692 68 68 0,000 0,06273636 0,06685513 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,06273636 0,06683519 ! protein import into nucleus GO:0006606 72 68 0,000 0,06273636 0,06681526 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,06273636 0,06679534 ! protein-DNA complex GO:0032993 69 68 0,000 0,06273636 0,06677543 ! learning or memory GO:0007611 72 68 0,000 0,06273636 0,06675553 ! chloride ion binding GO:0031404 70 68 0,000 0,06273636 0,06673564 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,06273636 0,06671577 ! chromatin assembly GO:0031497 70 68 0,000 0,06273636 0,06669591 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,06273636 0,06667606 ! extrinsic to membrane GO:0019898 68 68 0,000 0,06273636 0,06665622 ! calcium channel activity GO:0005262 73 68 0,000 0,06273636 0,06663639 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,06273636 0,06661658 ! respiratory system development GO:0060541 69 68 0,000 0,06273636 0,06659678 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,06273636 0,06657699 ! regulation of endopeptidase activity GO:0052548 72 69 0,000 0,06363107 0,0675064 ! eye development GO:0001654 74 69 0,000 0,06363107 0,06748635 ! sarcomere GO:0030017 75 69 0,000 0,06363107 0,06746631 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,06363107 0,06744628 ! focal adhesion GO:0005925 75 69 0,000 0,06363107 0,06742627 ! regulation of DNA binding GO:0051101 72 70 0,000 0,06452497 0,06835321 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,06452497 0,06833294 ! early endosome GO:0005769 79 70 0,000 0,06452497 0,06831268 ! response to hypoxia GO:0001666 76 70 0,000 0,06452497 0,06829244 ! nuclear import GO:0051170 74 70 0,000 0,06452497 0,0682722 ! female pregnancy GO:0007565 71 70 0,000 0,06452497 0,06825198 ! rRNA processing GO:0006364 70 70 0,000 0,06452497 0,06823177 ! cytosolic ribosome GO:0022626 70 70 0,000 0,06452497 0,06821157 ! FAD binding GO:0050660 72 71 0,000 0,06541809 0,06913525 ! response to oxygen levels GO:0070482 77 71 0,000 0,06541809 0,06911479 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,06541809 0,06909435 ! defense response to bacterium GO:0042742 71 71 0,000 0,06541809 0,06907392 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,06541809 0,0690535 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,06541809 0,0690331 ! reproductive structure development GO:0048608 71 71 0,000 0,06541809 0,0690127 ! neurotransmitter transport GO:0006836 73 71 0,000 0,06541809 0,06899232 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,06541809 0,06897195 ! phospholipase activity GO:0004620 75 71 0,000 0,06541809 0,06895159 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,06541809 0,06893125 ! cell projection part GO:0044463 75 71 0,000 0,06541809 0,06891091 ! amine biosynthetic process GO:0009309 75 72 0,000 0,06631041 0,06983028 ! meiosis GO:0007126 73 72 0,000 0,06631041 0,0698097 GO:0051327|M phase of meiotic cell cycle, ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,06631041 0,06978912 ! acute inflammatory response GO:0002526 76 72 0,000 0,06631041 0,06976856 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,06631041 0,06974801 ! lipid transporter activity GO:0005319 77 72 0,000 0,06631041 0,06972747 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,06631041 0,06970694 ! negative regulation of transport GO:0051051 74 73 0,000 0,06720195 0,07062335 ! vacuolar membrane GO:0005774 74 73 0,000 0,06720195 0,07060257 ! rRNA metabolic process GO:0016072 73 73 0,000 0,06720195 0,07058181 ! meiotic cell cycle GO:0051321 75 73 0,000 0,06720195 0,07056106 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,06720195 0,07054031 ! regulation of protein transport GO:0051223 77 73 0,000 0,06720195 0,07051959 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,06720195 0,07049887 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,06720195 0,07047816 ! nucleosome organization GO:0034728 76 74 0,000 0,06809269 0,07139137 ! pore complex GO:0046930 78 74 0,000 0,06809269 0,07137041 ! regulation of peptidase activity GO:0052547 78 74 0,000 0,06809269 0,07134947 ! protein localization in nucleus GO:0034504 78 74 0,000 0,06809269 0,07132854 ! myofibril GO:0030016 80 74 0,000 0,06809269 0,07130762 ! regulation of blood pressure GO:0008217 76 74 0,000 0,06809269 0,07128672 ! apical junction complex GO:0043296 74 74 0,000 0,06809269 0,07126582 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,06809269 0,07124494 ! membrane raft GO:0045121 78 74 0,000 0,06809269 0,07122407 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,06809269 0,07120322 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,06809269 0,07118237 ! response to drug GO:0042493 77 75 0,000 0,06898264 0,0720916 ! small GTPase binding GO:0031267 78 75 0,000 0,06898264 0,07207051 ! cell-substrate junction GO:0030055 82 75 0,000 0,06898264 0,07204943 ! positive regulation of cell activation GO:0050867 80 75 0,000 0,06898264 0,07202837 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,06898264 0,07200731 ! phosphoinositide-mediated signaling GO:0048015 79 75 0,000 0,06898264 0,07198627 ! tube morphogenesis GO:0035239 79 75 0,000 0,06898264 0,07196524 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,06898264 0,07194422 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,06898264 0,07192321 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,06898264 0,07190222 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,0698718 0,07280777 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,0698718 0,07278653 ! vitamin metabolic process GO:0006766 77 76 0,000 0,0698718 0,0727653 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,0698718 0,07274409 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,0698718 0,07272288 ! T cell activation GO:0042110 82 76 0,000 0,0698718 0,07270169 ! digestion GO:0007586 80 76 0,000 0,0698718 0,07268052 ! contractile fiber part GO:0044449 82 76 0,000 0,0698718 0,07265935 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,07076018 0,07356175 ! nuclear speck GO:0016607 80 77 0,000 0,07076018 0,07354034 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,07076018 0,07351894 ! endonuclease activity GO:0004519 80 77 0,000 0,07076018 0,07349756 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,07076018 0,07347618 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,07076018 0,07345482 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,07076018 0,07343348 ! vacuolar part GO:0044437 78 77 0,000 0,07076018 0,07341214 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,07164777 0,07431141 ! potassium channel complex GO:0034705 81 78 0,000 0,07164777 0,07428983 GO:0008076|voltage-gated potassium channel complex, ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,07164777 0,07426826 ! blood coagulation GO:0007596 81 78 0,000 0,07164777 0,07424671 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,07253456 0,07514387 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,07253456 0,07512208 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,07253456 0,0751003 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,07253456 0,07507853 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,07253456 0,07505677 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,07253456 0,07503503 ! regulation of T cell activation GO:0050863 84 79 0,000 0,07253456 0,0750133 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,07253456 0,07499158 ! exocytosis GO:0006887 81 79 0,000 0,07253456 0,07496988 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,07253456 0,07494819 ! regulation of protein localization GO:0032880 83 79 0,000 0,07253456 0,07492651 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,07342058 0,0758198 ! GTPase binding GO:0051020 83 80 0,000 0,07342058 0,07579788 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,07342058 0,07577598 ! negative regulation of growth GO:0045926 84 80 0,000 0,07342058 0,07575408 ! regulation of lyase activity GO:0051339 83 80 0,000 0,07342058 0,0757322 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,07342058 0,07571033 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,07342058 0,07568848 ! monooxygenase activity GO:0004497 82 80 0,000 0,07342058 0,07566663 ! condensed chromosome GO:0000793 82 80 0,000 0,07342058 0,0756448 ! contractile fiber GO:0043292 86 80 0,000 0,07342058 0,07562298 ! protein ubiquitination GO:0016567 86 80 0,000 0,07342058 0,07560118 ! ossification GO:0001503 85 81 0,000 0,0743058 0,07649064 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,0743058 0,0764686 ! sterol metabolic process GO:0016125 83 81 0,000 0,0743058 0,07644656 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,0743058 0,07642455 ! protein binding, bridging GO:0030674 86 81 0,000 0,0743058 0,07640254 ! regulation of neurological system process GO:0031644 83 81 0,000 0,0743058 0,07638055 ! protein transporter activity GO:0008565 85 82 0,000 0,07519025 0,07726744 ! positive regulation of immune response GO:0050778 91 82 0,000 0,07519025 0,07724521 ! regulation of defense response GO:0031347 82 82 0,000 0,07519025 0,077223 ! bone development GO:0060348 86 82 0,000 0,07519025 0,0772008 ! carboxylesterase activity GO:0004091 86 82 0,000 0,07519025 0,0771786 ! transcription initiation GO:0006352 86 82 0,000 0,07519025 0,07715643 ! mitochondrion organization GO:0007005 86 83 0,000 0,0760739 0,07804077 ! organelle outer membrane GO:0031968 87 83 0,000 0,0760739 0,07801835 ! hemostasis GO:0007599 86 83 0,000 0,0760739 0,07799595 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,0760739 0,07797357 ! heparin binding GO:0008201 90 83 0,000 0,0760739 0,07795119 ! amine transport GO:0015837 83 83 0,000 0,0760739 0,07792883 ! extracellular matrix part GO:0044420 85 83 0,000 0,0760739 0,07790648 ! phosphoinositide binding GO:0035091 90 83 0,000 0,0760739 0,07788415 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,07695677 0,07876545 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of membrane potential GO:0042391 92 84 0,000 0,07695677 0,07874288 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,07783886 0,07962262 ! cellular respiration GO:0045333 85 85 0,000 0,07783886 0,07959982 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,07783886 0,07957703 ! outer membrane GO:0019867 89 85 0,000 0,07783886 0,07955426 ! DNA recombination GO:0006310 86 85 0,000 0,07783886 0,0795315 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,07783886 0,07950875 ! leukocyte differentiation GO:0002521 95 86 0,000 0,07872017 0,08038597 ! pigment granule GO:0048770 90 86 0,000 0,07872017 0,08036299 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,07872017 0,08034002 ! anion binding GO:0043168 89 86 0,000 0,07872017 0,08031706 ! sex differentiation GO:0007548 86 86 0,000 0,07872017 0,08029412 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,07872017 0,0802712 ! spindle GO:0005819 89 87 0,000 0,07960069 0,0811459 ! microtubule cytoskeleton organization GO:0000226 92 87 0,000 0,07960069 0,08112274 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,07960069 0,08109959 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,07960069 0,08107646 ! protein processing GO:0016485 92 87 0,000 0,07960069 0,08105334 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,08048044 0,08192578 GO:0070035|purine NTP-dependent helicase activity, ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,08048044 0,08190243 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,08048044 0,0818791 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,08048044 0,08185578 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,0813594 0,0827262 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,0813594 0,08270265 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,0813594 0,08267912 ! regulation of binding GO:0051098 93 90 0,000 0,08223758 0,08354777 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,08223758 0,083524 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,08223758 0,08350026 ! external side of plasma membrane GO:0009897 99 90 0,000 0,08223758 0,08347652 ! growth factor binding GO:0019838 92 90 0,000 0,08223758 0,0834528 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,08223758 0,08342909 ! adherens junction GO:0005912 96 90 0,000 0,08223758 0,0834054 ! ATP metabolic process GO:0046034 96 91 0,000 0,08311498 0,08427132 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,08311498 0,0842474 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,08311498 0,0842235 ! forebrain development GO:0030900 95 91 0,000 0,08311498 0,0841996 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,08311498 0,08417572 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,0839916 0,08503942 ! angiogenesis GO:0001525 95 92 0,000 0,0839916 0,08501531 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,0839916 0,08499122 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,0839916 0,08496714 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,0839916 0,08494308 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,0839916 0,08491903 ! gland development GO:0048732 95 92 0,000 0,0839916 0,084895 ! DNA packaging GO:0006323 94 92 0,000 0,0839916 0,08487097 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,08486745 0,08573173 ! receptor complex GO:0043235 97 93 0,000 0,08486745 0,08570748 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,08486745 0,08568325 ! hormone metabolic process GO:0042445 96 93 0,000 0,08486745 0,08565903 ! translational elongation GO:0006414 97 94 0,000 0,08574252 0,08651781 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,08574252 0,08649337 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,08574252 0,08646894 ! protein maturation GO:0051604 99 94 0,000 0,08574252 0,08644453 ! regulation of lymphocyte activation GO:0051249 100 95 0,000 0,08661681 0,08730133 ! carboxylic acid binding GO:0031406 99 95 0,000 0,08661681 0,0872767 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,08661681 0,08725208 ! response to virus GO:0009615 102 95 0,000 0,08661681 0,08722747 ! peroxisome GO:0005777 97 96 0,000 0,08749032 0,0880823 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,08749032 0,08805748 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,08749032 0,08803267 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,08749032 0,08800787 ! cell fate commitment GO:0045165 98 96 0,000 0,08749032 0,08798308 ! response to nutrient levels GO:0031667 98 96 0,000 0,08749032 0,08795831 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,08836306 0,08881072 ! microtubule associated complex GO:0005875 104 97 0,000 0,08836306 0,08878573 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,08836306 0,08876075 ! anchoring junction GO:0070161 103 97 0,000 0,08836306 0,08873579 ! reproductive developmental process GO:0003006 97 97 0,000 0,08836306 0,08871085 ! unfolded protein binding GO:0051082 100 98 0,000 0,08923502 0,08956106 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,08923502 0,0895359 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,08923502 0,08951075 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,08923502 0,08948561 ! chromatin binding GO:0003682 102 99 0,000 0,09010621 0,09033388 ! protein C-terminus binding GO:0008022 106 99 0,000 0,09010621 0,09030852 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,09010621 0,09028318 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,09010621 0,09025786 ! electron transport chain GO:0022900 102 100 0,000 0,09097662 0,09110418 ! tRNA metabolic process GO:0006399 101 100 0,000 0,09097662 0,09107864 ! protein polymerization GO:0051258 114 100 0,000 0,09097662 0,09105312 ! cytokine binding GO:0019955 101 100 0,000 0,09097662 0,0910276 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,09097662 0,09100211 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,09097662 0,09097662