pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5599-7-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 5 5 3,000 5,952E-11 1,369E-07 ! microtubule cytoskeleton organization GO:0000226 120 84 6,000 2,22E-10 2,553E-07 ! natural killer cell mediated immunity GO:0002228 13 9 3,000 1,492E-09 1,144E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! spindle organization GO:0007051 37 30 4,000 2,817E-09 1,62E-06 ! leukocyte mediated cytotoxicity GO:0001909 17 11 3,000 3,896E-09 1,792E-06 ! cell killing GO:0001906 20 14 3,000 1,177E-08 4,512E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 4,51E-08 1,482E-05 ! polyol catabolic process GO:0046174 7 5 2,000 6,703E-08 1,927E-05 GO:0019405|alditol catabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 6,97E-08 1,781E-05 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 6,37E-07 1,465E-04 ! interphase GO:0051325 159 88 4,000 7,146E-07 1,494E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 1,037E-06 1,987E-04 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 1,097E-06 1,941E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 1,394E-06 2,291E-04 ! response to UV GO:0009411 75 46 3,000 1,836E-06 2,815E-04 ! fructose metabolic process GO:0006000 20 16 2,000 3,699E-06 5,318E-04 ! lymphocyte mediated immunity GO:0002449 88 62 3,000 6,14E-06 8,308E-04 ! alditol metabolic process GO:0019400 24 20 2,000 7,491E-06 9,572E-04 ! leukocyte mediated immunity GO:0002443 99 71 3,000 1,056E-05 1,279E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 1,159E-05 1,333E-03 ! sperm motility GO:0030317 27 24 2,000 1,323E-05 1,449E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 2,372E-05 2,48E-03 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 3,208E-05 3,208E-03 ! response to light stimulus GO:0009416 153 96 3,000 3,49E-05 3,344E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 3,658E-05 3,365E-03 ! polyol metabolic process GO:0019751 44 34 2,000 3,859E-05 3,414E-03 ! alcohol biosynthetic process GO:0046165 45 38 2,000 5,412E-05 4,61E-03 ! positive regulation of protein ubiquitination GO:0031398 8 6 1,000 5,48E-05 4,502E-03 ! positive regulation of DNA repair GO:0045739 7 6 1,000 5,48E-05 4,346E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 5,48E-05 4,202E-03 GO:0046530|photoreceptor cell differentiation, ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 5,48E-05 4,066E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,663E-05 5,508E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 7,663E-05 5,341E-03 ! microtubule bundle formation GO:0001578 8 7 1,000 7,663E-05 5,184E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 7,663E-05 5,036E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,02E-04 6,52E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,02E-04 6,344E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 1,02E-04 6,177E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 1,000 1,02E-04 6,018E-03 ! postreplication repair GO:0006301 11 9 1,000 1,31E-04 7,535E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 1,31E-04 7,351E-03 ! establishment of cell polarity GO:0030010 12 9 1,000 1,31E-04 7,176E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,636E-04 8,751E-03 ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 1,636E-04 8,552E-03 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 1,736E-04 8,875E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,83E-04 9,152E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,928E-04 9,433E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,997E-04 9,57E-03 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 1,000 1,997E-04 9,375E-03 ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,997E-04 9,187E-03 ! negative regulation of transferase activity GO:0051348 105 61 2,000 2,239E-04 0,01009944 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 2,239E-04 9,905E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 2,35E-04 0,01019894 ! cartilage condensation GO:0001502 18 12 1,000 2,394E-04 0,01019559 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,394E-04 0,01001022 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 2,704E-04 0,01110387 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 2,704E-04 0,01090906 ! regulation of DNA repair GO:0006282 15 13 1,000 2,826E-04 0,01120467 ! positive regulation of ligase activity GO:0051351 99 69 2,000 3,226E-04 0,01257487 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 3,292E-04 0,01262098 ! negative regulation of caspase activity GO:0043154 20 14 1,000 3,292E-04 0,01241408 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,292E-04 0,01221385 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 3,51E-04 0,01281253 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 3,794E-04 0,01363586 ! positive regulation of cell size GO:0045793 20 15 1,000 3,794E-04 0,01342608 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 3,794E-04 0,01322265 ! skin development GO:0043588 25 15 1,000 3,794E-04 0,0130253 ! centrosome cycle GO:0007098 16 15 1,000 3,794E-04 0,01283375 ! regulation of ligase activity GO:0051340 114 75 2,000 4,124E-04 0,01374775 ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,331E-04 0,01423072 GO:0030968|endoplasmic reticulum unfolded protein response, ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 4,456E-04 0,01443509 ! positive regulation of protein modification process GO:0031401 107 78 2,000 4,628E-04 0,01478436 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,903E-04 0,0154465 ! membrane budding GO:0006900 29 17 1,000 4,903E-04 0,01523777 ! cell-cell junction organization GO:0045216 25 17 1,000 4,903E-04 0,0150346 ! alcohol catabolic process GO:0046164 104 80 2,000 4,985E-04 0,01508628 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 4,985E-04 0,01489035 GO:0010498|proteasomal protein catabolic process, ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 5,509E-04 0,01624357 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 5,509E-04 0,01603795 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 5,509E-04 0,01583748 ! Golgi vesicle transport GO:0048193 138 85 2,000 5,953E-04 0,01690422 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 6,149E-04 0,01724795 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 6,149E-04 0,01704014 ! cell cycle arrest GO:0007050 150 86 2,000 6,16E-04 0,01686729 ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,824E-04 0,01846548 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 7,533E-04 0,02014733 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,533E-04 0,01991575 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 7,533E-04 0,01968943 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 7,533E-04 0,0194682 ! carbohydrate catabolic process GO:0016052 121 93 2,000 7,739E-04 0,01977728 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 8,277E-04 0,02091885 ! microtubule organizing center organization GO:0031023 28 22 1,000 8,277E-04 0,02069148 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 8,277E-04 0,02046899 ! osteoblast differentiation GO:0001649 40 23 1,000 9,054E-04 0,02215291 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 9,054E-04 0,02191972 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 9,054E-04 0,02169139 ! homophilic cell adhesion GO:0007156 149 100 2,000 9,554E-04 0,02265463 ! fat cell differentiation GO:0045444 37 24 1,000 9,865E-04 0,02315219 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,071E-03 0,0248809 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,071E-03 0,02463209 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,159E-03 0,02638839 ! regulation of B cell activation GO:0050864 42 28 1,000 1,344E-03 0,0303169 ! protein targeting to membrane GO:0006612 53 29 1,000 1,442E-03 0,03220721 ! eye morphogenesis GO:0048592 51 29 1,000 1,442E-03 0,03189752 ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,543E-03 0,03380924 ! response to mechanical stimulus GO:0009612 43 31 1,000 1,648E-03 0,03575641 ! meiosis I GO:0007127 52 32 1,000 1,756E-03 0,03773775 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 1,867E-03 0,03975207 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 1,867E-03 0,03938737 ! cell junction organization GO:0034330 63 33 1,000 1,867E-03 0,0390293 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,867E-03 0,03867769 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 1,867E-03 0,03833235 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 1,981E-03 0,0403186 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,981E-03 0,03996493 ! keratinocyte differentiation GO:0030216 47 35 1,000 2,098E-03 0,04196736 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 2,098E-03 0,04160558 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! JNK cascade GO:0007254 54 39 1,000 2,601E-03 0,05112244 ! response to calcium ion GO:0051592 58 40 1,000 2,734E-03 0,0532922 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 2,734E-03 0,05284437 ! double-strand break repair GO:0006302 67 40 1,000 2,734E-03 0,052404 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,734E-03 0,05197091 ! JAK-STAT cascade GO:0007259 53 40 1,000 2,734E-03 0,05154492 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 3,011E-03 0,056298 ! vesicle organization GO:0016050 79 43 1,000 3,154E-03 0,05849692 ! detection of abiotic stimulus GO:0009582 58 44 1,000 3,3E-03 0,06071837 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,3E-03 0,06023648 ! positive regulation of cell cycle GO:0045787 77 45 1,000 3,449E-03 0,06246584 ! response to estrogen stimulus GO:0043627 74 47 1,000 3,757E-03 0,06751049 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,757E-03 0,06698715 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 70 49 1,000 4,077E-03 0,07213801 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 4,242E-03 0,07447961 ! positive regulation of growth GO:0045927 67 50 1,000 4,242E-03 0,07391537 ! skeletal system morphogenesis GO:0048705 78 53 1,000 4,755E-03 0,08222196 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 4,931E-03 0,0846443 ! detection of external stimulus GO:0009581 66 54 1,000 4,931E-03 0,08401731 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 5,294E-03 0,08953446 ! chromosome segregation GO:0007059 83 57 1,000 5,48E-03 0,09200122 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 5,669E-03 0,09448175 ! actin filament organization GO:0007015 95 59 1,000 5,861E-03 0,09697557 ! regulation of cellular response to stress GO:0080135 85 61 1,000 6,253E-03 0,10272976 ! meiosis GO:0007126 96 61 1,000 6,253E-03 0,10200118 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 6,253E-03 0,10128286 ! negative regulation of cell growth GO:0030308 106 62 1,000 6,454E-03 0,10380108 ! meiotic cell cycle GO:0051321 97 62 1,000 6,454E-03 0,10308024 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 6,657E-03 0,10559754 ! cell cycle checkpoint GO:0000075 108 64 1,000 6,864E-03 0,10812609 ! negative regulation of cell size GO:0045792 108 64 1,000 6,864E-03 0,10739054 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 6,864E-03 0,10666493 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 6,864E-03 0,10594906 ! regulation of caspase activity GO:0043281 97 65 1,000 7,073E-03 0,10845217 ! cell-substrate adhesion GO:0031589 121 66 1,000 7,285E-03 0,11096599 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 7,5E-03 0,11349014 ! response to metal ion GO:0010038 103 70 1,000 8,162E-03 0,12270419 ! eye development GO:0001654 111 70 1,000 8,162E-03 0,12190741 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 8,162E-03 0,12112091 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 8,389E-03 0,12368276 ! steroid biosynthetic process GO:0006694 94 71 1,000 8,389E-03 0,12289497 ! regulation of peptidase activity GO:0052547 106 72 1,000 8,618E-03 0,12545411 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 8,618E-03 0,12466509 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 8,618E-03 0,12388593 ! mitochondrion organization GO:0007005 104 73 1,000 8,85E-03 0,12643125 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 8,85E-03 0,12565081 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 9,085E-03 0,12819343 ! response to inorganic substance GO:0010035 115 75 1,000 9,323E-03 0,13074403 ! negative regulation of growth GO:0045926 123 75 1,000 9,323E-03 0,12995164 ! response to unfolded protein GO:0006986 99 76 1,000 9,563E-03 0,13249927 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,688E-03 0,1334226 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,688E-03 0,13262841 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,688E-03 0,13184363 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,688E-03 0,13106808 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,688E-03 0,1303016 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,688E-03 0,12954403 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,688E-03 0,12879522 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,688E-03 0,12805502 ! sleep GO:0030431 11 5 0,000 9,688E-03 0,12732328 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,688E-03 0,12659985 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,688E-03 0,1258846 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,688E-03 0,12517738 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,688E-03 0,12447806 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,688E-03 0,12378652 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,688E-03 0,12310262 ! tongue development GO:0043586 6 5 0,000 9,688E-03 0,12242623 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,688E-03 0,12175723 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,688E-03 0,12109551 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,688E-03 0,12044094 ! cobalt ion transport GO:0006824 9 5 0,000 9,688E-03 0,11979341 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,688E-03 0,1191528 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,688E-03 0,11851901 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,688E-03 0,11789192 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,688E-03 0,11727144 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,688E-03 0,11665745 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,688E-03 0,11604986 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,688E-03 0,11544857 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,688E-03 0,11485347 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,688E-03 0,11426448 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,688E-03 0,1136815 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,688E-03 0,11310443 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,688E-03 0,1125332 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,688E-03 0,11196771 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,688E-03 0,11140787 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,688E-03 0,1108536 ! malate metabolic process GO:0006108 7 5 0,000 9,688E-03 0,11030482 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,688E-03 0,10976145 ! behavioral response to pain GO:0048266 7 5 0,000 9,688E-03 0,1092234 ! clathrin coat assembly GO:0048268 11 5 0,000 9,688E-03 0,1086906 ! phototransduction, visible light GO:0007603 6 5 0,000 9,688E-03 0,10816298 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,688E-03 0,10764045 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,688E-03 0,10712295 ! mating behavior GO:0007617 6 5 0,000 9,688E-03 0,1066104 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,688E-03 0,10610273 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,688E-03 0,10559987 ! rhythmic behavior GO:0007622 12 5 0,000 9,688E-03 0,10510176 ! copulation GO:0007620 7 5 0,000 9,688E-03 0,10460833 ! glial cell fate commitment GO:0021781 12 5 0,000 9,688E-03 0,1041195 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,688E-03 0,10363523 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,688E-03 0,10315543 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,688E-03 0,10268006 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,688E-03 0,10220905 ! apoptotic cell clearance GO:0043277 13 5 0,000 9,688E-03 0,10174234 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,688E-03 0,10127988 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,688E-03 0,1008216 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,688E-03 0,10036745 ! response to protozoan GO:0001562 9 5 0,000 9,688E-03 0,09991737 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,688E-03 0,09947131 ! lymph vessel development GO:0001945 7 5 0,000 9,688E-03 0,09902922 ! endochondral ossification GO:0001958 12 5 0,000 9,688E-03 0,09859103 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,688E-03 0,09815671 ! parathyroid gland development GO:0060017 8 5 0,000 9,688E-03 0,0977262 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,688E-03 0,09729945 ! anagen GO:0042640 6 5 0,000 9,688E-03 0,09687641 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,688E-03 0,09645703 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,688E-03 0,09604127 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,688E-03 0,09562907 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,688E-03 0,0952204 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,688E-03 0,09481521 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,688E-03 0,09441345 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 9,688E-03 0,09401508 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,688E-03 0,09362006 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,688E-03 0,09322834 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,688E-03 0,09283989 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,688E-03 0,09245466 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,688E-03 0,09207262 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,688E-03 0,09169372 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,688E-03 0,09131792 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,688E-03 0,0909452 ! ovulation GO:0030728 6 5 0,000 9,688E-03 0,0905755 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,688E-03 0,0902088 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,688E-03 0,08984505 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,688E-03 0,08948423 ! response to pH GO:0009268 9 5 0,000 9,688E-03 0,08912629 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 9,688E-03 0,08877121 ! proline biosynthetic process GO:0006561 6 5 0,000 9,688E-03 0,08841894 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,688E-03 0,08806946 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,688E-03 0,08772273 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,688E-03 0,08737872 ! polyol biosynthetic process GO:0046173 5 5 0,000 9,688E-03 0,0870374 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,688E-03 0,08669873 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,688E-03 0,08636269 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,688E-03 0,08602924 ! nerve growth factor processing GO:0032455 7 5 0,000 9,688E-03 0,08569836 ! urea metabolic process GO:0019627 6 5 0,000 9,688E-03 0,08537001 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,688E-03 0,08504417 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,688E-03 0,08472081 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,688E-03 0,0843999 ! neutrophil activation GO:0042119 5 5 0,000 9,688E-03 0,08408141 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,688E-03 0,08376531 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,688E-03 0,08345159 ! response to food GO:0032094 5 5 0,000 9,688E-03 0,0831402 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,688E-03 0,08283113 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,688E-03 0,08252435 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,688E-03 0,08221983 ! forebrain neuron development GO:0021884 7 5 0,000 9,688E-03 0,08191755 ! melanosome organization GO:0032438 7 5 0,000 9,688E-03 0,08161749 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,688E-03 0,08131961 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,688E-03 0,0810239 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,688E-03 0,08073034 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,688E-03 0,08043889 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,688E-03 0,08014955 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,688E-03 0,07986227 ! nucleoside transport GO:0015858 6 5 0,000 9,688E-03 0,07957705 ! nucleoside salvage GO:0043174 7 5 0,000 9,688E-03 0,07929386 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,688E-03 0,07901267 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,688E-03 0,07873348 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,688E-03 0,07845624 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,688E-03 0,07818096 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,688E-03 0,0779076 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,688E-03 0,07763614 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,688E-03 0,07736657 ! depyrimidination GO:0045008 8 5 0,000 9,688E-03 0,07709887 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,688E-03 0,07683301 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,688E-03 0,07656898 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,688E-03 0,07630676 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,688E-03 0,07604633 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,688E-03 0,07578767 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,688E-03 0,07553076 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,688E-03 0,07527559 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,688E-03 0,07502213 ! monocyte differentiation GO:0030224 8 5 0,000 9,688E-03 0,07477038 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,688E-03 0,07452031 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,688E-03 0,07427191 ! centrosome duplication GO:0051298 5 5 0,000 9,688E-03 0,07402516 ! response to UV-C GO:0010225 6 5 0,000 9,688E-03 0,07378004 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,688E-03 0,07353655 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,688E-03 0,07329465 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,688E-03 0,07305434 ! regulation of dendrite development GO:0050773 12 5 0,000 9,688E-03 0,0728156 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,688E-03 0,07257842 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,688E-03 0,07234277 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,688E-03 0,07210865 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,688E-03 0,07187604 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,688E-03 0,07164493 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,688E-03 0,0714153 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,688E-03 0,07118714 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,688E-03 0,07096043 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,688E-03 0,07073515 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,688E-03 0,07051131 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,688E-03 0,07028888 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,688E-03 0,07006784 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,688E-03 0,06984819 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,688E-03 0,06962992 ! neural tube patterning GO:0021532 6 5 0,000 9,688E-03 0,069413 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,688E-03 0,06919743 ! histone demethylation GO:0016577 9 5 0,000 9,688E-03 0,0689832 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,688E-03 0,06877029 ! regulation of sterol transport GO:0032371 7 5 0,000 9,688E-03 0,06855869 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,688E-03 0,06834839 ! enteric nervous system development GO:0048484 8 5 0,000 9,688E-03 0,06813937 ! establishment of planar polarity GO:0001736 6 5 0,000 9,688E-03 0,06793163 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,688E-03 0,06772515 ! muscle cell proliferation GO:0033002 8 5 0,000 9,688E-03 0,06751992 ! transcription termination GO:0006353 8 5 0,000 9,688E-03 0,06731593 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,688E-03 0,06711317 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,688E-03 0,06691163 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,688E-03 0,0667113 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,688E-03 0,06651216 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 9,688E-03 0,06631421 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,688E-03 0,06611743 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,688E-03 0,06592182 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,688E-03 0,06572736 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,688E-03 0,06553404 ! apical protein localization GO:0045176 6 5 0,000 9,688E-03 0,06534186 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 9,688E-03 0,0651508 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,688E-03 0,06496086 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,688E-03 0,06477202 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,688E-03 0,06458427 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,688E-03 0,06439761 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,688E-03 0,06421203 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,688E-03 0,06402751 ! glial cell migration GO:0008347 10 5 0,000 9,688E-03 0,06384405 ! determination of adult lifespan GO:0008340 8 5 0,000 9,688E-03 0,06366164 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,688E-03 0,06348027 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,688E-03 0,06329992 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,688E-03 0,0631206 ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,688E-03 0,0629423 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,688E-03 0,062765 ! neural plate development GO:0001840 6 5 0,000 9,688E-03 0,06258869 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 9,688E-03 0,06241337 ! regulation of sensory perception GO:0051931 6 5 0,000 9,688E-03 0,06223903 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,688E-03 0,06206566 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,688E-03 0,06189326 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 9,688E-03 0,06172181 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,688E-03 0,06155131 ! sensory cilium assembly GO:0035058 6 5 0,000 9,688E-03 0,06138175 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,688E-03 0,06121311 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,688E-03 0,06104541 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,688E-03 0,06087862 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,688E-03 0,06071273 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,688E-03 0,06054775 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,688E-03 0,06038367 ! organ regeneration GO:0031100 7 5 0,000 9,688E-03 0,06022047 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,688E-03 0,06005815 ! carnitine metabolic process GO:0009437 5 5 0,000 9,688E-03 0,0598967 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 9,688E-03 0,05973612 ! cellular anion homeostasis GO:0030002 6 5 0,000 9,688E-03 0,0595764 GO:0055081|anion homeostasis, ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 9,806E-03 0,06014421 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,010052 0,06148828 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,01030061 0,06284191 ! regulation of lyase activity GO:0051339 133 79 1,000 0,01030061 0,06267567 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,010806 0,06557728 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,010806 0,06540471 ! response to protein stimulus GO:0051789 111 81 1,000 0,010806 0,06523304 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,010806 0,06506227 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01106275 0,06643425 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,01106275 0,06626125 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,01132219 0,06763906 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! tRNA transcription GO:0009304 11 6 0,000 0,01161421 0,06920383 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01161421 0,06902501 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01161421 0,06884711 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01161421 0,06867013 GO:0030816|positive regulation of cAMP metabolic process, ! regulation of helicase activity GO:0051095 11 6 0,000 0,01161421 0,06849405 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01161421 0,06831887 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01161421 0,06814459 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01161421 0,06797119 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01161421 0,06779868 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01161421 0,06762703 ! prostate gland development GO:0030850 9 6 0,000 0,01161421 0,06745626 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01161421 0,06728634 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01161421 0,06711728 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01161421 0,06694907 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01161421 0,0667817 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01161421 0,06661516 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01161421 0,06644945 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01161421 0,06628456 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01161421 0,06612049 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01161421 0,06595723 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01161421 0,06579478 ! neuron adhesion GO:0007158 9 6 0,000 0,01161421 0,06563312 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01161421 0,06547225 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01161421 0,06531217 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01161421 0,06515288 ! signal peptide processing GO:0006465 8 6 0,000 0,01161421 0,06499435 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01161421 0,0648366 ! mRNA stabilization GO:0048255 15 6 0,000 0,01161421 0,06467961 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01161421 0,06452338 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01161421 0,0643679 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01161421 0,06421317 ! opsonization GO:0008228 8 6 0,000 0,01161421 0,06405918 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01161421 0,06390593 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01161421 0,06375341 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01161421 0,06360162 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01161421 0,06345054 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01161421 0,06330019 ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01161421 0,06315054 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01161421 0,0630016 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01161421 0,06285336 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01161421 0,06270582 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01161421 0,06255897 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01161421 0,0624128 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01161421 0,06226732 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01161421 0,06212251 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01161421 0,06197837 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01161421 0,0618349 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01161421 0,0616921 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01161421 0,06154995 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01161421 0,06140846 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01161421 0,06126761 ! thymic T cell selection GO:0045061 12 6 0,000 0,01161421 0,06112741 ! protein lipoylation GO:0009249 10 6 0,000 0,01161421 0,06098785 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01161421 0,06084893 ! pigment granule organization GO:0048753 11 6 0,000 0,01161421 0,06071063 ! drug transport GO:0015893 6 6 0,000 0,01161421 0,06057297 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01161421 0,06043592 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01161421 0,0602995 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01161421 0,06016369 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01161421 0,06002849 ! histidine metabolic process GO:0006547 6 6 0,000 0,01161421 0,0598939 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01161421 0,05975991 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01161421 0,05962652 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01161421 0,05949372 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01161421 0,05936151 ! adenohypophysis development GO:0021984 10 6 0,000 0,01161421 0,05922989 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01161421 0,05909885 ! hyperosmotic response GO:0006972 8 6 0,000 0,01161421 0,05896839 ! microtubule nucleation GO:0007020 10 6 0,000 0,01161421 0,0588385 ! ER overload response GO:0006983 7 6 0,000 0,01161421 0,05870918 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01161421 0,05858044 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01161421 0,05845225 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01161421 0,05832463 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01161421 0,05819756 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01161421 0,05807104 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01161421 0,05794507 ! response to dietary excess GO:0002021 7 6 0,000 0,01161421 0,05781965 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01161421 0,05769477 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01161421 0,05757043 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01161421 0,05744662 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01161421 0,05732335 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01161421 0,0572006 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01161421 0,05707837 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01161421 0,05695667 ! neuron apoptosis GO:0051402 8 6 0,000 0,01161421 0,05683549 ! organic alcohol transport GO:0015850 9 6 0,000 0,01161421 0,05671482 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01161421 0,05659466 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01161421 0,05647501 ! male sex determination GO:0030238 9 6 0,000 0,01161421 0,05635586 ! carnitine transport GO:0015879 8 6 0,000 0,01161421 0,05623722 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01161421 0,05611907 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01161421 0,05600142 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01161421 0,05588427 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01161421 0,0557676 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01161421 0,05565141 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01161421 0,05553571 ! parturition GO:0007567 12 6 0,000 0,01161421 0,0554205 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01161421 0,05530575 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01161421 0,05519149 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01161421 0,05507769 ! spindle checkpoint GO:0031577 14 6 0,000 0,01161421 0,05496436 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01161421 0,0548515 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01161421 0,0547391 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01161421 0,05462716 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01161421 0,05451567 ! macrophage differentiation GO:0030225 10 6 0,000 0,01161421 0,05440464 ! astrocyte development GO:0014002 14 6 0,000 0,01161421 0,05429406 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01161421 0,05418393 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01161421 0,05407425 ! interaction with symbiont GO:0051702 8 6 0,000 0,01161421 0,05396501 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01161421 0,05385621 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01161421 0,05374784 ! eating behavior GO:0042755 6 6 0,000 0,01161421 0,05363992 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01161421 0,05353242 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01161421 0,05342536 ! response to copper ion GO:0046688 9 6 0,000 0,01161421 0,05331872 ! DNA topological change GO:0006265 8 6 0,000 0,01161421 0,05321251 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01161421 0,05310672 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01161421 0,05300135 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01161421 0,05289639 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01161421 0,05279186 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01161421 0,05268773 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01161421 0,05258401 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01161421 0,0524807 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01161421 0,0523778 ! gas homeostasis GO:0033483 11 6 0,000 0,01161421 0,0522753 ! hair follicle maturation GO:0048820 7 6 0,000 0,01161421 0,0521732 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01161421 0,0520715 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01161421 0,05197019 ! Schwann cell development GO:0014044 14 6 0,000 0,01161421 0,05186928 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01161421 0,05176876 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01161421 0,05166862 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01161421 0,05156888 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01161421 0,05146952 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01161421 0,05137054 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01161421 0,05127194 ! histone ubiquitination GO:0016574 7 6 0,000 0,01161421 0,05117371 ! regulation of meiosis GO:0040020 10 6 0,000 0,01161421 0,05107587 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01161421 0,05097839 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01161421 0,05088129 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01161421 0,05078456 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01161421 0,0506882 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01161421 0,05059219 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01161421 0,05049656 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01161421 0,05040128 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01161421 0,05030636 ! receptor internalization GO:0031623 9 6 0,000 0,01161421 0,0502118 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01161421 0,0501176 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01161421 0,05002374 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01161421 0,04993024 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01161421 0,04983709 ! protein deubiquitination GO:0016579 8 6 0,000 0,01161421 0,04974428 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01161421 0,04965182 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01161421 0,0495597 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01161421 0,04946792 ! axonal fasciculation GO:0007413 9 6 0,000 0,01161421 0,04937649 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01161421 0,04928539 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01161421 0,04919462 ! midbrain development GO:0030901 6 6 0,000 0,01161421 0,04910419 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01161421 0,04901409 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01161421 0,04892432 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01161421 0,04883488 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01161421 0,04874576 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01161421 0,04865697 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01161421 0,04856851 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01161421 0,04848036 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01161421 0,04839253 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01161421 0,04830502 ! adult feeding behavior GO:0008343 6 6 0,000 0,01161421 0,04821783 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01161421 0,04813095 ! blastocyst growth GO:0001832 15 6 0,000 0,01161421 0,04804439 ! pigment granule transport GO:0051904 12 6 0,000 0,01161421 0,04795813 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01161421 0,04787218 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01161421 0,04778655 ! catecholamine transport GO:0051937 7 6 0,000 0,01161421 0,04770121 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01161421 0,04761618 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01161421 0,04753146 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01161421 0,04744703 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01161421 0,04736291 ! protein prenylation GO:0018342 10 6 0,000 0,01161421 0,04727908 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01161421 0,04719555 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01161421 0,04711231 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01161421 0,04702936 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01161421 0,04694671 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01161421 0,04686435 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,01184911 0,04772847 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,01211657 0,04872046 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,01238667 0,04971961 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,01293478 0,05182925 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01353714 0,05414855 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01353714 0,05405454 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01353714 0,05396086 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01353714 0,0538675 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01353714 0,05377447 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01353714 0,05368175 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01353714 0,05358936 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01353714 0,05349728 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01353714 0,05340552 ! reproductive behavior GO:0019098 12 7 0,000 0,01353714 0,05331407 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01353714 0,05322293 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01353714 0,05313211 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01353714 0,0530416 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01353714 0,05295139 ! oligopeptide transport GO:0006857 11 7 0,000 0,01353714 0,05286149 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01353714 0,05277189 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01353714 0,0526826 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01353714 0,05259361 ! RNA methylation GO:0001510 11 7 0,000 0,01353714 0,05250492 ! pericardium development GO:0060039 8 7 0,000 0,01353714 0,05241653 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01353714 0,05232843 ! fibril organization GO:0043206 13 7 0,000 0,01353714 0,05224063 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01353714 0,05215313 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01353714 0,05206591 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01353714 0,05197899 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01353714 0,05189236 ! lipoprotein transport GO:0042953 9 7 0,000 0,01353714 0,05180602 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01353714 0,05171996 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01353714 0,05163419 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01353714 0,0515487 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01353714 0,0514635 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01353714 0,05137858 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01353714 0,05129393 ! chemosensory behavior GO:0007635 9 7 0,000 0,01353714 0,05120957 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01353714 0,05112548 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01353714 0,05104167 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01353714 0,05095813 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01353714 0,05087486 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01353714 0,05079187 ! reflex GO:0060004 12 7 0,000 0,01353714 0,05070915 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01353714 0,05062669 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01353714 0,05054451 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01353714 0,05046259 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01353714 0,05038093 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01353714 0,05029954 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01353714 0,05021841 ! spinal cord patterning GO:0021511 7 7 0,000 0,01353714 0,05013755 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01353714 0,05005694 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01353714 0,04997659 ! adrenal gland development GO:0030325 17 7 0,000 0,01353714 0,0498965 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01353714 0,04981667 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01353714 0,04973709 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01353714 0,04965776 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01353714 0,04957869 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01353714 0,04949987 ! endosome organization GO:0007032 10 7 0,000 0,01353714 0,0494213 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01353714 0,04934297 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01353714 0,0492649 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01353714 0,04918707 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01353714 0,04910949 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01353714 0,04903215 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01353714 0,04895506 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01353714 0,04887821 ! galactose metabolic process GO:0006012 10 7 0,000 0,01353714 0,04880159 ! vesicle fusion GO:0006906 15 7 0,000 0,01353714 0,04872522 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01353714 0,04864909 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01353714 0,04857319 ! organ growth GO:0035265 11 7 0,000 0,01353714 0,04849753 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01353714 0,04842211 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01353714 0,04834692 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01353714 0,04827196 ! retinol metabolic process GO:0042572 9 7 0,000 0,01353714 0,04819724 ! behavioral fear response GO:0001662 13 7 0,000 0,01353714 0,04812275 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01353714 0,04804848 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01353714 0,04797445 ! rRNA modification GO:0000154 12 7 0,000 0,01353714 0,04790064 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01353714 0,04782706 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01353714 0,04775371 ! response to UV-B GO:0010224 11 7 0,000 0,01353714 0,04768058 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01353714 0,04760767 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01353714 0,04753499 ! intermediate filament organization GO:0045109 11 7 0,000 0,01353714 0,04746253 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01353714 0,04739028 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01353714 0,04731826 ! fibrinolysis GO:0042730 9 7 0,000 0,01353714 0,04724646 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01353714 0,04717487 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01353714 0,0471035 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01353714 0,04703235 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01353714 0,04696141 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01353714 0,04689069 ! response to tropane GO:0014073 13 7 0,000 0,01353714 0,04682018 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01353714 0,04674988 ! melanosome localization GO:0032400 10 7 0,000 0,01353714 0,04667979 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01353714 0,04660991 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01353714 0,04654023 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01353714 0,04647077 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01353714 0,04640152 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01353714 0,04633247 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01353714 0,04626362 ! mast cell activation GO:0045576 9 7 0,000 0,01353714 0,04619498 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01353714 0,04612654 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01353714 0,04605831 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01353714 0,04599028 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01353714 0,04592244 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01353714 0,04585481 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01353714 0,04578738 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01353714 0,04572014 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01353714 0,0456531 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01353714 0,04558626 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01353714 0,04551962 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01353714 0,04545316 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01353714 0,0453869 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01353714 0,04532084 ! response to tumor cell GO:0002347 12 7 0,000 0,01353714 0,04525497 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01353714 0,04518928 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01353714 0,04512379 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01353714 0,04505849 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01353714 0,04499338 ! diuresis GO:0030146 12 7 0,000 0,01353714 0,04492845 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01353714 0,04486371 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01353714 0,04479916 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01353714 0,04473479 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01353714 0,04467061 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01353714 0,04460661 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01353714 0,0445428 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01353714 0,04447917 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01353714 0,04441572 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01353714 0,04435245 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01353714 0,04428936 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01353714 0,04422644 ! lymph node development GO:0048535 9 7 0,000 0,01353714 0,04416371 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01353714 0,04410116 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01353714 0,04403878 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01353714 0,04397658 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01353714 0,04391455 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01353714 0,0438527 ! ATP catabolic process GO:0006200 10 7 0,000 0,01353714 0,04379102 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01353714 0,04372952 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01353714 0,04366819 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01353714 0,04360703 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01353714 0,04354604 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01353714 0,04348522 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01353714 0,04342457 ! muscle adaptation GO:0043500 12 7 0,000 0,01353714 0,04336409 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01353714 0,04330378 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01353714 0,04324363 ! retina homeostasis GO:0001895 9 7 0,000 0,01353714 0,04318366 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01353714 0,04312385 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01353714 0,0430642 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01353714 0,04300472 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01353714 0,0429454 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01353714 0,04288625 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01353714 0,04282726 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01353714 0,04276843 ! DNA recombination GO:0006310 146 92 1,000 0,01377654 0,04346509 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01406232 0,04430593 ! in utero embryonic development GO:0001701 147 96 1,000 0,01493504 0,04699123 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01545644 0,0485653 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01545644 0,04849905 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01545644 0,04843297 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01545644 0,04836708 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01545644 0,04830136 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01545644 0,04823582 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01545644 0,04817046 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01545644 0,04810528 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01545644 0,04804027 ! phosphate transport GO:0006817 10 8 0,000 0,01545644 0,04797544 ! N-glycan processing GO:0006491 12 8 0,000 0,01545644 0,04791079 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01545644 0,0478463 ! UTP metabolic process GO:0046051 8 8 0,000 0,01545644 0,04778199 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01545644 0,04771786 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01545644 0,04765389 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01545644 0,0475901 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01545644 0,04752647 ! succinate metabolic process GO:0006105 14 8 0,000 0,01545644 0,04746302 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01545644 0,04739974 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01545644 0,04733662 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01545644 0,04727367 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01545644 0,04721089 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01545644 0,04714828 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01545644 0,04708583 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01545644 0,04702355 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01545644 0,04696143 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01545644 0,04689948 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01545644 0,04683768 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01545644 0,04677606 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01545644 0,04671459 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01545644 0,04665328 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01545644 0,04659214 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01545644 0,04653116 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01545644 0,04647033 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01545644 0,04640966 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01545644 0,04634916 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01545644 0,04628881 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01545644 0,04622861 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01545644 0,04616858 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01545644 0,04610869 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01545644 0,04604897 ! melanin metabolic process GO:0006582 12 8 0,000 0,01545644 0,0459894 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01545644 0,04592998 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01545644 0,04587071 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01545644 0,0458116 ! macrophage activation GO:0042116 12 8 0,000 0,01545644 0,04575264 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01545644 0,04569383 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01545644 0,04563518 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01545644 0,04557667 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01545644 0,04551831 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01545644 0,04546011 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01545644 0,04540205 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01545644 0,04534414 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01545644 0,04528637 ! ruffle organization GO:0031529 11 8 0,000 0,01545644 0,04522876 ! osteoblast development GO:0002076 13 8 0,000 0,01545644 0,04517129 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01545644 0,04511396 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01545644 0,04505678 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01545644 0,04499975 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01545644 0,04494286 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01545644 0,04488611 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01545644 0,04482951 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01545644 0,04477305 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01545644 0,04471673 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01545644 0,04466056 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01545644 0,04460452 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01545644 0,04454863 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01545644 0,04449287 ! segment specification GO:0007379 10 8 0,000 0,01545644 0,04443725 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01545644 0,04438178 ! cellular extravasation GO:0045123 11 8 0,000 0,01545644 0,04432644 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01545644 0,04427124 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01545644 0,04421617 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01545644 0,04416125 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01545644 0,04410646 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01545644 0,0440518 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01545644 0,04399728 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01545644 0,0439429 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01545644 0,04388865 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01545644 0,04383453 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01545644 0,04378055 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01545644 0,04372669 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01545644 0,04367298 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01545644 0,04361939 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01545644 0,04356593 ! icosanoid secretion GO:0032309 12 8 0,000 0,01545644 0,04351261 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01545644 0,04345942 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01545644 0,04340635 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01545644 0,04335342 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01545644 0,04330061 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01545644 0,04324794 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01545644 0,04319539 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01545644 0,04314296 ! sterol catabolic process GO:0016127 9 8 0,000 0,01545644 0,04309067 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01545644 0,0430385 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01545644 0,04298646 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01545644 0,04293454 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01545644 0,04288275 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01545644 0,04283109 ! prophase GO:0051324 11 8 0,000 0,01545644 0,04277955 ! S phase GO:0051320 8 8 0,000 0,01545644 0,04272813 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01545644 0,04267683 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01545644 0,04262566 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01545644 0,04257461 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01545644 0,04252369 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01545644 0,04247288 ! hormone catabolic process GO:0042447 13 8 0,000 0,01545644 0,0424222 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01545644 0,04237164 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01545644 0,04232119 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01545644 0,04227087 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01545644 0,04222067 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01545644 0,04217058 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01545644 0,04212062 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01545644 0,04207077 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01545644 0,04202104 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01545644 0,04197143 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01545644 0,04192194 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01545644 0,04187256 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01545644 0,0418233 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01545644 0,04177415 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01545644 0,04172512 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01545644 0,0416762 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01545644 0,0416274 ! calcium ion transport GO:0006816 167 99 1,000 0,01583065 0,04258538 ! divalent metal ion transport GO:0070838 171 100 1,000 0,01613423 0,04335131 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01737211 0,04662293 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01737211 0,04656859 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01737211 0,04651438 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01737211 0,04646029 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01737211 0,04640633 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01737211 0,0463525 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01737211 0,04629879 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01737211 0,0462452 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01737211 0,04619174 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01737211 0,0461384 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01737211 0,04608518 ! GTP metabolic process GO:0046039 9 9 0,000 0,01737211 0,04603209 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01737211 0,04597912 ! social behavior GO:0035176 14 9 0,000 0,01737211 0,04592627 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01737211 0,04587354 ! artery development GO:0060840 19 9 0,000 0,01737211 0,04582093 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01737211 0,04576844 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01737211 0,04571608 ! response to pain GO:0048265 16 9 0,000 0,01737211 0,04566383 ! protein complex disassembly GO:0043241 17 9 0,000 0,01737211 0,0456117 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01737211 0,04555969 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01737211 0,0455078 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01737211 0,04545603 ! lung alveolus development GO:0048286 17 9 0,000 0,01737211 0,04540438 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01737211 0,04535284 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01737211 0,04530142 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01737211 0,04525012 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01737211 0,04519893 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01737211 0,04514786 ! protein targeting to ER GO:0045047 19 9 0,000 0,01737211 0,0450969 ! T cell selection GO:0045058 18 9 0,000 0,01737211 0,04504606 ! endoderm development GO:0007492 12 9 0,000 0,01737211 0,04499533 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01737211 0,04494472 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01737211 0,04489422 ! arginine catabolic process GO:0006527 10 9 0,000 0,01737211 0,04484383 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01737211 0,04479356 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01737211 0,0447434 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01737211 0,04469335 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01737211 0,04464341 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01737211 0,04459359 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01737211 0,04454387 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01737211 0,04449427 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01737211 0,04444477 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01737211 0,04439539 ! mannose metabolic process GO:0006013 9 9 0,000 0,01737211 0,04434612 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01737211 0,04429695 ! receptor clustering GO:0043113 15 9 0,000 0,01737211 0,0442479 ! epithelial cell development GO:0002064 10 9 0,000 0,01737211 0,04419895 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01737211 0,04415011 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01737211 0,04410138 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01737211 0,04405276 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01737211 0,04400424 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01737211 0,04395583 ! motor axon guidance GO:0008045 14 9 0,000 0,01737211 0,04390753 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01737211 0,04385933 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01737211 0,04381124 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01737211 0,04376326 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01737211 0,04371537 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01737211 0,0436676 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01737211 0,04361993 ! DNA ligation GO:0006266 14 9 0,000 0,01737211 0,04357236 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01737211 0,04352489 ! response to amine stimulus GO:0014075 13 9 0,000 0,01737211 0,04347753 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01737211 0,04343027 ! erythrocyte development GO:0048821 11 9 0,000 0,01737211 0,04338312 ! renal water homeostasis GO:0003091 14 9 0,000 0,01737211 0,04333607 ! mRNA cleavage GO:0006379 13 9 0,000 0,01737211 0,04328911 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01737211 0,04324226 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01737211 0,04319552 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01737211 0,04314887 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01737211 0,04310232 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01737211 0,04305588 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01737211 0,04300953 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01737211 0,04296328 ! acid secretion GO:0046717 14 9 0,000 0,01737211 0,04291713 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01737211 0,04287109 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01737211 0,04282514 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01737211 0,04277928 ! purine base metabolic process GO:0006144 18 9 0,000 0,01737211 0,04273353 ! oocyte differentiation GO:0009994 12 9 0,000 0,01737211 0,04268788 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01737211 0,04264232 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01737211 0,04259686 ! spleen development GO:0048536 15 9 0,000 0,01737211 0,04255149 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01737211 0,04250623 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01737211 0,04246105 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01737211 0,04241598 ! detection of calcium ion GO:0005513 13 9 0,000 0,01737211 0,042371 ! blastocyst formation GO:0001825 12 9 0,000 0,01737211 0,04232611 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01737211 0,04228133 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01737211 0,04223663 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01737211 0,04219203 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01737211 0,04214752 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01737211 0,04210311 ! prepulse inhibition GO:0060134 14 9 0,000 0,01737211 0,04205879 ! embryonic placenta development GO:0001892 12 9 0,000 0,01737211 0,04201457 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01737211 0,04197043 ! insulin secretion GO:0030073 17 9 0,000 0,01737211 0,04192639 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01737211 0,04188244 ! response to nicotine GO:0035094 16 9 0,000 0,01737211 0,04183859 ! nucleus localization GO:0051647 15 9 0,000 0,01737211 0,04179482 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01737211 0,04175115 ! localization within membrane GO:0051668 15 9 0,000 0,01737211 0,04170757 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01928417 0,04624982 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01928417 0,04620165 ! neuron fate specification GO:0048665 11 10 0,000 0,01928417 0,04615357 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01928417 0,04610559 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01928417 0,04605772 ! thyroid gland development GO:0030878 19 10 0,000 0,01928417 0,04600994 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01928417 0,04596226 ! synapsis GO:0007129 13 10 0,000 0,01928417 0,04591468 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01928417 0,0458672 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01928417 0,04581981 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01928417 0,04577253 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01928417 0,04572534 ! sulfate transport GO:0008272 12 10 0,000 0,01928417 0,04567825 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01928417 0,04563126 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01928417 0,04558436 ! androgen metabolic process GO:0008209 13 10 0,000 0,01928417 0,04553756 ! phospholipid efflux GO:0033700 16 10 0,000 0,01928417 0,04549085 ! hippocampus development GO:0021766 19 10 0,000 0,01928417 0,04544424 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01928417 0,04539773 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01928417 0,04535131 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01928417 0,04530498 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01928417 0,04525876 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01928417 0,04521262 GO:0010812|negative regulation of cell-substrate adhesion, ! pathogenesis GO:0009405 13 10 0,000 0,01928417 0,04516658 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01928417 0,04512063 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01928417 0,04507478 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01928417 0,04502902 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01928417 0,04498335 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01928417 0,04493777 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01928417 0,04489229 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01928417 0,0448469 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01928417 0,0448016 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01928417 0,04475639 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01928417 0,04471127 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01928417 0,04466624 ! response to X-ray GO:0010165 16 10 0,000 0,01928417 0,04462131 ! B cell proliferation GO:0042100 14 10 0,000 0,01928417 0,04457646 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01928417 0,04453171 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01928417 0,04448704 ! forebrain cell migration GO:0021885 17 10 0,000 0,01928417 0,04444247 ! lipid digestion GO:0044241 15 10 0,000 0,01928417 0,04439798 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01928417 0,04435358 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01928417 0,04430927 ! UV protection GO:0009650 14 10 0,000 0,01928417 0,04426505 ! entry into host cell GO:0030260 20 10 0,000 0,01928417 0,04422092 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01928417 0,04417687 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01928417 0,04413292 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01928417 0,04408905 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01928417 0,04404526 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01928417 0,04400157 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01928417 0,04395796 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01928417 0,04391444 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01928417 0,043871 ! regulation of organ growth GO:0046620 11 10 0,000 0,01928417 0,04382765 ! response to dsRNA GO:0043331 18 10 0,000 0,01928417 0,04378438 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01928417 0,0437412 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01928417 0,04369811 ! embryonic axis specification GO:0000578 12 10 0,000 0,01928417 0,0436551 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01928417 0,04361217 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01928417 0,04356933 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01928417 0,04352658 ! cranial nerve development GO:0021545 12 10 0,000 0,01928417 0,0434839 ! fucose catabolic process GO:0019317 16 10 0,000 0,01928417 0,04344131 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01928417 0,04339881 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01928417 0,04335638 ! protein sumoylation GO:0016925 12 10 0,000 0,01928417 0,04331404 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01928417 0,04327179 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01928417 0,04322961 ! zymogen activation GO:0031638 14 10 0,000 0,01928417 0,04318752 ! salivary gland development GO:0007431 22 10 0,000 0,01928417 0,04314551 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01928417 0,04310358 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01928417 0,04306173 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01928417 0,04301996 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01928417 0,04297828 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01928417 0,04293667 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01928417 0,04289515 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01928417 0,0428537 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01928417 0,04281234 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01928417 0,04277105 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01928417 0,04272985 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01928417 0,04268872 ! detection of bacterium GO:0016045 10 10 0,000 0,01928417 0,04264767 ! embryonic gut development GO:0048566 11 10 0,000 0,01928417 0,04260671 ! activation of innate immune response GO:0002218 10 10 0,000 0,01928417 0,04256582 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01928417 0,042525 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01928417 0,04248427 ! developmental induction GO:0031128 13 10 0,000 0,01928417 0,04244362 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01928417 0,04240304 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01928417 0,04236254 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01928417 0,04232212 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01928417 0,04228177 ! rRNA transcription GO:0009303 17 11 0,000 0,02119261 0,04642191 ! respiratory burst GO:0045730 14 11 0,000 0,02119261 0,04637774 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02119261 0,04633365 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02119261 0,04628965 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02119261 0,04624573 ! virus-host interaction GO:0019048 17 11 0,000 0,02119261 0,0462019 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02119261 0,04615815 ! filopodium assembly GO:0046847 19 11 0,000 0,02119261 0,04611448 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02119261 0,04607089 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02119261 0,04602739 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,02119261 0,04598396 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02119261 0,04594062 ! T cell proliferation GO:0042098 20 11 0,000 0,02119261 0,04589737 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02119261 0,04585419 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02119261 0,04581109 ! bone resorption GO:0045453 16 11 0,000 0,02119261 0,04576808 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02119261 0,04572514 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02119261 0,04568229 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02119261 0,04563951 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02119261 0,04559682 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02119261 0,04555421 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02119261 0,04551167 ! syncytium formation GO:0006949 15 11 0,000 0,02119261 0,04546922 ! plasma membrane organization GO:0007009 18 11 0,000 0,02119261 0,04542684 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02119261 0,04538455 ! focal adhesion formation GO:0048041 24 11 0,000 0,02119261 0,04534233 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02119261 0,04530019 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02119261 0,04525813 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02119261 0,04521614 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02119261 0,04517424 ! adult heart development GO:0007512 11 11 0,000 0,02119261 0,04513241 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02119261 0,04509066 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02119261 0,04504899 ! temperature homeostasis GO:0001659 16 11 0,000 0,02119261 0,04500739 ! L-glutamate transport GO:0015813 16 11 0,000 0,02119261 0,04496587 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02119261 0,04492443 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02119261 0,04488306 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02119261 0,04484177 ! stem cell development GO:0048864 29 11 0,000 0,02119261 0,04480055 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02119261 0,04475941 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02119261 0,04471835 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02119261 0,04467736 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02119261 0,04463645 ! vasoconstriction GO:0042310 15 11 0,000 0,02119261 0,04459561 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02119261 0,04455485 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02119261 0,04451416 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02119261 0,04447354 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02119261 0,044433 ! ribosome assembly GO:0042255 13 11 0,000 0,02119261 0,04439253 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02119261 0,04435214 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02119261 0,04431182 ! chromatin silencing GO:0006342 19 11 0,000 0,02119261 0,04427157 ! nucleosome positioning GO:0016584 13 11 0,000 0,02119261 0,0442314 ! T cell homeostasis GO:0043029 20 11 0,000 0,02119261 0,0441913 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02119261 0,04415127 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02119261 0,04411131 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02119261 0,04407143 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02119261 0,04403162 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02119261 0,04399188 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02119261 0,04395221 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02119261 0,04391261 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02119261 0,04387309 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02119261 0,04383363 ! male genitalia development GO:0030539 13 11 0,000 0,02119261 0,04379425 ! cholesterol efflux GO:0033344 19 11 0,000 0,02119261 0,04375494 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02119261 0,0437157 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02119261 0,04367653 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02119261 0,04363742 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02119261 0,04359839 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02119261 0,04355943 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02119261 0,04352054 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02119261 0,04348171 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02119261 0,04344296 ! lysogeny GO:0030069 18 11 0,000 0,02119261 0,04340428 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02119261 0,04336566 ! acrosome reaction GO:0007340 13 11 0,000 0,02119261 0,04332711 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02119261 0,04328863 ! lactation GO:0007595 20 12 0,000 0,02309745 0,04713765 ! reproductive cellular process GO:0048610 14 12 0,000 0,02309745 0,04709586 ! tRNA modification GO:0006400 14 12 0,000 0,02309745 0,04705415 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02309745 0,04701251 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02309745 0,04697094 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02309745 0,04692945 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02309745 0,04688803 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02309745 0,04684668 ! non-recombinational repair GO:0000726 19 12 0,000 0,02309745 0,0468054 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02309745 0,0467642 ! peroxisomal transport GO:0043574 21 12 0,000 0,02309745 0,04672307 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02309745 0,04668201 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02309745 0,04664103 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02309745 0,04660012 ! heart looping GO:0001947 15 12 0,000 0,02309745 0,04655928 ! palate development GO:0060021 15 12 0,000 0,02309745 0,04651851 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02309745 0,04647781 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02309745 0,04643718 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02309745 0,04639662 ! arginine metabolic process GO:0006525 13 12 0,000 0,02309745 0,04635614 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02309745 0,04631572 ! methionine metabolic process GO:0006555 13 12 0,000 0,02309745 0,04627538 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02309745 0,0462351 ! Golgi organization GO:0007030 18 12 0,000 0,02309745 0,0461949 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02309745 0,04615476 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02309745 0,0461147 ! monoamine transport GO:0015844 13 12 0,000 0,02309745 0,0460747 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02309745 0,04603478 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02309745 0,04599492 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02309745 0,04595513 ! L-amino acid transport GO:0015807 20 12 0,000 0,02309745 0,04591541 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02309745 0,04587576 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02309745 0,04583618 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02309745 0,04579667 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02309745 0,04575722 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02309745 0,04571784 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02309745 0,04567853 ! cerebellum development GO:0021549 13 12 0,000 0,02309745 0,04563929 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02309745 0,04560011 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02309745 0,04556101 ! histone acetylation GO:0016573 23 12 0,000 0,02309745 0,04552196 ! histone methylation GO:0016571 15 12 0,000 0,02309745 0,04548299 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02309745 0,04544408 ! gland morphogenesis GO:0022612 23 12 0,000 0,02309745 0,04540524 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02309745 0,04536647 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02309745 0,04532776 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02309745 0,04528912 ! response to gamma radiation GO:0010332 20 12 0,000 0,02309745 0,04525054 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02309745 0,04521203 ! intestinal absorption GO:0050892 19 12 0,000 0,02309745 0,04517358 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02309745 0,0451352 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02309745 0,04509689 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02309745 0,04505864 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02309745 0,04502045 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02309745 0,04498233 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02309745 0,04494427 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02309745 0,04490628 ! microspike assembly GO:0030035 23 12 0,000 0,02309745 0,04486836 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02309745 0,04483049 ! response to cold GO:0009409 14 12 0,000 0,02309745 0,04479269 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02499869 0,04843891 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02499869 0,04839814 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02499869 0,04835743 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02499869 0,0483168 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02499869 0,04827623 ! water transport GO:0006833 17 13 0,000 0,02499869 0,04823573 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02499869 0,0481953 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02499869 0,04815493 ! lipid localization GO:0010876 24 13 0,000 0,02499869 0,04811463 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02499869 0,0480744 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02499869 0,04803424 ! organelle fusion GO:0048284 28 13 0,000 0,02499869 0,04799415 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02499869 0,04795412 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02499869 0,04791416 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02499869 0,04787426 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02499869 0,04783443 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02499869 0,04779467 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02499869 0,04775497 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02499869 0,04771534 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02499869 0,04767578 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02499869 0,04763628 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02499869 0,04759684 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02499869 0,04755748 ! NAD metabolic process GO:0019674 21 13 0,000 0,02499869 0,04751817 ! exocrine system development GO:0035272 27 13 0,000 0,02499869 0,04747893 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02499869 0,04743976 ! bone mineralization GO:0030282 15 13 0,000 0,02499869 0,04740065 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02499869 0,0473616 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02499869 0,04732262 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02499869 0,04728371 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02499869 0,04724485 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02499869 0,04720607 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02499869 0,04716734 ! genitalia development GO:0048806 15 13 0,000 0,02499869 0,04712868 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02499869 0,04709008 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02499869 0,04705155 ! cellular pigmentation GO:0033059 24 13 0,000 0,02499869 0,04701307 ! tissue regeneration GO:0042246 21 13 0,000 0,02499869 0,04697466 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02499869 0,04693632 ! cofactor transport GO:0051181 19 13 0,000 0,02499869 0,04689803 ! NADP metabolic process GO:0006739 18 13 0,000 0,02499869 0,04685981 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02499869 0,04682165 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02499869 0,04678355 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02499869 0,04674552 ! gas transport GO:0015669 18 13 0,000 0,02499869 0,04670755 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02499869 0,04666963 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02499869 0,04663178 ! regulation of axon extension GO:0030516 23 13 0,000 0,02499869 0,04659399 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02499869 0,04655627 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02499869 0,0465186 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02499869 0,04648099 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02499869 0,04644345 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02499869 0,04640596 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02499869 0,04636854 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02689634 0,04984817 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02689634 0,04980804 ! superoxide anion generation GO:0042554 18 14 0,000 0,02689634 0,04976797 ! neuron maturation GO:0042551 21 14 0,000 0,02689634 0,04972796 ! regulation of S phase GO:0033261 18 14 0,000 0,02689634 0,04968802 ! myotube differentiation GO:0014902 21 14 0,000 0,02689634 0,04964814 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02689634 0,04960833 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02689634 0,04956858 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02689634 0,04952889 ! inositol metabolic process GO:0006020 20 14 0,000 0,02689634 0,04948927 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02689634 0,04944971 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02689634 0,04941021 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02689634 0,04937078 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02689634 0,04933141 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02689634 0,0492921 ! response to cAMP GO:0051591 19 14 0,000 0,02689634 0,04925285 ! limbic system development GO:0021761 25 14 0,000 0,02689634 0,04921367 ! startle response GO:0001964 21 14 0,000 0,02689634 0,04917455 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02689634 0,04913549 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02689634 0,04909649 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02689634 0,04905756 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02689634 0,04901869 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02689634 0,04897988 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02689634 0,04894113 ! glycine metabolic process GO:0006544 22 14 0,000 0,02689634 0,04890244 ! pituitary gland development GO:0021983 23 14 0,000 0,02689634 0,04886381 ! cellular response to starvation GO:0009267 21 14 0,000 0,02689634 0,04882524 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02689634 0,04878674 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02689634 0,04874829 ! regulation of heart rate GO:0002027 23 14 0,000 0,02689634 0,04870991 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02689634 0,04867158 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02689634 0,04863332 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02689634 0,04859512 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02689634 0,04855697 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02689634 0,04851889 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02689634 0,04848086 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02689634 0,0484429 ! axon cargo transport GO:0008088 27 14 0,000 0,02689634 0,04840499 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02689634 0,04836715 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02689634 0,04832936 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02689634 0,04829163 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02689634 0,04825396 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02689634 0,04821635 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02689634 0,0481788 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02689634 0,04814131 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02689634 0,04810387 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02689634 0,0480665 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02689634 0,04802918 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02689634 0,04799192 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02689634 0,04795472 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02689634 0,04791757 ! muscle maintenance GO:0046716 19 14 0,000 0,02689634 0,04788048 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02689634 0,04784345 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02689634 0,04780648 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02689634 0,04776956 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02689634 0,0477327 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02689634 0,0476959 ! cilium assembly GO:0042384 20 14 0,000 0,02689634 0,04765915 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02689634 0,04762247 ! metencephalon development GO:0022037 19 15 0,000 0,02879041 0,05093687 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02879041 0,05089772 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02879041 0,05085863 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02879041 0,05081959 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02879041 0,05078062 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02879041 0,05074171 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02879041 0,05070286 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02879041 0,05066406 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02879041 0,05062533 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02879041 0,05058666 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02879041 0,05054804 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02879041 0,05050948 ! adult walking behavior GO:0007628 25 15 0,000 0,02879041 0,05047098 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02879041 0,05043255 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02879041 0,05039416 ! myoblast differentiation GO:0045445 27 15 0,000 0,02879041 0,05035584 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02879041 0,05031758 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02879041 0,05027937 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02879041 0,05024122 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02879041 0,05020313 ! cerebral cortex development GO:0021987 29 15 0,000 0,02879041 0,0501651 ! response to osmotic stress GO:0006970 22 15 0,000 0,02879041 0,05012712 ! vesicle coating GO:0006901 25 15 0,000 0,02879041 0,05008921 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02879041 0,05005135 ! DNA integration GO:0015074 22 15 0,000 0,02879041 0,05001354 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02879041 0,0499758 ! peptide secretion GO:0002790 27 15 0,000 0,02879041 0,04993811 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02879041 0,04990048 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02879041 0,0498629 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02879041 0,04982538 ! neuron recognition GO:0008038 22 15 0,000 0,02879041 0,04978792 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02879041 0,04975051 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02879041 0,04971316 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02879041 0,04967587 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02879041 0,04963863 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02879041 0,04960145 ! biomineral formation GO:0031214 18 15 0,000 0,02879041 0,04956432 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02879041 0,04952725 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02879041 0,04949023 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02879041 0,04945327 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02879041 0,04941637 ! organic cation transport GO:0015695 19 15 0,000 0,02879041 0,04937952 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02879041 0,04934272 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02879041 0,04930598 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02879041 0,04926929 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02879041 0,04923266 ! defense response to virus GO:0051607 27 15 0,000 0,02879041 0,04919609 ! peptide hormone processing GO:0016486 19 15 0,000 0,02879041 0,04915956 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02879041 0,04912309 ! protein secretion GO:0009306 27 16 0,000 0,03068089 0,0523099 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03068089 0,05227115 ! hormone secretion GO:0046879 25 16 0,000 0,03068089 0,05223246 ! bone remodeling GO:0046849 24 16 0,000 0,03068089 0,05219382 ! endothelial cell migration GO:0043542 22 16 0,000 0,03068089 0,05215525 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03068089 0,05211673 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03068089 0,05207827 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03068089 0,05203986 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03068089 0,05200151 ! glial cell development GO:0021782 24 16 0,000 0,03068089 0,05196322 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03068089 0,05192498 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03068089 0,0518868 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03068089 0,05184868 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03068089 0,05181061 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03068089 0,0517726 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03068089 0,05173464 ! regulation of protein binding GO:0043393 27 16 0,000 0,03068089 0,05169674 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03068089 0,05165889 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03068089 0,0516211 ! protein export from nucleus GO:0006611 24 16 0,000 0,03068089 0,05158337 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03068089 0,05154569 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03068089 0,05150807 ! DNA replication initiation GO:0006270 25 16 0,000 0,03068089 0,0514705 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03068089 0,05143298 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03068089 0,05139552 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03068089 0,05135812 ! diencephalon development GO:0021536 25 16 0,000 0,03068089 0,05132076 ! oogenesis GO:0048477 23 16 0,000 0,03068089 0,05128347 ! neural crest cell migration GO:0001755 24 16 0,000 0,03068089 0,05124622 ! G1 phase GO:0051318 27 16 0,000 0,03068089 0,05120904 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03068089 0,0511719 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03068089 0,05113482 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03068089 0,05109779 ! steroid catabolic process GO:0006706 22 16 0,000 0,03068089 0,05106082 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03068089 0,0510239 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03068089 0,05098703 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03068089 0,05095022 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03068089 0,05091346 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03068089 0,05087675 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03068089 0,05084009 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03068089 0,05080349 ! nerve development GO:0021675 18 16 0,000 0,03068089 0,05076694 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03068089 0,05073045 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03068089 0,050694 ! negative regulation of translation GO:0017148 22 16 0,000 0,03068089 0,05065761 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03256781 0,05373454 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03256781 0,05369602 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03256781 0,05365756 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03256781 0,05361915 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03256781 0,0535808 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03256781 0,0535425 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03256781 0,05350425 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03256781 0,05346606 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03256781 0,05342793 ! signal complex assembly GO:0007172 29 17 0,000 0,03256781 0,05338985 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03256781 0,05335182 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03256781 0,05331385 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03256781 0,05327593 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03256781 0,05323806 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03256781 0,05320025 ! memory GO:0007613 25 17 0,000 0,03256781 0,05316249 ! keratinization GO:0031424 17 17 0,000 0,03256781 0,05312479 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03256781 0,05308714 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03256781 0,05304954 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03256781 0,053012 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,03256781 0,05297451 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03256781 0,05293707 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03256781 0,05289968 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03256781 0,05286235 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03256781 0,05282507 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03256781 0,05278785 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03256781 0,05275067 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03256781 0,05271355 ! heme metabolic process GO:0042168 27 17 0,000 0,03256781 0,05267648 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03256781 0,05263946 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03256781 0,0526025 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03256781 0,05256558 ! body fluid secretion GO:0007589 27 17 0,000 0,03256781 0,05252872 ! stem cell differentiation GO:0048863 36 17 0,000 0,03256781 0,05249191 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03256781 0,05245515 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03256781 0,05241844 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03256781 0,05238179 ! sensory perception of pain GO:0019233 23 17 0,000 0,03256781 0,05234518 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03256781 0,05230863 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03256781 0,05227212 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03256781 0,05223567 ! synaptogenesis GO:0007416 24 17 0,000 0,03256781 0,05219927 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03256781 0,05216292 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03256781 0,05212662 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03256781 0,05209037 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03256781 0,05205417 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03256781 0,05201802 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03256781 0,05198193 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03256781 0,05194588 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03256781 0,05190988 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03256781 0,05187393 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03445116 0,05483575 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03445116 0,05479783 ! positive regulation of translation GO:0045727 28 18 0,000 0,03445116 0,05475996 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03445116 0,05472214 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03445116 0,05468437 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03445116 0,05464666 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03445116 0,054609 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03445116 0,05457139 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03445116 0,05453383 ! axis specification GO:0009798 26 18 0,000 0,03445116 0,05449633 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03445116 0,05445887 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03445116 0,05442147 ! pancreas development GO:0031016 26 18 0,000 0,03445116 0,05438412 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03445116 0,05434682 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03445116 0,05430957 ! response to retinoic acid GO:0032526 25 18 0,000 0,03445116 0,05427237 ! pigmentation during development GO:0048066 31 18 0,000 0,03445116 0,05423522 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03445116 0,05419812 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03445116 0,05416108 ! fucose metabolic process GO:0006004 26 18 0,000 0,03445116 0,05412408 ! response to fungus GO:0009620 19 18 0,000 0,03445116 0,05408714 ! peptide cross-linking GO:0018149 31 18 0,000 0,03445116 0,05405024 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03445116 0,0540134 ! heart process GO:0003015 27 18 0,000 0,03445116 0,05397661 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03445116 0,05393986 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03445116 0,05390317 ! visual learning GO:0008542 35 18 0,000 0,03445116 0,05386652 ! somitogenesis GO:0001756 24 18 0,000 0,03445116 0,05382993 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03445116 0,05379339 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03445116 0,05375689 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03445116 0,05372045 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03445116 0,05368405 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03445116 0,0536477 ! vitamin transport GO:0051180 24 18 0,000 0,03445116 0,05361141 ! hormone transport GO:0009914 27 18 0,000 0,03445116 0,05357516 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03445116 0,05353896 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03445116 0,05350281 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03445116 0,05346671 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03445116 0,05343065 ! cell-cell recognition GO:0009988 20 18 0,000 0,03445116 0,05339465 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03445116 0,05335869 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03445116 0,05332278 ! regulation of glucose import GO:0046324 21 18 0,000 0,03445116 0,05328692 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03445116 0,05325111 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03445116 0,05321535 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03445116 0,05317964 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03445116 0,05314397 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03633095 0,05600615 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03633095 0,05596864 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03633095 0,05593117 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03633095 0,05589376 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03633095 0,0558564 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03633095 0,05581909 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03633095 0,05578183 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03633095 0,05574461 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03633095 0,05570745 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03633095 0,05567034 ! regeneration GO:0031099 32 19 0,000 0,03633095 0,05563327 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03633095 0,05559626 ! response to alkaloid GO:0043279 32 19 0,000 0,03633095 0,05555929 ! sensory perception of taste GO:0050909 23 19 0,000 0,03633095 0,05552238 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03633095 0,05548551 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03633095 0,05544869 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03633095 0,05541192 ! peroxisome organization GO:0007031 29 19 0,000 0,03633095 0,0553752 ! digestive system process GO:0022600 30 19 0,000 0,03633095 0,05533853 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03633095 0,0553019 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03633095 0,05526533 ! response to vitamin A GO:0033189 26 19 0,000 0,03633095 0,0552288 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03633095 0,05519232 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03633095 0,05515589 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03633095 0,05511951 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03633095 0,05508317 ! response to starvation GO:0042594 30 19 0,000 0,03633095 0,05504689 ! sex determination GO:0007530 29 19 0,000 0,03633095 0,05501065 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03633095 0,05497446 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03633095 0,05493831 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03633095 0,05490222 ! cytolysis GO:0019835 20 19 0,000 0,03633095 0,05486617 ! renal system process GO:0003014 35 19 0,000 0,03633095 0,05483017 ! vasodilation GO:0042311 33 19 0,000 0,03633095 0,05479421 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03633095 0,05475831 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03633095 0,05472245 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03633095 0,05468663 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03633095 0,05465087 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03633095 0,05461515 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03633095 0,05457947 ! sarcomere organization GO:0045214 23 19 0,000 0,03633095 0,05454385 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03633095 0,05450827 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03633095 0,05447273 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03633095 0,05443725 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03633095 0,05440181 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03633095 0,05436641 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03633095 0,05433106 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03633095 0,05429576 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03633095 0,0542605 ! protein stabilization GO:0050821 26 19 0,000 0,03633095 0,05422529 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03820718 0,05698867 ! iron ion transport GO:0006826 37 20 0,000 0,03820718 0,05695173 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03820718 0,05691485 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03820718 0,05687801 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03820718 0,05684122 ! response to vitamin GO:0033273 29 20 0,000 0,03820718 0,05680448 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03820718 0,05676778 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03820718 0,05673113 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03820718 0,05669453 ! spinal cord development GO:0021510 31 20 0,000 0,03820718 0,05665798 ! response to ethanol GO:0045471 37 20 0,000 0,03820718 0,05662147 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03820718 0,05658501 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03820718 0,0565486 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03820718 0,05651223 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03820718 0,05647591 ! chromosome condensation GO:0030261 31 20 0,000 0,03820718 0,05643964 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03820718 0,05640342 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03820718 0,05636724 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03820718 0,0563311 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03820718 0,05629502 ! pallium development GO:0021543 38 20 0,000 0,03820718 0,05625898 ! DNA modification GO:0006304 28 20 0,000 0,03820718 0,05622298 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03820718 0,05618704 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03820718 0,05615113 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03820718 0,05611528 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03820718 0,05607947 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03820718 0,0560437 ! collagen catabolic process GO:0030574 25 20 0,000 0,03820718 0,05600798 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03820718 0,05597231 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03820718 0,05593668 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03820718 0,0559011 ! actin filament-based movement GO:0030048 34 20 0,000 0,03820718 0,05586556 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04007988 0,05856653 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04007988 0,05852934 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04007988 0,05849221 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04007988 0,05845511 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04007988 0,05841807 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04007988 0,05838107 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04007988 0,05834412 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04007988 0,05830722 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04007988 0,05827036 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04007988 0,05823355 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04007988 0,05819679 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04007988 0,05816007 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04007988 0,0581234 ! vesicle docking GO:0048278 27 21 0,000 0,04007988 0,05808678 ! phototransduction GO:0007602 25 21 0,000 0,04007988 0,0580502 ! dendrite development GO:0016358 35 21 0,000 0,04007988 0,05801367 ! visual behavior GO:0007632 39 21 0,000 0,04007988 0,05797718 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04007988 0,05794074 ! ovarian follicle development GO:0001541 30 21 0,000 0,04007988 0,05790434 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04007988 0,05786799 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04007988 0,05783169 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04007988 0,05779543 ! cell aging GO:0007569 32 21 0,000 0,04007988 0,05775922 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04007988 0,05772305 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04007988 0,05768693 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04007988 0,05765085 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04007988 0,05761482 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04007988 0,05757884 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04007988 0,05754289 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04007988 0,057507 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04007988 0,05747114 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04007988 0,05743534 ! fatty acid transport GO:0015908 30 21 0,000 0,04007988 0,05739957 ! immunoglobulin production GO:0002377 33 21 0,000 0,04007988 0,05736386 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04007988 0,05732818 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04007988 0,05729255 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04007988 0,05725697 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04007988 0,05722143 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04007988 0,05718593 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04007988 0,05715047 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04007988 0,05711507 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04007988 0,0570797 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04007988 0,05704438 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04007988 0,0570091 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04007988 0,05697387 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04007988 0,05693868 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04007988 0,05690353 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04194903 0,05952052 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04194903 0,05948383 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04194903 0,05944718 ! viral genome replication GO:0019079 29 22 0,000 0,04194903 0,05941057 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04194903 0,05937401 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04194903 0,0593375 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04194903 0,05930103 ! molting cycle process GO:0022404 40 22 0,000 0,04194903 0,0592646 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04194903 0,05922822 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04194903 0,05919188 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04194903 0,05915559 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04194903 0,05911934 ! vasculogenesis GO:0001570 33 22 0,000 0,04194903 0,05908314 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04194903 0,05904698 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04194903 0,05901087 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04194903 0,0589748 ! lysosome organization GO:0007040 37 22 0,000 0,04194903 0,05893877 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04194903 0,05890279 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04194903 0,05886685 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04194903 0,05883096 ! regulation of behavior GO:0050795 38 22 0,000 0,04194903 0,05879511 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04194903 0,0587593 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04194903 0,05872354 ! membrane depolarization GO:0051899 35 22 0,000 0,04194903 0,05868782 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04194903 0,05865214 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04194903 0,05861651 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,04194903 0,05858092 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04194903 0,05854537 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04194903 0,05850987 ! blastocyst development GO:0001824 37 22 0,000 0,04194903 0,0584744 ! neural tube closure GO:0001843 33 22 0,000 0,04194903 0,05843899 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04194903 0,05840361 ! protein tetramerization GO:0051262 39 22 0,000 0,04194903 0,05836828 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04381465 0,06092726 ! neuron fate commitment GO:0048663 32 23 0,000 0,04381465 0,06089045 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04381465 0,06085368 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04381465 0,06081696 ! myelination GO:0042552 35 23 0,000 0,04381465 0,06078027 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04381465 0,06074364 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04381465 0,06070705 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04381465 0,0606705 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04381465 0,06063399 ! vesicle targeting GO:0006903 32 23 0,000 0,04381465 0,06059753 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04381465 0,06056111 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04381465 0,06052474 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04381465 0,06048841 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04381465 0,06045213 ! interaction with host GO:0051701 37 23 0,000 0,04381465 0,06041588 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04381465 0,06037969 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04381465 0,06034353 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04381465 0,06030742 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04381465 0,06027135 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04381465 0,06023532 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04381465 0,06019934 ! cell fate determination GO:0001709 45 23 0,000 0,04381465 0,0601634 ! pentose metabolic process GO:0019321 31 23 0,000 0,04381465 0,0601275 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04381465 0,06009165 ! spermatid development GO:0007286 33 23 0,000 0,04381465 0,06005584 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04381465 0,06002007 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04381465 0,05998434 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04381465 0,05994866 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04381465 0,05991302 ! telomere organization GO:0032200 32 23 0,000 0,04381465 0,05987742 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04381465 0,05984186 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04381465 0,05980635 ! regulation of amine transport GO:0051952 38 23 0,000 0,04381465 0,05977087 ! liver development GO:0001889 40 23 0,000 0,04381465 0,05973544 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04567674 0,06223727 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04567674 0,06220042 ! initiation of viral infection GO:0019059 42 24 0,000 0,04567674 0,06216362 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04567674 0,06212686 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04567674 0,06209014 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04567674 0,06205346 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04567674 0,06201683 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04567674 0,06198024 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04567674 0,0619437 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04567674 0,0619072 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04567674 0,06187074 ! vacuole organization GO:0007033 39 24 0,000 0,04567674 0,06183432 ! receptor metabolic process GO:0043112 37 24 0,000 0,04567674 0,06179795 ! neural crest cell development GO:0014032 39 24 0,000 0,04567674 0,06176162 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04567674 0,06172533 ! primary neural tube formation GO:0014020 35 24 0,000 0,04567674 0,06168909 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04567674 0,06165288 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04567674 0,06161672 ! base-excision repair GO:0006284 31 24 0,000 0,04567674 0,0615806 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04567674 0,06154453 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04567674 0,0615085 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04567674 0,06147251 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04567674 0,06143656 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04567674 0,06140065 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04567674 0,06136478 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04567674 0,06132896 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04753532 0,06378718 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04753532 0,06374999 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04753532 0,06371284 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04753532 0,06367573 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04753532 0,06363867 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04753532 0,06360165 ! peptide transport GO:0015833 43 25 0,000 0,04753532 0,06356467 ! male gonad development GO:0008584 33 25 0,000 0,04753532 0,06352774 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04753532 0,06349084 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04753532 0,06345399 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04753532 0,06341719 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04753532 0,06338042 ! phospholipid transport GO:0015914 35 25 0,000 0,04753532 0,0633437 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04753532 0,06330703 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04753532 0,06327039 ! detection of light stimulus GO:0009583 30 25 0,000 0,04753532 0,0632338 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04753532 0,06319724 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04753532 0,06316074 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04753532 0,06312427 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04753532 0,06308784 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04939038 0,06551204 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04939038 0,06547428 ! translational initiation GO:0006413 43 26 0,000 0,04939038 0,06543656 ! regulation of pH GO:0006885 36 26 0,000 0,04939038 0,06539889 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,04939038 0,06536126 ! circadian rhythm GO:0007623 42 26 0,000 0,04939038 0,06532368 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04939038 0,06528613 ! post-embryonic development GO:0009791 42 26 0,000 0,04939038 0,06524863 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04939038 0,06521118 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04939038 0,06517377 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04939038 0,0651364 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04939038 0,06509907 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04939038 0,06506178 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04939038 0,06502454 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04939038 0,06498734 ! regulation of coagulation GO:0050818 39 26 0,000 0,04939038 0,06495018 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05124193 0,06734654 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05124193 0,06730808 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05124193 0,06726966 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05124193 0,06723129 ! membrane docking GO:0022406 39 27 0,000 0,05124193 0,06719296 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05124193 0,06715467 ! catechol metabolic process GO:0009712 43 27 0,000 0,05124193 0,06711643 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05124193 0,06707823 ! acute-phase response GO:0006953 42 27 0,000 0,05124193 0,06704007 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05124193 0,06700196 ! myofibril assembly GO:0030239 36 27 0,000 0,05124193 0,06696389 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05124193 0,06692586 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05124193 0,06688788 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05124193 0,06684994 ! natural killer cell activation GO:0030101 35 27 0,000 0,05124193 0,06681204 ! lipid oxidation GO:0034440 38 27 0,000 0,05124193 0,06677419 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05124193 0,06673638 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05124193 0,06669861 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05124193 0,06666089 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05124193 0,0666232 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05124193 0,06658556 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05124193 0,06654797 ! gene silencing GO:0016458 41 27 0,000 0,05124193 0,06651041 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05308999 0,06887026 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05308999 0,06883144 ! phenol metabolic process GO:0018958 44 28 0,000 0,05308999 0,06879266 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05308999 0,06875392 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05308999 0,06871523 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05308999 0,06867659 ! cell junction assembly GO:0034329 56 28 0,000 0,05308999 0,06863798 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05308999 0,06859942 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05308999 0,0685609 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05308999 0,06852243 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05308999 0,068484 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05308999 0,06844561 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05308999 0,06840727 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05308999 0,06836896 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05308999 0,06833071 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05308999 0,06829249 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05308999 0,06825432 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05308999 0,06821618 ! mesoderm formation GO:0001707 46 28 0,000 0,05308999 0,0681781 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05308999 0,06814005 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,05308999 0,06810205 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05308999 0,06806409 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05308999 0,06802617 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05308999 0,06798829 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05308999 0,06795046 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05308999 0,06791266 ! neural tube formation GO:0001841 41 28 0,000 0,05308999 0,06787491 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05308999 0,06783721 ! placenta development GO:0001890 37 28 0,000 0,05308999 0,06779954 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05493455 0,07011624 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05493455 0,07007735 ! ovulation cycle process GO:0022602 41 29 0,000 0,05493455 0,0700385 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05493455 0,0699997 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05493455 0,06996094 ! mismatch repair GO:0006298 34 29 0,000 0,05493455 0,06992222 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05493455 0,06988355 ! muscle cell development GO:0055001 38 29 0,000 0,05493455 0,06984492 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05493455 0,06980633 ! telencephalon development GO:0021537 52 29 0,000 0,05493455 0,06976778 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05493455 0,06972928 ! tissue homeostasis GO:0001894 42 29 0,000 0,05493455 0,06969082 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05677562 0,07198673 ! collagen metabolic process GO:0032963 40 30 0,000 0,05677562 0,07194706 ! organic anion transport GO:0015711 51 30 0,000 0,05677562 0,07190745 ! cholesterol transport GO:0030301 46 30 0,000 0,05677562 0,07186787 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05677562 0,07182834 ! spliceosome assembly GO:0000245 49 30 0,000 0,05677562 0,07178885 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05677562 0,07174941 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05677562 0,07171001 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05677562 0,07167065 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05677562 0,07163133 ! ovulation cycle GO:0042698 43 30 0,000 0,05677562 0,07159206 ! hindbrain development GO:0030902 45 30 0,000 0,05677562 0,07155283 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05677562 0,07151365 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05677562 0,07147451 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05677562 0,07143541 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05677562 0,07139635 ! response to heat GO:0009408 41 30 0,000 0,05677562 0,07135733 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05677562 0,07131836 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05677562 0,07127943 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05861321 0,07354631 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05861321 0,07350621 ! mammary gland development GO:0030879 57 31 0,000 0,05861321 0,07346615 ! glial cell differentiation GO:0010001 55 31 0,000 0,05861321 0,07342613 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05861321 0,07338616 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05861321 0,07334624 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05861321 0,07330635 ! odontogenesis GO:0042476 50 31 0,000 0,05861321 0,07326651 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05861321 0,07322671 ! segmentation GO:0035282 41 31 0,000 0,05861321 0,07318696 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05861321 0,07314725 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05861321 0,07310758 ! metanephros development GO:0001656 58 31 0,000 0,05861321 0,07306796 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05861321 0,07302837 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05861321 0,07298884 ! cell fate specification GO:0001708 37 31 0,000 0,05861321 0,07294934 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05861321 0,07290989 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05861321 0,07287048 ! RNA modification GO:0009451 40 31 0,000 0,05861321 0,07283111 ! regulation of muscle development GO:0048634 48 32 0,000 0,06044732 0,07506957 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06044732 0,07502906 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06044732 0,07498859 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06044732 0,07494816 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06044732 0,07490778 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06044732 0,07486745 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,06044732 0,07482715 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06044732 0,0747869 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06044732 0,07474669 ! regulation of protein stability GO:0031647 48 32 0,000 0,06044732 0,07470653 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,06044732 0,0746664 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06044732 0,07462633 ! cytokine production GO:0001816 44 32 0,000 0,06044732 0,07458629 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06044732 0,0745463 ! vesicle localization GO:0051648 47 32 0,000 0,06044732 0,07450635 ! RNA export from nucleus GO:0006405 44 33 0,000 0,06227797 0,07672166 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06227797 0,07668059 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06227797 0,07663956 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06227797 0,07659857 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06227797 0,07655763 ! ear morphogenesis GO:0042471 42 33 0,000 0,06227797 0,07651674 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06227797 0,07647589 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06227797 0,07643508 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06227797 0,07639431 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06227797 0,07635359 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06227797 0,07631291 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06227797 0,07627228 ! female gonad development GO:0008585 49 33 0,000 0,06227797 0,07623168 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06227797 0,07619114 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06227797 0,07615063 ! lipid homeostasis GO:0055088 55 33 0,000 0,06227797 0,07611017 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06227797 0,07606975 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06227797 0,07602937 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06227797 0,07598904 ! cytokinesis GO:0000910 52 33 0,000 0,06227797 0,07594875 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06227797 0,0759085 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06410516 0,07809421 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06410516 0,07805286 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06410516 0,07801157 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06410516 0,07797031 ! feeding behavior GO:0007631 45 34 0,000 0,06410516 0,0779291 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06410516 0,07788793 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06410516 0,07784681 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06410516 0,07780573 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06410516 0,07776469 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06410516 0,0777237 ! neuron migration GO:0001764 46 34 0,000 0,06410516 0,07768275 ! female gamete generation GO:0007292 43 34 0,000 0,06410516 0,07764184 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06410516 0,07760098 ! aerobic respiration GO:0009060 47 34 0,000 0,06410516 0,07756016 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06410516 0,07751938 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,06410516 0,07747864 ! embryonic organ development GO:0048568 45 34 0,000 0,06410516 0,07743795 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06410516 0,0773973 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06592889 0,07955742 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06592889 0,0795157 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06592889 0,07947402 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06592889 0,07943239 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06592889 0,0793908 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06592889 0,07934926 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06592889 0,07930776 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06592889 0,0792663 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06592889 0,07922489 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06592889 0,07918352 ! glycogen metabolic process GO:0005977 48 35 0,000 0,06592889 0,07914219 ! pigment metabolic process GO:0042440 61 35 0,000 0,06592889 0,07910091 ! protein homooligomerization GO:0051260 52 35 0,000 0,06592889 0,07905966 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06774916 0,08120015 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06774916 0,08115785 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06774916 0,08111561 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06774916 0,0810734 ! negative regulation of binding GO:0051100 58 36 0,000 0,06774916 0,08103124 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06774916 0,08098913 ! tissue remodeling GO:0048771 62 36 0,000 0,06774916 0,08094705 ! neural tube development GO:0021915 50 36 0,000 0,06774916 0,08090503 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06774916 0,08086304 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06774916 0,0808211 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06774916 0,0807792 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06774916 0,08073735 ! glucan metabolic process GO:0044042 49 36 0,000 0,06774916 0,08069554 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,069566 0,08281667 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,069566 0,08277382 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,069566 0,08273103 ! learning GO:0007612 67 37 0,000 0,069566 0,08268827 ! ion transmembrane transport GO:0034220 56 37 0,000 0,069566 0,08264556 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,069566 0,08260289 ! regulation of protein secretion GO:0050708 51 37 0,000 0,069566 0,08256027 ! amino acid activation GO:0043038 52 37 0,000 0,069566 0,08251769 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,069566 0,08247516 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,0713794 0,08458146 ! gliogenesis GO:0042063 71 38 0,000 0,0713794 0,08453791 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,0713794 0,0844944 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0713794 0,08445094 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0713794 0,08440752 ! phagocytosis GO:0006909 60 38 0,000 0,0713794 0,08436414 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0713794 0,08432081 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0713794 0,08427753 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0713794 0,08423429 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,07318937 0,08632592 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,07318937 0,08628168 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,07318937 0,08623747 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,07318937 0,08619332 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,07318937 0,08614921 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,07318937 0,08610514 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,07318937 0,08606112 ! male sex differentiation GO:0046661 53 39 0,000 0,07318937 0,08601714 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,07318937 0,08597321 ! chromatin remodeling GO:0006338 68 39 0,000 0,07318937 0,08592933 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,07318937 0,08588549 ! developmental growth GO:0048589 62 39 0,000 0,07318937 0,08584169 ! cell growth GO:0016049 61 39 0,000 0,07318937 0,08579794 ! synapse organization GO:0050808 55 39 0,000 0,07318937 0,08575423 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07499591 0,08782617 ! regulation of tube size GO:0035150 60 40 0,000 0,07499591 0,08778148 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07499591 0,08773683 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07499591 0,08769222 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07499591 0,08764766 ! peptide metabolic process GO:0006518 56 40 0,000 0,07499591 0,08760315 ! inner ear development GO:0048839 57 40 0,000 0,07499591 0,08755868 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07499591 0,08751426 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07499591 0,08746988 ! B cell differentiation GO:0030183 62 40 0,000 0,07499591 0,08742555 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07499591 0,08738126 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07499591 0,08733701 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07679904 0,0893916 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07679904 0,08934638 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,07679904 0,08930121 ! glucose transport GO:0015758 52 41 0,000 0,07679904 0,08925609 ! endosome transport GO:0016197 71 41 0,000 0,07679904 0,08921101 ! striated muscle contraction GO:0006941 62 41 0,000 0,07679904 0,08916597 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07679904 0,08912099 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07679904 0,08907604 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07679904 0,08903115 ! biopolymer methylation GO:0043414 62 41 0,000 0,07679904 0,0889863 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07679904 0,08894149 ! mitochondrial transport GO:0006839 60 42 0,000 0,07859876 0,09097994 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,07859876 0,09093418 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,07859876 0,09088846 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,07859876 0,09084278 ! cellular component disassembly GO:0022411 64 42 0,000 0,07859876 0,09079716 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,07859876 0,09075158 ! hexose transport GO:0008645 54 42 0,000 0,07859876 0,09070604 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,07859876 0,09066055 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,07859876 0,09061511 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,07859876 0,09056971 ! excretion GO:0007588 63 42 0,000 0,07859876 0,09052436 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,07859876 0,09047905 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,07859876 0,09043379 ! regulation of cell shape GO:0008360 78 42 0,000 0,07859876 0,09038857 ! positive regulation of binding GO:0051099 59 43 0,000 0,08039507 0,09240812 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08039507 0,09236196 ! leukocyte migration GO:0050900 60 43 0,000 0,08039507 0,09231585 ! neuromuscular process GO:0050905 79 43 0,000 0,08039507 0,09226979 ! activation of caspase activity GO:0006919 65 43 0,000 0,08039507 0,09222377 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08039507 0,09217779 ! tRNA processing GO:0008033 49 43 0,000 0,08039507 0,09213187 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,08039507 0,09208598 ! response to insulin stimulus GO:0032868 63 43 0,000 0,08039507 0,09204015 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08039507 0,09199435 ! methylation GO:0032259 64 43 0,000 0,08039507 0,09194861 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,08218798 0,09395246 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,08218798 0,09390579 ! glycolysis GO:0006096 53 44 0,000 0,08218798 0,09385916 ! regulation of action potential GO:0001508 71 44 0,000 0,08218798 0,09381258 ! regulation of ion transport GO:0043269 57 44 0,000 0,08218798 0,09376605 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,08218798 0,09371956 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,08218798 0,09367312 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,08218798 0,09362672 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,08218798 0,09358037 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,08218798 0,09353407 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,08218798 0,09348781 ! RNA catabolic process GO:0006401 64 45 0,000 0,08397749 0,09547614 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08397749 0,09542897 ! regulation of translational initiation GO:0006446 64 45 0,000 0,08397749 0,09538185 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08397749 0,09533477 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08397749 0,09528773 ! cell recognition GO:0008037 58 45 0,000 0,08397749 0,09524075 ! cell maturation GO:0048469 60 45 0,000 0,08397749 0,09519381 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,08397749 0,09514692 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,08576363 0,09712277 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,08576363 0,09707497 ! cell redox homeostasis GO:0045454 63 46 0,000 0,08576363 0,09702722 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,08576363 0,09697952 ! regulation of ossification GO:0030278 71 46 0,000 0,08576363 0,09693186 ! histone modification GO:0016570 68 46 0,000 0,08576363 0,09688425 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,08576363 0,09683669 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08754638 0,09880111 ! viral infectious cycle GO:0019058 71 47 0,000 0,08754638 0,09875266 ! endocrine system development GO:0035270 83 47 0,000 0,08754638 0,09870425 ! covalent chromatin modification GO:0016569 75 47 0,000 0,08754638 0,09865589 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08754638 0,09860757 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08754638 0,09855931 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,08754638 0,09851109 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08754638 0,09846292 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,08754638 0,09841479 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,08754638 0,09836671 ! chloride transport GO:0006821 67 48 0,000 0,08932575 0,10031701 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,08932575 0,10026805 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,08932575 0,10021914 ! response to temperature stimulus GO:0009266 62 48 0,000 0,08932575 0,10017027 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,08932575 0,10012146 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,08932575 0,10007269 ! gastrulation GO:0007369 73 48 0,000 0,08932575 0,10002397 ! heart morphogenesis GO:0003007 65 48 0,000 0,08932575 0,09997529 ! regulation of DNA replication GO:0006275 75 48 0,000 0,08932575 0,09992667 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,08932575 0,09987809 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,08932575 0,09982956 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,08932575 0,09978107 ! regulation of endocytosis GO:0030100 63 48 0,000 0,08932575 0,09973264 ! nuclear export GO:0051168 69 48 0,000 0,08932575 0,09968425 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,08932575 0,0996359 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,08932575 0,09958761 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,09110176 0,10151843 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,09110176 0,10146927 ! sensory perception of smell GO:0007608 61 49 0,000 0,09110176 0,10142016 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,09110176 0,10137109 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,09110176 0,10132207 ! RNA elongation GO:0006354 62 49 0,000 0,09110176 0,1012731 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,09110176 0,10122418 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,09110176 0,1011753 ! germ cell development GO:0007281 68 49 0,000 0,09110176 0,10112647 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,09110176 0,10107769 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,09110176 0,10102895 ! maintenance of location GO:0051235 84 49 0,000 0,09110176 0,10098026 ! regulation of actin filament length GO:0030832 72 50 0,000 0,09287441 0,10289554 ! ear development GO:0043583 72 50 0,000 0,09287441 0,102846 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,09287441 0,1027965 ! membrane fusion GO:0006944 80 50 0,000 0,09287441 0,10274706 ! lipid modification GO:0030258 73 50 0,000 0,09287441 0,10269766 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09287441 0,10264831 ! proton transport GO:0015992 75 50 0,000 0,09287441 0,10259901 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09287441 0,10254975 ! positive regulation of secretion GO:0051047 71 51 0,000 0,0946437 0,10445322 ! hydrogen transport GO:0006818 77 51 0,000 0,0946437 0,10440312 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,0946437 0,10435307 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,0946437 0,10430307 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,0946437 0,10425311 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,0946437 0,10420321 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,0946437 0,10415335 ! adult behavior GO:0030534 80 51 0,000 0,0946437 0,10410354 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,0946437 0,10405378 ! transition metal ion transport GO:0000041 74 52 0,000 0,09640964 0,10594466 ! regulation of cellular component size GO:0032535 74 52 0,000 0,09640964 0,10589406 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,09640964 0,10584352 ! aging GO:0007568 79 52 0,000 0,09640964 0,10579302 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09640964 0,10574257 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09640964 0,10569217 ! establishment of organelle localization GO:0051656 85 52 0,000 0,09640964 0,10564181 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,09817224 0,10752197 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,09817224 0,1074708 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,09817224 0,10741967 ! kidney development GO:0001822 90 53 0,000 0,09817224 0,10736859 ! single fertilization GO:0007338 59 53 0,000 0,09817224 0,10731756 ! cell projection assembly GO:0030031 76 53 0,000 0,09817224 0,10726658 ! amino acid transport GO:0006865 84 54 0,000 0,0999315 0,10913696 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,0999315 0,10908516 ! regulation of mitosis GO:0007088 84 54 0,000 0,0999315 0,10903342 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,0999315 0,10898172 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,0999315 0,10893007 ! DNA catabolic process GO:0006308 67 54 0,000 0,0999315 0,10887846 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,0999315 0,10882691 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,0999315 0,10877541 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,0999315 0,10872395 ! exocytosis GO:0006887 74 55 0,000 0,10168742 0,11058207 ! mesoderm development GO:0007498 76 55 0,000 0,10168742 0,11052981 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,10168742 0,1104776 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,10168742 0,11042544 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10344003 0,11227563 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,10344003 0,11222267 ! carbohydrate transport GO:0008643 74 57 0,000 0,10518931 0,11406668 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,10518931 0,11401292 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,10518931 0,11395922 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,10518931 0,11390556 ! camera-type eye development GO:0043010 88 57 0,000 0,10518931 0,11385196 ! secondary metabolic process GO:0019748 84 57 0,000 0,10518931 0,11379841 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,10518931 0,11374491 ! developmental maturation GO:0021700 75 57 0,000 0,10518931 0,11369146 ! gonad development GO:0008406 79 57 0,000 0,10518931 0,11363806 ! viral reproductive process GO:0022415 87 58 0,000 0,10693529 0,11547003 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10693529 0,11541584 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10693529 0,11536171 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,10867795 0,11718673 ! activation of MAPK activity GO:0000187 84 59 0,000 0,10867795 0,11713181 ! lung development GO:0030324 94 59 0,000 0,10867795 0,11707695 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,10867795 0,11702214 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,10867795 0,11696738 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,11041732 0,11878383 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,11041732 0,1187283 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,11041732 0,11867282 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,11041732 0,11861739 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,11041732 0,11856201 ! regulation of heart contraction GO:0008016 91 60 0,000 0,11041732 0,11850668 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,11041732 0,11845141 ! fertilization GO:0009566 68 60 0,000 0,11041732 0,11839619 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,11041732 0,11834102 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,11215338 0,12014568 ! urogenital system development GO:0001655 101 61 0,000 0,11215338 0,12008975 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,11215338 0,12003387 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,11215338 0,11997804 ! extracellular matrix organization GO:0030198 103 61 0,000 0,11215338 0,11992226 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,11215338 0,11986654 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,11388617 0,12166195 ! neurotransmitter transport GO:0006836 81 62 0,000 0,11388617 0,12160547 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,11388617 0,12154904 ! respiratory tube development GO:0030323 99 62 0,000 0,11388617 0,12149266 ! organelle localization GO:0051640 96 62 0,000 0,11388617 0,12143634 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,11561567 0,12322337 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,11561567 0,12316629 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,11561567 0,12310927 ! viral reproduction GO:0016032 92 63 0,000 0,11561567 0,1230523 ! regulation of lipase activity GO:0060191 109 63 0,000 0,11561567 0,12299539 ! appendage morphogenesis GO:0035107 93 64 0,000 0,11734189 0,12477408 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,11734189 0,12471642 ! hexose catabolic process GO:0019320 82 64 0,000 0,11734189 0,12465882 ! respiratory system development GO:0060541 100 64 0,000 0,11734189 0,12460127 ! adaptive immune response GO:0002250 94 64 0,000 0,11734189 0,12454377 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,11906484 0,12631417 ! appendage development GO:0048736 94 65 0,000 0,11906484 0,12625594 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,11906484 0,12619776 ! defense response to bacterium GO:0042742 73 65 0,000 0,11906484 0,12613963 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,11906484 0,12608155 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,11906484 0,12602353 ! activation of immune response GO:0002253 83 65 0,000 0,11906484 0,12596556 ! protein oligomerization GO:0051259 100 65 0,000 0,11906484 0,12590765 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,12078453 0,12766747 ! antigen processing and presentation GO:0019882 96 66 0,000 0,12078453 0,12760882 ! axon guidance GO:0007411 99 66 0,000 0,12078453 0,12755024 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,12078453 0,1274917 ! regulation of immune effector process GO:0002697 101 66 0,000 0,12078453 0,12743322 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,12250096 0,12918487 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,12250096 0,12912566 ! acute inflammatory response GO:0002526 92 68 0,000 0,12421413 0,13087151 ! learning or memory GO:0007611 123 68 0,000 0,12421413 0,13081159 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,12421413 0,13075172 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,12421413 0,1306919 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,12421413 0,13063215 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,12421413 0,13057244 ! rhythmic process GO:0048511 105 68 0,000 0,12421413 0,13051279 ! inorganic anion transport GO:0015698 93 68 0,000 0,12421413 0,1304532 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,12592406 0,13218865 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,12592406 0,13212835 ! response to drug GO:0042493 108 69 0,000 0,12592406 0,1320681 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,12763075 0,13379705 ! humoral immune response GO:0006959 86 70 0,000 0,12763075 0,1337361 ! amine transport GO:0015837 101 70 0,000 0,12763075 0,1336752 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,12763075 0,13361435 ! regulation of catabolic process GO:0009894 106 70 0,000 0,12763075 0,13355356 ! muscle cell differentiation GO:0042692 104 71 0,000 0,12933421 0,13527452 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,12933421 0,13521303 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,12933421 0,1351516 ! response to hypoxia GO:0001666 132 72 0,000 0,13103443 0,13686612 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,13103443 0,13680399 ! negative regulation of transport GO:0051051 116 73 0,000 0,13273144 0,13851284 ! regulation of blood pressure GO:0008217 107 73 0,000 0,13273144 0,13845002 ! tube morphogenesis GO:0035239 118 73 0,000 0,13273144 0,13838726 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,13273144 0,13832456 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,13442522 0,14002627 ! response to oxygen levels GO:0070482 137 74 0,000 0,13442522 0,13996288 ! digestion GO:0007586 97 74 0,000 0,13442522 0,13989955 ! protein import into nucleus GO:0006606 118 74 0,000 0,13442522 0,13983628 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,13442522 0,13977306 ! blood coagulation GO:0007596 116 75 0,000 0,1361158 0,14146694 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,1361158 0,14140304 ! nuclear import GO:0051170 121 75 0,000 0,1361158 0,1413392 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,1361158 0,14127542 ! amine biosynthetic process GO:0009309 97 76 0,000 0,13780317 0,14296224 ! tRNA metabolic process GO:0006399 95 76 0,000 0,13780317 0,14289779 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,13780317 0,14283339 ! regulation of protein transport GO:0051223 114 76 0,000 0,13780317 0,14276905 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,13948734 0,14444884 ! regulation of DNA binding GO:0051101 119 77 0,000 0,13948734 0,14438384 ! gland development GO:0048732 148 77 0,000 0,13948734 0,14431889 ! sex differentiation GO:0007548 105 77 0,000 0,13948734 0,14425399 ! protein ubiquitination GO:0016567 125 77 0,000 0,13948734 0,14418916 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,13948734 0,14412439 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,13948734 0,14405967 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,14116832 0,14573031 ! cellular respiration GO:0045333 107 79 0,000 0,14284611 0,14739617 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,14284611 0,14733007 ! T cell activation GO:0042110 134 79 0,000 0,14284611 0,14726403 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,14284611 0,14719805 ! chromatin assembly GO:0031497 102 80 0,000 0,14452072 0,14885699 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,14452072 0,14879036 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,14452072 0,14872378 ! forebrain development GO:0030900 131 80 0,000 0,14452072 0,14865727 ! hemostasis GO:0007599 125 81 0,000 0,14619215 0,15030932 ! mRNA transport GO:0051028 121 81 0,000 0,14619215 0,15024216 ! regulation of neurological system process GO:0031644 122 81 0,000 0,14619215 0,15017506 ! vitamin metabolic process GO:0006766 103 81 0,000 0,14619215 0,15010802 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,14952552 0,15346216 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,14952552 0,15339371 ! regulation of defense response GO:0031347 117 84 0,000 0,15118746 0,1550295 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,15118746 0,15496041 ! sterol metabolic process GO:0016125 120 84 0,000 0,15118746 0,15489139 ! rRNA metabolic process GO:0016072 107 85 0,000 0,15284625 0,15652109 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,15284625 0,15645144 ! transcription initiation GO:0006352 118 85 0,000 0,15284625 0,15638184 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,15284625 0,15631231 ! regulation of protein localization GO:0032880 132 85 0,000 0,15284625 0,15624283 ! regulation of membrane potential GO:0042391 128 85 0,000 0,15284625 0,15617342 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,15284625 0,15610407 ! nucleosome organization GO:0034728 114 87 0,000 0,1561544 0,15941195 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,1561544 0,15934122 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,1561544 0,15927056 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,1561544 0,15919996 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,1561544 0,15912943 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,15780376 0,160739 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,15780376 0,16066784 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,15780376 0,16059675 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,15780376 0,16052572 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,15780376 0,16045476 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,15945 0,16205701 ! reproductive developmental process GO:0003006 127 89 0,000 0,15945 0,16198543 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,15945 0,16191391 ! regulation of T cell activation GO:0050863 128 89 0,000 0,15945 0,16184246 ! leukocyte differentiation GO:0002521 143 90 0,000 0,16109312 0,1634381 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,16109312 0,16336604 ! hormone metabolic process GO:0042445 121 90 0,000 0,16109312 0,16329404 ! RNA localization GO:0006403 135 91 0,000 0,16273312 0,16488377 ! ATP metabolic process GO:0046034 137 91 0,000 0,16273312 0,16481117 ! response to virus GO:0009615 122 91 0,000 0,16273312 0,16473863 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,16437 0,16632248 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,16437 0,16624934 ! cell fate commitment GO:0045165 141 92 0,000 0,16437 0,16617626 ! positive regulation of immune response GO:0050778 121 92 0,000 0,16437 0,16610325 ! sulfur metabolic process GO:0006790 118 92 0,000 0,16437 0,1660303 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,16600378 0,16760698 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,16600378 0,16753343 ! electron transport chain GO:0022900 123 94 0,000 0,16763446 0,16910494 ! response to oxidative stress GO:0006979 141 94 0,000 0,16763446 0,1690308 ! regulation of binding GO:0051098 151 95 0,000 0,16926204 0,17059715 ! angiogenesis GO:0001525 149 95 0,000 0,16926204 0,17052243 ! carboxylic acid transport GO:0046942 147 95 0,000 0,16926204 0,17044777 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,17088654 0,17200833 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,17088654 0,17193309 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,17088654 0,17185791 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,17088654 0,1717828 ! protein maturation GO:0051604 129 96 0,000 0,17088654 0,17170775 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,17250795 0,17326126 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,17250795 0,17318563 ! extracellular structure organization GO:0043062 156 99 0,000 0,17574154 0,17635495 ! protein import GO:0017038 156 99 0,000 0,17574154 0,17627804 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,17574154 0,1762012 ! regulation of translation GO:0006417 151 100 0,000 0,17735374 0,17774013 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,17735374 0,17766272 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,17735374 0,17758537 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,17735374 0,17750809 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,17735374 0,17743088 ! protein localization in organelle GO:0033365 161 100 0,000 0,17735374 0,17735374