pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5599-7-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 1,332E-11 3,205E-08 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 5,568E-10 6,698E-07 GO:0042267|natural killer cell mediated cytotoxicity, ! spindle organization GO:0007051 46 32 4,000 6,254E-10 5,016E-07 ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 1,31E-09 7,879E-07 ! cell killing GO:0001906 29 15 3,000 3,602E-09 1,733E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,269E-08 5,089E-06 ! polyol catabolic process GO:0046174 7 5 2,000 2,166E-08 7,446E-06 GO:0019405|alditol catabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 3,306E-08 9,943E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,693E-07 4,525E-05 ! interphase GO:0051325 213 98 4,000 1,978E-07 4,76E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,82E-07 8,356E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 4,18E-07 8,381E-05 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 6,15E-07 1,138E-04 ! response to UV GO:0009411 104 53 3,000 7,451E-07 1,28E-04 ! fructose metabolic process GO:0006000 25 16 2,000 1,201E-06 1,926E-04 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 1,6E-06 2,406E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,436E-06 3,447E-04 ! leukocyte mediated immunity GO:0002443 128 74 3,000 2,87E-06 3,836E-04 ! alditol metabolic process GO:0019400 38 24 2,000 4,308E-06 5,456E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 4,891E-06 5,884E-04 ! sperm motility GO:0030317 31 25 2,000 4,891E-06 5,604E-04 ! osteoblast differentiation GO:0001649 60 25 2,000 4,891E-06 5,349E-04 ! hexose biosynthetic process GO:0019319 48 32 2,000 1,048E-05 1,096E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 1,503E-05 1,507E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,503E-05 1,447E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,716E-05 1,588E-03 ! polyol metabolic process GO:0019751 66 41 2,000 2,234E-05 1,991E-03 ! alcohol biosynthetic process GO:0046165 59 42 2,000 2,404E-05 2,065E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 2,571E-05 2,133E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,571E-05 2,062E-03 GO:0046530|photoreceptor cell differentiation, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,571E-05 1,996E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 3,597E-05 2,704E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 3,597E-05 2,622E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 3,597E-05 2,545E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,792E-05 3,294E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 4,792E-05 3,202E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 6,155E-05 4,003E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 6,155E-05 3,897E-03 ! postreplication repair GO:0006301 22 9 1,000 6,155E-05 3,797E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 6,155E-05 3,703E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 7,047E-05 4,135E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,688E-05 4,404E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 7,688E-05 4,302E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,688E-05 4,204E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 7,688E-05 4,11E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 7,688E-05 4,021E-03 ! Golgi vesicle budding GO:0048194 22 11 1,000 9,388E-05 4,806E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,388E-05 4,706E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 9,802E-05 4,813E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,024E-04 4,93E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 1,024E-04 4,833E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 1,07E-04 4,951E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,126E-04 5,11E-03 ! cartilage condensation GO:0001502 20 12 1,000 1,126E-04 5,015E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,126E-04 4,924E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 1,215E-04 5,219E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 1,215E-04 5,127E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,215E-04 5,039E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,329E-04 5,42E-03 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 1,329E-04 5,33E-03 ! regulation of DNA repair GO:0006282 21 13 1,000 1,329E-04 5,243E-03 ! positive regulation of ligase activity GO:0051351 124 77 2,000 1,483E-04 5,755E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,549E-04 5,917E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,549E-04 5,825E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 1,6E-04 5,923E-03 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,661E-04 6,055E-03 ! positive regulation of cell size GO:0045793 27 15 1,000 1,786E-04 6,415E-03 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 1,787E-04 6,323E-03 ! regulation of cyclase activity GO:0031279 159 82 2,000 1,787E-04 6,232E-03 ! regulation of lyase activity GO:0051339 160 83 2,000 1,852E-04 6,367E-03 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 1,919E-04 6,504E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 1,919E-04 6,414E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 2,04E-04 6,723E-03 ! alcohol catabolic process GO:0046164 130 86 2,000 2,058E-04 6,69E-03 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 2,129E-04 6,831E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 2,000 2,202E-04 6,972E-03 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,31E-04 7,217E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,31E-04 7,125E-03 ! membrane budding GO:0006900 37 17 1,000 2,31E-04 7,035E-03 ! ossification GO:0001503 188 90 2,000 2,353E-04 7,078E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 2,353E-04 6,991E-03 ! bone development GO:0060348 189 91 2,000 2,431E-04 7,134E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 2,592E-04 7,515E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 2,592E-04 7,425E-03 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 2,592E-04 7,338E-03 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,596E-04 7,264E-03 ! centrosome cycle GO:0007098 25 18 1,000 2,596E-04 7,18E-03 ! skin development GO:0043588 36 19 1,000 2,899E-04 7,927E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,899E-04 7,838E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 35 19 1,000 2,899E-04 7,751E-03 ! Golgi vesicle transport GO:0048193 207 99 2,000 3,116E-04 8,239E-03 ! cell cycle arrest GO:0007050 213 100 2,000 3,21E-04 8,394E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,219E-04 8,327E-03 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,219E-04 8,239E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 3,555E-04 9,003E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,907E-04 9,791E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,907E-04 9,691E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,275E-04 0,01049631 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,66E-04 0,01132534 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 4,66E-04 0,01121208 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,66E-04 0,01110107 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,061E-04 0,01193805 ! microtubule organizing center organization GO:0031023 39 26 1,000 5,478E-04 0,01279657 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,478E-04 0,01267353 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 5,478E-04 0,01255283 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,911E-04 0,01341788 ! fat cell differentiation GO:0045444 50 27 1,000 5,911E-04 0,01329248 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,361E-04 0,01417053 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,826E-04 0,0150679 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 6,826E-04 0,01493092 ! eye morphogenesis GO:0048592 60 30 1,000 7,308E-04 0,01583999 ! regulation of B cell activation GO:0050864 50 30 1,000 7,308E-04 0,01569856 ! response to mechanical stimulus GO:0009612 57 32 1,000 8,319E-04 0,01771179 ! protein targeting to membrane GO:0006612 68 33 1,000 8,848E-04 0,01867342 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 9,954E-04 0,02082499 ! regulation of microtubule-based process GO:0032886 78 35 1,000 9,954E-04 0,02064546 ! cell junction organization GO:0034330 86 36 1,000 1,053E-03 0,02165488 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 1,053E-03 0,02147136 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 1,053E-03 0,02129093 ! meiosis I GO:0007127 65 37 1,000 1,112E-03 0,02230127 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 1,112E-03 0,02211696 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 1,173E-03 0,0231349 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,173E-03 0,02294681 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! keratinocyte differentiation GO:0030216 62 41 1,000 1,365E-03 0,02648324 ! double-strand break repair GO:0006302 81 44 1,000 1,571E-03 0,03023202 ! JAK-STAT cascade GO:0007259 71 44 1,000 1,571E-03 0,02999208 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,716E-03 0,03250081 ! response to calcium ion GO:0051592 81 47 1,000 1,79E-03 0,03365186 ! JNK cascade GO:0007254 91 47 1,000 1,79E-03 0,03339099 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,867E-03 0,03454578 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,867E-03 0,03428207 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 1,944E-03 0,03544039 ! detection of abiotic stimulus GO:0009582 74 49 1,000 1,944E-03 0,03517392 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 2,024E-03 0,03633559 ! response to estrogen stimulus GO:0043627 93 51 1,000 2,105E-03 0,03750709 ! vesicle organization GO:0016050 107 51 1,000 2,105E-03 0,0372313 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,105E-03 0,03695954 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 2,187E-03 0,03812741 ! cartilage development GO:0051216 90 52 1,000 2,187E-03 0,03785311 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 2,356E-03 0,04049081 ! skeletal system morphogenesis GO:0048705 105 59 1,000 2,805E-03 0,04786922 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 2,805E-03 0,04753211 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 3,191E-03 0,05369534 ! detection of external stimulus GO:0009581 91 63 1,000 3,191E-03 0,05332246 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 3,191E-03 0,05295472 ! actin filament organization GO:0007015 148 66 1,000 3,496E-03 0,05761743 ! regulation of cellular response to stress GO:0080135 128 67 1,000 3,601E-03 0,0589369 ! negative regulation of cell growth GO:0030308 132 67 1,000 3,601E-03 0,05853868 ! chromosome segregation GO:0007059 113 67 1,000 3,601E-03 0,0581458 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 3,707E-03 0,05945861 ! cell cycle checkpoint GO:0000075 137 69 1,000 3,814E-03 0,06077708 ! negative regulation of cell size GO:0045792 134 69 1,000 3,814E-03 0,06037723 ! regulation of caspase activity GO:0043281 122 72 1,000 4,145E-03 0,06518802 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 4,145E-03 0,06476472 ! meiosis GO:0007126 121 74 1,000 4,373E-03 0,06788354 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 4,373E-03 0,06744839 ! eye development GO:0001654 143 74 1,000 4,373E-03 0,06701878 ! cell-matrix adhesion GO:0007160 163 75 1,000 4,489E-03 0,0683619 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 4,489E-03 0,06793196 ! meiotic cell cycle GO:0051321 122 75 1,000 4,489E-03 0,06750738 ! steroid biosynthetic process GO:0006694 131 76 1,000 4,607E-03 0,06884366 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 4,726E-03 0,07018446 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 4,726E-03 0,06975388 ! negative regulation of organelle organization GO:0010639 161 78 1,000 4,846E-03 0,0710935 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 4,846E-03 0,07066263 ! regulation of peptidase activity GO:0052547 134 79 1,000 4,968E-03 0,07200104 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,968E-03 0,0715699 ! response to metal ion GO:0010038 140 80 1,000 5,091E-03 0,07290709 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 5,215E-03 0,0742484 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 5,215E-03 0,07381165 ! negative regulation of growth GO:0045926 155 84 1,000 5,597E-03 0,07875366 ! response to unfolded protein GO:0006986 131 85 1,000 5,727E-03 0,08011544 ! positive regulation of cell activation GO:0050867 145 85 1,000 5,727E-03 0,07965234 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 5,859E-03 0,08101241 ! mitochondrion organization GO:0007005 148 86 1,000 5,859E-03 0,08054948 ! regulation of cell cycle process GO:0010564 149 90 1,000 6,398E-03 0,08746846 ! response to protein stimulus GO:0051789 149 91 1,000 6,537E-03 0,0888545 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,624E-03 0,0895301 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,624E-03 0,08902993 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,624E-03 0,08853532 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,624E-03 0,08804617 ! neuron fate determination GO:0048664 7 5 0,000 6,624E-03 0,0875624 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,624E-03 0,08708392 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,624E-03 0,08661064 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,624E-03 0,08614247 ! polyol transport GO:0015791 12 5 0,000 6,624E-03 0,08567934 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,624E-03 0,08522116 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,624E-03 0,08476786 ! response to superoxide GO:0000303 10 5 0,000 6,624E-03 0,08431935 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,624E-03 0,08387556 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,624E-03 0,08343643 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,624E-03 0,08300186 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,624E-03 0,0825718 ! female meiosis GO:0007143 7 5 0,000 6,624E-03 0,08214617 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,624E-03 0,08172491 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,624E-03 0,08130795 ! cobalt ion transport GO:0006824 11 5 0,000 6,624E-03 0,08089521 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,624E-03 0,08048665 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,624E-03 0,0800822 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,624E-03 0,07968179 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,624E-03 0,07928536 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,624E-03 0,07889286 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,624E-03 0,07850422 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,624E-03 0,0781194 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,624E-03 0,07773833 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,624E-03 0,07736096 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,624E-03 0,07698723 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,624E-03 0,0766171 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,624E-03 0,07625051 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,624E-03 0,07588742 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,624E-03 0,07552776 ! negative chemotaxis GO:0050919 14 5 0,000 6,624E-03 0,0751715 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,624E-03 0,07481858 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,624E-03 0,07446896 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,624E-03 0,07412259 ! behavioral response to pain GO:0048266 9 5 0,000 6,624E-03 0,07377943 ! clathrin coat assembly GO:0048268 14 5 0,000 6,624E-03 0,07343943 ! Notch receptor processing GO:0007220 8 5 0,000 6,624E-03 0,07310256 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,624E-03 0,07276875 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,624E-03 0,07243799 ! micturition GO:0060073 9 5 0,000 6,624E-03 0,07211021 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,624E-03 0,07178539 ! copulation GO:0007620 9 5 0,000 6,624E-03 0,07146349 ! glial cell fate commitment GO:0021781 13 5 0,000 6,624E-03 0,07114445 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,624E-03 0,07082825 ! spermidine metabolic process GO:0008216 7 5 0,000 6,624E-03 0,07051485 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,624E-03 0,07020422 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,624E-03 0,0698963 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,624E-03 0,06959108 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,624E-03 0,06928851 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,624E-03 0,06898856 ! grooming behavior GO:0007625 6 5 0,000 6,624E-03 0,06869119 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,624E-03 0,06839638 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,624E-03 0,06810409 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,624E-03 0,06781429 ! response to protozoan GO:0001562 10 5 0,000 6,624E-03 0,06752694 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,624E-03 0,06724201 ! lymph vessel development GO:0001945 10 5 0,000 6,624E-03 0,06695948 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,624E-03 0,06667932 ! endochondral ossification GO:0001958 16 5 0,000 6,624E-03 0,06640149 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,624E-03 0,06612596 ! parathyroid gland development GO:0060017 13 5 0,000 6,624E-03 0,06585272 ! anagen GO:0042640 6 5 0,000 6,624E-03 0,06558172 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,624E-03 0,06531294 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,624E-03 0,06504636 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,624E-03 0,06478194 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,624E-03 0,06451966 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,624E-03 0,0642595 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,624E-03 0,06400143 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,624E-03 0,06374543 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,624E-03 0,06349146 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,624E-03 0,06323951 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,624E-03 0,06298955 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,624E-03 0,06274156 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,624E-03 0,06249552 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,624E-03 0,0622514 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,624E-03 0,06200917 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,624E-03 0,06176883 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,624E-03 0,06153034 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,624E-03 0,06129368 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,624E-03 0,06105884 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,624E-03 0,06082579 ! histidine catabolic process GO:0006548 6 5 0,000 6,624E-03 0,06059451 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,624E-03 0,06036499 ! microvillus organization GO:0032528 7 5 0,000 6,624E-03 0,0601372 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,624E-03 0,05991112 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,624E-03 0,05968673 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,624E-03 0,05946402 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,624E-03 0,05924296 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,624E-03 0,05902355 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,624E-03 0,05880575 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,624E-03 0,05858955 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,624E-03 0,05837493 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,624E-03 0,05816189 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,624E-03 0,05795039 ! muscle cell migration GO:0014812 8 5 0,000 6,624E-03 0,05774042 ! mitochondrial fission GO:0000266 8 5 0,000 6,624E-03 0,05753198 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,624E-03 0,05732503 ! mRNA transcription GO:0009299 9 5 0,000 6,624E-03 0,05711956 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,624E-03 0,05691556 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,624E-03 0,05671302 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,624E-03 0,05651191 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,624E-03 0,05631222 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,624E-03 0,05611393 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,624E-03 0,05591704 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,624E-03 0,05572153 ! response to food GO:0032094 6 5 0,000 6,624E-03 0,05552738 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,624E-03 0,05533457 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,624E-03 0,0551431 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,624E-03 0,05495296 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,624E-03 0,05476411 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,624E-03 0,05457657 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,624E-03 0,0543903 ! forebrain neuron development GO:0021884 13 5 0,000 6,624E-03 0,0542053 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,624E-03 0,05402155 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,624E-03 0,05383904 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,624E-03 0,05365777 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,624E-03 0,05347771 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,624E-03 0,05329885 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,624E-03 0,05312119 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,624E-03 0,05294471 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,624E-03 0,05276939 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,624E-03 0,05259524 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,624E-03 0,05242223 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,624E-03 0,05225035 ! basic amino acid transport GO:0015802 11 5 0,000 6,624E-03 0,0520796 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,624E-03 0,05190996 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,624E-03 0,05174142 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,624E-03 0,05157397 ! depyrimidination GO:0045008 10 5 0,000 6,624E-03 0,0514076 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,624E-03 0,05124231 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,624E-03 0,05107807 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,624E-03 0,05091488 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,624E-03 0,05075273 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,624E-03 0,05059161 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,624E-03 0,05043151 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,624E-03 0,05027242 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,624E-03 0,05011433 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,624E-03 0,04995723 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,624E-03 0,04980112 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,624E-03 0,04964597 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,624E-03 0,04949179 ! response to arsenic GO:0046685 10 5 0,000 6,624E-03 0,04933857 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,624E-03 0,04918629 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,624E-03 0,04903495 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,624E-03 0,04888453 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,624E-03 0,04873504 ! response to cadmium ion GO:0046686 7 5 0,000 6,624E-03 0,04858645 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,624E-03 0,04843878 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,624E-03 0,04829199 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,624E-03 0,04814609 ! decidualization GO:0046697 11 5 0,000 6,624E-03 0,04800108 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,624E-03 0,04785693 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,624E-03 0,04771364 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,624E-03 0,04757122 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,624E-03 0,04742963 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,624E-03 0,04728889 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,624E-03 0,04714899 ! neural tube patterning GO:0021532 7 5 0,000 6,624E-03 0,0470099 ! embryonic cleavage GO:0040016 6 5 0,000 6,624E-03 0,04687164 ! peroxisome fission GO:0016559 5 5 0,000 6,624E-03 0,04673419 ! histone demethylation GO:0016577 10 5 0,000 6,624E-03 0,04659754 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,624E-03 0,04646168 ! mitotic recombination GO:0006312 9 5 0,000 6,624E-03 0,04632662 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,624E-03 0,04619234 ! metaphase plate congression GO:0051310 7 5 0,000 6,624E-03 0,04605884 ! regulation of sterol transport GO:0032371 7 5 0,000 6,624E-03 0,0459261 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,624E-03 0,04579413 ! enteric nervous system development GO:0048484 8 5 0,000 6,624E-03 0,04566291 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,624E-03 0,04553245 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,624E-03 0,04540273 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,624E-03 0,04527374 ! muscle cell proliferation GO:0033002 11 5 0,000 6,624E-03 0,04514549 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,624E-03 0,04501796 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,624E-03 0,04489115 ! plasminogen activation GO:0031639 5 5 0,000 6,624E-03 0,04476505 ! B cell homeostasis GO:0001782 13 5 0,000 6,624E-03 0,04463966 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,624E-03 0,04451496 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,624E-03 0,04439097 ! metaphase GO:0051323 8 5 0,000 6,624E-03 0,04426766 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,624E-03 0,04414503 ! cellular response to nutrient GO:0031670 8 5 0,000 6,624E-03 0,04402309 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,624E-03 0,04390181 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,624E-03 0,0437812 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,624E-03 0,04366125 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,624E-03 0,04354196 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,624E-03 0,04342332 ! response to redox state GO:0051775 5 5 0,000 6,624E-03 0,04330532 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,624E-03 0,04318796 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,624E-03 0,04307124 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,624E-03 0,04295514 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,624E-03 0,04283967 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,624E-03 0,04272482 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,624E-03 0,04261058 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,624E-03 0,04249695 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,624E-03 0,04238393 ! striatum development GO:0021756 9 5 0,000 6,624E-03 0,0422715 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,624E-03 0,04215968 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,624E-03 0,04204844 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,624E-03 0,04193778 ! glial cell migration GO:0008347 11 5 0,000 6,624E-03 0,04182771 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,624E-03 0,04171821 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,624E-03 0,04160929 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,624E-03 0,04150093 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,624E-03 0,04139314 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,624E-03 0,0412859 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,624E-03 0,04117922 ! neuroprotection GO:0043526 6 5 0,000 6,624E-03 0,04107309 ! neural plate development GO:0001840 8 5 0,000 6,624E-03 0,0409675 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,624E-03 0,04086245 ! regulation of sensory perception GO:0051931 7 5 0,000 6,624E-03 0,04075795 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,624E-03 0,04065397 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,624E-03 0,04055053 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,624E-03 0,04044761 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,624E-03 0,04034521 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,624E-03 0,04024333 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,624E-03 0,04014196 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,624E-03 0,0400411 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,624E-03 0,03994074 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,624E-03 0,03984089 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,624E-03 0,03974154 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,624E-03 0,03964268 ! drug metabolic process GO:0017144 6 5 0,000 6,624E-03 0,03954431 ! stem cell division GO:0017145 11 5 0,000 6,624E-03 0,03944643 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,624E-03 0,03934903 ! organ regeneration GO:0031100 7 5 0,000 6,624E-03 0,03925211 ! carnitine metabolic process GO:0009437 7 5 0,000 6,624E-03 0,03915567 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,624E-03 0,0390597 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,624E-03 0,0389642 ! detection of stimulus GO:0051606 151 96 1,000 7,249E-03 0,04253691 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 7,395E-03 0,04329058 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,943E-03 0,04638654 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,943E-03 0,04627423 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,943E-03 0,04616245 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,943E-03 0,04605122 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,943E-03 0,04594052 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,943E-03 0,04583035 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,943E-03 0,04572071 ! sleep GO:0030431 13 6 0,000 7,943E-03 0,04561159 ! response to oxygen radical GO:0000305 11 6 0,000 7,943E-03 0,04550299 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,943E-03 0,04539491 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,943E-03 0,04528734 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,943E-03 0,04518027 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,943E-03 0,04507372 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,943E-03 0,04496766 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,943E-03 0,0448621 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,943E-03 0,04475704 ! forebrain regionalization GO:0021871 8 6 0,000 7,943E-03 0,04465247 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,943E-03 0,04454838 ! male meiosis GO:0007140 7 6 0,000 7,943E-03 0,04444478 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,943E-03 0,04434166 ! response to zinc ion GO:0010043 9 6 0,000 7,943E-03 0,04423902 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,943E-03 0,04413685 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,943E-03 0,04403515 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,943E-03 0,04393392 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,943E-03 0,04383316 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,943E-03 0,04373285 ! malate metabolic process GO:0006108 11 6 0,000 7,943E-03 0,043633 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,943E-03 0,04353361 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,943E-03 0,04343467 ! protein refolding GO:0042026 15 6 0,000 7,943E-03 0,04333618 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,943E-03 0,04323814 ! opsonization GO:0008228 8 6 0,000 7,943E-03 0,04314053 ! mating behavior GO:0007617 7 6 0,000 7,943E-03 0,04304337 ! neuron remodeling GO:0016322 15 6 0,000 7,943E-03 0,04294664 ! erythrocyte maturation GO:0043249 7 6 0,000 7,943E-03 0,04285035 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,943E-03 0,04275449 ! equilibrioception GO:0050957 14 6 0,000 7,943E-03 0,04265905 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,943E-03 0,04256404 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,943E-03 0,04246946 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,943E-03 0,04237529 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,943E-03 0,04228154 ! response to interferon-gamma GO:0034341 15 6 0,000 7,943E-03 0,0421882 ! toxin metabolic process GO:0009404 11 6 0,000 7,943E-03 0,04209528 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,943E-03 0,04200276 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,943E-03 0,04191065 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,943E-03 0,04181894 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,943E-03 0,04172763 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 7,943E-03 0,04163672 ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,943E-03 0,04154621 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,943E-03 0,04145609 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,943E-03 0,04136635 ! thymic T cell selection GO:0045061 12 6 0,000 7,943E-03 0,04127701 ! protein lipoylation GO:0009249 10 6 0,000 7,943E-03 0,04118805 ! cysteine metabolic process GO:0006534 10 6 0,000 7,943E-03 0,04109947 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,943E-03 0,04101128 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,943E-03 0,04092346 ! glutamate catabolic process GO:0006538 10 6 0,000 7,943E-03 0,04083602 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 7,943E-03 0,04074895 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,943E-03 0,04066225 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,943E-03 0,04057591 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,943E-03 0,04048995 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,943E-03 0,04040435 ! hyperosmotic response GO:0006972 9 6 0,000 7,943E-03 0,04031911 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,943E-03 0,04023422 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,943E-03 0,0401497 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,943E-03 0,04006553 ! urea metabolic process GO:0019627 7 6 0,000 7,943E-03 0,03998171 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,943E-03 0,03989824 ! neutrophil activation GO:0042119 8 6 0,000 7,943E-03 0,03981512 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,943E-03 0,03973234 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,943E-03 0,03964991 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,943E-03 0,03956782 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,943E-03 0,03948607 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,943E-03 0,03940465 ! neuron apoptosis GO:0051402 9 6 0,000 7,943E-03 0,03932357 ! nucleoside salvage GO:0043174 9 6 0,000 7,943E-03 0,03924283 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,943E-03 0,03916241 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,943E-03 0,03908232 ! T cell mediated immunity GO:0002456 16 6 0,000 7,943E-03 0,03900256 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,943E-03 0,03892313 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,943E-03 0,03884402 ! carnitine transport GO:0015879 10 6 0,000 7,943E-03 0,03876522 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,943E-03 0,03868675 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,943E-03 0,0386086 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,943E-03 0,03853076 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,943E-03 0,03845323 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,943E-03 0,03837602 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,943E-03 0,03829911 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,943E-03 0,03822251 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,943E-03 0,03814622 ! establishment of spindle localization GO:0051293 12 6 0,000 7,943E-03 0,03807023 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,943E-03 0,03799454 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,943E-03 0,03791916 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,943E-03 0,03784407 ! neural nucleus development GO:0048857 14 6 0,000 7,943E-03 0,03776928 ! response to UV-C GO:0010225 11 6 0,000 7,943E-03 0,03769478 ! astrocyte development GO:0014002 15 6 0,000 7,943E-03 0,03762058 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,943E-03 0,03754667 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,943E-03 0,03747305 ! interaction with symbiont GO:0051702 13 6 0,000 7,943E-03 0,03739972 ! regulation of dendrite development GO:0050773 16 6 0,000 7,943E-03 0,03732667 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,943E-03 0,03725391 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,943E-03 0,03718143 ! response to copper ion GO:0046688 10 6 0,000 7,943E-03 0,03710923 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,943E-03 0,03703732 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,943E-03 0,03696568 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,943E-03 0,03689432 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,943E-03 0,03682323 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,943E-03 0,03675241 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,943E-03 0,03668187 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,943E-03 0,0366116 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,943E-03 0,0365416 ! hair follicle maturation GO:0048820 7 6 0,000 7,943E-03 0,03647186 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,943E-03 0,03640239 ! Schwann cell development GO:0014044 15 6 0,000 7,943E-03 0,03633319 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,943E-03 0,03626424 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,943E-03 0,03619556 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,943E-03 0,03612714 ! subpallium development GO:0021544 10 6 0,000 7,943E-03 0,03605897 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,943E-03 0,03599107 ! histone ubiquitination GO:0016574 8 6 0,000 7,943E-03 0,03592341 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,943E-03 0,03585601 ! maintenance of organ identity GO:0048496 9 6 0,000 7,943E-03 0,03578887 ! G2 phase GO:0051319 16 6 0,000 7,943E-03 0,03572197 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,943E-03 0,03565533 ! establishment of planar polarity GO:0001736 7 6 0,000 7,943E-03 0,03558893 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,943E-03 0,03552278 ! membrane to membrane docking GO:0022614 14 6 0,000 7,943E-03 0,03545688 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,943E-03 0,03539121 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,943E-03 0,0353258 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,943E-03 0,03526062 ! receptor internalization GO:0031623 10 6 0,000 7,943E-03 0,03519568 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 7,943E-03 0,03513098 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 7,943E-03 0,03506652 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,943E-03 0,0350023 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,943E-03 0,03493831 ! protein deubiquitination GO:0016579 14 6 0,000 7,943E-03 0,03487455 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,943E-03 0,03481103 ! protein destabilization GO:0031648 9 6 0,000 7,943E-03 0,03474774 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,943E-03 0,03468467 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,943E-03 0,03462184 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,943E-03 0,03455923 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,943E-03 0,03449685 ! progesterone metabolic process GO:0042448 10 6 0,000 7,943E-03 0,0344347 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,943E-03 0,03437276 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,943E-03 0,03431105 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,943E-03 0,03424956 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,943E-03 0,03418829 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,943E-03 0,03412724 ! determination of adult lifespan GO:0008340 15 6 0,000 7,943E-03 0,03406641 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,943E-03 0,03400579 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,943E-03 0,03394539 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,943E-03 0,03388521 ! catecholamine transport GO:0051937 9 6 0,000 7,943E-03 0,03382523 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,943E-03 0,03376547 ! sensory cilium assembly GO:0035058 10 6 0,000 7,943E-03 0,03370592 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,943E-03 0,03364658 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,943E-03 0,03358744 ! maternal placenta development GO:0001893 12 6 0,000 7,943E-03 0,03352852 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,943E-03 0,0334698 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,943E-03 0,03341129 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,943E-03 0,03335298 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,943E-03 0,03329487 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,943E-03 0,03323697 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 7,943E-03 0,03317926 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,943E-03 0,03312176 ! tRNA transcription GO:0009304 14 7 0,000 9,261E-03 0,03855025 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,261E-03 0,03848367 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 9,261E-03 0,03841731 ! regulation of helicase activity GO:0051095 15 7 0,000 9,261E-03 0,03835119 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,261E-03 0,0382853 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,261E-03 0,03821963 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,261E-03 0,03815418 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,261E-03 0,03808896 ! prostate gland development GO:0030850 13 7 0,000 9,261E-03 0,03802396 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,261E-03 0,03795919 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,261E-03 0,03789463 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,261E-03 0,03783029 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,261E-03 0,03776617 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,261E-03 0,03770227 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,261E-03 0,03763858 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,261E-03 0,03757511 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 9,261E-03 0,03751186 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,261E-03 0,03744881 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,261E-03 0,03738598 ! glycolipid transport GO:0046836 10 7 0,000 9,261E-03 0,03732335 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,261E-03 0,03726094 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,261E-03 0,03719873 ! neuron adhesion GO:0007158 12 7 0,000 9,261E-03 0,03713674 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 9,261E-03 0,03707495 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,261E-03 0,03701336 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,261E-03 0,03695198 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 9,261E-03 0,0368908 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,261E-03 0,03682982 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,261E-03 0,03676905 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,261E-03 0,03670847 ! mRNA stabilization GO:0048255 18 7 0,000 9,261E-03 0,0366481 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,261E-03 0,03658792 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,261E-03 0,03652794 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,261E-03 0,03646815 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,261E-03 0,03640857 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,261E-03 0,03634917 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,261E-03 0,03628997 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,261E-03 0,03623096 ! lipoprotein transport GO:0042953 14 7 0,000 9,261E-03 0,03617215 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,261E-03 0,03611352 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,261E-03 0,03605508 ! rhythmic behavior GO:0007622 15 7 0,000 9,261E-03 0,03599684 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,261E-03 0,03593878 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,261E-03 0,03588091 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,261E-03 0,03582322 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,261E-03 0,03576572 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,261E-03 0,0357084 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,261E-03 0,03565127 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,261E-03 0,03559432 ! mechanosensory behavior GO:0007638 14 7 0,000 9,261E-03 0,03553755 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,261E-03 0,03548096 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,261E-03 0,03542455 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,261E-03 0,03536832 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,261E-03 0,03531227 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,261E-03 0,0352564 ! spinal cord patterning GO:0021511 13 7 0,000 9,261E-03 0,0352007 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,261E-03 0,03514518 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,261E-03 0,03508983 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,261E-03 0,03503466 ! adrenal gland development GO:0030325 17 7 0,000 9,261E-03 0,03497966 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,261E-03 0,03492483 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,261E-03 0,03487018 ! ovulation GO:0030728 9 7 0,000 9,261E-03 0,03481569 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,261E-03 0,03476138 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,261E-03 0,03470723 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,261E-03 0,03465325 ! microtubule nucleation GO:0007020 20 7 0,000 9,261E-03 0,03459944 ! proline biosynthetic process GO:0006561 10 7 0,000 9,261E-03 0,0345458 ! thyroid hormone generation GO:0006590 13 7 0,000 9,261E-03 0,03449233 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 9,261E-03 0,03443901 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,261E-03 0,03438587 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,261E-03 0,03433288 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,261E-03 0,03428006 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,261E-03 0,03422741 ! galactose metabolic process GO:0006012 13 7 0,000 9,261E-03 0,03417491 ! vesicle fusion GO:0006906 17 7 0,000 9,261E-03 0,03412258 ! response to dietary excess GO:0002021 8 7 0,000 9,261E-03 0,0340704 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,261E-03 0,03401839 ! intracellular pH reduction GO:0051452 11 7 0,000 9,261E-03 0,03396653 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,261E-03 0,03391483 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,261E-03 0,03386329 ! organ growth GO:0035265 15 7 0,000 9,261E-03 0,0338119 ! purine salvage GO:0043101 10 7 0,000 9,261E-03 0,03376067 ! nucleoside transport GO:0015858 8 7 0,000 9,261E-03 0,03370959 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,261E-03 0,03365867 ! parturition GO:0007567 14 7 0,000 9,261E-03 0,03360791 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,261E-03 0,03355729 ! rRNA modification GO:0000154 14 7 0,000 9,261E-03 0,03350683 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,261E-03 0,03345652 ! spindle checkpoint GO:0031577 15 7 0,000 9,261E-03 0,03340636 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 9,261E-03 0,03335635 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,261E-03 0,03330649 ! macrophage differentiation GO:0030225 11 7 0,000 9,261E-03 0,03325678 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,261E-03 0,03320722 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,261E-03 0,0331578 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,261E-03 0,03310853 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,261E-03 0,03305941 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,261E-03 0,03301043 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,261E-03 0,0329616 ! fibrinolysis GO:0042730 10 7 0,000 9,261E-03 0,03291291 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,261E-03 0,03286437 ! eating behavior GO:0042755 7 7 0,000 9,261E-03 0,03281597 ! B cell lineage commitment GO:0002326 21 7 0,000 9,261E-03 0,03276771 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,261E-03 0,03271959 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,261E-03 0,03267162 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,261E-03 0,03262378 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,261E-03 0,03257609 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,261E-03 0,03252853 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,261E-03 0,03248111 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,261E-03 0,03243383 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,261E-03 0,03238669 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,261E-03 0,03233968 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,261E-03 0,03229281 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,261E-03 0,03224608 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,261E-03 0,03219948 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,261E-03 0,03215302 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,261E-03 0,03210669 ! regulation of meiosis GO:0040020 12 7 0,000 9,261E-03 0,03206049 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,261E-03 0,03201443 ! T cell lineage commitment GO:0002360 16 7 0,000 9,261E-03 0,0319685 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,261E-03 0,0319227 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,261E-03 0,03187703 ! oxygen homeostasis GO:0032364 12 7 0,000 9,261E-03 0,03183149 ! transcription termination GO:0006353 13 7 0,000 9,261E-03 0,03178608 ! response to tumor cell GO:0002347 13 7 0,000 9,261E-03 0,0317408 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,261E-03 0,03169565 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,261E-03 0,03165063 ! anaphase GO:0051322 17 7 0,000 9,261E-03 0,03160573 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,261E-03 0,03156097 ! axonal fasciculation GO:0007413 18 7 0,000 9,261E-03 0,03151633 ! negative regulation of nuclear division GO:0051784 14 7 0,000 9,261E-03 0,03147181 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,261E-03 0,03142742 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,261E-03 0,03138316 ! diuresis GO:0030146 12 7 0,000 9,261E-03 0,03133902 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,261E-03 0,031295 ! thiamin metabolic process GO:0006772 7 7 0,000 9,261E-03 0,03125111 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,261E-03 0,03120734 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,261E-03 0,0311637 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,261E-03 0,03112017 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,261E-03 0,03107677 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,261E-03 0,03103348 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,261E-03 0,03099032 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,261E-03 0,03094728 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,261E-03 0,03090436 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,261E-03 0,03086155 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,261E-03 0,03081887 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,261E-03 0,0307763 ! lymph node development GO:0048535 10 7 0,000 9,261E-03 0,03073385 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,261E-03 0,03069152 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,261E-03 0,0306493 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,261E-03 0,0306072 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,261E-03 0,03056522 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,261E-03 0,03052335 ! adult feeding behavior GO:0008343 9 7 0,000 9,261E-03 0,03048159 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,261E-03 0,03043995 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,261E-03 0,03039842 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,261E-03 0,03035701 ! muscle adaptation GO:0043500 14 7 0,000 9,261E-03 0,0303157 ! embryonic heart tube development GO:0035050 10 7 0,000 9,261E-03 0,03027451 ! retina homeostasis GO:0001895 12 7 0,000 9,261E-03 0,03023344 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,261E-03 0,03019247 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,261E-03 0,03015161 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,261E-03 0,03011087 ! protein prenylation GO:0018342 18 7 0,000 9,261E-03 0,03007023 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 9,261E-03 0,03002971 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 9,261E-03 0,02998929 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,261E-03 0,02994898 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01057719 0,03415936 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01057719 0,03411357 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01057719 0,0340679 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01057719 0,03402236 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01057719 0,03397693 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01057719 0,03393163 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01057719 0,03388645 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01057719 0,03384139 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01057719 0,03379644 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01057719 0,03375162 ! meiotic prophase I GO:0007128 13 8 0,000 0,01057719 0,03370692 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01057719 0,03366233 ! oligopeptide transport GO:0006857 15 8 0,000 0,01057719 0,03361786 ! UTP metabolic process GO:0046051 8 8 0,000 0,01057719 0,03357351 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01057719 0,03352928 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01057719 0,03348516 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01057719 0,03344116 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01057719 0,03339727 ! succinate metabolic process GO:0006105 14 8 0,000 0,01057719 0,0333535 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01057719 0,03330985 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01057719 0,0332663 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01057719 0,03322287 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01057719 0,03317956 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01057719 0,03313636 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01057719 0,03309327 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01057719 0,03305029 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01057719 0,03300742 ! reflex GO:0060004 16 8 0,000 0,01057719 0,03296467 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01057719 0,03292202 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01057719 0,03287949 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01057719 0,03283706 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01057719 0,03279474 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01057719 0,03275254 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01057719 0,03271044 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01057719 0,03266845 ! pigment granule organization GO:0048753 16 8 0,000 0,01057719 0,03262657 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01057719 0,03258479 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01057719 0,03254312 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01057719 0,03250156 ! histidine metabolic process GO:0006547 16 8 0,000 0,01057719 0,0324601 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01057719 0,03241875 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01057719 0,03237751 ! glycine catabolic process GO:0006546 13 8 0,000 0,01057719 0,03233637 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01057719 0,03229533 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01057719 0,0322544 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01057719 0,03221357 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01057719 0,03217285 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01057719 0,03213222 ! melanin metabolic process GO:0006582 15 8 0,000 0,01057719 0,0320917 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01057719 0,03205129 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01057719 0,03201097 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01057719 0,03197076 ! macrophage activation GO:0042116 12 8 0,000 0,01057719 0,03193064 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01057719 0,03189063 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01057719 0,03185072 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01057719 0,0318109 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01057719 0,03177119 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01057719 0,03173157 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01057719 0,03169206 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01057719 0,03165264 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01057719 0,03161332 ! osteoblast development GO:0002076 16 8 0,000 0,01057719 0,0315741 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01057719 0,03153497 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01057719 0,03149594 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01057719 0,03145701 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01057719 0,03141817 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01057719 0,03137943 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01057719 0,03134079 ! response to UV-B GO:0010224 16 8 0,000 0,01057719 0,03130224 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01057719 0,03126379 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01057719 0,03122543 ! intermediate filament organization GO:0045109 12 8 0,000 0,01057719 0,03118716 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01057719 0,03114899 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01057719 0,03111091 ! cellular extravasation GO:0045123 12 8 0,000 0,01057719 0,03107292 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01057719 0,03103503 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01057719 0,03099722 ! response to antibiotic GO:0046677 11 8 0,000 0,01057719 0,03095952 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01057719 0,0309219 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01057719 0,03088437 ! DNA topological change GO:0006265 12 8 0,000 0,01057719 0,03084694 ! response to tropane GO:0014073 15 8 0,000 0,01057719 0,03080959 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01057719 0,03077234 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01057719 0,03073517 ! melanosome transport GO:0032402 13 8 0,000 0,01057719 0,0306981 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01057719 0,03066111 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01057719 0,03062421 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01057719 0,03058741 ! mast cell activation GO:0045576 14 8 0,000 0,01057719 0,03055069 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01057719 0,03051405 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01057719 0,03047751 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01057719 0,03044105 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01057719 0,03040469 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01057719 0,0303684 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01057719 0,03033221 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01057719 0,0302961 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01057719 0,03026007 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01057719 0,03022413 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01057719 0,03018828 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01057719 0,03015251 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01057719 0,03011683 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01057719 0,03008123 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01057719 0,03004572 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01057719 0,03001028 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01057719 0,02997494 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01057719 0,02993967 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01057719 0,02990449 ! hormone catabolic process GO:0042447 17 8 0,000 0,01057719 0,02986939 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01057719 0,02983437 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01057719 0,02979944 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01057719 0,02976459 ! ATP catabolic process GO:0006200 11 8 0,000 0,01057719 0,02972982 ! blastocyst growth GO:0001832 19 8 0,000 0,01057719 0,02969512 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01057719 0,02966051 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01057719 0,02962599 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01057719 0,02959154 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01057719 0,02955717 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01057719 0,02952288 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01057719 0,02948867 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01057719 0,02945454 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01057719 0,02942049 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01057719 0,02938651 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01057719 0,02935262 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01057719 0,0293188 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01057719 0,02928507 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01057719 0,0292514 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01057719 0,02921782 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01057719 0,02918431 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01057719 0,02915088 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01057719 0,02911753 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01189165 0,03269863 ! axon extension GO:0048675 15 9 0,000 0,01189165 0,0326613 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01189165 0,03262406 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01189165 0,0325869 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01189165 0,03254983 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01189165 0,03251284 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01189165 0,03247594 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01189165 0,03243911 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01189165 0,03240238 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01189165 0,03236572 ! phosphate transport GO:0006817 19 9 0,000 0,01189165 0,03232915 ! reproductive behavior GO:0019098 19 9 0,000 0,01189165 0,03229266 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01189165 0,03225626 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01189165 0,03221993 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01189165 0,03218369 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01189165 0,03214753 ! GTP metabolic process GO:0046039 9 9 0,000 0,01189165 0,03211145 ! RNA methylation GO:0001510 15 9 0,000 0,01189165 0,03207545 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01189165 0,03203953 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01189165 0,03200369 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01189165 0,03196793 ! artery development GO:0060840 24 9 0,000 0,01189165 0,03193225 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01189165 0,03189665 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01189165 0,03186114 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01189165 0,03182569 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01189165 0,03179033 ! chemosensory behavior GO:0007635 20 9 0,000 0,01189165 0,03175505 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01189165 0,03171984 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01189165 0,03168472 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01189165 0,03164967 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01189165 0,0316147 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01189165 0,0315798 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01189165 0,03154498 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01189165 0,03151024 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01189165 0,03147558 ! protein targeting to ER GO:0045047 22 9 0,000 0,01189165 0,03144099 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01189165 0,03140648 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01189165 0,03137204 ! T cell selection GO:0045058 23 9 0,000 0,01189165 0,03133768 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01189165 0,03130339 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01189165 0,03126918 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01189165 0,03123504 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01189165 0,03120098 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01189165 0,03116699 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01189165 0,03113308 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01189165 0,03109924 ! mannose metabolic process GO:0006013 13 9 0,000 0,01189165 0,03106547 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01189165 0,03103178 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01189165 0,03099816 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01189165 0,03096461 ! receptor clustering GO:0043113 18 9 0,000 0,01189165 0,03093113 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01189165 0,03089773 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01189165 0,0308644 ! ruffle organization GO:0031529 15 9 0,000 0,01189165 0,03083114 ! retinol metabolic process GO:0042572 18 9 0,000 0,01189165 0,03079795 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01189165 0,03076484 ! behavioral fear response GO:0001662 22 9 0,000 0,01189165 0,03073179 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01189165 0,03069882 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01189165 0,03066592 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01189165 0,03063308 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01189165 0,03060032 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01189165 0,03056763 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01189165 0,030535 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01189165 0,03050245 ! segment specification GO:0007379 13 9 0,000 0,01189165 0,03046997 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01189165 0,03043755 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01189165 0,03040521 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01189165 0,03037293 ! response to amine stimulus GO:0014075 13 9 0,000 0,01189165 0,03034072 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01189165 0,03030858 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01189165 0,03027651 ! erythrocyte development GO:0048821 15 9 0,000 0,01189165 0,0302445 ! gas homeostasis GO:0033483 16 9 0,000 0,01189165 0,03021257 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01189165 0,0301807 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01189165 0,03014889 ! renal water homeostasis GO:0003091 14 9 0,000 0,01189165 0,03011716 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01189165 0,03008549 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01189165 0,03005389 ! icosanoid secretion GO:0032309 15 9 0,000 0,01189165 0,03002235 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01189165 0,02999088 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01189165 0,02995948 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01189165 0,02992814 ! regulation of cell division GO:0051302 15 9 0,000 0,01189165 0,02989686 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01189165 0,02986566 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01189165 0,02983451 ! sterol catabolic process GO:0016127 11 9 0,000 0,01189165 0,02980344 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01189165 0,02977242 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01189165 0,02974148 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01189165 0,02971059 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01189165 0,02967977 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01189165 0,02964901 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01189165 0,02961832 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01189165 0,02958769 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01189165 0,02955713 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01189165 0,02952662 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01189165 0,02949618 ! purine base metabolic process GO:0006144 21 9 0,000 0,01189165 0,02946581 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01189165 0,02943549 ! pigment granule transport GO:0051904 17 9 0,000 0,01189165 0,02940524 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01189165 0,02937505 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01189165 0,02934492 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01189165 0,02931486 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01189165 0,02928485 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01189165 0,02925491 ! mitochondrion localization GO:0051646 15 9 0,000 0,01189165 0,02922502 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0132044 0,03241814 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0132044 0,0323851 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0132044 0,03235212 ! synapsis GO:0007129 13 10 0,000 0,0132044 0,03231921 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0132044 0,03228636 ! N-glycan processing GO:0006491 20 10 0,000 0,0132044 0,03225358 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0132044 0,03222087 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0132044 0,03218823 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0132044 0,03215565 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0132044 0,03212313 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0132044 0,03209069 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0132044 0,03205831 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0132044 0,03202599 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0132044 0,03199374 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0132044 0,03196155 ! androgen metabolic process GO:0008209 17 10 0,000 0,0132044 0,03192943 ! phospholipid efflux GO:0033700 16 10 0,000 0,0132044 0,03189737 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0132044 0,03186538 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0132044 0,03183345 ! lung alveolus development GO:0048286 26 10 0,000 0,0132044 0,03180158 ! pathogenesis GO:0009405 13 10 0,000 0,0132044 0,03176978 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0132044 0,03173804 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0132044 0,03170637 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0132044 0,03167476 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0132044 0,03164321 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0132044 0,03161172 ! endoderm development GO:0007492 16 10 0,000 0,0132044 0,0315803 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0132044 0,03154894 ! arginine catabolic process GO:0006527 13 10 0,000 0,0132044 0,03151764 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0132044 0,0314864 ! proline metabolic process GO:0006560 13 10 0,000 0,0132044 0,03145523 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0132044 0,03142412 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0132044 0,03139306 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0132044 0,03136207 ! V(D)J recombination GO:0033151 28 10 0,000 0,0132044 0,03133114 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0132044 0,03130028 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0132044 0,03126947 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0132044 0,03123872 ! B cell proliferation GO:0042100 18 10 0,000 0,0132044 0,03120804 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0132044 0,03117741 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0132044 0,03114684 ! multicellular organism growth GO:0035264 18 10 0,000 0,0132044 0,03111634 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0132044 0,03108589 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0132044 0,0310555 ! epithelial cell development GO:0002064 20 10 0,000 0,0132044 0,03102518 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0132044 0,03099491 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0132044 0,0309647 ! macroautophagy GO:0016236 17 10 0,000 0,0132044 0,03093455 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0132044 0,03090446 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0132044 0,03087442 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0132044 0,03084445 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0132044 0,03081453 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0132044 0,03078467 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0132044 0,03075487 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0132044 0,03072513 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0132044 0,03069544 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0132044 0,03066581 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0132044 0,03063624 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0132044 0,03060672 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0132044 0,03057727 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0132044 0,03054787 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0132044 0,03051852 ! response to dsRNA GO:0043331 20 10 0,000 0,0132044 0,03048923 ! DNA ligation GO:0006266 19 10 0,000 0,0132044 0,03046 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0132044 0,03043082 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0132044 0,0304017 ! melanosome localization GO:0032400 16 10 0,000 0,0132044 0,03037264 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0132044 0,03034363 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0132044 0,03031468 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0132044 0,03028578 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0132044 0,03025693 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0132044 0,03022815 ! mRNA cleavage GO:0006379 17 10 0,000 0,0132044 0,03019941 ! protein sumoylation GO:0016925 15 10 0,000 0,0132044 0,03017073 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0132044 0,03014211 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0132044 0,03011354 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0132044 0,03008502 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0132044 0,03005656 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0132044 0,03002815 ! salivary gland development GO:0007431 27 10 0,000 0,0132044 0,02999979 ! prophase GO:0051324 15 10 0,000 0,0132044 0,02997149 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0132044 0,02994324 ! apical protein localization GO:0045176 15 10 0,000 0,0132044 0,02991505 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0132044 0,02988691 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0132044 0,02985882 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0132044 0,02983078 ! midbrain development GO:0030901 13 10 0,000 0,0132044 0,0298028 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0132044 0,02977486 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0132044 0,02974699 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0132044 0,02971916 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0132044 0,02969138 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0132044 0,02966366 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0132044 0,02963599 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0132044 0,02960837 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0132044 0,0295808 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0132044 0,02955328 ! oocyte development GO:0048599 17 10 0,000 0,0132044 0,02952582 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0132044 0,0294984 ! blastocyst formation GO:0001825 17 10 0,000 0,0132044 0,02947104 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0132044 0,02944373 ! activation of innate immune response GO:0002218 12 10 0,000 0,0132044 0,02941646 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0132044 0,02938925 ! response to nicotine GO:0035094 20 10 0,000 0,0132044 0,02936209 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0132044 0,02933498 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0132044 0,02930792 ! localization within membrane GO:0051668 20 10 0,000 0,0132044 0,0292809 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01451545 0,03215854 ! respiratory burst GO:0045730 17 11 0,000 0,01451545 0,03212895 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01451545 0,03209942 ! neuron fate specification GO:0048665 17 11 0,000 0,01451545 0,03206994 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01451545 0,03204052 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01451545 0,03201115 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01451545 0,03198184 ! thyroid gland development GO:0030878 26 11 0,000 0,01451545 0,03195258 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01451545 0,03192337 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01451545 0,03189422 ! response to pain GO:0048265 24 11 0,000 0,01451545 0,03186512 ! T cell proliferation GO:0042098 26 11 0,000 0,01451545 0,03183607 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01451545 0,03180708 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01451545 0,03177813 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01451545 0,03174925 ! bone resorption GO:0045453 16 11 0,000 0,01451545 0,03172041 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01451545 0,03169162 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01451545 0,03166289 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01451545 0,03163421 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01451545 0,03160558 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01451545 0,03157701 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01451545 0,03154848 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01451545 0,03152001 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01451545 0,03149159 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01451545 0,03146322 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01451545 0,0314349 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01451545 0,03140663 ! lipid digestion GO:0044241 18 11 0,000 0,01451545 0,03137841 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01451545 0,03135024 ! UV protection GO:0009650 19 11 0,000 0,01451545 0,03132213 ! adult heart development GO:0007512 14 11 0,000 0,01451545 0,03129406 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01451545 0,03126604 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01451545 0,03123808 ! temperature homeostasis GO:0001659 17 11 0,000 0,01451545 0,03121016 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01451545 0,03118229 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01451545 0,03115448 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01451545 0,03112671 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01451545 0,03109899 ! regulation of organ growth GO:0046620 13 11 0,000 0,01451545 0,03107133 ! pigment granule localization GO:0051875 20 11 0,000 0,01451545 0,03104371 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01451545 0,03101614 ! vasoconstriction GO:0042310 18 11 0,000 0,01451545 0,03098862 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01451545 0,03096114 ! embryonic axis specification GO:0000578 18 11 0,000 0,01451545 0,03093372 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01451545 0,03090635 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01451545 0,03087902 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01451545 0,03085174 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01451545 0,03082451 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01451545 0,03079733 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01451545 0,03077019 ! zymogen activation GO:0031638 15 11 0,000 0,01451545 0,03074311 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01451545 0,03071607 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01451545 0,03068908 ! nucleosome positioning GO:0016584 15 11 0,000 0,01451545 0,03066213 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01451545 0,03063524 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01451545 0,03060839 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01451545 0,03058158 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01451545 0,03055483 ! acid secretion GO:0046717 18 11 0,000 0,01451545 0,03052812 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01451545 0,03050146 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01451545 0,03047484 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01451545 0,03044827 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01451545 0,03042175 ! oocyte differentiation GO:0009994 18 11 0,000 0,01451545 0,03039527 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01451545 0,03036884 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01451545 0,03034246 ! cholesterol efflux GO:0033344 19 11 0,000 0,01451545 0,03031612 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01451545 0,03028983 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01451545 0,03026358 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01451545 0,03023738 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01451545 0,03021122 ! embryonic gut development GO:0048566 15 11 0,000 0,01451545 0,03018511 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01451545 0,03015904 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01451545 0,03013302 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01451545 0,03010704 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01451545 0,03008111 ! defense response to fungus GO:0050832 13 11 0,000 0,01451545 0,03005522 ! developmental induction GO:0031128 19 11 0,000 0,01451545 0,03002938 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01451545 0,03000358 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01451545 0,02997783 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01451545 0,02995212 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01451545 0,02992645 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01451545 0,02990083 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01451545 0,02987525 ! nucleus localization GO:0051647 19 11 0,000 0,01451545 0,02984972 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01451545 0,02982423 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0158248 0,03248675 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0158248 0,03245906 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0158248 0,03243141 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0158248 0,03240381 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0158248 0,03237625 ! virus-host interaction GO:0019048 29 12 0,000 0,0158248 0,03234875 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0158248 0,03232128 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0158248 0,03229387 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0158248 0,0322665 ! protein complex disassembly GO:0043241 27 12 0,000 0,0158248 0,03223918 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0158248 0,03221191 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0158248 0,03218468 ! hippocampus development GO:0021766 26 12 0,000 0,0158248 0,03215749 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0158248 0,03213036 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0158248 0,03210327 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0158248 0,03207622 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0158248 0,03204922 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0158248 0,03202227 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0158248 0,03199536 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0158248 0,03196849 ! drug transport GO:0015893 16 12 0,000 0,0158248 0,03194167 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0158248 0,0319149 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0158248 0,03188817 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0158248 0,03186148 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0158248 0,03183484 ! focal adhesion formation GO:0048041 35 12 0,000 0,0158248 0,03180825 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0158248 0,0317817 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0158248 0,03175519 ! forebrain cell migration GO:0021885 21 12 0,000 0,0158248 0,03172873 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0158248 0,03170231 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0158248 0,03167593 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0158248 0,0316496 ! entry into host cell GO:0030260 32 12 0,000 0,0158248 0,03162332 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0158248 0,03159707 ! monoamine transport GO:0015844 18 12 0,000 0,0158248 0,03157087 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0158248 0,03154472 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0158248 0,0315186 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0158248 0,03149253 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0158248 0,03146651 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0158248 0,03144052 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0158248 0,03141458 ! protein homotetramerization GO:0051289 21 12 0,000 0,0158248 0,03138868 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0158248 0,03136283 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0158248 0,03133702 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0158248 0,03131124 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0158248 0,03128552 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0158248 0,03125983 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0158248 0,03123419 ! cranial nerve development GO:0021545 20 12 0,000 0,0158248 0,03120858 ! fucose catabolic process GO:0019317 22 12 0,000 0,0158248 0,03118302 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0158248 0,03115751 ! histone acetylation GO:0016573 26 12 0,000 0,0158248 0,03113203 ! histone methylation GO:0016571 26 12 0,000 0,0158248 0,0311066 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0158248 0,0310812 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0158248 0,03105585 ! gland morphogenesis GO:0022612 29 12 0,000 0,0158248 0,03103054 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0158248 0,03100527 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0158248 0,03098004 ! T cell homeostasis GO:0043029 25 12 0,000 0,0158248 0,03095486 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0158248 0,03092971 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0158248 0,03090461 ! spleen development GO:0048536 22 12 0,000 0,0158248 0,03087954 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0158248 0,03085452 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0158248 0,03082953 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0158248 0,03080459 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0158248 0,03077969 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0158248 0,03075483 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0158248 0,03073 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0158248 0,03070522 ! response to cold GO:0009409 17 12 0,000 0,0158248 0,03068048 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0158248 0,03065578 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0158248 0,03063111 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01713246 0,03313561 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01713246 0,03310899 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01713246 0,03308242 ! peroxisomal transport GO:0043574 24 13 0,000 0,01713246 0,03305589 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01713246 0,0330294 ! lipid localization GO:0010876 28 13 0,000 0,01713246 0,03300296 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01713246 0,03297656 ! organelle fusion GO:0048284 32 13 0,000 0,01713246 0,0329502 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01713246 0,03292388 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01713246 0,0328976 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01713246 0,03287137 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01713246 0,03284518 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01713246 0,03281903 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01713246 0,03279292 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01713246 0,03276685 ! methionine metabolic process GO:0006555 27 13 0,000 0,01713246 0,03274082 ! plasma membrane organization GO:0007009 24 13 0,000 0,01713246 0,03271484 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01713246 0,03268889 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01713246 0,03266299 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01713246 0,03263713 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01713246 0,03261131 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01713246 0,03258553 ! response to X-ray GO:0010165 25 13 0,000 0,01713246 0,03255979 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01713246 0,03253409 ! exocrine system development GO:0035272 32 13 0,000 0,01713246 0,03250844 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01713246 0,03248282 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01713246 0,03245724 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01713246 0,0324317 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01713246 0,03240621 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01713246 0,03238075 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01713246 0,03235533 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01713246 0,03232996 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01713246 0,03230462 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01713246 0,03227932 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01713246 0,03225407 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01713246 0,03222885 ! ribosome assembly GO:0042255 17 13 0,000 0,01713246 0,03220367 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01713246 0,03217853 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01713246 0,03215343 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01713246 0,03212837 ! chromatin silencing GO:0006342 26 13 0,000 0,01713246 0,03210335 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01713246 0,03207836 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01713246 0,03205342 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01713246 0,03202851 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01713246 0,03200365 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01713246 0,03197882 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01713246 0,03195403 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01713246 0,03192928 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01713246 0,03190456 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01713246 0,03187989 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01713246 0,03185525 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01713246 0,03183065 ! embryonic placenta development GO:0001892 23 13 0,000 0,01713246 0,03180609 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01713246 0,03178157 ! insulin secretion GO:0030073 23 13 0,000 0,01713246 0,03175708 ! actin filament polymerization GO:0030041 24 13 0,000 0,01713246 0,03173264 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01713246 0,03170823 ! acrosome reaction GO:0007340 18 13 0,000 0,01713246 0,03168386 ! rRNA transcription GO:0009303 25 14 0,000 0,01843842 0,03407284 ! lactation GO:0007595 26 14 0,000 0,01843842 0,03404669 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01843842 0,03402058 ! reproductive cellular process GO:0048610 20 14 0,000 0,01843842 0,03399451 ! tRNA modification GO:0006400 20 14 0,000 0,01843842 0,03396849 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01843842 0,0339425 ! regulation of S phase GO:0033261 23 14 0,000 0,01843842 0,03391655 ! water transport GO:0006833 21 14 0,000 0,01843842 0,03389064 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01843842 0,03386476 ! non-recombinational repair GO:0000726 25 14 0,000 0,01843842 0,03383893 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01843842 0,03381314 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01843842 0,03378739 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01843842 0,03376168 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01843842 0,033736 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01843842 0,03371037 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01843842 0,03368477 ! palate development GO:0060021 31 14 0,000 0,01843842 0,03365921 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01843842 0,03363369 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01843842 0,03360821 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01843842 0,03358277 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01843842 0,03355737 ! arginine metabolic process GO:0006525 17 14 0,000 0,01843842 0,033532 ! regulation of heart rate GO:0002027 24 14 0,000 0,01843842 0,03350668 ! organic alcohol transport GO:0015850 29 14 0,000 0,01843842 0,03348139 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01843842 0,03345614 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01843842 0,03343093 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01843842 0,03340575 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01843842 0,03338062 ! L-amino acid transport GO:0015807 30 14 0,000 0,01843842 0,03335552 ! bone mineralization GO:0030282 17 14 0,000 0,01843842 0,03333046 ! stem cell development GO:0048864 43 14 0,000 0,01843842 0,03330544 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01843842 0,03328045 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01843842 0,0332555 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01843842 0,03323059 ! cerebellum development GO:0021549 21 14 0,000 0,01843842 0,03320572 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01843842 0,03318088 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01843842 0,03315609 ! response to gamma radiation GO:0010332 28 14 0,000 0,01843842 0,03313132 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01843842 0,0331066 ! cofactor transport GO:0051181 26 14 0,000 0,01843842 0,03308191 ! NADP metabolic process GO:0006739 24 14 0,000 0,01843842 0,03305726 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01843842 0,03303264 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01843842 0,03300807 ! intestinal absorption GO:0050892 25 14 0,000 0,01843842 0,03298353 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01843842 0,03295902 ! oxygen transport GO:0015671 21 14 0,000 0,01843842 0,03293455 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01843842 0,03291012 ! male genitalia development GO:0030539 24 14 0,000 0,01843842 0,03288572 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01843842 0,03286136 ! regulation of axon extension GO:0030516 37 14 0,000 0,01843842 0,03283704 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01843842 0,03281275 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01974269 0,03510785 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01974269 0,03508192 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,01974269 0,03505603 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01974269 0,03503018 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01974269 0,03500436 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01974269 0,03497858 ! copper ion transport GO:0006825 20 15 0,000 0,01974269 0,03495285 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01974269 0,03492715 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01974269 0,03490148 ! sulfate transport GO:0008272 23 15 0,000 0,01974269 0,03487586 ! response to cAMP GO:0051591 22 15 0,000 0,01974269 0,03485027 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01974269 0,03482472 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01974269 0,03479921 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01974269 0,03477373 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01974269 0,03474829 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01974269 0,03472289 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01974269 0,03469753 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01974269 0,0346722 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01974269 0,03464691 ! pituitary gland development GO:0021983 29 15 0,000 0,01974269 0,03462166 ! vesicle coating GO:0006901 33 15 0,000 0,01974269 0,03459644 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01974269 0,03457126 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01974269 0,03454612 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01974269 0,03452102 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01974269 0,03449595 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01974269 0,03447091 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01974269 0,03444592 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01974269 0,03442095 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01974269 0,03439603 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01974269 0,03437114 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01974269 0,03434629 ! histone deacetylation GO:0016575 20 15 0,000 0,01974269 0,03432147 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01974269 0,03429669 ! tissue regeneration GO:0042246 26 15 0,000 0,01974269 0,03427195 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01974269 0,03424724 ! water homeostasis GO:0030104 27 15 0,000 0,01974269 0,03422256 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01974269 0,03419792 ! muscle maintenance GO:0046716 26 15 0,000 0,01974269 0,03417332 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01974269 0,03414875 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01974269 0,03412422 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01974269 0,03409973 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01974269 0,03407526 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01974269 0,03405084 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01974269 0,03402645 ! detection of bacterium GO:0016045 18 15 0,000 0,01974269 0,03400209 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01974269 0,03397777 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01974269 0,03395348 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01974269 0,03392923 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01974269 0,03390501 ! peptide hormone processing GO:0016486 23 15 0,000 0,01974269 0,03388083 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02104527 0,03609047 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02104527 0,03606476 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02104527 0,03603909 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02104527 0,03601346 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02104527 0,03598787 ! bone remodeling GO:0046849 27 16 0,000 0,02104527 0,03596231 ! filopodium assembly GO:0046847 32 16 0,000 0,02104527 0,03593678 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02104527 0,0359113 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02104527 0,03588584 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02104527 0,03586043 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02104527 0,03583505 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02104527 0,03580971 ! startle response GO:0001964 28 16 0,000 0,02104527 0,0357844 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02104527 0,03575913 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02104527 0,03573389 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02104527 0,03570869 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02104527 0,03568353 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02104527 0,0356584 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02104527 0,03563331 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02104527 0,03560825 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02104527 0,03558322 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02104527 0,03555824 ! response to osmotic stress GO:0006970 25 16 0,000 0,02104527 0,03553328 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02104527 0,03550836 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02104527 0,03548348 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02104527 0,03545863 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02104527 0,03543382 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02104527 0,03540904 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02104527 0,0353843 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02104527 0,03535959 ! axon cargo transport GO:0008088 43 16 0,000 0,02104527 0,03533491 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02104527 0,03531027 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02104527 0,03528566 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02104527 0,03526109 ! DNA replication initiation GO:0006270 27 16 0,000 0,02104527 0,03523655 ! neuron recognition GO:0008038 35 16 0,000 0,02104527 0,03521205 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02104527 0,03518758 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02104527 0,03516314 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02104527 0,03513874 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02104527 0,03511437 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02104527 0,03509004 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02104527 0,03506574 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02104527 0,03504147 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02104527 0,03501724 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02104527 0,03499304 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02104527 0,03496887 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02104527 0,03494474 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02104527 0,03492064 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02104527 0,03489657 ! defense response to virus GO:0051607 37 16 0,000 0,02104527 0,03487254 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02234617 0,03700267 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02234617 0,03697722 ! metencephalon development GO:0022037 30 17 0,000 0,02234617 0,03695181 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02234617 0,03692643 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02234617 0,03690108 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02234617 0,03687577 ! signal complex assembly GO:0007172 41 17 0,000 0,02234617 0,0368505 ! endothelial cell migration GO:0043542 28 17 0,000 0,02234617 0,03682526 ! inositol metabolic process GO:0006020 28 17 0,000 0,02234617 0,03680005 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02234617 0,03677488 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02234617 0,03674974 ! glial cell development GO:0021782 27 17 0,000 0,02234617 0,03672464 ! limbic system development GO:0021761 36 17 0,000 0,02234617 0,03669957 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02234617 0,03667454 ! adult walking behavior GO:0007628 33 17 0,000 0,02234617 0,03664954 ! heart looping GO:0001947 30 17 0,000 0,02234617 0,03662458 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02234617 0,03659964 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02234617 0,03657475 ! myoblast differentiation GO:0045445 45 17 0,000 0,02234617 0,03654988 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02234617 0,03652505 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02234617 0,03650026 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02234617 0,03647549 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02234617 0,03645076 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02234617 0,03642607 ! glycine metabolic process GO:0006544 28 17 0,000 0,02234617 0,03640141 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02234617 0,03637678 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02234617 0,03635218 ! NAD metabolic process GO:0019674 29 17 0,000 0,02234617 0,03632762 ! DNA integration GO:0015074 29 17 0,000 0,02234617 0,03630309 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02234617 0,03627859 ! regulation of protein binding GO:0043393 33 17 0,000 0,02234617 0,03625413 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02234617 0,0362297 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02234617 0,0362053 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02234617 0,03618094 ! genitalia development GO:0048806 30 17 0,000 0,02234617 0,03615661 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02234617 0,03613231 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02234617 0,03610804 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02234617 0,03608381 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02234617 0,03605961 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02234617 0,03603544 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02234617 0,0360113 ! steroid catabolic process GO:0006706 31 17 0,000 0,02234617 0,0359872 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02234617 0,03596313 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02234617 0,03593909 ! gas transport GO:0015669 25 17 0,000 0,02234617 0,03591508 ! organic cation transport GO:0015695 31 17 0,000 0,02234617 0,03589111 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02234617 0,03586716 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02234617 0,03584325 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02234617 0,03581937 ! microspike assembly GO:0030035 36 17 0,000 0,02234617 0,03579552 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02234617 0,03577171 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02234617 0,03574792 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02364537 0,03780118 ! neuron maturation GO:0042551 42 18 0,000 0,02364537 0,03777608 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02364537 0,03775101 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02364537 0,03772598 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02364537 0,03770097 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02364537 0,03767601 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02364537 0,03765107 ! memory GO:0007613 31 18 0,000 0,02364537 0,03762617 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02364537 0,0376013 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02364537 0,03757647 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02364537 0,03755166 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02364537 0,03752689 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02364537 0,03750216 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02364537 0,03747745 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02364537 0,03745278 ! response to retinoic acid GO:0032526 26 18 0,000 0,02364537 0,03742814 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02364537 0,03740353 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02364537 0,03737896 ! response to fungus GO:0009620 21 18 0,000 0,02364537 0,03735441 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02364537 0,0373299 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02364537 0,03730542 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02364537 0,03728098 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02364537 0,03725656 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02364537 0,03723218 ! vitamin transport GO:0051180 27 18 0,000 0,02364537 0,03720783 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02364537 0,03718351 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02364537 0,03715922 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02364537 0,03713497 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02364537 0,03711074 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02364537 0,03708655 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02364537 0,03706239 ! nerve development GO:0021675 28 18 0,000 0,02364537 0,03703826 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02364537 0,03701416 ! protein secretion GO:0009306 39 19 0,000 0,0249429 0,03901991 ! positive regulation of translation GO:0045727 30 19 0,000 0,0249429 0,03899455 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0249429 0,03896923 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0249429 0,03894394 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0249429 0,03891869 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0249429 0,03889346 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0249429 0,03886827 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0249429 0,03884312 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0249429 0,03881799 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0249429 0,0387929 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0249429 0,03876784 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0249429 0,03874281 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0249429 0,03871782 ! cerebral cortex development GO:0021987 36 19 0,000 0,0249429 0,03869285 ! pigmentation during development GO:0048066 41 19 0,000 0,0249429 0,03866792 ! response to vitamin A GO:0033189 27 19 0,000 0,0249429 0,03864302 ! heme metabolic process GO:0042168 36 19 0,000 0,0249429 0,03861816 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0249429 0,03859332 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0249429 0,03856852 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0249429 0,03854375 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0249429 0,03851901 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0249429 0,0384943 ! peptide cross-linking GO:0018149 37 19 0,000 0,0249429 0,03846962 ! protein export from nucleus GO:0006611 36 19 0,000 0,0249429 0,03844498 ! heart process GO:0003015 30 19 0,000 0,0249429 0,03842037 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0249429 0,03839579 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0249429 0,03837124 ! visual learning GO:0008542 36 19 0,000 0,0249429 0,03834672 ! cellular pigmentation GO:0033059 36 19 0,000 0,0249429 0,03832223 ! G1 phase GO:0051318 40 19 0,000 0,0249429 0,03829778 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0249429 0,03827335 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0249429 0,03824896 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0249429 0,03822459 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0249429 0,03820026 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0249429 0,03817596 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0249429 0,03815169 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0249429 0,03812745 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0249429 0,03810325 ! cilium assembly GO:0042384 37 19 0,000 0,0249429 0,03807907 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0249429 0,03805492 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02623874 0,0400066 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02623874 0,03998126 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02623874 0,03995596 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02623874 0,03993068 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02623874 0,03990544 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02623874 0,03988024 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02623874 0,03985506 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02623874 0,03982991 ! response to vitamin GO:0033273 31 20 0,000 0,02623874 0,0398048 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02623874 0,03977972 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02623874 0,03975467 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02623874 0,03972965 ! response to alkaloid GO:0043279 38 20 0,000 0,02623874 0,03970466 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02623874 0,03967971 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02623874 0,03965478 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02623874 0,03962989 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02623874 0,03960503 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02623874 0,0395802 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02623874 0,0395554 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02623874 0,03953063 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02623874 0,03950589 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02623874 0,03948118 ! body fluid secretion GO:0007589 31 20 0,000 0,02623874 0,03945651 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02623874 0,03943186 ! peptide secretion GO:0002790 35 20 0,000 0,02623874 0,03940725 ! stem cell differentiation GO:0048863 53 20 0,000 0,02623874 0,03938267 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02623874 0,03935811 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02623874 0,03933359 ! sensory perception of pain GO:0019233 30 20 0,000 0,02623874 0,0393091 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02623874 0,03928464 ! diencephalon development GO:0021536 34 20 0,000 0,02623874 0,03926021 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02623874 0,03923581 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02623874 0,03921144 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02623874 0,0391871 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02623874 0,03916279 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02623874 0,03913851 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02623874 0,03911426 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02623874 0,03909004 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02623874 0,03906585 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02623874 0,03904169 ! regulation of glucose import GO:0046324 29 20 0,000 0,02623874 0,03901756 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02623874 0,03899346 ! actin filament-based movement GO:0030048 43 20 0,000 0,02623874 0,03896939 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02623874 0,03894535 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02623874 0,03892134 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02623874 0,03889736 ! negative regulation of translation GO:0017148 29 20 0,000 0,02623874 0,03887341 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02623874 0,03884948 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02623874 0,03882559 ! regulation of cell killing GO:0031341 42 21 0,000 0,02753291 0,04071553 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02753291 0,04069052 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02753291 0,04066554 ! hormone secretion GO:0046879 38 21 0,000 0,02753291 0,0406406 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02753291 0,04061568 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02753291 0,04059079 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02753291 0,04056593 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02753291 0,04054111 ! axis specification GO:0009798 38 21 0,000 0,02753291 0,04051631 ! ovarian follicle development GO:0001541 35 21 0,000 0,02753291 0,04049155 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02753291 0,04046681 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02753291 0,04044211 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02753291 0,04041743 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02753291 0,04039279 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02753291 0,04036817 ! cell aging GO:0007569 44 21 0,000 0,02753291 0,04034359 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02753291 0,04031903 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02753291 0,04029451 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02753291 0,04027001 ! cytolysis GO:0019835 24 21 0,000 0,02753291 0,04024555 ! vasodilation GO:0042311 39 21 0,000 0,02753291 0,04022111 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02753291 0,04019671 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02753291 0,04017233 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02753291 0,04014798 ! oogenesis GO:0048477 36 21 0,000 0,02753291 0,04012366 ! DNA modification GO:0006304 34 21 0,000 0,02753291 0,04009938 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02753291 0,04007512 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02753291 0,04005089 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02753291 0,04002669 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02753291 0,04000252 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02753291 0,03997838 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02753291 0,03995426 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02753291 0,03993018 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02753291 0,03990613 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02753291 0,0398821 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02753291 0,03985811 ! collagen catabolic process GO:0030574 28 21 0,000 0,02753291 0,03983414 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02753291 0,0398102 ! gut development GO:0048565 39 21 0,000 0,02753291 0,03978629 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02882539 0,04162899 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02882539 0,04160402 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02882539 0,04157907 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02882539 0,04155416 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02882539 0,04152928 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02882539 0,04150442 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02882539 0,0414796 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02882539 0,04145481 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02882539 0,04143004 ! regeneration GO:0031099 41 22 0,000 0,02882539 0,04140531 ! keratinization GO:0031424 28 22 0,000 0,02882539 0,0413806 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02882539 0,04135593 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02882539 0,04133128 ! sensory perception of taste GO:0050909 28 22 0,000 0,02882539 0,04130667 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02882539 0,04128208 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02882539 0,04125752 ! vacuolar transport GO:0007034 36 22 0,000 0,02882539 0,04123299 ! lysosome organization GO:0007040 41 22 0,000 0,02882539 0,04120849 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02882539 0,04118402 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02882539 0,04115958 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02882539 0,04113517 ! fucose metabolic process GO:0006004 39 22 0,000 0,02882539 0,04111078 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02882539 0,04108643 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02882539 0,0410621 ! ureteric bud development GO:0001657 43 22 0,000 0,02882539 0,04103781 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02882539 0,04101354 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02882539 0,0409893 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02882539 0,04096509 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02882539 0,04094091 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02882539 0,04091675 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02882539 0,04089263 ! sarcomere organization GO:0045214 30 22 0,000 0,02882539 0,04086853 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02882539 0,04084446 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02882539 0,04082042 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02882539 0,04079641 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02882539 0,04077242 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02882539 0,04074847 ! protein stabilization GO:0050821 39 22 0,000 0,02882539 0,04072454 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0301162 0,04252323 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0301162 0,04249829 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0301162 0,04247338 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0301162 0,0424485 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0301162 0,04242365 ! gluconeogenesis GO:0006094 33 23 0,000 0,0301162 0,04239882 ! viral genome replication GO:0019079 41 23 0,000 0,0301162 0,04237403 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0301162 0,04234926 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0301162 0,04232453 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0301162 0,04229982 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0301162 0,04227514 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0301162 0,04225049 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0301162 0,04222587 ! visual behavior GO:0007632 42 23 0,000 0,0301162 0,04220127 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0301162 0,04217671 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0301162 0,04215217 ! response to ethanol GO:0045471 46 23 0,000 0,0301162 0,04212767 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0301162 0,04210319 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,0301162 0,04207874 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0301162 0,04205432 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0301162 0,04202992 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0301162 0,04200556 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0301162 0,04198122 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0301162 0,04195691 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0301162 0,04193263 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0301162 0,04190838 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0301162 0,04188415 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0301162 0,04185996 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0301162 0,04183579 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0301162 0,04181165 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0301162 0,04178754 ! fatty acid transport GO:0015908 44 23 0,000 0,0301162 0,04176345 ! platelet activation GO:0030168 37 23 0,000 0,0301162 0,04173939 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0301162 0,04171536 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0301162 0,04169136 ! hormone transport GO:0009914 40 23 0,000 0,0301162 0,04166739 ! cell-cell recognition GO:0009988 25 23 0,000 0,0301162 0,04164344 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0301162 0,04161952 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0301162 0,04159563 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0301162 0,04157177 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0301162 0,04154793 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0301162 0,04152412 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03140534 0,04327678 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03140534 0,04325201 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03140534 0,04322726 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03140534 0,04320255 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03140534 0,04317786 ! vesicle docking GO:0048278 47 24 0,000 0,03140534 0,0431532 ! spinal cord development GO:0021510 47 24 0,000 0,03140534 0,04312857 ! vacuole organization GO:0007033 43 24 0,000 0,03140534 0,04310397 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03140534 0,04307939 ! digestive system process GO:0022600 39 24 0,000 0,03140534 0,04305485 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03140534 0,04303033 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03140534 0,04300584 ! regulation of behavior GO:0050795 43 24 0,000 0,03140534 0,04298137 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03140534 0,04295694 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03140534 0,04293253 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03140534 0,04290815 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03140534 0,0428838 ! membrane depolarization GO:0051899 39 24 0,000 0,03140534 0,04285948 ! pallium development GO:0021543 49 24 0,000 0,03140534 0,04283518 ! pentose metabolic process GO:0019321 35 24 0,000 0,03140534 0,04281091 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03140534 0,04278667 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03140534 0,04276245 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03140534 0,04273827 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03140534 0,04271411 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03140534 0,04268998 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03140534 0,04266587 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03140534 0,04264179 ! regulation of amine transport GO:0051952 40 24 0,000 0,03140534 0,04261774 ! protein tetramerization GO:0051262 52 24 0,000 0,03140534 0,04259372 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03269281 0,04431488 ! myelination GO:0042552 45 25 0,000 0,03269281 0,04428992 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03269281 0,044265 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03269281 0,0442401 ! phototransduction GO:0007602 33 25 0,000 0,03269281 0,04421524 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03269281 0,0441904 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03269281 0,04416558 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03269281 0,0441408 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03269281 0,04411604 ! receptor metabolic process GO:0043112 46 25 0,000 0,03269281 0,04409131 ! chromosome condensation GO:0030261 45 25 0,000 0,03269281 0,04406661 ! response to starvation GO:0042594 42 25 0,000 0,03269281 0,04404194 ! neural crest cell development GO:0014032 54 25 0,000 0,03269281 0,04401729 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03269281 0,04399268 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03269281 0,04396809 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03269281 0,04394352 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03269281 0,04391899 ! interaction with host GO:0051701 62 25 0,000 0,03269281 0,04389448 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03269281 0,04387 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03269281 0,04384554 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03269281 0,04382112 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03269281 0,04379672 ! immunoglobulin production GO:0002377 55 25 0,000 0,03269281 0,04377235 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03269281 0,043748 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03269281 0,04372368 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03269281 0,04369939 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03269281 0,04367513 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03269281 0,04365089 ! telomere organization GO:0032200 43 25 0,000 0,03269281 0,04362668 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03269281 0,0436025 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03269281 0,04357834 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03397861 0,04526719 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03397861 0,04524214 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03397861 0,04521711 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03397861 0,04519212 ! initiation of viral infection GO:0019059 57 26 0,000 0,03397861 0,04516715 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03397861 0,04514221 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03397861 0,0451173 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03397861 0,04509241 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03397861 0,04506755 ! molting cycle process GO:0022404 50 26 0,000 0,03397861 0,04504272 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03397861 0,04501792 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03397861 0,04499314 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03397861 0,04496839 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03397861 0,04494367 ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03397861 0,04491898 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03397861 0,04489431 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03397861 0,04486967 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03397861 0,04484506 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03397861 0,04482047 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03397861 0,04479591 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03397861 0,04477138 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03397861 0,04474687 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03397861 0,0447224 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03397861 0,04469794 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03397861 0,04467352 ! blastocyst development GO:0001824 49 26 0,000 0,03397861 0,04464912 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03397861 0,04462475 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03397861 0,0446004 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03397861 0,04457608 ! neuron fate commitment GO:0048663 48 27 0,000 0,03526274 0,04623551 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03526274 0,04621033 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03526274 0,04618517 ! iron ion transport GO:0006826 59 27 0,000 0,03526274 0,04616005 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03526274 0,04613495 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03526274 0,04610987 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03526274 0,04608483 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03526274 0,04605981 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03526274 0,04603482 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03526274 0,04600985 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03526274 0,04598491 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03526274 0,04596 ! autophagy GO:0006914 41 27 0,000 0,03526274 0,04593512 ! male gonad development GO:0008584 44 27 0,000 0,03526274 0,04591026 ! response to toxin GO:0009636 47 27 0,000 0,03526274 0,04588543 ! primary neural tube formation GO:0014020 51 27 0,000 0,03526274 0,04586063 ! base-excision repair GO:0006284 41 27 0,000 0,03526274 0,04583585 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03526274 0,0458111 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03526274 0,04578638 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03526274 0,04576169 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03526274 0,04573702 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03526274 0,04571237 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03526274 0,04568776 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03526274 0,04566317 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03526274 0,0456386 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03654521 0,047273 ! circadian rhythm GO:0007623 50 28 0,000 0,03654521 0,0472476 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03654521 0,04722223 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03654521 0,04719688 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03654521 0,04717156 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03654521 0,04714627 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03654521 0,047121 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03654521 0,04709576 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03654521 0,04707055 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03654521 0,04704536 ! synaptogenesis GO:0007416 42 28 0,000 0,03654521 0,04702021 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03654521 0,04699507 ! lipid oxidation GO:0034440 43 28 0,000 0,03654521 0,04696997 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03654521 0,04694489 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03654521 0,04691984 ! translational initiation GO:0006413 65 29 0,000 0,03782602 0,04853835 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03782602 0,04851248 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03782602 0,04848663 ! regulation of pH GO:0006885 43 29 0,000 0,03782602 0,04846081 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03782602 0,04843502 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03782602 0,04840926 ! catechol metabolic process GO:0009712 54 29 0,000 0,03782602 0,04838352 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03782602 0,04835781 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03782602 0,04833213 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03782602 0,04830648 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03782602 0,04828085 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03782602 0,04825525 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03782602 0,04822968 ! cell fate determination GO:0001709 60 29 0,000 0,03782602 0,04820413 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03782602 0,04817862 ! detection of light stimulus GO:0009583 38 29 0,000 0,03782602 0,04815312 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03782602 0,04812766 ! tissue homeostasis GO:0001894 48 29 0,000 0,03782602 0,04810222 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03782602 0,04807681 ! phenol metabolic process GO:0018958 55 30 0,000 0,03910517 0,04967636 ! zinc ion transport GO:0006829 45 30 0,000 0,03910517 0,04965015 ! membrane docking GO:0022406 61 30 0,000 0,03910517 0,04962396 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03910517 0,0495978 ! cell junction assembly GO:0034329 78 30 0,000 0,03910517 0,04957167 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03910517 0,04954557 ! acute-phase response GO:0006953 49 30 0,000 0,03910517 0,04951949 ! myofibril assembly GO:0030239 47 30 0,000 0,03910517 0,04949344 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03910517 0,04946742 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03910517 0,04944142 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03910517 0,04941546 ! phospholipid transport GO:0015914 51 30 0,000 0,03910517 0,04938952 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03910517 0,04936361 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03910517 0,04933772 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03910517 0,04931186 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03910517 0,04928603 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03910517 0,04926023 ! response to heat GO:0009408 50 30 0,000 0,03910517 0,04923445 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04038266 0,05081625 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04038266 0,05078969 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04038266 0,05076315 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04038266 0,05073664 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04038266 0,05071016 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04038266 0,05068371 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04038266 0,05065728 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04038266 0,05063089 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04038266 0,05060451 ! ovulation cycle process GO:0022602 49 31 0,000 0,04038266 0,05057817 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04038266 0,05055186 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04038266 0,05052557 ! peptide transport GO:0015833 55 31 0,000 0,04038266 0,05049931 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04038266 0,05047307 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04038266 0,05044687 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04038266 0,05042069 ! mesoderm formation GO:0001707 69 31 0,000 0,04038266 0,05039454 ! natural killer cell activation GO:0030101 45 31 0,000 0,04038266 0,05036841 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04038266 0,05034232 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04038266 0,05031624 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04038266 0,0502902 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04038266 0,05026418 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04038266 0,05023819 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04165849 0,05179862 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04165849 0,05177186 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04165849 0,05174513 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04165849 0,05171843 ! cholesterol transport GO:0030301 56 32 0,000 0,04165849 0,05169176 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04165849 0,05166511 ! spliceosome assembly GO:0000245 67 32 0,000 0,04165849 0,0516385 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04165849 0,05161191 ! metanephros development GO:0001656 74 32 0,000 0,04165849 0,05158534 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04165849 0,05155881 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04165849 0,0515323 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04165849 0,05150582 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04165849 0,05147936 ! muscle cell development GO:0055001 49 32 0,000 0,04165849 0,05145294 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04165849 0,05142654 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04165849 0,05140016 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04165849 0,05137382 ! ovulation cycle GO:0042698 51 32 0,000 0,04165849 0,0513475 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04165849 0,05132121 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04165849 0,05129494 ! hindbrain development GO:0030902 61 32 0,000 0,04165849 0,05126871 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04165849 0,0512425 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04165849 0,05121631 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04165849 0,05119015 ! gene silencing GO:0016458 65 32 0,000 0,04165849 0,05116402 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04293267 0,05270204 ! post-embryonic development GO:0009791 69 33 0,000 0,04293267 0,05267516 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04293267 0,05264832 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04293267 0,0526215 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04293267 0,0525947 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04293267 0,05256794 ! cell fate specification GO:0001708 52 33 0,000 0,04293267 0,0525412 ! sterol transport GO:0015918 57 33 0,000 0,04293267 0,05251449 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04293267 0,0524878 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04293267 0,05246115 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04293267 0,05243452 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04293267 0,05240791 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04293267 0,05238134 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04420519 0,05390659 ! glial cell differentiation GO:0010001 63 34 0,000 0,04420519 0,05387928 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04420519 0,053852 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04420519 0,05382474 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04420519 0,05379752 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04420519 0,05377032 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04420519 0,05374315 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04420519 0,05371601 ! mismatch repair GO:0006298 46 34 0,000 0,04420519 0,05368889 ! spermatid development GO:0007286 63 34 0,000 0,04420519 0,0536618 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04420519 0,05363474 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04420519 0,05360771 ! placenta development GO:0001890 53 34 0,000 0,04420519 0,0535807 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04420519 0,05355372 ! regulation of muscle development GO:0048634 70 35 0,000 0,04547607 0,05506564 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04547607 0,05503794 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04547607 0,05501027 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04547607 0,05498263 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04547607 0,05495501 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04547607 0,05492742 ! odontogenesis GO:0042476 66 35 0,000 0,04547607 0,05489986 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04547607 0,05487233 ! female gonad development GO:0008585 58 35 0,000 0,04547607 0,05484482 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04547607 0,05481735 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04547607 0,0547899 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04547607 0,05476247 ! cytokine production GO:0001816 59 35 0,000 0,04547607 0,05473508 ! neural tube formation GO:0001841 67 35 0,000 0,04547607 0,05470771 ! vesicle localization GO:0051648 64 35 0,000 0,04547607 0,05468037 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0467453 0,05617842 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0467453 0,05615037 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0467453 0,05612235 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0467453 0,05609436 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0467453 0,0560664 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0467453 0,05603846 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0467453 0,05601055 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0467453 0,05598267 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0467453 0,05595482 ! aerobic respiration GO:0009060 55 36 0,000 0,0467453 0,055927 ! embryonic organ development GO:0048568 57 36 0,000 0,0467453 0,0558992 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0467453 0,05587143 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04801288 0,05735799 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04801288 0,05732953 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04801288 0,05730109 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04801288 0,05727268 ! organic anion transport GO:0015711 68 37 0,000 0,04801288 0,0572443 ! tissue remodeling GO:0048771 76 37 0,000 0,04801288 0,05721595 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04801288 0,05718762 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04801288 0,05715933 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04801288 0,05713106 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04801288 0,05710282 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04801288 0,0570746 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04801288 0,05704642 ! glycogen metabolic process GO:0005977 61 37 0,000 0,04801288 0,05701826 ! pigment metabolic process GO:0042440 80 37 0,000 0,04801288 0,05699013 ! spermatid differentiation GO:0048515 66 37 0,000 0,04801288 0,05696203 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04801288 0,05693396 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04927882 0,05840633 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04927882 0,05837757 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04927882 0,05834884 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04927882 0,05832014 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04927882 0,05829147 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04927882 0,05826283 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04927882 0,05823421 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04927882 0,05820562 ! lipid homeostasis GO:0055088 67 38 0,000 0,04927882 0,05817706 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04927882 0,05814853 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04927882 0,05812002 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04927882 0,05809155 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04927882 0,0580631 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04927882 0,05803468 ! glucan metabolic process GO:0044042 62 38 0,000 0,04927882 0,05800629 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,05054312 0,0594654 ! mammary gland development GO:0030879 86 39 0,000 0,05054312 0,05943634 ! learning GO:0007612 77 39 0,000 0,05054312 0,0594073 ! ear morphogenesis GO:0042471 60 39 0,000 0,05054312 0,0593783 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05054312 0,05934932 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05054312 0,05932037 ! segmentation GO:0035282 67 39 0,000 0,05054312 0,05929144 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05054312 0,05926255 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05054312 0,05923368 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05054312 0,05920485 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05054312 0,05917604 ! RNA modification GO:0009451 57 39 0,000 0,05054312 0,05914725 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05054312 0,0591185 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05180578 0,06056594 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05180578 0,06053653 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05180578 0,06050714 ! feeding behavior GO:0007631 59 40 0,000 0,05180578 0,06047778 ! negative regulation of binding GO:0051100 72 40 0,000 0,05180578 0,06044845 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05180578 0,06041915 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05180578 0,06038988 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05180578 0,06036063 ! maintenance of protein location GO:0045185 91 40 0,000 0,05180578 0,06033142 ! cytokinesis GO:0000910 72 40 0,000 0,05180578 0,06030223 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,0530668 0,0617402 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,0530668 0,06171036 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,0530668 0,06168055 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,0530668 0,06165076 ! gliogenesis GO:0042063 88 41 0,000 0,0530668 0,06162101 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,0530668 0,06159128 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,0530668 0,06156159 ! T cell differentiation GO:0030217 81 41 0,000 0,0530668 0,06153192 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,0530668 0,06150228 ! female gamete generation GO:0007292 61 41 0,000 0,0530668 0,06147267 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,0530668 0,06144309 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05432619 0,062871 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05432619 0,06284078 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05432619 0,06281058 ! regulation of tube size GO:0035150 71 42 0,000 0,05432619 0,06278041 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05432619 0,06275027 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05432619 0,06272016 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,05432619 0,06269008 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05432619 0,06266003 ! neuron migration GO:0001764 79 42 0,000 0,05432619 0,06263 ! regulation of protein secretion GO:0050708 71 42 0,000 0,05432619 0,06260001 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05432619 0,06257004 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05558395 0,06398803 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05558395 0,06395742 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05558395 0,06392685 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05558395 0,06389631 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,05558395 0,06386579 ! glucose transport GO:0015758 65 43 0,000 0,05558395 0,06383531 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05558395 0,06380485 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05558395 0,06377443 ! neural tube development GO:0021915 77 43 0,000 0,05558395 0,06374403 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05558395 0,06371366 ! striated muscle contraction GO:0006941 77 43 0,000 0,05558395 0,06368332 ! phagocytosis GO:0006909 90 43 0,000 0,05558395 0,06365301 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05558395 0,06362273 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05684007 0,06502958 ! hexose transport GO:0008645 67 44 0,000 0,05684007 0,06499867 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05684007 0,06496779 ! male sex differentiation GO:0046661 76 44 0,000 0,05684007 0,06493694 ! biopolymer methylation GO:0043414 84 44 0,000 0,05684007 0,06490612 ! B cell differentiation GO:0030183 107 44 0,000 0,05684007 0,06487533 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05684007 0,06484457 ! developmental growth GO:0048589 82 44 0,000 0,05684007 0,06481384 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05684007 0,06478314 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,05809456 0,06618159 ! glycolysis GO:0006096 65 45 0,000 0,05809456 0,06615027 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,05809456 0,06611898 ! leukocyte migration GO:0050900 68 45 0,000 0,05809456 0,06608771 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05809456 0,06605648 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,05809456 0,06602528 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,05809456 0,06599411 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05809456 0,06596296 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,05809456 0,06593185 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05809456 0,06590076 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05809456 0,06586971 ! cell growth GO:0016049 84 45 0,000 0,05809456 0,06583868 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05934743 0,06722689 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,05934743 0,06719525 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05934743 0,06716365 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05934743 0,06713207 ! pigmentation GO:0043473 100 46 0,000 0,05934743 0,06710052 ! response to insulin stimulus GO:0032868 95 46 0,000 0,05934743 0,06706901 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,05934743 0,06703752 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06059867 0,06841877 ! endosome transport GO:0016197 108 47 0,000 0,06059867 0,06838668 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06059867 0,06835462 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06059867 0,06832259 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06059867 0,06829059 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06059867 0,06825862 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06059867 0,06822667 ! methylation GO:0032259 90 47 0,000 0,06059867 0,06819476 ! protein homooligomerization GO:0051260 76 47 0,000 0,06059867 0,06816288 ! mitochondrial transport GO:0006839 82 48 0,000 0,06184829 0,06953598 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06184829 0,0695035 ! cellular component disassembly GO:0022411 86 48 0,000 0,06184829 0,06947105 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06184829 0,06943863 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,06184829 0,06940624 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06184829 0,06937389 ! activation of caspase activity GO:0006919 84 48 0,000 0,06184829 0,06934156 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06184829 0,06930926 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06184829 0,069277 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06184829 0,06924476 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06309629 0,07060915 ! regulation of action potential GO:0001508 95 49 0,000 0,06309629 0,07057632 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06309629 0,07054353 ! regulation of ion transport GO:0043269 77 49 0,000 0,06309629 0,07051076 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06309629 0,07047803 ! peptide metabolic process GO:0006518 76 49 0,000 0,06309629 0,07044532 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06309629 0,07041265 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06309629 0,07038001 ! endocrine system development GO:0035270 104 49 0,000 0,06309629 0,07034739 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06309629 0,07031481 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06309629 0,07028226 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06309629 0,07024973 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,06434267 0,07160428 ! neuromuscular process GO:0050905 99 50 0,000 0,06434267 0,07157118 ! regulation of ossification GO:0030278 117 50 0,000 0,06434267 0,07153811 ! inner ear development GO:0048839 79 50 0,000 0,06434267 0,07150506 ! histone modification GO:0016570 91 50 0,000 0,06434267 0,07147205 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06434267 0,07143907 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06434267 0,07140612 ! positive regulation of binding GO:0051099 78 51 0,000 0,06558743 0,07275397 ! viral infectious cycle GO:0019058 99 51 0,000 0,06558743 0,07272044 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06558743 0,07268695 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06558743 0,07265348 ! excretion GO:0007588 83 51 0,000 0,06558743 0,07262005 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06558743 0,07258664 ! chromatin remodeling GO:0006338 109 51 0,000 0,06558743 0,07255327 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06558743 0,07251993 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06558743 0,07248662 ! regulation of cell shape GO:0008360 125 51 0,000 0,06558743 0,07245333 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06558743 0,07242008 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06683058 0,07375889 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06683058 0,07372507 ! membrane fusion GO:0006944 110 52 0,000 0,06683058 0,07369128 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06683058 0,07365753 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06683058 0,0736238 ! amino acid activation GO:0043038 92 52 0,000 0,06683058 0,0735901 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,06683058 0,07355644 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,06807212 0,07488867 ! RNA catabolic process GO:0006401 93 53 0,000 0,06807212 0,07485444 ! regulation of translational initiation GO:0006446 82 53 0,000 0,06807212 0,07482024 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06807212 0,07478608 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06807212 0,07475195 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,06807212 0,07471784 ! cell maturation GO:0048469 100 53 0,000 0,06807212 0,07468377 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,06807212 0,07464973 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,06807212 0,07461572 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06931204 0,07594024 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06931204 0,07590568 ! cell recognition GO:0008037 85 54 0,000 0,06931204 0,07587114 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06931204 0,07583664 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06931204 0,07580217 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06931204 0,07576773 ! chloride transport GO:0006821 90 55 0,000 0,07055036 0,07708636 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07055036 0,07705137 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,07055036 0,07701641 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,07055036 0,07698148 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07055036 0,07694658 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07055036 0,07691172 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,07055036 0,07687689 ! aging GO:0007568 103 55 0,000 0,07055036 0,07684208 ! gastrulation GO:0007369 112 55 0,000 0,07055036 0,07680731 ! heart morphogenesis GO:0003007 97 55 0,000 0,07055036 0,07677258 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,07055036 0,07673787 ! RNA elongation GO:0006354 79 55 0,000 0,07055036 0,07670319 ! nuclear export GO:0051168 97 55 0,000 0,07055036 0,07666855 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07055036 0,07663393 ! regulation of actin filament length GO:0030832 105 56 0,000 0,07178707 0,0779421 ! sensory perception of smell GO:0007608 80 56 0,000 0,07178707 0,07790694 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,07178707 0,07787182 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07178707 0,07783672 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07178707 0,07780166 ! regulation of DNA replication GO:0006275 101 56 0,000 0,07178707 0,07776663 ! proton transport GO:0015992 94 56 0,000 0,07178707 0,07773163 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,07178707 0,07769667 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,07302218 0,07899791 ! muscle fiber development GO:0048747 112 57 0,000 0,07302218 0,07896241 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,07302218 0,07892693 ! lipid modification GO:0030258 97 57 0,000 0,07302218 0,07889149 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,07302218 0,07885608 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,07302218 0,07882071 ! maintenance of location GO:0051235 118 57 0,000 0,07302218 0,07878536 ! hydrogen transport GO:0006818 97 58 0,000 0,07425568 0,08008031 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,07425568 0,08004443 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07425568 0,08000858 ! adult behavior GO:0030534 99 58 0,000 0,07425568 0,07997277 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07425568 0,07993699 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07548758 0,0812268 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07548758 0,08119049 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07548758 0,08115421 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,07548758 0,08111796 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07548758 0,08108175 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07548758 0,08104557 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07671789 0,08232972 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07671789 0,08229302 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07671789 0,08225634 ! camera-type eye development GO:0043010 116 60 0,000 0,07671789 0,0822197 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07671789 0,0821831 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07671789 0,08214652 ! kidney development GO:0001822 122 60 0,000 0,07671789 0,08210998 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07794659 0,08338795 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07794659 0,08335089 ! mesoderm development GO:0007498 119 61 0,000 0,07794659 0,08331386 ! tRNA processing GO:0008033 89 61 0,000 0,07794659 0,08327687 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07794659 0,08323991 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,07794659 0,08320298 ! ear development GO:0043583 103 62 0,000 0,07917371 0,08447536 ! viral reproductive process GO:0022415 126 62 0,000 0,07917371 0,08443792 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07917371 0,08440051 ! gonad development GO:0008406 98 62 0,000 0,07917371 0,08436313 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07917371 0,08432578 ! regulation of mitosis GO:0007088 105 63 0,000 0,08039923 0,08559316 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08039923 0,08555531 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08039923 0,08551748 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08162316 0,08678097 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08162316 0,08674264 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08162316 0,08670434 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08162316 0,08666607 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,08162316 0,08662785 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0828455 0,08788637 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0828455 0,08784763 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0828455 0,08780894 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0828455 0,08777027 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0828455 0,08773164 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08406626 0,08898523 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08406626 0,0889461 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08406626 0,088907 ! secondary metabolic process GO:0019748 116 66 0,000 0,08406626 0,08886794 ! developmental maturation GO:0021700 116 66 0,000 0,08406626 0,08882891 ! cell projection assembly GO:0030031 120 66 0,000 0,08406626 0,08878991 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08528543 0,09003807 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08528543 0,08999858 ! lung development GO:0030324 144 67 0,000 0,08528543 0,08995912 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08528543 0,0899197 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08528543 0,08988031 ! hexose catabolic process GO:0019320 104 67 0,000 0,08528543 0,08984096 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,08528543 0,08980164 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08528543 0,08976236 ! adaptive immune response GO:0002250 119 67 0,000 0,08528543 0,08972311 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08528543 0,0896839 ! amino acid transport GO:0006865 125 68 0,000 0,08650302 0,09092454 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,08650302 0,09088484 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08650302 0,09084517 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,08650302 0,09080553 ! regulation of lipase activity GO:0060191 130 68 0,000 0,08650302 0,09076593 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08650302 0,09072636 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08771903 0,09196165 ! urogenital system development GO:0001655 137 69 0,000 0,08771903 0,0919216 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08771903 0,09188158 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08771903 0,0918416 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08771903 0,09180165 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08893346 0,09303214 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08893346 0,09299171 ! amine catabolic process GO:0009310 117 71 0,000 0,09014632 0,09421896 ! reproductive structure development GO:0048608 113 71 0,000 0,09014632 0,09417805 ! appendage development GO:0048736 136 71 0,000 0,09014632 0,09413717 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,09014632 0,09409633 ! B cell activation GO:0042113 160 71 0,000 0,09014632 0,09405553 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,09014632 0,09401476 ! regulation of immune effector process GO:0002697 137 71 0,000 0,09014632 0,09397402 ! acute inflammatory response GO:0002526 113 72 0,000 0,0913576 0,09519549 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0913576 0,09515428 ! carbohydrate transport GO:0008643 110 72 0,000 0,0913576 0,09511311 ! respiratory system development GO:0060541 153 72 0,000 0,0913576 0,09507197 ! learning or memory GO:0007611 147 73 0,000 0,09256731 0,09628921 ! regulation of blood pressure GO:0008217 125 73 0,000 0,09256731 0,0962476 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,09256731 0,09620602 ! axon guidance GO:0007411 139 73 0,000 0,09256731 0,09616448 ! fertilization GO:0009566 90 73 0,000 0,09256731 0,09612298 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,09377545 0,09733552 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,09377545 0,09729354 ! neurotransmitter transport GO:0006836 123 74 0,000 0,09377545 0,09725161 ! exocytosis GO:0006887 133 74 0,000 0,09377545 0,09720971 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,09377545 0,09716784 ! organelle localization GO:0051640 136 74 0,000 0,09377545 0,09712601 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,09498202 0,09833336 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,09498202 0,09829107 ! rhythmic process GO:0048511 128 75 0,000 0,09498202 0,09824881 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,09498202 0,09820659 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09618702 0,09940978 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09618702 0,0993671 ! defense response to bacterium GO:0042742 89 76 0,000 0,09618702 0,09932445 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,09618702 0,09928184 ! regulation of catabolic process GO:0009894 161 76 0,000 0,09618702 0,09923927 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,09739046 0,10043783 ! blood coagulation GO:0007596 146 78 0,000 0,09859234 0,10163375 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,09859234 0,10159022 ! protein oligomerization GO:0051259 139 78 0,000 0,09859234 0,10154673 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09979265 0,10273904 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09979265 0,10269509 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,09979265 0,10265119 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09979265 0,10260732 ! muscle cell differentiation GO:0042692 159 80 0,000 0,10099141 0,10379553 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,10099141 0,10375121 ! protein import into nucleus GO:0006606 158 80 0,000 0,10099141 0,10370693 ! inorganic anion transport GO:0015698 138 80 0,000 0,10099141 0,10366269 ! T cell activation GO:0042110 168 81 0,000 0,10218861 0,10484682 ! response to hypoxia GO:0001666 171 81 0,000 0,10218861 0,10480213 ! digestion GO:0007586 112 81 0,000 0,10218861 0,10475748 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,10218861 0,10471286 ! nuclear import GO:0051170 161 81 0,000 0,10218861 0,10466829 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,10218861 0,10462375 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,10338426 0,10580286 ! response to drug GO:0042493 143 82 0,000 0,10338426 0,10575788 ! response to nutrient GO:0007584 125 82 0,000 0,10338426 0,10571293 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,10338426 0,10566803 ! response to oxygen levels GO:0070482 176 83 0,000 0,10457836 0,10684311 ! hemostasis GO:0007599 158 84 0,000 0,1057709 0,10801561 ! negative regulation of transport GO:0051051 153 84 0,000 0,1057709 0,10796979 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1057709 0,107924 ! nucleosome assembly GO:0006334 122 85 0,000 0,10696189 0,10909297 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10696189 0,10904675 ! amine biosynthetic process GO:0009309 138 86 0,000 0,10815134 0,11021268 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,10815134 0,11016602 ! chromatin assembly GO:0031497 124 86 0,000 0,10815134 0,1101194 ! tube morphogenesis GO:0035239 176 86 0,000 0,10815134 0,11007281 ! amine transport GO:0015837 155 86 0,000 0,10815134 0,11002627 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10933925 0,11118776 ! protein localization in nucleus GO:0034504 176 87 0,000 0,10933925 0,11114078 ! regulation of protein transport GO:0051223 154 87 0,000 0,10933925 0,11109385 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,11052561 0,11225184 ! regulation of DNA binding GO:0051101 155 88 0,000 0,11052561 0,11220448 ! gland development GO:0048732 206 88 0,000 0,11052561 0,11215716 ! regulation of neurological system process GO:0031644 148 88 0,000 0,11052561 0,11210987 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,11052561 0,11206263 ! cellular defense response GO:0006968 114 89 0,000 0,11171043 0,11321621 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,11171043 0,11316854 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,11171043 0,11312091 ! sex differentiation GO:0007548 145 90 0,000 0,11289371 0,11427104 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11289371 0,11422299 ! sterol metabolic process GO:0016125 152 91 0,000 0,11407546 0,11537013 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11407546 0,11532166 ! regulation of defense response GO:0031347 149 92 0,000 0,11525567 0,11646583 ! nucleosome organization GO:0034728 138 92 0,000 0,11525567 0,11641693 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,11525567 0,11636808 ! vitamin metabolic process GO:0006766 139 92 0,000 0,11525567 0,11631927 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,11643434 0,11745955 ! regulation of membrane potential GO:0042391 164 93 0,000 0,11643434 0,11741032 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,11643434 0,11736113 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,11761149 0,11849801 ! female pregnancy GO:0007565 164 94 0,000 0,11761149 0,11844841 ! transcription initiation GO:0006352 153 94 0,000 0,11761149 0,11839885 ! regulation of T cell activation GO:0050863 158 94 0,000 0,11761149 0,11834933 ! forebrain development GO:0030900 188 95 0,000 0,11878711 0,11948235 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,11878711 0,11943242 ! leukocyte differentiation GO:0002521 202 96 0,000 0,11996119 0,1205625 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11996119 0,12051216 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,11996119 0,12046187 ! positive regulation of immune response GO:0050778 156 96 0,000 0,11996119 0,12041161 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,12113376 0,12153787 ! protein ubiquitination GO:0016567 217 97 0,000 0,12113376 0,12148721 ! hormone metabolic process GO:0042445 157 97 0,000 0,12113376 0,12143659 ! regulation of protein localization GO:0032880 176 97 0,000 0,12113376 0,12138602 ! response to virus GO:0009615 160 98 0,000 0,1223048 0,12250847 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1223048 0,12245749 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1223048 0,12240655 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12347432 0,12352566 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,12347432 0,12347432 GO:0060538|skeletal muscle organ development,