pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5599-7-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 3,000 2,898E-09 1,057E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 4,000 7,73E-09 1,41E-05 ! protein kinase regulator activity GO:0019887 74 66 4,000 2,9E-08 3,526E-05 ! kinase regulator activity GO:0019207 93 76 4,000 5,939E-08 5,416E-05 ! microtubule cytoskeleton organization GO:0000226 113 87 4,000 1,176E-07 8,577E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 1,326E-07 8,061E-05 ! induction of apoptosis by intracellular signals GO:0008629 56 41 3,000 2,858E-07 1,49E-04 ! response to UV GO:0009411 59 45 3,000 4,19E-07 1,911E-04 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 2,000 1,316E-06 5,334E-04 ! G2/M transition of mitotic cell cycle GO:0000086 22 16 2,000 1,316E-06 4,801E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 2,000 3,599E-06 1,194E-03 ! interphase of mitotic cell cycle GO:0051329 100 81 3,000 4,523E-06 1,375E-03 ! interphase GO:0051325 103 83 3,000 4,986E-06 1,399E-03 ! spindle organization GO:0007051 38 27 2,000 6,804E-06 1,773E-03 ! response to light stimulus GO:0009416 131 100 3,000 1,047E-05 2,546E-03 ! microtubule organizing center part GO:0044450 46 32 2,000 1,149E-05 2,619E-03 ! protein kinase inhibitor activity GO:0004860 37 34 2,000 1,383E-05 2,968E-03 ! kinase inhibitor activity GO:0019210 47 35 2,000 1,511E-05 3,063E-03 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 1,000 1,85E-05 3,552E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 1,000 1,85E-05 3,375E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! Golgi to plasma membrane transport GO:0006893 7 5 1,000 1,85E-05 3,214E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,85E-05 3,068E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 2,773E-05 4,398E-03 ! SAP kinase activity GO:0016909 7 6 1,000 2,773E-05 4,215E-03 ! natural killer cell mediated immunity GO:0002228 7 6 1,000 2,773E-05 4,046E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! G1/S transition of mitotic cell cycle GO:0000082 54 43 2,000 2,829E-05 3,969E-03 ! centriolar satellite GO:0034451 10 7 1,000 3,879E-05 5,241E-03 ! regulation of DNA repair GO:0006282 19 7 1,000 3,879E-05 5,053E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 1,000 3,879E-05 4,879E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 1,000 3,879E-05 4,717E-03 ! DNA damage response, signal transduction GO:0042770 84 50 2,000 4,464E-05 5,253E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 1,000 5,167E-05 5,891E-03 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 1,000 5,167E-05 5,712E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 5,167E-05 5,544E-03 ! microtubule bundle formation GO:0001578 8 8 1,000 5,167E-05 5,386E-03 ! leukocyte mediated cytotoxicity GO:0001909 10 8 1,000 5,167E-05 5,236E-03 ! positive regulation of protein ubiquitination GO:0031398 17 8 1,000 5,167E-05 5,095E-03 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 1,000 5,167E-05 4,961E-03 ! postreplication repair GO:0006301 19 8 1,000 5,167E-05 4,833E-03 ! gamma-tubulin binding GO:0043015 8 8 1,000 5,167E-05 4,712E-03 ! establishment of cell polarity GO:0030010 10 9 1,000 6,638E-05 5,906E-03 ! gamma-tubulin complex GO:0000930 19 9 1,000 6,638E-05 5,765E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 1,000 6,638E-05 5,631E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 8,29E-05 6,873E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 8,29E-05 6,721E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 2,000 8,519E-05 6,756E-03 ! negative regulation of protein kinase activity GO:0006469 78 64 2,000 9,368E-05 7,271E-03 ! negative regulation of kinase activity GO:0033673 79 65 2,000 9,812E-05 7,457E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 2,000 9,812E-05 7,305E-03 ! cell killing GO:0001906 13 11 1,000 1,012E-04 7,386E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 1,012E-04 7,242E-03 ! Golgi vesicle budding GO:0048194 12 11 1,000 1,012E-04 7,102E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 1,012E-04 6,968E-03 ! tubulin binding GO:0015631 92 66 2,000 1,027E-04 6,938E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 2,000 1,074E-04 7,124E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 2,000 1,123E-04 7,313E-03 ! midbody GO:0030496 14 12 1,000 1,214E-04 7,768E-03 ! positive regulation of ligase activity GO:0051351 86 70 2,000 1,224E-04 7,698E-03 ! negative regulation of transferase activity GO:0051348 85 70 2,000 1,224E-04 7,568E-03 ! eye photoreceptor cell differentiation GO:0001754 17 13 1,000 1,433E-04 8,714E-03 GO:0042462|eye photoreceptor cell development, ! MHC class I protein binding GO:0042288 23 13 1,000 1,433E-04 8,572E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 2,000 1,503E-04 8,843E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,671E-04 9,674E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 1,671E-04 9,523E-03 ! release of cytochrome c from mitochondria GO:0001836 26 14 1,000 1,671E-04 9,377E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 1,671E-04 9,235E-03 ! MAP kinase activity GO:0004707 16 14 1,000 1,671E-04 9,097E-03 ! positive regulation of protein modification process GO:0031401 100 78 2,000 1,689E-04 9,059E-03 ! regulation of ligase activity GO:0051340 95 78 2,000 1,689E-04 8,927E-03 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,926E-04 0,01003795 ! double-strand break repair via homologous recombination GO:0000724 36 15 1,000 1,926E-04 9,897E-03 GO:0000725|recombinational repair, ! protein kinase C activity GO:0004697 17 15 1,000 1,926E-04 9,759E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 2,000 2,03E-04 0,01014434 GO:0010498|proteasomal protein catabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 1,000 2,199E-04 0,01084256 ! photoreceptor cell development GO:0042461 22 16 1,000 2,199E-04 0,010698 GO:0046530|photoreceptor cell differentiation, ! centrosome cycle GO:0007098 26 16 1,000 2,199E-04 0,01055723 ! regulation of protein ubiquitination GO:0031396 27 16 1,000 2,199E-04 0,01042013 ! membrane budding GO:0006900 18 16 1,000 2,199E-04 0,01028654 ! Golgi vesicle transport GO:0048193 98 86 2,000 2,255E-04 0,01041213 ! skin development GO:0043588 20 17 1,000 2,491E-04 0,01135692 ! positive regulation of cell size GO:0045793 19 18 1,000 2,799E-04 0,01260802 ! spindle microtubule GO:0005876 27 18 1,000 2,799E-04 0,01245426 ! nuclear ubiquitin ligase complex GO:0000152 31 18 1,000 2,799E-04 0,01230421 ! MHC protein binding GO:0042287 30 18 1,000 2,799E-04 0,01215773 ! activation of pro-apoptotic gene products GO:0008633 26 19 1,000 3,126E-04 0,01341673 ! cellular response to unfolded protein GO:0034620 21 19 1,000 3,126E-04 0,01326072 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 3,126E-04 0,0131083 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 1,000 3,126E-04 0,01295934 ! negative regulation of lipid metabolic process GO:0045833 34 20 1,000 3,471E-04 0,01422532 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 1,000 3,471E-04 0,01406726 ! apoptotic mitochondrial changes GO:0008637 33 21 1,000 3,833E-04 0,01536404 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 3,833E-04 0,01519704 ! ubiquitin binding GO:0043130 25 21 1,000 3,833E-04 0,01503363 ! cell-cell junction organization GO:0045216 24 21 1,000 3,833E-04 0,0148737 ! caveola GO:0005901 25 21 1,000 3,833E-04 0,01471713 ! microtubule organizing center organization GO:0031023 33 22 1,000 4,212E-04 0,01600654 GO:0051297|centrosome organization, ! positive regulation of B cell activation GO:0050871 26 22 1,000 4,212E-04 0,01584152 ! androgen receptor binding GO:0050681 34 24 1,000 5,024E-04 0,01870242 ! small conjugating protein binding GO:0032182 29 24 1,000 5,024E-04 0,01851351 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 1,000 5,024E-04 0,01832837 ! site of polarized growth GO:0030427 28 25 1,000 5,456E-04 0,01970806 ! regulation of lipid biosynthetic process GO:0046890 35 25 1,000 5,456E-04 0,01951485 ! GABA receptor activity GO:0016917 31 26 1,000 5,906E-04 0,02091796 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 5,906E-04 0,02071683 ! response to endoplasmic reticulum stress GO:0034976 30 26 1,000 5,906E-04 0,02051952 ! fat cell differentiation GO:0045444 30 27 1,000 6,373E-04 0,02193328 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 6,373E-04 0,0217283 ! regulation of fatty acid metabolic process GO:0019217 41 28 1,000 6,858E-04 0,02316326 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 6,858E-04 0,02295075 ! ER-nuclear signaling pathway GO:0006984 32 29 1,000 7,359E-04 0,02440587 ! establishment or maintenance of cell polarity GO:0007163 34 29 1,000 7,359E-04 0,024186 ! glutamate receptor activity GO:0008066 35 30 1,000 7,878E-04 0,02566028 ! regulation of microtubule-based process GO:0032886 41 30 1,000 7,878E-04 0,0254332 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 8,414E-04 0,02692574 GO:0045936|negative regulation of phosphate metabolic process, ! protein targeting to membrane GO:0006612 35 31 1,000 8,414E-04 0,0266916 ! response to calcium ion GO:0051592 34 31 1,000 8,414E-04 0,0264615 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 1,000 8,968E-04 0,02796048 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! meiosis I GO:0007127 53 32 1,000 8,968E-04 0,02772353 ! regulation of cellular ketone metabolic process GO:0010565 46 33 1,000 9,538E-04 0,02923918 ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 9,538E-04 0,02899552 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 1,013E-03 0,03052707 ! regulation of B cell activation GO:0050864 40 34 1,000 1,013E-03 0,03027685 ! protein polymerization GO:0051258 38 34 1,000 1,013E-03 0,03003069 ! steroid hormone receptor binding GO:0035258 44 34 1,000 1,013E-03 0,02978851 ! positive regulation of DNA metabolic process GO:0051054 53 35 1,000 1,073E-03 0,03131439 ! response to estrogen stimulus GO:0043627 48 35 1,000 1,073E-03 0,03106586 ! androgen receptor signaling pathway GO:0030521 47 35 1,000 1,073E-03 0,03082125 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 1,135E-03 0,03235169 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 1,135E-03 0,03210091 GO:0050671|positive regulation of lymphocyte proliferation, ! cell junction organization GO:0034330 44 37 1,000 1,199E-03 0,03364548 ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 1,199E-03 0,03338865 GO:0032946|positive regulation of mononuclear cell proliferation, ! double-strand break repair GO:0006302 70 39 1,000 1,332E-03 0,03680435 ! damaged DNA binding GO:0003684 51 40 1,000 1,401E-03 0,03841735 ! keratin filament GO:0045095 44 41 1,000 1,471E-03 0,04005189 ! positive regulation of cell cycle GO:0045787 56 43 1,000 1,617E-03 0,0437046 ! positive regulation of growth GO:0045927 47 43 1,000 1,617E-03 0,04338325 ! eye morphogenesis GO:0048592 57 46 1,000 1,849E-03 0,04923591 ! JNK cascade GO:0007254 48 46 1,000 1,849E-03 0,04887913 ! microtubule binding GO:0008017 61 47 1,000 1,93E-03 0,05064106 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 1,000 2,012E-03 0,05242069 ! cell cortex part GO:0044448 54 48 1,000 2,012E-03 0,05204891 ! regulation of gene expression, epigenetic GO:0040029 64 49 1,000 2,096E-03 0,05383571 ! negative regulation of cytoskeleton organization GO:0051494 73 49 1,000 2,096E-03 0,05345923 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 2,096E-03 0,05308799 ! cytokine-mediated signaling pathway GO:0019221 56 50 1,000 2,181E-03 0,05487181 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 2,357E-03 0,05888864 ! vesicle organization GO:0016050 59 52 1,000 2,357E-03 0,05848804 ! keratinocyte differentiation GO:0030216 60 53 1,000 2,447E-03 0,06031957 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 2,447E-03 0,05991474 GO:0032944|regulation of mononuclear cell proliferation, ! steroid hormone receptor signaling pathway GO:0030518 70 55 1,000 2,633E-03 0,06402738 ! chromosome segregation GO:0007059 92 57 1,000 2,825E-03 0,06824116 ! diacylglycerol binding GO:0019992 65 57 1,000 2,825E-03 0,06779221 ! epidermal cell differentiation GO:0009913 66 58 1,000 2,923E-03 0,06969504 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 1,000 2,923E-03 0,06924248 ! lymphocyte mediated immunity GO:0002449 65 58 1,000 2,923E-03 0,06879575 ! actin filament organization GO:0007015 65 59 1,000 3,023E-03 0,07069292 ! response to steroid hormone stimulus GO:0048545 74 59 1,000 3,023E-03 0,07024265 ! regulation of cellular response to stress GO:0080135 79 59 1,000 3,023E-03 0,06979807 ! response to metal ion GO:0010038 65 60 1,000 3,125E-03 0,07168969 ! regulation of caspase activity GO:0043281 78 60 1,000 3,125E-03 0,07124163 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 1,000 3,333E-03 0,07551033 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 1,000 3,333E-03 0,07504422 ! negative regulation of cell growth GO:0030308 69 63 1,000 3,439E-03 0,07696362 ! regulation of endopeptidase activity GO:0052548 81 63 1,000 3,439E-03 0,07649433 ! response to unfolded protein GO:0006986 66 64 1,000 3,547E-03 0,07841652 ! nuclear hormone receptor binding GO:0035257 79 64 1,000 3,547E-03 0,07794413 ! negative regulation of cell size GO:0045792 71 65 1,000 3,656E-03 0,07986896 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 3,656E-03 0,07939355 ! response to inorganic substance GO:0010035 71 65 1,000 3,656E-03 0,07892377 ! leukocyte mediated immunity GO:0002443 73 66 1,000 3,767E-03 0,0808425 ! regulation of peptidase activity GO:0052547 86 67 1,000 3,88E-03 0,08277215 ! regulation of adenylate cyclase activity GO:0045761 81 68 1,000 3,994E-03 0,08471243 ! negative regulation of organelle organization GO:0010639 93 68 1,000 3,994E-03 0,08422276 ! regulation of cyclase activity GO:0031279 83 70 1,000 4,227E-03 0,08862379 ! hormone receptor binding GO:0051427 85 70 1,000 4,227E-03 0,08811737 ! positive regulation of phosphorylation GO:0042327 82 70 1,000 4,227E-03 0,0876167 ! response to protein stimulus GO:0051789 73 70 1,000 4,227E-03 0,08712169 ! cell cortex GO:0005938 77 70 1,000 4,227E-03 0,08663224 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 1,000 4,466E-03 0,09102296 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lyase activity GO:0051339 85 72 1,000 4,466E-03 0,09051727 ! membrane raft GO:0045121 81 72 1,000 4,466E-03 0,09001718 ! structural constituent of cytoskeleton GO:0005200 78 72 1,000 4,466E-03 0,08952258 ! regulation of cAMP biosynthetic process GO:0030817 86 73 1,000 4,588E-03 0,09146349 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 4,588E-03 0,09096641 ! cell-matrix adhesion GO:0007160 102 74 1,000 4,712E-03 0,09290878 ! phosphoinositide-mediated signaling GO:0048015 92 74 1,000 4,712E-03 0,09240927 ! ubiquitin ligase complex GO:0000151 91 74 1,000 4,712E-03 0,0919151 ! regulation of cell cycle process GO:0010564 113 75 1,000 4,837E-03 0,09385112 ! positive regulation of cell activation GO:0050867 94 75 1,000 4,837E-03 0,09335456 ! regulation of cAMP metabolic process GO:0030814 88 75 1,000 4,837E-03 0,09286322 ! meiosis GO:0007126 108 75 1,000 4,837E-03 0,09237702 GO:0051327|M phase of meiotic cell cycle, ! neuropeptide signaling pathway GO:0007218 85 76 1,000 4,963E-03 0,09429929 ! negative regulation of growth GO:0045926 85 76 1,000 4,963E-03 0,09381069 ! regulation of lipid metabolic process GO:0019216 98 76 1,000 4,963E-03 0,09332713 ! meiotic cell cycle GO:0051321 109 76 1,000 4,963E-03 0,09284853 ! condensed chromosome GO:0000793 106 76 1,000 4,963E-03 0,09237482 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 1,000 5,221E-03 0,09667516 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! eye development GO:0001654 93 80 1,000 5,484E-03 0,10104359 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 1,000 5,484E-03 0,10053584 ! cell-substrate adhesion GO:0031589 109 80 1,000 5,484E-03 0,10003316 ! mitochondrion organization GO:0007005 104 82 1,000 5,754E-03 0,10442895 ! microtubule-based movement GO:0007018 119 83 1,000 5,891E-03 0,10638718 ! regulation of nucleotide metabolic process GO:0006140 96 83 1,000 5,891E-03 0,10586311 ! regulation of DNA metabolic process GO:0051052 139 84 1,000 6,03E-03 0,10782181 ! DNA recombination GO:0006310 147 84 1,000 6,03E-03 0,10729585 ! pigment granule GO:0048770 101 87 1,000 6,454E-03 0,11429363 GO:0042470|melanosome, ! protein kinase binding GO:0019901 115 89 1,000 6,745E-03 0,11885992 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 6,926E-03 0,12146996 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 6,926E-03 0,12088877 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 6,926E-03 0,12031311 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 6,926E-03 0,1197429 ! response to superoxide GO:0000303 5 5 0,000 6,926E-03 0,11917808 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 6,926E-03 0,11861856 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 6,926E-03 0,11806426 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 6,926E-03 0,11751513 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 6,926E-03 0,11697108 ! quinolinate metabolic process GO:0046874 5 5 0,000 6,926E-03 0,11643204 ! biotin binding GO:0009374 7 5 0,000 6,926E-03 0,11589795 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 6,926E-03 0,11536873 ! tongue development GO:0043586 6 5 0,000 6,926E-03 0,11484433 ! nose development GO:0043584 5 5 0,000 6,926E-03 0,11432467 ! cell proliferation in forebrain GO:0021846 5 5 0,000 6,926E-03 0,1138097 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 6,926E-03 0,11329934 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 6,926E-03 0,11279354 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 6,926E-03 0,11229223 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 6,926E-03 0,11179537 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 6,926E-03 0,11130287 ! glycolipid transport GO:0046836 6 5 0,000 6,926E-03 0,1108147 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 6,926E-03 0,1103308 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 6,926E-03 0,1098511 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 6,926E-03 0,10937555 ! neuron adhesion GO:0007158 5 5 0,000 6,926E-03 0,10890411 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 6,926E-03 0,10843671 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 6,926E-03 0,1079733 ! opioid peptide activity GO:0001515 6 5 0,000 6,926E-03 0,10751384 ! selenocysteine incorporation GO:0001514 5 5 0,000 6,926E-03 0,10705827 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 6,926E-03 0,10660655 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 6,926E-03 0,10615862 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 6,926E-03 0,10571445 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 6,926E-03 0,10527397 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 6,926E-03 0,10483715 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,926E-03 0,10440394 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 6,926E-03 0,10397429 ! clathrin coat assembly GO:0048268 6 5 0,000 6,926E-03 0,10354817 ! cerebral cortex cell migration GO:0021795 5 5 0,000 6,926E-03 0,10312552 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 6,926E-03 0,10270631 ! membrane hyperpolarization GO:0060081 5 5 0,000 6,926E-03 0,1022905 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 6,926E-03 0,10187803 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 6,926E-03 0,10146889 ! translation repressor activity GO:0030371 8 5 0,000 6,926E-03 0,10106301 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 6,926E-03 0,10066037 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 6,926E-03 0,10026092 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 6,926E-03 0,09986463 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 6,926E-03 0,09947147 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 6,926E-03 0,09908138 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 6,926E-03 0,09869435 ! negative regulation of heart contraction GO:0045822 5 5 0,000 6,926E-03 0,09831032 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 6,926E-03 0,09792927 ! microfibril GO:0001527 5 5 0,000 6,926E-03 0,09755117 ! troponin I binding GO:0031013 5 5 0,000 6,926E-03 0,09717597 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 6,926E-03 0,09680365 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 6,926E-03 0,09643417 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 6,926E-03 0,0960675 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 6,926E-03 0,09570361 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 6,926E-03 0,09534246 ! protein lipoylation GO:0009249 14 5 0,000 6,926E-03 0,09498403 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,926E-03 0,09462829 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 6,926E-03 0,0942752 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 6,926E-03 0,09392473 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 6,926E-03 0,09357686 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 6,926E-03 0,09323156 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 6,926E-03 0,0928888 ! glutamate catabolic process GO:0006538 6 5 0,000 6,926E-03 0,09254854 ! microvillus organization GO:0032528 5 5 0,000 6,926E-03 0,09221078 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 6,926E-03 0,09187546 ! tyrosine catabolic process GO:0006572 5 5 0,000 6,926E-03 0,09154258 ! response to pH GO:0009268 5 5 0,000 6,926E-03 0,0912121 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 6,926E-03 0,090884 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 6,926E-03 0,09055825 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 6,926E-03 0,09023483 ! polyol biosynthetic process GO:0046173 5 5 0,000 6,926E-03 0,08991371 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 6,926E-03 0,08959487 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,926E-03 0,08927828 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 6,926E-03 0,08896392 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 6,926E-03 0,08865176 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 6,926E-03 0,08834179 ! anaerobic glycolysis GO:0019642 5 5 0,000 6,926E-03 0,08803398 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 6,926E-03 0,08772831 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 6,926E-03 0,08742475 ! peroxisomal matrix GO:0005782 5 5 0,000 6,926E-03 0,08712328 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 6,926E-03 0,08682389 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 6,926E-03 0,08652655 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 6,926E-03 0,08623124 ! multivesicular body GO:0005771 5 5 0,000 6,926E-03 0,08593793 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 6,926E-03 0,08564662 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 6,926E-03 0,08535727 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 6,926E-03 0,08506987 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 6,926E-03 0,0847844 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 6,926E-03 0,08450084 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 6,926E-03 0,08421918 ! epithelial cell maturation GO:0002070 14 5 0,000 6,926E-03 0,08393938 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 6,926E-03 0,08366143 ! muscle thin filament assembly GO:0030240 5 5 0,000 6,926E-03 0,08338532 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 6,926E-03 0,08311103 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 6,926E-03 0,08283853 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 6,926E-03 0,08256782 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,926E-03 0,08229887 ! positive regulation of translational initiation GO:0045948 6 5 0,000 6,926E-03 0,08203166 ! nonhomologous end joining complex GO:0070419 6 5 0,000 6,926E-03 0,08176619 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 6,926E-03 0,08150243 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 6,926E-03 0,08124036 ! ATPase activator activity GO:0001671 5 5 0,000 6,926E-03 0,08097998 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 6,926E-03 0,08072125 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 6,926E-03 0,08046418 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 6,926E-03 0,08020874 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 6,926E-03 0,07995491 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 6,926E-03 0,07970269 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 6,926E-03 0,07945205 ! cardiac myofibril assembly GO:0055003 5 5 0,000 6,926E-03 0,07920299 ! anterograde axon cargo transport GO:0008089 6 5 0,000 6,926E-03 0,07895548 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,926E-03 0,07870951 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 6,926E-03 0,07846507 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 6,926E-03 0,07822214 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 6,926E-03 0,07798072 ! protein localization to telomere GO:0070198 7 5 0,000 6,926E-03 0,07774078 ! response to exogenous dsRNA GO:0043330 5 5 0,000 6,926E-03 0,07750231 ! MutSalpha complex binding GO:0032407 7 5 0,000 6,926E-03 0,0772653 ! bile acid biosynthetic process GO:0006699 5 5 0,000 6,926E-03 0,07702973 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 6,926E-03 0,0767956 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 6,926E-03 0,07656289 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,926E-03 0,07633158 ! nerve growth factor binding GO:0048406 7 5 0,000 6,926E-03 0,07610166 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 6,926E-03 0,07587313 ! high-density lipoprotein binding GO:0008035 6 5 0,000 6,926E-03 0,07564597 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 6,926E-03 0,07542016 ! transcription initiation factor activity GO:0016986 5 5 0,000 6,926E-03 0,07519569 ! gas homeostasis GO:0033483 5 5 0,000 6,926E-03 0,07497256 ! Schwann cell development GO:0014044 5 5 0,000 6,926E-03 0,07475075 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 6,926E-03 0,07453024 ! cyclohydrolase activity GO:0019238 5 5 0,000 6,926E-03 0,07431104 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 6,926E-03 0,07409312 ! response to pheromone GO:0019236 5 5 0,000 6,926E-03 0,07387647 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 6,926E-03 0,07366109 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 6,926E-03 0,07344696 ! rhombomere development GO:0021546 6 5 0,000 6,926E-03 0,07323407 ! alanine transport GO:0032328 6 5 0,000 6,926E-03 0,07302241 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 6,926E-03 0,07281197 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 6,926E-03 0,07260274 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 6,926E-03 0,07239471 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 6,926E-03 0,07218786 ! regulation of meiosis GO:0040020 6 5 0,000 6,926E-03 0,0719822 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 6,926E-03 0,07177771 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 6,926E-03 0,07157437 ! lymphocyte costimulation GO:0031294 5 5 0,000 6,926E-03 0,07137218 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 6,926E-03 0,07117113 ! RS domain binding GO:0050733 6 5 0,000 6,926E-03 0,07097122 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 6,926E-03 0,07077242 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 6,926E-03 0,07057473 ! B cell homeostasis GO:0001782 6 5 0,000 6,926E-03 0,07037814 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 6,926E-03 0,07018265 ! anaphase GO:0051322 7 5 0,000 6,926E-03 0,06998823 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 6,926E-03 0,0697949 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 6,926E-03 0,06960262 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 6,926E-03 0,06941141 ! AP-2 adaptor complex GO:0030122 5 5 0,000 6,926E-03 0,06922124 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 6,926E-03 0,06903211 ! diuresis GO:0030146 5 5 0,000 6,926E-03 0,06884401 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 6,926E-03 0,06865694 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 6,926E-03 0,06847087 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 6,926E-03 0,06828582 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 6,926E-03 0,06810176 ! GTP-Rho binding GO:0017049 5 5 0,000 6,926E-03 0,06791869 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 6,926E-03 0,0677366 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,926E-03 0,06755549 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 6,926E-03 0,06737534 ! brown fat cell differentiation GO:0050873 5 5 0,000 6,926E-03 0,06719615 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,926E-03 0,06701791 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 6,926E-03 0,06684062 ! TAP complex GO:0042825 5 5 0,000 6,926E-03 0,06666425 ! platelet dense granule GO:0042827 6 5 0,000 6,926E-03 0,06648882 ! bHLH transcription factor binding GO:0043425 5 5 0,000 6,926E-03 0,06631431 ! secretory granule organization GO:0033363 5 5 0,000 6,926E-03 0,06614071 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 6,926E-03 0,06596802 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 6,926E-03 0,06579623 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 6,926E-03 0,06562533 ! lamin binding GO:0005521 8 5 0,000 6,926E-03 0,06545532 ! aldehyde-lyase activity GO:0016832 6 5 0,000 6,926E-03 0,06528618 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,926E-03 0,06511792 ! neural plate morphogenesis GO:0001839 6 5 0,000 6,926E-03 0,06495052 ! cyclosporin A binding GO:0016018 6 5 0,000 6,926E-03 0,06478398 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 6,926E-03 0,06461829 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 6,926E-03 0,06445345 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 6,926E-03 0,06428945 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 6,926E-03 0,06412628 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 6,926E-03 0,06396393 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 6,926E-03 0,06380241 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 6,926E-03 0,06364169 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 6,926E-03 0,06348179 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 6,926E-03 0,06332269 ! organ or tissue specific immune response GO:0002251 6 5 0,000 6,926E-03 0,06316438 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 6,926E-03 0,06300686 ! retina homeostasis GO:0001895 5 5 0,000 6,926E-03 0,06285013 ! prepulse inhibition GO:0060134 8 5 0,000 6,926E-03 0,06269418 ! maternal placenta development GO:0001893 5 5 0,000 6,926E-03 0,06253899 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 6,926E-03 0,06238457 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 6,926E-03 0,06223092 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 6,926E-03 0,06207802 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 6,926E-03 0,06192586 ! protein palmitoylation GO:0018345 5 5 0,000 6,926E-03 0,06177446 ! protein amino acid prenylation GO:0018346 6 5 0,000 6,926E-03 0,06162379 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 6,926E-03 0,06147385 ! stem cell division GO:0017145 6 5 0,000 6,926E-03 0,06132464 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 6,926E-03 0,06117616 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 6,926E-03 0,06102839 ! organ regeneration GO:0031100 6 5 0,000 6,926E-03 0,06088133 ! lymphocyte apoptosis GO:0070227 6 5 0,000 6,926E-03 0,06073498 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 6,926E-03 0,06058933 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 6,926E-03 0,06044438 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 6,926E-03 0,06030013 ! acyl carrier activity GO:0000036 5 5 0,000 6,926E-03 0,06015655 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 6,926E-03 0,06001366 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 6,926E-03 0,05987145 ! phagocytic vesicle GO:0045335 5 5 0,000 6,926E-03 0,05972991 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 6,926E-03 0,05958904 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 6,926E-03 0,05944883 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 6,926E-03 0,05930928 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 6,926E-03 0,05917038 ! polyol transport GO:0015791 8 5 0,000 6,926E-03 0,05903213 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 6,926E-03 0,05889453 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 6,926E-03 0,05875756 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 6,926E-03 0,05862124 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 6,926E-03 0,05848554 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 6,926E-03 0,05835047 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 6,926E-03 0,05821602 ! ethanol metabolic process GO:0006067 6 5 0,000 6,926E-03 0,05808219 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 6,926E-03 0,05794897 ! cobalt ion transport GO:0006824 5 5 0,000 6,926E-03 0,05781637 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 6,926E-03 0,05768437 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 6,926E-03 0,05755297 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 6,926E-03 0,05742217 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 6,926E-03 0,05729196 ! sterol carrier activity GO:0005498 6 5 0,000 6,926E-03 0,05716234 ! adaptation of signaling pathway GO:0022401 6 5 0,000 6,926E-03 0,0570333 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 6,926E-03 0,05690485 ! response to acid GO:0001101 7 5 0,000 6,926E-03 0,05677697 ! fibril organization GO:0043206 5 5 0,000 6,926E-03 0,05664967 ! malate metabolic process GO:0006108 6 5 0,000 6,926E-03 0,05652294 ! regulation of dopamine uptake GO:0051584 7 5 0,000 6,926E-03 0,05639677 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 6,926E-03 0,05627116 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 6,926E-03 0,05614612 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 6,926E-03 0,05602162 ! protein maturation by protein folding GO:0022417 5 5 0,000 6,926E-03 0,05589768 ! activation of protein kinase B activity GO:0032148 15 5 0,000 6,926E-03 0,05577429 ! origin recognition complex GO:0000808 5 5 0,000 6,926E-03 0,05565144 ! neurexin binding GO:0042043 6 5 0,000 6,926E-03 0,05552913 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 6,926E-03 0,05540735 ! protein amino acid dealkylation GO:0008214 5 5 0,000 6,926E-03 0,05528611 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 6,926E-03 0,0551654 ! lipoic acid binding GO:0031405 5 5 0,000 6,926E-03 0,05504521 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 6,926E-03 0,05492555 ! lithium ion binding GO:0031403 6 5 0,000 6,926E-03 0,0548064 ! grooming behavior GO:0007625 7 5 0,000 6,926E-03 0,05468778 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 6,926E-03 0,05456966 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 6,926E-03 0,05445205 ! lymph vessel development GO:0001945 6 5 0,000 6,926E-03 0,05433495 ! bicarbonate transport GO:0015701 5 5 0,000 6,926E-03 0,05421835 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 6,926E-03 0,05410225 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 6,926E-03 0,05398665 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 6,926E-03 0,05387154 ! endothelial cell proliferation GO:0001935 8 5 0,000 6,926E-03 0,05375692 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 6,926E-03 0,05364279 ! dorsal spinal cord development GO:0021516 6 5 0,000 6,926E-03 0,05352914 ! activation of MAPKKK activity GO:0000185 5 5 0,000 6,926E-03 0,05341597 ! synaptic vesicle maturation GO:0016188 6 5 0,000 6,926E-03 0,05330328 ! sphingoid catabolic process GO:0046521 5 5 0,000 6,926E-03 0,05319106 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 6,926E-03 0,05307931 ! neutrophil mediated immunity GO:0002446 5 5 0,000 6,926E-03 0,05296803 ! intercellular canaliculus GO:0046581 5 5 0,000 6,926E-03 0,05285722 ! dopamine binding GO:0035240 7 5 0,000 6,926E-03 0,05274687 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 6,926E-03 0,05263698 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 6,926E-03 0,05252755 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 6,926E-03 0,05241857 ! amine oxidase activity GO:0008131 7 5 0,000 6,926E-03 0,05231005 ! monocyte activation GO:0042117 9 5 0,000 6,926E-03 0,05220197 ! negative regulation of protein binding GO:0032091 5 5 0,000 6,926E-03 0,05209434 ! regulation of response to food GO:0032095 5 5 0,000 6,926E-03 0,05198715 ! response to food GO:0032094 6 5 0,000 6,926E-03 0,0518804 ! positive regulation of protein binding GO:0032092 5 5 0,000 6,926E-03 0,05177408 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 6,926E-03 0,05166821 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 6,926E-03 0,05156276 ! hedgehog receptor activity GO:0008158 5 5 0,000 6,926E-03 0,05145774 ! lipoprotein catabolic process GO:0042159 5 5 0,000 6,926E-03 0,05135316 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 6,926E-03 0,05124899 ! purine salvage GO:0043101 7 5 0,000 6,926E-03 0,05114525 ! small-subunit processome GO:0032040 5 5 0,000 6,926E-03 0,05104192 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 6,926E-03 0,05093902 ! ciliary rootlet GO:0035253 5 5 0,000 6,926E-03 0,05083652 ! myosin heavy chain binding GO:0032036 5 5 0,000 6,926E-03 0,05073444 ! nucleobase transport GO:0015851 5 5 0,000 6,926E-03 0,05063277 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 6,926E-03 0,05053151 ! GPI anchor binding GO:0034235 6 5 0,000 6,926E-03 0,05043064 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,926E-03 0,05033018 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 6,926E-03 0,05023012 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 6,926E-03 0,05013046 ! basic amino acid transport GO:0015802 5 5 0,000 6,926E-03 0,05003119 ! dendritic shaft GO:0043198 5 5 0,000 6,926E-03 0,04993232 ! terminal button GO:0043195 7 5 0,000 6,926E-03 0,04983383 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 6,926E-03 0,04973573 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 6,926E-03 0,04963802 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 6,926E-03 0,04954069 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 6,926E-03 0,04944374 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 6,926E-03 0,04934717 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 6,926E-03 0,04925098 ! response to UV-C GO:0010225 15 5 0,000 6,926E-03 0,04915516 ! positive regulation of organ growth GO:0046622 5 5 0,000 6,926E-03 0,04905971 ! response to arsenic GO:0046685 6 5 0,000 6,926E-03 0,04896464 ! IgE binding GO:0019863 5 5 0,000 6,926E-03 0,04886993 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 6,926E-03 0,04877558 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 6,926E-03 0,0486816 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 6,926E-03 0,04858799 ! response to copper ion GO:0046688 5 5 0,000 6,926E-03 0,04849473 ! response to cadmium ion GO:0046686 5 5 0,000 6,926E-03 0,04840182 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 6,926E-03 0,04830928 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 6,926E-03 0,04821709 ! protein autoprocessing GO:0016540 6 5 0,000 6,926E-03 0,04812524 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 6,926E-03 0,04803375 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 6,926E-03 0,0479426 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 6,926E-03 0,0478518 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 6,926E-03 0,04776135 ! mitotic recombination GO:0006312 15 5 0,000 6,926E-03 0,04767123 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 6,926E-03 0,04758146 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,926E-03 0,04749202 ! membrane to membrane docking GO:0022614 5 5 0,000 6,926E-03 0,04740291 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 6,926E-03 0,04731414 ! translation activator activity GO:0008494 5 5 0,000 6,926E-03 0,04722571 ! somatostatin receptor activity GO:0004994 5 5 0,000 6,926E-03 0,0471376 ! melanocortin receptor activity GO:0004977 6 5 0,000 6,926E-03 0,04704982 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 6,926E-03 0,04696237 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 6,926E-03 0,04687524 ! salivary gland morphogenesis GO:0007435 5 5 0,000 6,926E-03 0,04678843 ! galactosidase activity GO:0015925 5 5 0,000 6,926E-03 0,04670195 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 6,926E-03 0,04661578 ! cellular response to nutrient GO:0031670 5 5 0,000 6,926E-03 0,04652993 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 6,926E-03 0,0464444 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 6,926E-03 0,04635918 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 6,926E-03 0,04627427 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 6,926E-03 0,04618968 ! A band GO:0031672 5 5 0,000 6,926E-03 0,04610539 ! heat generation GO:0031649 5 5 0,000 6,926E-03 0,04602141 ! flagellum organization GO:0043064 5 5 0,000 6,926E-03 0,04593773 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 6,926E-03 0,04585436 ! disaccharide metabolic process GO:0005984 6 5 0,000 6,926E-03 0,04577129 ! glycogen catabolic process GO:0005980 16 5 0,000 6,926E-03 0,04568852 ! dopamine biosynthetic process GO:0042416 6 5 0,000 6,926E-03 0,04560605 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 6,926E-03 0,04552388 ! chromocenter GO:0010369 5 5 0,000 6,926E-03 0,045442 ! glial cell migration GO:0008347 5 5 0,000 6,926E-03 0,04536042 ! epidermal growth factor receptor binding GO:0005154 7 5 0,000 6,926E-03 0,04527913 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 6,926E-03 0,04519813 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 6,926E-03 0,04511742 ! growth hormone receptor binding GO:0005131 5 5 0,000 6,926E-03 0,04503699 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 6,926E-03 0,04495686 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 6,926E-03 0,044877 ! aminomethyltransferase activity GO:0004047 5 5 0,000 6,926E-03 0,04479743 ! aminoacylase activity GO:0004046 5 5 0,000 6,926E-03 0,04471815 ! penetration of zona pellucida GO:0007341 6 5 0,000 6,926E-03 0,04463914 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 6,926E-03 0,04456041 ! nucleus localization GO:0051647 5 5 0,000 6,926E-03 0,04448196 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 6,926E-03 0,04440378 ! carnitine metabolic process GO:0009437 5 5 0,000 6,926E-03 0,04432588 GO:0006577|betaine metabolic process, ! spindle GO:0005819 126 92 1,000 7,191E-03 0,04594294 ! cell cycle arrest GO:0007050 103 93 1,000 7,343E-03 0,04683077 ! regulation of cytoskeleton organization GO:0051493 133 93 1,000 7,343E-03 0,04674904 ! homophilic cell adhesion GO:0007156 107 95 1,000 7,651E-03 0,04862482 ! immune effector process GO:0002252 110 95 1,000 7,651E-03 0,04854025 ! intermediate filament GO:0005882 102 98 1,000 8,124E-03 0,05145016 GO:0045111|intermediate filament cytoskeleton, ! negative regulation of cellular component organization GO:0051129 132 99 1,000 8,284E-03 0,05237547 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,306E-03 0,05241985 ! regulation of helicase activity GO:0051095 6 6 0,000 8,306E-03 0,05232931 ! response to oxygen radical GO:0000305 6 6 0,000 8,306E-03 0,05223909 ! positive regulation of axon extension GO:0045773 7 6 0,000 8,306E-03 0,05214918 ! forebrain neuron differentiation GO:0021879 6 6 0,000 8,306E-03 0,05205957 ! forebrain regionalization GO:0021871 7 6 0,000 8,306E-03 0,05197028 ! meiotic prophase I GO:0007128 7 6 0,000 8,306E-03 0,05188129 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 8,306E-03 0,0517926 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 8,306E-03 0,05170422 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 8,306E-03 0,05161614 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 8,306E-03 0,05152835 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 8,306E-03 0,05144087 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 8,306E-03 0,05135368 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 8,306E-03 0,05126679 ! protein amino acid sulfation GO:0006477 9 6 0,000 8,306E-03 0,05118019 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 8,306E-03 0,05109388 ! establishment of tissue polarity GO:0007164 8 6 0,000 8,306E-03 0,05100787 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 8,306E-03 0,05092214 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 8,306E-03 0,0508367 ! embryonic camera-type eye development GO:0031076 9 6 0,000 8,306E-03 0,05075154 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 8,306E-03 0,05066668 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 8,306E-03 0,05058209 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 8,306E-03 0,05049779 ! Notch receptor processing GO:0007220 7 6 0,000 8,306E-03 0,05041376 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 8,306E-03 0,05033002 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 8,306E-03 0,05024655 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 8,306E-03 0,05016336 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 8,306E-03 0,05008045 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 8,306E-03 0,04999781 ! neurofilament GO:0005883 7 6 0,000 8,306E-03 0,04991544 ! glial cell fate commitment GO:0021781 7 6 0,000 8,306E-03 0,04983334 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 8,306E-03 0,04975151 ! dynactin complex GO:0005869 7 6 0,000 8,306E-03 0,04966995 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 8,306E-03 0,04958866 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 8,306E-03 0,04950763 ! oocyte maturation GO:0001556 6 6 0,000 8,306E-03 0,04942687 ! DNA replication origin binding GO:0003688 6 6 0,000 8,306E-03 0,04934637 ! reflex GO:0060004 10 6 0,000 8,306E-03 0,04926613 ! positive regulation of glycolysis GO:0045821 6 6 0,000 8,306E-03 0,04918616 ! parathyroid gland development GO:0060017 6 6 0,000 8,306E-03 0,04910644 ! anagen GO:0042640 7 6 0,000 8,306E-03 0,04902698 ! protein-cofactor linkage GO:0018065 15 6 0,000 8,306E-03 0,04894777 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 8,306E-03 0,04886883 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 8,306E-03 0,04879013 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 8,306E-03 0,04871169 ! skeletal myofibril assembly GO:0014866 6 6 0,000 8,306E-03 0,0486335 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 8,306E-03 0,04855556 ! cysteine metabolic process GO:0006534 7 6 0,000 8,306E-03 0,04847788 ! glycine catabolic process GO:0006546 6 6 0,000 8,306E-03 0,04840043 ! adenohypophysis development GO:0021984 6 6 0,000 8,306E-03 0,04832324 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 8,306E-03 0,04824629 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 8,306E-03 0,04816959 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 8,306E-03 0,04809313 ! microtubule nucleation GO:0007020 7 6 0,000 8,306E-03 0,04801691 ! proline biosynthetic process GO:0006561 8 6 0,000 8,306E-03 0,04794094 ! tryptophan metabolic process GO:0006568 6 6 0,000 8,306E-03 0,0478652 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 8,306E-03 0,0477897 ! thyroid hormone generation GO:0006590 6 6 0,000 8,306E-03 0,04771444 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 8,306E-03 0,04763942 ! retinoid X receptor binding GO:0046965 7 6 0,000 8,306E-03 0,04756463 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 8,306E-03 0,04749008 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 8,306E-03 0,04741576 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 8,306E-03 0,04734168 ! sister chromatid cohesion GO:0007062 6 6 0,000 8,306E-03 0,04726782 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 8,306E-03 0,04719419 ! positive regulation of transporter activity GO:0032411 8 6 0,000 8,306E-03 0,0471208 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 8,306E-03 0,04704763 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 8,306E-03 0,04697469 ! p53 binding GO:0002039 6 6 0,000 8,306E-03 0,04690197 ! demethylase activity GO:0032451 6 6 0,000 8,306E-03 0,04682948 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 8,306E-03 0,04675721 ! regulation of platelet activation GO:0010543 7 6 0,000 8,306E-03 0,04668517 ! lipid phosphatase activity GO:0042577 7 6 0,000 8,306E-03 0,04661334 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 8,306E-03 0,04654174 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 8,306E-03 0,04647036 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 8,306E-03 0,04639919 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 8,306E-03 0,04632824 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 8,306E-03 0,04625751 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 8,306E-03 0,046187 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 8,306E-03 0,0461167 ! LIM domain binding GO:0030274 7 6 0,000 8,306E-03 0,04604661 ! negative regulation of translational initiation GO:0045947 6 6 0,000 8,306E-03 0,04597674 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 8,306E-03 0,04590708 ! 5S class rRNA transcription GO:0042791 6 6 0,000 8,306E-03 0,04583763 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 8,306E-03 0,04576839 ! axon guidance receptor activity GO:0008046 6 6 0,000 8,306E-03 0,04569935 ! zinc ion homeostasis GO:0055069 7 6 0,000 8,306E-03 0,04563053 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 8,306E-03 0,04556191 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 8,306E-03 0,0454935 ! protein targeting to lysosome GO:0006622 6 6 0,000 8,306E-03 0,0454253 ! hyaluronan metabolic process GO:0030212 8 6 0,000 8,306E-03 0,04535729 ! protein retention in ER lumen GO:0006621 6 6 0,000 8,306E-03 0,0452895 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 8,306E-03 0,0452219 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 8,306E-03 0,0451545 ! dynein binding GO:0045502 6 6 0,000 8,306E-03 0,04508731 ! regulation of dendrite development GO:0050773 6 6 0,000 8,306E-03 0,04502032 ! peptidyl-arginine modification GO:0018195 6 6 0,000 8,306E-03 0,04495352 ! eating behavior GO:0042755 7 6 0,000 8,306E-03 0,04488692 ! protein localization to chromosome GO:0034502 8 6 0,000 8,306E-03 0,04482052 ! Hsp90 protein binding GO:0051879 7 6 0,000 8,306E-03 0,04475432 ! glycolipid binding GO:0051861 7 6 0,000 8,306E-03 0,04468831 ! MutLalpha complex binding GO:0032405 8 6 0,000 8,306E-03 0,04462249 ! mast cell activation GO:0045576 6 6 0,000 8,306E-03 0,04455687 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 8,306E-03 0,04449144 ! nucleoside catabolic process GO:0009164 7 6 0,000 8,306E-03 0,04442621 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 8,306E-03 0,04436116 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 8,306E-03 0,0442963 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 8,306E-03 0,04423164 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 8,306E-03 0,04416716 ! lipoxygenase activity GO:0016165 6 6 0,000 8,306E-03 0,04410287 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 8,306E-03 0,04403877 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 8,306E-03 0,04397485 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 8,306E-03 0,04391112 ! DNA replication factor C complex GO:0005663 7 6 0,000 8,306E-03 0,04384757 ! DNA replication factor A complex GO:0005662 7 6 0,000 8,306E-03 0,04378421 ! establishment of chromosome localization GO:0051303 15 6 0,000 8,306E-03 0,04372103 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 8,306E-03 0,04365803 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 8,306E-03 0,04359521 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 8,306E-03 0,04353258 ! chromatin assembly complex GO:0005678 16 6 0,000 8,306E-03 0,04347012 ! sex chromatin GO:0001739 6 6 0,000 8,306E-03 0,04340784 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 8,306E-03 0,04334574 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 8,306E-03 0,04328382 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 8,306E-03 0,04322207 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 8,306E-03 0,0431605 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 8,306E-03 0,04309911 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 8,306E-03 0,04303789 ! phosphatidylserine binding GO:0001786 6 6 0,000 8,306E-03 0,04297684 ! alpha-mannosidase activity GO:0004559 8 6 0,000 8,306E-03 0,04291597 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 8,306E-03 0,04285526 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 8,306E-03 0,04279473 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 8,306E-03 0,04273438 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 8,306E-03 0,04267419 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 8,306E-03 0,04261417 ! leading edge membrane GO:0031256 8 6 0,000 8,306E-03 0,04255431 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 8,306E-03 0,04249463 ! CARD domain binding GO:0050700 6 6 0,000 8,306E-03 0,04243512 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 8,306E-03 0,04237577 ! COPII vesicle coat GO:0030127 7 6 0,000 8,306E-03 0,04231658 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 8,306E-03 0,04225756 ! glutathione biosynthetic process GO:0006750 7 6 0,000 8,306E-03 0,04219871 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 8,306E-03 0,04214002 ! positive regulation of epidermis development GO:0045684 8 6 0,000 8,306E-03 0,04208149 ! proteasome regulator activity GO:0010860 6 6 0,000 8,306E-03 0,04202312 ! ceramidase activity GO:0017040 6 6 0,000 8,306E-03 0,04196492 ! antibiotic transport GO:0042891 7 6 0,000 8,306E-03 0,04190688 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 8,306E-03 0,04184899 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 8,306E-03 0,04179127 ! sodium channel regulator activity GO:0017080 6 6 0,000 8,306E-03 0,04173371 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,306E-03 0,0416763 ! regulation of protein homodimerization activity GO:0043496 9 6 0,000 8,306E-03 0,04161906 ! response to fluid shear stress GO:0034405 6 6 0,000 8,306E-03 0,04156196 ! lymph node development GO:0048535 6 6 0,000 8,306E-03 0,04150503 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 8,306E-03 0,04144825 ! triglyceride catabolic process GO:0019433 15 6 0,000 8,306E-03 0,04139163 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 8,306E-03 0,04133516 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 8,306E-03 0,04127884 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 8,306E-03 0,04122268 ! negative regulation of lipase activity GO:0060192 6 6 0,000 8,306E-03 0,04116667 ! activation of innate immune response GO:0002218 6 6 0,000 8,306E-03 0,04111082 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 8,306E-03 0,04105511 ! sarcoglycan complex GO:0016012 8 6 0,000 8,306E-03 0,04099956 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 8,306E-03 0,04094415 ! neural plate development GO:0001840 7 6 0,000 8,306E-03 0,0408889 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 8,306E-03 0,04083379 ! catecholamine transport GO:0051937 6 6 0,000 8,306E-03 0,04077883 ! ether hydrolase activity GO:0016803 7 6 0,000 8,306E-03 0,04072402 ! FACIT collagen GO:0005593 6 6 0,000 8,306E-03 0,04066936 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 8,306E-03 0,04061484 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 8,306E-03 0,04056047 ! collagen type IV GO:0005587 6 6 0,000 8,306E-03 0,04050625 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 8,306E-03 0,04045217 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 8,306E-03 0,04039823 ! drug metabolic process GO:0017144 6 6 0,000 8,306E-03 0,04034444 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 8,306E-03 0,04029079 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 8,306E-03 0,04023728 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 8,306E-03 0,04018392 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 8,306E-03 0,04013069 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 8,306E-03 0,04007761 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 8,306E-03 0,04002467 ! cellular anion homeostasis GO:0030002 6 6 0,000 8,306E-03 0,03997186 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 8,306E-03 0,0399192 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 8,306E-03 0,03986667 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 8,306E-03 0,03981429 ! behavioral response to cocaine GO:0048148 9 6 0,000 8,306E-03 0,03976204 ! translation initiation factor binding GO:0031369 6 6 0,000 8,306E-03 0,03970992 ! nucleotide-sugar transport GO:0015780 6 6 0,000 8,306E-03 0,03965795 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 8,306E-03 0,03960611 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 8,306E-03 0,0395544 ! quaternary ammonium group binding GO:0050997 7 6 0,000 8,306E-03 0,03950283 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 8,306E-03 0,0394514 ! reproductive behavior GO:0019098 8 6 0,000 8,306E-03 0,03940009 ! response to growth hormone stimulus GO:0060416 7 6 0,000 8,306E-03 0,03934892 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 8,306E-03 0,03929789 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 8,306E-03 0,03924698 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 8,306E-03 0,03919621 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 8,306E-03 0,03914557 ! induction of positive chemotaxis GO:0050930 7 6 0,000 8,306E-03 0,03909506 ! cohesin complex GO:0008278 6 6 0,000 8,306E-03 0,03904468 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 8,306E-03 0,03899443 ! citrate metabolic process GO:0006101 7 6 0,000 8,306E-03 0,03894431 ! myelin sheath GO:0043209 8 6 0,000 8,306E-03 0,03889432 ! phototransduction, visible light GO:0007603 6 6 0,000 8,306E-03 0,03884445 ! opsonization GO:0008228 7 6 0,000 8,306E-03 0,03879471 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 8,306E-03 0,03874511 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 8,306E-03 0,03869562 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 8,306E-03 0,03864627 ! regulation of potassium ion transport GO:0043266 8 6 0,000 8,306E-03 0,03859703 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 8,306E-03 0,03854793 ! chemoattractant activity GO:0042056 6 6 0,000 8,306E-03 0,03849895 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 8,306E-03 0,03845009 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 8,306E-03 0,03840136 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 8,306E-03 0,03835275 ! leukocyte degranulation GO:0043299 6 6 0,000 8,306E-03 0,03830426 ! bile acid and bile salt transport GO:0015721 7 6 0,000 8,306E-03 0,0382559 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 8,306E-03 0,03820766 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 8,306E-03 0,03815954 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 8,306E-03 0,03811154 ! DNA topoisomerase activity GO:0003916 6 6 0,000 8,306E-03 0,03806366 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 8,306E-03 0,0380159 ! ceramide biosynthetic process GO:0046513 6 6 0,000 8,306E-03 0,03796826 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 8,306E-03 0,03792074 ! activin receptor activity GO:0017002 7 6 0,000 8,306E-03 0,03787334 ! astrocyte differentiation GO:0048708 6 6 0,000 8,306E-03 0,03782606 ! syncytium formation GO:0006949 6 6 0,000 8,306E-03 0,03777889 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 8,306E-03 0,03773185 ! neutrophil activation GO:0042119 6 6 0,000 8,306E-03 0,03768492 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 8,306E-03 0,0376381 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 8,306E-03 0,0375914 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 8,306E-03 0,03754482 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 8,306E-03 0,03749836 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 8,306E-03 0,03745201 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 8,306E-03 0,03740577 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 8,306E-03 0,03735965 ! neuron apoptosis GO:0051402 7 6 0,000 8,306E-03 0,03731364 ! folic acid transport GO:0015884 8 6 0,000 8,306E-03 0,03726774 ! carnitine transport GO:0015879 6 6 0,000 8,306E-03 0,03722196 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 8,306E-03 0,03717628 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 8,306E-03 0,03713073 ! S-methyltransferase activity GO:0008172 6 6 0,000 8,306E-03 0,03708528 ! phospholipase D activity GO:0004630 6 6 0,000 8,306E-03 0,03703994 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 8,306E-03 0,03699472 ! intercalated disc GO:0014704 8 6 0,000 8,306E-03 0,0369496 ! G2/M transition checkpoint GO:0031576 24 6 0,000 8,306E-03 0,03690459 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 8,306E-03 0,0368597 ! IgG binding GO:0019864 6 6 0,000 8,306E-03 0,03681491 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 8,306E-03 0,03677023 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 8,306E-03 0,03672566 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 8,306E-03 0,0366812 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 8,306E-03 0,03663685 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 8,306E-03 0,0365926 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 8,306E-03 0,03654846 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 8,306E-03 0,03650442 ! dendrite morphogenesis GO:0048813 7 6 0,000 8,306E-03 0,0364605 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 8,306E-03 0,03641667 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 8,306E-03 0,03637296 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 8,306E-03 0,03632934 ! nucleosome disassembly GO:0006337 7 6 0,000 8,306E-03 0,03628583 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 8,306E-03 0,03624243 ! regulation of mast cell activation GO:0033003 6 6 0,000 8,306E-03 0,03619913 ! tetracycline transporter activity GO:0008493 7 6 0,000 8,306E-03 0,03615593 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 8,306E-03 0,03611284 ! receptor internalization GO:0031623 8 6 0,000 8,306E-03 0,03606985 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 8,306E-03 0,03602696 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 8,306E-03 0,03598417 ! histamine receptor activity GO:0004969 7 6 0,000 8,306E-03 0,03594149 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 8,306E-03 0,0358989 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 8,306E-03 0,03585642 ! protein deubiquitination GO:0016579 6 6 0,000 8,306E-03 0,03581403 ! axonal fasciculation GO:0007413 7 6 0,000 8,306E-03 0,03577175 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 8,306E-03 0,03572957 ! cytidine deaminase activity GO:0004126 6 6 0,000 8,306E-03 0,03568748 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 8,306E-03 0,0356455 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 8,306E-03 0,03560361 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 8,306E-03 0,03556182 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 8,306E-03 0,03552013 ! glycine binding GO:0016594 9 6 0,000 8,306E-03 0,03547854 ! apical protein localization GO:0045176 7 6 0,000 8,306E-03 0,03543704 ! ankyrin binding GO:0030506 6 6 0,000 8,306E-03 0,03539565 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 8,306E-03 0,03535434 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 8,306E-03 0,03531314 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 8,306E-03 0,03527203 ! progesterone metabolic process GO:0042448 6 6 0,000 8,306E-03 0,03523101 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 8,306E-03 0,0351901 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 8,306E-03 0,03514927 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 8,306E-03 0,03510854 ! ATP catabolic process GO:0006200 6 6 0,000 8,306E-03 0,03506791 ! CoA carboxylase activity GO:0016421 6 6 0,000 8,306E-03 0,03502737 ! determination of adult lifespan GO:0008340 6 6 0,000 8,306E-03 0,03498692 ! S-acyltransferase activity GO:0016417 6 6 0,000 8,306E-03 0,03494657 ! somatic stem cell maintenance GO:0035019 6 6 0,000 8,306E-03 0,0349063 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 8,306E-03 0,03486614 ! IkappaB kinase complex GO:0008385 7 6 0,000 8,306E-03 0,03482606 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 8,306E-03 0,03478608 ! store-operated calcium channel activity GO:0015279 6 6 0,000 8,306E-03 0,03474618 ! alkaline phosphatase activity GO:0004035 7 6 0,000 8,306E-03 0,03470638 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 8,306E-03 0,03466667 ! unconventional myosin complex GO:0016461 8 6 0,000 8,306E-03 0,03462705 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 8,446E-03 0,03517262 ! tRNA transcription GO:0009304 7 7 0,000 9,683E-03 0,04027921 ! respiratory burst GO:0045730 7 7 0,000 9,683E-03 0,04023334 ! telencephalon cell migration GO:0022029 8 7 0,000 9,683E-03 0,04018756 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 9,683E-03 0,0401419 ! cation:chloride symporter activity GO:0015377 8 7 0,000 9,683E-03 0,04009633 ! RNA cap binding GO:0000339 8 7 0,000 9,683E-03 0,04005087 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 9,683E-03 0,04000551 ! ephrin receptor binding GO:0046875 9 7 0,000 9,683E-03 0,03996026 ! male meiosis I GO:0007141 7 7 0,000 9,683E-03 0,03991511 ! synapsis GO:0007129 7 7 0,000 9,683E-03 0,03987005 GO:0070192|chromosome organization involved in meiosis, ! insulin receptor substrate binding GO:0043560 10 7 0,000 9,683E-03 0,03982511 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 9,683E-03 0,03978026 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 9,683E-03 0,03973551 ! signal peptide processing GO:0006465 7 7 0,000 9,683E-03 0,03969086 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 9,683E-03 0,03964632 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 9,683E-03 0,03960187 ! macrophage chemotaxis GO:0048246 7 7 0,000 9,683E-03 0,03955752 ! Golgi cisterna membrane GO:0032580 7 7 0,000 9,683E-03 0,03951328 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 9,683E-03 0,03946913 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 9,683E-03 0,03942508 ! smoothened signaling pathway GO:0007224 8 7 0,000 9,683E-03 0,03938112 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 9,683E-03 0,03933727 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 9,683E-03 0,03929351 ! cytoplasmic microtubule GO:0005881 7 7 0,000 9,683E-03 0,03924985 ! Arp2/3 protein complex GO:0005885 8 7 0,000 9,683E-03 0,03920629 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 9,683E-03 0,03916283 ! ATPase binding GO:0051117 8 7 0,000 9,683E-03 0,03911946 ! positive regulation of isotype switching GO:0045830 7 7 0,000 9,683E-03 0,03907618 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,683E-03 0,039033 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 9,683E-03 0,03898992 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 9,683E-03 0,03894693 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,683E-03 0,03890404 ! thymic T cell selection GO:0045061 16 7 0,000 9,683E-03 0,03886124 ! transepithelial chloride transport GO:0030321 7 7 0,000 9,683E-03 0,03881854 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 9,683E-03 0,03877593 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 9,683E-03 0,03873341 ! negative regulation of survival gene product expression GO:0008634 9 7 0,000 9,683E-03 0,03869098 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 9,683E-03 0,03864865 ! melanocyte differentiation GO:0030318 8 7 0,000 9,683E-03 0,03860641 ! malate dehydrogenase activity GO:0016615 8 7 0,000 9,683E-03 0,03856427 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 9,683E-03 0,03852221 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 9,683E-03 0,03848025 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 9,683E-03 0,03843838 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 9,683E-03 0,0383966 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 9,683E-03 0,03835491 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 9,683E-03 0,03831331 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 9,683E-03 0,0382718 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 9,683E-03 0,03823038 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 9,683E-03 0,03818905 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 9,683E-03 0,03814781 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 9,683E-03 0,03810665 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 9,683E-03 0,03806559 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 9,683E-03 0,03802462 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 9,683E-03 0,03798373 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 9,683E-03 0,03794293 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 9,683E-03 0,03790222 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 9,683E-03 0,0378616 ! melanosome organization GO:0032438 7 7 0,000 9,683E-03 0,03782106 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 9,683E-03 0,03778061 ! mesodermal cell differentiation GO:0048333 9 7 0,000 9,683E-03 0,03774024 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 9,683E-03 0,03769997 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,683E-03 0,03765977 ! chondrocyte differentiation GO:0002062 7 7 0,000 9,683E-03 0,03761967 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 9,683E-03 0,03757965 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 9,683E-03 0,03753971 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 9,683E-03 0,03749986 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 9,683E-03 0,03746009 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 9,683E-03 0,03742041 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 9,683E-03 0,03738081 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 9,683E-03 0,0373413 ! Schwann cell differentiation GO:0014037 8 7 0,000 9,683E-03 0,03730187 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 9,683E-03 0,03726252 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 9,683E-03 0,03722325 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 9,683E-03 0,03718407 ! vinculin binding GO:0017166 9 7 0,000 9,683E-03 0,03714497 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 9,683E-03 0,03710595 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 9,683E-03 0,03706702 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 9,683E-03 0,03702816 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 9,683E-03 0,03698939 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 9,683E-03 0,0369507 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 9,683E-03 0,03691209 ! cardiac muscle cell development GO:0055013 8 7 0,000 9,683E-03 0,03687356 ! fibrinolysis GO:0042730 9 7 0,000 9,683E-03 0,03683511 ! response to tropane GO:0014073 10 7 0,000 9,683E-03 0,03679674 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 9,683E-03 0,03675845 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 9,683E-03 0,03672024 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 9,683E-03 0,03668211 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 9,683E-03 0,03664405 ! laminin-1 complex GO:0005606 7 7 0,000 9,683E-03 0,03660608 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 9,683E-03 0,03656819 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 9,683E-03 0,03653037 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 9,683E-03 0,03649263 ! regulation of cell division GO:0051302 7 7 0,000 9,683E-03 0,03645497 ! holo TFIIH complex GO:0005675 7 7 0,000 9,683E-03 0,03641739 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 9,683E-03 0,03637989 ! chitinase activity GO:0004568 7 7 0,000 9,683E-03 0,03634246 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 9,683E-03 0,03630511 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 9,683E-03 0,03626783 ! regulation of respiratory burst GO:0060263 8 7 0,000 9,683E-03 0,03623063 ! prophase GO:0051324 8 7 0,000 9,683E-03 0,03619351 ! peptidyl-histidine modification GO:0018202 8 7 0,000 9,683E-03 0,03615647 ! BBSome GO:0034464 7 7 0,000 9,683E-03 0,0361195 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 9,683E-03 0,0360826 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,683E-03 0,03604578 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 9,683E-03 0,03600904 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 9,683E-03 0,03597237 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 9,683E-03 0,03593578 ! regulation of synaptogenesis GO:0051963 7 7 0,000 9,683E-03 0,03589926 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 9,683E-03 0,03586281 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 9,683E-03 0,03582644 ! glycolipid catabolic process GO:0019377 7 7 0,000 9,683E-03 0,03579014 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 9,683E-03 0,03575392 ! circadian behavior GO:0048512 9 7 0,000 9,683E-03 0,03571776 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 9,683E-03 0,03568169 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 9,683E-03 0,03564568 ! striatum development GO:0021756 7 7 0,000 9,683E-03 0,03560975 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 9,683E-03 0,03557389 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 9,683E-03 0,0355381 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 9,683E-03 0,03550238 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 9,683E-03 0,03546674 ! dystroglycan complex GO:0016011 9 7 0,000 9,683E-03 0,03543116 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 9,683E-03 0,03539566 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 9,683E-03 0,03536023 ! peroxiredoxin activity GO:0051920 7 7 0,000 9,683E-03 0,03532487 ! muscle adaptation GO:0043500 7 7 0,000 9,683E-03 0,03528958 ! regulation of muscle adaptation GO:0043502 7 7 0,000 9,683E-03 0,03525436 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 9,683E-03 0,03521921 ! lysogeny GO:0030069 7 7 0,000 9,683E-03 0,03518413 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 9,683E-03 0,03514912 ! sequestering of metal ion GO:0051238 9 7 0,000 9,683E-03 0,03511418 ! membrane attack complex GO:0005579 7 7 0,000 9,683E-03 0,03507931 ! fibrinogen complex GO:0005577 7 7 0,000 9,683E-03 0,03504451 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 9,683E-03 0,03500978 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 9,683E-03 0,03497512 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 9,683E-03 0,03494052 ! GABA receptor binding GO:0050811 8 7 0,000 9,683E-03 0,034906 ! sheet-forming collagen GO:0030935 7 7 0,000 9,683E-03 0,03487154 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 9,683E-03 0,03483715 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 9,683E-03 0,03480283 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 9,683E-03 0,03476857 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 9,683E-03 0,03473438 ! 7S RNA binding GO:0008312 8 7 0,000 9,683E-03 0,03470026 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 9,683E-03 0,03466621 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 9,683E-03 0,03463222 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 9,683E-03 0,0345983 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 9,683E-03 0,03456445 ! Golgi to endosome transport GO:0006895 8 7 0,000 9,683E-03 0,03453066 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 9,683E-03 0,03449694 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 9,683E-03 0,03446329 ! fibril GO:0043205 7 7 0,000 9,683E-03 0,0344297 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,683E-03 0,03439617 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,683E-03 0,03436271 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 9,683E-03 0,03432932 ! sensory perception of bitter taste GO:0050913 7 7 0,000 9,683E-03 0,03429599 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,683E-03 0,03426272 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 9,683E-03 0,03422952 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 9,683E-03 0,03419639 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 9,683E-03 0,03416332 ! equilibrioception GO:0050957 10 7 0,000 9,683E-03 0,03413031 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 9,683E-03 0,03409736 ! titin binding GO:0031432 7 7 0,000 9,683E-03 0,03406448 ! chemosensory behavior GO:0007635 9 7 0,000 9,683E-03 0,03403167 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 9,683E-03 0,03399891 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 9,683E-03 0,03396622 ! cobalamin binding GO:0031419 7 7 0,000 9,683E-03 0,03393359 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 9,683E-03 0,03390103 ! response to axon injury GO:0048678 9 7 0,000 9,683E-03 0,03386852 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 9,683E-03 0,03383608 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 9,683E-03 0,0338037 ! F-actin capping protein complex GO:0008290 8 7 0,000 9,683E-03 0,03377138 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 9,683E-03 0,03373913 ! cGMP-mediated signaling GO:0019934 8 7 0,000 9,683E-03 0,03370694 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 9,683E-03 0,0336748 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 9,683E-03 0,03364273 ! senescence GO:0010149 8 7 0,000 9,683E-03 0,03361072 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 9,683E-03 0,03357877 ! nuclear localization sequence binding GO:0008139 8 7 0,000 9,683E-03 0,03354688 ! galactose metabolic process GO:0006012 8 7 0,000 9,683E-03 0,03351506 ! vesicle fusion GO:0006906 8 7 0,000 9,683E-03 0,03348329 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 9,683E-03 0,03345158 ! intracellular pH reduction GO:0051452 7 7 0,000 9,683E-03 0,03341993 ! glycerol ether catabolic process GO:0044269 16 7 0,000 9,683E-03 0,03338834 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 9,683E-03 0,03335682 ! ruffle organization GO:0031529 9 7 0,000 9,683E-03 0,03332535 ! nucleoside transport GO:0015858 8 7 0,000 9,683E-03 0,03329394 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 9,683E-03 0,03326259 ! inclusion body GO:0016234 7 7 0,000 9,683E-03 0,0332313 ! Cajal body GO:0015030 7 7 0,000 9,683E-03 0,03320006 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 9,683E-03 0,03316889 ! rRNA modification GO:0000154 7 7 0,000 9,683E-03 0,03313778 ! PcG protein complex GO:0031519 7 7 0,000 9,683E-03 0,03310672 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 9,683E-03 0,03307572 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 9,683E-03 0,03304478 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 9,683E-03 0,0330139 ! apolipoprotein binding GO:0034185 9 7 0,000 9,683E-03 0,03298307 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 9,683E-03 0,0329523 ! segment specification GO:0007379 9 7 0,000 9,683E-03 0,03292159 ! pronucleus GO:0045120 25 7 0,000 9,683E-03 0,03289094 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 9,683E-03 0,03286034 ! Rac GTPase activator activity GO:0030675 9 7 0,000 9,683E-03 0,0328298 ! preribosome GO:0030684 7 7 0,000 9,683E-03 0,03279932 ! DNA topological change GO:0006265 7 7 0,000 9,683E-03 0,03276889 ! DNA ligation GO:0006266 8 7 0,000 9,683E-03 0,03273852 ! hair follicle maturation GO:0048820 8 7 0,000 9,683E-03 0,03270821 ! renal water homeostasis GO:0003091 7 7 0,000 9,683E-03 0,03267795 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 9,683E-03 0,03264775 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 9,683E-03 0,03261761 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 9,683E-03 0,03258752 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 9,683E-03 0,03255748 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 9,683E-03 0,0325275 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 9,683E-03 0,03249758 ! phosphofructokinase activity GO:0008443 7 7 0,000 9,683E-03 0,03246771 ! gap junction channel activity GO:0005243 8 7 0,000 9,683E-03 0,0324379 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 9,683E-03 0,03240814 ! histone methylation GO:0016571 7 7 0,000 9,683E-03 0,03237843 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 9,683E-03 0,03234878 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 9,683E-03 0,03231918 ! mitochondrion morphogenesis GO:0070584 9 7 0,000 9,683E-03 0,03228964 ! muscle cell proliferation GO:0033002 8 7 0,000 9,683E-03 0,03226015 ! transcription termination GO:0006353 9 7 0,000 9,683E-03 0,03223072 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 9,683E-03 0,03220134 ! cytidylyltransferase activity GO:0070567 8 7 0,000 9,683E-03 0,03217201 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 9,683E-03 0,03214274 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 9,683E-03 0,03211352 ! salivary gland development GO:0007431 7 7 0,000 9,683E-03 0,03208435 ! glucosidase activity GO:0015926 8 7 0,000 9,683E-03 0,03205523 ! NuRD complex GO:0016581 8 7 0,000 9,683E-03 0,03202617 ! negative regulation of nuclear division GO:0051784 7 7 0,000 9,683E-03 0,03199716 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 9,683E-03 0,03196821 ! response to redox state GO:0051775 8 7 0,000 9,683E-03 0,0319393 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 9,683E-03 0,03191045 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 9,683E-03 0,03188165 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 9,683E-03 0,0318529 ! actin monomer binding GO:0003785 7 7 0,000 9,683E-03 0,03182421 ! protein prenyltransferase activity GO:0008318 8 7 0,000 9,683E-03 0,03179556 ! endosome to lysosome transport GO:0008333 7 7 0,000 9,683E-03 0,03176697 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 9,683E-03 0,03173843 ! germ cell migration GO:0008354 7 7 0,000 9,683E-03 0,03170994 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 9,683E-03 0,0316815 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 9,683E-03 0,03165311 ! CoA-ligase activity GO:0016405 8 7 0,000 9,683E-03 0,03162477 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 9,683E-03 0,03159648 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 9,683E-03 0,03156825 ! embryonic heart tube development GO:0035050 8 7 0,000 9,683E-03 0,03154006 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 9,683E-03 0,03151193 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 9,683E-03 0,03148384 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 9,683E-03 0,0314558 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 9,683E-03 0,03142782 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,683E-03 0,03139988 ! adenylate kinase activity GO:0004017 8 7 0,000 9,683E-03 0,031372 ! negative regulation of immune effector process GO:0002698 13 7 0,000 9,683E-03 0,03134416 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 9,683E-03 0,03131637 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 9,683E-03 0,03128863 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 0,01105931 0,03570296 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 0,01105931 0,0356714 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 0,01105931 0,03563988 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 0,01105931 0,03560843 ! proteasome regulatory particle GO:0005838 8 8 0,000 0,01105931 0,03557703 ! SMAD protein complex assembly GO:0007183 10 8 0,000 0,01105931 0,03554568 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 0,01105931 0,03551439 ! protein self-association GO:0043621 8 8 0,000 0,01105931 0,03548316 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 0,01105931 0,03545198 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 0,01105931 0,03542085 ! neurotransmitter uptake GO:0001504 8 8 0,000 0,01105931 0,03538978 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 0,01105931 0,03535876 ! guanylate cyclase activity GO:0004383 9 8 0,000 0,01105931 0,0353278 ! troponin complex GO:0005861 8 8 0,000 0,01105931 0,03529689 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 0,01105931 0,03526604 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 0,01105931 0,03523524 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 0,01105931 0,03520449 ! middle ear morphogenesis GO:0042474 10 8 0,000 0,01105931 0,0351738 ! ganglioside metabolic process GO:0001573 8 8 0,000 0,01105931 0,03514316 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 0,01105931 0,03511258 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 0,01105931 0,03508204 ! ciliary or flagellar motility GO:0001539 8 8 0,000 0,01105931 0,03505156 ! pathogenesis GO:0009405 8 8 0,000 0,01105931 0,03502114 ! pH reduction GO:0045851 9 8 0,000 0,01105931 0,03499076 ! small protein activating enzyme activity GO:0008641 10 8 0,000 0,01105931 0,03496044 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 0,01105931 0,03493017 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 0,01105931 0,03489996 ! hemoglobin metabolic process GO:0020027 8 8 0,000 0,01105931 0,03486979 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 0,01105931 0,03483968 ! arginine catabolic process GO:0006527 9 8 0,000 0,01105931 0,03480962 ! T-tubule GO:0030315 9 8 0,000 0,01105931 0,03477961 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 0,01105931 0,03474966 ! histidine catabolic process GO:0006548 8 8 0,000 0,01105931 0,03471975 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 0,01105931 0,0346899 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 0,01105931 0,03466009 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 0,01105931 0,03463034 ! proline metabolic process GO:0006560 10 8 0,000 0,01105931 0,03460064 ! L-serine metabolic process GO:0006563 9 8 0,000 0,01105931 0,03457099 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 0,01105931 0,0345414 ! melanosome membrane GO:0033162 9 8 0,000 0,01105931 0,03451185 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01105931 0,03448235 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 0,01105931 0,0344529 ! pericentriolar material GO:0000242 9 8 0,000 0,01105931 0,03442351 ! reverse cholesterol transport GO:0043691 8 8 0,000 0,01105931 0,03439416 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 0,01105931 0,03436486 ! melanin metabolic process GO:0006582 10 8 0,000 0,01105931 0,03433562 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 0,01105931 0,03430642 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 0,01105931 0,03427727 ! Golgi lumen GO:0005796 8 8 0,000 0,01105931 0,03424817 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 0,01105931 0,03421913 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 0,01105931 0,03419013 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 0,01105931 0,03416118 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 0,01105931 0,03413228 ! stereocilium bundle GO:0032421 11 8 0,000 0,01105931 0,03410342 ! forebrain cell migration GO:0021885 9 8 0,000 0,01105931 0,03407462 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 0,01105931 0,03404586 ! osteoblast development GO:0002076 11 8 0,000 0,01105931 0,03401716 ! retinoic acid metabolic process GO:0042573 8 8 0,000 0,01105931 0,0339885 ! retinol metabolic process GO:0042572 8 8 0,000 0,01105931 0,03395989 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 0,01105931 0,03393133 ! structural constituent of epidermis GO:0030280 9 8 0,000 0,01105931 0,03390281 ! clathrin binding GO:0030276 10 8 0,000 0,01105931 0,03387435 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 0,01105931 0,03384593 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 0,01105931 0,03381756 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 0,01105931 0,03378924 ! motor axon guidance GO:0008045 8 8 0,000 0,01105931 0,03376096 ! protein targeting to vacuole GO:0006623 8 8 0,000 0,01105931 0,03373273 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 0,01105931 0,03370455 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 0,01105931 0,03367642 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 0,01105931 0,03364833 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 0,01105931 0,03362029 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01105931 0,0335923 ! protein-lipid complex assembly GO:0065005 8 8 0,000 0,01105931 0,03356435 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 0,01105931 0,03353645 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 0,01105931 0,0335086 ! regulation of dopamine secretion GO:0014059 9 8 0,000 0,01105931 0,03348079 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 0,01105931 0,03345303 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 0,01105931 0,03342531 ! subpallium development GO:0021544 8 8 0,000 0,01105931 0,03339764 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 0,01105931 0,03337002 ! icosanoid secretion GO:0032309 10 8 0,000 0,01105931 0,03334244 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 0,01105931 0,0333149 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 0,01105931 0,03328742 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 0,01105931 0,03325997 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 0,01105931 0,03323258 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 0,01105931 0,03320523 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 0,01105931 0,03317792 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 0,01105931 0,03315066 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 0,01105931 0,03312344 ! ubiquinone metabolic process GO:0006743 9 8 0,000 0,01105931 0,03309627 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 0,01105931 0,03306914 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 0,01105931 0,03304206 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 0,01105931 0,03301502 ! Wnt receptor activity GO:0042813 11 8 0,000 0,01105931 0,03298802 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 0,01105931 0,03296107 ! detection of calcium ion GO:0005513 9 8 0,000 0,01105931 0,03293416 ! negative regulation of glucose import GO:0046325 9 8 0,000 0,01105931 0,0329073 ! blastocyst growth GO:0001832 8 8 0,000 0,01105931 0,03288048 ! regulation of fibrinolysis GO:0051917 8 8 0,000 0,01105931 0,0328537 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 0,01105931 0,03282697 ! cerebellar cortex formation GO:0021697 9 8 0,000 0,01105931 0,03280028 ! complement binding GO:0001848 11 8 0,000 0,01105931 0,03277364 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 0,01105931 0,03274704 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 0,01105931 0,03272048 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 0,01105931 0,03269396 ! amino sugar catabolic process GO:0046348 8 8 0,000 0,01105931 0,03266749 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 0,01105931 0,03264106 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 0,01105931 0,03261467 ! positive regulation of amine transport GO:0051954 9 8 0,000 0,01105931 0,03258833 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 0,01105931 0,03256203 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 0,01105931 0,03253577 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01105931 0,03250955 ! Golgi transport complex GO:0017119 8 8 0,000 0,01105931 0,03248337 ! GDP binding GO:0019003 9 8 0,000 0,01105931 0,03245724 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 0,01105931 0,03243115 ! prostate gland development GO:0030850 17 8 0,000 0,01105931 0,0324051 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 0,01105931 0,03237909 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 0,01105931 0,03235313 ! phosphate transport GO:0006817 9 8 0,000 0,01105931 0,0323272 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 0,01105931 0,03230132 ! oligopeptide transport GO:0006857 8 8 0,000 0,01105931 0,03227548 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 0,01105931 0,03224968 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 0,01105931 0,03222392 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 0,01105931 0,0321982 ! lipoprotein transport GO:0042953 9 8 0,000 0,01105931 0,03217253 ! estrogen metabolic process GO:0008210 8 8 0,000 0,01105931 0,03214689 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 0,01105931 0,0321213 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 0,01105931 0,03209574 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 0,01105931 0,03207023 ! T-helper 1 type immune response GO:0042088 8 8 0,000 0,01105931 0,03204476 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 0,01105931 0,03201933 ! response to amphetamine GO:0001975 11 8 0,000 0,01105931 0,03199393 ! mechanosensory behavior GO:0007638 8 8 0,000 0,01105931 0,03196858 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 0,01105931 0,03194327 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 0,01105931 0,031918 ! C-X-C chemokine binding GO:0019958 8 8 0,000 0,01105931 0,03189277 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 0,01105931 0,03186757 ! glycerolipid catabolic process GO:0046503 17 8 0,000 0,01105931 0,03184242 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 0,01105931 0,03181731 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 0,01105931 0,03179224 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 0,01105931 0,0317672 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 0,01105931 0,03174221 ! pigment granule organization GO:0048753 9 8 0,000 0,01105931 0,03171726 ! GTP-dependent protein binding GO:0030742 11 8 0,000 0,01105931 0,03169234 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 0,01105931 0,03166746 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 0,01105931 0,03164263 ! regulation of pigmentation during development GO:0048070 11 8 0,000 0,01105931 0,03161783 ! macrophage activation GO:0042116 8 8 0,000 0,01105931 0,03159307 ! poly(A) RNA binding GO:0008143 8 8 0,000 0,01105931 0,03156835 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 0,01105931 0,03154367 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 0,01105931 0,03151902 ! asymmetric protein localization GO:0008105 9 8 0,000 0,01105931 0,03149442 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 0,01105931 0,03146985 ! neurotrophin binding GO:0043121 10 8 0,000 0,01105931 0,03144532 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 0,01105931 0,03142083 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 0,01105931 0,03139638 ! phagocytosis, engulfment GO:0006911 10 8 0,000 0,01105931 0,03137197 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 0,01105931 0,03134759 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 0,01105931 0,03132325 ! UV protection GO:0009650 9 8 0,000 0,01105931 0,03129895 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 0,01105931 0,03127469 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 0,01105931 0,03125046 ! glutathione peroxidase activity GO:0004602 17 8 0,000 0,01105931 0,03122628 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 0,01105931 0,03120213 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 0,01105931 0,03117801 ! ferric iron binding GO:0008199 9 8 0,000 0,01105931 0,03115394 ! response to UV-B GO:0010224 10 8 0,000 0,01105931 0,0311299 ! intermediate filament organization GO:0045109 8 8 0,000 0,01105931 0,0311059 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 0,01105931 0,03108193 ! cellular extravasation GO:0045123 9 8 0,000 0,01105931 0,03105801 ! skeletal muscle contraction GO:0003009 8 8 0,000 0,01105931 0,03103412 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 0,01105931 0,03101026 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01105931 0,03098644 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 0,01105931 0,03096266 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 0,01105931 0,03093892 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 0,01105931 0,03091521 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 0,01105931 0,03089154 ! erythrocyte development GO:0048821 9 8 0,000 0,01105931 0,0308679 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 0,01105931 0,0308443 ! ribosome assembly GO:0042255 8 8 0,000 0,01105931 0,03082074 ! NADPH oxidase complex GO:0043020 8 8 0,000 0,01105931 0,03079721 ! mRNA cleavage GO:0006379 9 8 0,000 0,01105931 0,03077372 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 0,01105931 0,03075027 ! opioid receptor activity GO:0004985 8 8 0,000 0,01105931 0,03072685 ! zymogen activation GO:0031638 9 8 0,000 0,01105931 0,03070346 ! coenzyme A metabolic process GO:0015936 8 8 0,000 0,01105931 0,03068011 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 0,01105931 0,0306568 ! costamere GO:0043034 8 8 0,000 0,01105931 0,03063352 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 0,01105931 0,03061028 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 0,01105931 0,03058707 ! sarcomere organization GO:0045214 9 8 0,000 0,01105931 0,0305639 ! wide pore channel activity GO:0022829 9 8 0,000 0,01105931 0,03054076 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 0,01105931 0,03051766 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 0,01105931 0,0304946 ! hormone catabolic process GO:0042447 9 8 0,000 0,01105931 0,03047156 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 0,01105931 0,03044857 ! cGMP biosynthetic process GO:0006182 9 8 0,000 0,01105931 0,0304256 ! lysozyme activity GO:0003796 10 8 0,000 0,01105931 0,03040267 ! death receptor binding GO:0005123 8 8 0,000 0,01105931 0,03037978 ! protein modification by small protein removal GO:0070646 9 8 0,000 0,01105931 0,03035692 ! adult feeding behavior GO:0008343 9 8 0,000 0,01105931 0,0303341 ! microtubule basal body GO:0005932 8 8 0,000 0,01105931 0,03031131 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 0,01105931 0,03028855 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 0,01105931 0,03026583 ! calcium-release channel activity GO:0015278 8 8 0,000 0,01105931 0,03024314 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 0,01105931 0,03022049 ! behavioral response to nicotine GO:0035095 9 8 0,000 0,01105931 0,03019787 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 0,01105931 0,03017528 ! adenosine deaminase activity GO:0004000 8 8 0,000 0,01105931 0,03015273 ! NAD biosynthetic process GO:0009435 9 8 0,000 0,01105931 0,03013021 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01243342 0,0338486 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01243342 0,03382336 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01243342 0,03379816 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01243342 0,03377299 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01243342 0,03374786 ! myotube differentiation GO:0014902 9 9 0,000 0,01243342 0,03372277 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01243342 0,03369772 ! N-glycan processing GO:0006491 10 9 0,000 0,01243342 0,0336727 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01243342 0,03364772 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01243342 0,03362278 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01243342 0,03359787 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01243342 0,033573 ! RNA methylation GO:0001510 9 9 0,000 0,01243342 0,03354817 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01243342 0,03352337 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01243342 0,03349861 ! artery development GO:0060840 9 9 0,000 0,01243342 0,03347389 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01243342 0,03344921 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01243342 0,03342456 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01243342 0,03339994 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01243342 0,03337537 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01243342 0,03335083 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01243342 0,03332632 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01243342 0,03330185 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01243342 0,03327742 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01243342 0,03325302 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01243342 0,03322866 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01243342 0,03320434 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01243342 0,03318005 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01243342 0,03315579 ! urea metabolic process GO:0019627 19 9 0,000 0,01243342 0,03313157 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01243342 0,03310739 ! autophagic vacuole GO:0005776 11 9 0,000 0,01243342 0,03308324 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01243342 0,03305913 ! response to dietary excess GO:0002021 9 9 0,000 0,01243342 0,03303505 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01243342 0,03301101 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01243342 0,032987 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01243342 0,03296303 ! male sex determination GO:0030238 9 9 0,000 0,01243342 0,03293909 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01243342 0,03291518 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01243342 0,03289132 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01243342 0,03286748 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01243342 0,03284368 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01243342 0,03281992 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01243342 0,03279619 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01243342 0,03277249 ! spectrin GO:0008091 9 9 0,000 0,01243342 0,03274883 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01243342 0,0327252 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01243342 0,0327016 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01243342 0,03267804 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01243342 0,03265452 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01243342 0,03263102 ! neural tube patterning GO:0021532 10 9 0,000 0,01243342 0,03260757 ! fucose catabolic process GO:0019317 10 9 0,000 0,01243342 0,03258414 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01243342 0,03256075 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01243342 0,03253739 ! sterol catabolic process GO:0016127 10 9 0,000 0,01243342 0,03251407 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01243342 0,03249078 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01243342 0,03246752 ! SNARE complex GO:0031201 11 9 0,000 0,01243342 0,0324443 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01243342 0,0324211 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01243342 0,03239795 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01243342 0,03237482 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01243342 0,03235173 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01243342 0,03232867 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01243342 0,03230564 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01243342 0,03228265 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01243342 0,03225969 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01243342 0,03223676 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01243342 0,03221387 ! detection of bacterium GO:0016045 10 9 0,000 0,01243342 0,032191 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01243342 0,03216817 ! embryonic gut development GO:0048566 10 9 0,000 0,01243342 0,03214538 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01243342 0,03212261 ! desmosome GO:0030057 10 9 0,000 0,01243342 0,03209988 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01243342 0,03207717 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01243342 0,03205451 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01243342 0,03203187 ! actin filament polymerization GO:0030041 10 9 0,000 0,01243342 0,03200926 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01243342 0,03198669 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01243342 0,03196415 ! septin complex GO:0031105 10 9 0,000 0,01243342 0,03194164 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01243342 0,03191916 ! anchoring collagen GO:0030934 9 9 0,000 0,01243342 0,03189671 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01243342 0,0318743 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01243342 0,03185191 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01243342 0,03182956 ! GMP binding GO:0019002 11 9 0,000 0,01243342 0,03180724 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01243342 0,03178495 ! virus-host interaction GO:0019048 13 9 0,000 0,01243342 0,03176269 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01243342 0,03174047 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01243342 0,03171827 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01243342 0,0316961 ! non-recombinational repair GO:0000726 10 9 0,000 0,01243342 0,03167397 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01243342 0,03165187 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01243342 0,03162979 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01243342 0,03160775 ! social behavior GO:0035176 10 9 0,000 0,01243342 0,03158574 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01243342 0,03156376 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01243342 0,03154181 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01243342 0,03151989 ! mating GO:0007618 11 9 0,000 0,01243342 0,031498 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01243342 0,03147614 ! rhythmic behavior GO:0007622 11 9 0,000 0,01243342 0,03145432 ! phospholipid efflux GO:0033700 10 9 0,000 0,01243342 0,03143252 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01243342 0,03141075 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01243342 0,03138901 ! T cell proliferation GO:0042098 10 9 0,000 0,01243342 0,03136731 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01243342 0,03134563 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01243342 0,03132398 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01243342 0,03130236 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01243342 0,03128078 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01243342 0,03125922 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01243342 0,03123769 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01243342 0,03121619 ! ovulation GO:0030728 9 9 0,000 0,01243342 0,03119472 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01243342 0,03117328 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01243342 0,03115187 ! ER overload response GO:0006983 11 9 0,000 0,01243342 0,03113049 ! B cell proliferation GO:0042100 10 9 0,000 0,01243342 0,03110914 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01243342 0,03108782 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01243342 0,03106652 ! mannose metabolic process GO:0006013 13 9 0,000 0,01243342 0,03104526 ! lipid digestion GO:0044241 11 9 0,000 0,01243342 0,03102403 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01243342 0,03100282 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01243342 0,03098164 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01243342 0,03096049 ! brain morphogenesis GO:0048854 9 9 0,000 0,01243342 0,03093938 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01243342 0,03091829 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01243342 0,03089722 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01243342 0,03087619 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01243342 0,03085519 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01243342 0,03083421 ! kinesin binding GO:0019894 9 9 0,000 0,01243342 0,03081326 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01243342 0,03079235 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01243342 0,03077146 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01243342 0,03075059 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01243342 0,03072976 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01243342 0,03070895 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01243342 0,03068818 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01243342 0,03066743 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01243342 0,03064671 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01243342 0,03062601 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01243342 0,03060535 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01243342 0,03058471 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01243342 0,0305641 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01243342 0,03054352 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01243342 0,03052296 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01243342 0,03050244 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01243342 0,03048194 ! Notch binding GO:0005112 10 9 0,000 0,01243342 0,03046147 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01243342 0,03044102 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01243342 0,03042061 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01243342 0,03040022 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01243342 0,03037986 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,0138057 0,03371031 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,0138057 0,03368776 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,0138057 0,03366524 ! sleep GO:0030431 11 10 0,000 0,0138057 0,03364275 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,0138057 0,0336203 ! lipid particle GO:0005811 10 10 0,000 0,0138057 0,03359787 ! filopodium assembly GO:0046847 14 10 0,000 0,0138057 0,03357547 ! UTP metabolic process GO:0046051 12 10 0,000 0,0138057 0,0335531 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,0138057 0,03353076 ! guanylate kinase activity GO:0004385 14 10 0,000 0,0138057 0,03350845 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,0138057 0,03348617 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,0138057 0,03346392 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,0138057 0,0334417 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,0138057 0,03341951 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,0138057 0,03339735 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,0138057 0,03337522 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,0138057 0,03335311 ! lung alveolus development GO:0048286 11 10 0,000 0,0138057 0,03333104 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,0138057 0,033309 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0138057 0,03328698 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,0138057 0,03326499 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,0138057 0,03324304 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,0138057 0,03322111 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,0138057 0,03319921 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,0138057 0,03317734 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,0138057 0,0331555 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,0138057 0,03313369 ! histidine metabolic process GO:0006547 10 10 0,000 0,0138057 0,0331119 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,0138057 0,03309015 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,0138057 0,03306842 ! death receptor activity GO:0005035 11 10 0,000 0,0138057 0,03304672 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,0138057 0,03302505 ! entry into host cell GO:0030260 11 10 0,000 0,0138057 0,03300341 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,0138057 0,0329818 ! filamentous actin GO:0031941 11 10 0,000 0,0138057 0,03296021 ! behavioral fear response GO:0001662 12 10 0,000 0,0138057 0,03293865 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,0138057 0,03291713 ! negative regulation of ossification GO:0030279 12 10 0,000 0,0138057 0,03289563 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,0138057 0,03287415 ! macrophage differentiation GO:0030225 11 10 0,000 0,0138057 0,03285271 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,0138057 0,03283129 ! recycling endosome membrane GO:0055038 11 10 0,000 0,0138057 0,0328099 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,0138057 0,03278854 ! snRNA metabolic process GO:0016073 10 10 0,000 0,0138057 0,03276721 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,0138057 0,03274591 ! regulation of mitochondrial membrane potential GO:0051881 11 10 0,000 0,0138057 0,03272463 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,0138057 0,03270338 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,0138057 0,03268216 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,0138057 0,03266096 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,0138057 0,03263979 ! induction of an organ GO:0001759 12 10 0,000 0,0138057 0,03261865 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,0138057 0,03259754 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,0138057 0,03257646 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,0138057 0,0325554 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,0138057 0,03253437 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,0138057 0,03251336 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,0138057 0,03249239 ! ribonuclease P activity GO:0004526 10 10 0,000 0,0138057 0,03247144 ! COPI vesicle coat GO:0030126 12 10 0,000 0,0138057 0,03245052 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,0138057 0,03242962 ! vitamin transporter activity GO:0051183 12 10 0,000 0,0138057 0,03240875 ! snRNA binding GO:0017069 11 10 0,000 0,0138057 0,03238791 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,0138057 0,0323671 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,0138057 0,03234631 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,0138057 0,03232555 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,0138057 0,03230481 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,0138057 0,0322841 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,0138057 0,03226342 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,0138057 0,03224277 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,0138057 0,03222214 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,0138057 0,03220154 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,0138057 0,03218096 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,0138057 0,03216041 ! positive regulation of neuron apoptosis GO:0043525 11 10 0,000 0,0138057 0,03213989 ! extracellular matrix binding GO:0050840 11 10 0,000 0,0138057 0,03211939 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,0138057 0,03209892 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,0138057 0,03207847 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,0138057 0,03205805 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,0138057 0,03203766 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,0138057 0,03201729 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,0138057 0,03199695 ! thyroid gland development GO:0030878 12 10 0,000 0,0138057 0,03197664 ! DNA bending activity GO:0008301 11 10 0,000 0,0138057 0,03195635 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,0138057 0,03193608 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,0138057 0,03191584 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,0138057 0,03189563 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,0138057 0,03187544 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,0138057 0,03185528 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,0138057 0,03183515 ! regulation of glycolysis GO:0006110 11 10 0,000 0,0138057 0,03181504 ! nucleotidase activity GO:0008252 10 10 0,000 0,0138057 0,03179495 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,0138057 0,03177489 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,0138057 0,03175486 ! androgen metabolic process GO:0008209 11 10 0,000 0,0138057 0,03173485 ! lateral plasma membrane GO:0016328 13 10 0,000 0,0138057 0,03171486 ! MAP kinase kinase activity GO:0004708 12 10 0,000 0,0138057 0,0316949 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,0138057 0,03167497 ! startle response GO:0001964 13 10 0,000 0,0138057 0,03165506 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,0138057 0,03163518 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,0138057 0,03161532 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,0138057 0,03159548 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,0138057 0,03157568 ! spinal cord patterning GO:0021511 12 10 0,000 0,0138057 0,03155589 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,0138057 0,03153613 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,0138057 0,0315164 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,0138057 0,03149669 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,0138057 0,031477 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,0138057 0,03145734 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,0138057 0,0314377 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,0138057 0,03141809 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,0138057 0,03139851 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,0138057 0,03137894 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,0138057 0,0313594 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,0138057 0,03133989 ! adult heart development GO:0007512 14 10 0,000 0,0138057 0,0313204 ! neuromuscular junction development GO:0007528 12 10 0,000 0,0138057 0,03130093 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,0138057 0,03128149 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,0138057 0,03126207 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,0138057 0,03124268 ! signalosome GO:0008180 10 10 0,000 0,0138057 0,03122331 ! lysophospholipase activity GO:0004622 19 10 0,000 0,0138057 0,03120397 ! prefoldin complex GO:0016272 10 10 0,000 0,0138057 0,03118465 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,0138057 0,03116535 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,0138057 0,03114607 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,0138057 0,03112682 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,0138057 0,0311076 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,0138057 0,0310884 ! gland morphogenesis GO:0022612 11 10 0,000 0,0138057 0,03106922 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,0138057 0,03105006 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,0138057 0,03103093 ! peptide transporter activity GO:0015197 10 10 0,000 0,0138057 0,03101182 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,0138057 0,03099274 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,0138057 0,03097368 ! muscle maintenance GO:0046716 10 10 0,000 0,0138057 0,03095464 ! acid secretion GO:0046717 12 10 0,000 0,0138057 0,03093563 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,0138057 0,03091664 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,0138057 0,03089767 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,0138057 0,03087873 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,0138057 0,03085981 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,0138057 0,03084091 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,0138057 0,03082203 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,0138057 0,03080318 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,0138057 0,03078435 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,0138057 0,03076555 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,0138057 0,03074677 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,0138057 0,03072801 ! water channel activity GO:0015250 15 10 0,000 0,0138057 0,03070927 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,0138057 0,03069056 ! regulation of embryonic development GO:0045995 12 10 0,000 0,0138057 0,03067186 ! acrosome reaction GO:0007340 12 10 0,000 0,0138057 0,0306532 ! mitochondrion localization GO:0051646 10 10 0,000 0,0138057 0,03063455 ! cilium part GO:0044441 10 10 0,000 0,0138057 0,03061593 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01517615 0,03363462 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01517615 0,0336142 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01517615 0,0335938 ! centriole GO:0005814 11 11 0,000 0,01517615 0,03357343 ! cadmium ion binding GO:0046870 15 11 0,000 0,01517615 0,03355309 ! hemoglobin complex GO:0005833 13 11 0,000 0,01517615 0,03353276 ! CTP metabolic process GO:0046036 13 11 0,000 0,01517615 0,03351246 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01517615 0,03349219 ! response to pain GO:0048265 12 11 0,000 0,01517615 0,03347194 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01517615 0,03345172 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01517615 0,03343152 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01517615 0,03341134 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01517615 0,03339119 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01517615 0,03337106 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01517615 0,03335096 ! peptide antigen binding GO:0042605 14 11 0,000 0,01517615 0,03333088 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01517615 0,03331082 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01517615 0,03329079 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01517615 0,03327079 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01517615 0,03325081 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01517615 0,03323085 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01517615 0,03321091 ! protein homotetramerization GO:0051289 13 11 0,000 0,01517615 0,033191 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01517615 0,03317111 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01517615 0,03315125 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01517615 0,03313141 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01517615 0,0331116 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01517615 0,03309181 ! response to dsRNA GO:0043331 21 11 0,000 0,01517615 0,03307204 ! response to amine stimulus GO:0014075 15 11 0,000 0,01517615 0,03305229 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01517615 0,03303257 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01517615 0,03301287 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01517615 0,0329932 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01517615 0,03297355 ! retinal binding GO:0016918 11 11 0,000 0,01517615 0,03295392 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01517615 0,03293432 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01517615 0,03291474 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01517615 0,03289518 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01517615 0,03287565 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01517615 0,03285614 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01517615 0,03283665 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01517615 0,03281718 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01517615 0,03279774 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01517615 0,03277832 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01517615 0,03275893 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01517615 0,03273956 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01517615 0,03272021 ! midbrain development GO:0030901 12 11 0,000 0,01517615 0,03270088 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01517615 0,03268158 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01517615 0,0326623 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01517615 0,03264304 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01517615 0,0326238 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01517615 0,03260459 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01517615 0,0325854 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01517615 0,03256623 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01517615 0,03254708 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01517615 0,03252796 ! folic acid binding GO:0005542 12 11 0,000 0,01517615 0,03250886 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01517615 0,03248978 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01517615 0,03247073 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01517615 0,03245169 ! microspike assembly GO:0030035 15 11 0,000 0,01517615 0,03243268 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01517615 0,03241369 ! fibrillar collagen GO:0005583 12 11 0,000 0,01517615 0,03239473 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01517615 0,03237578 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01517615 0,03235686 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01517615 0,03233796 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01517615 0,03231908 ! synaptonemal complex GO:0000795 11 11 0,000 0,01517615 0,03230023 ! reproductive cellular process GO:0048610 13 11 0,000 0,01517615 0,03228139 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01517615 0,03226258 ! response to cAMP GO:0051591 11 11 0,000 0,01517615 0,03224379 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01517615 0,03222502 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01517615 0,03220628 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01517615 0,03218755 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01517615 0,03216885 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01517615 0,03215017 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01517615 0,03213151 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 0,000 0,01517615 0,03211287 ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01517615 0,03209426 ! drug transport GO:0015893 12 11 0,000 0,01517615 0,03207566 ! FMN binding GO:0010181 12 11 0,000 0,01517615 0,03205709 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01517615 0,03203854 ! water transporter activity GO:0005372 17 11 0,000 0,01517615 0,03202001 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01517615 0,0320015 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01517615 0,03198301 ! multicellular organism growth GO:0035264 12 11 0,000 0,01517615 0,03196454 ! integrator complex GO:0032039 11 11 0,000 0,01517615 0,0319461 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01517615 0,03192768 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01517615 0,03190927 ! brush border membrane GO:0031526 12 11 0,000 0,01517615 0,03189089 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01517615 0,03187253 ! macroautophagy GO:0016236 12 11 0,000 0,01517615 0,03185419 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01517615 0,03183588 ! neuromuscular junction GO:0031594 12 11 0,000 0,01517615 0,03181758 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01517615 0,03179931 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01517615 0,03178105 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01517615 0,03176282 ! response to antibiotic GO:0046677 13 11 0,000 0,01517615 0,0317446 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01517615 0,03172641 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01517615 0,03170824 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01517615 0,03169009 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01517615 0,03167196 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01517615 0,03165385 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01517615 0,03163577 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01517615 0,0316177 ! protein kinase C binding GO:0005080 11 11 0,000 0,01517615 0,03159965 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01517615 0,03158163 ! male genitalia development GO:0030539 15 11 0,000 0,01517615 0,03156362 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01517615 0,03154564 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01517615 0,03152767 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01517615 0,03150973 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01517615 0,0314918 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01517615 0,0314739 ! sterol transporter activity GO:0015248 11 11 0,000 0,01517615 0,03145602 ! response to nicotine GO:0035094 13 11 0,000 0,01517615 0,03143815 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01517615 0,03142031 ! rRNA transcription GO:0009303 12 12 0,000 0,01654476 0,03423443 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,01654476 0,03421502 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,01654476 0,03419564 ! superoxide anion generation GO:0042554 12 12 0,000 0,01654476 0,03417627 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,01654476 0,03415693 ! regulation of S phase GO:0033261 16 12 0,000 0,01654476 0,03413761 ! regulation of chemokine production GO:0032642 13 12 0,000 0,01654476 0,03411831 ! male meiosis GO:0007140 12 12 0,000 0,01654476 0,03409904 ! signal complex assembly GO:0007172 15 12 0,000 0,01654476 0,03407978 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,01654476 0,03406055 ! GTP metabolic process GO:0046039 14 12 0,000 0,01654476 0,03404134 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,01654476 0,03402215 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,01654476 0,03400299 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,01654476 0,03398384 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,01654476 0,03396471 ! cartilage condensation GO:0001502 14 12 0,000 0,01654476 0,03394561 ! polysome GO:0005844 14 12 0,000 0,01654476 0,03392653 ! hippocampus development GO:0021766 13 12 0,000 0,01654476 0,03390747 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,01654476 0,03388843 ! beta-amyloid binding GO:0001540 12 12 0,000 0,01654476 0,03386942 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,01654476 0,03385042 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,01654476 0,03383145 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,01654476 0,03381249 ! chylomicron GO:0042627 13 12 0,000 0,01654476 0,03379356 ! T cell selection GO:0045058 22 12 0,000 0,01654476 0,03377465 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,01654476 0,03375576 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,01654476 0,03373689 ! WW domain binding GO:0050699 12 12 0,000 0,01654476 0,03371804 ! methionine metabolic process GO:0006555 14 12 0,000 0,01654476 0,03369922 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,01654476 0,03368041 ! glycine metabolic process GO:0006544 14 12 0,000 0,01654476 0,03366163 ! plasma membrane organization GO:0007009 12 12 0,000 0,01654476 0,03364286 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01654476 0,03362412 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,01654476 0,0336054 ! Golgi organization GO:0007030 15 12 0,000 0,01654476 0,0335867 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01654476 0,03356802 ! mitotic spindle organization GO:0007052 13 12 0,000 0,01654476 0,03354936 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,01654476 0,03353072 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,01654476 0,0335121 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,01654476 0,03349351 ! temperature homeostasis GO:0001659 13 12 0,000 0,01654476 0,03347493 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,01654476 0,03345637 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01654476 0,03343784 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01654476 0,03341932 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,01654476 0,03340083 ! axon cargo transport GO:0008088 13 12 0,000 0,01654476 0,03338236 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,01654476 0,0333639 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,01654476 0,03334547 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,01654476 0,03332706 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,01654476 0,03330866 ! basal lamina GO:0005605 12 12 0,000 0,01654476 0,03329029 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,01654476 0,03327194 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,01654476 0,03325361 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,01654476 0,0332353 ! biomineral formation GO:0031214 14 12 0,000 0,01654476 0,03321701 ! water homeostasis GO:0030104 12 12 0,000 0,01654476 0,03319873 ! promoter binding GO:0010843 14 12 0,000 0,01654476 0,03318048 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,01654476 0,03316225 ! intestinal absorption GO:0050892 14 12 0,000 0,01654476 0,03314404 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,01654476 0,03312585 ! oocyte differentiation GO:0009994 13 12 0,000 0,01654476 0,03310768 ! oxygen transport GO:0015671 13 12 0,000 0,01654476 0,03308953 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,01654476 0,0330714 ! cholesterol efflux GO:0033344 13 12 0,000 0,01654476 0,03305329 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,01654476 0,03303519 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,01654476 0,03301712 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,01654476 0,03299907 ! tropomyosin binding GO:0005523 12 12 0,000 0,01654476 0,03298104 ! blastocyst formation GO:0001825 13 12 0,000 0,01654476 0,03296302 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,01654476 0,03294503 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,01654476 0,03292706 ! mannose binding GO:0005537 13 12 0,000 0,01654476 0,0329091 ! phosphoprotein binding GO:0051219 14 12 0,000 0,01654476 0,03289117 ! defense response to fungus GO:0050832 12 12 0,000 0,01654476 0,03287326 ! embryonic placenta development GO:0001892 16 12 0,000 0,01654476 0,03285536 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01654476 0,03283749 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,01654476 0,03281963 ! acyl-CoA binding GO:0000062 12 12 0,000 0,01654476 0,03280179 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,01654476 0,03278398 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,01654476 0,03276618 ! copper ion transport GO:0006825 12 12 0,000 0,01654476 0,0327484 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,01654476 0,03273064 ! inositol metabolic process GO:0006020 21 12 0,000 0,01654476 0,0327129 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,01654476 0,03269518 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,01654476 0,03267748 ! protein complex disassembly GO:0043241 15 12 0,000 0,01654476 0,03265979 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,01654476 0,03264213 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,01654476 0,03262449 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,01654476 0,03260686 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,01654476 0,03258925 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,01654476 0,03257167 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,01654476 0,0325541 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,01654476 0,03253655 ! endoderm development GO:0007492 13 12 0,000 0,01654476 0,03251902 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,01654476 0,03250151 ! focal adhesion formation GO:0048041 16 12 0,000 0,01654476 0,03248401 ! T cell receptor complex GO:0042101 31 12 0,000 0,01654476 0,03246654 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,01654476 0,03244909 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,01654476 0,03243165 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,01654476 0,03241423 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,01654476 0,03239683 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,01654476 0,03237945 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,01654476 0,03236209 ! retinol binding GO:0019841 12 12 0,000 0,01654476 0,03234475 ! regulation of organ growth GO:0046620 12 12 0,000 0,01654476 0,03232742 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,01654476 0,03231012 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,01654476 0,03229283 ! histone acetylation GO:0016573 13 12 0,000 0,01654476 0,03227556 ! ribosome binding GO:0043022 13 12 0,000 0,01654476 0,03225831 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,01654476 0,03224108 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,01654476 0,03222386 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,01654476 0,03220667 ! tissue regeneration GO:0042246 12 12 0,000 0,01654476 0,03218949 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,01654476 0,03217233 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,01654476 0,03215519 ! germ cell nucleus GO:0043073 14 12 0,000 0,01654476 0,03213807 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,01654476 0,03212097 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,01654476 0,03210388 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01654476 0,03208681 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01654476 0,03206977 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,01654476 0,03205273 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,01654476 0,03203572 ! dopamine metabolic process GO:0042417 15 12 0,000 0,01654476 0,03201873 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,01654476 0,03200175 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,01654476 0,03198479 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,01654476 0,03196785 ! bacterial binding GO:0008367 14 12 0,000 0,01654476 0,03195093 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01654476 0,03193402 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,01654476 0,03191713 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,01654476 0,03190026 ! localization within membrane GO:0051668 13 12 0,000 0,01654476 0,03188341 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,01654476 0,03186658 ! axoneme part GO:0044447 12 12 0,000 0,01654476 0,03184976 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01791155 0,03446273 ! neuron maturation GO:0042551 14 13 0,000 0,01791155 0,03444456 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01791155 0,03442641 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01791155 0,03440829 ! bone remodeling GO:0046849 14 13 0,000 0,01791155 0,03439018 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01791155 0,03437209 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01791155 0,03435401 ! striated muscle thin filament GO:0005865 14 13 0,000 0,01791155 0,03433596 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01791155 0,03431793 ! organelle fusion GO:0048284 16 13 0,000 0,01791155 0,03429991 ! palate development GO:0060021 15 13 0,000 0,01791155 0,03428192 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01791155 0,03426394 ! arginine metabolic process GO:0006525 14 13 0,000 0,01791155 0,03424598 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01791155 0,03422804 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01791155 0,03421012 ! response to retinoic acid GO:0032526 17 13 0,000 0,01791155 0,03419222 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01791155 0,03417434 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01791155 0,03415647 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01791155 0,03413863 ! fear response GO:0042596 15 13 0,000 0,01791155 0,0341208 ! epithelial cell development GO:0002064 22 13 0,000 0,01791155 0,03410299 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01791155 0,0340852 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01791155 0,03406743 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01791155 0,03404968 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01791155 0,03403195 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01791155 0,03401423 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01791155 0,03399653 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01791155 0,03397885 ! cranial nerve development GO:0021545 15 13 0,000 0,01791155 0,03396119 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01791155 0,03394355 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01791155 0,03392593 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01791155 0,03390832 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01791155 0,03389073 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01791155 0,03387316 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01791155 0,03385561 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01791155 0,03383808 ! NADP metabolic process GO:0006739 15 13 0,000 0,01791155 0,03382057 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01791155 0,03380307 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01791155 0,03378559 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01791155 0,03376813 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01791155 0,03375069 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01791155 0,03373327 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01791155 0,03371586 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01791155 0,03369847 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01791155 0,0336811 ! ADP binding GO:0043531 15 13 0,000 0,01791155 0,03366375 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01791155 0,03364641 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01791155 0,0336291 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01791155 0,0336118 ! neuron fate specification GO:0048665 25 13 0,000 0,01791155 0,03359452 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01791155 0,03357725 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01791155 0,03356001 ! water transport GO:0006833 18 13 0,000 0,01791155 0,03354278 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01791155 0,03352557 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01791155 0,03350838 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01791155 0,0334912 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01791155 0,03347404 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01791155 0,0334569 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01791155 0,03343978 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01791155 0,03342268 ! myoblast differentiation GO:0045445 15 13 0,000 0,01791155 0,03340559 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01791155 0,03338852 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01791155 0,03337147 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01791155 0,03335443 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01791155 0,03333742 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01791155 0,03332042 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01791155 0,03330343 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01791155 0,03328647 ! exocrine system development GO:0035272 14 13 0,000 0,01791155 0,03326952 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01791155 0,03325259 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01791155 0,03323567 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01791155 0,03321878 ! L-glutamate transport GO:0015813 14 13 0,000 0,01791155 0,0332019 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01791155 0,03318504 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01791155 0,03316819 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01791155 0,03315136 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01791155 0,03313455 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01791155 0,03311776 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01791155 0,03310098 ! genitalia development GO:0048806 18 13 0,000 0,01791155 0,03308422 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01791155 0,03306748 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01791155 0,03305075 ! histone deacetylation GO:0016575 14 13 0,000 0,01791155 0,03303404 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01791155 0,03301735 ! DNA methylation GO:0006306 15 13 0,000 0,01791155 0,03300067 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01791155 0,03298402 ! chromatin silencing GO:0006342 13 13 0,000 0,01791155 0,03296737 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01791155 0,03295075 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01791155 0,03293414 ! T cell homeostasis GO:0043029 14 13 0,000 0,01791155 0,03291755 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01791155 0,03290097 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01791155 0,03288442 ! response to gamma radiation GO:0010332 14 13 0,000 0,01791155 0,03286787 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01791155 0,03285135 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01791155 0,03283484 ! purine base metabolic process GO:0006144 15 13 0,000 0,01791155 0,03281835 ! cAMP binding GO:0030552 15 13 0,000 0,01791155 0,03280187 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01791155 0,03278542 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01791155 0,03276897 ! regulation of axon extension GO:0030516 16 13 0,000 0,01791155 0,03275255 ! drug transporter activity GO:0015238 14 13 0,000 0,01791155 0,03273614 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01791155 0,03271975 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01791155 0,03270337 ! response to cold GO:0009409 13 13 0,000 0,01791155 0,03268701 ! cadherin binding GO:0045296 16 13 0,000 0,01791155 0,03267067 ! nucleolar part GO:0044452 13 13 0,000 0,01791155 0,03265434 ! tRNA modification GO:0006400 14 14 0,000 0,01927651 0,03512523 ! cis-Golgi network GO:0005801 16 14 0,000 0,01927651 0,03510769 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,01927651 0,03509017 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,01927651 0,03507267 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,01927651 0,03505519 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,01927651 0,03503772 ! peroxisomal transport GO:0043574 14 14 0,000 0,01927651 0,03502027 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,01927651 0,03500284 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,01927651 0,03498543 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,01927651 0,03496803 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,01927651 0,03495065 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,01927651 0,03493329 ! caspase activator activity GO:0008656 16 14 0,000 0,01927651 0,03491594 ! MHC class II protein complex GO:0042613 19 14 0,000 0,01927651 0,03489861 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01927651 0,0348813 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,01927651 0,03486401 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,01927651 0,03484673 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,01927651 0,03482947 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01927651 0,03481223 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,01927651 0,03479501 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,01927651 0,0347778 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,01927651 0,03476061 ! response to vitamin A GO:0033189 18 14 0,000 0,01927651 0,03474343 ! actin filament bundle formation GO:0051017 16 14 0,000 0,01927651 0,03472628 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,01927651 0,03470913 ! plasma membrane fusion GO:0045026 15 14 0,000 0,01927651 0,03469201 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,01927651 0,0346749 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,01927651 0,03465782 ! protein export from nucleus GO:0006611 14 14 0,000 0,01927651 0,03464074 ! presynaptic membrane GO:0042734 14 14 0,000 0,01927651 0,03462369 ! negative regulation of immune response GO:0050777 21 14 0,000 0,01927651 0,03460665 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,01927651 0,03458962 ! neural crest cell migration GO:0001755 15 14 0,000 0,01927651 0,03457262 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,01927651 0,03455563 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,01927651 0,03453866 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,01927651 0,0345217 ! cofactor transport GO:0051181 16 14 0,000 0,01927651 0,03450476 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01927651 0,03448784 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,01927651 0,03447093 ! cobalt ion binding GO:0050897 14 14 0,000 0,01927651 0,03445405 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,01927651 0,03443717 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,01927651 0,03442032 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,01927651 0,03440348 ! gas transport GO:0015669 15 14 0,000 0,01927651 0,03438665 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,01927651 0,03436985 ! heme biosynthetic process GO:0006783 14 14 0,000 0,01927651 0,03435306 ! cerebellar cortex development GO:0021695 16 14 0,000 0,01927651 0,03433628 ! insulin secretion GO:0030073 17 14 0,000 0,01927651 0,03431953 ! tRNA binding GO:0000049 16 14 0,000 0,01927651 0,03430278 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,01927651 0,03428606 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,01927651 0,03426935 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,01927651 0,03425266 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,01927651 0,03423598 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,01927651 0,03421932 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,01927651 0,03420268 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,01927651 0,03418605 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,01927651 0,03416944 ! C-C chemokine binding GO:0019957 15 14 0,000 0,01927651 0,03415284 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,01927651 0,03413627 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,01927651 0,0341197 ! response to osmotic stress GO:0006970 17 14 0,000 0,01927651 0,03410316 ! fructose metabolic process GO:0006000 15 14 0,000 0,01927651 0,03408662 ! telomeric DNA binding GO:0042162 17 14 0,000 0,01927651 0,03407011 ! monoamine transport GO:0015844 15 14 0,000 0,01927651 0,03405361 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,01927651 0,03403713 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01927651 0,03402066 ! dendritic spine GO:0043197 15 14 0,000 0,01927651 0,03400421 ! stem cell development GO:0048864 14 14 0,000 0,01927651 0,03398778 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,01927651 0,03397136 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,01927651 0,03395495 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,01927651 0,03393857 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,01927651 0,03392219 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01927651 0,03390584 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,01927651 0,0338895 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01927651 0,03387317 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,01927651 0,03385686 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,01927651 0,03384057 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,01927651 0,03382429 ! mannosidase activity GO:0015923 19 14 0,000 0,01927651 0,03380803 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,01927651 0,03379179 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,01927651 0,03377556 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,01927651 0,03375934 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,01927651 0,03374314 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,01927651 0,03372696 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01927651 0,03371079 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,01927651 0,03369464 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,01927651 0,0336785 ! sperm-egg recognition GO:0035036 17 14 0,000 0,01927651 0,03366238 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,01927651 0,03364627 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,01927651 0,03363018 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,01927651 0,0336141 ! positive regulation of translation GO:0045727 17 15 0,000 0,02063965 0,03597393 ! nuclear replication fork GO:0043596 26 15 0,000 0,02063965 0,03595675 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,02063965 0,03593958 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,02063965 0,03592244 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,02063965 0,03590531 ! endothelial cell migration GO:0043542 16 15 0,000 0,02063965 0,03588819 ! lipid phosphorylation GO:0046834 19 15 0,000 0,02063965 0,03587109 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,02063965 0,03585401 ! response to vitamin GO:0033273 19 15 0,000 0,02063965 0,03583695 ! gene silencing by RNA GO:0031047 17 15 0,000 0,02063965 0,0358199 ! striated muscle thick filament GO:0005863 16 15 0,000 0,02063965 0,03580287 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,02063965 0,03578585 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,02063965 0,03576885 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,02063965 0,03575186 ! glutamate metabolic process GO:0006536 17 15 0,000 0,02063965 0,0357349 ! pituitary gland development GO:0021983 16 15 0,000 0,02063965 0,03571794 ! cholesterol binding GO:0015485 15 15 0,000 0,02063965 0,03570101 ! NAD metabolic process GO:0019674 17 15 0,000 0,02063965 0,03568409 ! protease binding GO:0002020 20 15 0,000 0,02063965 0,03566718 ! regulation of heart rate GO:0002027 20 15 0,000 0,02063965 0,0356503 ! actin filament bundle GO:0032432 18 15 0,000 0,02063965 0,03563342 GO:0001725|stress fiber, ! Golgi cisterna GO:0031985 17 15 0,000 0,02063965 0,03561657 ! regulation of exocytosis GO:0017157 16 15 0,000 0,02063965 0,03559973 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,02063965 0,0355829 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,02063965 0,0355661 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,02063965 0,0355493 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,02063965 0,03553253 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,02063965 0,03551577 ! neuron recognition GO:0008038 18 15 0,000 0,02063965 0,03549902 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,02063965 0,03548229 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,02063965 0,03546558 ! filopodium GO:0030175 17 15 0,000 0,02063965 0,03544888 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,02063965 0,0354322 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,02063965 0,03541553 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,02063965 0,03539888 ! peptide hormone binding GO:0017046 16 15 0,000 0,02063965 0,03538225 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,02063965 0,03536563 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,02063965 0,03534903 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,02063965 0,03533244 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,02063965 0,03531587 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,02063965 0,03529931 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,02063965 0,03528277 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,02063965 0,03526624 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,02063965 0,03524973 ! developmental induction GO:0031128 17 15 0,000 0,02063965 0,03523324 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,02063965 0,03521676 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,02063965 0,03520029 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,02063965 0,03518384 ! lactation GO:0007595 17 15 0,000 0,02063965 0,03516741 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,02063965 0,03515099 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02063965 0,03513459 ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,02063965 0,0351182 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,02063965 0,03510183 ! sulfate transport GO:0008272 16 15 0,000 0,02063965 0,03508547 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,02063965 0,03506913 ! bile acid metabolic process GO:0008206 17 15 0,000 0,02063965 0,0350528 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,02063965 0,03503649 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,02063965 0,0350202 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,02063965 0,03500392 ! heart looping GO:0001947 18 15 0,000 0,02063965 0,03498765 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,02063965 0,0349714 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,02063965 0,03495516 ! pigmentation during development GO:0048066 17 15 0,000 0,02063965 0,03493894 ! cytokine metabolic process GO:0042107 15 15 0,000 0,02063965 0,03492274 ! vesicle coating GO:0006901 17 15 0,000 0,02063965 0,03490655 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,02063965 0,03489037 ! neutral amino acid transport GO:0015804 18 15 0,000 0,02063965 0,03487421 ! L-amino acid transport GO:0015807 16 15 0,000 0,02063965 0,03485807 ! microfilament motor activity GO:0000146 15 15 0,000 0,02063965 0,03484194 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,02063965 0,03482582 ! regulation of vasodilation GO:0042312 25 15 0,000 0,02063965 0,03480972 ! DNA replication initiation GO:0006270 15 15 0,000 0,02063965 0,03479363 ! taste receptor activity GO:0008527 15 15 0,000 0,02063965 0,03477756 ! cellular pigmentation GO:0033059 16 15 0,000 0,02063965 0,03476151 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,02063965 0,03474547 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,02063965 0,03472944 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,02063965 0,03471343 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,02063965 0,03469743 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,02063965 0,03468145 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,02063965 0,03466548 ! ion gated channel activity GO:0022839 17 15 0,000 0,02063965 0,03464953 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,02063965 0,03463359 ! receptor activator activity GO:0030546 17 15 0,000 0,02063965 0,03461767 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,02063965 0,03460176 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,02063965 0,03458586 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,02063965 0,03456998 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,02063965 0,03455412 ! peptide hormone processing GO:0016486 19 15 0,000 0,02063965 0,03453827 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,02063965 0,03452243 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,02200096 0,03678254 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,02200096 0,03676569 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,02200096 0,03674885 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,02200096 0,03673204 ! kinesin complex GO:0005871 16 16 0,000 0,02200096 0,03671523 ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,02200096 0,03669844 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,02200096 0,03668167 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,02200096 0,03666491 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,02200096 0,03664817 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,02200096 0,03663145 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,02200096 0,03661473 ! lysosomal transport GO:0007041 16 16 0,000 0,02200096 0,03659804 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,02200096 0,03658136 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,02200096 0,03656469 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,02200096 0,03654804 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,02200096 0,03653141 ! myofibril assembly GO:0030239 17 16 0,000 0,02200096 0,03651478 GO:0055002|striated muscle cell development, ! G1 phase GO:0051318 17 16 0,000 0,02200096 0,03649818 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,02200096 0,03648159 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,02200096 0,03646501 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,02200096 0,03644845 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,02200096 0,03643191 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,02200096 0,03641538 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,02200096 0,03639886 ! steroid catabolic process GO:0006706 18 16 0,000 0,02200096 0,03638236 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,02200096 0,03636588 ! cell-cell recognition GO:0009988 19 16 0,000 0,02200096 0,03634941 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,02200096 0,03633295 ! spleen development GO:0048536 19 16 0,000 0,02200096 0,03631651 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,02200096 0,03630009 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,02200096 0,03628368 ! neural tube closure GO:0001843 19 16 0,000 0,02200096 0,03626728 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,02200096 0,0362509 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,02200096 0,03623454 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,02200096 0,03621818 ! viral genome replication GO:0019079 16 16 0,000 0,02200096 0,03620185 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,02200096 0,03618553 ! memory GO:0007613 18 16 0,000 0,02200096 0,03616922 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,02200096 0,03615293 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02200096 0,03613665 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,02200096 0,03612039 ! glycoprotein binding GO:0001948 19 16 0,000 0,02200096 0,03610414 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,02200096 0,0360879 ! syntaxin binding GO:0019905 18 16 0,000 0,02200096 0,03607168 ! myosin binding GO:0017022 17 16 0,000 0,02200096 0,03605548 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,02200096 0,03603929 ! fucose metabolic process GO:0006004 18 16 0,000 0,02200096 0,03602311 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,02200096 0,03600695 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,02200096 0,03599081 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,02200096 0,03597467 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,02200096 0,03595856 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,02200096 0,03594245 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,02200096 0,03592636 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,02200096 0,03591029 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 0,000 0,02200096 0,03589423 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,02200096 0,03587818 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,02200096 0,03586215 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,02200096 0,03584614 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,02200096 0,03583013 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,02200096 0,03581414 ! axoneme GO:0005930 16 16 0,000 0,02200096 0,03579817 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,02200096 0,03578221 ! anion exchanger activity GO:0015380 17 17 0,000 0,02336045 0,03797635 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,02336045 0,03795943 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,02336045 0,03794253 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,02336045 0,03792565 ! glial cell development GO:0021782 17 17 0,000 0,02336045 0,03790878 ! limbic system development GO:0021761 18 17 0,000 0,02336045 0,03789192 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,02336045 0,03787508 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,02336045 0,03785825 ! ephrin receptor activity GO:0005003 21 17 0,000 0,02336045 0,03784144 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,02336045 0,03782465 ! glutamine metabolic process GO:0006541 26 17 0,000 0,02336045 0,03780787 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,02336045 0,0377911 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,02336045 0,03777435 ! signal sequence binding GO:0005048 18 17 0,000 0,02336045 0,03775761 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,02336045 0,03774089 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,02336045 0,03772418 ! organelle subcompartment GO:0031984 19 17 0,000 0,02336045 0,03770749 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,02336045 0,03769081 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,02336045 0,03767415 ! membrane depolarization GO:0051899 19 17 0,000 0,02336045 0,0376575 ! oogenesis GO:0048477 20 17 0,000 0,02336045 0,03764087 ! nuclear outer membrane GO:0005640 21 17 0,000 0,02336045 0,03762425 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,02336045 0,03760765 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,02336045 0,03759106 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,02336045 0,03757448 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,02336045 0,03755792 ! organic cation transport GO:0015695 17 17 0,000 0,02336045 0,03754138 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,02336045 0,03752485 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,02336045 0,03750833 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,02336045 0,03749183 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,02336045 0,03747534 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,02336045 0,03745887 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,02336045 0,03744241 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,02336045 0,03742597 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,02336045 0,03740954 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02336045 0,03739312 ! lipid localization GO:0010876 19 17 0,000 0,02336045 0,03737672 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,02336045 0,03736034 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,02336045 0,03734397 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,02336045 0,03732761 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,02336045 0,03731127 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,02336045 0,03729494 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,02336045 0,03727862 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,02336045 0,03726232 ! response to hexose stimulus GO:0009746 20 17 0,000 0,02336045 0,03724604 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,02336045 0,03722976 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,02336045 0,03721351 ! AMP binding GO:0016208 19 17 0,000 0,02336045 0,03719726 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,02336045 0,03718103 ! receptor metabolic process GO:0043112 20 17 0,000 0,02336045 0,03716482 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,02336045 0,03714862 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,02336045 0,03713243 ! alcohol binding GO:0043178 20 17 0,000 0,02336045 0,03711626 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,02336045 0,0371001 ! visual learning GO:0008542 31 17 0,000 0,02336045 0,03708396 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,02336045 0,03706783 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,02336045 0,03705171 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,02336045 0,03703561 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,02336045 0,03701952 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,02336045 0,03700344 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,02336045 0,03698738 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,02336045 0,03697134 ! translation elongation factor activity GO:0003746 19 17 0,000 0,02336045 0,0369553 ! histone binding GO:0042393 26 17 0,000 0,02336045 0,03693929 ! cilium assembly GO:0042384 18 17 0,000 0,02336045 0,03692328 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,02336045 0,03690729 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,02336045 0,03689131 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,02336045 0,03687535 ! protein secretion GO:0009306 19 18 0,000 0,02471813 0,03900162 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02471813 0,03898475 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02471813 0,03896791 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02471813 0,03895107 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02471813 0,03893426 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02471813 0,03891745 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02471813 0,03890066 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02471813 0,03888389 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02471813 0,03886713 ! cornified envelope GO:0001533 22 18 0,000 0,02471813 0,03885038 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02471813 0,03883365 GO:0016101|diterpenoid metabolic process, ! actomyosin GO:0042641 21 18 0,000 0,02471813 0,03881693 ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02471813 0,03880023 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02471813 0,03878354 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02471813 0,03876687 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02471813 0,03875021 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02471813 0,03873356 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02471813 0,03871693 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02471813 0,03870032 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02471813 0,03868371 ! primary neural tube formation GO:0014020 21 18 0,000 0,02471813 0,03866713 ! recycling endosome GO:0055037 22 18 0,000 0,02471813 0,03865055 ! muscle cell development GO:0055001 20 18 0,000 0,02471813 0,03863399 ! kinase activator activity GO:0019209 22 18 0,000 0,02471813 0,03861745 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02471813 0,03860091 ! cerebellum development GO:0021549 20 18 0,000 0,02471813 0,0385844 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02471813 0,03856789 ! somitogenesis GO:0001756 20 18 0,000 0,02471813 0,0385514 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02471813 0,03853493 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02471813 0,03851847 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02471813 0,03850202 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02471813 0,03848559 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02471813 0,03846917 ! basal plasma membrane GO:0009925 21 18 0,000 0,02471813 0,03845277 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02471813 0,03843637 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02471813 0,03842 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02471813 0,03840364 ! negative regulation of translation GO:0017148 31 18 0,000 0,02471813 0,03838729 ! regulation of cell killing GO:0031341 24 18 0,000 0,02471813 0,03837095 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02471813 0,03835463 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02471813 0,03833832 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02471813 0,03832203 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02471813 0,03830575 ! protein complex scaffold GO:0032947 22 18 0,000 0,02471813 0,03828948 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02471813 0,03827323 ! dendrite development GO:0016358 22 18 0,000 0,02471813 0,03825699 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02471813 0,03824077 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02471813 0,03822456 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02471813 0,03820836 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02471813 0,03819218 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02471813 0,03817601 ! coreceptor activity GO:0015026 28 18 0,000 0,02471813 0,03815985 ! response to fungus GO:0009620 18 18 0,000 0,02471813 0,03814371 ! stem cell differentiation GO:0048863 18 18 0,000 0,02471813 0,03812758 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02471813 0,03811147 ! heart process GO:0003015 19 18 0,000 0,02471813 0,03809537 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02471813 0,03807928 ! vasodilation GO:0042311 20 18 0,000 0,02471813 0,03806321 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02471813 0,03804715 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02471813 0,0380311 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02471813 0,03801507 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02471813 0,03799905 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02471813 0,03798304 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02471813 0,03796705 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02471813 0,03795107 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02471813 0,0379351 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02471813 0,03791915 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02607399 0,03998231 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02607399 0,03996551 ! proteasome core complex GO:0005839 20 19 0,000 0,02607399 0,03994873 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02607399 0,03993196 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02607399 0,0399152 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02607399 0,03989846 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02607399 0,03988173 GO:0032409|regulation of transporter activity, ! regulation of survival gene product expression GO:0045884 23 19 0,000 0,02607399 0,03986501 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02607399 0,03984831 ! lysosome organization GO:0007040 20 19 0,000 0,02607399 0,03983162 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02607399 0,03981495 ! central nervous system neuron development GO:0021954 21 19 0,000 0,02607399 0,03979829 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02607399 0,03978165 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02607399 0,03976502 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02607399 0,0397484 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02607399 0,0397318 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02607399 0,03971521 ! peptide cross-linking GO:0018149 23 19 0,000 0,02607399 0,03969863 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02607399 0,03968207 ! beta-catenin binding GO:0008013 23 19 0,000 0,02607399 0,03966552 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02607399 0,03964899 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02607399 0,03963247 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02607399 0,03961596 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02607399 0,03959947 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02607399 0,03958299 ! vitamin transport GO:0051180 21 19 0,000 0,02607399 0,03956652 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02607399 0,03955007 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02607399 0,03953363 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02607399 0,03951721 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02607399 0,0395008 ! retinoid binding GO:0005501 19 19 0,000 0,02607399 0,0394844 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02607399 0,03946802 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02607399 0,03945165 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02607399 0,03943529 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02607399 0,03941895 ! gluconeogenesis GO:0006094 23 19 0,000 0,02607399 0,03940262 ! microtubule-based transport GO:0010970 20 19 0,000 0,02607399 0,0393863 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02607399 0,03937 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02607399 0,03935371 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02607399 0,03933744 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02607399 0,03932117 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02607399 0,03930493 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02607399 0,03928869 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02607399 0,03927247 ! acetylcholine binding GO:0042166 20 19 0,000 0,02607399 0,03925626 ! heme metabolic process GO:0042168 20 19 0,000 0,02607399 0,03924007 ! SH2 domain binding GO:0042169 25 19 0,000 0,02607399 0,03922388 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02607399 0,03920772 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02607399 0,03919156 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02607399 0,03917542 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02607399 0,03915929 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02607399 0,03914318 ! body fluid secretion GO:0007589 21 19 0,000 0,02607399 0,03912708 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02607399 0,03911099 ! secretory granule membrane GO:0030667 21 19 0,000 0,02607399 0,03909491 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02607399 0,03907885 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02607399 0,0390628 ! peptidase activator activity GO:0016504 21 19 0,000 0,02607399 0,03904677 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02607399 0,03903074 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02607399 0,03901473 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02607399 0,03899874 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02607399 0,03898275 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02607399 0,03896678 ! chaperone binding GO:0051087 21 20 0,000 0,02742804 0,04097358 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02742804 0,04095681 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02742804 0,04094005 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02742804 0,04092331 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02742804 0,04090658 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02742804 0,04088986 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02742804 0,04087316 ! ovarian follicle development GO:0001541 21 20 0,000 0,02742804 0,04085647 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02742804 0,04083979 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02742804 0,04082313 ! diencephalon development GO:0021536 22 20 0,000 0,02742804 0,04080648 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02742804 0,04078985 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02742804 0,04077322 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02742804 0,04075662 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02742804 0,04074002 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02742804 0,04072344 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02742804 0,04070687 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02742804 0,04069032 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02742804 0,04067378 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02742804 0,04065725 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02742804 0,04064074 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02742804 0,04062424 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02742804 0,04060775 ! initiation of viral infection GO:0019059 22 20 0,000 0,02742804 0,04059127 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02742804 0,04057481 ! heterochromatin GO:0000792 20 20 0,000 0,02742804 0,04055837 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02742804 0,04054193 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02742804 0,04052551 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02742804 0,04050911 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02742804 0,04049271 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02742804 0,04047633 ! visual behavior GO:0007632 34 20 0,000 0,02742804 0,04045996 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02742804 0,04044361 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02742804 0,04042727 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02742804 0,04041094 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02742804 0,04039463 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02742804 0,04037833 ! cell structure disassembly during apoptosis GO:0006921 31 20 0,000 0,02742804 0,04036204 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02742804 0,04034576 ! rRNA binding GO:0019843 22 20 0,000 0,02742804 0,0403295 ! cytolysis GO:0019835 22 20 0,000 0,02742804 0,04031325 ! renal system process GO:0003014 22 20 0,000 0,02742804 0,04029702 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02742804 0,04028079 ! fatty acid transport GO:0015908 23 20 0,000 0,02742804 0,04026458 ! transaminase activity GO:0008483 22 20 0,000 0,02742804 0,04024839 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02742804 0,0402322 ! collagen catabolic process GO:0030574 21 20 0,000 0,02742804 0,04021603 ! microvillus GO:0005902 25 20 0,000 0,02742804 0,04019988 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02742804 0,04018373 ! connexon complex GO:0005922 23 20 0,000 0,02742804 0,0401676 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02878028 0,042131 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02878028 0,0421141 ! translational initiation GO:0006413 21 21 0,000 0,02878028 0,04209722 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02878028 0,04208034 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02878028 0,04206349 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02878028 0,04204664 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02878028 0,04202981 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02878028 0,04201299 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02878028 0,04199618 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02878028 0,04197939 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02878028 0,04196261 ! regeneration GO:0031099 24 21 0,000 0,02878028 0,04194585 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02878028 0,0419291 ! cellular response to starvation GO:0009267 22 21 0,000 0,02878028 0,04191236 ! peroxisome organization GO:0007031 22 21 0,000 0,02878028 0,04189563 ! vacuole organization GO:0007033 23 21 0,000 0,02878028 0,04187892 ! apoptotic nuclear changes GO:0030262 24 21 0,000 0,02878028 0,04186222 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02878028 0,04184554 ! neural crest cell development GO:0014032 24 21 0,000 0,02878028 0,04182887 GO:0014033|neural crest cell differentiation, ! regulation of protein binding GO:0043393 25 21 0,000 0,02878028 0,04181221 ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02878028 0,04179557 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02878028 0,04177893 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02878028 0,04176231 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02878028 0,04174571 ! pallium development GO:0021543 22 21 0,000 0,02878028 0,04172912 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02878028 0,04171254 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02878028 0,04169597 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02878028 0,04167942 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02878028 0,04166288 ! cyclase activity GO:0009975 22 21 0,000 0,02878028 0,04164635 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02878028 0,04162984 ! gut development GO:0048565 23 21 0,000 0,02878028 0,04161334 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02878028 0,04159685 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02878028 0,04158038 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02878028 0,04156392 ! cortical actin cytoskeleton GO:0030864 21 21 0,000 0,02878028 0,04154747 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02878028 0,04153104 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02878028 0,04151461 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02878028 0,04149821 ! axis specification GO:0009798 25 21 0,000 0,02878028 0,04148181 ! response to alkaloid GO:0043279 27 21 0,000 0,02878028 0,04146543 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02878028 0,04144906 ! response to ethanol GO:0045471 28 21 0,000 0,02878028 0,0414327 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02878028 0,04141635 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02878028 0,04140002 ! vesicle targeting GO:0006903 22 21 0,000 0,02878028 0,04138371 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02878028 0,0413674 ! SNARE binding GO:0000149 24 21 0,000 0,02878028 0,04135111 ! interaction with host GO:0051701 26 21 0,000 0,02878028 0,04133483 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02878028 0,04131856 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02878028 0,04130231 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02878028 0,04128606 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02878028 0,04126983 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02878028 0,04125362 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02878028 0,04123742 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02878028 0,04122122 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02878028 0,04120505 ! insulin receptor binding GO:0005158 25 21 0,000 0,02878028 0,04118888 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02878028 0,04117273 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02878028 0,04115659 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,03013071 0,04307086 ! metencephalon development GO:0022037 25 22 0,000 0,03013071 0,04305399 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,03013071 0,04303713 ! hormone secretion GO:0046879 28 22 0,000 0,03013071 0,04302029 ! vesicle docking GO:0048278 24 22 0,000 0,03013071 0,04300346 ! muscle myosin complex GO:0005859 23 22 0,000 0,03013071 0,04298664 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,03013071 0,04296983 ! actomyosin structure organization GO:0031032 24 22 0,000 0,03013071 0,04295304 ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,03013071 0,04293626 ! sperm motility GO:0030317 23 22 0,000 0,03013071 0,0429195 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,03013071 0,04290275 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,03013071 0,04288601 ! vacuolar transport GO:0007034 22 22 0,000 0,03013071 0,04286928 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,03013071 0,04285257 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,03013071 0,04283587 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,03013071 0,04281918 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,03013071 0,0428025 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,03013071 0,04278584 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,03013071 0,0427692 ! PML body GO:0016605 25 22 0,000 0,03013071 0,04275256 ! barbed-end actin filament capping GO:0051016 24 22 0,000 0,03013071 0,04273594 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 27 22 0,000 0,03013071 0,04271933 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,03013071 0,04270273 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,03013071 0,04268615 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,03013071 0,04266958 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,03013071 0,04265302 ! deacetylase activity GO:0019213 23 22 0,000 0,03013071 0,04263648 ! pentose metabolic process GO:0019321 23 22 0,000 0,03013071 0,04261994 ! collagen fibril organization GO:0030199 32 22 0,000 0,03013071 0,04260342 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,03013071 0,04258692 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,03013071 0,04257042 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,03013071 0,04255394 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,03013071 0,04253747 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,03013071 0,04252102 ! positive regulation of behavior GO:0048520 24 22 0,000 0,03013071 0,04250458 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,03013071 0,04248815 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,03013071 0,04247173 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,03013071 0,04245532 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,03013071 0,04243893 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,03013071 0,04242255 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,03013071 0,04240619 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 0,000 0,03013071 0,04238983 ! glycerol metabolic process GO:0006071 24 22 0,000 0,03013071 0,04237349 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 0,000 0,03013071 0,04235716 ! nuclear chromatin GO:0000790 23 22 0,000 0,03013071 0,04234084 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,03013071 0,04232454 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,03013071 0,04230825 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,03013071 0,04229197 ! sterol binding GO:0032934 24 22 0,000 0,03013071 0,0422757 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,03013071 0,04225945 ! digestive system process GO:0022600 25 22 0,000 0,03013071 0,04224321 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,03013071 0,04222698 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,03013071 0,04221077 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,03013071 0,04219456 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,03013071 0,04217837 ! base-excision repair GO:0006284 33 22 0,000 0,03013071 0,04216219 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,03013071 0,04214602 ! DNA modification GO:0006304 25 22 0,000 0,03013071 0,04212987 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,03013071 0,04211373 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,03013071 0,0420976 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,03013071 0,04208148 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,03013071 0,04206538 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,03013071 0,04204929 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,03013071 0,04203321 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,03013071 0,04201714 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,03013071 0,04200108 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,03147934 0,04386425 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,03147934 0,04384751 ! leukocyte adhesion GO:0007159 26 23 0,000 0,03147934 0,04383077 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,03147934 0,04381405 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,03147934 0,04379734 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,03147934 0,04378064 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,03147934 0,04376396 ! ureteric bud development GO:0001657 24 23 0,000 0,03147934 0,04374728 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,03147934 0,04373062 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,03147934 0,04371398 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,03147934 0,04369734 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,03147934 0,04368072 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,03147934 0,04366411 ! deaminase activity GO:0019239 24 23 0,000 0,03147934 0,04364752 ! sensory perception of pain GO:0019233 26 23 0,000 0,03147934 0,04363093 ! lipid kinase activity GO:0001727 26 23 0,000 0,03147934 0,04361436 ! platelet activation GO:0030168 27 23 0,000 0,03147934 0,04359781 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,03147934 0,04358126 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,03147934 0,04356473 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,03147934 0,04354821 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,03147934 0,0435317 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,03147934 0,0435152 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,03147934 0,04349872 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,03147934 0,04348225 ! cell surface binding GO:0043498 28 23 0,000 0,03147934 0,04346579 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,03147934 0,04344935 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,03147934 0,04343291 ! regulation of glucose import GO:0046324 28 23 0,000 0,03147934 0,04341649 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,03147934 0,04340008 ! alditol metabolic process GO:0019400 25 23 0,000 0,03147934 0,04338369 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,03147934 0,0433673 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,03147934 0,04335093 ! zinc ion transport GO:0006829 26 23 0,000 0,03147934 0,04333457 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,03147934 0,04331823 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,03147934 0,04330189 ! sex determination GO:0007530 25 23 0,000 0,03147934 0,04328557 ! phosphate binding GO:0042301 25 23 0,000 0,03147934 0,04326926 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,03147934 0,04325296 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,03147934 0,04323668 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,03147934 0,04322041 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,03147934 0,04320415 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,03147934 0,0431879 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,03147934 0,04317166 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,03147934 0,04315544 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,03147934 0,04313923 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,03147934 0,04312303 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,03147934 0,04310684 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,03147934 0,04309066 ! leukocyte proliferation GO:0070661 26 23 0,000 0,03147934 0,0430745 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,03147934 0,04305835 ! growth cone GO:0030426 27 24 0,000 0,03282616 0,04488374 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,03282616 0,04486693 ! actin filament GO:0005884 26 24 0,000 0,03282616 0,04485012 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,03282616 0,04483333 ! pancreas development GO:0031016 27 24 0,000 0,03282616 0,04481655 ! calcium channel complex GO:0034704 31 24 0,000 0,03282616 0,04479979 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,03282616 0,04478303 ! negative regulation of cell development GO:0010721 30 24 0,000 0,03282616 0,04476629 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,03282616 0,04474956 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,03282616 0,04473285 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,03282616 0,04471614 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,03282616 0,04469945 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,03282616 0,04468277 ! Rho GTPase binding GO:0017048 36 24 0,000 0,03282616 0,0446661 ! regulation of glucose transport GO:0010827 29 24 0,000 0,03282616 0,04464945 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,03282616 0,04463281 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,03282616 0,04461618 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,03282616 0,04459956 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,03282616 0,04458296 ! protein stabilization GO:0050821 24 24 0,000 0,03282616 0,04456637 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,03282616 0,04454979 ! embryonic pattern specification GO:0009880 29 24 0,000 0,03282616 0,04453322 ! negative regulation of actin filament depolymerization GO:0030835 26 24 0,000 0,03282616 0,04451666 ! RNA polymerase complex GO:0030880 25 24 0,000 0,03282616 0,04450012 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,03282616 0,04448359 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,03282616 0,04446707 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,03282616 0,04445057 ! chemokine binding GO:0019956 26 24 0,000 0,03282616 0,04443407 ! catechol metabolic process GO:0009712 29 24 0,000 0,03282616 0,04441759 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,03282616 0,04440112 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,03282616 0,04438467 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,03282616 0,04436822 ! cell aging GO:0007569 47 24 0,000 0,03282616 0,04435179 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,03282616 0,04433537 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,03282616 0,04431896 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,03282616 0,04430256 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,03282616 0,04428618 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,03282616 0,04426981 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,03282616 0,04425345 ! caspase regulator activity GO:0043028 26 24 0,000 0,03282616 0,0442371 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,03282616 0,04422076 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 0,000 0,03282616 0,04420444 ! selenium binding GO:0008430 24 24 0,000 0,03282616 0,04418813 ! spindle pole GO:0000922 35 24 0,000 0,03282616 0,04417183 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,03282616 0,04415554 ! phenol metabolic process GO:0018958 31 25 0,000 0,03417118 0,04594783 ! protein amino acid acylation GO:0043543 28 25 0,000 0,03417118 0,0459309 ! aromatase activity GO:0070330 28 25 0,000 0,03417118 0,04591398 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,03417118 0,04589708 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,03417118 0,04588019 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,03417118 0,04586331 ! response to starvation GO:0042594 26 25 0,000 0,03417118 0,04584644 ! dynein complex GO:0030286 28 25 0,000 0,03417118 0,04582958 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,03417118 0,04581274 ! regulation of behavior GO:0050795 27 25 0,000 0,03417118 0,04579591 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,03417118 0,04577909 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,03417118 0,04576229 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,03417118 0,04574549 ! hormone transport GO:0009914 31 25 0,000 0,03417118 0,04572871 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,03417118 0,04571194 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,03417118 0,04569519 ! regulation of coagulation GO:0050818 28 25 0,000 0,03417118 0,04567844 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03417118 0,04566171 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,03417118 0,04564499 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,03417118 0,04562828 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,03417118 0,04561159 ! molting cycle process GO:0022404 28 25 0,000 0,03417118 0,0455949 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,03417118 0,04557823 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,03417118 0,04556157 ! phototransduction GO:0007602 27 25 0,000 0,03417118 0,04554493 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,03417118 0,04552829 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,03417118 0,04551167 ! protein phosphatase binding GO:0019903 27 25 0,000 0,03417118 0,04549506 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,03417118 0,04547846 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,03417118 0,04546188 ! autophagy GO:0006914 28 25 0,000 0,03417118 0,0454453 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,03417118 0,04542874 ! response to ionizing radiation GO:0010212 37 25 0,000 0,03417118 0,04541219 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,03417118 0,04539565 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,0355144 0,04716292 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,0355144 0,04714576 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 0,000 0,0355144 0,04712861 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,0355144 0,04711147 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,0355144 0,04709434 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,0355144 0,04707723 ! hair cycle GO:0042633 29 26 0,000 0,0355144 0,04706013 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,0355144 0,04704304 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,0355144 0,04702597 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,0355144 0,0470089 ! early endosome membrane GO:0031901 31 26 0,000 0,0355144 0,04699185 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,0355144 0,04697482 ! iron ion homeostasis GO:0055072 29 26 0,000 0,0355144 0,04695779 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,0355144 0,04694078 ! PDZ domain binding GO:0030165 28 26 0,000 0,0355144 0,04692377 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,0355144 0,04690679 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,0355144 0,04688981 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,0355144 0,04687284 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,0355144 0,04685589 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,0355144 0,04683895 ! fatty acid binding GO:0005504 28 26 0,000 0,0355144 0,04682202 ! blastocyst development GO:0001824 27 26 0,000 0,0355144 0,04680511 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,0355144 0,04678821 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,0355144 0,04677131 GO:0004402|histone acetyltransferase activity, ! negative regulation of protein polymerization GO:0032272 37 26 0,000 0,0355144 0,04675444 ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,0355144 0,04673757 ! regulation of actin filament depolymerization GO:0030834 28 26 0,000 0,0355144 0,04672071 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,0355144 0,04670387 ! iron ion transport GO:0006826 33 26 0,000 0,0355144 0,04668704 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,0355144 0,04667022 ! glucose transport GO:0015758 27 26 0,000 0,0355144 0,04665342 ! insulin receptor signaling pathway GO:0008286 34 26 0,000 0,0355144 0,04663662 ! spinal cord development GO:0021510 30 26 0,000 0,0355144 0,04661984 ! histone deacetylase complex GO:0000118 29 26 0,000 0,0355144 0,04660307 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,0355144 0,04658631 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,0355144 0,04656957 ! RNA helicase activity GO:0003724 46 26 0,000 0,0355144 0,04655284 ! brush border GO:0005903 30 26 0,000 0,0355144 0,04653611 ! gap junction GO:0005921 29 26 0,000 0,0355144 0,0465194 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,0355144 0,04650271 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,03685583 0,04824186 ! RNA export from nucleus GO:0006405 31 27 0,000 0,03685583 0,04822456 ! mRNA catabolic process GO:0006402 31 27 0,000 0,03685583 0,04820727 ! myelination GO:0042552 31 27 0,000 0,03685583 0,04818999 ! trans-Golgi network GO:0005802 31 27 0,000 0,03685583 0,04817272 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,03685583 0,04815547 ! spliceosomal snRNP biogenesis GO:0000387 29 27 0,000 0,03685583 0,04813823 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,03685583 0,048121 ! vasculogenesis GO:0001570 32 27 0,000 0,03685583 0,04810378 ! hexose transport GO:0008645 28 27 0,000 0,03685583 0,04808658 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,03685583 0,04806938 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,03685583 0,0480522 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,03685583 0,04803504 ! cell fate determination GO:0001709 29 27 0,000 0,03685583 0,04801788 ! lipid oxidation GO:0034440 29 27 0,000 0,03685583 0,04800074 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,03685583 0,04798361 ! collagen binding GO:0005518 29 27 0,000 0,03685583 0,04796649 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,03685583 0,04794938 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,03685583 0,04793229 ! liver development GO:0001889 33 27 0,000 0,03685583 0,0479152 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,03685583 0,04789814 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,03685583 0,04788108 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,03685583 0,04786403 ! membrane docking GO:0022406 29 27 0,000 0,03685583 0,047847 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,03685583 0,04782998 GO:0050908|detection of light stimulus involved in visual perception, ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,03685583 0,04781297 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,03685583 0,04779597 ! phospholipid transport GO:0015914 29 27 0,000 0,03685583 0,04777899 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,03685583 0,04776201 ! aminopeptidase activity GO:0004177 33 27 0,000 0,03685583 0,04774505 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,03685583 0,0477281 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,03685583 0,04771117 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,03685583 0,04769424 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,03685583 0,04767733 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,03685583 0,04766043 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03819546 0,04937528 ! Golgi stack GO:0005795 30 28 0,000 0,03819546 0,04935779 ! male gonad development GO:0008584 32 28 0,000 0,03819546 0,04934031 ! lipoprotein binding GO:0008034 31 28 0,000 0,03819546 0,04932285 ! mesoderm formation GO:0001707 34 28 0,000 0,03819546 0,04930539 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03819546 0,04928795 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03819546 0,04927052 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03819546 0,04925311 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03819546 0,0492357 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03819546 0,04921831 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03819546 0,04920093 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03819546 0,04918357 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03819546 0,04916621 ! tissue homeostasis GO:0001894 31 28 0,000 0,03819546 0,04914887 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03819546 0,04913154 ! negative regulation of protein complex assembly GO:0031333 39 28 0,000 0,03819546 0,04911422 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03819546 0,04909691 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03819546 0,04907962 ! post-embryonic development GO:0009791 32 28 0,000 0,03819546 0,04906234 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03819546 0,04904507 ! detection of visible light GO:0009584 30 28 0,000 0,03819546 0,04902781 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03819546 0,04901057 ! receptor regulator activity GO:0030545 31 28 0,000 0,03819546 0,04899333 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03819546 0,04897611 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03819546 0,04895891 ! response to heat GO:0009408 33 28 0,000 0,03819546 0,04894171 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03819546 0,04892452 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,0395333 0,05062039 ! hormone binding GO:0042562 31 29 0,000 0,0395333 0,05060263 ! striated muscle cell differentiation GO:0051146 42 29 0,000 0,0395333 0,05058488 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,0395333 0,05056714 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,0395333 0,05054942 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,0395333 0,05053171 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,0395333 0,05051401 ! ceramide metabolic process GO:0006672 29 29 0,000 0,0395333 0,05049632 ! replication fork GO:0005657 42 29 0,000 0,0395333 0,05047864 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,0395333 0,05046098 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,0395333 0,05044333 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,0395333 0,05042569 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,0395333 0,05040807 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,0395333 0,05039046 ! regulation of pH GO:0006885 30 29 0,000 0,0395333 0,05037286 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,0395333 0,05035527 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,0395333 0,05033769 ! phospholipase C activity GO:0004629 43 29 0,000 0,0395333 0,05032013 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,0395333 0,05030258 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,0395333 0,05028504 ! sodium channel activity GO:0005272 33 29 0,000 0,0395333 0,05026751 ! sarcoplasm GO:0016528 31 29 0,000 0,0395333 0,05025 ! detection of light stimulus GO:0009583 31 29 0,000 0,0395333 0,05023249 ! spermatid development GO:0007286 30 29 0,000 0,0395333 0,050215 ! DNA polymerase activity GO:0034061 34 29 0,000 0,0395333 0,05019752 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,0395333 0,05018006 ! sarcolemma GO:0042383 30 29 0,000 0,0395333 0,0501626 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,0395333 0,05014516 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,0395333 0,05012773 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,0395333 0,05011032 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,04086935 0,05178583 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,04086935 0,05176785 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,04086935 0,05174988 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,04086935 0,05173192 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,04086935 0,05171398 ! scavenger receptor activity GO:0005044 39 30 0,000 0,04086935 0,05169605 ! spliceosome assembly GO:0000245 34 30 0,000 0,04086935 0,05167813 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,04086935 0,05166022 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,04086935 0,05164233 ! metanephros development GO:0001656 31 30 0,000 0,04086935 0,05162445 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,04086935 0,05160658 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,04086935 0,05158872 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,04086935 0,05157088 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,04086935 0,05155304 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,04086935 0,05153522 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,04086935 0,05151742 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,04086935 0,05149962 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,04086935 0,05148184 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,04086935 0,05146407 ! cortical cytoskeleton GO:0030863 33 30 0,000 0,04086935 0,05144631 ! protein-lipid complex GO:0032994 41 30 0,000 0,04086935 0,05142856 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,04086935 0,05141083 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,04086935 0,05139311 ! phosphatase binding GO:0019902 34 30 0,000 0,04086935 0,0513754 ! acute-phase response GO:0006953 44 30 0,000 0,04086935 0,0513577 ! segmentation GO:0035282 37 30 0,000 0,04086935 0,05134001 ! response to toxin GO:0009636 33 30 0,000 0,04086935 0,05132234 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,04086935 0,05130468 ! antigen binding GO:0003823 33 30 0,000 0,04086935 0,05128703 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,04086935 0,0512694 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,04086935 0,05125177 ! ensheathment of neurons GO:0007272 35 30 0,000 0,04086935 0,05123416 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,04086935 0,05121656 ! vesicle localization GO:0051648 31 30 0,000 0,04086935 0,05119897 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,04220362 0,05285232 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,04220362 0,05283418 ! acrosomal vesicle GO:0001669 34 31 0,000 0,04220362 0,05281605 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04220362 0,05279794 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,04220362 0,05277984 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,04220362 0,05276175 ! formation of primary germ layer GO:0001704 37 31 0,000 0,04220362 0,05274368 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,04220362 0,05272562 ! endocytic vesicle GO:0030139 33 31 0,000 0,04220362 0,05270757 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,04220362 0,05268953 ! spermatid differentiation GO:0048515 32 31 0,000 0,04220362 0,0526715 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,04220362 0,05265349 ! neuron fate commitment GO:0048663 44 31 0,000 0,04220362 0,05263549 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,04220362 0,0526175 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,04220362 0,05259952 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,04220362 0,05258156 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,04220362 0,0525636 ! cell junction assembly GO:0034329 36 31 0,000 0,04220362 0,05254566 ! drug binding GO:0008144 34 31 0,000 0,04220362 0,05252774 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,04220362 0,05250982 ! peptide transport GO:0015833 36 31 0,000 0,04220362 0,05249192 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,04220362 0,05247403 ! peripheral nervous system development GO:0007422 35 31 0,000 0,04220362 0,05245615 ! I band GO:0031674 34 31 0,000 0,04220362 0,05243828 ! BMP signaling pathway GO:0030509 33 31 0,000 0,04220362 0,05242043 ! adult locomotory behavior GO:0008344 37 31 0,000 0,04220362 0,05240259 ! gene silencing GO:0016458 33 31 0,000 0,04220362 0,05238476 ! negative regulation of secretion GO:0051048 37 32 0,000 0,0435361 0,0540203 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,0435361 0,05400193 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,0435361 0,05398358 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,0435361 0,05396523 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,0435361 0,0539469 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,0435361 0,05392858 ! vesicle coat GO:0030120 39 32 0,000 0,0435361 0,05391028 ! cytokine production GO:0001816 32 32 0,000 0,0435361 0,05389199 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,0435361 0,0538737 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,0435361 0,05385544 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,0435361 0,05383718 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,0435361 0,05381894 ! oxygen binding GO:0019825 33 32 0,000 0,0435361 0,05380071 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,0435361 0,05378249 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,0435361 0,05376428 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,0435361 0,05374609 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,0435361 0,0537279 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,04486679 0,05535139 ! DNA helicase activity GO:0003678 55 33 0,000 0,04486679 0,05533268 ! neural tube development GO:0021915 37 33 0,000 0,04486679 0,05531398 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,04486679 0,05529529 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,04486679 0,05527662 ! organelle envelope lumen GO:0031970 46 33 0,000 0,04486679 0,05525796 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,04486679 0,05523931 ! NAD or NADH binding GO:0051287 36 33 0,000 0,04486679 0,05522067 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,04486679 0,05520205 ! B cell differentiation GO:0030183 37 33 0,000 0,04486679 0,05518343 ! aerobic respiration GO:0009060 35 33 0,000 0,04486679 0,05516483 ! embryonic organ development GO:0048568 41 33 0,000 0,04486679 0,05514625 ! placenta development GO:0001890 39 33 0,000 0,04486679 0,05512767 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,04486679 0,05510911 ! tissue remodeling GO:0048771 37 33 0,000 0,04486679 0,05509056 ! flagellum GO:0019861 34 33 0,000 0,04486679 0,05507203 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,04486679 0,0550535 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,04486679 0,05503499 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,04486679 0,05501649 ! odontogenesis GO:0042476 39 34 0,000 0,04619571 0,056627 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04619571 0,05660798 ! lipid homeostasis GO:0055088 37 34 0,000 0,04619571 0,05658897 ! telencephalon development GO:0021537 36 34 0,000 0,04619571 0,05656997 ! clathrin coat GO:0030118 41 34 0,000 0,04619571 0,05655099 ! cell growth GO:0016049 36 34 0,000 0,04619571 0,05653202 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,04619571 0,05651306 ! learning GO:0007612 51 34 0,000 0,04619571 0,05649412 ! keratinization GO:0031424 40 34 0,000 0,04619571 0,05647518 ! ovulation cycle process GO:0022602 35 34 0,000 0,04619571 0,05645627 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,04619571 0,05643736 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,04619571 0,05641846 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,04619571 0,05639958 ! amino acid binding GO:0016597 40 34 0,000 0,04619571 0,05638071 ! regulation of protein stability GO:0031647 35 34 0,000 0,04619571 0,05636186 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,04619571 0,05634301 ! glycogen metabolic process GO:0005977 48 34 0,000 0,04619571 0,05632418 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,04619571 0,05630536 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,04619571 0,05628656 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,04619571 0,05626776 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,04752285 0,05786494 GO:0090047|positive regulation of transcription regulator activity, ! inner ear morphogenesis GO:0042472 46 35 0,000 0,04752285 0,05784563 ! MHC protein complex GO:0042611 50 35 0,000 0,04752285 0,05782634 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,04752285 0,05780705 ! vesicle lumen GO:0031983 38 35 0,000 0,04752285 0,05778778 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,04752285 0,05776853 ! mesenchymal cell development GO:0014031 40 35 0,000 0,04752285 0,05774928 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,04752285 0,05773005 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,04752285 0,05771084 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,04752285 0,05769163 ! regulation of proteolysis GO:0030162 37 35 0,000 0,04752285 0,05767244 ! ovulation cycle GO:0042698 37 35 0,000 0,04752285 0,05765326 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,04752285 0,05763409 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,04752285 0,05761494 ! collagen GO:0005581 54 35 0,000 0,04752285 0,0575958 ! glucan metabolic process GO:0044042 49 35 0,000 0,04752285 0,05757667 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,04752285 0,05755755 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,04752285 0,05753845 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,04752285 0,05751936 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,04752285 0,05750028 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,04752285 0,05748122 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,04752285 0,05746217 ! maintenance of protein location GO:0045185 45 35 0,000 0,04752285 0,05744313 ! polyol metabolic process GO:0019751 46 35 0,000 0,04752285 0,0574241 ! cytokinesis GO:0000910 38 35 0,000 0,04752285 0,05740508 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,04752285 0,05738608 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,04884821 0,058967 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,04884821 0,05894749 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,04884821 0,058928 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,04884821 0,05890852 ! SMAD binding GO:0046332 39 36 0,000 0,04884821 0,05888905 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,04884821 0,0588696 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,04884821 0,05885016 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,04884821 0,05883073 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,04884821 0,05881131 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,04884821 0,05879191 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,04884821 0,05877252 ! nucleus organization GO:0006997 42 36 0,000 0,04884821 0,05875314 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,04884821 0,05873378 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,04884821 0,05871442 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,04884821 0,05869508 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,04884821 0,05867576 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,04884821 0,05865644 ! maintenance of location in cell GO:0051651 38 36 0,000 0,04884821 0,05863714 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,0501718 0,06020616 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,0501718 0,06018636 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,0501718 0,06016658 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,0501718 0,06014681 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,0501718 0,06012705 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,0501718 0,0601073 ! endoribonuclease activity GO:0004521 48 37 0,000 0,0501718 0,06008757 ! hindbrain development GO:0030902 43 37 0,000 0,0501718 0,06006785 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,0501718 0,06004814 ! pigmentation GO:0043473 51 37 0,000 0,0501718 0,06002845 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,0501718 0,06000876 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,0501718 0,0599891 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,0501718 0,05996944 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,0501718 0,0599498 ! sensory perception of taste GO:0050909 37 37 0,000 0,0501718 0,05993017 ! skeletal muscle fiber development GO:0048741 41 37 0,000 0,0501718 0,05991055 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,0501718 0,05989095 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,0501718 0,05987135 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,0501718 0,05985178 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,0501718 0,05983221 ! coated pit GO:0005905 44 37 0,000 0,0501718 0,05981266 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,05149362 0,06136842 ! regulation of translational initiation GO:0006446 50 38 0,000 0,05149362 0,06134838 ! negative regulation of binding GO:0051100 44 38 0,000 0,05149362 0,06132835 ! organic ether metabolic process GO:0018904 50 38 0,000 0,05149362 0,06130833 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,05149362 0,06128833 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,05149362 0,06126834 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,05149362 0,06124836 ! hydro-lyase activity GO:0016836 44 38 0,000 0,05149362 0,0612284 ! synapse organization GO:0050808 43 38 0,000 0,05149362 0,06120845 ! viral infectious cycle GO:0019058 40 38 0,000 0,05149362 0,06118851 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,05149362 0,06116859 ! negative regulation of protein complex disassembly GO:0043242 42 38 0,000 0,05149362 0,06114867 ! organic anion transport GO:0015711 42 38 0,000 0,05149362 0,06112877 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,05149362 0,06110889 ! monosaccharide binding GO:0048029 41 38 0,000 0,05149362 0,06108902 ! muscle fiber development GO:0048747 42 38 0,000 0,05149362 0,06106916 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,05149362 0,06104931 ! phagocytosis GO:0006909 44 38 0,000 0,05149362 0,06102948 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,05149362 0,06100965 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,05149362 0,06098985 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,05149362 0,06097005 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,05149362 0,06095027 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,05149362 0,0609305 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,05149362 0,06091074 ! cellular response to insulin stimulus GO:0032869 47 38 0,000 0,05149362 0,060891 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,05281367 0,06243171 ! induction of apoptosis by extracellular signals GO:0008624 44 39 0,000 0,05281367 0,06241149 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,05281367 0,06239128 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,05281367 0,06237108 ! T cell differentiation GO:0030217 64 39 0,000 0,05281367 0,0623509 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,05281367 0,06233072 ! cell fate specification GO:0001708 55 39 0,000 0,05281367 0,06231056 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,05281367 0,06229042 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,05281367 0,06227029 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,05281367 0,06225017 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,05281367 0,06223006 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,05281367 0,06220997 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,05281367 0,06218989 ! amine receptor activity GO:0008227 48 39 0,000 0,05281367 0,06216982 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,05281367 0,06214976 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,05281367 0,06212972 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,05281367 0,06210969 ! pigment metabolic process GO:0042440 43 39 0,000 0,05281367 0,06208968 ! RNA modification GO:0009451 39 39 0,000 0,05281367 0,06206967 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,05413195 0,06359851 ! peroxisomal membrane GO:0005778 44 40 0,000 0,05413195 0,06357803 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,05413195 0,06355757 ! positive regulation of cell development GO:0010720 43 40 0,000 0,05413195 0,06353712 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,05413195 0,06351668 ! biopolymer methylation GO:0043414 45 40 0,000 0,05413195 0,06349626 ! neuron migration GO:0001764 43 40 0,000 0,05413195 0,06347585 ! regulation of protein secretion GO:0050708 45 40 0,000 0,05413195 0,06345545 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,05413195 0,06343507 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,05413195 0,0634147 ! regulation of actin filament polymerization GO:0030833 53 40 0,000 0,05413195 0,06339434 ! positive regulation of defense response GO:0031349 41 40 0,000 0,05413195 0,06337399 ! mammary gland development GO:0030879 47 40 0,000 0,05413195 0,06335366 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,05413195 0,06333334 ! neuropeptide binding GO:0042923 42 40 0,000 0,05413195 0,06331304 ! regulation of tube size GO:0035150 44 40 0,000 0,05413195 0,06329274 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,05413195 0,06327246 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,05413195 0,0632522 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,05413195 0,06323194 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,05413195 0,0632117 ! chromatin remodeling GO:0006338 44 40 0,000 0,05413195 0,06319148 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,05413195 0,06317126 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,05544847 0,06468693 ! Notch signaling pathway GO:0007219 46 41 0,000 0,05544847 0,06466625 ! peptide metabolic process GO:0006518 42 41 0,000 0,05544847 0,06464558 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,05544847 0,06462493 ! late endosome membrane GO:0031902 45 41 0,000 0,05544847 0,06460429 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,05544847 0,06458366 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,05544847 0,06456305 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,05544847 0,06454244 ! lamellipodium GO:0030027 56 41 0,000 0,05544847 0,06452186 ! glycolysis GO:0006096 43 41 0,000 0,05544847 0,06450128 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,05544847 0,06448072 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,05544847 0,06446017 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,05544847 0,06443964 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,05676323 0,06594658 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,05676323 0,06592558 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,05676323 0,0659046 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,05676323 0,06588363 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,05676323 0,06586268 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,05676323 0,06584173 ! nuclear export GO:0051168 46 42 0,000 0,05676323 0,06582081 ! developmental growth GO:0048589 45 42 0,000 0,05676323 0,06579989 ! structural constituent of muscle GO:0008307 46 42 0,000 0,05676323 0,06577899 ! mitochondrial transport GO:0006839 45 42 0,000 0,05676323 0,0657581 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,05676323 0,06573722 ! metal cluster binding GO:0051540 47 42 0,000 0,05676323 0,06571636 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,05676323 0,06569551 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,05676323 0,06567468 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,05676323 0,06565385 ! RNA catabolic process GO:0006401 49 43 0,000 0,05807622 0,06715121 ! ear morphogenesis GO:0042471 56 43 0,000 0,05807622 0,06712993 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,05807622 0,06710867 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,05807622 0,06708742 ! cell recognition GO:0008037 51 43 0,000 0,05807622 0,06706618 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,05807622 0,06704496 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,05807622 0,06702375 ! gliogenesis GO:0042063 46 43 0,000 0,05807622 0,06700255 ! endosome transport GO:0016197 48 43 0,000 0,05807622 0,06698137 ! striated muscle contraction GO:0006941 45 43 0,000 0,05807622 0,0669602 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,05807622 0,06693904 ! antioxidant activity GO:0016209 53 43 0,000 0,05807622 0,0669179 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,05807622 0,06689677 ! activation of caspase activity GO:0006919 60 43 0,000 0,05807622 0,06687565 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,05807622 0,06685455 ! histone modification GO:0016570 45 43 0,000 0,05807622 0,06683346 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,05807622 0,06681238 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,05938746 0,06829933 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,05938746 0,0682778 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,05938746 0,06825629 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,05938746 0,06823479 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,05938746 0,06821331 ! chemokine activity GO:0008009 48 44 0,000 0,05938746 0,06819184 ! ruffle GO:0001726 50 44 0,000 0,05938746 0,06817038 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,05938746 0,06814894 ! regulation of neuron apoptosis GO:0043523 58 44 0,000 0,05938746 0,06812751 ! cartilage development GO:0051216 48 44 0,000 0,05938746 0,06810609 ! membrane fusion GO:0006944 52 44 0,000 0,05938746 0,06808469 ! channel regulator activity GO:0016247 54 44 0,000 0,05938746 0,0680633 ! excretion GO:0007588 53 44 0,000 0,05938746 0,06804192 ! male sex differentiation GO:0046661 52 44 0,000 0,05938746 0,06802056 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,05938746 0,06799921 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,05938746 0,06797787 ! amino acid activation GO:0043038 45 44 0,000 0,05938746 0,06795655 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,05938746 0,06793524 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,06069695 0,06941143 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,06069695 0,06938968 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,06069695 0,06936794 ! organellar ribosome GO:0000313 46 45 0,000 0,06069695 0,06934622 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,06069695 0,0693245 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,06069695 0,06930281 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,06069695 0,06928112 ! transport vesicle GO:0030133 53 45 0,000 0,06069695 0,06925945 ! regulation of endocytosis GO:0030100 52 45 0,000 0,06069695 0,06923779 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,06069695 0,06921615 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! regulation of protein complex disassembly GO:0043244 49 45 0,000 0,06069695 0,06919452 ! nuclear matrix GO:0016363 56 45 0,000 0,06069695 0,0691729 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,06069695 0,0691513 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,06069695 0,06912971 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,06069695 0,06910814 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,06069695 0,06908657 ! coated vesicle membrane GO:0030662 52 45 0,000 0,06069695 0,06906502 ! covalent chromatin modification GO:0016569 47 45 0,000 0,06069695 0,06904349 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,06069695 0,06902197 ! synaptosome GO:0019717 50 45 0,000 0,06069695 0,06900046 ! chemokine receptor binding GO:0042379 50 45 0,000 0,06069695 0,06897896 ! regulation of action potential GO:0001508 56 46 0,000 0,06200468 0,07044319 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,06200468 0,07042125 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,06200468 0,07039934 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,06200468 0,07037743 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,06200468 0,07035554 ! methylation GO:0032259 51 46 0,000 0,06200468 0,07033367 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,06200468 0,0703118 ! regulation of ion transport GO:0043269 54 46 0,000 0,06200468 0,07028995 ! leukocyte migration GO:0050900 49 46 0,000 0,06200468 0,07026812 ! neuromuscular process GO:0050905 56 46 0,000 0,06200468 0,0702463 ! sulfotransferase activity GO:0008146 54 46 0,000 0,06200468 0,07022449 ! SH3/SH2 adaptor activity GO:0005070 52 46 0,000 0,06200468 0,07020269 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,06331066 0,0716591 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,06331066 0,07163688 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 0,000 0,06331066 0,07161466 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,06331066 0,07159246 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,06331066 0,07157028 ! regulation of protein polymerization GO:0032271 60 47 0,000 0,06331066 0,07154811 ! viral reproductive process GO:0022415 53 47 0,000 0,06331066 0,07152595 ! RNA elongation GO:0006354 52 47 0,000 0,06331066 0,0715038 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,06331066 0,07148167 ! mRNA binding GO:0003729 65 47 0,000 0,06331066 0,07145956 ! response to insulin stimulus GO:0032868 57 47 0,000 0,06331066 0,07143745 ! axon GO:0030424 53 48 0,000 0,06461489 0,07288656 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,06461489 0,07286403 ! proteasome complex GO:0000502 50 48 0,000 0,06461489 0,07284151 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,06461489 0,07281901 ! protein homooligomerization GO:0051260 63 48 0,000 0,06461489 0,07279652 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,06461489 0,07277404 ! kinetochore GO:0000776 69 48 0,000 0,06461489 0,07275158 ! positive regulation of caspase activity GO:0043280 65 48 0,000 0,06461489 0,07272913 GO:0010952|positive regulation of peptidase activity, ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,06461489 0,0727067 ! growth factor receptor binding GO:0070851 58 48 0,000 0,06461489 0,07268428 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,06461489 0,07266188 ! inner ear development GO:0048839 60 48 0,000 0,06461489 0,07263948 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,06461489 0,07261711 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,06461489 0,07259474 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,06461489 0,07257239 ! B cell mediated immunity GO:0019724 53 48 0,000 0,06461489 0,07255005 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,06461489 0,07252773 ! regulation of cell shape GO:0008360 55 48 0,000 0,06461489 0,07250542 ! protein N-terminus binding GO:0047485 57 48 0,000 0,06461489 0,07248313 ! establishment of organelle localization GO:0051656 58 48 0,000 0,06461489 0,07246084 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,06591738 0,07389877 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,06591738 0,07387607 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,06591738 0,07385338 ! response to temperature stimulus GO:0009266 57 49 0,000 0,06591738 0,0738307 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,06591738 0,07380804 ! lipid modification GO:0030258 55 49 0,000 0,06591738 0,07378539 ! synaptic vesicle GO:0008021 56 49 0,000 0,06591738 0,07376276 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,06591738 0,07374014 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,06591738 0,07371753 ! maintenance of location GO:0051235 62 49 0,000 0,06591738 0,07369494 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,06591738 0,07367236 ! regulation of actin filament length GO:0030832 62 49 0,000 0,06591738 0,0736498 ! nuclear periphery GO:0034399 60 49 0,000 0,06591738 0,07362725 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,06591738 0,07360471 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,06591738 0,07358219 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,06721812 0,07501123 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,06721812 0,07498829 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,06721812 0,07496536 ! glucose catabolic process GO:0006007 54 50 0,000 0,06721812 0,07494245 ! aging GO:0007568 92 50 0,000 0,06721812 0,07491955 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,06721812 0,07489667 ! heart morphogenesis GO:0003007 57 50 0,000 0,06721812 0,0748738 ! integrin binding GO:0005178 56 50 0,000 0,06721812 0,07485095 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,06721812 0,0748281 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,06851712 0,0762509 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,06851712 0,07622765 ! regulation of ossification GO:0030278 59 51 0,000 0,06851712 0,07620441 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,06851712 0,07618118 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,06851712 0,07615797 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,06851712 0,07613477 ! endocrine system development GO:0035270 55 51 0,000 0,06851712 0,07611159 ! germ cell development GO:0007281 56 51 0,000 0,06851712 0,07608842 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,06981438 0,07750543 ! regulation of cellular component size GO:0032535 66 52 0,000 0,06981438 0,07748185 ! carbohydrate transport GO:0008643 57 52 0,000 0,06981438 0,07745829 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,06981438 0,07743474 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,06981438 0,0774112 ! cell maturation GO:0048469 68 52 0,000 0,06981438 0,07738768 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,06981438 0,07736417 ! kidney development GO:0001822 55 52 0,000 0,06981438 0,07734068 ! cellular component disassembly GO:0022411 69 52 0,000 0,06981438 0,0773172 ! cell redox homeostasis GO:0045454 57 52 0,000 0,06981438 0,07729373 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,06981438 0,07727028 ! lipid transporter activity GO:0005319 58 52 0,000 0,06981438 0,07724685 ! cytokine receptor activity GO:0004896 54 52 0,000 0,06981438 0,07722343 ! antiporter activity GO:0015297 53 52 0,000 0,06981438 0,07720002 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,0711099 0,07860876 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,0711099 0,07858495 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,0711099 0,07856115 ! basement membrane GO:0005604 55 53 0,000 0,0711099 0,07853737 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,0711099 0,0785136 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,0711099 0,07848984 ! viral reproduction GO:0016032 59 53 0,000 0,0711099 0,0784661 ! chloride transport GO:0006821 60 53 0,000 0,0711099 0,07844237 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,0711099 0,07841866 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,0711099 0,07839496 ! regulation of DNA replication GO:0006275 75 53 0,000 0,0711099 0,07837128 ! DNA catabolic process GO:0006308 57 53 0,000 0,0711099 0,07834761 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,0711099 0,07832395 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,0711099 0,07830031 ! single fertilization GO:0007338 58 53 0,000 0,0711099 0,07827668 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,07240369 0,07967682 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,07240369 0,07965279 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,07240369 0,07962878 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,07240369 0,07960478 ! coated membrane GO:0048475 65 54 0,000 0,07240369 0,0795808 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,07240369 0,07955683 ! regulation of protein complex assembly GO:0043254 67 54 0,000 0,07240369 0,07953287 ! cellular defense response GO:0006968 61 54 0,000 0,07240369 0,07950893 ! gastrulation GO:0007369 62 54 0,000 0,07240369 0,079485 ! dendrite GO:0030425 60 55 0,000 0,07369575 0,08087909 ! regulation of mitosis GO:0007088 79 55 0,000 0,07369575 0,08085476 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,07369575 0,08083045 ! respiratory chain GO:0070469 57 55 0,000 0,07369575 0,08080616 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,07369575 0,08078188 ! extracellular matrix organization GO:0030198 77 55 0,000 0,07369575 0,08075761 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,07369575 0,08073336 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,07369575 0,08070912 ! translation initiation factor activity GO:0003743 66 55 0,000 0,07369575 0,0806849 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,07498607 0,08207296 ! heat shock protein binding GO:0031072 62 56 0,000 0,07498607 0,08204835 ! late endosome GO:0005770 60 56 0,000 0,07498607 0,08202374 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,07498607 0,08199916 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,07498607 0,08197458 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,07498607 0,08195003 ! ribonuclease activity GO:0004540 67 56 0,000 0,07498607 0,08192548 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,07498607 0,08190095 ! mesoderm development GO:0007498 67 56 0,000 0,07498607 0,08187644 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,07498607 0,08185194 ! antigen processing and presentation GO:0019882 73 56 0,000 0,07498607 0,08182746 ! proton transport GO:0015992 59 56 0,000 0,07498607 0,08180299 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,07627467 0,08318385 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,07627467 0,08315899 ! B cell activation GO:0042113 63 57 0,000 0,07627467 0,08313415 ! small ribosomal subunit GO:0015935 58 57 0,000 0,07627467 0,08310931 ! detection of external stimulus GO:0009581 64 57 0,000 0,07627467 0,0830845 ! occluding junction GO:0070160 75 58 0,000 0,07756154 0,08446104 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,07756154 0,08443584 ! response to nutrient GO:0007584 68 58 0,000 0,07756154 0,08441065 ! large ribosomal subunit GO:0015934 64 58 0,000 0,07756154 0,08438547 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,07756154 0,08436031 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,07756154 0,08433517 ! myosin complex GO:0016459 64 58 0,000 0,07756154 0,08431004 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,07884668 0,08568147 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,07884668 0,08565596 GO:0051213|dioxygenase activity, ! muscle cell differentiation GO:0042692 77 59 0,000 0,07884668 0,08563046 ! regulation of heart contraction GO:0008016 71 59 0,000 0,07884668 0,08560497 ! hexose catabolic process GO:0019320 64 59 0,000 0,07884668 0,0855795 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,07884668 0,08555405 ! cell projection assembly GO:0030031 79 59 0,000 0,07884668 0,08552861 ! appendage morphogenesis GO:0035107 68 59 0,000 0,07884668 0,08550318 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,07884668 0,08547777 ! fertilization GO:0009566 65 59 0,000 0,07884668 0,08545238 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,07884668 0,085427 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,07884668 0,08540163 ! adult behavior GO:0030534 72 59 0,000 0,07884668 0,08537628 ! organelle localization GO:0051640 70 59 0,000 0,07884668 0,08535095 ! positive regulation of secretion GO:0051047 66 60 0,000 0,08013011 0,08671452 ! molecular adaptor activity GO:0060090 73 60 0,000 0,08013011 0,0866888 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,08013011 0,0866631 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,08013011 0,08663741 ! copper ion binding GO:0005507 85 60 0,000 0,08013011 0,08661174 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,08013011 0,08658609 ! activation of immune response GO:0002253 72 60 0,000 0,08013011 0,08656045 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,08013011 0,08653482 ! appendage development GO:0048736 69 60 0,000 0,08013011 0,08650921 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,08013011 0,08648362 ! secondary metabolic process GO:0019748 67 60 0,000 0,08013011 0,08645804 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,08141181 0,08781499 ! ear development GO:0043583 76 61 0,000 0,08141181 0,08778903 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,08141181 0,08776309 ! learning or memory GO:0007611 79 61 0,000 0,08141181 0,08773716 ! Ras GTPase binding GO:0017016 78 61 0,000 0,08141181 0,08771125 ! camera-type eye development GO:0043010 69 61 0,000 0,08141181 0,08768535 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,08141181 0,08765947 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,0826918 0,08901142 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,0826918 0,08898516 ! lysosomal membrane GO:0005765 69 62 0,000 0,0826918 0,08895892 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,0826918 0,08893269 ! nuclear pore GO:0005643 79 62 0,000 0,0826918 0,08890648 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,0826918 0,08888029 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,0826918 0,08885411 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,0826918 0,08882794 ! chloride channel activity GO:0005254 72 62 0,000 0,0826918 0,08880179 ! cell soma GO:0043025 68 62 0,000 0,0826918 0,08877566 ! microtubule motor activity GO:0003777 94 62 0,000 0,0826918 0,08874954 ! focal adhesion GO:0005925 72 62 0,000 0,0826918 0,08872344 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,0826918 0,08869735 ! FAD binding GO:0050660 71 63 0,000 0,08397007 0,09004198 ! urogenital system development GO:0001655 75 63 0,000 0,08397007 0,09001552 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,08397007 0,08998908 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,08397007 0,08996265 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,08397007 0,08993624 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,08397007 0,08990984 ! regulation of immune effector process GO:0002697 81 63 0,000 0,08397007 0,08988346 ! respiratory tube development GO:0030323 92 64 0,000 0,08524663 0,09122315 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,08524663 0,0911964 ! tRNA processing GO:0008033 73 64 0,000 0,08524663 0,09116966 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,08524663 0,09114294 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,08524663 0,09111624 ! adaptive immune response GO:0002250 70 64 0,000 0,08524663 0,09108955 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,08524663 0,09106288 ! neurotransmitter transport GO:0006836 72 64 0,000 0,08524663 0,09103622 ! regulation of actin cytoskeleton organization GO:0032956 93 64 0,000 0,08524663 0,09100958 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,08524663 0,09098295 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,08652148 0,09231657 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,08652148 0,09228958 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,08652148 0,0922626 ! activation of MAPK activity GO:0000187 74 65 0,000 0,08652148 0,09223564 ! gonad development GO:0008406 71 65 0,000 0,08652148 0,0922087 ! acetyltransferase activity GO:0016407 73 65 0,000 0,08652148 0,09218177 ! protein import into nucleus GO:0006606 73 66 0,000 0,08779462 0,09351089 ! developmental maturation GO:0021700 85 66 0,000 0,08779462 0,09348359 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,08779462 0,09345631 ! tube morphogenesis GO:0035239 84 66 0,000 0,08779462 0,09342905 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,08779462 0,0934018 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,08779462 0,09337457 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,08906606 0,09469921 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,08906606 0,09467161 ! nuclear import GO:0051170 74 67 0,000 0,08906606 0,09464404 ! response to peptide hormone stimulus GO:0043434 79 67 0,000 0,08906606 0,09461648 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,08906606 0,09458893 ! regulation of actin filament-based process GO:0032970 96 67 0,000 0,08906606 0,0945614 ! chloride ion binding GO:0031404 79 67 0,000 0,08906606 0,09453389 ! humoral immune response GO:0006959 75 67 0,000 0,08906606 0,09450639 ! amine binding GO:0043176 77 67 0,000 0,08906606 0,09447891 ! female pregnancy GO:0007565 78 67 0,000 0,08906606 0,09445145 ! extrinsic to membrane GO:0019898 75 67 0,000 0,08906606 0,094424 ! anion channel activity GO:0005253 77 67 0,000 0,08906606 0,09439657 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,08906606 0,09436915 ! amine catabolic process GO:0009310 73 68 0,000 0,09033579 0,09568669 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,09033579 0,09565891 ! cell-substrate junction GO:0030055 78 68 0,000 0,09033579 0,09563115 ! respiratory system development GO:0060541 96 68 0,000 0,09033579 0,09560341 ! mRNA transport GO:0051028 88 69 0,000 0,09160382 0,09691726 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,09160382 0,09688916 ! small GTPase binding GO:0031267 86 69 0,000 0,09160382 0,09686108 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,09160382 0,09683301 ! sarcomere GO:0030017 74 69 0,000 0,09160382 0,09680496 ! exocytosis GO:0006887 76 69 0,000 0,09160382 0,09677693 ! skeletal muscle tissue development GO:0007519 75 69 0,000 0,09160382 0,09674891 GO:0060538|skeletal muscle organ development, ! nucleosome assembly GO:0006334 87 69 0,000 0,09160382 0,0967209 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,09160382 0,09669292 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,09160382 0,09666495 ! amine biosynthetic process GO:0009309 78 70 0,000 0,09287015 0,0979729 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,09287015 0,09794458 ! early endosome GO:0005769 104 70 0,000 0,09287015 0,09791627 ! regulation of lipase activity GO:0060191 78 70 0,000 0,09287015 0,09788798 ! amino acid transport GO:0006865 76 70 0,000 0,09287015 0,0978597 ! chromatin assembly GO:0031497 88 70 0,000 0,09287015 0,09783144 ! calcium channel activity GO:0005262 86 70 0,000 0,09287015 0,0978032 ! axon guidance GO:0007411 87 70 0,000 0,09287015 0,09777498 ! nuclear chromosome part GO:0044454 94 70 0,000 0,09287015 0,09774677 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,09413478 0,09904923 ! mitochondrial outer membrane GO:0005741 81 71 0,000 0,09413478 0,09902067 ! protein localization in nucleus GO:0034504 78 71 0,000 0,09413478 0,09899212 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,09413478 0,09896359 ! pore complex GO:0046930 89 72 0,000 0,09539771 0,10026242 ! response to hypoxia GO:0001666 84 72 0,000 0,09539771 0,10023354 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,09539771 0,10020468 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,09539771 0,10017584 ! acute inflammatory response GO:0002526 91 72 0,000 0,09539771 0,10014701 ! apical junction complex GO:0043296 90 72 0,000 0,09539771 0,1001182 ! phospholipase activity GO:0004620 99 72 0,000 0,09539771 0,1000894 ! regulation of neurological system process GO:0031644 91 72 0,000 0,09539771 0,10006063 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,09665896 0,10135438 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,09665896 0,10132525 ! protein transporter activity GO:0008565 80 73 0,000 0,09665896 0,10129614 ! exopeptidase activity GO:0008238 81 73 0,000 0,09665896 0,10126705 ! digestion GO:0007586 81 73 0,000 0,09665896 0,10123798 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,09665896 0,10120892 ! response to oxygen levels GO:0070482 86 74 0,000 0,09791851 0,10249834 ! potassium channel complex GO:0034705 84 74 0,000 0,09791851 0,10246894 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,09791851 0,10243955 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,09791851 0,10241018 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,09791851 0,10238083 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,09791851 0,1023515 ! blood coagulation GO:0007596 90 74 0,000 0,09791851 0,10232218 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,09791851 0,10229288 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,09791851 0,10226359 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,09791851 0,10223432 ! cell projection part GO:0044463 80 74 0,000 0,09791851 0,10220507 ! regulation of DNA binding GO:0051101 94 75 0,000 0,09917637 0,10348839 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,09917637 0,10345879 ! regulation of blood pressure GO:0008217 82 75 0,000 0,09917637 0,10342922 ! transcription initiation GO:0006352 84 75 0,000 0,09917637 0,10339966 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,09917637 0,10337012 ! defense response to bacterium GO:0042742 81 76 0,000 0,10043255 0,10464951 ! cell leading edge GO:0031252 97 76 0,000 0,10043255 0,10461963 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,10043255 0,10458976 ! protein-DNA complex GO:0032993 93 76 0,000 0,10043255 0,10455991 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,10043255 0,10453008 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,10043255 0,10450027 ! cytosolic ribosome GO:0022626 82 76 0,000 0,10043255 0,10447047 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,10043255 0,10444069 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,10168704 0,10571511 ! nucleosome organization GO:0034728 96 77 0,000 0,10168704 0,10568499 ! alcohol catabolic process GO:0046164 84 77 0,000 0,10168704 0,10565489 ! vacuolar membrane GO:0005774 86 77 0,000 0,10168704 0,10562481 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,10168704 0,10559474 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,10168704 0,10556469 ! establishment of RNA localization GO:0051236 97 77 0,000 0,10168704 0,10553466 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! myofibril GO:0030016 82 77 0,000 0,10168704 0,10550464 ! protein oligomerization GO:0051259 93 77 0,000 0,10168704 0,10547464 ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,10293985 0,10674377 ! endonuclease activity GO:0004519 111 78 0,000 0,10293985 0,10671343 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,10293985 0,10668312 ! inorganic anion transport GO:0015698 87 78 0,000 0,10293985 0,10665282 ! regulation of protein transport GO:0051223 85 78 0,000 0,10293985 0,10662254 ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,10293985 0,10659227 ! carboxylesterase activity GO:0004091 93 78 0,000 0,10293985 0,10656203 ! protein ubiquitination GO:0016567 95 78 0,000 0,10293985 0,10653179 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,10293985 0,10650158 ! contractile fiber part GO:0044449 83 78 0,000 0,10293985 0,10647139 ! RNA localization GO:0006403 99 79 0,000 0,10419098 0,10773489 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,10419098 0,10770436 ! vitamin metabolic process GO:0006766 86 79 0,000 0,10419098 0,10767385 ! T cell activation GO:0042110 120 79 0,000 0,10419098 0,10764336 ! cellular response to hormone stimulus GO:0032870 94 79 0,000 0,10419098 0,10761288 ! phosphoinositide binding GO:0035091 99 79 0,000 0,10419098 0,10758242 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,10544043 0,10884174 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,10544043 0,10881095 ! rhythmic process GO:0048511 90 80 0,000 0,10544043 0,10878018 ! regulation of catabolic process GO:0009894 87 80 0,000 0,10544043 0,10874942 ! SH3 domain binding GO:0017124 95 80 0,000 0,10544043 0,10871868 ! hemostasis GO:0007599 96 80 0,000 0,10544043 0,10868796 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,10544043 0,10865726 ! rRNA processing GO:0006364 84 80 0,000 0,10544043 0,10862657 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,10668821 0,10988102 ! vacuolar part GO:0044437 91 81 0,000 0,10668821 0,10985001 ! ossification GO:0001503 111 82 0,000 0,10793431 0,11110168 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,10793431 0,11107034 ! forebrain development GO:0030900 93 82 0,000 0,10793431 0,11103902 ! external side of plasma membrane GO:0009897 105 82 0,000 0,10793431 0,11100772 ! cellular respiration GO:0045333 85 82 0,000 0,10793431 0,11097643 ! heparin binding GO:0008201 108 82 0,000 0,10793431 0,11094516 ! nuclear speck GO:0016607 99 83 0,000 0,10917874 0,11219269 ! rRNA metabolic process GO:0016072 88 83 0,000 0,10917874 0,1121611 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,10917874 0,11212952 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,10917874 0,11209796 ! regulation of T cell activation GO:0050863 104 83 0,000 0,10917874 0,11206642 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,10917874 0,1120349 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,10917874 0,11200339 ! contractile fiber GO:0043292 88 83 0,000 0,10917874 0,1119719 ! bone development GO:0060348 112 83 0,000 0,10917874 0,11194043 ! regulation of membrane potential GO:0042391 98 83 0,000 0,10917874 0,11190898 ! cilium GO:0005929 88 83 0,000 0,10917874 0,11187754 ! regulation of defense response GO:0031347 98 84 0,000 0,1104215 0,11311925 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,1104215 0,11308749 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,1104215 0,11305575 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,1116626 0,11429438 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,1116626 0,11426232 ! monooxygenase activity GO:0004497 92 85 0,000 0,1116626 0,11423028 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,1116626 0,11419825 ! protein binding, bridging GO:0030674 104 85 0,000 0,1116626 0,11416625 ! negative regulation of transport GO:0051051 98 86 0,000 0,11290203 0,11540112 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,11290203 0,1153688 ! lipase activity GO:0016298 114 86 0,000 0,11290203 0,11533649 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,11290203 0,1153042 ! adherens junction GO:0005912 100 86 0,000 0,11290203 0,11527193 ! leukocyte differentiation GO:0002521 118 87 0,000 0,1141398 0,11650307 ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,1141398 0,11647048 ! organelle outer membrane GO:0031968 102 88 0,000 0,1153759 0,11769891 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,1153759 0,117666 ! growth factor binding GO:0019838 102 88 0,000 0,1153759 0,11763312 ! protein processing GO:0016485 100 88 0,000 0,1153759 0,11760025 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,11661035 0,11882529 ! gland development GO:0048732 108 89 0,000 0,11661035 0,11879211 ! ATP metabolic process GO:0046034 100 90 0,000 0,11784314 0,12001445 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,11784314 0,11998096 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,11784314 0,11994748 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,11784314 0,11991402 ! sterol metabolic process GO:0016125 102 90 0,000 0,11784314 0,11988058 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,11784314 0,11984716 ! anion binding GO:0043168 104 90 0,000 0,11784314 0,11981376 ! amine transport GO:0015837 97 90 0,000 0,11784314 0,11978038 ! response to virus GO:0009615 109 90 0,000 0,11784314 0,11974701 ! outer membrane GO:0019867 104 90 0,000 0,11784314 0,11971367 ! extracellular matrix part GO:0044420 111 90 0,000 0,11784314 0,11968034 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,11907428 0,12089701 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,11907428 0,12086337 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,11907428 0,12082975 ! sulfur metabolic process GO:0006790 98 91 0,000 0,11907428 0,12079615 ! sex differentiation GO:0007548 103 91 0,000 0,11907428 0,12076257 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,11907428 0,12072901 ! hormone metabolic process GO:0042445 107 91 0,000 0,11907428 0,12069546 ! regulation of protein localization GO:0032880 99 91 0,000 0,11907428 0,12066193 ! detection of stimulus GO:0051606 100 91 0,000 0,11907428 0,12062843 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,12030376 0,12184012 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,12030376 0,12180631 ! regulation of cellular component biogenesis GO:0044087 115 92 0,000 0,12030376 0,12177251 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,12030376 0,12173873 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,12030376 0,12170497 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,12030376 0,12167123 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,12030376 0,12163751 ! extracellular structure organization GO:0043062 119 92 0,000 0,12030376 0,1216038 ! protein import GO:0017038 102 93 0,000 0,1215316 0,12281088 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,1215316 0,12277687 ! response to nutrient levels GO:0031667 105 93 0,000 0,1215316 0,12274288 ! Ras protein signal transduction GO:0007265 118 93 0,000 0,1215316 0,1227089 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,1215316 0,12267495 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,12275778 0,12387839 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,12275778 0,12384414 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,12275778 0,1238099 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,12275778 0,12377568 ! neurotransmitter binding GO:0042165 105 94 0,000 0,12275778 0,12374147 ! DNA packaging GO:0006323 113 94 0,000 0,12275778 0,12370729 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,12398232 0,1249068 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,12398232 0,12487231 ! protein localization in organelle GO:0033365 104 95 0,000 0,12398232 0,12483785 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,12398232 0,1248034 ! apical plasma membrane GO:0016324 105 95 0,000 0,12398232 0,12476897 ! translational elongation GO:0006414 104 96 0,000 0,12520522 0,12596488 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,12520522 0,12593015 ! in utero embryonic development GO:0001701 110 96 0,000 0,12520522 0,12589544 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,12520522 0,12586075 ! receptor complex GO:0043235 131 96 0,000 0,12520522 0,12582607 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,12520522 0,12579142 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,12520522 0,12575679 ! electron transport chain GO:0022900 104 97 0,000 0,12642648 0,12694847 ! microtubule associated complex GO:0005875 135 97 0,000 0,12642648 0,12691354 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,12642648 0,12687862 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,12642648 0,12684373 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,12642648 0,12680885 ! carboxylic acid binding GO:0031406 108 97 0,000 0,12642648 0,12677399 ! protein maturation GO:0051604 109 97 0,000 0,12642648 0,12673916 ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,12764609 0,12792663 ! cell fate commitment GO:0045165 118 98 0,000 0,12764609 0,1278915 ! hormone activity GO:0005179 113 99 0,000 0,12886407 0,12907637 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,12886407 0,12904094 ! unfolded protein binding GO:0051082 118 100 0,000 0,13008042 0,1302232 ! nuclear chromosome GO:0000228 127 100 0,000 0,13008042 0,13018748 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,13008042 0,13015177 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,13008042 0,13011608 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,13008042 0,13008042