pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/55775-6-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! embryonic cleavage GO:0040016 6 5 3,000 5,965E-12 1,435E-08 ! DNA topological change GO:0006265 12 8 3,000 8,332E-11 1,002E-07 ! DNA unwinding during replication GO:0006268 27 17 3,000 2,813E-09 2,256E-06 ! DNA duplex unwinding GO:0032508 31 20 3,000 5,714E-09 3,437E-06 GO:0032392|DNA geometric change, ! DNA-dependent DNA replication GO:0006261 74 49 3,000 2,443E-07 1,176E-04 ! response to drug GO:0042493 143 82 3,000 1,966E-06 7,886E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 2,712E-06 9,32E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 3,544E-06 1,066E-03 ! interphase GO:0051325 213 98 3,000 4,012E-06 1,072E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 1,162E-05 2,795E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 1,162E-05 2,541E-03 GO:0032862|activation of Rho GTPase activity, ! protein refolding GO:0042026 15 6 1,000 1,742E-05 3,492E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,762E-05 3,261E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,004E-05 3,445E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 2,437E-05 3,908E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 2,437E-05 3,664E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,437E-05 3,449E-03 ! spindle checkpoint GO:0031577 15 7 1,000 2,437E-05 3,257E-03 ! response to UV GO:0009411 104 53 2,000 2,705E-05 3,425E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,247E-05 3,906E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 3,247E-05 3,72E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 3,247E-05 3,551E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! mast cell activation GO:0045576 14 8 1,000 3,247E-05 3,396E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 3,247E-05 3,255E-03 ! establishment of chromosome localization GO:0051303 12 8 1,000 3,247E-05 3,124E-03 GO:0050000|chromosome localization, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 3,368E-05 3,117E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 4,171E-05 3,717E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 5,211E-05 4,477E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 5,211E-05 4,323E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 5,211E-05 4,179E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 5,211E-05 4,044E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 5,211E-05 3,918E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 6,364E-05 4,64E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 6,364E-05 4,504E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 7,632E-05 5,246E-03 ! cartilage condensation GO:0001502 20 12 1,000 7,632E-05 5,1E-03 ! regulation of exit from mitosis GO:0007096 17 12 1,000 7,632E-05 4,963E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 9,013E-05 5,707E-03 ! response to metal ion GO:0010038 140 80 2,000 9,297E-05 5,735E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 1,051E-04 6,321E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,051E-04 6,166E-03 ! response to unfolded protein GO:0006986 131 85 2,000 1,113E-04 6,378E-03 ! response to inorganic substance GO:0010035 153 86 2,000 1,153E-04 6,45E-03 ! response to protein stimulus GO:0051789 149 91 2,000 1,363E-04 7,455E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,384E-04 7,399E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,384E-04 7,238E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,567E-04 8,023E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,567E-04 7,856E-03 ! cell cycle arrest GO:0007050 213 100 2,000 1,803E-04 8,851E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,968E-04 9,469E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptide cross-linking GO:0018149 37 19 1,000 1,968E-04 9,283E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,185E-04 0,01010967 ! negative regulation of translation GO:0017148 29 20 1,000 2,185E-04 9,919E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 2,413E-04 0,01075263 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,653E-04 0,01160488 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,903E-04 0,01247458 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,903E-04 0,01225573 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,165E-04 0,01313036 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 3,165E-04 0,01290781 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,165E-04 0,01269268 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,438E-04 0,01356093 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,722E-04 0,01444415 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,722E-04 0,01421487 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,017E-04 0,01510183 ! fat cell differentiation GO:0045444 50 27 1,000 4,017E-04 0,0148695 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,017E-04 0,0146442 ! negative regulation of protein modification process GO:0031400 60 28 1,000 4,323E-04 0,01552465 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,323E-04 0,01529635 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,64E-04 0,01618021 ! acute-phase response GO:0006953 49 30 1,000 4,968E-04 0,01707657 ! regulation of B cell activation GO:0050864 50 30 1,000 4,968E-04 0,01683606 ! myeloid leukocyte activation GO:0002274 49 31 1,000 5,307E-04 0,01773505 ! response to mechanical stimulus GO:0009612 57 32 1,000 5,657E-04 0,01864546 ! xenobiotic metabolic process GO:0006805 51 34 1,000 6,39E-04 0,02077544 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,772E-04 0,02172587 ! RNA export from nucleus GO:0006405 56 37 1,000 7,57E-04 0,02396553 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 7,985E-04 0,02495132 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to xenobiotic stimulus GO:0009410 57 39 1,000 8,411E-04 0,02594509 ! cytokinesis GO:0000910 72 40 1,000 8,848E-04 0,02694645 ! JAK-STAT cascade GO:0007259 71 44 1,000 1,07E-03 0,03218441 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,119E-03 0,03324277 ! response to insulin stimulus GO:0032868 95 46 1,000 1,169E-03 0,03430648 ! response to calcium ion GO:0051592 81 47 1,000 1,22E-03 0,03537528 ! mitochondrial transport GO:0006839 82 48 1,000 1,273E-03 0,03644893 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,273E-03 0,03602012 ! detection of abiotic stimulus GO:0009582 74 49 1,000 1,326E-03 0,03709083 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 1,435E-03 0,03969667 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 1,435E-03 0,03924557 ! cartilage development GO:0051216 90 52 1,000 1,492E-03 0,04032918 ! nuclear export GO:0051168 97 55 1,000 1,667E-03 0,0445716 ! positive regulation of organelle organization GO:0010638 100 56 1,000 1,728E-03 0,04568319 ! skeletal system morphogenesis GO:0048705 105 59 1,000 1,916E-03 0,05010117 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 1,916E-03 0,04956245 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 1,916E-03 0,04903519 ! establishment of organelle localization GO:0051656 109 59 1,000 1,916E-03 0,04851903 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 2,046E-03 0,05128276 ! regulation of mitosis GO:0007088 105 63 1,000 2,181E-03 0,05409137 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 2,181E-03 0,05353942 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 2,462E-03 0,05983607 ! negative regulation of cell growth GO:0030308 132 67 1,000 2,462E-03 0,05923771 ! chromosome segregation GO:0007059 113 67 1,000 2,462E-03 0,05865119 ! negative regulation of kinase activity GO:0033673 131 68 1,000 2,535E-03 0,05979517 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 2,535E-03 0,05921463 ! cell cycle checkpoint GO:0000075 137 69 1,000 2,609E-03 0,06035459 ! negative regulation of cell size GO:0045792 134 69 1,000 2,609E-03 0,05977978 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 2,609E-03 0,05921582 ! acute inflammatory response GO:0002526 113 72 1,000 2,837E-03 0,06378257 ! regulation of caspase activity GO:0043281 122 72 1,000 2,837E-03 0,06319199 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 2,837E-03 0,06261225 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 2,837E-03 0,06204305 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 2,837E-03 0,0614841 ! negative regulation of transferase activity GO:0051348 140 72 1,000 2,837E-03 0,06093513 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 2,993E-03 0,06373491 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 2,993E-03 0,06317583 ! organelle localization GO:0051640 136 74 1,000 2,993E-03 0,06262648 ! cell-matrix adhesion GO:0007160 163 75 1,000 3,073E-03 0,06374402 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 3,236E-03 0,06654713 ! regulation of actin filament-based process GO:0032970 152 77 1,000 3,236E-03 0,06598317 ! positive regulation of ligase activity GO:0051351 124 77 1,000 3,236E-03 0,06542869 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 3,236E-03 0,06488345 ! regulation of peptidase activity GO:0052547 134 79 1,000 3,403E-03 0,06766338 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 3,403E-03 0,06710876 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 3,403E-03 0,06656316 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 3,574E-03 0,06933895 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 3,574E-03 0,06878424 ! negative regulation of growth GO:0045926 155 84 1,000 3,837E-03 0,07326909 ! regulation of ligase activity GO:0051340 142 84 1,000 3,837E-03 0,07269216 ! positive regulation of cell activation GO:0050867 145 85 1,000 3,927E-03 0,07381176 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 4,018E-03 0,07493218 ! positive regulation of protein modification process GO:0031401 136 88 1,000 4,202E-03 0,07776893 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 4,296E-03 0,07889552 ! regulation of cell adhesion GO:0030155 212 89 1,000 4,296E-03 0,07829783 ! regulation of cell cycle process GO:0010564 149 90 1,000 4,39E-03 0,07942099 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 4,68E-03 0,08402933 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 4,878E-03 0,08693401 ! detection of stimulus GO:0051606 151 96 1,000 4,978E-03 0,08807072 ! Golgi vesicle transport GO:0048193 207 99 1,000 5,285E-03 0,09281692 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,467E-03 0,095316 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,467E-03 0,09463027 ! positive regulation of helicase activity GO:0051096 11 5 0,000 5,467E-03 0,09395434 ! neuron fate determination GO:0048664 7 5 0,000 5,467E-03 0,093288 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,467E-03 0,09263104 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 5,467E-03 0,09198327 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,467E-03 0,0913445 ! polyol transport GO:0015791 12 5 0,000 5,467E-03 0,09071454 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 5,467E-03 0,09009321 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,467E-03 0,08948033 ! response to superoxide GO:0000303 10 5 0,000 5,467E-03 0,08887573 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,467E-03 0,08827925 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 5,467E-03 0,08769072 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 5,467E-03 0,08710999 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,467E-03 0,0865369 ! female meiosis GO:0007143 7 5 0,000 5,467E-03 0,0859713 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,467E-03 0,08541304 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,467E-03 0,08486199 ! cobalt ion transport GO:0006824 11 5 0,000 5,467E-03 0,084318 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 5,467E-03 0,08378094 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 5,467E-03 0,08325068 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 5,467E-03 0,0827271 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,467E-03 0,08221005 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,467E-03 0,08169943 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 5,467E-03 0,08119511 ! embryonic camera-type eye development GO:0031076 10 5 0,000 5,467E-03 0,08069698 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,467E-03 0,08020493 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 5,467E-03 0,07971884 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 5,467E-03 0,0792386 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,467E-03 0,07876412 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,467E-03 0,07829529 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,467E-03 0,077832 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 5,467E-03 0,07737417 ! negative chemotaxis GO:0050919 14 5 0,000 5,467E-03 0,07692169 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,467E-03 0,07647447 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,467E-03 0,07603242 ! sensory perception of bitter taste GO:0050913 7 5 0,000 5,467E-03 0,07559545 ! behavioral response to pain GO:0048266 9 5 0,000 5,467E-03 0,07516348 ! clathrin coat assembly GO:0048268 14 5 0,000 5,467E-03 0,07473641 ! Notch receptor processing GO:0007220 8 5 0,000 5,467E-03 0,07431417 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,467E-03 0,07389668 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,467E-03 0,07348384 ! micturition GO:0060073 9 5 0,000 5,467E-03 0,0730756 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,467E-03 0,07267187 ! copulation GO:0007620 9 5 0,000 5,467E-03 0,07227257 ! glial cell fate commitment GO:0021781 13 5 0,000 5,467E-03 0,07187764 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,467E-03 0,071487 ! spermidine metabolic process GO:0008216 7 5 0,000 5,467E-03 0,07110058 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,467E-03 0,07071832 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,467E-03 0,07034015 ! apoptotic cell clearance GO:0043277 20 5 0,000 5,467E-03 0,069966 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,467E-03 0,06959581 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,467E-03 0,06922952 ! grooming behavior GO:0007625 6 5 0,000 5,467E-03 0,06886706 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,467E-03 0,06850838 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 5,467E-03 0,06815341 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,467E-03 0,0678021 ! response to protozoan GO:0001562 10 5 0,000 5,467E-03 0,0674544 ! positive regulation of glycolysis GO:0045821 14 5 0,000 5,467E-03 0,06711025 ! lymph vessel development GO:0001945 10 5 0,000 5,467E-03 0,06676958 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 5,467E-03 0,06643236 ! endochondral ossification GO:0001958 16 5 0,000 5,467E-03 0,06609853 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,467E-03 0,06576804 ! parathyroid gland development GO:0060017 13 5 0,000 5,467E-03 0,06544084 ! anagen GO:0042640 6 5 0,000 5,467E-03 0,06511687 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,467E-03 0,0647961 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,467E-03 0,06447847 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 5,467E-03 0,06416394 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 5,467E-03 0,06385247 ! dorsal spinal cord development GO:0021516 7 5 0,000 5,467E-03 0,063544 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 5,467E-03 0,0632385 ! sphingoid catabolic process GO:0046521 6 5 0,000 5,467E-03 0,06293592 ! skeletal myofibril assembly GO:0014866 10 5 0,000 5,467E-03 0,06263623 ! smooth muscle tissue development GO:0048745 28 5 0,000 5,467E-03 0,06233938 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,467E-03 0,06204532 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,467E-03 0,06175403 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,467E-03 0,06146546 ! cardiac muscle fiber development GO:0048739 10 5 0,000 5,467E-03 0,06117957 ! transepithelial chloride transport GO:0030321 9 5 0,000 5,467E-03 0,06089633 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,467E-03 0,06061571 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 5,467E-03 0,06033765 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 5,467E-03 0,06006214 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,467E-03 0,05978913 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,467E-03 0,05951859 ! histidine catabolic process GO:0006548 6 5 0,000 5,467E-03 0,05925049 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 5,467E-03 0,05898479 ! microvillus organization GO:0032528 7 5 0,000 5,467E-03 0,05872147 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 5,467E-03 0,05846048 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,467E-03 0,05820181 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,467E-03 0,05794541 ! tryptophan metabolic process GO:0006568 9 5 0,000 5,467E-03 0,05769126 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 5,467E-03 0,05743934 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,467E-03 0,0571896 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 5,467E-03 0,05694203 ! polyol catabolic process GO:0046174 7 5 0,000 5,467E-03 0,05669659 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,467E-03 0,05645325 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,467E-03 0,056212 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,467E-03 0,0559728 ! muscle cell migration GO:0014812 8 5 0,000 5,467E-03 0,05573563 ! mitochondrial fission GO:0000266 8 5 0,000 5,467E-03 0,05550046 ! sister chromatid cohesion GO:0007062 12 5 0,000 5,467E-03 0,05526726 ! mRNA transcription GO:0009299 9 5 0,000 5,467E-03 0,05503602 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 5,467E-03 0,0548067 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 5,467E-03 0,05457929 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 5,467E-03 0,05435375 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,467E-03 0,05413007 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,467E-03 0,05390823 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,467E-03 0,0536882 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,467E-03 0,05346995 ! response to food GO:0032094 6 5 0,000 5,467E-03 0,05325347 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,467E-03 0,05303874 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,467E-03 0,05282574 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 5,467E-03 0,05261443 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,467E-03 0,05240481 ! paraxial mesoderm development GO:0048339 14 5 0,000 5,467E-03 0,05219686 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 5,467E-03 0,05199055 ! forebrain neuron development GO:0021884 13 5 0,000 5,467E-03 0,05178586 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,467E-03 0,05158278 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 5,467E-03 0,05138128 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,467E-03 0,05118135 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,467E-03 0,05098298 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,467E-03 0,05078613 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 5,467E-03 0,0505908 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,467E-03 0,05039697 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 5,467E-03 0,05020461 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 5,467E-03 0,05001372 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,467E-03 0,04982427 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 5,467E-03 0,04963626 ! basic amino acid transport GO:0015802 11 5 0,000 5,467E-03 0,04944965 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,467E-03 0,04926445 ! early endosome to late endosome transport GO:0045022 12 5 0,000 5,467E-03 0,04908063 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,467E-03 0,04889817 ! depyrimidination GO:0045008 10 5 0,000 5,467E-03 0,04871707 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,467E-03 0,0485373 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,467E-03 0,04835885 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,467E-03 0,04818172 ! zinc ion homeostasis GO:0055069 8 5 0,000 5,467E-03 0,04800587 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 5,467E-03 0,0478313 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 5,467E-03 0,047658 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,467E-03 0,04748595 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,467E-03 0,04731514 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,467E-03 0,04714555 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 5,467E-03 0,04697717 ! peptidyl-arginine modification GO:0018195 9 5 0,000 5,467E-03 0,04680999 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,467E-03 0,046644 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,467E-03 0,04647918 ! response to arsenic GO:0046685 10 5 0,000 5,467E-03 0,04631552 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,467E-03 0,04615301 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,467E-03 0,04599164 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 5,467E-03 0,04583139 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 5,467E-03 0,04567225 ! response to cadmium ion GO:0046686 7 5 0,000 5,467E-03 0,04551422 ! bile acid biosynthetic process GO:0006699 6 5 0,000 5,467E-03 0,04535727 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 5,467E-03 0,0452014 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,467E-03 0,0450466 ! decidualization GO:0046697 11 5 0,000 5,467E-03 0,04489286 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 5,467E-03 0,04474016 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 5,467E-03 0,0445885 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,467E-03 0,04443787 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,467E-03 0,04428824 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 5,467E-03 0,04413962 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,467E-03 0,043992 ! neural tube patterning GO:0021532 7 5 0,000 5,467E-03 0,04384536 ! peroxisome fission GO:0016559 5 5 0,000 5,467E-03 0,0436997 ! histone demethylation GO:0016577 10 5 0,000 5,467E-03 0,04355499 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 5,467E-03 0,04341125 ! mitotic recombination GO:0006312 9 5 0,000 5,467E-03 0,04326845 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,467E-03 0,04312658 ! metaphase plate congression GO:0051310 7 5 0,000 5,467E-03 0,04298565 ! regulation of sterol transport GO:0032371 7 5 0,000 5,467E-03 0,04284563 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,467E-03 0,04270652 ! enteric nervous system development GO:0048484 8 5 0,000 5,467E-03 0,04256831 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 5,467E-03 0,04243099 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 5,467E-03 0,04229456 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 5,467E-03 0,042159 ! muscle cell proliferation GO:0033002 11 5 0,000 5,467E-03 0,04202431 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,467E-03 0,04189047 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 5,467E-03 0,04175749 ! plasminogen activation GO:0031639 5 5 0,000 5,467E-03 0,04162534 ! B cell homeostasis GO:0001782 13 5 0,000 5,467E-03 0,04149403 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,467E-03 0,04136355 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,467E-03 0,04123388 ! metaphase GO:0051323 8 5 0,000 5,467E-03 0,04110503 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 5,467E-03 0,04097697 ! cellular response to nutrient GO:0031670 8 5 0,000 5,467E-03 0,04084971 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,467E-03 0,04072325 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,467E-03 0,04059756 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,467E-03 0,04047264 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 5,467E-03 0,04034849 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 5,467E-03 0,0402251 ! response to redox state GO:0051775 5 5 0,000 5,467E-03 0,04010246 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 5,467E-03 0,03998057 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 5,467E-03 0,03985942 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,467E-03 0,039739 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,467E-03 0,0396193 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,467E-03 0,03950032 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 5,467E-03 0,03938206 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,467E-03 0,0392645 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 5,467E-03 0,03914764 ! striatum development GO:0021756 9 5 0,000 5,467E-03 0,03903148 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 5,467E-03 0,038916 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,467E-03 0,0388012 ! glial cell migration GO:0008347 11 5 0,000 5,467E-03 0,03868708 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,467E-03 0,03857363 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 5,467E-03 0,03846084 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,467E-03 0,03834871 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,467E-03 0,03823723 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,467E-03 0,0381264 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,467E-03 0,03801621 ! neuroprotection GO:0043526 6 5 0,000 5,467E-03 0,03790665 ! neural plate development GO:0001840 8 5 0,000 5,467E-03 0,03779772 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,467E-03 0,03768942 ! regulation of sensory perception GO:0051931 7 5 0,000 5,467E-03 0,03758174 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,467E-03 0,03747467 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,467E-03 0,03736821 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 5,467E-03 0,03726235 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 5,467E-03 0,03715709 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,467E-03 0,03705242 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,467E-03 0,03694834 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,467E-03 0,03684484 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,467E-03 0,03674192 ! spindle assembly GO:0051225 6 5 0,000 5,467E-03 0,03663958 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,467E-03 0,0365378 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,467E-03 0,03643659 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,467E-03 0,03633593 ! drug metabolic process GO:0017144 6 5 0,000 5,467E-03 0,03623584 ! stem cell division GO:0017145 11 5 0,000 5,467E-03 0,03613629 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,467E-03 0,03603728 ! organ regeneration GO:0031100 7 5 0,000 5,467E-03 0,03593882 ! carnitine metabolic process GO:0009437 7 5 0,000 5,467E-03 0,03584089 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 5,467E-03 0,0357435 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,467E-03 0,03564663 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,557E-03 0,0426377 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,557E-03 0,04252277 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 6,557E-03 0,04240847 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,557E-03 0,04229477 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,557E-03 0,04218168 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 6,557E-03 0,0420692 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 6,557E-03 0,04195731 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,557E-03 0,04184602 ! sleep GO:0030431 13 6 0,000 6,557E-03 0,04173532 ! response to oxygen radical GO:0000305 11 6 0,000 6,557E-03 0,0416252 ! positive regulation of axon extension GO:0045773 11 6 0,000 6,557E-03 0,04151566 ! myoblast cell fate commitment GO:0048625 16 6 0,000 6,557E-03 0,04140669 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 6,557E-03 0,0412983 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 6,557E-03 0,04119047 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,557E-03 0,0410832 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,557E-03 0,04097649 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 6,557E-03 0,04087033 ! forebrain regionalization GO:0021871 8 6 0,000 6,557E-03 0,04076473 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,557E-03 0,04065966 ! male meiosis GO:0007140 7 6 0,000 6,557E-03 0,04055514 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,557E-03 0,04045115 ! response to zinc ion GO:0010043 9 6 0,000 6,557E-03 0,0403477 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,557E-03 0,04024477 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 6,557E-03 0,04014236 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 6,557E-03 0,04004048 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,557E-03 0,03993911 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,557E-03 0,03983826 ! malate metabolic process GO:0006108 11 6 0,000 6,557E-03 0,03973791 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 6,557E-03 0,03963806 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 6,557E-03 0,03953872 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,557E-03 0,03943987 ! opsonization GO:0008228 8 6 0,000 6,557E-03 0,03934152 ! mating behavior GO:0007617 7 6 0,000 6,557E-03 0,03924365 ! neuron remodeling GO:0016322 15 6 0,000 6,557E-03 0,03914628 ! erythrocyte maturation GO:0043249 7 6 0,000 6,557E-03 0,03904938 ! embryonic hemopoiesis GO:0035162 14 6 0,000 6,557E-03 0,03895296 ! equilibrioception GO:0050957 14 6 0,000 6,557E-03 0,03885702 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,557E-03 0,03876155 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 6,557E-03 0,03866654 ! photoreceptor cell development GO:0042461 10 6 0,000 6,557E-03 0,038572 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,557E-03 0,03847792 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,557E-03 0,0383843 ! response to interferon-gamma GO:0034341 15 6 0,000 6,557E-03 0,03829114 ! toxin metabolic process GO:0009404 11 6 0,000 6,557E-03 0,03819842 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,557E-03 0,03810616 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,557E-03 0,03801434 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 6,557E-03 0,03792295 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 6,557E-03 0,03783201 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 6,557E-03 0,03774151 ! cGMP-mediated signaling GO:0019934 13 6 0,000 6,557E-03 0,03765143 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,557E-03 0,03756178 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 6,557E-03 0,03747256 ! thymic T cell selection GO:0045061 12 6 0,000 6,557E-03 0,03738377 ! protein lipoylation GO:0009249 10 6 0,000 6,557E-03 0,03729539 ! cysteine metabolic process GO:0006534 10 6 0,000 6,557E-03 0,03720743 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,557E-03 0,03711988 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,557E-03 0,03703274 ! glutamate catabolic process GO:0006538 10 6 0,000 6,557E-03 0,03694602 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 6,557E-03 0,03685969 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,557E-03 0,03677377 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 6,557E-03 0,03668825 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 6,557E-03 0,03660313 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,557E-03 0,0365184 ! hyperosmotic response GO:0006972 9 6 0,000 6,557E-03 0,03643406 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 6,557E-03 0,03635011 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 6,557E-03 0,03626655 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,557E-03 0,03618337 ! urea metabolic process GO:0019627 7 6 0,000 6,557E-03 0,03610057 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,557E-03 0,03601815 ! neutrophil activation GO:0042119 8 6 0,000 6,557E-03 0,0359361 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,557E-03 0,03585443 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 6,557E-03 0,03577313 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,557E-03 0,03569219 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,557E-03 0,03561162 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,557E-03 0,03553142 ! neuron apoptosis GO:0051402 9 6 0,000 6,557E-03 0,03545157 ! nucleoside salvage GO:0043174 9 6 0,000 6,557E-03 0,03537208 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 6,557E-03 0,03529295 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,557E-03 0,03521417 ! T cell mediated immunity GO:0002456 16 6 0,000 6,557E-03 0,03513574 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,557E-03 0,03505766 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 6,557E-03 0,03497993 ! carnitine transport GO:0015879 10 6 0,000 6,557E-03 0,03490254 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 6,557E-03 0,03482549 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,557E-03 0,03474879 ! positive regulation of exocytosis GO:0045921 8 6 0,000 6,557E-03 0,03467242 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 6,557E-03 0,03459638 ! 5S class rRNA transcription GO:0042791 11 6 0,000 6,557E-03 0,03452068 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,557E-03 0,0344453 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 6,557E-03 0,03437026 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 6,557E-03 0,03429554 ! sodium ion homeostasis GO:0055078 11 6 0,000 6,557E-03 0,03422115 ! establishment of spindle localization GO:0051293 12 6 0,000 6,557E-03 0,03414708 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,557E-03 0,03407332 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,557E-03 0,03399989 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 6,557E-03 0,03392677 ! neural nucleus development GO:0048857 14 6 0,000 6,557E-03 0,03385397 ! response to UV-C GO:0010225 11 6 0,000 6,557E-03 0,03378148 ! astrocyte development GO:0014002 15 6 0,000 6,557E-03 0,03370929 ! protein targeting to lysosome GO:0006622 10 6 0,000 6,557E-03 0,03363742 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,557E-03 0,03356585 ! interaction with symbiont GO:0051702 13 6 0,000 6,557E-03 0,03349458 ! regulation of dendrite development GO:0050773 16 6 0,000 6,557E-03 0,03342362 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,557E-03 0,03335296 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 6,557E-03 0,03328259 ! response to copper ion GO:0046688 10 6 0,000 6,557E-03 0,03321252 ! response to exogenous dsRNA GO:0043330 10 6 0,000 6,557E-03 0,03314275 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 6,557E-03 0,03307327 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,557E-03 0,03300408 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,557E-03 0,03293518 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,557E-03 0,03286656 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 6,557E-03 0,03279823 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,557E-03 0,03273018 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,557E-03 0,03266242 ! hair follicle maturation GO:0048820 7 6 0,000 6,557E-03 0,03259494 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,557E-03 0,03252773 ! Schwann cell development GO:0014044 15 6 0,000 6,557E-03 0,0324608 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,557E-03 0,03239415 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,557E-03 0,03232776 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 6,557E-03 0,03226165 ! subpallium development GO:0021544 10 6 0,000 6,557E-03 0,03219581 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 6,557E-03 0,03213024 ! histone ubiquitination GO:0016574 8 6 0,000 6,557E-03 0,03206494 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 6,557E-03 0,0319999 ! maintenance of organ identity GO:0048496 9 6 0,000 6,557E-03 0,03193512 ! G2 phase GO:0051319 16 6 0,000 6,557E-03 0,0318706 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 6,557E-03 0,03180635 ! establishment of planar polarity GO:0001736 7 6 0,000 6,557E-03 0,03174235 ! regulation of mast cell activation GO:0033003 12 6 0,000 6,557E-03 0,03167861 ! membrane to membrane docking GO:0022614 14 6 0,000 6,557E-03 0,03161513 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,557E-03 0,0315519 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 6,557E-03 0,03148892 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,557E-03 0,03142619 ! receptor internalization GO:0031623 10 6 0,000 6,557E-03 0,03136372 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 6,557E-03 0,03130149 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 6,557E-03 0,0312395 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,557E-03 0,03117777 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 6,557E-03 0,03111627 ! protein deubiquitination GO:0016579 14 6 0,000 6,557E-03 0,03105502 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 6,557E-03 0,03099401 ! protein destabilization GO:0031648 9 6 0,000 6,557E-03 0,03093323 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,557E-03 0,0308727 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 6,557E-03 0,0308124 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,557E-03 0,03075234 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 6,557E-03 0,03069251 ! progesterone metabolic process GO:0042448 10 6 0,000 6,557E-03 0,03063291 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 6,557E-03 0,03057354 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 6,557E-03 0,03051441 ! negative regulation of axon extension GO:0030517 21 6 0,000 6,557E-03 0,0304555 ! removal of superoxide radicals GO:0019430 11 6 0,000 6,557E-03 0,03039682 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,557E-03 0,03033836 ! determination of adult lifespan GO:0008340 15 6 0,000 6,557E-03 0,03028013 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 6,557E-03 0,03022212 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 6,557E-03 0,03016434 ! cerebellar cortex formation GO:0021697 8 6 0,000 6,557E-03 0,03010677 ! catecholamine transport GO:0051937 9 6 0,000 6,557E-03 0,03004943 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 6,557E-03 0,0299923 ! sensory cilium assembly GO:0035058 10 6 0,000 6,557E-03 0,02993539 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,557E-03 0,02987869 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 6,557E-03 0,02982221 ! maternal placenta development GO:0001893 12 6 0,000 6,557E-03 0,02976594 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 6,557E-03 0,02970989 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,557E-03 0,02965404 ! negative regulation of B cell activation GO:0050869 13 6 0,000 6,557E-03 0,0295984 ! protein amino acid prenylation GO:0018346 16 6 0,000 6,557E-03 0,02954298 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,557E-03 0,02948776 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 6,557E-03 0,02943274 ! positive regulation of coagulation GO:0050820 12 6 0,000 6,557E-03 0,02937793 ! tRNA transcription GO:0009304 14 7 0,000 7,646E-03 0,03419239 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 7,646E-03 0,03412895 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 7,646E-03 0,03406575 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,646E-03 0,03400278 ! regulation of helicase activity GO:0051095 15 7 0,000 7,646E-03 0,03394004 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,646E-03 0,03387754 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 7,646E-03 0,03381526 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 7,646E-03 0,03375322 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,646E-03 0,0336914 ! prostate gland development GO:0030850 13 7 0,000 7,646E-03 0,0336298 ! nucleotide-sugar transport GO:0015780 12 7 0,000 7,646E-03 0,03356844 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,646E-03 0,03350729 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,646E-03 0,03344637 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 7,646E-03 0,03338567 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,646E-03 0,03332519 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 7,646E-03 0,03326492 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 7,646E-03 0,03320488 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 7,646E-03 0,03314505 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 7,646E-03 0,03308544 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 7,646E-03 0,03302604 ! glycolipid transport GO:0046836 10 7 0,000 7,646E-03 0,03296685 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,646E-03 0,03290788 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,646E-03 0,03284911 ! neuron adhesion GO:0007158 12 7 0,000 7,646E-03 0,03279056 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 7,646E-03 0,03273221 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,646E-03 0,03267407 ! actin-myosin filament sliding GO:0033275 11 7 0,000 7,646E-03 0,03261614 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 7,646E-03 0,03255841 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 7,646E-03 0,03250089 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 7,646E-03 0,03244357 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 7,646E-03 0,03238645 ! mRNA stabilization GO:0048255 18 7 0,000 7,646E-03 0,03232953 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 7,646E-03 0,03227281 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 7,646E-03 0,03221629 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 7,646E-03 0,03215997 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,646E-03 0,03210385 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,646E-03 0,03204792 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,646E-03 0,03199218 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,646E-03 0,03193664 ! lipoprotein transport GO:0042953 14 7 0,000 7,646E-03 0,03188129 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,646E-03 0,03182613 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,646E-03 0,03177116 ! rhythmic behavior GO:0007622 15 7 0,000 7,646E-03 0,03171638 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 7,646E-03 0,0316618 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 7,646E-03 0,03160739 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 7,646E-03 0,03155318 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,646E-03 0,03149915 ! regulation of odontogenesis GO:0042481 13 7 0,000 7,646E-03 0,0314453 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,646E-03 0,03139164 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 7,646E-03 0,03133817 ! mechanosensory behavior GO:0007638 14 7 0,000 7,646E-03 0,03128487 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 7,646E-03 0,03123175 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,646E-03 0,03117882 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 7,646E-03 0,03112606 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,646E-03 0,03107349 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,646E-03 0,03102108 ! spinal cord patterning GO:0021511 13 7 0,000 7,646E-03 0,03096886 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 7,646E-03 0,03091681 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,646E-03 0,03086494 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 7,646E-03 0,03081324 ! adrenal gland development GO:0030325 17 7 0,000 7,646E-03 0,03076171 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 7,646E-03 0,03071036 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 7,646E-03 0,03065917 ! ovulation GO:0030728 9 7 0,000 7,646E-03 0,03060816 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 7,646E-03 0,03055731 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,646E-03 0,03050664 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 7,646E-03 0,03045613 ! microtubule nucleation GO:0007020 20 7 0,000 7,646E-03 0,03040579 ! proline biosynthetic process GO:0006561 10 7 0,000 7,646E-03 0,03035562 ! thyroid hormone generation GO:0006590 13 7 0,000 7,646E-03 0,03030561 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 7,646E-03 0,03025576 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 7,646E-03 0,03020608 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 7,646E-03 0,03015656 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,646E-03 0,03010721 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,646E-03 0,03005801 ! galactose metabolic process GO:0006012 13 7 0,000 7,646E-03 0,03000898 ! vesicle fusion GO:0006906 17 7 0,000 7,646E-03 0,0299601 ! response to dietary excess GO:0002021 8 7 0,000 7,646E-03 0,02991139 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,646E-03 0,02986283 ! intracellular pH reduction GO:0051452 11 7 0,000 7,646E-03 0,02981443 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,646E-03 0,02976619 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 7,646E-03 0,0297181 ! organ growth GO:0035265 15 7 0,000 7,646E-03 0,02967017 ! purine salvage GO:0043101 10 7 0,000 7,646E-03 0,02962239 ! nucleoside transport GO:0015858 8 7 0,000 7,646E-03 0,02957476 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 7,646E-03 0,02952729 ! parturition GO:0007567 14 7 0,000 7,646E-03 0,02947997 ! rRNA modification GO:0000154 14 7 0,000 7,646E-03 0,02943281 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 7,646E-03 0,02938579 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 7,646E-03 0,02933892 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 7,646E-03 0,0292922 ! macrophage differentiation GO:0030225 11 7 0,000 7,646E-03 0,02924563 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,646E-03 0,02919921 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,646E-03 0,02915294 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 7,646E-03 0,02910681 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,646E-03 0,02906083 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 7,646E-03 0,02901499 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,646E-03 0,0289693 ! fibrinolysis GO:0042730 10 7 0,000 7,646E-03 0,02892375 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 7,646E-03 0,02887834 ! eating behavior GO:0042755 7 7 0,000 7,646E-03 0,02883308 ! B cell lineage commitment GO:0002326 21 7 0,000 7,646E-03 0,02878796 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,646E-03 0,02874297 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 7,646E-03 0,02869813 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 7,646E-03 0,02865343 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,646E-03 0,02860887 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 7,646E-03 0,02856445 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,646E-03 0,02852016 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 7,646E-03 0,02847601 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 7,646E-03 0,028432 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 7,646E-03 0,02838812 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 7,646E-03 0,02834438 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,646E-03 0,02830077 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 7,646E-03 0,0282573 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,646E-03 0,02821396 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,646E-03 0,02817076 ! regulation of meiosis GO:0040020 12 7 0,000 7,646E-03 0,02812768 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 7,646E-03 0,02808474 ! T cell lineage commitment GO:0002360 16 7 0,000 7,646E-03 0,02804193 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 7,646E-03 0,02799924 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,646E-03 0,02795669 ! oxygen homeostasis GO:0032364 12 7 0,000 7,646E-03 0,02791427 ! transcription termination GO:0006353 13 7 0,000 7,646E-03 0,02787197 ! response to tumor cell GO:0002347 13 7 0,000 7,646E-03 0,02782981 ! regulation of respiratory burst GO:0060263 11 7 0,000 7,646E-03 0,02778777 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,646E-03 0,02774586 ! anaphase GO:0051322 17 7 0,000 7,646E-03 0,02770407 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 7,646E-03 0,02766241 ! axonal fasciculation GO:0007413 18 7 0,000 7,646E-03 0,02762088 ! negative regulation of nuclear division GO:0051784 14 7 0,000 7,646E-03 0,02757947 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 7,646E-03 0,02753818 ! peptidyl-threonine modification GO:0018210 25 7 0,000 7,646E-03 0,02749702 ! diuresis GO:0030146 12 7 0,000 7,646E-03 0,02745598 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,646E-03 0,02741506 ! thiamin metabolic process GO:0006772 7 7 0,000 7,646E-03 0,02737426 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,646E-03 0,02733359 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 7,646E-03 0,02729303 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 7,646E-03 0,0272526 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,646E-03 0,02721228 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,646E-03 0,02717209 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,646E-03 0,02713201 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,646E-03 0,02709205 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 7,646E-03 0,02705221 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,646E-03 0,02701249 ! glycolipid catabolic process GO:0019377 15 7 0,000 7,646E-03 0,02697288 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,646E-03 0,02693339 ! lymph node development GO:0048535 10 7 0,000 7,646E-03 0,02689401 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 7,646E-03 0,02685475 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,646E-03 0,0268156 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 7,646E-03 0,02677657 ! endosome to lysosome transport GO:0008333 11 7 0,000 7,646E-03 0,02673765 ! protein modification by small protein removal GO:0070646 16 7 0,000 7,646E-03 0,02669884 ! adult feeding behavior GO:0008343 9 7 0,000 7,646E-03 0,02666015 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 7,646E-03 0,02662157 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 7,646E-03 0,0265831 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,646E-03 0,02654474 ! muscle adaptation GO:0043500 14 7 0,000 7,646E-03 0,02650649 ! embryonic heart tube development GO:0035050 10 7 0,000 7,646E-03 0,02646835 ! retina homeostasis GO:0001895 12 7 0,000 7,646E-03 0,02643032 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,646E-03 0,0263924 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 7,646E-03 0,02635459 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 7,646E-03 0,02631689 ! protein prenylation GO:0018342 18 7 0,000 7,646E-03 0,02627929 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 7,646E-03 0,0262418 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 7,646E-03 0,02620442 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,646E-03 0,02616715 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 8,733E-03 0,02984698 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 8,733E-03 0,02980464 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 8,733E-03 0,02976243 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 8,733E-03 0,02972033 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 8,733E-03 0,02967835 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,733E-03 0,02963649 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,733E-03 0,02959475 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 8,733E-03 0,02955313 ! neutral lipid catabolic process GO:0046461 13 8 0,000 8,733E-03 0,02951162 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 8,733E-03 0,02947023 ! meiotic prophase I GO:0007128 13 8 0,000 8,733E-03 0,02942895 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,733E-03 0,02938779 ! oligopeptide transport GO:0006857 15 8 0,000 8,733E-03 0,02934675 ! UTP metabolic process GO:0046051 8 8 0,000 8,733E-03 0,02930582 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 8,733E-03 0,029265 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 8,733E-03 0,0292243 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 8,733E-03 0,02918371 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,733E-03 0,02914324 ! succinate metabolic process GO:0006105 14 8 0,000 8,733E-03 0,02910287 ! membrane hyperpolarization GO:0060081 10 8 0,000 8,733E-03 0,02906262 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,733E-03 0,02902248 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 8,733E-03 0,02898245 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,733E-03 0,02894253 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 8,733E-03 0,02890271 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,733E-03 0,02886301 ! ganglioside metabolic process GO:0001573 19 8 0,000 8,733E-03 0,02882342 ! reflex GO:0060004 16 8 0,000 8,733E-03 0,02878394 ! negative regulation of endocytosis GO:0045806 11 8 0,000 8,733E-03 0,02874456 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 8,733E-03 0,02870529 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,733E-03 0,02866613 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 8,733E-03 0,02862708 ! glycerolipid catabolic process GO:0046503 13 8 0,000 8,733E-03 0,02858813 ! hemoglobin metabolic process GO:0020027 13 8 0,000 8,733E-03 0,02854928 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,733E-03 0,02851055 ! pigment granule organization GO:0048753 16 8 0,000 8,733E-03 0,02847192 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,733E-03 0,02843339 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 8,733E-03 0,02839496 ! astrocyte differentiation GO:0048708 18 8 0,000 8,733E-03 0,02835664 ! histidine metabolic process GO:0006547 16 8 0,000 8,733E-03 0,02831843 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 8,733E-03 0,02828031 ! glycine catabolic process GO:0006546 13 8 0,000 8,733E-03 0,0282423 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 8,733E-03 0,02820439 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 8,733E-03 0,02816659 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 8,733E-03 0,02812888 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 8,733E-03 0,02809127 ! regulation of pigmentation during development GO:0048070 24 8 0,000 8,733E-03 0,02805377 ! melanin metabolic process GO:0006582 15 8 0,000 8,733E-03 0,02801636 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 8,733E-03 0,02797906 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 8,733E-03 0,02794185 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,733E-03 0,02790475 ! macrophage activation GO:0042116 12 8 0,000 8,733E-03 0,02786774 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,733E-03 0,02783083 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,733E-03 0,02779401 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 8,733E-03 0,0277573 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,733E-03 0,02772068 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,733E-03 0,02768415 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 8,733E-03 0,02764773 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,733E-03 0,0276114 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 8,733E-03 0,02757516 ! osteoblast development GO:0002076 16 8 0,000 8,733E-03 0,02753902 ! positive regulation of vasodilation GO:0045909 13 8 0,000 8,733E-03 0,02750298 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,733E-03 0,02746702 ! negative regulation of translational initiation GO:0045947 10 8 0,000 8,733E-03 0,02743117 ! Schwann cell differentiation GO:0014037 19 8 0,000 8,733E-03 0,0273954 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 8,733E-03 0,02735973 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,733E-03 0,02732415 ! response to UV-B GO:0010224 16 8 0,000 8,733E-03 0,02728867 ! protein targeting to vacuole GO:0006623 12 8 0,000 8,733E-03 0,02725327 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,733E-03 0,02721797 ! intermediate filament organization GO:0045109 12 8 0,000 8,733E-03 0,02718276 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 8,733E-03 0,02714764 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 8,733E-03 0,02711261 ! cellular extravasation GO:0045123 12 8 0,000 8,733E-03 0,02707767 ! cardiac muscle cell development GO:0055013 13 8 0,000 8,733E-03 0,02704282 ! regulation of circadian rhythm GO:0042752 16 8 0,000 8,733E-03 0,02700806 ! response to antibiotic GO:0046677 11 8 0,000 8,733E-03 0,02697339 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 8,733E-03 0,02693881 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 8,733E-03 0,02690432 ! response to tropane GO:0014073 15 8 0,000 8,733E-03 0,02686991 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 8,733E-03 0,0268356 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 8,733E-03 0,02680137 ! melanosome transport GO:0032402 13 8 0,000 8,733E-03 0,02676723 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 8,733E-03 0,02673317 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 8,733E-03 0,0266992 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,733E-03 0,02666532 ! multicellular organismal aging GO:0010259 18 8 0,000 8,733E-03 0,02663153 ! dendrite morphogenesis GO:0048813 13 8 0,000 8,733E-03 0,02659781 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 8,733E-03 0,02656419 ! nucleosome disassembly GO:0006337 14 8 0,000 8,733E-03 0,02653065 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,733E-03 0,02649719 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 8,733E-03 0,02646382 ! leukocyte activation during immune response GO:0002366 13 8 0,000 8,733E-03 0,02643053 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,733E-03 0,02639733 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 8,733E-03 0,02636421 ! intracellular lipid transport GO:0032365 13 8 0,000 8,733E-03 0,02633117 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,733E-03 0,02629821 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 8,733E-03 0,02626534 ! regulation of macrophage activation GO:0043030 15 8 0,000 8,733E-03 0,02623255 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 8,733E-03 0,02619984 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,733E-03 0,02616721 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 8,733E-03 0,02613467 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 8,733E-03 0,0261022 ! hormone catabolic process GO:0042447 17 8 0,000 8,733E-03 0,02606982 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,733E-03 0,02603751 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 8,733E-03 0,02600529 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 8,733E-03 0,02597314 ! ATP catabolic process GO:0006200 11 8 0,000 8,733E-03 0,02594108 ! blastocyst growth GO:0001832 19 8 0,000 8,733E-03 0,02590909 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,733E-03 0,02587718 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,733E-03 0,02584535 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 8,733E-03 0,0258136 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,733E-03 0,02578193 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 8,733E-03 0,02575034 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 8,733E-03 0,02571882 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 8,733E-03 0,02568738 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 8,733E-03 0,02565601 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 8,733E-03 0,02562472 ! amino sugar catabolic process GO:0046348 10 8 0,000 8,733E-03 0,02559351 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 8,733E-03 0,02556238 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,733E-03 0,02553132 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,733E-03 0,02550033 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,733E-03 0,02546942 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,733E-03 0,02543859 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,733E-03 0,02540783 ! NAD biosynthetic process GO:0009435 13 8 0,000 8,733E-03 0,02537714 ! regulation of developmental growth GO:0048638 15 9 0,000 9,82E-03 0,02849971 ! axon extension GO:0048675 15 9 0,000 9,82E-03 0,02846538 ! autophagic vacuole formation GO:0000045 15 9 0,000 9,82E-03 0,02843112 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,82E-03 0,02839695 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 9,82E-03 0,02836286 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 9,82E-03 0,02832885 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,82E-03 0,02829493 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 9,82E-03 0,02826108 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 9,82E-03 0,02822731 ! cell proliferation in forebrain GO:0021846 15 9 0,000 9,82E-03 0,02819363 ! phosphate transport GO:0006817 19 9 0,000 9,82E-03 0,02816003 ! reproductive behavior GO:0019098 19 9 0,000 9,82E-03 0,0281265 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,82E-03 0,02809306 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 9,82E-03 0,02805969 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 9,82E-03 0,02802641 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 9,82E-03 0,0279932 ! GTP metabolic process GO:0046039 9 9 0,000 9,82E-03 0,02796007 ! RNA methylation GO:0001510 15 9 0,000 9,82E-03 0,02792702 ! elastic fiber assembly GO:0048251 15 9 0,000 9,82E-03 0,02789405 ! induction of positive chemotaxis GO:0050930 15 9 0,000 9,82E-03 0,02786116 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 9,82E-03 0,02782834 ! artery development GO:0060840 24 9 0,000 9,82E-03 0,0277956 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 9,82E-03 0,02776294 ! regulation of glycolysis GO:0006110 21 9 0,000 9,82E-03 0,02773035 ! cerebral cortex cell migration GO:0021795 15 9 0,000 9,82E-03 0,02769785 ! keratinocyte proliferation GO:0043616 14 9 0,000 9,82E-03 0,02766541 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 9,82E-03 0,02763306 ! chemosensory behavior GO:0007635 20 9 0,000 9,82E-03 0,02760077 ! microtubule bundle formation GO:0001578 21 9 0,000 9,82E-03 0,02756857 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,82E-03 0,02753644 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 9,82E-03 0,02750438 ! leukocyte degranulation GO:0043299 16 9 0,000 9,82E-03 0,0274724 ! bile acid and bile salt transport GO:0015721 13 9 0,000 9,82E-03 0,02744049 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 9,82E-03 0,02740866 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 9,82E-03 0,0273769 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,82E-03 0,02734521 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,82E-03 0,0273136 ! protein targeting to ER GO:0045047 22 9 0,000 9,82E-03 0,02728206 ! ceramide biosynthetic process GO:0046513 19 9 0,000 9,82E-03 0,02725059 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 9,82E-03 0,0272192 ! T cell selection GO:0045058 23 9 0,000 9,82E-03 0,02718787 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 9,82E-03 0,02715662 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 9,82E-03 0,02712544 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,82E-03 0,02709434 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 9,82E-03 0,0270633 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 9,82E-03 0,02703234 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,82E-03 0,02700144 ! mannose metabolic process GO:0006013 13 9 0,000 9,82E-03 0,02697062 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 9,82E-03 0,02693987 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 9,82E-03 0,02690918 ! Rac protein signal transduction GO:0016601 17 9 0,000 9,82E-03 0,02687857 ! receptor clustering GO:0043113 18 9 0,000 9,82E-03 0,02684803 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 9,82E-03 0,02681755 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,82E-03 0,02678715 ! ruffle organization GO:0031529 15 9 0,000 9,82E-03 0,02675681 ! retinol metabolic process GO:0042572 18 9 0,000 9,82E-03 0,02672654 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 9,82E-03 0,02669634 ! behavioral fear response GO:0001662 22 9 0,000 9,82E-03 0,02666621 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 9,82E-03 0,02663615 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 9,82E-03 0,02660615 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 9,82E-03 0,02657622 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 9,82E-03 0,02654636 ! protein heterooligomerization GO:0051291 16 9 0,000 9,82E-03 0,02651657 ! oligodendrocyte development GO:0014003 10 9 0,000 9,82E-03 0,02648684 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 9,82E-03 0,02645718 ! segment specification GO:0007379 13 9 0,000 9,82E-03 0,02642759 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,82E-03 0,02639806 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 9,82E-03 0,0263686 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,82E-03 0,0263392 ! response to amine stimulus GO:0014075 13 9 0,000 9,82E-03 0,02630987 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,82E-03 0,0262806 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 9,82E-03 0,0262514 ! erythrocyte development GO:0048821 15 9 0,000 9,82E-03 0,02622227 ! gas homeostasis GO:0033483 16 9 0,000 9,82E-03 0,0261932 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,82E-03 0,02616419 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 9,82E-03 0,02613525 ! renal water homeostasis GO:0003091 14 9 0,000 9,82E-03 0,02610637 ! postreplication repair GO:0006301 22 9 0,000 9,82E-03 0,02607755 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 9,82E-03 0,0260488 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 9,82E-03 0,02602011 ! icosanoid secretion GO:0032309 15 9 0,000 9,82E-03 0,02599149 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 9,82E-03 0,02596293 ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,82E-03 0,02593443 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 9,82E-03 0,02590599 ! regulation of cell division GO:0051302 15 9 0,000 9,82E-03 0,02587761 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 9,82E-03 0,0258493 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 9,82E-03 0,02582105 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,82E-03 0,02579286 ! sterol catabolic process GO:0016127 11 9 0,000 9,82E-03 0,02576474 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,82E-03 0,02573667 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 9,82E-03 0,02570866 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 9,82E-03 0,02568072 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 9,82E-03 0,02565284 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 9,82E-03 0,02562501 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 9,82E-03 0,02559725 ! musculoskeletal movement GO:0050881 14 9 0,000 9,82E-03 0,02556955 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 9,82E-03 0,02554191 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 9,82E-03 0,02551432 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,82E-03 0,0254868 ! purine base metabolic process GO:0006144 21 9 0,000 9,82E-03 0,02545933 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 9,82E-03 0,02543193 ! pigment granule transport GO:0051904 17 9 0,000 9,82E-03 0,02540458 ! regulation of fibrinolysis GO:0051917 16 9 0,000 9,82E-03 0,0253773 ! regulation of telomere maintenance GO:0032204 14 9 0,000 9,82E-03 0,02535007 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 9,82E-03 0,0253229 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,82E-03 0,02529578 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,82E-03 0,02526873 ! mitochondrion localization GO:0051646 15 9 0,000 9,82E-03 0,02524173 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01090502 0,02800157 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01090502 0,02797172 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01090502 0,02794193 ! synapsis GO:0007129 13 10 0,000 0,01090502 0,02791221 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01090502 0,02788254 ! N-glycan processing GO:0006491 20 10 0,000 0,01090502 0,02785294 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01090502 0,02782341 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01090502 0,02779393 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01090502 0,02776452 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01090502 0,02773517 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01090502 0,02770589 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01090502 0,02767666 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01090502 0,0276475 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01090502 0,02761839 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01090502 0,02758935 ! androgen metabolic process GO:0008209 17 10 0,000 0,01090502 0,02756037 ! phospholipid efflux GO:0033700 16 10 0,000 0,01090502 0,02753145 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01090502 0,02750259 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01090502 0,02747379 ! lung alveolus development GO:0048286 26 10 0,000 0,01090502 0,02744506 ! pathogenesis GO:0009405 13 10 0,000 0,01090502 0,02741638 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01090502 0,02738776 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01090502 0,0273592 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01090502 0,0273307 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01090502 0,02730226 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01090502 0,02727388 ! endoderm development GO:0007492 16 10 0,000 0,01090502 0,02724556 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01090502 0,0272173 ! arginine catabolic process GO:0006527 13 10 0,000 0,01090502 0,02718909 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01090502 0,02716095 ! proline metabolic process GO:0006560 13 10 0,000 0,01090502 0,02713286 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01090502 0,02710483 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01090502 0,02707686 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01090502 0,02704894 ! V(D)J recombination GO:0033151 28 10 0,000 0,01090502 0,02702108 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01090502 0,02699329 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01090502 0,02696554 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 0,01090502 0,02693786 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01090502 0,02691023 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01090502 0,02688266 ! multicellular organism growth GO:0035264 18 10 0,000 0,01090502 0,02685514 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01090502 0,02682768 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01090502 0,02680028 ! epithelial cell development GO:0002064 20 10 0,000 0,01090502 0,02677293 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01090502 0,02674564 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01090502 0,0267184 ! macroautophagy GO:0016236 17 10 0,000 0,01090502 0,02669122 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01090502 0,0266641 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01090502 0,02663703 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01090502 0,02661001 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01090502 0,02658305 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01090502 0,02655615 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01090502 0,0265293 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01090502 0,0265025 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01090502 0,02647575 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01090502 0,02644907 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01090502 0,02642243 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01090502 0,02639585 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01090502 0,02636932 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01090502 0,02634284 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01090502 0,02631642 ! response to dsRNA GO:0043331 20 10 0,000 0,01090502 0,02629005 ! DNA ligation GO:0006266 19 10 0,000 0,01090502 0,02626374 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01090502 0,02623747 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01090502 0,02621126 ! melanosome localization GO:0032400 16 10 0,000 0,01090502 0,0261851 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01090502 0,026159 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01090502 0,02613294 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01090502 0,02610694 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01090502 0,02608099 ! mRNA cleavage GO:0006379 17 10 0,000 0,01090502 0,02605509 ! protein sumoylation GO:0016925 15 10 0,000 0,01090502 0,02602924 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01090502 0,02600344 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01090502 0,0259777 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01090502 0,025952 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01090502 0,02592636 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01090502 0,02590076 ! salivary gland development GO:0007431 27 10 0,000 0,01090502 0,02587522 ! prophase GO:0051324 15 10 0,000 0,01090502 0,02584973 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01090502 0,02582428 ! apical protein localization GO:0045176 15 10 0,000 0,01090502 0,02579889 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01090502 0,02577355 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01090502 0,02574826 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01090502 0,02572301 ! midbrain development GO:0030901 13 10 0,000 0,01090502 0,02569782 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01090502 0,02567267 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01090502 0,02564758 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01090502 0,02562253 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01090502 0,02559753 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01090502 0,02557259 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01090502 0,02554769 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01090502 0,02552283 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01090502 0,02549803 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01090502 0,02547327 ! oocyte development GO:0048599 17 10 0,000 0,01090502 0,02544857 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01090502 0,02542391 ! blastocyst formation GO:0001825 17 10 0,000 0,01090502 0,0253993 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01090502 0,02537473 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01090502 0,02535022 ! activation of innate immune response GO:0002218 12 10 0,000 0,01090502 0,02532575 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01090502 0,02530132 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01090502 0,02527695 ! response to nicotine GO:0035094 20 10 0,000 0,01090502 0,02525262 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01090502 0,02522834 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01090502 0,0252041 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01090502 0,02517992 ! localization within membrane GO:0051668 20 10 0,000 0,01090502 0,02515577 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01198916 0,02763018 ! respiratory burst GO:0045730 17 11 0,000 0,01198916 0,02760374 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01198916 0,02757735 ! neuron fate specification GO:0048665 17 11 0,000 0,01198916 0,02755101 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01198916 0,02752472 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01198916 0,02749848 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01198916 0,02747229 ! thyroid gland development GO:0030878 26 11 0,000 0,01198916 0,02744615 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01198916 0,02742007 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01198916 0,02739403 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01198916 0,02736803 ! response to pain GO:0048265 24 11 0,000 0,01198916 0,02734209 ! T cell proliferation GO:0042098 26 11 0,000 0,01198916 0,0273162 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01198916 0,02729036 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01198916 0,02726456 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01198916 0,02723882 ! bone resorption GO:0045453 16 11 0,000 0,01198916 0,02721312 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01198916 0,02718747 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01198916 0,02716187 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01198916 0,02713632 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01198916 0,02711082 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01198916 0,02708536 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01198916 0,02705995 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01198916 0,02703459 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01198916 0,02700928 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01198916 0,02698401 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01198916 0,02695879 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01198916 0,02693362 ! lipid digestion GO:0044241 18 11 0,000 0,01198916 0,0269085 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01198916 0,02688342 ! UV protection GO:0009650 19 11 0,000 0,01198916 0,02685839 ! adult heart development GO:0007512 14 11 0,000 0,01198916 0,0268334 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01198916 0,02680847 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01198916 0,02678357 ! temperature homeostasis GO:0001659 17 11 0,000 0,01198916 0,02675873 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01198916 0,02673393 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01198916 0,02670917 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01198916 0,02668447 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01198916 0,0266598 ! regulation of organ growth GO:0046620 13 11 0,000 0,01198916 0,02663519 ! pigment granule localization GO:0051875 20 11 0,000 0,01198916 0,02661062 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01198916 0,02658609 ! vasoconstriction GO:0042310 18 11 0,000 0,01198916 0,02656161 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01198916 0,02653717 ! embryonic axis specification GO:0000578 18 11 0,000 0,01198916 0,02651278 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01198916 0,02648844 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01198916 0,02646414 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01198916 0,02643988 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01198916 0,02641567 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01198916 0,0263915 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01198916 0,02636738 ! zymogen activation GO:0031638 15 11 0,000 0,01198916 0,0263433 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01198916 0,02631926 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01198916 0,02629527 ! nucleosome positioning GO:0016584 15 11 0,000 0,01198916 0,02627132 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01198916 0,02624741 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01198916 0,02622355 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01198916 0,02619974 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01198916 0,02617596 ! acid secretion GO:0046717 18 11 0,000 0,01198916 0,02615223 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01198916 0,02612854 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01198916 0,02610489 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01198916 0,02608129 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01198916 0,02605773 ! oocyte differentiation GO:0009994 18 11 0,000 0,01198916 0,02603421 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01198916 0,02601074 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01198916 0,0259873 ! cholesterol efflux GO:0033344 19 11 0,000 0,01198916 0,02596391 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01198916 0,02594057 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01198916 0,02591726 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01198916 0,02589399 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01198916 0,02587077 ! embryonic gut development GO:0048566 15 11 0,000 0,01198916 0,02584759 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01198916 0,02582445 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01198916 0,02580135 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01198916 0,02577829 ! defense response to fungus GO:0050832 13 11 0,000 0,01198916 0,02575528 ! developmental induction GO:0031128 19 11 0,000 0,01198916 0,0257323 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01198916 0,02570937 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01198916 0,02568647 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01198916 0,02566362 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01198916 0,02564081 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01198916 0,02561804 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01198916 0,0255953 ! nucleus localization GO:0051647 19 11 0,000 0,01198916 0,02557261 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01198916 0,02554996 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01307214 0,02783325 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01307214 0,02780864 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01307214 0,02778407 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01307214 0,02775955 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01307214 0,02773507 ! virus-host interaction GO:0019048 29 12 0,000 0,01307214 0,02771064 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01307214 0,02768624 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01307214 0,02766189 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01307214 0,02763758 ! protein complex disassembly GO:0043241 27 12 0,000 0,01307214 0,02761332 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01307214 0,0275891 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01307214 0,02756492 ! hippocampus development GO:0021766 26 12 0,000 0,01307214 0,02754078 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01307214 0,02751669 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01307214 0,02749263 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01307214 0,02746862 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01307214 0,02744465 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01307214 0,02742072 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01307214 0,02739684 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01307214 0,027373 ! drug transport GO:0015893 16 12 0,000 0,01307214 0,02734919 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01307214 0,02732543 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01307214 0,02730171 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01307214 0,02727803 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01307214 0,02725439 ! focal adhesion formation GO:0048041 35 12 0,000 0,01307214 0,0272308 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01307214 0,02720724 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01307214 0,02718373 ! forebrain cell migration GO:0021885 21 12 0,000 0,01307214 0,02716025 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01307214 0,02713682 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01307214 0,02711342 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01307214 0,02709007 ! entry into host cell GO:0030260 32 12 0,000 0,01307214 0,02706676 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01307214 0,02704348 ! monoamine transport GO:0015844 18 12 0,000 0,01307214 0,02702025 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01307214 0,02699706 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01307214 0,0269739 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01307214 0,02695079 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01307214 0,02692772 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01307214 0,02690468 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01307214 0,02688168 ! protein homotetramerization GO:0051289 21 12 0,000 0,01307214 0,02685873 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01307214 0,02683581 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01307214 0,02681293 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01307214 0,02679009 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01307214 0,02676729 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01307214 0,02674453 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01307214 0,02672181 ! cranial nerve development GO:0021545 20 12 0,000 0,01307214 0,02669913 ! fucose catabolic process GO:0019317 22 12 0,000 0,01307214 0,02667648 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01307214 0,02665387 ! histone acetylation GO:0016573 26 12 0,000 0,01307214 0,02663131 ! histone methylation GO:0016571 26 12 0,000 0,01307214 0,02660877 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01307214 0,02658628 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01307214 0,02656383 ! gland morphogenesis GO:0022612 29 12 0,000 0,01307214 0,02654141 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01307214 0,02651903 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01307214 0,02649669 ! T cell homeostasis GO:0043029 25 12 0,000 0,01307214 0,02647439 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01307214 0,02645212 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01307214 0,02642989 ! spleen development GO:0048536 22 12 0,000 0,01307214 0,0264077 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01307214 0,02638555 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01307214 0,02636343 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01307214 0,02634135 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01307214 0,02631931 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01307214 0,0262973 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01307214 0,02627533 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01307214 0,0262534 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01307214 0,0262315 ! response to cold GO:0009409 17 12 0,000 0,01307214 0,02620964 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01307214 0,02618782 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01307214 0,02616603 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01415398 0,02830795 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01415398 0,02828444 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01415398 0,02826097 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01415398 0,02823753 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01415398 0,02821414 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01415398 0,02819078 ! lipid localization GO:0010876 28 13 0,000 0,01415398 0,02816746 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01415398 0,02814419 ! organelle fusion GO:0048284 32 13 0,000 0,01415398 0,02812095 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01415398 0,02809774 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01415398 0,02807458 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01415398 0,02805145 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01415398 0,02802837 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01415398 0,02800532 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01415398 0,0279823 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01415398 0,02795933 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01415398 0,02793639 ! methionine metabolic process GO:0006555 27 13 0,000 0,01415398 0,0279135 ! plasma membrane organization GO:0007009 24 13 0,000 0,01415398 0,02789063 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01415398 0,02786781 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01415398 0,02784502 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01415398 0,02782227 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01415398 0,02779956 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01415398 0,02777689 ! response to X-ray GO:0010165 25 13 0,000 0,01415398 0,02775425 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01415398 0,02773165 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01415398 0,02770908 ! exocrine system development GO:0035272 32 13 0,000 0,01415398 0,02768656 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01415398 0,02766407 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01415398 0,02764161 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01415398 0,02761919 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01415398 0,02759681 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01415398 0,02757447 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01415398 0,02755216 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01415398 0,02752988 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01415398 0,02750764 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01415398 0,02748544 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01415398 0,02746328 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01415398 0,02744115 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01415398 0,02741905 ! ribosome assembly GO:0042255 17 13 0,000 0,01415398 0,02739699 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01415398 0,02737497 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01415398 0,02735298 ! chromatin silencing GO:0006342 26 13 0,000 0,01415398 0,02733103 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01415398 0,02730911 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01415398 0,02728723 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01415398 0,02726538 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01415398 0,02724357 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01415398 0,02722179 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01415398 0,02720005 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01415398 0,02717834 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01415398 0,02715667 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01415398 0,02713503 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01415398 0,02711343 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01415398 0,02709186 ! embryonic placenta development GO:0001892 23 13 0,000 0,01415398 0,02707032 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01415398 0,02704882 ! insulin secretion GO:0030073 23 13 0,000 0,01415398 0,02702735 ! actin filament polymerization GO:0030041 24 13 0,000 0,01415398 0,02700592 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01415398 0,02698452 ! acrosome reaction GO:0007340 18 13 0,000 0,01415398 0,02696315 ! rRNA transcription GO:0009303 25 14 0,000 0,01523466 0,02899889 ! lactation GO:0007595 26 14 0,000 0,01523466 0,02897596 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01523466 0,02895307 ! reproductive cellular process GO:0048610 20 14 0,000 0,01523466 0,02893022 ! tRNA modification GO:0006400 20 14 0,000 0,01523466 0,02890741 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01523466 0,02888463 ! regulation of S phase GO:0033261 23 14 0,000 0,01523466 0,02886188 ! water transport GO:0006833 21 14 0,000 0,01523466 0,02883917 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01523466 0,0288165 ! non-recombinational repair GO:0000726 25 14 0,000 0,01523466 0,02879387 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01523466 0,02877126 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01523466 0,0287487 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01523466 0,02872617 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01523466 0,02870367 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01523466 0,02868121 ! palate development GO:0060021 31 14 0,000 0,01523466 0,02865879 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01523466 0,0286364 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01523466 0,02861404 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01523466 0,02859172 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01523466 0,02856944 ! arginine metabolic process GO:0006525 17 14 0,000 0,01523466 0,02854719 ! regulation of heart rate GO:0002027 24 14 0,000 0,01523466 0,02852497 ! organic alcohol transport GO:0015850 29 14 0,000 0,01523466 0,02850279 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01523466 0,02848065 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01523466 0,02845853 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01523466 0,02843646 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01523466 0,02841441 ! L-amino acid transport GO:0015807 30 14 0,000 0,01523466 0,0283924 ! bone mineralization GO:0030282 17 14 0,000 0,01523466 0,02837043 ! stem cell development GO:0048864 43 14 0,000 0,01523466 0,02834848 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01523466 0,02832658 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01523466 0,0283047 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01523466 0,02828286 ! cerebellum development GO:0021549 21 14 0,000 0,01523466 0,02826106 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01523466 0,02823928 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01523466 0,02821754 ! response to gamma radiation GO:0010332 28 14 0,000 0,01523466 0,02819584 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01523466 0,02817417 ! cofactor transport GO:0051181 26 14 0,000 0,01523466 0,02815253 ! NADP metabolic process GO:0006739 24 14 0,000 0,01523466 0,02813092 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01523466 0,02810935 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01523466 0,02808781 ! intestinal absorption GO:0050892 25 14 0,000 0,01523466 0,0280663 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01523466 0,02804483 ! oxygen transport GO:0015671 21 14 0,000 0,01523466 0,02802339 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01523466 0,02800198 ! male genitalia development GO:0030539 24 14 0,000 0,01523466 0,0279806 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01523466 0,02795926 ! regulation of axon extension GO:0030516 37 14 0,000 0,01523466 0,02793795 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01523466 0,02791667 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01523466 0,02789543 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01631419 0,02984939 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01631419 0,02982671 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01631419 0,02980406 ! superoxide anion generation GO:0042554 20 15 0,000 0,01631419 0,02978145 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01631419 0,02975887 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01631419 0,02973633 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01631419 0,02971382 ! copper ion transport GO:0006825 20 15 0,000 0,01631419 0,02969134 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01631419 0,0296689 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01631419 0,02964649 ! sulfate transport GO:0008272 23 15 0,000 0,01631419 0,02962412 ! response to cAMP GO:0051591 22 15 0,000 0,01631419 0,02960177 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01631419 0,02957947 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01631419 0,02955719 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01631419 0,02953495 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01631419 0,02951275 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01631419 0,02949057 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01631419 0,02946843 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01631419 0,02944633 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01631419 0,02942425 ! pituitary gland development GO:0021983 29 15 0,000 0,01631419 0,02940221 ! vesicle coating GO:0006901 33 15 0,000 0,01631419 0,0293802 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01631419 0,02935823 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01631419 0,02933629 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01631419 0,02931438 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01631419 0,0292925 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01631419 0,02927066 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01631419 0,02924885 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01631419 0,02922707 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01631419 0,02920532 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01631419 0,02918361 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01631419 0,02916193 ! histone deacetylation GO:0016575 20 15 0,000 0,01631419 0,02914028 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01631419 0,02911866 ! tissue regeneration GO:0042246 26 15 0,000 0,01631419 0,02909707 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01631419 0,02907552 ! water homeostasis GO:0030104 27 15 0,000 0,01631419 0,029054 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01631419 0,02903251 ! muscle maintenance GO:0046716 26 15 0,000 0,01631419 0,02901105 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01631419 0,02898963 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01631419 0,02896823 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01631419 0,02894687 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01631419 0,02892554 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01631419 0,02890424 ! cell killing GO:0001906 29 15 0,000 0,01631419 0,02888297 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01631419 0,02886173 ! detection of bacterium GO:0016045 18 15 0,000 0,01631419 0,02884052 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01631419 0,02881935 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01631419 0,0287982 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01631419 0,02877709 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01631419 0,02875601 ! peptide hormone processing GO:0016486 23 15 0,000 0,01631419 0,02873496 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01739258 0,03061196 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01739258 0,03058959 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01739258 0,03056724 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01739258 0,03054493 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01739258 0,03052265 ! bone remodeling GO:0046849 27 16 0,000 0,01739258 0,0305004 ! filopodium assembly GO:0046847 32 16 0,000 0,01739258 0,03047819 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01739258 0,03045601 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01739258 0,03043386 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01739258 0,03041174 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01739258 0,03038965 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01739258 0,0303676 ! startle response GO:0001964 28 16 0,000 0,01739258 0,03034558 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01739258 0,03032359 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01739258 0,03030163 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01739258 0,03027971 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01739258 0,03025781 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01739258 0,03023595 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01739258 0,03021412 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01739258 0,03019232 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01739258 0,03017055 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01739258 0,03014881 ! response to osmotic stress GO:0006970 25 16 0,000 0,01739258 0,03012711 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01739258 0,03010543 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01739258 0,03008379 ! fructose metabolic process GO:0006000 25 16 0,000 0,01739258 0,03006218 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01739258 0,0300406 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01739258 0,03001905 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01739258 0,02999753 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01739258 0,02997604 ! axon cargo transport GO:0008088 43 16 0,000 0,01739258 0,02995458 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01739258 0,02993316 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01739258 0,02991176 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01739258 0,0298904 ! DNA replication initiation GO:0006270 27 16 0,000 0,01739258 0,02986906 ! neuron recognition GO:0008038 35 16 0,000 0,01739258 0,02984776 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01739258 0,02982648 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01739258 0,02980524 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01739258 0,02978402 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01739258 0,02976284 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01739258 0,02974169 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01739258 0,02972056 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01739258 0,02969947 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01739258 0,02967841 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01739258 0,02965737 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01739258 0,02963637 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01739258 0,0296154 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01739258 0,02959445 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01739258 0,02957354 ! defense response to virus GO:0051607 37 16 0,000 0,01739258 0,02955265 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01846982 0,0313609 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01846982 0,03133879 ! metencephalon development GO:0022037 30 17 0,000 0,01846982 0,0313167 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01846982 0,03129465 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01846982 0,03127262 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01846982 0,03125063 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01846982 0,03122867 ! signal complex assembly GO:0007172 41 17 0,000 0,01846982 0,03120674 ! endothelial cell migration GO:0043542 28 17 0,000 0,01846982 0,03118484 ! inositol metabolic process GO:0006020 28 17 0,000 0,01846982 0,03116297 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01846982 0,03114113 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01846982 0,03111933 ! glial cell development GO:0021782 27 17 0,000 0,01846982 0,03109755 ! limbic system development GO:0021761 36 17 0,000 0,01846982 0,0310758 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01846982 0,03105409 ! adult walking behavior GO:0007628 33 17 0,000 0,01846982 0,0310324 ! heart looping GO:0001947 30 17 0,000 0,01846982 0,03101074 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01846982 0,03098912 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01846982 0,03096752 ! myoblast differentiation GO:0045445 45 17 0,000 0,01846982 0,03094596 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01846982 0,03092442 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01846982 0,03090292 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01846982 0,03088144 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01846982 0,03086 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01846982 0,03083858 ! glycine metabolic process GO:0006544 28 17 0,000 0,01846982 0,0308172 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01846982 0,03079584 ! NAD metabolic process GO:0019674 29 17 0,000 0,01846982 0,03077451 ! membrane budding GO:0006900 37 17 0,000 0,01846982 0,03075322 ! DNA integration GO:0015074 29 17 0,000 0,01846982 0,03073195 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01846982 0,03071071 ! regulation of protein binding GO:0043393 33 17 0,000 0,01846982 0,0306895 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01846982 0,03066832 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01846982 0,03064717 ! genitalia development GO:0048806 30 17 0,000 0,01846982 0,03062605 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01846982 0,03060496 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01846982 0,03058389 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01846982 0,03056286 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01846982 0,03054185 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01846982 0,03052088 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01846982 0,03049993 ! steroid catabolic process GO:0006706 31 17 0,000 0,01846982 0,03047901 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01846982 0,03045812 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01846982 0,03043726 ! gas transport GO:0015669 25 17 0,000 0,01846982 0,03041643 ! organic cation transport GO:0015695 31 17 0,000 0,01846982 0,03039562 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01846982 0,03037484 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01846982 0,0303541 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01846982 0,03033338 ! microspike assembly GO:0030035 36 17 0,000 0,01846982 0,03031269 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01846982 0,03029202 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01846982 0,03027139 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01954592 0,03201326 ! neuron maturation GO:0042551 42 18 0,000 0,01954592 0,03199149 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01954592 0,03196974 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01954592 0,03194802 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01954592 0,03192633 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01954592 0,03190467 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01954592 0,03188304 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01954592 0,03186144 ! memory GO:0007613 31 18 0,000 0,01954592 0,03183987 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01954592 0,03181833 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01954592 0,03179681 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01954592 0,03177533 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01954592 0,03175387 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01954592 0,03173245 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01954592 0,03171105 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01954592 0,03168968 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01954592 0,03166834 ! response to retinoic acid GO:0032526 26 18 0,000 0,01954592 0,03164703 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01954592 0,03162575 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01954592 0,03160449 ! response to fungus GO:0009620 21 18 0,000 0,01954592 0,03158327 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01954592 0,03156207 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01954592 0,0315409 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01954592 0,03151976 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01954592 0,03149865 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01954592 0,03147757 ! vitamin transport GO:0051180 27 18 0,000 0,01954592 0,03145651 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01954592 0,03143548 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01954592 0,03141449 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01954592 0,03139351 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01954592 0,03137257 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01954592 0,03135166 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01954592 0,03133077 ! nerve development GO:0021675 28 18 0,000 0,01954592 0,03130991 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01954592 0,03128908 ! protein secretion GO:0009306 39 19 0,000 0,02062087 0,03298791 ! positive regulation of translation GO:0045727 30 19 0,000 0,02062087 0,03296599 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02062087 0,0329441 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02062087 0,03292224 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02062087 0,03290041 ! skin development GO:0043588 36 19 0,000 0,02062087 0,03287861 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02062087 0,03285683 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02062087 0,03283509 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02062087 0,03281337 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02062087 0,03279169 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02062087 0,03277003 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02062087 0,0327484 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02062087 0,03272679 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02062087 0,03270522 ! cerebral cortex development GO:0021987 36 19 0,000 0,02062087 0,03268368 ! pigmentation during development GO:0048066 41 19 0,000 0,02062087 0,03266216 ! response to vitamin A GO:0033189 27 19 0,000 0,02062087 0,03264067 ! heme metabolic process GO:0042168 36 19 0,000 0,02062087 0,03261921 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02062087 0,03259778 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02062087 0,03257638 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02062087 0,032555 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02062087 0,03253365 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02062087 0,03251233 ! protein export from nucleus GO:0006611 36 19 0,000 0,02062087 0,03249104 ! heart process GO:0003015 30 19 0,000 0,02062087 0,03246978 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02062087 0,03244854 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02062087 0,03242733 ! visual learning GO:0008542 36 19 0,000 0,02062087 0,03240615 ! cellular pigmentation GO:0033059 36 19 0,000 0,02062087 0,032385 ! G1 phase GO:0051318 40 19 0,000 0,02062087 0,03236387 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02062087 0,03234278 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02062087 0,03232171 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02062087 0,03230066 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02062087 0,03227965 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02062087 0,03225866 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02062087 0,0322377 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02062087 0,03221677 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02062087 0,03219586 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02062087 0,03217498 ! cilium assembly GO:0042384 37 19 0,000 0,02062087 0,03215413 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02062087 0,0321333 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02169468 0,03378473 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02169468 0,03376287 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02169468 0,03374105 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02169468 0,03371925 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02169468 0,03369749 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02169468 0,03367574 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,02169468 0,03365403 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02169468 0,03363235 ! response to vitamin GO:0033273 31 20 0,000 0,02169468 0,03361069 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02169468 0,03358906 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02169468 0,03356746 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02169468 0,03354589 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02169468 0,03352434 ! response to alkaloid GO:0043279 38 20 0,000 0,02169468 0,03350283 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02169468 0,03348134 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02169468 0,03345987 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02169468 0,03343844 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02169468 0,03341703 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02169468 0,03339565 ! cellular response to starvation GO:0009267 33 20 0,000 0,02169468 0,0333743 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02169468 0,03335297 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02169468 0,03333168 ! body fluid secretion GO:0007589 31 20 0,000 0,02169468 0,03331041 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02169468 0,03328916 ! peptide secretion GO:0002790 35 20 0,000 0,02169468 0,03326794 ! stem cell differentiation GO:0048863 53 20 0,000 0,02169468 0,03324675 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02169468 0,03322559 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02169468 0,03320446 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02169468 0,03318335 ! sensory perception of pain GO:0019233 30 20 0,000 0,02169468 0,03316226 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02169468 0,03314121 ! diencephalon development GO:0021536 34 20 0,000 0,02169468 0,03312018 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02169468 0,03309918 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02169468 0,0330782 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02169468 0,03305725 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02169468 0,03303633 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02169468 0,03301544 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02169468 0,03299457 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02169468 0,03297372 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02169468 0,03295291 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02169468 0,03293212 ! regulation of glucose import GO:0046324 29 20 0,000 0,02169468 0,03291135 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02169468 0,03289061 ! actin filament-based movement GO:0030048 43 20 0,000 0,02169468 0,0328699 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02169468 0,03284922 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02169468 0,03282856 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02169468 0,03280792 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02169468 0,03278731 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02169468 0,03276673 ! regulation of cell killing GO:0031341 42 21 0,000 0,02276735 0,03436527 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02276735 0,03434373 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02276735 0,03432221 ! hormone secretion GO:0046879 38 21 0,000 0,02276735 0,03430072 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02276735 0,03427925 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02276735 0,03425781 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02276735 0,0342364 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02276735 0,03421502 ! axis specification GO:0009798 38 21 0,000 0,02276735 0,03419366 ! ovarian follicle development GO:0001541 35 21 0,000 0,02276735 0,03417233 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02276735 0,03415102 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02276735 0,03412975 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02276735 0,03410849 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02276735 0,03408727 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02276735 0,03406607 ! cell aging GO:0007569 44 21 0,000 0,02276735 0,0340449 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02276735 0,03402375 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02276735 0,03400263 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02276735 0,03398154 ! cytolysis GO:0019835 24 21 0,000 0,02276735 0,03396047 ! vasodilation GO:0042311 39 21 0,000 0,02276735 0,03393943 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02276735 0,03391842 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02276735 0,03389743 ! oogenesis GO:0048477 36 21 0,000 0,02276735 0,03387646 ! DNA modification GO:0006304 34 21 0,000 0,02276735 0,03385553 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02276735 0,03383462 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02276735 0,03381373 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02276735 0,03379287 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02276735 0,03377204 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02276735 0,03375123 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02276735 0,03373045 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02276735 0,03370969 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02276735 0,03368896 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02276735 0,03366825 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02276735 0,03364757 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02276735 0,03362691 ! collagen catabolic process GO:0030574 28 21 0,000 0,02276735 0,03360628 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02276735 0,03358568 ! gut development GO:0048565 39 21 0,000 0,02276735 0,0335651 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02383888 0,03512329 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02383888 0,0351018 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02383888 0,03508033 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02383888 0,03505889 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02383888 0,03503747 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02383888 0,03501608 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02383888 0,03499471 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02383888 0,03497338 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02383888 0,03495206 ! regeneration GO:0031099 41 22 0,000 0,02383888 0,03493078 ! keratinization GO:0031424 28 22 0,000 0,02383888 0,03490952 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02383888 0,03488828 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02383888 0,03486707 ! sensory perception of taste GO:0050909 28 22 0,000 0,02383888 0,03484589 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02383888 0,03482473 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02383888 0,0348036 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02383888 0,0347825 ! vacuolar transport GO:0007034 36 22 0,000 0,02383888 0,03476142 ! lysosome organization GO:0007040 41 22 0,000 0,02383888 0,03474036 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02383888 0,03471933 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02383888 0,03469833 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02383888 0,03467735 ! fucose metabolic process GO:0006004 39 22 0,000 0,02383888 0,0346564 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02383888 0,03463547 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02383888 0,03461457 ! ureteric bud development GO:0001657 43 22 0,000 0,02383888 0,03459369 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02383888 0,03457284 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02383888 0,03455201 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02383888 0,03453121 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,02383888 0,03451043 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02383888 0,03448968 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02383888 0,03446895 ! sarcomere organization GO:0045214 30 22 0,000 0,02383888 0,03444825 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02383888 0,03442757 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02383888 0,03440692 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02383888 0,03438629 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02383888 0,03436569 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,02383888 0,03434511 ! protein stabilization GO:0050821 39 22 0,000 0,02383888 0,03432456 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02490926 0,03584431 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02490926 0,03582289 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,02490926 0,03580149 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,02490926 0,03578011 ! gluconeogenesis GO:0006094 33 23 0,000 0,02490926 0,03575876 ! viral genome replication GO:0019079 41 23 0,000 0,02490926 0,03573744 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02490926 0,03571614 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02490926 0,03569487 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02490926 0,03567362 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02490926 0,0356524 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02490926 0,03563121 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02490926 0,03561004 ! visual behavior GO:0007632 42 23 0,000 0,02490926 0,03558889 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02490926 0,03556777 ! response to ethanol GO:0045471 46 23 0,000 0,02490926 0,03554667 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02490926 0,0355256 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,02490926 0,03550456 ! peroxisome organization GO:0007031 37 23 0,000 0,02490926 0,03548353 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02490926 0,03546254 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02490926 0,03544157 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02490926 0,03542062 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02490926 0,0353997 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02490926 0,0353788 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02490926 0,03535793 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02490926 0,03533708 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02490926 0,03531626 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02490926 0,03529546 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02490926 0,03527468 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02490926 0,03525394 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02490926 0,03523321 ! fatty acid transport GO:0015908 44 23 0,000 0,02490926 0,03521251 ! platelet activation GO:0030168 37 23 0,000 0,02490926 0,03519183 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02490926 0,03517118 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02490926 0,03515055 ! hormone transport GO:0009914 40 23 0,000 0,02490926 0,03512995 ! cell-cell recognition GO:0009988 25 23 0,000 0,02490926 0,03510937 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02490926 0,03508881 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02490926 0,03506828 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02490926 0,03504777 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,02490926 0,03502729 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02490926 0,03500683 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02597851 0,03648821 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02597851 0,03646692 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02597851 0,03644566 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02597851 0,03642442 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02597851 0,03640321 ! vesicle docking GO:0048278 47 24 0,000 0,02597851 0,03638202 ! spinal cord development GO:0021510 47 24 0,000 0,02597851 0,03636085 ! vacuole organization GO:0007033 43 24 0,000 0,02597851 0,03633971 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02597851 0,0363186 ! digestive system process GO:0022600 39 24 0,000 0,02597851 0,03629751 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02597851 0,03627644 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02597851 0,0362554 ! regulation of behavior GO:0050795 43 24 0,000 0,02597851 0,03623438 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02597851 0,03621339 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02597851 0,03619242 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02597851 0,03617147 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02597851 0,03615055 ! membrane depolarization GO:0051899 39 24 0,000 0,02597851 0,03612966 ! pallium development GO:0021543 49 24 0,000 0,02597851 0,03610878 ! pentose metabolic process GO:0019321 35 24 0,000 0,02597851 0,03608794 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02597851 0,03606711 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02597851 0,03604631 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02597851 0,03602554 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02597851 0,03600478 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02597851 0,03598406 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02597851 0,03596335 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02597851 0,03594267 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02597851 0,03592201 ! regulation of amine transport GO:0051952 40 24 0,000 0,02597851 0,03590138 ! protein tetramerization GO:0051262 52 24 0,000 0,02597851 0,03588077 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02704663 0,03733459 ! myelination GO:0042552 45 25 0,000 0,02704663 0,03731318 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02704663 0,0372918 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02704663 0,03727044 ! phototransduction GO:0007602 33 25 0,000 0,02704663 0,0372491 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02704663 0,03722779 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02704663 0,03720651 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02704663 0,03718525 ! sperm motility GO:0030317 31 25 0,000 0,02704663 0,03716401 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02704663 0,0371428 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02704663 0,03712161 ! receptor metabolic process GO:0043112 46 25 0,000 0,02704663 0,03710045 ! chromosome condensation GO:0030261 45 25 0,000 0,02704663 0,03707931 ! response to starvation GO:0042594 42 25 0,000 0,02704663 0,03705819 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02704663 0,0370371 ! neural crest cell development GO:0014032 54 25 0,000 0,02704663 0,03701603 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02704663 0,03699499 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02704663 0,03697397 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02704663 0,03695297 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02704663 0,036932 ! interaction with host GO:0051701 62 25 0,000 0,02704663 0,03691105 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02704663 0,03689013 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02704663 0,03686923 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02704663 0,03684835 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02704663 0,03682749 ! immunoglobulin production GO:0002377 55 25 0,000 0,02704663 0,03680666 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02704663 0,03678586 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02704663 0,03676507 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02704663 0,03674432 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02704663 0,03672358 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02704663 0,03670287 ! telomere organization GO:0032200 43 25 0,000 0,02704663 0,03668218 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02704663 0,03666151 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02704663 0,03664087 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0281136 0,0380649 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0281136 0,03804349 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0281136 0,03802211 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0281136 0,03800075 ! initiation of viral infection GO:0019059 57 26 0,000 0,0281136 0,03797941 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0281136 0,0379581 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0281136 0,03793681 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0281136 0,03791554 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0281136 0,0378943 ! molting cycle process GO:0022404 50 26 0,000 0,0281136 0,03787308 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0281136 0,03785189 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0281136 0,03783072 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,0281136 0,03780957 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0281136 0,03778845 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0281136 0,03776735 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,0281136 0,03774628 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0281136 0,03772522 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0281136 0,0377042 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0281136 0,03768319 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0281136 0,03766221 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0281136 0,03764125 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0281136 0,03762032 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0281136 0,0375994 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0281136 0,03757852 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0281136 0,03755765 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0281136 0,03753681 ! blastocyst development GO:0001824 49 26 0,000 0,0281136 0,03751599 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0281136 0,03749519 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0281136 0,03747442 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0281136 0,03745367 ! neuron fate commitment GO:0048663 48 27 0,000 0,02917944 0,0388521 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02917944 0,03883061 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02917944 0,03880915 ! iron ion transport GO:0006826 59 27 0,000 0,02917944 0,0387877 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02917944 0,03876629 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02917944 0,03874489 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02917944 0,03872352 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02917944 0,03870217 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02917944 0,03868085 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02917944 0,03865955 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02917944 0,03863827 ! autophagy GO:0006914 41 27 0,000 0,02917944 0,03861702 ! male gonad development GO:0008584 44 27 0,000 0,02917944 0,03859579 ! response to toxin GO:0009636 47 27 0,000 0,02917944 0,03857458 ! primary neural tube formation GO:0014020 51 27 0,000 0,02917944 0,0385534 ! base-excision repair GO:0006284 41 27 0,000 0,02917944 0,03853224 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02917944 0,0385111 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02917944 0,03848999 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02917944 0,0384689 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02917944 0,03844783 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02917944 0,03842679 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02917944 0,03840577 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02917944 0,03838477 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02917944 0,03836379 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03024415 0,03974191 ! circadian rhythm GO:0007623 50 28 0,000 0,03024415 0,03972021 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03024415 0,03969854 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03024415 0,0396769 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03024415 0,03965528 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03024415 0,03963368 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03024415 0,0396121 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03024415 0,03959055 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03024415 0,03956902 ! synaptogenesis GO:0007416 42 28 0,000 0,03024415 0,03954752 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03024415 0,03952604 ! lipid oxidation GO:0034440 43 28 0,000 0,03024415 0,03950458 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03024415 0,03948314 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03024415 0,03946173 ! translational initiation GO:0006413 65 29 0,000 0,03130773 0,04082732 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03130773 0,0408052 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03130773 0,04078311 ! regulation of pH GO:0006885 43 29 0,000 0,03130773 0,04076104 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03130773 0,04073899 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03130773 0,04071697 ! catechol metabolic process GO:0009712 54 29 0,000 0,03130773 0,04069497 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03130773 0,040673 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03130773 0,04065105 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03130773 0,04062912 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03130773 0,04060722 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03130773 0,04058534 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03130773 0,04056349 ! cell fate determination GO:0001709 60 29 0,000 0,03130773 0,04054166 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03130773 0,04051985 ! detection of light stimulus GO:0009583 38 29 0,000 0,03130773 0,04049806 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,03130773 0,0404763 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03130773 0,04045456 ! tissue homeostasis GO:0001894 48 29 0,000 0,03130773 0,04043285 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03130773 0,04041116 ! phenol metabolic process GO:0018958 55 30 0,000 0,03237017 0,04176013 ! zinc ion transport GO:0006829 45 30 0,000 0,03237017 0,04173775 ! membrane docking GO:0022406 61 30 0,000 0,03237017 0,04171539 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03237017 0,04169306 ! cell junction assembly GO:0034329 78 30 0,000 0,03237017 0,04167075 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03237017 0,04164847 ! myofibril assembly GO:0030239 47 30 0,000 0,03237017 0,04162621 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03237017 0,04160397 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03237017 0,04158176 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,03237017 0,04155957 ! phospholipid transport GO:0015914 51 30 0,000 0,03237017 0,04153741 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03237017 0,04151527 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03237017 0,04149315 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03237017 0,04147105 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03237017 0,04144898 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03237017 0,04142694 ! eye morphogenesis GO:0048592 60 30 0,000 0,03237017 0,04140491 ! response to heat GO:0009408 50 30 0,000 0,03237017 0,04138291 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03343149 0,04271703 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03343149 0,04269435 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03343149 0,0426717 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03343149 0,04264908 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,03343149 0,04262648 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03343149 0,0426039 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03343149 0,04258135 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03343149 0,04255882 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,03343149 0,04253631 ! ovulation cycle process GO:0022602 49 31 0,000 0,03343149 0,04251383 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03343149 0,04249137 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03343149 0,04246894 ! peptide transport GO:0015833 55 31 0,000 0,03343149 0,04244652 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03343149 0,04242414 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03343149 0,04240177 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03343149 0,04237943 ! mesoderm formation GO:0001707 69 31 0,000 0,03343149 0,04235712 ! natural killer cell activation GO:0030101 45 31 0,000 0,03343149 0,04233482 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03343149 0,04231255 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,03343149 0,04229031 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03343149 0,04226808 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03343149 0,04224588 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03449168 0,04356271 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03449168 0,04353986 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03449168 0,04351703 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03449168 0,04349422 ! cholesterol transport GO:0030301 56 32 0,000 0,03449168 0,04347144 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03449168 0,04344868 ! spliceosome assembly GO:0000245 67 32 0,000 0,03449168 0,04342594 ! spindle organization GO:0007051 46 32 0,000 0,03449168 0,04340323 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03449168 0,04338054 ! metanephros development GO:0001656 74 32 0,000 0,03449168 0,04335787 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03449168 0,04333523 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03449168 0,04331262 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03449168 0,04329002 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,03449168 0,04326745 ! muscle cell development GO:0055001 49 32 0,000 0,03449168 0,0432449 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03449168 0,04322238 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03449168 0,04319988 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03449168 0,0431774 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03449168 0,04315495 ! ovulation cycle GO:0042698 51 32 0,000 0,03449168 0,04313252 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03449168 0,04311012 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03449168 0,04308773 ! hindbrain development GO:0030902 61 32 0,000 0,03449168 0,04306537 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03449168 0,04304303 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03449168 0,04302072 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,03449168 0,04299843 ! gene silencing GO:0016458 65 32 0,000 0,03449168 0,04297616 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03555073 0,04427281 ! post-embryonic development GO:0009791 69 33 0,000 0,03555073 0,0442499 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03555073 0,04422702 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03555073 0,04420417 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03555073 0,04418134 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03555073 0,04415853 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03555073 0,04413574 ! cell fate specification GO:0001708 52 33 0,000 0,03555073 0,04411298 ! sterol transport GO:0015918 57 33 0,000 0,03555073 0,04409024 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03555073 0,04406753 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03555073 0,04404483 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03555073 0,04402216 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03555073 0,04399952 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03555073 0,0439769 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03660867 0,04526231 ! glial cell differentiation GO:0010001 63 34 0,000 0,03660867 0,04523906 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03660867 0,04521584 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03660867 0,04519264 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03660867 0,04516946 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03660867 0,04514631 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03660867 0,04512318 ! mismatch repair GO:0006298 46 34 0,000 0,03660867 0,04510008 ! spermatid development GO:0007286 63 34 0,000 0,03660867 0,045077 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03660867 0,04505394 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03660867 0,04503091 ! placenta development GO:0001890 53 34 0,000 0,03660867 0,0450079 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03660867 0,04498491 ! regulation of muscle development GO:0048634 70 35 0,000 0,03766547 0,04625989 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03766547 0,04623629 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03766547 0,04621271 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03766547 0,04618916 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03766547 0,04616563 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03766547 0,04614212 ! odontogenesis GO:0042476 66 35 0,000 0,03766547 0,04611864 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03766547 0,04609518 ! female gonad development GO:0008585 58 35 0,000 0,03766547 0,04607175 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03766547 0,04604834 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03766547 0,04602495 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03766547 0,04600159 ! cytokine production GO:0001816 59 35 0,000 0,03766547 0,04597825 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,03766547 0,04595493 ! neural tube formation GO:0001841 67 35 0,000 0,03766547 0,04593164 ! vesicle localization GO:0051648 64 35 0,000 0,03766547 0,04590837 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03872116 0,04717119 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03872116 0,04714732 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03872116 0,04712347 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03872116 0,04709965 ! cell junction organization GO:0034330 86 36 0,000 0,03872116 0,04707585 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03872116 0,04705207 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03872116 0,04702832 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03872116 0,04700459 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03872116 0,04698089 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03872116 0,04695721 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03872116 0,04693355 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03872116 0,04690992 ! aerobic respiration GO:0009060 55 36 0,000 0,03872116 0,04688631 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03872116 0,04686273 ! embryonic organ development GO:0048568 57 36 0,000 0,03872116 0,04683917 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03872116 0,04681563 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03872116 0,04679211 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03977571 0,04804235 ! meiosis I GO:0007127 65 37 0,000 0,03977571 0,04801825 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03977571 0,04799417 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03977571 0,04797011 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03977571 0,04794608 ! organic anion transport GO:0015711 68 37 0,000 0,03977571 0,04792207 ! tissue remodeling GO:0048771 76 37 0,000 0,03977571 0,04789808 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03977571 0,04787412 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03977571 0,04785018 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03977571 0,04782627 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03977571 0,04780238 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03977571 0,04777852 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03977571 0,04775468 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03977571 0,04773086 ! pigment metabolic process GO:0042440 80 37 0,000 0,03977571 0,04770706 ! spermatid differentiation GO:0048515 66 37 0,000 0,03977571 0,04768329 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03977571 0,04765955 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04082915 0,04889743 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04082915 0,0488731 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04082915 0,0488488 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04082915 0,04882452 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04082915 0,04880027 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04082915 0,04877604 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04082915 0,04875183 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04082915 0,04872765 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04082915 0,04870349 ! lipid homeostasis GO:0055088 67 38 0,000 0,04082915 0,04867936 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04082915 0,04865525 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04082915 0,04863116 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04082915 0,0486071 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04082915 0,04858306 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04082915 0,04855904 ! glucan metabolic process GO:0044042 62 38 0,000 0,04082915 0,04853505 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,04188147 0,04976139 ! mammary gland development GO:0030879 86 39 0,000 0,04188147 0,04973683 ! learning GO:0007612 77 39 0,000 0,04188147 0,04971229 ! ear morphogenesis GO:0042471 60 39 0,000 0,04188147 0,04968778 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04188147 0,04966329 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04188147 0,04963882 ! segmentation GO:0035282 67 39 0,000 0,04188147 0,04961438 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04188147 0,04958997 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04188147 0,04956558 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04188147 0,04954121 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04188147 0,04951686 ! RNA modification GO:0009451 57 39 0,000 0,04188147 0,04949254 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04293267 0,05070986 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04293267 0,05068498 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04293267 0,05066013 ! feeding behavior GO:0007631 59 40 0,000 0,04293267 0,05063529 ! negative regulation of binding GO:0051100 72 40 0,000 0,04293267 0,05061048 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,04293267 0,0505857 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04293267 0,05056094 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04293267 0,0505362 ! maintenance of protein location GO:0045185 91 40 0,000 0,04293267 0,05051149 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04398275 0,05172164 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04398275 0,05169638 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04398275 0,05167114 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04398275 0,05164592 ! gliogenesis GO:0042063 88 41 0,000 0,04398275 0,05162072 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04398275 0,05159556 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04398275 0,05157041 ! T cell differentiation GO:0030217 81 41 0,000 0,04398275 0,05154529 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,04398275 0,0515202 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04398275 0,05149513 ! female gamete generation GO:0007292 61 41 0,000 0,04398275 0,05147008 ! polyol metabolic process GO:0019751 66 41 0,000 0,04398275 0,05144506 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04398275 0,05142006 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,04503171 0,05262083 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,04503171 0,05259528 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,04503171 0,05256977 ! regulation of tube size GO:0035150 71 42 0,000 0,04503171 0,05254427 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,04503171 0,0525188 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,04503171 0,05249336 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,04503171 0,05246794 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,04503171 0,05244254 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,04503171 0,05241717 ! neuron migration GO:0001764 79 42 0,000 0,04503171 0,05239182 ! regulation of protein secretion GO:0050708 71 42 0,000 0,04503171 0,0523665 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,04503171 0,0523412 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,04607955 0,05353327 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04607955 0,05350743 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04607955 0,05348162 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04607955 0,05345584 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,04607955 0,05343007 ! glucose transport GO:0015758 65 43 0,000 0,04607955 0,05340434 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,04607955 0,05337862 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04607955 0,05335294 ! neural tube development GO:0021915 77 43 0,000 0,04607955 0,05332727 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04607955 0,05330164 ! striated muscle contraction GO:0006941 77 43 0,000 0,04607955 0,05327602 ! phagocytosis GO:0006909 90 43 0,000 0,04607955 0,05325043 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04607955 0,05322487 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04712628 0,05440779 ! hexose transport GO:0008645 67 44 0,000 0,04712628 0,0543817 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04712628 0,05435563 ! male sex differentiation GO:0046661 76 44 0,000 0,04712628 0,05432958 ! double-strand break repair GO:0006302 81 44 0,000 0,04712628 0,05430356 ! biopolymer methylation GO:0043414 84 44 0,000 0,04712628 0,05427757 ! B cell differentiation GO:0030183 107 44 0,000 0,04712628 0,0542516 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04712628 0,05422565 ! developmental growth GO:0048589 82 44 0,000 0,04712628 0,05419973 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04712628 0,05417383 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,0481719 0,05534937 ! glycolysis GO:0006096 65 45 0,000 0,0481719 0,05532295 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,0481719 0,05529656 ! leukocyte migration GO:0050900 68 45 0,000 0,0481719 0,05527019 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,0481719 0,05524385 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,0481719 0,05521753 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,0481719 0,05519123 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,0481719 0,05516496 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,0481719 0,05513872 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,0481719 0,0551125 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,0481719 0,05508631 ! cell growth GO:0016049 84 45 0,000 0,0481719 0,05506014 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0492164 0,05622729 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0492164 0,0562006 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0492164 0,05617394 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0492164 0,05614731 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0492164 0,0561207 ! pigmentation GO:0043473 100 46 0,000 0,0492164 0,05609411 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0492164 0,05606755 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0502598 0,05722909 ! endosome transport GO:0016197 108 47 0,000 0,0502598 0,05720202 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0502598 0,05717497 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0502598 0,05714795 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0502598 0,05712096 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0502598 0,05709399 ! JNK cascade GO:0007254 91 47 0,000 0,0502598 0,05706705 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0502598 0,05704013 ! methylation GO:0032259 90 47 0,000 0,0502598 0,05701323 ! protein homooligomerization GO:0051260 76 47 0,000 0,0502598 0,05698637 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05130208 0,05814074 ! cellular component disassembly GO:0022411 86 48 0,000 0,05130208 0,05811337 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05130208 0,05808602 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,05130208 0,0580587 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,05130208 0,05803141 ! activation of caspase activity GO:0006919 84 48 0,000 0,05130208 0,05800414 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05130208 0,05797689 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05130208 0,05794967 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05130208 0,05792248 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,05234325 0,05907029 ! regulation of action potential GO:0001508 95 49 0,000 0,05234325 0,0590426 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,05234325 0,05901493 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,05234325 0,05898729 ! regulation of ion transport GO:0043269 77 49 0,000 0,05234325 0,05895967 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,05234325 0,05893208 ! peptide metabolic process GO:0006518 76 49 0,000 0,05234325 0,05890452 ! response to temperature stimulus GO:0009266 76 49 0,000 0,05234325 0,05887698 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,05234325 0,05884947 ! endocrine system development GO:0035270 104 49 0,000 0,05234325 0,05882198 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,05234325 0,05879452 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,05234325 0,05876708 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,05338332 0,05990684 ! neuromuscular process GO:0050905 99 50 0,000 0,05338332 0,05987891 ! regulation of ossification GO:0030278 117 50 0,000 0,05338332 0,05985101 ! inner ear development GO:0048839 79 50 0,000 0,05338332 0,05982313 ! histone modification GO:0016570 91 50 0,000 0,05338332 0,05979528 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05338332 0,05976745 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05338332 0,05973966 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05338332 0,05971188 ! positive regulation of binding GO:0051099 78 51 0,000 0,05442227 0,06084572 ! viral infectious cycle GO:0019058 99 51 0,000 0,05442227 0,06081746 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,05442227 0,06078923 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,05442227 0,06076102 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,05442227 0,06073283 ! excretion GO:0007588 83 51 0,000 0,05442227 0,06070468 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,05442227 0,06067655 ! chromatin remodeling GO:0006338 109 51 0,000 0,05442227 0,06064844 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,05442227 0,06062037 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,05442227 0,06059231 ! vesicle organization GO:0016050 107 51 0,000 0,05442227 0,06056429 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,05442227 0,06053629 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,05546013 0,06166223 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,05546013 0,06163375 ! membrane fusion GO:0006944 110 52 0,000 0,05546013 0,06160529 ! positive regulation of growth GO:0045927 90 52 0,000 0,05546013 0,06157686 ! covalent chromatin modification GO:0016569 101 52 0,000 0,05546013 0,06154846 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,05546013 0,06152009 ! amino acid activation GO:0043038 92 52 0,000 0,05546013 0,06149173 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,05546013 0,06146341 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,05649687 0,06258355 ! RNA catabolic process GO:0006401 93 53 0,000 0,05649687 0,06255475 ! regulation of translational initiation GO:0006446 82 53 0,000 0,05649687 0,06252598 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,05649687 0,06249723 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,05649687 0,06246851 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,05649687 0,06243982 ! cell maturation GO:0048469 100 53 0,000 0,05649687 0,06241115 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,05649687 0,06238251 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,05649687 0,06235389 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05753252 0,06346778 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,05753252 0,0634387 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05753252 0,06340964 ! cell recognition GO:0008037 85 54 0,000 0,05753252 0,0633806 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05753252 0,0633516 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05753252 0,06332262 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05753252 0,06329366 ! chloride transport GO:0006821 90 55 0,000 0,05856706 0,06440235 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,05856706 0,06437293 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,05856706 0,06434354 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,05856706 0,06431417 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,05856706 0,06428483 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,05856706 0,06425552 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,05856706 0,06422623 ! aging GO:0007568 103 55 0,000 0,05856706 0,06419697 ! gastrulation GO:0007369 112 55 0,000 0,05856706 0,06416774 ! heart morphogenesis GO:0003007 97 55 0,000 0,05856706 0,06413853 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,05856706 0,06410935 ! RNA elongation GO:0006354 79 55 0,000 0,05856706 0,06408019 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,05856706 0,06405107 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0596005 0,06515166 ! sensory perception of smell GO:0007608 80 56 0,000 0,0596005 0,06512207 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0596005 0,06509251 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0596005 0,06506298 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0596005 0,06503347 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0596005 0,06500399 ! proton transport GO:0015992 94 56 0,000 0,0596005 0,06497454 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06063284 0,06607002 ! muscle fiber development GO:0048747 112 57 0,000 0,06063284 0,06604012 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06063284 0,06601023 ! lipid modification GO:0030258 97 57 0,000 0,06063284 0,06598038 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06063284 0,06595055 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,06063284 0,06592075 ! maintenance of location GO:0051235 118 57 0,000 0,06063284 0,06589097 ! hydrogen transport GO:0006818 97 58 0,000 0,06166408 0,06698139 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,06166408 0,06695117 ! regulation of endocytosis GO:0030100 91 58 0,000 0,06166408 0,06692097 ! adult behavior GO:0030534 99 58 0,000 0,06166408 0,06689079 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,06166408 0,06686065 ! positive regulation of secretion GO:0051047 95 59 0,000 0,06269423 0,06794699 ! regulation of cellular component size GO:0032535 109 59 0,000 0,06269423 0,06791639 ! DNA catabolic process GO:0006308 86 59 0,000 0,06269423 0,06788583 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,06269423 0,06785529 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,06372327 0,06893804 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,06372327 0,06890705 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,06372327 0,0688761 ! regulation of heart contraction GO:0008016 110 60 0,000 0,06372327 0,06884517 ! camera-type eye development GO:0043010 116 60 0,000 0,06372327 0,06881427 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,06372327 0,0687834 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,06372327 0,06875255 ! kidney development GO:0001822 122 60 0,000 0,06372327 0,06872174 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,06475122 0,06979903 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,06475122 0,06976778 ! mesoderm development GO:0007498 119 61 0,000 0,06475122 0,06973655 ! tRNA processing GO:0008033 89 61 0,000 0,06475122 0,06970534 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,06475122 0,06967417 ! ear development GO:0043583 103 62 0,000 0,06577808 0,07074746 ! viral reproductive process GO:0022415 126 62 0,000 0,06577808 0,07071585 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,06577808 0,07068426 ! gonad development GO:0008406 98 62 0,000 0,06577808 0,07065271 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,06577808 0,07062118 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,06680384 0,07169048 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,06680384 0,07165852 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,06680384 0,07162658 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,06680384 0,07159468 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,06782852 0,07266047 ! cell redox homeostasis GO:0045454 102 64 0,000 0,06782852 0,07262813 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,06782852 0,07259582 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,06782852 0,07256354 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,06782852 0,07253129 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,06782852 0,07249907 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0688521 0,07356045 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0688521 0,0735278 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0688521 0,07349518 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0688521 0,07346259 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0688521 0,07343003 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,06987459 0,07448749 ! actin filament organization GO:0007015 148 66 0,000 0,06987459 0,0744545 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,06987459 0,07442154 ! extracellular matrix organization GO:0030198 133 66 0,000 0,06987459 0,07438861 ! secondary metabolic process GO:0019748 116 66 0,000 0,06987459 0,07435571 ! developmental maturation GO:0021700 116 66 0,000 0,06987459 0,07432284 ! cell projection assembly GO:0030031 120 66 0,000 0,06987459 0,07428999 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,07089599 0,07534264 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,07089599 0,07530938 ! activation of MAPK activity GO:0000187 115 67 0,000 0,07089599 0,07527615 ! lung development GO:0030324 144 67 0,000 0,07089599 0,07524294 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,07089599 0,07520976 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,07089599 0,07517662 ! hexose catabolic process GO:0019320 104 67 0,000 0,07089599 0,0751435 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,07089599 0,07511041 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,07089599 0,07507735 ! adaptive immune response GO:0002250 119 67 0,000 0,07089599 0,07504432 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,07089599 0,07501132 ! amino acid transport GO:0006865 125 68 0,000 0,0719163 0,07605742 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,0719163 0,076024 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,0719163 0,07599061 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,0719163 0,07595725 ! viral reproduction GO:0016032 134 68 0,000 0,0719163 0,07592392 ! regulation of lipase activity GO:0060191 130 68 0,000 0,0719163 0,07589062 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,0719163 0,07585735 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,07293553 0,07689872 ! urogenital system development GO:0001655 137 69 0,000 0,07293553 0,07686504 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,07293553 0,07683138 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,07293553 0,07679776 ! antigen processing and presentation GO:0019882 104 69 0,000 0,07293553 0,07676417 ! appendage morphogenesis GO:0035107 135 70 0,000 0,07395367 0,07780172 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,07395367 0,07776772 ! amine catabolic process GO:0009310 117 71 0,000 0,07497073 0,07880278 ! reproductive structure development GO:0048608 113 71 0,000 0,07497073 0,07876837 ! appendage development GO:0048736 136 71 0,000 0,07497073 0,07873399 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,07497073 0,07869964 ! B cell activation GO:0042113 160 71 0,000 0,07497073 0,07866532 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,07497073 0,07863103 ! regulation of immune effector process GO:0002697 137 71 0,000 0,07497073 0,07859676 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0759867 0,07962718 ! carbohydrate transport GO:0008643 110 72 0,000 0,0759867 0,07959252 ! respiratory system development GO:0060541 153 72 0,000 0,0759867 0,07955788 ! learning or memory GO:0007611 147 73 0,000 0,0770016 0,0805854 ! regulation of blood pressure GO:0008217 125 73 0,000 0,0770016 0,08055036 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,0770016 0,08051536 ! axon guidance GO:0007411 139 73 0,000 0,0770016 0,08048038 ! fertilization GO:0009566 90 73 0,000 0,0770016 0,08044544 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,07801541 0,08146921 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,07801541 0,08143387 ! neurotransmitter transport GO:0006836 123 74 0,000 0,07801541 0,08139856 ! meiosis GO:0007126 121 74 0,000 0,07801541 0,08136327 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,07801541 0,08132802 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,07801541 0,0812928 ! eye development GO:0001654 143 74 0,000 0,07801541 0,08125761 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,07902814 0,08227681 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,07902814 0,08224122 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,07902814 0,08220566 ! meiotic cell cycle GO:0051321 122 75 0,000 0,07902814 0,08217014 ! rhythmic process GO:0048511 128 75 0,000 0,07902814 0,08213464 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,07902814 0,08209918 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,08003979 0,08311426 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,08003979 0,0830784 ! defense response to bacterium GO:0042742 89 76 0,000 0,08003979 0,08304258 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,08003979 0,08300678 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,08003979 0,08297102 ! regulation of catabolic process GO:0009894 161 76 0,000 0,08003979 0,08293529 ! blood coagulation GO:0007596 146 78 0,000 0,08205986 0,08499184 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,08205986 0,08495526 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,08205986 0,08491872 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,08205986 0,08488222 ! protein oligomerization GO:0051259 139 78 0,000 0,08205986 0,08484574 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,08306829 0,0858515 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,08306829 0,08581464 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,08306829 0,08577781 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,08306829 0,08574101 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,08407564 0,08674356 ! muscle cell differentiation GO:0042692 159 80 0,000 0,08407564 0,08670638 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,08407564 0,08666923 ! protein import into nucleus GO:0006606 158 80 0,000 0,08407564 0,08663211 ! inorganic anion transport GO:0015698 138 80 0,000 0,08407564 0,08659503 ! T cell activation GO:0042110 168 81 0,000 0,08508191 0,08759396 ! response to hypoxia GO:0001666 171 81 0,000 0,08508191 0,08755649 ! digestion GO:0007586 112 81 0,000 0,08508191 0,08751906 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,08508191 0,08748166 ! nuclear import GO:0051170 161 81 0,000 0,08508191 0,08744429 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,08508191 0,08740695 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,08608712 0,08840188 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,08608712 0,08836416 ! response to nutrient GO:0007584 125 82 0,000 0,08608712 0,08832648 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,08608712 0,08828883 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,08608712 0,08825121 ! response to oxygen levels GO:0070482 176 83 0,000 0,08709125 0,08924257 ! regulation of lyase activity GO:0051339 160 83 0,000 0,08709125 0,08920457 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,08809431 0,09019358 ! hemostasis GO:0007599 158 84 0,000 0,08809431 0,09015522 ! negative regulation of transport GO:0051051 153 84 0,000 0,08809431 0,09011688 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,08809431 0,09007859 ! nucleosome assembly GO:0006334 122 85 0,000 0,08909631 0,09106445 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,08909631 0,09102578 ! amine biosynthetic process GO:0009309 138 86 0,000 0,09009723 0,09200931 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,09009723 0,09197028 ! chromatin assembly GO:0031497 124 86 0,000 0,09009723 0,09193127 ! tube morphogenesis GO:0035239 176 86 0,000 0,09009723 0,0918923 ! alcohol catabolic process GO:0046164 130 86 0,000 0,09009723 0,09185336 ! amine transport GO:0015837 155 86 0,000 0,09009723 0,09181446 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,09109709 0,09279407 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,09109709 0,0927548 ! protein localization in nucleus GO:0034504 176 87 0,000 0,09109709 0,09271557 ! regulation of protein transport GO:0051223 154 87 0,000 0,09109709 0,09267636 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,09209589 0,09365287 ! regulation of DNA binding GO:0051101 155 88 0,000 0,09209589 0,09361331 ! gland development GO:0048732 206 88 0,000 0,09209589 0,09357378 ! regulation of neurological system process GO:0031644 148 88 0,000 0,09209589 0,09353428 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,09209589 0,09349481 ! cellular defense response GO:0006968 114 89 0,000 0,09309362 0,09446784 ! ossification GO:0001503 188 90 0,000 0,09409028 0,09543896 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,09409028 0,09539874 ! sex differentiation GO:0007548 145 90 0,000 0,09409028 0,09535856 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,09409028 0,09531841 ! bone development GO:0060348 189 91 0,000 0,09508589 0,09628647 ! sterol metabolic process GO:0016125 152 91 0,000 0,09508589 0,09624596 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,09508589 0,09620549 ! regulation of defense response GO:0031347 149 92 0,000 0,09608043 0,09717088 ! nucleosome organization GO:0034728 138 92 0,000 0,09608043 0,09713005 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,09608043 0,09708926 ! vitamin metabolic process GO:0006766 139 92 0,000 0,09608043 0,0970485 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,09707391 0,09801084 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,09707391 0,09796973 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,09707391 0,09792865 ! regulation of membrane potential GO:0042391 164 93 0,000 0,09707391 0,09788761 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,09707391 0,0978466 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,09806634 0,09880553 ! female pregnancy GO:0007565 164 94 0,000 0,09806634 0,09876417 ! transcription initiation GO:0006352 153 94 0,000 0,09806634 0,09872285 ! regulation of T cell activation GO:0050863 158 94 0,000 0,09806634 0,09868156 ! forebrain development GO:0030900 188 95 0,000 0,09905771 0,09963748 ! leukocyte differentiation GO:0002521 202 96 0,000 0,10004802 0,10059153 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,10004802 0,10054951 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,10004802 0,10050753 ! positive regulation of immune response GO:0050778 156 96 0,000 0,10004802 0,10046558 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,10103727 0,10141664 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,10103727 0,10137434 ! protein ubiquitination GO:0016567 217 97 0,000 0,10103727 0,10133209 ! hormone metabolic process GO:0042445 157 97 0,000 0,10103727 0,10128986 ! regulation of protein localization GO:0032880 176 97 0,000 0,10103727 0,10124768 ! response to virus GO:0009615 160 98 0,000 0,10202547 0,10219537 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,10202547 0,10215284 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,10202547 0,10211035 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,10301262 0,10305545 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,10301262 0,10301262 GO:0060538|skeletal muscle organ development,