pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/55257-6-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 6,000 2,074E-13 4,99E-10 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 6,000 2,827E-13 3,401E-10 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 6,000 2,827E-13 2,267E-10 ! positive regulation of ligase activity GO:0051351 124 77 6,000 4,601E-13 2,768E-10 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 6,000 5,54E-13 2,666E-10 ! regulation of ligase activity GO:0051340 142 84 6,000 8,631E-13 3,461E-10 ! spindle assembly GO:0051225 6 5 3,000 2,559E-12 8,795E-10 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 5,000 3,014E-11 9,064E-09 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 1,071E-10 2,864E-08 GO:0042267|natural killer cell mediated cytotoxicity, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 5,000 2,068E-10 4,975E-08 GO:0010498|proteasomal protein catabolic process, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 2,522E-10 5,517E-08 ! cell killing GO:0001906 29 15 3,000 6,943E-10 1,392E-07 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 3,637E-09 6,732E-07 ! negative regulation of ligase activity GO:0051352 112 68 4,000 3,923E-09 6,743E-07 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! spindle organization GO:0007051 46 32 3,000 1,81E-08 2,903E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,958E-07 2,945E-05 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 3,136E-07 4,439E-05 ! leukocyte mediated immunity GO:0002443 128 74 3,000 5,645E-07 7,546E-05 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 7,727E-06 9,785E-04 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 7,727E-06 9,295E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 9,506E-06 1,089E-03 ! response to UV GO:0009411 104 53 2,000 1,461E-05 1,598E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,16E-05 2,259E-03 ! DNA topological change GO:0006265 12 8 1,000 2,16E-05 2,165E-03 ! mast cell activation GO:0045576 14 8 1,000 2,16E-05 2,079E-03 ! phosphate transport GO:0006817 19 9 1,000 2,776E-05 2,568E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,468E-05 3,09E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,468E-05 2,98E-03 ! DNA ligation GO:0006266 19 10 1,000 3,468E-05 2,877E-03 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 3,468E-05 2,781E-03 ! response to metal ion GO:0010038 140 80 2,000 5,042E-05 3,913E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,08E-05 3,82E-03 ! response to inorganic substance GO:0010035 153 86 2,000 6,257E-05 4,562E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 8,418E-05 5,957E-03 ! interphase GO:0051325 213 98 2,000 9,233E-05 6,347E-03 ! regulation of viral genome replication GO:0045069 28 17 1,000 1,044E-04 6,977E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,311E-04 8,526E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,768E-04 0,01119556 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,768E-04 0,01090849 ! vesicle targeting GO:0006903 43 23 1,000 1,936E-04 0,01164227 ! regulation of viral reproduction GO:0050792 38 23 1,000 1,936E-04 0,01135831 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,11E-04 0,01208918 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,11E-04 0,01180803 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,293E-04 0,01253618 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,293E-04 0,0122576 ! chromosome condensation GO:0030261 45 25 1,000 2,293E-04 0,01199113 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,482E-04 0,01270697 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,679E-04 0,0134302 ! fat cell differentiation GO:0045444 50 27 1,000 2,679E-04 0,01315611 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,884E-04 0,01387708 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,096E-04 0,01460468 ! regulation of B cell activation GO:0050864 50 30 1,000 3,315E-04 0,01533847 ! myeloid leukocyte activation GO:0002274 49 31 1,000 3,542E-04 0,01607804 ! establishment of vesicle localization GO:0051650 61 33 1,000 4,017E-04 0,01789847 ! vesicle localization GO:0051648 64 35 1,000 4,522E-04 0,01978107 ! nucleus organization GO:0006997 67 38 1,000 5,334E-04 0,0229162 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,334E-04 0,02251416 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 7,482E-04 0,03103863 ! response to calcium ion GO:0051592 81 47 1,000 8,161E-04 0,03328045 ! positive regulation of cell cycle GO:0045787 89 48 1,000 8,511E-04 0,03412977 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 8,511E-04 0,03357027 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 9,604E-04 0,03727128 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein catabolic process GO:0042176 116 55 1,000 1,116E-03 0,04262674 ! establishment of organelle localization GO:0051656 109 59 1,000 1,283E-03 0,04823996 ! regulation of mitosis GO:0007088 105 63 1,000 1,461E-03 0,05409619 GO:0051783|regulation of nuclear division, ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 1,651E-03 0,06018158 ! negative regulation of cell growth GO:0030308 132 67 1,000 1,651E-03 0,05928335 ! chromosome segregation GO:0007059 113 67 1,000 1,651E-03 0,05841153 ! negative regulation of kinase activity GO:0033673 131 68 1,000 1,7E-03 0,05927665 ! negative regulation of cell size GO:0045792 134 69 1,000 1,75E-03 0,06014081 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,903E-03 0,06449451 ! negative regulation of transferase activity GO:0051348 140 72 1,000 1,903E-03 0,06359876 ! organelle localization GO:0051640 136 74 1,000 2,009E-03 0,06621291 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 2,063E-03 0,06707066 ! steroid biosynthetic process GO:0006694 131 76 1,000 2,117E-03 0,06792744 ! regulation of catabolic process GO:0009894 161 76 1,000 2,117E-03 0,06703366 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 2,173E-03 0,06788998 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 2,285E-03 0,07049202 ! inorganic anion transport GO:0015698 138 80 1,000 2,343E-03 0,07134495 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,401E-03 0,07219693 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 2,579E-03 0,0765927 ! response to unfolded protein GO:0006986 131 85 1,000 2,639E-03 0,07743902 ! positive regulation of cell activation GO:0050867 145 85 1,000 2,639E-03 0,07650602 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,825E-03 0,08092442 ! regulation of cell cycle process GO:0010564 149 90 1,000 2,953E-03 0,08357792 ! response to protein stimulus GO:0051789 149 91 1,000 3,017E-03 0,08441584 ! cell cycle arrest GO:0007050 213 100 1,000 3,629E-03 0,10036903 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 4,475E-03 0,12234469 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,475E-03 0,12097003 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,475E-03 0,11962591 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,475E-03 0,11831134 ! neuron fate determination GO:0048664 7 5 0,000 4,475E-03 0,11702535 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,475E-03 0,11576701 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,475E-03 0,11453545 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,475E-03 0,11332981 ! polyol transport GO:0015791 12 5 0,000 4,475E-03 0,11214929 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,475E-03 0,11099312 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,475E-03 0,10986053 ! response to superoxide GO:0000303 10 5 0,000 4,475E-03 0,10875083 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,475E-03 0,10766332 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,475E-03 0,10659735 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,475E-03 0,10555228 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,475E-03 0,1045275 ! female meiosis GO:0007143 7 5 0,000 4,475E-03 0,10352243 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,475E-03 0,1025365 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,475E-03 0,10156917 ! cobalt ion transport GO:0006824 11 5 0,000 4,475E-03 0,10061993 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,475E-03 0,09968826 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,475E-03 0,09877369 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,475E-03 0,09787575 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,475E-03 0,09699398 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,475E-03 0,09612797 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,475E-03 0,09527728 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,475E-03 0,09444151 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,475E-03 0,09362028 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,475E-03 0,09281321 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,475E-03 0,09201993 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,475E-03 0,0912401 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,475E-03 0,09047338 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,475E-03 0,08971944 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,475E-03 0,08897795 ! negative chemotaxis GO:0050919 14 5 0,000 4,475E-03 0,08824863 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,475E-03 0,08753116 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,475E-03 0,08682526 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,475E-03 0,08613066 ! behavioral response to pain GO:0048266 9 5 0,000 4,475E-03 0,08544708 ! clathrin coat assembly GO:0048268 14 5 0,000 4,475E-03 0,08477427 ! Notch receptor processing GO:0007220 8 5 0,000 4,475E-03 0,08411197 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,475E-03 0,08345994 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,475E-03 0,08281794 ! micturition GO:0060073 9 5 0,000 4,475E-03 0,08218574 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,475E-03 0,08156312 ! copulation GO:0007620 9 5 0,000 4,475E-03 0,08094987 ! glial cell fate commitment GO:0021781 13 5 0,000 4,475E-03 0,08034576 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,475E-03 0,07975061 ! spermidine metabolic process GO:0008216 7 5 0,000 4,475E-03 0,07916421 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,475E-03 0,07858637 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,475E-03 0,0780169 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,475E-03 0,07745563 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,475E-03 0,07690237 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,475E-03 0,07635697 ! grooming behavior GO:0007625 6 5 0,000 4,475E-03 0,07581924 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,475E-03 0,07528904 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,475E-03 0,0747662 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,475E-03 0,07425057 ! response to protozoan GO:0001562 10 5 0,000 4,475E-03 0,073742 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,475E-03 0,07324036 ! lymph vessel development GO:0001945 10 5 0,000 4,475E-03 0,07274549 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,475E-03 0,07225726 ! endochondral ossification GO:0001958 16 5 0,000 4,475E-03 0,07177555 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,475E-03 0,07130021 ! parathyroid gland development GO:0060017 13 5 0,000 4,475E-03 0,07083113 ! anagen GO:0042640 6 5 0,000 4,475E-03 0,07036818 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,475E-03 0,06991125 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,475E-03 0,06946021 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,475E-03 0,06901495 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,475E-03 0,06857536 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,475E-03 0,06814134 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,475E-03 0,06771278 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,475E-03 0,06728958 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,475E-03 0,06687163 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,475E-03 0,06645884 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,475E-03 0,06605112 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,475E-03 0,06564837 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,475E-03 0,0652505 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,475E-03 0,06485742 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,475E-03 0,06446906 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,475E-03 0,06408531 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,475E-03 0,06370611 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,475E-03 0,06333137 ! histidine catabolic process GO:0006548 6 5 0,000 4,475E-03 0,06296101 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,475E-03 0,06259496 ! microvillus organization GO:0032528 7 5 0,000 4,475E-03 0,06223313 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,475E-03 0,06187547 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,475E-03 0,0615219 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,475E-03 0,06117234 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,475E-03 0,06082674 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,475E-03 0,06048501 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,475E-03 0,06014711 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,475E-03 0,05981296 ! polyol catabolic process GO:0046174 7 5 0,000 4,475E-03 0,0594825 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,475E-03 0,05915567 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,475E-03 0,05883242 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,475E-03 0,05851268 ! muscle cell migration GO:0014812 8 5 0,000 4,475E-03 0,05819639 ! mitochondrial fission GO:0000266 8 5 0,000 4,475E-03 0,05788351 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,475E-03 0,05757397 ! mRNA transcription GO:0009299 9 5 0,000 4,475E-03 0,05726773 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,475E-03 0,05696472 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,475E-03 0,05666491 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,475E-03 0,05636823 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,475E-03 0,05607465 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,475E-03 0,05578411 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,475E-03 0,05549656 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,475E-03 0,05521196 ! response to food GO:0032094 6 5 0,000 4,475E-03 0,05493027 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,475E-03 0,05465143 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,475E-03 0,05437542 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,475E-03 0,05410217 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,475E-03 0,05383166 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,475E-03 0,05356384 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,475E-03 0,05329867 ! forebrain neuron development GO:0021884 13 5 0,000 4,475E-03 0,05303612 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,475E-03 0,05277614 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,475E-03 0,05251869 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,475E-03 0,05226375 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,475E-03 0,05201127 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,475E-03 0,05176121 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,475E-03 0,05151355 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,475E-03 0,05126825 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,475E-03 0,05102527 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,475E-03 0,05078459 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,475E-03 0,05054616 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,475E-03 0,05030996 ! basic amino acid transport GO:0015802 11 5 0,000 4,475E-03 0,05007596 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,475E-03 0,04984413 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,475E-03 0,04961443 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,475E-03 0,04938685 ! depyrimidination GO:0045008 10 5 0,000 4,475E-03 0,04916133 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,475E-03 0,04893787 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,475E-03 0,04871644 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,475E-03 0,04849699 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,475E-03 0,04827952 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,475E-03 0,04806398 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,475E-03 0,04785037 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,475E-03 0,04763864 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,475E-03 0,04742878 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,475E-03 0,04722076 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,475E-03 0,04701455 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,475E-03 0,04681014 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,475E-03 0,0466075 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,475E-03 0,0464066 ! response to arsenic GO:0046685 10 5 0,000 4,475E-03 0,04620743 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,475E-03 0,04600997 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,475E-03 0,04581418 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,475E-03 0,04562005 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,475E-03 0,04542756 ! response to cadmium ion GO:0046686 7 5 0,000 4,475E-03 0,04523669 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,475E-03 0,04504742 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,475E-03 0,04485972 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,475E-03 0,04467358 ! decidualization GO:0046697 11 5 0,000 4,475E-03 0,04448898 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,475E-03 0,04430589 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,475E-03 0,04412431 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,475E-03 0,04394421 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,475E-03 0,04376558 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,475E-03 0,04358839 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,475E-03 0,04341263 ! neural tube patterning GO:0021532 7 5 0,000 4,475E-03 0,04323828 ! embryonic cleavage GO:0040016 6 5 0,000 4,475E-03 0,04306533 ! peroxisome fission GO:0016559 5 5 0,000 4,475E-03 0,04289375 ! histone demethylation GO:0016577 10 5 0,000 4,475E-03 0,04272354 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,475E-03 0,04255467 ! mitotic recombination GO:0006312 9 5 0,000 4,475E-03 0,04238714 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,475E-03 0,04222091 ! metaphase plate congression GO:0051310 7 5 0,000 4,475E-03 0,04205599 ! regulation of sterol transport GO:0032371 7 5 0,000 4,475E-03 0,04189234 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,475E-03 0,04172997 ! enteric nervous system development GO:0048484 8 5 0,000 4,475E-03 0,04156885 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,475E-03 0,04140897 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,475E-03 0,04125032 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,475E-03 0,04109287 ! muscle cell proliferation GO:0033002 11 5 0,000 4,475E-03 0,04093662 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,475E-03 0,04078156 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,475E-03 0,04062767 ! plasminogen activation GO:0031639 5 5 0,000 4,475E-03 0,04047493 ! B cell homeostasis GO:0001782 13 5 0,000 4,475E-03 0,04032334 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,475E-03 0,04017288 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,475E-03 0,04002354 ! metaphase GO:0051323 8 5 0,000 4,475E-03 0,0398753 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,475E-03 0,03972816 ! cellular response to nutrient GO:0031670 8 5 0,000 4,475E-03 0,0395821 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,475E-03 0,03943711 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,475E-03 0,03929318 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,475E-03 0,0391503 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,475E-03 0,03900845 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,475E-03 0,03886763 ! response to redox state GO:0051775 5 5 0,000 4,475E-03 0,03872781 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,475E-03 0,038589 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,475E-03 0,03845119 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,475E-03 0,03831435 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,475E-03 0,03817848 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,475E-03 0,03804358 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,475E-03 0,03790962 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,475E-03 0,0377766 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,475E-03 0,03764452 ! striatum development GO:0021756 9 5 0,000 4,475E-03 0,03751335 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,475E-03 0,0373831 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 4,475E-03 0,03725374 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,475E-03 0,03712528 ! glial cell migration GO:0008347 11 5 0,000 4,475E-03 0,03699771 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,475E-03 0,036871 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,475E-03 0,03674516 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,475E-03 0,03662018 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,475E-03 0,03649604 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,475E-03 0,03637274 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,475E-03 0,03625028 ! neuroprotection GO:0043526 6 5 0,000 4,475E-03 0,03612863 ! neural plate development GO:0001840 8 5 0,000 4,475E-03 0,0360078 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,475E-03 0,03588777 ! regulation of sensory perception GO:0051931 7 5 0,000 4,475E-03 0,03576855 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,475E-03 0,03565011 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,475E-03 0,03553245 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,475E-03 0,03541557 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,475E-03 0,03529945 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,475E-03 0,03518409 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,475E-03 0,03506949 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,475E-03 0,03495562 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,475E-03 0,0348425 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,475E-03 0,0347301 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,475E-03 0,03461843 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,475E-03 0,03450748 ! drug metabolic process GO:0017144 6 5 0,000 4,475E-03 0,03439723 ! stem cell division GO:0017145 11 5 0,000 4,475E-03 0,03428768 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,475E-03 0,03417883 ! organ regeneration GO:0031100 7 5 0,000 4,475E-03 0,03407067 ! carnitine metabolic process GO:0009437 7 5 0,000 4,475E-03 0,03396319 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,475E-03 0,03385639 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,475E-03 0,03375026 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 5,367E-03 0,04035633 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 5,367E-03 0,04023061 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 5,367E-03 0,04010567 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,367E-03 0,0399815 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 5,367E-03 0,0398581 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 5,367E-03 0,03973546 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 5,367E-03 0,03961357 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 5,367E-03 0,03949243 ! sleep GO:0030431 13 6 0,000 5,367E-03 0,03937203 ! response to oxygen radical GO:0000305 11 6 0,000 5,367E-03 0,03925235 ! positive regulation of axon extension GO:0045773 11 6 0,000 5,367E-03 0,03913341 ! myoblast cell fate commitment GO:0048625 16 6 0,000 5,367E-03 0,03901518 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 5,367E-03 0,03889766 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 5,367E-03 0,03878085 ! regulation of interferon-beta production GO:0032648 8 6 0,000 5,367E-03 0,03866474 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 5,367E-03 0,03854933 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 5,367E-03 0,0384346 ! forebrain regionalization GO:0021871 8 6 0,000 5,367E-03 0,03832055 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 5,367E-03 0,03820717 ! male meiosis GO:0007140 7 6 0,000 5,367E-03 0,03809447 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 5,367E-03 0,03798243 ! response to zinc ion GO:0010043 9 6 0,000 5,367E-03 0,03787104 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 5,367E-03 0,03776031 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 5,367E-03 0,03765022 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 5,367E-03 0,03754077 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 5,367E-03 0,03743196 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 5,367E-03 0,03732377 ! malate metabolic process GO:0006108 11 6 0,000 5,367E-03 0,03721621 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 5,367E-03 0,03710927 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 5,367E-03 0,03700294 ! protein refolding GO:0042026 15 6 0,000 5,367E-03 0,03689721 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 5,367E-03 0,03679209 ! opsonization GO:0008228 8 6 0,000 5,367E-03 0,03668757 ! mating behavior GO:0007617 7 6 0,000 5,367E-03 0,03658364 ! neuron remodeling GO:0016322 15 6 0,000 5,367E-03 0,0364803 ! erythrocyte maturation GO:0043249 7 6 0,000 5,367E-03 0,03637753 ! embryonic hemopoiesis GO:0035162 14 6 0,000 5,367E-03 0,03627535 ! equilibrioception GO:0050957 14 6 0,000 5,367E-03 0,03617374 ! protein amino acid dealkylation GO:0008214 12 6 0,000 5,367E-03 0,03607269 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 5,367E-03 0,03597221 ! photoreceptor cell development GO:0042461 10 6 0,000 5,367E-03 0,03587229 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 5,367E-03 0,03577292 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 5,367E-03 0,0356741 ! response to interferon-gamma GO:0034341 15 6 0,000 5,367E-03 0,03557583 ! toxin metabolic process GO:0009404 11 6 0,000 5,367E-03 0,03547809 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 5,367E-03 0,03538089 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,367E-03 0,03528422 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 5,367E-03 0,03518808 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 5,367E-03 0,03509246 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 5,367E-03 0,03499736 ! cGMP-mediated signaling GO:0019934 13 6 0,000 5,367E-03 0,03490277 ! activation of MAPKKK activity GO:0000185 12 6 0,000 5,367E-03 0,03480869 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 5,367E-03 0,03471512 ! thymic T cell selection GO:0045061 12 6 0,000 5,367E-03 0,03462205 ! protein lipoylation GO:0009249 10 6 0,000 5,367E-03 0,03452948 ! cysteine metabolic process GO:0006534 10 6 0,000 5,367E-03 0,0344374 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 5,367E-03 0,03434581 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,367E-03 0,03425471 ! glutamate catabolic process GO:0006538 10 6 0,000 5,367E-03 0,03416409 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 5,367E-03 0,03407394 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 5,367E-03 0,03398428 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 5,367E-03 0,03389508 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 5,367E-03 0,03380635 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 5,367E-03 0,03371808 ! hyperosmotic response GO:0006972 9 6 0,000 5,367E-03 0,03363027 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 5,367E-03 0,03354292 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 5,367E-03 0,03345602 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 5,367E-03 0,03336957 ! urea metabolic process GO:0019627 7 6 0,000 5,367E-03 0,03328357 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 5,367E-03 0,03319801 ! neutrophil activation GO:0042119 8 6 0,000 5,367E-03 0,03311288 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 5,367E-03 0,0330282 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 5,367E-03 0,03294394 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 5,367E-03 0,03286011 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,367E-03 0,03277671 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 5,367E-03 0,03269373 ! neuron apoptosis GO:0051402 9 6 0,000 5,367E-03 0,03261117 ! nucleoside salvage GO:0043174 9 6 0,000 5,367E-03 0,03252903 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 5,367E-03 0,0324473 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 5,367E-03 0,03236598 ! T cell mediated immunity GO:0002456 16 6 0,000 5,367E-03 0,03228506 ! negative regulation of platelet activation GO:0010544 9 6 0,000 5,367E-03 0,03220455 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 5,367E-03 0,03212444 ! carnitine transport GO:0015879 10 6 0,000 5,367E-03 0,03204473 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 5,367E-03 0,03196541 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,367E-03 0,03188648 ! positive regulation of exocytosis GO:0045921 8 6 0,000 5,367E-03 0,03180794 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 5,367E-03 0,03172979 ! 5S class rRNA transcription GO:0042791 11 6 0,000 5,367E-03 0,03165202 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 5,367E-03 0,03157463 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 5,367E-03 0,03149762 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 5,367E-03 0,03142098 ! sodium ion homeostasis GO:0055078 11 6 0,000 5,367E-03 0,03134472 ! establishment of spindle localization GO:0051293 12 6 0,000 5,367E-03 0,03126882 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 5,367E-03 0,0311933 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 5,367E-03 0,03111813 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 5,367E-03 0,03104333 ! neural nucleus development GO:0048857 14 6 0,000 5,367E-03 0,03096888 ! response to UV-C GO:0010225 11 6 0,000 5,367E-03 0,0308948 ! astrocyte development GO:0014002 15 6 0,000 5,367E-03 0,03082106 ! protein targeting to lysosome GO:0006622 10 6 0,000 5,367E-03 0,03074768 ! purine base biosynthetic process GO:0009113 17 6 0,000 5,367E-03 0,03067464 ! interaction with symbiont GO:0051702 13 6 0,000 5,367E-03 0,03060195 ! regulation of dendrite development GO:0050773 16 6 0,000 5,367E-03 0,03052961 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,367E-03 0,03045761 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 5,367E-03 0,03038594 ! response to copper ion GO:0046688 10 6 0,000 5,367E-03 0,03031461 ! response to exogenous dsRNA GO:0043330 10 6 0,000 5,367E-03 0,03024362 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 5,367E-03 0,03017295 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,367E-03 0,03010262 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,367E-03 0,03003262 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 5,367E-03 0,02996293 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 5,367E-03 0,02989358 ! regulation of dopamine secretion GO:0014059 14 6 0,000 5,367E-03 0,02982454 ! nucleoside catabolic process GO:0009164 7 6 0,000 5,367E-03 0,02975582 ! hair follicle maturation GO:0048820 7 6 0,000 5,367E-03 0,02968741 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 5,367E-03 0,02961932 ! Schwann cell development GO:0014044 15 6 0,000 5,367E-03 0,02955154 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 5,367E-03 0,02948407 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,367E-03 0,02941691 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 5,367E-03 0,02935006 ! subpallium development GO:0021544 10 6 0,000 5,367E-03 0,0292835 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 5,367E-03 0,02921725 ! histone ubiquitination GO:0016574 8 6 0,000 5,367E-03 0,0291513 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 5,367E-03 0,02908564 ! maintenance of organ identity GO:0048496 9 6 0,000 5,367E-03 0,02902028 ! G2 phase GO:0051319 16 6 0,000 5,367E-03 0,02895521 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 5,367E-03 0,02889044 ! establishment of planar polarity GO:0001736 7 6 0,000 5,367E-03 0,02882595 ! regulation of mast cell activation GO:0033003 12 6 0,000 5,367E-03 0,02876175 ! membrane to membrane docking GO:0022614 14 6 0,000 5,367E-03 0,02869783 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 5,367E-03 0,0286342 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 5,367E-03 0,02857085 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 5,367E-03 0,02850778 ! receptor internalization GO:0031623 10 6 0,000 5,367E-03 0,02844499 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 5,367E-03 0,02838247 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 5,367E-03 0,02832023 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,367E-03 0,02825826 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 5,367E-03 0,02819656 ! protein deubiquitination GO:0016579 14 6 0,000 5,367E-03 0,02813513 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 5,367E-03 0,02807397 ! protein destabilization GO:0031648 9 6 0,000 5,367E-03 0,02801307 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 5,367E-03 0,02795243 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 5,367E-03 0,02789206 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,367E-03 0,02783195 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 5,367E-03 0,0277721 ! progesterone metabolic process GO:0042448 10 6 0,000 5,367E-03 0,0277125 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 5,367E-03 0,02765316 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 5,367E-03 0,02759407 ! negative regulation of axon extension GO:0030517 21 6 0,000 5,367E-03 0,02753523 ! removal of superoxide radicals GO:0019430 11 6 0,000 5,367E-03 0,02747665 ! triglyceride catabolic process GO:0019433 10 6 0,000 5,367E-03 0,02741831 ! determination of adult lifespan GO:0008340 15 6 0,000 5,367E-03 0,02736022 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 5,367E-03 0,02730238 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 5,367E-03 0,02724478 ! cerebellar cortex formation GO:0021697 8 6 0,000 5,367E-03 0,02718742 ! catecholamine transport GO:0051937 9 6 0,000 5,367E-03 0,0271303 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 5,367E-03 0,02707343 ! sensory cilium assembly GO:0035058 10 6 0,000 5,367E-03 0,02701679 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,367E-03 0,02696039 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 5,367E-03 0,02690422 ! maternal placenta development GO:0001893 12 6 0,000 5,367E-03 0,02684828 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 5,367E-03 0,02679258 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 5,367E-03 0,02673711 ! negative regulation of B cell activation GO:0050869 13 6 0,000 5,367E-03 0,02668187 ! protein amino acid prenylation GO:0018346 16 6 0,000 5,367E-03 0,02662685 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,367E-03 0,02657207 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 5,367E-03 0,0265175 ! positive regulation of coagulation GO:0050820 12 6 0,000 5,367E-03 0,02646317 ! tRNA transcription GO:0009304 14 7 0,000 6,259E-03 0,03079726 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 6,259E-03 0,03073441 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 6,259E-03 0,03067182 ! behavioral response to cocaine GO:0048148 14 7 0,000 6,259E-03 0,03060948 ! regulation of helicase activity GO:0051095 15 7 0,000 6,259E-03 0,03054739 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 6,259E-03 0,03048555 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 6,259E-03 0,03042396 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 6,259E-03 0,03036263 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 6,259E-03 0,03030153 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 6,259E-03 0,03024069 ! prostate gland development GO:0030850 13 7 0,000 6,259E-03 0,03018008 ! nucleotide-sugar transport GO:0015780 12 7 0,000 6,259E-03 0,03011972 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,259E-03 0,03005961 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 6,259E-03 0,02999973 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 6,259E-03 0,02994008 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,259E-03 0,02988068 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 6,259E-03 0,02982151 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 6,259E-03 0,02976257 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 6,259E-03 0,02970387 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 6,259E-03 0,0296454 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 6,259E-03 0,02958716 ! SMAD protein complex assembly GO:0007183 12 7 0,000 6,259E-03 0,02952914 ! glycolipid transport GO:0046836 10 7 0,000 6,259E-03 0,02947135 ! protein amino acid sulfation GO:0006477 10 7 0,000 6,259E-03 0,02941379 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 6,259E-03 0,02935646 ! neuron adhesion GO:0007158 12 7 0,000 6,259E-03 0,02929934 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 6,259E-03 0,02924245 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 6,259E-03 0,02918578 ! actin-myosin filament sliding GO:0033275 11 7 0,000 6,259E-03 0,02912933 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 6,259E-03 0,02907309 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 6,259E-03 0,02901708 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 6,259E-03 0,02896127 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 6,259E-03 0,02890569 ! mRNA stabilization GO:0048255 18 7 0,000 6,259E-03 0,02885031 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 6,259E-03 0,02879515 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 6,259E-03 0,0287402 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 6,259E-03 0,02868545 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 6,259E-03 0,02863092 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,259E-03 0,02857659 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 6,259E-03 0,02852247 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 6,259E-03 0,02846855 ! lipoprotein transport GO:0042953 14 7 0,000 6,259E-03 0,02841483 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,259E-03 0,02836132 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,259E-03 0,02830801 ! rhythmic behavior GO:0007622 15 7 0,000 6,259E-03 0,0282549 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 6,259E-03 0,02820199 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 6,259E-03 0,02814928 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 6,259E-03 0,02809676 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 6,259E-03 0,02804444 ! regulation of odontogenesis GO:0042481 13 7 0,000 6,259E-03 0,02799231 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 6,259E-03 0,02794038 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 6,259E-03 0,02788863 ! mechanosensory behavior GO:0007638 14 7 0,000 6,259E-03 0,02783708 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 6,259E-03 0,02778572 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,259E-03 0,02773455 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 6,259E-03 0,02768357 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,259E-03 0,02763277 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,259E-03 0,02758217 ! spinal cord patterning GO:0021511 13 7 0,000 6,259E-03 0,02753174 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 6,259E-03 0,0274815 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 6,259E-03 0,02743144 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 6,259E-03 0,02738157 ! adrenal gland development GO:0030325 17 7 0,000 6,259E-03 0,02733187 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 6,259E-03 0,02728236 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 6,259E-03 0,02723302 ! ovulation GO:0030728 9 7 0,000 6,259E-03 0,02718387 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 6,259E-03 0,02713489 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 6,259E-03 0,02708608 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 6,259E-03 0,02703745 ! microtubule nucleation GO:0007020 20 7 0,000 6,259E-03 0,026989 ! proline biosynthetic process GO:0006561 10 7 0,000 6,259E-03 0,02694072 ! thyroid hormone generation GO:0006590 13 7 0,000 6,259E-03 0,02689261 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 6,259E-03 0,02684467 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 6,259E-03 0,02679691 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 6,259E-03 0,02674931 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,259E-03 0,02670188 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,259E-03 0,02665462 ! galactose metabolic process GO:0006012 13 7 0,000 6,259E-03 0,02660753 ! vesicle fusion GO:0006906 17 7 0,000 6,259E-03 0,0265606 ! response to dietary excess GO:0002021 8 7 0,000 6,259E-03 0,02651384 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 6,259E-03 0,02646724 ! intracellular pH reduction GO:0051452 11 7 0,000 6,259E-03 0,02642081 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 6,259E-03 0,02637454 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 6,259E-03 0,02632843 ! organ growth GO:0035265 15 7 0,000 6,259E-03 0,02628248 ! purine salvage GO:0043101 10 7 0,000 6,259E-03 0,02623669 ! nucleoside transport GO:0015858 8 7 0,000 6,259E-03 0,02619106 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 6,259E-03 0,02614559 ! parturition GO:0007567 14 7 0,000 6,259E-03 0,02610028 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 6,259E-03 0,02605513 ! rRNA modification GO:0000154 14 7 0,000 6,259E-03 0,02601012 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 6,259E-03 0,02596528 ! spindle checkpoint GO:0031577 15 7 0,000 6,259E-03 0,02592059 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 6,259E-03 0,02587605 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 6,259E-03 0,02583167 ! macrophage differentiation GO:0030225 11 7 0,000 6,259E-03 0,02578744 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,259E-03 0,02574335 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 6,259E-03 0,02569942 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 6,259E-03 0,02565564 ! hyaluronan metabolic process GO:0030212 8 7 0,000 6,259E-03 0,02561201 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 6,259E-03 0,02556853 ! anterograde axon cargo transport GO:0008089 18 7 0,000 6,259E-03 0,02552519 ! fibrinolysis GO:0042730 10 7 0,000 6,259E-03 0,025482 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 6,259E-03 0,02543896 ! eating behavior GO:0042755 7 7 0,000 6,259E-03 0,02539606 ! B cell lineage commitment GO:0002326 21 7 0,000 6,259E-03 0,0253533 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 6,259E-03 0,02531069 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 6,259E-03 0,02526823 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 6,259E-03 0,0252259 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 6,259E-03 0,02518372 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 6,259E-03 0,02514167 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 6,259E-03 0,02509977 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 6,259E-03 0,02505801 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 6,259E-03 0,02501638 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 6,259E-03 0,0249749 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 6,259E-03 0,02493355 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 6,259E-03 0,02489233 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 6,259E-03 0,02485126 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 6,259E-03 0,02481032 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 6,259E-03 0,02476951 ! regulation of meiosis GO:0040020 12 7 0,000 6,259E-03 0,02472884 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 6,259E-03 0,0246883 ! T cell lineage commitment GO:0002360 16 7 0,000 6,259E-03 0,02464789 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 6,259E-03 0,02460762 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 6,259E-03 0,02456748 ! oxygen homeostasis GO:0032364 12 7 0,000 6,259E-03 0,02452746 ! transcription termination GO:0006353 13 7 0,000 6,259E-03 0,02448758 ! response to tumor cell GO:0002347 13 7 0,000 6,259E-03 0,02444783 ! regulation of respiratory burst GO:0060263 11 7 0,000 6,259E-03 0,0244082 ! coenzyme A metabolic process GO:0015936 12 7 0,000 6,259E-03 0,02436871 ! anaphase GO:0051322 17 7 0,000 6,259E-03 0,02432934 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 6,259E-03 0,0242901 ! axonal fasciculation GO:0007413 18 7 0,000 6,259E-03 0,02425099 ! negative regulation of nuclear division GO:0051784 14 7 0,000 6,259E-03 0,024212 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 6,259E-03 0,02417313 ! peptidyl-threonine modification GO:0018210 25 7 0,000 6,259E-03 0,02413439 ! diuresis GO:0030146 12 7 0,000 6,259E-03 0,02409578 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 6,259E-03 0,02405729 ! thiamin metabolic process GO:0006772 7 7 0,000 6,259E-03 0,02401892 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,259E-03 0,02398067 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 6,259E-03 0,02394255 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 6,259E-03 0,02390454 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 6,259E-03 0,02386666 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,259E-03 0,0238289 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,259E-03 0,02379125 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,259E-03 0,02375373 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 6,259E-03 0,02371632 ! dopamine biosynthetic process GO:0042416 18 7 0,000 6,259E-03 0,02367903 ! glycolipid catabolic process GO:0019377 15 7 0,000 6,259E-03 0,02364186 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 6,259E-03 0,0236048 ! lymph node development GO:0048535 10 7 0,000 6,259E-03 0,02356786 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 6,259E-03 0,02353103 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,259E-03 0,02349433 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 6,259E-03 0,02345773 ! endosome to lysosome transport GO:0008333 11 7 0,000 6,259E-03 0,02342125 ! protein modification by small protein removal GO:0070646 16 7 0,000 6,259E-03 0,02338488 ! adult feeding behavior GO:0008343 9 7 0,000 6,259E-03 0,02334862 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 6,259E-03 0,02331248 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 6,259E-03 0,02327645 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 6,259E-03 0,02324053 ! muscle adaptation GO:0043500 14 7 0,000 6,259E-03 0,02320472 ! embryonic heart tube development GO:0035050 10 7 0,000 6,259E-03 0,02316902 ! retina homeostasis GO:0001895 12 7 0,000 6,259E-03 0,02313343 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 6,259E-03 0,02309795 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 6,259E-03 0,02306258 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 6,259E-03 0,02302731 ! protein prenylation GO:0018342 18 7 0,000 6,259E-03 0,02299216 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 6,259E-03 0,02295711 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 6,259E-03 0,02292216 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,259E-03 0,02288733 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 7,15E-03 0,02610599 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 7,15E-03 0,02606644 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 7,15E-03 0,026027 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 7,15E-03 0,02598768 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 7,15E-03 0,02594849 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 7,15E-03 0,02590941 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 7,15E-03 0,02587045 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 7,15E-03 0,0258316 ! neutral lipid catabolic process GO:0046461 13 8 0,000 7,15E-03 0,02579287 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 7,15E-03 0,02575426 ! meiotic prophase I GO:0007128 13 8 0,000 7,15E-03 0,02571577 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 7,15E-03 0,02567738 ! oligopeptide transport GO:0006857 15 8 0,000 7,15E-03 0,02563912 ! UTP metabolic process GO:0046051 8 8 0,000 7,15E-03 0,02560096 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 7,15E-03 0,02556292 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 7,15E-03 0,025525 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 7,15E-03 0,02548718 ! macrophage chemotaxis GO:0048246 12 8 0,000 7,15E-03 0,02544948 ! succinate metabolic process GO:0006105 14 8 0,000 7,15E-03 0,02541189 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,15E-03 0,02537441 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 7,15E-03 0,02533704 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 7,15E-03 0,02529978 ! T-helper 1 type immune response GO:0042088 12 8 0,000 7,15E-03 0,02526262 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 7,15E-03 0,02522558 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 7,15E-03 0,02518865 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,15E-03 0,02515182 ! ganglioside metabolic process GO:0001573 19 8 0,000 7,15E-03 0,02511511 ! reflex GO:0060004 16 8 0,000 7,15E-03 0,02507849 ! negative regulation of endocytosis GO:0045806 11 8 0,000 7,15E-03 0,02504199 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 7,15E-03 0,02500559 ! endothelial cell differentiation GO:0045446 17 8 0,000 7,15E-03 0,0249693 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 7,15E-03 0,02493311 ! glycerolipid catabolic process GO:0046503 13 8 0,000 7,15E-03 0,02489703 ! hemoglobin metabolic process GO:0020027 13 8 0,000 7,15E-03 0,02486105 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 7,15E-03 0,02482518 ! pigment granule organization GO:0048753 16 8 0,000 7,15E-03 0,02478941 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 7,15E-03 0,02475374 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 7,15E-03 0,02471817 ! astrocyte differentiation GO:0048708 18 8 0,000 7,15E-03 0,02468271 ! histidine metabolic process GO:0006547 16 8 0,000 7,15E-03 0,02464735 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 7,15E-03 0,02461208 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 7,15E-03 0,02457692 ! glycine catabolic process GO:0006546 13 8 0,000 7,15E-03 0,02454186 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 7,15E-03 0,0245069 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 7,15E-03 0,02447204 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 7,15E-03 0,02443728 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 7,15E-03 0,02440262 ! regulation of pigmentation during development GO:0048070 24 8 0,000 7,15E-03 0,02436806 ! melanin metabolic process GO:0006582 15 8 0,000 7,15E-03 0,02433359 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 7,15E-03 0,02429922 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,15E-03 0,02426495 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 7,15E-03 0,02423077 ! macrophage activation GO:0042116 12 8 0,000 7,15E-03 0,02419669 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 7,15E-03 0,02416271 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 7,15E-03 0,02412882 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 7,15E-03 0,02409502 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 7,15E-03 0,02406132 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 7,15E-03 0,02402772 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 7,15E-03 0,02399421 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,15E-03 0,02396079 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 7,15E-03 0,02392746 ! osteoblast development GO:0002076 16 8 0,000 7,15E-03 0,02389423 ! positive regulation of vasodilation GO:0045909 13 8 0,000 7,15E-03 0,02386109 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 7,15E-03 0,02382804 ! negative regulation of translational initiation GO:0045947 10 8 0,000 7,15E-03 0,02379509 ! Schwann cell differentiation GO:0014037 19 8 0,000 7,15E-03 0,02376222 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 7,15E-03 0,02372944 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 7,15E-03 0,02369676 ! response to UV-B GO:0010224 16 8 0,000 7,15E-03 0,02366416 ! protein targeting to vacuole GO:0006623 12 8 0,000 7,15E-03 0,02363166 ! protein retention in ER lumen GO:0006621 14 8 0,000 7,15E-03 0,02359924 ! intermediate filament organization GO:0045109 12 8 0,000 7,15E-03 0,02356691 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 7,15E-03 0,02353467 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 7,15E-03 0,02350252 ! cellular extravasation GO:0045123 12 8 0,000 7,15E-03 0,02347046 ! cardiac muscle cell development GO:0055013 13 8 0,000 7,15E-03 0,02343848 ! regulation of circadian rhythm GO:0042752 16 8 0,000 7,15E-03 0,02340659 ! response to antibiotic GO:0046677 11 8 0,000 7,15E-03 0,02337479 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 7,15E-03 0,02334308 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 7,15E-03 0,02331145 ! response to tropane GO:0014073 15 8 0,000 7,15E-03 0,0232799 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 7,15E-03 0,02324844 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 7,15E-03 0,02321707 ! melanosome transport GO:0032402 13 8 0,000 7,15E-03 0,02318578 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 7,15E-03 0,02315457 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 7,15E-03 0,02312345 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 7,15E-03 0,02309241 ! multicellular organismal aging GO:0010259 18 8 0,000 7,15E-03 0,02306146 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 7,15E-03 0,02303059 ! dendrite morphogenesis GO:0048813 13 8 0,000 7,15E-03 0,0229998 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 7,15E-03 0,02296909 ! nucleosome disassembly GO:0006337 14 8 0,000 7,15E-03 0,02293846 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 7,15E-03 0,02290792 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 7,15E-03 0,02287746 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,15E-03 0,02284707 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 7,15E-03 0,02281677 ! establishment of chromosome localization GO:0051303 12 8 0,000 7,15E-03 0,02278655 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 7,15E-03 0,02275641 ! intracellular lipid transport GO:0032365 13 8 0,000 7,15E-03 0,02272635 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 7,15E-03 0,02269637 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,15E-03 0,02266647 ! regulation of macrophage activation GO:0043030 15 8 0,000 7,15E-03 0,02263664 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 7,15E-03 0,0226069 ! positive regulation of epidermis development GO:0045684 13 8 0,000 7,15E-03 0,02257723 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 7,15E-03 0,02254764 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 7,15E-03 0,02251812 ! hormone catabolic process GO:0042447 17 8 0,000 7,15E-03 0,02248869 ! positive regulation of glucose import GO:0046326 8 8 0,000 7,15E-03 0,02245933 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 7,15E-03 0,02243005 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 7,15E-03 0,02240084 ! ATP catabolic process GO:0006200 11 8 0,000 7,15E-03 0,02237171 ! blastocyst growth GO:0001832 19 8 0,000 7,15E-03 0,02234266 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 7,15E-03 0,02231368 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 7,15E-03 0,02228478 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 7,15E-03 0,02225595 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 7,15E-03 0,02222719 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,15E-03 0,02219851 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 7,15E-03 0,02216991 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 7,15E-03 0,02214137 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 7,15E-03 0,02211291 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 7,15E-03 0,02208453 ! amino sugar catabolic process GO:0046348 10 8 0,000 7,15E-03 0,02205621 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 7,15E-03 0,02202797 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 7,15E-03 0,0219998 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 7,15E-03 0,02197171 ! behavioral response to nicotine GO:0035095 12 8 0,000 7,15E-03 0,02194368 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,15E-03 0,02191573 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 7,15E-03 0,02188785 ! NAD biosynthetic process GO:0009435 13 8 0,000 7,15E-03 0,02186003 ! regulation of developmental growth GO:0048638 15 9 0,000 8,041E-03 0,02455074 ! axon extension GO:0048675 15 9 0,000 8,041E-03 0,02451962 ! autophagic vacuole formation GO:0000045 15 9 0,000 8,041E-03 0,02448858 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 8,041E-03 0,02445762 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 8,041E-03 0,02442674 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 8,041E-03 0,02439594 ! pentose-phosphate shunt GO:0006098 16 9 0,000 8,041E-03 0,02436521 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 8,041E-03 0,02433457 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 8,041E-03 0,024304 ! cell proliferation in forebrain GO:0021846 15 9 0,000 8,041E-03 0,0242735 ! reproductive behavior GO:0019098 19 9 0,000 8,041E-03 0,02424308 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 8,041E-03 0,02421274 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 8,041E-03 0,02418248 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,041E-03 0,02415229 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 8,041E-03 0,02412217 ! GTP metabolic process GO:0046039 9 9 0,000 8,041E-03 0,02409213 ! RNA methylation GO:0001510 15 9 0,000 8,041E-03 0,02406216 ! elastic fiber assembly GO:0048251 15 9 0,000 8,041E-03 0,02403227 ! induction of positive chemotaxis GO:0050930 15 9 0,000 8,041E-03 0,02400246 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 8,041E-03 0,02397271 ! artery development GO:0060840 24 9 0,000 8,041E-03 0,02394305 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 8,041E-03 0,02391345 ! regulation of glycolysis GO:0006110 21 9 0,000 8,041E-03 0,02388393 ! cerebral cortex cell migration GO:0021795 15 9 0,000 8,041E-03 0,02385448 ! keratinocyte proliferation GO:0043616 14 9 0,000 8,041E-03 0,0238251 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 8,041E-03 0,02379579 ! chemosensory behavior GO:0007635 20 9 0,000 8,041E-03 0,02376656 ! microtubule bundle formation GO:0001578 21 9 0,000 8,041E-03 0,0237374 ! middle ear morphogenesis GO:0042474 14 9 0,000 8,041E-03 0,02370831 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 8,041E-03 0,02367929 ! leukocyte degranulation GO:0043299 16 9 0,000 8,041E-03 0,02365034 ! bile acid and bile salt transport GO:0015721 13 9 0,000 8,041E-03 0,02362147 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 8,041E-03 0,02359266 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 8,041E-03 0,02356392 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 8,041E-03 0,02353526 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 8,041E-03 0,02350666 ! protein targeting to ER GO:0045047 22 9 0,000 8,041E-03 0,02347813 ! ceramide biosynthetic process GO:0046513 19 9 0,000 8,041E-03 0,02344967 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 8,041E-03 0,02342128 ! T cell selection GO:0045058 23 9 0,000 8,041E-03 0,02339296 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 8,041E-03 0,02336471 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 8,041E-03 0,02333653 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,041E-03 0,02330841 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 8,041E-03 0,02328036 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 8,041E-03 0,02325238 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,041E-03 0,02322447 ! regulation of type I interferon production GO:0032479 12 9 0,000 8,041E-03 0,02319662 ! mannose metabolic process GO:0006013 13 9 0,000 8,041E-03 0,02316884 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 8,041E-03 0,02314113 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 8,041E-03 0,02311348 ! Rac protein signal transduction GO:0016601 17 9 0,000 8,041E-03 0,0230859 ! receptor clustering GO:0043113 18 9 0,000 8,041E-03 0,02305838 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 8,041E-03 0,02303093 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 8,041E-03 0,02300354 ! ruffle organization GO:0031529 15 9 0,000 8,041E-03 0,02297622 ! retinol metabolic process GO:0042572 18 9 0,000 8,041E-03 0,02294897 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 8,041E-03 0,02292178 ! behavioral fear response GO:0001662 22 9 0,000 8,041E-03 0,02289465 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 8,041E-03 0,02286759 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 8,041E-03 0,02284059 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 8,041E-03 0,02281366 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 8,041E-03 0,02278679 ! protein heterooligomerization GO:0051291 16 9 0,000 8,041E-03 0,02275998 ! oligodendrocyte development GO:0014003 10 9 0,000 8,041E-03 0,02273323 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 8,041E-03 0,02270655 ! segment specification GO:0007379 13 9 0,000 8,041E-03 0,02267993 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 8,041E-03 0,02265337 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 8,041E-03 0,02262688 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 8,041E-03 0,02260044 ! response to amine stimulus GO:0014075 13 9 0,000 8,041E-03 0,02257407 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 8,041E-03 0,02254776 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 8,041E-03 0,02252151 ! erythrocyte development GO:0048821 15 9 0,000 8,041E-03 0,02249533 ! gas homeostasis GO:0033483 16 9 0,000 8,041E-03 0,0224692 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 8,041E-03 0,02244313 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 8,041E-03 0,02241713 ! renal water homeostasis GO:0003091 14 9 0,000 8,041E-03 0,02239118 ! postreplication repair GO:0006301 22 9 0,000 8,041E-03 0,0223653 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 8,041E-03 0,02233947 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 8,041E-03 0,0223137 ! icosanoid secretion GO:0032309 15 9 0,000 8,041E-03 0,022288 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 8,041E-03 0,02226235 ! cerebellum morphogenesis GO:0021587 14 9 0,000 8,041E-03 0,02223676 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 8,041E-03 0,02221123 ! regulation of cell division GO:0051302 15 9 0,000 8,041E-03 0,02218576 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 8,041E-03 0,02216034 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 8,041E-03 0,02213499 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 8,041E-03 0,02210969 ! sterol catabolic process GO:0016127 11 9 0,000 8,041E-03 0,02208445 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 8,041E-03 0,02205927 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 8,041E-03 0,02203415 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 8,041E-03 0,02200908 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 8,041E-03 0,02198407 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 8,041E-03 0,02195912 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 8,041E-03 0,02193422 ! musculoskeletal movement GO:0050881 14 9 0,000 8,041E-03 0,02190938 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 8,041E-03 0,02188459 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 8,041E-03 0,02185987 ! regulation of synaptogenesis GO:0051963 15 9 0,000 8,041E-03 0,02183519 ! purine base metabolic process GO:0006144 21 9 0,000 8,041E-03 0,02181058 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 8,041E-03 0,02178601 ! pigment granule transport GO:0051904 17 9 0,000 8,041E-03 0,02176151 ! regulation of fibrinolysis GO:0051917 16 9 0,000 8,041E-03 0,02173706 ! regulation of telomere maintenance GO:0032204 14 9 0,000 8,041E-03 0,02171266 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 8,041E-03 0,02168832 ! regulation of muscle adaptation GO:0043502 14 9 0,000 8,041E-03 0,02166403 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,041E-03 0,0216398 ! mitochondrion localization GO:0051646 15 9 0,000 8,041E-03 0,02161562 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,93E-03 0,02398021 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,93E-03 0,02395347 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 8,93E-03 0,0239268 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,93E-03 0,02390018 ! synapsis GO:0007129 13 10 0,000 8,93E-03 0,02387363 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,93E-03 0,02384713 ! N-glycan processing GO:0006491 20 10 0,000 8,93E-03 0,02382069 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 8,93E-03 0,02379431 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,93E-03 0,02376799 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,93E-03 0,02374173 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,93E-03 0,02371552 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,93E-03 0,02368938 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,93E-03 0,02366329 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,93E-03 0,02363725 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,93E-03 0,02361128 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,93E-03 0,02358536 ! androgen metabolic process GO:0008209 17 10 0,000 8,93E-03 0,0235595 ! phospholipid efflux GO:0033700 16 10 0,000 8,93E-03 0,0235337 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,93E-03 0,02350795 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,93E-03 0,02348226 ! lung alveolus development GO:0048286 26 10 0,000 8,93E-03 0,02345662 ! pathogenesis GO:0009405 13 10 0,000 8,93E-03 0,02343104 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,93E-03 0,02340552 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,93E-03 0,02338005 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,93E-03 0,02335464 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,93E-03 0,02332928 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,93E-03 0,02330397 ! endoderm development GO:0007492 16 10 0,000 8,93E-03 0,02327873 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,93E-03 0,02325353 ! arginine catabolic process GO:0006527 13 10 0,000 8,93E-03 0,02322839 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,93E-03 0,02320331 ! proline metabolic process GO:0006560 13 10 0,000 8,93E-03 0,02317828 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,93E-03 0,0231533 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,93E-03 0,02312838 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,93E-03 0,02310351 ! V(D)J recombination GO:0033151 28 10 0,000 8,93E-03 0,02307869 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,93E-03 0,02305393 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,93E-03 0,02302922 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 8,93E-03 0,02300457 ! B cell proliferation GO:0042100 18 10 0,000 8,93E-03 0,02297996 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,93E-03 0,02295541 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,93E-03 0,02293091 ! multicellular organism growth GO:0035264 18 10 0,000 8,93E-03 0,02290647 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,93E-03 0,02288207 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,93E-03 0,02285773 ! epithelial cell development GO:0002064 20 10 0,000 8,93E-03 0,02283344 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,93E-03 0,0228092 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,93E-03 0,02278501 ! macroautophagy GO:0016236 17 10 0,000 8,93E-03 0,02276087 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,93E-03 0,02273679 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,93E-03 0,02271275 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,93E-03 0,02268877 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,93E-03 0,02266484 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,93E-03 0,02264095 ! copper ion homeostasis GO:0055070 13 10 0,000 8,93E-03 0,02261712 ! regulation of bone resorption GO:0045124 25 10 0,000 8,93E-03 0,02259334 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,93E-03 0,02256961 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,93E-03 0,02254592 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,93E-03 0,02252229 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,93E-03 0,02249871 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,93E-03 0,02247517 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,93E-03 0,02245169 ! blastoderm segmentation GO:0007350 18 10 0,000 8,93E-03 0,02242825 ! response to dsRNA GO:0043331 20 10 0,000 8,93E-03 0,02240486 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,93E-03 0,02238153 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,93E-03 0,02235824 ! melanosome localization GO:0032400 16 10 0,000 8,93E-03 0,02233499 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,93E-03 0,0223118 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,93E-03 0,02228866 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,93E-03 0,02226556 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,93E-03 0,02224251 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 8,93E-03 0,02221951 ! mRNA cleavage GO:0006379 17 10 0,000 8,93E-03 0,02219655 ! protein sumoylation GO:0016925 15 10 0,000 8,93E-03 0,02217365 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,93E-03 0,02215079 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,93E-03 0,02212798 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,93E-03 0,02210521 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,93E-03 0,02208249 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,93E-03 0,02205982 ! salivary gland development GO:0007431 27 10 0,000 8,93E-03 0,02203719 ! prophase GO:0051324 15 10 0,000 8,93E-03 0,02201461 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,93E-03 0,02199208 ! apical protein localization GO:0045176 15 10 0,000 8,93E-03 0,0219696 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,93E-03 0,02194715 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,93E-03 0,02192476 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,93E-03 0,02190241 ! midbrain development GO:0030901 13 10 0,000 8,93E-03 0,02188011 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,93E-03 0,02185785 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,93E-03 0,02183563 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,93E-03 0,02181347 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,93E-03 0,02179134 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,93E-03 0,02176926 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,93E-03 0,02174723 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,93E-03 0,02172524 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,93E-03 0,0217033 ! oocyte development GO:0048599 17 10 0,000 8,93E-03 0,0216814 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,93E-03 0,02165954 ! blastocyst formation GO:0001825 17 10 0,000 8,93E-03 0,02163773 ! cerebellar cortex development GO:0021695 15 10 0,000 8,93E-03 0,02161596 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 8,93E-03 0,02159424 ! activation of innate immune response GO:0002218 12 10 0,000 8,93E-03 0,02157255 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,93E-03 0,02155092 ! response to nicotine GO:0035094 20 10 0,000 8,93E-03 0,02152932 ! establishment of cell polarity GO:0030010 16 10 0,000 8,93E-03 0,02150777 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,93E-03 0,02148626 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,93E-03 0,0214648 ! localization within membrane GO:0051668 20 10 0,000 8,93E-03 0,02144338 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,819E-03 0,02355404 ! respiratory burst GO:0045730 17 11 0,000 9,819E-03 0,02353058 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,819E-03 0,02350716 ! neuron fate specification GO:0048665 17 11 0,000 9,819E-03 0,0234838 ! telencephalon cell migration GO:0022029 20 11 0,000 9,819E-03 0,02346048 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 9,819E-03 0,0234372 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,819E-03 0,02341397 ! thyroid gland development GO:0030878 26 11 0,000 9,819E-03 0,02339079 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,819E-03 0,02336766 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,819E-03 0,02334456 ! Golgi vesicle budding GO:0048194 22 11 0,000 9,819E-03 0,02332152 ! response to pain GO:0048265 24 11 0,000 9,819E-03 0,02329852 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,819E-03 0,02327557 ! T cell proliferation GO:0042098 26 11 0,000 9,819E-03 0,02325266 ! blood vessel remodeling GO:0001974 29 11 0,000 9,819E-03 0,02322979 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,819E-03 0,02320697 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 9,819E-03 0,0231842 ! bone resorption GO:0045453 16 11 0,000 9,819E-03 0,02316147 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,819E-03 0,02313879 ! ventral spinal cord development GO:0021517 21 11 0,000 9,819E-03 0,02311614 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,819E-03 0,02309355 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,819E-03 0,023071 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,819E-03 0,02304849 ! melanocyte differentiation GO:0030318 21 11 0,000 9,819E-03 0,02302602 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,819E-03 0,0230036 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,819E-03 0,02298123 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,819E-03 0,02295889 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,819E-03 0,0229366 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,819E-03 0,02291435 ! lipid digestion GO:0044241 18 11 0,000 9,819E-03 0,02289215 ! substrate-bound cell migration GO:0006929 13 11 0,000 9,819E-03 0,02286999 ! UV protection GO:0009650 19 11 0,000 9,819E-03 0,02284787 ! adult heart development GO:0007512 14 11 0,000 9,819E-03 0,0228258 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,819E-03 0,02280376 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,819E-03 0,02278177 ! temperature homeostasis GO:0001659 17 11 0,000 9,819E-03 0,02275983 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,819E-03 0,02273792 ! negative regulation of ossification GO:0030279 26 11 0,000 9,819E-03 0,02271606 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,819E-03 0,02269424 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,819E-03 0,02267246 ! regulation of organ growth GO:0046620 13 11 0,000 9,819E-03 0,02265072 ! pigment granule localization GO:0051875 20 11 0,000 9,819E-03 0,02262902 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,819E-03 0,02260737 ! vasoconstriction GO:0042310 18 11 0,000 9,819E-03 0,02258575 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,819E-03 0,02256418 ! embryonic axis specification GO:0000578 18 11 0,000 9,819E-03 0,02254265 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,819E-03 0,02252116 ! snRNA metabolic process GO:0016073 24 11 0,000 9,819E-03 0,02249971 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,819E-03 0,02247831 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,819E-03 0,02245694 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,819E-03 0,02243561 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,819E-03 0,02241433 ! zymogen activation GO:0031638 15 11 0,000 9,819E-03 0,02239308 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,819E-03 0,02237187 ! neuroblast proliferation GO:0007405 24 11 0,000 9,819E-03 0,02235071 ! nucleosome positioning GO:0016584 15 11 0,000 9,819E-03 0,02232958 ! regulation of isotype switching GO:0045191 22 11 0,000 9,819E-03 0,0223085 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,819E-03 0,02228745 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,819E-03 0,02226645 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,819E-03 0,02224548 ! acid secretion GO:0046717 18 11 0,000 9,819E-03 0,02222455 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,819E-03 0,02220366 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,819E-03 0,02218282 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,819E-03 0,02216201 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,819E-03 0,02214124 ! oocyte differentiation GO:0009994 18 11 0,000 9,819E-03 0,02212051 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,819E-03 0,02209981 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 9,819E-03 0,02207916 ! cholesterol efflux GO:0033344 19 11 0,000 9,819E-03 0,02205854 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,819E-03 0,02203797 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,819E-03 0,02201743 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,819E-03 0,02199693 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,819E-03 0,02197646 ! embryonic gut development GO:0048566 15 11 0,000 9,819E-03 0,02195604 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,819E-03 0,02193565 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 9,819E-03 0,02191531 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,819E-03 0,02189499 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,819E-03 0,02187472 ! defense response to fungus GO:0050832 13 11 0,000 9,819E-03 0,02185449 ! developmental induction GO:0031128 19 11 0,000 9,819E-03 0,02183429 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 9,819E-03 0,02181413 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,819E-03 0,021794 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,819E-03 0,02177392 ! sequestering of metal ion GO:0051238 14 11 0,000 9,819E-03 0,02175387 ! lamellipodium assembly GO:0030032 20 11 0,000 9,819E-03 0,02173385 ! regulation of embryonic development GO:0045995 27 11 0,000 9,819E-03 0,02171388 ! nucleus localization GO:0051647 19 11 0,000 9,819E-03 0,02169394 ! regulation of synapse organization GO:0050807 17 11 0,000 9,819E-03 0,02167404 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0107071 0,02361255 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0107071 0,02359092 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0107071 0,02356934 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0107071 0,0235478 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0107071 0,02352629 ! virus-host interaction GO:0019048 29 12 0,000 0,0107071 0,02350482 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0107071 0,0234834 ! cartilage condensation GO:0001502 20 12 0,000 0,0107071 0,02346201 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0107071 0,02344066 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0107071 0,02341935 ! protein complex disassembly GO:0043241 27 12 0,000 0,0107071 0,02339808 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0107071 0,02337685 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0107071 0,02335566 ! hippocampus development GO:0021766 26 12 0,000 0,0107071 0,0233345 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0107071 0,02331338 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0107071 0,0232923 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0107071 0,02327126 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0107071 0,02325026 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0107071 0,02322929 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0107071 0,02320837 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0107071 0,02318748 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0107071 0,02316663 ! drug transport GO:0015893 16 12 0,000 0,0107071 0,02314581 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0107071 0,02312503 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0107071 0,02310429 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0107071 0,02308359 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0107071 0,02306293 ! focal adhesion formation GO:0048041 35 12 0,000 0,0107071 0,0230423 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0107071 0,02302171 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0107071 0,02300115 ! forebrain cell migration GO:0021885 21 12 0,000 0,0107071 0,02298063 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0107071 0,02296015 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0107071 0,0229397 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0107071 0,0229193 ! entry into host cell GO:0030260 32 12 0,000 0,0107071 0,02289892 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0107071 0,02287859 ! monoamine transport GO:0015844 18 12 0,000 0,0107071 0,02285829 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0107071 0,02283802 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0107071 0,02281779 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0107071 0,0227976 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0107071 0,02277744 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0107071 0,02275732 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0107071 0,02273724 ! protein homotetramerization GO:0051289 21 12 0,000 0,0107071 0,02271719 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0107071 0,02269717 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0107071 0,02267719 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0107071 0,02265725 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0107071 0,02263734 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0107071 0,02261746 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0107071 0,02259762 ! cranial nerve development GO:0021545 20 12 0,000 0,0107071 0,02257782 ! fucose catabolic process GO:0019317 22 12 0,000 0,0107071 0,02255805 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0107071 0,02253831 ! histone acetylation GO:0016573 26 12 0,000 0,0107071 0,02251861 ! histone methylation GO:0016571 26 12 0,000 0,0107071 0,02249894 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0107071 0,02247931 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0107071 0,02245971 ! gland morphogenesis GO:0022612 29 12 0,000 0,0107071 0,02244015 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0107071 0,02242062 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0107071 0,02240112 ! T cell homeostasis GO:0043029 25 12 0,000 0,0107071 0,02238166 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0107071 0,02236223 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0107071 0,02234283 ! spleen development GO:0048536 22 12 0,000 0,0107071 0,02232347 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0107071 0,02230415 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0107071 0,02228485 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0107071 0,02226559 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0107071 0,02224636 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0107071 0,02222717 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0107071 0,02220801 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0107071 0,02218888 ! response to cold GO:0009409 17 12 0,000 0,0107071 0,02216978 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0107071 0,02215072 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0107071 0,02213169 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01159436 0,02394509 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01159436 0,02392456 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01159436 0,02390405 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01159436 0,02388359 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01159436 0,02386316 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01159436 0,02384276 ! lipid localization GO:0010876 28 13 0,000 0,01159436 0,0238224 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01159436 0,02380207 ! organelle fusion GO:0048284 32 13 0,000 0,01159436 0,02378178 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01159436 0,02376153 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01159436 0,0237413 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01159436 0,02372111 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01159436 0,02370096 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01159436 0,02368084 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01159436 0,02366076 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01159436 0,0236407 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01159436 0,02362069 ! methionine metabolic process GO:0006555 27 13 0,000 0,01159436 0,0236007 ! plasma membrane organization GO:0007009 24 13 0,000 0,01159436 0,02358075 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01159436 0,02356084 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01159436 0,02354095 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01159436 0,02352111 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01159436 0,02350129 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01159436 0,02348151 ! response to X-ray GO:0010165 25 13 0,000 0,01159436 0,02346176 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01159436 0,02344204 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01159436 0,02342236 ! exocrine system development GO:0035272 32 13 0,000 0,01159436 0,02340271 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01159436 0,02338309 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01159436 0,02336351 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01159436 0,02334396 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01159436 0,02332444 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01159436 0,02330496 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01159436 0,0232855 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01159436 0,02326608 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01159436 0,02324669 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01159436 0,02322734 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01159436 0,02320801 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01159436 0,02318872 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01159436 0,02316946 ! ribosome assembly GO:0042255 17 13 0,000 0,01159436 0,02315023 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01159436 0,02313104 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01159436 0,02311187 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01159436 0,02309274 ! chromatin silencing GO:0006342 26 13 0,000 0,01159436 0,02307364 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01159436 0,02305457 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01159436 0,02303553 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01159436 0,02301653 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01159436 0,02299755 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01159436 0,02297861 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01159436 0,0229597 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01159436 0,02294082 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01159436 0,02292196 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01159436 0,02290315 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01159436 0,02288436 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01159436 0,0228656 ! embryonic placenta development GO:0001892 23 13 0,000 0,01159436 0,02284687 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01159436 0,02282818 ! insulin secretion GO:0030073 23 13 0,000 0,01159436 0,02280951 ! actin filament polymerization GO:0030041 24 13 0,000 0,01159436 0,02279088 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01159436 0,02277227 ! acrosome reaction GO:0007340 18 13 0,000 0,01159436 0,0227537 ! rRNA transcription GO:0009303 25 14 0,000 0,01248085 0,02447346 ! lactation GO:0007595 26 14 0,000 0,01248085 0,02445353 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01248085 0,02443363 ! reproductive cellular process GO:0048610 20 14 0,000 0,01248085 0,02441376 ! tRNA modification GO:0006400 20 14 0,000 0,01248085 0,02439393 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01248085 0,02437413 ! regulation of S phase GO:0033261 23 14 0,000 0,01248085 0,02435436 ! water transport GO:0006833 21 14 0,000 0,01248085 0,02433463 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01248085 0,02431492 ! non-recombinational repair GO:0000726 25 14 0,000 0,01248085 0,02429525 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01248085 0,02427561 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01248085 0,024256 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01248085 0,02423643 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01248085 0,02421688 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01248085 0,02419737 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01248085 0,02417788 ! palate development GO:0060021 31 14 0,000 0,01248085 0,02415843 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01248085 0,02413901 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01248085 0,02411962 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01248085 0,02410027 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01248085 0,02408094 ! arginine metabolic process GO:0006525 17 14 0,000 0,01248085 0,02406164 ! regulation of heart rate GO:0002027 24 14 0,000 0,01248085 0,02404238 ! organic alcohol transport GO:0015850 29 14 0,000 0,01248085 0,02402314 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01248085 0,02400394 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01248085 0,02398477 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01248085 0,02396563 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01248085 0,02394652 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01248085 0,02392743 ! L-amino acid transport GO:0015807 30 14 0,000 0,01248085 0,02390838 ! bone mineralization GO:0030282 17 14 0,000 0,01248085 0,02388936 ! stem cell development GO:0048864 43 14 0,000 0,01248085 0,02387037 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01248085 0,02385141 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01248085 0,02383248 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01248085 0,02381359 ! cerebellum development GO:0021549 21 14 0,000 0,01248085 0,02379472 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01248085 0,02377588 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01248085 0,02375707 ! response to gamma radiation GO:0010332 28 14 0,000 0,01248085 0,02373829 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01248085 0,02371953 ! cofactor transport GO:0051181 26 14 0,000 0,01248085 0,02370081 ! NADP metabolic process GO:0006739 24 14 0,000 0,01248085 0,02368212 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01248085 0,02366346 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01248085 0,02364483 ! intestinal absorption GO:0050892 25 14 0,000 0,01248085 0,02362622 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01248085 0,02360765 ! oxygen transport GO:0015671 21 14 0,000 0,01248085 0,02358911 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01248085 0,02357059 ! male genitalia development GO:0030539 24 14 0,000 0,01248085 0,0235521 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01248085 0,02353364 ! regulation of axon extension GO:0030516 37 14 0,000 0,01248085 0,02351522 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01248085 0,02349682 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01248085 0,02347844 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01336658 0,02512499 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01336658 0,02510538 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01336658 0,02508579 ! superoxide anion generation GO:0042554 20 15 0,000 0,01336658 0,02506624 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01336658 0,02504672 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01336658 0,02502723 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01336658 0,02500777 ! copper ion transport GO:0006825 20 15 0,000 0,01336658 0,02498834 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01336658 0,02496893 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01336658 0,02494956 ! sulfate transport GO:0008272 23 15 0,000 0,01336658 0,02493022 ! response to cAMP GO:0051591 22 15 0,000 0,01336658 0,02491091 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01336658 0,02489163 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01336658 0,02487238 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01336658 0,02485316 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01336658 0,02483397 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01336658 0,02481481 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01336658 0,02479567 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01336658 0,02477657 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01336658 0,0247575 ! pituitary gland development GO:0021983 29 15 0,000 0,01336658 0,02473845 ! vesicle coating GO:0006901 33 15 0,000 0,01336658 0,02471944 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01336658 0,02470045 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01336658 0,0246815 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01336658 0,02466257 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01336658 0,02464367 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01336658 0,0246248 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01336658 0,02460596 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01336658 0,02458715 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01336658 0,02456836 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01336658 0,02454961 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01336658 0,02453088 ! histone deacetylation GO:0016575 20 15 0,000 0,01336658 0,02451219 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01336658 0,02449352 ! tissue regeneration GO:0042246 26 15 0,000 0,01336658 0,02447488 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01336658 0,02445626 ! water homeostasis GO:0030104 27 15 0,000 0,01336658 0,02443768 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01336658 0,02441913 ! muscle maintenance GO:0046716 26 15 0,000 0,01336658 0,0244006 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01336658 0,0243821 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01336658 0,02436363 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01336658 0,02434518 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01336658 0,02432677 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01336658 0,02430838 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01336658 0,02429002 ! detection of bacterium GO:0016045 18 15 0,000 0,01336658 0,02427169 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01336658 0,02425338 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01336658 0,02423511 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01336658 0,02421686 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01336658 0,02419864 ! peptide hormone processing GO:0016486 23 15 0,000 0,01336658 0,02418044 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01425154 0,02576199 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01425154 0,02574265 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01425154 0,02572333 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01425154 0,02570405 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01425154 0,0256848 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01425154 0,02566557 ! bone remodeling GO:0046849 27 16 0,000 0,01425154 0,02564638 ! filopodium assembly GO:0046847 32 16 0,000 0,01425154 0,02562721 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01425154 0,02560807 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01425154 0,02558896 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01425154 0,02556988 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01425154 0,02555082 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01425154 0,0255318 ! startle response GO:0001964 28 16 0,000 0,01425154 0,0255128 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01425154 0,02549383 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01425154 0,02547489 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01425154 0,02545598 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01425154 0,0254371 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01425154 0,02541824 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01425154 0,02539941 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01425154 0,02538061 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01425154 0,02536184 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01425154 0,02534309 ! response to osmotic stress GO:0006970 25 16 0,000 0,01425154 0,02532438 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01425154 0,02530569 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01425154 0,02528702 ! fructose metabolic process GO:0006000 25 16 0,000 0,01425154 0,02526839 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01425154 0,02524978 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01425154 0,0252312 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01425154 0,02521265 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01425154 0,02519413 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01425154 0,02517563 ! axon cargo transport GO:0008088 43 16 0,000 0,01425154 0,02515716 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01425154 0,02513871 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01425154 0,0251203 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01425154 0,02510191 ! DNA replication initiation GO:0006270 27 16 0,000 0,01425154 0,02508354 ! neuron recognition GO:0008038 35 16 0,000 0,01425154 0,02506521 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01425154 0,0250469 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01425154 0,02502862 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01425154 0,02501036 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01425154 0,02499213 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01425154 0,02497393 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01425154 0,02495575 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01425154 0,0249376 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01425154 0,02491948 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01425154 0,02490138 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01425154 0,02488331 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01425154 0,02486527 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01425154 0,02484725 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01425154 0,02482926 ! defense response to virus GO:0051607 37 16 0,000 0,01425154 0,02481129 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01513574 0,02633159 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01513574 0,02631256 ! metencephalon development GO:0022037 30 17 0,000 0,01513574 0,02629356 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01513574 0,02627459 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01513574 0,02625565 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01513574 0,02623673 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01513574 0,02621784 ! signal complex assembly GO:0007172 41 17 0,000 0,01513574 0,02619898 ! endothelial cell migration GO:0043542 28 17 0,000 0,01513574 0,02618015 ! inositol metabolic process GO:0006020 28 17 0,000 0,01513574 0,02616134 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01513574 0,02614256 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01513574 0,0261238 ! glial cell development GO:0021782 27 17 0,000 0,01513574 0,02610508 ! limbic system development GO:0021761 36 17 0,000 0,01513574 0,02608638 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01513574 0,0260677 ! adult walking behavior GO:0007628 33 17 0,000 0,01513574 0,02604906 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01513574 0,02603044 ! heart looping GO:0001947 30 17 0,000 0,01513574 0,02601184 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01513574 0,02599328 ! myoblast differentiation GO:0045445 45 17 0,000 0,01513574 0,02597474 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01513574 0,02595622 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01513574 0,02593774 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01513574 0,02591928 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01513574 0,02590084 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01513574 0,02588243 ! glycine metabolic process GO:0006544 28 17 0,000 0,01513574 0,02586405 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01513574 0,02584569 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01513574 0,02582736 ! NAD metabolic process GO:0019674 29 17 0,000 0,01513574 0,02580906 ! membrane budding GO:0006900 37 17 0,000 0,01513574 0,02579078 ! DNA integration GO:0015074 29 17 0,000 0,01513574 0,02577253 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01513574 0,0257543 ! regulation of protein binding GO:0043393 33 17 0,000 0,01513574 0,0257361 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01513574 0,02571793 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01513574 0,02569978 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01513574 0,02568165 ! genitalia development GO:0048806 30 17 0,000 0,01513574 0,02566355 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01513574 0,02564548 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01513574 0,02562743 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01513574 0,02560941 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01513574 0,02559141 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01513574 0,02557344 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01513574 0,0255555 ! steroid catabolic process GO:0006706 31 17 0,000 0,01513574 0,02553758 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01513574 0,02551968 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01513574 0,02550181 ! gas transport GO:0015669 25 17 0,000 0,01513574 0,02548396 ! organic cation transport GO:0015695 31 17 0,000 0,01513574 0,02546614 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01513574 0,02544835 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01513574 0,02543057 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01513574 0,02541283 ! microspike assembly GO:0030035 36 17 0,000 0,01513574 0,02539511 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01513574 0,02537741 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01513574 0,02535974 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01601917 0,02682124 ! neuron maturation GO:0042551 42 18 0,000 0,01601917 0,02680259 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01601917 0,02678396 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01601917 0,02676536 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01601917 0,02674679 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01601917 0,02672824 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01601917 0,02670972 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01601917 0,02669122 ! memory GO:0007613 31 18 0,000 0,01601917 0,02667275 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01601917 0,0266543 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01601917 0,02663588 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01601917 0,02661749 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01601917 0,02659912 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01601917 0,02658077 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01601917 0,02656246 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01601917 0,02654416 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01601917 0,02652589 ! response to retinoic acid GO:0032526 26 18 0,000 0,01601917 0,02650765 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01601917 0,02648943 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01601917 0,02647124 ! response to fungus GO:0009620 21 18 0,000 0,01601917 0,02645307 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01601917 0,02643493 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01601917 0,02641681 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01601917 0,02639871 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01601917 0,02638064 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01601917 0,0263626 ! vitamin transport GO:0051180 27 18 0,000 0,01601917 0,02634458 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01601917 0,02632659 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01601917 0,02630862 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01601917 0,02629067 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01601917 0,02627275 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01601917 0,02625485 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01601917 0,02623698 ! nerve development GO:0021675 28 18 0,000 0,01601917 0,02621913 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01601917 0,02620131 ! protein secretion GO:0009306 39 19 0,000 0,01690184 0,02762624 ! positive regulation of translation GO:0045727 30 19 0,000 0,01690184 0,02760749 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01690184 0,02758876 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01690184 0,02757005 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01690184 0,02755137 ! skin development GO:0043588 36 19 0,000 0,01690184 0,02753272 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01690184 0,02751409 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01690184 0,02749549 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01690184 0,02747691 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01690184 0,02745836 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01690184 0,02743983 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01690184 0,02742133 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01690184 0,02740285 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01690184 0,02738439 ! cerebral cortex development GO:0021987 36 19 0,000 0,01690184 0,02736597 ! pigmentation during development GO:0048066 41 19 0,000 0,01690184 0,02734756 ! response to vitamin A GO:0033189 27 19 0,000 0,01690184 0,02732918 ! heme metabolic process GO:0042168 36 19 0,000 0,01690184 0,02731083 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01690184 0,0272925 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01690184 0,0272742 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01690184 0,02725592 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01690184 0,02723766 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01690184 0,02721943 ! peptide cross-linking GO:0018149 37 19 0,000 0,01690184 0,02720122 ! protein export from nucleus GO:0006611 36 19 0,000 0,01690184 0,02718304 ! heart process GO:0003015 30 19 0,000 0,01690184 0,02716488 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01690184 0,02714675 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01690184 0,02712864 ! visual learning GO:0008542 36 19 0,000 0,01690184 0,02711055 ! cellular pigmentation GO:0033059 36 19 0,000 0,01690184 0,02709249 ! G1 phase GO:0051318 40 19 0,000 0,01690184 0,02707445 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01690184 0,02705644 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01690184 0,02703845 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01690184 0,02702048 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01690184 0,02700254 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01690184 0,02698462 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01690184 0,02696673 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01690184 0,02694886 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01690184 0,02693101 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01690184 0,02691319 ! cilium assembly GO:0042384 37 19 0,000 0,01690184 0,02689539 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01690184 0,02687761 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01778375 0,02826136 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01778375 0,0282427 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01778375 0,02822407 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01778375 0,02820547 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01778375 0,02818689 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01778375 0,02816833 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01778375 0,0281498 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01778375 0,02813129 ! response to vitamin GO:0033273 31 20 0,000 0,01778375 0,02811281 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01778375 0,02809435 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01778375 0,02807592 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01778375 0,02805751 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01778375 0,02803912 ! response to alkaloid GO:0043279 38 20 0,000 0,01778375 0,02802076 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01778375 0,02800242 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01778375 0,0279841 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01778375 0,02796581 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01778375 0,02794755 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01778375 0,02792931 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01778375 0,02791109 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01778375 0,02789289 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01778375 0,02787472 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01778375 0,02785657 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01778375 0,02783845 ! body fluid secretion GO:0007589 31 20 0,000 0,01778375 0,02782035 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01778375 0,02780227 ! peptide secretion GO:0002790 35 20 0,000 0,01778375 0,02778422 ! stem cell differentiation GO:0048863 53 20 0,000 0,01778375 0,02776619 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01778375 0,02774818 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01778375 0,0277302 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01778375 0,02771224 ! sensory perception of pain GO:0019233 30 20 0,000 0,01778375 0,0276943 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01778375 0,02767639 ! diencephalon development GO:0021536 34 20 0,000 0,01778375 0,0276585 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01778375 0,02764063 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01778375 0,02762279 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01778375 0,02760496 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01778375 0,02758717 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01778375 0,02756939 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01778375 0,02755164 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01778375 0,02753391 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01778375 0,0275162 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01778375 0,02749852 ! regulation of glucose import GO:0046324 29 20 0,000 0,01778375 0,02748086 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01778375 0,02746322 ! actin filament-based movement GO:0030048 43 20 0,000 0,01778375 0,0274456 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01778375 0,02742801 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01778375 0,02741044 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01778375 0,02739289 ! negative regulation of translation GO:0017148 29 20 0,000 0,01778375 0,02737536 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01778375 0,02735786 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01778375 0,02734038 ! regulation of cell killing GO:0031341 42 21 0,000 0,01866489 0,02867671 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01866489 0,02865841 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01866489 0,02864014 ! hormone secretion GO:0046879 38 21 0,000 0,01866489 0,02862188 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01866489 0,02860365 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01866489 0,02858544 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01866489 0,02856726 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01866489 0,0285491 ! axis specification GO:0009798 38 21 0,000 0,01866489 0,02853096 ! ovarian follicle development GO:0001541 35 21 0,000 0,01866489 0,02851285 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01866489 0,02849475 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01866489 0,02847668 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01866489 0,02845864 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01866489 0,02844062 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01866489 0,02842262 ! cell aging GO:0007569 44 21 0,000 0,01866489 0,02840464 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01866489 0,02838668 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01866489 0,02836875 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01866489 0,02835084 ! cytolysis GO:0019835 24 21 0,000 0,01866489 0,02833295 ! vasodilation GO:0042311 39 21 0,000 0,01866489 0,02831509 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01866489 0,02829725 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01866489 0,02827943 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01866489 0,02826163 ! oogenesis GO:0048477 36 21 0,000 0,01866489 0,02824386 ! DNA modification GO:0006304 34 21 0,000 0,01866489 0,0282261 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01866489 0,02820837 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01866489 0,02819067 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01866489 0,02817298 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01866489 0,02815532 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01866489 0,02813768 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01866489 0,02812006 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01866489 0,02810246 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01866489 0,02808489 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01866489 0,02806733 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01866489 0,0280498 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01866489 0,02803229 ! collagen catabolic process GO:0030574 28 21 0,000 0,01866489 0,0280148 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01866489 0,02799734 ! gut development GO:0048565 39 21 0,000 0,01866489 0,0279799 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01954528 0,02928141 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01954528 0,02926318 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01954528 0,02924499 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01954528 0,02922681 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01954528 0,02920866 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01954528 0,02919053 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01954528 0,02917242 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01954528 0,02915433 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01954528 0,02913627 ! regeneration GO:0031099 41 22 0,000 0,01954528 0,02911823 ! keratinization GO:0031424 28 22 0,000 0,01954528 0,02910021 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01954528 0,02908221 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01954528 0,02906424 ! sensory perception of taste GO:0050909 28 22 0,000 0,01954528 0,02904629 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01954528 0,02902836 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01954528 0,02901045 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01954528 0,02899256 ! vacuolar transport GO:0007034 36 22 0,000 0,01954528 0,0289747 ! lysosome organization GO:0007040 41 22 0,000 0,01954528 0,02895686 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01954528 0,02893904 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01954528 0,02892124 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01954528 0,02890346 ! fucose metabolic process GO:0006004 39 22 0,000 0,01954528 0,02888571 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01954528 0,02886798 ! ureteric bud development GO:0001657 43 22 0,000 0,01954528 0,02885027 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01954528 0,02883258 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01954528 0,02881491 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01954528 0,02879727 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01954528 0,02877964 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01954528 0,02876204 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01954528 0,02874446 ! sarcomere organization GO:0045214 30 22 0,000 0,01954528 0,0287269 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01954528 0,02870936 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01954528 0,02869185 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01954528 0,02867435 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01954528 0,02865688 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01954528 0,02863943 ! protein stabilization GO:0050821 39 22 0,000 0,01954528 0,02862199 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0204249 0,02989192 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0204249 0,02987375 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0204249 0,0298556 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0204249 0,02983747 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0204249 0,02981936 ! gluconeogenesis GO:0006094 33 23 0,000 0,0204249 0,02980128 ! viral genome replication GO:0019079 41 23 0,000 0,0204249 0,02978322 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0204249 0,02976518 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0204249 0,02974716 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0204249 0,02972917 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0204249 0,02971119 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0204249 0,02969324 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0204249 0,02967531 ! visual behavior GO:0007632 42 23 0,000 0,0204249 0,0296574 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0204249 0,02963951 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0204249 0,02962165 ! response to ethanol GO:0045471 46 23 0,000 0,0204249 0,0296038 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0204249 0,02958598 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0204249 0,02956818 ! peroxisome organization GO:0007031 37 23 0,000 0,0204249 0,0295504 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0204249 0,02953264 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0204249 0,0295149 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0204249 0,02949719 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0204249 0,02947949 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0204249 0,02946182 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0204249 0,02944416 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0204249 0,02942653 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0204249 0,02940892 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0204249 0,02939133 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0204249 0,02937377 ! fatty acid transport GO:0015908 44 23 0,000 0,0204249 0,02935622 ! platelet activation GO:0030168 37 23 0,000 0,0204249 0,02933869 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0204249 0,02932119 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0204249 0,0293037 ! hormone transport GO:0009914 40 23 0,000 0,0204249 0,02928624 ! cell-cell recognition GO:0009988 25 23 0,000 0,0204249 0,0292688 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0204249 0,02925138 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0204249 0,02923397 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0204249 0,02921659 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0204249 0,02919923 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0204249 0,0291819 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,02130376 0,0304195 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02130376 0,03040146 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,02130376 0,03038344 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02130376 0,03036544 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02130376 0,03034746 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02130376 0,0303295 ! vesicle docking GO:0048278 47 24 0,000 0,02130376 0,03031157 ! spinal cord development GO:0021510 47 24 0,000 0,02130376 0,03029365 ! vacuole organization GO:0007033 43 24 0,000 0,02130376 0,03027576 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02130376 0,03025789 ! digestive system process GO:0022600 39 24 0,000 0,02130376 0,03024003 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02130376 0,0302222 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02130376 0,03020439 ! regulation of behavior GO:0050795 43 24 0,000 0,02130376 0,03018661 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02130376 0,03016884 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02130376 0,03015109 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02130376 0,03013337 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02130376 0,03011566 ! membrane depolarization GO:0051899 39 24 0,000 0,02130376 0,03009798 ! pallium development GO:0021543 49 24 0,000 0,02130376 0,03008032 ! pentose metabolic process GO:0019321 35 24 0,000 0,02130376 0,03006267 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,02130376 0,03004505 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,02130376 0,03002745 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02130376 0,03000987 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02130376 0,02999231 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02130376 0,02997477 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02130376 0,02995725 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02130376 0,02993975 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02130376 0,02992228 ! regulation of amine transport GO:0051952 40 24 0,000 0,02130376 0,02990482 ! protein tetramerization GO:0051262 52 24 0,000 0,02130376 0,02988738 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02218187 0,03110115 ! myelination GO:0042552 45 25 0,000 0,02218187 0,03108304 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02218187 0,03106495 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02218187 0,03104687 ! phototransduction GO:0007602 33 25 0,000 0,02218187 0,03102882 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02218187 0,03101079 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,02218187 0,03099279 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02218187 0,0309748 ! sperm motility GO:0030317 31 25 0,000 0,02218187 0,03095683 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02218187 0,03093889 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02218187 0,03092096 ! receptor metabolic process GO:0043112 46 25 0,000 0,02218187 0,03090306 ! response to starvation GO:0042594 42 25 0,000 0,02218187 0,03088517 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02218187 0,03086731 ! neural crest cell development GO:0014032 54 25 0,000 0,02218187 0,03084947 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,02218187 0,03083164 ! negative regulation of cell development GO:0010721 73 25 0,000 0,02218187 0,03081384 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02218187 0,03079606 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02218187 0,0307783 ! interaction with host GO:0051701 62 25 0,000 0,02218187 0,03076056 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02218187 0,03074284 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02218187 0,03072515 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02218187 0,03070747 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02218187 0,03068981 ! immunoglobulin production GO:0002377 55 25 0,000 0,02218187 0,03067217 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02218187 0,03065455 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02218187 0,03063696 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02218187 0,03061938 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02218187 0,03060182 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02218187 0,03058428 ! telomere organization GO:0032200 43 25 0,000 0,02218187 0,03056677 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02218187 0,03054927 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,02218187 0,03053179 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02305921 0,03172125 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02305921 0,03170313 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02305921 0,03168502 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02305921 0,03166694 ! initiation of viral infection GO:0019059 57 26 0,000 0,02305921 0,03164887 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02305921 0,03163083 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02305921 0,0316128 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02305921 0,0315948 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02305921 0,03157682 ! molting cycle process GO:0022404 50 26 0,000 0,02305921 0,03155886 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02305921 0,03154092 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02305921 0,03152299 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02305921 0,03150509 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02305921 0,03148721 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02305921 0,03146935 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02305921 0,03145151 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,02305921 0,03143369 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02305921 0,0314159 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02305921 0,03139812 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02305921 0,03138036 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02305921 0,03136262 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02305921 0,0313449 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02305921 0,0313272 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02305921 0,03130952 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02305921 0,03129186 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02305921 0,03127422 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02305921 0,0312566 ! blastocyst development GO:0001824 49 26 0,000 0,02305921 0,031239 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02305921 0,03122142 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02305921 0,03120386 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02305921 0,03118632 ! neuron fate commitment GO:0048663 48 27 0,000 0,0239358 0,03235367 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0239358 0,03233551 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0239358 0,03231736 ! iron ion transport GO:0006826 59 27 0,000 0,0239358 0,03229924 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0239358 0,03228113 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0239358 0,03226305 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0239358 0,03224498 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0239358 0,03222694 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0239358 0,03220892 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0239358 0,03219091 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0239358 0,03217293 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0239358 0,03215496 ! autophagy GO:0006914 41 27 0,000 0,0239358 0,03213702 ! male gonad development GO:0008584 44 27 0,000 0,0239358 0,0321191 ! response to toxin GO:0009636 47 27 0,000 0,0239358 0,03210119 ! primary neural tube formation GO:0014020 51 27 0,000 0,0239358 0,03208331 ! base-excision repair GO:0006284 41 27 0,000 0,0239358 0,03206545 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0239358 0,0320476 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0239358 0,03202978 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0239358 0,03201197 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0239358 0,03199419 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0239358 0,03197642 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0239358 0,03195868 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0239358 0,03194095 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0239358 0,03192325 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02481163 0,03307301 ! circadian rhythm GO:0007623 50 28 0,000 0,02481163 0,0330547 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02481163 0,03303641 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02481163 0,03301814 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,02481163 0,03299988 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02481163 0,03298165 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02481163 0,03296344 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02481163 0,03294525 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02481163 0,03292708 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02481163 0,03290892 ! synaptogenesis GO:0007416 42 28 0,000 0,02481163 0,03289079 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02481163 0,03287268 ! lipid oxidation GO:0034440 43 28 0,000 0,02481163 0,03285459 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02481163 0,03283652 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02481163 0,03281847 ! translational initiation GO:0006413 65 29 0,000 0,02568671 0,03395726 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02568671 0,03393861 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02568671 0,03391999 ! regulation of pH GO:0006885 43 29 0,000 0,02568671 0,03390138 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02568671 0,03388279 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02568671 0,03386423 ! catechol metabolic process GO:0009712 54 29 0,000 0,02568671 0,03384568 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02568671 0,03382716 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02568671 0,03380865 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02568671 0,03379017 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02568671 0,0337717 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02568671 0,03375326 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02568671 0,03373483 ! cell fate determination GO:0001709 60 29 0,000 0,02568671 0,03371643 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02568671 0,03369805 ! detection of light stimulus GO:0009583 38 29 0,000 0,02568671 0,03367968 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02568671 0,03366134 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02568671 0,03364301 ! tissue homeostasis GO:0001894 48 29 0,000 0,02568671 0,03362471 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02568671 0,03360642 ! phenol metabolic process GO:0018958 55 30 0,000 0,02656102 0,03473143 ! zinc ion transport GO:0006829 45 30 0,000 0,02656102 0,03471256 ! membrane docking GO:0022406 61 30 0,000 0,02656102 0,03469371 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02656102 0,03467489 ! cell junction assembly GO:0034329 78 30 0,000 0,02656102 0,03465609 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02656102 0,0346373 ! acute-phase response GO:0006953 49 30 0,000 0,02656102 0,03461854 ! myofibril assembly GO:0030239 47 30 0,000 0,02656102 0,0345998 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02656102 0,03458107 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02656102 0,03456237 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02656102 0,03454369 ! phospholipid transport GO:0015914 51 30 0,000 0,02656102 0,03452503 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02656102 0,03450638 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02656102 0,03448776 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02656102 0,03446916 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02656102 0,03445058 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02656102 0,03443202 ! eye morphogenesis GO:0048592 60 30 0,000 0,02656102 0,03441347 ! response to heat GO:0009408 50 30 0,000 0,02656102 0,03439495 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02743459 0,03550705 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02743459 0,03548796 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02743459 0,03546889 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02743459 0,03544985 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02743459 0,03543082 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02743459 0,03541181 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02743459 0,03539282 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02743459 0,03537385 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02743459 0,03535491 ! ovulation cycle process GO:0022602 49 31 0,000 0,02743459 0,03533598 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02743459 0,03531707 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02743459 0,03529819 ! peptide transport GO:0015833 55 31 0,000 0,02743459 0,03527932 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02743459 0,03526048 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02743459 0,03524165 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02743459 0,03522285 ! mesoderm formation GO:0001707 69 31 0,000 0,02743459 0,03520406 ! natural killer cell activation GO:0030101 45 31 0,000 0,02743459 0,03518529 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02743459 0,03516655 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02743459 0,03514782 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02743459 0,03512912 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02743459 0,03511043 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02830739 0,03620818 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02830739 0,03618894 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02830739 0,03616972 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02830739 0,03615052 ! cholesterol transport GO:0030301 56 32 0,000 0,02830739 0,03613135 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02830739 0,03611219 ! spliceosome assembly GO:0000245 67 32 0,000 0,02830739 0,03609305 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02830739 0,03607393 ! metanephros development GO:0001656 74 32 0,000 0,02830739 0,03605484 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02830739 0,03603576 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02830739 0,0360167 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02830739 0,03599767 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02830739 0,03597865 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02830739 0,03595965 ! muscle cell development GO:0055001 49 32 0,000 0,02830739 0,03594068 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02830739 0,03592172 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02830739 0,03590279 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02830739 0,03588387 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02830739 0,03586497 ! ovulation cycle GO:0042698 51 32 0,000 0,02830739 0,0358461 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02830739 0,03582724 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02830739 0,0358084 ! hindbrain development GO:0030902 61 32 0,000 0,02830739 0,03578959 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02830739 0,03577079 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02830739 0,03575201 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02830739 0,03573326 ! gene silencing GO:0016458 65 32 0,000 0,02830739 0,03571452 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02917944 0,03679546 ! post-embryonic development GO:0009791 69 33 0,000 0,02917944 0,03677619 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02917944 0,03675693 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02917944 0,0367377 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02917944 0,03671849 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02917944 0,03669929 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02917944 0,03668012 ! cell fate specification GO:0001708 52 33 0,000 0,02917944 0,03666096 ! sterol transport GO:0015918 57 33 0,000 0,02917944 0,03664183 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02917944 0,03662271 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02917944 0,03660362 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02917944 0,03658455 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02917944 0,03656549 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03005074 0,03763774 ! glial cell differentiation GO:0010001 63 34 0,000 0,03005074 0,03761815 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03005074 0,03759859 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03005074 0,03757905 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03005074 0,03755953 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03005074 0,03754003 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,03005074 0,03752054 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03005074 0,03750108 ! mismatch repair GO:0006298 46 34 0,000 0,03005074 0,03748164 ! spermatid development GO:0007286 63 34 0,000 0,03005074 0,03746222 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03005074 0,03744282 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03005074 0,03742344 ! placenta development GO:0001890 53 34 0,000 0,03005074 0,03740408 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,03005074 0,03738474 ! regulation of muscle development GO:0048634 70 35 0,000 0,03092129 0,03844787 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03092129 0,03842801 ! negative regulation of secretion GO:0051048 63 35 0,000 0,03092129 0,03840817 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03092129 0,03838835 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03092129 0,03836855 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,03092129 0,03834877 ! odontogenesis GO:0042476 66 35 0,000 0,03092129 0,03832902 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03092129 0,03830928 ! female gonad development GO:0008585 58 35 0,000 0,03092129 0,03828956 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03092129 0,03826987 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03092129 0,03825019 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,03092129 0,03823054 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03092129 0,0382109 ! cytokine production GO:0001816 59 35 0,000 0,03092129 0,03819128 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,03092129 0,03817169 ! neural tube formation GO:0001841 67 35 0,000 0,03092129 0,03815211 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03179108 0,0392052 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03179108 0,03918512 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03179108 0,03916505 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03179108 0,03914501 ! cell junction organization GO:0034330 86 36 0,000 0,03179108 0,03912498 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03179108 0,03910498 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03179108 0,039085 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03179108 0,03906504 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03179108 0,0390451 ! regulation of proteolysis GO:0030162 72 36 0,000 0,03179108 0,03902518 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03179108 0,03900528 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03179108 0,0389854 ! aerobic respiration GO:0009060 55 36 0,000 0,03179108 0,03896554 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03179108 0,0389457 ! embryonic organ development GO:0048568 57 36 0,000 0,03179108 0,03892588 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03179108 0,03890608 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03179108 0,0388863 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03266012 0,03992899 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03266012 0,03990871 ! meiosis I GO:0007127 65 37 0,000 0,03266012 0,03988846 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,03266012 0,03986822 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03266012 0,039848 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03266012 0,03982781 ! organic anion transport GO:0015711 68 37 0,000 0,03266012 0,03980763 ! tissue remodeling GO:0048771 76 37 0,000 0,03266012 0,03978747 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03266012 0,03976734 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03266012 0,03974722 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03266012 0,03972713 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03266012 0,03970705 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03266012 0,039687 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03266012 0,03966697 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03266012 0,03964695 ! pigment metabolic process GO:0042440 80 37 0,000 0,03266012 0,03962696 ! spermatid differentiation GO:0048515 66 37 0,000 0,03266012 0,03960699 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03266012 0,03958703 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03352841 0,04061902 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,03352841 0,04059857 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03352841 0,04057815 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03352841 0,04055775 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03352841 0,04053737 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03352841 0,04051701 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03352841 0,04049667 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03352841 0,04047635 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,03352841 0,04045605 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03352841 0,04043577 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03352841 0,04041551 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03352841 0,04039528 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03352841 0,04037506 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03352841 0,04035486 ! glucan metabolic process GO:0044042 62 38 0,000 0,03352841 0,04033468 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03439595 0,04135765 ! mammary gland development GO:0030879 86 39 0,000 0,03439595 0,041337 ! learning GO:0007612 77 39 0,000 0,03439595 0,04131636 ! ear morphogenesis GO:0042471 60 39 0,000 0,03439595 0,04129574 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03439595 0,04127515 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03439595 0,04125457 ! segmentation GO:0035282 67 39 0,000 0,03439595 0,04123401 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03439595 0,04121348 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03439595 0,04119297 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03439595 0,04117247 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03439595 0,041152 ! RNA modification GO:0009451 57 39 0,000 0,03439595 0,04113154 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03439595 0,04111111 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03526274 0,0421262 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03526274 0,04210529 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03526274 0,04208441 ! feeding behavior GO:0007631 59 40 0,000 0,03526274 0,04206354 ! negative regulation of binding GO:0051100 72 40 0,000 0,03526274 0,0420427 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03526274 0,04202187 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03526274 0,04200107 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03526274 0,04198029 ! maintenance of protein location GO:0045185 91 40 0,000 0,03526274 0,04195953 ! cytokinesis GO:0000910 72 40 0,000 0,03526274 0,04193879 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03612879 0,04294756 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03612879 0,04292635 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03612879 0,04290516 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03612879 0,042884 ! gliogenesis GO:0042063 88 41 0,000 0,03612879 0,04286285 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03612879 0,04284172 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03612879 0,04282062 ! T cell differentiation GO:0030217 81 41 0,000 0,03612879 0,04279954 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,03612879 0,04277847 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03612879 0,04275743 ! female gamete generation GO:0007292 61 41 0,000 0,03612879 0,04273641 ! polyol metabolic process GO:0019751 66 41 0,000 0,03612879 0,04271541 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03612879 0,04269443 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03699408 0,04369551 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03699408 0,04367407 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03699408 0,04365265 ! regulation of tube size GO:0035150 71 42 0,000 0,03699408 0,04363125 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03699408 0,04360987 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03699408 0,04358852 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03699408 0,04356718 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03699408 0,04354587 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03699408 0,04352457 ! neuron migration GO:0001764 79 42 0,000 0,03699408 0,0435033 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03699408 0,04348205 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03699408 0,04346082 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03785862 0,04445478 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,03785862 0,04443309 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03785862 0,04441143 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03785862 0,04438979 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03785862 0,04436817 ! glucose transport GO:0015758 65 43 0,000 0,03785862 0,04434656 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,03785862 0,04432498 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,03785862 0,04430343 ! neural tube development GO:0021915 77 43 0,000 0,03785862 0,04428189 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03785862 0,04426037 ! striated muscle contraction GO:0006941 77 43 0,000 0,03785862 0,04423887 ! phagocytosis GO:0006909 90 43 0,000 0,03785862 0,0442174 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03785862 0,04419595 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03872242 0,04518241 ! hexose transport GO:0008645 67 44 0,000 0,03872242 0,04516051 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03872242 0,04513863 ! male sex differentiation GO:0046661 76 44 0,000 0,03872242 0,04511677 ! double-strand break repair GO:0006302 81 44 0,000 0,03872242 0,04509494 ! biopolymer methylation GO:0043414 84 44 0,000 0,03872242 0,04507312 ! B cell differentiation GO:0030183 107 44 0,000 0,03872242 0,04505132 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03872242 0,04502955 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03872242 0,0450078 ! developmental growth GO:0048589 82 44 0,000 0,03872242 0,04498606 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03872242 0,04496435 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03958547 0,04594435 ! glycolysis GO:0006096 65 45 0,000 0,03958547 0,0459222 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03958547 0,04590007 ! leukocyte migration GO:0050900 68 45 0,000 0,03958547 0,04587796 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03958547 0,04585587 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03958547 0,0458338 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03958547 0,04581175 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03958547 0,04578973 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03958547 0,04576772 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03958547 0,04574574 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03958547 0,04572378 ! cell growth GO:0016049 84 45 0,000 0,03958547 0,04570184 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,04044777 0,04667498 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,04044777 0,04665261 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,04044777 0,04663025 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,04044777 0,04660792 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,04044777 0,04658561 ! pigmentation GO:0043473 100 46 0,000 0,04044777 0,04656332 ! response to insulin stimulus GO:0032868 95 46 0,000 0,04044777 0,04654105 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,04044777 0,0465188 ! positive regulation of defense response GO:0031349 76 47 0,000 0,04130933 0,04748698 ! endosome transport GO:0016197 108 47 0,000 0,04130933 0,0474643 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,04130933 0,04744165 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,04130933 0,04741901 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,04130933 0,0473964 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,04130933 0,04737381 ! JNK cascade GO:0007254 91 47 0,000 0,04130933 0,04735124 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,04130933 0,04732869 ! methylation GO:0032259 90 47 0,000 0,04130933 0,04730616 ! protein homooligomerization GO:0051260 76 47 0,000 0,04130933 0,04728366 ! mitochondrial transport GO:0006839 82 48 0,000 0,04217014 0,04824601 ! Notch signaling pathway GO:0007219 96 48 0,000 0,04217014 0,04822308 ! cellular component disassembly GO:0022411 86 48 0,000 0,04217014 0,04820017 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,04217014 0,04817729 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,04217014 0,04815442 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,04217014 0,04813158 ! activation of caspase activity GO:0006919 84 48 0,000 0,04217014 0,04810875 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,04217014 0,04808595 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,04217014 0,04806318 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,04217014 0,04804042 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,04303021 0,04899701 ! regulation of action potential GO:0001508 95 49 0,000 0,04303021 0,04897384 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,04303021 0,04895068 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,04303021 0,04892755 ! regulation of ion transport GO:0043269 77 49 0,000 0,04303021 0,04890443 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,04303021 0,04888134 ! peptide metabolic process GO:0006518 76 49 0,000 0,04303021 0,04885828 ! response to temperature stimulus GO:0009266 76 49 0,000 0,04303021 0,04883523 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,04303021 0,04881221 ! endocrine system development GO:0035270 104 49 0,000 0,04303021 0,0487892 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,04303021 0,04876622 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,04303021 0,04874326 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,04303021 0,04872032 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,04303021 0,04869741 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04388954 0,04964656 ! neuromuscular process GO:0050905 99 50 0,000 0,04388954 0,04962323 ! regulation of ossification GO:0030278 117 50 0,000 0,04388954 0,04959992 ! inner ear development GO:0048839 79 50 0,000 0,04388954 0,04957663 ! histone modification GO:0016570 91 50 0,000 0,04388954 0,04955337 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04388954 0,04953012 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04388954 0,0495069 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04388954 0,0494837 ! positive regulation of binding GO:0051099 78 51 0,000 0,04474812 0,05042809 ! viral infectious cycle GO:0019058 99 51 0,000 0,04474812 0,05040448 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04474812 0,05038089 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04474812 0,05035733 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04474812 0,05033379 ! excretion GO:0007588 83 51 0,000 0,04474812 0,05031027 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04474812 0,05028677 ! chromatin remodeling GO:0006338 109 51 0,000 0,04474812 0,05026329 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04474812 0,05023984 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04474812 0,0502164 ! vesicle organization GO:0016050 107 51 0,000 0,04474812 0,05019299 ! regulation of cell shape GO:0008360 125 51 0,000 0,04474812 0,0501696 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04474812 0,05014624 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04560596 0,05108377 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04560596 0,05106 ! membrane fusion GO:0006944 110 52 0,000 0,04560596 0,05103625 ! positive regulation of growth GO:0045927 90 52 0,000 0,04560596 0,05101252 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04560596 0,05098882 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04560596 0,05096513 ! amino acid activation GO:0043038 92 52 0,000 0,04560596 0,05094147 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04560596 0,05091783 ! synapse organization GO:0050808 85 52 0,000 0,04560596 0,05089422 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04646306 0,05182666 ! RNA catabolic process GO:0006401 93 53 0,000 0,04646306 0,05180265 ! regulation of translational initiation GO:0006446 82 53 0,000 0,04646306 0,05177865 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04646306 0,05175468 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04646306 0,05173073 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04646306 0,0517068 ! cell maturation GO:0048469 100 53 0,000 0,04646306 0,0516829 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,04646306 0,05165902 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04646306 0,05163515 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04731941 0,05256256 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04731941 0,0525383 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04731941 0,05251407 ! cell recognition GO:0008037 85 54 0,000 0,04731941 0,05248986 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04731941 0,05246567 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04731941 0,0524415 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04731941 0,05241736 ! chloride transport GO:0006821 90 55 0,000 0,04817503 0,0533406 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04817503 0,05331606 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04817503 0,05329155 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04817503 0,05326706 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04817503 0,05324259 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04817503 0,05321814 ! aging GO:0007568 103 55 0,000 0,04817503 0,05319372 ! gastrulation GO:0007369 112 55 0,000 0,04817503 0,05316932 ! heart morphogenesis GO:0003007 97 55 0,000 0,04817503 0,05314494 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04817503 0,05312058 ! RNA elongation GO:0006354 79 55 0,000 0,04817503 0,05309625 ! nuclear export GO:0051168 97 55 0,000 0,04817503 0,05307194 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04817503 0,05304765 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0490299 0,05396429 ! sensory perception of smell GO:0007608 80 56 0,000 0,0490299 0,05393962 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0490299 0,05391497 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0490299 0,05389034 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0490299 0,05386573 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0490299 0,05384114 ! proton transport GO:0015992 94 56 0,000 0,0490299 0,05381658 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0490299 0,05379204 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04988404 0,05470419 ! muscle fiber development GO:0048747 112 57 0,000 0,04988404 0,05467927 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04988404 0,05465437 ! lipid modification GO:0030258 97 57 0,000 0,04988404 0,05462949 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04988404 0,05460464 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04988404 0,05457981 ! maintenance of location GO:0051235 118 57 0,000 0,04988404 0,054555 ! hydrogen transport GO:0006818 97 58 0,000 0,05073744 0,0554631 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,05073744 0,05543791 ! regulation of endocytosis GO:0030100 91 58 0,000 0,05073744 0,05541274 ! adult behavior GO:0030534 99 58 0,000 0,05073744 0,0553876 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,05073744 0,05536248 ! positive regulation of secretion GO:0051047 95 59 0,000 0,0515901 0,05626735 ! regulation of cellular component size GO:0032535 109 59 0,000 0,0515901 0,05624185 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,0515901 0,05621638 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,0515901 0,05619093 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,0515901 0,05616551 ! DNA catabolic process GO:0006308 86 59 0,000 0,0515901 0,0561401 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,0515901 0,05611472 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,05244202 0,05701559 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,05244202 0,05698984 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,05244202 0,05696411 ! regulation of heart contraction GO:0008016 110 60 0,000 0,05244202 0,0569384 ! camera-type eye development GO:0043010 116 60 0,000 0,05244202 0,05691272 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,05244202 0,05688706 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,05244202 0,05686142 ! kidney development GO:0001822 122 60 0,000 0,05244202 0,05683581 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,0532932 0,0577323 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,0532932 0,05770632 ! mesoderm development GO:0007498 119 61 0,000 0,0532932 0,05768036 ! tRNA processing GO:0008033 89 61 0,000 0,0532932 0,05765443 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,0532932 0,05762852 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,0532932 0,05760263 ! ear development GO:0043583 103 62 0,000 0,05414365 0,05849557 ! viral reproductive process GO:0022415 126 62 0,000 0,05414365 0,05846931 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05414365 0,05844308 ! gonad development GO:0008406 98 62 0,000 0,05414365 0,05841687 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05414365 0,05839069 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05499336 0,05928048 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,05499336 0,05925393 ! detection of external stimulus GO:0009581 91 63 0,000 0,05499336 0,05922741 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05499336 0,05920091 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05499336 0,05917443 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05584234 0,0600611 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05584234 0,06003426 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05584234 0,06000745 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05584234 0,05998066 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,05584234 0,05995389 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,05669059 0,06083744 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,05669059 0,06081032 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,05669059 0,06078322 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,05669059 0,06075615 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,05669059 0,0607291 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,0575381 0,06160955 ! actin filament organization GO:0007015 148 66 0,000 0,0575381 0,06158214 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,0575381 0,06155476 ! extracellular matrix organization GO:0030198 133 66 0,000 0,0575381 0,0615274 ! secondary metabolic process GO:0019748 116 66 0,000 0,0575381 0,06150007 ! developmental maturation GO:0021700 116 66 0,000 0,0575381 0,06147276 ! cell projection assembly GO:0030031 120 66 0,000 0,0575381 0,06144548 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,05838487 0,06232209 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05838487 0,06229446 ! activation of MAPK activity GO:0000187 115 67 0,000 0,05838487 0,06226684 ! lung development GO:0030324 144 67 0,000 0,05838487 0,06223926 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05838487 0,06221169 ! hexose catabolic process GO:0019320 104 67 0,000 0,05838487 0,06218415 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,05838487 0,06215664 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05838487 0,06212915 ! adaptive immune response GO:0002250 119 67 0,000 0,05838487 0,06210168 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05838487 0,06207424 ! amino acid transport GO:0006865 125 68 0,000 0,05923091 0,06294593 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05923091 0,06291814 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05923091 0,06289037 ! viral reproduction GO:0016032 134 68 0,000 0,05923091 0,06286263 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05923091 0,06283491 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05923091 0,06280722 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,06007623 0,06367551 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,06007623 0,06364747 ! urogenital system development GO:0001655 137 69 0,000 0,06007623 0,06361945 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,06007623 0,06359147 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,06007623 0,0635635 ! antigen processing and presentation GO:0019882 104 69 0,000 0,06007623 0,06353556 ! appendage morphogenesis GO:0035107 135 70 0,000 0,06092081 0,06440047 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,06092081 0,06437218 ! amine catabolic process GO:0009310 117 71 0,000 0,06176466 0,06523519 ! reproductive structure development GO:0048608 113 71 0,000 0,06176466 0,06520656 ! appendage development GO:0048736 136 71 0,000 0,06176466 0,06517797 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,06176466 0,06514939 ! B cell activation GO:0042113 160 71 0,000 0,06176466 0,06512084 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,06176466 0,06509232 ! regulation of immune effector process GO:0002697 137 71 0,000 0,06176466 0,06506382 ! acute inflammatory response GO:0002526 113 72 0,000 0,06260777 0,06592311 ! regulation of caspase activity GO:0043281 122 72 0,000 0,06260777 0,06589427 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,06260777 0,06586546 ! carbohydrate transport GO:0008643 110 72 0,000 0,06260777 0,06583667 ! respiratory system development GO:0060541 153 72 0,000 0,06260777 0,06580791 ! learning or memory GO:0007611 147 73 0,000 0,06345016 0,06666423 ! regulation of blood pressure GO:0008217 125 73 0,000 0,06345016 0,06663514 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,06345016 0,06660606 ! axon guidance GO:0007411 139 73 0,000 0,06345016 0,06657701 ! fertilization GO:0009566 90 73 0,000 0,06345016 0,06654799 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,06429182 0,06740136 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,06429182 0,06737201 ! neurotransmitter transport GO:0006836 123 74 0,000 0,06429182 0,06734268 ! meiosis GO:0007126 121 74 0,000 0,06429182 0,06731337 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,06429182 0,06728409 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,06429182 0,06725484 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,06429182 0,06722561 ! eye development GO:0001654 143 74 0,000 0,06429182 0,06719641 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06513276 0,06804577 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06513276 0,06801624 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06513276 0,06798673 ! meiotic cell cycle GO:0051321 122 75 0,000 0,06513276 0,06795725 ! rhythmic process GO:0048511 128 75 0,000 0,06513276 0,06792779 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06513276 0,06789836 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06597296 0,06874445 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06597296 0,06871469 ! defense response to bacterium GO:0042742 89 76 0,000 0,06597296 0,06868496 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,06597296 0,06865525 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06681244 0,0694988 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,06681244 0,06946877 ! blood coagulation GO:0007596 146 78 0,000 0,06765119 0,07031048 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06765119 0,07028012 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,06765119 0,07024979 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,06765119 0,07021948 ! protein oligomerization GO:0051259 139 78 0,000 0,06765119 0,0701892 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,06848921 0,07102804 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06848921 0,07099743 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06848921 0,07096686 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,06848921 0,07093631 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,06848921 0,07090579 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06932651 0,07174176 ! muscle cell differentiation GO:0042692 159 80 0,000 0,06932651 0,07171091 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06932651 0,0716801 ! protein import into nucleus GO:0006606 158 80 0,000 0,06932651 0,07164931 ! T cell activation GO:0042110 168 81 0,000 0,07016309 0,07248278 ! response to hypoxia GO:0001666 171 81 0,000 0,07016309 0,07245167 ! digestion GO:0007586 112 81 0,000 0,07016309 0,07242059 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,07016309 0,07238953 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,07016309 0,0723585 ! nuclear import GO:0051170 161 81 0,000 0,07016309 0,0723275 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,07016309 0,07229652 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,07099894 0,07312647 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,07099894 0,07309518 ! response to drug GO:0042493 143 82 0,000 0,07099894 0,07306392 ! response to nutrient GO:0007584 125 82 0,000 0,07099894 0,07303268 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,07099894 0,07300147 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,07099894 0,07297029 ! response to oxygen levels GO:0070482 176 83 0,000 0,07183406 0,07379708 ! regulation of lyase activity GO:0051339 160 83 0,000 0,07183406 0,07376558 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,07266847 0,07459058 ! hemostasis GO:0007599 158 84 0,000 0,07266847 0,07455878 ! negative regulation of transport GO:0051051 153 84 0,000 0,07266847 0,074527 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,07266847 0,07449524 ! nucleosome assembly GO:0006334 122 85 0,000 0,07350215 0,07531779 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,07350215 0,07528573 ! amine biosynthetic process GO:0009309 138 86 0,000 0,07433511 0,0761065 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,07433511 0,07607413 ! chromatin assembly GO:0031497 124 86 0,000 0,07433511 0,07604178 ! tube morphogenesis GO:0035239 176 86 0,000 0,07433511 0,07600946 ! mitochondrion organization GO:0007005 148 86 0,000 0,07433511 0,07597717 ! alcohol catabolic process GO:0046164 130 86 0,000 0,07433511 0,07594491 ! amine transport GO:0015837 155 86 0,000 0,07433511 0,07591268 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,07516735 0,07673001 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,07516735 0,07669747 ! protein localization in nucleus GO:0034504 176 87 0,000 0,07516735 0,07666496 ! regulation of protein transport GO:0051223 154 87 0,000 0,07516735 0,07663247 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,07599886 0,07744738 ! regulation of DNA binding GO:0051101 155 88 0,000 0,07599886 0,07741459 ! gland development GO:0048732 206 88 0,000 0,07599886 0,07738183 ! regulation of neurological system process GO:0031644 148 88 0,000 0,07599886 0,0773491 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07599886 0,07731639 ! cellular defense response GO:0006968 114 89 0,000 0,07682966 0,07812856 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07682966 0,07809555 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,07682966 0,07806257 ! ossification GO:0001503 188 90 0,000 0,07765974 0,07887266 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07765974 0,07883938 ! sex differentiation GO:0007548 145 90 0,000 0,07765974 0,07880613 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07765974 0,07877291 ! bone development GO:0060348 189 91 0,000 0,0784891 0,0795806 ! sterol metabolic process GO:0016125 152 91 0,000 0,0784891 0,07954708 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,0784891 0,07951359 ! regulation of defense response GO:0031347 149 92 0,000 0,07931774 0,08031923 ! nucleosome organization GO:0034728 138 92 0,000 0,07931774 0,08028544 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07931774 0,08025168 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07931774 0,08021794 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,08014567 0,08102121 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,08014567 0,08098718 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,08014567 0,08095318 ! regulation of membrane potential GO:0042391 164 93 0,000 0,08014567 0,08091921 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,08014567 0,08088527 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,08097287 0,08168584 ! female pregnancy GO:0007565 164 94 0,000 0,08097287 0,08165161 ! transcription initiation GO:0006352 153 94 0,000 0,08097287 0,0816174 ! regulation of T cell activation GO:0050863 158 94 0,000 0,08097287 0,08158322 ! forebrain development GO:0030900 188 95 0,000 0,08179936 0,08238144 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,08179936 0,08234697 ! leukocyte differentiation GO:0002521 202 96 0,000 0,08262514 0,08314349 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,08262514 0,08310873 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,08262514 0,083074 ! positive regulation of immune response GO:0050778 156 96 0,000 0,08262514 0,0830393 ! detection of stimulus GO:0051606 151 96 0,000 0,08262514 0,08300463 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,0834502 0,08379849 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0834502 0,08376353 ! protein ubiquitination GO:0016567 217 97 0,000 0,0834502 0,0837286 ! hormone metabolic process GO:0042445 157 97 0,000 0,0834502 0,0836937 ! regulation of protein localization GO:0032880 176 97 0,000 0,0834502 0,08365882 ! response to virus GO:0009615 160 98 0,000 0,08427454 0,08445004 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,08427454 0,08441488 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,08427454 0,08437976 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,08509818 0,08516897 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,08509818 0,08513356 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,08509818 0,08509818 GO:0060538|skeletal muscle organ development,