pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5501-6-real-Zhou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL4685_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 6 3,000 1,202E-10 2,853E-07 ! natural killer cell mediated immunity GO:0002228 14 9 3,000 1,006E-09 1,194E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 104 70 5,000 2,287E-09 1,809E-06 ! leukocyte mediated cytotoxicity GO:0001909 18 11 3,000 2,628E-09 1,559E-06 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 108 73 5,000 2,959E-09 1,404E-06 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 110 73 5,000 2,959E-09 1,17E-06 ! positive regulation of ligase activity GO:0051351 114 76 5,000 3,785E-09 1,283E-06 ! regulation of ubiquitin-protein ligase activity GO:0051438 123 79 5,000 4,795E-09 1,422E-06 ! regulation of ligase activity GO:0051340 129 82 5,000 6,018E-09 1,587E-06 ! cell killing GO:0001906 22 14 3,000 7,943E-09 1,885E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 53 4,000 3,384E-08 7,3E-06 ! G2/M transition of mitotic cell cycle GO:0000086 34 21 3,000 4,708E-08 9,31E-06 ! polyol catabolic process GO:0046174 7 5 2,000 4,981E-08 9,092E-06 GO:0019405|alditol catabolic process, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 96 66 4,000 1,037E-07 1,757E-05 ! spindle organization GO:0007051 39 33 3,000 3,171E-07 5,017E-05 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 130 85 4,000 3,715E-07 5,51E-05 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 166 87 4,000 4,175E-07 5,827E-05 ! interphase GO:0051325 169 89 4,000 4,678E-07 6,167E-05 ! microtubule cytoskeleton organization GO:0000226 133 90 4,000 4,947E-07 6,178E-05 ! G1/S transition of mitotic cell cycle GO:0000082 93 44 3,000 1,038E-06 1,231E-04 ! cellular carbohydrate catabolic process GO:0044275 14 12 2,000 1,087E-06 1,228E-04 ! fructose metabolic process GO:0006000 24 17 2,000 3,338E-06 3,601E-04 ! lymphocyte mediated immunity GO:0002449 95 66 3,000 5,36E-06 5,53E-04 ! alditol metabolic process GO:0019400 26 22 2,000 7,515E-06 7,43E-04 ! leukocyte mediated immunity GO:0002443 107 75 3,000 8,938E-06 8,484E-04 ! sperm motility GO:0030317 31 26 2,000 1,263E-05 1,152E-03 ! hexose biosynthetic process GO:0019319 37 31 2,000 2,17E-05 1,907E-03 ! monosaccharide biosynthetic process GO:0046364 40 34 2,000 2,878E-05 2,439E-03 ! establishment of apical/basal cell polarity GO:0035089 7 5 1,000 2,999E-05 2,454E-03 ! polyol metabolic process GO:0019751 47 37 2,000 3,724E-05 2,945E-03 ! alcohol biosynthetic process GO:0046165 48 40 2,000 4,718E-05 3,611E-03 ! induction of apoptosis by intracellular signals GO:0008629 78 42 2,000 5,468E-05 4,055E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,284E-05 4,518E-03 ! eye photoreceptor cell differentiation GO:0001754 14 7 1,000 6,284E-05 4,386E-03 GO:0042462|eye photoreceptor cell development, ! response to UV GO:0009411 79 47 2,000 7,677E-05 5,205E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,369E-05 5,516E-03 ! keratinocyte proliferation GO:0043616 15 8 1,000 8,369E-05 5,367E-03 ! photoreceptor cell development GO:0042461 17 9 1,000 1,075E-04 6,712E-03 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 14 9 1,000 1,075E-04 6,54E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 16 9 1,000 1,075E-04 6,376E-03 ! positive regulation of B cell proliferation GO:0030890 14 10 1,000 1,342E-04 7,767E-03 ! establishment of cell polarity GO:0030010 12 10 1,000 1,342E-04 7,582E-03 ! Golgi vesicle budding GO:0048194 18 11 1,000 1,638E-04 9,042E-03 ! negative regulation of protein kinase activity GO:0006469 110 62 2,000 1,759E-04 9,484E-03 ! negative regulation of kinase activity GO:0033673 112 63 2,000 1,844E-04 9,726E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 23 12 1,000 1,964E-04 0,0101313 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 97 66 2,000 2,118E-04 0,0106915 ! negative regulation of transferase activity GO:0051348 117 66 2,000 2,118E-04 0,01046876 ! negative regulation of ligase activity GO:0051352 100 67 2,000 2,214E-04 0,01072289 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of B cell proliferation GO:0030888 24 13 1,000 2,318E-04 0,01100332 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,702E-04 0,01257158 ! skin development GO:0043588 28 15 1,000 3,114E-04 0,014211 ! release of cytochrome c from mitochondria GO:0001836 29 15 1,000 3,114E-04 0,01394287 ! positive regulation of cell growth GO:0030307 22 16 1,000 3,555E-04 0,01562234 ! negative regulation of peptidase activity GO:0010466 25 17 1,000 4,025E-04 0,0173642 ! membrane budding GO:0006900 30 17 1,000 4,025E-04 0,01705412 ! cellular response to unfolded protein GO:0034620 24 18 1,000 4,523E-04 0,01882847 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 28 18 1,000 4,523E-04 0,01850384 ! alcohol catabolic process GO:0046164 119 86 2,000 4,623E-04 0,01859455 ! carbohydrate biosynthetic process GO:0016051 111 86 2,000 4,623E-04 0,01828465 ! positive regulation of cell size GO:0045793 26 19 1,000 5,049E-04 0,01964196 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 19 1,000 5,049E-04 0,01932515 ! positive regulation of fibroblast proliferation GO:0048146 30 21 1,000 6,187E-04 0,02330438 ! apoptotic mitochondrial changes GO:0008637 42 21 1,000 6,187E-04 0,02294025 ! negative regulation of Wnt receptor signaling pathway GO:0030178 32 21 1,000 6,187E-04 0,02258732 ! carbohydrate catabolic process GO:0016052 137 100 2,000 7,183E-04 0,02582517 ! cellular response to extracellular stimulus GO:0031668 37 23 1,000 7,437E-04 0,02634177 ! positive regulation of B cell activation GO:0050871 36 23 1,000 7,437E-04 0,02595439 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 46 24 1,000 8,105E-04 0,02787273 ! osteoblast differentiation GO:0001649 43 24 1,000 8,105E-04 0,02747455 ! response to endoplasmic reticulum stress GO:0034976 32 24 1,000 8,105E-04 0,02708758 ! regulation of fibroblast proliferation GO:0048145 39 25 1,000 8,8E-04 0,02900204 ! negative regulation of phosphorylation GO:0042326 46 25 1,000 8,8E-04 0,02860476 ! ER-nuclear signaling pathway GO:0006984 33 26 1,000 9,522E-04 0,03053598 ! fat cell differentiation GO:0045444 41 27 1,000 1,027E-03 0,03250323 ! negative regulation of phosphorus metabolic process GO:0010563 51 27 1,000 1,027E-03 0,03207556 GO:0045936|negative regulation of phosphate metabolic process, ! protein targeting to membrane GO:0006612 63 33 1,000 1,535E-03 0,04730941 ! regulation of B cell activation GO:0050864 55 33 1,000 1,535E-03 0,04670288 ! negative regulation of adenylate cyclase activity GO:0007194 56 34 1,000 1,629E-03 0,04893966 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of Wnt receptor signaling pathway GO:0030111 57 34 1,000 1,629E-03 0,04832791 ! cell junction organization GO:0034330 72 35 1,000 1,726E-03 0,05056825 ! negative regulation of hydrolase activity GO:0051346 56 35 1,000 1,726E-03 0,04995157 ! glycogen metabolic process GO:0005977 53 36 1,000 1,826E-03 0,05219505 ! eye morphogenesis GO:0048592 64 36 1,000 1,826E-03 0,05157368 ! keratinocyte differentiation GO:0030216 55 37 1,000 1,928E-03 0,05381993 ! glucan metabolic process GO:0044042 54 37 1,000 1,928E-03 0,05319412 GO:0006073|cellular glucan metabolic process, ! establishment or maintenance of cell polarity GO:0007163 74 39 1,000 2,14E-03 0,05837525 ! positive regulation of leukocyte proliferation GO:0070665 64 39 1,000 2,14E-03 0,0577119 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! epidermal cell differentiation GO:0009913 61 42 1,000 2,479E-03 0,06608553 ! energy reserve metabolic process GO:0006112 67 43 1,000 2,597E-03 0,06846359 ! response to calcium ion GO:0051592 65 43 1,000 2,597E-03 0,06771125 ! positive regulation of cell cycle GO:0045787 83 45 1,000 2,84E-03 0,07326633 ! vesicle organization GO:0016050 87 48 1,000 3,226E-03 0,08230903 ! cellular polysaccharide metabolic process GO:0044264 70 50 1,000 3,495E-03 0,08824146 ! regulation of mast cell proliferation GO:0070666 80 50 1,000 3,495E-03 0,0873126 ! regulation of leukocyte proliferation GO:0070663 88 53 1,000 3,919E-03 0,09687405 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 78 58 1,000 4,675E-03 0,11437733 ! DNA damage response, signal transduction GO:0042770 105 58 1,000 4,675E-03 0,11321022 ! actin filament organization GO:0007015 107 64 1,000 5,665E-03 0,13577727 ! negative regulation of cell growth GO:0030308 123 65 1,000 5,838E-03 0,13853433 ! negative regulation of cell size GO:0045792 125 67 1,000 6,192E-03 0,14548098 ! regulation of caspase activity GO:0043281 104 68 1,000 6,373E-03 0,14825689 ! positive regulation of protein amino acid phosphorylation GO:0001934 103 68 1,000 6,373E-03 0,1468175 ! regulation of endopeptidase activity GO:0052548 106 70 1,000 6,741E-03 0,153812 ! regulation of peptidase activity GO:0052547 113 75 1,000 7,703E-03 0,17409798 ! positive regulation of phosphorylation GO:0042327 119 75 1,000 7,703E-03 0,17245555 ! response to metal ion GO:0010038 114 76 1,000 7,903E-03 0,17526856 ! positive regulation of phosphorus metabolic process GO:0010562 125 77 1,000 8,105E-03 0,17808052 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 127 78 1,000 8,309E-03 0,18089129 ! negative regulation of growth GO:0045926 140 78 1,000 8,309E-03 0,17924683 ! steroid biosynthetic process GO:0006694 111 79 1,000 8,515E-03 0,18204576 ! regulation of adenylate cyclase activity GO:0045761 143 80 1,000 8,724E-03 0,18484342 ! response to unfolded protein GO:0006986 113 80 1,000 8,724E-03 0,18320764 ! eye development GO:0001654 130 80 1,000 8,724E-03 0,18160055 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,769E-03 0,18095133 ! positive regulation of protein ubiquitination GO:0031398 8 5 0,000 8,769E-03 0,1793914 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,769E-03 0,17785814 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 5 0,000 8,769E-03 0,17635087 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,769E-03 0,17486893 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of tyrosine phosphorylation of Stat3 protein GO:0042518 13 5 0,000 8,769E-03 0,17341169 GO:0042532|negative regulation of tyrosine phosphorylation of STAT protein, ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,769E-03 0,17197853 ! regulation of cGMP biosynthetic process GO:0030826 7 5 0,000 8,769E-03 0,17056887 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,769E-03 0,16918213 ! positive regulation of actin filament polymerization GO:0030838 8 5 0,000 8,769E-03 0,16781776 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 7 5 0,000 8,769E-03 0,16647522 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,769E-03 0,16515399 ! response to oxygen radical GO:0000305 11 5 0,000 8,769E-03 0,16385356 ! negative regulation of bone resorption GO:0045779 11 5 0,000 8,769E-03 0,16257346 ! myoblast cell fate commitment GO:0048625 8 5 0,000 8,769E-03 0,1613132 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,769E-03 0,16007233 ! positive regulation of lipid biosynthetic process GO:0046889 7 5 0,000 8,769E-03 0,1588504 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,769E-03 0,15764699 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 6 5 0,000 8,769E-03 0,15646167 GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 8,769E-03 0,15529405 ! female meiosis GO:0007143 8 5 0,000 8,769E-03 0,15414372 ! nose development GO:0043584 10 5 0,000 8,769E-03 0,15301031 ! DNA catabolic process, exonucleolytic GO:0000738 7 5 0,000 8,769E-03 0,15189345 ! regulation of cell adhesion mediated by integrin GO:0033628 15 5 0,000 8,769E-03 0,15079277 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 8,769E-03 0,14970793 ! short-chain fatty acid metabolic process GO:0046459 8 5 0,000 8,769E-03 0,14863859 ! tryptophanyl-tRNA aminoacylation GO:0006436 6 5 0,000 8,769E-03 0,14758441 ! cobalt ion transport GO:0006824 9 5 0,000 8,769E-03 0,14654509 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,769E-03 0,1455203 ! SMAD protein complex assembly GO:0007183 10 5 0,000 8,769E-03 0,14450974 ! phospholipid dephosphorylation GO:0046839 7 5 0,000 8,769E-03 0,14351312 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,769E-03 0,14253015 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,769E-03 0,14156056 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,769E-03 0,14060407 ! adaptation of signaling pathway GO:0022401 9 5 0,000 8,769E-03 0,13966042 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! cardiac muscle cell proliferation GO:0060038 7 5 0,000 8,769E-03 0,13872935 GO:0014855|striated muscle cell proliferation, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,769E-03 0,13781061 ! negative regulation of gene-specific transcription GO:0032582 10 5 0,000 8,769E-03 0,13690396 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,769E-03 0,13600917 ! negative regulation of histone modification GO:0031057 7 5 0,000 8,769E-03 0,13512599 ! malate metabolic process GO:0006108 8 5 0,000 8,769E-03 0,13425421 ! positive regulation of histone modification GO:0031058 6 5 0,000 8,769E-03 0,13339361 ! transcription from mitochondrial promoter GO:0006390 8 5 0,000 8,769E-03 0,13254396 ! clathrin coat assembly GO:0048268 11 5 0,000 8,769E-03 0,13170508 ! Notch receptor processing GO:0007220 8 5 0,000 8,769E-03 0,13087675 ! phototransduction, visible light GO:0007603 7 5 0,000 8,769E-03 0,13005877 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,769E-03 0,12925095 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,769E-03 0,1284531 ! mating behavior GO:0007617 6 5 0,000 8,769E-03 0,12766505 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,769E-03 0,1268866 ! copulation GO:0007620 8 5 0,000 8,769E-03 0,12611759 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,769E-03 0,12535785 ! embryonic hemopoiesis GO:0035162 13 5 0,000 8,769E-03 0,1246072 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,769E-03 0,12386549 ! apoptotic cell clearance GO:0043277 14 5 0,000 8,769E-03 0,12313256 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 9 5 0,000 8,769E-03 0,12240825 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,769E-03 0,12169241 ! fructose 1,6-bisphosphate metabolic process GO:0030388 8 5 0,000 8,769E-03 0,1209849 ! regulation of smooth muscle cell apoptosis GO:0034391 8 5 0,000 8,769E-03 0,12028556 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 8,769E-03 0,11959427 GO:0046329|negative regulation of JNK cascade, ! oocyte maturation GO:0001556 6 5 0,000 8,769E-03 0,11891087 ! response to axon injury GO:0048678 8 5 0,000 8,769E-03 0,11823524 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,769E-03 0,11756725 ! response to protozoan GO:0001562 10 5 0,000 8,769E-03 0,11690676 ! negative regulation of heart contraction GO:0045822 12 5 0,000 8,769E-03 0,11625365 ! lymph vessel development GO:0001945 8 5 0,000 8,769E-03 0,11560779 ! regulation of activin receptor signaling pathway GO:0032925 11 5 0,000 8,769E-03 0,11496907 ! endochondral ossification GO:0001958 13 5 0,000 8,769E-03 0,11433738 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,769E-03 0,11371258 ! single strand break repair GO:0000012 5 5 0,000 8,769E-03 0,11309458 ! parathyroid gland development GO:0060017 8 5 0,000 8,769E-03 0,11248326 ! anagen GO:0042640 7 5 0,000 8,769E-03 0,11187851 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,769E-03 0,11128023 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,769E-03 0,11068831 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,769E-03 0,11010266 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 8 5 0,000 8,769E-03 0,10952317 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 8 5 0,000 8,769E-03 0,10894975 ! smooth muscle tissue development GO:0048745 14 5 0,000 8,769E-03 0,1083823 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,769E-03 0,10782074 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,769E-03 0,10726496 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,769E-03 0,10671488 ! cardiac muscle fiber development GO:0048739 8 5 0,000 8,769E-03 0,10617042 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,769E-03 0,10563148 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 8 5 0,000 8,769E-03 0,10509799 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,769E-03 0,10456986 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,769E-03 0,10404701 ! regulation of oligodendrocyte differentiation GO:0048713 15 5 0,000 8,769E-03 0,10352937 GO:0048715|negative regulation of oligodendrocyte differentiation, ! mitochondrion localization, microtubule-mediated GO:0034643 9 5 0,000 8,769E-03 0,10301684 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 8,769E-03 0,10250937 ! ionotropic glutamate receptor signaling pathway GO:0035235 10 5 0,000 8,769E-03 0,10200687 ! positive regulation of isotype switching to IgG isotypes GO:0048304 8 5 0,000 8,769E-03 0,10150928 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,769E-03 0,10101652 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 9 5 0,000 8,769E-03 0,10052851 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,769E-03 0,1000452 ! tyrosine catabolic process GO:0006572 7 5 0,000 8,769E-03 0,09956652 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,769E-03 0,09909239 ! proline biosynthetic process GO:0006561 6 5 0,000 8,769E-03 0,09862276 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,769E-03 0,09815756 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,769E-03 0,09769673 ! polyol biosynthetic process GO:0046173 6 5 0,000 8,769E-03 0,0972402 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,769E-03 0,09678792 ! sister chromatid cohesion GO:0007062 10 5 0,000 8,769E-03 0,09633983 ! response to ATP GO:0033198 6 5 0,000 8,769E-03 0,09589586 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 9 5 0,000 8,769E-03 0,09545597 ! positive regulation of stress fiber formation GO:0051496 15 5 0,000 8,769E-03 0,0950201 ! neutrophil activation GO:0042119 6 5 0,000 8,769E-03 0,09458819 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,769E-03 0,09416019 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,769E-03 0,09373605 ! response to food GO:0032094 5 5 0,000 8,769E-03 0,09331571 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,769E-03 0,09289912 GO:0043088|regulation of Cdc42 GTPase activity, ! positive regulation of transporter activity GO:0032411 5 5 0,000 8,769E-03 0,09248623 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 8 5 0,000 8,769E-03 0,092077 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,769E-03 0,09167138 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,769E-03 0,09126931 ! forebrain neuron development GO:0021884 7 5 0,000 8,769E-03 0,09087075 ! melanosome organization GO:0032438 7 5 0,000 8,769E-03 0,09047566 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,769E-03 0,09008399 ! virus-infected cell apoptosis GO:0006926 8 5 0,000 8,769E-03 0,0896957 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,769E-03 0,08931074 ! positive regulation of neuroblast proliferation GO:0002052 9 5 0,000 8,769E-03 0,08892907 ! mesodermal cell fate determination GO:0007500 7 5 0,000 8,769E-03 0,08855065 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,769E-03 0,08817543 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 8 5 0,000 8,769E-03 0,08780339 ! nucleoside salvage GO:0043174 7 5 0,000 8,769E-03 0,08743446 GO:0006166|purine ribonucleoside salvage, ! lipid glycosylation GO:0030259 6 5 0,000 8,769E-03 0,08706863 ! attachment of GPI anchor to protein GO:0016255 10 5 0,000 8,769E-03 0,08670584 ! negative regulation of platelet activation GO:0010544 8 5 0,000 8,769E-03 0,08634607 GO:0010543|regulation of platelet activation, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,769E-03 0,08598927 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,769E-03 0,0856354 ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 8,769E-03 0,08528444 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of fatty acid metabolic process GO:0045923 6 5 0,000 8,769E-03 0,08493634 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,769E-03 0,08459107 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 6 5 0,000 8,769E-03 0,08424859 ! depyrimidination GO:0045008 8 5 0,000 8,769E-03 0,08390888 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,769E-03 0,0835719 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,769E-03 0,08323761 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 5 0,000 8,769E-03 0,08290599 ! neuronal ion channel clustering GO:0045161 8 5 0,000 8,769E-03 0,08257699 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,769E-03 0,0822506 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,769E-03 0,08192678 ! monocyte differentiation GO:0030224 7 5 0,000 8,769E-03 0,0816055 ! negative regulation of peptide secretion GO:0002792 8 5 0,000 8,769E-03 0,08128673 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 6 5 0,000 8,769E-03 0,08097044 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,769E-03 0,0806566 ! response to UV-C GO:0010225 7 5 0,000 8,769E-03 0,08034518 ! protein targeting to vacuole GO:0006623 6 5 0,000 8,769E-03 0,08003616 ! activated T cell proliferation GO:0050798 7 5 0,000 8,769E-03 0,07972951 ! negative regulation of alpha-beta T cell activation GO:0046636 7 5 0,000 8,769E-03 0,0794252 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of alpha-beta T cell proliferation GO:0046640 13 5 0,000 8,769E-03 0,0791232 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,769E-03 0,07882349 ! regulation of integrin biosynthetic process GO:0045113 9 5 0,000 8,769E-03 0,07852605 ! regulation of killing of cells of another organism GO:0051709 6 5 0,000 8,769E-03 0,07823084 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,769E-03 0,07793784 ! lymphoid progenitor cell differentiation GO:0002320 12 5 0,000 8,769E-03 0,07764702 ! positive regulation of T cell cytokine production GO:0002726 9 5 0,000 8,769E-03 0,07735837 GO:0032743|positive regulation of interleukin-2 production, ! L-ascorbic acid metabolic process GO:0019852 7 5 0,000 8,769E-03 0,07707186 ! base-excision repair, DNA ligation GO:0006288 5 5 0,000 8,769E-03 0,07678746 ! response to cadmium ion GO:0046686 8 5 0,000 8,769E-03 0,07650516 ! melanosome transport GO:0032402 8 5 0,000 8,769E-03 0,07622492 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 8,769E-03 0,07594672 ! regulation of acetylcholine secretion GO:0014056 10 5 0,000 8,769E-03 0,07567055 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,769E-03 0,07539639 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,769E-03 0,0751242 ! positive T cell selection GO:0043368 10 5 0,000 8,769E-03 0,07485397 ! purine deoxyribonucleotide catabolic process GO:0009155 6 5 0,000 8,769E-03 0,07458567 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 8,769E-03 0,07431929 ! regulation of interleukin-1 production GO:0032652 8 5 0,000 8,769E-03 0,07405481 ! ribosomal subunit assembly GO:0042257 5 5 0,000 8,769E-03 0,07379221 ! base conversion or substitution editing GO:0016553 6 5 0,000 8,769E-03 0,07353146 ! regulation of chondrocyte differentiation GO:0032330 9 5 0,000 8,769E-03 0,07327254 ! negative regulation of monooxygenase activity GO:0032769 10 5 0,000 8,769E-03 0,07301545 ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 8,769E-03 0,07276015 ! positive regulation of interleukin-12 production GO:0032735 5 5 0,000 8,769E-03 0,07250663 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,769E-03 0,07225487 ! histone demethylation GO:0016577 10 5 0,000 8,769E-03 0,07200485 ! mitotic recombination GO:0006312 10 5 0,000 8,769E-03 0,07175656 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 5 0,000 8,769E-03 0,07150997 ! regulation of sterol transport GO:0032371 7 5 0,000 8,769E-03 0,07126508 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,769E-03 0,07102185 ! sympathetic nervous system development GO:0048485 13 5 0,000 8,769E-03 0,07078028 ! enteric nervous system development GO:0048484 9 5 0,000 8,769E-03 0,07054035 ! oxygen homeostasis GO:0032364 8 5 0,000 8,769E-03 0,07030204 ! establishment of planar polarity GO:0001736 7 5 0,000 8,769E-03 0,07006533 ! lymphocyte costimulation GO:0031294 12 5 0,000 8,769E-03 0,06983021 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 6 5 0,000 8,769E-03 0,06959666 ! transcription termination GO:0006353 8 5 0,000 8,769E-03 0,06936467 ! plasminogen activation GO:0031639 5 5 0,000 8,769E-03 0,06913423 ! B cell homeostasis GO:0001782 12 5 0,000 8,769E-03 0,06890531 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,769E-03 0,0686779 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,769E-03 0,06845198 ! regulation of hair follicle development GO:0051797 9 5 0,000 8,769E-03 0,06822755 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,769E-03 0,06800458 ! apical protein localization GO:0045176 8 5 0,000 8,769E-03 0,06778307 ! definitive hemopoiesis GO:0060216 5 5 0,000 8,769E-03 0,067563 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 8,769E-03 0,06734434 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,769E-03 0,0671271 ! glucocorticoid biosynthetic process GO:0006704 6 5 0,000 8,769E-03 0,06691126 ! regulation of keratinocyte differentiation GO:0045616 7 5 0,000 8,769E-03 0,0666968 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,769E-03 0,06648371 ! regulation of centrosome duplication GO:0010824 6 5 0,000 8,769E-03 0,06627198 ! disaccharide metabolic process GO:0005984 9 5 0,000 8,769E-03 0,0660616 ! galactolipid metabolic process GO:0019374 8 5 0,000 8,769E-03 0,06585254 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,769E-03 0,0656448 GO:0033015|tetrapyrrole catabolic process, ! positive regulation of T cell mediated cytotoxicity GO:0001916 11 5 0,000 8,769E-03 0,06543837 ! determination of adult lifespan GO:0008340 8 5 0,000 8,769E-03 0,06523324 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,769E-03 0,06502938 ! ectodermal gut morphogenesis GO:0048567 6 5 0,000 8,769E-03 0,0648268 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 14 5 0,000 8,769E-03 0,06462547 ! T cell activation during immune response GO:0002286 9 5 0,000 8,769E-03 0,06442539 ! negative regulation of fibrinolysis GO:0051918 9 5 0,000 8,769E-03 0,06422655 ! negative regulation of lipase activity GO:0060192 7 5 0,000 8,769E-03 0,06402893 ! neural plate development GO:0001840 7 5 0,000 8,769E-03 0,06383252 ! regulation of sensory perception GO:0051931 6 5 0,000 8,769E-03 0,06363732 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 10 5 0,000 8,769E-03 0,0634433 ! regulation of histone acetylation GO:0035065 7 5 0,000 8,769E-03 0,06325046 ! sensory cilium assembly GO:0035058 6 5 0,000 8,769E-03 0,0630588 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 14 5 0,000 8,769E-03 0,06286829 ! diacylglycerol metabolic process GO:0046339 8 5 0,000 8,769E-03 0,06267892 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,769E-03 0,0624907 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 11 5 0,000 8,769E-03 0,0623036 ! negative regulation of smooth muscle contraction GO:0045986 10 5 0,000 8,769E-03 0,06211762 ! receptor biosynthetic process GO:0032800 6 5 0,000 8,769E-03 0,06193275 ! penetration of zona pellucida GO:0007341 9 5 0,000 8,769E-03 0,06174897 ! drug metabolic process GO:0017144 5 5 0,000 8,769E-03 0,06156628 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,769E-03 0,06138467 ! organ regeneration GO:0031100 7 5 0,000 8,769E-03 0,06120412 ! carnitine metabolic process GO:0009437 5 5 0,000 8,769E-03 0,06102464 GO:0006577|betaine metabolic process, ! response to inorganic substance GO:0010035 127 81 1,000 8,935E-03 0,0619979 ! regulation of cAMP biosynthetic process GO:0030817 148 82 1,000 9,149E-03 0,06329305 ! regulation of cyclase activity GO:0031279 146 82 1,000 9,149E-03 0,06310905 ! positive regulation of protein modification process GO:0031401 126 83 1,000 9,364E-03 0,06440911 ! regulation of lyase activity GO:0051339 147 83 1,000 9,364E-03 0,06422296 ! positive regulation of lymphocyte activation GO:0051251 134 83 1,000 9,364E-03 0,06403788 ! regulation of cAMP metabolic process GO:0030814 153 84 1,000 9,582E-03 0,06533951 ! cellular respiration GO:0045333 119 85 1,000 9,802E-03 0,06664903 ! response to protein stimulus GO:0051789 127 85 1,000 9,802E-03 0,06645861 ! regulation of nucleotide biosynthetic process GO:0030808 155 87 1,000 0,01024915 0,06929126 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! Golgi vesicle transport GO:0048193 145 87 1,000 0,01024915 0,06909441 ! tRNA transcription GO:0009304 11 6 0,000 0,0105141 0,07067977 ! negative regulation of S phase of mitotic cell cycle GO:0045749 13 6 0,000 0,0105141 0,07048011 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0105141 0,07028157 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 8 6 0,000 0,0105141 0,07008415 ! regulation of helicase activity GO:0051095 11 6 0,000 0,0105141 0,06988784 ! regulation of cGMP metabolic process GO:0030823 8 6 0,000 0,0105141 0,06969262 ! sleep GO:0030431 13 6 0,000 0,0105141 0,06949849 ! positive regulation of axon extension GO:0045773 10 6 0,000 0,0105141 0,06930544 ! negative regulation of small GTPase mediated signal transduction GO:0051058 11 6 0,000 0,0105141 0,06911346 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,0105141 0,06892254 ! forebrain regionalization GO:0021871 7 6 0,000 0,0105141 0,06873267 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,0105141 0,06854384 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,0105141 0,06835605 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,0105141 0,06816928 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,0105141 0,06798354 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 18 6 0,000 0,0105141 0,0677988 ! regulation of protein export from nucleus GO:0046825 8 6 0,000 0,0105141 0,06761506 ! neuron adhesion GO:0007158 9 6 0,000 0,0105141 0,06743232 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,0105141 0,06725056 ! signal peptide processing GO:0006465 8 6 0,000 0,0105141 0,06706978 ! embryonic camera-type eye development GO:0031076 11 6 0,000 0,0105141 0,06688997 GO:0048596|embryonic camera-type eye morphogenesis, ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,0105141 0,06671112 ! glucocorticoid receptor signaling pathway GO:0042921 11 6 0,000 0,0105141 0,06653322 GO:0031958|corticosteroid receptor signaling pathway, ! citrate metabolic process GO:0006101 10 6 0,000 0,0105141 0,06635627 ! fibril organization GO:0043206 13 6 0,000 0,0105141 0,06618026 ! regulation of mitochondrial membrane permeability GO:0046902 12 6 0,000 0,0105141 0,06600518 ! neurofilament cytoskeleton organization GO:0060052 10 6 0,000 0,0105141 0,06583102 ! posttranscriptional gene silencing by RNA GO:0035194 14 6 0,000 0,0105141 0,06565778 GO:0016441|posttranscriptional gene silencing, ! behavioral response to pain GO:0048266 10 6 0,000 0,0105141 0,06548545 ! protein refolding GO:0042026 13 6 0,000 0,0105141 0,06531403 ! metabotropic glutamate receptor signaling pathway GO:0007216 8 6 0,000 0,0105141 0,06514349 ! rhythmic behavior GO:0007622 14 6 0,000 0,0105141 0,06497385 ! glial cell fate commitment GO:0021781 17 6 0,000 0,0105141 0,06480509 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0105141 0,0646372 ! sensory perception of temperature stimulus GO:0050951 12 6 0,000 0,0105141 0,06447018 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0105141 0,06430402 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0105141 0,06413871 ! regulation of odontogenesis GO:0042481 8 6 0,000 0,0105141 0,06397425 ! mechanosensory behavior GO:0007638 8 6 0,000 0,0105141 0,06381064 ! ovulation from ovarian follicle GO:0001542 7 6 0,000 0,0105141 0,06364785 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,0105141 0,0634859 ! response to interferon-gamma GO:0034341 12 6 0,000 0,0105141 0,06332477 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,0105141 0,06316445 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 9 6 0,000 0,0105141 0,06300495 ! negative regulation of viral genome replication GO:0045071 8 6 0,000 0,0105141 0,06284624 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 6 6 0,000 0,0105141 0,06268834 ! spinal cord dorsal/ventral patterning GO:0021513 8 6 0,000 0,0105141 0,06253122 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 17 6 0,000 0,0105141 0,0623749 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 11 6 0,000 0,0105141 0,06221935 ! cGMP-mediated signaling GO:0019934 11 6 0,000 0,0105141 0,06206457 ! activation of MAPKKK activity GO:0000185 11 6 0,000 0,0105141 0,06191057 ! inositol phosphate-mediated signaling GO:0048016 10 6 0,000 0,0105141 0,06175732 ! protein lipoylation GO:0009249 10 6 0,000 0,0105141 0,06160484 ! pigment granule organization GO:0048753 11 6 0,000 0,0105141 0,0614531 ! drug transport GO:0015893 6 6 0,000 0,0105141 0,06130211 ! transepithelial chloride transport GO:0030321 10 6 0,000 0,0105141 0,06115186 GO:0070633|transepithelial transport, ! cysteine metabolic process GO:0006534 8 6 0,000 0,0105141 0,06100234 ! negative regulation of survival gene product expression GO:0008634 9 6 0,000 0,0105141 0,06085356 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,0105141 0,06070549 ! regulation of defense response to virus by host GO:0050691 7 6 0,000 0,0105141 0,06055815 ! glutamate catabolic process GO:0006538 11 6 0,000 0,0105141 0,06041152 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,0105141 0,0602656 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,0105141 0,06012038 ! adenohypophysis development GO:0021984 10 6 0,000 0,0105141 0,05997586 ! response to pH GO:0009268 10 6 0,000 0,0105141 0,05983203 ! hyperosmotic response GO:0006972 9 6 0,000 0,0105141 0,0596889 ! microtubule nucleation GO:0007020 10 6 0,000 0,0105141 0,05954644 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 6 0,000 0,0105141 0,05940466 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 6 0,000 0,0105141 0,05926356 ! melanin biosynthetic process from tyrosine GO:0006583 9 6 0,000 0,0105141 0,05912312 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,0105141 0,05898335 ! vascular smooth muscle contraction GO:0014829 11 6 0,000 0,0105141 0,05884424 ! regulation of retinoic acid receptor signaling pathway GO:0048385 13 6 0,000 0,0105141 0,05870578 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,0105141 0,05856798 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,0105141 0,05843082 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,0105141 0,0582943 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,0105141 0,05815841 ! purine salvage GO:0043101 9 6 0,000 0,0105141 0,05802316 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0105141 0,05788853 ! peptidyl-threonine phosphorylation GO:0018107 16 6 0,000 0,0105141 0,05775453 ! nucleoside transport GO:0015858 7 6 0,000 0,0105141 0,05762115 ! organic alcohol transport GO:0015850 9 6 0,000 0,0105141 0,05748838 ! T cell mediated immunity GO:0002456 12 6 0,000 0,0105141 0,05735623 ! folic acid transport GO:0015884 11 6 0,000 0,0105141 0,05722467 ! male sex determination GO:0030238 11 6 0,000 0,0105141 0,05709373 ! carnitine transport GO:0015879 8 6 0,000 0,0105141 0,05696338 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,0105141 0,05683362 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0105141 0,05670445 ! negative regulation of DNA recombination GO:0045910 10 6 0,000 0,0105141 0,05657587 ! positive regulation of exocytosis GO:0045921 9 6 0,000 0,0105141 0,05644787 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,0105141 0,05632045 ! parturition GO:0007567 13 6 0,000 0,0105141 0,0561936 ! determination of anterior/posterior axis, embryo GO:0008595 10 6 0,000 0,0105141 0,05606732 GO:0007351|tripartite regional subdivision, ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,0105141 0,05594161 ! lipopolysaccharide biosynthetic process GO:0009103 6 6 0,000 0,0105141 0,05581646 ! regulation of centrosome cycle GO:0046605 8 6 0,000 0,0105141 0,05569187 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,0105141 0,05556784 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,0105141 0,05544435 ! regulation of cholesterol biosynthetic process GO:0045540 8 6 0,000 0,0105141 0,05532142 ! homeostasis of number of cells within a tissue GO:0048873 10 6 0,000 0,0105141 0,05519902 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0105141 0,05507717 ! negative regulation of gliogenesis GO:0014014 17 6 0,000 0,0105141 0,05495586 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 10 6 0,000 0,0105141 0,05483507 ! neural nucleus development GO:0048857 12 6 0,000 0,0105141 0,05471482 ! forebrain morphogenesis GO:0048853 14 6 0,000 0,0105141 0,05459509 ! hyaluronan metabolic process GO:0030212 7 6 0,000 0,0105141 0,05447589 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,0105141 0,05435721 ! interaction with symbiont GO:0051702 9 6 0,000 0,0105141 0,05423904 ! regulation of dendrite development GO:0050773 13 6 0,000 0,0105141 0,05412138 ! anterograde axon cargo transport GO:0008089 9 6 0,000 0,0105141 0,05400424 ! positive regulation of organ growth GO:0046622 7 6 0,000 0,0105141 0,0538876 ! eating behavior GO:0042755 6 6 0,000 0,0105141 0,05377146 ! regulation of T cell cytokine production GO:0002724 11 6 0,000 0,0105141 0,05365582 ! transcription-coupled nucleotide-excision repair GO:0006283 7 6 0,000 0,0105141 0,05354068 ! response to copper ion GO:0046688 9 6 0,000 0,0105141 0,05342603 ! negative regulation of lymphocyte mediated immunity GO:0002707 13 6 0,000 0,0105141 0,05331188 GO:0002704|negative regulation of leukocyte mediated immunity, ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,0105141 0,05319821 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,0105141 0,05308502 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0105141 0,05297231 ! negative regulation of protein kinase B signaling cascade GO:0051898 12 6 0,000 0,0105141 0,05286008 ! positive regulation of B cell differentiation GO:0045579 10 6 0,000 0,0105141 0,05274833 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0105141 0,05263704 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0105141 0,05252623 ! hair follicle maturation GO:0048820 8 6 0,000 0,0105141 0,05241588 ! cranial nerve morphogenesis GO:0021602 7 6 0,000 0,0105141 0,05230599 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0105141 0,05219657 ! positive regulation of interleukin-5 production GO:0032754 9 6 0,000 0,0105141 0,0520876 GO:0032736|positive regulation of interleukin-13 production, ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,0105141 0,05197908 ! rhombomere development GO:0021546 6 6 0,000 0,0105141 0,05187102 ! positive regulation of Rho GTPase activity GO:0032321 12 6 0,000 0,0105141 0,0517634 ! G2 phase GO:0051319 15 6 0,000 0,0105141 0,05165623 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 10 6 0,000 0,0105141 0,0515495 GO:0050000|chromosome localization, ! regulation of mast cell activation GO:0033003 7 6 0,000 0,0105141 0,05144321 ! muscle cell proliferation GO:0033002 9 6 0,000 0,0105141 0,05133736 ! membrane to membrane docking GO:0022614 12 6 0,000 0,0105141 0,05123195 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 10 6 0,000 0,0105141 0,05112696 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 12 6 0,000 0,0105141 0,05102241 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 6 0,000 0,0105141 0,05091828 ! receptor internalization GO:0031623 9 6 0,000 0,0105141 0,05081458 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0105141 0,0507113 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 9 6 0,000 0,0105141 0,05060843 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,0105141 0,05050599 ! myeloid dendritic cell activation GO:0001773 11 6 0,000 0,0105141 0,05040396 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 12 6 0,000 0,0105141 0,05030234 ! peptidyl-histidine modification GO:0018202 10 6 0,000 0,0105141 0,05020112 ! axonal fasciculation GO:0007413 10 6 0,000 0,0105141 0,05010032 ! regulation of muscle cell apoptosis GO:0010660 9 6 0,000 0,0105141 0,04999992 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 0,0105141 0,04989992 GO:0015991|ATP hydrolysis coupled proton transport, ! midbrain development GO:0030901 7 6 0,000 0,0105141 0,04980032 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 0,0105141 0,04970111 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0105141 0,0496023 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 7 6 0,000 0,0105141 0,04950389 ! progesterone metabolic process GO:0042448 8 6 0,000 0,0105141 0,04940586 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,0105141 0,04930822 ! glycolipid catabolic process GO:0019377 14 6 0,000 0,0105141 0,04921096 GO:0046479|glycosphingolipid catabolic process, ! nonprotein amino acid metabolic process GO:0019794 10 6 0,000 0,0105141 0,04911409 ! negative regulation of axon extension GO:0030517 13 6 0,000 0,0105141 0,0490176 ! removal of superoxide radicals GO:0019430 10 6 0,000 0,0105141 0,04892149 ! triglyceride catabolic process GO:0019433 8 6 0,000 0,0105141 0,04882575 ! protein modification by small protein removal GO:0070646 10 6 0,000 0,0105141 0,04873039 GO:0016579|protein deubiquitination, ! adult feeding behavior GO:0008343 6 6 0,000 0,0105141 0,0486354 ! regulation of Rac protein signal transduction GO:0035020 9 6 0,000 0,0105141 0,04854077 ! glial cell migration GO:0008347 11 6 0,000 0,0105141 0,04844652 ! blastocyst growth GO:0001832 17 6 0,000 0,0105141 0,04835263 ! pigment granule transport GO:0051904 12 6 0,000 0,0105141 0,04825911 ! lymphocyte activation during immune response GO:0002285 10 6 0,000 0,0105141 0,04816594 ! cerebellar cortex formation GO:0021697 9 6 0,000 0,0105141 0,04807314 ! catecholamine transport GO:0051937 7 6 0,000 0,0105141 0,04798069 ! hemopoietic progenitor cell differentiation GO:0002244 14 6 0,000 0,0105141 0,0478886 ! positive regulation of actin filament bundle formation GO:0032233 16 6 0,000 0,0105141 0,04779685 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0105141 0,04770547 ! positive regulation of smooth muscle contraction GO:0045987 10 6 0,000 0,0105141 0,04761442 ! ensheathment of axons in the peripheral nervous system GO:0032292 15 6 0,000 0,0105141 0,04752373 GO:0022011|myelination in the peripheral nervous system, ! protein prenylation GO:0018342 10 6 0,000 0,0105141 0,04743338 ! negative regulation of synaptic transmission GO:0050805 12 6 0,000 0,0105141 0,04734337 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,0105141 0,04725371 ! NAD biosynthetic process GO:0009435 9 6 0,000 0,0105141 0,04716438 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,0105141 0,04707539 ! cellular anion homeostasis GO:0030002 9 6 0,000 0,0105141 0,04698674 GO:0055081|anion homeostasis, ! ossification GO:0001503 150 89 1,000 0,01070508 0,04775028 GO:0060348|bone development, ! regulation of cyclic nucleotide metabolic process GO:0030799 161 90 1,000 0,01093637 0,04869045 ! positive regulation of cell activation GO:0050867 146 90 1,000 0,01093637 0,04859927 GO:0002696|positive regulation of leukocyte activation, ! cell cycle arrest GO:0007050 171 93 1,000 0,01164347 0,05164479 ! regulation of nucleotide metabolic process GO:0006140 164 93 1,000 0,01164347 0,05154844 ! behavioral response to cocaine GO:0048148 13 7 0,000 0,01225598 0,05415909 ! autophagic vacuole formation GO:0000045 12 7 0,000 0,01225598 0,05405843 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01225598 0,05395813 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 10 7 0,000 0,01225598 0,05385821 ! chaperone mediated protein folding requiring cofactor GO:0051085 9 7 0,000 0,01225598 0,05375866 ! prostate gland development GO:0030850 11 7 0,000 0,01225598 0,05365947 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01225598 0,05356065 ! regulation of hormone biosynthetic process GO:0046885 12 7 0,000 0,01225598 0,05346219 ! synaptonemal complex assembly GO:0007130 11 7 0,000 0,01225598 0,0533641 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 10 7 0,000 0,01225598 0,05326636 ! male meiosis GO:0007140 10 7 0,000 0,01225598 0,05316898 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01225598 0,05307196 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! reproductive behavior GO:0019098 12 7 0,000 0,01225598 0,05297529 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01225598 0,05287897 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01225598 0,052783 ! oligopeptide transport GO:0006857 11 7 0,000 0,01225598 0,05268738 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01225598 0,0525921 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 9 7 0,000 0,01225598 0,05249717 ! establishment of tissue polarity GO:0007164 10 7 0,000 0,01225598 0,05240258 ! receptor guanylyl cyclase signaling pathway GO:0007168 7 7 0,000 0,01225598 0,05230833 ! RNA methylation GO:0001510 11 7 0,000 0,01225598 0,05221442 ! negative regulation of cell-cell adhesion GO:0022408 20 7 0,000 0,01225598 0,05212085 ! positive regulation of cell-cell adhesion GO:0022409 17 7 0,000 0,01225598 0,05202761 ! pericardium development GO:0060039 9 7 0,000 0,01225598 0,0519347 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01225598 0,05184213 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01225598 0,05174988 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01225598 0,05165796 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01225598 0,05156637 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01225598 0,0514751 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01225598 0,05138416 ! opsonization GO:0008228 9 7 0,000 0,01225598 0,05129353 ! tachykinin receptor signaling pathway GO:0007217 12 7 0,000 0,01225598 0,05120323 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01225598 0,05111324 ! regulation of dopamine metabolic process GO:0042053 10 7 0,000 0,01225598 0,05102357 GO:0042069|regulation of catecholamine metabolic process, ! glucocorticoid metabolic process GO:0008211 8 7 0,000 0,01225598 0,05093421 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01225598 0,05084516 ! chemosensory behavior GO:0007635 9 7 0,000 0,01225598 0,05075643 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01225598 0,050668 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01225598 0,05057988 ! leukocyte degranulation GO:0043299 11 7 0,000 0,01225598 0,05049207 ! positive regulation of glycolysis GO:0045821 13 7 0,000 0,01225598 0,05040456 ! DNA ligation during DNA repair GO:0051103 10 7 0,000 0,01225598 0,05031736 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01225598 0,05023045 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01225598 0,05014385 ! lipopolysaccharide metabolic process GO:0008653 7 7 0,000 0,01225598 0,05005754 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01225598 0,04997153 ! spinal cord patterning GO:0021511 9 7 0,000 0,01225598 0,04988582 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01225598 0,0498004 ! thymic T cell selection GO:0045061 15 7 0,000 0,01225598 0,04971527 ! regulation of transcriptional preinitiation complex assembly GO:0045898 11 7 0,000 0,01225598 0,04963043 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01225598 0,04954588 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01225598 0,04946162 ! ovulation GO:0030728 8 7 0,000 0,01225598 0,04937765 ! regulation of isotype switching to IgG isotypes GO:0048302 11 7 0,000 0,01225598 0,04929395 ! histidine metabolic process GO:0006547 7 7 0,000 0,01225598 0,04921055 GO:0009075|histidine family amino acid metabolic process, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 7 0,000 0,01225598 0,04912742 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01225598 0,04904458 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! deoxyribonucleotide biosynthetic process GO:0009263 9 7 0,000 0,01225598 0,04896201 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 0,01225598 0,04887972 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! ER overload response GO:0006983 8 7 0,000 0,01225598 0,04879771 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01225598 0,04871597 ! endosome organization GO:0007032 10 7 0,000 0,01225598 0,0486345 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01225598 0,04855331 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of interleukin-8 biosynthetic process GO:0045416 8 7 0,000 0,01225598 0,04847239 ! phasic smooth muscle contraction GO:0014821 13 7 0,000 0,01225598 0,04839174 ! urea metabolic process GO:0019627 9 7 0,000 0,01225598 0,04831135 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 14 7 0,000 0,01225598 0,04823123 ! vesicle fusion GO:0006906 15 7 0,000 0,01225598 0,04815138 ! positive regulation of insulin secretion GO:0032024 9 7 0,000 0,01225598 0,04807179 ! maintenance of protein location in nucleus GO:0051457 17 7 0,000 0,01225598 0,04799246 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01225598 0,0479134 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 10 7 0,000 0,01225598 0,04783459 GO:0046464|acylglycerol catabolic process, ! asymmetric protein localization GO:0008105 10 7 0,000 0,01225598 0,04775605 ! organ growth GO:0035265 13 7 0,000 0,01225598 0,04767776 ! positive regulation of mesenchymal cell proliferation GO:0002053 10 7 0,000 0,01225598 0,04759973 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01225598 0,04752195 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 7 0,000 0,01225598 0,04744443 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 8 7 0,000 0,01225598 0,04736716 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! retinol metabolic process GO:0042572 9 7 0,000 0,01225598 0,04729014 ! positive regulation of mitotic cell cycle GO:0045931 13 7 0,000 0,01225598 0,04721337 ! rRNA modification GO:0000154 12 7 0,000 0,01225598 0,04713684 ! negative regulation of translational initiation GO:0045947 9 7 0,000 0,01225598 0,04706057 ! DNA damage response, signal transduction resulting in transcription GO:0042772 14 7 0,000 0,01225598 0,04698455 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 20 7 0,000 0,01225598 0,04690876 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01225598 0,04683323 ! response to UV-B GO:0010224 11 7 0,000 0,01225598 0,04675793 ! astrocyte development GO:0014002 15 7 0,000 0,01225598 0,04668288 ! intermediate filament organization GO:0045109 12 7 0,000 0,01225598 0,04660807 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01225598 0,04653349 ! fibrinolysis GO:0042730 9 7 0,000 0,01225598 0,04645916 ! peptidyl-arginine modification GO:0018195 9 7 0,000 0,01225598 0,04638506 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 7 0,000 0,01225598 0,0463112 ! blastoderm segmentation GO:0007350 11 7 0,000 0,01225598 0,04623757 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01225598 0,04616418 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01225598 0,04609102 ! DNA topological change GO:0006265 10 7 0,000 0,01225598 0,04601809 ! regulation of fat cell differentiation GO:0045598 10 7 0,000 0,01225598 0,04594539 ! melanosome localization GO:0032400 10 7 0,000 0,01225598 0,04587292 ! enucleate erythrocyte differentiation GO:0043353 10 7 0,000 0,01225598 0,04580068 ! regulation of interleukin-5 production GO:0032674 10 7 0,000 0,01225598 0,04572867 ! glycosylceramide metabolic process GO:0006677 10 7 0,000 0,01225598 0,04565688 ! mast cell activation GO:0045576 10 7 0,000 0,01225598 0,04558532 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01225598 0,04551398 ! negative regulation of focal adhesion formation GO:0051895 16 7 0,000 0,01225598 0,04544286 ! gas homeostasis GO:0033483 12 7 0,000 0,01225598 0,04537197 ! negative regulation of T cell differentiation GO:0045581 9 7 0,000 0,01225598 0,0453013 ! phosphatidylinositol biosynthetic process GO:0006661 11 7 0,000 0,01225598 0,04523085 ! Schwann cell development GO:0014044 16 7 0,000 0,01225598 0,04516061 ! dendrite morphogenesis GO:0048813 12 7 0,000 0,01225598 0,04509059 ! regulation of interleukin-13 production GO:0032656 12 7 0,000 0,01225598 0,04502079 ! positive regulation of interleukin-4 production GO:0032753 10 7 0,000 0,01225598 0,04495121 ! molybdopterin cofactor biosynthetic process GO:0032324 10 7 0,000 0,01225598 0,04488184 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 11 7 0,000 0,01225598 0,04481269 ! neural tube patterning GO:0021532 8 7 0,000 0,01225598 0,04474374 ! histone ubiquitination GO:0016574 10 7 0,000 0,01225598 0,04467501 ! regulation of meiosis GO:0040020 12 7 0,000 0,01225598 0,04460649 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 12 7 0,000 0,01225598 0,04453818 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01225598 0,04447008 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 12 7 0,000 0,01225598 0,04440219 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01225598 0,0443345 ! regulation of cell division GO:0051302 9 7 0,000 0,01225598 0,04426702 ! regulation of inflammatory response to antigenic stimulus GO:0002861 14 7 0,000 0,01225598 0,04419975 ! neutrophil homeostasis GO:0001780 8 7 0,000 0,01225598 0,04413268 ! regulation of macrophage activation GO:0043030 12 7 0,000 0,01225598 0,04406581 ! negative regulation of nuclear division GO:0051784 18 7 0,000 0,01225598 0,04399914 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01225598 0,04393268 ! diuresis GO:0030146 11 7 0,000 0,01225598 0,04386642 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 9 7 0,000 0,01225598 0,04380035 ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01225598 0,04373449 ! thiamin metabolic process GO:0006772 8 7 0,000 0,01225598 0,04366882 ! positive regulation of leukocyte chemotaxis GO:0002690 15 7 0,000 0,01225598 0,04360335 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 10 7 0,000 0,01225598 0,04353807 ! negative regulation of transmission of nerve impulse GO:0051970 13 7 0,000 0,01225598 0,04347299 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01225598 0,04340811 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01225598 0,04334342 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01225598 0,04327892 ! lymph node development GO:0048535 9 7 0,000 0,01225598 0,04321461 ! anterior/posterior axis specification GO:0009948 11 7 0,000 0,01225598 0,04315049 ! negative regulation of viral reproduction GO:0048525 9 7 0,000 0,01225598 0,04308657 ! regulation of T cell mediated cytotoxicity GO:0001914 15 7 0,000 0,01225598 0,04302283 ! positive regulation of glucose import GO:0046326 7 7 0,000 0,01225598 0,04295928 GO:0010828|positive regulation of glucose transport, ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01225598 0,04289592 ! ATP catabolic process GO:0006200 10 7 0,000 0,01225598 0,04283274 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01225598 0,04276975 ! positive regulation of fibrinolysis GO:0051919 8 7 0,000 0,01225598 0,04270695 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01225598 0,04264433 ! negative regulation of calcium ion transport GO:0051926 8 7 0,000 0,01225598 0,04258189 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01225598 0,04251964 ! positive regulation of blood vessel endothelial cell migration GO:0043536 17 7 0,000 0,01225598 0,04245757 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01225598 0,04239568 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01225598 0,04233396 ! muscle adaptation GO:0043500 12 7 0,000 0,01225598 0,04227243 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01225598 0,04221108 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 8 7 0,000 0,01225598 0,0421499 ! retina homeostasis GO:0001895 9 7 0,000 0,01225598 0,04208891 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01225598 0,04202808 ! regulation of growth hormone secretion GO:0060123 14 7 0,000 0,01225598 0,04196744 ! regulation of T cell receptor signaling pathway GO:0050856 12 7 0,000 0,01225598 0,04190696 ! positive regulation of microtubule polymerization GO:0031116 12 7 0,000 0,01225598 0,04184667 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01225598 0,04178654 ! polysaccharide metabolic process GO:0005976 141 98 1,000 0,01286557 0,04380201 ! Wnt receptor signaling pathway GO:0016055 161 98 1,000 0,01286557 0,04373925 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 8 0,000 0,01399488 0,0475105 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 16 8 0,000 0,01399488 0,04744263 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01399488 0,04737495 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! oligosaccharide biosynthetic process GO:0009312 14 8 0,000 0,01399488 0,04730746 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 8 0,000 0,01399488 0,04724017 ! negative regulation of cellular catabolic process GO:0031330 10 8 0,000 0,01399488 0,04717307 ! positive regulation of small GTPase mediated signal transduction GO:0051057 16 8 0,000 0,01399488 0,04710616 GO:0046579|positive regulation of Ras protein signal transduction, ! generation of neurons in the forebrain GO:0021872 11 8 0,000 0,01399488 0,04703943 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01399488 0,0469729 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01399488 0,04690655 ! neutral lipid catabolic process GO:0046461 11 8 0,000 0,01399488 0,04684039 ! N-glycan processing GO:0006491 12 8 0,000 0,01399488 0,04677442 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01399488 0,04670863 ! glycosaminoglycan catabolic process GO:0006027 11 8 0,000 0,01399488 0,04664303 ! negative regulation of JAK-STAT cascade GO:0046426 18 8 0,000 0,01399488 0,04657761 ! mRNA stabilization GO:0048255 16 8 0,000 0,01399488 0,04651238 GO:0043489|RNA stabilization, ! induction of positive chemotaxis GO:0050930 16 8 0,000 0,01399488 0,04644733 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01399488 0,04638246 ! lipoprotein transport GO:0042953 14 8 0,000 0,01399488 0,04631777 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01399488 0,04625326 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01399488 0,04618893 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01399488 0,04612478 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01399488 0,0460608 ! amyloid precursor protein catabolic process GO:0042987 13 8 0,000 0,01399488 0,04599701 ! bile acid and bile salt transport GO:0015721 12 8 0,000 0,01399488 0,04593339 ! ganglioside metabolic process GO:0001573 16 8 0,000 0,01399488 0,04586994 ! regulation of mesenchymal cell proliferation GO:0010464 12 8 0,000 0,01399488 0,04580668 ! reflex GO:0060004 16 8 0,000 0,01399488 0,04574358 ! positive regulation of isotype switching GO:0045830 16 8 0,000 0,01399488 0,04568066 GO:0045911|positive regulation of DNA recombination, ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01399488 0,04561791 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of interleukin-12 biosynthetic process GO:0045075 10 8 0,000 0,01399488 0,04555534 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01399488 0,04549293 ! glycerolipid catabolic process GO:0046503 11 8 0,000 0,01399488 0,0454307 ! positive regulation of chemokine biosynthetic process GO:0045080 9 8 0,000 0,01399488 0,04536863 ! hemoglobin metabolic process GO:0020027 12 8 0,000 0,01399488 0,04530674 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01399488 0,04524501 ! nerve growth factor receptor signaling pathway GO:0048011 12 8 0,000 0,01399488 0,04518346 ! insulin-like growth factor receptor signaling pathway GO:0048009 16 8 0,000 0,01399488 0,04512206 ! adrenal gland development GO:0030325 18 8 0,000 0,01399488 0,04506084 ! embryonic cranial skeleton morphogenesis GO:0048701 12 8 0,000 0,01399488 0,04499978 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01399488 0,04493889 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01399488 0,04487816 ! proline metabolic process GO:0006560 9 8 0,000 0,01399488 0,0448176 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01399488 0,0447572 ! regulation of interleukin-8 biosynthetic process GO:0045414 10 8 0,000 0,01399488 0,04469696 ! regulation of pigmentation during development GO:0048070 18 8 0,000 0,01399488 0,04463688 ! central nervous system neuron axonogenesis GO:0021955 16 8 0,000 0,01399488 0,04457697 GO:0021952|central nervous system projection neuron axonogenesis, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 15 8 0,000 0,01399488 0,04451721 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01399488 0,04445762 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01399488 0,04439818 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of activated T cell proliferation GO:0042104 19 8 0,000 0,01399488 0,0443389 ! galactose metabolic process GO:0006012 14 8 0,000 0,01399488 0,04427979 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01399488 0,04422082 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01399488 0,04416202 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01399488 0,04410337 ! neurotransmitter catabolic process GO:0042135 16 8 0,000 0,01399488 0,04404488 ! ruffle organization GO:0031529 12 8 0,000 0,01399488 0,04398654 ! osteoblast development GO:0002076 14 8 0,000 0,01399488 0,04392836 ! macroautophagy GO:0016236 14 8 0,000 0,01399488 0,04387033 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01399488 0,04381245 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01399488 0,04375473 ! regulation of Notch signaling pathway GO:0008593 22 8 0,000 0,01399488 0,04369716 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01399488 0,04363974 GO:0030204|chondroitin sulfate metabolic process, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 14 8 0,000 0,01399488 0,04358247 ! G1 DNA damage checkpoint GO:0031571 19 8 0,000 0,01399488 0,04352535 ! protein retention in ER lumen GO:0006621 16 8 0,000 0,01399488 0,04346838 ! cardiac muscle cell differentiation GO:0055007 12 8 0,000 0,01399488 0,04341155 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 8 0,000 0,01399488 0,04335488 ! regulation of circadian rhythm GO:0042752 13 8 0,000 0,01399488 0,04329836 ! pigment granule localization GO:0051875 14 8 0,000 0,01399488 0,04324198 ! positive regulation of cytokine production during immune response GO:0002720 12 8 0,000 0,01399488 0,04318575 ! antigen processing and presentation of endogenous antigen GO:0019883 14 8 0,000 0,01399488 0,04312966 ! response to tropane GO:0014073 14 8 0,000 0,01399488 0,04307372 GO:0042220|response to cocaine, ! positive regulation of systemic arterial blood pressure GO:0003084 12 8 0,000 0,01399488 0,04301793 ! embryonic axis specification GO:0000578 12 8 0,000 0,01399488 0,04296228 ! negative regulation of interferon-gamma production GO:0032689 12 8 0,000 0,01399488 0,04290677 ! negative regulation of systemic arterial blood pressure GO:0003085 18 8 0,000 0,01399488 0,04285141 ! sphingomyelin metabolic process GO:0006684 11 8 0,000 0,01399488 0,04279618 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01399488 0,04274111 GO:0016180|snRNA processing, ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 0,01399488 0,04268617 ! regulation of focal adhesion formation GO:0051893 17 8 0,000 0,01399488 0,04263137 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01399488 0,04257672 ! regulation of mitochondrial membrane potential GO:0051881 14 8 0,000 0,01399488 0,0425222 ! regulation of interleukin-10 production GO:0032653 12 8 0,000 0,01399488 0,04246783 ! positive regulation of monooxygenase activity GO:0032770 12 8 0,000 0,01399488 0,04241359 ! protein import into peroxisome matrix GO:0016558 15 8 0,000 0,01399488 0,04235949 ! establishment of nucleus localization GO:0040023 14 8 0,000 0,01399488 0,04230553 ! icosanoid secretion GO:0032309 12 8 0,000 0,01399488 0,0422517 GO:0050482|arachidonic acid secretion, ! intracellular lipid transport GO:0032365 14 8 0,000 0,01399488 0,04219802 ! regulation of transcription from RNA polymerase III promoter GO:0006359 11 8 0,000 0,01399488 0,04214447 ! negative regulation of oxidoreductase activity GO:0051354 13 8 0,000 0,01399488 0,04209105 ! positive regulation of interleukin-1 beta secretion GO:0050718 10 8 0,000 0,01399488 0,04203777 ! regulation of T-helper 1 type immune response GO:0002825 10 8 0,000 0,01399488 0,04198463 ! S phase GO:0051320 8 8 0,000 0,01399488 0,04193162 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 25 8 0,000 0,01399488 0,04187874 ! regulation of macrophage differentiation GO:0045649 15 8 0,000 0,01399488 0,04182599 ! negative regulation of osteoclast differentiation GO:0045671 12 8 0,000 0,01399488 0,04177338 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01399488 0,0417209 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 8 0,000 0,01399488 0,04166856 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01399488 0,04161634 ! melanin biosynthetic process GO:0042438 11 8 0,000 0,01399488 0,04156425 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01399488 0,0415123 ! regulation of synaptogenesis GO:0051963 12 8 0,000 0,01399488 0,04146047 ! hormone catabolic process GO:0042447 13 8 0,000 0,01399488 0,04140878 ! nicotinamide nucleotide biosynthetic process GO:0019359 12 8 0,000 0,01399488 0,04135721 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01399488 0,04130577 ! positive regulation of ATPase activity GO:0032781 16 8 0,000 0,01399488 0,04125446 ! trophectodermal cell differentiation GO:0001829 10 8 0,000 0,01399488 0,04120327 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01399488 0,04115222 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01399488 0,04110129 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01399488 0,04105048 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 0,01399488 0,0409998 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01399488 0,04094925 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01399488 0,04089882 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 0,01399488 0,04084851 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 8 0,000 0,01399488 0,04079833 ! negative regulation of B cell activation GO:0050869 17 8 0,000 0,01399488 0,04074827 ! behavioral response to nicotine GO:0035095 13 8 0,000 0,01399488 0,04069833 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01399488 0,04064852 GO:0000076|DNA replication checkpoint, ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 0,01399488 0,04059883 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 16 8 0,000 0,01399488 0,04054925 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 14 8 0,000 0,01399488 0,0404998 ! regulation of microtubule polymerization GO:0031113 14 8 0,000 0,01399488 0,04045047 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0157308 0,04541264 ! regulation of developmental growth GO:0048638 14 9 0,000 0,0157308 0,04535746 ! negative regulation of smooth muscle cell proliferation GO:0048662 15 9 0,000 0,0157308 0,04530241 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0157308 0,0452475 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 9 0,000 0,0157308 0,04519272 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 11 9 0,000 0,0157308 0,04513808 ! negative regulation of lipid biosynthetic process GO:0051055 13 9 0,000 0,0157308 0,04508356 ! glycerol-3-phosphate metabolic process GO:0006072 11 9 0,000 0,0157308 0,04502918 ! regulation of cellular amine metabolic process GO:0033238 12 9 0,000 0,0157308 0,04497493 ! cell volume homeostasis GO:0006884 14 9 0,000 0,0157308 0,0449208 ! regulation of epidermal growth factor receptor activity GO:0007176 14 9 0,000 0,0157308 0,04486681 GO:0010469|regulation of receptor activity, ! regulation of smooth muscle cell migration GO:0014910 22 9 0,000 0,0157308 0,04481295 ! UTP metabolic process GO:0046051 10 9 0,000 0,0157308 0,04475922 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 15 9 0,000 0,0157308 0,04470561 GO:0046457|prostanoid biosynthetic process, ! succinate metabolic process GO:0006105 16 9 0,000 0,0157308 0,04465214 ! smoothened signaling pathway GO:0007224 10 9 0,000 0,0157308 0,04459879 ! protein complex disassembly GO:0043241 17 9 0,000 0,0157308 0,04454557 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0157308 0,04449248 ! estrogen metabolic process GO:0008210 16 9 0,000 0,0157308 0,04443951 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0157308 0,04438667 ! cytoplasmic sequestering of transcription factor GO:0042994 12 9 0,000 0,0157308 0,04433395 ! negative regulation of muscle cell differentiation GO:0051148 10 9 0,000 0,0157308 0,04428136 ! T-helper 1 type immune response GO:0042088 13 9 0,000 0,0157308 0,0442289 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 22 9 0,000 0,0157308 0,04417655 ! lung alveolus development GO:0048286 18 9 0,000 0,0157308 0,04412434 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0157308 0,04407224 ! pseudouridine synthesis GO:0001522 10 9 0,000 0,0157308 0,04402027 ! endothelial cell differentiation GO:0045446 17 9 0,000 0,0157308 0,04396842 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0157308 0,04391669 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0157308 0,04386509 ! endoderm development GO:0007492 12 9 0,000 0,0157308 0,0438136 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0157308 0,04376224 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0157308 0,04371099 ! myeloid leukocyte mediated immunity GO:0002444 12 9 0,000 0,0157308 0,04365987 ! astrocyte differentiation GO:0048708 17 9 0,000 0,0157308 0,04360886 ! L-phenylalanine metabolic process GO:0006558 11 9 0,000 0,0157308 0,04355798 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 10 9 0,000 0,0157308 0,04350721 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0157308 0,04345656 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 13 9 0,000 0,0157308 0,04340603 ! reverse cholesterol transport GO:0043691 17 9 0,000 0,0157308 0,04335562 ! indolalkylamine metabolic process GO:0006586 15 9 0,000 0,0157308 0,04330532 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! melanin metabolic process GO:0006582 15 9 0,000 0,0157308 0,04325514 ! embryonic eye morphogenesis GO:0048048 15 9 0,000 0,0157308 0,04320508 ! macrophage activation GO:0042116 14 9 0,000 0,0157308 0,04315513 ! multicellular organism growth GO:0035264 16 9 0,000 0,0157308 0,0431053 ! retrograde transport, endosome to Golgi GO:0042147 14 9 0,000 0,0157308 0,04305558 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,0157308 0,04300598 ! neuron apoptosis GO:0051402 12 9 0,000 0,0157308 0,04295649 ! lens development in camera-type eye GO:0002088 11 9 0,000 0,0157308 0,04290711 ! positive regulation of vasodilation GO:0045909 14 9 0,000 0,0157308 0,04285785 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0157308 0,0428087 ! positive regulation of muscle contraction GO:0045933 13 9 0,000 0,0157308 0,04275967 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0157308 0,04271074 ! regulation of smoothened signaling pathway GO:0008589 15 9 0,000 0,0157308 0,04266193 ! Schwann cell differentiation GO:0014037 20 9 0,000 0,0157308 0,04261323 ! acyl-CoA metabolic process GO:0006637 14 9 0,000 0,0157308 0,04256464 ! regulation of gliogenesis GO:0014013 21 9 0,000 0,0157308 0,04251616 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 21 9 0,000 0,0157308 0,04246779 ! oligodendrocyte development GO:0014003 13 9 0,000 0,0157308 0,04241953 ! alpha-beta T cell differentiation GO:0046632 15 9 0,000 0,0157308 0,04237138 ! segment specification GO:0007379 11 9 0,000 0,0157308 0,04232334 ! cellular extravasation GO:0045123 12 9 0,000 0,0157308 0,04227541 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0157308 0,04222759 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 13 9 0,000 0,0157308 0,04217987 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0157308 0,04213227 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0157308 0,04208477 ! antigen processing and presentation of exogenous antigen GO:0019884 11 9 0,000 0,0157308 0,04203737 ! positive regulation of production of molecular mediator of immune response GO:0002702 13 9 0,000 0,0157308 0,04199009 ! purine nucleoside triphosphate catabolic process GO:0009146 13 9 0,000 0,0157308 0,04194291 ! regulation of T cell differentiation in the thymus GO:0033081 14 9 0,000 0,0157308 0,04189583 ! response to amine stimulus GO:0014075 13 9 0,000 0,0157308 0,04184887 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of protein kinase B signaling cascade GO:0051896 16 9 0,000 0,0157308 0,041802 ! erythrocyte development GO:0048821 13 9 0,000 0,0157308 0,04175524 ! renal water homeostasis GO:0003091 13 9 0,000 0,0157308 0,04170859 ! positive regulation of tumor necrosis factor production GO:0032760 10 9 0,000 0,0157308 0,04166204 ! nucleosome disassembly GO:0006337 13 9 0,000 0,0157308 0,04161559 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! spinal cord motor neuron differentiation GO:0021522 12 9 0,000 0,0157308 0,04156925 ! transcription from RNA polymerase I promoter GO:0006360 14 9 0,000 0,0157308 0,04152301 ! induction of an organ GO:0001759 13 9 0,000 0,0157308 0,04147688 ! leukocyte activation during immune response GO:0002366 15 9 0,000 0,0157308 0,04143084 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 11 9 0,000 0,0157308 0,04138491 ! cerebellum morphogenesis GO:0021587 13 9 0,000 0,0157308 0,04133908 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 11 9 0,000 0,0157308 0,04129335 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0157308 0,04124772 ! sterol catabolic process GO:0016127 11 9 0,000 0,0157308 0,04120219 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 18 9 0,000 0,0157308 0,04115677 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0157308 0,04111144 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 14 9 0,000 0,0157308 0,04106621 ! positive regulation of interleukin-1 secretion GO:0050716 11 9 0,000 0,0157308 0,04102109 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,0157308 0,04097606 ! negative regulation of cytokine secretion GO:0050710 13 9 0,000 0,0157308 0,04093113 ! prophase GO:0051324 12 9 0,000 0,0157308 0,0408863 ! neuroblast proliferation GO:0007405 19 9 0,000 0,0157308 0,04084156 ! peptidyl-threonine modification GO:0018210 22 9 0,000 0,0157308 0,04079693 ! regulation of interleukin-1 beta secretion GO:0050706 12 9 0,000 0,0157308 0,04075239 ! ubiquinone metabolic process GO:0006743 11 9 0,000 0,0157308 0,04070795 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of erythrocyte differentiation GO:0045648 20 9 0,000 0,0157308 0,0406636 ! acid secretion GO:0046717 14 9 0,000 0,0157308 0,04061936 ! purine base metabolic process GO:0006144 18 9 0,000 0,0157308 0,0405752 ! detection of calcium ion GO:0005513 13 9 0,000 0,0157308 0,04053115 ! myeloid cell homeostasis GO:0002262 10 9 0,000 0,0157308 0,04048719 ! regulation of fibrinolysis GO:0051917 14 9 0,000 0,0157308 0,04044332 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0157308 0,04039955 ! negative regulation of blood vessel endothelial cell migration GO:0043537 18 9 0,000 0,0157308 0,04035588 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0157308 0,0403123 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0157308 0,04026881 ! defense response to Gram-positive bacterium GO:0050830 11 9 0,000 0,0157308 0,04022542 ! prepulse inhibition GO:0060134 14 9 0,000 0,0157308 0,04018212 ! sequestering of metal ion GO:0051238 12 9 0,000 0,0157308 0,04013891 ! lamellipodium assembly GO:0030032 12 9 0,000 0,0157308 0,0400958 ! regulation of embryonic development GO:0045995 17 9 0,000 0,0157308 0,04005278 ! mitochondrion localization GO:0051646 15 9 0,000 0,0157308 0,04000985 ! localization within membrane GO:0051668 15 9 0,000 0,0157308 0,03996701 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01746376 0,04432245 ! axon extension GO:0048675 13 10 0,000 0,01746376 0,0442751 ! neuron fate specification GO:0048665 12 10 0,000 0,01746376 0,04422785 ! regulation of epithelial cell differentiation GO:0030856 20 10 0,000 0,01746376 0,04418069 ! cortical actin cytoskeleton organization GO:0030866 24 10 0,000 0,01746376 0,04413364 ! associative learning GO:0008306 19 10 0,000 0,01746376 0,04408669 ! cellular copper ion homeostasis GO:0006878 14 10 0,000 0,01746376 0,04403984 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01746376 0,04399309 ! CTP metabolic process GO:0046036 11 10 0,000 0,01746376 0,04394644 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 17 10 0,000 0,01746376 0,04389989 ! GTP metabolic process GO:0046039 11 10 0,000 0,01746376 0,04385343 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01746376 0,04380707 GO:0007520|myoblast fusion, ! actin-myosin filament sliding GO:0033275 14 10 0,000 0,01746376 0,04376081 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01746376 0,04371465 ! social behavior GO:0035176 15 10 0,000 0,01746376 0,04366859 ! sulfate transport GO:0008272 12 10 0,000 0,01746376 0,04362262 ! regulation of activated T cell proliferation GO:0046006 22 10 0,000 0,01746376 0,04357675 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 19 10 0,000 0,01746376 0,04353098 ! artery development GO:0060840 20 10 0,000 0,01746376 0,0434853 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 13 10 0,000 0,01746376 0,04343972 ! response to pain GO:0048265 20 10 0,000 0,01746376 0,04339423 ! COPI coating of Golgi vesicle GO:0048205 15 10 0,000 0,01746376 0,04334884 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,01746376 0,04330354 ! phospholipid efflux GO:0033700 17 10 0,000 0,01746376 0,04325834 ! hippocampus development GO:0021766 19 10 0,000 0,01746376 0,04321323 ! positive regulation of transcription factor import into nucleus GO:0042993 21 10 0,000 0,01746376 0,04316822 ! amyloid precursor protein metabolic process GO:0042982 16 10 0,000 0,01746376 0,0431233 ! blood vessel remodeling GO:0001974 23 10 0,000 0,01746376 0,04307847 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01746376 0,04303374 ! pathogenesis GO:0009405 13 10 0,000 0,01746376 0,0429891 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01746376 0,04294455 ! two-component signal transduction system (phosphorelay) GO:0000160 15 10 0,000 0,01746376 0,04290009 ! negative regulation of striated muscle development GO:0045843 13 10 0,000 0,01746376 0,04285573 ! protein targeting to ER GO:0045047 21 10 0,000 0,01746376 0,04281146 ! regulation of S phase of mitotic cell cycle GO:0007090 19 10 0,000 0,01746376 0,04276728 ! arginine catabolic process GO:0006527 12 10 0,000 0,01746376 0,04272319 ! melanocyte differentiation GO:0030318 16 10 0,000 0,01746376 0,04267919 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 14 10 0,000 0,01746376 0,04263528 GO:0010833|telomere maintenance via telomere lengthening, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01746376 0,04259146 ! regulation of phosphoprotein phosphatase activity GO:0043666 20 10 0,000 0,01746376 0,04254773 ! regulation of stress fiber formation GO:0051492 24 10 0,000 0,01746376 0,04250409 ! positive regulation of endothelial cell migration GO:0010595 20 10 0,000 0,01746376 0,04246054 ! B cell proliferation GO:0042100 16 10 0,000 0,01746376 0,04241708 ! nucleobase biosynthetic process GO:0046112 20 10 0,000 0,01746376 0,04237371 ! mannose metabolic process GO:0006013 11 10 0,000 0,01746376 0,04233043 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01746376 0,04228724 ! forebrain cell migration GO:0021885 17 10 0,000 0,01746376 0,04224413 ! lipid digestion GO:0044241 15 10 0,000 0,01746376 0,04220111 ! substrate-bound cell migration GO:0006929 11 10 0,000 0,01746376 0,04215818 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01746376 0,04211534 ! receptor clustering GO:0043113 18 10 0,000 0,01746376 0,04207258 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01746376 0,04202991 ! UV protection GO:0009650 14 10 0,000 0,01746376 0,04198733 ! entry into host cell GO:0030260 21 10 0,000 0,01746376 0,04194483 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipoprotein lipase activity GO:0051004 20 10 0,000 0,01746376 0,04190242 ! behavioral fear response GO:0001662 19 10 0,000 0,01746376 0,04186009 GO:0002209|behavioral defense response, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01746376 0,04181785 ! negative regulation of ossification GO:0030279 21 10 0,000 0,01746376 0,0417757 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 23 10 0,000 0,01746376 0,04173363 ! protein homotetramerization GO:0051289 20 10 0,000 0,01746376 0,04169164 ! positive regulation of peptide secretion GO:0002793 16 10 0,000 0,01746376 0,04164974 ! response to dsRNA GO:0043331 19 10 0,000 0,01746376 0,04160792 ! DNA ligation GO:0006266 16 10 0,000 0,01746376 0,04156619 ! phosphoinositide 3-kinase cascade GO:0014065 26 10 0,000 0,01746376 0,04152454 ! regulation of interleukin-4 production GO:0032673 18 10 0,000 0,01746376 0,04148297 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01746376 0,04144149 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01746376 0,04140009 ! positive regulation of Ras GTPase activity GO:0032320 24 10 0,000 0,01746376 0,04135877 ! postreplication repair GO:0006301 16 10 0,000 0,01746376 0,04131754 ! fucose catabolic process GO:0019317 17 10 0,000 0,01746376 0,04127639 GO:0042355|L-fucose catabolic process, ! mRNA cleavage GO:0006379 14 10 0,000 0,01746376 0,04123532 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01746376 0,04119433 ! hindbrain morphogenesis GO:0021575 16 10 0,000 0,01746376 0,04115342 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 10 0,000 0,01746376 0,04111259 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 13 10 0,000 0,01746376 0,04107185 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01746376 0,04103118 ! positive regulation of neuron differentiation GO:0045666 13 10 0,000 0,01746376 0,0409906 ! positive regulation of leukocyte migration GO:0002687 24 10 0,000 0,01746376 0,04095009 ! multicellular organismal water homeostasis GO:0050891 14 10 0,000 0,01746376 0,04090967 ! negative regulation of lymphocyte differentiation GO:0045620 13 10 0,000 0,01746376 0,04086932 ! methionine biosynthetic process GO:0009086 13 10 0,000 0,01746376 0,04082906 ! oocyte differentiation GO:0009994 14 10 0,000 0,01746376 0,04078887 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 14 10 0,000 0,01746376 0,04074876 ! spleen development GO:0048536 17 10 0,000 0,01746376 0,04070873 ! negative regulation of BMP signaling pathway GO:0030514 15 10 0,000 0,01746376 0,04066878 ! regulation of RNA splicing GO:0043484 15 10 0,000 0,01746376 0,04062891 ! positive regulation of viral reproduction GO:0048524 14 10 0,000 0,01746376 0,04058912 ! blastocyst formation GO:0001825 14 10 0,000 0,01746376 0,0405494 ! embryonic gut development GO:0048566 13 10 0,000 0,01746376 0,04050977 ! quinone cofactor metabolic process GO:0042375 12 10 0,000 0,01746376 0,04047021 ! cerebellar cortex development GO:0021695 14 10 0,000 0,01746376 0,04043072 ! activation of innate immune response GO:0002218 10 10 0,000 0,01746376 0,04039132 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01746376 0,04035199 ! insulin secretion GO:0030073 18 10 0,000 0,01746376 0,04031274 ! cytoplasmic sequestering of protein GO:0051220 15 10 0,000 0,01746376 0,04027356 ! response to nicotine GO:0035094 18 10 0,000 0,01746376 0,04023446 ! nucleus localization GO:0051647 16 10 0,000 0,01746376 0,04019543 ! regulation of synapse organization GO:0050807 14 10 0,000 0,01746376 0,04015648 ! negative regulation of muscle development GO:0048635 14 11 0,000 0,01919375 0,04409173 ! positive regulation of glucose metabolic process GO:0010907 17 11 0,000 0,01919375 0,04404909 ! ER-associated protein catabolic process GO:0030433 17 11 0,000 0,01919375 0,04400653 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of blood pressure GO:0045776 25 11 0,000 0,01919375 0,04396406 ! cortical cytoskeleton organization GO:0030865 25 11 0,000 0,01919375 0,04392166 ! virus-host interaction GO:0019048 20 11 0,000 0,01919375 0,04387935 ! thyroid gland development GO:0030878 20 11 0,000 0,01919375 0,04383711 ! pentose-phosphate shunt GO:0006098 14 11 0,000 0,01919375 0,04379496 GO:0006740|NADPH regeneration, ! regulation of phosphatase activity GO:0010921 23 11 0,000 0,01919375 0,04375289 ! non-recombinational repair GO:0000726 19 11 0,000 0,01919375 0,0437109 GO:0006303|double-strand break repair via nonhomologous end joining, ! synapsis GO:0007129 15 11 0,000 0,01919375 0,04366899 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 11 11 0,000 0,01919375 0,04362717 ! elastic fiber assembly GO:0048251 17 11 0,000 0,01919375 0,04358542 ! regulation of positive chemotaxis GO:0050926 19 11 0,000 0,01919375 0,04354375 GO:0050927|positive regulation of positive chemotaxis, ! regulation of glycolysis GO:0006110 18 11 0,000 0,01919375 0,04350216 ! dopamine receptor signaling pathway GO:0007212 25 11 0,000 0,01919375 0,04346065 ! regulation of cell projection assembly GO:0060491 22 11 0,000 0,01919375 0,04341922 ! positive regulation of lipid metabolic process GO:0045834 15 11 0,000 0,01919375 0,04337787 ! bone resorption GO:0045453 16 11 0,000 0,01919375 0,04333659 ! regulation of chemokine biosynthetic process GO:0045073 13 11 0,000 0,01919375 0,0432954 ! peptide or protein amino-terminal blocking GO:0018409 16 11 0,000 0,01919375 0,04325428 ! ventral spinal cord development GO:0021517 15 11 0,000 0,01919375 0,04321325 ! regulated secretory pathway GO:0045055 15 11 0,000 0,01919375 0,04317229 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 19 11 0,000 0,01919375 0,0431314 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of catecholamine secretion GO:0050433 21 11 0,000 0,01919375 0,0430906 ! syncytium formation GO:0006949 15 11 0,000 0,01919375 0,04304987 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01919375 0,04300922 ! glucan biosynthetic process GO:0009250 14 11 0,000 0,01919375 0,04296864 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 16 11 0,000 0,01919375 0,04292814 ! Golgi organization GO:0007030 19 11 0,000 0,01919375 0,04288772 ! response to X-ray GO:0010165 19 11 0,000 0,01919375 0,04284738 ! retinoic acid receptor signaling pathway GO:0048384 16 11 0,000 0,01919375 0,04280711 ! adult heart development GO:0007512 12 11 0,000 0,01919375 0,04276691 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01919375 0,04272679 ! epithelial cell development GO:0002064 16 11 0,000 0,01919375 0,04268675 ! actin cytoskeleton reorganization GO:0031532 20 11 0,000 0,01919375 0,04264678 ! temperature homeostasis GO:0001659 16 11 0,000 0,01919375 0,04260689 ! L-glutamate transport GO:0015813 15 11 0,000 0,01919375 0,04256707 GO:0015800|acidic amino acid transport, ! positive regulation vascular endothelial growth factor production GO:0010575 19 11 0,000 0,01919375 0,04252732 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01919375 0,04248765 ! motor axon guidance GO:0008045 17 11 0,000 0,01919375 0,04244805 ! copper ion homeostasis GO:0055070 15 11 0,000 0,01919375 0,04240853 ! protein targeting to peroxisome GO:0006625 21 11 0,000 0,01919375 0,04236908 ! regulation of bone resorption GO:0045124 27 11 0,000 0,01919375 0,0423297 ! stem cell development GO:0048864 30 11 0,000 0,01919375 0,0422904 GO:0019827|stem cell maintenance, ! alpha-beta T cell activation GO:0046631 18 11 0,000 0,01919375 0,04225117 ! negative regulation of axonogenesis GO:0050771 26 11 0,000 0,01919375 0,04221201 ! regulation of phagocytosis GO:0050764 16 11 0,000 0,01919375 0,04217293 ! regulation of insulin receptor signaling pathway GO:0046626 17 11 0,000 0,01919375 0,04213391 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01919375 0,04209497 ! nucleoside triphosphate catabolic process GO:0009143 16 11 0,000 0,01919375 0,0420561 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01919375 0,04201731 ! synaptic vesicle exocytosis GO:0016079 16 11 0,000 0,01919375 0,04197858 ! regulation of B cell differentiation GO:0045577 23 11 0,000 0,01919375 0,04193993 ! cranial nerve development GO:0021545 14 11 0,000 0,01919375 0,04190134 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01919375 0,04186283 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01919375 0,04182439 ! salivary gland development GO:0007431 24 11 0,000 0,01919375 0,04178602 ! negative regulation of neurological system process GO:0031645 20 11 0,000 0,01919375 0,04174772 ! regulation of leukocyte migration GO:0002685 25 11 0,000 0,01919375 0,04170949 ! musculoskeletal movement GO:0050881 16 11 0,000 0,01919375 0,04167133 GO:0050879|multicellular organismal movement, ! nitric oxide mediated signal transduction GO:0007263 20 11 0,000 0,01919375 0,04163324 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01919375 0,04159522 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01919375 0,04155726 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 19 11 0,000 0,01919375 0,04151938 ! cholesterol efflux GO:0033344 20 11 0,000 0,01919375 0,04148157 ! digestive tract morphogenesis GO:0048546 16 11 0,000 0,01919375 0,04144382 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 11 0,000 0,01919375 0,04140615 ! thyroid hormone metabolic process GO:0042403 17 11 0,000 0,01919375 0,04136854 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01919375 0,041331 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 21 11 0,000 0,01919375 0,04129353 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01919375 0,04125612 ! regulation of actin filament bundle formation GO:0032231 25 11 0,000 0,01919375 0,04121879 ! cardiac cell differentiation GO:0035051 18 11 0,000 0,01919375 0,04118152 ! defense response to fungus GO:0050832 13 11 0,000 0,01919375 0,04114432 ! lysogeny GO:0030069 20 11 0,000 0,01919375 0,04110719 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 22 11 0,000 0,01919375 0,04107012 ! acrosome reaction GO:0007340 14 11 0,000 0,01919375 0,04103312 ! regulation of synapse structure and activity GO:0050803 15 11 0,000 0,01919375 0,04099618 ! regulation of steroid biosynthetic process GO:0050810 13 11 0,000 0,01919375 0,04095932 ! rRNA transcription GO:0009303 19 12 0,000 0,02092078 0,04460468 ! reproductive cellular process GO:0048610 15 12 0,000 0,02092078 0,04456464 ! regulation of membrane protein ectodomain proteolysis GO:0051043 17 12 0,000 0,02092078 0,04452467 ! pteridine and derivative biosynthetic process GO:0042559 15 12 0,000 0,02092078 0,04448477 ! dicarboxylic acid transport GO:0006835 21 12 0,000 0,02092078 0,04444495 ! phosphate transport GO:0006817 15 12 0,000 0,02092078 0,0444052 ! positive regulation of GTPase activity GO:0043547 29 12 0,000 0,02092078 0,04436551 ! peroxisomal transport GO:0043574 22 12 0,000 0,02092078 0,0443259 ! mating GO:0007618 16 12 0,000 0,02092078 0,04428636 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02092078 0,04424689 ! heart looping GO:0001947 15 12 0,000 0,02092078 0,04420749 ! negative regulation of cell-matrix adhesion GO:0001953 31 12 0,000 0,02092078 0,04416816 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 20 12 0,000 0,02092078 0,0441289 ! negative regulation of proteolysis GO:0045861 17 12 0,000 0,02092078 0,04408971 ! T cell selection GO:0045058 25 12 0,000 0,02092078 0,04405058 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02092078 0,04401153 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 17 12 0,000 0,02092078 0,04397255 ! oligodendrocyte differentiation GO:0048709 19 12 0,000 0,02092078 0,04393364 ! plasma membrane organization GO:0007009 19 12 0,000 0,02092078 0,04389479 ! focal adhesion formation GO:0048041 28 12 0,000 0,02092078 0,04385601 ! mitotic spindle organization GO:0007052 16 12 0,000 0,02092078 0,04381731 ! regulation of intracellular pH GO:0051453 19 12 0,000 0,02092078 0,04377867 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02092078 0,0437401 ! monoamine transport GO:0015844 14 12 0,000 0,02092078 0,04370159 ! regulation of vascular endothelial growth factor production GO:0010574 20 12 0,000 0,02092078 0,04366316 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 18 12 0,000 0,02092078 0,04362479 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02092078 0,04358649 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02092078 0,04354825 ! regulation of organ growth GO:0046620 14 12 0,000 0,02092078 0,04351009 ! vasoconstriction GO:0042310 18 12 0,000 0,02092078 0,04347199 ! RNA-dependent DNA replication GO:0006278 16 12 0,000 0,02092078 0,04343395 ! regulation of interleukin-8 production GO:0032677 19 12 0,000 0,02092078 0,04339599 ! regulation of Rho GTPase activity GO:0032319 22 12 0,000 0,02092078 0,04335809 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02092078 0,04332025 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02092078 0,04328248 ! histone deacetylation GO:0016575 14 12 0,000 0,02092078 0,04324478 ! histone acetylation GO:0016573 27 12 0,000 0,02092078 0,04320714 ! DNA methylation GO:0006306 19 12 0,000 0,02092078 0,04316957 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 19 12 0,000 0,02092078 0,04313207 ! protein sumoylation GO:0016925 14 12 0,000 0,02092078 0,04309463 ! chromatin silencing GO:0006342 23 12 0,000 0,02092078 0,04305725 ! negative regulation of MAPKKK cascade GO:0043409 23 12 0,000 0,02092078 0,04301994 ! gland morphogenesis GO:0022612 24 12 0,000 0,02092078 0,04298269 ! regulation of hormone metabolic process GO:0032350 21 12 0,000 0,02092078 0,04294551 ! zymogen activation GO:0031638 16 12 0,000 0,02092078 0,04290839 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02092078 0,04287134 ! nucleosome positioning GO:0016584 13 12 0,000 0,02092078 0,04283435 ! T cell homeostasis GO:0043029 22 12 0,000 0,02092078 0,04279742 ! regulation of isotype switching GO:0045191 22 12 0,000 0,02092078 0,04276056 ! glutathione biosynthetic process GO:0006750 14 12 0,000 0,02092078 0,04272376 ! response to gamma radiation GO:0010332 21 12 0,000 0,02092078 0,04268702 ! regulation of osteoclast differentiation GO:0045670 18 12 0,000 0,02092078 0,04265035 ! regulation of T-helper 2 cell differentiation GO:0045628 19 12 0,000 0,02092078 0,04261374 ! aromatic amino acid family catabolic process GO:0009074 16 12 0,000 0,02092078 0,04257719 ! serine family amino acid biosynthetic process GO:0009070 16 12 0,000 0,02092078 0,04254071 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02092078 0,04250429 ! male genitalia development GO:0030539 15 12 0,000 0,02092078 0,04246793 ! regulation of cellular carbohydrate catabolic process GO:0043471 19 12 0,000 0,02092078 0,04243163 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fatty acid oxidation GO:0046320 20 12 0,000 0,02092078 0,0423954 ! developmental induction GO:0031128 16 12 0,000 0,02092078 0,04235922 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 15 12 0,000 0,02092078 0,04232311 ! response to cold GO:0009409 15 12 0,000 0,02092078 0,04228706 ! negative regulation of immune effector process GO:0002698 20 12 0,000 0,02092078 0,04225107 ! respiratory burst GO:0045730 22 13 0,000 0,02264486 0,04569409 ! lactation GO:0007595 22 13 0,000 0,02264486 0,04565526 ! tRNA modification GO:0006400 15 13 0,000 0,02264486 0,04561651 ! negative regulation of cell projection organization GO:0031345 29 13 0,000 0,02264486 0,04557782 ! positive regulation of blood pressure GO:0045777 19 13 0,000 0,02264486 0,04553919 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02264486 0,04550063 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 20 13 0,000 0,02264486 0,04546214 ! water transport GO:0006833 21 13 0,000 0,02264486 0,04542371 GO:0042044|fluid transport, ! regulation of nitric-oxide synthase activity GO:0050999 23 13 0,000 0,02264486 0,04538534 ! copper ion transport GO:0006825 15 13 0,000 0,02264486 0,04534704 ! filopodium assembly GO:0046847 21 13 0,000 0,02264486 0,04530881 ! lipid localization GO:0010876 25 13 0,000 0,02264486 0,04527064 GO:0019915|lipid storage, ! detection of mechanical stimulus GO:0050982 17 13 0,000 0,02264486 0,04523253 ! negative regulation of transcription factor import into nucleus GO:0042992 26 13 0,000 0,02264486 0,04519449 ! cytokine biosynthetic process GO:0042089 17 13 0,000 0,02264486 0,04515651 ! T cell proliferation GO:0042098 24 13 0,000 0,02264486 0,04511859 ! organelle fusion GO:0048284 29 13 0,000 0,02264486 0,04508074 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02264486 0,04504296 ! endocrine pancreas development GO:0031018 19 13 0,000 0,02264486 0,04500523 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 24 13 0,000 0,02264486 0,04496757 ! platelet-derived growth factor receptor signaling pathway GO:0048008 20 13 0,000 0,02264486 0,04492997 ! photoreceptor cell maintenance GO:0045494 20 13 0,000 0,02264486 0,04489244 ! regulation of mRNA processing GO:0050684 21 13 0,000 0,02264486 0,04485496 ! regulation of skeletal muscle fiber development GO:0048742 22 13 0,000 0,02264486 0,04481755 ! methionine metabolic process GO:0006555 16 13 0,000 0,02264486 0,0447802 ! deoxyribonucleotide catabolic process GO:0009264 17 13 0,000 0,02264486 0,04474292 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02264486 0,0447057 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 21 13 0,000 0,02264486 0,04466853 ! negative regulation of endothelial cell migration GO:0010596 22 13 0,000 0,02264486 0,04463143 ! membrane protein proteolysis GO:0033619 21 13 0,000 0,02264486 0,04459439 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 22 13 0,000 0,02264486 0,04455742 ! neutral amino acid transport GO:0015804 20 13 0,000 0,02264486 0,0445205 ! negative regulation of mitotic cell cycle GO:0045930 32 13 0,000 0,02264486 0,04448365 ! regulation of natural killer cell mediated immunity GO:0002715 21 13 0,000 0,02264486 0,04444685 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 16 13 0,000 0,02264486 0,04441012 ! positive regulation of protein import into nucleus GO:0042307 24 13 0,000 0,02264486 0,04437345 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02264486 0,04433684 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02264486 0,04430028 ! cellular pigmentation GO:0033059 24 13 0,000 0,02264486 0,04426379 ! histone methylation GO:0016571 16 13 0,000 0,02264486 0,04422736 ! regulation of epidermis development GO:0045682 21 13 0,000 0,02264486 0,04419099 ! oxygen transport GO:0015671 20 13 0,000 0,02264486 0,04415468 ! regulation of axon extension GO:0030516 26 13 0,000 0,02264486 0,04411843 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 24 13 0,000 0,02264486 0,04408224 ! detection of bacterium GO:0016045 13 13 0,000 0,02264486 0,0440461 ! L-fucose metabolic process GO:0042354 21 13 0,000 0,02264486 0,04401003 ! regulation of NF-kappaB import into nucleus GO:0042345 24 13 0,000 0,02264486 0,04397401 ! positive regulation of homeostatic process GO:0032846 19 13 0,000 0,02264486 0,04393806 ! positive regulation of protein polymerization GO:0032273 21 13 0,000 0,02264486 0,04390216 ! actin filament polymerization GO:0030041 18 13 0,000 0,02264486 0,04386632 ! regulation of protein ubiquitination GO:0031396 20 14 0,000 0,02436599 0,0471619 ! N-terminal protein amino acid modification GO:0031365 20 14 0,000 0,02436599 0,04712346 ! positive regulation of cellular catabolic process GO:0031331 24 14 0,000 0,02436599 0,04708508 ! G1 phase of mitotic cell cycle GO:0000080 24 14 0,000 0,02436599 0,04704677 ! neuron maturation GO:0042551 24 14 0,000 0,02436599 0,04700852 ! regulation of S phase GO:0033261 25 14 0,000 0,02436599 0,04697034 ! regulation of chemokine production GO:0032642 18 14 0,000 0,02436599 0,04693221 ! myotube differentiation GO:0014902 21 14 0,000 0,02436599 0,04689415 ! double-strand break repair via homologous recombination GO:0000724 24 14 0,000 0,02436599 0,04685615 GO:0000725|recombinational repair, ! negative regulation of bone remodeling GO:0046851 28 14 0,000 0,02436599 0,04681821 ! phospholipid catabolic process GO:0009395 19 14 0,000 0,02436599 0,04678033 ! aminoglycan catabolic process GO:0006026 19 14 0,000 0,02436599 0,04674251 ! vesicle targeting, to, from or within Golgi GO:0048199 19 14 0,000 0,02436599 0,04670475 ! cardiac muscle contraction GO:0060048 28 14 0,000 0,02436599 0,04666706 ! RNA polyadenylation GO:0043631 21 14 0,000 0,02436599 0,04662942 ! cartilage condensation GO:0001502 22 14 0,000 0,02436599 0,04659185 ! gene silencing by RNA GO:0031047 22 14 0,000 0,02436599 0,04655433 ! response to cAMP GO:0051591 20 14 0,000 0,02436599 0,04651688 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 17 14 0,000 0,02436599 0,04647949 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 14 0,000 0,02436599 0,04644216 ! negative regulation of cytokine biosynthetic process GO:0042036 19 14 0,000 0,02436599 0,04640488 ! limbic system development GO:0021761 25 14 0,000 0,02436599 0,04636767 ! positive regulation of ion transport GO:0043270 18 14 0,000 0,02436599 0,04633052 GO:0051928|positive regulation of calcium ion transport, ! startle response GO:0001964 21 14 0,000 0,02436599 0,04629342 ! palate development GO:0060021 19 14 0,000 0,02436599 0,04625639 ! negative regulation of gene expression, epigenetic GO:0045814 30 14 0,000 0,02436599 0,04621941 ! negative regulation of protein amino acid phosphorylation GO:0001933 31 14 0,000 0,02436599 0,04618249 ! regulation of defense response to virus GO:0050688 26 14 0,000 0,02436599 0,04614564 ! response to hexose stimulus GO:0009746 22 14 0,000 0,02436599 0,04610884 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! epidermis morphogenesis GO:0048730 31 14 0,000 0,02436599 0,0460721 ! arginine metabolic process GO:0006525 17 14 0,000 0,02436599 0,04603542 ! glutamate metabolic process GO:0006536 21 14 0,000 0,02436599 0,04599879 ! glycine metabolic process GO:0006544 22 14 0,000 0,02436599 0,04596223 ! pituitary gland development GO:0021983 24 14 0,000 0,02436599 0,04592572 ! tyrosine metabolic process GO:0006570 20 14 0,000 0,02436599 0,04588927 ! negative regulation of microtubule depolymerization GO:0007026 34 14 0,000 0,02436599 0,04585288 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 21 14 0,000 0,02436599 0,04581655 ! cytokine metabolic process GO:0042107 18 14 0,000 0,02436599 0,04578027 ! NAD metabolic process GO:0019674 25 14 0,000 0,02436599 0,04574405 ! regulation of ion transmembrane transporter activity GO:0032412 19 14 0,000 0,02436599 0,04570789 ! regulation of heart rate GO:0002027 26 14 0,000 0,02436599 0,04567179 ! exocrine system development GO:0035272 29 14 0,000 0,02436599 0,04563574 ! positive regulation of carbohydrate metabolic process GO:0045913 22 14 0,000 0,02436599 0,04559975 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside monophosphate metabolic process GO:0009126 22 14 0,000 0,02436599 0,04556382 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 25 14 0,000 0,02436599 0,04552794 ! axon cargo transport GO:0008088 29 14 0,000 0,02436599 0,04549212 ! positive regulation of T cell mediated immunity GO:0002711 30 14 0,000 0,02436599 0,04545636 ! negative regulation of protein import into nucleus GO:0042308 27 14 0,000 0,02436599 0,04542065 ! genitalia development GO:0048806 18 14 0,000 0,02436599 0,04538499 ! regulation of interleukin-12 production GO:0032655 20 14 0,000 0,02436599 0,0453494 ! autonomic nervous system development GO:0048483 26 14 0,000 0,02436599 0,04531386 ! tissue regeneration GO:0042246 24 14 0,000 0,02436599 0,04527837 ! negative regulation of protein secretion GO:0050709 22 14 0,000 0,02436599 0,04524294 ! water homeostasis GO:0030104 23 14 0,000 0,02436599 0,04520757 ! cofactor transport GO:0051181 22 14 0,000 0,02436599 0,04517225 ! regulation of acute inflammatory response GO:0002673 21 14 0,000 0,02436599 0,04513699 ! positive regulation of T-helper cell differentiation GO:0045624 20 14 0,000 0,02436599 0,04510178 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,02436599 0,04506663 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02436599 0,04503153 ! regulation of mRNA stability GO:0043488 30 14 0,000 0,02436599 0,04499649 ! positive regulation of JNK cascade GO:0046330 22 14 0,000 0,02436599 0,0449615 ! epithelial to mesenchymal transition GO:0001837 24 14 0,000 0,02436599 0,04492656 ! negative regulation of mast cell proliferation GO:0070667 26 14 0,000 0,02436599 0,04489168 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 21 14 0,000 0,02436599 0,04485685 ! microspike assembly GO:0030035 25 14 0,000 0,02436599 0,04482208 ! positive regulation of calcium-mediated signaling GO:0050850 27 14 0,000 0,02436599 0,04478736 ! regulation of skeletal muscle tissue development GO:0048641 24 15 0,000 0,02608417 0,04790846 ! superoxide anion generation GO:0042554 19 15 0,000 0,02608417 0,04787141 ! negative regulation of hormone secretion GO:0046888 22 15 0,000 0,02608417 0,04783442 ! embryonic hindlimb morphogenesis GO:0035116 28 15 0,000 0,02608417 0,04779748 ! embryonic forelimb morphogenesis GO:0035115 18 15 0,000 0,02608417 0,0477606 ! inositol metabolic process GO:0006020 21 15 0,000 0,02608417 0,04772377 ! retina development in camera-type eye GO:0060041 22 15 0,000 0,02608417 0,04768701 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 22 15 0,000 0,02608417 0,0476503 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 25 15 0,000 0,02608417 0,04761364 ! regulation of transmembrane transporter activity GO:0022898 20 15 0,000 0,02608417 0,04757704 GO:0032409|regulation of transporter activity, ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02608417 0,0475405 ! activation of MAPKK activity GO:0000186 22 15 0,000 0,02608417 0,04750402 ! induction of apoptosis via death domain receptors GO:0008625 19 15 0,000 0,02608417 0,04746759 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 18 15 0,000 0,02608417 0,04743121 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02608417 0,0473949 ! response to osmotic stress GO:0006970 23 15 0,000 0,02608417 0,04735863 ! vesicle coating GO:0006901 26 15 0,000 0,02608417 0,04732243 ! regulation of the force of heart contraction GO:0002026 24 15 0,000 0,02608417 0,04728628 ! preassembly of GPI anchor in ER membrane GO:0016254 22 15 0,000 0,02608417 0,04725018 ! positive regulation of activation of JAK2 kinase activity GO:0010535 15 15 0,000 0,02608417 0,04721414 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 23 15 0,000 0,02608417 0,04717815 ! bone mineralization GO:0030282 17 15 0,000 0,02608417 0,04714222 ! G1/S transition checkpoint GO:0031575 36 15 0,000 0,02608417 0,04710634 ! intermediate filament cytoskeleton organization GO:0045104 27 15 0,000 0,02608417 0,04707052 ! positive regulation of axonogenesis GO:0050772 21 15 0,000 0,02608417 0,04703475 ! regulation of cytokine production during immune response GO:0002718 23 15 0,000 0,02608417 0,04699904 ! T cell differentiation in the thymus GO:0033077 30 15 0,000 0,02608417 0,04696338 ! regulation of cellular pH GO:0030641 23 15 0,000 0,02608417 0,04692777 ! ribosome assembly GO:0042255 17 15 0,000 0,02608417 0,04689222 ! cerebellum development GO:0021549 19 15 0,000 0,02608417 0,04685673 ! regulation of monooxygenase activity GO:0032768 29 15 0,000 0,02608417 0,04682128 ! mRNA splice site selection GO:0006376 33 15 0,000 0,02608417 0,04678589 ! positive regulation of cytokine secretion GO:0050715 19 15 0,000 0,02608417 0,04675055 ! regulation of T-helper 2 type immune response GO:0002828 24 15 0,000 0,02608417 0,04671527 ! negative regulation of inflammatory response GO:0050728 18 15 0,000 0,02608417 0,04668004 ! sphingolipid catabolic process GO:0030149 27 15 0,000 0,02608417 0,04664486 GO:0046466|membrane lipid catabolic process, ! positive regulation of bone mineralization GO:0030501 22 15 0,000 0,02608417 0,04660974 ! regulation of erythrocyte differentiation GO:0045646 29 15 0,000 0,02608417 0,04657467 ! muscle maintenance GO:0046716 21 15 0,000 0,02608417 0,04653965 ! C21-steroid hormone biosynthetic process GO:0006700 17 15 0,000 0,02608417 0,04650468 ! activation of NF-kappaB-inducing kinase activity GO:0007250 23 15 0,000 0,02608417 0,04646977 ! intestinal absorption GO:0050892 22 15 0,000 0,02608417 0,04643491 ! regulation of ATPase activity GO:0043462 24 15 0,000 0,02608417 0,0464001 ! dopamine metabolic process GO:0042417 32 15 0,000 0,02608417 0,04636534 ! gas transport GO:0015669 23 15 0,000 0,02608417 0,04633064 ! regulation of RNA stability GO:0043487 31 15 0,000 0,02608417 0,04629599 ! organic cation transport GO:0015695 19 15 0,000 0,02608417 0,04626139 ! heme biosynthetic process GO:0006783 22 15 0,000 0,02608417 0,04622684 ! regulation of BMP signaling pathway GO:0030510 24 15 0,000 0,02608417 0,04619234 ! lymphocyte homeostasis GO:0002260 29 15 0,000 0,02608417 0,04615789 ! aromatic compound biosynthetic process GO:0019438 18 15 0,000 0,02608417 0,0461235 ! cilium assembly GO:0042384 22 15 0,000 0,02608417 0,04608915 ! regulation of calcium-mediated signaling GO:0050848 28 15 0,000 0,02608417 0,04605486 ! inner ear receptor cell differentiation GO:0060113 30 15 0,000 0,02608417 0,04602062 ! peptide hormone processing GO:0016486 23 15 0,000 0,02608417 0,04598643 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 36 15 0,000 0,02608417 0,04595229 ! sulfur amino acid biosynthetic process GO:0000097 21 16 0,000 0,02779941 0,04893769 ! bone remodeling GO:0046849 24 16 0,000 0,02779941 0,04890142 ! negative regulation of nucleocytoplasmic transport GO:0046823 29 16 0,000 0,02779941 0,04886519 ! positive regulation of nucleocytoplasmic transport GO:0046824 28 16 0,000 0,02779941 0,04882902 ! regulation of cell-cell adhesion GO:0022407 38 16 0,000 0,02779941 0,04879291 ! bile acid metabolic process GO:0008206 23 16 0,000 0,02779941 0,04875684 ! axis specification GO:0009798 26 16 0,000 0,02779941 0,04872083 ! negative regulation of endothelial cell proliferation GO:0001937 33 16 0,000 0,02779941 0,04868488 ! mitotic chromosome condensation GO:0007076 26 16 0,000 0,02779941 0,04864897 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02779941 0,04861312 ! centrosome cycle GO:0007098 18 16 0,000 0,02779941 0,04857733 ! cell differentiation in spinal cord GO:0021515 24 16 0,000 0,02779941 0,04854158 ! regulation of survival gene product expression GO:0045884 23 16 0,000 0,02779941 0,04850589 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 16 0,000 0,02779941 0,04847025 ! cellular response to starvation GO:0009267 26 16 0,000 0,02779941 0,04843466 ! DNA integration GO:0015074 25 16 0,000 0,02779941 0,04839913 ! branching involved in ureteric bud morphogenesis GO:0001658 24 16 0,000 0,02779941 0,04836364 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 35 16 0,000 0,02779941 0,04832821 ! regulation of exocytosis GO:0017157 28 16 0,000 0,02779941 0,04829283 ! embryonic digit morphogenesis GO:0042733 20 16 0,000 0,02779941 0,04825751 ! positive regulation of biomineral formation GO:0070169 23 16 0,000 0,02779941 0,04822223 ! regulation of vasodilation GO:0042312 26 16 0,000 0,02779941 0,048187 ! DNA replication initiation GO:0006270 26 16 0,000 0,02779941 0,04815183 ! DNA unwinding during replication GO:0006268 24 16 0,000 0,02779941 0,04811671 ! regulation of steroid metabolic process GO:0019218 23 16 0,000 0,02779941 0,04808164 ! neuron recognition GO:0008038 27 16 0,000 0,02779941 0,04804662 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 22 16 0,000 0,02779941 0,04801165 ! DNA fragmentation involved in apoptosis GO:0006309 20 16 0,000 0,02779941 0,04797673 ! G1 phase GO:0051318 28 16 0,000 0,02779941 0,04794187 ! cellular amino acid derivative catabolic process GO:0042219 31 16 0,000 0,02779941 0,04790705 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02779941 0,04787229 GO:0006626|protein targeting to mitochondrion, ! positive regulation of oxidoreductase activity GO:0051353 22 16 0,000 0,02779941 0,04783757 ! negative regulation of blood coagulation GO:0030195 21 16 0,000 0,02779941 0,04780291 ! negative regulation of tissue remodeling GO:0034104 35 16 0,000 0,02779941 0,04776829 ! NADP metabolic process GO:0006739 22 16 0,000 0,02779941 0,04773373 ! neuromuscular synaptic transmission GO:0007274 31 16 0,000 0,02779941 0,04769921 ! synaptic transmission, cholinergic GO:0007271 24 16 0,000 0,02779941 0,04766475 ! folic acid and derivative metabolic process GO:0006760 18 16 0,000 0,02779941 0,04763033 ! regulation of T-helper cell differentiation GO:0045622 25 16 0,000 0,02779941 0,04759597 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02779941 0,04756165 ! aspartate family amino acid biosynthetic process GO:0009067 19 16 0,000 0,02779941 0,04752738 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 24 16 0,000 0,02779941 0,04749317 ! positive regulation of neuron apoptosis GO:0043525 30 16 0,000 0,02779941 0,047459 ! regulation of blood vessel endothelial cell migration GO:0043535 37 16 0,000 0,02779941 0,04742488 ! RNA 3'-end processing GO:0031123 23 16 0,000 0,02779941 0,04739081 ! defense response to virus GO:0051607 28 16 0,000 0,02779941 0,04735679 ! peptide hormone secretion GO:0030072 26 16 0,000 0,02779941 0,04732282 ! positive regulation of protein complex assembly GO:0031334 26 17 0,000 0,02951172 0,05020166 ! regulation of lipid biosynthetic process GO:0046890 22 17 0,000 0,02951172 0,0501657 ! negative regulation of cell cycle process GO:0010948 37 17 0,000 0,02951172 0,05012979 ! zinc ion transport GO:0006829 22 17 0,000 0,02951172 0,05009393 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02951172 0,05005813 ! protein amino acid deacetylation GO:0006476 23 17 0,000 0,02951172 0,05002237 ! heterophilic cell adhesion GO:0007157 38 17 0,000 0,02951172 0,04998667 ! protein amino acid acetylation GO:0006473 33 17 0,000 0,02951172 0,04995101 ! regulation of neurotransmitter secretion GO:0046928 32 17 0,000 0,02951172 0,04991541 ! forelimb morphogenesis GO:0035136 20 17 0,000 0,02951172 0,04987986 ! negative regulation of ion transport GO:0043271 19 17 0,000 0,02951172 0,04984436 ! regulation of muscle cell differentiation GO:0051147 26 17 0,000 0,02951172 0,04980891 ! adult walking behavior GO:0007628 30 17 0,000 0,02951172 0,0497735 ! patterning of blood vessels GO:0001569 27 17 0,000 0,02951172 0,04973815 ! mechanoreceptor differentiation GO:0042490 32 17 0,000 0,02951172 0,04970285 ! cellular response to hydrogen peroxide GO:0070301 25 17 0,000 0,02951172 0,0496676 GO:0042744|hydrogen peroxide catabolic process, ! retinoid metabolic process GO:0001523 22 17 0,000 0,02951172 0,0496324 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 26 17 0,000 0,02951172 0,04959725 ! positive regulation of proteolysis GO:0045862 21 17 0,000 0,02951172 0,04956215 ! cardiac muscle tissue development GO:0048738 27 17 0,000 0,02951172 0,0495271 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02951172 0,0494921 ! protein polyubiquitination GO:0000209 31 17 0,000 0,02951172 0,04945715 ! cerebral cortex development GO:0021987 34 17 0,000 0,02951172 0,04942224 ! complement activation, alternative pathway GO:0006957 17 17 0,000 0,02951172 0,04938739 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02951172 0,04935259 ! neuromuscular junction development GO:0007528 25 17 0,000 0,02951172 0,04931783 ! L-amino acid transport GO:0015807 27 17 0,000 0,02951172 0,04928313 ! regulation of protein binding GO:0043393 29 17 0,000 0,02951172 0,04924847 ! peptide secretion GO:0002790 30 17 0,000 0,02951172 0,04921386 ! stem cell differentiation GO:0048863 40 17 0,000 0,02951172 0,0491793 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02951172 0,04914479 ! intermediate filament-based process GO:0045103 29 17 0,000 0,02951172 0,04911032 ! protein export from nucleus GO:0006611 26 17 0,000 0,02951172 0,04907591 ! nucleotide-excision repair, DNA gap filling GO:0006297 23 17 0,000 0,02951172 0,04904154 ! diencephalon development GO:0021536 27 17 0,000 0,02951172 0,04900722 ! oogenesis GO:0048477 25 17 0,000 0,02951172 0,04897295 ! long-chain fatty acid transport GO:0015909 25 17 0,000 0,02951172 0,04893873 ! peptide biosynthetic process GO:0043043 22 17 0,000 0,02951172 0,04890455 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02951172 0,04887043 GO:0046467|membrane lipid biosynthetic process, ! biomineral formation GO:0031214 21 17 0,000 0,02951172 0,04883635 ! vitamin A metabolic process GO:0006776 23 17 0,000 0,02951172 0,04880231 ! steroid catabolic process GO:0006706 24 17 0,000 0,02951172 0,04876833 ! porphyrin biosynthetic process GO:0006779 24 17 0,000 0,02951172 0,04873439 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 23 17 0,000 0,02951172 0,0487005 ! nerve development GO:0021675 20 17 0,000 0,02951172 0,04866666 ! negative regulation of homeostatic process GO:0032845 29 17 0,000 0,02951172 0,04863286 ! regulation of mitotic metaphase/anaphase transition GO:0030071 33 17 0,000 0,02951172 0,04859911 ! protein secretion GO:0009306 32 18 0,000 0,0312211 0,05137842 ! regulation of glucose metabolic process GO:0010906 25 18 0,000 0,0312211 0,05134281 ! positive regulation of cell killing GO:0031343 27 18 0,000 0,0312211 0,05130726 ! negative regulation of defense response GO:0031348 21 18 0,000 0,0312211 0,05127175 ! pteridine and derivative metabolic process GO:0042558 23 18 0,000 0,0312211 0,05123629 ! positive regulation of anti-apoptosis GO:0045768 33 18 0,000 0,0312211 0,05120088 ! metencephalon development GO:0022037 25 18 0,000 0,0312211 0,05116552 ! positive regulation of hormone secretion GO:0046887 28 18 0,000 0,0312211 0,05113021 ! hormone secretion GO:0046879 28 18 0,000 0,0312211 0,05109495 ! 2'-deoxyribonucleotide metabolic process GO:0009394 24 18 0,000 0,0312211 0,05105974 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 32 18 0,000 0,0312211 0,05102457 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 27 18 0,000 0,0312211 0,05098946 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,0312211 0,05095439 ! intra-Golgi vesicle-mediated transport GO:0006891 28 18 0,000 0,0312211 0,05091937 ! protein amino acid ADP-ribosylation GO:0006471 30 18 0,000 0,0312211 0,0508844 ! cAMP metabolic process GO:0046058 33 18 0,000 0,0312211 0,05084947 ! transcription from RNA polymerase III promoter GO:0006383 36 18 0,000 0,0312211 0,05081459 ! regulation of postsynaptic membrane potential GO:0060078 31 18 0,000 0,0312211 0,05077977 ! glial cell development GO:0021782 31 18 0,000 0,0312211 0,05074499 ! keratinization GO:0031424 19 18 0,000 0,0312211 0,05071025 ! regulation of systemic arterial blood pressure by hormone GO:0001990 27 18 0,000 0,0312211 0,05067557 GO:0050886|endocrine process, ! myoblast differentiation GO:0045445 31 18 0,000 0,0312211 0,05064093 ! inactivation of MAPK activity GO:0000188 28 18 0,000 0,0312211 0,05060634 ! negative regulation of epithelial cell proliferation GO:0050680 36 18 0,000 0,0312211 0,05057179 ! vacuolar transport GO:0007034 26 18 0,000 0,0312211 0,0505373 ! pigmentation during development GO:0048066 35 18 0,000 0,0312211 0,05050285 ! cell-substrate junction assembly GO:0007044 45 18 0,000 0,0312211 0,05046845 ! cellular macromolecular complex disassembly GO:0034623 30 18 0,000 0,0312211 0,05043409 ! fucose metabolic process GO:0006004 27 18 0,000 0,0312211 0,05039978 ! actin filament bundle formation GO:0051017 30 18 0,000 0,0312211 0,05036552 ! body fluid secretion GO:0007589 27 18 0,000 0,0312211 0,0503313 ! regulation of dephosphorylation GO:0035303 38 18 0,000 0,0312211 0,05029713 ! NLS-bearing substrate import into nucleus GO:0006607 40 18 0,000 0,0312211 0,05026301 ! behavioral interaction between organisms GO:0051705 26 18 0,000 0,0312211 0,05022894 ! negative regulation of immune response GO:0050777 33 18 0,000 0,0312211 0,0501949 ! heart process GO:0003015 32 18 0,000 0,0312211 0,05016092 GO:0060047|heart contraction, ! regulation of T cell mediated immunity GO:0002709 39 18 0,000 0,0312211 0,05012698 ! sensory perception of pain GO:0019233 26 18 0,000 0,0312211 0,05009309 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 18 0,000 0,0312211 0,05005924 ! ribosomal small subunit biogenesis GO:0042274 22 18 0,000 0,0312211 0,05002544 ! somitogenesis GO:0001756 25 18 0,000 0,0312211 0,04999169 ! neural crest cell migration GO:0001755 28 18 0,000 0,0312211 0,04995798 ! neutrophil chemotaxis GO:0030593 26 18 0,000 0,0312211 0,04992431 ! positive regulation of intracellular transport GO:0032388 30 18 0,000 0,0312211 0,04989069 ! negative regulation of intracellular transport GO:0032387 31 18 0,000 0,0312211 0,04985712 ! synaptogenesis GO:0007416 28 18 0,000 0,0312211 0,04982359 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,0312211 0,04979011 ! purine nucleotide catabolic process GO:0006195 27 18 0,000 0,0312211 0,04975667 ! proximal/distal pattern formation GO:0009954 28 18 0,000 0,0312211 0,04972327 ! regulation of generation of precursor metabolites and energy GO:0043467 29 18 0,000 0,0312211 0,04968993 ! aromatic compound catabolic process GO:0019439 26 18 0,000 0,0312211 0,04965662 ! somatic recombination of immunoglobulin gene segments GO:0016447 28 18 0,000 0,0312211 0,04962336 ! gut development GO:0048565 29 18 0,000 0,0312211 0,04959015 ! negative regulation of leukocyte proliferation GO:0070664 35 18 0,000 0,0312211 0,04955698 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! antigen receptor-mediated signaling pathway GO:0050851 33 18 0,000 0,0312211 0,04952385 ! positive regulation of synaptic transmission GO:0050806 26 18 0,000 0,0312211 0,04949077 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 28 19 0,000 0,03292756 0,05216095 ! positive regulation of translation GO:0045727 29 19 0,000 0,03292756 0,05212615 ! phosphatidylinositol metabolic process GO:0046488 24 19 0,000 0,03292756 0,0520914 ! glycerol metabolic process GO:0006071 22 19 0,000 0,03292756 0,05205669 ! phosphoinositide phosphorylation GO:0046854 26 19 0,000 0,03292756 0,05202204 ! regulation of neuronal synaptic plasticity GO:0048168 37 19 0,000 0,03292756 0,05198742 ! endothelial cell migration GO:0043542 24 19 0,000 0,03292756 0,05195286 ! glycosaminoglycan biosynthetic process GO:0006024 27 19 0,000 0,03292756 0,05191834 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 23 19 0,000 0,03292756 0,05188386 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 19 0,000 0,03292756 0,05184943 ! memory GO:0007613 28 19 0,000 0,03292756 0,05181505 ! pancreas development GO:0031016 27 19 0,000 0,03292756 0,05178071 ! response to carbohydrate stimulus GO:0009743 28 19 0,000 0,03292756 0,05174642 ! DNA duplex unwinding GO:0032508 28 19 0,000 0,03292756 0,05171218 GO:0032392|DNA geometric change, ! peroxisome organization GO:0007031 30 19 0,000 0,03292756 0,05167797 ! central nervous system neuron development GO:0021954 33 19 0,000 0,03292756 0,05164382 ! polysaccharide catabolic process GO:0000272 24 19 0,000 0,03292756 0,05160971 ! actin polymerization or depolymerization GO:0008154 32 19 0,000 0,03292756 0,05157564 ! vesicle docking during exocytosis GO:0006904 25 19 0,000 0,03292756 0,05154162 ! heme metabolic process GO:0042168 29 19 0,000 0,03292756 0,05150764 ! negative regulation of protein catabolic process GO:0042177 29 19 0,000 0,03292756 0,05147371 ! response to lipopolysaccharide GO:0032496 28 19 0,000 0,03292756 0,05143983 ! response to fungus GO:0009620 21 19 0,000 0,03292756 0,05140599 ! peptide cross-linking GO:0018149 35 19 0,000 0,03292756 0,05137219 ! ventricular cardiac muscle morphogenesis GO:0055010 25 19 0,000 0,03292756 0,05133843 ! determination of left/right symmetry GO:0007368 24 19 0,000 0,03292756 0,05130473 ! prostaglandin metabolic process GO:0006693 34 19 0,000 0,03292756 0,05127106 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 29 19 0,000 0,03292756 0,05123744 GO:0002712|regulation of B cell mediated immunity, ! detection of chemical stimulus GO:0009593 28 19 0,000 0,03292756 0,05120386 ! vitamin transport GO:0051180 26 19 0,000 0,03292756 0,05117033 ! sarcomere organization GO:0045214 26 19 0,000 0,03292756 0,05113684 ! positive regulation of myeloid cell differentiation GO:0045639 50 19 0,000 0,03292756 0,0511034 ! regulation of immunoglobulin production GO:0002637 29 19 0,000 0,03292756 0,05107 ! positive regulation of transmission of nerve impulse GO:0051971 27 19 0,000 0,03292756 0,05103664 ! leukotriene biosynthetic process GO:0019370 27 19 0,000 0,03292756 0,05100333 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 23 19 0,000 0,03292756 0,05097006 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 25 19 0,000 0,03292756 0,05093683 ! oligosaccharide metabolic process GO:0009311 35 20 0,000 0,03463109 0,05353719 ! positive regulation of angiogenesis GO:0045766 42 20 0,000 0,03463109 0,05350233 ! determination of bilateral symmetry GO:0009855 26 20 0,000 0,03463109 0,05346752 GO:0009799|determination of symmetry, ! N-acetylglucosamine metabolic process GO:0006044 25 20 0,000 0,03463109 0,05343276 ! lipid phosphorylation GO:0046834 28 20 0,000 0,03463109 0,05339804 ! aminoglycan biosynthetic process GO:0006023 28 20 0,000 0,03463109 0,05336337 ! hindlimb morphogenesis GO:0035137 35 20 0,000 0,03463109 0,05332874 ! C21-steroid hormone metabolic process GO:0008207 25 20 0,000 0,03463109 0,05329415 ! calcium-independent cell-cell adhesion GO:0016338 23 20 0,000 0,03463109 0,05325961 ! response to alkaloid GO:0043279 34 20 0,000 0,03463109 0,05322512 ! sensory perception of taste GO:0050909 26 20 0,000 0,03463109 0,05319067 ! response to retinoic acid GO:0032526 27 20 0,000 0,03463109 0,05315626 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 20 0,000 0,03463109 0,0531219 ! cellular response to reactive oxygen species GO:0034614 32 20 0,000 0,03463109 0,05308759 ! D-ribose metabolic process GO:0006014 27 20 0,000 0,03463109 0,05305332 ! cell structure disassembly during apoptosis GO:0006921 25 20 0,000 0,03463109 0,05301909 ! chromosome condensation GO:0030261 32 20 0,000 0,03463109 0,0529849 ! peptidyl-serine phosphorylation GO:0018105 31 20 0,000 0,03463109 0,05295076 ! sex determination GO:0007530 32 20 0,000 0,03463109 0,05291667 ! plasma membrane fusion GO:0045026 24 20 0,000 0,03463109 0,05288262 ! fatty acid beta-oxidation GO:0006635 32 20 0,000 0,03463109 0,05284861 ! positive regulation of alpha-beta T cell differentiation GO:0046638 29 20 0,000 0,03463109 0,05281464 ! cytolysis GO:0019835 21 20 0,000 0,03463109 0,05278072 ! renal system process GO:0003014 35 20 0,000 0,03463109 0,05274685 ! vasodilation GO:0042311 36 20 0,000 0,03463109 0,05271301 ! negative regulation of angiogenesis GO:0016525 38 20 0,000 0,03463109 0,05267922 ! detection of biotic stimulus GO:0009595 23 20 0,000 0,03463109 0,05264547 ! cellular response to nutrient levels GO:0031669 32 20 0,000 0,03463109 0,05261177 ! positive regulation of neurological system process GO:0031646 31 20 0,000 0,03463109 0,05257811 ! hormone transport GO:0009914 30 20 0,000 0,03463109 0,05254449 ! negative regulation of neuron differentiation GO:0045665 33 20 0,000 0,03463109 0,05251092 ! activation of JUN kinase activity GO:0007257 28 20 0,000 0,03463109 0,05247739 ! regulation of leukocyte mediated cytotoxicity GO:0001910 34 20 0,000 0,03463109 0,0524439 ! estrogen receptor signaling pathway GO:0030520 36 20 0,000 0,03463109 0,05241045 ! sperm-egg recognition GO:0035036 24 20 0,000 0,03463109 0,05237705 GO:0007339|binding of sperm to zona pellucida, ! embryonic organ morphogenesis GO:0048562 26 20 0,000 0,03463109 0,05234369 ! negative regulation of translation GO:0017148 28 20 0,000 0,03463109 0,05231037 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 20 0,000 0,03463109 0,05227709 ! positive regulation of DNA replication GO:0045740 37 21 0,000 0,03633171 0,05480938 ! positive regulation of protein catabolic process GO:0045732 25 21 0,000 0,03633171 0,05477456 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03633171 0,05473978 ! positive regulation of ossification GO:0045778 34 21 0,000 0,03633171 0,05470505 ! iron ion transport GO:0006826 49 21 0,000 0,03633171 0,05467036 ! glucosamine metabolic process GO:0006041 26 21 0,000 0,03633171 0,05463571 ! microtubule-based transport GO:0010970 41 21 0,000 0,03633171 0,05460111 ! vesicle docking GO:0048278 28 21 0,000 0,03633171 0,05456655 ! regulation of carbohydrate metabolic process GO:0006109 31 21 0,000 0,03633171 0,05453204 GO:0010675|regulation of cellular carbohydrate metabolic process, ! ovarian follicle development GO:0001541 33 21 0,000 0,03633171 0,05449757 ! response to ethanol GO:0045471 38 21 0,000 0,03633171 0,05446314 ! positive regulation of epithelial cell proliferation GO:0050679 43 21 0,000 0,03633171 0,05442876 ! smooth muscle contraction GO:0006939 39 21 0,000 0,03633171 0,05439442 ! glutamine metabolic process GO:0006541 29 21 0,000 0,03633171 0,05436012 ! response to vitamin A GO:0033189 28 21 0,000 0,03633171 0,05432587 ! purine ribonucleoside metabolic process GO:0046128 30 21 0,000 0,03633171 0,05429166 GO:0042278|purine nucleoside metabolic process, ! neurotransmitter metabolic process GO:0042133 36 21 0,000 0,03633171 0,05425749 ! apoptotic nuclear changes GO:0030262 31 21 0,000 0,03633171 0,05422337 ! response to starvation GO:0042594 35 21 0,000 0,03633171 0,05418929 ! regulation of myeloid leukocyte differentiation GO:0002761 41 21 0,000 0,03633171 0,05415525 ! leukotriene metabolic process GO:0006691 29 21 0,000 0,03633171 0,05412125 ! regulation of vasoconstriction GO:0019229 33 21 0,000 0,03633171 0,0540873 ! glycosphingolipid metabolic process GO:0006687 35 21 0,000 0,03633171 0,05405339 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 28 21 0,000 0,03633171 0,05401952 ! regulation of fatty acid metabolic process GO:0019217 32 21 0,000 0,03633171 0,0539857 ! visual learning GO:0008542 38 21 0,000 0,03633171 0,05395191 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 38 21 0,000 0,03633171 0,05391817 ! positive regulation of inflammatory response GO:0050729 38 21 0,000 0,03633171 0,05388447 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03633171 0,05385082 ! neuromuscular process controlling balance GO:0050885 54 21 0,000 0,03633171 0,0538172 ! negative regulation of myeloid cell differentiation GO:0045638 29 21 0,000 0,03633171 0,05378363 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03633171 0,0537501 ! aromatic amino acid family metabolic process GO:0009072 30 21 0,000 0,03633171 0,05371661 ! somatic diversification of immunoglobulins GO:0016445 31 21 0,000 0,03633171 0,05368316 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,03633171 0,05364975 ! negative regulation of T cell activation GO:0050868 35 21 0,000 0,03633171 0,05361639 ! regulation of microtubule polymerization or depolymerization GO:0031110 51 21 0,000 0,03633171 0,05358307 ! embryonic pattern specification GO:0009880 34 22 0,000 0,03802942 0,05605206 ! regulation of cell killing GO:0031341 37 22 0,000 0,03802942 0,05601727 ! regulation of anti-apoptosis GO:0045767 40 22 0,000 0,03802942 0,05598252 ! gluconeogenesis GO:0006094 26 22 0,000 0,03802942 0,05594781 ! DNA catabolic process, endonucleolytic GO:0000737 27 22 0,000 0,03802942 0,05591315 ! viral genome replication GO:0019079 31 22 0,000 0,03802942 0,05587853 ! nucleotide-excision repair, DNA damage removal GO:0000718 27 22 0,000 0,03802942 0,05584395 ! protein amino acid O-linked glycosylation GO:0006493 36 22 0,000 0,03802942 0,05580941 ! protein amino acid acylation GO:0043543 42 22 0,000 0,03802942 0,05577492 ! response to vitamin GO:0033273 31 22 0,000 0,03802942 0,05574047 ! molting cycle process GO:0022404 43 22 0,000 0,03802942 0,05570606 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of neurotransmitter transport GO:0051588 41 22 0,000 0,03802942 0,0556717 ! regeneration GO:0031099 37 22 0,000 0,03802942 0,05563737 ! phototransduction GO:0007602 29 22 0,000 0,03802942 0,05560309 ! regulation of DNA recombination GO:0000018 43 22 0,000 0,03802942 0,05556885 ! regulation of smooth muscle contraction GO:0006940 38 22 0,000 0,03802942 0,05553466 ! deoxyribonucleotide metabolic process GO:0009262 29 22 0,000 0,03802942 0,0555005 ! central nervous system neuron differentiation GO:0021953 39 22 0,000 0,03802942 0,05546639 ! cholesterol biosynthetic process GO:0006695 32 22 0,000 0,03802942 0,05543232 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 22 0,000 0,03802942 0,05539829 ! regulation of interleukin-6 production GO:0032675 25 22 0,000 0,03802942 0,05536431 ! regulation of interleukin-2 production GO:0032663 38 22 0,000 0,03802942 0,05533036 ! pallium development GO:0021543 43 22 0,000 0,03802942 0,05529646 ! positive regulation of locomotion GO:0040017 40 22 0,000 0,03802942 0,0552626 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! fatty acid transport GO:0015908 33 22 0,000 0,03802942 0,05522878 ! platelet activation GO:0030168 33 22 0,000 0,03802942 0,055195 ! proteoglycan biosynthetic process GO:0030166 33 22 0,000 0,03802942 0,05516126 ! regulation of cytokine secretion GO:0050707 30 22 0,000 0,03802942 0,05512756 ! positive regulation of osteoblast differentiation GO:0045669 37 22 0,000 0,03802942 0,05509391 ! cellular alkene metabolic process GO:0043449 30 22 0,000 0,03802942 0,05506029 ! cell-cell recognition GO:0009988 28 22 0,000 0,03802942 0,05502672 ! pyrimidine nucleoside metabolic process GO:0006213 28 22 0,000 0,03802942 0,05499319 ! water-soluble vitamin biosynthetic process GO:0042364 28 22 0,000 0,03802942 0,0549597 ! neural tube closure GO:0001843 35 22 0,000 0,03802942 0,05492624 GO:0060606|tube closure, ! regulation of multi-organism process GO:0043900 35 22 0,000 0,03802942 0,05489283 ! protein tetramerization GO:0051262 43 22 0,000 0,03802942 0,05485947 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 36 23 0,000 0,03972423 0,0572695 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 31 23 0,000 0,03972423 0,05723472 ! reciprocal meiotic recombination GO:0007131 41 23 0,000 0,03972423 0,05719999 ! cellular aldehyde metabolic process GO:0006081 32 23 0,000 0,03972423 0,05716531 ! positive regulation of bone remodeling GO:0046852 37 23 0,000 0,03972423 0,05713066 ! cellular polysaccharide biosynthetic process GO:0033692 29 23 0,000 0,03972423 0,05709606 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 31 23 0,000 0,03972423 0,05706149 ! dicarboxylic acid metabolic process GO:0043648 36 23 0,000 0,03972423 0,05702697 ! regulation of chemotaxis GO:0050920 41 23 0,000 0,03972423 0,0569925 ! regulation of receptor-mediated endocytosis GO:0048259 26 23 0,000 0,03972423 0,05695806 ! tube lumen formation GO:0035148 37 23 0,000 0,03972423 0,05692367 ! macromolecular complex disassembly GO:0032984 39 23 0,000 0,03972423 0,05688931 ! dendrite development GO:0016358 41 23 0,000 0,03972423 0,056855 ! vasculogenesis GO:0001570 38 23 0,000 0,03972423 0,05682073 ! microtubule organizing center organization GO:0031023 30 23 0,000 0,03972423 0,0567865 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 50 23 0,000 0,03972423 0,05675231 ! lysosome organization GO:0007040 41 23 0,000 0,03972423 0,05671816 ! digestive system process GO:0022600 35 23 0,000 0,03972423 0,05668406 ! positive regulation of cytoskeleton organization GO:0051495 43 23 0,000 0,03972423 0,05664999 ! vesicle targeting GO:0006903 35 23 0,000 0,03972423 0,05661597 ! response to corticosteroid stimulus GO:0031960 37 23 0,000 0,03972423 0,05658199 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 36 23 0,000 0,03972423 0,05654804 ! regulation of endothelial cell migration GO:0010594 44 23 0,000 0,03972423 0,05651414 ! regulation of viral reproduction GO:0050792 33 23 0,000 0,03972423 0,05648028 ! regulation of insulin secretion GO:0050796 30 23 0,000 0,03972423 0,05644646 ! regulation of alpha-beta T cell differentiation GO:0046637 35 23 0,000 0,03972423 0,05641268 ! cardiac muscle tissue morphogenesis GO:0055008 29 23 0,000 0,03972423 0,05637894 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 42 23 0,000 0,03972423 0,05634524 ! membrane depolarization GO:0051899 40 23 0,000 0,03972423 0,05631158 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03972423 0,05627796 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 39 23 0,000 0,03972423 0,05624439 ! regulation of ARF GTPase activity GO:0032312 35 23 0,000 0,03972423 0,05621085 ! DNA modification GO:0006304 33 23 0,000 0,03972423 0,05617735 ! collagen fibril organization GO:0030199 50 23 0,000 0,03972423 0,05614389 ! synaptic vesicle transport GO:0048489 45 23 0,000 0,03972423 0,05611047 ! peptidyl-serine modification GO:0018209 37 23 0,000 0,03972423 0,05607709 ! nerve-nerve synaptic transmission GO:0007270 42 23 0,000 0,03972423 0,05604375 ! fat-soluble vitamin metabolic process GO:0006775 29 23 0,000 0,03972423 0,05601045 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03972423 0,05597719 ! collagen catabolic process GO:0030574 29 23 0,000 0,03972423 0,05594397 ! glutamine family amino acid catabolic process GO:0009065 34 23 0,000 0,03972423 0,05591079 ! aspartate family amino acid metabolic process GO:0009066 27 23 0,000 0,03972423 0,05587765 ! porphyrin metabolic process GO:0006778 37 23 0,000 0,03972423 0,05584454 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 39 23 0,000 0,03972423 0,05581148 ! blastocyst development GO:0001824 41 23 0,000 0,03972423 0,05577846 ! actin filament-based movement GO:0030048 37 23 0,000 0,03972423 0,05574547 ! protein stabilization GO:0050821 34 23 0,000 0,03972423 0,05571252 ! protein import into nucleus, docking GO:0000059 45 24 0,000 0,04141613 0,05805108 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 30 24 0,000 0,04141613 0,05801681 ! myelination GO:0042552 39 24 0,000 0,04141613 0,05798258 ! initiation of viral infection GO:0019059 47 24 0,000 0,04141613 0,05794839 ! regulation of transmembrane transport GO:0034762 31 24 0,000 0,04141613 0,05791425 ! leukocyte adhesion GO:0007159 49 24 0,000 0,04141613 0,05788014 ! glutamate signaling pathway GO:0007215 37 24 0,000 0,04141613 0,05784607 ! regulation of transcription factor import into nucleus GO:0042990 49 24 0,000 0,04141613 0,05781204 ! visual behavior GO:0007632 42 24 0,000 0,04141613 0,05777806 ! spinal cord development GO:0021510 41 24 0,000 0,04141613 0,05774411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 39 24 0,000 0,04141613 0,0577102 ! multicellular organismal response to stress GO:0033555 42 24 0,000 0,04141613 0,05767634 ! regulation of nitric oxide biosynthetic process GO:0045428 42 24 0,000 0,04141613 0,05764251 ! negative regulation of DNA replication GO:0008156 39 24 0,000 0,04141613 0,05760872 ! cell aging GO:0007569 38 24 0,000 0,04141613 0,05757497 ! response to toxin GO:0009636 38 24 0,000 0,04141613 0,05754126 ! primary neural tube formation GO:0014020 37 24 0,000 0,04141613 0,05750759 ! vitamin biosynthetic process GO:0009110 30 24 0,000 0,04141613 0,05747396 ! positive regulation of alpha-beta T cell activation GO:0046635 40 24 0,000 0,04141613 0,05744037 ! cellular response to oxidative stress GO:0034599 38 24 0,000 0,04141613 0,05740682 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 24 0,000 0,04141613 0,05737331 ! fibroblast growth factor receptor signaling pathway GO:0008543 45 24 0,000 0,04141613 0,05733983 ! pentose metabolic process GO:0019321 33 24 0,000 0,04141613 0,0573064 ! immunoglobulin production GO:0002377 37 24 0,000 0,04141613 0,057273 GO:0002440|production of molecular mediator of immune response, ! regulation of response to biotic stimulus GO:0002831 45 24 0,000 0,04141613 0,05723965 ! positive regulation of protein secretion GO:0050714 29 24 0,000 0,04141613 0,05720633 ! positive regulation of adaptive immune response GO:0002821 44 24 0,000 0,04141613 0,05717305 ! regulation of blood coagulation GO:0030193 37 24 0,000 0,04141613 0,05713981 ! positive regulation of tissue remodeling GO:0034105 41 24 0,000 0,04141613 0,05710661 ! group transfer coenzyme metabolic process GO:0006752 29 24 0,000 0,04141613 0,05707345 ! response to molecule of bacterial origin GO:0002237 38 24 0,000 0,04141613 0,05704032 ! positive regulation of JUN kinase activity GO:0043507 33 24 0,000 0,04141613 0,05700724 ! neuron fate commitment GO:0048663 38 25 0,000 0,04310514 0,05929767 ! pyruvate metabolic process GO:0006090 32 25 0,000 0,04310514 0,05926332 ! superoxide metabolic process GO:0006801 33 25 0,000 0,04310514 0,059229 ! detection of light stimulus involved in sensory perception GO:0050962 32 25 0,000 0,04310514 0,05919473 GO:0050908|detection of light stimulus involved in visual perception, ! regulation of cell-matrix adhesion GO:0001952 57 25 0,000 0,04310514 0,05916049 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 44 25 0,000 0,04310514 0,05912629 ! mitochondrial membrane organization GO:0007006 42 25 0,000 0,04310514 0,05909214 ! vacuole organization GO:0007033 43 25 0,000 0,04310514 0,05905802 ! receptor metabolic process GO:0043112 40 25 0,000 0,04310514 0,05902394 ! barbed-end actin filament capping GO:0051016 41 25 0,000 0,04310514 0,0589899 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 35 25 0,000 0,04310514 0,0589559 ! regulation of behavior GO:0050795 45 25 0,000 0,04310514 0,05892194 ! hydrogen peroxide metabolic process GO:0042743 35 25 0,000 0,04310514 0,05888802 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 45 25 0,000 0,04310514 0,05885414 ! lymphocyte proliferation GO:0046651 42 25 0,000 0,04310514 0,05882029 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04310514 0,05878649 ! regulation of tumor necrosis factor production GO:0032680 32 25 0,000 0,04310514 0,05875272 ! leukocyte homeostasis GO:0001776 40 25 0,000 0,04310514 0,05871899 ! positive regulation of nuclear division GO:0051785 41 25 0,000 0,04310514 0,05868531 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 38 25 0,000 0,04310514 0,05865166 ! camera-type eye morphogenesis GO:0048593 43 25 0,000 0,04310514 0,05861805 ! negative regulation of catabolic process GO:0009895 37 25 0,000 0,04310514 0,05858447 ! regulation of amine transport GO:0051952 44 25 0,000 0,04310514 0,05855094 ! liver development GO:0001889 44 25 0,000 0,04310514 0,05851744 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 38 26 0,000 0,04479125 0,06077166 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 31 26 0,000 0,04479125 0,06073694 ! positive regulation of cell projection organization GO:0031346 43 26 0,000 0,04479125 0,06070225 ! regulation of cellular catabolic process GO:0031329 39 26 0,000 0,04479125 0,0606676 ! regulation of interferon-gamma production GO:0032649 33 26 0,000 0,04479125 0,060633 ! cellular iron ion homeostasis GO:0006879 47 26 0,000 0,04479125 0,06059843 ! epidermal growth factor receptor signaling pathway GO:0007173 42 26 0,000 0,04479125 0,0605639 ! amino sugar metabolic process GO:0006040 32 26 0,000 0,04479125 0,06052941 ! protein amino acid alkylation GO:0008213 40 26 0,000 0,04479125 0,06049496 GO:0006479|protein amino acid methylation, ! odontogenesis of dentine-containing tooth GO:0042475 43 26 0,000 0,04479125 0,06046055 ! insulin receptor signaling pathway GO:0008286 48 26 0,000 0,04479125 0,06042617 ! peptidyl-tyrosine phosphorylation GO:0018108 42 26 0,000 0,04479125 0,06039184 ! male gonad development GO:0008584 39 26 0,000 0,04479125 0,06035755 ! neural crest cell development GO:0014032 44 26 0,000 0,04479125 0,06032329 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 35 26 0,000 0,04479125 0,06028908 ! cell fate determination GO:0001709 54 26 0,000 0,04479125 0,0602549 ! regulation of chromosome organization GO:0033044 37 26 0,000 0,04479125 0,06022076 ! regulation of oxidoreductase activity GO:0051341 42 26 0,000 0,04479125 0,06018666 ! detection of visible light GO:0009584 33 26 0,000 0,04479125 0,0601526 ! spermatid development GO:0007286 40 26 0,000 0,04479125 0,06011858 ! regulation of bone mineralization GO:0030500 38 26 0,000 0,04479125 0,06008459 ! regulation of osteoblast differentiation GO:0045667 41 26 0,000 0,04479125 0,06005065 ! acetyl-CoA catabolic process GO:0046356 38 26 0,000 0,04479125 0,06001674 GO:0006099|tricarboxylic acid cycle, ! regulation of JUN kinase activity GO:0043506 39 26 0,000 0,04479125 0,05998287 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04647448 0,06220189 ! spliceosomal snRNP biogenesis GO:0000387 38 27 0,000 0,04647448 0,06216682 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 47 27 0,000 0,04647448 0,0621318 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 42 27 0,000 0,04647448 0,06209682 ! membrane docking GO:0022406 40 27 0,000 0,04647448 0,06206187 ! circadian rhythm GO:0007623 44 27 0,000 0,04647448 0,06202697 ! regulation of endothelial cell proliferation GO:0001936 52 27 0,000 0,04647448 0,0619921 ! positive regulation of innate immune response GO:0045089 34 27 0,000 0,04647448 0,06195727 ! autophagy GO:0006914 36 27 0,000 0,04647448 0,06192248 ! myofibril assembly GO:0030239 40 27 0,000 0,04647448 0,06188774 GO:0055002|striated muscle cell development, ! regulation of cellular ketone metabolic process GO:0010565 38 27 0,000 0,04647448 0,06185303 ! peptide transport GO:0015833 46 27 0,000 0,04647448 0,06181836 ! coenzyme catabolic process GO:0009109 40 27 0,000 0,04647448 0,06178372 ! regulation of peptide secretion GO:0002791 39 27 0,000 0,04647448 0,06174913 ! negative regulation of cell development GO:0010721 67 27 0,000 0,04647448 0,06171458 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 46 27 0,000 0,04647448 0,06168006 ! positive regulation of leukocyte mediated immunity GO:0002705 45 27 0,000 0,04647448 0,06164558 GO:0002708|positive regulation of lymphocyte mediated immunity, ! phospholipid transport GO:0015914 40 27 0,000 0,04647448 0,06161114 ! detection of light stimulus GO:0009583 35 27 0,000 0,04647448 0,06157674 ! glutathione metabolic process GO:0006749 35 27 0,000 0,04647448 0,06154238 ! lipid oxidation GO:0034440 39 27 0,000 0,04647448 0,06150806 GO:0019395|fatty acid oxidation, ! leukocyte proliferation GO:0070661 45 27 0,000 0,04647448 0,06147377 GO:0032943|mononuclear cell proliferation, ! telomere organization GO:0032200 39 27 0,000 0,04647448 0,06143952 GO:0000723|telomere maintenance, ! negative regulation of neuron apoptosis GO:0043524 48 27 0,000 0,04647448 0,06140531 ! protein import into nucleus, translocation GO:0000060 47 28 0,000 0,04815483 0,0635901 ! positive regulation of smooth muscle cell proliferation GO:0048661 45 28 0,000 0,04815483 0,06355473 ! translational initiation GO:0006413 48 28 0,000 0,04815483 0,06351941 ! negative regulation of actin filament depolymerization GO:0030835 44 28 0,000 0,04815483 0,06348412 ! acetyl-CoA metabolic process GO:0006084 42 28 0,000 0,04815483 0,06344887 ! regulation of pH GO:0006885 40 28 0,000 0,04815483 0,06341366 ! negative regulation of protein modification process GO:0031400 56 28 0,000 0,04815483 0,06337849 ! catechol metabolic process GO:0009712 46 28 0,000 0,04815483 0,06334335 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 43 28 0,000 0,04815483 0,06330826 ! cellular carbohydrate biosynthetic process GO:0034637 37 28 0,000 0,04815483 0,06327321 ! iron ion homeostasis GO:0055072 49 28 0,000 0,04815483 0,06323819 ! regulation of biomineral formation GO:0070167 40 28 0,000 0,04815483 0,06320321 ! peptidyl-tyrosine modification GO:0018212 44 28 0,000 0,04815483 0,06316828 ! neurotransmitter secretion GO:0007269 41 28 0,000 0,04815483 0,06313338 ! negative regulation of transcription regulator activity GO:0090048 48 28 0,000 0,04815483 0,06309852 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of lymphocyte activation GO:0051250 48 28 0,000 0,04815483 0,06306369 ! gene silencing GO:0016458 47 28 0,000 0,04815483 0,06302891 ! regulation of coagulation GO:0050818 42 28 0,000 0,04815483 0,06299416 ! negative regulation of actin filament polymerization GO:0030837 45 29 0,000 0,0498323 0,06515265 ! phenol metabolic process GO:0018958 47 29 0,000 0,0498323 0,06511677 ! positive regulation of cell adhesion GO:0045785 54 29 0,000 0,0498323 0,06508093 ! icosanoid biosynthetic process GO:0046456 45 29 0,000 0,0498323 0,06504513 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 39 29 0,000 0,0498323 0,06500937 ! calcium-dependent cell-cell adhesion GO:0016339 36 29 0,000 0,0498323 0,06497365 ! negative regulation of response to external stimulus GO:0032102 39 29 0,000 0,0498323 0,06493797 ! cholesterol transport GO:0030301 48 29 0,000 0,0498323 0,06490233 GO:0015918|sterol transport, ! cholesterol homeostasis GO:0042632 53 29 0,000 0,0498323 0,06486673 GO:0055092|sterol homeostasis, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 39 29 0,000 0,0498323 0,06483117 ! GPI anchor metabolic process GO:0006505 47 29 0,000 0,0498323 0,06479564 ! complement activation, classical pathway GO:0006958 39 29 0,000 0,0498323 0,06476016 ! multicellular organismal catabolic process GO:0044243 36 29 0,000 0,0498323 0,06472471 ! respiratory gaseous exchange GO:0007585 51 29 0,000 0,0498323 0,06468931 ! triglyceride metabolic process GO:0006641 38 29 0,000 0,0498323 0,06465394 ! response to ionizing radiation GO:0010212 55 29 0,000 0,0498323 0,06461861 ! muscle cell development GO:0055001 42 29 0,000 0,0498323 0,06458332 ! response to organic cyclic substance GO:0014070 53 29 0,000 0,0498323 0,06454806 ! regulation of systemic arterial blood pressure GO:0003073 52 29 0,000 0,0498323 0,06451285 ! mesoderm formation GO:0001707 52 29 0,000 0,0498323 0,06447767 ! response to estradiol stimulus GO:0032355 38 29 0,000 0,0498323 0,06444253 ! positive regulation of MAPKKK cascade GO:0043410 45 29 0,000 0,0498323 0,06440744 ! regulation of microtubule cytoskeleton organization GO:0070507 61 29 0,000 0,0498323 0,06437237 ! ensheathment of neurons GO:0007272 48 29 0,000 0,0498323 0,06433735 GO:0008366|axon ensheathment, ! serine family amino acid metabolic process GO:0009069 41 29 0,000 0,0498323 0,06430237 ! spermatid differentiation GO:0048515 45 29 0,000 0,0498323 0,06426742 ! myeloid leukocyte activation GO:0002274 44 29 0,000 0,0498323 0,06423251 ! neural tube formation GO:0001841 46 29 0,000 0,0498323 0,06419764 ! regulation of actin filament depolymerization GO:0030834 47 30 0,000 0,0515069 0,06631898 ! organic anion transport GO:0015711 50 30 0,000 0,0515069 0,06628301 ! cell junction assembly GO:0034329 65 30 0,000 0,0515069 0,06624709 ! acute-phase response GO:0006953 49 30 0,000 0,0515069 0,0662112 ! segmentation GO:0035282 43 30 0,000 0,0515069 0,06617535 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 56 30 0,000 0,0515069 0,06613954 ! negative regulation of protein kinase cascade GO:0010741 58 30 0,000 0,0515069 0,06610377 ! immune response-activating signal transduction GO:0002757 45 30 0,000 0,0515069 0,06606804 ! regulation of protein import into nucleus GO:0042306 56 30 0,000 0,0515069 0,06603235 ! regulation of production of molecular mediator of immune response GO:0002700 47 30 0,000 0,0515069 0,06599669 ! ceramide metabolic process GO:0006672 47 30 0,000 0,0515069 0,06596108 ! formation of primary germ layer GO:0001704 54 30 0,000 0,0515069 0,0659255 ! nicotinamide metabolic process GO:0006769 47 30 0,000 0,0515069 0,06588996 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 50 30 0,000 0,0515069 0,06585446 ! fatty acid catabolic process GO:0009062 45 30 0,000 0,0515069 0,065819 ! regulation of calcium ion transport GO:0051924 40 30 0,000 0,0515069 0,06578357 ! negative regulation of protein polymerization GO:0032272 47 30 0,000 0,0515069 0,06574818 ! negative regulation of protein transport GO:0051224 53 30 0,000 0,0515069 0,06571284 ! response to heat GO:0009408 43 30 0,000 0,0515069 0,06567753 ! establishment of vesicle localization GO:0051650 48 30 0,000 0,0515069 0,06564225 ! alkaloid metabolic process GO:0009820 48 31 0,000 0,05317863 0,06773639 ! response to hydrogen peroxide GO:0042542 48 31 0,000 0,05317863 0,06770005 ! post-embryonic development GO:0009791 50 31 0,000 0,05317863 0,06766375 ! inner ear morphogenesis GO:0042472 43 31 0,000 0,05317863 0,06762749 ! regulation of innate immune response GO:0045088 42 31 0,000 0,05317863 0,06759127 ! ovulation cycle process GO:0022602 46 31 0,000 0,05317863 0,06755508 ! mesoderm morphogenesis GO:0048332 54 31 0,000 0,05317863 0,06751894 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 42 31 0,000 0,05317863 0,06748283 ! immune response-regulating signal transduction GO:0002764 51 31 0,000 0,05317863 0,06744676 ! positive regulation of neurogenesis GO:0050769 49 31 0,000 0,05317863 0,06741074 ! positive regulation of T cell differentiation GO:0045582 45 31 0,000 0,05317863 0,06737474 ! positive regulation of multicellular organism growth GO:0040018 42 31 0,000 0,05317863 0,06733879 ! negative regulation of MAP kinase activity GO:0043407 57 31 0,000 0,05317863 0,06730288 ! sterol biosynthetic process GO:0016126 48 31 0,000 0,05317863 0,067267 ! biogenic amine biosynthetic process GO:0042401 45 31 0,000 0,05317863 0,06723116 ! embryonic epithelial tube formation GO:0001838 50 31 0,000 0,05317863 0,06719537 ! tissue homeostasis GO:0001894 45 31 0,000 0,05317863 0,0671596 GO:0048871|multicellular organismal homeostasis, ! mitotic sister chromatid segregation GO:0000070 47 32 0,000 0,0548475 0,06923039 ! DNA damage checkpoint GO:0000077 57 32 0,000 0,0548475 0,06919358 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 49 32 0,000 0,0548475 0,06915681 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 45 32 0,000 0,0548475 0,06912009 ! negative regulation of protein complex assembly GO:0031333 51 32 0,000 0,0548475 0,0690834 ! regulation of synaptic plasticity GO:0048167 54 32 0,000 0,0548475 0,06904675 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 32 0,000 0,0548475 0,06901014 ! positive regulation of endocytosis GO:0045807 39 32 0,000 0,0548475 0,06897357 ! positive regulation of T cell proliferation GO:0042102 56 32 0,000 0,0548475 0,06893704 ! regulation of striated muscle tissue development GO:0016202 51 32 0,000 0,0548475 0,06890054 ! unsaturated fatty acid biosynthetic process GO:0006636 50 32 0,000 0,0548475 0,06886409 ! regulation of axonogenesis GO:0050770 60 32 0,000 0,0548475 0,06882767 ! telencephalon development GO:0021537 59 32 0,000 0,0548475 0,06879129 ! ovulation cycle GO:0042698 48 32 0,000 0,0548475 0,06875495 ! cofactor catabolic process GO:0051187 52 32 0,000 0,0548475 0,06871865 ! pyridine nucleotide metabolic process GO:0019362 49 32 0,000 0,0548475 0,06868239 ! positive regulation of catabolic process GO:0009896 44 32 0,000 0,0548475 0,06864616 ! placenta development GO:0001890 45 32 0,000 0,0548475 0,06860998 ! symbiosis, encompassing mutualism through parasitism GO:0044403 52 32 0,000 0,0548475 0,06857383 ! vesicle localization GO:0051648 50 32 0,000 0,0548475 0,06853772 ! regulation of muscle development GO:0048634 52 33 0,000 0,05651351 0,07058241 ! mRNA export from nucleus GO:0006406 47 33 0,000 0,05651351 0,07054528 ! negative regulation of secretion GO:0051048 53 33 0,000 0,05651351 0,07050819 ! negative regulation of DNA metabolic process GO:0051053 53 33 0,000 0,05651351 0,07047114 ! glial cell differentiation GO:0010001 65 33 0,000 0,05651351 0,07043412 ! cellular component assembly involved in morphogenesis GO:0010927 52 33 0,000 0,05651351 0,07039715 ! sister chromatid segregation GO:0000819 48 33 0,000 0,05651351 0,07036022 ! sphingoid metabolic process GO:0046519 51 33 0,000 0,05651351 0,07032332 ! maintenance of protein location in cell GO:0032507 66 33 0,000 0,05651351 0,07028646 ! pigment biosynthetic process GO:0046148 55 33 0,000 0,05651351 0,07024964 ! neutral lipid metabolic process GO:0006638 45 33 0,000 0,05651351 0,07021286 GO:0006639|acylglycerol metabolic process, ! erythrocyte differentiation GO:0030218 50 33 0,000 0,05651351 0,07017612 ! nucleotide catabolic process GO:0009166 47 33 0,000 0,05651351 0,07013942 ! nuclear-transcribed mRNA catabolic process GO:0000956 47 33 0,000 0,05651351 0,07010276 ! leukocyte chemotaxis GO:0030595 48 33 0,000 0,05651351 0,07006613 GO:0060326|cell chemotaxis, ! BMP signaling pathway GO:0030509 49 33 0,000 0,05651351 0,07002954 ! calcium-mediated signaling GO:0019722 54 33 0,000 0,05651351 0,06999299 ! cytokine production GO:0001816 49 33 0,000 0,05651351 0,06995648 ! regulation of microtubule-based process GO:0032886 66 33 0,000 0,05651351 0,06992001 ! RNA modification GO:0009451 43 33 0,000 0,05651351 0,06988357 ! positive regulation of immune effector process GO:0002699 53 33 0,000 0,05651351 0,06984717 ! ER to Golgi vesicle-mediated transport GO:0006888 57 34 0,000 0,05817667 0,0718653 ! xenobiotic metabolic process GO:0006805 49 34 0,000 0,05817667 0,07182791 ! actomyosin structure organization GO:0031032 48 34 0,000 0,05817667 0,07179056 ! embryonic skeletal system morphogenesis GO:0048704 49 34 0,000 0,05817667 0,07175325 ! monovalent inorganic cation homeostasis GO:0055067 49 34 0,000 0,05817667 0,07171597 ! negative regulation of DNA binding GO:0043392 54 34 0,000 0,05817667 0,07167874 ! positive regulation of cell development GO:0010720 58 34 0,000 0,05817667 0,07164154 ! response to mechanical stimulus GO:0009612 46 34 0,000 0,05817667 0,07160438 ! cell fate specification GO:0001708 49 34 0,000 0,05817667 0,07156726 ! peripheral nervous system development GO:0007422 58 34 0,000 0,05817667 0,07153018 ! isoprenoid metabolic process GO:0006720 47 34 0,000 0,05817667 0,07149314 ! adult locomotory behavior GO:0008344 54 34 0,000 0,05817667 0,07145613 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 35 0,000 0,05983699 0,07345741 ! phosphoinositide biosynthetic process GO:0046489 54 35 0,000 0,05983699 0,07341942 ! collagen metabolic process GO:0032963 47 35 0,000 0,05983699 0,07338148 ! regulation of ARF protein signal transduction GO:0032012 56 35 0,000 0,05983699 0,07334358 ! metanephros development GO:0001656 61 35 0,000 0,05983699 0,07330571 ! positive regulation of gene-specific transcription GO:0043193 53 35 0,000 0,05983699 0,07326789 ! female gonad development GO:0008585 55 35 0,000 0,05983699 0,0732301 ! lipid homeostasis GO:0055088 63 35 0,000 0,05983699 0,07319235 ! DNA integrity checkpoint GO:0031570 61 35 0,000 0,05983699 0,07315465 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05983699 0,07311698 ! hindbrain development GO:0030902 56 35 0,000 0,05983699 0,07307934 ! Rho protein signal transduction GO:0007266 53 35 0,000 0,05983699 0,07304175 ! positive regulation of lymphocyte differentiation GO:0045621 51 35 0,000 0,05983699 0,0730042 ! hormone biosynthetic process GO:0042446 49 35 0,000 0,05983699 0,07296668 ! cytokinesis GO:0000910 57 35 0,000 0,05983699 0,07292921 ! embryonic organ development GO:0048568 53 35 0,000 0,05983699 0,07289177 ! pyrimidine nucleotide metabolic process GO:0006220 48 35 0,000 0,05983699 0,07285437 ! negative regulation of cell activation GO:0050866 58 35 0,000 0,05983699 0,07281701 ! protein homooligomerization GO:0051260 59 35 0,000 0,05983699 0,07277969 ! meiosis I GO:0007127 61 36 0,000 0,06149445 0,07475734 ! negative regulation of cell adhesion GO:0007162 78 36 0,000 0,06149445 0,07471907 ! regulation of metal ion transport GO:0010959 50 36 0,000 0,06149445 0,07468083 ! regulation of intracellular protein transport GO:0033157 64 36 0,000 0,06149445 0,07464263 ! development of primary male sexual characteristics GO:0046546 52 36 0,000 0,06149445 0,07460447 ! spliceosome assembly GO:0000245 65 36 0,000 0,06149445 0,07456634 ! mismatch repair GO:0006298 42 36 0,000 0,06149445 0,07452826 ! regulation of action potential in neuron GO:0019228 60 36 0,000 0,06149445 0,07449022 ! glycerol ether metabolic process GO:0006662 49 36 0,000 0,06149445 0,07445221 ! regulation of proteolysis GO:0030162 53 36 0,000 0,06149445 0,07441425 ! energy coupled proton transport, down electrochemical gradient GO:0015985 55 36 0,000 0,06149445 0,07437632 GO:0015986|ATP synthesis coupled proton transport, ! dorsal/ventral pattern formation GO:0009953 50 36 0,000 0,06149445 0,07433843 ! cellular response to insulin stimulus GO:0032869 60 36 0,000 0,06149445 0,07430058 ! regulation of smooth muscle cell proliferation GO:0048660 60 37 0,000 0,06314908 0,07626095 ! positive regulation of DNA metabolic process GO:0051054 64 37 0,000 0,06314908 0,07622216 ! mammary gland development GO:0030879 73 37 0,000 0,06314908 0,07618341 ! positive regulation of JAK-STAT cascade GO:0046427 49 37 0,000 0,06314908 0,0761447 ! ear morphogenesis GO:0042471 50 37 0,000 0,06314908 0,07610603 ! odontogenesis GO:0042476 60 37 0,000 0,06314908 0,0760674 ! negative regulation of binding GO:0051100 59 37 0,000 0,06314908 0,0760288 ! mitotic cell cycle checkpoint GO:0007093 74 37 0,000 0,06314908 0,07599025 ! tissue remodeling GO:0048771 65 37 0,000 0,06314908 0,07595173 ! carbohydrate homeostasis GO:0033500 45 37 0,000 0,06314908 0,07591326 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 58 37 0,000 0,06314908 0,07587482 ! natural killer cell activation GO:0030101 45 37 0,000 0,06314908 0,07583642 ! androgen receptor signaling pathway GO:0030521 66 37 0,000 0,06314908 0,07579806 ! positive regulation of transcription factor activity GO:0051091 57 38 0,000 0,06480088 0,0777414 GO:0090047|positive regulation of transcription regulator activity, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 48 38 0,000 0,06480088 0,07770211 GO:0006956|complement activation, ! regulation of hormone secretion GO:0046883 54 38 0,000 0,06480088 0,07766287 ! regulation of neuron projection development GO:0010975 73 38 0,000 0,06480088 0,07762367 ! feeding behavior GO:0007631 50 38 0,000 0,06480088 0,0775845 ! organic ether metabolic process GO:0018904 51 38 0,000 0,06480088 0,07754538 ! antigen processing and presentation of peptide antigen GO:0048002 67 38 0,000 0,06480088 0,07750629 ! development of primary female sexual characteristics GO:0046545 59 38 0,000 0,06480088 0,07746724 GO:0046660|female sex differentiation, ! regulation of Rab protein signal transduction GO:0032483 58 38 0,000 0,06480088 0,07742824 GO:0032313|regulation of Rab GTPase activity, ! multicellular organismal macromolecule metabolic process GO:0044259 51 38 0,000 0,06480088 0,07738927 ! ion transmembrane transport GO:0034220 58 38 0,000 0,06480088 0,07735034 ! heterocycle biosynthetic process GO:0018130 49 38 0,000 0,06480088 0,07731145 ! ribonucleoside metabolic process GO:0009119 51 38 0,000 0,06480088 0,0772726 ! neuron migration GO:0001764 59 38 0,000 0,06480088 0,07723379 ! maintenance of protein location GO:0045185 72 38 0,000 0,06480088 0,07719502 ! pigment metabolic process GO:0042440 66 38 0,000 0,06480088 0,07715629 ! regulation of cell morphogenesis involved in differentiation GO:0010769 72 38 0,000 0,06480088 0,07711759 ! mRNA catabolic process GO:0006402 58 39 0,000 0,06644984 0,07904034 ! response to reactive oxygen species GO:0000302 64 39 0,000 0,06644984 0,07900074 ! striated muscle cell differentiation GO:0051146 58 39 0,000 0,06644984 0,07896118 ! neural tube development GO:0021915 58 39 0,000 0,06644984 0,07892166 ! polysaccharide biosynthetic process GO:0000271 51 39 0,000 0,06644984 0,07888218 ! regulation of protein stability GO:0031647 58 39 0,000 0,06644984 0,07884274 ! female gamete generation GO:0007292 50 39 0,000 0,06644984 0,07880334 ! aerobic respiration GO:0009060 56 39 0,000 0,06644984 0,07876397 ! response to xenobiotic stimulus GO:0009410 55 39 0,000 0,06644984 0,07872465 ! protein amino acid N-linked glycosylation GO:0006487 57 40 0,000 0,06809598 0,08063462 ! Notch signaling pathway GO:0007219 64 40 0,000 0,06809598 0,0805944 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 68 40 0,000 0,06809598 0,08055422 ! monocarboxylic acid transport GO:0015718 68 40 0,000 0,06809598 0,08051409 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 71 40 0,000 0,06809598 0,08047399 ! hormone-mediated signaling GO:0009755 57 40 0,000 0,06809598 0,08043393 ! phagocytosis GO:0006909 65 40 0,000 0,06809598 0,08039392 ! mesenchymal cell development GO:0014031 70 40 0,000 0,06809598 0,08035394 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! erythrocyte homeostasis GO:0034101 60 40 0,000 0,06809598 0,080314 ! B cell differentiation GO:0030183 70 40 0,000 0,06809598 0,0802741 ! pigmentation GO:0043473 81 40 0,000 0,06809598 0,08023425 ! developmental growth GO:0048589 70 40 0,000 0,06809598 0,08019443 ! synapse organization GO:0050808 61 40 0,000 0,06809598 0,08015465 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 61 41 0,000 0,06973931 0,08204828 ! RNA export from nucleus GO:0006405 57 41 0,000 0,06973931 0,08200762 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 72 41 0,000 0,06973931 0,081967 ! detection of stimulus involved in sensory perception GO:0050906 55 41 0,000 0,06973931 0,08192642 ! regulation of epithelial cell proliferation GO:0050678 80 41 0,000 0,06973931 0,08188588 ! ATP synthesis coupled electron transport GO:0042773 50 41 0,000 0,06973931 0,08184539 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein secretion GO:0050708 55 41 0,000 0,06973931 0,08180493 ! cell growth GO:0016049 71 41 0,000 0,06973931 0,08176451 ! maintenance of location in cell GO:0051651 77 41 0,000 0,06973931 0,08172413 ! transforming growth factor beta receptor signaling pathway GO:0007179 59 42 0,000 0,07137981 0,08360528 ! regulation of nucleocytoplasmic transport GO:0046822 75 42 0,000 0,07137981 0,08356403 ! learning GO:0007612 75 42 0,000 0,07137981 0,08352283 ! negative regulation of protein complex disassembly GO:0043242 78 42 0,000 0,07137981 0,08348166 ! cellular amide metabolic process GO:0043603 63 42 0,000 0,07137981 0,08344054 ! morphogenesis of embryonic epithelium GO:0016331 69 42 0,000 0,07137981 0,08339945 ! gliogenesis GO:0042063 85 42 0,000 0,07137981 0,08335841 ! endosome transport GO:0016197 74 42 0,000 0,07137981 0,08331741 ! male sex differentiation GO:0046661 62 42 0,000 0,07137981 0,08327645 ! double-strand break repair GO:0006302 75 42 0,000 0,07137981 0,08323552 ! regulation of myeloid cell differentiation GO:0045637 78 42 0,000 0,07137981 0,08319464 ! oxidoreduction coenzyme metabolic process GO:0006733 62 42 0,000 0,07137981 0,0831538 ! mitochondrial transport GO:0006839 66 43 0,000 0,07301751 0,08501989 ! protein amino acid lipidation GO:0006497 69 43 0,000 0,07301751 0,0849782 ! regulation of tube size GO:0035150 69 43 0,000 0,07301751 0,08493654 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 78 43 0,000 0,07301751 0,08489493 ! regulation of T cell proliferation GO:0042129 72 43 0,000 0,07301751 0,08485335 ! positive regulation of DNA binding GO:0043388 65 43 0,000 0,07301751 0,08481182 ! T cell differentiation GO:0030217 78 43 0,000 0,07301751 0,08477032 ! icosanoid metabolic process GO:0006690 65 43 0,000 0,07301751 0,08472887 ! amino acid activation GO:0043038 61 43 0,000 0,07301751 0,08468746 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of protein transport GO:0051222 59 43 0,000 0,07301751 0,08464609 ! epithelial cell differentiation GO:0030855 64 44 0,000 0,0746524 0,08649909 ! receptor-mediated endocytosis GO:0006898 85 44 0,000 0,0746524 0,08645687 ! cellular component disassembly GO:0022411 66 44 0,000 0,0746524 0,0864147 ! cytoskeleton-dependent intracellular transport GO:0030705 78 44 0,000 0,0746524 0,08637257 ! peptide metabolic process GO:0006518 64 44 0,000 0,0746524 0,08633048 ! multicellular organismal metabolic process GO:0044236 57 44 0,000 0,0746524 0,08628843 ! inner ear development GO:0048839 66 44 0,000 0,0746524 0,08624642 ! regulation of lymphocyte mediated immunity GO:0002706 77 44 0,000 0,0746524 0,08620445 ! regulation of gene expression, epigenetic GO:0040029 86 44 0,000 0,0746524 0,08616252 ! chromatin remodeling GO:0006338 73 44 0,000 0,0746524 0,08612063 ! biopolymer methylation GO:0043414 67 44 0,000 0,0746524 0,08607878 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 58 44 0,000 0,0746524 0,08603698 ! JNK cascade GO:0007254 66 44 0,000 0,0746524 0,08599521 ! JAK-STAT cascade GO:0007259 62 44 0,000 0,0746524 0,08595349 ! regulation of cell shape GO:0008360 83 44 0,000 0,0746524 0,0859118 ! activation of adenylate cyclase activity GO:0007190 79 45 0,000 0,07628449 0,0877475 ! positive regulation of binding GO:0051099 67 45 0,000 0,07628449 0,08770498 ! stress-activated protein kinase signaling pathway GO:0031098 69 45 0,000 0,07628449 0,08766251 ! regulation of ion transport GO:0043269 60 45 0,000 0,07628449 0,08762008 ! glucose transport GO:0015758 60 45 0,000 0,07628449 0,08757769 ! neuromuscular process GO:0050905 89 45 0,000 0,07628449 0,08753534 ! positive regulation of cytokine biosynthetic process GO:0042108 61 45 0,000 0,07628449 0,08749303 ! glycosaminoglycan metabolic process GO:0030203 68 45 0,000 0,07628449 0,08745076 ! regulation of T cell differentiation GO:0045580 68 45 0,000 0,07628449 0,08740854 ! response to insulin stimulus GO:0032868 71 45 0,000 0,07628449 0,08736635 ! regulation of actin filament polymerization GO:0030833 71 46 0,000 0,07791378 0,08918929 ! regulation of translational initiation GO:0006446 70 46 0,000 0,07791378 0,08914628 ! regulation of JAK-STAT cascade GO:0046425 68 46 0,000 0,07791378 0,08910332 ! regulation of action potential GO:0001508 80 46 0,000 0,07791378 0,0890604 ! hexose transport GO:0008645 62 46 0,000 0,07791378 0,08901752 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 70 46 0,000 0,07791378 0,08897468 ! excretion GO:0007588 72 46 0,000 0,07791378 0,08893189 ! regulation of leukocyte mediated immunity GO:0002703 80 46 0,000 0,07791378 0,08888913 ! regulation of inflammatory response GO:0050727 74 46 0,000 0,07791378 0,08884642 ! epithelial tube morphogenesis GO:0060562 73 46 0,000 0,07791378 0,08880374 ! positive regulation of defense response GO:0031349 70 47 0,000 0,07954028 0,09061406 ! branching morphogenesis of a tube GO:0048754 85 47 0,000 0,07954028 0,09057057 ! embryonic skeletal system development GO:0048706 65 47 0,000 0,07954028 0,09052714 ! unsaturated fatty acid metabolic process GO:0033559 71 47 0,000 0,07954028 0,09048374 ! lipoprotein biosynthetic process GO:0042158 74 47 0,000 0,07954028 0,09044038 ! regulation of JNK cascade GO:0046328 72 47 0,000 0,07954028 0,09039707 ! positive regulation of adenylate cyclase activity GO:0045762 90 48 0,000 0,08116399 0,09219825 ! viral infectious cycle GO:0019058 80 48 0,000 0,08116399 0,09215414 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 75 48 0,000 0,08116399 0,09211007 ! leukocyte migration GO:0050900 76 48 0,000 0,08116399 0,09206604 ! cellular amino acid biosynthetic process GO:0008652 60 48 0,000 0,08116399 0,09202205 ! striated muscle contraction GO:0006941 78 48 0,000 0,08116399 0,0919781 ! vascular process in circulatory system GO:0003018 78 48 0,000 0,08116399 0,0919342 ! DNA-dependent DNA replication GO:0006261 73 48 0,000 0,08116399 0,09189034 ! tRNA processing GO:0008033 56 48 0,000 0,08116399 0,09184652 ! cell maturation GO:0048469 69 48 0,000 0,08116399 0,09180274 ! detection of abiotic stimulus GO:0009582 66 48 0,000 0,08116399 0,091759 ! regulation of neuron apoptosis GO:0043523 84 48 0,000 0,08116399 0,09171531 ! respiratory electron transport chain GO:0022904 63 49 0,000 0,08278492 0,09350244 ! regulation of cell projection organization GO:0031344 95 49 0,000 0,08278492 0,09345795 ! glycolysis GO:0006096 63 49 0,000 0,08278492 0,09341351 ! regulation of gene-specific transcription GO:0032583 78 49 0,000 0,08278492 0,09336911 ! regulation of protein complex disassembly GO:0043244 88 49 0,000 0,08278492 0,09332476 ! induction of apoptosis by extracellular signals GO:0008624 96 49 0,000 0,08278492 0,09328045 ! response to temperature stimulus GO:0009266 66 49 0,000 0,08278492 0,09323617 ! endocrine system development GO:0035270 86 49 0,000 0,08278492 0,09319194 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08278492 0,09314776 ! generation of a signal involved in cell-cell signaling GO:0003001 74 49 0,000 0,08278492 0,09310361 ! gastrulation GO:0007369 80 49 0,000 0,08278492 0,09305951 ! RNA elongation from RNA polymerase II promoter GO:0006368 65 49 0,000 0,08278492 0,09301544 ! positive regulation of cyclase activity GO:0031281 91 49 0,000 0,08278492 0,09297142 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 84 49 0,000 0,08278492 0,09292744 ! regulation of intracellular transport GO:0032386 83 49 0,000 0,08278492 0,09288351 ! methylation GO:0032259 74 49 0,000 0,08278492 0,09283961 ! cell redox homeostasis GO:0045454 72 50 0,000 0,08440307 0,09460959 ! negative regulation of cell migration GO:0030336 105 50 0,000 0,08440307 0,09456492 ! regulation of muscle contraction GO:0006937 75 50 0,000 0,08440307 0,09452029 ! histone modification GO:0016570 81 50 0,000 0,08440307 0,0944757 ! positive regulation of lyase activity GO:0051349 92 50 0,000 0,08440307 0,09443116 ! heterocycle catabolic process GO:0046700 74 50 0,000 0,08440307 0,09438666 ! RNA catabolic process GO:0006401 77 51 0,000 0,08601845 0,0961478 ! chloride transport GO:0006821 78 51 0,000 0,08601845 0,09610254 ! positive regulation of caspase activity GO:0043280 77 51 0,000 0,08601845 0,09605731 GO:0010952|positive regulation of peptidase activity, ! membrane fusion GO:0006944 82 51 0,000 0,08601845 0,09601213 ! regulation of ossification GO:0030278 82 51 0,000 0,08601845 0,09596699 ! heart morphogenesis GO:0003007 71 51 0,000 0,08601845 0,09592189 ! RNA elongation GO:0006354 67 51 0,000 0,08601845 0,09587684 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 74 51 0,000 0,08601845 0,09583183 ! aminoglycan metabolic process GO:0006022 77 52 0,000 0,08763106 0,0975826 ! activation of phospholipase C activity GO:0007202 93 52 0,000 0,08763106 0,09753683 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 79 52 0,000 0,08763106 0,0974911 ! regulation of DNA replication GO:0006275 88 52 0,000 0,08763106 0,09744541 ! immunoglobulin mediated immune response GO:0016064 72 52 0,000 0,08763106 0,09739977 GO:0019724|B cell mediated immunity, ! cell recognition GO:0008037 78 52 0,000 0,08763106 0,09735417 ! covalent chromatin modification GO:0016569 90 52 0,000 0,08763106 0,09730862 ! regulation of adaptive immune response GO:0002819 90 52 0,000 0,08763106 0,0972631 ! proton transport GO:0015992 78 52 0,000 0,08763106 0,09721763 ! negative regulation of immune system process GO:0002683 90 52 0,000 0,08763106 0,0971722 ! protein amino acid autophosphorylation GO:0046777 97 52 0,000 0,08763106 0,09712682 ! transition metal ion transport GO:0000041 88 53 0,000 0,08924091 0,09886493 ! regulation of angiogenesis GO:0045765 105 53 0,000 0,08924091 0,0988188 ! muscle fiber development GO:0048747 80 53 0,000 0,08924091 0,0987727 ! sulfur compound biosynthetic process GO:0044272 71 53 0,000 0,08924091 0,09872666 ! positive regulation of phospholipase activity GO:0010518 94 53 0,000 0,08924091 0,09868065 ! cytokine-mediated signaling pathway GO:0019221 77 53 0,000 0,08924091 0,09863469 ! regulation of multicellular organism growth GO:0040014 72 53 0,000 0,08924091 0,09858877 ! regulation of endocytosis GO:0030100 71 53 0,000 0,08924091 0,09854289 ! regulation of lymphocyte differentiation GO:0045619 84 53 0,000 0,08924091 0,09849706 ! glutamine family amino acid metabolic process GO:0009064 71 53 0,000 0,08924091 0,09845127 ! cellular amino acid derivative biosynthetic process GO:0042398 73 53 0,000 0,08924091 0,09840552 ! maintenance of location GO:0051235 94 53 0,000 0,08924091 0,09835981 ! hydrogen transport GO:0006818 81 54 0,000 0,090848 0,10008463 ! response to estrogen stimulus GO:0043627 88 54 0,000 0,090848 0,10003819 ! regulation of mitosis GO:0007088 91 54 0,000 0,090848 0,09999179 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 100 54 0,000 0,090848 0,09994543 ! negative regulation of cytoskeleton organization GO:0051494 96 54 0,000 0,090848 0,09989912 ! regulation of actin polymerization or depolymerization GO:0008064 81 54 0,000 0,090848 0,09985285 ! nucleotide-excision repair GO:0006289 70 54 0,000 0,090848 0,09980662 ! sphingolipid metabolic process GO:0006665 80 54 0,000 0,090848 0,09976043 ! ribonucleoprotein complex assembly GO:0022618 90 54 0,000 0,090848 0,09971429 ! morphogenesis of a branching structure GO:0001763 99 54 0,000 0,090848 0,09966819 ! germ cell development GO:0007281 82 54 0,000 0,090848 0,09962213 ! positive regulation of cytokine production GO:0001819 83 54 0,000 0,090848 0,09957612 ! regulation of protein polymerization GO:0032271 84 54 0,000 0,090848 0,09953015 ! establishment of organelle localization GO:0051656 91 54 0,000 0,090848 0,09948422 ! glycerophospholipid biosynthetic process GO:0046474 82 55 0,000 0,09245233 0,10119436 ! ear development GO:0043583 83 55 0,000 0,09245233 0,10114771 ! regulation of phospholipase activity GO:0010517 96 55 0,000 0,09245233 0,10110109 ! regulation of protein catabolic process GO:0042176 83 55 0,000 0,09245233 0,10105453 ! integrin-mediated signaling pathway GO:0007229 93 55 0,000 0,09245233 0,101008 ! positive regulation of lipase activity GO:0060193 96 55 0,000 0,09245233 0,10096152 ! regulation of actin filament length GO:0030832 88 56 0,000 0,09405391 0,10266326 ! positive regulation of secretion GO:0051047 83 56 0,000 0,09405391 0,10261606 ! nucleoside metabolic process GO:0009116 74 56 0,000 0,09405391 0,1025689 ! DNA catabolic process GO:0006308 71 56 0,000 0,09405391 0,10252179 ! positive regulation of organelle organization GO:0010638 95 56 0,000 0,09405391 0,10247471 ! adult behavior GO:0030534 90 56 0,000 0,09405391 0,10242769 ! cartilage development GO:0051216 84 56 0,000 0,09405391 0,1023807 ! regulation of neurotransmitter levels GO:0001505 85 57 0,000 0,09565275 0,10407335 ! mesoderm development GO:0007498 84 57 0,000 0,09565275 0,10402565 ! aging GO:0007568 91 57 0,000 0,09565275 0,103978 ! nuclear export GO:0051168 85 57 0,000 0,09565275 0,10393039 ! cellular amino acid catabolic process GO:0009063 82 57 0,000 0,09565275 0,10388282 ! single fertilization GO:0007338 67 57 0,000 0,09565275 0,1038353 ! regulation of cellular component size GO:0032535 90 58 0,000 0,09724884 0,10551966 ! lipid modification GO:0030258 82 58 0,000 0,09724884 0,10547143 ! membrane lipid metabolic process GO:0006643 88 58 0,000 0,09724884 0,10542325 ! negative regulation of cell motion GO:0051271 118 58 0,000 0,09724884 0,10537511 ! regulation of bone remodeling GO:0046850 102 59 0,000 0,0988422 0,10705273 ! viral reproductive process GO:0022415 99 59 0,000 0,0988422 0,10700389 ! skeletal system morphogenesis GO:0048705 90 59 0,000 0,0988422 0,1069551 ! chromosome segregation GO:0007059 93 59 0,000 0,0988422 0,10690635 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0988422 0,10685765 ! negative regulation of response to stimulus GO:0048585 88 59 0,000 0,0988422 0,10680899 ! cell projection assembly GO:0030031 90 59 0,000 0,0988422 0,10676037 ! glucose catabolic process GO:0006007 78 60 0,000 0,10043282 0,10842907 ! regulation of lipid metabolic process GO:0019216 93 60 0,000 0,10043282 0,10837976 ! water-soluble vitamin metabolic process GO:0006767 84 60 0,000 0,10043282 0,1083305 ! response to peptide hormone stimulus GO:0043434 97 60 0,000 0,10043282 0,10828128 ! kidney development GO:0001822 101 60 0,000 0,10043282 0,1082321 ! positive regulation of cell motion GO:0051272 110 60 0,000 0,10043282 0,10818297 ! regulation of protein complex assembly GO:0043254 95 61 0,000 0,10202072 0,10984355 ! carbohydrate transport GO:0008643 83 61 0,000 0,10202072 0,10979373 ! protein maturation by peptide bond cleavage GO:0051605 86 61 0,000 0,10202072 0,10974396 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 98 62 0,000 0,1036059 0,11139864 ! amino acid transport GO:0006865 97 62 0,000 0,1036059 0,11134819 ! activation of MAPK activity GO:0000187 95 62 0,000 0,1036059 0,11129778 ! multicellular organism reproduction GO:0032504 98 62 0,000 0,1036059 0,11124742 GO:0048609|reproductive process in a multicellular organism, ! lipoprotein metabolic process GO:0042157 96 62 0,000 0,1036059 0,1111971 ! glycerolipid biosynthetic process GO:0045017 92 62 0,000 0,1036059 0,11114683 ! detection of external stimulus GO:0009581 78 62 0,000 0,1036059 0,11109661 ! regulation of tissue remodeling GO:0034103 113 62 0,000 0,1036059 0,11104643 ! secondary metabolic process GO:0019748 95 62 0,000 0,1036059 0,1109963 ! gonad development GO:0008406 91 62 0,000 0,1036059 0,11094621 ! exocytosis GO:0006887 91 63 0,000 0,10518836 0,11258997 ! oxygen and reactive oxygen species metabolic process GO:0006800 89 63 0,000 0,10518836 0,11253921 ! embryonic limb morphogenesis GO:0030326 96 63 0,000 0,10518836 0,11248849 GO:0035113|embryonic appendage morphogenesis, ! coenzyme biosynthetic process GO:0009108 81 63 0,000 0,10518836 0,11243782 ! regulation of heart contraction GO:0008016 104 63 0,000 0,10518836 0,1123872 ! developmental maturation GO:0021700 90 63 0,000 0,10518836 0,11233662 ! fertilization GO:0009566 79 64 0,000 0,1067681 0,11397242 ! viral reproduction GO:0016032 104 64 0,000 0,1067681 0,11392118 ! myeloid cell differentiation GO:0030099 101 64 0,000 0,1067681 0,11386998 ! amine catabolic process GO:0009310 100 65 0,000 0,10834513 0,1155 ! camera-type eye development GO:0043010 103 65 0,000 0,10834513 0,11544814 ! steroid hormone receptor signaling pathway GO:0030518 116 65 0,000 0,10834513 0,11539632 ! regulation of lipase activity GO:0060191 117 65 0,000 0,10834513 0,11534455 ! regulation of homeostatic process GO:0032844 122 65 0,000 0,10834513 0,11529282 ! organelle localization GO:0051640 105 65 0,000 0,10834513 0,11524115 ! regulation of transcription factor activity GO:0051090 109 66 0,000 0,10991946 0,1168633 GO:0090046|regulation of transcription regulator activity, ! cellular hormone metabolic process GO:0034754 95 66 0,000 0,10991946 0,11681096 ! sensory perception of smell GO:0007608 81 66 0,000 0,10991946 0,11675868 ! regulation of cytokine biosynthetic process GO:0042035 91 66 0,000 0,10991946 0,11670643 ! cAMP-mediated signaling GO:0019933 109 66 0,000 0,10991946 0,11665424 ! lung development GO:0030324 112 66 0,000 0,10991946 0,11660209 ! B cell activation GO:0042113 119 66 0,000 0,10991946 0,11654999 ! protein oligomerization GO:0051259 109 66 0,000 0,10991946 0,11649794 ! cell cycle checkpoint GO:0000075 123 67 0,000 0,11149109 0,11811087 ! neurotransmitter transport GO:0006836 92 67 0,000 0,11149109 0,11805817 ! regulation of cellular response to stress GO:0080135 100 67 0,000 0,11149109 0,11800551 ! appendage morphogenesis GO:0035107 103 67 0,000 0,11149109 0,1179529 GO:0035108|limb morphogenesis, ! fatty acid biosynthetic process GO:0006633 107 67 0,000 0,11149109 0,11790034 ! extracellular matrix organization GO:0030198 117 67 0,000 0,11149109 0,11784782 ! meiosis GO:0007126 110 68 0,000 0,11306002 0,119453 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide metabolic process GO:0030384 100 68 0,000 0,11306002 0,11939984 ! defense response to bacterium GO:0042742 79 68 0,000 0,11306002 0,11934672 ! regulation of vesicle-mediated transport GO:0060627 98 68 0,000 0,11306002 0,11929366 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 109 68 0,000 0,11306002 0,11924064 ! activation of immune response GO:0002253 93 68 0,000 0,11306002 0,11918766 ! appendage development GO:0048736 108 69 0,000 0,11462626 0,12078513 GO:0060173|limb development, ! respiratory tube development GO:0030323 117 69 0,000 0,11462626 0,12073152 ! urogenital system development GO:0001655 114 69 0,000 0,11462626 0,12067796 ! meiotic cell cycle GO:0051321 111 69 0,000 0,11462626 0,12062444 ! hexose catabolic process GO:0019320 95 70 0,000 0,11618982 0,12221562 ! adaptive immune response GO:0002250 102 70 0,000 0,11618982 0,12216147 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 104 71 0,000 0,11775069 0,12374774 ! cell-matrix adhesion GO:0007160 133 71 0,000 0,11775069 0,12369296 ! elevation of cytosolic calcium ion concentration GO:0007204 126 71 0,000 0,11775069 0,12363822 ! axon guidance GO:0007411 116 71 0,000 0,11775069 0,12358354 ! intracellular receptor-mediated signaling pathway GO:0030522 124 71 0,000 0,11775069 0,12352891 ! regulation of actin cytoskeleton organization GO:0032956 120 72 0,000 0,11930888 0,12510825 ! response to drug GO:0042493 115 72 0,000 0,11930888 0,12505299 ! cytosolic calcium ion homeostasis GO:0051480 128 72 0,000 0,11930888 0,12499778 ! homeostasis of number of cells GO:0048872 109 72 0,000 0,11930888 0,12494262 ! positive regulation of T cell activation GO:0050870 117 72 0,000 0,11930888 0,12488751 ! respiratory system development GO:0060541 123 72 0,000 0,11930888 0,12483244 ! rhythmic process GO:0048511 113 72 0,000 0,11930888 0,12477743 ! regulation of immune effector process GO:0002697 121 72 0,000 0,11930888 0,12472246 ! learning or memory GO:0007611 132 73 0,000 0,1208644 0,12629292 ! humoral immune response GO:0006959 93 73 0,000 0,1208644 0,12623734 ! regulation of MAPKKK cascade GO:0043408 123 73 0,000 0,1208644 0,1261818 ! acute inflammatory response GO:0002526 107 74 0,000 0,12241725 0,12774677 ! activation of protein kinase activity GO:0032147 115 74 0,000 0,12241725 0,12769061 ! regulation of actin filament-based process GO:0032970 122 74 0,000 0,12241725 0,12763451 ! development of primary sexual characteristics GO:0045137 107 74 0,000 0,12241725 0,12757846 ! transcription initiation from RNA polymerase II promoter GO:0006367 100 74 0,000 0,12241725 0,12752245 ! regulation of neuron differentiation GO:0045664 130 74 0,000 0,12241725 0,1274665 ! regulation of Rho protein signal transduction GO:0035023 126 74 0,000 0,12241725 0,12741059 ! regulation of synaptic transmission GO:0050804 117 74 0,000 0,12241725 0,12735473 ! inorganic anion transport GO:0015698 109 75 0,000 0,12396744 0,12891093 ! lymphocyte differentiation GO:0030098 135 75 0,000 0,12396744 0,12885446 ! regulation of catabolic process GO:0009894 114 75 0,000 0,12396744 0,12879805 ! phospholipid biosynthetic process GO:0008654 109 76 0,000 0,12551497 0,1303488 ! phosphoinositide-mediated signaling GO:0048015 122 76 0,000 0,12551497 0,13029178 ! cell-substrate adhesion GO:0031589 141 76 0,000 0,12551497 0,13023481 ! regulation of Ras GTPase activity GO:0032318 125 76 0,000 0,12551497 0,13017789 ! negative regulation of transport GO:0051051 122 77 0,000 0,12705984 0,13172258 ! cellular lipid catabolic process GO:0044242 117 77 0,000 0,12705984 0,13166506 ! response to nutrient GO:0007584 114 77 0,000 0,12705984 0,13160759 ! monosaccharide catabolic process GO:0046365 104 77 0,000 0,12705984 0,13155017 ! regulation of blood pressure GO:0008217 119 78 0,000 0,12860206 0,13308883 ! muscle cell differentiation GO:0042692 117 78 0,000 0,12860206 0,13303081 ! amine transport GO:0015837 115 78 0,000 0,12860206 0,13297285 ! antigen processing and presentation GO:0019882 114 78 0,000 0,12860206 0,13291493 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 123 80 0,000 0,13167856 0,13603536 ! regulation of DNA binding GO:0051101 130 80 0,000 0,13167856 0,13597616 ! tube morphogenesis GO:0035239 140 80 0,000 0,13167856 0,13591702 ! intracellular protein transmembrane transport GO:0065002 115 80 0,000 0,13167856 0,13585792 ! protein ubiquitination GO:0016567 135 80 0,000 0,13167856 0,13579888 ! negative regulation of organelle organization GO:0010639 136 80 0,000 0,13167856 0,13573989 ! regulation of transmission of nerve impulse GO:0051969 126 80 0,000 0,13167856 0,13568095 ! response to steroid hormone stimulus GO:0048545 129 80 0,000 0,13167856 0,13562206 ! cellular response to hormone stimulus GO:0032870 125 80 0,000 0,13167856 0,13556322 ! blood coagulation GO:0007596 129 81 0,000 0,13321285 0,1370833 GO:0050817|coagulation, ! amine biosynthetic process GO:0009309 108 81 0,000 0,13321285 0,13702388 ! oxidative phosphorylation GO:0006119 110 81 0,000 0,13321285 0,13696451 ! nitrogen compound catabolic process GO:0044270 125 81 0,000 0,13321285 0,1369052 ! response to hypoxia GO:0001666 155 81 0,000 0,13321285 0,13684593 ! regulation of protein transport GO:0051223 123 81 0,000 0,13321285 0,13678671 GO:0070201|regulation of establishment of protein localization, ! neuropeptide signaling pathway GO:0007218 101 82 0,000 0,13474451 0,13829962 ! regulation of cell morphogenesis GO:0022604 155 82 0,000 0,13474451 0,13823983 ! cholesterol metabolic process GO:0008203 120 83 0,000 0,13627354 0,1397481 ! response to oxygen levels GO:0070482 160 83 0,000 0,13627354 0,13968773 ! regulation of cell cycle process GO:0010564 139 83 0,000 0,13627354 0,13962742 ! cofactor biosynthetic process GO:0051188 108 83 0,000 0,13627354 0,13956716 ! digestion GO:0007586 111 84 0,000 0,13779994 0,14106957 ! regulation of neurological system process GO:0031644 133 84 0,000 0,13779994 0,14100874 ! ATP biosynthetic process GO:0006754 131 84 0,000 0,13779994 0,14094796 ! biogenic amine metabolic process GO:0006576 128 85 0,000 0,13932372 0,14244515 ! T cell activation GO:0042110 154 85 0,000 0,13932372 0,14238381 ! sex differentiation GO:0007548 126 85 0,000 0,13932372 0,14232251 ! protein import into nucleus GO:0006606 145 85 0,000 0,13932372 0,14226127 ! one-carbon metabolic process GO:0006730 126 85 0,000 0,13932372 0,14220009 ! hemostasis GO:0007599 138 87 0,000 0,14236345 0,14524009 ! regulation of defense response GO:0031347 135 87 0,000 0,14236345 0,14517768 ! tRNA metabolic process GO:0006399 110 87 0,000 0,14236345 0,14511532 ! sensory perception of chemical stimulus GO:0007606 108 87 0,000 0,14236345 0,14505301 ! gland development GO:0048732 170 87 0,000 0,14236345 0,14499076 ! vitamin metabolic process GO:0006766 117 87 0,000 0,14236345 0,14492855 ! forebrain development GO:0030900 151 87 0,000 0,14236345 0,14486641 ! regulation of membrane potential GO:0042391 144 88 0,000 0,14387939 0,14634625 ! nucleosome assembly GO:0006334 113 89 0,000 0,14539274 0,14782218 GO:0031497|chromatin assembly, ! regulation of DNA metabolic process GO:0051052 152 90 0,000 0,14690348 0,14929421 ! skeletal muscle tissue development GO:0007519 135 90 0,000 0,14690348 0,1492303 GO:0060538|skeletal muscle organ development, ! transcription initiation GO:0006352 128 90 0,000 0,14690348 0,14916644 ! regulation of GTPase activity GO:0043087 149 90 0,000 0,14690348 0,14910264 ! nuclear import GO:0051170 153 90 0,000 0,14690348 0,14903889 ! regulation of protein localization GO:0032880 141 90 0,000 0,14690348 0,1489752 ! carboxylic acid catabolic process GO:0046395 132 91 0,000 0,14841164 0,15044033 GO:0016054|organic acid catabolic process, ! detection of stimulus GO:0051606 123 91 0,000 0,14841164 0,15037609 ! protein localization in nucleus GO:0034504 161 92 0,000 0,1499172 0,15183675 ! sterol metabolic process GO:0016125 136 92 0,000 0,1499172 0,15177197 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 141 93 0,000 0,15142017 0,15322817 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein-DNA complex assembly GO:0065004 119 93 0,000 0,15142017 0,15316286 ! rRNA processing GO:0006364 124 93 0,000 0,15142017 0,1530976 ! positive regulation of MAP kinase activity GO:0043406 143 93 0,000 0,15142017 0,1530324 ! anterior/posterior pattern formation GO:0009952 141 93 0,000 0,15142017 0,15296725 ! negative regulation of multicellular organismal process GO:0051241 150 93 0,000 0,15142017 0,15290216 ! leukocyte differentiation GO:0002521 165 94 0,000 0,15292057 0,15435155 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 94 0,000 0,15292057 0,15428593 ! ribonucleoside triphosphate biosynthetic process GO:0009201 142 94 0,000 0,15292057 0,15422036 ! rRNA metabolic process GO:0016072 125 94 0,000 0,15292057 0,15415484 ! regulation of cell adhesion GO:0030155 187 94 0,000 0,15292057 0,15408939 ! hormone metabolic process GO:0042445 135 94 0,000 0,15292057 0,15402398 ! protein processing GO:0016485 127 94 0,000 0,15292057 0,15395864 ! nucleoside triphosphate biosynthetic process GO:0009142 143 95 0,000 0,15441838 0,15540069 ! anatomical structure homeostasis GO:0060249 152 95 0,000 0,15441838 0,15533481 ! ATP metabolic process GO:0046034 150 96 0,000 0,15591363 0,15677247 ! nucleosome organization GO:0034728 126 96 0,000 0,15591363 0,15670607 ! protein modification by small protein conjugation GO:0032446 153 96 0,000 0,15591363 0,15663973 ! female pregnancy GO:0007565 148 96 0,000 0,15591363 0,15657344 ! regulation of neurogenesis GO:0050767 179 97 0,000 0,1574063 0,15800556 ! reproductive developmental process GO:0003006 149 97 0,000 0,1574063 0,15793875 ! response to virus GO:0009615 141 98 0,000 0,15889641 0,15936652 ! regulation of T cell activation GO:0050863 155 98 0,000 0,15889641 0,15929919 ! regulation of binding GO:0051098 164 99 0,000 0,16038396 0,16072261 ! electron transport chain GO:0022900 135 99 0,000 0,16038396 0,16065477 ! glycerophospholipid metabolic process GO:0006650 143 99 0,000 0,16038396 0,16058698 ! cell fate commitment GO:0045165 165 99 0,000 0,16038396 0,16051925 ! positive regulation of immune response GO:0050778 143 99 0,000 0,16038396 0,16045158 ! sulfur metabolic process GO:0006790 136 99 0,000 0,16038396 0,16038396