pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5501-6-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 5 5 3,000 5,252E-11 1,208E-07 ! natural killer cell mediated immunity GO:0002228 13 9 3,000 1,316E-09 1,514E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 5,000 1,596E-09 1,223E-06 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 5,000 2,136E-09 1,228E-06 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 5,000 2,136E-09 9,824E-07 ! positive regulation of ligase activity GO:0051351 99 69 5,000 3,083E-09 1,182E-06 ! leukocyte mediated cytotoxicity GO:0001909 17 11 3,000 3,439E-09 1,13E-06 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 5,000 3,674E-09 1,056E-06 ! regulation of ligase activity GO:0051340 114 75 5,000 5,138E-09 1,313E-06 ! cell killing GO:0001906 20 14 3,000 1,039E-08 2,39E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 3,855E-08 8,061E-06 ! polyol catabolic process GO:0046174 7 5 2,000 6,112E-08 1,172E-05 GO:0019405|alditol catabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 6,154E-08 1,089E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 4,000 9,634E-08 1,583E-05 ! spindle organization GO:0007051 37 30 3,000 2,785E-07 4,27E-05 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 4,000 3,795E-07 5,456E-05 GO:0010498|proteasomal protein catabolic process, ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 4,848E-07 6,559E-05 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 5,454E-07 6,969E-05 ! interphase GO:0051325 159 88 4,000 6,119E-07 7,407E-05 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 1,001E-06 1,151E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 1,233E-06 1,35E-04 ! fructose metabolic process GO:0006000 20 16 2,000 3,375E-06 3,528E-04 ! lymphocyte mediated immunity GO:0002449 88 62 3,000 5,432E-06 5,432E-04 ! alditol metabolic process GO:0019400 24 20 2,000 6,835E-06 6,55E-04 ! leukocyte mediated immunity GO:0002443 99 71 3,000 9,35E-06 8,602E-04 ! sperm motility GO:0030317 27 24 2,000 1,207E-05 1,068E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 2,165E-05 1,845E-03 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 2,928E-05 2,405E-03 ! polyol metabolic process GO:0019751 44 34 2,000 3,524E-05 2,795E-03 ! alcohol biosynthetic process GO:0046165 45 38 2,000 4,942E-05 3,789E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 5,159E-05 3,827E-03 GO:0046530|photoreceptor cell differentiation, ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 5,773E-05 4,149E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,214E-05 5,028E-03 ! microtubule bundle formation GO:0001578 8 7 1,000 7,214E-05 4,88E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 7,214E-05 4,74E-03 ! response to UV GO:0009411 75 46 2,000 8,802E-05 5,623E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 9,607E-05 5,972E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 9,607E-05 5,815E-03 ! keratinocyte proliferation GO:0043616 12 8 1,000 9,607E-05 5,666E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 1,234E-04 7,094E-03 ! establishment of cell polarity GO:0030010 12 9 1,000 1,234E-04 6,921E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,54E-04 8,435E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,673E-04 8,947E-03 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,762E-04 9,209E-03 ! Golgi vesicle budding GO:0048194 17 11 1,000 1,88E-04 9,611E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 2,000 1,949E-04 9,744E-03 ! negative regulation of ligase activity GO:0051352 91 61 2,000 2,047E-04 0,01001684 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 2,000 2,047E-04 9,808E-03 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,254E-04 0,01057906 ! negative regulation of caspase activity GO:0043154 20 14 1,000 3,1E-04 0,01426081 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,1E-04 0,01398118 ! positive regulation of cell size GO:0045793 20 15 1,000 3,573E-04 0,01580322 ! skin development GO:0043588 25 15 1,000 3,573E-04 0,01550504 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 4,076E-04 0,01735966 ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,078E-04 0,01705552 GO:0030968|endoplasmic reticulum unfolded protein response, ! alcohol catabolic process GO:0046164 104 80 2,000 4,56E-04 0,01872923 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,617E-04 0,01862934 ! membrane budding GO:0006900 29 17 1,000 4,617E-04 0,01830815 ! cell-cell junction organization GO:0045216 25 17 1,000 4,617E-04 0,01799784 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 5,188E-04 0,01988661 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 5,188E-04 0,0195606 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 5,791E-04 0,02148385 ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,427E-04 0,02346431 ! carbohydrate catabolic process GO:0016052 121 93 2,000 7,083E-04 0,02545549 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,095E-04 0,0251066 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 7,095E-04 0,0247262 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 7,095E-04 0,02435715 ! response to light stimulus GO:0009416 153 96 2,000 7,769E-04 0,02627793 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 7,796E-04 0,02598556 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 8,528E-04 0,0280207 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 8,528E-04 0,02762605 ! osteoblast differentiation GO:0001649 40 23 1,000 8,528E-04 0,02724235 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 8,528E-04 0,02686917 ! fat cell differentiation GO:0045444 37 24 1,000 9,292E-04 0,0288816 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,009E-03 0,03093794 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of B cell activation GO:0050864 42 28 1,000 1,267E-03 0,03833294 ! protein targeting to membrane GO:0006612 53 29 1,000 1,359E-03 0,0405898 ! eye morphogenesis GO:0048592 51 29 1,000 1,359E-03 0,04006942 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 1,759E-03 0,0512082 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 63 33 1,000 1,759E-03 0,0505681 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,759E-03 0,0499438 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 1,867E-03 0,05235638 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 1,867E-03 0,05172558 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,977E-03 0,05414349 ! glycogen metabolic process GO:0005977 48 35 1,000 1,977E-03 0,05350651 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,977E-03 0,05288434 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 49 36 1,000 2,091E-03 0,05528635 GO:0006073|cellular glucan metabolic process, ! response to calcium ion GO:0051592 58 40 1,000 2,577E-03 0,06735366 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,577E-03 0,06659688 ! energy reserve metabolic process GO:0006112 59 41 1,000 2,706E-03 0,06915267 ! vesicle organization GO:0016050 79 43 1,000 2,973E-03 0,07513819 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,111E-03 0,07776893 ! positive regulation of cell cycle GO:0045787 77 45 1,000 3,252E-03 0,08041621 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,542E-03 0,08666952 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 3,692E-03 0,08938049 ! positive regulation of growth GO:0045927 67 50 1,000 4E-03 0,0958296 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,993E-03 0,11839075 ! actin filament organization GO:0007015 95 59 1,000 5,528E-03 0,12973598 ! negative regulation of cell growth GO:0030308 106 62 1,000 6,088E-03 0,14143637 ! negative regulation of cell size GO:0045792 108 64 1,000 6,475E-03 0,14892733 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 6,475E-03 0,1474528 ! regulation of caspase activity GO:0043281 97 65 1,000 6,673E-03 0,15046541 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 7,076E-03 0,15801724 ! response to metal ion GO:0010038 103 70 1,000 7,702E-03 0,17033595 ! eye development GO:0001654 111 70 1,000 7,702E-03 0,16871371 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 7,702E-03 0,16712207 ! steroid biosynthetic process GO:0006694 94 71 1,000 7,916E-03 0,17015908 ! regulation of peptidase activity GO:0052547 106 72 1,000 8,133E-03 0,17319671 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 8,133E-03 0,17160775 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 8,352E-03 0,17463259 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 8,574E-03 0,17765784 ! response to inorganic substance GO:0010035 115 75 1,000 8,798E-03 0,18068326 ! negative regulation of growth GO:0045926 123 75 1,000 8,798E-03 0,1790843 ! response to unfolded protein GO:0006986 99 76 1,000 9,026E-03 0,18209718 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 9,256E-03 0,18511005 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,404E-03 0,18645438 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,404E-03 0,18486075 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,404E-03 0,18329413 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,404E-03 0,18175385 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,404E-03 0,18023923 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,404E-03 0,17874965 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,404E-03 0,17728449 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,404E-03 0,17584315 ! sleep GO:0030431 11 5 0,000 9,404E-03 0,17442506 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,404E-03 0,17302966 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,404E-03 0,17165641 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,404E-03 0,17030478 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,404E-03 0,16897428 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,404E-03 0,1676644 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,404E-03 0,16637467 ! tongue development GO:0043586 6 5 0,000 9,404E-03 0,16510464 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,404E-03 0,16385385 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,404E-03 0,16262186 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,404E-03 0,16140827 ! cobalt ion transport GO:0006824 9 5 0,000 9,404E-03 0,16021265 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,404E-03 0,15903462 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,404E-03 0,15787378 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,404E-03 0,15672977 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,404E-03 0,15560221 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,404E-03 0,15449077 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,404E-03 0,15339509 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,404E-03 0,15231484 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,404E-03 0,1512497 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,404E-03 0,15019936 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,404E-03 0,1491635 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,404E-03 0,14814183 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,404E-03 0,14713407 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,404E-03 0,14613992 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,404E-03 0,14515911 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,404E-03 0,14419138 ! malate metabolic process GO:0006108 7 5 0,000 9,404E-03 0,14323647 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,404E-03 0,14229413 ! behavioral response to pain GO:0048266 7 5 0,000 9,404E-03 0,1413641 ! clathrin coat assembly GO:0048268 11 5 0,000 9,404E-03 0,14044615 ! phototransduction, visible light GO:0007603 6 5 0,000 9,404E-03 0,13954005 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,404E-03 0,13864556 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,404E-03 0,13776247 ! mating behavior GO:0007617 6 5 0,000 9,404E-03 0,13689055 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,404E-03 0,13602961 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,404E-03 0,13517942 ! rhythmic behavior GO:0007622 12 5 0,000 9,404E-03 0,1343398 ! copulation GO:0007620 7 5 0,000 9,404E-03 0,13351054 ! glial cell fate commitment GO:0021781 12 5 0,000 9,404E-03 0,13269146 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,404E-03 0,13188236 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,404E-03 0,13108308 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,404E-03 0,13029342 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,404E-03 0,12951322 ! apoptotic cell clearance GO:0043277 13 5 0,000 9,404E-03 0,12874231 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,404E-03 0,12798052 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,404E-03 0,12722769 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,404E-03 0,12648367 ! response to protozoan GO:0001562 9 5 0,000 9,404E-03 0,1257483 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,404E-03 0,12502143 ! lymph vessel development GO:0001945 7 5 0,000 9,404E-03 0,12430292 ! endochondral ossification GO:0001958 12 5 0,000 9,404E-03 0,12359262 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,404E-03 0,12289038 ! parathyroid gland development GO:0060017 8 5 0,000 9,404E-03 0,12219609 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,404E-03 0,12150959 ! anagen GO:0042640 6 5 0,000 9,404E-03 0,12083077 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,404E-03 0,12015949 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,404E-03 0,11949562 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,404E-03 0,11883905 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,404E-03 0,11818966 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,404E-03 0,11754732 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,404E-03 0,11691193 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 9,404E-03 0,11628337 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,404E-03 0,11566154 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,404E-03 0,11504632 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,404E-03 0,11443761 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,404E-03 0,1138353 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,404E-03 0,11323931 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,404E-03 0,11264952 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,404E-03 0,11206584 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,404E-03 0,11148818 ! ovulation GO:0030728 6 5 0,000 9,404E-03 0,11091645 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,404E-03 0,11035055 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,404E-03 0,10979039 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,404E-03 0,1092359 ! response to pH GO:0009268 9 5 0,000 9,404E-03 0,10868697 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 9,404E-03 0,10814354 ! proline biosynthetic process GO:0006561 6 5 0,000 9,404E-03 0,10760551 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,404E-03 0,10707281 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,404E-03 0,10654536 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,404E-03 0,10602308 ! polyol biosynthetic process GO:0046173 5 5 0,000 9,404E-03 0,10550589 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,404E-03 0,10499373 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,404E-03 0,10448651 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,404E-03 0,10398417 ! nerve growth factor processing GO:0032455 7 5 0,000 9,404E-03 0,10348664 ! urea metabolic process GO:0019627 6 5 0,000 9,404E-03 0,10299385 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,404E-03 0,10250572 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,404E-03 0,10202221 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,404E-03 0,10154323 ! neutrophil activation GO:0042119 5 5 0,000 9,404E-03 0,10106873 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,404E-03 0,10059864 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,404E-03 0,10013291 ! response to food GO:0032094 5 5 0,000 9,404E-03 0,09967146 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,404E-03 0,09921426 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,404E-03 0,09876122 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,404E-03 0,09831231 ! forebrain neuron development GO:0021884 7 5 0,000 9,404E-03 0,09786746 ! melanosome organization GO:0032438 7 5 0,000 9,404E-03 0,09742661 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,404E-03 0,09698972 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,404E-03 0,09655673 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,404E-03 0,09612759 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,404E-03 0,09570225 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,404E-03 0,09528065 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,404E-03 0,09486275 ! nucleoside transport GO:0015858 6 5 0,000 9,404E-03 0,09444851 ! nucleoside salvage GO:0043174 7 5 0,000 9,404E-03 0,09403786 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,404E-03 0,09363077 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,404E-03 0,09322719 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,404E-03 0,09282707 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,404E-03 0,09243037 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,404E-03 0,09203705 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,404E-03 0,09164707 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,404E-03 0,09126037 ! depyrimidination GO:0045008 8 5 0,000 9,404E-03 0,09087692 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,404E-03 0,09049668 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,404E-03 0,09011962 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,404E-03 0,08974568 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,404E-03 0,08937483 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,404E-03 0,08900703 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,404E-03 0,08864224 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,404E-03 0,08828044 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,404E-03 0,08792158 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,404E-03 0,08756562 ! monocyte differentiation GO:0030224 8 5 0,000 9,404E-03 0,08721253 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,404E-03 0,08686228 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,404E-03 0,08651483 ! centrosome duplication GO:0051298 5 5 0,000 9,404E-03 0,08617015 ! response to UV-C GO:0010225 6 5 0,000 9,404E-03 0,08582821 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,404E-03 0,08548896 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,404E-03 0,08515239 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,404E-03 0,08481846 ! regulation of dendrite development GO:0050773 12 5 0,000 9,404E-03 0,08448714 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,404E-03 0,0841584 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,404E-03 0,0838322 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,404E-03 0,08350852 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,404E-03 0,08318734 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,404E-03 0,08286861 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,404E-03 0,08255232 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,404E-03 0,08223843 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,404E-03 0,08192692 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,404E-03 0,08161776 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,404E-03 0,08131093 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,404E-03 0,0810064 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,404E-03 0,08070413 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,404E-03 0,08040412 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,404E-03 0,08010632 ! neural tube patterning GO:0021532 6 5 0,000 9,404E-03 0,07981073 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,404E-03 0,07951731 ! histone demethylation GO:0016577 9 5 0,000 9,404E-03 0,07922604 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,404E-03 0,07893689 ! regulation of sterol transport GO:0032371 7 5 0,000 9,404E-03 0,07864985 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,404E-03 0,07836488 ! enteric nervous system development GO:0048484 8 5 0,000 9,404E-03 0,07808198 ! establishment of planar polarity GO:0001736 6 5 0,000 9,404E-03 0,07780111 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,404E-03 0,07752225 ! muscle cell proliferation GO:0033002 8 5 0,000 9,404E-03 0,07724538 ! transcription termination GO:0006353 8 5 0,000 9,404E-03 0,07697049 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,404E-03 0,07669754 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,404E-03 0,07642653 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,404E-03 0,07615742 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,404E-03 0,0758902 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 9,404E-03 0,07562485 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,404E-03 0,07536135 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,404E-03 0,07509968 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,404E-03 0,07483982 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,404E-03 0,07458175 ! apical protein localization GO:0045176 6 5 0,000 9,404E-03 0,07432546 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 9,404E-03 0,07407092 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,404E-03 0,07381811 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,404E-03 0,07356703 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,404E-03 0,07331765 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,404E-03 0,07306996 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,404E-03 0,07282393 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,404E-03 0,07257956 ! glial cell migration GO:0008347 10 5 0,000 9,404E-03 0,07233681 ! determination of adult lifespan GO:0008340 8 5 0,000 9,404E-03 0,07209569 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,404E-03 0,07185617 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,404E-03 0,07161824 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,404E-03 0,07138187 ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,404E-03 0,07114706 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,404E-03 0,0709138 ! neural plate development GO:0001840 6 5 0,000 9,404E-03 0,07068205 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 9,404E-03 0,07045182 ! regulation of sensory perception GO:0051931 6 5 0,000 9,404E-03 0,07022308 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,404E-03 0,06999582 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,404E-03 0,06977002 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 9,404E-03 0,06954568 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,404E-03 0,06932278 ! sensory cilium assembly GO:0035058 6 5 0,000 9,404E-03 0,0691013 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,404E-03 0,06888123 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,404E-03 0,06866256 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,404E-03 0,06844528 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,404E-03 0,06822936 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,404E-03 0,0680148 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,404E-03 0,06780159 ! organ regeneration GO:0031100 7 5 0,000 9,404E-03 0,06758971 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,404E-03 0,06737915 ! carnitine metabolic process GO:0009437 5 5 0,000 9,404E-03 0,0671699 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 9,404E-03 0,06696194 ! cellular anion homeostasis GO:0030002 6 5 0,000 9,404E-03 0,06675527 GO:0055081|anion homeostasis, ! positive regulation of protein modification process GO:0031401 107 78 1,000 9,488E-03 0,06714534 ! regulation of cyclase activity GO:0031279 132 78 1,000 9,488E-03 0,06693937 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 9,723E-03 0,06838774 ! cellular respiration GO:0045333 107 79 1,000 9,723E-03 0,06817924 ! regulation of lyase activity GO:0051339 133 79 1,000 9,723E-03 0,06797201 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,01020076 0,0710962 ! response to protein stimulus GO:0051789 111 81 1,000 0,01020076 0,07088141 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01020076 0,07066791 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01044352 0,07213243 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,01068884 0,0736058 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! Golgi vesicle transport GO:0048193 138 85 1,000 0,01118712 0,07680712 ! tRNA transcription GO:0009304 11 6 0,000 0,01127423 0,07717476 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01127423 0,07694575 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01127423 0,0767181 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01127423 0,0764918 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01127423 0,07626682 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01127423 0,07604316 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01127423 0,07582082 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01127423 0,07559976 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01127423 0,07538 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01127423 0,0751615 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01127423 0,07494427 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01127423 0,0747283 ! prostate gland development GO:0030850 9 6 0,000 0,01127423 0,07451356 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01127423 0,07430005 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01127423 0,07408777 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01127423 0,07387669 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01127423 0,07366682 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01127423 0,07345813 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01127423 0,07325062 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01127423 0,07304428 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01127423 0,0728391 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01127423 0,07263507 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01127423 0,07243218 ! neuron adhesion GO:0007158 9 6 0,000 0,01127423 0,07223042 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01127423 0,07202978 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01127423 0,07183025 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01127423 0,07163182 ! signal peptide processing GO:0006465 8 6 0,000 0,01127423 0,07143449 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01127423 0,07123824 ! mRNA stabilization GO:0048255 15 6 0,000 0,01127423 0,07104307 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01127423 0,07084896 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01127423 0,07065591 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01127423 0,07046391 ! opsonization GO:0008228 8 6 0,000 0,01127423 0,07027295 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01127423 0,07008302 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01127423 0,06989412 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01127423 0,06970623 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01127423 0,06951935 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01127423 0,06933347 ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01127423 0,06914858 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01127423 0,06896468 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01127423 0,06878175 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01127423 0,06859979 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01127423 0,06841878 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01127423 0,06823873 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01127423 0,06805963 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01127423 0,06788146 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01127423 0,06770423 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01127423 0,06752791 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01127423 0,06735252 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01127423 0,06717803 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01127423 0,06700444 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01127423 0,06683175 ! thymic T cell selection GO:0045061 12 6 0,000 0,01127423 0,06665995 ! protein lipoylation GO:0009249 10 6 0,000 0,01127423 0,06648902 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01127423 0,06631897 ! pigment granule organization GO:0048753 11 6 0,000 0,01127423 0,06614979 ! drug transport GO:0015893 6 6 0,000 0,01127423 0,06598147 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01127423 0,06581401 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01127423 0,06564739 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01127423 0,06548161 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01127423 0,06531667 ! histidine metabolic process GO:0006547 6 6 0,000 0,01127423 0,06515256 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01127423 0,06498927 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01127423 0,0648268 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01127423 0,06466513 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01127423 0,06450428 ! adenohypophysis development GO:0021984 10 6 0,000 0,01127423 0,06434422 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01127423 0,06418495 ! hyperosmotic response GO:0006972 8 6 0,000 0,01127423 0,06402647 ! microtubule nucleation GO:0007020 10 6 0,000 0,01127423 0,06386877 ! ER overload response GO:0006983 7 6 0,000 0,01127423 0,06371184 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01127423 0,06355568 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01127423 0,06340029 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01127423 0,06324566 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01127423 0,06309177 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01127423 0,06293864 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01127423 0,06278624 ! response to dietary excess GO:0002021 7 6 0,000 0,01127423 0,06263459 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01127423 0,06248366 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01127423 0,06233346 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01127423 0,06218398 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01127423 0,06203521 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01127423 0,06188716 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01127423 0,06173981 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01127423 0,06159316 ! neuron apoptosis GO:0051402 8 6 0,000 0,01127423 0,0614472 ! organic alcohol transport GO:0015850 9 6 0,000 0,01127423 0,06130194 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01127423 0,06115736 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01127423 0,06101346 ! male sex determination GO:0030238 9 6 0,000 0,01127423 0,06087023 ! carnitine transport GO:0015879 8 6 0,000 0,01127423 0,06072768 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01127423 0,06058579 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01127423 0,06044457 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01127423 0,060304 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01127423 0,06016408 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01127423 0,06002481 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01127423 0,05988619 ! parturition GO:0007567 12 6 0,000 0,01127423 0,0597482 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01127423 0,05961085 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01127423 0,05947413 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01127423 0,05933803 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01127423 0,05920255 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01127423 0,0590677 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01127423 0,05893345 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01127423 0,05879982 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01127423 0,05866679 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01127423 0,05853435 ! macrophage differentiation GO:0030225 10 6 0,000 0,01127423 0,05840252 ! astrocyte development GO:0014002 14 6 0,000 0,01127423 0,05827128 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01127423 0,05814063 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01127423 0,05801056 ! interaction with symbiont GO:0051702 8 6 0,000 0,01127423 0,05788107 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01127423 0,05775216 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01127423 0,05762382 ! eating behavior GO:0042755 6 6 0,000 0,01127423 0,05749605 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01127423 0,05736885 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01127423 0,05724221 ! response to copper ion GO:0046688 9 6 0,000 0,01127423 0,05711612 ! DNA topological change GO:0006265 8 6 0,000 0,01127423 0,05699059 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01127423 0,05686561 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01127423 0,05674118 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01127423 0,05661729 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01127423 0,05649394 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01127423 0,05637113 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01127423 0,05624885 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01127423 0,0561271 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01127423 0,05600587 ! gas homeostasis GO:0033483 11 6 0,000 0,01127423 0,05588517 ! hair follicle maturation GO:0048820 7 6 0,000 0,01127423 0,05576499 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01127423 0,05564532 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01127423 0,05552616 ! Schwann cell development GO:0014044 14 6 0,000 0,01127423 0,05540752 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01127423 0,05528938 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01127423 0,05517174 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01127423 0,05505461 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01127423 0,05493796 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01127423 0,05482182 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01127423 0,05470616 ! histone ubiquitination GO:0016574 7 6 0,000 0,01127423 0,05459099 ! regulation of meiosis GO:0040020 10 6 0,000 0,01127423 0,0544763 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01127423 0,05436209 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01127423 0,05424837 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01127423 0,05413511 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01127423 0,05402233 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01127423 0,05391002 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01127423 0,05379817 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01127423 0,05368679 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01127423 0,05357587 ! receptor internalization GO:0031623 9 6 0,000 0,01127423 0,0534654 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01127423 0,05335539 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01127423 0,05324583 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01127423 0,05313672 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01127423 0,05302806 ! protein deubiquitination GO:0016579 8 6 0,000 0,01127423 0,05291983 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01127423 0,05281206 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01127423 0,05270471 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01127423 0,05259781 ! axonal fasciculation GO:0007413 9 6 0,000 0,01127423 0,05249133 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01127423 0,05238529 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01127423 0,05227968 ! midbrain development GO:0030901 6 6 0,000 0,01127423 0,05217449 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01127423 0,05206972 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01127423 0,05196537 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01127423 0,05186144 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01127423 0,05175792 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01127423 0,05165482 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01127423 0,05155213 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01127423 0,05144984 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01127423 0,05134796 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01127423 0,05124648 ! adult feeding behavior GO:0008343 6 6 0,000 0,01127423 0,0511454 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01127423 0,05104472 ! blastocyst growth GO:0001832 15 6 0,000 0,01127423 0,05094444 ! pigment granule transport GO:0051904 12 6 0,000 0,01127423 0,05084455 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01127423 0,05074505 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01127423 0,05064594 ! catecholamine transport GO:0051937 7 6 0,000 0,01127423 0,05054721 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01127423 0,05044887 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01127423 0,05035091 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01127423 0,05025333 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01127423 0,05015613 ! protein prenylation GO:0018342 10 6 0,000 0,01127423 0,0500593 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01127423 0,04996285 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01127423 0,04986677 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01127423 0,04977105 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01127423 0,04967571 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01127423 0,04958072 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,01144006 0,05021402 ! cell cycle arrest GO:0007050 150 86 1,000 0,01144006 0,05011837 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,01169552 0,05114012 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,01221396 0,05330571 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01314124 0,05724404 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01314124 0,05713583 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01314124 0,05702802 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01314124 0,05692063 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01314124 0,05681363 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01314124 0,05670704 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01314124 0,05660085 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01314124 0,05649505 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01314124 0,05638965 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01314124 0,05628464 ! reproductive behavior GO:0019098 12 7 0,000 0,01314124 0,05618002 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01314124 0,05607579 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01314124 0,05597195 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01314124 0,05586849 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01314124 0,05576541 ! oligopeptide transport GO:0006857 11 7 0,000 0,01314124 0,05566271 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01314124 0,05556039 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01314124 0,05545845 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01314124 0,05535687 ! RNA methylation GO:0001510 11 7 0,000 0,01314124 0,05525567 ! pericardium development GO:0060039 8 7 0,000 0,01314124 0,05515484 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01314124 0,05505438 ! fibril organization GO:0043206 13 7 0,000 0,01314124 0,05495428 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01314124 0,05485454 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01314124 0,05475517 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01314124 0,05465615 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01314124 0,0545575 ! lipoprotein transport GO:0042953 9 7 0,000 0,01314124 0,05445919 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01314124 0,05436125 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01314124 0,05426365 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01314124 0,0541664 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01314124 0,0540695 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01314124 0,05397295 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01314124 0,05387674 ! chemosensory behavior GO:0007635 9 7 0,000 0,01314124 0,05378088 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01314124 0,05368535 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01314124 0,05359017 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01314124 0,05349532 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01314124 0,0534008 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01314124 0,05330662 ! reflex GO:0060004 12 7 0,000 0,01314124 0,05321277 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01314124 0,05311925 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01314124 0,05302606 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01314124 0,05293319 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01314124 0,05284065 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01314124 0,05274843 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01314124 0,05265654 ! spinal cord patterning GO:0021511 7 7 0,000 0,01314124 0,05256496 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01314124 0,0524737 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01314124 0,05238276 ! adrenal gland development GO:0030325 17 7 0,000 0,01314124 0,05229213 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01314124 0,05220182 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01314124 0,05211182 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01314124 0,05202212 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01314124 0,05193274 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01314124 0,05184366 ! endosome organization GO:0007032 10 7 0,000 0,01314124 0,05175489 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01314124 0,05166642 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01314124 0,05157825 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01314124 0,05149038 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01314124 0,05140281 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01314124 0,05131554 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01314124 0,05122856 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01314124 0,05114188 ! galactose metabolic process GO:0006012 10 7 0,000 0,01314124 0,0510555 ! vesicle fusion GO:0006906 15 7 0,000 0,01314124 0,0509694 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01314124 0,05088359 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01314124 0,05079807 ! organ growth GO:0035265 11 7 0,000 0,01314124 0,05071284 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01314124 0,05062789 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01314124 0,05054323 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01314124 0,05045885 ! retinol metabolic process GO:0042572 9 7 0,000 0,01314124 0,05037476 ! behavioral fear response GO:0001662 13 7 0,000 0,01314124 0,05029094 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01314124 0,0502074 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01314124 0,05012413 ! rRNA modification GO:0000154 12 7 0,000 0,01314124 0,05004115 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01314124 0,04995843 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01314124 0,049876 ! response to UV-B GO:0010224 11 7 0,000 0,01314124 0,04979383 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01314124 0,04971193 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01314124 0,0496303 ! intermediate filament organization GO:0045109 11 7 0,000 0,01314124 0,04954894 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01314124 0,04946784 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01314124 0,04938701 ! fibrinolysis GO:0042730 9 7 0,000 0,01314124 0,04930645 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01314124 0,04922615 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01314124 0,0491461 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01314124 0,04906632 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01314124 0,0489868 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01314124 0,04890753 ! response to tropane GO:0014073 13 7 0,000 0,01314124 0,04882852 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01314124 0,04874976 ! melanosome localization GO:0032400 10 7 0,000 0,01314124 0,04867126 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01314124 0,04859301 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01314124 0,04851501 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01314124 0,04843726 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01314124 0,04835976 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01314124 0,04828251 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01314124 0,04820551 ! mast cell activation GO:0045576 9 7 0,000 0,01314124 0,04812875 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01314124 0,04805223 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01314124 0,04797596 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01314124 0,04789993 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01314124 0,04782413 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01314124 0,04774858 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01314124 0,04767327 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01314124 0,04759819 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01314124 0,04752335 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01314124 0,04744875 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01314124 0,04737438 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01314124 0,04730024 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01314124 0,04722633 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01314124 0,04715266 ! response to tumor cell GO:0002347 12 7 0,000 0,01314124 0,04707921 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01314124 0,04700599 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01314124 0,046933 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01314124 0,04686024 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01314124 0,0467877 ! diuresis GO:0030146 12 7 0,000 0,01314124 0,04671538 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01314124 0,04664329 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01314124 0,04657142 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01314124 0,04649977 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01314124 0,04642835 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01314124 0,04635714 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01314124 0,04628615 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01314124 0,04621537 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01314124 0,04614481 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01314124 0,04607447 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01314124 0,04600434 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01314124 0,04593443 ! lymph node development GO:0048535 9 7 0,000 0,01314124 0,04586472 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01314124 0,04579523 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01314124 0,04572595 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01314124 0,04565688 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01314124 0,04558801 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01314124 0,04551936 ! ATP catabolic process GO:0006200 10 7 0,000 0,01314124 0,04545091 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01314124 0,04538266 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01314124 0,04531462 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01314124 0,04524679 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01314124 0,04517915 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01314124 0,04511172 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01314124 0,04504449 ! muscle adaptation GO:0043500 12 7 0,000 0,01314124 0,04497746 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01314124 0,04491063 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01314124 0,044844 ! retina homeostasis GO:0001895 9 7 0,000 0,01314124 0,04477756 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01314124 0,04471132 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01314124 0,04464528 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01314124 0,04457943 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01314124 0,04451377 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01314124 0,04444831 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01314124 0,04438304 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01314124 0,04431797 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,01328064 0,04472252 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01500484 0,05045486 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01500484 0,0503812 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01500484 0,05030776 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01500484 0,05023453 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01500484 0,05016152 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01500484 0,05008871 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01500484 0,05001612 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01500484 0,04994374 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01500484 0,04987157 ! phosphate transport GO:0006817 10 8 0,000 0,01500484 0,0497996 ! N-glycan processing GO:0006491 12 8 0,000 0,01500484 0,04972784 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01500484 0,04965629 ! UTP metabolic process GO:0046051 8 8 0,000 0,01500484 0,04958495 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01500484 0,04951381 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01500484 0,04944287 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01500484 0,04937214 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01500484 0,04930161 ! succinate metabolic process GO:0006105 14 8 0,000 0,01500484 0,04923127 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01500484 0,04916114 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01500484 0,04909121 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01500484 0,04902148 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01500484 0,04895195 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01500484 0,04888261 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01500484 0,04881347 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01500484 0,04874453 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01500484 0,04867577 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01500484 0,04860722 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01500484 0,04853885 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01500484 0,04847068 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01500484 0,0484027 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01500484 0,04833491 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01500484 0,04826731 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01500484 0,04819989 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01500484 0,04813267 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01500484 0,04806563 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01500484 0,04799878 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01500484 0,04793212 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01500484 0,04786564 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01500484 0,04779934 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01500484 0,04773323 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01500484 0,0476673 ! melanin metabolic process GO:0006582 12 8 0,000 0,01500484 0,04760155 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01500484 0,04753598 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01500484 0,0474706 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01500484 0,04740539 ! macrophage activation GO:0042116 12 8 0,000 0,01500484 0,04734036 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01500484 0,04727551 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01500484 0,04721084 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01500484 0,04714634 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01500484 0,04708202 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01500484 0,04701788 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01500484 0,04695391 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01500484 0,04689011 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01500484 0,04682649 ! ruffle organization GO:0031529 11 8 0,000 0,01500484 0,04676304 ! osteoblast development GO:0002076 13 8 0,000 0,01500484 0,04669976 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01500484 0,04663665 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01500484 0,04657372 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01500484 0,04651095 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01500484 0,04644835 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01500484 0,04638592 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01500484 0,04632366 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01500484 0,04626156 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01500484 0,04619963 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01500484 0,04613787 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01500484 0,04607627 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01500484 0,04601483 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01500484 0,04595356 ! segment specification GO:0007379 10 8 0,000 0,01500484 0,04589245 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01500484 0,04583151 ! cellular extravasation GO:0045123 11 8 0,000 0,01500484 0,04577072 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01500484 0,0457101 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01500484 0,04564963 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01500484 0,04558933 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01500484 0,04552919 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01500484 0,0454692 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01500484 0,04540937 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01500484 0,0453497 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01500484 0,04529019 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01500484 0,04523083 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01500484 0,04517163 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01500484 0,04511258 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01500484 0,04505369 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01500484 0,04499495 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01500484 0,04493636 ! icosanoid secretion GO:0032309 12 8 0,000 0,01500484 0,04487792 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01500484 0,04481964 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01500484 0,04476151 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01500484 0,04470353 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01500484 0,0446457 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01500484 0,04458802 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01500484 0,04453048 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01500484 0,0444731 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01500484 0,04441586 ! sterol catabolic process GO:0016127 9 8 0,000 0,01500484 0,04435877 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01500484 0,04430183 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01500484 0,04424503 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01500484 0,04418838 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01500484 0,04413187 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01500484 0,04407551 ! prophase GO:0051324 11 8 0,000 0,01500484 0,04401929 ! S phase GO:0051320 8 8 0,000 0,01500484 0,04396321 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01500484 0,04390728 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01500484 0,04385149 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01500484 0,04379584 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01500484 0,04374033 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01500484 0,04368497 ! hormone catabolic process GO:0042447 13 8 0,000 0,01500484 0,04362974 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01500484 0,04357465 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01500484 0,0435197 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01500484 0,04346489 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01500484 0,04341022 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01500484 0,04335568 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01500484 0,04330128 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01500484 0,04324702 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01500484 0,0431929 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01500484 0,0431389 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01500484 0,04308505 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01500484 0,04303133 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01500484 0,04297774 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01500484 0,04292428 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01500484 0,04287096 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01500484 0,04281777 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01500484 0,04276471 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01686502 0,04800686 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01686502 0,04794752 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01686502 0,04788833 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01686502 0,04782928 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01686502 0,04777038 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01686502 0,04771162 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01686502 0,047653 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01686502 0,04759453 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01686502 0,04753621 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01686502 0,04747802 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01686502 0,04741998 ! GTP metabolic process GO:0046039 9 9 0,000 0,01686502 0,04736208 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01686502 0,04730432 ! social behavior GO:0035176 14 9 0,000 0,01686502 0,04724671 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01686502 0,04718923 ! artery development GO:0060840 19 9 0,000 0,01686502 0,04713189 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01686502 0,04707469 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01686502 0,04701763 ! response to pain GO:0048265 16 9 0,000 0,01686502 0,04696071 ! protein complex disassembly GO:0043241 17 9 0,000 0,01686502 0,04690392 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01686502 0,04684728 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01686502 0,04679077 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01686502 0,04673439 ! lung alveolus development GO:0048286 17 9 0,000 0,01686502 0,04667815 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01686502 0,04662205 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01686502 0,04656608 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01686502 0,04651025 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01686502 0,04645454 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01686502 0,04639898 ! protein targeting to ER GO:0045047 19 9 0,000 0,01686502 0,04634354 ! T cell selection GO:0045058 18 9 0,000 0,01686502 0,04628824 ! endoderm development GO:0007492 12 9 0,000 0,01686502 0,04623307 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01686502 0,04617803 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01686502 0,04612312 ! arginine catabolic process GO:0006527 10 9 0,000 0,01686502 0,04606834 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01686502 0,0460137 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01686502 0,04595918 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01686502 0,04590479 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01686502 0,04585053 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01686502 0,04579639 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01686502 0,04574239 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01686502 0,04568851 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01686502 0,04563476 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01686502 0,04558113 ! mannose metabolic process GO:0006013 9 9 0,000 0,01686502 0,04552763 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01686502 0,04547426 ! receptor clustering GO:0043113 15 9 0,000 0,01686502 0,04542101 ! epithelial cell development GO:0002064 10 9 0,000 0,01686502 0,04536789 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01686502 0,04531489 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01686502 0,04526201 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01686502 0,04520926 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01686502 0,04515663 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01686502 0,04510412 ! motor axon guidance GO:0008045 14 9 0,000 0,01686502 0,04505174 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01686502 0,04499947 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01686502 0,04494733 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01686502 0,04489531 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01686502 0,0448434 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01686502 0,04479162 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01686502 0,04473996 ! DNA ligation GO:0006266 14 9 0,000 0,01686502 0,04468842 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01686502 0,04463699 ! response to amine stimulus GO:0014075 13 9 0,000 0,01686502 0,04458568 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01686502 0,04453449 ! erythrocyte development GO:0048821 11 9 0,000 0,01686502 0,04448342 ! renal water homeostasis GO:0003091 14 9 0,000 0,01686502 0,04443247 ! postreplication repair GO:0006301 11 9 0,000 0,01686502 0,04438163 ! mRNA cleavage GO:0006379 13 9 0,000 0,01686502 0,04433091 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01686502 0,0442803 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01686502 0,04422981 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01686502 0,04417944 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01686502 0,04412918 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01686502 0,04407903 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01686502 0,044029 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01686502 0,04397908 ! acid secretion GO:0046717 14 9 0,000 0,01686502 0,04392927 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01686502 0,04387958 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01686502 0,04382999 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01686502 0,04378052 ! purine base metabolic process GO:0006144 18 9 0,000 0,01686502 0,04373117 ! oocyte differentiation GO:0009994 12 9 0,000 0,01686502 0,04368192 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01686502 0,04363278 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01686502 0,04358376 ! spleen development GO:0048536 15 9 0,000 0,01686502 0,04353484 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01686502 0,04348604 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01686502 0,04343734 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01686502 0,04338875 ! detection of calcium ion GO:0005513 13 9 0,000 0,01686502 0,04334027 ! blastocyst formation GO:0001825 12 9 0,000 0,01686502 0,0432919 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01686502 0,04324364 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01686502 0,04319548 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01686502 0,04314744 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01686502 0,04309949 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01686502 0,04305166 ! prepulse inhibition GO:0060134 14 9 0,000 0,01686502 0,04300393 ! embryonic placenta development GO:0001892 12 9 0,000 0,01686502 0,04295631 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01686502 0,04290879 ! insulin secretion GO:0030073 17 9 0,000 0,01686502 0,04286138 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01686502 0,04281407 ! response to nicotine GO:0035094 16 9 0,000 0,01686502 0,04276686 ! nucleus localization GO:0051647 15 9 0,000 0,01686502 0,04271976 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01686502 0,04267277 ! localization within membrane GO:0051668 15 9 0,000 0,01686502 0,04262587 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,0187218 0,04726688 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0187218 0,04721506 ! neuron fate specification GO:0048665 11 10 0,000 0,0187218 0,04716334 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,0187218 0,04711174 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,0187218 0,04706025 ! thyroid gland development GO:0030878 19 10 0,000 0,0187218 0,04700888 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,0187218 0,04695761 ! synapsis GO:0007129 13 10 0,000 0,0187218 0,04690646 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,0187218 0,04685542 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,0187218 0,04680449 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0187218 0,04675367 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,0187218 0,04670296 ! sulfate transport GO:0008272 12 10 0,000 0,0187218 0,04665236 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,0187218 0,04660187 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,0187218 0,04655149 ! androgen metabolic process GO:0008209 13 10 0,000 0,0187218 0,04650122 ! phospholipid efflux GO:0033700 16 10 0,000 0,0187218 0,04645106 ! hippocampus development GO:0021766 19 10 0,000 0,0187218 0,046401 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,0187218 0,04635106 ! blood vessel remodeling GO:0001974 21 10 0,000 0,0187218 0,04630122 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,0187218 0,04625148 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,0187218 0,04620186 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,0187218 0,04615234 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,0187218 0,04610292 ! pathogenesis GO:0009405 13 10 0,000 0,0187218 0,04605362 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0187218 0,04600441 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0187218 0,04595532 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,0187218 0,04590632 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,0187218 0,04585743 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,0187218 0,04580865 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,0187218 0,04575997 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,0187218 0,04571139 ! melanocyte differentiation GO:0030318 15 10 0,000 0,0187218 0,04566292 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,0187218 0,04561455 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0187218 0,04556628 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0187218 0,04551811 ! response to X-ray GO:0010165 16 10 0,000 0,0187218 0,04547004 ! B cell proliferation GO:0042100 14 10 0,000 0,0187218 0,04542208 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,0187218 0,04537422 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0187218 0,04532645 ! forebrain cell migration GO:0021885 17 10 0,000 0,0187218 0,04527879 ! lipid digestion GO:0044241 15 10 0,000 0,0187218 0,04523123 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0187218 0,04518377 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0187218 0,04513641 ! UV protection GO:0009650 14 10 0,000 0,0187218 0,04508914 ! entry into host cell GO:0030260 20 10 0,000 0,0187218 0,04504198 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,0187218 0,04499491 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0187218 0,04494794 ! negative regulation of ossification GO:0030279 19 10 0,000 0,0187218 0,04490107 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,0187218 0,0448543 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,0187218 0,04480763 ! regulation of bone resorption GO:0045124 24 10 0,000 0,0187218 0,04476105 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,0187218 0,04471457 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,0187218 0,04466819 ! regulation of organ growth GO:0046620 11 10 0,000 0,0187218 0,0446219 ! response to dsRNA GO:0043331 18 10 0,000 0,0187218 0,0445757 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,0187218 0,04452961 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0187218 0,04448361 ! embryonic axis specification GO:0000578 12 10 0,000 0,0187218 0,0444377 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,0187218 0,04439189 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0187218 0,04434617 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0187218 0,04430055 ! cranial nerve development GO:0021545 12 10 0,000 0,0187218 0,04425502 ! fucose catabolic process GO:0019317 16 10 0,000 0,0187218 0,04420958 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,0187218 0,04416424 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,0187218 0,04411899 ! protein sumoylation GO:0016925 12 10 0,000 0,0187218 0,04407383 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,0187218 0,04402876 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0187218 0,04398379 ! zymogen activation GO:0031638 14 10 0,000 0,0187218 0,04393891 ! salivary gland development GO:0007431 22 10 0,000 0,0187218 0,04389412 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0187218 0,04384942 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,0187218 0,04380481 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0187218 0,0437603 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,0187218 0,04371587 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,0187218 0,04367153 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,0187218 0,04362729 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0187218 0,04358313 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,0187218 0,04353906 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,0187218 0,04349508 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,0187218 0,04345119 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,0187218 0,04340739 ! detection of bacterium GO:0016045 10 10 0,000 0,0187218 0,04336368 ! embryonic gut development GO:0048566 11 10 0,000 0,0187218 0,04332005 ! activation of innate immune response GO:0002218 10 10 0,000 0,0187218 0,04327651 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,0187218 0,04323306 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,0187218 0,0431897 ! developmental induction GO:0031128 13 10 0,000 0,0187218 0,04314642 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,0187218 0,04310323 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,0187218 0,04306013 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,0187218 0,04301711 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,0187218 0,04297418 ! rRNA transcription GO:0009303 17 11 0,000 0,02057517 0,04718135 ! respiratory burst GO:0045730 14 11 0,000 0,02057517 0,04713436 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02057517 0,04708746 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02057517 0,04704065 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02057517 0,04699394 ! virus-host interaction GO:0019048 17 11 0,000 0,02057517 0,04694732 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02057517 0,04690079 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02057517 0,04685435 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02057517 0,04680801 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02057517 0,04676175 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02057517 0,04671559 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02057517 0,04666952 ! mating GO:0007618 14 11 0,000 0,02057517 0,04662354 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02057517 0,04657765 ! T cell proliferation GO:0042098 20 11 0,000 0,02057517 0,04653185 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02057517 0,04648614 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02057517 0,04644052 ! bone resorption GO:0045453 16 11 0,000 0,02057517 0,046395 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02057517 0,04634955 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02057517 0,0463042 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02057517 0,04625894 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02057517 0,04621376 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02057517 0,04616868 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02057517 0,04612368 ! syncytium formation GO:0006949 15 11 0,000 0,02057517 0,04607877 ! plasma membrane organization GO:0007009 18 11 0,000 0,02057517 0,04603394 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02057517 0,04598921 ! focal adhesion formation GO:0048041 24 11 0,000 0,02057517 0,04594456 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02057517 0,0459 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02057517 0,04585552 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02057517 0,04581113 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02057517 0,04576682 ! adult heart development GO:0007512 11 11 0,000 0,02057517 0,0457226 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02057517 0,04567847 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02057517 0,04563442 ! temperature homeostasis GO:0001659 16 11 0,000 0,02057517 0,04559046 ! L-glutamate transport GO:0015813 16 11 0,000 0,02057517 0,04554658 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02057517 0,04550278 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02057517 0,04545907 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02057517 0,04541545 ! stem cell development GO:0048864 29 11 0,000 0,02057517 0,0453719 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02057517 0,04532844 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02057517 0,04528507 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02057517 0,04524177 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02057517 0,04519856 ! vasoconstriction GO:0042310 15 11 0,000 0,02057517 0,04515543 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02057517 0,04511239 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02057517 0,04506942 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02057517 0,04502654 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02057517 0,04498374 ! ribosome assembly GO:0042255 13 11 0,000 0,02057517 0,04494102 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02057517 0,04489838 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02057517 0,04485582 ! chromatin silencing GO:0006342 19 11 0,000 0,02057517 0,04481335 ! nucleosome positioning GO:0016584 13 11 0,000 0,02057517 0,04477095 ! T cell homeostasis GO:0043029 20 11 0,000 0,02057517 0,04472863 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02057517 0,0446864 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02057517 0,04464424 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02057517 0,04460216 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02057517 0,04456016 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02057517 0,04451825 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02057517 0,04447641 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02057517 0,04443464 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02057517 0,04439296 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02057517 0,04435135 ! male genitalia development GO:0030539 13 11 0,000 0,02057517 0,04430983 ! cholesterol efflux GO:0033344 19 11 0,000 0,02057517 0,04426838 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02057517 0,044227 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02057517 0,04418571 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02057517 0,04414449 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02057517 0,04410335 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02057517 0,04406229 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02057517 0,0440213 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02057517 0,04398039 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02057517 0,04393955 ! lysogeny GO:0030069 18 11 0,000 0,02057517 0,04389879 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02057517 0,0438581 ! acrosome reaction GO:0007340 13 11 0,000 0,02057517 0,0438175 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02057517 0,04377696 ! lactation GO:0007595 20 12 0,000 0,02242515 0,04766899 ! reproductive cellular process GO:0048610 14 12 0,000 0,02242515 0,04762498 ! tRNA modification GO:0006400 14 12 0,000 0,02242515 0,04758104 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02242515 0,04753719 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02242515 0,04749342 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02242515 0,04744973 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02242515 0,04740611 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02242515 0,04736258 ! non-recombinational repair GO:0000726 19 12 0,000 0,02242515 0,04731913 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02242515 0,04727576 ! peroxisomal transport GO:0043574 21 12 0,000 0,02242515 0,04723246 ! cartilage condensation GO:0001502 18 12 0,000 0,02242515 0,04718925 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02242515 0,04714612 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02242515 0,04710306 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02242515 0,04706008 ! heart looping GO:0001947 15 12 0,000 0,02242515 0,04701718 ! palate development GO:0060021 15 12 0,000 0,02242515 0,04697436 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02242515 0,04693162 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02242515 0,04688896 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02242515 0,04684637 ! arginine metabolic process GO:0006525 13 12 0,000 0,02242515 0,04680386 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02242515 0,04676142 ! methionine metabolic process GO:0006555 13 12 0,000 0,02242515 0,04671907 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02242515 0,04667679 ! Golgi organization GO:0007030 18 12 0,000 0,02242515 0,04663459 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02242515 0,04659246 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02242515 0,04655041 ! monoamine transport GO:0015844 13 12 0,000 0,02242515 0,04650843 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02242515 0,04646653 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02242515 0,04642471 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02242515 0,04638296 ! L-amino acid transport GO:0015807 20 12 0,000 0,02242515 0,04634129 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02242515 0,04629969 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02242515 0,04625816 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02242515 0,04621671 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02242515 0,04617534 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02242515 0,04613404 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02242515 0,04609281 ! cerebellum development GO:0021549 13 12 0,000 0,02242515 0,04605165 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02242515 0,04601057 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02242515 0,04596956 ! histone acetylation GO:0016573 23 12 0,000 0,02242515 0,04592863 ! histone methylation GO:0016571 15 12 0,000 0,02242515 0,04588777 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02242515 0,04584698 ! gland morphogenesis GO:0022612 23 12 0,000 0,02242515 0,04580626 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02242515 0,04576562 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02242515 0,04572505 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02242515 0,04568455 ! response to gamma radiation GO:0010332 20 12 0,000 0,02242515 0,04564412 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02242515 0,04560376 ! intestinal absorption GO:0050892 19 12 0,000 0,02242515 0,04556347 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02242515 0,04552326 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02242515 0,04548311 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02242515 0,04544304 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02242515 0,04540304 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02242515 0,04536311 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02242515 0,04532324 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02242515 0,04528345 ! microspike assembly GO:0030035 23 12 0,000 0,02242515 0,04524373 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02242515 0,04520408 ! response to cold GO:0009409 14 12 0,000 0,02242515 0,04516449 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02427175 0,04884078 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02427175 0,04879809 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02427175 0,04875547 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02427175 0,04871293 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02427175 0,04867046 ! water transport GO:0006833 17 13 0,000 0,02427175 0,04862806 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02427175 0,04858574 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02427175 0,04854349 ! lipid localization GO:0010876 24 13 0,000 0,02427175 0,04850132 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02427175 0,04845921 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02427175 0,04841718 ! organelle fusion GO:0048284 28 13 0,000 0,02427175 0,04837523 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02427175 0,04833335 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02427175 0,04829153 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02427175 0,0482498 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02427175 0,04820813 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02427175 0,04816653 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02427175 0,04812501 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02427175 0,04808356 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02427175 0,04804218 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02427175 0,04800087 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02427175 0,04795963 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02427175 0,04791847 ! NAD metabolic process GO:0019674 21 13 0,000 0,02427175 0,04787737 ! exocrine system development GO:0035272 27 13 0,000 0,02427175 0,04783634 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02427175 0,04779539 ! bone mineralization GO:0030282 15 13 0,000 0,02427175 0,0477545 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02427175 0,04771369 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02427175 0,04767294 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02427175 0,04763226 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02427175 0,04759166 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02427175 0,04755112 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02427175 0,04751065 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02427175 0,04747025 ! genitalia development GO:0048806 15 13 0,000 0,02427175 0,04742992 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02427175 0,04738966 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02427175 0,04734946 ! cellular pigmentation GO:0033059 24 13 0,000 0,02427175 0,04730933 ! tissue regeneration GO:0042246 21 13 0,000 0,02427175 0,04726928 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02427175 0,04722928 ! cofactor transport GO:0051181 19 13 0,000 0,02427175 0,04718936 ! NADP metabolic process GO:0006739 18 13 0,000 0,02427175 0,04714951 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02427175 0,04710972 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02427175 0,04706999 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02427175 0,04703034 ! gas transport GO:0015669 18 13 0,000 0,02427175 0,04699075 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02427175 0,04695123 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02427175 0,04691178 ! regulation of axon extension GO:0030516 23 13 0,000 0,02427175 0,04687239 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02427175 0,04683307 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02427175 0,04679381 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02427175 0,04675462 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02427175 0,04671549 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02427175 0,04667643 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02427175 0,04663744 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02611496 0,05013723 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02611496 0,05009541 ! superoxide anion generation GO:0042554 18 14 0,000 0,02611496 0,05005366 ! neuron maturation GO:0042551 21 14 0,000 0,02611496 0,05001199 ! regulation of S phase GO:0033261 18 14 0,000 0,02611496 0,04997038 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02611496 0,04992884 ! myotube differentiation GO:0014902 21 14 0,000 0,02611496 0,04988737 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02611496 0,04984597 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02611496 0,04980464 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02611496 0,04976338 ! inositol metabolic process GO:0006020 20 14 0,000 0,02611496 0,04972218 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02611496 0,04968106 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02611496 0,04964 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02611496 0,04959901 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02611496 0,04955808 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02611496 0,04951723 ! response to cAMP GO:0051591 19 14 0,000 0,02611496 0,04947644 ! limbic system development GO:0021761 25 14 0,000 0,02611496 0,04943572 ! startle response GO:0001964 21 14 0,000 0,02611496 0,04939506 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02611496 0,04935448 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02611496 0,04931395 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02611496 0,0492735 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02611496 0,04923311 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02611496 0,04919279 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02611496 0,04915253 ! glycine metabolic process GO:0006544 22 14 0,000 0,02611496 0,04911234 ! pituitary gland development GO:0021983 23 14 0,000 0,02611496 0,04907222 ! cellular response to starvation GO:0009267 21 14 0,000 0,02611496 0,04903216 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02611496 0,04899217 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02611496 0,04895224 ! regulation of heart rate GO:0002027 23 14 0,000 0,02611496 0,04891238 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02611496 0,04887258 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02611496 0,04883284 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02611496 0,04879317 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02611496 0,04875357 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02611496 0,04871403 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02611496 0,04867455 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02611496 0,04863514 ! axon cargo transport GO:0008088 27 14 0,000 0,02611496 0,04859579 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02611496 0,0485565 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02611496 0,04851728 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02611496 0,04847812 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02611496 0,04843903 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02611496 0,0484 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02611496 0,04836103 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02611496 0,04832212 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02611496 0,04828328 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02611496 0,0482445 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02611496 0,04820578 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02611496 0,04816712 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02611496 0,04812852 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02611496 0,04808999 ! muscle maintenance GO:0046716 19 14 0,000 0,02611496 0,04805152 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02611496 0,04801311 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02611496 0,04797476 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02611496 0,04793647 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02611496 0,04789824 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02611496 0,04786008 ! cilium assembly GO:0042384 20 14 0,000 0,02611496 0,04782197 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02611496 0,04778393 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02795479 0,05110971 ! metencephalon development GO:0022037 19 15 0,000 0,02795479 0,05106911 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02795479 0,05102858 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02795479 0,05098811 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02795479 0,05094771 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02795479 0,05090737 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02795479 0,0508671 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02795479 0,05082689 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02795479 0,05078674 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02795479 0,05074666 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02795479 0,05070663 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02795479 0,05066668 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02795479 0,05062678 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02795479 0,05058695 ! adult walking behavior GO:0007628 25 15 0,000 0,02795479 0,05054718 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02795479 0,05050747 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02795479 0,05046783 ! myoblast differentiation GO:0045445 27 15 0,000 0,02795479 0,05042825 ! centrosome cycle GO:0007098 16 15 0,000 0,02795479 0,05038872 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02795479 0,05034927 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02795479 0,05030987 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02795479 0,05027053 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02795479 0,05023126 ! cerebral cortex development GO:0021987 29 15 0,000 0,02795479 0,05019205 ! response to osmotic stress GO:0006970 22 15 0,000 0,02795479 0,0501529 ! vesicle coating GO:0006901 25 15 0,000 0,02795479 0,05011381 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02795479 0,05007478 ! DNA integration GO:0015074 22 15 0,000 0,02795479 0,05003581 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02795479 0,0499969 ! peptide secretion GO:0002790 27 15 0,000 0,02795479 0,04995805 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02795479 0,04991926 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02795479 0,04988054 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02795479 0,04984187 ! neuron recognition GO:0008038 22 15 0,000 0,02795479 0,04980326 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02795479 0,04976472 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02795479 0,04972623 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02795479 0,0496878 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02795479 0,04964943 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02795479 0,04961112 ! biomineral formation GO:0031214 18 15 0,000 0,02795479 0,04957287 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02795479 0,04953468 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02795479 0,04949655 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02795479 0,04945847 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02795479 0,04942046 ! organic cation transport GO:0015695 19 15 0,000 0,02795479 0,0493825 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02795479 0,0493446 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02795479 0,04930676 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02795479 0,04926898 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02795479 0,04923125 ! defense response to virus GO:0051607 27 15 0,000 0,02795479 0,04919358 ! peptide hormone processing GO:0016486 19 15 0,000 0,02795479 0,04915597 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02795479 0,04911842 ! protein secretion GO:0009306 27 16 0,000 0,02979125 0,05230525 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02979125 0,05226535 ! hormone secretion GO:0046879 25 16 0,000 0,02979125 0,05222552 ! bone remodeling GO:0046849 24 16 0,000 0,02979125 0,05218574 ! endothelial cell migration GO:0043542 22 16 0,000 0,02979125 0,05214603 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02979125 0,05210637 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02979125 0,05206678 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02979125 0,05202724 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02979125 0,05198777 ! glial cell development GO:0021782 24 16 0,000 0,02979125 0,05194835 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02979125 0,051909 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02979125 0,0518697 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02979125 0,05183047 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02979125 0,05179129 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02979125 0,05175217 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02979125 0,05171311 ! regulation of protein binding GO:0043393 27 16 0,000 0,02979125 0,05167412 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02979125 0,05163517 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02979125 0,05159629 ! protein export from nucleus GO:0006611 24 16 0,000 0,02979125 0,05155747 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02979125 0,0515187 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02979125 0,05148 ! DNA replication initiation GO:0006270 25 16 0,000 0,02979125 0,05144135 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02979125 0,05140276 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02979125 0,05136423 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02979125 0,05132575 ! diencephalon development GO:0021536 25 16 0,000 0,02979125 0,05128733 ! oogenesis GO:0048477 23 16 0,000 0,02979125 0,05124897 ! neural crest cell migration GO:0001755 24 16 0,000 0,02979125 0,05121067 ! G1 phase GO:0051318 27 16 0,000 0,02979125 0,05117242 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02979125 0,05113424 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02979125 0,05109611 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02979125 0,05105803 ! steroid catabolic process GO:0006706 22 16 0,000 0,02979125 0,05102001 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02979125 0,05098205 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02979125 0,05094415 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02979125 0,0509063 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02979125 0,05086851 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02979125 0,05083077 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02979125 0,05079309 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02979125 0,05075546 ! nerve development GO:0021675 18 16 0,000 0,02979125 0,0507179 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02979125 0,05068038 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02979125 0,05064292 ! negative regulation of translation GO:0017148 22 16 0,000 0,02979125 0,05060552 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03162435 0,05367971 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03162435 0,05364012 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03162435 0,05360059 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03162435 0,05356112 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03162435 0,05352171 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03162435 0,05348235 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03162435 0,05344306 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03162435 0,05340382 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03162435 0,05336464 ! signal complex assembly GO:0007172 29 17 0,000 0,03162435 0,05332551 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03162435 0,05328645 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03162435 0,05324744 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03162435 0,05320849 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03162435 0,05316959 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03162435 0,05313075 ! memory GO:0007613 25 17 0,000 0,03162435 0,05309197 ! keratinization GO:0031424 17 17 0,000 0,03162435 0,05305325 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03162435 0,05301458 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03162435 0,05297597 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03162435 0,05293741 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,03162435 0,05289891 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03162435 0,05286047 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03162435 0,05282208 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03162435 0,05278375 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03162435 0,05274547 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03162435 0,05270725 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03162435 0,05266908 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03162435 0,05263097 ! heme metabolic process GO:0042168 27 17 0,000 0,03162435 0,05259292 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03162435 0,05255491 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03162435 0,05251697 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03162435 0,05247908 ! body fluid secretion GO:0007589 27 17 0,000 0,03162435 0,05244124 ! stem cell differentiation GO:0048863 36 17 0,000 0,03162435 0,05240346 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03162435 0,05236573 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03162435 0,05232806 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03162435 0,05229044 ! sensory perception of pain GO:0019233 23 17 0,000 0,03162435 0,05225288 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03162435 0,05221536 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03162435 0,05217791 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03162435 0,0521405 ! synaptogenesis GO:0007416 24 17 0,000 0,03162435 0,05210315 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03162435 0,05206586 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03162435 0,05202861 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03162435 0,05199142 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03162435 0,05195429 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03162435 0,0519172 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03162435 0,05188017 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03162435 0,05184319 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03162435 0,05180627 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03162435 0,0517694 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03345409 0,05472575 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03345409 0,05468685 ! positive regulation of translation GO:0045727 28 18 0,000 0,03345409 0,05464801 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03345409 0,05460923 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03345409 0,0545705 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03345409 0,05453182 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03345409 0,0544932 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03345409 0,05445464 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03345409 0,05441613 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03345409 0,05437767 ! axis specification GO:0009798 26 18 0,000 0,03345409 0,05433927 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03345409 0,05430092 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03345409 0,05426263 ! pancreas development GO:0031016 26 18 0,000 0,03345409 0,05422439 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03345409 0,0541862 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03345409 0,05414807 ! response to retinoic acid GO:0032526 25 18 0,000 0,03345409 0,05410999 ! pigmentation during development GO:0048066 31 18 0,000 0,03345409 0,05407196 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03345409 0,05403399 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03345409 0,05399607 ! fucose metabolic process GO:0006004 26 18 0,000 0,03345409 0,05395821 ! response to fungus GO:0009620 19 18 0,000 0,03345409 0,05392039 ! peptide cross-linking GO:0018149 31 18 0,000 0,03345409 0,05388263 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03345409 0,05384493 ! heart process GO:0003015 27 18 0,000 0,03345409 0,05380727 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03345409 0,05376967 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03345409 0,05373212 ! visual learning GO:0008542 35 18 0,000 0,03345409 0,05369463 ! somitogenesis GO:0001756 24 18 0,000 0,03345409 0,05365718 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03345409 0,05361979 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03345409 0,05358245 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03345409 0,05354517 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03345409 0,05350793 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03345409 0,05347075 ! vitamin transport GO:0051180 24 18 0,000 0,03345409 0,05343361 ! hormone transport GO:0009914 27 18 0,000 0,03345409 0,05339653 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03345409 0,0533595 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03345409 0,05332252 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03345409 0,0532856 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03345409 0,05324872 ! cell-cell recognition GO:0009988 20 18 0,000 0,03345409 0,0532119 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03345409 0,05317512 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03345409 0,0531384 ! regulation of glucose import GO:0046324 21 18 0,000 0,03345409 0,05310173 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03345409 0,05306511 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03345409 0,05302853 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03345409 0,05299201 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03345409 0,05295554 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03528047 0,05580818 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03528047 0,05576982 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03528047 0,05573152 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03528047 0,05569327 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03528047 0,05565507 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03528047 0,05561692 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03528047 0,05557883 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03528047 0,05554079 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03528047 0,0555028 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03528047 0,05546486 ! regeneration GO:0031099 32 19 0,000 0,03528047 0,05542698 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03528047 0,05538914 ! response to alkaloid GO:0043279 32 19 0,000 0,03528047 0,05535136 ! sensory perception of taste GO:0050909 23 19 0,000 0,03528047 0,05531363 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03528047 0,05527595 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03528047 0,05523832 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03528047 0,05520074 ! peroxisome organization GO:0007031 29 19 0,000 0,03528047 0,05516322 ! digestive system process GO:0022600 30 19 0,000 0,03528047 0,05512574 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03528047 0,05508832 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03528047 0,05505094 ! response to vitamin A GO:0033189 26 19 0,000 0,03528047 0,05501362 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03528047 0,05497635 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03528047 0,05493913 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03528047 0,05490196 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03528047 0,05486484 ! response to starvation GO:0042594 30 19 0,000 0,03528047 0,05482776 ! sex determination GO:0007530 29 19 0,000 0,03528047 0,05479074 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03528047 0,05475377 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03528047 0,05471685 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03528047 0,05467998 ! cytolysis GO:0019835 20 19 0,000 0,03528047 0,05464316 ! renal system process GO:0003014 35 19 0,000 0,03528047 0,05460639 ! vasodilation GO:0042311 33 19 0,000 0,03528047 0,05456966 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03528047 0,05453299 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03528047 0,05449637 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03528047 0,05445979 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03528047 0,05442327 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03528047 0,05438679 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03528047 0,05435036 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03528047 0,05431398 ! sarcomere organization GO:0045214 23 19 0,000 0,03528047 0,05427765 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03528047 0,05424137 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03528047 0,05420514 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03528047 0,05416895 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03528047 0,05413282 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03528047 0,05409673 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03528047 0,05406069 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03528047 0,05402469 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03528047 0,05398875 ! protein stabilization GO:0050821 26 19 0,000 0,03528047 0,05395285 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03710351 0,05670305 ! iron ion transport GO:0006826 37 20 0,000 0,03710351 0,05666539 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03710351 0,05662779 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03710351 0,05659024 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03710351 0,05655274 ! response to vitamin GO:0033273 29 20 0,000 0,03710351 0,05651529 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03710351 0,05647788 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03710351 0,05644053 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03710351 0,05640323 ! spinal cord development GO:0021510 31 20 0,000 0,03710351 0,05636597 ! response to ethanol GO:0045471 37 20 0,000 0,03710351 0,05632877 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03710351 0,05629161 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03710351 0,0562545 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03710351 0,05621745 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03710351 0,05618044 ! chromosome condensation GO:0030261 31 20 0,000 0,03710351 0,05614348 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03710351 0,05610656 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03710351 0,0560697 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03710351 0,05603288 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03710351 0,05599612 ! pallium development GO:0021543 38 20 0,000 0,03710351 0,0559594 ! DNA modification GO:0006304 28 20 0,000 0,03710351 0,05592273 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03710351 0,05588611 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03710351 0,05584953 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03710351 0,055813 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03710351 0,05577652 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03710351 0,05574009 ! collagen catabolic process GO:0030574 25 20 0,000 0,03710351 0,05570371 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03710351 0,05566737 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03710351 0,05563108 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03710351 0,05559484 ! actin filament-based movement GO:0030048 34 20 0,000 0,03710351 0,05555865 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03892321 0,05824554 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03892321 0,05820767 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,03892321 0,05816984 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03892321 0,05813207 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03892321 0,05809435 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03892321 0,05805667 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03892321 0,05801905 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03892321 0,05798147 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03892321 0,05794394 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03892321 0,05790646 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03892321 0,05786903 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03892321 0,05783165 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03892321 0,05779431 ! vesicle docking GO:0048278 27 21 0,000 0,03892321 0,05775703 ! phototransduction GO:0007602 25 21 0,000 0,03892321 0,05771979 ! dendrite development GO:0016358 35 21 0,000 0,03892321 0,0576826 ! visual behavior GO:0007632 39 21 0,000 0,03892321 0,05764545 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03892321 0,05760836 ! ovarian follicle development GO:0001541 30 21 0,000 0,03892321 0,05757131 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03892321 0,05753431 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03892321 0,05749736 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03892321 0,05746046 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03892321 0,0574236 ! cell aging GO:0007569 32 21 0,000 0,03892321 0,05738679 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03892321 0,05735003 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03892321 0,05731331 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03892321 0,05727664 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03892321 0,05724002 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03892321 0,05720344 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03892321 0,05716692 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03892321 0,05713043 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03892321 0,057094 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03892321 0,05705761 ! fatty acid transport GO:0015908 30 21 0,000 0,03892321 0,05702127 ! immunoglobulin production GO:0002377 33 21 0,000 0,03892321 0,05698497 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03892321 0,05694872 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03892321 0,05691252 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03892321 0,05687636 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03892321 0,05684025 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03892321 0,05680418 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03892321 0,05676816 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03892321 0,05673219 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03892321 0,05669626 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03892321 0,05666037 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03892321 0,05662454 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03892321 0,05658874 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03892321 0,05655299 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03892321 0,05651729 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04073958 0,05911737 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04073958 0,05908009 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04073958 0,05904287 ! viral genome replication GO:0019079 29 22 0,000 0,04073958 0,05900569 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04073958 0,05896855 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04073958 0,05893146 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04073958 0,05889442 ! molting cycle process GO:0022404 40 22 0,000 0,04073958 0,05885743 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04073958 0,05882048 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04073958 0,05878358 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04073958 0,05874673 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04073958 0,05870992 ! vasculogenesis GO:0001570 33 22 0,000 0,04073958 0,05867315 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04073958 0,05863644 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04073958 0,05859977 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04073958 0,05856314 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04073958 0,05852656 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04073958 0,05849003 ! lysosome organization GO:0007040 37 22 0,000 0,04073958 0,05845354 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04073958 0,0584171 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04073958 0,0583807 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04073958 0,05834435 ! regulation of behavior GO:0050795 38 22 0,000 0,04073958 0,05830805 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04073958 0,05827178 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04073958 0,05823557 ! membrane depolarization GO:0051899 35 22 0,000 0,04073958 0,0581994 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04073958 0,05816327 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04073958 0,05812719 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,04073958 0,05809115 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04073958 0,05805516 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04073958 0,05801921 ! blastocyst development GO:0001824 37 22 0,000 0,04073958 0,05798331 ! neural tube closure GO:0001843 33 22 0,000 0,04073958 0,05794745 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04073958 0,05791164 ! protein tetramerization GO:0051262 39 22 0,000 0,04073958 0,05787587 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04255261 0,0604142 ! neuron fate commitment GO:0048663 32 23 0,000 0,04255261 0,06037693 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04255261 0,06033971 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04255261 0,06030253 ! myelination GO:0042552 35 23 0,000 0,04255261 0,0602654 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04255261 0,06022831 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04255261 0,06019127 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04255261 0,06015428 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04255261 0,06011733 ! vesicle targeting GO:0006903 32 23 0,000 0,04255261 0,06008042 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04255261 0,06004356 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04255261 0,06000675 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04255261 0,05996998 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04255261 0,05993326 ! interaction with host GO:0051701 37 23 0,000 0,04255261 0,05989658 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04255261 0,05985994 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04255261 0,05982336 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04255261 0,05978681 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04255261 0,05975031 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04255261 0,05971386 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04255261 0,05967744 ! cell fate determination GO:0001709 45 23 0,000 0,04255261 0,05964108 ! pentose metabolic process GO:0019321 31 23 0,000 0,04255261 0,05960476 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04255261 0,05956848 ! spermatid development GO:0007286 33 23 0,000 0,04255261 0,05953224 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04255261 0,05949605 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04255261 0,05945991 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04255261 0,05942381 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04255261 0,05938775 ! telomere organization GO:0032200 32 23 0,000 0,04255261 0,05935173 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04255261 0,05931576 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04255261 0,05927984 ! regulation of amine transport GO:0051952 38 23 0,000 0,04255261 0,05924395 ! liver development GO:0001889 40 23 0,000 0,04255261 0,05920811 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04436232 0,06168884 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04436232 0,06165157 ! initiation of viral infection GO:0019059 42 24 0,000 0,04436232 0,06161434 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04436232 0,06157716 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04436232 0,06154002 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04436232 0,06150292 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04436232 0,06146587 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04436232 0,06142887 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04436232 0,06139191 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04436232 0,06135499 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04436232 0,06131812 ! vacuole organization GO:0007033 39 24 0,000 0,04436232 0,06128129 ! receptor metabolic process GO:0043112 37 24 0,000 0,04436232 0,06124451 ! neural crest cell development GO:0014032 39 24 0,000 0,04436232 0,06120777 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04436232 0,06117107 ! primary neural tube formation GO:0014020 35 24 0,000 0,04436232 0,06113442 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04436232 0,06109781 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04436232 0,06106125 ! base-excision repair GO:0006284 31 24 0,000 0,04436232 0,06102473 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04436232 0,06098825 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04436232 0,06095182 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04436232 0,06091543 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04436232 0,06087909 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04436232 0,06084278 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04436232 0,06080652 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04436232 0,06077031 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04616872 0,06320718 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04616872 0,06316958 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04616872 0,06313202 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04616872 0,06309451 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04616872 0,06305704 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04616872 0,06301962 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04616872 0,06298224 ! peptide transport GO:0015833 43 25 0,000 0,04616872 0,06294491 ! male gonad development GO:0008584 33 25 0,000 0,04616872 0,06290762 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04616872 0,06287037 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04616872 0,06283317 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04616872 0,06279601 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04616872 0,0627589 ! phospholipid transport GO:0015914 35 25 0,000 0,04616872 0,06272183 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04616872 0,0626848 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04616872 0,06264782 ! detection of light stimulus GO:0009583 30 25 0,000 0,04616872 0,06261088 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04616872 0,06257399 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04616872 0,06253714 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04616872 0,06250033 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04616872 0,06246356 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,0479718 0,06486487 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,0479718 0,06482676 ! translational initiation GO:0006413 43 26 0,000 0,0479718 0,0647887 ! regulation of pH GO:0006885 36 26 0,000 0,0479718 0,06475067 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,0479718 0,0647127 ! circadian rhythm GO:0007623 42 26 0,000 0,0479718 0,06467476 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,0479718 0,06463688 ! post-embryonic development GO:0009791 42 26 0,000 0,0479718 0,06459903 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,0479718 0,06456123 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,0479718 0,06452348 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,0479718 0,06448577 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,0479718 0,0644481 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,0479718 0,06441048 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,0479718 0,0643729 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,0479718 0,06433536 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,0479718 0,06429787 ! regulation of coagulation GO:0050818 39 26 0,000 0,0479718 0,06426042 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04977158 0,0666325 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04977158 0,06659374 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04977158 0,06655502 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04977158 0,06651635 ! membrane docking GO:0022406 39 27 0,000 0,04977158 0,06647772 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04977158 0,06643914 ! catechol metabolic process GO:0009712 43 27 0,000 0,04977158 0,0664006 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04977158 0,06636211 ! acute-phase response GO:0006953 42 27 0,000 0,04977158 0,06632366 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04977158 0,06628526 ! myofibril assembly GO:0030239 36 27 0,000 0,04977158 0,0662469 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04977158 0,06620858 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04977158 0,06617031 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04977158 0,06613208 ! natural killer cell activation GO:0030101 35 27 0,000 0,04977158 0,0660939 ! lipid oxidation GO:0034440 38 27 0,000 0,04977158 0,06605576 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04977158 0,06601767 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04977158 0,06597962 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04977158 0,06594161 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04977158 0,06590365 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04977158 0,06586573 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04977158 0,06582785 ! gene silencing GO:0016458 41 27 0,000 0,04977158 0,06579002 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05156806 0,06812553 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05156806 0,06808642 ! phenol metabolic process GO:0018958 44 28 0,000 0,05156806 0,06804735 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05156806 0,06800834 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05156806 0,06796936 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05156806 0,06793044 ! cell junction assembly GO:0034329 56 28 0,000 0,05156806 0,06789155 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05156806 0,06785271 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05156806 0,06781392 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05156806 0,06777517 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05156806 0,06773646 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05156806 0,0676978 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05156806 0,06765918 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05156806 0,0676206 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05156806 0,06758207 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05156806 0,06754359 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05156806 0,06750514 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05156806 0,06746675 ! mesoderm formation GO:0001707 46 28 0,000 0,05156806 0,06742839 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05156806 0,06739008 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,05156806 0,06735181 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05156806 0,06731359 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05156806 0,06727541 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05156806 0,06723727 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05156806 0,06719917 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05156806 0,06716112 ! neural tube formation GO:0001841 41 28 0,000 0,05156806 0,06712311 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05156806 0,06708515 ! placenta development GO:0001890 37 28 0,000 0,05156806 0,06704722 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05336125 0,06933947 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05336125 0,06930032 ! ovulation cycle process GO:0022602 41 29 0,000 0,05336125 0,06926121 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05336125 0,06922215 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05336125 0,06918313 ! mismatch repair GO:0006298 34 29 0,000 0,05336125 0,06914415 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05336125 0,06910522 ! muscle cell development GO:0055001 38 29 0,000 0,05336125 0,06906633 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05336125 0,06902748 ! telencephalon development GO:0021537 52 29 0,000 0,05336125 0,06898868 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05336125 0,06894992 ! tissue homeostasis GO:0001894 42 29 0,000 0,05336125 0,06891121 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05515114 0,07118273 ! collagen metabolic process GO:0032963 40 30 0,000 0,05515114 0,07114281 ! organic anion transport GO:0015711 51 30 0,000 0,05515114 0,07110293 ! cholesterol transport GO:0030301 46 30 0,000 0,05515114 0,0710631 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05515114 0,07102331 ! spliceosome assembly GO:0000245 49 30 0,000 0,05515114 0,07098356 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05515114 0,07094386 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05515114 0,07090421 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05515114 0,0708646 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05515114 0,07082503 ! ovulation cycle GO:0042698 43 30 0,000 0,05515114 0,07078551 ! hindbrain development GO:0030902 45 30 0,000 0,05515114 0,07074603 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05515114 0,07070659 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05515114 0,0706672 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05515114 0,07062786 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05515114 0,07058855 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05515114 0,07054929 ! response to heat GO:0009408 41 30 0,000 0,05515114 0,07051008 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05515114 0,07047091 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05515114 0,07043178 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05693776 0,07267305 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05693776 0,07263275 ! mammary gland development GO:0030879 57 31 0,000 0,05693776 0,07259249 ! glial cell differentiation GO:0010001 55 31 0,000 0,05693776 0,07255227 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05693776 0,0725121 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05693776 0,07247197 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05693776 0,07243188 ! odontogenesis GO:0042476 50 31 0,000 0,05693776 0,07239184 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05693776 0,07235185 ! segmentation GO:0035282 41 31 0,000 0,05693776 0,0723119 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05693776 0,07227199 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05693776 0,07223213 ! metanephros development GO:0001656 58 31 0,000 0,05693776 0,07219231 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05693776 0,07215253 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05693776 0,0721128 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05693776 0,07207311 ! cell fate specification GO:0001708 37 31 0,000 0,05693776 0,07203347 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05693776 0,07199387 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05693776 0,07195431 ! RNA modification GO:0009451 40 31 0,000 0,05693776 0,0719148 ! regulation of muscle development GO:0048634 48 32 0,000 0,0587211 0,07412652 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0587211 0,07408586 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0587211 0,07404524 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,0587211 0,07400467 ! meiosis I GO:0007127 52 32 0,000 0,0587211 0,07396414 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,0587211 0,07392366 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,0587211 0,07388322 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,0587211 0,07384282 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,0587211 0,07380247 ! peripheral nervous system development GO:0007422 53 32 0,000 0,0587211 0,07376217 ! regulation of protein stability GO:0031647 48 32 0,000 0,0587211 0,0737219 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,0587211 0,07368168 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0587211 0,07364151 ! cytokine production GO:0001816 44 32 0,000 0,0587211 0,07360138 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,0587211 0,07356129 ! vesicle localization GO:0051648 47 32 0,000 0,0587211 0,07352124 ! RNA export from nucleus GO:0006405 44 33 0,000 0,06050117 0,07570875 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06050117 0,07566758 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06050117 0,07562646 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06050117 0,07558538 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06050117 0,07554435 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06050117 0,07550336 ! ear morphogenesis GO:0042471 42 33 0,000 0,06050117 0,07546241 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06050117 0,07542151 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06050117 0,07538065 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06050117 0,07533984 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06050117 0,07529907 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06050117 0,07525835 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06050117 0,07521767 ! female gonad development GO:0008585 49 33 0,000 0,06050117 0,07517703 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06050117 0,07513644 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06050117 0,07509589 ! lipid homeostasis GO:0055088 55 33 0,000 0,06050117 0,07505539 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06050117 0,07501492 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06050117 0,07497451 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06050117 0,07493413 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,06050117 0,0748938 ! cytokinesis GO:0000910 52 33 0,000 0,06050117 0,07485351 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06050117 0,07481327 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06227797 0,07696901 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06227797 0,07692768 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06227797 0,07688638 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06227797 0,07684514 ! feeding behavior GO:0007631 45 34 0,000 0,06227797 0,07680393 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06227797 0,07676277 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06227797 0,07672166 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06227797 0,07668059 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06227797 0,07663956 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06227797 0,07659857 ! neuron migration GO:0001764 46 34 0,000 0,06227797 0,07655763 ! female gamete generation GO:0007292 43 34 0,000 0,06227797 0,07651674 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06227797 0,07647589 ! aerobic respiration GO:0009060 47 34 0,000 0,06227797 0,07643508 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06227797 0,07639431 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,06227797 0,07635359 ! embryonic organ development GO:0048568 45 34 0,000 0,06227797 0,07631291 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06227797 0,07627228 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06405152 0,0784026 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06405152 0,0783609 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06405152 0,07831924 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06405152 0,07827762 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06405152 0,07823605 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06405152 0,07819453 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06405152 0,07815304 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06405152 0,07811161 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06405152 0,07807021 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06405152 0,07802886 ! pigment metabolic process GO:0042440 61 35 0,000 0,06405152 0,07798755 ! protein homooligomerization GO:0051260 52 35 0,000 0,06405152 0,07794629 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06582181 0,08005826 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06582181 0,08001594 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06582181 0,07997367 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06582181 0,07993145 ! negative regulation of binding GO:0051100 58 36 0,000 0,06582181 0,07988927 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06582181 0,07984713 ! tissue remodeling GO:0048771 62 36 0,000 0,06582181 0,07980504 ! neural tube development GO:0021915 50 36 0,000 0,06582181 0,07976299 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06582181 0,07972099 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06582181 0,07967903 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06582181 0,07963712 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06582181 0,07959525 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06758886 0,08168911 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06758886 0,0816462 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06758886 0,08160334 ! learning GO:0007612 67 37 0,000 0,06758886 0,08156053 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06758886 0,08151776 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06758886 0,08147504 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06758886 0,08143236 ! amino acid activation GO:0043038 52 37 0,000 0,06758886 0,08138972 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06758886 0,08134713 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06935266 0,08342632 ! gliogenesis GO:0042063 71 38 0,000 0,06935266 0,08338271 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,06935266 0,08333914 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06935266 0,08329562 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06935266 0,08325215 ! phagocytosis GO:0006909 60 38 0,000 0,06935266 0,08320872 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06935266 0,08316534 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06935266 0,083122 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06935266 0,08307871 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,07111323 0,08514338 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,07111323 0,08509908 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,07111323 0,08505482 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,07111323 0,08501062 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,07111323 0,08496646 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,07111323 0,08492234 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,07111323 0,08487827 ! male sex differentiation GO:0046661 53 39 0,000 0,07111323 0,08483425 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,07111323 0,08479027 ! chromatin remodeling GO:0006338 68 39 0,000 0,07111323 0,08474634 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,07111323 0,08470245 ! JNK cascade GO:0007254 54 39 0,000 0,07111323 0,08465861 ! developmental growth GO:0048589 62 39 0,000 0,07111323 0,08461481 ! cell growth GO:0016049 61 39 0,000 0,07111323 0,08457106 ! synapse organization GO:0050808 55 39 0,000 0,07111323 0,08452735 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07287057 0,08657144 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07287057 0,08652675 ! regulation of tube size GO:0035150 60 40 0,000 0,07287057 0,0864821 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07287057 0,0864375 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07287057 0,08639294 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07287057 0,08634843 ! peptide metabolic process GO:0006518 56 40 0,000 0,07287057 0,08630397 ! inner ear development GO:0048839 57 40 0,000 0,07287057 0,08625955 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07287057 0,08621518 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07287057 0,08617085 ! double-strand break repair GO:0006302 67 40 0,000 0,07287057 0,08612657 ! B cell differentiation GO:0030183 62 40 0,000 0,07287057 0,08608234 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07287057 0,08603814 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07287057 0,085994 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07287057 0,0859499 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07462468 0,08797374 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07462468 0,08792867 ! glucose transport GO:0015758 52 41 0,000 0,07462468 0,08788365 ! endosome transport GO:0016197 71 41 0,000 0,07462468 0,08783867 ! striated muscle contraction GO:0006941 62 41 0,000 0,07462468 0,08779374 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07462468 0,08774886 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07462468 0,08770402 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07462468 0,08765923 ! biopolymer methylation GO:0043414 62 41 0,000 0,07462468 0,08761448 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07462468 0,08756978 ! mitochondrial transport GO:0006839 60 42 0,000 0,07637558 0,0895787 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,07637558 0,08953304 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,07637558 0,08948743 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,07637558 0,08944187 ! cellular component disassembly GO:0022411 64 42 0,000 0,07637558 0,08939635 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,07637558 0,08935088 ! hexose transport GO:0008645 54 42 0,000 0,07637558 0,08930546 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,07637558 0,08926008 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,07637558 0,08921474 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,07637558 0,08916946 ! excretion GO:0007588 63 42 0,000 0,07637558 0,08912422 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,07637558 0,08907902 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,07637558 0,08903387 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,07637558 0,08898877 ! regulation of cell shape GO:0008360 78 42 0,000 0,07637558 0,08894371 ! positive regulation of binding GO:0051099 59 43 0,000 0,07812326 0,09093295 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,07812326 0,09088695 ! leukocyte migration GO:0050900 60 43 0,000 0,07812326 0,090841 ! neuromuscular process GO:0050905 79 43 0,000 0,07812326 0,0907951 ! activation of caspase activity GO:0006919 65 43 0,000 0,07812326 0,09074925 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07812326 0,09070344 ! tRNA processing GO:0008033 49 43 0,000 0,07812326 0,09065767 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07812326 0,09061195 ! response to insulin stimulus GO:0032868 63 43 0,000 0,07812326 0,09056628 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,07812326 0,09052066 ! methylation GO:0032259 64 43 0,000 0,07812326 0,09047508 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07986774 0,09244882 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07986774 0,09240231 ! glycolysis GO:0006096 53 44 0,000 0,07986774 0,09235586 ! regulation of action potential GO:0001508 71 44 0,000 0,07986774 0,09230945 ! regulation of ion transport GO:0043269 57 44 0,000 0,07986774 0,09226308 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07986774 0,09221677 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07986774 0,0921705 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07986774 0,09212427 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07986774 0,0920781 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07986774 0,09203196 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07986774 0,09198588 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07986774 0,09193984 ! RNA catabolic process GO:0006401 64 45 0,000 0,08160902 0,09389732 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08160902 0,09385037 ! regulation of translational initiation GO:0006446 64 45 0,000 0,08160902 0,09380347 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08160902 0,09375661 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08160902 0,0937098 ! cell recognition GO:0008037 58 45 0,000 0,08160902 0,09366304 ! cell maturation GO:0048469 60 45 0,000 0,08160902 0,09361633 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,08160902 0,09356966 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,0833471 0,09551486 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,0833471 0,09546729 ! cell redox homeostasis GO:0045454 63 46 0,000 0,0833471 0,09541977 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,0833471 0,0953723 ! regulation of ossification GO:0030278 71 46 0,000 0,0833471 0,09532487 ! histone modification GO:0016570 68 46 0,000 0,0833471 0,0952775 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,0833471 0,09523016 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08508199 0,09716413 ! viral infectious cycle GO:0019058 71 47 0,000 0,08508199 0,09711591 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,08508199 0,09706774 ! endocrine system development GO:0035270 83 47 0,000 0,08508199 0,09701962 ! covalent chromatin modification GO:0016569 75 47 0,000 0,08508199 0,09697154 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08508199 0,09692351 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08508199 0,09687553 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,08508199 0,09682759 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08508199 0,09677971 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,08508199 0,09673187 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,08508199 0,09668407 ! chloride transport GO:0006821 67 48 0,000 0,08681369 0,09860321 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,08681369 0,09855454 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,08681369 0,09850592 ! response to temperature stimulus GO:0009266 62 48 0,000 0,08681369 0,09845734 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,08681369 0,09840882 ! gastrulation GO:0007369 73 48 0,000 0,08681369 0,09836034 ! heart morphogenesis GO:0003007 65 48 0,000 0,08681369 0,09831191 ! regulation of DNA replication GO:0006275 75 48 0,000 0,08681369 0,09826353 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,08681369 0,0982152 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,08681369 0,09816691 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,08681369 0,09811867 ! regulation of endocytosis GO:0030100 63 48 0,000 0,08681369 0,09807048 ! nuclear export GO:0051168 69 48 0,000 0,08681369 0,09802233 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,08681369 0,09797424 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,08681369 0,09792619 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08854222 0,09982701 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08854222 0,0997781 ! sensory perception of smell GO:0007608 61 49 0,000 0,08854222 0,09972924 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08854222 0,09968042 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08854222 0,09963166 ! RNA elongation GO:0006354 62 49 0,000 0,08854222 0,09958294 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,08854222 0,09953426 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08854222 0,09948564 ! germ cell development GO:0007281 68 49 0,000 0,08854222 0,09943706 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08854222 0,09938853 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08854222 0,09934005 ! cartilage development GO:0051216 70 49 0,000 0,08854222 0,09929162 ! maintenance of location GO:0051235 84 49 0,000 0,08854222 0,09924323 ! regulation of actin filament length GO:0030832 72 50 0,000 0,09026757 0,10112782 ! ear development GO:0043583 72 50 0,000 0,09026757 0,10107859 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,09026757 0,1010294 ! membrane fusion GO:0006944 80 50 0,000 0,09026757 0,10098026 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,09026757 0,10093117 ! lipid modification GO:0030258 73 50 0,000 0,09026757 0,10088213 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09026757 0,10083313 ! proton transport GO:0015992 75 50 0,000 0,09026757 0,10078418 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09026757 0,10073528 ! positive regulation of secretion GO:0051047 71 51 0,000 0,09198976 0,1026074 ! hydrogen transport GO:0006818 77 51 0,000 0,09198976 0,10255766 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,09198976 0,10250797 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,09198976 0,10245833 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,09198976 0,10240874 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,09198976 0,10235919 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,09198976 0,1023097 ! adult behavior GO:0030534 80 51 0,000 0,09198976 0,10226025 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,09198976 0,10221085 ! transition metal ion transport GO:0000041 74 52 0,000 0,09370879 0,1040706 ! regulation of cellular component size GO:0032535 74 52 0,000 0,09370879 0,10402037 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,09370879 0,10397019 ! aging GO:0007568 79 52 0,000 0,09370879 0,10392006 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09370879 0,10386998 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09370879 0,10381995 ! establishment of organelle localization GO:0051656 85 52 0,000 0,09370879 0,10376996 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,09542466 0,10561921 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,09542466 0,1055684 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,09542466 0,10551765 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,09542466 0,10546694 ! kidney development GO:0001822 90 53 0,000 0,09542466 0,10541629 ! single fertilization GO:0007338 59 53 0,000 0,09542466 0,10536568 ! cell projection assembly GO:0030031 76 53 0,000 0,09542466 0,10531512 ! amino acid transport GO:0006865 84 54 0,000 0,09713738 0,10715394 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,09713738 0,10710257 ! regulation of mitosis GO:0007088 84 54 0,000 0,09713738 0,10705125 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,09713738 0,10699998 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,09713738 0,10694876 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,09713738 0,10689759 ! DNA catabolic process GO:0006308 67 54 0,000 0,09713738 0,10684647 ! detection of external stimulus GO:0009581 66 54 0,000 0,09713738 0,10679539 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,09713738 0,10674437 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,09713738 0,10669339 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,09713738 0,10664247 ! exocytosis GO:0006887 74 55 0,000 0,09884695 0,10846755 ! mesoderm development GO:0007498 76 55 0,000 0,09884695 0,10841583 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09884695 0,10836415 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09884695 0,10831252 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,10055339 0,1101299 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10055339 0,11007748 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,10055339 0,11002511 ! carbohydrate transport GO:0008643 74 57 0,000 0,10225669 0,11183566 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,10225669 0,1117825 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,10225669 0,1117294 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,10225669 0,11167635 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,10225669 0,11162334 ! camera-type eye development GO:0043010 88 57 0,000 0,10225669 0,11157039 ! secondary metabolic process GO:0019748 84 57 0,000 0,10225669 0,11151749 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,10225669 0,11146464 ! developmental maturation GO:0021700 75 57 0,000 0,10225669 0,11141183 ! gonad development GO:0008406 79 57 0,000 0,10225669 0,11135908 ! viral reproductive process GO:0022415 87 58 0,000 0,10395686 0,11315702 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10395686 0,11310349 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,10395686 0,11305002 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10395686 0,11299659 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,10565391 0,11478696 ! activation of MAPK activity GO:0000187 84 59 0,000 0,10565391 0,11473277 ! lung development GO:0030324 94 59 0,000 0,10565391 0,11467862 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,10565391 0,11462453 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,10565391 0,11457049 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,10734785 0,11635252 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,10734785 0,11629772 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,10734785 0,11624296 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,10734785 0,11618826 ! regulation of heart contraction GO:0008016 91 60 0,000 0,10734785 0,11613361 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,10734785 0,11607901 ! fertilization GO:0009566 68 60 0,000 0,10734785 0,11602446 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,10734785 0,11596996 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,10903867 0,11774129 ! meiosis GO:0007126 96 61 0,000 0,10903867 0,11768604 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,10903867 0,11763084 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,10903867 0,11757569 ! urogenital system development GO:0001655 101 61 0,000 0,10903867 0,11752059 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,10903867 0,11746555 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,10903867 0,11741055 ! extracellular matrix organization GO:0030198 103 61 0,000 0,10903867 0,11735561 ! amine catabolic process GO:0009310 90 62 0,000 0,11072639 0,11911632 ! neurotransmitter transport GO:0006836 81 62 0,000 0,11072639 0,11906063 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,11072639 0,119005 ! respiratory tube development GO:0030323 99 62 0,000 0,11072639 0,11894941 ! meiotic cell cycle GO:0051321 97 62 0,000 0,11072639 0,11889388 ! organelle localization GO:0051640 96 62 0,000 0,11072639 0,1188384 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,11241101 0,12059016 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,11241101 0,12053395 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,11241101 0,12047778 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,11241101 0,12042166 ! viral reproduction GO:0016032 92 63 0,000 0,11241101 0,1203656 ! regulation of lipase activity GO:0060191 109 63 0,000 0,11241101 0,12030959 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,11409253 0,12205247 ! appendage morphogenesis GO:0035107 93 64 0,000 0,11409253 0,12199573 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,11409253 0,12193904 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,11409253 0,1218824 ! hexose catabolic process GO:0019320 82 64 0,000 0,11409253 0,12182582 ! respiratory system development GO:0060541 100 64 0,000 0,11409253 0,12176929 ! adaptive immune response GO:0002250 94 64 0,000 0,11409253 0,12171281 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,11577096 0,12344609 ! appendage development GO:0048736 94 65 0,000 0,11577096 0,12338888 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,11577096 0,12333173 ! defense response to bacterium GO:0042742 73 65 0,000 0,11577096 0,12327463 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,11577096 0,12321759 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,11577096 0,1231606 ! activation of immune response GO:0002253 83 65 0,000 0,11577096 0,12310366 ! protein oligomerization GO:0051259 100 65 0,000 0,11577096 0,12304677 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,11744631 0,12476975 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,11744631 0,12471215 ! antigen processing and presentation GO:0019882 96 66 0,000 0,11744631 0,1246546 ! axon guidance GO:0007411 99 66 0,000 0,11744631 0,1245971 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,11744631 0,12453966 ! regulation of immune effector process GO:0002697 101 66 0,000 0,11744631 0,12448226 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,11911858 0,12619656 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,11911858 0,12613846 ! acute inflammatory response GO:0002526 92 68 0,000 0,12078778 0,12784717 ! learning or memory GO:0007611 123 68 0,000 0,12078778 0,12778836 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,12078778 0,12772961 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,12078778 0,12767091 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,12078778 0,12761226 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,12078778 0,12755367 ! rhythmic process GO:0048511 105 68 0,000 0,12078778 0,12749513 ! inorganic anion transport GO:0015698 93 68 0,000 0,12078778 0,12743665 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,12245391 0,12913526 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,12245391 0,12907607 ! response to drug GO:0042493 108 69 0,000 0,12245391 0,12901695 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,12411698 0,13070927 ! humoral immune response GO:0006959 86 70 0,000 0,12411698 0,13064945 ! amine transport GO:0015837 101 70 0,000 0,12411698 0,13058969 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,12411698 0,13052997 ! regulation of catabolic process GO:0009894 106 70 0,000 0,12411698 0,13047032 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,12577699 0,1321549 ! muscle cell differentiation GO:0042692 104 71 0,000 0,12577699 0,13209456 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,12577699 0,13203427 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,12577699 0,13197403 ! response to hypoxia GO:0001666 132 72 0,000 0,12743395 0,13365166 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,12743395 0,13359074 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,12743395 0,13352988 ! negative regulation of transport GO:0051051 116 73 0,000 0,12908787 0,13520132 ! regulation of blood pressure GO:0008217 107 73 0,000 0,12908787 0,13513978 ! tube morphogenesis GO:0035239 118 73 0,000 0,12908787 0,1350783 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,12908787 0,13501687 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,12908787 0,1349555 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,13073875 0,13661932 ! response to oxygen levels GO:0070482 137 74 0,000 0,13073875 0,13655727 ! digestion GO:0007586 97 74 0,000 0,13073875 0,13649529 ! protein import into nucleus GO:0006606 118 74 0,000 0,13073875 0,13643336 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,13073875 0,13637148 ! blood coagulation GO:0007596 116 75 0,000 0,13238659 0,13802772 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,13238659 0,13796518 ! nuclear import GO:0051170 121 75 0,000 0,13238659 0,13790269 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,13238659 0,13784027 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1340314 0,13948969 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1340314 0,1394266 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1340314 0,13936357 ! regulation of protein transport GO:0051223 114 76 0,000 0,1340314 0,1393006 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 0,000 0,13567319 0,14094324 ! regulation of DNA binding GO:0051101 119 77 0,000 0,13567319 0,14087961 ! gland development GO:0048732 148 77 0,000 0,13567319 0,14081603 ! sex differentiation GO:0007548 105 77 0,000 0,13567319 0,14075252 ! protein ubiquitination GO:0016567 125 77 0,000 0,13567319 0,14068906 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,13567319 0,14062566 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,13567319 0,14056231 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,13731196 0,14219608 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,13894771 0,14382527 ! T cell activation GO:0042110 134 79 0,000 0,13894771 0,14376057 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,13894771 0,14369593 ! chromatin assembly GO:0031497 102 80 0,000 0,14058046 0,14531913 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,14058046 0,14525385 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,14058046 0,14518862 ! forebrain development GO:0030900 131 80 0,000 0,14058046 0,14512346 ! hemostasis GO:0007599 125 81 0,000 0,14221021 0,14674001 ! mRNA transport GO:0051028 121 81 0,000 0,14221021 0,14667421 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,14221021 0,14660846 ! regulation of neurological system process GO:0031644 122 81 0,000 0,14221021 0,14654278 ! vitamin metabolic process GO:0006766 103 81 0,000 0,14221021 0,14647715 ! detection of stimulus GO:0051606 108 82 0,000 0,14383696 0,14808639 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,14546071 0,14969112 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,14546071 0,14962417 ! regulation of defense response GO:0031347 117 84 0,000 0,14708149 0,1512237 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,14708149 0,15115613 ! sterol metabolic process GO:0016125 120 84 0,000 0,14708149 0,15108862 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,14869928 0,15268229 ! rRNA metabolic process GO:0016072 107 85 0,000 0,14869928 0,15261416 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,14869928 0,15254609 ! transcription initiation GO:0006352 118 85 0,000 0,14869928 0,15247808 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,14869928 0,15241013 ! regulation of protein localization GO:0032880 132 85 0,000 0,14869928 0,15234224 ! regulation of membrane potential GO:0042391 128 85 0,000 0,14869928 0,15227441 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,14869928 0,15220665 ! nucleosome organization GO:0034728 114 87 0,000 0,15192593 0,15544024 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,15192593 0,15537112 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,15192593 0,15530207 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,15192593 0,15523307 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,15192593 0,15516414 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,15353481 0,15673771 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,15353481 0,15666818 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,15353481 0,1565987 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,15353481 0,15652929 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,15353481 0,15645993 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,15514073 0,15802643 ! reproductive developmental process GO:0003006 127 89 0,000 0,15514073 0,15795648 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,15514073 0,15788659 ! regulation of T cell activation GO:0050863 128 89 0,000 0,15514073 0,15781675 ! leukocyte differentiation GO:0002521 143 90 0,000 0,1567437 0,15937688 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,1567437 0,15930645 ! hormone metabolic process GO:0042445 121 90 0,000 0,1567437 0,15923609 ! RNA localization GO:0006403 135 91 0,000 0,15834371 0,16079052 ! ATP metabolic process GO:0046034 137 91 0,000 0,15834371 0,16071956 ! response to virus GO:0009615 122 91 0,000 0,15834371 0,16064867 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,15994078 0,16219744 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,15994078 0,16212596 ! cell fate commitment GO:0045165 141 92 0,000 0,15994078 0,16205454 ! positive regulation of immune response GO:0050778 121 92 0,000 0,15994078 0,16198318 ! DNA recombination GO:0006310 146 92 0,000 0,15994078 0,16191188 ! sulfur metabolic process GO:0006790 118 92 0,000 0,15994078 0,16184065 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,16153491 0,16338184 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,16153491 0,16331002 ! electron transport chain GO:0022900 123 94 0,000 0,16312611 0,16484625 ! response to oxidative stress GO:0006979 141 94 0,000 0,16312611 0,16477385 ! regulation of binding GO:0051098 151 95 0,000 0,16471438 0,16630513 ! angiogenesis GO:0001525 149 95 0,000 0,16471438 0,16623215 ! carboxylic acid transport GO:0046942 147 95 0,000 0,16471438 0,16615924 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,16629973 0,16768495 ! in utero embryonic development GO:0001701 147 96 0,000 0,16629973 0,16761147 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,16629973 0,16753805 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,16629973 0,1674647 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,16629973 0,16739141 ! protein maturation GO:0051604 129 96 0,000 0,16629973 0,16731819 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,16788216 0,16883645 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,16788216 0,16876266 ! calcium ion transport GO:0006816 167 99 0,000 0,17103828 0,17186022 ! extracellular structure organization GO:0043062 156 99 0,000 0,17103828 0,17178517 ! protein import GO:0017038 156 99 0,000 0,17103828 0,17171019 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,17103828 0,17163527 ! regulation of translation GO:0006417 151 100 0,000 0,17261199 0,17313893 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,17261199 0,17306346 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,17261199 0,17298805 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,17261199 0,17291271 ! divalent metal ion transport GO:0070838 171 100 0,000 0,17261199 0,17283743 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,17261199 0,17276222 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,17261199 0,17268707 ! protein localization in organelle GO:0033365 161 100 0,000 0,17261199 0,17261199