pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5501-6-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 6,867E-12 1,677E-08 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 5,000 1,561E-10 1,907E-07 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 5,000 2,029E-10 1,652E-07 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 5,000 2,029E-10 1,239E-07 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 2,872E-10 1,403E-07 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of ligase activity GO:0051351 130 77 5,000 3,067E-10 1,249E-07 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 5,000 3,59E-10 1,253E-07 ! regulation of ligase activity GO:0051340 147 84 5,000 5,228E-10 1,596E-07 ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 6,759E-10 1,835E-07 ! cell killing GO:0001906 32 15 3,000 1,859E-09 4,543E-07 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 5,586E-09 1,241E-06 ! polyol catabolic process GO:0046174 9 5 2,000 1,318E-08 2,684E-06 GO:0019405|alditol catabolic process, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 4,000 1,378E-08 2,59E-06 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 1,709E-08 2,983E-06 ! spindle organization GO:0007051 50 32 3,000 4,831E-08 7,869E-06 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 4,000 6,731E-08 1,028E-05 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 8,76E-08 1,259E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 2,168E-07 2,942E-05 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 3,746E-07 4,817E-05 ! fructose metabolic process GO:0006000 25 16 2,000 7,319E-07 8,94E-05 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 8,857E-07 1,03E-04 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,577E-06 1,751E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 1,731E-06 1,839E-04 ! osteoblast differentiation GO:0001649 63 26 2,000 3,371E-06 3,432E-04 ! alditol metabolic process GO:0019400 44 26 2,000 3,371E-06 3,295E-04 ! sperm motility GO:0030317 37 28 2,000 4,241E-06 3,985E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 6,402E-06 5,792E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 9,187E-06 8,015E-04 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 9,989E-06 8,415E-04 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,47E-05 1,197E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,813E-05 1,429E-03 ! polyol metabolic process GO:0019751 77 45 2,000 1,813E-05 1,384E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 1,847E-05 1,367E-03 GO:0046530|photoreceptor cell differentiation, ! response to UV GO:0009411 120 55 2,000 3,326E-05 2,39E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,443E-05 2,403E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 3,443E-05 2,336E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 4,423E-05 2,921E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 5,525E-05 3,552E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 5,525E-05 3,461E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 2,000 6,016E-05 3,675E-03 ! negative regulation of ligase activity GO:0051352 116 68 2,000 6,289E-05 3,747E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 6,57E-05 3,822E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 6,748E-05 3,834E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 6,748E-05 3,747E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 6,748E-05 3,663E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 6,859E-05 3,643E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 8,092E-05 4,206E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 8,092E-05 4,118E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 8,097E-05 4,037E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 9,556E-05 4,669E-03 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,114E-04 5,337E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,114E-04 5,234E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,14E-04 5,253E-03 ! regulation of cyclase activity GO:0031279 168 85 2,000 1,223E-04 5,534E-03 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,266E-04 5,625E-03 ! regulation of lyase activity GO:0051339 169 86 2,000 1,266E-04 5,525E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 1,311E-04 5,617E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,402E-04 5,905E-03 ! positive regulation of cell size GO:0045793 29 16 1,000 1,467E-04 6,075E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,497E-04 6,097E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,497E-04 5,997E-03 ! bone development GO:0060348 206 92 2,000 1,547E-04 6,095E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 1,648E-04 6,392E-03 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 1,662E-04 6,342E-03 ! membrane budding GO:0006900 42 17 1,000 1,662E-04 6,245E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 1,701E-04 6,296E-03 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 1,865E-04 6,799E-03 ! skin development GO:0043588 42 20 1,000 2,316E-04 8,322E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,316E-04 8,201E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,316E-04 8,084E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! cell-cell junction organization GO:0045216 43 20 1,000 2,316E-04 7,97E-03 ! positive regulation of B cell activation GO:0050871 42 22 1,000 2,812E-04 9,542E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 3,078E-04 0,01029975 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 3,355E-04 0,01107637 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 3,644E-04 0,01187055 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,644E-04 0,01171436 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 3,945E-04 0,01251683 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 3,945E-04 0,01235635 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 4,582E-04 0,01416929 ! fat cell differentiation GO:0045444 57 28 1,000 4,582E-04 0,01399217 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 4,918E-04 0,01483253 ! regulation of B cell activation GO:0050864 55 30 1,000 5,265E-04 0,01568702 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 5,625E-04 0,01655507 ! eye morphogenesis GO:0048592 65 31 1,000 5,625E-04 0,01635798 ! protein targeting to membrane GO:0006612 75 36 1,000 7,593E-04 0,02182391 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 7,593E-04 0,02157015 ! cell junction organization GO:0034330 96 37 1,000 8,021E-04 0,0225246 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 8,461E-04 0,02348907 ! glycogen metabolic process GO:0005977 63 38 1,000 8,461E-04 0,02322515 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 8,912E-04 0,02419134 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 8,912E-04 0,0239255 GO:0006073|cellular glucan metabolic process, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 9,848E-04 0,02615125 ! energy reserve metabolic process GO:0006112 76 44 1,000 1,134E-03 0,02978161 ! keratinocyte differentiation GO:0030216 81 45 1,000 1,186E-03 0,03081333 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,348E-03 0,03466495 ! response to calcium ion GO:0051592 94 49 1,000 1,404E-03 0,03573819 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,404E-03 0,03536975 ! epidermal cell differentiation GO:0009913 87 50 1,000 1,462E-03 0,03644163 ! positive regulation of growth GO:0045927 96 53 1,000 1,641E-03 0,04049262 ! vesicle organization GO:0016050 127 53 1,000 1,641E-03 0,0400877 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,641E-03 0,03969079 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 1,961E-03 0,04697771 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 2,237E-03 0,05306886 ! negative regulation of cell growth GO:0030308 142 67 1,000 2,607E-03 0,06123491 ! negative regulation of cell size GO:0045792 144 69 1,000 2,762E-03 0,06426372 ! actin filament organization GO:0007015 167 72 1,000 3,003E-03 0,06920819 ! regulation of caspase activity GO:0043281 136 74 1,000 3,169E-03 0,07234808 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,169E-03 0,07167819 ! eye development GO:0001654 155 75 1,000 3,253E-03 0,07291461 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 3,425E-03 0,07607527 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 3,513E-03 0,07731899 ! steroid biosynthetic process GO:0006694 146 79 1,000 3,602E-03 0,07856325 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 3,782E-03 0,08177044 ! regulation of peptidase activity GO:0052547 150 82 1,000 3,874E-03 0,08302059 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 3,967E-03 0,08427096 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 4,061E-03 0,0855215 ! negative regulation of growth GO:0045926 168 85 1,000 4,156E-03 0,08677215 ! positive regulation of cell activation GO:0050867 161 86 1,000 4,252E-03 0,08802286 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 4,349E-03 0,08927358 ! cellular respiration GO:0045333 143 88 1,000 4,447E-03 0,09052427 ! response to inorganic substance GO:0010035 173 90 1,000 4,646E-03 0,09379418 ! positive regulation of protein modification process GO:0031401 156 90 1,000 4,646E-03 0,09302538 ! response to unfolded protein GO:0006986 139 90 1,000 4,646E-03 0,09226907 ! response to protein stimulus GO:0051789 158 96 1,000 5,267E-03 0,10376611 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 5,614E-03 0,10972966 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 5,614E-03 0,10885879 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 5,614E-03 0,10800164 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,614E-03 0,10715788 ! positive regulation of helicase activity GO:0051096 12 5 0,000 5,614E-03 0,10632719 ! neuron fate determination GO:0048664 7 5 0,000 5,614E-03 0,10550929 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,614E-03 0,10470388 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 5,614E-03 0,10391067 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 5,614E-03 0,10312938 ! polyol transport GO:0015791 12 5 0,000 5,614E-03 0,10235976 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,614E-03 0,10160154 ! response to superoxide GO:0000303 10 5 0,000 5,614E-03 0,10085447 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,614E-03 0,10011831 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 5,614E-03 0,09939281 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 5,614E-03 0,09867776 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,614E-03 0,09797292 ! female meiosis GO:0007143 10 5 0,000 5,614E-03 0,09727807 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 5,614E-03 0,09659301 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,614E-03 0,09591754 ! hypothalamus development GO:0021854 9 5 0,000 5,614E-03 0,09525145 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 5,614E-03 0,09459454 ! cobalt ion transport GO:0006824 11 5 0,000 5,614E-03 0,09394663 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 5,614E-03 0,09330754 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 5,614E-03 0,09267708 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,614E-03 0,09205509 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,614E-03 0,09144139 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 5,614E-03 0,09083582 ! embryonic camera-type eye development GO:0031076 12 5 0,000 5,614E-03 0,09023821 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,614E-03 0,08964842 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,614E-03 0,08906629 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 5,614E-03 0,08849167 ! transposition GO:0032196 9 5 0,000 5,614E-03 0,08792441 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 5,614E-03 0,08736438 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 5,614E-03 0,08681144 ! negative chemotaxis GO:0050919 16 5 0,000 5,614E-03 0,08626546 ! positive regulation of histone modification GO:0031058 6 5 0,000 5,614E-03 0,0857263 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,614E-03 0,08519384 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 5,614E-03 0,08466795 ! behavioral response to pain GO:0048266 10 5 0,000 5,614E-03 0,08414852 ! clathrin coat assembly GO:0048268 15 5 0,000 5,614E-03 0,08363542 ! Notch receptor processing GO:0007220 11 5 0,000 5,614E-03 0,08312853 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,614E-03 0,08262776 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 5,614E-03 0,08213298 ! micturition GO:0060073 9 5 0,000 5,614E-03 0,0816441 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,614E-03 0,08116099 ! copulation GO:0007620 9 5 0,000 5,614E-03 0,08068358 ! glial cell fate commitment GO:0021781 14 5 0,000 5,614E-03 0,08021174 ! protein maturation by protein folding GO:0022417 14 5 0,000 5,614E-03 0,0797454 ! bioluminescence GO:0008218 9 5 0,000 5,614E-03 0,07928444 ! spermidine metabolic process GO:0008216 7 5 0,000 5,614E-03 0,07882878 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,614E-03 0,07837833 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,614E-03 0,077933 ! apoptotic cell clearance GO:0043277 23 5 0,000 5,614E-03 0,0774927 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,614E-03 0,07705735 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 5,614E-03 0,07662686 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,614E-03 0,07620116 ! grooming behavior GO:0007625 6 5 0,000 5,614E-03 0,07578016 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 5,614E-03 0,07536378 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,614E-03 0,07495196 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 5,614E-03 0,07454461 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,614E-03 0,07414167 ! response to protozoan GO:0001562 13 5 0,000 5,614E-03 0,07374305 ! positive regulation of glycolysis GO:0045821 13 5 0,000 5,614E-03 0,07334871 ! lymph vessel development GO:0001945 10 5 0,000 5,614E-03 0,07295855 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 5,614E-03 0,07257253 ! endochondral ossification GO:0001958 17 5 0,000 5,614E-03 0,07219057 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,614E-03 0,07181261 ! single strand break repair GO:0000012 8 5 0,000 5,614E-03 0,07143858 ! parathyroid gland development GO:0060017 14 5 0,000 5,614E-03 0,07106844 ! anagen GO:0042640 7 5 0,000 5,614E-03 0,0707021 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,614E-03 0,07033953 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,614E-03 0,06998065 ! cytokine secretion GO:0050663 15 5 0,000 5,614E-03 0,06962542 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 5,614E-03 0,06927378 ! ceramide catabolic process GO:0046514 7 5 0,000 5,614E-03 0,06892567 ! skeletal myofibril assembly GO:0014866 12 5 0,000 5,614E-03 0,06858104 ! smooth muscle tissue development GO:0048745 32 5 0,000 5,614E-03 0,06823984 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,614E-03 0,06790202 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,614E-03 0,06756753 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,614E-03 0,06723631 ! cardiac muscle fiber development GO:0048739 12 5 0,000 5,614E-03 0,06690833 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,614E-03 0,06658353 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 5,614E-03 0,06626187 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,614E-03 0,06594331 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 5,614E-03 0,06562779 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,614E-03 0,06531528 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 5,614E-03 0,06500573 ! glycine biosynthetic process GO:0006545 7 5 0,000 5,614E-03 0,06469909 ! microvillus organization GO:0032528 8 5 0,000 5,614E-03 0,06439534 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 5,614E-03 0,06409443 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 5,614E-03 0,06379632 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 5,614E-03 0,06350096 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 5,614E-03 0,06320833 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 5,614E-03 0,06291839 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 5,614E-03 0,06263109 ! polyol biosynthetic process GO:0046173 6 5 0,000 5,614E-03 0,0623464 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 5,614E-03 0,06206429 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,614E-03 0,06178472 ! muscle cell migration GO:0014812 8 5 0,000 5,614E-03 0,06150766 ! mitochondrial fission GO:0000266 8 5 0,000 5,614E-03 0,06123307 ! sister chromatid cohesion GO:0007062 15 5 0,000 5,614E-03 0,06096092 ! response to tumor necrosis factor GO:0034612 10 5 0,000 5,614E-03 0,06069119 ! mRNA transcription GO:0009299 10 5 0,000 5,614E-03 0,06042382 ! nerve growth factor processing GO:0032455 9 5 0,000 5,614E-03 0,06015881 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 5,614E-03 0,05989611 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 5,614E-03 0,05963569 ! anaerobic glycolysis GO:0019642 6 5 0,000 5,614E-03 0,05937752 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,614E-03 0,05912159 ! monocyte activation GO:0042117 10 5 0,000 5,614E-03 0,05886785 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,614E-03 0,05861627 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,614E-03 0,05836684 ! response to food GO:0032094 6 5 0,000 5,614E-03 0,05811953 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,614E-03 0,0578743 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,614E-03 0,05763113 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 5,614E-03 0,05738999 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,614E-03 0,05715087 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 5,614E-03 0,05691373 ! forebrain neuron development GO:0021884 13 5 0,000 5,614E-03 0,05667855 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,614E-03 0,0564453 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 5,614E-03 0,05621397 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 5,614E-03 0,05598452 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,614E-03 0,05575694 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,614E-03 0,05553121 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 5,614E-03 0,05530729 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,614E-03 0,05508517 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 5,614E-03 0,05486483 ! lipid glycosylation GO:0030259 7 5 0,000 5,614E-03 0,05464625 ! nucleobase transport GO:0015851 6 5 0,000 5,614E-03 0,0544294 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,614E-03 0,05421426 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 5,614E-03 0,05400082 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 5,614E-03 0,05378905 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 5,614E-03 0,05357894 ! basic amino acid transport GO:0015802 12 5 0,000 5,614E-03 0,05337046 ! cellular glucose homeostasis GO:0001678 6 5 0,000 5,614E-03 0,0531636 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 5,614E-03 0,05295833 ! actin nucleation GO:0045010 11 5 0,000 5,614E-03 0,05275465 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,614E-03 0,05255252 ! depurination GO:0045007 5 5 0,000 5,614E-03 0,05235194 ! depyrimidination GO:0045008 10 5 0,000 5,614E-03 0,05215288 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,614E-03 0,05195533 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,614E-03 0,05175928 ! G2/M transition checkpoint GO:0031576 8 5 0,000 5,614E-03 0,05156469 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,614E-03 0,05137157 ! zinc ion homeostasis GO:0055069 9 5 0,000 5,614E-03 0,05117988 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 5,614E-03 0,05098962 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 5,614E-03 0,05080077 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,614E-03 0,05061331 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,614E-03 0,05042724 ! activated T cell proliferation GO:0050798 16 5 0,000 5,614E-03 0,05024252 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,614E-03 0,05005915 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 5,614E-03 0,04987712 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,614E-03 0,04969641 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,614E-03 0,049517 ! gamma-delta T cell activation GO:0046629 6 5 0,000 5,614E-03 0,04933888 ! response to arsenic GO:0046685 11 5 0,000 5,614E-03 0,04916204 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 5,614E-03 0,04898646 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,614E-03 0,04881213 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 5,614E-03 0,04863904 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 5,614E-03 0,04846717 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 5,614E-03 0,04829651 ! response to mercury ion GO:0046689 8 5 0,000 5,614E-03 0,04812705 ! response to cadmium ion GO:0046686 7 5 0,000 5,614E-03 0,04795877 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 5,614E-03 0,04779167 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 5,614E-03 0,04762572 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 5,614E-03 0,04746093 ! bile acid biosynthetic process GO:0006699 7 5 0,000 5,614E-03 0,04729727 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,614E-03 0,04713474 ! ganglioside catabolic process GO:0006689 12 5 0,000 5,614E-03 0,04697332 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,614E-03 0,046813 ! decidualization GO:0046697 11 5 0,000 5,614E-03 0,04665377 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 5,614E-03 0,04649562 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 5,614E-03 0,04633854 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 5,614E-03 0,04618252 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 5,614E-03 0,04602754 ! embryonic cleavage GO:0040016 6 5 0,000 5,614E-03 0,04587361 ! peroxisome fission GO:0016559 5 5 0,000 5,614E-03 0,04572069 ! histone demethylation GO:0016577 13 5 0,000 5,614E-03 0,0455688 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 5,614E-03 0,04541791 ! mitotic recombination GO:0006312 9 5 0,000 5,614E-03 0,04526801 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 5,614E-03 0,04511911 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,614E-03 0,04497117 ! metaphase plate congression GO:0051310 7 5 0,000 5,614E-03 0,04482421 ! regulation of sterol transport GO:0032371 7 5 0,000 5,614E-03 0,0446782 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,614E-03 0,04453314 ! enteric nervous system development GO:0048484 8 5 0,000 5,614E-03 0,04438902 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 5,614E-03 0,04424583 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 5,614E-03 0,04410356 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 5,614E-03 0,04396221 ! muscle cell proliferation GO:0033002 12 5 0,000 5,614E-03 0,04382175 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,614E-03 0,04368219 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 5,614E-03 0,04354352 ! B cell homeostasis GO:0001782 13 5 0,000 5,614E-03 0,04340572 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 5,614E-03 0,0432688 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,614E-03 0,04313273 ! metaphase GO:0051323 11 5 0,000 5,614E-03 0,04299752 ! melatonin biosynthetic process GO:0030187 7 5 0,000 5,614E-03 0,04286315 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 5,614E-03 0,04272962 ! cellular response to nutrient GO:0031670 8 5 0,000 5,614E-03 0,04259692 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,614E-03 0,04246504 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 5,614E-03 0,04233398 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 5,614E-03 0,04220372 ! regulation of hair follicle development GO:0051797 10 5 0,000 5,614E-03 0,04207426 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 5,614E-03 0,04194559 ! response to redox state GO:0051775 6 5 0,000 5,614E-03 0,04181771 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 5,614E-03 0,0416906 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 5,614E-03 0,04156427 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,614E-03 0,0414387 ! brown fat cell differentiation GO:0050873 7 5 0,000 5,614E-03 0,04131388 ! regulation of telomerase activity GO:0051972 7 5 0,000 5,614E-03 0,04118981 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,614E-03 0,04106649 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 5,614E-03 0,0409439 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,614E-03 0,04082205 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 5,614E-03 0,04070091 ! striatum development GO:0021756 14 5 0,000 5,614E-03 0,0405805 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 5,614E-03 0,04046079 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,614E-03 0,04034179 ! glial cell migration GO:0008347 10 5 0,000 5,614E-03 0,04022348 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,614E-03 0,04010587 ! neural plate morphogenesis GO:0001839 7 5 0,000 5,614E-03 0,03998894 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 5,614E-03 0,0398727 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,614E-03 0,03975712 ! T cell activation during immune response GO:0002286 9 5 0,000 5,614E-03 0,03964222 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,614E-03 0,03952798 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,614E-03 0,03941439 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 5,614E-03 0,03930146 ! neuroprotection GO:0043526 8 5 0,000 5,614E-03 0,03918917 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,614E-03 0,03907752 ! regulation of sensory perception GO:0051931 8 5 0,000 5,614E-03 0,0389665 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,614E-03 0,03885611 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,614E-03 0,03874635 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 5,614E-03 0,03863721 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 5,614E-03 0,03852867 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,614E-03 0,03842075 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 5,614E-03 0,03831343 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,614E-03 0,03820671 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 5,614E-03 0,03810058 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 5,614E-03 0,03799504 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 5,614E-03 0,03789008 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,614E-03 0,0377857 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,614E-03 0,03768189 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,614E-03 0,03757865 ! protein palmitoylation GO:0018345 12 5 0,000 5,614E-03 0,03747598 ! drug metabolic process GO:0017144 7 5 0,000 5,614E-03 0,03737386 ! stem cell division GO:0017145 11 5 0,000 5,614E-03 0,0372723 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,614E-03 0,0371713 ! organ regeneration GO:0031100 7 5 0,000 5,614E-03 0,03707083 ! carnitine metabolic process GO:0009437 8 5 0,000 5,614E-03 0,03697091 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,614E-03 0,03687153 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,734E-03 0,04410302 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,734E-03 0,04398509 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 6,734E-03 0,0438678 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 6,734E-03 0,04375113 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,734E-03 0,04363508 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 6,734E-03 0,04351964 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 6,734E-03 0,04340482 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,734E-03 0,04329059 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 6,734E-03 0,04317697 ! response to oxygen radical GO:0000305 11 6 0,000 6,734E-03 0,04306394 ! positive regulation of axon extension GO:0045773 13 6 0,000 6,734E-03 0,0429515 ! myoblast cell fate commitment GO:0048625 18 6 0,000 6,734E-03 0,04283965 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 6,734E-03 0,04272838 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 6,734E-03 0,04261768 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,734E-03 0,04250756 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,734E-03 0,042398 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 6,734E-03 0,04228901 ! forebrain regionalization GO:0021871 9 6 0,000 6,734E-03 0,04218058 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,734E-03 0,0420727 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,734E-03 0,04196537 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 6,734E-03 0,04185859 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,734E-03 0,04175235 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 6,734E-03 0,04164665 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 6,734E-03 0,04154148 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,734E-03 0,04143684 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 6,734E-03 0,04133273 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 6,734E-03 0,04122914 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,734E-03 0,04112606 ! malate metabolic process GO:0006108 13 6 0,000 6,734E-03 0,0410235 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 6,734E-03 0,04092146 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 6,734E-03 0,04081991 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 6,734E-03 0,04071887 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 6,734E-03 0,04061833 ! protein refolding GO:0042026 15 6 0,000 6,734E-03 0,04051829 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,734E-03 0,04041874 ! opsonization GO:0008228 8 6 0,000 6,734E-03 0,04031967 ! mating behavior GO:0007617 7 6 0,000 6,734E-03 0,04022109 ! erythrocyte maturation GO:0043249 8 6 0,000 6,734E-03 0,04012299 ! embryonic hemopoiesis GO:0035162 16 6 0,000 6,734E-03 0,04002537 ! protein amino acid dealkylation GO:0008214 15 6 0,000 6,734E-03 0,03992822 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 6,734E-03 0,03983154 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,734E-03 0,03973533 ! response to interferon-gamma GO:0034341 16 6 0,000 6,734E-03 0,03963958 ! toxin metabolic process GO:0009404 11 6 0,000 6,734E-03 0,03954429 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,734E-03 0,03944946 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 6,734E-03 0,03935508 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 6,734E-03 0,03926116 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 6,734E-03 0,03916768 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 6,734E-03 0,03907464 ! cGMP-mediated signaling GO:0019934 14 6 0,000 6,734E-03 0,03898205 ! dorsal spinal cord development GO:0021516 10 6 0,000 6,734E-03 0,03888989 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,734E-03 0,03879817 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 6,734E-03 0,03870688 ! thymic T cell selection GO:0045061 16 6 0,000 6,734E-03 0,03861602 ! sphingoid catabolic process GO:0046521 8 6 0,000 6,734E-03 0,03852559 ! protein lipoylation GO:0009249 10 6 0,000 6,734E-03 0,03843557 ! transepithelial chloride transport GO:0030321 12 6 0,000 6,734E-03 0,03834598 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 6,734E-03 0,0382568 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,734E-03 0,03816804 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 6,734E-03 0,03807969 ! glutamate catabolic process GO:0006538 12 6 0,000 6,734E-03 0,03799174 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 6,734E-03 0,03790421 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,734E-03 0,03781707 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 6,734E-03 0,03773033 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,734E-03 0,03764399 ! hyperosmotic response GO:0006972 10 6 0,000 6,734E-03 0,03755805 ! L-serine biosynthetic process GO:0006564 7 6 0,000 6,734E-03 0,0374725 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 6,734E-03 0,03738733 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 6,734E-03 0,03730255 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,734E-03 0,03721816 ! urea metabolic process GO:0019627 7 6 0,000 6,734E-03 0,03713414 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,734E-03 0,03705051 ! neutrophil activation GO:0042119 7 6 0,000 6,734E-03 0,03696725 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,734E-03 0,03688436 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 6,734E-03 0,03680185 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,734E-03 0,0367197 ! paraxial mesoderm development GO:0048339 16 6 0,000 6,734E-03 0,03663792 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 6,734E-03 0,0365565 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,734E-03 0,03647544 ! neuron apoptosis GO:0051402 15 6 0,000 6,734E-03 0,03639475 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 6,734E-03 0,03631441 ! T cell mediated immunity GO:0002456 17 6 0,000 6,734E-03 0,03623442 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,734E-03 0,03615478 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 6,734E-03 0,03607549 ! carnitine transport GO:0015879 10 6 0,000 6,734E-03 0,03599655 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,734E-03 0,03591796 ! positive regulation of exocytosis GO:0045921 11 6 0,000 6,734E-03 0,03583971 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 6,734E-03 0,03576179 ! early endosome to late endosome transport GO:0045022 16 6 0,000 6,734E-03 0,03568422 ! 5S class rRNA transcription GO:0042791 13 6 0,000 6,734E-03 0,03560698 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,734E-03 0,03553008 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 6,734E-03 0,0354535 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 6,734E-03 0,03537726 ! sodium ion homeostasis GO:0055078 12 6 0,000 6,734E-03 0,03530134 ! establishment of spindle localization GO:0051293 16 6 0,000 6,734E-03 0,03522575 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 6,734E-03 0,03515048 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,734E-03 0,03507553 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 6,734E-03 0,03500091 ! response to UV-C GO:0010225 14 6 0,000 6,734E-03 0,03492659 ! astrocyte development GO:0014002 16 6 0,000 6,734E-03 0,0348526 ! protein targeting to lysosome GO:0006622 12 6 0,000 6,734E-03 0,03477891 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,734E-03 0,03470554 ! interaction with symbiont GO:0051702 14 6 0,000 6,734E-03 0,03463247 ! regulation of dendrite development GO:0050773 16 6 0,000 6,734E-03 0,03455972 ! peptidyl-arginine modification GO:0018195 13 6 0,000 6,734E-03 0,03448727 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 6,734E-03 0,03441512 ! response to copper ion GO:0046688 10 6 0,000 6,734E-03 0,03434327 ! response to exogenous dsRNA GO:0043330 13 6 0,000 6,734E-03 0,03427172 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 6,734E-03 0,03420047 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,734E-03 0,03412951 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 6,734E-03 0,03405885 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,734E-03 0,03398848 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 6,734E-03 0,0339184 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,734E-03 0,03384861 ! nucleoside catabolic process GO:0009164 10 6 0,000 6,734E-03 0,03377911 ! hair follicle maturation GO:0048820 8 6 0,000 6,734E-03 0,03370989 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,734E-03 0,03364095 ! Schwann cell development GO:0014044 15 6 0,000 6,734E-03 0,0335723 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 6,734E-03 0,03350392 ! response to pheromone GO:0019236 6 6 0,000 6,734E-03 0,03343582 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 6,734E-03 0,033368 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 6,734E-03 0,03330046 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 6,734E-03 0,03323318 ! base conversion or substitution editing GO:0016553 6 6 0,000 6,734E-03 0,03316618 ! subpallium development GO:0021544 15 6 0,000 6,734E-03 0,03309945 ! neural tube patterning GO:0021532 8 6 0,000 6,734E-03 0,03303298 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 6,734E-03 0,03296678 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 6,734E-03 0,03290085 ! maintenance of organ identity GO:0048496 9 6 0,000 6,734E-03 0,03283518 ! G2 phase GO:0051319 16 6 0,000 6,734E-03 0,03276977 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 6,734E-03 0,03270462 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 6,734E-03 0,03263973 ! oxygen homeostasis GO:0032364 10 6 0,000 6,734E-03 0,0325751 ! establishment of planar polarity GO:0001736 7 6 0,000 6,734E-03 0,03251072 ! regulation of mast cell activation GO:0033003 13 6 0,000 6,734E-03 0,0324466 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,734E-03 0,03238273 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 6,734E-03 0,03231911 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,734E-03 0,03225574 ! receptor internalization GO:0031623 11 6 0,000 6,734E-03 0,03219261 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 6,734E-03 0,03212974 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 6,734E-03 0,03206711 ! neutrophil homeostasis GO:0001780 11 6 0,000 6,734E-03 0,03200472 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,734E-03 0,03194257 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 6,734E-03 0,03188067 ! protein deubiquitination GO:0016579 16 6 0,000 6,734E-03 0,031819 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 6,734E-03 0,03175758 ! protein destabilization GO:0031648 9 6 0,000 6,734E-03 0,03169639 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 6,734E-03 0,03163543 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,734E-03 0,03157471 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 6,734E-03 0,03151423 ! regulation of viral transcription GO:0046782 11 6 0,000 6,734E-03 0,03145397 ! progesterone metabolic process GO:0042448 12 6 0,000 6,734E-03 0,03139394 ! negative regulation of axon extension GO:0030517 24 6 0,000 6,734E-03 0,03133414 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 6,734E-03 0,03127457 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 6,734E-03 0,03121523 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,734E-03 0,03115611 ! determination of adult lifespan GO:0008340 17 6 0,000 6,734E-03 0,03109721 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 6,734E-03 0,03103854 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 6,734E-03 0,03098009 ! neural plate development GO:0001840 9 6 0,000 6,734E-03 0,03092185 ! catecholamine transport GO:0051937 9 6 0,000 6,734E-03 0,03086384 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 6,734E-03 0,03080604 ! sensory cilium assembly GO:0035058 10 6 0,000 6,734E-03 0,03074846 ! organ or tissue specific immune response GO:0002251 8 6 0,000 6,734E-03 0,03069109 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 6,734E-03 0,03063394 ! maternal placenta development GO:0001893 12 6 0,000 6,734E-03 0,030577 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 6,734E-03 0,03052027 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,734E-03 0,03046375 ! negative regulation of B cell activation GO:0050869 14 6 0,000 6,734E-03 0,03040744 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 6,734E-03 0,03035134 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 6,734E-03 0,03029544 ! positive regulation of coagulation GO:0050820 13 6 0,000 6,734E-03 0,03023975 ! cellular anion homeostasis GO:0030002 11 6 0,000 6,734E-03 0,03018427 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 7,852E-03 0,03513121 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 7,852E-03 0,03506699 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 7,852E-03 0,035003 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,852E-03 0,03493924 ! regulation of helicase activity GO:0051095 16 7 0,000 7,852E-03 0,03487571 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 7,852E-03 0,03481242 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 7,852E-03 0,03474935 ! sleep GO:0030431 16 7 0,000 7,852E-03 0,03468651 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,852E-03 0,0346239 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 7,852E-03 0,03456152 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,852E-03 0,03449936 ! prostate gland development GO:0030850 14 7 0,000 7,852E-03 0,03443742 ! nucleotide-sugar transport GO:0015780 11 7 0,000 7,852E-03 0,0343757 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,852E-03 0,03431421 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,852E-03 0,03425293 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 7,852E-03 0,03419188 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,852E-03 0,03413104 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 7,852E-03 0,03407041 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 7,852E-03 0,03401 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,852E-03 0,03394981 ! SMAD protein complex assembly GO:0007183 13 7 0,000 7,852E-03 0,03388983 ! glycolipid transport GO:0046836 11 7 0,000 7,852E-03 0,03383006 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,852E-03 0,0337705 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 7,852E-03 0,03371115 ! neuron adhesion GO:0007158 14 7 0,000 7,852E-03 0,033652 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 7,852E-03 0,03359307 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,852E-03 0,03353434 ! establishment of tissue polarity GO:0007164 8 7 0,000 7,852E-03 0,03347582 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 7,852E-03 0,0334175 ! mRNA stabilization GO:0048255 18 7 0,000 7,852E-03 0,03335938 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 7,852E-03 0,03330146 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 7,852E-03 0,03324375 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 7,852E-03 0,03318623 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 7,852E-03 0,03312892 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,852E-03 0,0330718 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,852E-03 0,03301487 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,852E-03 0,03295815 ! lipoprotein transport GO:0042953 14 7 0,000 7,852E-03 0,03290162 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 7,852E-03 0,03284528 ! rhythmic behavior GO:0007622 17 7 0,000 7,852E-03 0,03278913 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 7,852E-03 0,03273318 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 7,852E-03 0,03267741 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 7,852E-03 0,03262184 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 7,852E-03 0,03256646 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,852E-03 0,03251126 ! regulation of odontogenesis GO:0042481 14 7 0,000 7,852E-03 0,03245625 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,852E-03 0,03240142 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 7,852E-03 0,03234678 ! mechanosensory behavior GO:0007638 16 7 0,000 7,852E-03 0,03229233 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 7,852E-03 0,03223805 ! positive regulation of isotype switching GO:0045830 17 7 0,000 7,852E-03 0,03218396 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 7,852E-03 0,03213005 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 7,852E-03 0,03207632 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,852E-03 0,03202278 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,852E-03 0,0319694 ! spinal cord patterning GO:0021511 14 7 0,000 7,852E-03 0,03191621 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 7,852E-03 0,03186319 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 7,852E-03 0,03181035 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,852E-03 0,03175769 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 7,852E-03 0,03170519 ! adrenal gland development GO:0030325 17 7 0,000 7,852E-03 0,03165288 ! cysteine metabolic process GO:0006534 13 7 0,000 7,852E-03 0,03160073 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 7,852E-03 0,03154875 ! ovulation GO:0030728 10 7 0,000 7,852E-03 0,03149695 ! adenohypophysis development GO:0021984 11 7 0,000 7,852E-03 0,03144532 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 7,852E-03 0,03139385 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 7,852E-03 0,03134255 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 7,852E-03 0,03129142 ! microtubule nucleation GO:0007020 21 7 0,000 7,852E-03 0,03124046 ! proline biosynthetic process GO:0006561 10 7 0,000 7,852E-03 0,03118966 ! tryptophan metabolic process GO:0006568 11 7 0,000 7,852E-03 0,03113903 ! thyroid hormone generation GO:0006590 13 7 0,000 7,852E-03 0,03108856 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 7,852E-03 0,03103826 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 7,852E-03 0,03098811 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,852E-03 0,03093813 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 7,852E-03 0,03088831 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 7,852E-03 0,03083865 ! galactose metabolic process GO:0006012 13 7 0,000 7,852E-03 0,03078915 ! vesicle fusion GO:0006906 20 7 0,000 7,852E-03 0,03073981 ! response to dietary excess GO:0002021 8 7 0,000 7,852E-03 0,03069063 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,852E-03 0,0306416 ! intracellular pH reduction GO:0051452 13 7 0,000 7,852E-03 0,03059273 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,852E-03 0,03054402 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 7,852E-03 0,03049546 ! organ growth GO:0035265 15 7 0,000 7,852E-03 0,03044705 ! nucleoside transport GO:0015858 11 7 0,000 7,852E-03 0,0303988 ! nucleoside salvage GO:0043174 11 7 0,000 7,852E-03 0,0303507 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 7,852E-03 0,03030275 ! male sex determination GO:0030238 15 7 0,000 7,852E-03 0,03025496 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 7,852E-03 0,03020731 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 7,852E-03 0,03015981 ! parturition GO:0007567 16 7 0,000 7,852E-03 0,03011247 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 7,852E-03 0,03006527 ! rRNA modification GO:0000154 14 7 0,000 7,852E-03 0,03001822 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 7,852E-03 0,02997132 ! spindle checkpoint GO:0031577 16 7 0,000 7,852E-03 0,02992456 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 7,852E-03 0,02987795 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 7,852E-03 0,02983148 ! monocyte differentiation GO:0030224 16 7 0,000 7,852E-03 0,02978516 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 7,852E-03 0,02973898 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,852E-03 0,02969294 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 7,852E-03 0,02964705 ! hyaluronan metabolic process GO:0030212 9 7 0,000 7,852E-03 0,0296013 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 7,852E-03 0,02955569 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,852E-03 0,02951022 ! fibrinolysis GO:0042730 11 7 0,000 7,852E-03 0,02946489 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 7,852E-03 0,0294197 ! skeletal muscle contraction GO:0003009 8 7 0,000 7,852E-03 0,02937464 ! eating behavior GO:0042755 8 7 0,000 7,852E-03 0,02932973 ! B cell lineage commitment GO:0002326 21 7 0,000 7,852E-03 0,02928495 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,852E-03 0,02924031 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 7,852E-03 0,0291958 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 7,852E-03 0,02915143 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,852E-03 0,0291072 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 7,852E-03 0,02906309 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,852E-03 0,02901913 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 7,852E-03 0,02897529 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 7,852E-03 0,02893159 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 7,852E-03 0,02888802 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 7,852E-03 0,02884457 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,852E-03 0,02880126 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 7,852E-03 0,02875808 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 7,852E-03 0,02871503 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,852E-03 0,02867211 ! histone ubiquitination GO:0016574 9 7 0,000 7,852E-03 0,02862932 ! regulation of meiosis GO:0040020 12 7 0,000 7,852E-03 0,02858665 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 7,852E-03 0,02854411 ! T cell lineage commitment GO:0002360 16 7 0,000 7,852E-03 0,0285017 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 7,852E-03 0,02845941 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,852E-03 0,02841725 ! membrane to membrane docking GO:0022614 14 7 0,000 7,852E-03 0,02837521 ! transcription termination GO:0006353 14 7 0,000 7,852E-03 0,0283333 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,852E-03 0,02829151 ! anaphase GO:0051322 18 7 0,000 7,852E-03 0,02824984 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 7,852E-03 0,0282083 ! axonal fasciculation GO:0007413 19 7 0,000 7,852E-03 0,02816688 ! negative regulation of nuclear division GO:0051784 15 7 0,000 7,852E-03 0,02812558 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 7,852E-03 0,0280844 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 7,852E-03 0,02804334 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 7,852E-03 0,0280024 ! diuresis GO:0030146 12 7 0,000 7,852E-03 0,02796158 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,852E-03 0,02792088 ! thiamin metabolic process GO:0006772 7 7 0,000 7,852E-03 0,02788029 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,852E-03 0,02783983 ! antibiotic transport GO:0042891 9 7 0,000 7,852E-03 0,02779948 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,852E-03 0,02775925 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 7,852E-03 0,02771914 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 7,852E-03 0,02767914 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 7,852E-03 0,02763925 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 7,852E-03 0,02759949 ! melanin biosynthetic process GO:0042438 10 7 0,000 7,852E-03 0,02755983 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 7,852E-03 0,02752029 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,852E-03 0,02748086 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,852E-03 0,02744155 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 7,852E-03 0,02740235 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 7,852E-03 0,02736326 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 7,852E-03 0,02732428 ! endosome to lysosome transport GO:0008333 12 7 0,000 7,852E-03 0,02728541 ! protein modification by small protein removal GO:0070646 19 7 0,000 7,852E-03 0,02724665 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 7,852E-03 0,027208 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 7,852E-03 0,02716947 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 7,852E-03 0,02713104 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 7,852E-03 0,02709272 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,852E-03 0,0270545 ! muscle adaptation GO:0043500 13 7 0,000 7,852E-03 0,0270164 ! embryonic heart tube development GO:0035050 14 7 0,000 7,852E-03 0,0269784 ! retina homeostasis GO:0001895 12 7 0,000 7,852E-03 0,02694051 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 7,852E-03 0,02690272 ! protein amino acid prenylation GO:0018346 19 7 0,000 7,852E-03 0,02686505 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 7,852E-03 0,02682747 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 7,852E-03 0,02679 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 8,968E-03 0,03055769 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 8,968E-03 0,03051513 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 8,968E-03 0,03047269 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 8,968E-03 0,03043036 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 8,968E-03 0,03038816 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,968E-03 0,03034607 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,968E-03 0,0303041 ! male meiosis GO:0007140 9 8 0,000 8,968E-03 0,03026224 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 8,968E-03 0,0302205 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 8,968E-03 0,03017887 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 8,968E-03 0,03013736 ! meiotic prophase I GO:0007128 14 8 0,000 8,968E-03 0,03009596 ! response to zinc ion GO:0010043 12 8 0,000 8,968E-03 0,03005468 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 8,968E-03 0,03001351 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,968E-03 0,02997245 ! oligopeptide transport GO:0006857 16 8 0,000 8,968E-03 0,02993151 ! actin-myosin filament sliding GO:0033275 13 8 0,000 8,968E-03 0,02989067 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 8,968E-03 0,02984995 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 8,968E-03 0,02980934 ! signal peptide processing GO:0006465 12 8 0,000 8,968E-03 0,02976883 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 8,968E-03 0,02972844 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 8,968E-03 0,02968816 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,968E-03 0,02964799 ! succinate metabolic process GO:0006105 17 8 0,000 8,968E-03 0,02960792 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 8,968E-03 0,02956796 ! membrane hyperpolarization GO:0060081 11 8 0,000 8,968E-03 0,02952812 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,968E-03 0,02948837 ! estrogen metabolic process GO:0008210 17 8 0,000 8,968E-03 0,02944874 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 8,968E-03 0,02940921 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,968E-03 0,02936979 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 8,968E-03 0,02933047 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 8,968E-03 0,02929126 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,968E-03 0,02925215 ! reflex GO:0060004 17 8 0,000 8,968E-03 0,02921315 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,968E-03 0,02917425 ! glycerolipid catabolic process GO:0046503 14 8 0,000 8,968E-03 0,02913545 ! hemoglobin metabolic process GO:0020027 14 8 0,000 8,968E-03 0,02909676 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,968E-03 0,02905817 ! pigment granule organization GO:0048753 17 8 0,000 8,968E-03 0,02901968 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,968E-03 0,0289813 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 8,968E-03 0,02894301 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 8,968E-03 0,02890483 ! astrocyte differentiation GO:0048708 19 8 0,000 8,968E-03 0,02886675 ! histidine catabolic process GO:0006548 10 8 0,000 8,968E-03 0,02882877 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 8,968E-03 0,02879088 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 8,968E-03 0,0287531 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 8,968E-03 0,02871542 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 8,968E-03 0,02867783 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 8,968E-03 0,02864034 ! regulation of pigmentation during development GO:0048070 25 8 0,000 8,968E-03 0,02860295 ! melanin metabolic process GO:0006582 17 8 0,000 8,968E-03 0,02856566 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 8,968E-03 0,02852847 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 8,968E-03 0,02849137 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 8,968E-03 0,02845437 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,968E-03 0,02841746 ! macrophage activation GO:0042116 13 8 0,000 8,968E-03 0,02838065 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,968E-03 0,02834393 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,968E-03 0,02830731 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 8,968E-03 0,02827079 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,968E-03 0,02823436 ! purine salvage GO:0043101 12 8 0,000 8,968E-03 0,02819802 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 8,968E-03 0,02816178 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,968E-03 0,02812562 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 8,968E-03 0,02808957 ! osteoblast development GO:0002076 17 8 0,000 8,968E-03 0,0280536 ! positive regulation of vasodilation GO:0045909 14 8 0,000 8,968E-03 0,02801773 ! negative regulation of translational initiation GO:0045947 12 8 0,000 8,968E-03 0,02798194 ! Schwann cell differentiation GO:0014037 21 8 0,000 8,968E-03 0,02794625 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 8,968E-03 0,02791065 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,968E-03 0,02787514 ! response to UV-B GO:0010224 17 8 0,000 8,968E-03 0,02783972 ! protein targeting to vacuole GO:0006623 14 8 0,000 8,968E-03 0,02780439 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,968E-03 0,02776915 ! intermediate filament organization GO:0045109 12 8 0,000 8,968E-03 0,027734 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 8,968E-03 0,02769894 ! cellular extravasation GO:0045123 13 8 0,000 8,968E-03 0,02766397 ! cardiac muscle cell development GO:0055013 14 8 0,000 8,968E-03 0,02762908 ! response to antibiotic GO:0046677 11 8 0,000 8,968E-03 0,02759428 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 8,968E-03 0,02755957 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 8,968E-03 0,02752495 ! DNA topological change GO:0006265 12 8 0,000 8,968E-03 0,02749042 ! response to tropane GO:0014073 15 8 0,000 8,968E-03 0,02745597 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 8,968E-03 0,0274216 ! melanosome transport GO:0032402 13 8 0,000 8,968E-03 0,02738733 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 8,968E-03 0,02735314 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 8,968E-03 0,02731903 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,968E-03 0,02728501 ! mast cell activation GO:0045576 14 8 0,000 8,968E-03 0,02725107 ! multicellular organismal aging GO:0010259 20 8 0,000 8,968E-03 0,02721722 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 8,968E-03 0,02718345 ! gas homeostasis GO:0033483 14 8 0,000 8,968E-03 0,02714977 ! dendrite morphogenesis GO:0048813 14 8 0,000 8,968E-03 0,02711617 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 8,968E-03 0,02708265 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 8,968E-03 0,02704921 ! nucleosome disassembly GO:0006337 14 8 0,000 8,968E-03 0,02701586 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,968E-03 0,02698259 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 8,968E-03 0,0269494 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,968E-03 0,02691629 ! establishment of chromosome localization GO:0051303 14 8 0,000 8,968E-03 0,02688327 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 8,968E-03 0,02685032 ! intracellular lipid transport GO:0032365 16 8 0,000 8,968E-03 0,02681746 ! response to tumor cell GO:0002347 16 8 0,000 8,968E-03 0,02678467 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,968E-03 0,02675197 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 8,968E-03 0,02671934 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 8,968E-03 0,0266868 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,968E-03 0,02665433 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 8,968E-03 0,02662195 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 8,968E-03 0,02658964 ! hormone catabolic process GO:0042447 17 8 0,000 8,968E-03 0,02655741 ! glycolipid catabolic process GO:0019377 16 8 0,000 8,968E-03 0,02652526 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 8,968E-03 0,02649318 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 8,968E-03 0,02646119 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 8,968E-03 0,02642927 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,968E-03 0,02639742 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 8,968E-03 0,02636566 ! adult feeding behavior GO:0008343 10 8 0,000 8,968E-03 0,02633397 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 8,968E-03 0,02630236 ! ATP catabolic process GO:0006200 11 8 0,000 8,968E-03 0,02627082 ! blastocyst growth GO:0001832 19 8 0,000 8,968E-03 0,02623936 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,968E-03 0,02620797 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,968E-03 0,02617666 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 8,968E-03 0,02614542 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,968E-03 0,02611426 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 8,968E-03 0,02608317 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 8,968E-03 0,02605215 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 8,968E-03 0,02602121 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 8,968E-03 0,02599035 ! amino sugar catabolic process GO:0046348 11 8 0,000 8,968E-03 0,02595955 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 8,968E-03 0,02592883 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,968E-03 0,02589818 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 8,968E-03 0,02586761 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 8,968E-03 0,0258371 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,968E-03 0,02580667 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 8,968E-03 0,02577631 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 8,968E-03 0,02574602 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,968E-03 0,0257158 ! NAD biosynthetic process GO:0009435 17 8 0,000 8,968E-03 0,02568565 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 8,968E-03 0,02565558 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 8,968E-03 0,02562557 ! axon extension GO:0048675 16 9 0,000 0,01008395 0,02877931 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01008395 0,02874573 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01008395 0,02871222 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01008395 0,0286788 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01008395 0,02864545 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01008395 0,02861218 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01008395 0,02857899 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01008395 0,02854587 ! reproductive behavior GO:0019098 22 9 0,000 0,01008395 0,02851283 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01008395 0,02847987 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01008395 0,02844698 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01008395 0,02841417 ! UTP metabolic process GO:0046051 10 9 0,000 0,01008395 0,02838144 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01008395 0,02834878 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01008395 0,02831619 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01008395 0,02828368 ! artery development GO:0060840 25 9 0,000 0,01008395 0,02825125 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01008395 0,02821889 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01008395 0,0281866 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01008395 0,02815439 ! equilibrioception GO:0050957 20 9 0,000 0,01008395 0,02812225 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01008395 0,02809018 ! chemosensory behavior GO:0007635 21 9 0,000 0,01008395 0,02805819 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01008395 0,02802627 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01008395 0,02799442 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01008395 0,02796264 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01008395 0,02793094 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01008395 0,02789931 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01008395 0,02786775 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01008395 0,02783626 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01008395 0,02780484 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01008395 0,02777349 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01008395 0,02774222 ! protein targeting to ER GO:0045047 25 9 0,000 0,01008395 0,02771101 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01008395 0,02767987 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01008395 0,02764881 ! T cell selection GO:0045058 27 9 0,000 0,01008395 0,02761781 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01008395 0,02758688 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01008395 0,02755603 ! glycine catabolic process GO:0006546 15 9 0,000 0,01008395 0,02752524 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01008395 0,02749452 ! endosome organization GO:0007032 20 9 0,000 0,01008395 0,02746387 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01008395 0,02743328 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01008395 0,02740277 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01008395 0,02737232 ! mannose metabolic process GO:0006013 13 9 0,000 0,01008395 0,02734194 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01008395 0,02731163 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01008395 0,02728138 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01008395 0,0272512 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01008395 0,02722109 ! receptor clustering GO:0043113 20 9 0,000 0,01008395 0,02719105 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01008395 0,02716107 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01008395 0,02713115 ! retinol metabolic process GO:0042572 20 9 0,000 0,01008395 0,02710131 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01008395 0,02707152 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01008395 0,02704181 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01008395 0,02701216 ! macrophage differentiation GO:0030225 15 9 0,000 0,01008395 0,02698257 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01008395 0,02695305 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01008395 0,02692359 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01008395 0,0268942 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01008395 0,02686487 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01008395 0,02683561 ! response to amine stimulus GO:0014075 13 9 0,000 0,01008395 0,02680641 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01008395 0,02677727 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01008395 0,02674819 ! erythrocyte development GO:0048821 17 9 0,000 0,01008395 0,02671918 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01008395 0,02669024 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01008395 0,02666135 ! renal water homeostasis GO:0003091 15 9 0,000 0,01008395 0,02663253 ! postreplication repair GO:0006301 25 9 0,000 0,01008395 0,02660377 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01008395 0,02657507 ! icosanoid secretion GO:0032309 15 9 0,000 0,01008395 0,02654643 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01008395 0,02651785 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01008395 0,02648934 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01008395 0,02646089 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01008395 0,0264325 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01008395 0,02640417 ! sterol catabolic process GO:0016127 14 9 0,000 0,01008395 0,0263759 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01008395 0,02634769 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01008395 0,02631954 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01008395 0,02629145 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01008395 0,02626342 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01008395 0,02623545 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01008395 0,02620754 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01008395 0,02617969 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01008395 0,0261519 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01008395 0,02612416 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01008395 0,02609649 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01008395 0,02606888 ! purine base metabolic process GO:0006144 25 9 0,000 0,01008395 0,02604132 ! pigment granule transport GO:0051904 17 9 0,000 0,01008395 0,02601382 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01008395 0,02598638 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01008395 0,025959 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01008395 0,02593167 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01008395 0,0259044 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01008395 0,02587719 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01008395 0,02585004 ! mitochondrion localization GO:0051646 18 9 0,000 0,01008395 0,02582294 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01119825 0,02864641 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01119825 0,02861644 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01119825 0,02858654 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01119825 0,0285567 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01119825 0,02852693 ! associative learning GO:0008306 21 10 0,000 0,01119825 0,02849721 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01119825 0,02846756 ! phosphate transport GO:0006817 24 10 0,000 0,01119825 0,02843796 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01119825 0,02840843 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01119825 0,02837896 ! CTP metabolic process GO:0046036 11 10 0,000 0,01119825 0,02834956 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01119825 0,02832021 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01119825 0,02829092 ! GTP metabolic process GO:0046039 11 10 0,000 0,01119825 0,0282617 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01119825 0,02823253 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01119825 0,02820342 ! social behavior GO:0035176 29 10 0,000 0,01119825 0,02817438 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01119825 0,02814539 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01119825 0,02811647 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01119825 0,0280876 ! androgen metabolic process GO:0008209 17 10 0,000 0,01119825 0,02805879 ! phospholipid efflux GO:0033700 19 10 0,000 0,01119825 0,02803004 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01119825 0,02800135 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01119825 0,02797272 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01119825 0,02794415 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01119825 0,02791563 ! lung alveolus development GO:0048286 26 10 0,000 0,01119825 0,02788718 ! pathogenesis GO:0009405 17 10 0,000 0,01119825 0,02785878 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01119825 0,02783044 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01119825 0,02780216 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01119825 0,02777393 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01119825 0,02774576 ! endoderm development GO:0007492 18 10 0,000 0,01119825 0,02771765 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01119825 0,0276896 ! arginine catabolic process GO:0006527 17 10 0,000 0,01119825 0,0276616 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01119825 0,02763366 ! proline metabolic process GO:0006560 13 10 0,000 0,01119825 0,02760577 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01119825 0,02757794 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01119825 0,02755017 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01119825 0,02752246 ! V(D)J recombination GO:0033151 34 10 0,000 0,01119825 0,0274948 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01119825 0,02746719 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01119825 0,02743964 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01119825 0,02741215 ! B cell proliferation GO:0042100 19 10 0,000 0,01119825 0,02738471 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01119825 0,02735732 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01119825 0,02732999 ! multicellular organism growth GO:0035264 19 10 0,000 0,01119825 0,02730272 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01119825 0,02727549 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01119825 0,02724833 ! ruffle organization GO:0031529 17 10 0,000 0,01119825 0,02722122 ! epithelial cell development GO:0002064 21 10 0,000 0,01119825 0,02719416 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01119825 0,02716715 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01119825 0,0271402 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01119825 0,0271133 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01119825 0,02708646 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01119825 0,02705967 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01119825 0,02703293 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01119825 0,02700624 ! motor axon guidance GO:0008045 22 10 0,000 0,01119825 0,02697961 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01119825 0,02695303 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01119825 0,0269265 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01119825 0,02690002 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01119825 0,0268736 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01119825 0,02684722 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01119825 0,0268209 ! segment specification GO:0007379 15 10 0,000 0,01119825 0,02679463 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01119825 0,02676842 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01119825 0,02674225 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01119825 0,02671613 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01119825 0,02669007 ! response to dsRNA GO:0043331 23 10 0,000 0,01119825 0,02666406 ! DNA ligation GO:0006266 18 10 0,000 0,01119825 0,02663809 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01119825 0,02661218 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01119825 0,02658632 ! melanosome localization GO:0032400 16 10 0,000 0,01119825 0,02656051 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01119825 0,02653474 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01119825 0,02650903 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01119825 0,02648337 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01119825 0,02645776 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01119825 0,02643219 ! induction of an organ GO:0001759 17 10 0,000 0,01119825 0,02640668 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01119825 0,02638122 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01119825 0,0263558 ! protein sumoylation GO:0016925 17 10 0,000 0,01119825 0,02633043 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01119825 0,02630512 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01119825 0,02627985 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01119825 0,02625463 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01119825 0,02622945 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01119825 0,02620433 ! salivary gland development GO:0007431 28 10 0,000 0,01119825 0,02617925 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01119825 0,02615423 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01119825 0,02612925 ! midbrain development GO:0030901 14 10 0,000 0,01119825 0,02610431 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01119825 0,02607943 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01119825 0,02605459 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01119825 0,0260298 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01119825 0,02600506 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01119825 0,02598036 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01119825 0,02595571 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01119825 0,02593111 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01119825 0,02590655 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01119825 0,02588204 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01119825 0,02585758 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01119825 0,02583316 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01119825 0,02580879 ! blastocyst formation GO:0001825 18 10 0,000 0,01119825 0,02578447 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01119825 0,02576019 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01119825 0,02573596 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01119825 0,02571177 ! response to nicotine GO:0035094 20 10 0,000 0,01119825 0,02568763 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01119825 0,02566353 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01119825 0,02563948 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01231133 0,02816158 ! respiratory burst GO:0045730 17 11 0,000 0,01231133 0,02813524 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01231133 0,02810894 ! neuron fate specification GO:0048665 18 11 0,000 0,01231133 0,0280827 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01231133 0,0280565 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01231133 0,02803035 ! thyroid gland development GO:0030878 26 11 0,000 0,01231133 0,02800425 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01231133 0,0279782 ! synapsis GO:0007129 14 11 0,000 0,01231133 0,0279522 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01231133 0,02792625 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01231133 0,02790034 ! response to pain GO:0048265 27 11 0,000 0,01231133 0,02787448 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01231133 0,02784867 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01231133 0,02782291 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01231133 0,0277972 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01231133 0,02777153 ! bone resorption GO:0045453 16 11 0,000 0,01231133 0,02774591 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01231133 0,02772034 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01231133 0,02769481 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01231133 0,02766934 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01231133 0,0276439 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01231133 0,02761852 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01231133 0,02759318 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01231133 0,02756789 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01231133 0,02754264 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01231133 0,02751745 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01231133 0,02749229 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01231133 0,02746719 ! UV protection GO:0009650 20 11 0,000 0,01231133 0,02744212 ! adult heart development GO:0007512 16 11 0,000 0,01231133 0,02741711 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01231133 0,02739214 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01231133 0,02736721 ! macroautophagy GO:0016236 19 11 0,000 0,01231133 0,02734233 ! temperature homeostasis GO:0001659 18 11 0,000 0,01231133 0,0273175 ! behavioral fear response GO:0001662 27 11 0,000 0,01231133 0,02729271 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01231133 0,02726797 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01231133 0,02724327 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01231133 0,02721861 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01231133 0,027194 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01231133 0,02716944 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01231133 0,02714492 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01231133 0,02712044 ! regulation of organ growth GO:0046620 14 11 0,000 0,01231133 0,02709601 ! pigment granule localization GO:0051875 20 11 0,000 0,01231133 0,02707162 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01231133 0,02704727 ! vasoconstriction GO:0042310 20 11 0,000 0,01231133 0,02702297 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01231133 0,02699871 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01231133 0,0269745 ! embryonic axis specification GO:0000578 19 11 0,000 0,01231133 0,02695033 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01231133 0,0269262 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01231133 0,02690212 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01231133 0,02687808 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01231133 0,02685408 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01231133 0,02683012 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01231133 0,02680621 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01231133 0,02678234 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01231133 0,02675851 ! prophase GO:0051324 17 11 0,000 0,01231133 0,02673473 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01231133 0,02671098 ! nucleosome positioning GO:0016584 15 11 0,000 0,01231133 0,02668728 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01231133 0,02666362 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01231133 0,02664001 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01231133 0,02661643 ! apical protein localization GO:0045176 18 11 0,000 0,01231133 0,0265929 ! acid secretion GO:0046717 20 11 0,000 0,01231133 0,02656941 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01231133 0,02654596 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01231133 0,02652255 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01231133 0,02649918 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01231133 0,02647585 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01231133 0,02645257 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01231133 0,02642932 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01231133 0,02640612 ! cholesterol efflux GO:0033344 21 11 0,000 0,01231133 0,02638295 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01231133 0,02635983 ! oocyte development GO:0048599 20 11 0,000 0,01231133 0,02633675 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01231133 0,02631371 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01231133 0,02629071 ! embryonic gut development GO:0048566 19 11 0,000 0,01231133 0,02626774 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01231133 0,02624482 ! activation of innate immune response GO:0002218 16 11 0,000 0,01231133 0,02622194 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01231133 0,0261991 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01231133 0,0261763 ! lysogeny GO:0030069 22 11 0,000 0,01231133 0,02615354 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01231133 0,02613081 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01231133 0,02610813 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01231133 0,02608549 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01231133 0,02606288 ! nucleus localization GO:0051647 22 11 0,000 0,01231133 0,02604032 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01342318 0,0283675 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01342318 0,02834298 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01342318 0,02831851 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01342318 0,02829407 ! virus-host interaction GO:0019048 30 12 0,000 0,01342318 0,02826968 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01342318 0,02824533 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01342318 0,02822102 ! protein complex disassembly GO:0043241 28 12 0,000 0,01342318 0,02819676 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01342318 0,02817253 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01342318 0,02814835 ! hippocampus development GO:0021766 29 12 0,000 0,01342318 0,02812421 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01342318 0,02810011 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01342318 0,02807605 ! T cell proliferation GO:0042098 32 12 0,000 0,01342318 0,02805204 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01342318 0,02802806 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01342318 0,02800412 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01342318 0,02798023 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01342318 0,02795638 ! drug transport GO:0015893 16 12 0,000 0,01342318 0,02793256 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01342318 0,02790879 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01342318 0,02788506 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01342318 0,02786137 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01342318 0,02783772 ! focal adhesion formation GO:0048041 37 12 0,000 0,01342318 0,02781411 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01342318 0,02779053 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01342318 0,027767 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01342318 0,02774351 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01342318 0,02772006 ! lipid digestion GO:0044241 21 12 0,000 0,01342318 0,02769665 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01342318 0,02767327 ! entry into host cell GO:0030260 34 12 0,000 0,01342318 0,02764994 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01342318 0,02762665 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01342318 0,02760339 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01342318 0,02758018 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01342318 0,027557 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01342318 0,02753386 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01342318 0,02751076 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01342318 0,0274877 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01342318 0,02746468 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01342318 0,0274417 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01342318 0,02741875 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01342318 0,02739585 ! cranial nerve development GO:0021545 23 12 0,000 0,01342318 0,02737298 ! fucose catabolic process GO:0019317 25 12 0,000 0,01342318 0,02735015 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01342318 0,02732736 ! histone acetylation GO:0016573 27 12 0,000 0,01342318 0,0273046 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01342318 0,02728189 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01342318 0,02725921 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01342318 0,02723657 ! zymogen activation GO:0031638 18 12 0,000 0,01342318 0,02721397 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01342318 0,0271914 ! T cell homeostasis GO:0043029 28 12 0,000 0,01342318 0,02716887 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01342318 0,02714638 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01342318 0,02712393 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01342318 0,02710151 ! oocyte differentiation GO:0009994 21 12 0,000 0,01342318 0,02707913 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01342318 0,02705679 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01342318 0,02703448 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01342318 0,02701222 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01342318 0,02698998 ! defense response to fungus GO:0050832 15 12 0,000 0,01342318 0,02696779 ! developmental induction GO:0031128 22 12 0,000 0,01342318 0,02694563 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01342318 0,02692351 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01342318 0,02690142 ! response to cold GO:0009409 17 12 0,000 0,01342318 0,02687937 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01342318 0,02685735 ! localization within membrane GO:0051668 26 12 0,000 0,01342318 0,02683538 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01453382 0,02903198 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01453382 0,02900826 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01453382 0,02898458 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01453382 0,02896094 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01453382 0,02893734 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01453382 0,02891377 ! peroxisomal transport GO:0043574 28 13 0,000 0,01453382 0,02889024 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01453382 0,02886676 ! cartilage condensation GO:0001502 22 13 0,000 0,01453382 0,02884331 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01453382 0,02881989 ! organelle fusion GO:0048284 36 13 0,000 0,01453382 0,02879652 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01453382 0,02877319 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01453382 0,02874989 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01453382 0,02872663 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01453382 0,0287034 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01453382 0,02868022 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01453382 0,02865707 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01453382 0,02863396 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01453382 0,02861089 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01453382 0,02858785 ! methionine metabolic process GO:0006555 31 13 0,000 0,01453382 0,02856485 ! plasma membrane organization GO:0007009 27 13 0,000 0,01453382 0,02854189 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01453382 0,02851896 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01453382 0,02849608 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01453382 0,02847322 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01453382 0,02845041 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01453382 0,02842763 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01453382 0,02840489 ! exocrine system development GO:0035272 34 13 0,000 0,01453382 0,02838218 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01453382 0,02835951 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01453382 0,02833688 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01453382 0,02831428 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01453382 0,02829172 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01453382 0,0282692 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01453382 0,02824671 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01453382 0,02822425 ! protein homotetramerization GO:0051289 24 13 0,000 0,01453382 0,02820184 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01453382 0,02817945 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01453382 0,02815711 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01453382 0,02813479 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01453382 0,02811252 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01453382 0,02809028 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01453382 0,02806807 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01453382 0,0280459 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01453382 0,02802377 ! histone methylation GO:0016571 29 13 0,000 0,01453382 0,02800166 ! chromatin silencing GO:0006342 29 13 0,000 0,01453382 0,0279796 ! gland morphogenesis GO:0022612 31 13 0,000 0,01453382 0,02795757 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01453382 0,02793557 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01453382 0,02791361 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01453382 0,02789168 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01453382 0,02786979 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01453382 0,02784793 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01453382 0,02782611 ! spleen development GO:0048536 24 13 0,000 0,01453382 0,02780432 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01453382 0,02778256 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01453382 0,02776084 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01453382 0,02773915 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01453382 0,02771749 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01453382 0,02769587 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01453382 0,02767429 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01453382 0,02765273 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01453382 0,02763121 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01453382 0,02760973 ! insulin secretion GO:0030073 24 13 0,000 0,01453382 0,02758828 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01453382 0,02756686 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01453382 0,02754547 ! acrosome reaction GO:0007340 19 13 0,000 0,01453382 0,02752412 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01453382 0,0275028 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01453382 0,02748151 ! rRNA transcription GO:0009303 28 14 0,000 0,01564323 0,02955639 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01564323 0,02953355 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01564323 0,02951074 ! water transport GO:0006833 21 14 0,000 0,01564323 0,02948797 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01564323 0,02946524 ! non-recombinational repair GO:0000726 29 14 0,000 0,01564323 0,02944254 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01564323 0,02941987 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01564323 0,02939724 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01564323 0,02937464 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01564323 0,02935208 ! lipid localization GO:0010876 32 14 0,000 0,01564323 0,02932956 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01564323 0,02930707 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01564323 0,02928461 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01564323 0,02926218 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01564323 0,0292398 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01564323 0,02921744 ! arginine metabolic process GO:0006525 21 14 0,000 0,01564323 0,02919512 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01564323 0,02917283 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01564323 0,02915058 ! regulation of heart rate GO:0002027 25 14 0,000 0,01564323 0,02912836 ! fear response GO:0042596 34 14 0,000 0,01564323 0,02910618 ! organic alcohol transport GO:0015850 29 14 0,000 0,01564323 0,02908403 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01564323 0,02906191 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01564323 0,02903983 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01564323 0,02901778 ! bone mineralization GO:0030282 18 14 0,000 0,01564323 0,02899576 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01564323 0,02897378 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01564323 0,02895183 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01564323 0,02892991 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01564323 0,02890803 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01564323 0,02888618 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01564323 0,02886436 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01564323 0,02884258 ! ribosome assembly GO:0042255 18 14 0,000 0,01564323 0,02882082 ! cerebellum development GO:0021549 23 14 0,000 0,01564323 0,02879911 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01564323 0,02877742 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01564323 0,02875577 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01564323 0,02873415 ! response to gamma radiation GO:0010332 30 14 0,000 0,01564323 0,02871256 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01564323 0,028691 ! NADP metabolic process GO:0006739 24 14 0,000 0,01564323 0,02866948 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01564323 0,02864799 ! oxygen transport GO:0015671 22 14 0,000 0,01564323 0,02862653 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01564323 0,0286051 ! male genitalia development GO:0030539 26 14 0,000 0,01564323 0,0285837 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01564323 0,02856234 ! regulation of axon extension GO:0030516 43 14 0,000 0,01564323 0,02854101 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01564323 0,02851971 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01564323 0,02849844 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01675143 0,03049459 ! lactation GO:0007595 30 15 0,000 0,01675143 0,03047188 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01675143 0,03044921 ! reproductive cellular process GO:0048610 22 15 0,000 0,01675143 0,03042657 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01675143 0,03040397 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01675143 0,0303814 ! superoxide anion generation GO:0042554 22 15 0,000 0,01675143 0,03035886 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01675143 0,03033635 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01675143 0,03031388 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01675143 0,03029144 ! copper ion transport GO:0006825 22 15 0,000 0,01675143 0,03026904 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01675143 0,03024667 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01675143 0,03022433 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01675143 0,03020202 ! sulfate transport GO:0008272 27 15 0,000 0,01675143 0,03017975 ! response to cAMP GO:0051591 25 15 0,000 0,01675143 0,03015751 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01675143 0,0301353 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01675143 0,03011313 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01675143 0,03009099 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01675143 0,03006888 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01675143 0,0300468 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01675143 0,03002475 ! vesicle coating GO:0006901 38 15 0,000 0,01675143 0,03000274 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01675143 0,02998076 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01675143 0,02995881 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01675143 0,0299369 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01675143 0,02991501 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01675143 0,02989316 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01675143 0,02987134 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01675143 0,02984956 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01675143 0,0298278 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01675143 0,02980607 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01675143 0,02978438 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01675143 0,02976272 ! histone deacetylation GO:0016575 24 15 0,000 0,01675143 0,02974109 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01675143 0,02971949 ! water homeostasis GO:0030104 28 15 0,000 0,01675143 0,02969792 ! cofactor transport GO:0051181 30 15 0,000 0,01675143 0,02967639 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01675143 0,02965488 ! muscle maintenance GO:0046716 26 15 0,000 0,01675143 0,02963341 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01675143 0,02961197 ! intestinal absorption GO:0050892 31 15 0,000 0,01675143 0,02959056 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01675143 0,02956918 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01675143 0,02954783 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01675143 0,02952651 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01675143 0,02950522 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01675143 0,02948396 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01675143 0,02946274 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01675143 0,02944154 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01675143 0,02942037 ! actin filament polymerization GO:0030041 27 15 0,000 0,01675143 0,02939924 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01675143 0,02937813 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01785841 0,03129706 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01785841 0,03127462 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01785841 0,03125222 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01785841 0,03122985 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01785841 0,03120751 ! bone remodeling GO:0046849 28 16 0,000 0,01785841 0,0311852 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01785841 0,03116293 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01785841 0,03114068 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01785841 0,03111847 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01785841 0,03109629 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01785841 0,03107414 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01785841 0,03105203 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01785841 0,03102994 ! startle response GO:0001964 28 16 0,000 0,01785841 0,03100789 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01785841 0,03098586 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01785841 0,03096387 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01785841 0,03094191 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01785841 0,03091998 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01785841 0,03089808 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01785841 0,03087622 ! pituitary gland development GO:0021983 30 16 0,000 0,01785841 0,03085438 ! response to osmotic stress GO:0006970 27 16 0,000 0,01785841 0,03083258 ! lysosomal transport GO:0007041 31 16 0,000 0,01785841 0,0308108 ! L-amino acid transport GO:0015807 33 16 0,000 0,01785841 0,03078906 ! stem cell development GO:0048864 46 16 0,000 0,01785841 0,03076735 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01785841 0,03074566 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01785841 0,03072401 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01785841 0,03070239 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01785841 0,0306808 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01785841 0,03065924 ! axon cargo transport GO:0008088 46 16 0,000 0,01785841 0,03063771 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01785841 0,03061621 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01785841 0,03059474 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01785841 0,0305733 ! DNA replication initiation GO:0006270 28 16 0,000 0,01785841 0,03055189 ! neuron recognition GO:0008038 40 16 0,000 0,01785841 0,03053051 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01785841 0,03050916 ! tissue regeneration GO:0042246 27 16 0,000 0,01785841 0,03048784 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01785841 0,03046655 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01785841 0,03044529 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01785841 0,03042406 ! biomineral formation GO:0031214 22 16 0,000 0,01785841 0,03040285 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01785841 0,03038168 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01785841 0,03036054 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01785841 0,03033943 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01785841 0,03031834 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01785841 0,03029729 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01785841 0,03027626 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01785841 0,03025527 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01785841 0,0302343 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01785841 0,03021336 ! peptide hormone processing GO:0016486 27 16 0,000 0,01785841 0,03019245 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01896418 0,03203975 ! metencephalon development GO:0022037 32 17 0,000 0,01896418 0,03201761 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01896418 0,0319955 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,01896418 0,03197342 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01896418 0,03195137 ! signal complex assembly GO:0007172 47 17 0,000 0,01896418 0,03192935 ! filopodium assembly GO:0046847 42 17 0,000 0,01896418 0,03190736 ! endothelial cell migration GO:0043542 31 17 0,000 0,01896418 0,0318854 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01896418 0,03186347 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01896418 0,03184157 ! glial cell development GO:0021782 28 17 0,000 0,01896418 0,0318197 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01896418 0,03179786 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01896418 0,03177605 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01896418 0,03175427 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01896418 0,03173252 ! myoblast differentiation GO:0045445 50 17 0,000 0,01896418 0,0317108 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01896418 0,03168911 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01896418 0,03166745 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01896418 0,03164582 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01896418 0,03162422 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01896418 0,03160265 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01896418 0,03158111 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01896418 0,03155959 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01896418 0,03153811 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01896418 0,03151666 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01896418 0,03149523 ! regulation of protein binding GO:0043393 33 17 0,000 0,01896418 0,03147383 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,01896418 0,03145247 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01896418 0,03143113 ! genitalia development GO:0048806 32 17 0,000 0,01896418 0,03140982 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01896418 0,03138854 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01896418 0,03136729 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01896418 0,03134606 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01896418 0,03132487 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01896418 0,0313037 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01896418 0,03128257 ! steroid catabolic process GO:0006706 34 17 0,000 0,01896418 0,03126146 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01896418 0,03124038 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01896418 0,03121933 ! gas transport GO:0015669 26 17 0,000 0,01896418 0,03119831 ! organic cation transport GO:0015695 32 17 0,000 0,01896418 0,03117731 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01896418 0,03115634 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01896418 0,03113541 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,01896418 0,03111449 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02006873 0,03290463 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02006873 0,03288257 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02006873 0,03286053 ! limbic system development GO:0021761 40 18 0,000 0,02006873 0,03283852 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02006873 0,03281654 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02006873 0,03279458 ! adult walking behavior GO:0007628 36 18 0,000 0,02006873 0,03277266 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02006873 0,03275077 ! heart looping GO:0001947 34 18 0,000 0,02006873 0,03272891 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02006873 0,03270707 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02006873 0,03268527 ! centrosome cycle GO:0007098 26 18 0,000 0,02006873 0,03266349 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02006873 0,03264175 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02006873 0,03262003 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02006873 0,03259834 ! glycine metabolic process GO:0006544 30 18 0,000 0,02006873 0,03257668 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02006873 0,03255505 ! response to retinoic acid GO:0032526 31 18 0,000 0,02006873 0,03253345 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02006873 0,03251187 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02006873 0,03249033 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02006873 0,03246881 ! DNA integration GO:0015074 32 18 0,000 0,02006873 0,03244732 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02006873 0,03242586 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02006873 0,03240443 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02006873 0,03238303 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02006873 0,03236165 ! neural crest cell migration GO:0001755 41 18 0,000 0,02006873 0,03234031 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02006873 0,03231899 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02006873 0,0322977 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02006873 0,03227643 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02006873 0,0322552 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02006873 0,03223399 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02006873 0,03221282 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02006873 0,03219166 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02006873 0,03217054 ! detection of bacterium GO:0016045 22 18 0,000 0,02006873 0,03214945 ! nerve development GO:0021675 34 18 0,000 0,02006873 0,03212838 ! defense response to virus GO:0051607 43 18 0,000 0,02006873 0,03210734 ! microspike assembly GO:0030035 46 18 0,000 0,02006873 0,03208632 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02006873 0,03206534 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02006873 0,03204438 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02117207 0,03378404 ! positive regulation of translation GO:0045727 31 19 0,000 0,02117207 0,03376199 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02117207 0,03373996 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02117207 0,03371797 ! neuron maturation GO:0042551 46 19 0,000 0,02117207 0,033696 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02117207 0,03367406 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02117207 0,03365216 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02117207 0,03363028 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02117207 0,03360842 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02117207 0,0335866 ! inositol metabolic process GO:0006020 33 19 0,000 0,02117207 0,0335648 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02117207 0,03354304 ! memory GO:0007613 34 19 0,000 0,02117207 0,0335213 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02117207 0,03349959 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02117207 0,03347791 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02117207 0,03345625 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02117207 0,03343462 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02117207 0,03341303 ! cerebral cortex development GO:0021987 40 19 0,000 0,02117207 0,03339145 ! pigmentation during development GO:0048066 42 19 0,000 0,02117207 0,03336991 ! response to vitamin A GO:0033189 32 19 0,000 0,02117207 0,0333484 ! heme metabolic process GO:0042168 40 19 0,000 0,02117207 0,03332691 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02117207 0,03330545 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02117207 0,03328402 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02117207 0,03326261 ! response to fungus GO:0009620 26 19 0,000 0,02117207 0,03324124 ! peptide cross-linking GO:0018149 39 19 0,000 0,02117207 0,03321989 ! protein export from nucleus GO:0006611 40 19 0,000 0,02117207 0,03319856 ! heart process GO:0003015 32 19 0,000 0,02117207 0,03317727 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02117207 0,033156 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02117207 0,03313476 ! visual learning GO:0008542 38 19 0,000 0,02117207 0,03311355 ! cellular pigmentation GO:0033059 37 19 0,000 0,02117207 0,03309236 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02117207 0,0330712 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02117207 0,03305007 ! vitamin transport GO:0051180 31 19 0,000 0,02117207 0,03302897 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02117207 0,03300789 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02117207 0,03298684 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02117207 0,03296581 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02117207 0,03294482 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02117207 0,03292385 ! cilium assembly GO:0042384 38 19 0,000 0,02117207 0,0329029 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02117207 0,03288199 ! protein secretion GO:0009306 45 20 0,000 0,0222742 0,03457171 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0222742 0,03454975 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0222742 0,03452783 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0222742 0,03450594 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,0222742 0,03448407 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,0222742 0,03446223 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0222742 0,03444042 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0222742 0,03441864 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0222742 0,03439688 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,0222742 0,03437515 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0222742 0,03435345 ! response to vitamin GO:0033273 36 20 0,000 0,0222742 0,03433178 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0222742 0,03431013 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,0222742 0,03428851 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0222742 0,03426692 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0222742 0,03424535 ! response to alkaloid GO:0043279 38 20 0,000 0,0222742 0,03422381 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0222742 0,0342023 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0222742 0,03418082 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0222742 0,03415936 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0222742 0,03413793 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,0222742 0,03411653 ! actin filament bundle formation GO:0051017 47 20 0,000 0,0222742 0,03409515 ! body fluid secretion GO:0007589 33 20 0,000 0,0222742 0,0340738 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0222742 0,03405248 ! peptide secretion GO:0002790 38 20 0,000 0,0222742 0,03403118 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0222742 0,03400991 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0222742 0,03398867 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0222742 0,03396746 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0222742 0,03394627 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0222742 0,0339251 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0222742 0,03390396 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0222742 0,03388285 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0222742 0,03386177 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0222742 0,03384071 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0222742 0,03381968 ! regulation of glucose import GO:0046324 30 20 0,000 0,0222742 0,03379867 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0222742 0,03377769 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0222742 0,03375674 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0222742 0,03373581 ! negative regulation of translation GO:0017148 32 20 0,000 0,0222742 0,03371491 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0222742 0,03369403 ! regulation of cell killing GO:0031341 46 21 0,000 0,02337512 0,0353375 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02337512 0,03531565 ! hormone secretion GO:0046879 39 21 0,000 0,02337512 0,03529382 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02337512 0,03527202 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02337512 0,03525025 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02337512 0,03522851 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02337512 0,03520679 ! ovarian follicle development GO:0001541 39 21 0,000 0,02337512 0,03518509 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02337512 0,03516343 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02337512 0,03514179 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02337512 0,03512018 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02337512 0,03509859 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02337512 0,03507703 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02337512 0,0350555 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02337512 0,03503399 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02337512 0,03501251 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02337512 0,03499106 ! sensory perception of pain GO:0019233 33 21 0,000 0,02337512 0,03496963 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02337512 0,03494823 ! diencephalon development GO:0021536 36 21 0,000 0,02337512 0,03492685 ! collagen fibril organization GO:0030199 62 21 0,000 0,02337512 0,03490551 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02337512 0,03488418 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02337512 0,03486289 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02337512 0,03484162 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02337512 0,03482037 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02337512 0,03479915 ! collagen catabolic process GO:0030574 29 21 0,000 0,02337512 0,03477796 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02337512 0,03475679 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02337512 0,03473565 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02337512 0,03471453 ! actin filament-based movement GO:0030048 47 21 0,000 0,02337512 0,03469344 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02337512 0,03467238 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02447483 0,03628155 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02447483 0,03625955 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02447483 0,03623758 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02447483 0,03621563 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02447483 0,0361937 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02447483 0,03617181 ! microtubule-based transport GO:0010970 59 22 0,000 0,02447483 0,03614994 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02447483 0,0361281 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02447483 0,03610628 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02447483 0,03608449 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02447483 0,03606273 ! cellular response to starvation GO:0009267 37 22 0,000 0,02447483 0,03604099 ! vacuolar transport GO:0007034 41 22 0,000 0,02447483 0,03601928 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02447483 0,03599759 ! fucose metabolic process GO:0006004 44 22 0,000 0,02447483 0,03597593 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02447483 0,0359543 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02447483 0,03593269 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02447483 0,03591111 ! ureteric bud development GO:0001657 50 22 0,000 0,02447483 0,03588956 ! cell aging GO:0007569 48 22 0,000 0,02447483 0,03586803 ! stem cell differentiation GO:0048863 57 22 0,000 0,02447483 0,03584652 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02447483 0,03582504 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02447483 0,03580359 ! cytolysis GO:0019835 27 22 0,000 0,02447483 0,03578217 ! renal system process GO:0003014 42 22 0,000 0,02447483 0,03576077 ! vasodilation GO:0042311 40 22 0,000 0,02447483 0,03573939 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02447483 0,03571804 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02447483 0,03569672 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02447483 0,03567542 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02447483 0,03565414 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02447483 0,0356329 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02447483 0,03561167 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02447483 0,03559048 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02447483 0,0355693 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02447483 0,03554816 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02447483 0,03552703 ! sarcomere organization GO:0045214 32 22 0,000 0,02447483 0,03550594 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02447483 0,03548487 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02447483 0,03546382 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02447483 0,0354428 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02447483 0,0354218 ! gut development GO:0048565 44 22 0,000 0,02447483 0,03540083 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02447483 0,03537988 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02447483 0,03535896 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02447483 0,03533806 ! protein stabilization GO:0050821 41 22 0,000 0,02447483 0,03531719 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02557333 0,03688054 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02557333 0,03685879 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02557333 0,03683705 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02557333 0,03681535 ! gluconeogenesis GO:0006094 38 23 0,000 0,02557333 0,03679366 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02557333 0,03677201 ! viral genome replication GO:0019079 44 23 0,000 0,02557333 0,03675038 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02557333 0,03672877 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02557333 0,03670719 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02557333 0,03668564 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02557333 0,03666411 ! regeneration GO:0031099 42 23 0,000 0,02557333 0,0366426 ! axis specification GO:0009798 43 23 0,000 0,02557333 0,03662113 ! visual behavior GO:0007632 46 23 0,000 0,02557333 0,03659967 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02557333 0,03657824 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02557333 0,03655684 ! response to ethanol GO:0045471 47 23 0,000 0,02557333 0,03653546 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02557333 0,03651411 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02557333 0,03649278 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02557333 0,03647148 ! peroxisome organization GO:0007031 43 23 0,000 0,02557333 0,0364502 ! lysosome organization GO:0007040 47 23 0,000 0,02557333 0,03642895 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02557333 0,03640772 ! vesicle targeting GO:0006903 49 23 0,000 0,02557333 0,03638651 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02557333 0,03636533 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02557333 0,03634418 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02557333 0,03632305 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02557333 0,03630194 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02557333 0,03628086 ! DNA modification GO:0006304 36 23 0,000 0,02557333 0,0362598 ! fatty acid transport GO:0015908 47 23 0,000 0,02557333 0,03623877 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02557333 0,03621776 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02557333 0,03619678 ! hormone transport GO:0009914 41 23 0,000 0,02557333 0,03617582 ! cell-cell recognition GO:0009988 28 23 0,000 0,02557333 0,03615488 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02557333 0,03613397 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02557333 0,03611309 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02557333 0,03609222 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02667062 0,03761913 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02667062 0,03759742 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02667062 0,03757574 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02667062 0,03755408 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02667062 0,03753245 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02667062 0,03751084 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02667062 0,03748926 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02667062 0,0374677 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02667062 0,03744617 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02667062 0,03742466 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02667062 0,03740318 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02667062 0,03738172 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02667062 0,03736028 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02667062 0,03733887 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02667062 0,03731749 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02667062 0,03729613 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02667062 0,03727479 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02667062 0,03725348 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02667062 0,03723219 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02667062 0,03721093 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02667062 0,03718969 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02667062 0,03716847 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02667062 0,03714728 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02667062 0,03712612 ! membrane depolarization GO:0051899 45 24 0,000 0,02667062 0,03710497 ! pallium development GO:0021543 56 24 0,000 0,02667062 0,03708386 ! oogenesis GO:0048477 44 24 0,000 0,02667062 0,03706276 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02667062 0,03704169 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02667062 0,03702065 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02667062 0,03699962 ! platelet activation GO:0030168 41 24 0,000 0,02667062 0,03697862 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02667062 0,03695765 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02667062 0,0369367 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02667062 0,03691577 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02667062 0,03689487 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02667062 0,03687399 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02667062 0,03685313 ! regulation of amine transport GO:0051952 41 24 0,000 0,02667062 0,0368323 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02667062 0,03681149 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02776672 0,0383027 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02776672 0,03828109 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02776672 0,0382595 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02776672 0,03823793 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02776672 0,03821639 ! phototransduction GO:0007602 37 25 0,000 0,02776672 0,03819487 ! keratinization GO:0031424 37 25 0,000 0,02776672 0,03817338 ! vasculogenesis GO:0001570 49 25 0,000 0,02776672 0,03815191 ! vacuole organization GO:0007033 49 25 0,000 0,02776672 0,03813046 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02776672 0,03810904 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02776672 0,03808764 ! receptor metabolic process GO:0043112 53 25 0,000 0,02776672 0,03806627 ! chromosome condensation GO:0030261 48 25 0,000 0,02776672 0,03804492 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02776672 0,03802359 ! regulation of behavior GO:0050795 48 25 0,000 0,02776672 0,03800229 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02776672 0,03798101 ! interaction with host GO:0051701 66 25 0,000 0,02776672 0,03795976 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02776672 0,03793853 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02776672 0,03791732 ! immunoglobulin production GO:0002377 62 25 0,000 0,02776672 0,03789614 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02776672 0,03787498 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02776672 0,03785384 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02776672 0,03783273 ! liver development GO:0001889 55 25 0,000 0,02776672 0,03781164 ! protein tetramerization GO:0051262 57 25 0,000 0,02776672 0,03779058 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,0288616 0,03925885 ! myelination GO:0042552 50 26 0,000 0,0288616 0,03923701 ! initiation of viral infection GO:0019059 60 26 0,000 0,0288616 0,03921518 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,0288616 0,03919339 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,0288616 0,03917161 ! molting cycle process GO:0022404 52 26 0,000 0,0288616 0,03914986 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,0288616 0,03912814 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,0288616 0,03910643 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,0288616 0,03908476 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,0288616 0,0390631 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,0288616 0,03904147 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,0288616 0,03901987 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,0288616 0,03899829 ! digestive system process GO:0022600 49 26 0,000 0,0288616 0,03897673 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,0288616 0,03895519 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,0288616 0,03893368 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,0288616 0,0389122 ! neural crest cell development GO:0014032 59 26 0,000 0,0288616 0,03889073 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,0288616 0,03886929 ! negative regulation of cell development GO:0010721 83 26 0,000 0,0288616 0,03884788 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,0288616 0,03882649 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,0288616 0,03880512 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,0288616 0,03878377 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,0288616 0,03876245 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,0288616 0,03874115 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,0288616 0,03871988 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,0288616 0,03869863 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,0288616 0,0386774 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,0288616 0,03865619 ! blastocyst development GO:0001824 50 26 0,000 0,0288616 0,03863501 ! telomere organization GO:0032200 46 26 0,000 0,0288616 0,03861386 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,0288616 0,03859272 ! neural tube closure GO:0001843 58 26 0,000 0,0288616 0,03857161 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,0288616 0,03855052 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,0288616 0,03852945 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02995529 0,03996765 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02995529 0,03994584 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02995529 0,03992404 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02995529 0,03990228 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02995529 0,03988053 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02995529 0,03985881 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02995529 0,03983711 ! iron ion transport GO:0006826 65 27 0,000 0,02995529 0,03981544 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02995529 0,03979379 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02995529 0,03977216 ! tube lumen formation GO:0035148 59 27 0,000 0,02995529 0,03975056 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02995529 0,03972898 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02995529 0,03970742 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02995529 0,03968589 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02995529 0,03966438 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02995529 0,03964289 ! response to starvation GO:0042594 47 27 0,000 0,02995529 0,03962143 ! response to toxin GO:0009636 49 27 0,000 0,02995529 0,03959999 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02995529 0,03957857 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,02995529 0,03955718 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02995529 0,0395358 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02995529 0,03951446 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02995529 0,03949313 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02995529 0,03947183 ! neuron fate commitment GO:0048663 52 28 0,000 0,03104778 0,04088933 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03104778 0,0408673 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03104778 0,0408453 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03104778 0,04082331 ! vesicle docking GO:0048278 55 28 0,000 0,03104778 0,04080135 ! circadian rhythm GO:0007623 56 28 0,000 0,03104778 0,04077942 ! dendrite development GO:0016358 67 28 0,000 0,03104778 0,0407575 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03104778 0,04073561 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03104778 0,04071375 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03104778 0,04069191 ! base-excision repair GO:0006284 41 28 0,000 0,03104778 0,04067009 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03104778 0,04064829 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03104778 0,04062652 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03104778 0,04060477 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03104778 0,04058305 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03104778 0,04056134 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03104778 0,04053967 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03104778 0,04051801 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03104778 0,04049638 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03104778 0,04047477 ! lipid oxidation GO:0034440 48 28 0,000 0,03104778 0,04045318 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03104778 0,04043162 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03104778 0,04041008 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03213906 0,04180816 ! translational initiation GO:0006413 66 29 0,000 0,03213906 0,04178591 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03213906 0,04176368 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03213906 0,04174148 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03213906 0,0417193 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03213906 0,04169715 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03213906 0,04167501 ! primary neural tube formation GO:0014020 61 29 0,000 0,03213906 0,0416529 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03213906 0,04163082 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03213906 0,04160876 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03213906 0,04158672 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03213906 0,0415647 ! somitogenesis GO:0001756 52 29 0,000 0,03213906 0,04154271 ! synaptogenesis GO:0007416 46 29 0,000 0,03213906 0,04152074 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03213906 0,0414988 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03213906 0,04147688 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03213906 0,04145498 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03213906 0,0414331 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03322915 0,04281583 ! phenol metabolic process GO:0018958 56 30 0,000 0,03322915 0,04279326 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03322915 0,04277071 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03322915 0,04274819 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03322915 0,04272569 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03322915 0,04270321 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03322915 0,04268076 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03322915 0,04265833 ! acute-phase response GO:0006953 50 30 0,000 0,03322915 0,04263593 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03322915 0,04261355 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03322915 0,04259119 ! myofibril assembly GO:0030239 50 30 0,000 0,03322915 0,04256886 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03322915 0,04254654 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03322915 0,04252426 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03322915 0,04250199 ! cell fate determination GO:0001709 64 30 0,000 0,03322915 0,04247975 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03322915 0,04245754 ! phospholipid transport GO:0015914 65 30 0,000 0,03322915 0,04243534 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03322915 0,04241317 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03322915 0,04239102 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03322915 0,0423689 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03322915 0,0423468 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03322915 0,04232472 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03322915 0,04230266 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03431804 0,04366613 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03431804 0,0436434 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03431804 0,04362069 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03431804 0,04359801 ! cell junction assembly GO:0034329 85 31 0,000 0,03431804 0,04357535 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03431804 0,04355271 ! ovulation cycle process GO:0022602 55 31 0,000 0,03431804 0,0435301 ! peptide transport GO:0015833 60 31 0,000 0,03431804 0,04350751 ! male gonad development GO:0008584 56 31 0,000 0,03431804 0,04348494 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03431804 0,0434624 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03431804 0,04343988 ! detection of light stimulus GO:0009583 44 31 0,000 0,03431804 0,04341738 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03431804 0,04339491 ! natural killer cell activation GO:0030101 50 31 0,000 0,03431804 0,04337246 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03431804 0,04335003 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03431804 0,04332763 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03431804 0,04330525 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03431804 0,04328289 ! response to heat GO:0009408 54 31 0,000 0,03431804 0,04326056 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03431804 0,04323825 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03540573 0,04458567 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03540573 0,0445627 ! collagen metabolic process GO:0032963 49 32 0,000 0,03540573 0,04453975 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03540573 0,04451683 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03540573 0,04449393 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03540573 0,04447105 ! metanephros development GO:0001656 81 32 0,000 0,03540573 0,0444482 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03540573 0,04442537 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03540573 0,04440257 ! muscle cell development GO:0055001 52 32 0,000 0,03540573 0,04437979 ! mesoderm formation GO:0001707 73 32 0,000 0,03540573 0,04435703 ! ovulation cycle GO:0042698 57 32 0,000 0,03540573 0,04433429 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03540573 0,04431158 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03540573 0,04428889 ! hindbrain development GO:0030902 65 32 0,000 0,03540573 0,04426622 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03540573 0,04424358 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03540573 0,04422096 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03540573 0,04419837 ! gene silencing GO:0016458 71 32 0,000 0,03540573 0,04417579 ! regulation of pH GO:0006885 56 33 0,000 0,03649223 0,04550818 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03649223 0,04548496 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03649223 0,04546176 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03649223 0,04543859 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03649223 0,04541545 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03649223 0,04539232 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03649223 0,04536922 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03649223 0,04534614 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03649223 0,04532309 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03649223 0,04530006 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03649223 0,04527705 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03649223 0,04525407 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03649223 0,04523111 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03649223 0,04520817 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03649223 0,04518526 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,03757754 0,04650553 ! glial cell differentiation GO:0010001 67 34 0,000 0,03757754 0,04648199 ! post-embryonic development GO:0009791 76 34 0,000 0,03757754 0,04645846 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,03757754 0,04643496 ! cholesterol transport GO:0030301 62 34 0,000 0,03757754 0,04641149 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,03757754 0,04638804 ! spliceosome assembly GO:0000245 75 34 0,000 0,03757754 0,04636461 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,03757754 0,0463412 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,03757754 0,04631782 ! formation of primary germ layer GO:0001704 76 34 0,000 0,03757754 0,04629446 ! cell fate specification GO:0001708 56 34 0,000 0,03757754 0,04627113 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,03757754 0,04624782 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,03757754 0,04622453 ! adult locomotory behavior GO:0008344 62 34 0,000 0,03757754 0,04620127 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,03757754 0,04617803 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,03866165 0,04748638 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,03866165 0,04746252 ! negative regulation of secretion GO:0051048 68 35 0,000 0,03866165 0,04743868 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,03866165 0,04741487 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,03866165 0,04739108 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,03866165 0,04736731 ! membrane docking GO:0022406 69 35 0,000 0,03866165 0,04734357 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,03866165 0,04731985 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,03866165 0,04729615 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,03866165 0,04727248 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,03866165 0,04724883 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,03866165 0,04722521 ! ceramide metabolic process GO:0006672 72 35 0,000 0,03866165 0,04720161 ! telencephalon development GO:0021537 81 35 0,000 0,03866165 0,04717803 ! sterol transport GO:0015918 63 35 0,000 0,03866165 0,04715448 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,03866165 0,04713095 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,03866165 0,04710744 ! placenta development GO:0001890 53 35 0,000 0,03866165 0,04708396 ! vesicle localization GO:0051648 70 35 0,000 0,03866165 0,0470605 ! regulation of muscle development GO:0048634 82 36 0,000 0,03974458 0,04835458 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,03974458 0,04833051 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,03974458 0,04830647 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,03974458 0,04828245 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,03974458 0,04825845 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,03974458 0,04823447 ! positive regulation of cell development GO:0010720 85 36 0,000 0,03974458 0,04821052 ! regulation of proteolysis GO:0030162 77 36 0,000 0,03974458 0,0481866 ! aerobic respiration GO:0009060 56 36 0,000 0,03974458 0,0481627 ! cytokine production GO:0001816 68 36 0,000 0,03974458 0,04813882 ! embryonic organ development GO:0048568 67 36 0,000 0,03974458 0,04811496 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,03974458 0,04809113 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04082631 0,04937558 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04082631 0,04935115 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04082631 0,04932674 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04082631 0,04930236 ! odontogenesis GO:0042476 74 37 0,000 0,04082631 0,049278 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04082631 0,04925367 ! tissue remodeling GO:0048771 78 37 0,000 0,04082631 0,04922936 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04082631 0,04920507 ! female gonad development GO:0008585 71 37 0,000 0,04082631 0,04918081 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04082631 0,04915657 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04082631 0,04913235 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,04082631 0,04910816 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04082631 0,04908399 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,04190686 0,05035831 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04190686 0,05033355 ! meiosis I GO:0007127 74 38 0,000 0,04190686 0,05030882 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04190686 0,05028411 ! organic anion transport GO:0015711 82 38 0,000 0,04190686 0,05025942 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04190686 0,05023476 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04190686 0,05021013 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04190686 0,05018551 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04190686 0,05016092 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04190686 0,05013636 ! regulation of protein stability GO:0031647 77 38 0,000 0,04190686 0,05011182 ! spermatid development GO:0007286 69 38 0,000 0,04190686 0,0500873 ! pigment metabolic process GO:0042440 87 38 0,000 0,04190686 0,05006281 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,04190686 0,05003834 ! neural tube formation GO:0001841 79 38 0,000 0,04190686 0,0500139 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04298621 0,05127701 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04298621 0,05125199 ! negative regulation of binding GO:0051100 71 39 0,000 0,04298621 0,05122699 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04298621 0,05120201 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04298621 0,05117706 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04298621 0,05115213 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04298621 0,05112723 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04298621 0,05110235 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04298621 0,05107749 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04298621 0,05105266 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04406439 0,05230773 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04406439 0,05228232 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04406439 0,05225694 ! learning GO:0007612 82 40 0,000 0,04406439 0,05223159 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04406439 0,05220626 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04406439 0,05218095 ! lipid homeostasis GO:0055088 75 40 0,000 0,04406439 0,05215567 ! mismatch repair GO:0006298 58 40 0,000 0,04406439 0,05213041 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04406439 0,05210518 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04406439 0,05207997 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04406439 0,05205479 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04514138 0,0533013 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04514138 0,05327555 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04514138 0,05324982 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04514138 0,05322412 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04514138 0,05319845 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04514138 0,0531728 ! gliogenesis GO:0042063 91 41 0,000 0,04514138 0,05314717 ! feeding behavior GO:0007631 69 41 0,000 0,04514138 0,05312157 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04514138 0,053096 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04514138 0,05307044 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04514138 0,05304492 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04514138 0,05301942 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04514138 0,05299394 ! spermatid differentiation GO:0048515 73 41 0,000 0,04514138 0,05296848 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04514138 0,05294306 ! RNA modification GO:0009451 64 41 0,000 0,04514138 0,05291765 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04621718 0,0541528 ! ear morphogenesis GO:0042471 64 42 0,000 0,04621718 0,05412684 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04621718 0,0541009 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,04621718 0,05407499 ! T cell differentiation GO:0030217 93 42 0,000 0,04621718 0,0540491 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04621718 0,05402324 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04621718 0,05399741 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04621718 0,0539716 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04621718 0,05394581 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04621718 0,05392005 ! cytokinesis GO:0000910 84 42 0,000 0,04621718 0,05389431 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04621718 0,0538686 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,04729181 0,05509484 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,04729181 0,05506858 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,04729181 0,05504235 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,04729181 0,05501614 ! regulation of tube size GO:0035150 76 43 0,000 0,04729181 0,05498995 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,04729181 0,05496379 ! glucose transport GO:0015758 66 43 0,000 0,04729181 0,05493765 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,04729181 0,05491154 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,04729181 0,05488546 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,04729181 0,0548594 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,04729181 0,05483336 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,04729181 0,05480735 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,04729181 0,05478136 ! segmentation GO:0035282 78 43 0,000 0,04729181 0,0547554 ! ion transmembrane transport GO:0034220 79 43 0,000 0,04729181 0,05472946 ! neuron migration GO:0001764 85 43 0,000 0,04729181 0,05470354 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,04729181 0,05467766 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,04836525 0,05589229 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,04836525 0,05586587 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,04836525 0,05583947 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,04836525 0,05581309 ! hexose transport GO:0008645 68 44 0,000 0,04836525 0,05578674 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,04836525 0,05576041 ! striated muscle contraction GO:0006941 85 44 0,000 0,04836525 0,05573411 ! phagocytosis GO:0006909 105 44 0,000 0,04836525 0,05570783 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,04836525 0,05568158 ! double-strand break repair GO:0006302 85 44 0,000 0,04836525 0,05565535 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,04943752 0,05686245 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,04943752 0,05683569 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,04943752 0,05680896 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,04943752 0,05678225 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,04943752 0,05675557 ! B cell differentiation GO:0030183 124 45 0,000 0,04943752 0,05672891 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,04943752 0,05670228 ! female gamete generation GO:0007292 71 45 0,000 0,04943752 0,05667567 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,04943752 0,05664909 ! developmental growth GO:0048589 88 45 0,000 0,04943752 0,05662253 ! maintenance of location in cell GO:0051651 101 45 0,000 0,04943752 0,05659599 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,0505086 0,05779509 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,0505086 0,05776803 ! glycolysis GO:0006096 71 46 0,000 0,0505086 0,057741 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,0505086 0,05771399 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,0505086 0,05768701 ! leukocyte migration GO:0050900 75 46 0,000 0,0505086 0,05766005 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,0505086 0,05763312 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,0505086 0,05760622 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,0505086 0,05757934 ! pigmentation GO:0043473 103 46 0,000 0,0505086 0,05755248 ! cell growth GO:0016049 90 46 0,000 0,0505086 0,05752565 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,0505086 0,05749884 ! neural tube development GO:0021915 91 47 0,000 0,05157851 0,05868948 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05157851 0,05866215 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05157851 0,05863486 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05264725 0,05982196 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05264725 0,05979415 ! mitochondrial transport GO:0006839 94 48 0,000 0,05264725 0,05976637 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05264725 0,05973861 ! cellular component disassembly GO:0022411 89 48 0,000 0,05264725 0,05971087 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05264725 0,05968317 ! endosome transport GO:0016197 127 48 0,000 0,05264725 0,05965548 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05264725 0,05962783 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05264725 0,0596002 ! male sex differentiation GO:0046661 93 48 0,000 0,05264725 0,05957259 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05264725 0,05954501 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05264725 0,05951746 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05264725 0,05948993 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05264725 0,05946242 ! methylation GO:0032259 97 48 0,000 0,05264725 0,05943495 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05371481 0,06061213 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05371481 0,06058415 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05371481 0,06055619 ! JNK cascade GO:0007254 106 49 0,000 0,05371481 0,06052826 ! protein homooligomerization GO:0051260 84 49 0,000 0,05371481 0,06050036 ! regulation of action potential GO:0001508 102 50 0,000 0,05478119 0,06167302 ! regulation of ion transport GO:0043269 86 50 0,000 0,05478119 0,06164461 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05478119 0,06161623 ! endocrine system development GO:0035270 109 50 0,000 0,05478119 0,06158788 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05478119 0,06155955 ! activation of caspase activity GO:0006919 95 50 0,000 0,05478119 0,06153124 ! regulation of ossification GO:0030278 123 50 0,000 0,05478119 0,06150297 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05478119 0,06147472 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05478119 0,06144649 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05478119 0,06141829 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05478119 0,06139012 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05584641 0,06255515 ! viral infectious cycle GO:0019058 104 51 0,000 0,05584641 0,06252648 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,05584641 0,06249784 ! peptide metabolic process GO:0006518 80 51 0,000 0,05584641 0,06246922 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05584641 0,06244063 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05584641 0,06241207 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05584641 0,06238353 ! positive regulation of binding GO:0051099 88 52 0,000 0,05691045 0,06354307 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,05691045 0,06351404 ! Notch signaling pathway GO:0007219 111 52 0,000 0,05691045 0,06348504 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,05691045 0,06345606 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,05691045 0,06342712 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,05691045 0,06339819 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,05691045 0,0633693 ! excretion GO:0007588 87 52 0,000 0,05691045 0,06334043 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,05691045 0,06331158 ! histone modification GO:0016570 104 52 0,000 0,05691045 0,06328277 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,05691045 0,06325398 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,05691045 0,06322521 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,05691045 0,06319647 ! amino acid activation GO:0043038 98 52 0,000 0,05691045 0,06316776 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,05797333 0,06431828 ! inner ear development GO:0048839 89 53 0,000 0,05797333 0,06428908 ! chromatin remodeling GO:0006338 122 53 0,000 0,05797333 0,06425991 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,05797333 0,06423077 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,05797333 0,06420165 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,05797333 0,06417256 ! cartilage development GO:0051216 99 53 0,000 0,05797333 0,0641435 ! synapse organization GO:0050808 102 53 0,000 0,05797333 0,06411446 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,05903504 0,06525909 ! regulation of translational initiation GO:0006446 87 54 0,000 0,05903504 0,06522958 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,05903504 0,06520009 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,05903504 0,06517063 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,05903504 0,06514119 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,05903504 0,06511178 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,05903504 0,0650824 ! membrane fusion GO:0006944 122 54 0,000 0,05903504 0,06505304 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,05903504 0,06502371 ! covalent chromatin modification GO:0016569 115 54 0,000 0,05903504 0,06499441 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,05903504 0,06496513 ! regulation of cell shape GO:0008360 142 54 0,000 0,05903504 0,06493588 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,05903504 0,06490666 ! RNA catabolic process GO:0006401 103 55 0,000 0,06009558 0,06604296 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06009558 0,06601326 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06009558 0,06598359 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06009558 0,06595395 ! cell recognition GO:0008037 98 55 0,000 0,06009558 0,06592434 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06009558 0,06589475 ! cell maturation GO:0048469 107 55 0,000 0,06009558 0,06586518 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06009558 0,06583565 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,06009558 0,06580614 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06115495 0,06693618 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,06115495 0,0669062 ! glucose catabolic process GO:0006007 88 56 0,000 0,06115495 0,06687625 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06115495 0,06684633 ! regulation of DNA replication GO:0006275 105 56 0,000 0,06115495 0,06681644 ! RNA elongation GO:0006354 90 56 0,000 0,06115495 0,06678657 ! chloride transport GO:0006821 102 57 0,000 0,06221316 0,06791187 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06221316 0,06788154 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,06221316 0,06785123 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,06221316 0,06782096 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06221316 0,06779071 ! heart morphogenesis GO:0003007 105 57 0,000 0,06221316 0,06776048 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06221316 0,06773029 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,06221316 0,06770012 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06327021 0,06881974 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06327021 0,06878911 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06327021 0,06875851 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06327021 0,06872794 ! aging GO:0007568 112 58 0,000 0,06327021 0,06869739 ! gastrulation GO:0007369 122 58 0,000 0,06327021 0,06866687 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06327021 0,06863638 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06327021 0,06860592 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06327021 0,06857548 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06327021 0,06854507 ! maintenance of location GO:0051235 124 58 0,000 0,06327021 0,06851469 ! nuclear export GO:0051168 110 59 0,000 0,0643261 0,06962723 ! establishment of organelle localization GO:0051656 122 59 0,000 0,0643261 0,0695964 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,06538083 0,07070622 ! lipid modification GO:0030258 112 60 0,000 0,06538083 0,07067494 ! DNA catabolic process GO:0006308 94 60 0,000 0,06538083 0,07064368 ! regulation of endocytosis GO:0030100 104 60 0,000 0,06538083 0,07061245 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,06538083 0,07058124 ! adult behavior GO:0030534 104 60 0,000 0,06538083 0,07055007 ! kidney development GO:0001822 133 60 0,000 0,06538083 0,07051892 ! positive regulation of secretion GO:0051047 110 61 0,000 0,06643439 0,07162366 ! regulation of cellular component size GO:0032535 125 61 0,000 0,06643439 0,07159207 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,06643439 0,0715605 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,06643439 0,07152896 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,06643439 0,07149745 ! regulation of heart contraction GO:0008016 123 61 0,000 0,06643439 0,07146597 ! camera-type eye development GO:0043010 126 61 0,000 0,06643439 0,07143452 ! proton transport GO:0015992 117 61 0,000 0,06643439 0,07140309 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,06643439 0,07137169 ! viral reproductive process GO:0022415 132 62 0,000 0,0674868 0,07247044 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,0674868 0,0724386 ! tRNA processing GO:0008033 102 62 0,000 0,0674868 0,07240679 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,0674868 0,072375 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,06853805 0,07347015 ! regulation of mitosis GO:0007088 112 63 0,000 0,06853805 0,07343792 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,06853805 0,07340573 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,06853805 0,07337356 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,06853805 0,07334142 ! hydrogen transport GO:0006818 121 64 0,000 0,06958815 0,07443251 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,06958815 0,07439993 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,06958815 0,07436739 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,06958815 0,07433487 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,06958815 0,07430238 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07063709 0,07538944 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07063709 0,07535651 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07063709 0,07532362 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07063709 0,07529076 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,07063709 0,07525792 ! ear development GO:0043583 114 66 0,000 0,07168488 0,07634096 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,07168488 0,0763077 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,07168488 0,07627446 ! gonad development GO:0008406 115 66 0,000 0,07168488 0,07624126 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,07168488 0,07620808 ! activation of MAPK activity GO:0000187 124 67 0,000 0,07273152 0,07728713 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07273152 0,07725352 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,07273152 0,07721995 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07273152 0,0771864 ! secondary metabolic process GO:0019748 125 67 0,000 0,07273152 0,07715289 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07273152 0,0771194 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,07377701 0,07819402 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07377701 0,07816012 ! hexose catabolic process GO:0019320 113 68 0,000 0,07377701 0,07812624 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07377701 0,07809239 ! detection of external stimulus GO:0009581 102 68 0,000 0,07377701 0,07805856 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07377701 0,07802477 ! viral reproduction GO:0016032 142 68 0,000 0,07377701 0,07799101 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07377701 0,07795728 ! adaptive immune response GO:0002250 126 68 0,000 0,07377701 0,07792357 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,07377701 0,0778899 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,07482134 0,07895833 ! lung development GO:0030324 165 69 0,000 0,07482134 0,07892424 ! urogenital system development GO:0001655 149 69 0,000 0,07482134 0,07889018 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,07482134 0,07885614 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,07482134 0,07882214 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,07482134 0,07878816 ! developmental maturation GO:0021700 128 69 0,000 0,07482134 0,07875422 ! single fertilization GO:0007338 83 69 0,000 0,07482134 0,0787203 ! cell redox homeostasis GO:0045454 114 70 0,000 0,07586453 0,07978349 ! germ cell development GO:0007281 133 70 0,000 0,07586453 0,07974916 ! activation of immune response GO:0002253 120 70 0,000 0,07586453 0,07971486 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,07586453 0,07968059 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,07690658 0,08074034 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,07690658 0,08070565 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,07690658 0,080671 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,07690658 0,08063638 ! appendage morphogenesis GO:0035107 150 72 0,000 0,07794747 0,0816927 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,07794747 0,08165767 ! respiratory tube development GO:0030323 171 72 0,000 0,07794747 0,08162266 ! B cell activation GO:0042113 179 72 0,000 0,07794747 0,08158769 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,07794747 0,08155275 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,07794747 0,08151784 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,07794747 0,08148296 ! appendage development GO:0048736 151 73 0,000 0,07898723 0,08253456 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,07898723 0,08249927 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,07898723 0,08246401 ! regulation of immune effector process GO:0002697 156 73 0,000 0,07898723 0,08242879 ! acute inflammatory response GO:0002526 118 74 0,000 0,08002583 0,08347699 ! amino acid transport GO:0006865 148 74 0,000 0,08002583 0,08344136 ! respiratory system development GO:0060541 175 74 0,000 0,08002583 0,08340577 ! organelle localization GO:0051640 155 74 0,000 0,08002583 0,0833702 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,0810633 0,08441502 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,0810633 0,08437906 ! reproductive structure development GO:0048608 131 75 0,000 0,0810633 0,08434312 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,0810633 0,08430721 ! axon guidance GO:0007411 162 75 0,000 0,0810633 0,08427134 ! rhythmic process GO:0048511 142 75 0,000 0,0810633 0,08423549 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,08209963 0,0852761 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,08209963 0,08523986 ! learning or memory GO:0007611 161 76 0,000 0,08209963 0,08520365 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,08209963 0,08516747 ! regulation of blood pressure GO:0008217 134 76 0,000 0,08209963 0,08513132 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,08209963 0,0850952 ! amine catabolic process GO:0009310 136 77 0,000 0,08313482 0,08613162 ! neurotransmitter transport GO:0006836 142 77 0,000 0,08313482 0,08609511 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,08313482 0,08605862 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,08313482 0,08602217 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,08313482 0,08598576 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,08313482 0,08594937 ! regulation of catabolic process GO:0009894 173 77 0,000 0,08313482 0,08591301 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,08416886 0,08694484 ! antigen processing and presentation GO:0019882 117 78 0,000 0,08416886 0,08690809 ! fertilization GO:0009566 99 78 0,000 0,08416886 0,08687137 ! blood coagulation GO:0007596 151 79 0,000 0,08520178 0,08790031 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,08520178 0,08786321 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,08520178 0,08782613 ! protein oligomerization GO:0051259 149 79 0,000 0,08520178 0,08778909 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,08520178 0,08775208 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,08623355 0,08877731 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,08623355 0,08873992 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,08623355 0,08870255 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,08623355 0,08866522 ! meiosis GO:0007126 143 81 0,000 0,08726419 0,08968718 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,08726419 0,08964946 ! response to hypoxia GO:0001666 178 81 0,000 0,08726419 0,08961178 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,08726419 0,08957413 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,0882937 0,09059282 ! protein import into nucleus GO:0006606 174 82 0,000 0,0882937 0,09055479 ! meiotic cell cycle GO:0051321 144 82 0,000 0,0882937 0,09051679 ! exocytosis GO:0006887 153 83 0,000 0,08932208 0,09153265 ! response to drug GO:0042493 149 83 0,000 0,08932208 0,09149427 ! response to oxygen levels GO:0070482 183 83 0,000 0,08932208 0,09145592 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,08932208 0,09141761 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,08932208 0,09137933 ! nuclear import GO:0051170 177 83 0,000 0,08932208 0,09134108 ! inorganic anion transport GO:0015698 156 83 0,000 0,08932208 0,09130286 ! T cell activation GO:0042110 189 84 0,000 0,09034932 0,09231426 ! response to nutrient GO:0007584 135 84 0,000 0,09034932 0,09227566 ! digestion GO:0007586 130 84 0,000 0,09034932 0,0922371 ! hemostasis GO:0007599 165 85 0,000 0,09137544 0,09324569 ! negative regulation of transport GO:0051051 164 85 0,000 0,09137544 0,09320676 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,09137544 0,09316786 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,09137544 0,09312899 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,09137544 0,09309015 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,09137544 0,09305135 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,09342428 0,09509813 ! nucleosome assembly GO:0006334 126 87 0,000 0,09342428 0,09505852 ! regulation of protein transport GO:0051223 165 87 0,000 0,09342428 0,09501895 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,09444701 0,09601916 ! sensory perception of smell GO:0007608 117 88 0,000 0,09444701 0,09597922 ! chromatin assembly GO:0031497 128 88 0,000 0,09444701 0,09593931 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,09444701 0,09589944 ! regulation of DNA binding GO:0051101 167 89 0,000 0,09546862 0,09689649 ! tube morphogenesis GO:0035239 194 89 0,000 0,09546862 0,09685625 ! cellular defense response GO:0006968 123 89 0,000 0,09546862 0,09681604 ! protein localization in nucleus GO:0034504 192 89 0,000 0,09546862 0,09677587 ! regulation of neurological system process GO:0031644 175 89 0,000 0,09546862 0,09673573 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,0964891 0,09772922 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,0964891 0,09768872 ! gland development GO:0048732 220 91 0,000 0,09750847 0,09867986 ! defense response to bacterium GO:0042742 112 91 0,000 0,09750847 0,098639 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,09852671 0,09962779 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,09852671 0,09958657 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,09954383 0,10057302 ! amine transport GO:0015837 181 93 0,000 0,09954383 0,10053144 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,09954383 0,1004899 ! vitamin metabolic process GO:0006766 153 93 0,000 0,09954383 0,1004484 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,10055983 0,10143173 ! female pregnancy GO:0007565 166 94 0,000 0,10055983 0,10138987 ! sterol metabolic process GO:0016125 166 94 0,000 0,10055983 0,10134804 ! regulation of membrane potential GO:0042391 179 94 0,000 0,10055983 0,10130625 ! regulation of defense response GO:0031347 171 95 0,000 0,10157471 0,10228649 ! nucleosome organization GO:0034728 143 95 0,000 0,10157471 0,10224434 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,10157471 0,10220223 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,10157471 0,10216015 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,10157471 0,10211811 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,10157471 0,10207611 ! sex differentiation GO:0007548 171 96 0,000 0,10258848 0,10305249 ! regulation of T cell activation GO:0050863 175 96 0,000 0,10258848 0,10301013 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,10360113 0,1039842 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,10360113 0,1039415 ! transcription initiation GO:0006352 171 97 0,000 0,10360113 0,10389883 ! regulation of protein localization GO:0032880 188 97 0,000 0,10360113 0,1038562 ! leukocyte differentiation GO:0002521 232 98 0,000 0,10461266 0,10482721 ! forebrain development GO:0030900 210 98 0,000 0,10461266 0,10478423 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,1066324 0,10676351 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,1066324 0,10671977 ! positive regulation of immune response GO:0050778 175 100 0,000 0,1066324 0,10667607 ! hormone metabolic process GO:0042445 171 100 0,000 0,1066324 0,1066324