pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5329-6-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! MutLalpha complex binding GO:0032405 6 5 2,000 1,274E-08 4,549E-05 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 3,000 1,511E-08 2,698E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 7,119E-08 8,474E-05 ! mismatch repair complex binding GO:0032404 11 10 2,000 1,523E-07 1,36E-04 ! ADP binding GO:0043531 11 11 2,000 2,093E-07 1,495E-04 ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 2,000 2,093E-07 1,246E-04 ! response to UV GO:0009411 50 49 3,000 2,489E-07 1,27E-04 ! phosphoinositide-mediated signaling GO:0048015 79 75 3,000 1,402E-06 6,256E-04 ! protein binding, bridging GO:0030674 86 81 3,000 1,91E-06 7,58E-04 ! meiosis I GO:0007127 31 31 2,000 5,621E-06 2,007E-03 ! skeletal myofibril assembly GO:0014866 5 5 1,000 1,25E-05 4,059E-03 ! ribonuclease H activity GO:0004523 5 5 1,000 1,25E-05 3,721E-03 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 1,000 1,25E-05 3,435E-03 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 1,000 1,25E-05 3,19E-03 ! 5'-3' exonuclease activity GO:0008409 5 5 1,000 1,25E-05 2,977E-03 ! damaged DNA binding GO:0003684 42 42 2,000 1,424E-05 3,179E-03 ! SH3/SH2 adaptor activity GO:0005070 48 45 2,000 1,757E-05 3,691E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,874E-05 3,719E-03 ! regulation of helicase activity GO:0051095 6 6 1,000 1,874E-05 3,523E-03 ! insulin receptor substrate binding GO:0043560 7 6 1,000 1,874E-05 3,347E-03 ! negative regulation of DNA recombination GO:0045910 6 6 1,000 1,874E-05 3,187E-03 ! DNA replication factor C complex GO:0005663 6 6 1,000 1,874E-05 3,043E-03 ! exodeoxyribonuclease activity GO:0004529 6 6 1,000 1,874E-05 2,91E-03 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! determination of adult lifespan GO:0008340 6 6 1,000 1,874E-05 2,789E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 2,000 2,418E-05 3,454E-03 ! DNA insertion or deletion binding GO:0032135 7 7 1,000 2,622E-05 3,602E-03 GO:0032138|single base insertion or deletion binding, ! attachment of GPI anchor to protein GO:0016255 8 7 1,000 2,622E-05 3,468E-03 ! double-stranded DNA binding GO:0003690 55 54 2,000 3,051E-05 3,892E-03 ! DNA secondary structure binding GO:0000217 8 8 1,000 3,494E-05 4,303E-03 ! multicellular organismal aging GO:0010259 8 8 1,000 3,494E-05 4,159E-03 ! epidermal growth factor receptor binding GO:0005154 9 8 1,000 3,494E-05 4,025E-03 ! molecular adaptor activity GO:0060090 65 59 2,000 3,985E-05 4,447E-03 ! mismatch repair complex GO:0032300 9 9 1,000 4,489E-05 4,858E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 1,000 4,489E-05 4,715E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! DNA N-glycosylase activity GO:0019104 9 9 1,000 4,489E-05 4,581E-03 ! protein kinase regulator activity GO:0019887 64 64 2,000 5,089E-05 5,048E-03 ! immunoglobulin production during immune response GO:0002381 10 10 1,000 5,608E-05 5,413E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 1,000 5,608E-05 5,27E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! UV protection GO:0009650 11 11 1,000 6,85E-05 6,272E-03 ! meiosis GO:0007126 73 72 2,000 7,244E-05 6,467E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 75 73 2,000 7,549E-05 6,575E-03 ! kinase regulator activity GO:0019207 77 77 2,000 8,853E-05 7,527E-03 ! regulation of DNA metabolic process GO:0051052 90 80 2,000 9,922E-05 8,24E-03 ! striated muscle thin filament GO:0005865 15 14 1,000 1,131E-04 9,179E-03 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 1,000 1,131E-04 8,975E-03 ! mismatched DNA binding GO:0030983 15 15 1,000 1,304E-04 0,01012385 ! cornified envelope GO:0001533 18 16 1,000 1,489E-04 0,01131625 ! structure-specific DNA binding GO:0043566 93 92 2,000 1,504E-04 0,01118633 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 1,000 1,687E-04 0,01229327 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 1,000 1,687E-04 0,0120474 ! actin filament bundle GO:0032432 17 17 1,000 1,687E-04 0,01181118 GO:0001725|stress fiber, ! endodeoxyribonuclease activity GO:0004520 17 17 1,000 1,687E-04 0,01158404 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 1,000 1,687E-04 0,01136547 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 1,000 1,687E-04 0,011155 ! peptide cross-linking GO:0018149 20 18 1,000 1,896E-04 0,01231285 ! regulation of DNA recombination GO:0000018 22 18 1,000 1,896E-04 0,01209298 ! cellular response to unfolded protein GO:0034620 21 19 1,000 2,118E-04 0,01326955 GO:0030968|endoplasmic reticulum unfolded protein response, ! myofibril assembly GO:0030239 19 19 1,000 2,118E-04 0,01304077 GO:0055002|striated muscle cell development, ! myosin binding GO:0017022 19 19 1,000 2,118E-04 0,01281974 ! mismatch repair GO:0006298 19 19 1,000 2,118E-04 0,01260607 ! actomyosin GO:0042641 20 20 1,000 2,352E-04 0,01376778 ! nuclear inner membrane GO:0005637 20 20 1,000 2,352E-04 0,01354572 ! somatic diversification of immunoglobulins GO:0016445 20 20 1,000 2,352E-04 0,01333071 ! muscle cell development GO:0055001 21 21 1,000 2,598E-04 0,01449389 ! base-excision repair GO:0006284 21 21 1,000 2,598E-04 0,01427091 ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 1,000 2,855E-04 0,01544966 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 1,000 2,855E-04 0,01521907 GO:0016444|somatic cell DNA recombination, ! insulin receptor signaling pathway GO:0008286 28 23 1,000 3,125E-04 0,01641224 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 3,407E-04 0,01763281 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 1,000 3,407E-04 0,01738091 ! immunoglobulin production GO:0002377 28 24 1,000 3,407E-04 0,01713611 GO:0002440|production of molecular mediator of immune response, ! somatic diversification of immune receptors GO:0002200 24 24 1,000 3,407E-04 0,01689811 ! actin filament GO:0005884 28 25 1,000 3,701E-04 0,01810361 ! keratinization GO:0031424 26 25 1,000 3,701E-04 0,01785897 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 1,000 4,007E-04 0,01907631 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 1,000 4,007E-04 0,0188253 ! fat cell differentiation GO:0045444 26 26 1,000 4,007E-04 0,01858082 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 4,007E-04 0,0183426 ! actomyosin structure organization GO:0031032 28 27 1,000 4,324E-04 0,01954598 ! nuclear chromatin GO:0000790 28 27 1,000 4,324E-04 0,01930166 ! deoxyribonuclease activity GO:0004536 28 28 1,000 4,654E-04 0,02051586 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 4,654E-04 0,02026566 ! spindle organization GO:0007051 30 29 1,000 4,995E-04 0,02148999 ! negative regulation of DNA metabolic process GO:0051053 34 30 1,000 5,348E-04 0,02273545 ! GPI anchor biosynthetic process GO:0006506 32 30 1,000 5,348E-04 0,02246798 ! striated muscle cell differentiation GO:0051146 31 31 1,000 5,713E-04 0,02372212 ! GPI anchor metabolic process GO:0006505 33 31 1,000 5,713E-04 0,02344945 ! replication fork GO:0005657 32 31 1,000 5,713E-04 0,02318298 ! JAK-STAT cascade GO:0007259 34 32 1,000 6,09E-04 0,02443408 ! cellular response to insulin stimulus GO:0032869 37 32 1,000 6,09E-04 0,02416259 ! endoribonuclease activity GO:0004521 34 33 1,000 6,478E-04 0,02542157 ! response to calcium ion GO:0051592 39 35 1,000 7,29E-04 0,02829761 ! regulation of proteolysis GO:0030162 37 36 1,000 7,714E-04 0,02961991 ! phosphoinositide biosynthetic process GO:0046489 38 36 1,000 7,714E-04 0,0293048 ! positive regulation of cell cycle GO:0045787 39 39 1,000 9,055E-04 0,03403589 ! response to insulin stimulus GO:0032868 45 40 1,000 9,525E-04 0,03543001 ! exonuclease activity GO:0004527 42 41 1,000 1,001E-03 0,03683796 ! receptor-mediated endocytosis GO:0006898 43 41 1,000 1,001E-03 0,03646206 ! double-strand break repair GO:0006302 41 41 1,000 1,001E-03 0,03609376 ! ruffle GO:0001726 44 42 1,000 1,05E-03 0,03749403 ! induction of apoptosis by intracellular signals GO:0008629 46 43 1,000 1,1E-03 0,03890728 ! keratinocyte differentiation GO:0030216 46 43 1,000 1,1E-03 0,03852583 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 1,000 1,259E-03 0,04363994 ! aging GO:0007568 48 46 1,000 1,259E-03 0,04322033 ! protein amino acid lipidation GO:0006497 50 47 1,000 1,314E-03 0,04468101 ! immunoglobulin mediated immune response GO:0016064 50 47 1,000 1,314E-03 0,04425949 ! epidermal cell differentiation GO:0009913 51 48 1,000 1,37E-03 0,04572118 ! B cell mediated immunity GO:0019724 51 48 1,000 1,37E-03 0,04529784 ! ribonuclease activity GO:0004540 50 49 1,000 1,427E-03 0,04676044 ! lamellipodium GO:0030027 53 49 1,000 1,427E-03 0,04633534 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 1,000 1,486E-03 0,04779874 ! nuclear periphery GO:0034399 53 50 1,000 1,486E-03 0,04737196 ! regulation of DNA replication GO:0006275 56 50 1,000 1,486E-03 0,04695274 ! skeletal muscle fiber development GO:0048741 54 51 1,000 1,545E-03 0,04840768 ! lipoprotein biosynthetic process GO:0042158 54 51 1,000 1,545E-03 0,04798674 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 1,606E-03 0,04944246 ! regulation of actin filament length GO:0030832 53 52 1,000 1,606E-03 0,04901987 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 1,606E-03 0,04860445 ! muscle fiber development GO:0048747 55 52 1,000 1,606E-03 0,04819601 ! growth factor receptor binding GO:0070851 56 54 1,000 1,731E-03 0,05150912 ! regulation of protein catabolic process GO:0042176 57 54 1,000 1,731E-03 0,05108343 ! regulation of cellular component size GO:0032535 56 55 1,000 1,795E-03 0,05254096 ! response to peptide hormone stimulus GO:0043434 60 55 1,000 1,795E-03 0,0521138 ! glycerophospholipid biosynthetic process GO:0046474 59 55 1,000 1,795E-03 0,05169353 ! nucleotide-excision repair GO:0006289 58 55 1,000 1,795E-03 0,05127998 ! actin filament organization GO:0007015 59 56 1,000 1,86E-03 0,05272143 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 1,927E-03 0,05417162 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 1,994E-03 0,05563028 GO:0045937|positive regulation of phosphate metabolic process, ! ubiquitin thiolesterase activity GO:0004221 62 59 1,000 2,063E-03 0,05709714 ! lymphocyte mediated immunity GO:0002449 63 60 1,000 2,132E-03 0,05857194 ! phosphoinositide metabolic process GO:0030384 66 62 1,000 2,275E-03 0,06201423 ! glycerolipid biosynthetic process GO:0045017 66 62 1,000 2,275E-03 0,06154443 ! B cell activation GO:0042113 66 63 1,000 2,348E-03 0,06304163 ! adaptive immune response GO:0002250 68 65 1,000 2,497E-03 0,06654981 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! response to metal ion GO:0010038 69 65 1,000 2,497E-03 0,06605685 ! positive regulation of protein modification process GO:0031401 69 65 1,000 2,497E-03 0,06557114 ! lipoprotein metabolic process GO:0042157 68 65 1,000 2,497E-03 0,06509252 ! DNA-dependent DNA replication GO:0006261 66 65 1,000 2,497E-03 0,06462083 ! response to unfolded protein GO:0006986 68 66 1,000 2,574E-03 0,066116 ! muscle cell differentiation GO:0042692 68 68 1,000 2,729E-03 0,06961956 ! protein import into nucleus GO:0006606 72 68 1,000 2,729E-03 0,06912581 ! regulation of actin cytoskeleton organization GO:0032956 74 68 1,000 2,729E-03 0,068639 ! leukocyte mediated immunity GO:0002443 71 68 1,000 2,729E-03 0,06815901 ! extrinsic to membrane GO:0019898 68 68 1,000 2,729E-03 0,06768568 ! sarcomere GO:0030017 75 69 1,000 2,809E-03 0,06917854 ! nuclear import GO:0051170 74 70 1,000 2,89E-03 0,07067754 ! response to inorganic substance GO:0010035 74 70 1,000 2,89E-03 0,07019674 ! cell cortex GO:0005938 74 70 1,000 2,89E-03 0,06972244 ! regulation of actin filament-based process GO:0032970 77 71 1,000 2,971E-03 0,07121363 ! response to protein stimulus GO:0051789 74 72 1,000 3,054E-03 0,07271071 ! protein localization in nucleus GO:0034504 78 74 1,000 3,223E-03 0,07622336 ! myofibril GO:0030016 80 74 1,000 3,223E-03 0,07572189 ! cellular response to hormone stimulus GO:0032870 81 74 1,000 3,223E-03 0,07522698 ! nuclear chromosome part GO:0044454 76 74 1,000 3,223E-03 0,07473849 ! regulation of catabolic process GO:0009894 80 75 1,000 3,309E-03 0,07623907 ! structural constituent of cytoskeleton GO:0005200 81 75 1,000 3,309E-03 0,07575036 ! contractile fiber part GO:0044449 82 76 1,000 3,396E-03 0,0772498 ! endonuclease activity GO:0004519 80 77 1,000 3,485E-03 0,07875448 ! thiolester hydrolase activity GO:0016790 81 78 1,000 3,574E-03 0,08026424 ! blood coagulation GO:0007596 81 78 1,000 3,574E-03 0,07976259 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 1,000 3,664E-03 0,081271 ! contractile fiber GO:0043292 86 80 1,000 3,756E-03 0,08278426 ! protein kinase binding GO:0019901 89 80 1,000 3,756E-03 0,08227638 ! interphase of mitotic cell cycle GO:0051329 84 82 1,000 3,942E-03 0,08582475 GO:0051325|interphase, ! cell leading edge GO:0031252 90 83 1,000 4,036E-03 0,08735172 ! SH3 domain binding GO:0017124 97 83 1,000 4,036E-03 0,0868255 ! hemostasis GO:0007599 86 83 1,000 4,036E-03 0,08630559 ! phosphoinositide binding GO:0035091 90 83 1,000 4,036E-03 0,08579187 ! DNA recombination GO:0006310 86 85 1,000 4,228E-03 0,08934841 ! microtubule cytoskeleton organization GO:0000226 92 87 1,000 4,425E-03 0,09295143 ! skeletal muscle tissue development GO:0007519 92 88 1,000 4,525E-03 0,09449288 GO:0060538|skeletal muscle organ development, ! intermediate filament GO:0005882 92 90 1,000 4,728E-03 0,0981543 ! nuclear membrane GO:0031965 92 90 1,000 4,728E-03 0,09758693 ! intermediate filament cytoskeleton GO:0045111 93 91 1,000 4,831E-03 0,09913932 ! glycerophospholipid metabolic process GO:0006650 98 92 1,000 4,935E-03 0,10069513 ! chromatin binding GO:0003682 102 99 1,000 5,692E-03 0,11548043 ! nuclear chromosome GO:0000228 102 99 1,000 5,692E-03 0,114828 ! kinase binding GO:0019900 108 99 1,000 5,692E-03 0,1141829 ! Ras protein signal transduction GO:0007265 105 99 1,000 5,692E-03 0,11354501 ! tRNA transcription GO:0009304 5 5 0,000 5,756E-03 0,11420162 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 5,756E-03 0,11357067 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,756E-03 0,11294665 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 5,756E-03 0,11232946 ! response to oxygen radical GO:0000305 5 5 0,000 5,756E-03 0,11171897 ! positive regulation of axon extension GO:0045773 6 5 0,000 5,756E-03 0,11111509 ! negative regulation of bone resorption GO:0045779 5 5 0,000 5,756E-03 0,11051769 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 5,756E-03 0,10992669 ! regulation of interferon-beta production GO:0032648 6 5 0,000 5,756E-03 0,10934197 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 5,756E-03 0,10876345 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,756E-03 0,10819101 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 5,756E-03 0,10762456 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 5,756E-03 0,10706402 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,756E-03 0,10650928 ! N-terminal protein lipidation GO:0006498 5 5 0,000 5,756E-03 0,10596026 ! glycolipid transport GO:0046836 5 5 0,000 5,756E-03 0,10541688 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 5,756E-03 0,10487904 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 5,756E-03 0,10434666 ! protein amino acid sulfation GO:0006477 5 5 0,000 5,756E-03 0,10381965 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 5,756E-03 0,10329795 ! embryonic camera-type eye development GO:0031076 7 5 0,000 5,756E-03 0,10278146 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 5,756E-03 0,10227011 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,756E-03 0,10176382 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 5,756E-03 0,10126252 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 5,756E-03 0,10076613 ! elastic fiber assembly GO:0048251 5 5 0,000 5,756E-03 0,10027459 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 5,756E-03 0,09978782 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 5,756E-03 0,09930575 ! ruffle membrane GO:0032587 5 5 0,000 5,756E-03 0,09882832 ! regulation of histone modification GO:0031056 5 5 0,000 5,756E-03 0,09835546 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,756E-03 0,0978871 ! behavioral response to pain GO:0048266 5 5 0,000 5,756E-03 0,09742318 ! clathrin coat assembly GO:0048268 6 5 0,000 5,756E-03 0,09696364 ! Notch receptor processing GO:0007220 5 5 0,000 5,756E-03 0,09650841 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 5,756E-03 0,09605744 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 5,756E-03 0,09561066 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 5,756E-03 0,09516801 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 5,756E-03 0,09472945 ! response to lipid GO:0033993 5 5 0,000 5,756E-03 0,09429491 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 5,756E-03 0,09386434 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,756E-03 0,09343769 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 5,756E-03 0,09301489 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 5,756E-03 0,09259591 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 5,756E-03 0,09218068 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 5,756E-03 0,09176916 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,756E-03 0,09136129 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 5,756E-03 0,09095704 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,756E-03 0,09055635 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 5,756E-03 0,09015917 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 5,756E-03 0,08976546 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 5,756E-03 0,08937518 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,756E-03 0,08898827 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,756E-03 0,0886047 ! microfibril GO:0001527 5 5 0,000 5,756E-03 0,08822443 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 5,756E-03 0,0878474 ! toxin metabolic process GO:0009404 5 5 0,000 5,756E-03 0,08747358 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,756E-03 0,08710293 ! cytokine secretion GO:0050663 5 5 0,000 5,756E-03 0,08673541 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 5,756E-03 0,08637097 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,756E-03 0,08600959 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 5,756E-03 0,08565121 ! epithelial cell proliferation GO:0050673 5 5 0,000 5,756E-03 0,08529581 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 5,756E-03 0,08494335 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 5,756E-03 0,08459379 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 5,756E-03 0,0842471 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,756E-03 0,08390323 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 5,756E-03 0,08356216 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 5,756E-03 0,08322385 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,756E-03 0,08288827 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,756E-03 0,08255539 ! glutamate catabolic process GO:0006538 6 5 0,000 5,756E-03 0,08222516 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 5,756E-03 0,08189757 ! microvillus organization GO:0032528 5 5 0,000 5,756E-03 0,08157258 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 5,756E-03 0,08125016 ! L-serine biosynthetic process GO:0006564 5 5 0,000 5,756E-03 0,08093028 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,756E-03 0,08061291 ! pericentriolar material GO:0000242 6 5 0,000 5,756E-03 0,08029801 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,756E-03 0,07998557 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 5,756E-03 0,07967555 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 5,756E-03 0,07936792 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 5,756E-03 0,07906266 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 5,756E-03 0,07875974 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 5,756E-03 0,07845913 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 5,756E-03 0,0781608 ! response to tumor necrosis factor GO:0034612 6 5 0,000 5,756E-03 0,07786474 ! mRNA transcription GO:0009299 6 5 0,000 5,756E-03 0,07757091 ! response to ATP GO:0033198 5 5 0,000 5,756E-03 0,07727929 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 5,756E-03 0,07698985 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 5,756E-03 0,07670258 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,756E-03 0,07641744 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 5,756E-03 0,07613441 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,756E-03 0,07585347 ! multivesicular body GO:0005771 5 5 0,000 5,756E-03 0,0755746 ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,756E-03 0,07529777 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 5,756E-03 0,07502296 ! forebrain neuron development GO:0021884 6 5 0,000 5,756E-03 0,07475015 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 5,756E-03 0,07447932 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 5,756E-03 0,07421044 ! demethylase activity GO:0032451 5 5 0,000 5,756E-03 0,07394349 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 5,756E-03 0,07367846 ! epithelial cell maturation GO:0002070 5 5 0,000 5,756E-03 0,07341533 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 5,756E-03 0,07315406 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 5,756E-03 0,07289465 ! zymogen granule GO:0042588 5 5 0,000 5,756E-03 0,07263707 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 5,756E-03 0,07238131 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,756E-03 0,07212734 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,756E-03 0,07187514 ! early endosome to late endosome transport GO:0045022 5 5 0,000 5,756E-03 0,07162471 ! positive regulation of translational initiation GO:0045948 5 5 0,000 5,756E-03 0,07137601 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,756E-03 0,07112904 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,756E-03 0,07088376 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 5,756E-03 0,07064018 ! proteoglycan binding GO:0043394 9 5 0,000 5,756E-03 0,07039826 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 5,756E-03 0,07015799 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 5,756E-03 0,06991936 ! zinc ion homeostasis GO:0055069 5 5 0,000 5,756E-03 0,06968234 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 5,756E-03 0,06944693 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 5,756E-03 0,0692131 ! activated T cell proliferation GO:0050798 6 5 0,000 5,756E-03 0,06898084 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 5,756E-03 0,06875014 ! dynein binding GO:0045502 5 5 0,000 5,756E-03 0,06852097 ! regulation of dendrite development GO:0050773 5 5 0,000 5,756E-03 0,06829333 ! cardiac muscle cell development GO:0055013 5 5 0,000 5,756E-03 0,06806719 ! anterograde axon cargo transport GO:0008089 5 5 0,000 5,756E-03 0,06784255 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,756E-03 0,06761938 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,756E-03 0,06739768 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 5,756E-03 0,06717742 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,756E-03 0,0669586 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 5,756E-03 0,06674121 ! high-density lipoprotein binding GO:0008035 5 5 0,000 5,756E-03 0,06652521 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,756E-03 0,06631062 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 5,756E-03 0,0660974 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 5,756E-03 0,06588555 ! centromeric DNA binding GO:0019237 5 5 0,000 5,756E-03 0,06567505 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,756E-03 0,0654659 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,756E-03 0,06525807 ! positive T cell selection GO:0043368 9 5 0,000 5,756E-03 0,06505155 ! neural tube patterning GO:0021532 5 5 0,000 5,756E-03 0,06484634 ! amylase activity GO:0016160 5 5 0,000 5,756E-03 0,06464243 ! metaphase plate congression GO:0051310 5 5 0,000 5,756E-03 0,06443978 ! regulation of sterol transport GO:0032371 5 5 0,000 5,756E-03 0,06423841 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 5,756E-03 0,06403829 ! oxygen homeostasis GO:0032364 5 5 0,000 5,756E-03 0,06383941 ! skeletal muscle regeneration GO:0043403 5 5 0,000 5,756E-03 0,06364177 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 5,756E-03 0,06344534 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 5,756E-03 0,06325013 ! SAP kinase activity GO:0016909 5 5 0,000 5,756E-03 0,06305611 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 5,756E-03 0,06286328 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 5,756E-03 0,06267162 ! alpha-mannosidase activity GO:0004559 6 5 0,000 5,756E-03 0,06248113 ! alpha-glucosidase activity GO:0004558 6 5 0,000 5,756E-03 0,06229179 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,756E-03 0,0621036 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 5,756E-03 0,06191654 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 5,756E-03 0,0617306 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,756E-03 0,06154578 ! CARD domain binding GO:0050700 5 5 0,000 5,756E-03 0,06136206 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 5,756E-03 0,06117944 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,756E-03 0,0609979 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 5,756E-03 0,06081743 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,756E-03 0,06063803 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,756E-03 0,06045968 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,756E-03 0,06028238 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 5,756E-03 0,06010611 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 5,756E-03 0,05993088 ! ceramidase activity GO:0017040 5 5 0,000 5,756E-03 0,05975666 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 5,756E-03 0,05958345 ! GTP-Rho binding GO:0017049 5 5 0,000 5,756E-03 0,05941125 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,756E-03 0,05924003 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 5,756E-03 0,0590698 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 5,756E-03 0,05890055 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 5,756E-03 0,05873226 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,756E-03 0,05856493 ! TAP complex GO:0042825 5 5 0,000 5,756E-03 0,05839855 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,756E-03 0,05823312 ! actinin binding GO:0042805 6 5 0,000 5,756E-03 0,05806862 ! secretory granule organization GO:0033363 5 5 0,000 5,756E-03 0,05790505 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,756E-03 0,05774239 ! striatum development GO:0021756 5 5 0,000 5,756E-03 0,05758065 ! photoreceptor inner segment GO:0001917 5 5 0,000 5,756E-03 0,05741981 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 5,756E-03 0,05725986 ! aldehyde-lyase activity GO:0016832 5 5 0,000 5,756E-03 0,05710081 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 5,756E-03 0,05694263 ! T cell activation during immune response GO:0002286 5 5 0,000 5,756E-03 0,05678533 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,756E-03 0,0566289 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 5,756E-03 0,05647333 ! dystroglycan complex GO:0016011 6 5 0,000 5,756E-03 0,05631861 ! neural plate development GO:0001840 5 5 0,000 5,756E-03 0,05616473 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 5,756E-03 0,05601169 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,756E-03 0,05585949 ! phosphopantetheine binding GO:0031177 5 5 0,000 5,756E-03 0,05570811 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,756E-03 0,05555754 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 5,756E-03 0,05540779 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 5,756E-03 0,05525885 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,756E-03 0,0551107 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 5,756E-03 0,05496335 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 5,756E-03 0,05481678 ! retina homeostasis GO:0001895 5 5 0,000 5,756E-03 0,05467099 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 5,756E-03 0,05452597 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 5,756E-03 0,05438172 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 5,756E-03 0,05423824 ! collagen type IV GO:0005587 5 5 0,000 5,756E-03 0,0540955 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,756E-03 0,05395352 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 5,756E-03 0,05381228 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 5,756E-03 0,05367178 ! spindle assembly GO:0051225 5 5 0,000 5,756E-03 0,05353201 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,756E-03 0,05339296 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 5,756E-03 0,05325464 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 5,756E-03 0,05311703 ! protein amino acid prenylation GO:0018346 5 5 0,000 5,756E-03 0,05298013 ! stem cell division GO:0017145 5 5 0,000 5,756E-03 0,05284394 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,756E-03 0,05270844 ! phospholipid scrambling GO:0017121 5 5 0,000 5,756E-03 0,05257363 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 5,756E-03 0,05243952 ! regulation of humoral immune response GO:0002920 9 5 0,000 5,756E-03 0,05230608 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 5,756E-03 0,05217333 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 5,756E-03 0,05204124 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 5,756E-03 0,05190983 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,756E-03 0,05177907 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 5,756E-03 0,05164897 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 5,756E-03 0,05151953 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,756E-03 0,05139073 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,756E-03 0,05126257 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,756E-03 0,05113505 ! polyol transport GO:0015791 6 5 0,000 5,756E-03 0,05100817 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 5,756E-03 0,05088191 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,756E-03 0,05075627 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 5,756E-03 0,05063126 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 5,756E-03 0,05050686 ! cobalt ion transport GO:0006824 5 5 0,000 5,756E-03 0,05038307 ! response to zinc ion GO:0010043 5 5 0,000 5,756E-03 0,05025988 ! poly(U) RNA binding GO:0008266 5 5 0,000 5,756E-03 0,0501373 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 5,756E-03 0,05001531 ! adaptation of signaling pathway GO:0022401 5 5 0,000 5,756E-03 0,04989391 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 5,756E-03 0,0497731 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 5,756E-03 0,04965288 ! sensory perception of bitter taste GO:0050913 5 5 0,000 5,756E-03 0,04953323 ! regulation of dopamine uptake GO:0051584 5 5 0,000 5,756E-03 0,04941416 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 5,756E-03 0,04929566 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,756E-03 0,04917773 ! neuron remodeling GO:0016322 6 5 0,000 5,756E-03 0,04906036 ! neurexin binding GO:0042043 5 5 0,000 5,756E-03 0,04894355 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 5,756E-03 0,0488273 ! regulation of potassium ion transport GO:0043266 5 5 0,000 5,756E-03 0,04871159 ! low-density lipoprotein particle GO:0034362 5 5 0,000 5,756E-03 0,04859643 ! chemoattractant activity GO:0042056 5 5 0,000 5,756E-03 0,04848182 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 5,756E-03 0,04836774 ! lipoic acid binding GO:0031405 5 5 0,000 5,756E-03 0,0482542 ! lithium ion binding GO:0031403 6 5 0,000 5,756E-03 0,0481412 ! lipoprotein particle clearance GO:0034381 5 5 0,000 5,756E-03 0,04802872 ! grooming behavior GO:0007625 5 5 0,000 5,756E-03 0,04791676 ! sequestering of actin monomers GO:0042989 5 5 0,000 5,756E-03 0,04780533 ! cobalamin binding GO:0031419 5 5 0,000 5,756E-03 0,04769441 ! retinoic acid binding GO:0001972 5 5 0,000 5,756E-03 0,04758401 ! response to axon injury GO:0048678 5 5 0,000 5,756E-03 0,04747411 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,756E-03 0,04736473 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 5,756E-03 0,04725584 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 5,756E-03 0,04714746 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 5,756E-03 0,04703957 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 5,756E-03 0,04693217 ! female pronucleus GO:0001939 5 5 0,000 5,756E-03 0,04682526 ! F-actin capping protein complex GO:0008290 5 5 0,000 5,756E-03 0,04671884 ! DNA topoisomerase activity GO:0003916 5 5 0,000 5,756E-03 0,04661291 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 5,756E-03 0,04650745 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 5,756E-03 0,04640246 ! dorsal spinal cord development GO:0021516 5 5 0,000 5,756E-03 0,04629795 ! ceramide catabolic process GO:0046514 5 5 0,000 5,756E-03 0,04619391 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,756E-03 0,04609034 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,756E-03 0,04598723 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 5,756E-03 0,04588458 ! Rap GTPase activator activity GO:0046582 5 5 0,000 5,756E-03 0,04578239 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 5,756E-03 0,04568065 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 5,756E-03 0,04557936 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 5,756E-03 0,04547852 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 5,756E-03 0,04537813 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 5,756E-03 0,04527817 ! neutrophil activation GO:0042119 5 5 0,000 5,756E-03 0,04517866 ! regulation of response to food GO:0032095 5 5 0,000 5,756E-03 0,04507959 ! response to food GO:0032094 5 5 0,000 5,756E-03 0,04498094 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,756E-03 0,04488273 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 5,756E-03 0,04478495 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,756E-03 0,04468759 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,756E-03 0,04459065 ! organ growth GO:0035265 7 5 0,000 5,756E-03 0,04449414 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 5,756E-03 0,04439804 ! small-subunit processome GO:0032040 5 5 0,000 5,756E-03 0,04430235 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 5,756E-03 0,04420708 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,756E-03 0,04411221 ! nucleoside salvage GO:0043174 7 5 0,000 5,756E-03 0,04401775 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 5,756E-03 0,0439237 ! GPI anchor binding GO:0034235 6 5 0,000 5,756E-03 0,04383005 ! thrombin receptor activity GO:0015057 5 5 0,000 5,756E-03 0,04373679 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 5,756E-03 0,04364393 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 5,756E-03 0,04355146 ! dendritic shaft GO:0043198 5 5 0,000 5,756E-03 0,04345939 ! terminal button GO:0043195 8 5 0,000 5,756E-03 0,0433677 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,756E-03 0,0432764 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 5,756E-03 0,04318549 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 5,756E-03 0,04309495 ! G2/M transition checkpoint GO:0031576 5 5 0,000 5,756E-03 0,04300479 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,756E-03 0,04291501 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 5,756E-03 0,04282561 ! response to UV-C GO:0010225 5 5 0,000 5,756E-03 0,04273657 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 5,756E-03 0,04264791 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 5,756E-03 0,04255961 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 5,756E-03 0,04247168 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 5,756E-03 0,04238411 ! IgE binding GO:0019863 5 5 0,000 5,756E-03 0,0422969 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 5,756E-03 0,04221004 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 5,756E-03 0,04212355 ! response to cadmium ion GO:0046686 5 5 0,000 5,756E-03 0,04203741 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 5,756E-03 0,04195161 ! hair follicle maturation GO:0048820 5 5 0,000 5,756E-03 0,04186617 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 5,756E-03 0,04178108 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 5,756E-03 0,04169633 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,756E-03 0,04161193 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,756E-03 0,04152786 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,756E-03 0,04144414 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,756E-03 0,04136075 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 5,756E-03 0,04127769 ! peroxisome fission GO:0016559 5 5 0,000 5,756E-03 0,04119497 ! alpha-tubulin binding GO:0043014 5 5 0,000 5,756E-03 0,04111258 ! mitotic recombination GO:0006312 5 5 0,000 5,756E-03 0,04103052 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,756E-03 0,04094879 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,756E-03 0,04086738 ! positive regulation of chemokine production GO:0032722 5 5 0,000 5,756E-03 0,04078629 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,756E-03 0,04070553 ! muscle cell proliferation GO:0033002 5 5 0,000 5,756E-03 0,04062508 ! membrane to membrane docking GO:0022614 5 5 0,000 5,756E-03 0,04054495 ! translation activator activity GO:0008494 5 5 0,000 5,756E-03 0,04046514 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 5,756E-03 0,04038564 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 5,756E-03 0,04030645 ! histamine receptor activity GO:0004969 5 5 0,000 5,756E-03 0,04022758 ! dopamine receptor activity GO:0004952 5 5 0,000 5,756E-03 0,04014901 ! galactosidase activity GO:0015925 5 5 0,000 5,756E-03 0,04007074 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 5,756E-03 0,03999278 ! cellular response to nutrient GO:0031670 5 5 0,000 5,756E-03 0,03991513 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 5,756E-03 0,03983777 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 5,756E-03 0,03976072 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 5,756E-03 0,03968396 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,756E-03 0,0396075 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 5,756E-03 0,03953133 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 5,756E-03 0,03945545 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 5,756E-03 0,03937987 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 5,756E-03 0,03930457 ! progesterone metabolic process GO:0042448 5 5 0,000 5,756E-03 0,03922956 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 5,756E-03 0,03915484 ! disaccharide metabolic process GO:0005984 5 5 0,000 5,756E-03 0,0390804 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 5,756E-03 0,03900625 ! histone acetyltransferase binding GO:0035035 5 5 0,000 5,756E-03 0,03893237 ! endosome to lysosome transport GO:0008333 5 5 0,000 5,756E-03 0,03885877 ! glial cell migration GO:0008347 5 5 0,000 5,756E-03 0,03878546 ! S-acyltransferase activity GO:0016417 5 5 0,000 5,756E-03 0,03871241 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 5,756E-03 0,03863965 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 5,756E-03 0,03856715 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,756E-03 0,03849493 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 5,756E-03 0,03842297 ! asparaginase activity GO:0004067 5 5 0,000 5,756E-03 0,03835129 ! insemination GO:0007320 5 5 0,000 5,756E-03 0,03827987 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,756E-03 0,03820872 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 5,756E-03 0,03813783 ! aminoacylase activity GO:0004046 5 5 0,000 5,756E-03 0,03806721 ! receptor biosynthetic process GO:0032800 5 5 0,000 5,756E-03 0,03799684 ! penetration of zona pellucida GO:0007341 5 5 0,000 5,756E-03 0,03792674 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 5,756E-03 0,03785689 ! aldehyde reductase activity GO:0004032 5 5 0,000 5,756E-03 0,0377873 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 5,756E-03 0,03771797 ! unconventional myosin complex GO:0016461 5 5 0,000 5,756E-03 0,03764888 ! carnitine metabolic process GO:0009437 5 5 0,000 5,756E-03 0,03758006 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 6,904E-03 0,04498935 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 6,904E-03 0,0449074 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 6,904E-03 0,04482575 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 6,904E-03 0,0447444 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 6,904E-03 0,04466334 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 6,904E-03 0,04458257 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 6,904E-03 0,0445021 ! ephrin receptor binding GO:0046875 7 6 0,000 6,904E-03 0,04442191 ! biotin binding GO:0009374 7 6 0,000 6,904E-03 0,04434202 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,904E-03 0,04426241 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 6,904E-03 0,04418309 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,904E-03 0,04410405 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 6,904E-03 0,04402529 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 6,904E-03 0,04394681 ! neuron adhesion GO:0007158 6 6 0,000 6,904E-03 0,04386862 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,904E-03 0,0437907 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 6,904E-03 0,04371305 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,904E-03 0,04363569 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 6,904E-03 0,04355859 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 6,904E-03 0,04348177 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 6,904E-03 0,04340522 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 6,904E-03 0,04332893 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,904E-03 0,04325292 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 6,904E-03 0,04317717 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,904E-03 0,04310168 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 6,904E-03 0,04302646 ! cytoplasmic microtubule GO:0005881 7 6 0,000 6,904E-03 0,0429515 ! Arp2/3 protein complex GO:0005885 7 6 0,000 6,904E-03 0,0428768 ! neurofilament GO:0005883 6 6 0,000 6,904E-03 0,04280237 ! glial cell fate commitment GO:0021781 6 6 0,000 6,904E-03 0,04272818 ! dynactin complex GO:0005869 6 6 0,000 6,904E-03 0,04265426 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 6,904E-03 0,04258059 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 6,904E-03 0,04250718 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 6,904E-03 0,04243401 ! lipopolysaccharide binding GO:0001530 6 6 0,000 6,904E-03 0,0423611 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,904E-03 0,04228844 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,904E-03 0,04221603 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 6,904E-03 0,04214387 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 6,904E-03 0,04207195 ! protein lipoylation GO:0009249 6 6 0,000 6,904E-03 0,04200028 ! cysteine metabolic process GO:0006534 6 6 0,000 6,904E-03 0,04192885 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 6,904E-03 0,04185766 ! histidine catabolic process GO:0006548 6 6 0,000 6,904E-03 0,04178672 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 6,904E-03 0,04171601 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 6,904E-03 0,04164554 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 6,904E-03 0,04157532 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 6,904E-03 0,04150532 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 6,904E-03 0,04143557 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 6,904E-03 0,04136604 ! microtubule nucleation GO:0007020 6 6 0,000 6,904E-03 0,04129675 ! proline biosynthetic process GO:0006561 7 6 0,000 6,904E-03 0,0412277 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,904E-03 0,04115887 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 6,904E-03 0,04109027 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 6,904E-03 0,0410219 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,904E-03 0,04095376 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 6,904E-03 0,04088584 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 6,904E-03 0,04081815 ! paraxial mesoderm development GO:0048339 6 6 0,000 6,904E-03 0,04075068 ! melanosome organization GO:0032438 6 6 0,000 6,904E-03 0,04068344 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 6,904E-03 0,04061641 ! flotillin complex GO:0016600 6 6 0,000 6,904E-03 0,04054961 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 6,904E-03 0,04048303 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 6,904E-03 0,04041666 ! positive regulation of exocytosis GO:0045921 7 6 0,000 6,904E-03 0,04035051 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 6,904E-03 0,04028458 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 6,904E-03 0,04021886 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,904E-03 0,04015336 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 6,904E-03 0,04008807 ! nonhomologous end joining complex GO:0070419 6 6 0,000 6,904E-03 0,04002299 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 6,904E-03 0,03995812 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 6,904E-03 0,03989347 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,904E-03 0,03982902 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,904E-03 0,03976478 ! sodium ion homeostasis GO:0055078 6 6 0,000 6,904E-03 0,03970074 ! protein heterooligomerization GO:0051291 6 6 0,000 6,904E-03 0,03963692 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 6,904E-03 0,03957329 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 6,904E-03 0,03950988 ! translation termination factor activity GO:0008079 6 6 0,000 6,904E-03 0,03944666 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 6,904E-03 0,03938365 ! astrocyte development GO:0014002 6 6 0,000 6,904E-03 0,03932083 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,904E-03 0,03925822 ! purine base biosynthetic process GO:0009113 7 6 0,000 6,904E-03 0,03919581 ! fibrinolysis GO:0042730 7 6 0,000 6,904E-03 0,03913359 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 6,904E-03 0,03907157 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 6,904E-03 0,03900975 ! B cell lineage commitment GO:0002326 6 6 0,000 6,904E-03 0,03894812 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 6,904E-03 0,03888669 ! response to exogenous dsRNA GO:0043330 6 6 0,000 6,904E-03 0,03882545 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 6,904E-03 0,03876441 ! melanosome transport GO:0032402 6 6 0,000 6,904E-03 0,03870355 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 6,904E-03 0,03864289 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 6,904E-03 0,03858241 ! regulation of dopamine secretion GO:0014059 6 6 0,000 6,904E-03 0,03852213 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 6,904E-03 0,03846203 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 6,904E-03 0,03840212 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,904E-03 0,0383424 ! transcription initiation factor activity GO:0016986 6 6 0,000 6,904E-03 0,03828286 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 6,904E-03 0,03822351 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,904E-03 0,03816434 ! Schwann cell development GO:0014044 6 6 0,000 6,904E-03 0,03810535 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 6,904E-03 0,03804655 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 6,904E-03 0,03798792 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,904E-03 0,03792948 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 6,904E-03 0,03787122 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,904E-03 0,03781313 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 6,904E-03 0,03775523 ! nuclear envelope lumen GO:0005641 6 6 0,000 6,904E-03 0,0376975 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 6,904E-03 0,03763994 ! regulation of meiosis GO:0040020 6 6 0,000 6,904E-03 0,03758256 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 6,904E-03 0,03752536 ! lipoxygenase activity GO:0016165 6 6 0,000 6,904E-03 0,03746833 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,904E-03 0,03741148 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 6,904E-03 0,03735479 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,904E-03 0,03729828 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 6,904E-03 0,03724194 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 6,904E-03 0,03718577 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,904E-03 0,03712976 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,904E-03 0,03707393 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,904E-03 0,03701826 ! chromatin silencing complex GO:0005677 6 6 0,000 6,904E-03 0,03696276 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 6,904E-03 0,03690743 ! B cell homeostasis GO:0001782 7 6 0,000 6,904E-03 0,03685226 ! regulation of respiratory burst GO:0060263 6 6 0,000 6,904E-03 0,03679726 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 6,904E-03 0,03674242 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 6,904E-03 0,03668774 ! MutLalpha complex GO:0032389 6 6 0,000 6,904E-03 0,03663323 ! leading edge membrane GO:0031256 6 6 0,000 6,904E-03 0,03657888 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 6,904E-03 0,03652468 ! peptidyl-histidine modification GO:0018202 6 6 0,000 6,904E-03 0,03647065 ! COPII vesicle coat GO:0030127 6 6 0,000 6,904E-03 0,03641678 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 6,904E-03 0,03636307 ! diuresis GO:0030146 6 6 0,000 6,904E-03 0,03630952 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 6,904E-03 0,03625612 ! glutathione biosynthetic process GO:0006750 6 6 0,000 6,904E-03 0,03620288 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 6,904E-03 0,0361498 ! BBSome GO:0034464 6 6 0,000 6,904E-03 0,03609687 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 6,904E-03 0,0360441 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 6,904E-03 0,03599148 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,904E-03 0,03593901 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,904E-03 0,0358867 ! glycolipid catabolic process GO:0019377 6 6 0,000 6,904E-03 0,03583454 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 6,904E-03 0,03578253 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 6,904E-03 0,03573067 ! porphyrin catabolic process GO:0006787 8 6 0,000 6,904E-03 0,03567896 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 6,904E-03 0,0356274 ! positive regulation of glucose import GO:0046326 7 6 0,000 6,904E-03 0,03557599 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 6,904E-03 0,03552473 ! myeloid cell homeostasis GO:0002262 6 6 0,000 6,904E-03 0,03547361 ! lamin binding GO:0005521 6 6 0,000 6,904E-03 0,03542265 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 6,904E-03 0,03537183 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 6,904E-03 0,03532115 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 6,904E-03 0,03527062 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 6,904E-03 0,03522023 ! peroxiredoxin activity GO:0051920 6 6 0,000 6,904E-03 0,03516999 ! complement binding GO:0001848 8 6 0,000 6,904E-03 0,03511989 ! catecholamine transport GO:0051937 6 6 0,000 6,904E-03 0,03506993 ! regulation of sensory perception GO:0051931 6 6 0,000 6,904E-03 0,03502012 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 6,904E-03 0,03497044 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 6,904E-03 0,03492091 ! dipeptidase activity GO:0016805 6 6 0,000 6,904E-03 0,03487152 ! ether hydrolase activity GO:0016803 6 6 0,000 6,904E-03 0,03482226 ! FACIT collagen GO:0005593 6 6 0,000 6,904E-03 0,03477315 ! actin filament polymerization GO:0030041 8 6 0,000 6,904E-03 0,03472417 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,904E-03 0,03467533 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 6,904E-03 0,03462663 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 6,904E-03 0,03457807 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,904E-03 0,03452964 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 6,904E-03 0,03448135 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,904E-03 0,03443319 ! organ regeneration GO:0031100 6 6 0,000 6,904E-03 0,03438516 ! Golgi transport complex GO:0017119 6 6 0,000 6,904E-03 0,03433727 ! sheet-forming collagen GO:0030935 6 6 0,000 6,904E-03 0,03428952 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,904E-03 0,03424189 ! positive regulation of coagulation GO:0050820 7 6 0,000 6,904E-03 0,0341944 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 6,904E-03 0,03414704 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 6,904E-03 0,03409981 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 6,904E-03 0,03405271 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 6,904E-03 0,03400574 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 6,904E-03 0,0339589 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 6,904E-03 0,03391219 ! myoblast cell fate commitment GO:0048625 6 6 0,000 6,904E-03 0,03386561 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,904E-03 0,03381915 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 6,904E-03 0,03377283 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 6,904E-03 0,03372662 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 6,904E-03 0,03368055 ! nuclear telomere cap complex GO:0000783 6 6 0,000 6,904E-03 0,0336346 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 6,904E-03 0,03358878 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 6,904E-03 0,03354308 ! sterol carrier activity GO:0005498 6 6 0,000 6,904E-03 0,0334975 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 6,904E-03 0,03345205 ! succinate metabolic process GO:0006105 6 6 0,000 6,904E-03 0,03340672 ! myelin sheath GO:0043209 6 6 0,000 6,904E-03 0,03336152 ! perikaryon GO:0043204 7 6 0,000 6,904E-03 0,03331644 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 6,904E-03 0,03327147 ! malate metabolic process GO:0006108 6 6 0,000 6,904E-03 0,03322663 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 6,904E-03 0,03318191 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 6,904E-03 0,03313731 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 6,904E-03 0,03309284 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,904E-03 0,03304847 ! rhythmic behavior GO:0007622 7 6 0,000 6,904E-03 0,03300423 ! copulation GO:0007620 6 6 0,000 6,904E-03 0,03296011 ! erythrocyte maturation GO:0043249 6 6 0,000 6,904E-03 0,0329161 ! equilibrioception GO:0050957 6 6 0,000 6,904E-03 0,03287222 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,904E-03 0,03282845 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 6,904E-03 0,03278479 ! chemosensory behavior GO:0007635 6 6 0,000 6,904E-03 0,03274125 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 6,904E-03 0,03269783 ! mechanosensory behavior GO:0007638 6 6 0,000 6,904E-03 0,03265452 ! response to interferon-gamma GO:0034341 6 6 0,000 6,904E-03 0,03261133 ! spinal cord patterning GO:0021511 6 6 0,000 6,904E-03 0,03256825 ! cGMP-mediated signaling GO:0019934 6 6 0,000 6,904E-03 0,03252528 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 6,904E-03 0,03248243 ! activation of MAPKKK activity GO:0000185 6 6 0,000 6,904E-03 0,03243969 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 6,904E-03 0,03239706 ! glucosyltransferase activity GO:0046527 6 6 0,000 6,904E-03 0,03235454 ! sphingoid catabolic process GO:0046521 6 6 0,000 6,904E-03 0,03231214 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,904E-03 0,03226985 ! activin receptor activity GO:0017002 6 6 0,000 6,904E-03 0,03222766 ! ovulation GO:0030728 6 6 0,000 6,904E-03 0,03218559 ! dopamine binding GO:0035240 7 6 0,000 6,904E-03 0,03214363 ! hyperosmotic response GO:0006972 6 6 0,000 6,904E-03 0,03210177 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 6,904E-03 0,03206003 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 6,904E-03 0,03201839 ! nuclear localization sequence binding GO:0008139 6 6 0,000 6,904E-03 0,03197686 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,904E-03 0,03193544 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,904E-03 0,03189413 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 6,904E-03 0,03185292 ! poly(A) RNA binding GO:0008143 6 6 0,000 6,904E-03 0,03181182 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 6,904E-03 0,03177083 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 6,904E-03 0,03172994 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 6,904E-03 0,03168915 ! intracellular pH reduction GO:0051452 6 6 0,000 6,904E-03 0,03164848 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 6,904E-03 0,0316079 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 6,904E-03 0,03156743 ! neurotrophin binding GO:0043121 6 6 0,000 6,904E-03 0,03152706 ! ciliary rootlet GO:0035253 6 6 0,000 6,904E-03 0,0314868 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 6,904E-03 0,03144664 ! ruffle organization GO:0031529 6 6 0,000 6,904E-03 0,03140658 ! T cell mediated immunity GO:0002456 6 6 0,000 6,904E-03 0,03136662 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 6,904E-03 0,03132676 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 6,904E-03 0,03128701 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,904E-03 0,03124735 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 6,904E-03 0,0312078 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,904E-03 0,03116835 ! phospholipase D activity GO:0004630 6 6 0,000 6,904E-03 0,03112899 ! rRNA modification GO:0000154 6 6 0,000 6,904E-03 0,03108974 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,904E-03 0,03105058 ! neuronal ion channel clustering GO:0045161 6 6 0,000 6,904E-03 0,03101152 ! response to UV-B GO:0010224 6 6 0,000 6,904E-03 0,03097257 ! interaction with symbiont GO:0051702 6 6 0,000 6,904E-03 0,0309337 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 6,904E-03 0,03089494 ! IgG binding GO:0019864 6 6 0,000 6,904E-03 0,03085627 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 6,904E-03 0,0308177 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 6,904E-03 0,03077923 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 6,904E-03 0,03074085 ! response to copper ion GO:0046688 6 6 0,000 6,904E-03 0,03070257 ! DNA topological change GO:0006265 6 6 0,000 6,904E-03 0,03066438 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,904E-03 0,03062629 ! dendrite morphogenesis GO:0048813 6 6 0,000 6,904E-03 0,03058829 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 6,904E-03 0,03055039 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 6,904E-03 0,03051258 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 6,904E-03 0,03047486 ! nucleosome disassembly GO:0006337 6 6 0,000 6,904E-03 0,03043724 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 6,904E-03 0,03039971 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,904E-03 0,03036227 ! guanylyltransferase activity GO:0070568 6 6 0,000 6,904E-03 0,03032492 ! receptor internalization GO:0031623 7 6 0,000 6,904E-03 0,03028767 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 6,904E-03 0,03025051 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 6,904E-03 0,03021343 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 6,904E-03 0,03017645 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 6,904E-03 0,03013956 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 6,904E-03 0,03010276 ! NuRD complex GO:0016581 6 6 0,000 6,904E-03 0,03006605 ! nucleosome positioning GO:0016584 6 6 0,000 6,904E-03 0,03002943 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,904E-03 0,0299929 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 6,904E-03 0,02995645 ! glycine binding GO:0016594 8 6 0,000 6,904E-03 0,0299201 ! costamere GO:0043034 7 6 0,000 6,904E-03 0,02988383 ! A band GO:0031672 6 6 0,000 6,904E-03 0,02984765 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,904E-03 0,02981156 ! dopamine biosynthetic process GO:0042416 7 6 0,000 6,904E-03 0,02977556 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 6,904E-03 0,02973964 ! negative regulation of axon extension GO:0030517 6 6 0,000 6,904E-03 0,02970381 ! actin monomer binding GO:0003785 6 6 0,000 6,904E-03 0,02966807 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,904E-03 0,02963241 ! lysozyme activity GO:0003796 6 6 0,000 6,904E-03 0,02959683 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 6,904E-03 0,02956135 ! ATP catabolic process GO:0006200 6 6 0,000 6,904E-03 0,02952594 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,904E-03 0,02949062 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 6,904E-03 0,02945539 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 6,904E-03 0,02942024 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 6,904E-03 0,02938518 ! O-acetyltransferase activity GO:0016413 6 6 0,000 6,904E-03 0,02935019 ! CoA-ligase activity GO:0016405 6 6 0,000 6,904E-03 0,02931529 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,904E-03 0,02928048 ! IkappaB kinase complex GO:0008385 6 6 0,000 6,904E-03 0,02924574 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 6,904E-03 0,02921109 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,904E-03 0,02917652 ! aminomethyltransferase activity GO:0004047 6 6 0,000 6,904E-03 0,02914204 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 6,904E-03 0,02910763 ! alkaline phosphatase activity GO:0004035 6 6 0,000 6,904E-03 0,0290733 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 6,904E-03 0,02903906 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 8,05E-03 0,03382068 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 8,05E-03 0,03378094 ! sleep GO:0030431 7 7 0,000 8,05E-03 0,03374129 ! synaptonemal complex assembly GO:0007130 7 7 0,000 8,05E-03 0,03370174 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 8,05E-03 0,03366227 ! cell proliferation in forebrain GO:0021846 7 7 0,000 8,05E-03 0,0336229 ! proteasome regulatory particle GO:0005838 8 7 0,000 8,05E-03 0,03358362 ! meiotic prophase I GO:0007128 7 7 0,000 8,05E-03 0,03354444 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 8,05E-03 0,03350534 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 8,05E-03 0,03346633 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 8,05E-03 0,03342742 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 8,05E-03 0,0333886 ! diphosphotransferase activity GO:0016778 8 7 0,000 8,05E-03 0,03334986 ! actin-myosin filament sliding GO:0033275 7 7 0,000 8,05E-03 0,03331122 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 8,05E-03 0,03327266 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 8,05E-03 0,0332342 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 8,05E-03 0,03319582 ! macrophage chemotaxis GO:0048246 7 7 0,000 8,05E-03 0,03315753 ! cerebral cortex cell migration GO:0021795 7 7 0,000 8,05E-03 0,03311933 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 8,05E-03 0,03308122 ! membrane hyperpolarization GO:0060081 7 7 0,000 8,05E-03 0,0330432 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 8,05E-03 0,03300526 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 8,05E-03 0,03296741 ! DNA replication origin binding GO:0003688 7 7 0,000 8,05E-03 0,03292965 ! ATPase binding GO:0051117 7 7 0,000 8,05E-03 0,03289197 ! positive regulation of glycolysis GO:0045821 7 7 0,000 8,05E-03 0,03285438 ! positive regulation of isotype switching GO:0045830 11 7 0,000 8,05E-03 0,03281687 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 8,05E-03 0,03277945 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 8,05E-03 0,03274212 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 8,05E-03 0,03270487 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 8,05E-03 0,03266771 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 8,05E-03 0,03263063 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 8,05E-03 0,03259363 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 8,05E-03 0,03255672 ! transepithelial chloride transport GO:0030321 7 7 0,000 8,05E-03 0,03251989 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 8,05E-03 0,03248314 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 8,05E-03 0,03244648 ! glycine catabolic process GO:0006546 7 7 0,000 8,05E-03 0,0324099 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 8,05E-03 0,0323734 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 8,05E-03 0,03233699 ! response to pH GO:0009268 7 7 0,000 8,05E-03 0,03230065 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 8,05E-03 0,0322644 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 8,05E-03 0,03222823 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 8,05E-03 0,03219214 ! endosome organization GO:0007032 7 7 0,000 8,05E-03 0,03215613 ! thyroid hormone generation GO:0006590 7 7 0,000 8,05E-03 0,0321202 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 8,05E-03 0,03208435 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 8,05E-03 0,03204859 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 8,05E-03 0,0320129 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 8,05E-03 0,03197729 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 8,05E-03 0,03194176 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 8,05E-03 0,03190631 ! retinoid X receptor binding GO:0046965 7 7 0,000 8,05E-03 0,03187093 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 8,05E-03 0,03183564 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 8,05E-03 0,03180042 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 8,05E-03 0,03176528 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 8,05E-03 0,03173022 ! urea metabolic process GO:0019627 7 7 0,000 8,05E-03 0,03169524 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 8,05E-03 0,03166033 ! regulation of type I interferon production GO:0032479 8 7 0,000 8,05E-03 0,0316255 ! peroxisomal matrix GO:0005782 7 7 0,000 8,05E-03 0,03159075 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 8,05E-03 0,03155607 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 8,05E-03 0,03152147 ! p53 binding GO:0002039 7 7 0,000 8,05E-03 0,03148695 ! osteoblast development GO:0002076 8 7 0,000 8,05E-03 0,0314525 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 8,05E-03 0,03141812 ! lipid phosphatase activity GO:0042577 7 7 0,000 8,05E-03 0,03138382 ! male sex determination GO:0030238 7 7 0,000 8,05E-03 0,0313496 ! clathrin binding GO:0030276 8 7 0,000 8,05E-03 0,03131545 ! negative regulation of translational initiation GO:0045947 7 7 0,000 8,05E-03 0,03128137 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 8,05E-03 0,03124737 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 8,05E-03 0,03121344 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 8,05E-03 0,03117959 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 8,05E-03 0,03114581 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 8,05E-03 0,0311121 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 8,05E-03 0,03107847 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 8,05E-03 0,0310449 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 8,05E-03 0,03101141 ! hyaluronan metabolic process GO:0030212 8 7 0,000 8,05E-03 0,030978 ! protein retention in ER lumen GO:0006621 7 7 0,000 8,05E-03 0,03094465 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 8,05E-03 0,03091138 ! peptidyl-arginine modification GO:0018195 7 7 0,000 8,05E-03 0,03087818 ! regulation of circadian rhythm GO:0042752 7 7 0,000 8,05E-03 0,03084504 ! Hsp90 protein binding GO:0051879 7 7 0,000 8,05E-03 0,03081198 ! MutSalpha complex binding GO:0032407 8 7 0,000 8,05E-03 0,030779 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 8,05E-03 0,03074608 ! establishment of melanosome localization GO:0032401 7 7 0,000 8,05E-03 0,03071323 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 8,05E-03 0,03068045 ! gas homeostasis GO:0033483 7 7 0,000 8,05E-03 0,03064774 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 8,05E-03 0,0306151 ! subpallium development GO:0021544 7 7 0,000 8,05E-03 0,03058253 ! laminin-1 complex GO:0005606 7 7 0,000 8,05E-03 0,03055003 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 8,05E-03 0,0305176 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 8,05E-03 0,03048524 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 8,05E-03 0,03045295 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 8,05E-03 0,03042072 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 8,05E-03 0,03038856 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 8,05E-03 0,03035647 ! establishment of chromosome localization GO:0051303 7 7 0,000 8,05E-03 0,03032445 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 8,05E-03 0,0302925 ! regulation of cell division GO:0051302 7 7 0,000 8,05E-03 0,03026061 ! chromatin assembly complex GO:0005678 7 7 0,000 8,05E-03 0,03022879 ! sex chromatin GO:0001739 7 7 0,000 8,05E-03 0,03019704 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 8,05E-03 0,03016535 ! chitinase activity GO:0004568 7 7 0,000 8,05E-03 0,03013373 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 8,05E-03 0,03010218 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 8,05E-03 0,03007069 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 8,05E-03 0,03003927 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 8,05E-03 0,03000791 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 8,05E-03 0,02997662 ! molybdenum ion binding GO:0030151 7 7 0,000 8,05E-03 0,0299454 ! centriolar satellite GO:0034451 8 7 0,000 8,05E-03 0,02991424 ! positive regulation of epidermis development GO:0045684 7 7 0,000 8,05E-03 0,02988314 ! proteasome regulator activity GO:0010860 7 7 0,000 8,05E-03 0,02985211 ! antibiotic transport GO:0042891 7 7 0,000 8,05E-03 0,02982114 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 8,05E-03 0,02979024 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 8,05E-03 0,0297594 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 8,05E-03 0,02972863 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 8,05E-03 0,02969791 ! Wnt receptor activity GO:0042813 7 7 0,000 8,05E-03 0,02966727 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 8,05E-03 0,02963668 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 8,05E-03 0,02960616 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 8,05E-03 0,0295757 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 8,05E-03 0,0295453 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 8,05E-03 0,02951497 ! blastocyst growth GO:0001832 7 7 0,000 8,05E-03 0,0294847 ! pigment granule transport GO:0051904 7 7 0,000 8,05E-03 0,02945449 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 8,05E-03 0,02942434 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 8,05E-03 0,02939426 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 8,05E-03 0,02936423 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 8,05E-03 0,02933427 ! cerebellar cortex formation GO:0021697 8 7 0,000 8,05E-03 0,02930436 ! activation of innate immune response GO:0002218 7 7 0,000 8,05E-03 0,02927452 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 8,05E-03 0,02924474 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 8,05E-03 0,02921502 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 8,05E-03 0,02918536 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 8,05E-03 0,02915576 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 8,05E-03 0,02912622 ! regulation of muscle adaptation GO:0043502 7 7 0,000 8,05E-03 0,02909674 ! sequestering of metal ion GO:0051238 7 7 0,000 8,05E-03 0,02906732 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 8,05E-03 0,02903796 ! membrane attack complex GO:0005579 7 7 0,000 8,05E-03 0,02900866 ! fibrinogen complex GO:0005577 7 7 0,000 8,05E-03 0,02897942 ! septin complex GO:0031105 9 7 0,000 8,05E-03 0,02895023 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 8,05E-03 0,02892111 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 8,05E-03 0,02889204 ! cellular anion homeostasis GO:0030002 7 7 0,000 8,05E-03 0,02886303 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 8,05E-03 0,02883408 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 8,05E-03 0,02880519 ! autophagic vacuole formation GO:0000045 8 7 0,000 8,05E-03 0,02877636 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 8,05E-03 0,02874758 ! translation initiation factor binding GO:0031369 7 7 0,000 8,05E-03 0,02871886 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 8,05E-03 0,0286902 ! activin binding GO:0048185 7 7 0,000 8,05E-03 0,0286616 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 8,05E-03 0,02863305 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 8,05E-03 0,02860456 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 8,05E-03 0,02857612 ! phototransduction, visible light GO:0007603 7 7 0,000 8,05E-03 0,02854775 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 8,05E-03 0,02851943 ! lipoprotein transport GO:0042953 7 7 0,000 8,05E-03 0,02849116 ! cell division site part GO:0032155 7 7 0,000 8,05E-03 0,02846295 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 8,05E-03 0,0284348 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 8,05E-03 0,0284067 ! phospholipid efflux GO:0033700 7 7 0,000 8,05E-03 0,02837866 ! glucocorticoid metabolic process GO:0008211 7 7 0,000 8,05E-03 0,02835067 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 8,05E-03 0,02832274 ! poly-purine tract binding GO:0070717 7 7 0,000 8,05E-03 0,02829486 ! T-helper 1 type immune response GO:0042088 7 7 0,000 8,05E-03 0,02826704 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 8,05E-03 0,02823927 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 8,05E-03 0,02821156 ! leukocyte degranulation GO:0043299 7 7 0,000 8,05E-03 0,0281839 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 8,05E-03 0,0281563 ! bile acid and bile salt transport GO:0015721 7 7 0,000 8,05E-03 0,02812875 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 8,05E-03 0,02810125 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 8,05E-03 0,02807381 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 8,05E-03 0,02804642 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 8,05E-03 0,02801909 ! pigment granule organization GO:0048753 7 7 0,000 8,05E-03 0,0279918 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 8,05E-03 0,02796457 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 8,05E-03 0,0279374 ! regulation of pigmentation during development GO:0048070 10 7 0,000 8,05E-03 0,02791027 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 8,05E-03 0,0278832 ! macrophage activation GO:0042116 7 7 0,000 8,05E-03 0,02785618 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 8,05E-03 0,02782922 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 8,05E-03 0,0278023 ! galactose metabolic process GO:0006012 7 7 0,000 8,05E-03 0,02777544 ! vesicle fusion GO:0006906 7 7 0,000 8,05E-03 0,02774863 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 8,05E-03 0,02772187 ! glycerol ether catabolic process GO:0044269 7 7 0,000 8,05E-03 0,02769517 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 8,05E-03 0,02766851 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 8,05E-03 0,02764191 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 8,05E-03 0,02761535 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 8,05E-03 0,02758885 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 8,05E-03 0,0275624 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 8,05E-03 0,027536 ! inclusion body GO:0016234 7 7 0,000 8,05E-03 0,02750965 ! parturition GO:0007567 7 7 0,000 8,05E-03 0,02748335 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 8,05E-03 0,0274571 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 8,05E-03 0,0274309 ! intercalated disc GO:0014704 8 7 0,000 8,05E-03 0,02740475 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 8,05E-03 0,02737865 ! neural nucleus development GO:0048857 7 7 0,000 8,05E-03 0,0273526 ! intermediate filament organization GO:0045109 8 7 0,000 8,05E-03 0,0273266 ! skeletal muscle contraction GO:0003009 7 7 0,000 8,05E-03 0,02730065 ! response to antibiotic GO:0046677 7 7 0,000 8,05E-03 0,02727475 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 8,05E-03 0,02724889 ! preribosome GO:0030684 7 7 0,000 8,05E-03 0,02722309 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 8,05E-03 0,02719733 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 8,05E-03 0,02717163 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 8,05E-03 0,02714597 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 8,05E-03 0,02712036 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 8,05E-03 0,0270948 ! phosphofructokinase activity GO:0008443 7 7 0,000 8,05E-03 0,02706929 ! postreplication repair GO:0006301 7 7 0,000 8,05E-03 0,02704382 ! gap junction channel activity GO:0005243 7 7 0,000 8,05E-03 0,0270184 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 8,05E-03 0,02699303 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 8,05E-03 0,02696771 ! transcription termination GO:0006353 8 7 0,000 8,05E-03 0,02694244 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 8,05E-03 0,02691721 ! tetracycline transporter activity GO:0008493 7 7 0,000 8,05E-03 0,02689203 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 8,05E-03 0,0268669 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 8,05E-03 0,02684181 ! melanocortin receptor activity GO:0004977 7 7 0,000 8,05E-03 0,02681677 ! coenzyme A metabolic process GO:0015936 8 7 0,000 8,05E-03 0,02679178 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 8,05E-03 0,02676684 ! regulation of macrophage activation GO:0043030 7 7 0,000 8,05E-03 0,02674194 ! cytidine deaminase activity GO:0004126 7 7 0,000 8,05E-03 0,02671708 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 8,05E-03 0,02669228 ! apical protein localization GO:0045176 7 7 0,000 8,05E-03 0,02666752 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 8,05E-03 0,0266428 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 8,05E-03 0,02661813 ! virion binding GO:0046790 10 7 0,000 8,05E-03 0,02659351 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 8,05E-03 0,02656893 ! protein prenyltransferase activity GO:0008318 7 7 0,000 8,05E-03 0,0265444 ! protein modification by small protein removal GO:0070646 7 7 0,000 8,05E-03 0,02651991 ! adult feeding behavior GO:0008343 7 7 0,000 8,05E-03 0,02649547 ! CoA carboxylase activity GO:0016421 7 7 0,000 8,05E-03 0,02647107 ! microtubule basal body GO:0005932 7 7 0,000 8,05E-03 0,02644672 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 8,05E-03 0,02642241 ! embryonic heart tube development GO:0035050 7 7 0,000 8,05E-03 0,02639815 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 8,05E-03 0,02637393 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 8,05E-03 0,02634975 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 8,05E-03 0,02632562 ! rRNA transcription GO:0009303 8 8 0,000 9,195E-03 0,03004259 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 9,195E-03 0,03001513 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 9,195E-03 0,02998772 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 9,195E-03 0,02996036 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 9,195E-03 0,02993305 ! cation:chloride symporter activity GO:0015377 9 8 0,000 9,195E-03 0,02990579 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 9,195E-03 0,02987857 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 9,195E-03 0,02985141 ! male meiosis GO:0007140 8 8 0,000 9,195E-03 0,0298243 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 9,195E-03 0,02979724 ! N-glycan processing GO:0006491 8 8 0,000 9,195E-03 0,02977022 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 9,195E-03 0,02974326 ! protein self-association GO:0043621 8 8 0,000 9,195E-03 0,02971634 ! RNA methylation GO:0001510 8 8 0,000 9,195E-03 0,02968947 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 9,195E-03 0,02966265 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 9,195E-03 0,02963588 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 9,195E-03 0,02960916 ! hexokinase activity GO:0004396 8 8 0,000 9,195E-03 0,02958248 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 9,195E-03 0,02955585 ! guanylate cyclase activity GO:0004383 8 8 0,000 9,195E-03 0,02952927 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 9,195E-03 0,02950274 ! troponin complex GO:0005861 9 8 0,000 9,195E-03 0,02947626 ! smoothened signaling pathway GO:0007224 8 8 0,000 9,195E-03 0,02944982 ! keratinocyte proliferation GO:0043616 8 8 0,000 9,195E-03 0,02942344 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 9,195E-03 0,02939709 ! ganglioside metabolic process GO:0001573 8 8 0,000 9,195E-03 0,0293708 ! reflex GO:0060004 11 8 0,000 9,195E-03 0,02934455 ! small protein activating enzyme activity GO:0008641 10 8 0,000 9,195E-03 0,02931835 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 9,195E-03 0,0292922 ! hemoglobin metabolic process GO:0020027 8 8 0,000 9,195E-03 0,02926609 ! protein targeting to ER GO:0045047 9 8 0,000 9,195E-03 0,02924003 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 9,195E-03 0,02921402 ! arginine catabolic process GO:0006527 8 8 0,000 9,195E-03 0,02918805 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 9,195E-03 0,02916213 ! malate dehydrogenase activity GO:0016615 8 8 0,000 9,195E-03 0,02913625 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 9,195E-03 0,02911042 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 9,195E-03 0,02908464 GO:0010833|telomere maintenance via telomere lengthening, ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 9,195E-03 0,0290589 ! proline metabolic process GO:0006560 9 8 0,000 9,195E-03 0,0290332 ! melanosome membrane GO:0033162 10 8 0,000 9,195E-03 0,02900756 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 9,195E-03 0,02898195 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 9,195E-03 0,0289564 ! melanin metabolic process GO:0006582 9 8 0,000 9,195E-03 0,02893088 ! death receptor activity GO:0005035 8 8 0,000 9,195E-03 0,02890542 ! Golgi lumen GO:0005796 8 8 0,000 9,195E-03 0,02887999 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 9,195E-03 0,02885462 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 9,195E-03 0,02882928 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 9,195E-03 0,02880399 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 9,195E-03 0,02877875 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 9,195E-03 0,02875355 ! Rac protein signal transduction GO:0016601 8 8 0,000 9,195E-03 0,02872839 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 9,195E-03 0,02870328 ! lens development in camera-type eye GO:0002088 8 8 0,000 9,195E-03 0,02867821 ! positive regulation of vasodilation GO:0045909 8 8 0,000 9,195E-03 0,02865319 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 9,195E-03 0,02862821 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 9,195E-03 0,02860327 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 9,195E-03 0,02857838 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 9,195E-03 0,02855352 ! Schwann cell differentiation GO:0014037 8 8 0,000 9,195E-03 0,02852872 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 9,195E-03 0,02850395 ! axon guidance receptor activity GO:0008046 8 8 0,000 9,195E-03 0,02847923 ! protein targeting to vacuole GO:0006623 8 8 0,000 9,195E-03 0,02845455 ! response to tropane GO:0014073 10 8 0,000 9,195E-03 0,02842992 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 9,195E-03 0,02840532 ! melanosome localization GO:0032400 8 8 0,000 9,195E-03 0,02838077 ! response to amine stimulus GO:0014075 10 8 0,000 9,195E-03 0,02835626 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 9,195E-03 0,0283318 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 9,195E-03 0,02830737 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 9,195E-03 0,02828299 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 9,195E-03 0,02825865 ! holo TFIIH complex GO:0005675 8 8 0,000 9,195E-03 0,02823435 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 9,195E-03 0,0282101 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 9,195E-03 0,02818588 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 9,195E-03 0,02816171 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 9,195E-03 0,02813758 ! vitamin transporter activity GO:0051183 8 8 0,000 9,195E-03 0,02811349 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 9,195E-03 0,02808944 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 9,195E-03 0,02806543 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 9,195E-03 0,02804146 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 9,195E-03 0,02801754 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 9,195E-03 0,02799365 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 9,195E-03 0,02796981 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 9,195E-03 0,027946 ! regulation of synaptogenesis GO:0051963 8 8 0,000 9,195E-03 0,02792224 ! oocyte differentiation GO:0009994 8 8 0,000 9,195E-03 0,02789852 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 9,195E-03 0,02787483 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 9,195E-03 0,02785119 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 9,195E-03 0,02782759 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 9,195E-03 0,02780403 ! establishment of pigment granule localization GO:0051905 8 8 0,000 9,195E-03 0,0277805 ! regulation of telomere maintenance GO:0032204 8 8 0,000 9,195E-03 0,02775702 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 9,195E-03 0,02773358 ! amino sugar catabolic process GO:0046348 8 8 0,000 9,195E-03 0,02771017 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 9,195E-03 0,02768681 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 9,195E-03 0,02766348 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 9,195E-03 0,0276402 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 9,195E-03 0,02761695 ! cholesterol transporter activity GO:0017127 8 8 0,000 9,195E-03 0,02759374 ! GABA receptor binding GO:0050811 8 8 0,000 9,195E-03 0,02757057 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 9,195E-03 0,02754744 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 9,195E-03 0,02752435 ! regulation of developmental growth GO:0048638 8 8 0,000 9,195E-03 0,0275013 ! GMP binding GO:0019002 10 8 0,000 9,195E-03 0,02747829 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 9,195E-03 0,02745531 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 9,195E-03 0,02743238 ! prostate gland development GO:0030850 8 8 0,000 9,195E-03 0,02740948 ! 7S RNA binding GO:0008312 9 8 0,000 9,195E-03 0,02738662 ! phosphate transport GO:0006817 9 8 0,000 9,195E-03 0,02736379 ! neutral lipid catabolic process GO:0046461 8 8 0,000 9,195E-03 0,02734101 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 9,195E-03 0,02731826 ! reproductive behavior GO:0019098 8 8 0,000 9,195E-03 0,02729556 ! cell volume homeostasis GO:0006884 9 8 0,000 9,195E-03 0,02727289 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 9,195E-03 0,02725025 ! oligopeptide transport GO:0006857 8 8 0,000 9,195E-03 0,02722766 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 9,195E-03 0,0272051 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 9,195E-03 0,02718258 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 9,195E-03 0,02716009 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 9,195E-03 0,02713765 ! titin binding GO:0031432 8 8 0,000 9,195E-03 0,02711524 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 9,195E-03 0,02709287 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 9,195E-03 0,02707053 ! bone resorption GO:0045453 8 8 0,000 9,195E-03 0,02704823 ! glycerolipid catabolic process GO:0046503 8 8 0,000 9,195E-03 0,02702597 ! endoderm development GO:0007492 8 8 0,000 9,195E-03 0,02700374 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 9,195E-03 0,02698156 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 9,195E-03 0,0269594 ! astrocyte differentiation GO:0048708 8 8 0,000 9,195E-03 0,02693729 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 9,195E-03 0,02691521 ! syncytium formation GO:0006949 8 8 0,000 9,195E-03 0,02689316 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 9,195E-03 0,02687116 ! B cell proliferation GO:0042100 8 8 0,000 9,195E-03 0,02684919 ! mannose metabolic process GO:0006013 10 8 0,000 9,195E-03 0,02682725 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 9,195E-03 0,02680535 ! asymmetric protein localization GO:0008105 8 8 0,000 9,195E-03 0,02678349 ! tumor necrosis factor binding GO:0043120 8 8 0,000 9,195E-03 0,02676166 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 9,195E-03 0,02673986 ! neuron apoptosis GO:0051402 8 8 0,000 9,195E-03 0,02671811 ! macroautophagy GO:0016236 9 8 0,000 9,195E-03 0,02669639 ! Cajal body GO:0015030 8 8 0,000 9,195E-03 0,0266747 ! O-methyltransferase activity GO:0008171 9 8 0,000 9,195E-03 0,02665305 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 9,195E-03 0,02663143 ! PcG protein complex GO:0031519 8 8 0,000 9,195E-03 0,02660985 ! ferric iron binding GO:0008199 9 8 0,000 9,195E-03 0,0265883 ! spindle checkpoint GO:0031577 8 8 0,000 9,195E-03 0,02656679 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 9,195E-03 0,02654531 ! segment specification GO:0007379 8 8 0,000 9,195E-03 0,02652387 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 9,195E-03 0,02650246 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 9,195E-03 0,02648109 ! cellular extravasation GO:0045123 9 8 0,000 9,195E-03 0,02645975 ! pronucleus GO:0045120 8 8 0,000 9,195E-03 0,02643845 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 9,195E-03 0,02641718 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 9,195E-03 0,02639594 ! Rac GTPase activator activity GO:0030675 9 8 0,000 9,195E-03 0,02637474 ! regulation of DNA repair GO:0006282 8 8 0,000 9,195E-03 0,02635357 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 9,195E-03 0,02633244 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 9,195E-03 0,02631134 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 9,195E-03 0,02629028 ! DNA ligation GO:0006266 8 8 0,000 9,195E-03 0,02626924 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 9,195E-03 0,02624824 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 9,195E-03 0,02622728 ! erythrocyte development GO:0048821 8 8 0,000 9,195E-03 0,02620635 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 9,195E-03 0,02618545 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 9,195E-03 0,02616458 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 9,195E-03 0,02614375 ! gamma-tubulin binding GO:0043015 8 8 0,000 9,195E-03 0,02612295 ! ribosome binding GO:0043022 9 8 0,000 9,195E-03 0,02610219 ! NADPH oxidase complex GO:0043020 8 8 0,000 9,195E-03 0,02608146 ! mRNA polyadenylation GO:0006378 8 8 0,000 9,195E-03 0,02606076 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 9,195E-03 0,02604009 ! adenylyltransferase activity GO:0070566 8 8 0,000 9,195E-03 0,02601946 ! zymogen activation GO:0031638 8 8 0,000 9,195E-03 0,02599885 ! axonal fasciculation GO:0007413 8 8 0,000 9,195E-03 0,02597829 ! T cell homeostasis GO:0043029 9 8 0,000 9,195E-03 0,02595775 ! negative regulation of nuclear division GO:0051784 8 8 0,000 9,195E-03 0,02593725 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 9,195E-03 0,02591677 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 9,195E-03 0,02589634 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 9,195E-03 0,02587593 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 9,195E-03 0,02585555 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 9,195E-03 0,02583521 ! wide pore channel activity GO:0022829 8 8 0,000 9,195E-03 0,0258149 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 9,195E-03 0,02579462 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 9,195E-03 0,02577437 ! hormone catabolic process GO:0042447 8 8 0,000 9,195E-03 0,02575416 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 9,195E-03 0,02573398 ! biogenic amine catabolic process GO:0042402 11 8 0,000 9,195E-03 0,02571382 ! Notch binding GO:0005112 8 8 0,000 9,195E-03 0,0256937 ! death receptor binding GO:0005123 8 8 0,000 9,195E-03 0,02567362 ! ATPase regulator activity GO:0060590 8 8 0,000 9,195E-03 0,02565356 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 9,195E-03 0,02563353 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 9,195E-03 0,02561354 ! calcium-release channel activity GO:0015278 8 8 0,000 9,195E-03 0,02559357 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 9,195E-03 0,02557364 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 9,195E-03 0,02555374 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 0,000 9,195E-03 0,02553387 ! nucleus localization GO:0051647 10 8 0,000 9,195E-03 0,02551403 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 9,195E-03 0,02549422 ! negative regulation of immune effector process GO:0002698 12 8 0,000 9,195E-03 0,02547444 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 9,195E-03 0,02545469 ! adenosine deaminase activity GO:0004000 8 8 0,000 9,195E-03 0,02543498 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 0,01033914 0,02857669 ! respiratory burst GO:0045730 9 9 0,000 0,01033914 0,02855459 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 0,000 0,01033914 0,02853252 ! telencephalon cell migration GO:0022029 9 9 0,000 0,01033914 0,02851049 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 0,01033914 0,02848849 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01033914 0,02846652 ! cGMP metabolic process GO:0046068 9 9 0,000 0,01033914 0,02844459 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 0,01033914 0,0284227 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 0,01033914 0,02840083 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 0,01033914 0,028379 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 0,01033914 0,02835721 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01033914 0,02833544 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 0,01033914 0,02831371 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 0,01033914 0,02829202 ! artery development GO:0060840 9 9 0,000 0,01033914 0,02827035 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 0,01033914 0,02824872 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 0,01033914 0,02822713 ! middle ear morphogenesis GO:0042474 9 9 0,000 0,01033914 0,02820556 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 0,01033914 0,02818403 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 0,01033914 0,02816253 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 0,01033914 0,02814107 ! lung alveolus development GO:0048286 9 9 0,000 0,01033914 0,02811964 ! ciliary or flagellar motility GO:0001539 9 9 0,000 0,01033914 0,02809824 ! beta-amyloid binding GO:0001540 10 9 0,000 0,01033914 0,02807687 ! pathogenesis GO:0009405 9 9 0,000 0,01033914 0,02805553 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 0,01033914 0,02803423 ! regulated secretory pathway GO:0045055 9 9 0,000 0,01033914 0,02801296 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 0,01033914 0,02799172 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01033914 0,02797052 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 0,01033914 0,02794934 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 0,01033914 0,0279282 ! histidine metabolic process GO:0006547 9 9 0,000 0,01033914 0,02790709 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 0,01033914 0,02788601 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 0,01033914 0,02786497 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 0,01033914 0,02784395 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 0,01033914 0,02782297 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 0,01033914 0,02780202 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 0,01033914 0,0277811 ! entry into host cell GO:0030260 9 9 0,000 0,01033914 0,02776021 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 0,01033914 0,02773936 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 0,01033914 0,02771853 ! retinoic acid metabolic process GO:0042573 9 9 0,000 0,01033914 0,02769774 ! retinol metabolic process GO:0042572 9 9 0,000 0,01033914 0,02767697 ! behavioral fear response GO:0001662 9 9 0,000 0,01033914 0,02765624 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 0,01033914 0,02763554 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 0,01033914 0,02761487 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 0,01033914 0,02759423 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 0,01033914 0,02757362 ! regulation of gliogenesis GO:0014013 9 9 0,000 0,01033914 0,02755305 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 0,01033914 0,0275325 ! pigment granule localization GO:0051875 9 9 0,000 0,01033914 0,02751198 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 0,01033914 0,0274915 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 0,01033914 0,02747104 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 0,01033914 0,02745062 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 0,01033914 0,02743023 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 0,01033914 0,02740986 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 0,01033914 0,02738953 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 0,01033914 0,02736922 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 0,01033914 0,02734895 ! nitric oxide metabolic process GO:0046209 9 9 0,000 0,01033914 0,02732871 GO:0006809|nitric oxide biosynthetic process, ! icosanoid secretion GO:0032309 9 9 0,000 0,01033914 0,02730849 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 0,01033914 0,02728831 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 0,01033914 0,02726816 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 0,01033914 0,02724803 ! sterol catabolic process GO:0016127 9 9 0,000 0,01033914 0,02722794 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 0,01033914 0,02720787 ! peptidyl-lysine modification GO:0018205 9 9 0,000 0,01033914 0,02718784 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 0,01033914 0,02716783 ! clathrin coat of coated pit GO:0030132 12 9 0,000 0,01033914 0,02714786 ! SNARE complex GO:0031201 10 9 0,000 0,01033914 0,02712791 ! ubiquinone metabolic process GO:0006743 10 9 0,000 0,01033914 0,02710799 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 0,01033914 0,0270881 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 0,01033914 0,02706824 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 0,01033914 0,02704841 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 0,01033914 0,02702861 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 0,01033914 0,02700884 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01033914 0,0269891 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01033914 0,02696938 ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 0,01033914 0,0269497 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 0,01033914 0,02693004 ! cholesterol efflux GO:0033344 9 9 0,000 0,01033914 0,02691041 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 0,01033914 0,02689081 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 0,01033914 0,02687124 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 0,01033914 0,0268517 ! anterior/posterior axis specification GO:0009948 9 9 0,000 0,01033914 0,02683218 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01033914 0,0268127 ! detection of calcium ion GO:0005513 10 9 0,000 0,01033914 0,02679324 ! negative regulation of glucose import GO:0046325 9 9 0,000 0,01033914 0,02677381 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 0,01033914 0,02675441 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 0,01033914 0,02673503 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 0,01033914 0,02671569 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 0,01033914 0,02669637 ! desmosome GO:0030057 9 9 0,000 0,01033914 0,02667708 ! prepulse inhibition GO:0060134 9 9 0,000 0,01033914 0,02665782 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 0,01033914 0,02663859 ! negative regulation of B cell activation GO:0050869 9 9 0,000 0,01033914 0,02661938 ! anchoring collagen GO:0030934 9 9 0,000 0,01033914 0,0266002 ! axon extension GO:0048675 10 9 0,000 0,01033914 0,02658105 ! neuron fate specification GO:0048665 9 9 0,000 0,01033914 0,02656193 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 0,01033914 0,02654283 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 0,01033914 0,02652377 ! virus-host interaction GO:0019048 13 9 0,000 0,01033914 0,02650473 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 0,01033914 0,02648571 ! pentose-phosphate shunt GO:0006098 9 9 0,000 0,01033914 0,02646673 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01033914 0,02644777 ! DNA bending activity GO:0008301 9 9 0,000 0,01033914 0,02642884 ! social behavior GO:0035176 9 9 0,000 0,01033914 0,02640993 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 0,01033914 0,02639105 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 0,01033914 0,0263722 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01033914 0,02635338 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 0,01033914 0,02633458 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 0,01033914 0,02631581 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 0,01033914 0,02629707 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 0,01033914 0,02627835 ! blood vessel remodeling GO:0001974 10 9 0,000 0,01033914 0,02625966 ! C-X-C chemokine binding GO:0019958 9 9 0,000 0,01033914 0,026241 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 0,01033914 0,02622236 ! exosome (RNase complex) GO:0000178 9 9 0,000 0,01033914 0,02620375 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 0,01033914 0,02618517 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 0,01033914 0,02616661 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 0,01033914 0,02614808 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 0,01033914 0,02612957 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 0,01033914 0,02611109 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 0,01033914 0,02609264 ! phagocytosis, engulfment GO:0006911 10 9 0,000 0,01033914 0,02607421 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 0,01033914 0,02605581 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 0,01033914 0,02603744 ! glutathione peroxidase activity GO:0004602 9 9 0,000 0,01033914 0,02601909 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 0,01033914 0,02600076 ! lysophospholipase activity GO:0004622 9 9 0,000 0,01033914 0,02598247 ! brain morphogenesis GO:0048854 9 9 0,000 0,01033914 0,02596419 ! apolipoprotein binding GO:0034185 9 9 0,000 0,01033914 0,02594595 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01033914 0,02592773 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 0,01033914 0,02590953 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 0,01033914 0,02589136 ! kinesin binding GO:0019894 9 9 0,000 0,01033914 0,02587322 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 0,01033914 0,0258551 ! renal water homeostasis GO:0003091 9 9 0,000 0,01033914 0,02583701 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 0,01033914 0,02581894 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01033914 0,0258009 ! histone methylation GO:0016571 10 9 0,000 0,01033914 0,02578288 ! mRNA cleavage GO:0006379 9 9 0,000 0,01033914 0,02576489 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 0,01033914 0,02574692 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 0,01033914 0,02572898 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 0,01033914 0,02571106 ! opioid receptor activity GO:0004985 9 9 0,000 0,01033914 0,02569317 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 0,01033914 0,0256753 ! salivary gland development GO:0007431 10 9 0,000 0,01033914 0,02565746 ! glucosidase activity GO:0015926 10 9 0,000 0,01033914 0,02563964 ! adrenoceptor activity GO:0004935 11 9 0,000 0,01033914 0,02562185 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 0,01033914 0,02560408 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 0,01033914 0,02558634 ! purine base metabolic process GO:0006144 11 9 0,000 0,01033914 0,02556862 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 0,01033914 0,02555092 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 0,01033914 0,02553325 ! receptor inhibitor activity GO:0030547 9 9 0,000 0,01033914 0,02551561 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 0,01033914 0,02549799 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 0,01033914 0,02548039 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 0,01033914 0,02546282 ! palmitoyltransferase activity GO:0016409 9 9 0,000 0,01033914 0,02544527 ! arylsulfatase activity GO:0004065 9 9 0,000 0,01033914 0,02542774 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 0,01033914 0,02541024 ! behavioral response to nicotine GO:0035095 9 9 0,000 0,01033914 0,02539277 ! adenylate kinase activity GO:0004017 10 9 0,000 0,01033914 0,02537531 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 0,01033914 0,02535789 ! mitochondrion localization GO:0051646 9 9 0,000 0,01033914 0,02534048 ! localization within membrane GO:0051668 9 9 0,000 0,01033914 0,0253231 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 0,01148171 0,02810224 ! lipid particle GO:0005811 10 10 0,000 0,01148171 0,028083 ! myotube differentiation GO:0014902 10 10 0,000 0,01148171 0,02806377 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 0,01148171 0,02804458 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 0,01148171 0,02802541 ! synapsis GO:0007129 10 10 0,000 0,01148171 0,02800627 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 0,01148171 0,02798715 ! UTP metabolic process GO:0046051 10 10 0,000 0,01148171 0,02796806 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 0,01148171 0,02794899 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 0,01148171 0,02792996 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 0,01148171 0,02791094 ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01148171 0,02789196 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 0,01148171 0,02787299 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 0,01148171 0,02785406 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 0,01148171 0,02783515 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 0,01148171 0,02781626 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 0,01148171 0,02779741 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 0,01148171 0,02777857 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01148171 0,02775977 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 0,01148171 0,02774098 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 0,01148171 0,02772223 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 0,01148171 0,0277035 ! melanocyte differentiation GO:0030318 10 10 0,000 0,01148171 0,02768479 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 0,01148171 0,02766611 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 0,01148171 0,02764745 ! L-serine metabolic process GO:0006563 11 10 0,000 0,01148171 0,02762882 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 0,01148171 0,02761022 ! lipase inhibitor activity GO:0055102 10 10 0,000 0,01148171 0,02759164 ! autophagic vacuole GO:0005776 11 10 0,000 0,01148171 0,02757308 ! NAD metabolic process GO:0019674 10 10 0,000 0,01148171 0,02755455 ! stereocilium GO:0032420 10 10 0,000 0,01148171 0,02753605 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01148171 0,02751757 ! regulation of sodium ion transport GO:0002028 10 10 0,000 0,01148171 0,02749911 ! forebrain cell migration GO:0021885 10 10 0,000 0,01148171 0,02748068 ! organelle subcompartment GO:0031984 11 10 0,000 0,01148171 0,02746227 ! chondrocyte differentiation GO:0002062 10 10 0,000 0,01148171 0,02744389 ! negative regulation of ossification GO:0030279 10 10 0,000 0,01148171 0,02742553 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 0,01148171 0,0274072 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 0,01148171 0,02738889 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 0,01148171 0,02737061 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 0,01148171 0,02735235 ! protein homotetramerization GO:0051289 11 10 0,000 0,01148171 0,02733412 ! regulation of dephosphorylation GO:0035303 12 10 0,000 0,01148171 0,02731591 ! oligodendrocyte development GO:0014003 10 10 0,000 0,01148171 0,02729772 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 0,01148171 0,02727956 ! response to dsRNA GO:0043331 10 10 0,000 0,01148171 0,02726142 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01148171 0,0272433 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 0,01148171 0,02722522 ! fucose catabolic process GO:0019317 11 10 0,000 0,01148171 0,02720715 GO:0042355|L-fucose catabolic process, ! retinal binding GO:0016918 10 10 0,000 0,01148171 0,02718911 ! leukocyte activation during immune response GO:0002366 10 10 0,000 0,01148171 0,02717109 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 0,01148171 0,0271531 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 0,01148171 0,02713513 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 0,01148171 0,02711718 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 0,01148171 0,02709926 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01148171 0,02708136 ! midbrain development GO:0030901 10 10 0,000 0,01148171 0,02706348 ! musculoskeletal movement GO:0050881 10 10 0,000 0,01148171 0,02704563 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 0,01148171 0,0270278 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 0,01148171 0,02701 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01148171 0,02699221 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 0,01148171 0,02697446 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01148171 0,02695672 ! regulation of RNA splicing GO:0043484 10 10 0,000 0,01148171 0,02693901 ! embryonic gut development GO:0048566 10 10 0,000 0,01148171 0,02692132 ! positive regulation of amine transport GO:0051954 10 10 0,000 0,01148171 0,02690366 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 0,01148171 0,02688602 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01148171 0,0268684 ! lysogeny GO:0030069 10 10 0,000 0,01148171 0,0268508 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 0,01148171 0,02683323 ! establishment of cell polarity GO:0030010 10 10 0,000 0,01148171 0,02681568 ! regulation of synapse organization GO:0050807 10 10 0,000 0,01148171 0,02679815 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 0,01148171 0,02678065 ! acyl-CoA binding GO:0000062 10 10 0,000 0,01148171 0,02676317 ! negative regulation of muscle development GO:0048635 11 10 0,000 0,01148171 0,02674571 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01148171 0,02672828 ! GDP binding GO:0019003 10 10 0,000 0,01148171 0,02671086 ! photoreceptor activity GO:0009881 10 10 0,000 0,01148171 0,02669347 ! cortical cytoskeleton organization GO:0030865 10 10 0,000 0,01148171 0,02667611 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 0,01148171 0,02665876 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 0,01148171 0,02664144 ! nucleotidase activity GO:0008252 10 10 0,000 0,01148171 0,02662414 ! detection of mechanical stimulus GO:0050982 10 10 0,000 0,01148171 0,02660686 ! protein complex disassembly GO:0043241 11 10 0,000 0,01148171 0,02658961 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 0,01148171 0,02657237 ! lateral plasma membrane GO:0016328 10 10 0,000 0,01148171 0,02655516 ! estrogen metabolic process GO:0008210 10 10 0,000 0,01148171 0,02653798 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 0,01148171 0,02652081 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 0,01148171 0,02650367 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 0,01148171 0,02648655 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 0,01148171 0,02646945 ! interleukin-1 binding GO:0019966 10 10 0,000 0,01148171 0,02645237 ! endothelial cell differentiation GO:0045446 10 10 0,000 0,01148171 0,02643532 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 0,01148171 0,02641828 ! acid phosphatase activity GO:0003993 10 10 0,000 0,01148171 0,02640127 ! regulation of stress fiber formation GO:0051492 13 10 0,000 0,01148171 0,02638428 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 0,01148171 0,02636731 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 0,01148171 0,02635037 ! telomeric DNA binding GO:0042162 11 10 0,000 0,01148171 0,02633345 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01148171 0,02631654 ! lipid digestion GO:0044241 10 10 0,000 0,01148171 0,02629966 ! multicellular organism growth GO:0035264 10 10 0,000 0,01148171 0,0262828 ! receptor clustering GO:0043113 10 10 0,000 0,01148171 0,02626597 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 0,01148171 0,02624915 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 0,01148171 0,02623236 ! adult heart development GO:0007512 12 10 0,000 0,01148171 0,02621558 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 0,01148171 0,02619883 ! signalosome GO:0008180 10 10 0,000 0,01148171 0,0261821 ! prefoldin complex GO:0016272 10 10 0,000 0,01148171 0,0261654 ! neuromuscular junction GO:0031594 10 10 0,000 0,01148171 0,02614871 ! regulation of bone resorption GO:0045124 11 10 0,000 0,01148171 0,02613204 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 0,01148171 0,0261154 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 0,01148171 0,02609877 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 0,01148171 0,02608217 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 0,01148171 0,02606559 ! taste receptor activity GO:0008527 10 10 0,000 0,01148171 0,02604903 ! Ran GTPase binding GO:0008536 10 10 0,000 0,01148171 0,02603249 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01148171 0,02601597 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 0,01148171 0,02599948 ! ribosome assembly GO:0042255 10 10 0,000 0,01148171 0,025983 ! DNA methylation GO:0006306 12 10 0,000 0,01148171 0,02596654 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 0,01148171 0,02595011 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 0,01148171 0,0259337 ! proteasome accessory complex GO:0022624 11 10 0,000 0,01148171 0,0259173 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 0,01148171 0,02590093 ! prostaglandin receptor activity GO:0004955 11 10 0,000 0,01148171 0,02588458 ! regulation of isotype switching GO:0045191 14 10 0,000 0,01148171 0,02586825 ! peptide transporter activity GO:0015197 10 10 0,000 0,01148171 0,02585194 ! regulation of leukocyte migration GO:0002685 10 10 0,000 0,01148171 0,02583565 ! retinoid-X receptor activity GO:0004886 10 10 0,000 0,01148171 0,02581938 ! GTPase inhibitor activity GO:0005095 10 10 0,000 0,01148171 0,02580313 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01148171 0,0257869 ! gamma-tubulin complex GO:0000930 12 10 0,000 0,01148171 0,02577069 ! germ cell migration GO:0008354 10 10 0,000 0,01148171 0,02575451 ! regulation of organic acid transport GO:0032890 10 10 0,000 0,01148171 0,02573834 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 0,01148171 0,02572219 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 0,01148171 0,02570607 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 0,01148171 0,02568996 ! sterol transporter activity GO:0015248 10 10 0,000 0,01148171 0,02567387 ! regulation of embryonic development GO:0045995 11 10 0,000 0,01148171 0,02565781 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 0,01262303 0,02819064 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 0,01262303 0,02817302 ! negative regulation of blood pressure GO:0045776 11 11 0,000 0,01262303 0,02815542 ! RNA cap binding GO:0000339 12 11 0,000 0,01262303 0,02813785 ! CTP metabolic process GO:0046036 12 11 0,000 0,01262303 0,02812029 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 0,01262303 0,02810276 ! response to pain GO:0048265 11 11 0,000 0,01262303 0,02808525 ! axonemal dynein complex GO:0005858 11 11 0,000 0,01262303 0,02806777 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 0,01262303 0,0280503 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 0,01262303 0,02803286 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 0,01262303 0,02801543 ! endocrine pancreas development GO:0031018 11 11 0,000 0,01262303 0,02799803 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 0,01262303 0,02798065 ! regulation of exit from mitosis GO:0007096 11 11 0,000 0,01262303 0,02796329 ! chylomicron GO:0042627 11 11 0,000 0,01262303 0,02794596 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 0,01262303 0,02792864 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 0,01262303 0,02791135 ! transforming growth factor beta binding GO:0050431 11 11 0,000 0,01262303 0,02789408 ! glutamate metabolic process GO:0006536 12 11 0,000 0,01262303 0,02787683 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 0,01262303 0,0278596 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01262303 0,02784239 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 0,01262303 0,0278252 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 0,01262303 0,02780804 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 0,01262303 0,02779089 ! epithelial cell development GO:0002064 11 11 0,000 0,01262303 0,02777377 ! filamentous actin GO:0031941 11 11 0,000 0,01262303 0,02775667 ! temperature homeostasis GO:0001659 11 11 0,000 0,01262303 0,02773959 ! structural constituent of epidermis GO:0030280 13 11 0,000 0,01262303 0,02772253 ! protein targeting to peroxisome GO:0006625 11 11 0,000 0,01262303 0,02770549 ! spectrin GO:0008091 11 11 0,000 0,01262303 0,02768847 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 0,01262303 0,02767147 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 0,01262303 0,0276545 ! regulation of phagocytosis GO:0050764 11 11 0,000 0,01262303 0,02763754 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 0,01262303 0,02762061 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 0,01262303 0,02760369 ! regulation of B cell differentiation GO:0045577 15 11 0,000 0,01262303 0,0275868 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 0,01262303 0,02756993 ! basal lamina GO:0005605 12 11 0,000 0,01262303 0,02755308 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 0,01262303 0,02753624 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 0,01262303 0,02751943 ! hindbrain morphogenesis GO:0021575 13 11 0,000 0,01262303 0,02750264 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 0,01262303 0,02748587 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 0,01262303 0,02746912 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 0,01262303 0,02745239 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 0,01262303 0,02743569 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 0,01262303 0,027419 ! cofactor transporter activity GO:0051184 11 11 0,000 0,01262303 0,02740233 ! cobalt ion binding GO:0050897 11 11 0,000 0,01262303 0,02738568 ! pseudouridine synthase activity GO:0009982 12 11 0,000 0,01262303 0,02736905 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 0,01262303 0,02735245 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 0,01262303 0,02733586 ! histone deacetylase binding GO:0042826 11 11 0,000 0,01262303 0,02731929 ! thymus development GO:0048538 12 11 0,000 0,01262303 0,02730274 ! spleen development GO:0048536 12 11 0,000 0,01262303 0,02728622 ! regulation of RNA stability GO:0043487 11 11 0,000 0,01262303 0,02726971 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 0,01262303 0,02725322 ! acid-thiol ligase activity GO:0016878 11 11 0,000 0,01262303 0,02723676 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 0,01262303 0,02722031 ! blastocyst formation GO:0001825 11 11 0,000 0,01262303 0,02720388 ! cerebellar cortex development GO:0021695 12 11 0,000 0,01262303 0,02718747 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 0,01262303 0,02717109 ! folic acid binding GO:0005542 11 11 0,000 0,01262303 0,02715472 ! FK506 binding GO:0005528 11 11 0,000 0,01262303 0,02713837 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 0,01262303 0,02712204 ! extracellular matrix binding GO:0050840 13 11 0,000 0,01262303 0,02710573 ! microspike assembly GO:0030035 13 11 0,000 0,01262303 0,02708944 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 0,01262303 0,02707317 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 0,01262303 0,02705692 ! organ formation GO:0048645 12 11 0,000 0,01262303 0,02704069 ! positive regulation of B cell proliferation GO:0030890 15 11 0,000 0,01262303 0,02702448 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 0,01262303 0,02700829 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 0,01262303 0,02699211 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 0,01262303 0,02697596 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 0,01262303 0,02695983 ! Golgi vesicle budding GO:0048194 11 11 0,000 0,01262303 0,02694371 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 0,01262303 0,02692762 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01262303 0,02691154 ! ion channel inhibitor activity GO:0008200 13 11 0,000 0,01262303 0,02689548 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 0,01262303 0,02687945 ! MAP kinase kinase activity GO:0004708 11 11 0,000 0,01262303 0,02686343 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 0,01262303 0,02684743 ! mannosyltransferase activity GO:0000030 11 11 0,000 0,01262303 0,02683145 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 0,01262303 0,02681549 ! FMN binding GO:0010181 11 11 0,000 0,01262303 0,02679954 ! response to X-ray GO:0010165 12 11 0,000 0,01262303 0,02678362 ! focal adhesion formation GO:0048041 13 11 0,000 0,01262303 0,02676771 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 0,01262303 0,02675183 ! substrate-bound cell migration GO:0006929 11 11 0,000 0,01262303 0,02673596 ! integrator complex GO:0032039 11 11 0,000 0,01262303 0,02672011 ! L-glutamate transport GO:0015813 11 11 0,000 0,01262303 0,02670428 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 0,01262303 0,02668847 ! regulation of organ growth GO:0046620 12 11 0,000 0,01262303 0,02667268 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 0,01262303 0,02665691 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 0,01262303 0,02664115 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 0,01262303 0,02662542 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 0,01262303 0,0266097 ! histone acetylation GO:0016573 11 11 0,000 0,01262303 0,026594 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 0,01262303 0,02657832 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 0,01262303 0,02656266 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 0,01262303 0,02654701 ! chromatin silencing GO:0006342 11 11 0,000 0,01262303 0,02653139 ! gland morphogenesis GO:0022612 12 11 0,000 0,01262303 0,02651578 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 0,01262303 0,02650019 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 0,01262303 0,02648462 ! icosanoid receptor activity GO:0004953 12 11 0,000 0,01262303 0,02646907 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 0,01262303 0,02645354 ! negative regulation of neurological system process GO:0031645 12 11 0,000 0,01262303 0,02643802 ! acid secretion GO:0046717 11 11 0,000 0,01262303 0,02642253 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 0,01262303 0,02640705 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 0,01262303 0,02639159 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 0,01262303 0,02637614 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 0,01262303 0,02636072 ! midbody GO:0030496 11 11 0,000 0,01262303 0,02634531 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 0,01262303 0,02632992 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 0,01262303 0,02631455 ! water channel activity GO:0015250 11 11 0,000 0,01262303 0,0262992 ! response to nicotine GO:0035094 11 11 0,000 0,01262303 0,02628387 ! response to cold GO:0009409 11 11 0,000 0,01262303 0,02626855 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01262303 0,02625325 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01376311 0,02860772 ! centriole GO:0005814 12 12 0,000 0,01376311 0,02859108 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01376311 0,02857445 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01376311 0,02855785 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01376311 0,02854127 ! bone remodeling GO:0046849 12 12 0,000 0,01376311 0,0285247 ! peroxisomal transport GO:0043574 12 12 0,000 0,01376311 0,02850816 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01376311 0,02849163 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01376311 0,02847512 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01376311 0,02845863 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01376311 0,02844216 ! hippocampus development GO:0021766 12 12 0,000 0,01376311 0,02842571 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 0,01376311 0,02840928 ! T cell selection GO:0045058 16 12 0,000 0,01376311 0,02839287 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01376311 0,02837648 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01376311 0,0283601 ! T-tubule GO:0030315 13 12 0,000 0,01376311 0,02834375 ! methionine metabolic process GO:0006555 13 12 0,000 0,01376311 0,02832741 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01376311 0,02831109 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01376311 0,0282948 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01376311 0,02827852 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01376311 0,02826225 ! mitotic spindle organization GO:0007052 12 12 0,000 0,01376311 0,02824601 ! fear response GO:0042596 12 12 0,000 0,01376311 0,02822979 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01376311 0,02821358 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01376311 0,0281974 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01376311 0,02818123 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01376311 0,02816508 ! axon cargo transport GO:0008088 12 12 0,000 0,01376311 0,02814895 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01376311 0,02813283 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01376311 0,02811674 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 0,01376311 0,02810066 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01376311 0,02808461 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01376311 0,02806857 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01376311 0,02805255 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01376311 0,02803654 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01376311 0,02802056 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01376311 0,02800459 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01376311 0,02798864 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01376311 0,02797271 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01376311 0,0279568 ! cell killing GO:0001906 12 12 0,000 0,01376311 0,02794091 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01376311 0,02792503 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01376311 0,02790918 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01376311 0,02789334 ! detection of bacterium GO:0016045 13 12 0,000 0,01376311 0,02787752 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01376311 0,02786171 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01376311 0,02784593 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01376311 0,02783016 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01376311 0,02781441 ! developmental induction GO:0031128 13 12 0,000 0,01376311 0,02779868 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01376311 0,02778296 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01376311 0,02776727 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01376311 0,02775159 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01376311 0,02773593 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01376311 0,02772028 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01376311 0,02770466 ! thyroid gland development GO:0030878 12 12 0,000 0,01376311 0,02768905 ! non-recombinational repair GO:0000726 12 12 0,000 0,01376311 0,02767346 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01376311 0,02765788 ! lipid localization GO:0010876 12 12 0,000 0,01376311 0,02764233 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01376311 0,02762679 ! response to cAMP GO:0051591 12 12 0,000 0,01376311 0,02761127 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01376311 0,02759577 ! T cell proliferation GO:0042098 17 12 0,000 0,01376311 0,02758028 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01376311 0,02756481 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01376311 0,02754936 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01376311 0,02753393 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01376311 0,02751851 ! drug transport GO:0015893 12 12 0,000 0,01376311 0,02750311 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01376311 0,02748773 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01376311 0,02747236 ! T cell receptor complex GO:0042101 12 12 0,000 0,01376311 0,02745702 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01376311 0,02744169 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 0,01376311 0,02742637 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01376311 0,02741108 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01376311 0,0273958 ! dendritic spine GO:0043197 12 12 0,000 0,01376311 0,02738053 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01376311 0,02736529 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01376311 0,02735006 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01376311 0,02733485 ! vasoconstriction GO:0042310 13 12 0,000 0,01376311 0,02731966 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01376311 0,02730448 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01376311 0,02728932 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01376311 0,02727417 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 0,01376311 0,02725905 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01376311 0,02724394 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01376311 0,02722884 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01376311 0,02721377 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01376311 0,0271987 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01376311 0,02718366 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01376311 0,02716863 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01376311 0,02715362 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01376311 0,02713863 ! protein kinase C binding GO:0005080 13 12 0,000 0,01376311 0,02712365 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01376311 0,02710869 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01376311 0,02709375 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 0,01376311 0,02707882 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01376311 0,02706391 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01376311 0,02704901 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01376311 0,02703414 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01376311 0,02701927 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01376311 0,02700443 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01376311 0,0269896 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01376311 0,02697479 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 0,01376311 0,02695999 ! positive regulation of translation GO:0045727 13 13 0,000 0,01490195 0,02917482 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01490195 0,02915883 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01490195 0,02914286 ! superoxide anion generation GO:0042554 13 13 0,000 0,01490195 0,02912691 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01490195 0,02911098 ! cis-Golgi network GO:0005801 14 13 0,000 0,01490195 0,02909506 ! regulation of S phase GO:0033261 17 13 0,000 0,01490195 0,02907916 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01490195 0,02906328 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01490195 0,02904741 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 0,01490195 0,02903157 ! endothelial cell migration GO:0043542 13 13 0,000 0,01490195 0,02901574 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01490195 0,02899993 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01490195 0,02898413 ! cartilage condensation GO:0001502 14 13 0,000 0,01490195 0,02896835 ! organelle fusion GO:0048284 14 13 0,000 0,01490195 0,02895259 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01490195 0,02893685 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01490195 0,02892112 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01490195 0,02890541 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01490195 0,02888972 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01490195 0,02887404 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01490195 0,02885839 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01490195 0,02884274 ! arginine metabolic process GO:0006525 13 13 0,000 0,01490195 0,02882712 ! WW domain binding GO:0050699 14 13 0,000 0,01490195 0,02881151 ! cholesterol binding GO:0015485 13 13 0,000 0,01490195 0,02879592 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01490195 0,02878035 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01490195 0,02876479 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01490195 0,02874925 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01490195 0,02873373 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01490195 0,02871822 ! regulation of heart rate GO:0002027 14 13 0,000 0,01490195 0,02870273 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01490195 0,02868726 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01490195 0,0286718 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01490195 0,02865636 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01490195 0,02864094 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01490195 0,02862553 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01490195 0,02861014 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01490195 0,02859477 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01490195 0,02857941 ! NADP metabolic process GO:0006739 13 13 0,000 0,01490195 0,02856407 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01490195 0,02854875 ! intestinal absorption GO:0050892 13 13 0,000 0,01490195 0,02853344 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01490195 0,02851815 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01490195 0,02850287 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01490195 0,02848761 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01490195 0,02847237 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01490195 0,02845715 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01490195 0,02844194 ! embryonic placenta development GO:0001892 13 13 0,000 0,01490195 0,02842674 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01490195 0,02841157 ! insulin secretion GO:0030073 13 13 0,000 0,01490195 0,02839641 ! regulation of protein ubiquitination GO:0031396 13 13 0,000 0,01490195 0,02838126 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01490195 0,02836613 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01490195 0,02835102 ! replisome GO:0030894 14 13 0,000 0,01490195 0,02833592 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01490195 0,02832084 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01490195 0,02830578 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01490195 0,02829073 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01490195 0,0282757 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01490195 0,02826068 ! mating GO:0007618 13 13 0,000 0,01490195 0,02824568 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01490195 0,0282307 ! MAP kinase activity GO:0004707 14 13 0,000 0,01490195 0,02821573 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01490195 0,02820078 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01490195 0,02818584 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01490195 0,02817092 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01490195 0,02815601 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01490195 0,02814112 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01490195 0,02812625 ! protein kinase C activity GO:0004697 15 13 0,000 0,01490195 0,02811139 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01490195 0,02809655 ! water transporter activity GO:0005372 13 13 0,000 0,01490195 0,02808172 ! exocrine system development GO:0035272 14 13 0,000 0,01490195 0,02806691 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01490195 0,02805212 ! monoamine transport GO:0015844 13 13 0,000 0,01490195 0,02803734 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01490195 0,02802257 ! embryo implantation GO:0007566 13 13 0,000 0,01490195 0,02800782 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01490195 0,02799309 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01490195 0,02797837 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01490195 0,02796367 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01490195 0,02794898 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01490195 0,02793431 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01490195 0,02791966 ! histone deacetylation GO:0016575 13 13 0,000 0,01490195 0,02790501 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01490195 0,02789039 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01490195 0,02787578 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01490195 0,02786118 ! response to gamma radiation GO:0010332 13 13 0,000 0,01490195 0,02784661 ! sarcomere organization GO:0045214 13 13 0,000 0,01490195 0,02783204 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01490195 0,02781749 ! cAMP binding GO:0030552 13 13 0,000 0,01490195 0,02780296 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01490195 0,02778844 ! cilium assembly GO:0042384 13 13 0,000 0,01490195 0,02777394 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01490195 0,02775945 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01490195 0,02774498 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01490195 0,02773052 ! acrosome reaction GO:0007340 13 13 0,000 0,01490195 0,02771607 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01490195 0,02770165 ! nucleolar part GO:0044452 13 13 0,000 0,01490195 0,02768723 ! axoneme part GO:0044447 13 13 0,000 0,01490195 0,02767284 ! tRNA modification GO:0006400 14 14 0,000 0,01603955 0,02976988 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01603955 0,02975441 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01603955 0,02973897 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01603955 0,02972353 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01603955 0,02970812 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01603955 0,02969271 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01603955 0,02967733 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01603955 0,02966196 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01603955 0,02964661 ! palate development GO:0060021 15 14 0,000 0,01603955 0,02963127 ! centrosome cycle GO:0007098 14 14 0,000 0,01603955 0,02961595 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01603955 0,02960064 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01603955 0,02958535 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01603955 0,02957008 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01603955 0,02955482 ! glycine metabolic process GO:0006544 15 14 0,000 0,01603955 0,02953958 ! plasma membrane organization GO:0007009 14 14 0,000 0,01603955 0,02952435 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01603955 0,02950914 ! response to retinoic acid GO:0032526 14 14 0,000 0,01603955 0,02949395 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01603955 0,02947877 ! lysosomal transport GO:0007041 14 14 0,000 0,01603955 0,0294636 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01603955 0,02944846 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01603955 0,02943332 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01603955 0,02941821 ! bone mineralization GO:0030282 14 14 0,000 0,01603955 0,0294031 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01603955 0,02938802 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 0,000 0,01603955 0,02937295 ! cerebellum development GO:0021549 15 14 0,000 0,01603955 0,02935789 ! G1 phase GO:0051318 14 14 0,000 0,01603955 0,02934285 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01603955 0,02932783 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01603955 0,02931282 ! water homeostasis GO:0030104 14 14 0,000 0,01603955 0,02929782 ! peptide hormone binding GO:0017046 14 14 0,000 0,01603955 0,02928285 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01603955 0,02926788 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01603955 0,02925294 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01603955 0,029238 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01603955 0,02922309 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01603955 0,02920818 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01603955 0,0291933 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01603955 0,02917842 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01603955 0,02916357 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01603955 0,02914873 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01603955 0,0291339 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01603955 0,02911909 ! lactation GO:0007595 15 14 0,000 0,01603955 0,02910429 ! reproductive cellular process GO:0048610 14 14 0,000 0,01603955 0,02908951 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01603955 0,02907474 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01603955 0,02905999 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01603955 0,02904526 ! regulation of B cell proliferation GO:0030888 18 14 0,000 0,01603955 0,02903054 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01603955 0,02901583 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01603955 0,02900114 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01603955 0,02898646 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01603955 0,0289718 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01603955 0,02895715 ! startle response GO:0001964 14 14 0,000 0,01603955 0,02894252 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01603955 0,0289279 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01603955 0,0289133 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01603955 0,02889871 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01603955 0,02888414 ! organic alcohol transport GO:0015850 15 14 0,000 0,01603955 0,02886958 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01603955 0,02885504 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01603955 0,02884051 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01603955 0,02882599 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01603955 0,02881149 ! L-amino acid transport GO:0015807 14 14 0,000 0,01603955 0,02879701 ! microfilament motor activity GO:0000146 14 14 0,000 0,01603955 0,02878254 ! stem cell development GO:0048864 14 14 0,000 0,01603955 0,02876808 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01603955 0,02875364 ! DNA replication initiation GO:0006270 14 14 0,000 0,01603955 0,02873921 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01603955 0,0287248 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01603955 0,0287104 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01603955 0,02869602 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01603955 0,02868165 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01603955 0,02866729 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01603955 0,02865295 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01603955 0,02863862 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01603955 0,02862431 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01603955 0,02861001 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01603955 0,02859573 ! ion gated channel activity GO:0022839 16 14 0,000 0,01603955 0,02858146 ! male genitalia development GO:0030539 14 14 0,000 0,01603955 0,02856721 ! regulation of axon extension GO:0030516 15 14 0,000 0,01603955 0,02855296 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01603955 0,02853874 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01603955 0,02852453 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01603955 0,02851033 ! defense response to virus GO:0051607 19 14 0,000 0,01603955 0,02849614 ! cadherin binding GO:0045296 16 14 0,000 0,01603955 0,02848197 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01717592 0,0304847 ! nuclear replication fork GO:0043596 16 15 0,000 0,01717592 0,03046956 ! skin development GO:0043588 16 15 0,000 0,01717592 0,03045443 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01717592 0,03043931 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01717592 0,03042421 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01717592 0,03040913 ! polysome GO:0005844 16 15 0,000 0,01717592 0,03039406 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01717592 0,03037901 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01717592 0,03036397 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01717592 0,03034894 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01717592 0,03033393 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01717592 0,03031894 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01717592 0,03030396 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01717592 0,03028899 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01717592 0,03027404 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01717592 0,03025911 ! response to vitamin A GO:0033189 15 15 0,000 0,01717592 0,03024419 ! protease binding GO:0002020 16 15 0,000 0,01717592 0,03022928 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01717592 0,03021439 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01717592 0,03019951 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01717592 0,03018465 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01717592 0,03016981 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01717592 0,03015497 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01717592 0,03014015 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01717592 0,03012535 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01717592 0,03011056 ! filopodium GO:0030175 15 15 0,000 0,01717592 0,03009579 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01717592 0,03008103 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01717592 0,03006628 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01717592 0,03005155 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01717592 0,03003683 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01717592 0,03002213 ! SMAD binding GO:0046332 16 15 0,000 0,01717592 0,03000744 ! nerve development GO:0021675 16 15 0,000 0,01717592 0,02999277 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01717592 0,02997811 ! mannose binding GO:0005537 15 15 0,000 0,01717592 0,02996347 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01717592 0,02994884 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01717592 0,02993422 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01717592 0,02991962 ! synaptonemal complex GO:0000795 15 15 0,000 0,01717592 0,02990503 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01717592 0,02989046 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01717592 0,0298759 ! water transport GO:0006833 15 15 0,000 0,01717592 0,02986135 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01717592 0,02984682 ! viral genome replication GO:0019079 15 15 0,000 0,01717592 0,0298323 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01717592 0,0298178 ! inositol metabolic process GO:0006020 15 15 0,000 0,01717592 0,02980331 ! sulfate transport GO:0008272 15 15 0,000 0,01717592 0,02978884 ! protein-lipid complex GO:0032994 15 15 0,000 0,01717592 0,02977438 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01717592 0,02975993 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01717592 0,0297455 ! heart looping GO:0001947 15 15 0,000 0,01717592 0,02973108 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01717592 0,02971667 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01717592 0,02970228 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01717592 0,02968791 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01717592 0,02967354 ! response to osmotic stress GO:0006970 16 15 0,000 0,01717592 0,02965919 ! fructose metabolic process GO:0006000 15 15 0,000 0,01717592 0,02964486 ! ubiquitin binding GO:0043130 15 15 0,000 0,01717592 0,02963054 ! vesicle coating GO:0006901 16 15 0,000 0,01717592 0,02961623 ! DNA integration GO:0015074 16 15 0,000 0,01717592 0,02960194 ! alcohol binding GO:0043178 16 15 0,000 0,01717592 0,02958766 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01717592 0,02957339 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01717592 0,02955914 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01717592 0,0295449 ! genitalia development GO:0048806 15 15 0,000 0,01717592 0,02953068 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01717592 0,02951647 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01717592 0,02950227 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01717592 0,02948808 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01717592 0,02947391 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01717592 0,02945976 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01717592 0,02944561 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01717592 0,02943148 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01717592 0,02941737 ! receptor activator activity GO:0030546 15 15 0,000 0,01717592 0,02940327 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01717592 0,02938918 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01717592 0,0293751 ! histone binding GO:0042393 15 15 0,000 0,01717592 0,02936104 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01717592 0,02934699 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01717592 0,02933296 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01717592 0,02931894 ! drug transporter activity GO:0015238 15 15 0,000 0,01717592 0,02930493 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01717592 0,02929093 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01717592 0,02927695 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01717592 0,02926298 ! peptide hormone processing GO:0016486 17 15 0,000 0,01717592 0,02924903 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01717592 0,02923509 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01717592 0,02922116 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01831105 0,03113751 ! positive regulation of cell size GO:0045793 16 16 0,000 0,01831105 0,03112269 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01831105 0,03110788 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01831105 0,03109309 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01831105 0,03107831 ! response to vitamin GO:0033273 16 16 0,000 0,01831105 0,03106355 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01831105 0,0310488 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01831105 0,03103406 ! kinesin complex GO:0005871 16 16 0,000 0,01831105 0,03101934 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01831105 0,03100463 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01831105 0,03098994 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01831105 0,03097526 ! pituitary gland development GO:0021983 16 16 0,000 0,01831105 0,03096059 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01831105 0,03094594 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01831105 0,0309313 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01831105 0,03091668 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01831105 0,03090207 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01831105 0,03088747 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01831105 0,03087289 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01831105 0,03085832 ! beta-catenin binding GO:0008013 17 16 0,000 0,01831105 0,03084376 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01831105 0,03082922 ! neuron recognition GO:0008038 17 16 0,000 0,01831105 0,03081469 ! oogenesis GO:0048477 19 16 0,000 0,01831105 0,03080017 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01831105 0,03078567 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01831105 0,03077119 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01831105 0,03075671 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01831105 0,03074225 ! biomineral formation GO:0031214 16 16 0,000 0,01831105 0,03072781 ! vitamin transport GO:0051180 16 16 0,000 0,01831105 0,03071337 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01831105 0,03069895 ! organic cation transport GO:0015695 16 16 0,000 0,01831105 0,03068455 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01831105 0,03067016 ! regulation of glucose import GO:0046324 17 16 0,000 0,01831105 0,03065578 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01831105 0,03064141 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01831105 0,03062706 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01831105 0,03061272 ! tRNA binding GO:0000049 16 16 0,000 0,01831105 0,0305984 ! regulation of cell killing GO:0031341 20 16 0,000 0,01831105 0,03058408 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01831105 0,03056979 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01831105 0,0305555 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01831105 0,03054123 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01831105 0,03052697 ! axis specification GO:0009798 16 16 0,000 0,01831105 0,03051273 ! adult walking behavior GO:0007628 17 16 0,000 0,01831105 0,03049849 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01831105 0,03048428 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01831105 0,03047007 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01831105 0,03045588 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01831105 0,0304417 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01831105 0,03042753 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01831105 0,03041338 ! SH2 domain binding GO:0042169 19 16 0,000 0,01831105 0,03039924 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01831105 0,03038512 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01831105 0,030371 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01831105 0,0303569 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01831105 0,03034282 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01831105 0,03032874 ! cellular pigmentation GO:0033059 16 16 0,000 0,01831105 0,03031468 ! mannosidase activity GO:0015923 19 16 0,000 0,01831105 0,03030064 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01831105 0,0302866 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01831105 0,03027258 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01831105 0,03025857 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01831105 0,03024458 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01831105 0,03023059 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01831105 0,03021662 ! axoneme GO:0005930 16 16 0,000 0,01831105 0,03020267 ! anion exchanger activity GO:0015380 18 17 0,000 0,01944495 0,03205814 ! neuron maturation GO:0042551 18 17 0,000 0,01944495 0,03204334 ! metencephalon development GO:0022037 18 17 0,000 0,01944495 0,03202856 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01944495 0,0320138 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01944495 0,03199904 ! hemoglobin complex GO:0005833 18 17 0,000 0,01944495 0,0319843 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01944495 0,03196958 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01944495 0,03195486 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01944495 0,03194017 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01944495 0,03192548 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01944495 0,03191081 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01944495 0,03189615 ! glial cell development GO:0021782 17 17 0,000 0,01944495 0,03188151 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01944495 0,03186688 ! pancreas development GO:0031016 17 17 0,000 0,01944495 0,03185226 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01944495 0,03183765 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01944495 0,03182306 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01944495 0,03180848 ! cerebral cortex development GO:0021987 17 17 0,000 0,01944495 0,03179392 ! cellular response to starvation GO:0009267 18 17 0,000 0,01944495 0,03177937 ! signal sequence binding GO:0005048 17 17 0,000 0,01944495 0,03176483 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01944495 0,03175031 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01944495 0,0317358 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01944495 0,0317213 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01944495 0,03170681 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01944495 0,03169234 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01944495 0,03167788 ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01944495 0,03166344 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01944495 0,03164901 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01944495 0,03163459 ! regulation of protein binding GO:0043393 18 17 0,000 0,01944495 0,03162018 ! recycling endosome GO:0055037 18 17 0,000 0,01944495 0,03160579 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01944495 0,03159141 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01944495 0,03157704 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01944495 0,03156269 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01944495 0,03154835 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01944495 0,03153402 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01944495 0,03151971 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01944495 0,03150541 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01944495 0,03149112 ! steroid catabolic process GO:0006706 17 17 0,000 0,01944495 0,03147685 ! oxygen transport GO:0015671 18 17 0,000 0,01944495 0,03146258 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01944495 0,03144833 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01944495 0,0314341 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01944495 0,03141987 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01944495 0,03140566 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 0,000 0,01944495 0,03139147 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01944495 0,03137728 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01944495 0,03136311 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01944495 0,03134895 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01944495 0,0313348 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01944495 0,03132067 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01944495 0,03130655 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01944495 0,03129244 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01944495 0,03127834 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01944495 0,03126426 ! fucose metabolic process GO:0006004 19 17 0,000 0,01944495 0,03125019 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01944495 0,03123613 ! membrane budding GO:0006900 18 17 0,000 0,01944495 0,03122209 ! AMP binding GO:0016208 17 17 0,000 0,01944495 0,03120805 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01944495 0,03119403 ! body fluid secretion GO:0007589 18 17 0,000 0,01944495 0,03118003 ! response to fungus GO:0009620 17 17 0,000 0,01944495 0,03116603 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01944495 0,03115205 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01944495 0,03113808 ! rRNA binding GO:0019843 17 17 0,000 0,01944495 0,03112412 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01944495 0,03111018 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01944495 0,03109625 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01944495 0,03108233 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01944495 0,03106842 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01944495 0,03105453 ! tissue regeneration GO:0042246 17 17 0,000 0,01944495 0,03104064 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01944495 0,03102677 ! muscle maintenance GO:0046716 18 17 0,000 0,01944495 0,03101292 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01944495 0,03099907 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01944495 0,03098524 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01944495 0,03097142 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01944495 0,03095761 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01944495 0,03094382 ! chaperone binding GO:0051087 18 18 0,000 0,02057762 0,0327317 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02057762 0,03271713 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,02057762 0,03270257 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02057762 0,03268802 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,02057762 0,03267349 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,02057762 0,03265896 ! limbic system development GO:0021761 18 18 0,000 0,02057762 0,03264446 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,02057762 0,03262996 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,02057762 0,03261548 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,02057762 0,03260101 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,02057762 0,03258655 ! lysosome organization GO:0007040 18 18 0,000 0,02057762 0,03257211 ! central nervous system neuron development GO:0021954 19 18 0,000 0,02057762 0,03255767 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,02057762 0,03254325 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,02057762 0,03252885 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,02057762 0,03251446 ! presynaptic membrane GO:0042734 19 18 0,000 0,02057762 0,03250007 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,02057762 0,03248571 ! neural crest cell migration GO:0001755 18 18 0,000 0,02057762 0,03247135 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02057762 0,03245701 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,02057762 0,03244268 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,02057762 0,03242836 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,02057762 0,03241406 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,02057762 0,03239977 ! cell-cell recognition GO:0009988 19 18 0,000 0,02057762 0,03238549 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,02057762 0,03237122 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,02057762 0,03235697 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,02057762 0,03234272 ! actin filament-based movement GO:0030048 18 18 0,000 0,02057762 0,0323285 ! negative regulation of translation GO:0017148 20 18 0,000 0,02057762 0,03231428 ! Rab GTPase binding GO:0017137 18 18 0,000 0,02057762 0,03230007 ! histone deacetylase activity GO:0004407 19 18 0,000 0,02057762 0,03228588 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,02057762 0,0322717 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,02057762 0,03225754 ! glycerol metabolic process GO:0006071 19 18 0,000 0,02057762 0,03224338 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,02057762 0,03222924 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,02057762 0,03221511 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,02057762 0,03220099 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,02057762 0,03218689 ! small conjugating protein binding GO:0032182 18 18 0,000 0,02057762 0,0321728 ! memory GO:0007613 19 18 0,000 0,02057762 0,03215872 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,02057762 0,03214465 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,02057762 0,03213059 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,02057762 0,03211655 ! pigmentation during development GO:0048066 21 18 0,000 0,02057762 0,03210252 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,02057762 0,0320885 ! acetylcholine binding GO:0042166 19 18 0,000 0,02057762 0,0320745 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,02057762 0,0320605 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,02057762 0,03204652 ! neuromuscular junction development GO:0007528 21 18 0,000 0,02057762 0,03203255 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,02057762 0,03201859 ! coreceptor activity GO:0015026 18 18 0,000 0,02057762 0,03200465 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,02057762 0,03199071 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,02057762 0,03197679 ! cytolysis GO:0019835 18 18 0,000 0,02057762 0,03196288 ! phosphate binding GO:0042301 19 18 0,000 0,02057762 0,03194899 ! transport vesicle membrane GO:0030658 21 18 0,000 0,02057762 0,0319351 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,02057762 0,03192123 ! DNA modification GO:0006304 20 18 0,000 0,02057762 0,03190737 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,02057762 0,03189352 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,02057762 0,03187968 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,02057762 0,03186586 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,02057762 0,03185205 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,02057762 0,03183824 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,02057762 0,03182446 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,02057762 0,03181068 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,02057762 0,03179691 ! connexon complex GO:0005922 18 18 0,000 0,02057762 0,03178316 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,02057762 0,03176942 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,02170905 0,03350174 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,02170905 0,03348727 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,02170905 0,03347281 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,02170905 0,03345836 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,02170905 0,03344393 ! cAMP metabolic process GO:0046058 19 19 0,000 0,02170905 0,0334295 ! spindle microtubule GO:0005876 20 19 0,000 0,02170905 0,03341509 ! ovarian follicle development GO:0001541 19 19 0,000 0,02170905 0,0334007 ! retinoid metabolic process GO:0001523 19 19 0,000 0,02170905 0,03338631 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,02170905 0,03337194 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,02170905 0,03335758 ! vacuolar transport GO:0007034 19 19 0,000 0,02170905 0,03334323 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,02170905 0,0333289 GO:0070003|threonine-type peptidase activity, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,02170905 0,03331458 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,02170905 0,03330027 ! cell projection membrane GO:0031253 20 19 0,000 0,02170905 0,03328597 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02170905 0,03327168 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,02170905 0,03325741 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,02170905 0,03324315 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,02170905 0,0332289 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,02170905 0,03321466 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,02170905 0,03320044 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,02170905 0,03318622 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,02170905 0,03317202 ! retinoid binding GO:0005501 19 19 0,000 0,02170905 0,03315784 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,02170905 0,03314366 ! protein stabilization GO:0050821 20 19 0,000 0,02170905 0,0331295 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,02170905 0,03311534 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,02170905 0,0331012 ! microtubule-based transport GO:0010970 19 19 0,000 0,02170905 0,03308708 ! protein complex scaffold GO:0032947 19 19 0,000 0,02170905 0,03307296 ! SNAP receptor activity GO:0005484 21 19 0,000 0,02170905 0,03305886 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02170905 0,03304477 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,02170905 0,03303069 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,02170905 0,03301662 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,02170905 0,03300256 ! glycoprotein binding GO:0001948 23 19 0,000 0,02170905 0,03298852 ! sensory perception of taste GO:0050909 19 19 0,000 0,02170905 0,03297449 ! myoblast differentiation GO:0045445 19 19 0,000 0,02170905 0,03296047 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,02170905 0,03294646 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,02170905 0,03293246 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,02170905 0,03291848 ! cell aging GO:0007569 19 19 0,000 0,02170905 0,03290451 ! stem cell differentiation GO:0048863 19 19 0,000 0,02170905 0,03289055 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,02170905 0,0328766 ! heart process GO:0003015 20 19 0,000 0,02170905 0,03286266 GO:0060047|heart contraction, ! secretory granule membrane GO:0030667 20 19 0,000 0,02170905 0,03284874 ! MHC protein binding GO:0042287 19 19 0,000 0,02170905 0,03283482 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,02170905 0,03282092 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,02170905 0,03280703 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,02170905 0,03279316 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,02170905 0,03277929 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02170905 0,03276544 ! translation elongation factor activity GO:0003746 22 19 0,000 0,02170905 0,03275159 ! insulin receptor binding GO:0005158 20 19 0,000 0,02170905 0,03273776 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,02170905 0,03272394 ! protein secretion GO:0009306 20 20 0,000 0,02283925 0,03441307 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,02283925 0,03439856 ! proteasome core complex GO:0005839 20 20 0,000 0,02283925 0,03438405 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,02283925 0,03436956 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,02283925 0,03435509 ! glutathione transferase activity GO:0004364 20 20 0,000 0,02283925 0,03434062 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,02283925 0,03432617 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,02283925 0,03431173 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,02283925 0,0342973 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,02283925 0,03428288 ! vacuole organization GO:0007033 20 20 0,000 0,02283925 0,03426848 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,02283925 0,03425409 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,02283925 0,0342397 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,02283925 0,03422534 ! regulation of exocytosis GO:0017157 21 20 0,000 0,02283925 0,03421098 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,02283925 0,03419664 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,02283925 0,0341823 ! kinase activator activity GO:0019209 20 20 0,000 0,02283925 0,03416798 ! diencephalon development GO:0021536 20 20 0,000 0,02283925 0,03415368 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,02283925 0,03413938 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,02283925 0,03412509 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,02283925 0,03411082 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,02283925 0,03409656 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,02283925 0,03408231 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,02283925 0,03406808 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,02283925 0,03405385 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,02283925 0,03403964 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,02283925 0,03402544 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,02283925 0,03401125 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,02283925 0,03399707 ! alditol metabolic process GO:0019400 21 20 0,000 0,02283925 0,03398291 ! liver development GO:0001889 20 20 0,000 0,02283925 0,03396875 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,02283925 0,03395461 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,02283925 0,03394048 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,02283925 0,03392636 ! response to alkaloid GO:0043279 22 20 0,000 0,02283925 0,03391226 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,02283925 0,03389816 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,02283925 0,03388408 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,02283925 0,03387001 ! heme metabolic process GO:0042168 22 20 0,000 0,02283925 0,03385595 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,02283925 0,0338419 ! sex determination GO:0007530 20 20 0,000 0,02283925 0,03382786 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,02283925 0,03381384 ! peptide secretion GO:0002790 21 20 0,000 0,02283925 0,03379982 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,02283925 0,03378582 ! interaction with host GO:0051701 24 20 0,000 0,02283925 0,03377183 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,02283925 0,03375785 ! vasodilation GO:0042311 21 20 0,000 0,02283925 0,03374389 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,02283925 0,03372993 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,02283925 0,03371599 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,02283925 0,03370206 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,02283925 0,03368814 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,02283925 0,03367423 ! microvillus GO:0005902 20 20 0,000 0,02283925 0,03366033 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,02283925 0,03364644 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,02283925 0,03363257 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,02396823 0,03528052 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,02396823 0,03526598 ! growth cone GO:0030426 22 21 0,000 0,02396823 0,03525146 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,02396823 0,03523695 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,02396823 0,03522245 ! hormone secretion GO:0046879 22 21 0,000 0,02396823 0,03520796 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,02396823 0,03519348 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,02396823 0,03517902 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,02396823 0,03516456 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,02396823 0,03515012 ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,02396823 0,03513569 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,02396823 0,03512127 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,02396823 0,03510687 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,02396823 0,03509247 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,02396823 0,03507809 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,02396823 0,03506372 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,02396823 0,03504936 ! Golgi stack GO:0005795 25 21 0,000 0,02396823 0,03503502 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,02396823 0,03502068 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,02396823 0,03500636 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,02396823 0,03499205 ! deacetylase activity GO:0019213 22 21 0,000 0,02396823 0,03497775 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,02396823 0,03496346 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,02396823 0,03494918 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02396823 0,03493492 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,02396823 0,03492066 ! pentose metabolic process GO:0019321 22 21 0,000 0,02396823 0,03490642 ! collagen fibril organization GO:0030199 22 21 0,000 0,02396823 0,03489219 ! platelet activation GO:0030168 23 21 0,000 0,02396823 0,03487797 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,02396823 0,03486377 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,02396823 0,03484957 ! glutathione metabolic process GO:0006749 21 21 0,000 0,02396823 0,03483539 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,02396823 0,03482121 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,02396823 0,03480705 ! cyclase activity GO:0009975 21 21 0,000 0,02396823 0,0347929 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,02396823 0,03477877 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,02396823 0,03476464 ! fatty acid binding GO:0005504 21 21 0,000 0,02396823 0,03475053 ! gut development GO:0048565 21 21 0,000 0,02396823 0,03473642 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,02396823 0,03472233 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,02396823 0,03470825 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,02396823 0,03469418 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,02396823 0,03468012 ! positive regulation of fibroblast proliferation GO:0048146 22 21 0,000 0,02396823 0,03466608 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,02396823 0,03465204 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,02396823 0,03463802 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02396823 0,03462401 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,02396823 0,03461001 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,02396823 0,03459602 ! sterol binding GO:0032934 21 21 0,000 0,02396823 0,03458204 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,02396823 0,03456807 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,02396823 0,03455412 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,02396823 0,03454017 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,02396823 0,03452624 ! phosphatase binding GO:0019902 22 21 0,000 0,02396823 0,03451232 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,02396823 0,03449841 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,02396823 0,03448451 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,02396823 0,03447062 ! vesicle targeting GO:0006903 22 21 0,000 0,02396823 0,03445674 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,02396823 0,03444288 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,02396823 0,03442902 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,02396823 0,03441518 ! renal system process GO:0003014 22 21 0,000 0,02396823 0,03440134 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,02396823 0,03438752 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,02396823 0,03437371 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,02396823 0,03435991 ! fatty acid transport GO:0015908 21 21 0,000 0,02396823 0,03434613 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,02396823 0,03433235 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,02396823 0,03431858 ! collagen catabolic process GO:0030574 21 21 0,000 0,02396823 0,03430483 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,02396823 0,03429108 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,02396823 0,03427735 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,02396823 0,03426363 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,02509598 0,03586144 ! site of polarized growth GO:0030427 23 22 0,000 0,02509598 0,03584709 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,02509598 0,03583276 ! leukocyte adhesion GO:0007159 27 22 0,000 0,02509598 0,03581844 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,02509598 0,03580413 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,02509598 0,03578983 ! peroxisome organization GO:0007031 22 22 0,000 0,02509598 0,03577554 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,02509598 0,03576126 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,02509598 0,035747 ! response to starvation GO:0042594 23 22 0,000 0,02509598 0,03573275 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,02509598 0,03571851 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,02509598 0,03570427 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,02509598 0,03569006 ! membrane depolarization GO:0051899 24 22 0,000 0,02509598 0,03567585 ! somitogenesis GO:0001756 23 22 0,000 0,02509598 0,03566165 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,02509598 0,03564747 ! natural killer cell activation GO:0030101 22 22 0,000 0,02509598 0,03563329 ! positive regulation of B cell activation GO:0050871 26 22 0,000 0,02509598 0,03561913 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,02509598 0,03560498 ! basal plasma membrane GO:0009925 22 22 0,000 0,02509598 0,03559084 GO:0045178|basal part of cell, ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,02509598 0,03557671 ! telomere organization GO:0032200 23 22 0,000 0,02509598 0,03556259 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,02509598 0,03554848 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,02509598 0,03553439 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,02509598 0,0355203 ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,02509598 0,03550623 ! initiation of viral infection GO:0019059 22 22 0,000 0,02509598 0,03549217 ! RNA polymerase complex GO:0030880 23 22 0,000 0,02509598 0,03547812 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,02509598 0,03546408 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,02509598 0,03545005 ! response to ethanol GO:0045471 25 22 0,000 0,02509598 0,03543603 ! syntaxin binding GO:0019905 23 22 0,000 0,02509598 0,03542203 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,02509598 0,03540803 ! digestive system process GO:0022600 24 22 0,000 0,02509598 0,03539405 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,02509598 0,03538007 ! autophagy GO:0006914 24 22 0,000 0,02509598 0,03536611 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,02509598 0,03535216 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,02509598 0,03533822 ! negative regulation of phosphorylation GO:0042326 26 22 0,000 0,02509598 0,03532429 ! transaminase activity GO:0008483 23 22 0,000 0,02509598 0,03531037 ! sarcoplasm GO:0016528 23 22 0,000 0,02509598 0,03529647 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,02509598 0,03528257 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,02509598 0,03526869 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,02509598 0,03525481 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,02509598 0,03524095 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,02509598 0,03522709 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,02509598 0,03521325 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,02509598 0,03519942 ! translational initiation GO:0006413 23 23 0,000 0,0262225 0,03676503 ! NF-kappaB binding GO:0051059 23 23 0,000 0,0262225 0,0367506 ! vesicle docking GO:0048278 23 23 0,000 0,0262225 0,03673618 ! muscle myosin complex GO:0005859 25 23 0,000 0,0262225 0,03672178 ! vasculogenesis GO:0001570 25 23 0,000 0,0262225 0,03670738 ! regulation of innate immune response GO:0045088 23 23 0,000 0,0262225 0,036693 ! androgen receptor binding GO:0050681 23 23 0,000 0,0262225 0,03667863 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,0262225 0,03666427 ! sperm motility GO:0030317 23 23 0,000 0,0262225 0,03664992 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,0262225 0,03663558 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,0262225 0,03662125 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,0262225 0,03660693 GO:0051693|actin filament capping, ! negative regulation of phosphorus metabolic process GO:0010563 27 23 0,000 0,0262225 0,03659263 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 0,000 0,0262225 0,03657833 ! regulation of behavior GO:0050795 23 23 0,000 0,0262225 0,03656405 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,0262225 0,03654978 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,0262225 0,03653552 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,0262225 0,03652127 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,0262225 0,03650703 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,0262225 0,0364928 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,0262225 0,03647859 ! pallium development GO:0021543 23 23 0,000 0,0262225 0,03646438 ! GABA receptor activity GO:0016917 24 23 0,000 0,0262225 0,03645019 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,0262225 0,03643601 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,0262225 0,03642183 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,0262225 0,03640767 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,0262225 0,03639352 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,0262225 0,03637938 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,0262225 0,03636526 ! cell surface binding GO:0043498 25 23 0,000 0,0262225 0,03635114 ! collagen binding GO:0005518 27 23 0,000 0,0262225 0,03633703 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,0262225 0,03632294 ! regulation of amine transport GO:0051952 23 23 0,000 0,0262225 0,03630885 ! tissue homeostasis GO:0001894 24 23 0,000 0,0262225 0,03629478 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,0262225 0,03628072 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,0262225 0,03626667 ! gluconeogenesis GO:0006094 24 23 0,000 0,0262225 0,03625263 ! iron ion transport GO:0006826 24 23 0,000 0,0262225 0,0362386 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,0262225 0,03622458 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,0262225 0,03621057 ! molting cycle process GO:0022404 23 23 0,000 0,0262225 0,03619657 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,0262225 0,03618259 ! tube lumen formation GO:0035148 26 23 0,000 0,0262225 0,03616861 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,0262225 0,03615465 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,0262225 0,03614069 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,0262225 0,03612675 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,0262225 0,03611282 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,0262225 0,0360989 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,0262225 0,03608498 ! brush border GO:0005903 25 23 0,000 0,0262225 0,03607108 ! caveola GO:0005901 24 23 0,000 0,0262225 0,03605719 ! gap junction GO:0005921 23 23 0,000 0,0262225 0,03604332 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,02734779 0,03757559 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,02734779 0,03756114 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,02734779 0,0375467 ! protein amino acid acylation GO:0043543 26 24 0,000 0,02734779 0,03753227 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,02734779 0,03751785 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,02734779 0,03750344 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02734779 0,03748905 ! MHC class I protein complex GO:0042612 24 24 0,000 0,02734779 0,03747466 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,02734779 0,03746028 GO:0004950|chemokine receptor activity, ! early endosome membrane GO:0031901 26 24 0,000 0,02734779 0,03744592 ! primary neural tube formation GO:0014020 26 24 0,000 0,02734779 0,03743157 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,02734779 0,03741723 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,02734779 0,0374029 ! lipid kinase activity GO:0001727 26 24 0,000 0,02734779 0,03738858 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,02734779 0,03737427 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,02734779 0,03735997 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,02734779 0,03734568 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,02734779 0,03733141 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,02734779 0,03731714 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,02734779 0,03730289 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,02734779 0,03728865 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,02734779 0,03727441 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,02734779 0,03726019 ! Z disc GO:0030018 27 24 0,000 0,02734779 0,03724598 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,02734779 0,03723178 ! regulation of fibroblast proliferation GO:0048145 25 24 0,000 0,02734779 0,03721759 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,02734779 0,03720341 ! neuron fate commitment GO:0048663 24 24 0,000 0,02734779 0,03718925 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,02734779 0,03717509 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,02734779 0,03716094 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,02734779 0,03714681 ! glucose transport GO:0015758 24 24 0,000 0,02734779 0,03713269 ! dendrite development GO:0016358 26 24 0,000 0,02734779 0,03711857 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,02734779 0,03710447 ! catechol metabolic process GO:0009712 27 24 0,000 0,02734779 0,03709038 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,02734779 0,0370763 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,02734779 0,03706223 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,02734779 0,03704816 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,02734779 0,03703412 ! synaptogenesis GO:0007416 25 24 0,000 0,02734779 0,03702008 ! selenium binding GO:0008430 24 24 0,000 0,02734779 0,03700605 ! leukocyte proliferation GO:0070661 30 24 0,000 0,02734779 0,03699203 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,02734779 0,03697802 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02847186 0,03848335 ! RNA export from nucleus GO:0006405 27 25 0,000 0,02847186 0,03846879 ! phenol metabolic process GO:0018958 28 25 0,000 0,02847186 0,03845424 ! myelination GO:0042552 26 25 0,000 0,02847186 0,03843971 ! hexose transport GO:0008645 25 25 0,000 0,02847186 0,03842518 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02847186 0,03841066 ! PML body GO:0016605 28 25 0,000 0,02847186 0,03839616 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02847186 0,03838166 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02847186 0,03836718 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02847186 0,03835271 ! cell fate determination GO:0001709 25 25 0,000 0,02847186 0,03833824 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02847186 0,03832379 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02847186 0,03830935 ! hormone transport GO:0009914 26 25 0,000 0,02847186 0,03829492 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02847186 0,0382805 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02847186 0,0382661 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02847186 0,0382517 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02847186 0,03823732 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02847186 0,03822294 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02847186 0,03820858 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02847186 0,03819422 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02847186 0,03817988 ! zinc ion transport GO:0006829 26 25 0,000 0,02847186 0,03816555 ! heterochromatin GO:0000792 26 25 0,000 0,02847186 0,03815123 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02847186 0,03813692 ! phototransduction GO:0007602 25 25 0,000 0,02847186 0,03812262 ! spinal cord development GO:0021510 25 25 0,000 0,02847186 0,03810833 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02847186 0,03809405 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02847186 0,03807978 ! response to toxin GO:0009636 25 25 0,000 0,02847186 0,03806553 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02847186 0,03805128 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02847186 0,03803704 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02847186 0,03802282 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02847186 0,03800861 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02847186 0,0379944 ! phospholipid transport GO:0015914 26 25 0,000 0,02847186 0,03798021 ! peptidase activator activity GO:0016504 25 25 0,000 0,02847186 0,03796603 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02847186 0,03795186 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02847186 0,03793769 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,02847186 0,03792354 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02847186 0,0379094 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02847186 0,03789527 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02847186 0,03788116 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02847186 0,03786705 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02847186 0,03785295 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02959471 0,03933112 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02959471 0,03931649 ! regeneration GO:0031099 26 26 0,000 0,02959471 0,03930186 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02959471 0,03928725 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02959471 0,03927265 ! ureteric bud development GO:0001657 26 26 0,000 0,02959471 0,03925807 ! neural crest cell development GO:0014032 26 26 0,000 0,02959471 0,03924349 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02959471 0,03922892 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02959471 0,03921436 ! lipid oxidation GO:0034440 26 26 0,000 0,02959471 0,03919982 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02959471 0,03918528 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02959471 0,03917076 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02959471 0,03915625 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02959471 0,03914175 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02959471 0,03912725 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02959471 0,03911277 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02959471 0,0390983 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02959471 0,03908384 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02959471 0,03906939 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02959471 0,03905496 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02959471 0,03904053 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02959471 0,03902611 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02959471 0,03901171 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02959471 0,03899731 ! chemokine binding GO:0019956 26 26 0,000 0,02959471 0,03898293 ! receptor metabolic process GO:0043112 28 26 0,000 0,02959471 0,03896855 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02959471 0,03895419 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02959471 0,03893984 ! phospholipase C activity GO:0004629 27 26 0,000 0,02959471 0,03892549 ! cellular response to extracellular stimulus GO:0031668 27 26 0,000 0,02959471 0,03891116 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02959471 0,03889684 ! receptor regulator activity GO:0030545 26 26 0,000 0,02959471 0,03888253 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02959471 0,03886823 ! response to heat GO:0009408 26 26 0,000 0,02959471 0,03885394 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02959471 0,03883966 ! mRNA catabolic process GO:0006402 28 27 0,000 0,03071634 0,04029686 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,03071634 0,04028206 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,03071634 0,04026727 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,03071634 0,04025249 ! iron ion homeostasis GO:0055072 27 27 0,000 0,03071634 0,04023773 ! lipoprotein binding GO:0008034 29 27 0,000 0,03071634 0,04022297 ! deaminase activity GO:0019239 27 27 0,000 0,03071634 0,04020823 ! mesoderm formation GO:0001707 28 27 0,000 0,03071634 0,04019349 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,03071634 0,04017877 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,03071634 0,04016406 ! neural tube formation GO:0001841 29 27 0,000 0,03071634 0,04014936 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,03071634 0,04013467 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,03071634 0,04011999 ! integrin complex GO:0008305 28 27 0,000 0,03071634 0,04010532 ! collagen metabolic process GO:0032963 27 27 0,000 0,03071634 0,04009066 ! post-embryonic development GO:0009791 29 27 0,000 0,03071634 0,04007601 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,03071634 0,04006137 ! ovulation cycle process GO:0022602 27 27 0,000 0,03071634 0,04004675 ! SNARE binding GO:0000149 28 27 0,000 0,03071634 0,04003213 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,03071634 0,04001753 ! spindle pole GO:0000922 28 27 0,000 0,03071634 0,04000293 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,03071634 0,03998835 ! trans-Golgi network GO:0005802 29 28 0,000 0,03183674 0,04143186 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,03183674 0,04141676 ! cholesterol transport GO:0030301 28 28 0,000 0,03183674 0,04140168 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,03183674 0,04138661 ! dynein complex GO:0030286 29 28 0,000 0,03183674 0,04137155 ! formation of primary germ layer GO:0001704 29 28 0,000 0,03183674 0,0413565 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,03183674 0,04134146 ! ovulation cycle GO:0042698 28 28 0,000 0,03183674 0,04132643 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,03183674 0,04131142 ! cofactor catabolic process GO:0051187 30 28 0,000 0,03183674 0,04129641 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,03183674 0,04128141 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,03183674 0,04126643 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,03183674 0,04125146 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,03183674 0,04123649 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,03183674 0,04122154 ! membrane docking GO:0022406 28 28 0,000 0,03183674 0,0412066 ! sister chromatid segregation GO:0000819 28 28 0,000 0,03183674 0,04119167 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,03183674 0,04117675 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,03183674 0,04116184 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,03183674 0,04114695 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,03183674 0,04113206 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,03183674 0,04111718 ! caspase regulator activity GO:0043028 28 28 0,000 0,03183674 0,04110232 ! ensheathment of neurons GO:0007272 29 28 0,000 0,03183674 0,04108747 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,03183674 0,04107262 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,03183674 0,04105779 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,03183674 0,04104297 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,03183674 0,04102815 ! glycogen metabolic process GO:0005977 29 28 0,000 0,03183674 0,04101335 ! RNA helicase activity GO:0003724 28 28 0,000 0,03183674 0,04099856 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,03183674 0,04098378 ! protein kinase inhibitor activity GO:0004860 28 28 0,000 0,03183674 0,04096901 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,03183674 0,04095426 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,03295593 0,04237869 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,03295593 0,04236344 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,03295593 0,0423482 ! scavenger receptor activity GO:0005044 30 29 0,000 0,03295593 0,04233296 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,03295593 0,04231774 ! male gonad development GO:0008584 29 29 0,000 0,03295593 0,04230253 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,03295593 0,04228733 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,03295593 0,04227214 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,03295593 0,04225696 ! endocytic vesicle GO:0030139 29 29 0,000 0,03295593 0,04224179 ! Rho GTPase binding GO:0017048 32 29 0,000 0,03295593 0,04222664 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,03295593 0,04221149 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,03295593 0,04219636 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,03295593 0,04218123 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,03295593 0,04216612 ! glucan metabolic process GO:0044042 30 29 0,000 0,03295593 0,04215102 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,03295593 0,04213592 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,03295593 0,04212084 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,03295593 0,04210577 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,03295593 0,04209071 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,03295593 0,04207567 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,03295593 0,04206063 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,03295593 0,0420456 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,03295593 0,04203058 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,03295593 0,04201558 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,03295593 0,04200058 ! detection of visible light GO:0009584 29 29 0,000 0,03295593 0,0419856 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,03295593 0,04197063 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,03295593 0,04195566 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03295593 0,04194071 ! gene silencing GO:0016458 29 29 0,000 0,03295593 0,04192577 ! hormone binding GO:0042562 30 30 0,000 0,0340739 0,04333259 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,0340739 0,04331716 ! acrosomal vesicle GO:0001669 32 30 0,000 0,0340739 0,04330175 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,0340739 0,04328634 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,0340739 0,04327095 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,0340739 0,04325557 ! glutamate receptor activity GO:0008066 33 30 0,000 0,0340739 0,04324019 ! kinase inhibitor activity GO:0019210 30 30 0,000 0,0340739 0,04322483 ! ceramide metabolic process GO:0006672 30 30 0,000 0,0340739 0,04320948 ! cell fate specification GO:0001708 31 30 0,000 0,0340739 0,04319414 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,0340739 0,04317882 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,0340739 0,0431635 ! PDZ domain binding GO:0030165 32 30 0,000 0,0340739 0,04314819 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,0340739 0,0431329 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,0340739 0,04311761 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,0340739 0,04310234 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,0340739 0,04308708 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,0340739 0,04307183 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,0340739 0,04305658 ! drug binding GO:0008144 30 30 0,000 0,0340739 0,04304135 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,0340739 0,04302613 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,0340739 0,04301092 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,0340739 0,04299573 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,0340739 0,04298054 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,0340739 0,04296536 ! aminopeptidase activity GO:0004177 32 30 0,000 0,0340739 0,0429502 ! detection of light stimulus GO:0009583 30 30 0,000 0,0340739 0,04293504 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,0340739 0,0429199 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,0340739 0,04290476 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,0340739 0,04288964 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,03519066 0,04427972 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03519066 0,04426412 ! spliceosome assembly GO:0000245 32 31 0,000 0,03519066 0,04424853 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,03519066 0,04423296 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,03519066 0,04421739 ! NAD or NADH binding GO:0051287 31 31 0,000 0,03519066 0,04420184 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,03519066 0,0441863 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,03519066 0,04417077 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,03519066 0,04415525 ! placenta development GO:0001890 31 31 0,000 0,03519066 0,04413974 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,03519066 0,04412424 ! regulation of pH GO:0006885 31 31 0,000 0,03519066 0,04410875 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,03519066 0,04409327 ! acute-phase response GO:0006953 32 31 0,000 0,03519066 0,04407781 ! peptide transport GO:0015833 32 31 0,000 0,03519066 0,04406235 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,03519066 0,04404691 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,03519066 0,04403148 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,03519066 0,04401605 ! regulation of protein stability GO:0031647 32 31 0,000 0,03519066 0,04400064 ! sarcolemma GO:0042383 33 31 0,000 0,03519066 0,04398524 ! vesicle localization GO:0051648 32 31 0,000 0,03519066 0,04396985 ! microtubule organizing center part GO:0044450 34 31 0,000 0,03519066 0,04395447 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,03630619 0,04533197 ! DNA helicase activity GO:0003678 34 32 0,000 0,03630619 0,04531612 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,03630619 0,04530029 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,03630619 0,04528446 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,03630619 0,04526865 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,03630619 0,04525285 ! late endosome membrane GO:0031902 32 32 0,000 0,03630619 0,04523706 ! positive regulation of cell development GO:0010720 33 32 0,000 0,03630619 0,04522128 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,03630619 0,04520552 ! hindbrain development GO:0030902 35 32 0,000 0,03630619 0,04518976 ! aerobic respiration GO:0009060 32 32 0,000 0,03630619 0,04517401 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,03630619 0,04515828 ! regulation of B cell activation GO:0050864 36 32 0,000 0,03630619 0,04514256 ! regulation of muscle development GO:0048634 33 32 0,000 0,03630619 0,04512684 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,03630619 0,04511114 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,03630619 0,04509545 ! response to ionizing radiation GO:0010212 33 32 0,000 0,03630619 0,04507977 ! flagellum GO:0019861 32 32 0,000 0,03630619 0,0450641 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,03630619 0,04504844 ! I band GO:0031674 35 32 0,000 0,03630619 0,0450328 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,03630619 0,04501716 ! adult locomotory behavior GO:0008344 33 32 0,000 0,03630619 0,04500153 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,03630619 0,04498592 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,03742052 0,04635056 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,03742052 0,04633449 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,03742052 0,04631843 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,03742052 0,04630238 ! negative regulation of binding GO:0051100 34 33 0,000 0,03742052 0,04628634 ! organelle envelope lumen GO:0031970 34 33 0,000 0,03742052 0,04627032 ! protein targeting to membrane GO:0006612 35 33 0,000 0,03742052 0,0462543 ! vesicle coat GO:0030120 36 33 0,000 0,03742052 0,04623829 ! eye morphogenesis GO:0048592 38 33 0,000 0,03742052 0,0462223 ! embryonic organ development GO:0048568 36 33 0,000 0,03742052 0,04620632 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,03742052 0,04619035 ! glial cell differentiation GO:0010001 33 33 0,000 0,03742052 0,04617439 ! cell junction organization GO:0034330 35 33 0,000 0,03742052 0,04615844 ! tissue remodeling GO:0048771 35 33 0,000 0,03742052 0,0461425 ! segmentation GO:0035282 34 33 0,000 0,03742052 0,04612657 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,03742052 0,04611065 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,03742052 0,04609475 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,03742052 0,04607885 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03742052 0,04606297 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,03742052 0,0460471 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,03742052 0,04603123 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,03742052 0,04601538 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,03742052 0,04599954 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,03853363 0,04735155 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,03853363 0,04733526 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,03853363 0,04731898 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,03853363 0,04730271 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,03853363 0,04728646 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,03853363 0,04727021 ! telencephalon development GO:0021537 34 34 0,000 0,03853363 0,04725398 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,03853363 0,04723776 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,03853363 0,04722155 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,03853363 0,04720535 ! collagen GO:0005581 35 34 0,000 0,03853363 0,04718916 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,03853363 0,04717298 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,03853363 0,04715682 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,03853363 0,04714066 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,03853363 0,04712452 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,03853363 0,04710839 ! spermatid development GO:0007286 34 34 0,000 0,03853363 0,04709226 ! BMP signaling pathway GO:0030509 35 34 0,000 0,03853363 0,04707615 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,03853363 0,04706005 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,03964553 0,04840143 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,03964553 0,04838489 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,03964553 0,04836836 ! vesicle lumen GO:0031983 37 35 0,000 0,03964553 0,04835184 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,03964553 0,04833533 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,03964553 0,04831884 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,03964553 0,04830235 ! cytokine production GO:0001816 35 35 0,000 0,03964553 0,04828588 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,03964553 0,04826941 ! embryonic pattern specification GO:0009880 36 35 0,000 0,03964553 0,04825296 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,03964553 0,04823652 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,03964553 0,04822009 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,03964553 0,04820367 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,03964553 0,04818727 ! phagocytosis GO:0006909 37 35 0,000 0,03964553 0,04817087 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,03964553 0,04815449 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,03964553 0,04813811 ! ion transmembrane transport GO:0034220 35 35 0,000 0,03964553 0,04812175 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,03964553 0,0481054 ! oxygen binding GO:0019825 36 35 0,000 0,03964553 0,04808906 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,03964553 0,04807273 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,03964553 0,04805641 ! peripheral nervous system development GO:0007422 37 35 0,000 0,03964553 0,0480401 ! female gamete generation GO:0007292 38 35 0,000 0,03964553 0,04802381 ! polyol metabolic process GO:0019751 36 35 0,000 0,03964553 0,04800752 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,04075622 0,04933575 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,04075622 0,04931903 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,04075622 0,04930232 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,04075622 0,04928563 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,04075622 0,04926894 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,04075622 0,04925227 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,04075622 0,04923561 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,04075622 0,04921896 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,04075622 0,04920232 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,04075622 0,04918569 ! spermatid differentiation GO:0048515 36 36 0,000 0,04075622 0,04916907 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,04075622 0,04915247 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,04075622 0,04913587 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,04075622 0,04911929 ! neuropeptide binding GO:0042923 36 36 0,000 0,04075622 0,04910272 ! organic anion transport GO:0015711 37 36 0,000 0,04075622 0,04908616 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,04075622 0,04906961 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,04075622 0,04905307 ! antigen binding GO:0003823 36 36 0,000 0,04075622 0,04903654 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,04075622 0,04902003 ! cytokinesis GO:0000910 40 36 0,000 0,04075622 0,04900352 ! coated pit GO:0005905 42 36 0,000 0,04075622 0,04898703 ! positive regulation of leukocyte proliferation GO:0070665 40 36 0,000 0,04075622 0,04897054 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,0418657 0,05028672 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,0418657 0,05026981 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,0418657 0,05025291 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,0418657 0,05023603 ! biopolymer methylation GO:0043414 42 37 0,000 0,0418657 0,05021915 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,0418657 0,05020229 ! protein homooligomerization GO:0051260 38 37 0,000 0,0418657 0,05018544 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,0418657 0,0501686 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,0418657 0,05015177 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,0418657 0,05013495 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,0418657 0,05011814 ! amino acid binding GO:0016597 40 37 0,000 0,0418657 0,05010135 ! maintenance of protein location GO:0045185 38 37 0,000 0,0418657 0,05008456 ! maintenance of location in cell GO:0051651 38 37 0,000 0,0418657 0,05006779 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,0418657 0,05005103 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,0418657 0,05003428 ! ear morphogenesis GO:0042471 39 38 0,000 0,04297397 0,0513416 ! odontogenesis GO:0042476 40 38 0,000 0,04297397 0,05132443 ! organic ether metabolic process GO:0018904 39 38 0,000 0,04297397 0,05130727 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,04297397 0,05129013 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,04297397 0,05127299 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,04297397 0,05125586 ! B cell differentiation GO:0030183 40 38 0,000 0,04297397 0,05123875 ! clathrin coat GO:0030118 43 38 0,000 0,04297397 0,05122165 ! regulation of endocytosis GO:0030100 39 38 0,000 0,04297397 0,05120456 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,04297397 0,05118748 ! cell growth GO:0016049 40 38 0,000 0,04297397 0,05117041 ! positive regulation of defense response GO:0031349 38 38 0,000 0,04297397 0,05115335 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,04297397 0,05113631 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,04297397 0,05111927 ! learning GO:0007612 42 38 0,000 0,04297397 0,05110225 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,04297397 0,05108524 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,04297397 0,05106824 ! endosome transport GO:0016197 40 38 0,000 0,04297397 0,05105125 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,04297397 0,05103427 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,04297397 0,05101731 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,04297397 0,05100035 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,04297397 0,05098341 ! pigment metabolic process GO:0042440 42 38 0,000 0,04297397 0,05096647 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,04297397 0,05094955 ! RNA modification GO:0009451 39 38 0,000 0,04297397 0,05093264 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,04408104 0,0522274 ! Notch signaling pathway GO:0007219 41 39 0,000 0,04408104 0,05221008 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,04408104 0,05219277 ! keratin filament GO:0045095 41 39 0,000 0,04408104 0,05217547 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,04408104 0,05215818 ! peroxisomal membrane GO:0005778 40 39 0,000 0,04408104 0,0521409 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,04408104 0,05212364 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,04408104 0,05210638 ! regulation of protein secretion GO:0050708 41 39 0,000 0,04408104 0,05208914 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,04408104 0,05207191 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,04408104 0,05205469 ! viral infectious cycle GO:0019058 39 39 0,000 0,04408104 0,05203748 ! mammary gland development GO:0030879 41 39 0,000 0,04408104 0,05202029 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,04408104 0,0520031 ! amine receptor activity GO:0008227 41 39 0,000 0,04408104 0,05198593 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,04408104 0,05196876 ! monosaccharide binding GO:0048029 39 39 0,000 0,04408104 0,05195161 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,04408104 0,05193447 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,0451869 0,05321979 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,0451869 0,05320225 ! peptide metabolic process GO:0006518 41 40 0,000 0,0451869 0,05318471 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,0451869 0,05316719 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,0451869 0,05314968 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,0451869 0,05313218 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,0451869 0,05311469 ! neuron migration GO:0001764 42 40 0,000 0,0451869 0,05309721 ! nuclear export GO:0051168 42 40 0,000 0,0451869 0,05307974 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,0451869 0,05306229 ! structural constituent of muscle GO:0008307 43 40 0,000 0,0451869 0,05304484 ! gliogenesis GO:0042063 40 40 0,000 0,0451869 0,05302741 ! feeding behavior GO:0007631 40 40 0,000 0,0451869 0,05300999 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,0451869 0,05299258 ! nucleus organization GO:0006997 40 40 0,000 0,0451869 0,05297519 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,0451869 0,0529578 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,0451869 0,05294043 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,0451869 0,05292306 ! chromatin remodeling GO:0006338 43 40 0,000 0,0451869 0,05290571 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,04629156 0,0541813 ! positive regulation of binding GO:0051099 42 41 0,000 0,04629156 0,05416355 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,04629156 0,05414581 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,04629156 0,05412808 ! regulation of translational initiation GO:0006446 41 41 0,000 0,04629156 0,05411036 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,04629156 0,05409265 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,04629156 0,05407496 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,04629156 0,05405727 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,04629156 0,0540396 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,04629156 0,05402194 ! hydro-lyase activity GO:0016836 44 41 0,000 0,04629156 0,05400429 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,04629156 0,05398666 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,04629156 0,05396903 ! metal cluster binding GO:0051540 43 41 0,000 0,04629156 0,05395142 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,04629156 0,05393382 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,04629156 0,05391622 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,04629156 0,05389865 ! RNA catabolic process GO:0006401 44 42 0,000 0,04739501 0,05516544 ! organellar ribosome GO:0000313 43 42 0,000 0,04739501 0,05514747 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,04739501 0,0551295 ! MHC protein complex GO:0042611 42 42 0,000 0,04739501 0,05511155 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,04739501 0,05509361 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,04739501 0,05507568 ! positive regulation of growth GO:0045927 42 42 0,000 0,04739501 0,05505777 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,04739501 0,05503986 ! chemokine activity GO:0008009 42 42 0,000 0,04739501 0,05502197 ! pigmentation GO:0043473 46 42 0,000 0,04739501 0,05500409 ! developmental growth GO:0048589 42 42 0,000 0,04739501 0,05498622 ! methylation GO:0032259 47 42 0,000 0,04739501 0,05496836 ! glycolysis GO:0006096 42 42 0,000 0,04739501 0,05495051 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,04739501 0,05493268 ! regulation of tube size GO:0035150 44 42 0,000 0,04739501 0,05491485 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,04739501 0,05489704 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,04739501 0,05487924 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,04739501 0,05486145 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,04849726 0,05611916 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,04849726 0,05610098 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,04849726 0,05608281 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,04849726 0,05606466 ! sulfotransferase activity GO:0008146 44 43 0,000 0,04849726 0,05604651 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,04849726 0,05602838 ! channel regulator activity GO:0016247 46 43 0,000 0,04849726 0,05601026 ! histone modification GO:0016570 44 43 0,000 0,04849726 0,05599215 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,04849726 0,05597405 ! synaptosome GO:0019717 47 43 0,000 0,04849726 0,05595597 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,04959831 0,05720787 ! platelet alpha granule GO:0031091 46 44 0,000 0,04959831 0,0571894 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,04959831 0,05717094 ! regulation of ossification GO:0030278 48 44 0,000 0,04959831 0,05715249 ! cell recognition GO:0008037 46 44 0,000 0,04959831 0,05713406 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,04959831 0,05711563 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,04959831 0,05709722 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,04959831 0,05707882 ! cellular component disassembly GO:0022411 45 44 0,000 0,04959831 0,05706043 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,04959831 0,05704205 ! regulation of ion transport GO:0043269 47 44 0,000 0,04959831 0,05702369 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,04959831 0,05700533 ! inner ear development GO:0048839 46 44 0,000 0,04959831 0,05698699 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,04959831 0,05696866 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,04959831 0,05695035 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,04959831 0,05693204 ! chemokine receptor binding GO:0042379 44 44 0,000 0,04959831 0,05691375 ! regulation of mast cell proliferation GO:0070666 48 44 0,000 0,04959831 0,05689546 ! regulation of action potential GO:0001508 50 45 0,000 0,05069816 0,05813845 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,05069816 0,05811979 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,05069816 0,05810114 ! response to temperature stimulus GO:0009266 45 45 0,000 0,05069816 0,0580825 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,05069816 0,05806387 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,05069816 0,05804525 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,05069816 0,05802665 ! excretion GO:0007588 46 45 0,000 0,05069816 0,05800806 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,05069816 0,05798948 ! JNK cascade GO:0007254 45 45 0,000 0,05069816 0,05797091 ! regulation of cell shape GO:0008360 46 45 0,000 0,05069816 0,05795235 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,05069816 0,05793381 ! microbody part GO:0044438 46 45 0,000 0,05069816 0,05791527 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,05179682 0,0591514 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,05179682 0,05913249 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! microtubule binding GO:0008017 49 46 0,000 0,05179682 0,0591136 ! regulation of inflammatory response GO:0050727 46 46 0,000 0,05179682 0,05909471 ! transport vesicle GO:0030133 49 46 0,000 0,05179682 0,05907584 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,05179682 0,05905697 ! synapse organization GO:0050808 51 46 0,000 0,05179682 0,05903812 ! nuclear matrix GO:0016363 49 46 0,000 0,05179682 0,05901929 ! striated muscle contraction GO:0006941 49 46 0,000 0,05179682 0,05900046 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,05179682 0,05898165 ! antioxidant activity GO:0016209 47 46 0,000 0,05179682 0,05896284 ! activation of caspase activity GO:0006919 49 46 0,000 0,05179682 0,05894405 ! male sex differentiation GO:0046661 46 46 0,000 0,05179682 0,05892528 ! coated vesicle membrane GO:0030662 49 46 0,000 0,05179682 0,05890651 ! covalent chromatin modification GO:0016569 47 46 0,000 0,05179682 0,05888776 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,05179682 0,05886901 ! regulation of leukocyte proliferation GO:0070663 50 46 0,000 0,05179682 0,05885028 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,05289428 0,06007807 ! carbohydrate transport GO:0008643 47 47 0,000 0,05289428 0,06005897 ! proteasome complex GO:0000502 48 47 0,000 0,05289428 0,06003988 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,05289428 0,0600208 ! vesicle organization GO:0016050 50 47 0,000 0,05289428 0,06000173 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,05289428 0,05998268 ! cell cortex part GO:0044448 51 47 0,000 0,05289428 0,05996364 ! lipid modification GO:0030258 49 48 0,000 0,05399054 0,06118699 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,05399054 0,06116758 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,05399054 0,06114818 ! mitochondrial transport GO:0006839 49 48 0,000 0,05399054 0,06112879 ! viral reproductive process GO:0022415 52 48 0,000 0,05399054 0,06110942 ! leukocyte migration GO:0050900 49 48 0,000 0,05399054 0,06109005 ! neuromuscular process GO:0050905 49 48 0,000 0,05399054 0,0610707 ! gastrulation GO:0007369 50 48 0,000 0,05399054 0,06105137 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,05399054 0,06103204 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,05399054 0,06101273 ! protein N-terminus binding GO:0047485 51 48 0,000 0,05399054 0,06099342 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,05508561 0,06221085 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,05508561 0,06219118 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,05508561 0,06217152 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,05508561 0,06215188 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,05508561 0,06213225 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,05508561 0,06211263 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,05508561 0,06209302 ! nucleosome GO:0000786 49 49 0,000 0,05508561 0,06207343 ! kinetochore GO:0000776 50 49 0,000 0,05508561 0,06205385 ! membrane fusion GO:0006944 51 49 0,000 0,05508561 0,06203428 ! endocrine system development GO:0035270 49 49 0,000 0,05508561 0,06201472 ! RNA elongation GO:0006354 51 49 0,000 0,05508561 0,06199518 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,05617948 0,06320634 ! basement membrane GO:0005604 51 50 0,000 0,05617948 0,06318643 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,05617948 0,06316654 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,05617948 0,06314666 ! maintenance of location GO:0051235 51 50 0,000 0,05617948 0,06312679 ! cell redox homeostasis GO:0045454 51 50 0,000 0,05617948 0,06310693 ! integrin binding GO:0005178 53 50 0,000 0,05617948 0,06308708 ! amino acid activation GO:0043038 50 50 0,000 0,05617948 0,06306725 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,05617948 0,06304743 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,05727216 0,0642535 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,05727216 0,06423332 ! late endosome GO:0005770 51 51 0,000 0,05727216 0,06421315 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,05727216 0,064193 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,05727216 0,06417286 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,05727216 0,06415273 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,05727216 0,06413261 ! heart morphogenesis GO:0003007 54 51 0,000 0,05727216 0,06411251 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,05727216 0,06409241 ! antiporter activity GO:0015297 52 51 0,000 0,05727216 0,06407233 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,05836365 0,06527298 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,05836365 0,06525254 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,05836365 0,06523212 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,05836365 0,06521171 ! cell maturation GO:0048469 55 52 0,000 0,05836365 0,06519131 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,05836365 0,06517092 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,05836365 0,06515055 ! chloride transport GO:0006821 53 52 0,000 0,05836365 0,06513019 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,05836365 0,06510984 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 56 52 0,000 0,05836365 0,06508951 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,05836365 0,06506919 ! glucose catabolic process GO:0006007 52 52 0,000 0,05836365 0,06504888 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,05836365 0,06502858 ! small ribosomal subunit GO:0015935 52 52 0,000 0,05836365 0,0650083 ! cytokine receptor activity GO:0004896 53 52 0,000 0,05836365 0,06498803 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,05945396 0,06618145 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,05945396 0,06616082 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,05945396 0,06614021 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,05945396 0,06611961 ! synaptic vesicle GO:0008021 57 53 0,000 0,05945396 0,06609903 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,05945396 0,06607846 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,05945396 0,0660579 ! cell projection assembly GO:0030031 56 53 0,000 0,05945396 0,06603735 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,05945396 0,06601682 ! proton transport GO:0015992 53 53 0,000 0,05945396 0,06599629 ! mRNA binding GO:0003729 55 53 0,000 0,05945396 0,06597579 ! single fertilization GO:0007338 55 53 0,000 0,05945396 0,06595529 ! axon GO:0030424 58 54 0,000 0,06054307 0,06714264 ! heat shock protein binding GO:0031072 54 54 0,000 0,06054307 0,0671218 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,06054307 0,06710096 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,06054307 0,06708014 ! tRNA processing GO:0008033 55 54 0,000 0,06054307 0,06705934 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,06054307 0,06703854 ! DNA catabolic process GO:0006308 55 54 0,000 0,06054307 0,06701776 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,06054307 0,066997 ! hydrogen transport GO:0006818 55 55 0,000 0,061631 0,06817977 ! large ribosomal subunit GO:0015934 56 55 0,000 0,061631 0,06815865 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,061631 0,06813755 ! positive regulation of secretion GO:0051047 60 56 0,000 0,06271774 0,06931756 ! regulation of mitosis GO:0007088 56 56 0,000 0,06271774 0,06929612 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,06271774 0,06927468 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,06271774 0,06925326 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,06271774 0,06923185 ! cartilage development GO:0051216 59 56 0,000 0,06271774 0,06921046 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,06271774 0,06918908 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,06271774 0,06916771 ! mesoderm development GO:0007498 57 56 0,000 0,06271774 0,06914636 ! camera-type eye development GO:0043010 59 56 0,000 0,06271774 0,06912501 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,0638033 0,07029977 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,0638033 0,07027809 ! chromosome segregation GO:0007059 59 57 0,000 0,0638033 0,07025642 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,0638033 0,07023476 ! kidney development GO:0001822 60 57 0,000 0,0638033 0,07021312 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,0638033 0,07019149 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,0638033 0,07016987 ! adult behavior GO:0030534 60 57 0,000 0,0638033 0,07014827 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,0638033 0,07012667 ! myosin complex GO:0016459 59 57 0,000 0,0638033 0,0701051 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,06488767 0,07127464 ! lysosomal membrane GO:0005765 59 58 0,000 0,06488767 0,07125273 ! extracellular matrix organization GO:0030198 59 58 0,000 0,06488767 0,07123082 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,06488767 0,07120893 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,06488767 0,07118705 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,06488767 0,07116519 ! detection of external stimulus GO:0009581 59 58 0,000 0,06488767 0,07114334 ! secondary metabolic process GO:0019748 59 58 0,000 0,06488767 0,0711215 ! translation initiation factor activity GO:0003743 58 58 0,000 0,06488767 0,07109968 ! dendrite GO:0030425 61 59 0,000 0,06597086 0,0722644 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,06597086 0,07224224 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,06597086 0,07222009 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 62 59 0,000 0,06597086 0,07219796 ! copper ion binding GO:0005507 61 59 0,000 0,06597086 0,07217584 ! activation of immune response GO:0002253 68 59 0,000 0,06597086 0,07215373 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,06597086 0,07213164 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,06597086 0,07210956 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,06597086 0,0720875 ! cell soma GO:0043025 63 59 0,000 0,06597086 0,07206544 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,06597086 0,07204341 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,06705287 0,07320263 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,06705287 0,07318026 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,06705287 0,0731579 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,06705287 0,07313555 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,06705287 0,07311322 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,06705287 0,0730909 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,06705287 0,0730686 ! chloride channel activity GO:0005254 61 60 0,000 0,06705287 0,07304631 ! negative regulation of protein kinase activity GO:0006469 67 61 0,000 0,0681337 0,07420111 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,0681337 0,07417849 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,0681337 0,07415588 ! fertilization GO:0009566 64 61 0,000 0,0681337 0,07413328 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,0681337 0,0741107 ! gonad development GO:0008406 61 61 0,000 0,0681337 0,07408814 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,0681337 0,07406558 ! regulation of immune effector process GO:0002697 65 61 0,000 0,0681337 0,07404304 ! amine catabolic process GO:0009310 68 62 0,000 0,06921335 0,07519345 ! coated membrane GO:0048475 67 62 0,000 0,06921335 0,07517058 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,06921335 0,07514773 ! negative regulation of kinase activity GO:0033673 68 62 0,000 0,06921335 0,07512489 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,06921335 0,07510206 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,06921335 0,07507925 ! germ cell development GO:0007281 62 62 0,000 0,06921335 0,07505645 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,06921335 0,07503366 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,07029182 0,0761797 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,07029182 0,07615659 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,07029182 0,07613349 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,07029182 0,0761104 ! transition metal ion transport GO:0000041 65 63 0,000 0,07029182 0,07608733 ! appendage morphogenesis GO:0035107 67 63 0,000 0,07029182 0,07606427 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,07029182 0,07604123 ! cellular defense response GO:0006968 64 63 0,000 0,07029182 0,0760182 ! antigen processing and presentation GO:0019882 64 63 0,000 0,07029182 0,07599519 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,07029182 0,07597219 ! microtubule motor activity GO:0003777 67 63 0,000 0,07029182 0,0759492 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,07029182 0,07592623 ! organelle localization GO:0051640 66 63 0,000 0,07029182 0,07590327 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,07136912 0,07704327 ! lung development GO:0030324 65 64 0,000 0,07136912 0,07701999 ! respiratory chain GO:0070469 66 64 0,000 0,07136912 0,07699672 ! developmental maturation GO:0021700 67 64 0,000 0,07136912 0,07697346 ! amino acid transport GO:0006865 64 64 0,000 0,07136912 0,07695022 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,07136912 0,076927 ! anion channel activity GO:0005253 65 64 0,000 0,07136912 0,07690378 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,07244525 0,07803981 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,07244525 0,07801628 ! negative regulation of cell growth GO:0030308 68 65 0,000 0,07244525 0,07799276 ! nuclear pore GO:0005643 69 65 0,000 0,07244525 0,07796925 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,07244525 0,07794576 ! negative regulation of transferase activity GO:0051348 71 65 0,000 0,07244525 0,07792228 ! rhythmic process GO:0048511 66 65 0,000 0,07244525 0,07789882 ! regulation of lipase activity GO:0060191 67 65 0,000 0,07244525 0,07787537 ! appendage development GO:0048736 69 65 0,000 0,07244525 0,07785193 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,07244525 0,07782851 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,07244525 0,0778051 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,0735202 0,07893584 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,0735202 0,07891212 ! urogenital system development GO:0001655 69 66 0,000 0,0735202 0,07888841 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,0735202 0,07886471 ! diacylglycerol binding GO:0019992 71 66 0,000 0,0735202 0,07884103 ! amine binding GO:0043176 70 66 0,000 0,0735202 0,07881736 ! response to nutrient GO:0007584 67 66 0,000 0,0735202 0,0787937 ! acetyltransferase activity GO:0016407 68 66 0,000 0,0735202 0,07877006 ! negative regulation of cell size GO:0045792 70 67 0,000 0,07459397 0,07989654 ! respiratory tube development GO:0030323 68 67 0,000 0,07459397 0,07987259 ! mRNA transport GO:0051028 70 67 0,000 0,07459397 0,07984864 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,07459397 0,07982471 ! tubulin binding GO:0015631 70 67 0,000 0,07459397 0,0798008 ! positive regulation of lymphocyte activation GO:0051251 72 67 0,000 0,07459397 0,0797769 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,07459397 0,07975302 ! regulation of caspase activity GO:0043281 70 67 0,000 0,07459397 0,07972915 ! Ras GTPase binding GO:0017016 70 67 0,000 0,07459397 0,07970529 ! humoral immune response GO:0006959 70 67 0,000 0,07459397 0,07968145 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,07459397 0,07965762 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,07459397 0,0796338 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,07459397 0,07961 ! nucleosome assembly GO:0006334 69 67 0,000 0,07459397 0,07958622 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,07459397 0,07956245 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,07566658 0,0806824 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,07566658 0,08065831 ! protein-DNA complex GO:0032993 69 68 0,000 0,07566658 0,08063424 ! learning or memory GO:0007611 72 68 0,000 0,07566658 0,08061019 ! chloride ion binding GO:0031404 70 68 0,000 0,07566658 0,08058615 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,07566658 0,08056212 ! chromatin assembly GO:0031497 70 68 0,000 0,07566658 0,08053811 ! calcium channel activity GO:0005262 73 68 0,000 0,07566658 0,08051411 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,07566658 0,08049012 ! respiratory system development GO:0060541 69 68 0,000 0,07566658 0,08046615 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,07566658 0,0804422 ! regulation of endopeptidase activity GO:0052548 72 69 0,000 0,07673801 0,08155698 ! eye development GO:0001654 74 69 0,000 0,07673801 0,08153271 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,07673801 0,08150846 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,07673801 0,08148422 ! axon guidance GO:0007411 74 69 0,000 0,07673801 0,08146 ! focal adhesion GO:0005925 75 69 0,000 0,07673801 0,08143579 ! regulation of DNA binding GO:0051101 72 70 0,000 0,07780828 0,08254705 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,07780828 0,08252253 ! early endosome GO:0005769 79 70 0,000 0,07780828 0,08249803 ! response to hypoxia GO:0001666 76 70 0,000 0,07780828 0,08247354 ! female pregnancy GO:0007565 71 70 0,000 0,07780828 0,08244907 ! rRNA processing GO:0006364 70 70 0,000 0,07780828 0,08242461 ! cytosolic ribosome GO:0022626 70 70 0,000 0,07780828 0,08240017 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,07887738 0,08350759 ! FAD binding GO:0050660 72 71 0,000 0,07887738 0,08348284 ! response to oxygen levels GO:0070482 77 71 0,000 0,07887738 0,08345811 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,07887738 0,08343339 ! defense response to bacterium GO:0042742 71 71 0,000 0,07887738 0,08340868 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,07887738 0,08338399 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,07887738 0,08335931 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,07887738 0,08333465 ! reproductive structure development GO:0048608 71 71 0,000 0,07887738 0,08331 ! neurotransmitter transport GO:0006836 73 71 0,000 0,07887738 0,08328537 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,07887738 0,08326075 ! phospholipase activity GO:0004620 75 71 0,000 0,07887738 0,08323614 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,07887738 0,08321155 ! cell projection part GO:0044463 75 71 0,000 0,07887738 0,08318698 ! amine biosynthetic process GO:0009309 75 72 0,000 0,07994531 0,08428837 ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,07994531 0,08426349 ! acute inflammatory response GO:0002526 76 72 0,000 0,07994531 0,08423862 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,07994531 0,08421378 ! lipid transporter activity GO:0005319 77 72 0,000 0,07994531 0,08418894 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,07994531 0,08416412 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,07994531 0,08413932 ! negative regulation of transport GO:0051051 74 73 0,000 0,08101208 0,08523692 ! vacuolar membrane GO:0005774 74 73 0,000 0,08101208 0,08521182 ! rRNA metabolic process GO:0016072 73 73 0,000 0,08101208 0,08518673 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,08101208 0,08516165 ! regulation of protein transport GO:0051223 77 73 0,000 0,08101208 0,08513659 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,08101208 0,08511154 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,08101208 0,08508651 ! hormone receptor binding GO:0051427 75 73 0,000 0,08101208 0,08506149 ! nucleosome organization GO:0034728 76 74 0,000 0,08207768 0,08615502 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,08207768 0,08612971 ! pore complex GO:0046930 78 74 0,000 0,08207768 0,0861044 ! regulation of peptidase activity GO:0052547 78 74 0,000 0,08207768 0,08607912 ! regulation of blood pressure GO:0008217 76 74 0,000 0,08207768 0,08605384 ! apical junction complex GO:0043296 74 74 0,000 0,08207768 0,08602858 ! cellular carbohydrate catabolic process GO:0044275 75 74 0,000 0,08207768 0,08600334 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,08207768 0,08597811 ! membrane raft GO:0045121 78 74 0,000 0,08207768 0,0859529 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,08207768 0,0859277 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,08207768 0,08590252 ! response to drug GO:0042493 77 75 0,000 0,08314212 0,08699106 ! small GTPase binding GO:0031267 78 75 0,000 0,08314212 0,08696558 ! cell-substrate junction GO:0030055 82 75 0,000 0,08314212 0,08694012 ! establishment of RNA localization GO:0051236 78 75 0,000 0,08314212 0,08691467 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! positive regulation of cell activation GO:0050867 80 75 0,000 0,08314212 0,08688923 GO:0002696|positive regulation of leukocyte activation, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,08314212 0,08686381 ! tube morphogenesis GO:0035239 79 75 0,000 0,08314212 0,0868384 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,08314212 0,08681301 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,08314212 0,08678763 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,08420539 0,08787185 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,08420539 0,08784618 ! regulation of ligase activity GO:0051340 78 76 0,000 0,08420539 0,08782052 ! vitamin metabolic process GO:0006766 77 76 0,000 0,08420539 0,08779488 ! inorganic anion transport GO:0015698 78 76 0,000 0,08420539 0,08776925 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,08420539 0,08774364 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,08420539 0,08771805 ! T cell activation GO:0042110 82 76 0,000 0,08420539 0,08769247 ! digestion GO:0007586 80 76 0,000 0,08420539 0,0876669 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,08420539 0,08764135 ! cilium GO:0005929 77 76 0,000 0,08420539 0,08761581 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,08526751 0,0886951 ! RNA localization GO:0006403 80 77 0,000 0,08526751 0,08866927 ! nuclear speck GO:0016607 80 77 0,000 0,08526751 0,08864346 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,08526751 0,08861766 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,08526751 0,08859188 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,08526751 0,08856611 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,08526751 0,08854036 ! vacuolar part GO:0044437 78 77 0,000 0,08526751 0,08851462 ! potassium channel complex GO:0034705 81 78 0,000 0,08632847 0,08958993 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,08632847 0,0895639 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,08632847 0,08953789 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,08738827 0,09061077 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,08738827 0,09058447 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,08738827 0,09055818 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,08738827 0,09053191 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,08738827 0,09050566 ! regulation of T cell activation GO:0050863 84 79 0,000 0,08738827 0,09047942 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,08738827 0,09045319 ! exocytosis GO:0006887 81 79 0,000 0,08738827 0,09042698 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,08738827 0,09040078 ! regulation of protein localization GO:0032880 83 79 0,000 0,08738827 0,0903746 ! alcohol catabolic process GO:0046164 83 80 0,000 0,08844691 0,09144294 ! GTPase binding GO:0051020 83 80 0,000 0,08844691 0,09141647 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,08844691 0,09139002 ! negative regulation of growth GO:0045926 84 80 0,000 0,08844691 0,09136359 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,08844691 0,09133716 ! regulation of lyase activity GO:0051339 83 80 0,000 0,08844691 0,09131076 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,08844691 0,09128437 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,08844691 0,09125799 ! monooxygenase activity GO:0004497 82 80 0,000 0,08844691 0,09123163 ! condensed chromosome GO:0000793 82 80 0,000 0,08844691 0,09120529 ! protein ubiquitination GO:0016567 86 80 0,000 0,08844691 0,09117896 ! ossification GO:0001503 85 81 0,000 0,0895044 0,09224248 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,0895044 0,09221587 ! sterol metabolic process GO:0016125 83 81 0,000 0,0895044 0,09218927 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,0895044 0,09216269 ! regulation of neurological system process GO:0031644 83 81 0,000 0,0895044 0,09213612 ! protein transporter activity GO:0008565 85 82 0,000 0,09056073 0,09319664 ! positive regulation of immune response GO:0050778 91 82 0,000 0,09056073 0,09316979 ! regulation of defense response GO:0031347 82 82 0,000 0,09056073 0,09314296 ! bone development GO:0060348 86 82 0,000 0,09056073 0,09311614 ! carboxylesterase activity GO:0004091 86 82 0,000 0,09056073 0,09308934 ! transcription initiation GO:0006352 86 82 0,000 0,09056073 0,09306255 ! mitochondrion organization GO:0007005 86 83 0,000 0,09161591 0,09411979 ! organelle outer membrane GO:0031968 87 83 0,000 0,09161591 0,09409272 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,09161591 0,09406567 ! heparin binding GO:0008201 90 83 0,000 0,09161591 0,09403863 ! amine transport GO:0015837 83 83 0,000 0,09161591 0,09401161 ! extracellular matrix part GO:0044420 85 83 0,000 0,09161591 0,0939846 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,09266993 0,09503858 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,09266993 0,09501129 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,09266993 0,09498402 ! regulation of membrane potential GO:0042391 92 84 0,000 0,09266993 0,09495676 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,09372281 0,09600807 ! cellular respiration GO:0045333 85 85 0,000 0,09372281 0,09598054 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,09372281 0,09595302 ! outer membrane GO:0019867 89 85 0,000 0,09372281 0,09592552 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,09372281 0,09589803 ! leukocyte differentiation GO:0002521 95 86 0,000 0,09477453 0,09694639 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,09477453 0,09691863 ! pigment granule GO:0048770 90 86 0,000 0,09477453 0,09689088 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,09477453 0,09686315 ! anion binding GO:0043168 89 86 0,000 0,09477453 0,09683544 ! sex differentiation GO:0007548 86 86 0,000 0,09477453 0,09680774 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,09477453 0,09678005 ! spindle GO:0005819 89 87 0,000 0,09582511 0,09782489 ! cell cycle arrest GO:0007050 92 87 0,000 0,09582511 0,09779693 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,09582511 0,09776899 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,09582511 0,09774106 ! protein processing GO:0016485 92 87 0,000 0,09582511 0,09771315 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,09687453 0,09875506 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,09687453 0,09872687 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,09687453 0,0986987 ! lipase activity GO:0016298 92 88 0,000 0,09687453 0,09867055 ! detection of stimulus GO:0051606 90 88 0,000 0,09687453 0,09864242 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,09792282 0,09968141 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,09792282 0,099653 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,09792282 0,09962461 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 0,000 0,09792282 0,09959623 ! regulation of binding GO:0051098 93 90 0,000 0,09896995 0,1006326 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,09896995 0,10060396 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! external side of plasma membrane GO:0009897 99 90 0,000 0,09896995 0,10057533 ! growth factor binding GO:0019838 92 90 0,000 0,09896995 0,10054671 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,09896995 0,10051812 ! adherens junction GO:0005912 96 90 0,000 0,09896995 0,10048954 ! ATP metabolic process GO:0046034 96 91 0,000 0,10001594 0,10152272 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,10001594 0,10149387 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,10001594 0,10146504 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,10001594 0,10143622 ! forebrain development GO:0030900 95 91 0,000 0,10001594 0,10140742 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,10001594 0,10137864 ! apical plasma membrane GO:0016324 96 91 0,000 0,10001594 0,10134987 ! angiogenesis GO:0001525 95 92 0,000 0,10106079 0,1023796 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,10106079 0,10235057 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,10106079 0,10232155 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,10106079 0,10229254 ! gland development GO:0048732 95 92 0,000 0,10106079 0,10226356 ! DNA packaging GO:0006323 94 92 0,000 0,10106079 0,10223459 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,1021045 0,10326116 ! receptor complex GO:0043235 97 93 0,000 0,1021045 0,10323193 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,1021045 0,10320271 ! hormone metabolic process GO:0042445 96 93 0,000 0,1021045 0,10317351 ! translational elongation GO:0006414 97 94 0,000 0,10314707 0,1041975 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,10314707 0,10416804 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,10314707 0,10413859 ! carbohydrate catabolic process GO:0016052 95 94 0,000 0,10314707 0,10410915 ! protein maturation GO:0051604 99 94 0,000 0,10314707 0,10407973 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,10314707 0,10405033 ! in utero embryonic development GO:0001701 97 95 0,000 0,1041885 0,1050712 ! regulation of lymphocyte activation GO:0051249 100 95 0,000 0,1041885 0,10504154 ! carboxylic acid binding GO:0031406 99 95 0,000 0,1041885 0,10501189 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,1041885 0,10498226 ! response to virus GO:0009615 102 95 0,000 0,1041885 0,10495264 ! peroxisome GO:0005777 97 96 0,000 0,10522878 0,10597067 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,10522878 0,10594079 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,10522878 0,10591093 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,10522878 0,10588109 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,10522878 0,10585127 ! cell fate commitment GO:0045165 98 96 0,000 0,10522878 0,10582146 ! response to nutrient levels GO:0031667 98 96 0,000 0,10522878 0,10579166 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,10626794 0,10680631 ! microtubule associated complex GO:0005875 104 97 0,000 0,10626794 0,10677625 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,10626794 0,10674622 ! anchoring junction GO:0070161 103 97 0,000 0,10626794 0,1067162 ! reproductive developmental process GO:0003006 97 97 0,000 0,10626794 0,1066862 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,10626794 0,10665621 ! unfolded protein binding GO:0051082 100 98 0,000 0,10730595 0,10766776 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 0,000 0,10730595 0,10763752 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,10730595 0,10760729 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,10730595 0,10757708 ! protein C-terminus binding GO:0008022 106 99 0,000 0,10834284 0,1085861 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,10834284 0,10855563 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,10834284 0,10852518 ! electron transport chain GO:0022900 102 100 0,000 0,10937858 0,10953195 ! tRNA metabolic process GO:0006399 101 100 0,000 0,10937858 0,10950124 ! protein polymerization GO:0051258 114 100 0,000 0,10937858 0,10947055 ! cytokine binding GO:0019955 101 100 0,000 0,10937858 0,10943988 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,10937858 0,10940922 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,10937858 0,10937858