pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5329-6-real-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 3,000 8,9E-08 2,047E-04 ! response to UV GO:0009411 75 46 3,000 9,495E-07 1,092E-03 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 2,000 2,265E-06 1,737E-03 ! phosphoinositide-mediated signaling GO:0048015 109 71 3,000 5,494E-06 3,159E-03 ! response to light stimulus GO:0009416 153 96 3,000 1,825E-05 8,396E-03 ! meiosis I GO:0007127 52 32 2,000 1,971E-05 7,555E-03 ! skeletal myofibril assembly GO:0014866 7 5 1,000 2,649E-05 8,703E-03 ! attachment of GPI anchor to protein GO:0016255 9 5 1,000 2,649E-05 7,615E-03 ! determination of adult lifespan GO:0008340 8 5 1,000 2,649E-05 6,769E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 3,969E-05 9,129E-03 ! negative regulation of DNA recombination GO:0045910 9 6 1,000 3,969E-05 8,299E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,551E-05 0,01063966 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 1,000 5,551E-05 9,821E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! multicellular organismal aging GO:0010259 11 7 1,000 5,551E-05 9,12E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,101E-05 0,01242193 ! UV protection GO:0009650 14 10 1,000 1,186E-04 0,01704671 ! meiosis GO:0007126 96 61 2,000 1,385E-04 0,01873217 GO:0051327|M phase of meiotic cell cycle, ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 1,448E-04 0,01850082 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! meiotic cell cycle GO:0051321 97 62 2,000 1,453E-04 0,01759296 ! immunoglobulin production during immune response GO:0002381 20 12 1,000 1,736E-04 0,01996033 ! protein import into nucleus GO:0006606 118 74 2,000 2,458E-04 0,0269204 ! nuclear import GO:0051170 121 75 2,000 2,558E-04 0,02673764 ! protein localization in nucleus GO:0034504 133 80 2,000 3,095E-04 0,03094534 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,143E-04 0,03011867 GO:0030968|endoplasmic reticulum unfolded protein response, ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 3,143E-04 0,02891392 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 1,000 3,143E-04 0,02780185 ! keratinization GO:0031424 17 17 1,000 3,558E-04 0,03031056 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 3,699E-04 0,03038865 ! peptide cross-linking GO:0018149 31 18 1,000 3,999E-04 0,03171505 ! somatic diversification of immunoglobulins GO:0016445 29 19 1,000 4,465E-04 0,03422946 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 5,472E-04 0,04059656 GO:0016444|somatic cell DNA recombination, ! regulation of DNA recombination GO:0000018 40 21 1,000 5,472E-04 0,03932792 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,472E-04 0,03813616 ! immunoglobulin production GO:0002377 33 21 1,000 5,472E-04 0,03701451 GO:0002440|production of molecular mediator of immune response, ! protein import GO:0017038 156 99 2,000 5,784E-04 0,03800925 ! protein localization in organelle GO:0033365 161 100 2,000 5,956E-04 0,03805395 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 6,579E-04 0,04089376 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 6,579E-04 0,03981761 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 6,579E-04 0,03879664 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 7,169E-04 0,04122311 ! fat cell differentiation GO:0045444 37 24 1,000 7,169E-04 0,04021766 ! base-excision repair GO:0006284 31 24 1,000 7,169E-04 0,0392601 ! GPI anchor biosynthetic process GO:0006506 37 27 1,000 9,089E-04 0,04861728 ! myofibril assembly GO:0030239 36 27 1,000 9,089E-04 0,04751234 GO:0055002|striated muscle cell development, ! GPI anchor metabolic process GO:0006505 40 28 1,000 9,778E-04 0,04997868 ! mismatch repair GO:0006298 34 29 1,000 1,049E-03 0,05245988 ! muscle cell development GO:0055001 38 29 1,000 1,049E-03 0,05134371 ! spindle organization GO:0007051 37 30 1,000 1,123E-03 0,05380971 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 1,199E-03 0,05628895 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 1,278E-03 0,05878028 ! phosphoinositide biosynthetic process GO:0046489 47 33 1,000 1,359E-03 0,06128264 ! actomyosin structure organization GO:0031032 43 33 1,000 1,359E-03 0,06010412 ! regulation of proteolysis GO:0030162 50 33 1,000 1,359E-03 0,05897008 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 1,442E-03 0,06143227 ! keratinocyte differentiation GO:0030216 47 35 1,000 1,528E-03 0,0639051 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,8E-03 0,07392821 ! response to calcium ion GO:0051592 58 40 1,000 1,993E-03 0,0804212 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 1,993E-03 0,07903463 ! double-strand break repair GO:0006302 67 40 1,000 1,993E-03 0,07769506 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,993E-03 0,07640014 ! JAK-STAT cascade GO:0007259 53 40 1,000 1,993E-03 0,07514768 ! protein amino acid lipidation GO:0006497 62 41 1,000 2,093E-03 0,07764742 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 2,196E-03 0,08015332 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 2,3E-03 0,08266484 ! response to insulin stimulus GO:0032868 63 43 1,000 2,3E-03 0,08139307 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,517E-03 0,08770264 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 2,517E-03 0,08639364 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 2,859E-03 0,09669063 ! regulation of DNA replication GO:0006275 75 48 1,000 2,859E-03 0,09528932 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 2,859E-03 0,09392804 GO:0019724|B cell mediated immunity, ! regulation of actin filament length GO:0030832 72 50 1,000 3,098E-03 0,10036232 ! skeletal muscle fiber development GO:0048741 73 50 1,000 3,098E-03 0,0989684 ! muscle fiber development GO:0048747 74 51 1,000 3,221E-03 0,10149267 ! regulation of protein catabolic process GO:0042176 77 51 1,000 3,221E-03 0,10012115 ! regulation of cellular component size GO:0032535 74 52 1,000 3,347E-03 0,10263231 ! aging GO:0007568 79 52 1,000 3,347E-03 0,10128188 ! nucleotide-excision repair GO:0006289 64 52 1,000 3,347E-03 0,09996653 ! glycerophospholipid biosynthetic process GO:0046474 75 53 1,000 3,474E-03 0,10244976 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 3,871E-03 0,11269736 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 4,008E-03 0,11521729 ! actin filament organization GO:0007015 95 59 1,000 4,288E-03 0,12174446 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 4,431E-03 0,12427919 ! glycerolipid biosynthetic process GO:0045017 85 60 1,000 4,431E-03 0,12278185 ! lipoprotein metabolic process GO:0042157 89 61 1,000 4,576E-03 0,1253042 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 4,576E-03 0,12383003 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 4,724E-03 0,12634026 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 4,724E-03 0,12488807 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 5,026E-03 0,13136098 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 5,026E-03 0,12988502 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,026E-03 0,12844185 ! adaptive immune response GO:0002250 94 64 1,000 5,026E-03 0,1270304 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 1,000 5,18E-03 0,12950574 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 5,18E-03 0,12811321 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 5,18E-03 0,1267503 ! regulation of actin filament-based process GO:0032970 99 66 1,000 5,337E-03 0,12920289 ! positive regulation of ligase activity GO:0051351 99 69 1,000 5,819E-03 0,13940894 ! response to metal ion GO:0010038 103 70 1,000 5,984E-03 0,14188433 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 5,984E-03 0,14043653 ! regulation of catabolic process GO:0009894 106 70 1,000 5,984E-03 0,13901798 ! muscle cell differentiation GO:0042692 104 71 1,000 6,151E-03 0,14147205 ! leukocyte mediated immunity GO:0002443 99 71 1,000 6,151E-03 0,14007134 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 6,151E-03 0,13869809 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 6,32E-03 0,14113123 GO:0045937|positive regulation of phosphate metabolic process, ! phospholipid biosynthetic process GO:0008654 102 74 1,000 6,665E-03 0,14740133 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 6,665E-03 0,14599751 ! blood coagulation GO:0007596 116 75 1,000 6,841E-03 0,14843033 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 1,000 6,841E-03 0,14704313 ! regulation of ligase activity GO:0051340 114 75 1,000 6,841E-03 0,14568162 ! response to unfolded protein GO:0006986 99 76 1,000 7,018E-03 0,14809463 ! positive regulation of protein modification process GO:0031401 107 78 1,000 7,38E-03 0,15431018 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 7,75E-03 0,16058581 GO:0010498|proteasomal protein catabolic process, ! hemostasis GO:0007599 125 81 1,000 7,938E-03 0,16301429 ! response to protein stimulus GO:0051789 111 81 1,000 7,938E-03 0,16157168 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 8,268E-03 0,1668048 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 8,268E-03 0,16535432 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 8,268E-03 0,16392885 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 8,268E-03 0,16252775 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 8,268E-03 0,1611504 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,268E-03 0,15979619 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 8,268E-03 0,15846456 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 8,268E-03 0,15715493 ! sleep GO:0030431 11 5 0,000 8,268E-03 0,15586678 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,268E-03 0,15459957 ! nucleotide-sugar transport GO:0015780 8 5 0,000 8,268E-03 0,1533528 ! regulation of interferon-beta production GO:0032648 5 5 0,000 8,268E-03 0,15212598 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 8,268E-03 0,15091863 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 8,268E-03 0,14973029 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 8,268E-03 0,14856052 ! tongue development GO:0043586 6 5 0,000 8,268E-03 0,14740889 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 8,268E-03 0,14627498 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,268E-03 0,14515837 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 8,268E-03 0,14405869 ! cobalt ion transport GO:0006824 9 5 0,000 8,268E-03 0,14297554 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 8,268E-03 0,14190856 ! SMAD protein complex assembly GO:0007183 9 5 0,000 8,268E-03 0,14085739 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 8,268E-03 0,13982167 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 8,268E-03 0,13880107 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 8,268E-03 0,13779527 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 8,268E-03 0,13680394 ! embryonic camera-type eye development GO:0031076 8 5 0,000 8,268E-03 0,13582676 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 8,268E-03 0,13486345 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 8,268E-03 0,13391371 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,268E-03 0,13297725 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,268E-03 0,1320538 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,268E-03 0,13114308 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 8,268E-03 0,13024484 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 8,268E-03 0,12935882 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,268E-03 0,12848478 ! malate metabolic process GO:0006108 7 5 0,000 8,268E-03 0,12762246 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 8,268E-03 0,12677165 ! behavioral response to pain GO:0048266 7 5 0,000 8,268E-03 0,1259321 ! clathrin coat assembly GO:0048268 11 5 0,000 8,268E-03 0,1251036 ! phototransduction, visible light GO:0007603 6 5 0,000 8,268E-03 0,12428593 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,268E-03 0,12347888 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 8,268E-03 0,12268224 ! mating behavior GO:0007617 6 5 0,000 8,268E-03 0,12189581 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,268E-03 0,12111941 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 8,268E-03 0,12035283 ! rhythmic behavior GO:0007622 12 5 0,000 8,268E-03 0,11959589 ! copulation GO:0007620 7 5 0,000 8,268E-03 0,11884842 ! glial cell fate commitment GO:0021781 12 5 0,000 8,268E-03 0,11811023 ! protein maturation by protein folding GO:0022417 12 5 0,000 8,268E-03 0,11738115 ! embryonic hemopoiesis GO:0035162 10 5 0,000 8,268E-03 0,11666102 ! regulation of potassium ion transport GO:0043266 9 5 0,000 8,268E-03 0,11594968 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 8,268E-03 0,11524695 ! apoptotic cell clearance GO:0043277 13 5 0,000 8,268E-03 0,11455269 ! lipoprotein particle clearance GO:0034381 9 5 0,000 8,268E-03 0,11386675 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 8,268E-03 0,11318897 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,268E-03 0,11251921 ! response to protozoan GO:0001562 9 5 0,000 8,268E-03 0,11185734 ! positive regulation of glycolysis GO:0045821 11 5 0,000 8,268E-03 0,1112032 ! lymph vessel development GO:0001945 7 5 0,000 8,268E-03 0,11055667 ! endochondral ossification GO:0001958 12 5 0,000 8,268E-03 0,10991761 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 8,268E-03 0,1092859 ! parathyroid gland development GO:0060017 8 5 0,000 8,268E-03 0,10866141 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 8,268E-03 0,10804402 ! anagen GO:0042640 6 5 0,000 8,268E-03 0,1074336 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 8,268E-03 0,10683004 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 8,268E-03 0,10623322 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 8,268E-03 0,10564304 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 8,268E-03 0,10505938 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 8,268E-03 0,10448213 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 8,268E-03 0,10391119 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 8,268E-03 0,10334645 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 8,268E-03 0,10278782 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 8,268E-03 0,1022352 ! cardiac muscle fiber development GO:0048739 7 5 0,000 8,268E-03 0,10168849 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 8,268E-03 0,10114759 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 8,268E-03 0,10061242 ! neutrophil mediated immunity GO:0002446 6 5 0,000 8,268E-03 0,10008288 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 8,268E-03 0,09955888 ! ovulation GO:0030728 6 5 0,000 8,268E-03 0,09904035 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 8,268E-03 0,09852719 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 8,268E-03 0,09801931 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 8,268E-03 0,09751665 ! response to pH GO:0009268 9 5 0,000 8,268E-03 0,09701912 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 8,268E-03 0,09652663 ! proline biosynthetic process GO:0006561 6 5 0,000 8,268E-03 0,09603913 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,268E-03 0,09555652 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 8,268E-03 0,09507873 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,268E-03 0,09460571 ! polyol catabolic process GO:0046174 7 5 0,000 8,268E-03 0,09413736 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,268E-03 0,09367363 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,268E-03 0,09321445 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,268E-03 0,09275974 ! sister chromatid cohesion GO:0007062 9 5 0,000 8,268E-03 0,09230945 ! nerve growth factor processing GO:0032455 7 5 0,000 8,268E-03 0,09186351 ! urea metabolic process GO:0019627 6 5 0,000 8,268E-03 0,09142186 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 8,268E-03 0,09098444 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,268E-03 0,09055118 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 8,268E-03 0,09012202 ! neutrophil activation GO:0042119 5 5 0,000 8,268E-03 0,08969692 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 8,268E-03 0,08927581 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 8,268E-03 0,08885863 ! response to food GO:0032094 5 5 0,000 8,268E-03 0,08844533 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 8,268E-03 0,08803587 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,268E-03 0,08763017 ! paraxial mesoderm development GO:0048339 9 5 0,000 8,268E-03 0,0872282 ! forebrain neuron development GO:0021884 7 5 0,000 8,268E-03 0,08682989 ! melanosome organization GO:0032438 7 5 0,000 8,268E-03 0,08643521 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 8,268E-03 0,0860441 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,268E-03 0,08565652 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 8,268E-03 0,08527241 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,268E-03 0,08489173 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 8,268E-03 0,08451443 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 8,268E-03 0,08414047 ! nucleoside transport GO:0015858 6 5 0,000 8,268E-03 0,08376981 ! nucleoside salvage GO:0043174 7 5 0,000 8,268E-03 0,0834024 GO:0006166|purine ribonucleoside salvage, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,268E-03 0,0830382 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 8,268E-03 0,08267716 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 8,268E-03 0,08231925 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,268E-03 0,08196443 ! early endosome to late endosome transport GO:0045022 11 5 0,000 8,268E-03 0,08161265 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,268E-03 0,08126388 ! depyrimidination GO:0045008 8 5 0,000 8,268E-03 0,08091807 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 8,268E-03 0,0805752 ! 5S class rRNA transcription GO:0042791 8 5 0,000 8,268E-03 0,08023522 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 8,268E-03 0,0798981 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,268E-03 0,07956379 ! neuronal ion channel clustering GO:0045161 7 5 0,000 8,268E-03 0,07923228 ! sodium ion homeostasis GO:0055078 6 5 0,000 8,268E-03 0,07890351 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 8,268E-03 0,07857747 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 8,268E-03 0,0782541 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 8,268E-03 0,07793339 ! monocyte differentiation GO:0030224 8 5 0,000 8,268E-03 0,07761529 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 8,268E-03 0,07729978 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 8,268E-03 0,07698683 ! centrosome duplication GO:0051298 5 5 0,000 8,268E-03 0,0766764 ! response to UV-C GO:0010225 6 5 0,000 8,268E-03 0,07636846 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 8,268E-03 0,07606299 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 8,268E-03 0,07575995 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 8,268E-03 0,07545931 ! regulation of dendrite development GO:0050773 12 5 0,000 8,268E-03 0,07516106 ! peptidyl-arginine modification GO:0018195 7 5 0,000 8,268E-03 0,07486515 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,268E-03 0,07457156 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 8,268E-03 0,07428026 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 8,268E-03 0,07399123 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 8,268E-03 0,07370445 ! regulation of dopamine secretion GO:0014059 12 5 0,000 8,268E-03 0,07341987 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 8,268E-03 0,07313749 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 8,268E-03 0,07285727 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 8,268E-03 0,07257919 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,268E-03 0,07230322 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 8,268E-03 0,07202934 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,268E-03 0,07175754 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 8,268E-03 0,07148777 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 8,268E-03 0,07122003 ! neural tube patterning GO:0021532 6 5 0,000 8,268E-03 0,07095428 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 8,268E-03 0,07069051 ! histone demethylation GO:0016577 9 5 0,000 8,268E-03 0,07042869 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,268E-03 0,07016881 ! regulation of sterol transport GO:0032371 7 5 0,000 8,268E-03 0,06991083 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 8,268E-03 0,06965475 ! enteric nervous system development GO:0048484 8 5 0,000 8,268E-03 0,06940054 ! establishment of planar polarity GO:0001736 6 5 0,000 8,268E-03 0,06914817 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 8,268E-03 0,06889763 ! muscle cell proliferation GO:0033002 8 5 0,000 8,268E-03 0,06864891 ! transcription termination GO:0006353 8 5 0,000 8,268E-03 0,06840197 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 8,268E-03 0,0681568 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 8,268E-03 0,06791338 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 8,268E-03 0,0676717 ! regulation of respiratory burst GO:0060263 8 5 0,000 8,268E-03 0,06743173 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 8,268E-03 0,06719345 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,268E-03 0,06695686 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,268E-03 0,06672192 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 8,268E-03 0,06648863 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 8,268E-03 0,06625696 ! apical protein localization GO:0045176 6 5 0,000 8,268E-03 0,0660269 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 8,268E-03 0,06579843 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 8,268E-03 0,06557154 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,268E-03 0,06534621 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 8,268E-03 0,06512242 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 8,268E-03 0,06490016 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 8,268E-03 0,06467941 ! triglyceride catabolic process GO:0019433 6 5 0,000 8,268E-03 0,06446016 ! glial cell migration GO:0008347 10 5 0,000 8,268E-03 0,06424239 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 8,268E-03 0,06402608 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,268E-03 0,06381123 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,268E-03 0,06359782 ! somatic stem cell maintenance GO:0035019 13 5 0,000 8,268E-03 0,06338582 ! cerebellar cortex formation GO:0021697 6 5 0,000 8,268E-03 0,06317524 ! neural plate development GO:0001840 6 5 0,000 8,268E-03 0,06296605 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 8,268E-03 0,06275824 ! regulation of sensory perception GO:0051931 6 5 0,000 8,268E-03 0,0625518 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 8,268E-03 0,06234671 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 8,268E-03 0,06214296 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 8,268E-03 0,06194054 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 8,268E-03 0,06173944 ! sensory cilium assembly GO:0035058 6 5 0,000 8,268E-03 0,06153963 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 8,268E-03 0,06134112 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,268E-03 0,06114388 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 8,268E-03 0,06094791 ! spindle assembly GO:0051225 5 5 0,000 8,268E-03 0,06075319 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 8,268E-03 0,0605597 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 8,268E-03 0,06036745 ! protein amino acid prenylation GO:0018346 9 5 0,000 8,268E-03 0,06017641 ! organ regeneration GO:0031100 7 5 0,000 8,268E-03 0,05998658 ! NAD biosynthetic process GO:0009435 7 5 0,000 8,268E-03 0,05979795 ! carnitine metabolic process GO:0009437 5 5 0,000 8,268E-03 0,05961049 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 8,268E-03 0,05942421 ! cellular anion homeostasis GO:0030002 6 5 0,000 8,268E-03 0,05923909 GO:0055081|anion homeostasis, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 8,515E-03 0,06081872 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 8,909E-03 0,06343987 ! skeletal muscle tissue development GO:0007519 123 87 1,000 9,109E-03 0,06466599 GO:0060538|skeletal muscle organ development, ! interphase GO:0051325 159 88 1,000 9,312E-03 0,06589884 ! tRNA transcription GO:0009304 11 6 0,000 9,913E-03 0,06994061 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 9,913E-03 0,06972672 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 9,913E-03 0,06951414 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 9,913E-03 0,06930285 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,913E-03 0,06909284 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 9,913E-03 0,0688841 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 9,913E-03 0,06867662 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 9,913E-03 0,06847038 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 9,913E-03 0,06826538 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 9,913E-03 0,06806161 ! positive regulation of axon extension GO:0045773 8 6 0,000 9,913E-03 0,06785904 ! prostate gland development GO:0030850 9 6 0,000 9,913E-03 0,06765768 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 9,913E-03 0,06745751 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 9,913E-03 0,06725852 ! forebrain neuron differentiation GO:0021879 9 6 0,000 9,913E-03 0,0670607 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 9,913E-03 0,06686404 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 9,913E-03 0,06666853 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 9,913E-03 0,06647416 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 9,913E-03 0,06628092 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 9,913E-03 0,06608881 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 9,913E-03 0,0658978 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 9,913E-03 0,06570789 ! neuron adhesion GO:0007158 9 6 0,000 9,913E-03 0,06551908 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 9,913E-03 0,06533134 ! establishment of tissue polarity GO:0007164 7 6 0,000 9,913E-03 0,06514468 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 9,913E-03 0,06495908 ! signal peptide processing GO:0006465 8 6 0,000 9,913E-03 0,06477454 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 9,913E-03 0,06459104 ! mRNA stabilization GO:0048255 15 6 0,000 9,913E-03 0,06440858 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 9,913E-03 0,06422715 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 9,913E-03 0,06404674 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 9,913E-03 0,06386733 ! opsonization GO:0008228 8 6 0,000 9,913E-03 0,06368893 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 9,913E-03 0,06351153 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 9,913E-03 0,06333511 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 9,913E-03 0,06315966 ! protein amino acid dealkylation GO:0008214 11 6 0,000 9,913E-03 0,06298519 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 9,913E-03 0,06281168 ! photoreceptor cell development GO:0042461 10 6 0,000 9,913E-03 0,06263912 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 9,913E-03 0,0624675 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 9,913E-03 0,06229683 ! mechanosensory behavior GO:0007638 8 6 0,000 9,913E-03 0,06212708 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 9,913E-03 0,06195826 ! negative regulation of endocytosis GO:0045806 8 6 0,000 9,913E-03 0,06179035 ! response to interferon-gamma GO:0034341 12 6 0,000 9,913E-03 0,06162335 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 9,913E-03 0,06145725 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 9,913E-03 0,06129204 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,913E-03 0,06112772 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 9,913E-03 0,06096427 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 9,913E-03 0,0608017 ! cGMP-mediated signaling GO:0019934 10 6 0,000 9,913E-03 0,06064 ! activation of MAPKKK activity GO:0000185 10 6 0,000 9,913E-03 0,06047915 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 9,913E-03 0,06031915 ! thymic T cell selection GO:0045061 12 6 0,000 9,913E-03 0,06016 ! protein lipoylation GO:0009249 10 6 0,000 9,913E-03 0,06000168 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 9,913E-03 0,05984419 ! pigment granule organization GO:0048753 11 6 0,000 9,913E-03 0,05968753 ! drug transport GO:0015893 6 6 0,000 9,913E-03 0,05953169 ! cysteine metabolic process GO:0006534 7 6 0,000 9,913E-03 0,05937666 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 9,913E-03 0,05922244 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 9,913E-03 0,05906901 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,913E-03 0,05891638 ! histidine metabolic process GO:0006547 6 6 0,000 9,913E-03 0,05876453 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 9,913E-03 0,05861347 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 9,913E-03 0,05846317 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 9,913E-03 0,05831365 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 9,913E-03 0,05816489 ! adenohypophysis development GO:0021984 10 6 0,000 9,913E-03 0,05801689 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 9,913E-03 0,05786964 ! hyperosmotic response GO:0006972 8 6 0,000 9,913E-03 0,05772313 ! microtubule nucleation GO:0007020 10 6 0,000 9,913E-03 0,05757737 ! ER overload response GO:0006983 7 6 0,000 9,913E-03 0,05743234 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 9,913E-03 0,05728804 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 9,913E-03 0,05714446 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 9,913E-03 0,0570016 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 9,913E-03 0,05685945 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 9,913E-03 0,05671801 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 9,913E-03 0,05657727 ! response to dietary excess GO:0002021 7 6 0,000 9,913E-03 0,05643722 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 9,913E-03 0,05629787 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 9,913E-03 0,05615921 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 9,913E-03 0,05602122 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 9,913E-03 0,05588392 ! glycerol ether catabolic process GO:0044269 8 6 0,000 9,913E-03 0,05574728 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 9,913E-03 0,05561131 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,913E-03 0,05547601 ! neuron apoptosis GO:0051402 8 6 0,000 9,913E-03 0,05534135 ! organic alcohol transport GO:0015850 9 6 0,000 9,913E-03 0,05520736 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 9,913E-03 0,05507401 ! T cell mediated immunity GO:0002456 12 6 0,000 9,913E-03 0,0549413 ! male sex determination GO:0030238 9 6 0,000 9,913E-03 0,05480923 ! carnitine transport GO:0015879 8 6 0,000 9,913E-03 0,05467779 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 9,913E-03 0,05454698 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 9,913E-03 0,0544168 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,913E-03 0,05428723 ! positive regulation of exocytosis GO:0045921 6 6 0,000 9,913E-03 0,05415829 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 9,913E-03 0,05402995 ! parturition GO:0007567 12 6 0,000 9,913E-03 0,05390222 ! negative regulation of translational initiation GO:0045947 7 6 0,000 9,913E-03 0,05377509 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 9,913E-03 0,05364856 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 9,913E-03 0,05352262 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 9,913E-03 0,05339728 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 9,913E-03 0,05327252 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 9,913E-03 0,05314834 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 9,913E-03 0,05302474 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 9,913E-03 0,05290171 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 9,913E-03 0,05277926 ! macrophage differentiation GO:0030225 10 6 0,000 9,913E-03 0,05265736 ! astrocyte development GO:0014002 14 6 0,000 9,913E-03 0,05253603 ! hyaluronan metabolic process GO:0030212 6 6 0,000 9,913E-03 0,05241526 ! purine base biosynthetic process GO:0009113 14 6 0,000 9,913E-03 0,05229504 ! interaction with symbiont GO:0051702 8 6 0,000 9,913E-03 0,05217537 ! anterograde axon cargo transport GO:0008089 8 6 0,000 9,913E-03 0,05205625 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,913E-03 0,05193767 ! eating behavior GO:0042755 6 6 0,000 9,913E-03 0,05181963 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 9,913E-03 0,05170213 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 9,913E-03 0,05158515 ! response to copper ion GO:0046688 9 6 0,000 9,913E-03 0,05146871 ! DNA topological change GO:0006265 8 6 0,000 9,913E-03 0,05135279 ! response to exogenous dsRNA GO:0043330 8 6 0,000 9,913E-03 0,05123739 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 9,913E-03 0,05112251 ! establishment of melanosome localization GO:0032401 9 6 0,000 9,913E-03 0,05100814 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,913E-03 0,05089428 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,913E-03 0,05078093 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 9,913E-03 0,05066808 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 9,913E-03 0,05055574 ! nucleoside catabolic process GO:0009164 6 6 0,000 9,913E-03 0,05044389 ! gas homeostasis GO:0033483 11 6 0,000 9,913E-03 0,05033253 ! hair follicle maturation GO:0048820 7 6 0,000 9,913E-03 0,05022167 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 9,913E-03 0,05011129 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 9,913E-03 0,0500014 ! Schwann cell development GO:0014044 14 6 0,000 9,913E-03 0,04989199 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 9,913E-03 0,04978305 ! dendrite morphogenesis GO:0048813 9 6 0,000 9,913E-03 0,04967459 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,913E-03 0,0495666 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 9,913E-03 0,04945909 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 9,913E-03 0,04935203 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 9,913E-03 0,04924544 ! histone ubiquitination GO:0016574 7 6 0,000 9,913E-03 0,04913931 ! regulation of meiosis GO:0040020 10 6 0,000 9,913E-03 0,04903363 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 9,913E-03 0,04892841 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 9,913E-03 0,04882364 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 9,913E-03 0,04871931 ! regulation of mast cell activation GO:0033003 6 6 0,000 9,913E-03 0,04861543 ! membrane to membrane docking GO:0022614 12 6 0,000 9,913E-03 0,048512 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 9,913E-03 0,048409 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 9,913E-03 0,04830644 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 9,913E-03 0,04820431 ! receptor internalization GO:0031623 9 6 0,000 9,913E-03 0,04810261 ! neutrophil homeostasis GO:0001780 6 6 0,000 9,913E-03 0,04800134 ! coenzyme A metabolic process GO:0015936 9 6 0,000 9,913E-03 0,0479005 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,913E-03 0,04780008 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 9,913E-03 0,04770008 ! protein deubiquitination GO:0016579 8 6 0,000 9,913E-03 0,0476005 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 9,913E-03 0,04750133 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 9,913E-03 0,04740257 ! peptidyl-histidine modification GO:0018202 9 6 0,000 9,913E-03 0,04730423 ! axonal fasciculation GO:0007413 9 6 0,000 9,913E-03 0,04720629 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 9,913E-03 0,04710876 ! thiamin metabolic process GO:0006772 6 6 0,000 9,913E-03 0,04701163 ! midbrain development GO:0030901 6 6 0,000 9,913E-03 0,04691489 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 9,913E-03 0,04681856 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,913E-03 0,04672262 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 9,913E-03 0,04662707 ! progesterone metabolic process GO:0042448 8 6 0,000 9,913E-03 0,04653191 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 9,913E-03 0,04643714 ! glycolipid catabolic process GO:0019377 13 6 0,000 9,913E-03 0,04634276 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 9,913E-03 0,04624876 ! positive regulation of glucose import GO:0046326 6 6 0,000 9,913E-03 0,04615514 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 9,913E-03 0,0460619 ! adult feeding behavior GO:0008343 6 6 0,000 9,913E-03 0,04596903 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 9,913E-03 0,04587654 ! blastocyst growth GO:0001832 15 6 0,000 9,913E-03 0,04578441 ! pigment granule transport GO:0051904 12 6 0,000 9,913E-03 0,04569266 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 9,913E-03 0,04560128 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 9,913E-03 0,04551026 ! catecholamine transport GO:0051937 7 6 0,000 9,913E-03 0,0454196 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,913E-03 0,0453293 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 9,913E-03 0,04523936 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 9,913E-03 0,04514978 ! negative regulation of B cell activation GO:0050869 9 6 0,000 9,913E-03 0,04506055 ! protein prenylation GO:0018342 10 6 0,000 9,913E-03 0,04497167 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,913E-03 0,04488315 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 9,913E-03 0,04479497 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 9,913E-03 0,04470713 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 9,913E-03 0,04461964 ! positive regulation of coagulation GO:0050820 11 6 0,000 9,913E-03 0,0445325 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,01014109 0,04546687 ! DNA recombination GO:0006310 146 92 1,000 0,01014109 0,04537841 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01035338 0,04623841 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01155629 0,05151059 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01155629 0,05141096 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01155629 0,05131171 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01155629 0,05121284 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01155629 0,05111436 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01155629 0,05101625 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01155629 0,05091852 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01155629 0,05082116 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01155629 0,05072417 ! reproductive behavior GO:0019098 12 7 0,000 0,01155629 0,05062755 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01155629 0,0505313 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01155629 0,05043542 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01155629 0,0503399 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01155629 0,05024474 ! oligopeptide transport GO:0006857 11 7 0,000 0,01155629 0,05014993 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01155629 0,05005549 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01155629 0,0499614 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01155629 0,04986766 ! RNA methylation GO:0001510 11 7 0,000 0,01155629 0,04977428 ! pericardium development GO:0060039 8 7 0,000 0,01155629 0,04968124 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01155629 0,04958855 ! fibril organization GO:0043206 13 7 0,000 0,01155629 0,04949621 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01155629 0,04940421 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01155629 0,04931255 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01155629 0,04922123 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01155629 0,04913025 ! lipoprotein transport GO:0042953 9 7 0,000 0,01155629 0,0490396 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01155629 0,04894929 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01155629 0,04885931 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01155629 0,04876966 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01155629 0,04868034 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01155629 0,04859134 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01155629 0,04850267 ! chemosensory behavior GO:0007635 9 7 0,000 0,01155629 0,04841433 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01155629 0,0483263 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01155629 0,04823859 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01155629 0,04815121 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01155629 0,04806413 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01155629 0,04797737 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01155629 0,04789093 ! reflex GO:0060004 12 7 0,000 0,01155629 0,04780479 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01155629 0,04771897 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01155629 0,04763345 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01155629 0,04754824 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01155629 0,04746333 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01155629 0,04737873 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01155629 0,04729442 ! spinal cord patterning GO:0021511 7 7 0,000 0,01155629 0,04721042 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01155629 0,04712671 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01155629 0,0470433 ! adrenal gland development GO:0030325 17 7 0,000 0,01155629 0,04696019 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01155629 0,04687736 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01155629 0,04679483 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01155629 0,04671259 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01155629 0,04663064 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01155629 0,04654898 ! endosome organization GO:0007032 10 7 0,000 0,01155629 0,0464676 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01155629 0,0463865 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01155629 0,04630569 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01155629 0,04622516 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01155629 0,0461449 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01155629 0,04606493 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01155629 0,04598523 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01155629 0,04590581 ! galactose metabolic process GO:0006012 10 7 0,000 0,01155629 0,04582666 ! vesicle fusion GO:0006906 15 7 0,000 0,01155629 0,04574779 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01155629 0,04566918 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01155629 0,04559085 ! organ growth GO:0035265 11 7 0,000 0,01155629 0,04551278 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01155629 0,04543498 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01155629 0,04535745 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01155629 0,04528018 ! retinol metabolic process GO:0042572 9 7 0,000 0,01155629 0,04520317 ! behavioral fear response GO:0001662 13 7 0,000 0,01155629 0,04512643 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01155629 0,04504994 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01155629 0,04497371 ! rRNA modification GO:0000154 12 7 0,000 0,01155629 0,04489775 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01155629 0,04482203 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01155629 0,04474657 ! response to UV-B GO:0010224 11 7 0,000 0,01155629 0,04467137 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01155629 0,04459642 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01155629 0,04452172 ! intermediate filament organization GO:0045109 11 7 0,000 0,01155629 0,04444727 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01155629 0,04437306 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01155629 0,04429911 ! fibrinolysis GO:0042730 9 7 0,000 0,01155629 0,0442254 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01155629 0,04415194 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01155629 0,04407872 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01155629 0,04400574 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01155629 0,043933 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01155629 0,0438605 ! response to tropane GO:0014073 13 7 0,000 0,01155629 0,04378825 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01155629 0,04371623 ! melanosome localization GO:0032400 10 7 0,000 0,01155629 0,04364444 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01155629 0,04357289 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01155629 0,04350158 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01155629 0,0434305 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01155629 0,04335965 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01155629 0,04328903 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01155629 0,04321864 ! mast cell activation GO:0045576 9 7 0,000 0,01155629 0,04314848 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01155629 0,04307855 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01155629 0,04300884 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01155629 0,04293936 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01155629 0,04287011 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01155629 0,04280107 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01155629 0,04273226 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01155629 0,04266367 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01155629 0,0425953 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01155629 0,04252714 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01155629 0,04245921 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01155629 0,04239149 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01155629 0,04232399 ! response to tumor cell GO:0002347 12 7 0,000 0,01155629 0,0422567 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01155629 0,04218963 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01155629 0,04212277 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01155629 0,04205612 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01155629 0,04198968 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01155629 0,04192345 ! diuresis GO:0030146 12 7 0,000 0,01155629 0,04185743 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01155629 0,04179161 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01155629 0,04172601 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01155629 0,0416606 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01155629 0,04159541 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01155629 0,04153041 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01155629 0,04146562 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01155629 0,04140104 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01155629 0,04133665 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01155629 0,04127246 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01155629 0,04120847 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01155629 0,04114468 ! lymph node development GO:0048535 9 7 0,000 0,01155629 0,04108109 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01155629 0,04101769 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01155629 0,04095449 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01155629 0,04089148 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01155629 0,04082867 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01155629 0,04076605 ! ATP catabolic process GO:0006200 10 7 0,000 0,01155629 0,04070362 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01155629 0,04064138 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01155629 0,04057934 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01155629 0,04051748 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01155629 0,04045581 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01155629 0,04039432 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01155629 0,04033303 ! muscle adaptation GO:0043500 12 7 0,000 0,01155629 0,04027192 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01155629 0,04021099 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01155629 0,04015025 ! retina homeostasis GO:0001895 9 7 0,000 0,01155629 0,04008969 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01155629 0,04002932 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01155629 0,03996912 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01155629 0,03990911 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01155629 0,03984927 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01155629 0,03978962 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01155629 0,03973014 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01155629 0,03967084 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01189435 0,04077048 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,01189435 0,04070981 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,01189435 0,04064932 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01319663 0,04503299 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01319663 0,04496628 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01319663 0,04489976 ! axon extension GO:0048675 11 8 0,000 0,01319663 0,04483344 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01319663 0,04476731 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01319663 0,04470138 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01319663 0,04463564 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01319663 0,0445701 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01319663 0,04450475 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01319663 0,04443959 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01319663 0,04437462 ! phosphate transport GO:0006817 10 8 0,000 0,01319663 0,04430984 ! N-glycan processing GO:0006491 12 8 0,000 0,01319663 0,04424524 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01319663 0,04418084 ! UTP metabolic process GO:0046051 8 8 0,000 0,01319663 0,04411662 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01319663 0,04405259 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01319663 0,04398875 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01319663 0,04392509 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01319663 0,04386161 ! succinate metabolic process GO:0006105 14 8 0,000 0,01319663 0,04379832 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01319663 0,04373521 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01319663 0,04367228 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01319663 0,04360954 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01319663 0,04354697 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01319663 0,04348458 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01319663 0,04342237 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01319663 0,04336034 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01319663 0,04329848 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01319663 0,04323681 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01319663 0,0431753 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01319663 0,04311397 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01319663 0,04305282 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01319663 0,04299184 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01319663 0,04293103 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01319663 0,04287039 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01319663 0,04280993 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01319663 0,04274963 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01319663 0,0426895 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01319663 0,04262955 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01319663 0,04256976 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01319663 0,04251014 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01319663 0,04245068 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01319663 0,04239139 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01319663 0,04233227 ! melanin metabolic process GO:0006582 12 8 0,000 0,01319663 0,04227331 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01319663 0,04221452 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01319663 0,04215589 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01319663 0,04209742 ! macrophage activation GO:0042116 12 8 0,000 0,01319663 0,04203911 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01319663 0,04198096 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01319663 0,04192298 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01319663 0,04186516 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01319663 0,04180749 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01319663 0,04174998 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01319663 0,04169263 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01319663 0,04163544 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01319663 0,04157841 ! ruffle organization GO:0031529 11 8 0,000 0,01319663 0,04152153 ! osteoblast development GO:0002076 13 8 0,000 0,01319663 0,04146481 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01319663 0,04140824 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01319663 0,04135182 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01319663 0,04129556 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01319663 0,04123945 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01319663 0,0411835 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01319663 0,04112769 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01319663 0,04107204 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01319663 0,04101654 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01319663 0,04096118 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01319663 0,04090598 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01319663 0,04085093 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01319663 0,04079602 ! segment specification GO:0007379 10 8 0,000 0,01319663 0,04074126 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01319663 0,04068665 ! cellular extravasation GO:0045123 11 8 0,000 0,01319663 0,04063218 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01319663 0,04057786 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01319663 0,04052368 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01319663 0,04046965 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01319663 0,04041576 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01319663 0,04036202 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01319663 0,04030842 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01319663 0,04025496 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01319663 0,04020164 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01319663 0,04014846 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01319663 0,04009543 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01319663 0,04004253 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01319663 0,03998977 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01319663 0,03993715 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01319663 0,03988467 ! icosanoid secretion GO:0032309 12 8 0,000 0,01319663 0,03983233 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01319663 0,03978013 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01319663 0,03972806 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01319663 0,03967613 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01319663 0,03962433 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01319663 0,03957267 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01319663 0,03952114 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01319663 0,03946975 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01319663 0,03941849 ! sterol catabolic process GO:0016127 9 8 0,000 0,01319663 0,03936736 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01319663 0,03931637 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01319663 0,03926551 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01319663 0,03921478 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01319663 0,03916418 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01319663 0,03911371 ! prophase GO:0051324 11 8 0,000 0,01319663 0,03906337 ! S phase GO:0051320 8 8 0,000 0,01319663 0,03901316 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01319663 0,03896308 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01319663 0,03891313 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01319663 0,0388633 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01319663 0,0388136 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01319663 0,03876403 ! hormone catabolic process GO:0042447 13 8 0,000 0,01319663 0,03871459 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01319663 0,03866527 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01319663 0,03861608 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01319663 0,03856701 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01319663 0,03851807 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01319663 0,03846925 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01319663 0,03842055 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01319663 0,03837198 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01319663 0,03832353 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01319663 0,0382752 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01319663 0,038227 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01319663 0,03817892 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01319663 0,03813095 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01319663 0,03808311 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01319663 0,03803539 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01319663 0,03798778 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01319663 0,0379403 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01483433 0,04259546 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01483433 0,04254235 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01483433 0,04248937 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01483433 0,04243652 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01483433 0,04238381 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01483433 0,04233122 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01483433 0,04227877 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01483433 0,04222644 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01483433 0,04217425 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01483433 0,04212218 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01483433 0,04207024 ! GTP metabolic process GO:0046039 9 9 0,000 0,01483433 0,04201843 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01483433 0,04196675 ! social behavior GO:0035176 14 9 0,000 0,01483433 0,04191519 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01483433 0,04186376 ! artery development GO:0060840 19 9 0,000 0,01483433 0,04181246 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01483433 0,04176128 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01483433 0,04171023 ! response to pain GO:0048265 16 9 0,000 0,01483433 0,0416593 ! protein complex disassembly GO:0043241 17 9 0,000 0,01483433 0,04160849 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01483433 0,04155781 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01483433 0,04150726 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01483433 0,04145682 ! lung alveolus development GO:0048286 17 9 0,000 0,01483433 0,04140651 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01483433 0,04135632 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01483433 0,04130625 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01483433 0,04125631 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01483433 0,04120648 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01483433 0,04115677 ! protein targeting to ER GO:0045047 19 9 0,000 0,01483433 0,04110719 ! T cell selection GO:0045058 18 9 0,000 0,01483433 0,04105772 ! endoderm development GO:0007492 12 9 0,000 0,01483433 0,04100837 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01483433 0,04095914 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01483433 0,04091003 ! arginine catabolic process GO:0006527 10 9 0,000 0,01483433 0,04086104 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01483433 0,04081216 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01483433 0,0407634 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01483433 0,04071475 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01483433 0,04066623 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01483433 0,04061781 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01483433 0,04056952 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01483433 0,04052134 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01483433 0,04047327 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01483433 0,04042531 ! mannose metabolic process GO:0006013 9 9 0,000 0,01483433 0,04037747 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01483433 0,04032975 ! receptor clustering GO:0043113 15 9 0,000 0,01483433 0,04028213 ! epithelial cell development GO:0002064 10 9 0,000 0,01483433 0,04023463 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01483433 0,04018724 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01483433 0,04013996 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01483433 0,04009279 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01483433 0,04004573 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01483433 0,03999879 ! motor axon guidance GO:0008045 14 9 0,000 0,01483433 0,03995195 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01483433 0,03990522 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01483433 0,0398586 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01483433 0,03981209 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01483433 0,03976569 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01483433 0,0397194 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01483433 0,03967321 ! DNA ligation GO:0006266 14 9 0,000 0,01483433 0,03962714 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01483433 0,03958117 ! response to amine stimulus GO:0014075 13 9 0,000 0,01483433 0,0395353 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01483433 0,03948954 ! erythrocyte development GO:0048821 11 9 0,000 0,01483433 0,03944389 ! renal water homeostasis GO:0003091 14 9 0,000 0,01483433 0,03939834 ! postreplication repair GO:0006301 11 9 0,000 0,01483433 0,0393529 ! mRNA cleavage GO:0006379 13 9 0,000 0,01483433 0,03930756 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01483433 0,03926233 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01483433 0,0392172 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01483433 0,03917217 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01483433 0,03912725 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01483433 0,03908243 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01483433 0,03903772 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01483433 0,0389931 ! acid secretion GO:0046717 14 9 0,000 0,01483433 0,03894859 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01483433 0,03890418 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01483433 0,03885987 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01483433 0,03881566 ! purine base metabolic process GO:0006144 18 9 0,000 0,01483433 0,03877155 ! oocyte differentiation GO:0009994 12 9 0,000 0,01483433 0,03872754 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01483433 0,03868363 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01483433 0,03863982 ! spleen development GO:0048536 15 9 0,000 0,01483433 0,03859611 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01483433 0,0385525 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01483433 0,03850899 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01483433 0,03846557 ! detection of calcium ion GO:0005513 13 9 0,000 0,01483433 0,03842226 ! blastocyst formation GO:0001825 12 9 0,000 0,01483433 0,03837904 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01483433 0,03833592 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01483433 0,03829289 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01483433 0,03824996 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01483433 0,03820713 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01483433 0,03816439 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01483433 0,03812175 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01483433 0,0380792 ! prepulse inhibition GO:0060134 14 9 0,000 0,01483433 0,03803675 ! embryonic placenta development GO:0001892 12 9 0,000 0,01483433 0,03799439 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01483433 0,03795213 ! insulin secretion GO:0030073 17 9 0,000 0,01483433 0,03790996 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01483433 0,03786788 ! response to nicotine GO:0035094 16 9 0,000 0,01483433 0,0378259 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01483433 0,03778401 ! nucleus localization GO:0051647 15 9 0,000 0,01483433 0,03774222 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01483433 0,03770051 ! localization within membrane GO:0051668 15 9 0,000 0,01483433 0,0376589 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01646942 0,04176368 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01646942 0,04171768 ! neuron fate specification GO:0048665 11 10 0,000 0,01646942 0,04167179 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01646942 0,04162599 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01646942 0,0415803 ! thyroid gland development GO:0030878 19 10 0,000 0,01646942 0,04153471 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01646942 0,04148922 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01646942 0,04144382 ! synapsis GO:0007129 13 10 0,000 0,01646942 0,04139853 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01646942 0,04135334 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01646942 0,04130824 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01646942 0,04126324 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01646942 0,04121834 ! sulfate transport GO:0008272 12 10 0,000 0,01646942 0,04117354 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01646942 0,04112883 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01646942 0,04108422 ! androgen metabolic process GO:0008209 13 10 0,000 0,01646942 0,04103971 ! phospholipid efflux GO:0033700 16 10 0,000 0,01646942 0,0409953 ! hippocampus development GO:0021766 19 10 0,000 0,01646942 0,04095098 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01646942 0,04090676 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01646942 0,04086263 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01646942 0,04081859 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01646942 0,04077466 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01646942 0,04073081 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01646942 0,04068706 ! pathogenesis GO:0009405 13 10 0,000 0,01646942 0,04064341 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01646942 0,04059984 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01646942 0,04055638 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01646942 0,040513 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01646942 0,04046972 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01646942 0,04042653 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01646942 0,04038343 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01646942 0,04034042 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01646942 0,04029751 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01646942 0,04025468 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01646942 0,04021195 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01646942 0,04016931 ! response to X-ray GO:0010165 16 10 0,000 0,01646942 0,04012675 ! B cell proliferation GO:0042100 14 10 0,000 0,01646942 0,04008429 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01646942 0,04004192 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01646942 0,03999964 ! forebrain cell migration GO:0021885 17 10 0,000 0,01646942 0,03995744 ! lipid digestion GO:0044241 15 10 0,000 0,01646942 0,03991534 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01646942 0,03987332 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01646942 0,03983139 ! entry into host cell GO:0030260 20 10 0,000 0,01646942 0,03978955 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01646942 0,0397478 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01646942 0,03970614 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01646942 0,03966456 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01646942 0,03962307 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01646942 0,03958167 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01646942 0,03954035 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01646942 0,03949912 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01646942 0,03945797 ! regulation of organ growth GO:0046620 11 10 0,000 0,01646942 0,03941691 ! response to dsRNA GO:0043331 18 10 0,000 0,01646942 0,03937594 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01646942 0,03933505 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01646942 0,03929425 ! embryonic axis specification GO:0000578 12 10 0,000 0,01646942 0,03925353 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01646942 0,03921289 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01646942 0,03917234 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01646942 0,03913188 ! cranial nerve development GO:0021545 12 10 0,000 0,01646942 0,03909149 ! fucose catabolic process GO:0019317 16 10 0,000 0,01646942 0,03905119 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01646942 0,03901097 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01646942 0,03897084 ! protein sumoylation GO:0016925 12 10 0,000 0,01646942 0,03893079 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01646942 0,03889082 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01646942 0,03885093 ! zymogen activation GO:0031638 14 10 0,000 0,01646942 0,03881112 ! salivary gland development GO:0007431 22 10 0,000 0,01646942 0,0387714 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01646942 0,03873175 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01646942 0,03869219 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01646942 0,03865271 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01646942 0,03861331 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01646942 0,03857399 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01646942 0,03853475 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01646942 0,03849558 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01646942 0,0384565 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01646942 0,0384175 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01646942 0,03837858 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01646942 0,03833973 ! detection of bacterium GO:0016045 10 10 0,000 0,01646942 0,03830097 ! embryonic gut development GO:0048566 11 10 0,000 0,01646942 0,03826228 ! activation of innate immune response GO:0002218 10 10 0,000 0,01646942 0,03822367 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01646942 0,03818514 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01646942 0,03814668 ! developmental induction GO:0031128 13 10 0,000 0,01646942 0,0381083 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01646942 0,03807001 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01646942 0,03803178 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01646942 0,03799364 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01646942 0,03795557 ! rRNA transcription GO:0009303 17 11 0,000 0,01810188 0,041676 ! respiratory burst GO:0045730 14 11 0,000 0,01810188 0,04163432 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01810188 0,04159273 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01810188 0,04155122 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01810188 0,04150979 ! virus-host interaction GO:0019048 17 11 0,000 0,01810188 0,04146845 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01810188 0,04142718 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01810188 0,041386 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01810188 0,0413449 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01810188 0,04130389 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01810188 0,04126295 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01810188 0,0412221 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01810188 0,04118132 ! mating GO:0007618 14 11 0,000 0,01810188 0,04114063 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01810188 0,04110002 ! T cell proliferation GO:0042098 20 11 0,000 0,01810188 0,04105949 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01810188 0,04101903 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01810188 0,04097866 ! bone resorption GO:0045453 16 11 0,000 0,01810188 0,04093837 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01810188 0,04089815 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01810188 0,04085802 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01810188 0,04081796 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01810188 0,04077798 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01810188 0,04073808 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01810188 0,04069826 ! syncytium formation GO:0006949 15 11 0,000 0,01810188 0,04065851 ! plasma membrane organization GO:0007009 18 11 0,000 0,01810188 0,04061885 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01810188 0,04057926 ! focal adhesion formation GO:0048041 24 11 0,000 0,01810188 0,04053975 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01810188 0,04050031 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01810188 0,04046095 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01810188 0,04042167 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01810188 0,04038246 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01810188 0,04034333 ! adult heart development GO:0007512 11 11 0,000 0,01810188 0,04030428 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01810188 0,0402653 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01810188 0,0402264 ! temperature homeostasis GO:0001659 16 11 0,000 0,01810188 0,04018757 ! L-glutamate transport GO:0015813 16 11 0,000 0,01810188 0,04014881 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01810188 0,04011013 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01810188 0,04007153 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01810188 0,040033 ! stem cell development GO:0048864 29 11 0,000 0,01810188 0,03999454 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01810188 0,03995616 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01810188 0,03991785 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01810188 0,03987962 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01810188 0,03984145 ! vasoconstriction GO:0042310 15 11 0,000 0,01810188 0,03980336 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01810188 0,03976535 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01810188 0,0397274 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01810188 0,03968953 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01810188 0,03965173 ! ribosome assembly GO:0042255 13 11 0,000 0,01810188 0,039614 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01810188 0,03957635 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01810188 0,03953876 ! chromatin silencing GO:0006342 19 11 0,000 0,01810188 0,03950125 ! nucleosome positioning GO:0016584 13 11 0,000 0,01810188 0,03946381 ! T cell homeostasis GO:0043029 20 11 0,000 0,01810188 0,03942644 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01810188 0,03938914 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01810188 0,03935191 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01810188 0,03931475 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01810188 0,03927766 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01810188 0,03924064 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01810188 0,03920369 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01810188 0,03916681 ! oxygen transport GO:0015671 15 11 0,000 0,01810188 0,03913 ! male genitalia development GO:0030539 13 11 0,000 0,01810188 0,03909326 ! cholesterol efflux GO:0033344 19 11 0,000 0,01810188 0,03905658 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01810188 0,03901998 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01810188 0,03898344 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01810188 0,03894698 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01810188 0,03891058 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01810188 0,03887425 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01810188 0,03883798 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01810188 0,03880179 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01810188 0,03876566 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01810188 0,0387296 ! lysogeny GO:0030069 18 11 0,000 0,01810188 0,03869361 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01810188 0,03865768 ! acrosome reaction GO:0007340 13 11 0,000 0,01810188 0,03862182 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01810188 0,03858602 ! lactation GO:0007595 20 12 0,000 0,01973172 0,04202126 ! reproductive cellular process GO:0048610 14 12 0,000 0,01973172 0,04198239 ! tRNA modification GO:0006400 14 12 0,000 0,01973172 0,04194359 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01973172 0,04190486 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01973172 0,0418662 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01973172 0,04182762 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01973172 0,0417891 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01973172 0,04175066 ! non-recombinational repair GO:0000726 19 12 0,000 0,01973172 0,04171228 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01973172 0,04167398 ! peroxisomal transport GO:0043574 21 12 0,000 0,01973172 0,04163575 ! cartilage condensation GO:0001502 18 12 0,000 0,01973172 0,04159759 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01973172 0,04155949 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01973172 0,04152147 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01973172 0,04148352 ! heart looping GO:0001947 15 12 0,000 0,01973172 0,04144563 ! palate development GO:0060021 15 12 0,000 0,01973172 0,04140782 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01973172 0,04137007 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01973172 0,04133239 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01973172 0,04129478 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01973172 0,04125724 ! arginine metabolic process GO:0006525 13 12 0,000 0,01973172 0,04121977 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01973172 0,04118236 ! methionine metabolic process GO:0006555 13 12 0,000 0,01973172 0,04114503 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01973172 0,04110776 ! Golgi organization GO:0007030 18 12 0,000 0,01973172 0,04107056 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01973172 0,04103342 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01973172 0,04099636 ! monoamine transport GO:0015844 13 12 0,000 0,01973172 0,04095936 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01973172 0,04092242 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01973172 0,04088555 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01973172 0,04084875 ! L-amino acid transport GO:0015807 20 12 0,000 0,01973172 0,04081202 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01973172 0,04077535 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01973172 0,04073875 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01973172 0,04070221 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01973172 0,04066574 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01973172 0,04062933 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01973172 0,04059299 ! cerebellum development GO:0021549 13 12 0,000 0,01973172 0,04055672 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01973172 0,04052051 ! histone acetylation GO:0016573 23 12 0,000 0,01973172 0,04048436 ! histone methylation GO:0016571 15 12 0,000 0,01973172 0,04044828 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01973172 0,04041226 ! gland morphogenesis GO:0022612 23 12 0,000 0,01973172 0,0403763 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01973172 0,04034041 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01973172 0,04030459 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01973172 0,04026883 ! response to gamma radiation GO:0010332 20 12 0,000 0,01973172 0,04023313 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01973172 0,04019749 ! intestinal absorption GO:0050892 19 12 0,000 0,01973172 0,04016192 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01973172 0,04012641 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01973172 0,04009096 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01973172 0,04005557 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01973172 0,04002025 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01973172 0,03998499 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01973172 0,03994979 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01973172 0,03991466 ! microspike assembly GO:0030035 23 12 0,000 0,01973172 0,03987958 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01973172 0,03984457 ! response to cold GO:0009409 14 12 0,000 0,01973172 0,03980962 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02135896 0,04305487 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02135896 0,04301717 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02135896 0,04297953 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02135896 0,04294196 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02135896 0,04290446 ! water transport GO:0006833 17 13 0,000 0,02135896 0,04286702 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02135896 0,04282965 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02135896 0,04279234 ! lipid localization GO:0010876 24 13 0,000 0,02135896 0,0427551 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02135896 0,04271792 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02135896 0,0426808 ! organelle fusion GO:0048284 28 13 0,000 0,02135896 0,04264375 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02135896 0,04260677 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02135896 0,04256985 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02135896 0,04253299 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02135896 0,0424962 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02135896 0,04245947 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02135896 0,0424228 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02135896 0,0423862 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02135896 0,04234966 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02135896 0,04231318 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02135896 0,04227677 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02135896 0,04224042 ! NAD metabolic process GO:0019674 21 13 0,000 0,02135896 0,04220413 ! exocrine system development GO:0035272 27 13 0,000 0,02135896 0,0421679 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02135896 0,04213174 ! bone mineralization GO:0030282 15 13 0,000 0,02135896 0,04209563 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02135896 0,04205959 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02135896 0,04202361 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02135896 0,0419877 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02135896 0,04195184 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02135896 0,04191604 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02135896 0,04188031 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02135896 0,04184464 ! genitalia development GO:0048806 15 13 0,000 0,02135896 0,04180902 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02135896 0,04177347 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02135896 0,04173798 ! cellular pigmentation GO:0033059 24 13 0,000 0,02135896 0,04170255 ! tissue regeneration GO:0042246 21 13 0,000 0,02135896 0,04166718 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02135896 0,04163187 ! cofactor transport GO:0051181 19 13 0,000 0,02135896 0,04159662 ! NADP metabolic process GO:0006739 18 13 0,000 0,02135896 0,04156142 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02135896 0,04152629 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02135896 0,04149122 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02135896 0,04145621 ! gas transport GO:0015669 18 13 0,000 0,02135896 0,04142125 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02135896 0,04138636 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02135896 0,04135152 ! regulation of axon extension GO:0030516 23 13 0,000 0,02135896 0,04131674 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02135896 0,04128202 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02135896 0,04124736 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02135896 0,04121276 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02135896 0,04117821 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02135896 0,04114372 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02135896 0,04110929 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02298358 0,0441992 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02298358 0,04416228 ! superoxide anion generation GO:0042554 18 14 0,000 0,02298358 0,04412541 ! neuron maturation GO:0042551 21 14 0,000 0,02298358 0,04408861 ! regulation of S phase GO:0033261 18 14 0,000 0,02298358 0,04405187 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02298358 0,04401519 ! myotube differentiation GO:0014902 21 14 0,000 0,02298358 0,04397857 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02298358 0,04394201 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02298358 0,04390552 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02298358 0,04386908 ! inositol metabolic process GO:0006020 20 14 0,000 0,02298358 0,04383271 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02298358 0,04379639 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02298358 0,04376014 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02298358 0,04372394 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02298358 0,0436878 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02298358 0,04365173 ! response to cAMP GO:0051591 19 14 0,000 0,02298358 0,04361571 ! limbic system development GO:0021761 25 14 0,000 0,02298358 0,04357976 ! startle response GO:0001964 21 14 0,000 0,02298358 0,04354386 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02298358 0,04350802 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02298358 0,04347224 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02298358 0,04343652 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02298358 0,04340086 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02298358 0,04336525 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02298358 0,04332971 ! glycine metabolic process GO:0006544 22 14 0,000 0,02298358 0,04329422 ! pituitary gland development GO:0021983 23 14 0,000 0,02298358 0,04325879 ! cellular response to starvation GO:0009267 21 14 0,000 0,02298358 0,04322342 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02298358 0,04318811 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02298358 0,04315285 ! regulation of heart rate GO:0002027 23 14 0,000 0,02298358 0,04311765 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02298358 0,04308251 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02298358 0,04304743 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02298358 0,0430124 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02298358 0,04297743 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02298358 0,04294252 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02298358 0,04290767 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02298358 0,04287287 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02298358 0,04283812 ! axon cargo transport GO:0008088 27 14 0,000 0,02298358 0,04280344 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02298358 0,04276881 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02298358 0,04273423 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02298358 0,04269971 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02298358 0,04266525 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02298358 0,04263084 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02298358 0,04259649 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02298358 0,04256219 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02298358 0,04252795 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02298358 0,04249377 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02298358 0,04245963 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02298358 0,04242556 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02298358 0,04239153 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02298358 0,04235757 ! muscle maintenance GO:0046716 19 14 0,000 0,02298358 0,04232365 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02298358 0,0422898 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02298358 0,04225599 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02298358 0,04222224 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02298358 0,04218854 ! cell killing GO:0001906 20 14 0,000 0,02298358 0,0421549 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02298358 0,04212131 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02298358 0,04208777 ! cilium assembly GO:0042384 20 14 0,000 0,02298358 0,04205429 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02298358 0,04202086 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02460561 0,04495067 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02460561 0,044915 ! metencephalon development GO:0022037 19 15 0,000 0,02460561 0,04487938 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02460561 0,04484381 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02460561 0,04480831 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02460561 0,04477286 ! skin development GO:0043588 25 15 0,000 0,02460561 0,04473747 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02460561 0,04470213 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02460561 0,04466685 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02460561 0,04463162 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02460561 0,04459645 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02460561 0,04456133 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02460561 0,04452627 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02460561 0,04449127 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02460561 0,04445632 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02460561 0,04442142 ! adult walking behavior GO:0007628 25 15 0,000 0,02460561 0,04438658 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02460561 0,0443518 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02460561 0,04431707 ! myoblast differentiation GO:0045445 27 15 0,000 0,02460561 0,04428239 ! centrosome cycle GO:0007098 16 15 0,000 0,02460561 0,04424777 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02460561 0,0442132 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02460561 0,04417868 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02460561 0,04414422 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02460561 0,04410982 ! cerebral cortex development GO:0021987 29 15 0,000 0,02460561 0,04407546 ! response to osmotic stress GO:0006970 22 15 0,000 0,02460561 0,04404116 ! vesicle coating GO:0006901 25 15 0,000 0,02460561 0,04400692 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02460561 0,04397272 ! DNA integration GO:0015074 22 15 0,000 0,02460561 0,04393858 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02460561 0,04390449 ! peptide secretion GO:0002790 27 15 0,000 0,02460561 0,04387046 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02460561 0,04383648 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02460561 0,04380255 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02460561 0,04376867 ! neuron recognition GO:0008038 22 15 0,000 0,02460561 0,04373485 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02460561 0,04370108 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02460561 0,04366736 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02460561 0,04363369 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02460561 0,04360007 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02460561 0,04356651 ! biomineral formation GO:0031214 18 15 0,000 0,02460561 0,043533 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02460561 0,04349953 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02460561 0,04346612 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02460561 0,04343277 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02460561 0,04339946 ! organic cation transport GO:0015695 19 15 0,000 0,02460561 0,0433662 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02460561 0,043333 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02460561 0,04329984 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02460561 0,04326674 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02460561 0,04323369 ! defense response to virus GO:0051607 27 15 0,000 0,02460561 0,04320068 ! peptide hormone processing GO:0016486 19 15 0,000 0,02460561 0,04316773 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02460561 0,04313483 ! protein secretion GO:0009306 27 16 0,000 0,02622503 0,04593874 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02622503 0,04590378 ! hormone secretion GO:0046879 25 16 0,000 0,02622503 0,04586887 ! bone remodeling GO:0046849 24 16 0,000 0,02622503 0,04583401 ! endothelial cell migration GO:0043542 22 16 0,000 0,02622503 0,04579921 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02622503 0,04576446 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02622503 0,04572977 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02622503 0,04569512 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02622503 0,04566053 ! glial cell development GO:0021782 24 16 0,000 0,02622503 0,04562599 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02622503 0,04559151 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02622503 0,04555707 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02622503 0,04552269 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02622503 0,04548836 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02622503 0,04545408 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02622503 0,04541985 ! fructose metabolic process GO:0006000 20 16 0,000 0,02622503 0,04538568 ! regulation of protein binding GO:0043393 27 16 0,000 0,02622503 0,04535155 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02622503 0,04531748 ! protein export from nucleus GO:0006611 24 16 0,000 0,02622503 0,04528346 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02622503 0,04524949 ! DNA replication initiation GO:0006270 25 16 0,000 0,02622503 0,04521556 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02622503 0,0451817 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02622503 0,04514788 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02622503 0,04511411 ! diencephalon development GO:0021536 25 16 0,000 0,02622503 0,04508039 ! oogenesis GO:0048477 23 16 0,000 0,02622503 0,04504672 ! neural crest cell migration GO:0001755 24 16 0,000 0,02622503 0,04501311 ! G1 phase GO:0051318 27 16 0,000 0,02622503 0,04497954 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02622503 0,04494602 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02622503 0,04491256 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02622503 0,04487914 ! steroid catabolic process GO:0006706 22 16 0,000 0,02622503 0,04484577 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02622503 0,04481245 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02622503 0,04477919 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02622503 0,04474597 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02622503 0,0447128 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02622503 0,04467968 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02622503 0,04464661 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,02622503 0,04461358 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02622503 0,04458061 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02622503 0,04454768 ! negative regulation of translation GO:0017148 22 16 0,000 0,02622503 0,04451481 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02784185 0,04722438 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02784185 0,04718958 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02784185 0,04715483 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02784185 0,04712013 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02784185 0,04708549 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02784185 0,04705089 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02784185 0,04701635 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02784185 0,04698185 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02784185 0,04694741 ! signal complex assembly GO:0007172 29 17 0,000 0,02784185 0,04691301 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02784185 0,04687867 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02784185 0,04684438 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02784185 0,04681013 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02784185 0,04677594 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02784185 0,0467418 ! memory GO:0007613 25 17 0,000 0,02784185 0,0467077 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02784185 0,04667366 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02784185 0,04663967 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02784185 0,04660572 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02784185 0,04657183 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02784185 0,04653798 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02784185 0,04650418 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02784185 0,04647044 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02784185 0,04643674 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02784185 0,04640309 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02784185 0,04636949 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02784185 0,04633594 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02784185 0,04630243 ! membrane budding GO:0006900 29 17 0,000 0,02784185 0,04626898 ! heme metabolic process GO:0042168 27 17 0,000 0,02784185 0,04623557 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02784185 0,04620221 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02784185 0,0461689 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02784185 0,04613564 ! body fluid secretion GO:0007589 27 17 0,000 0,02784185 0,04610242 ! stem cell differentiation GO:0048863 36 17 0,000 0,02784185 0,04606925 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02784185 0,04603613 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02784185 0,04600306 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02784185 0,04597004 ! sensory perception of pain GO:0019233 23 17 0,000 0,02784185 0,04593706 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02784185 0,04590413 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02784185 0,04587125 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02784185 0,04583841 ! synaptogenesis GO:0007416 24 17 0,000 0,02784185 0,04580562 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02784185 0,04577288 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02784185 0,04574019 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02784185 0,04570754 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02784185 0,04567494 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02784185 0,04564238 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02784185 0,04560987 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02784185 0,04557741 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02784185 0,04554499 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02784185 0,04551262 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02784185 0,0454803 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02945609 0,04808304 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02945609 0,04804894 ! positive regulation of translation GO:0045727 28 18 0,000 0,02945609 0,04801488 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02945609 0,04798088 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02945609 0,04794692 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02945609 0,04791301 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02945609 0,04787915 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02945609 0,04784534 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02945609 0,04781157 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02945609 0,04777786 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02945609 0,04774419 ! axis specification GO:0009798 26 18 0,000 0,02945609 0,04771056 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02945609 0,04767699 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02945609 0,04764346 ! pancreas development GO:0031016 26 18 0,000 0,02945609 0,04760998 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02945609 0,04757654 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02945609 0,04754316 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02945609 0,04750982 ! response to retinoic acid GO:0032526 25 18 0,000 0,02945609 0,04747652 ! pigmentation during development GO:0048066 31 18 0,000 0,02945609 0,04744328 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02945609 0,04741008 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02945609 0,04737692 ! fucose metabolic process GO:0006004 26 18 0,000 0,02945609 0,04734381 ! response to fungus GO:0009620 19 18 0,000 0,02945609 0,04731075 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02945609 0,04727774 ! heart process GO:0003015 27 18 0,000 0,02945609 0,04724477 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02945609 0,04721185 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02945609 0,04717897 ! visual learning GO:0008542 35 18 0,000 0,02945609 0,04714614 ! somitogenesis GO:0001756 24 18 0,000 0,02945609 0,04711335 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02945609 0,04708061 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02945609 0,04704792 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02945609 0,04701527 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02945609 0,04698266 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02945609 0,0469501 ! vitamin transport GO:0051180 24 18 0,000 0,02945609 0,04691759 ! hormone transport GO:0009914 27 18 0,000 0,02945609 0,04688512 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02945609 0,0468527 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02945609 0,04682032 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02945609 0,04678798 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02945609 0,04675569 ! cell-cell recognition GO:0009988 20 18 0,000 0,02945609 0,04672345 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02945609 0,04669125 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02945609 0,04665909 ! regulation of glucose import GO:0046324 21 18 0,000 0,02945609 0,04662698 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02945609 0,04659491 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02945609 0,04656289 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02945609 0,04653091 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02945609 0,04649897 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03106773 0,04900945 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03106773 0,04897586 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03106773 0,04894232 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03106773 0,04890882 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03106773 0,04887536 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03106773 0,04884196 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03106773 0,0488086 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03106773 0,04877528 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03106773 0,04874201 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03106773 0,04870878 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03106773 0,0486756 ! regeneration GO:0031099 32 19 0,000 0,03106773 0,04864247 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03106773 0,04860938 ! response to alkaloid GO:0043279 32 19 0,000 0,03106773 0,04857633 ! sensory perception of taste GO:0050909 23 19 0,000 0,03106773 0,04854333 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03106773 0,04851038 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03106773 0,04847746 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03106773 0,0484446 ! peroxisome organization GO:0007031 29 19 0,000 0,03106773 0,04841178 ! digestive system process GO:0022600 30 19 0,000 0,03106773 0,048379 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03106773 0,04834627 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03106773 0,04831358 ! response to vitamin A GO:0033189 26 19 0,000 0,03106773 0,04828093 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03106773 0,04824833 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03106773 0,04821578 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03106773 0,04818327 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03106773 0,0481508 ! response to starvation GO:0042594 30 19 0,000 0,03106773 0,04811837 ! sex determination GO:0007530 29 19 0,000 0,03106773 0,04808599 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03106773 0,04805365 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03106773 0,04802136 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03106773 0,04798911 ! cytolysis GO:0019835 20 19 0,000 0,03106773 0,0479569 ! renal system process GO:0003014 35 19 0,000 0,03106773 0,04792474 ! vasodilation GO:0042311 33 19 0,000 0,03106773 0,04789262 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03106773 0,04786054 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03106773 0,0478285 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03106773 0,04779651 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03106773 0,04776456 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03106773 0,04773265 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03106773 0,04770079 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03106773 0,04766897 ! sarcomere organization GO:0045214 23 19 0,000 0,03106773 0,04763719 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03106773 0,04760545 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03106773 0,04757376 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03106773 0,0475421 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03106773 0,04751049 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03106773 0,04747893 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03106773 0,0474474 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03106773 0,04741591 ! protein stabilization GO:0050821 26 19 0,000 0,03106773 0,04738447 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03267679 0,04980558 ! iron ion transport GO:0006826 37 20 0,000 0,03267679 0,0497726 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03267679 0,04973966 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03267679 0,04970676 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03267679 0,04967391 ! response to vitamin GO:0033273 29 20 0,000 0,03267679 0,0496411 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03267679 0,04960833 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03267679 0,04957561 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03267679 0,04954293 ! spinal cord development GO:0021510 31 20 0,000 0,03267679 0,04951029 ! response to ethanol GO:0045471 37 20 0,000 0,03267679 0,0494777 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03267679 0,04944515 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03267679 0,04941264 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03267679 0,04938017 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03267679 0,04934775 ! chromosome condensation GO:0030261 31 20 0,000 0,03267679 0,04931537 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03267679 0,04928303 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03267679 0,04925074 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03267679 0,04921848 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03267679 0,04918627 ! pallium development GO:0021543 38 20 0,000 0,03267679 0,0491541 ! DNA modification GO:0006304 28 20 0,000 0,03267679 0,04912198 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03267679 0,04908989 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03267679 0,04905785 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03267679 0,04902585 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03267679 0,04899389 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03267679 0,04896197 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,03267679 0,04893009 ! collagen catabolic process GO:0030574 25 20 0,000 0,03267679 0,04889826 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03267679 0,04886647 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03267679 0,04883471 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03267679 0,048803 ! alditol metabolic process GO:0019400 24 20 0,000 0,03267679 0,04877133 ! actin filament-based movement GO:0030048 34 20 0,000 0,03267679 0,0487397 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03428327 0,05110274 ! regulation of cell killing GO:0031341 34 21 0,000 0,03428327 0,05106964 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03428327 0,05103659 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,03428327 0,05100358 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03428327 0,05097061 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03428327 0,05093768 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03428327 0,0509048 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03428327 0,05087196 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03428327 0,05083916 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03428327 0,0508064 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03428327 0,05077368 ! protein amino acid acylation GO:0043543 37 21 0,000 0,03428327 0,05074101 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03428327 0,05070838 ! vesicle docking GO:0048278 27 21 0,000 0,03428327 0,05067579 ! phototransduction GO:0007602 25 21 0,000 0,03428327 0,05064324 ! dendrite development GO:0016358 35 21 0,000 0,03428327 0,05061074 ! visual behavior GO:0007632 39 21 0,000 0,03428327 0,05057827 ! ovarian follicle development GO:0001541 30 21 0,000 0,03428327 0,05054585 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03428327 0,05051347 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03428327 0,05048113 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03428327 0,05044884 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03428327 0,05041658 ! cell aging GO:0007569 32 21 0,000 0,03428327 0,05038436 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03428327 0,05035219 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03428327 0,05032006 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03428327 0,05028797 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03428327 0,05025591 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03428327 0,0502239 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03428327 0,05019194 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03428327 0,05016001 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,03428327 0,05012812 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03428327 0,05009627 ! fatty acid transport GO:0015908 30 21 0,000 0,03428327 0,05006446 ! platelet activation GO:0030168 28 21 0,000 0,03428327 0,0500327 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03428327 0,05000097 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03428327 0,04996928 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03428327 0,04993764 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,03428327 0,04990603 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03428327 0,04987447 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03428327 0,04984294 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03428327 0,04981145 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03428327 0,04978001 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03428327 0,0497486 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03428327 0,04971723 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03428327 0,0496859 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03428327 0,04965462 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03428327 0,04962337 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03428327 0,04959216 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03588718 0,05187964 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03588718 0,05184706 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03588718 0,05181451 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03588718 0,051782 ! viral genome replication GO:0019079 29 22 0,000 0,03588718 0,05174954 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03588718 0,05171711 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03588718 0,05168473 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03588718 0,05165239 ! molting cycle process GO:0022404 40 22 0,000 0,03588718 0,05162008 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03588718 0,05158782 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03588718 0,0515556 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03588718 0,05152342 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03588718 0,05149127 ! vasculogenesis GO:0001570 33 22 0,000 0,03588718 0,05145917 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03588718 0,05142711 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03588718 0,05139509 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03588718 0,05136311 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03588718 0,05133116 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03588718 0,05129926 ! lysosome organization GO:0007040 37 22 0,000 0,03588718 0,0512674 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03588718 0,05123558 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03588718 0,05120379 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03588718 0,05117205 ! regulation of behavior GO:0050795 38 22 0,000 0,03588718 0,05114034 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03588718 0,05110868 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03588718 0,05107705 ! membrane depolarization GO:0051899 35 22 0,000 0,03588718 0,05104546 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03588718 0,05101391 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03588718 0,0509824 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03588718 0,05095093 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03588718 0,0509195 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03588718 0,05088811 ! blastocyst development GO:0001824 37 22 0,000 0,03588718 0,05085675 ! neural tube closure GO:0001843 33 22 0,000 0,03588718 0,05082544 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03588718 0,05079416 ! protein tetramerization GO:0051262 39 22 0,000 0,03588718 0,05076292 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,03748851 0,05299544 ! neuron fate commitment GO:0048663 32 23 0,000 0,03748851 0,05296289 ! embryonic pattern specification GO:0009880 31 23 0,000 0,03748851 0,05293037 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,03748851 0,0528979 ! myelination GO:0042552 35 23 0,000 0,03748851 0,05286547 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,03748851 0,05283307 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,03748851 0,05280072 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,03748851 0,05276841 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,03748851 0,05273613 ! vesicle targeting GO:0006903 32 23 0,000 0,03748851 0,0527039 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,03748851 0,0526717 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,03748851 0,05263955 ! osteoblast differentiation GO:0001649 40 23 0,000 0,03748851 0,05260743 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,03748851 0,05257535 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,03748851 0,05254331 ! interaction with host GO:0051701 37 23 0,000 0,03748851 0,05251131 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,03748851 0,05247935 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,03748851 0,05244743 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,03748851 0,05241555 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,03748851 0,0523837 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,03748851 0,0523519 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,03748851 0,05232013 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,03748851 0,0522884 ! cell fate determination GO:0001709 45 23 0,000 0,03748851 0,05225671 ! pentose metabolic process GO:0019321 31 23 0,000 0,03748851 0,05222506 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,03748851 0,05219345 ! spermatid development GO:0007286 33 23 0,000 0,03748851 0,05216187 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,03748851 0,05213034 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,03748851 0,05209884 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,03748851 0,05206738 ! telomere organization GO:0032200 32 23 0,000 0,03748851 0,05203596 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,03748851 0,05200457 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,03748851 0,05197322 ! regulation of amine transport GO:0051952 38 23 0,000 0,03748851 0,05194191 ! liver development GO:0001889 40 23 0,000 0,03748851 0,05191064 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03908728 0,0540919 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03908728 0,05405937 ! initiation of viral infection GO:0019059 42 24 0,000 0,03908728 0,05402688 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03908728 0,05399444 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03908728 0,05396203 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03908728 0,05392966 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03908728 0,05389732 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03908728 0,05386503 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03908728 0,05383278 ! sperm motility GO:0030317 27 24 0,000 0,03908728 0,05380056 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03908728 0,05376838 ! vacuole organization GO:0007033 39 24 0,000 0,03908728 0,05373624 ! receptor metabolic process GO:0043112 37 24 0,000 0,03908728 0,05370414 ! neural crest cell development GO:0014032 39 24 0,000 0,03908728 0,05367208 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03908728 0,05364006 ! primary neural tube formation GO:0014020 35 24 0,000 0,03908728 0,05360807 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03908728 0,05357612 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03908728 0,05354421 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03908728 0,05351234 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03908728 0,05348051 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03908728 0,05344871 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03908728 0,05341696 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03908728 0,05338524 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03908728 0,05335355 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03908728 0,05332191 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04068348 0,05546651 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04068348 0,05543365 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04068348 0,05540083 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04068348 0,05536805 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04068348 0,0553353 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04068348 0,0553026 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,04068348 0,05526993 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04068348 0,05523731 ! peptide transport GO:0015833 43 25 0,000 0,04068348 0,05520472 ! male gonad development GO:0008584 33 25 0,000 0,04068348 0,05517217 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04068348 0,05513966 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04068348 0,05510718 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04068348 0,05507475 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04068348 0,05504235 ! phospholipid transport GO:0015914 35 25 0,000 0,04068348 0,05500999 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04068348 0,05497767 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04068348 0,05494539 ! detection of light stimulus GO:0009583 30 25 0,000 0,04068348 0,05491314 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04068348 0,05488094 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04068348 0,05484877 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04068348 0,05481664 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04068348 0,05478454 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,04227712 0,05689723 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,04227712 0,05686396 ! translational initiation GO:0006413 43 26 0,000 0,04227712 0,05683073 ! regulation of pH GO:0006885 36 26 0,000 0,04227712 0,05679753 ! circadian rhythm GO:0007623 42 26 0,000 0,04227712 0,05676437 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,04227712 0,05673125 ! post-embryonic development GO:0009791 42 26 0,000 0,04227712 0,05669818 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,04227712 0,05666513 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,04227712 0,05663213 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,04227712 0,05659917 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,04227712 0,05656624 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,04227712 0,05653335 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,04227712 0,05650051 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,04227712 0,05646769 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,04227712 0,05643492 ! regulation of coagulation GO:0050818 39 26 0,000 0,04227712 0,05640219 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0438682 0,05849094 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0438682 0,05845705 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0438682 0,0584232 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0438682 0,05838939 ! membrane docking GO:0022406 39 27 0,000 0,0438682 0,05835562 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0438682 0,05832189 ! catechol metabolic process GO:0009712 43 27 0,000 0,0438682 0,05828819 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! acute-phase response GO:0006953 42 27 0,000 0,0438682 0,05825454 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0438682 0,05822093 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0438682 0,05818735 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0438682 0,05815381 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0438682 0,05812031 ! natural killer cell activation GO:0030101 35 27 0,000 0,0438682 0,05808685 ! lipid oxidation GO:0034440 38 27 0,000 0,0438682 0,05805343 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0438682 0,05802005 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0438682 0,0579867 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0438682 0,0579534 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0438682 0,05792013 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0438682 0,0578869 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0438682 0,05785371 ! gene silencing GO:0016458 41 27 0,000 0,0438682 0,05782055 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,04545673 0,05988 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,04545673 0,05984573 ! phenol metabolic process GO:0018958 44 28 0,000 0,04545673 0,05981149 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,04545673 0,05977729 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,04545673 0,05974314 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,04545673 0,05970902 ! cell junction assembly GO:0034329 56 28 0,000 0,04545673 0,05967494 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,04545673 0,05964089 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,04545673 0,05960689 GO:0055092|sterol homeostasis, ! complement activation, classical pathway GO:0006958 36 28 0,000 0,04545673 0,05957293 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,04545673 0,059539 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,04545673 0,05950511 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,04545673 0,05947127 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,04545673 0,05943746 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,04545673 0,05940369 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,04545673 0,05936995 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,04545673 0,05933626 ! mesoderm formation GO:0001707 46 28 0,000 0,04545673 0,0593026 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,04545673 0,05926898 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,04545673 0,0592354 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,04545673 0,05920186 ! ensheathment of neurons GO:0007272 43 28 0,000 0,04545673 0,05916836 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,04545673 0,05913489 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,04545673 0,05910146 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,04545673 0,05906807 ! neural tube formation GO:0001841 41 28 0,000 0,04545673 0,05903472 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,04545673 0,0590014 ! placenta development GO:0001890 37 28 0,000 0,04545673 0,05896813 ! regulation of B cell activation GO:0050864 42 28 0,000 0,04545673 0,05893489 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04704272 0,06095676 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04704272 0,06092244 ! ovulation cycle process GO:0022602 41 29 0,000 0,04704272 0,06088815 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04704272 0,06085391 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04704272 0,0608197 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04704272 0,06078553 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04704272 0,0607514 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04704272 0,06071731 ! telencephalon development GO:0021537 52 29 0,000 0,04704272 0,06068326 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04704272 0,06064924 ! eye morphogenesis GO:0048592 51 29 0,000 0,04704272 0,06061527 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04704272 0,06058133 ! tissue homeostasis GO:0001894 42 29 0,000 0,04704272 0,06054743 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04862616 0,06255042 ! collagen metabolic process GO:0032963 40 30 0,000 0,04862616 0,06251546 ! organic anion transport GO:0015711 51 30 0,000 0,04862616 0,06248054 ! cholesterol transport GO:0030301 46 30 0,000 0,04862616 0,06244565 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04862616 0,0624108 ! spliceosome assembly GO:0000245 49 30 0,000 0,04862616 0,06237599 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04862616 0,06234123 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04862616 0,0623065 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04862616 0,0622718 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04862616 0,06223715 ! ovulation cycle GO:0042698 43 30 0,000 0,04862616 0,06220254 ! hindbrain development GO:0030902 45 30 0,000 0,04862616 0,06216796 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04862616 0,06213342 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04862616 0,06209892 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04862616 0,06206446 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04862616 0,06203004 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04862616 0,06199565 ! response to heat GO:0009408 41 30 0,000 0,04862616 0,06196131 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04862616 0,061927 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04862616 0,06189273 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05020705 0,06386959 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05020705 0,06383429 ! mammary gland development GO:0030879 57 31 0,000 0,05020705 0,06379902 ! glial cell differentiation GO:0010001 55 31 0,000 0,05020705 0,06376379 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05020705 0,0637286 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05020705 0,06369345 ! odontogenesis GO:0042476 50 31 0,000 0,05020705 0,06365834 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05020705 0,06362326 ! segmentation GO:0035282 41 31 0,000 0,05020705 0,06358823 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05020705 0,06355323 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05020705 0,06351828 ! metanephros development GO:0001656 58 31 0,000 0,05020705 0,06348336 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05020705 0,06344848 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05020705 0,06341363 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05020705 0,06337883 ! cell fate specification GO:0001708 37 31 0,000 0,05020705 0,06334406 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05020705 0,06330933 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05020705 0,06327464 ! RNA modification GO:0009451 40 31 0,000 0,05020705 0,06323999 ! regulation of muscle development GO:0048634 48 32 0,000 0,05178542 0,06519237 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,05178542 0,06515671 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,05178542 0,06512108 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,05178542 0,0650855 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,05178542 0,06504995 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,05178542 0,06501444 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,05178542 0,06497897 ! peripheral nervous system development GO:0007422 53 32 0,000 0,05178542 0,06494354 ! regulation of protein stability GO:0031647 48 32 0,000 0,05178542 0,06490815 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,05178542 0,0648728 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,05178542 0,06483748 ! cytokine production GO:0001816 44 32 0,000 0,05178542 0,06480221 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,05178542 0,06476697 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,05178542 0,06473177 ! vesicle localization GO:0051648 47 32 0,000 0,05178542 0,06469661 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,05336125 0,06662913 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,05336125 0,06659298 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,05336125 0,06655687 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,05336125 0,06652079 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,05336125 0,06648476 ! sister chromatid segregation GO:0000819 46 33 0,000 0,05336125 0,06644876 ! ear morphogenesis GO:0042471 42 33 0,000 0,05336125 0,06641281 ! cell junction organization GO:0034330 63 33 0,000 0,05336125 0,06637689 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,05336125 0,06634101 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,05336125 0,06630517 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,05336125 0,06626937 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,05336125 0,0662336 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,05336125 0,06619788 ! female gonad development GO:0008585 49 33 0,000 0,05336125 0,06616219 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,05336125 0,06612654 ! positive regulation of cell development GO:0010720 54 33 0,000 0,05336125 0,06609093 ! lipid homeostasis GO:0055088 55 33 0,000 0,05336125 0,06605536 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,05336125 0,06601983 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,05336125 0,06598434 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,05336125 0,06594888 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,05336125 0,06591346 ! cytokinesis GO:0000910 52 33 0,000 0,05336125 0,06587808 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,05336125 0,06584274 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,05493455 0,0677477 ! mRNA catabolic process GO:0006402 48 34 0,000 0,05493455 0,06771139 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,05493455 0,06767512 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,05493455 0,0676389 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,05493455 0,06760271 ! feeding behavior GO:0007631 45 34 0,000 0,05493455 0,06756655 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,05493455 0,06753044 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,05493455 0,06749437 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,05493455 0,06745833 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,05493455 0,06742234 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,05493455 0,06738638 ! neuron migration GO:0001764 46 34 0,000 0,05493455 0,06735046 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,05493455 0,06731457 ! female gamete generation GO:0007292 43 34 0,000 0,05493455 0,06727873 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,05493455 0,06724293 ! polyol metabolic process GO:0019751 44 34 0,000 0,05493455 0,06720716 ! aerobic respiration GO:0009060 47 34 0,000 0,05493455 0,06717143 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,05493455 0,06713574 ! embryonic organ development GO:0048568 45 34 0,000 0,05493455 0,06710008 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,05493455 0,06706447 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,05650532 0,06894549 ! Notch signaling pathway GO:0007219 56 35 0,000 0,05650532 0,06890893 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,05650532 0,06887241 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,05650532 0,06883593 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,05650532 0,06879949 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,05650532 0,06876309 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,05650532 0,06872673 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,05650532 0,0686904 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,05650532 0,06865412 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,05650532 0,06861787 ! glycogen metabolic process GO:0005977 48 35 0,000 0,05650532 0,06858166 ! pigment metabolic process GO:0042440 61 35 0,000 0,05650532 0,06854549 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,05650532 0,06850935 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,05650532 0,06847326 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05807358 0,07033661 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05807358 0,07029959 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05807358 0,07026261 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05807358 0,07022567 ! negative regulation of binding GO:0051100 58 36 0,000 0,05807358 0,07018877 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05807358 0,07015191 ! tissue remodeling GO:0048771 62 36 0,000 0,05807358 0,07011508 ! neural tube development GO:0021915 50 36 0,000 0,05807358 0,07007829 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05807358 0,07004155 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05807358 0,07000484 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05807358 0,06996817 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05807358 0,06993153 ! glucan metabolic process GO:0044042 49 36 0,000 0,05807358 0,06989494 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05963932 0,07174185 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05963932 0,07170435 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05963932 0,07166689 ! learning GO:0007612 67 37 0,000 0,05963932 0,07162947 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05963932 0,07159208 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05963932 0,07155473 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05963932 0,07151743 ! amino acid activation GO:0043038 52 37 0,000 0,05963932 0,07148016 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05963932 0,07144293 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06120254 0,07327738 ! gliogenesis GO:0042063 71 38 0,000 0,06120254 0,07323925 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06120254 0,07320117 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06120254 0,07316312 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06120254 0,07312511 ! phagocytosis GO:0006909 60 38 0,000 0,06120254 0,07308715 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06120254 0,07304922 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06120254 0,07301133 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06120254 0,07297348 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,06276326 0,07479559 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,06276326 0,07475686 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,06276326 0,07471816 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,06276326 0,07467951 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,06276326 0,07464089 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,06276326 0,07460232 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,06276326 0,07456379 ! male sex differentiation GO:0046661 53 39 0,000 0,06276326 0,07452529 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,06276326 0,07448684 ! chromatin remodeling GO:0006338 68 39 0,000 0,06276326 0,07444842 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,06276326 0,07441005 ! JNK cascade GO:0007254 54 39 0,000 0,06276326 0,07437171 ! developmental growth GO:0048589 62 39 0,000 0,06276326 0,07433341 ! cell growth GO:0016049 61 39 0,000 0,06276326 0,07429516 ! synapse organization GO:0050808 55 39 0,000 0,06276326 0,07425694 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,06432147 0,07606137 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,06432147 0,07602229 ! regulation of tube size GO:0035150 60 40 0,000 0,06432147 0,07598324 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,06432147 0,07594424 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,06432147 0,07590527 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,06432147 0,07586635 ! peptide metabolic process GO:0006518 56 40 0,000 0,06432147 0,07582746 ! inner ear development GO:0048839 57 40 0,000 0,06432147 0,07578861 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,06432147 0,07574981 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,06432147 0,07571104 ! B cell differentiation GO:0030183 62 40 0,000 0,06432147 0,07567231 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,06432147 0,07563363 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,06432147 0,07559498 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,06587718 0,07738381 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,06587718 0,07734431 ! glucose transport GO:0015758 52 41 0,000 0,06587718 0,07730485 ! endosome transport GO:0016197 71 41 0,000 0,06587718 0,07726543 ! striated muscle contraction GO:0006941 62 41 0,000 0,06587718 0,07722605 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,06587718 0,07718671 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,06587718 0,07714741 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,06587718 0,07710814 ! biopolymer methylation GO:0043414 62 41 0,000 0,06587718 0,07706892 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,06587718 0,07702974 ! mitochondrial transport GO:0006839 60 42 0,000 0,06743039 0,07880584 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,06743039 0,07876582 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,06743039 0,07872583 ! cellular component disassembly GO:0022411 64 42 0,000 0,06743039 0,07868589 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,06743039 0,07864599 ! hexose transport GO:0008645 54 42 0,000 0,06743039 0,07860613 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,06743039 0,07856631 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,06743039 0,07852653 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,06743039 0,07848679 ! excretion GO:0007588 63 42 0,000 0,06743039 0,07844709 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,06743039 0,07840743 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,06743039 0,07836781 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,06743039 0,07832823 ! regulation of cell shape GO:0008360 78 42 0,000 0,06743039 0,07828869 ! positive regulation of binding GO:0051099 59 43 0,000 0,06898111 0,08004871 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,06898111 0,08000834 ! leukocyte migration GO:0050900 60 43 0,000 0,06898111 0,07996802 ! neuromuscular process GO:0050905 79 43 0,000 0,06898111 0,07992773 ! activation of caspase activity GO:0006919 65 43 0,000 0,06898111 0,07988748 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,06898111 0,07984728 ! tRNA processing GO:0008033 49 43 0,000 0,06898111 0,07980711 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,06898111 0,07976699 ! vesicle organization GO:0016050 79 43 0,000 0,06898111 0,07972691 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,06898111 0,07968686 ! methylation GO:0032259 64 43 0,000 0,06898111 0,07964686 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07052933 0,08139361 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07052933 0,08135279 ! glycolysis GO:0006096 53 44 0,000 0,07052933 0,08131201 ! regulation of action potential GO:0001508 71 44 0,000 0,07052933 0,08127128 ! regulation of ion transport GO:0043269 57 44 0,000 0,07052933 0,08123058 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07052933 0,08118992 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07052933 0,08114931 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07052933 0,08110873 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07052933 0,0810682 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07052933 0,08102771 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07052933 0,08098725 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07052933 0,08094684 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,07052933 0,08090647 ! RNA catabolic process GO:0006401 64 45 0,000 0,07207508 0,08263842 ! positive regulation of defense response GO:0031349 59 45 0,000 0,07207508 0,08259725 ! regulation of translational initiation GO:0006446 64 45 0,000 0,07207508 0,08255611 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,07207508 0,08251502 ! cell recognition GO:0008037 58 45 0,000 0,07207508 0,08247397 ! cell maturation GO:0048469 60 45 0,000 0,07207508 0,08243296 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,07207508 0,08239198 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,07361834 0,08411434 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,07361834 0,08407258 ! cell redox homeostasis GO:0045454 63 46 0,000 0,07361834 0,08403085 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,07361834 0,08398917 ! regulation of ossification GO:0030278 71 46 0,000 0,07361834 0,08394753 ! histone modification GO:0016570 68 46 0,000 0,07361834 0,08390593 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,07361834 0,08386437 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,07515912 0,08557721 ! viral infectious cycle GO:0019058 71 47 0,000 0,07515912 0,08553487 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,07515912 0,08549257 ! endocrine system development GO:0035270 83 47 0,000 0,07515912 0,08545031 ! covalent chromatin modification GO:0016569 75 47 0,000 0,07515912 0,08540809 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,07515912 0,08536591 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,07515912 0,08532378 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,07515912 0,08528168 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,07515912 0,08523963 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,07515912 0,08519762 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,07515912 0,08515565 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,07515912 0,08511372 ! chloride transport GO:0006821 67 48 0,000 0,07669742 0,08681303 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,07669742 0,08677033 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,07669742 0,08672767 ! response to temperature stimulus GO:0009266 62 48 0,000 0,07669742 0,08668505 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,07669742 0,08664247 ! gastrulation GO:0007369 73 48 0,000 0,07669742 0,08659994 ! heart morphogenesis GO:0003007 65 48 0,000 0,07669742 0,08655745 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,07669742 0,086515 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,07669742 0,08647259 ! regulation of endocytosis GO:0030100 63 48 0,000 0,07669742 0,08643022 ! nuclear export GO:0051168 69 48 0,000 0,07669742 0,08638789 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,07669742 0,08634561 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,07669742 0,08630336 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,07823326 0,08798851 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,07823326 0,0879455 ! sensory perception of smell GO:0007608 61 49 0,000 0,07823326 0,08790254 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,07823326 0,08785962 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,07823326 0,08781674 ! RNA elongation GO:0006354 62 49 0,000 0,07823326 0,0877739 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,07823326 0,08773111 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,07823326 0,08768835 ! germ cell development GO:0007281 68 49 0,000 0,07823326 0,08764564 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,07823326 0,08760297 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,07823326 0,08756034 ! cartilage development GO:0051216 70 49 0,000 0,07823326 0,08751775 ! maintenance of location GO:0051235 84 49 0,000 0,07823326 0,08747521 ! ear development GO:0043583 72 50 0,000 0,07976663 0,08914638 ! membrane fusion GO:0006944 80 50 0,000 0,07976663 0,08910308 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,07976663 0,08905983 ! lipid modification GO:0030258 73 50 0,000 0,07976663 0,08901662 ! positive regulation of growth GO:0045927 67 50 0,000 0,07976663 0,08897345 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,07976663 0,08893032 ! proton transport GO:0015992 75 50 0,000 0,07976663 0,08888723 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,07976663 0,08884419 ! positive regulation of secretion GO:0051047 71 51 0,000 0,08129754 0,09050549 ! hydrogen transport GO:0006818 77 51 0,000 0,08129754 0,0904617 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,08129754 0,09041796 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,08129754 0,09037426 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,08129754 0,0903306 ! adult behavior GO:0030534 80 51 0,000 0,08129754 0,09028698 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,08129754 0,09024341 ! transition metal ion transport GO:0000041 74 52 0,000 0,08282598 0,09189569 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,08282598 0,09185138 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,08282598 0,09180712 ! establishment of organelle localization GO:0051656 85 52 0,000 0,08282598 0,09176289 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,08435198 0,09340854 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,08435198 0,09336359 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,08435198 0,09331869 ! kidney development GO:0001822 90 53 0,000 0,08435198 0,09327382 ! single fertilization GO:0007338 59 53 0,000 0,08435198 0,093229 ! cell projection assembly GO:0030031 76 53 0,000 0,08435198 0,09318422 ! amino acid transport GO:0006865 84 54 0,000 0,08587552 0,09482174 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,08587552 0,09477624 ! regulation of mitosis GO:0007088 84 54 0,000 0,08587552 0,09473079 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,08587552 0,09468537 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,08587552 0,09464001 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,08587552 0,09459468 ! DNA catabolic process GO:0006308 67 54 0,000 0,08587552 0,0945494 ! detection of external stimulus GO:0009581 66 54 0,000 0,08587552 0,09450416 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,08587552 0,09445896 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,08587552 0,09441381 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,08587552 0,0943687 ! exocytosis GO:0006887 74 55 0,000 0,08739661 0,09599437 ! mesoderm development GO:0007498 76 55 0,000 0,08739661 0,09594855 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,08739661 0,09590277 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,08739661 0,09585704 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,08891526 0,09747621 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,08891526 0,09742978 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,08891526 0,09738338 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,09043147 0,09899685 ! carbohydrate transport GO:0008643 74 57 0,000 0,09043147 0,09894975 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,09043147 0,0989027 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,09043147 0,09885569 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,09043147 0,09880873 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,09043147 0,09876181 ! camera-type eye development GO:0043010 88 57 0,000 0,09043147 0,09871494 ! secondary metabolic process GO:0019748 84 57 0,000 0,09043147 0,09866811 ! developmental maturation GO:0021700 75 57 0,000 0,09043147 0,09862133 ! gonad development GO:0008406 79 57 0,000 0,09043147 0,09857459 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,09194524 0,10017719 ! viral reproductive process GO:0022415 87 58 0,000 0,09194524 0,10012976 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,09194524 0,10008237 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,09194524 0,10003503 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,09194524 0,09998773 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,09345658 0,10158324 ! activation of MAPK activity GO:0000187 84 59 0,000 0,09345658 0,10153526 ! lung development GO:0030324 94 59 0,000 0,09345658 0,10148732 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,09345658 0,10143942 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,09345658 0,10139157 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,09496549 0,10298003 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,09496549 0,1029315 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,09496549 0,10288301 ! regulation of heart contraction GO:0008016 91 60 0,000 0,09496549 0,10283457 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,09496549 0,10278618 ! fertilization GO:0009566 68 60 0,000 0,09496549 0,10273783 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,09496549 0,10268953 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,09647198 0,10426953 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,09647198 0,10422055 ! urogenital system development GO:0001655 101 61 0,000 0,09647198 0,10417162 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,09647198 0,10412274 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,09647198 0,1040739 ! extracellular matrix organization GO:0030198 103 61 0,000 0,09647198 0,10402511 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,09647198 0,10397636 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,09647198 0,10392766 ! amine catabolic process GO:0009310 90 62 0,000 0,09797604 0,10549855 ! neurotransmitter transport GO:0006836 81 62 0,000 0,09797604 0,10544918 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,09797604 0,10539986 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,09797604 0,10535058 ! respiratory tube development GO:0030323 99 62 0,000 0,09797604 0,10530136 ! organelle localization GO:0051640 96 62 0,000 0,09797604 0,10525217 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,09947769 0,10681545 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,09947769 0,1067656 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,09947769 0,10671581 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,09947769 0,10666606 ! viral reproduction GO:0016032 92 63 0,000 0,09947769 0,10661635 ! regulation of lipase activity GO:0060191 109 63 0,000 0,09947769 0,10656669 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,10097692 0,10812241 ! negative regulation of cell size GO:0045792 108 64 0,000 0,10097692 0,10807209 ! appendage morphogenesis GO:0035107 93 64 0,000 0,10097692 0,10802183 GO:0035108|limb morphogenesis, ! hexose catabolic process GO:0019320 82 64 0,000 0,10097692 0,10797161 ! respiratory system development GO:0060541 100 64 0,000 0,10097692 0,10792143 ! reproductive structure development GO:0048608 90 65 0,000 0,10247375 0,10947033 ! regulation of caspase activity GO:0043281 97 65 0,000 0,10247375 0,10941951 ! appendage development GO:0048736 94 65 0,000 0,10247375 0,10936873 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,10247375 0,10931801 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,10247375 0,10926732 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,10247375 0,10921669 ! activation of immune response GO:0002253 83 65 0,000 0,10247375 0,1091661 ! protein oligomerization GO:0051259 100 65 0,000 0,10247375 0,10911556 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,10396816 0,11065561 ! antigen processing and presentation GO:0019882 96 66 0,000 0,10396816 0,11060443 ! axon guidance GO:0007411 99 66 0,000 0,10396816 0,1105533 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,10396816 0,11050221 ! regulation of immune effector process GO:0002697 101 66 0,000 0,10396816 0,11045117 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,10546018 0,11198449 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,10546018 0,11193282 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,10546018 0,11188119 ! acute inflammatory response GO:0002526 92 68 0,000 0,10694979 0,11340919 ! learning or memory GO:0007611 123 68 0,000 0,10694979 0,11335693 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,10694979 0,11330471 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,10694979 0,11325255 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,10694979 0,11320043 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,10694979 0,11314836 ! rhythmic process GO:0048511 105 68 0,000 0,10694979 0,11309633 ! inorganic anion transport GO:0015698 93 68 0,000 0,10694979 0,11304436 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,10843702 0,11456368 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,10843702 0,11451108 ! response to drug GO:0042493 108 69 0,000 0,10843702 0,11445853 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,10992184 0,11597259 ! humoral immune response GO:0006959 86 70 0,000 0,10992184 0,11591941 ! eye development GO:0001654 111 70 0,000 0,10992184 0,11586629 ! amine transport GO:0015837 101 70 0,000 0,10992184 0,11581321 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,10992184 0,11576018 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,11140429 0,11726767 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,11140429 0,11721402 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,11140429 0,11716043 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,11288434 0,1186627 ! response to hypoxia GO:0001666 132 72 0,000 0,11288434 0,11860849 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,11288434 0,11855433 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,11288434 0,11850022 ! negative regulation of transport GO:0051051 116 73 0,000 0,11436202 0,11999664 ! regulation of blood pressure GO:0008217 107 73 0,000 0,11436202 0,11994193 ! tube morphogenesis GO:0035239 118 73 0,000 0,11436202 0,11988726 ! mitochondrion organization GO:0007005 104 73 0,000 0,11436202 0,11983264 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,11436202 0,11977807 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,11436202 0,11972355 ! response to oxygen levels GO:0070482 137 74 0,000 0,11583732 0,12121285 ! digestion GO:0007586 97 74 0,000 0,11583732 0,12115772 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,11583732 0,12110265 ! negative regulation of growth GO:0045926 123 75 0,000 0,11731025 0,12258681 ! response to nutrient GO:0007584 104 75 0,000 0,11731025 0,12253114 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,11731025 0,12247552 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1187808 0,12395456 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1187808 0,12389835 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1187808 0,12384218 ! regulation of protein transport GO:0051223 114 76 0,000 0,1187808 0,12378607 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,120249 0,12525937 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,120249 0,12520267 ! regulation of DNA binding GO:0051101 119 77 0,000 0,120249 0,12514602 ! gland development GO:0048732 148 77 0,000 0,120249 0,12508941 ! sex differentiation GO:0007548 105 77 0,000 0,120249 0,12503286 ! protein ubiquitination GO:0016567 125 77 0,000 0,120249 0,12497636 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,120249 0,12491992 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,120249 0,12486352 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,120249 0,12480717 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,12171483 0,12627158 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,12171483 0,12621465 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1231783 0,12767467 ! cellular respiration GO:0045333 107 79 0,000 0,1231783 0,12761716 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1231783 0,1275597 ! T cell activation GO:0042110 134 79 0,000 0,1231783 0,12750229 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1231783 0,12744493 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1231783 0,12738763 ! chromatin assembly GO:0031497 102 80 0,000 0,12463942 0,12884075 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,12463942 0,12878287 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,12463942 0,12872504 ! forebrain development GO:0030900 131 80 0,000 0,12463942 0,12866726 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,12609818 0,13011477 ! mRNA transport GO:0051028 121 81 0,000 0,12609818 0,13005642 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,12609818 0,12999813 ! regulation of neurological system process GO:0031644 122 81 0,000 0,12609818 0,12993988 ! vitamin metabolic process GO:0006766 103 81 0,000 0,12609818 0,12988169 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,12609818 0,12982356 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,1275546 0,13126425 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1275546 0,13120554 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,12900868 0,13264191 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,12900868 0,13258265 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,12900868 0,13252343 ! regulation of defense response GO:0031347 117 84 0,000 0,13046041 0,13395489 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,13046041 0,13389512 ! sterol metabolic process GO:0016125 120 84 0,000 0,13046041 0,13383539 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,13190981 0,13526196 ! rRNA metabolic process GO:0016072 107 85 0,000 0,13190981 0,13520168 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,13190981 0,13514146 ! transcription initiation GO:0006352 118 85 0,000 0,13190981 0,13508129 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,13190981 0,13502117 ! regulation of protein localization GO:0032880 132 85 0,000 0,13190981 0,13496111 ! regulation of membrane potential GO:0042391 128 85 0,000 0,13190981 0,1349011 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,13190981 0,13484114 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,13335688 0,13625981 ! cell cycle arrest GO:0007050 150 86 0,000 0,13335688 0,1361993 ! nucleosome organization GO:0034728 114 87 0,000 0,13480162 0,13761372 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,13480162 0,13755267 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,13480162 0,13749167 ! female pregnancy GO:0007565 130 87 0,000 0,13480162 0,13743073 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,13480162 0,13736984 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,13624403 0,13877824 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,13624403 0,13871681 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,13624403 0,13865543 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,13624403 0,1385941 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,13624403 0,13853283 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,13768412 0,13993525 ! reproductive developmental process GO:0003006 127 89 0,000 0,13768412 0,13987344 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,13768412 0,13981169 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,13768412 0,13974999 ! regulation of T cell activation GO:0050863 128 89 0,000 0,13768412 0,13968834 ! leukocyte differentiation GO:0002521 143 90 0,000 0,13912189 0,14108481 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,13912189 0,14102263 ! hormone metabolic process GO:0042445 121 90 0,000 0,13912189 0,14096051 ! RNA localization GO:0006403 135 91 0,000 0,14055735 0,14235222 ! ATP metabolic process GO:0046034 137 91 0,000 0,14055735 0,14228957 ! response to virus GO:0009615 122 91 0,000 0,14055735 0,14222697 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,14199049 0,14361396 ! cell fate commitment GO:0045165 141 92 0,000 0,14199049 0,14355083 ! positive regulation of immune response GO:0050778 121 92 0,000 0,14199049 0,14348776 ! sulfur metabolic process GO:0006790 118 92 0,000 0,14199049 0,14342474 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,14342133 0,14480644 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,14342133 0,1447429 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,14342133 0,14467941 ! electron transport chain GO:0022900 123 94 0,000 0,14484987 0,14605642 ! response to oxidative stress GO:0006979 141 94 0,000 0,14484987 0,14599242 ! regulation of binding GO:0051098 151 95 0,000 0,1462761 0,14736532 ! angiogenesis GO:0001525 149 95 0,000 0,1462761 0,1473008 ! carboxylic acid transport GO:0046942 147 95 0,000 0,1462761 0,14723634 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,14770004 0,14860459 ! in utero embryonic development GO:0001701 147 96 0,000 0,14770004 0,14853961 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,14770004 0,14847469 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,14770004 0,14840982 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,14770004 0,14834501 ! protein maturation GO:0051604 129 96 0,000 0,14770004 0,14828026 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,14912168 0,14964217 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,14912168 0,14957691 ! calcium ion transport GO:0006816 167 99 0,000 0,1519581 0,15235555 ! extracellular structure organization GO:0043062 156 99 0,000 0,1519581 0,15228917 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,1519581 0,15222284 ! regulation of translation GO:0006417 151 100 0,000 0,15337289 0,1535732 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,15337289 0,15350637 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,15337289 0,1534396 ! divalent metal ion transport GO:0070838 171 100 0,000 0,15337289 0,15337289