pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/5155-5-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 6,605E-06 0,01589185 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 6,605E-06 7,946E-03 GO:0032862|activation of Rho GTPase activity, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 6,605E-06 5,297E-03 ! glycolysis GO:0006096 65 45 2,000 7,006E-06 4,214E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 9,903E-06 4,765E-03 GO:0046530|photoreceptor cell differentiation, ! negative regulation of platelet activation GO:0010544 9 6 1,000 9,903E-06 3,971E-03 GO:0010543|regulation of platelet activation, ! glucose catabolic process GO:0006007 82 55 2,000 1,288E-05 4,428E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,435E-05 4,316E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,847E-05 4,937E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,847E-05 4,443E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,847E-05 4,039E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 1,847E-05 3,702E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 1,000 1,847E-05 3,418E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 1,000 1,847E-05 3,174E-03 ! hexose catabolic process GO:0019320 104 67 2,000 2,337E-05 3,748E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,373E-05 3,568E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 2,965E-05 4,196E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,965E-05 3,963E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 2,965E-05 3,754E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,965E-05 3,567E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 2,965E-05 3,397E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 2,965E-05 3,242E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 2,965E-05 3,101E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 2,965E-05 2,972E-03 ! monosaccharide catabolic process GO:0046365 115 76 2,000 3,413E-05 3,284E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 3,622E-05 3,351E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! Golgi vesicle budding GO:0048194 22 11 1,000 3,622E-05 3,227E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 3,622E-05 3,112E-03 ! substrate-bound cell migration GO:0006929 13 11 1,000 3,622E-05 3,005E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 3,622E-05 2,905E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 3,622E-05 2,811E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 4,344E-05 3,266E-03 ! alcohol catabolic process GO:0046164 130 86 2,000 4,941E-05 3,602E-03 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 5,131E-05 3,631E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 5,131E-05 3,527E-03 ! regulation of cell adhesion GO:0030155 212 89 2,000 5,474E-05 3,658E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 5,983E-05 3,891E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 6,241E-05 3,951E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 7,882E-05 4,862E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 7,882E-05 4,741E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 8,928E-05 5,239E-03 ! membrane budding GO:0006900 37 17 1,000 8,928E-05 5,115E-03 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 8,928E-05 4,996E-03 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 1,004E-04 5,49E-03 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 1,121E-04 5,996E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,121E-04 5,866E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,121E-04 5,741E-03 ! visual learning GO:0008542 36 19 1,000 1,121E-04 5,621E-03 ! cell-cell junction organization GO:0045216 35 19 1,000 1,121E-04 5,507E-03 ! negative regulation of translation GO:0017148 29 20 1,000 1,245E-04 5,993E-03 ! negative regulation of coagulation GO:0050819 29 20 1,000 1,245E-04 5,875E-03 ! cell aging GO:0007569 44 21 1,000 1,376E-04 6,366E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,376E-04 6,246E-03 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,376E-04 6,13E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 1,000 1,513E-04 6,617E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 1,513E-04 6,499E-03 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,656E-04 6,989E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,656E-04 6,869E-03 ! visual behavior GO:0007632 42 23 1,000 1,656E-04 6,752E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,656E-04 6,64E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,805E-04 7,121E-03 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 1,805E-04 7,006E-03 ! regulation of behavior GO:0050795 43 24 1,000 1,805E-04 6,895E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,961E-04 7,374E-03 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,961E-04 7,26E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 2,124E-04 7,742E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,293E-04 8,233E-03 ! fat cell differentiation GO:0045444 50 27 1,000 2,293E-04 8,112E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,468E-04 8,605E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,468E-04 8,482E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 2,649E-04 8,977E-03 ! regulation of coagulation GO:0050818 46 29 1,000 2,649E-04 8,852E-03 ! eye morphogenesis GO:0048592 60 30 1,000 2,837E-04 9,35E-03 ! spindle organization GO:0007051 46 32 1,000 3,231E-04 0,01050645 ! protein targeting to membrane GO:0006612 68 33 1,000 3,438E-04 0,01102955 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 3,87E-04 0,01225312 ! cell junction organization GO:0034330 86 36 1,000 4,096E-04 0,01279889 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,096E-04 0,0126348 ! RNA export from nucleus GO:0006405 56 37 1,000 4,328E-04 0,01318101 ! meiosis I GO:0007127 65 37 1,000 4,328E-04 0,01301625 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 4,328E-04 0,01285556 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,566E-04 0,01339745 ! learning GO:0007612 77 39 1,000 4,81E-04 0,01394441 ! keratinocyte differentiation GO:0030216 62 41 1,000 5,318E-04 0,01523185 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 5,85E-04 0,01655943 ! striated muscle cell differentiation GO:0051146 82 43 1,000 5,85E-04 0,01636688 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 5,85E-04 0,01617875 ! cell growth GO:0016049 84 45 1,000 6,407E-04 0,01751812 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 6,695E-04 0,01809941 ! negative regulation of cell migration GO:0030336 115 46 1,000 6,695E-04 0,0178983 ! epidermal cell differentiation GO:0009913 68 46 1,000 6,695E-04 0,01770162 ! response to insulin stimulus GO:0032868 95 46 1,000 6,695E-04 0,01750921 ! response to calcium ion GO:0051592 81 47 1,000 6,989E-04 0,01808156 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,289E-04 0,01865751 ! vesicle organization GO:0016050 107 51 1,000 8,227E-04 0,02083515 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 8,882E-04 0,0222611 ! response to UV GO:0009411 104 53 1,000 8,882E-04 0,0220316 ! aging GO:0007568 103 55 1,000 9,562E-04 0,02347619 ! nuclear export GO:0051168 97 55 1,000 9,562E-04 0,02323905 ! negative regulation of cell motion GO:0051271 134 55 1,000 9,562E-04 0,02300666 ! regulation of DNA replication GO:0006275 101 56 1,000 9,911E-04 0,02361053 ! positive regulation of cell migration GO:0030335 126 57 1,000 1,027E-03 0,02421689 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 1,175E-03 0,02744207 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 1,252E-03 0,02897547 ! positive regulation of cell motion GO:0051272 146 64 1,000 1,292E-03 0,02961026 ! actin filament organization GO:0007015 148 66 1,000 1,374E-03 0,03117605 ! cell projection assembly GO:0030031 120 66 1,000 1,374E-03 0,03088469 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 1,415E-03 0,0315242 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,457E-03 0,03216516 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,5E-03 0,0328075 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,632E-03 0,03536828 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,632E-03 0,03505249 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,632E-03 0,03474229 ! learning or memory GO:0007611 147 73 1,000 1,677E-03 0,03538963 ! meiosis GO:0007126 121 74 1,000 1,723E-03 0,03603808 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,723E-03 0,03572741 ! eye development GO:0001654 143 74 1,000 1,723E-03 0,03542205 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 1,769E-03 0,03606578 ! meiotic cell cycle GO:0051321 122 75 1,000 1,769E-03 0,03576271 ! regulation of actin filament-based process GO:0032970 152 77 1,000 1,863E-03 0,03735651 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,863E-03 0,03704778 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 1,911E-03 0,03769192 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 1,96E-03 0,03833706 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,96E-03 0,03802789 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,96E-03 0,03772367 ! regulation of synaptic transmission GO:0050804 134 79 1,000 1,96E-03 0,03742427 ! response to metal ion GO:0010038 140 80 1,000 2,009E-03 0,0380623 ! muscle cell differentiation GO:0042692 159 80 1,000 2,009E-03 0,03776494 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 2,059E-03 0,03840135 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 2,059E-03 0,03810596 ! response to oxygen levels GO:0070482 176 83 1,000 2,16E-03 0,03967719 ! regulation of ligase activity GO:0051340 142 84 1,000 2,212E-03 0,04031653 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 2,212E-03 0,0400134 ! response to unfolded protein GO:0006986 131 85 1,000 2,264E-03 0,04065114 ! response to inorganic substance GO:0010035 153 86 1,000 2,317E-03 0,04128977 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,424E-03 0,04288258 ! regulation of neurological system process GO:0031644 148 88 1,000 2,424E-03 0,04256957 ! response to protein stimulus GO:0051789 149 91 1,000 2,589E-03 0,04513999 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,702E-03 0,04677048 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 2,702E-03 0,0464364 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 2,817E-03 0,04807369 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 2,817E-03 0,04773514 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 2,935E-03 0,04937888 ! interphase GO:0051325 213 98 1,000 2,994E-03 0,05003217 ! Golgi vesicle transport GO:0048193 207 99 1,000 3,055E-03 0,05068587 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 4,144E-03 0,0682887 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,144E-03 0,06782415 ! positive regulation of helicase activity GO:0051096 11 5 0,000 4,144E-03 0,06736588 ! neuron fate determination GO:0048664 7 5 0,000 4,144E-03 0,06691376 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,144E-03 0,06646767 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 4,144E-03 0,06602749 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 4,144E-03 0,06559309 ! polyol transport GO:0015791 12 5 0,000 4,144E-03 0,06516438 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 4,144E-03 0,06474124 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,144E-03 0,06432355 ! response to superoxide GO:0000303 10 5 0,000 4,144E-03 0,06391122 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,144E-03 0,06350414 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 4,144E-03 0,06310222 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 4,144E-03 0,06270535 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,144E-03 0,06231344 ! female meiosis GO:0007143 7 5 0,000 4,144E-03 0,0619264 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,144E-03 0,06154414 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,144E-03 0,06116657 ! cobalt ion transport GO:0006824 11 5 0,000 4,144E-03 0,0607936 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 4,144E-03 0,06042515 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 4,144E-03 0,06006115 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 4,144E-03 0,0597015 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,144E-03 0,05934613 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,144E-03 0,05899497 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 4,144E-03 0,05864794 ! embryonic camera-type eye development GO:0031076 10 5 0,000 4,144E-03 0,05830497 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,144E-03 0,05796599 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 4,144E-03 0,05763093 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 4,144E-03 0,05729971 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,144E-03 0,05697229 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,144E-03 0,05664858 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,144E-03 0,05632853 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 4,144E-03 0,05601208 ! negative chemotaxis GO:0050919 14 5 0,000 4,144E-03 0,05569916 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,144E-03 0,05538972 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,144E-03 0,0550837 ! sensory perception of bitter taste GO:0050913 7 5 0,000 4,144E-03 0,05478105 ! behavioral response to pain GO:0048266 9 5 0,000 4,144E-03 0,0544817 ! clathrin coat assembly GO:0048268 14 5 0,000 4,144E-03 0,0541856 ! Notch receptor processing GO:0007220 8 5 0,000 4,144E-03 0,0538927 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,144E-03 0,05360296 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,144E-03 0,05331631 ! micturition GO:0060073 9 5 0,000 4,144E-03 0,05303271 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,144E-03 0,05275212 ! copulation GO:0007620 9 5 0,000 4,144E-03 0,05247448 ! glial cell fate commitment GO:0021781 13 5 0,000 4,144E-03 0,05219974 ! protein maturation by protein folding GO:0022417 13 5 0,000 4,144E-03 0,05192787 ! spermidine metabolic process GO:0008216 7 5 0,000 4,144E-03 0,05165881 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,144E-03 0,05139253 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,144E-03 0,05112898 ! apoptotic cell clearance GO:0043277 20 5 0,000 4,144E-03 0,05086811 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,144E-03 0,0506099 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,144E-03 0,05035429 ! grooming behavior GO:0007625 6 5 0,000 4,144E-03 0,05010126 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,144E-03 0,04985075 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 4,144E-03 0,04960274 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,144E-03 0,04935718 ! response to protozoan GO:0001562 10 5 0,000 4,144E-03 0,04911404 ! positive regulation of glycolysis GO:0045821 14 5 0,000 4,144E-03 0,04887329 ! lymph vessel development GO:0001945 10 5 0,000 4,144E-03 0,04863488 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 4,144E-03 0,04839879 ! endochondral ossification GO:0001958 16 5 0,000 4,144E-03 0,04816498 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,144E-03 0,04793342 ! parathyroid gland development GO:0060017 13 5 0,000 4,144E-03 0,04770407 ! anagen GO:0042640 6 5 0,000 4,144E-03 0,04747691 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,144E-03 0,0472519 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,144E-03 0,04702901 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 4,144E-03 0,04680822 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 4,144E-03 0,04658949 ! dorsal spinal cord development GO:0021516 7 5 0,000 4,144E-03 0,04637279 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 4,144E-03 0,0461581 ! sphingoid catabolic process GO:0046521 6 5 0,000 4,144E-03 0,04594539 ! skeletal myofibril assembly GO:0014866 10 5 0,000 4,144E-03 0,04573463 ! smooth muscle tissue development GO:0048745 28 5 0,000 4,144E-03 0,0455258 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,144E-03 0,04531887 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,144E-03 0,0451138 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,144E-03 0,04491059 ! cardiac muscle fiber development GO:0048739 10 5 0,000 4,144E-03 0,04470919 ! transepithelial chloride transport GO:0030321 9 5 0,000 4,144E-03 0,0445096 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,144E-03 0,04431178 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 4,144E-03 0,04411571 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 4,144E-03 0,04392137 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,144E-03 0,04372873 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,144E-03 0,04353777 ! histidine catabolic process GO:0006548 6 5 0,000 4,144E-03 0,04334848 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 4,144E-03 0,04316082 ! microvillus organization GO:0032528 7 5 0,000 4,144E-03 0,04297479 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 4,144E-03 0,04279035 ! L-serine biosynthetic process GO:0006564 6 5 0,000 4,144E-03 0,04260748 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,144E-03 0,04242617 ! tryptophan metabolic process GO:0006568 9 5 0,000 4,144E-03 0,0422464 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 4,144E-03 0,04206815 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,144E-03 0,04189139 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 4,144E-03 0,04171611 ! polyol catabolic process GO:0046174 7 5 0,000 4,144E-03 0,04154229 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 4,144E-03 0,04136992 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,144E-03 0,04119897 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,144E-03 0,04102943 ! muscle cell migration GO:0014812 8 5 0,000 4,144E-03 0,04086127 ! mitochondrial fission GO:0000266 8 5 0,000 4,144E-03 0,04069449 ! sister chromatid cohesion GO:0007062 12 5 0,000 4,144E-03 0,04052907 ! mRNA transcription GO:0009299 9 5 0,000 4,144E-03 0,04036498 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 4,144E-03 0,04020222 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 4,144E-03 0,04004076 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 4,144E-03 0,0398806 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,144E-03 0,03972171 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,144E-03 0,03956409 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,144E-03 0,03940771 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,144E-03 0,03925256 ! response to food GO:0032094 6 5 0,000 4,144E-03 0,03909863 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,144E-03 0,0389459 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,144E-03 0,03879436 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 4,144E-03 0,03864399 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,144E-03 0,03849479 ! paraxial mesoderm development GO:0048339 14 5 0,000 4,144E-03 0,03834673 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 4,144E-03 0,03819981 ! forebrain neuron development GO:0021884 13 5 0,000 4,144E-03 0,03805401 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,144E-03 0,03790932 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 4,144E-03 0,03776572 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,144E-03 0,03762321 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,144E-03 0,03748177 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,144E-03 0,03734139 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 4,144E-03 0,03720205 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,144E-03 0,03706376 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 4,144E-03 0,03692648 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 4,144E-03 0,03679022 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,144E-03 0,03665496 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 4,144E-03 0,0365207 ! basic amino acid transport GO:0015802 11 5 0,000 4,144E-03 0,03638741 ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,144E-03 0,03625509 ! early endosome to late endosome transport GO:0045022 12 5 0,000 4,144E-03 0,03612373 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,144E-03 0,03599332 ! depyrimidination GO:0045008 10 5 0,000 4,144E-03 0,03586385 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,144E-03 0,03573531 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,144E-03 0,03560768 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,144E-03 0,03548096 ! zinc ion homeostasis GO:0055069 8 5 0,000 4,144E-03 0,03535514 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 4,144E-03 0,03523021 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 4,144E-03 0,03510616 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,144E-03 0,03498298 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,144E-03 0,03486067 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,144E-03 0,0347392 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 4,144E-03 0,03461858 ! peptidyl-arginine modification GO:0018195 9 5 0,000 4,144E-03 0,03449879 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,144E-03 0,03437983 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,144E-03 0,03426169 ! response to arsenic GO:0046685 10 5 0,000 4,144E-03 0,03414435 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 4,144E-03 0,03402782 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,144E-03 0,03391208 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 4,144E-03 0,03379712 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 4,144E-03 0,03368294 ! response to cadmium ion GO:0046686 7 5 0,000 4,144E-03 0,03356953 ! bile acid biosynthetic process GO:0006699 6 5 0,000 4,144E-03 0,03345688 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 4,144E-03 0,03334498 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,144E-03 0,03323383 ! decidualization GO:0046697 11 5 0,000 4,144E-03 0,03312342 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 4,144E-03 0,03301374 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 4,144E-03 0,03290479 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,144E-03 0,03279655 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,144E-03 0,03268902 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 4,144E-03 0,03258219 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,144E-03 0,03247606 ! neural tube patterning GO:0021532 7 5 0,000 4,144E-03 0,03237062 ! embryonic cleavage GO:0040016 6 5 0,000 4,144E-03 0,03226586 ! peroxisome fission GO:0016559 5 5 0,000 4,144E-03 0,03216178 ! histone demethylation GO:0016577 10 5 0,000 4,144E-03 0,03205836 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 4,144E-03 0,03195561 ! mitotic recombination GO:0006312 9 5 0,000 4,144E-03 0,03185352 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,144E-03 0,03175207 ! metaphase plate congression GO:0051310 7 5 0,000 4,144E-03 0,03165127 ! regulation of sterol transport GO:0032371 7 5 0,000 4,144E-03 0,03155111 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,144E-03 0,03145158 ! enteric nervous system development GO:0048484 8 5 0,000 4,144E-03 0,03135267 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 4,144E-03 0,03125439 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 4,144E-03 0,03115672 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 4,144E-03 0,03105966 ! muscle cell proliferation GO:0033002 11 5 0,000 4,144E-03 0,0309632 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,144E-03 0,03086734 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 4,144E-03 0,03077207 ! plasminogen activation GO:0031639 5 5 0,000 4,144E-03 0,03067739 ! B cell homeostasis GO:0001782 13 5 0,000 4,144E-03 0,03058328 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 4,144E-03 0,03048976 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,144E-03 0,0303968 ! metaphase GO:0051323 8 5 0,000 4,144E-03 0,03030441 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 4,144E-03 0,03021258 ! cellular response to nutrient GO:0031670 8 5 0,000 4,144E-03 0,0301213 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,144E-03 0,03003057 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,144E-03 0,02994039 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,144E-03 0,02985075 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 4,144E-03 0,02976164 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 4,144E-03 0,02967307 ! response to redox state GO:0051775 5 5 0,000 4,144E-03 0,02958502 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 4,144E-03 0,02949749 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 4,144E-03 0,02941047 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,144E-03 0,02932397 ! regulation of telomerase activity GO:0051972 6 5 0,000 4,144E-03 0,02923798 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,144E-03 0,02915249 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 4,144E-03 0,02906749 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,144E-03 0,028983 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 4,144E-03 0,02889899 ! striatum development GO:0021756 9 5 0,000 4,144E-03 0,02881546 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 4,144E-03 0,02873242 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,144E-03 0,02864986 ! glial cell migration GO:0008347 11 5 0,000 4,144E-03 0,02856777 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,144E-03 0,02848614 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 4,144E-03 0,02840499 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,144E-03 0,02832429 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,144E-03 0,02824405 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,144E-03 0,02816427 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,144E-03 0,02808493 ! neuroprotection GO:0043526 6 5 0,000 4,144E-03 0,02800604 ! neural plate development GO:0001840 8 5 0,000 4,144E-03 0,02792759 ! regulation of sensory perception GO:0051931 7 5 0,000 4,144E-03 0,02784958 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,144E-03 0,02777201 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,144E-03 0,02769486 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 4,144E-03 0,02761815 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 4,144E-03 0,02754185 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,144E-03 0,02746598 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,144E-03 0,02739052 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,144E-03 0,02731548 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,144E-03 0,02724085 ! spindle assembly GO:0051225 6 5 0,000 4,144E-03 0,02716662 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,144E-03 0,0270928 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,144E-03 0,02701938 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,144E-03 0,02694635 ! drug metabolic process GO:0017144 6 5 0,000 4,144E-03 0,02687372 ! stem cell division GO:0017145 11 5 0,000 4,144E-03 0,02680148 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,144E-03 0,02672963 ! organ regeneration GO:0031100 7 5 0,000 4,144E-03 0,02665816 ! carnitine metabolic process GO:0009437 7 5 0,000 4,144E-03 0,02658707 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 4,144E-03 0,02651636 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,144E-03 0,02644602 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,971E-03 0,03163866 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,971E-03 0,03155519 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 4,971E-03 0,03147215 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,971E-03 0,03138954 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,971E-03 0,03130737 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 4,971E-03 0,03122563 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 4,971E-03 0,03114431 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,971E-03 0,03106342 ! sleep GO:0030431 13 6 0,000 4,971E-03 0,03098294 ! response to oxygen radical GO:0000305 11 6 0,000 4,971E-03 0,03090288 ! positive regulation of axon extension GO:0045773 11 6 0,000 4,971E-03 0,03082324 ! myoblast cell fate commitment GO:0048625 16 6 0,000 4,971E-03 0,030744 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 4,971E-03 0,03066517 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 4,971E-03 0,03058674 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,971E-03 0,03050871 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,971E-03 0,03043108 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 4,971E-03 0,03035385 ! forebrain regionalization GO:0021871 8 6 0,000 4,971E-03 0,030277 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,971E-03 0,03020054 ! male meiosis GO:0007140 7 6 0,000 4,971E-03 0,03012447 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,971E-03 0,03004878 ! response to zinc ion GO:0010043 9 6 0,000 4,971E-03 0,02997347 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,971E-03 0,02989854 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 4,971E-03 0,02982398 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 4,971E-03 0,02974979 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,971E-03 0,02967597 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,971E-03 0,02960251 ! malate metabolic process GO:0006108 11 6 0,000 4,971E-03 0,02952942 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 4,971E-03 0,02945669 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 4,971E-03 0,02938431 ! protein refolding GO:0042026 15 6 0,000 4,971E-03 0,02931229 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,971E-03 0,02924062 ! opsonization GO:0008228 8 6 0,000 4,971E-03 0,02916931 ! mating behavior GO:0007617 7 6 0,000 4,971E-03 0,02909833 ! neuron remodeling GO:0016322 15 6 0,000 4,971E-03 0,02902771 ! erythrocyte maturation GO:0043249 7 6 0,000 4,971E-03 0,02895742 ! embryonic hemopoiesis GO:0035162 14 6 0,000 4,971E-03 0,02888748 ! equilibrioception GO:0050957 14 6 0,000 4,971E-03 0,02881787 ! protein amino acid dealkylation GO:0008214 12 6 0,000 4,971E-03 0,02874859 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 4,971E-03 0,02867965 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 4,971E-03 0,02861104 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,971E-03 0,02854276 ! response to interferon-gamma GO:0034341 15 6 0,000 4,971E-03 0,0284748 ! toxin metabolic process GO:0009404 11 6 0,000 4,971E-03 0,02840716 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,971E-03 0,02833985 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,971E-03 0,02827285 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 4,971E-03 0,02820617 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 4,971E-03 0,0281398 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 4,971E-03 0,02807374 ! cGMP-mediated signaling GO:0019934 13 6 0,000 4,971E-03 0,028008 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,971E-03 0,02794256 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 4,971E-03 0,02787743 ! thymic T cell selection GO:0045061 12 6 0,000 4,971E-03 0,02781259 ! protein lipoylation GO:0009249 10 6 0,000 4,971E-03 0,02774806 ! cysteine metabolic process GO:0006534 10 6 0,000 4,971E-03 0,02768383 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,971E-03 0,0276199 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,971E-03 0,02755626 ! glutamate catabolic process GO:0006538 10 6 0,000 4,971E-03 0,02749291 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 4,971E-03 0,02742985 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,971E-03 0,02736708 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 4,971E-03 0,0273046 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 4,971E-03 0,0272424 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,971E-03 0,02718049 ! hyperosmotic response GO:0006972 9 6 0,000 4,971E-03 0,02711886 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 4,971E-03 0,0270575 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 4,971E-03 0,02699642 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,971E-03 0,02693562 ! urea metabolic process GO:0019627 7 6 0,000 4,971E-03 0,02687509 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,971E-03 0,02681483 ! neutrophil activation GO:0042119 8 6 0,000 4,971E-03 0,02675484 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,971E-03 0,02669512 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 4,971E-03 0,02663567 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,971E-03 0,02657648 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,971E-03 0,02651755 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,971E-03 0,02645888 ! neuron apoptosis GO:0051402 9 6 0,000 4,971E-03 0,02640048 ! nucleoside salvage GO:0043174 9 6 0,000 4,971E-03 0,02634232 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 4,971E-03 0,02628443 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,971E-03 0,02622679 ! T cell mediated immunity GO:0002456 16 6 0,000 4,971E-03 0,0261694 ! male sex determination GO:0030238 15 6 0,000 4,971E-03 0,02611226 ! carnitine transport GO:0015879 10 6 0,000 4,971E-03 0,02605537 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 4,971E-03 0,02599873 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,971E-03 0,02594233 ! positive regulation of exocytosis GO:0045921 8 6 0,000 4,971E-03 0,02588618 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 4,971E-03 0,02583027 ! 5S class rRNA transcription GO:0042791 11 6 0,000 4,971E-03 0,0257746 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,971E-03 0,02571917 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 4,971E-03 0,02566398 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 4,971E-03 0,02560903 ! sodium ion homeostasis GO:0055078 11 6 0,000 4,971E-03 0,02555431 ! establishment of spindle localization GO:0051293 12 6 0,000 4,971E-03 0,02549982 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 4,971E-03 0,02544556 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,971E-03 0,02539154 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 4,971E-03 0,02533774 ! neural nucleus development GO:0048857 14 6 0,000 4,971E-03 0,02528418 ! response to UV-C GO:0010225 11 6 0,000 4,971E-03 0,02523083 ! astrocyte development GO:0014002 15 6 0,000 4,971E-03 0,02517772 ! protein targeting to lysosome GO:0006622 10 6 0,000 4,971E-03 0,02512482 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,971E-03 0,02507215 ! interaction with symbiont GO:0051702 13 6 0,000 4,971E-03 0,0250197 ! regulation of dendrite development GO:0050773 16 6 0,000 4,971E-03 0,02496746 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,971E-03 0,02491545 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 4,971E-03 0,02486365 ! response to copper ion GO:0046688 10 6 0,000 4,971E-03 0,02481207 ! response to exogenous dsRNA GO:0043330 10 6 0,000 4,971E-03 0,02476069 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 4,971E-03 0,02470954 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,971E-03 0,02465859 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,971E-03 0,02460785 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,971E-03 0,02455732 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 4,971E-03 0,024507 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,971E-03 0,02445688 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,971E-03 0,02440697 ! hair follicle maturation GO:0048820 7 6 0,000 4,971E-03 0,02435726 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,971E-03 0,02430775 ! Schwann cell development GO:0014044 15 6 0,000 4,971E-03 0,02425845 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 4,971E-03 0,02420934 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,971E-03 0,02416044 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 4,971E-03 0,02411172 ! subpallium development GO:0021544 10 6 0,000 4,971E-03 0,02406321 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 4,971E-03 0,02401489 ! histone ubiquitination GO:0016574 8 6 0,000 4,971E-03 0,02396676 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 4,971E-03 0,02391883 ! maintenance of organ identity GO:0048496 9 6 0,000 4,971E-03 0,02387109 ! G2 phase GO:0051319 16 6 0,000 4,971E-03 0,02382354 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 4,971E-03 0,02377617 ! establishment of planar polarity GO:0001736 7 6 0,000 4,971E-03 0,023729 ! regulation of mast cell activation GO:0033003 12 6 0,000 4,971E-03 0,02368201 ! membrane to membrane docking GO:0022614 14 6 0,000 4,971E-03 0,02363521 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,971E-03 0,02358859 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 4,971E-03 0,02354216 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,971E-03 0,0234959 ! receptor internalization GO:0031623 10 6 0,000 4,971E-03 0,02344983 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 4,971E-03 0,02340394 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 4,971E-03 0,02335823 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,971E-03 0,0233127 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 4,971E-03 0,02326735 ! protein deubiquitination GO:0016579 14 6 0,000 4,971E-03 0,02322217 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 4,971E-03 0,02317716 ! protein destabilization GO:0031648 9 6 0,000 4,971E-03 0,02313233 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,971E-03 0,02308767 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 4,971E-03 0,02304319 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,971E-03 0,02299888 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 4,971E-03 0,02295473 ! progesterone metabolic process GO:0042448 10 6 0,000 4,971E-03 0,02291076 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 4,971E-03 0,02286695 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 4,971E-03 0,02282331 ! negative regulation of axon extension GO:0030517 21 6 0,000 4,971E-03 0,02277984 ! removal of superoxide radicals GO:0019430 11 6 0,000 4,971E-03 0,02273653 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,971E-03 0,02269339 ! determination of adult lifespan GO:0008340 15 6 0,000 4,971E-03 0,02265041 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 4,971E-03 0,02260759 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 4,971E-03 0,02256493 ! cerebellar cortex formation GO:0021697 8 6 0,000 4,971E-03 0,02252244 ! catecholamine transport GO:0051937 9 6 0,000 4,971E-03 0,0224801 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 4,971E-03 0,02243793 ! sensory cilium assembly GO:0035058 10 6 0,000 4,971E-03 0,02239591 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,971E-03 0,02235405 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 4,971E-03 0,02231234 ! maternal placenta development GO:0001893 12 6 0,000 4,971E-03 0,02227079 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 4,971E-03 0,0222294 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,971E-03 0,02218815 ! negative regulation of B cell activation GO:0050869 13 6 0,000 4,971E-03 0,02214707 ! protein amino acid prenylation GO:0018346 16 6 0,000 4,971E-03 0,02210613 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,971E-03 0,02206534 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 4,971E-03 0,02202471 ! positive regulation of coagulation GO:0050820 12 6 0,000 4,971E-03 0,02198422 ! tRNA transcription GO:0009304 14 7 0,000 5,797E-03 0,025591 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 5,797E-03 0,02554413 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 5,797E-03 0,02549743 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,797E-03 0,0254509 ! regulation of helicase activity GO:0051095 15 7 0,000 5,797E-03 0,02540454 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 5,797E-03 0,02535835 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 5,797E-03 0,02531233 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,797E-03 0,02526648 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 5,797E-03 0,02522079 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,797E-03 0,02517526 ! prostate gland development GO:0030850 13 7 0,000 5,797E-03 0,0251299 ! nucleotide-sugar transport GO:0015780 12 7 0,000 5,797E-03 0,0250847 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,797E-03 0,02503967 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,797E-03 0,02499479 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 5,797E-03 0,02495008 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,797E-03 0,02490553 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 5,797E-03 0,02486113 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 5,797E-03 0,02481689 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 5,797E-03 0,02477281 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 5,797E-03 0,02472889 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,797E-03 0,02468512 ! SMAD protein complex assembly GO:0007183 12 7 0,000 5,797E-03 0,02464151 ! glycolipid transport GO:0046836 10 7 0,000 5,797E-03 0,02459805 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,797E-03 0,02455474 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,797E-03 0,02451159 ! neuron adhesion GO:0007158 12 7 0,000 5,797E-03 0,02446859 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 5,797E-03 0,02442574 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,797E-03 0,02438303 ! actin-myosin filament sliding GO:0033275 11 7 0,000 5,797E-03 0,02434048 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 5,797E-03 0,02429807 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 5,797E-03 0,02425582 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 5,797E-03 0,02421371 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 5,797E-03 0,02417174 ! mRNA stabilization GO:0048255 18 7 0,000 5,797E-03 0,02412992 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 5,797E-03 0,02408825 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 5,797E-03 0,02404672 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 5,797E-03 0,02400533 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 5,797E-03 0,02396408 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,797E-03 0,02392298 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,797E-03 0,02388201 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,797E-03 0,02384119 ! lipoprotein transport GO:0042953 14 7 0,000 5,797E-03 0,0238005 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,797E-03 0,02375996 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,797E-03 0,02371955 ! rhythmic behavior GO:0007622 15 7 0,000 5,797E-03 0,02367928 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 5,797E-03 0,02363914 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 5,797E-03 0,02359915 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 5,797E-03 0,02355928 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,797E-03 0,02351955 ! regulation of odontogenesis GO:0042481 13 7 0,000 5,797E-03 0,02347996 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,797E-03 0,0234405 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 5,797E-03 0,02340117 ! mechanosensory behavior GO:0007638 14 7 0,000 5,797E-03 0,02336197 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 5,797E-03 0,0233229 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,797E-03 0,02328396 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 5,797E-03 0,02324516 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,797E-03 0,02320648 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,797E-03 0,02316793 ! spinal cord patterning GO:0021511 13 7 0,000 5,797E-03 0,02312951 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 5,797E-03 0,02309122 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,797E-03 0,02305305 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 5,797E-03 0,02301501 ! adrenal gland development GO:0030325 17 7 0,000 5,797E-03 0,02297709 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 5,797E-03 0,0229393 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 5,797E-03 0,02290163 ! ovulation GO:0030728 9 7 0,000 5,797E-03 0,02286409 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 5,797E-03 0,02282667 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,797E-03 0,02278937 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 5,797E-03 0,02275219 ! microtubule nucleation GO:0007020 20 7 0,000 5,797E-03 0,02271514 ! proline biosynthetic process GO:0006561 10 7 0,000 5,797E-03 0,0226782 ! thyroid hormone generation GO:0006590 13 7 0,000 5,797E-03 0,02264139 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 5,797E-03 0,02260469 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 5,797E-03 0,02256811 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 5,797E-03 0,02253166 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,797E-03 0,02249531 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,797E-03 0,02245909 ! galactose metabolic process GO:0006012 13 7 0,000 5,797E-03 0,02242298 ! vesicle fusion GO:0006906 17 7 0,000 5,797E-03 0,02238699 ! response to dietary excess GO:0002021 8 7 0,000 5,797E-03 0,02235111 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,797E-03 0,02231535 ! intracellular pH reduction GO:0051452 11 7 0,000 5,797E-03 0,0222797 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,797E-03 0,02224417 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 5,797E-03 0,02220875 ! organ growth GO:0035265 15 7 0,000 5,797E-03 0,02217344 ! purine salvage GO:0043101 10 7 0,000 5,797E-03 0,02213825 ! nucleoside transport GO:0015858 8 7 0,000 5,797E-03 0,02210316 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 5,797E-03 0,02206819 ! parturition GO:0007567 14 7 0,000 5,797E-03 0,02203333 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 5,797E-03 0,02199857 ! rRNA modification GO:0000154 14 7 0,000 5,797E-03 0,02196393 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 5,797E-03 0,02192939 ! spindle checkpoint GO:0031577 15 7 0,000 5,797E-03 0,02189497 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 5,797E-03 0,02186065 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 5,797E-03 0,02182644 ! macrophage differentiation GO:0030225 11 7 0,000 5,797E-03 0,02179234 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,797E-03 0,02175834 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,797E-03 0,02172445 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 5,797E-03 0,02169066 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,797E-03 0,02165698 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 5,797E-03 0,0216234 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,797E-03 0,02158993 ! fibrinolysis GO:0042730 10 7 0,000 5,797E-03 0,02155656 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 5,797E-03 0,02152329 ! eating behavior GO:0042755 7 7 0,000 5,797E-03 0,02149013 ! B cell lineage commitment GO:0002326 21 7 0,000 5,797E-03 0,02145707 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,797E-03 0,02142411 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 5,797E-03 0,02139125 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 5,797E-03 0,02135849 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,797E-03 0,02132583 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 5,797E-03 0,02129327 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,797E-03 0,02126082 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 5,797E-03 0,02122845 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 5,797E-03 0,02119619 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 5,797E-03 0,02116403 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 5,797E-03 0,02113196 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,797E-03 0,02109999 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 5,797E-03 0,02106812 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,797E-03 0,02103634 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,797E-03 0,02100466 ! regulation of meiosis GO:0040020 12 7 0,000 5,797E-03 0,02097307 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 5,797E-03 0,02094158 ! T cell lineage commitment GO:0002360 16 7 0,000 5,797E-03 0,02091019 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 5,797E-03 0,02087888 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,797E-03 0,02084768 ! oxygen homeostasis GO:0032364 12 7 0,000 5,797E-03 0,02081656 ! transcription termination GO:0006353 13 7 0,000 5,797E-03 0,02078554 ! response to tumor cell GO:0002347 13 7 0,000 5,797E-03 0,02075461 ! regulation of respiratory burst GO:0060263 11 7 0,000 5,797E-03 0,02072377 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,797E-03 0,02069302 ! anaphase GO:0051322 17 7 0,000 5,797E-03 0,02066236 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 5,797E-03 0,0206318 ! axonal fasciculation GO:0007413 18 7 0,000 5,797E-03 0,02060132 ! negative regulation of nuclear division GO:0051784 14 7 0,000 5,797E-03 0,02057094 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 5,797E-03 0,02054064 ! peptidyl-threonine modification GO:0018210 25 7 0,000 5,797E-03 0,02051043 ! diuresis GO:0030146 12 7 0,000 5,797E-03 0,02048032 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,797E-03 0,02045029 ! thiamin metabolic process GO:0006772 7 7 0,000 5,797E-03 0,02042034 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,797E-03 0,02039049 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 5,797E-03 0,02036072 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 5,797E-03 0,02033104 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,797E-03 0,02030145 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,797E-03 0,02027194 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,797E-03 0,02024252 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,797E-03 0,02021318 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 5,797E-03 0,02018393 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,797E-03 0,02015476 ! glycolipid catabolic process GO:0019377 15 7 0,000 5,797E-03 0,02012568 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,797E-03 0,02009668 ! lymph node development GO:0048535 10 7 0,000 5,797E-03 0,02006776 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 5,797E-03 0,02003893 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,797E-03 0,02001018 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 5,797E-03 0,01998151 ! endosome to lysosome transport GO:0008333 11 7 0,000 5,797E-03 0,01995293 ! protein modification by small protein removal GO:0070646 16 7 0,000 5,797E-03 0,01992442 ! adult feeding behavior GO:0008343 9 7 0,000 5,797E-03 0,019896 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 5,797E-03 0,01986766 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 5,797E-03 0,0198394 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,797E-03 0,01981121 ! muscle adaptation GO:0043500 14 7 0,000 5,797E-03 0,01978311 ! embryonic heart tube development GO:0035050 10 7 0,000 5,797E-03 0,01975509 ! retina homeostasis GO:0001895 12 7 0,000 5,797E-03 0,01972715 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 5,797E-03 0,01969929 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 5,797E-03 0,0196715 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 5,797E-03 0,0196438 ! protein prenylation GO:0018342 18 7 0,000 5,797E-03 0,01961617 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 5,797E-03 0,01958862 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 5,797E-03 0,01956114 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,797E-03 0,01953375 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,622E-03 0,02228418 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,622E-03 0,02225306 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,622E-03 0,02222202 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,622E-03 0,02219107 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,622E-03 0,02216021 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,622E-03 0,02212943 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,622E-03 0,02209874 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,622E-03 0,02206813 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,622E-03 0,02203761 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,622E-03 0,02200717 ! meiotic prophase I GO:0007128 13 8 0,000 6,622E-03 0,02197681 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,622E-03 0,02194654 ! oligopeptide transport GO:0006857 15 8 0,000 6,622E-03 0,02191635 ! UTP metabolic process GO:0046051 8 8 0,000 6,622E-03 0,02188625 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,622E-03 0,02185623 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,622E-03 0,02182629 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,622E-03 0,02179643 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,622E-03 0,02176665 ! succinate metabolic process GO:0006105 14 8 0,000 6,622E-03 0,02173696 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,622E-03 0,02170734 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,622E-03 0,02167781 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,622E-03 0,02164836 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,622E-03 0,02161898 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,622E-03 0,02158969 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,622E-03 0,02156047 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,622E-03 0,02153134 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,622E-03 0,02150228 ! reflex GO:0060004 16 8 0,000 6,622E-03 0,0214733 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,622E-03 0,0214444 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,622E-03 0,02141558 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,622E-03 0,02138683 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,622E-03 0,02135816 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,622E-03 0,02132957 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,622E-03 0,02130106 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,622E-03 0,02127262 ! pigment granule organization GO:0048753 16 8 0,000 6,622E-03 0,02124425 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,622E-03 0,02121597 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,622E-03 0,02118775 ! astrocyte differentiation GO:0048708 18 8 0,000 6,622E-03 0,02115961 ! histidine metabolic process GO:0006547 16 8 0,000 6,622E-03 0,02113155 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,622E-03 0,02110356 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,622E-03 0,02107565 ! glycine catabolic process GO:0006546 13 8 0,000 6,622E-03 0,02104781 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,622E-03 0,02102004 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,622E-03 0,02099234 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,622E-03 0,02096472 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,622E-03 0,02093717 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,622E-03 0,0209097 ! melanin metabolic process GO:0006582 15 8 0,000 6,622E-03 0,02088229 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,622E-03 0,02085496 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,622E-03 0,0208277 ! macrophage activation GO:0042116 12 8 0,000 6,622E-03 0,02080051 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,622E-03 0,02077339 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,622E-03 0,02074634 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,622E-03 0,02071936 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,622E-03 0,02069245 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,622E-03 0,02066562 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,622E-03 0,02063885 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,622E-03 0,02061215 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,622E-03 0,02058552 ! osteoblast development GO:0002076 16 8 0,000 6,622E-03 0,02055895 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,622E-03 0,02053246 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,622E-03 0,02050604 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,622E-03 0,02047968 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,622E-03 0,02045339 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,622E-03 0,02042717 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,622E-03 0,02040101 ! response to UV-B GO:0010224 16 8 0,000 6,622E-03 0,02037492 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,622E-03 0,0203489 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,622E-03 0,02032295 ! intermediate filament organization GO:0045109 12 8 0,000 6,622E-03 0,02029706 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,622E-03 0,02027123 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,622E-03 0,02024548 ! cellular extravasation GO:0045123 12 8 0,000 6,622E-03 0,02021978 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,622E-03 0,02019416 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,622E-03 0,02016859 ! response to antibiotic GO:0046677 11 8 0,000 6,622E-03 0,0201431 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,622E-03 0,02011766 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,622E-03 0,02009229 ! DNA topological change GO:0006265 12 8 0,000 6,622E-03 0,02006699 ! response to tropane GO:0014073 15 8 0,000 6,622E-03 0,02004175 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,622E-03 0,02001657 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,622E-03 0,01999146 ! melanosome transport GO:0032402 13 8 0,000 6,622E-03 0,0199664 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,622E-03 0,01994141 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,622E-03 0,01991649 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,622E-03 0,01989162 ! mast cell activation GO:0045576 14 8 0,000 6,622E-03 0,01986682 ! multicellular organismal aging GO:0010259 18 8 0,000 6,622E-03 0,01984208 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,622E-03 0,0198174 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,622E-03 0,01979278 ! nucleosome disassembly GO:0006337 14 8 0,000 6,622E-03 0,01976823 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,622E-03 0,01974373 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,622E-03 0,01971929 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,622E-03 0,01969492 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,622E-03 0,0196706 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,622E-03 0,01964635 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,622E-03 0,01962215 ! intracellular lipid transport GO:0032365 13 8 0,000 6,622E-03 0,01959802 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,622E-03 0,01957394 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,622E-03 0,01954993 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,622E-03 0,01952597 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,622E-03 0,01950207 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,622E-03 0,01947823 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,622E-03 0,01945444 ! hormone catabolic process GO:0042447 17 8 0,000 6,622E-03 0,01943072 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,622E-03 0,01940705 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,622E-03 0,01938344 ! ATP catabolic process GO:0006200 11 8 0,000 6,622E-03 0,01935989 ! blastocyst growth GO:0001832 19 8 0,000 6,622E-03 0,0193364 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,622E-03 0,01931296 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,622E-03 0,01928958 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,622E-03 0,01926625 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,622E-03 0,01924298 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,622E-03 0,01921977 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,622E-03 0,01919661 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,622E-03 0,01917351 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,622E-03 0,01915047 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,622E-03 0,01912748 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,622E-03 0,01910454 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,622E-03 0,01908166 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,622E-03 0,01905884 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,622E-03 0,01903607 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,622E-03 0,01901335 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,622E-03 0,01899069 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,622E-03 0,01896808 ! regulation of developmental growth GO:0048638 15 9 0,000 7,447E-03 0,02130523 ! axon extension GO:0048675 15 9 0,000 7,447E-03 0,02127993 ! autophagic vacuole formation GO:0000045 15 9 0,000 7,447E-03 0,02125469 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,447E-03 0,0212295 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 7,447E-03 0,02120438 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 7,447E-03 0,02117932 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,447E-03 0,02115431 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 7,447E-03 0,02112937 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 7,447E-03 0,02110448 ! cell proliferation in forebrain GO:0021846 15 9 0,000 7,447E-03 0,02107965 ! phosphate transport GO:0006817 19 9 0,000 7,447E-03 0,02105488 ! reproductive behavior GO:0019098 19 9 0,000 7,447E-03 0,02103017 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,447E-03 0,02100551 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 7,447E-03 0,02098092 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,447E-03 0,02095638 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 7,447E-03 0,02093189 ! GTP metabolic process GO:0046039 9 9 0,000 7,447E-03 0,02090747 ! RNA methylation GO:0001510 15 9 0,000 7,447E-03 0,0208831 ! elastic fiber assembly GO:0048251 15 9 0,000 7,447E-03 0,02085879 ! induction of positive chemotaxis GO:0050930 15 9 0,000 7,447E-03 0,02083454 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 7,447E-03 0,02081034 ! artery development GO:0060840 24 9 0,000 7,447E-03 0,0207862 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 7,447E-03 0,02076211 ! regulation of glycolysis GO:0006110 21 9 0,000 7,447E-03 0,02073808 ! cerebral cortex cell migration GO:0021795 15 9 0,000 7,447E-03 0,02071411 ! keratinocyte proliferation GO:0043616 14 9 0,000 7,447E-03 0,02069019 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 7,447E-03 0,02066632 ! chemosensory behavior GO:0007635 20 9 0,000 7,447E-03 0,02064251 ! microtubule bundle formation GO:0001578 21 9 0,000 7,447E-03 0,02061876 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,447E-03 0,02059506 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 7,447E-03 0,02057141 ! leukocyte degranulation GO:0043299 16 9 0,000 7,447E-03 0,02054782 ! bile acid and bile salt transport GO:0015721 13 9 0,000 7,447E-03 0,02052429 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 7,447E-03 0,0205008 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 7,447E-03 0,02047737 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,447E-03 0,020454 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,447E-03 0,02043067 ! protein targeting to ER GO:0045047 22 9 0,000 7,447E-03 0,02040741 ! ceramide biosynthetic process GO:0046513 19 9 0,000 7,447E-03 0,02038419 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 7,447E-03 0,02036102 ! T cell selection GO:0045058 23 9 0,000 7,447E-03 0,02033791 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 7,447E-03 0,02031485 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 7,447E-03 0,02029185 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,447E-03 0,02026889 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 7,447E-03 0,02024599 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,447E-03 0,02022314 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,447E-03 0,02020034 ! mannose metabolic process GO:0006013 13 9 0,000 7,447E-03 0,02017759 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 7,447E-03 0,0201549 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 7,447E-03 0,02013225 ! Rac protein signal transduction GO:0016601 17 9 0,000 7,447E-03 0,02010965 ! receptor clustering GO:0043113 18 9 0,000 7,447E-03 0,02008711 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 7,447E-03 0,02006462 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,447E-03 0,02004217 ! ruffle organization GO:0031529 15 9 0,000 7,447E-03 0,02001978 ! retinol metabolic process GO:0042572 18 9 0,000 7,447E-03 0,01999744 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 7,447E-03 0,01997514 ! behavioral fear response GO:0001662 22 9 0,000 7,447E-03 0,0199529 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 7,447E-03 0,0199307 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 7,447E-03 0,01990856 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 7,447E-03 0,01988646 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 7,447E-03 0,01986441 ! protein heterooligomerization GO:0051291 16 9 0,000 7,447E-03 0,01984242 ! oligodendrocyte development GO:0014003 10 9 0,000 7,447E-03 0,01982047 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 7,447E-03 0,01979857 ! segment specification GO:0007379 13 9 0,000 7,447E-03 0,01977671 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,447E-03 0,01975491 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 7,447E-03 0,01973315 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,447E-03 0,01971144 ! response to amine stimulus GO:0014075 13 9 0,000 7,447E-03 0,01968978 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,447E-03 0,01966817 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 7,447E-03 0,0196466 ! erythrocyte development GO:0048821 15 9 0,000 7,447E-03 0,01962508 ! gas homeostasis GO:0033483 16 9 0,000 7,447E-03 0,01960361 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,447E-03 0,01958219 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 7,447E-03 0,01956081 ! renal water homeostasis GO:0003091 14 9 0,000 7,447E-03 0,01953948 ! postreplication repair GO:0006301 22 9 0,000 7,447E-03 0,01951819 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 7,447E-03 0,01949696 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 7,447E-03 0,01947576 ! icosanoid secretion GO:0032309 15 9 0,000 7,447E-03 0,01945462 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 7,447E-03 0,01943352 ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,447E-03 0,01941246 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 7,447E-03 0,01939145 ! regulation of cell division GO:0051302 15 9 0,000 7,447E-03 0,01937049 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 7,447E-03 0,01934957 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 7,447E-03 0,0193287 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,447E-03 0,01930787 ! sterol catabolic process GO:0016127 11 9 0,000 7,447E-03 0,01928708 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,447E-03 0,01926635 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 7,447E-03 0,01924565 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 7,447E-03 0,019225 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 7,447E-03 0,0192044 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 7,447E-03 0,01918383 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 7,447E-03 0,01916332 ! musculoskeletal movement GO:0050881 14 9 0,000 7,447E-03 0,01914284 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 7,447E-03 0,01912241 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 7,447E-03 0,01910203 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,447E-03 0,01908168 ! purine base metabolic process GO:0006144 21 9 0,000 7,447E-03 0,01906138 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 7,447E-03 0,01904113 ! pigment granule transport GO:0051904 17 9 0,000 7,447E-03 0,01902091 ! regulation of fibrinolysis GO:0051917 16 9 0,000 7,447E-03 0,01900074 ! regulation of telomere maintenance GO:0032204 14 9 0,000 7,447E-03 0,01898062 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 7,447E-03 0,01896053 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,447E-03 0,01894049 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,447E-03 0,01892049 ! mitochondrion localization GO:0051646 15 9 0,000 7,447E-03 0,01890053 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 8,271E-03 0,02097011 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 8,271E-03 0,02094803 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,271E-03 0,02092601 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 8,271E-03 0,02090403 ! synapsis GO:0007129 13 10 0,000 8,271E-03 0,02088209 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 8,271E-03 0,0208602 ! N-glycan processing GO:0006491 20 10 0,000 8,271E-03 0,02083836 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 8,271E-03 0,02081656 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 8,271E-03 0,02079481 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 8,271E-03 0,0207731 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 8,271E-03 0,02075144 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 8,271E-03 0,02072982 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 8,271E-03 0,02070825 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 8,271E-03 0,02068673 ! androgen metabolic process GO:0008209 17 10 0,000 8,271E-03 0,02066525 ! phospholipid efflux GO:0033700 16 10 0,000 8,271E-03 0,02064381 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,271E-03 0,02062242 ! positive regulation of heart contraction GO:0045823 16 10 0,000 8,271E-03 0,02060107 ! lung alveolus development GO:0048286 26 10 0,000 8,271E-03 0,02057976 ! pathogenesis GO:0009405 13 10 0,000 8,271E-03 0,0205585 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,271E-03 0,02053729 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 8,271E-03 0,02051612 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 8,271E-03 0,02049499 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 8,271E-03 0,0204739 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 8,271E-03 0,02045286 ! endoderm development GO:0007492 16 10 0,000 8,271E-03 0,02043186 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 8,271E-03 0,0204109 ! arginine catabolic process GO:0006527 13 10 0,000 8,271E-03 0,02038999 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,271E-03 0,02036912 ! proline metabolic process GO:0006560 13 10 0,000 8,271E-03 0,02034829 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,271E-03 0,02032751 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 8,271E-03 0,02030677 ! polyamine biosynthetic process GO:0006596 12 10 0,000 8,271E-03 0,02028607 ! V(D)J recombination GO:0033151 28 10 0,000 8,271E-03 0,02026541 ! reverse cholesterol transport GO:0043691 16 10 0,000 8,271E-03 0,02024479 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 8,271E-03 0,02022422 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 8,271E-03 0,02020369 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 8,271E-03 0,0201832 ! regulation of sodium ion transport GO:0002028 21 10 0,000 8,271E-03 0,02016275 ! multicellular organism growth GO:0035264 18 10 0,000 8,271E-03 0,02014234 ! phagocytosis, engulfment GO:0006911 28 10 0,000 8,271E-03 0,02012197 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 8,271E-03 0,02010165 ! epithelial cell development GO:0002064 20 10 0,000 8,271E-03 0,02008136 ! lens development in camera-type eye GO:0002088 16 10 0,000 8,271E-03 0,02006112 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,271E-03 0,02004092 ! macroautophagy GO:0016236 17 10 0,000 8,271E-03 0,02002076 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 8,271E-03 0,02000063 ! positive regulation of translational initiation GO:0045948 11 10 0,000 8,271E-03 0,01998055 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 8,271E-03 0,01996051 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 8,271E-03 0,01994051 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 8,271E-03 0,01992055 ! copper ion homeostasis GO:0055070 13 10 0,000 8,271E-03 0,01990063 ! regulation of bone resorption GO:0045124 25 10 0,000 8,271E-03 0,01988075 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,271E-03 0,01986091 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,271E-03 0,01984111 ! alpha-beta T cell activation GO:0046631 23 10 0,000 8,271E-03 0,01982135 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 8,271E-03 0,01980162 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 8,271E-03 0,01978194 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 8,271E-03 0,0197623 ! blastoderm segmentation GO:0007350 18 10 0,000 8,271E-03 0,01974269 ! response to dsRNA GO:0043331 20 10 0,000 8,271E-03 0,01972312 ! DNA ligation GO:0006266 19 10 0,000 8,271E-03 0,0197036 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 8,271E-03 0,01968411 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,271E-03 0,01966466 ! melanosome localization GO:0032400 16 10 0,000 8,271E-03 0,01964524 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 8,271E-03 0,01962587 ! regulation of B cell differentiation GO:0045577 19 10 0,000 8,271E-03 0,01960653 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 8,271E-03 0,01958724 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,271E-03 0,01956798 ! mRNA cleavage GO:0006379 17 10 0,000 8,271E-03 0,01954875 ! protein sumoylation GO:0016925 15 10 0,000 8,271E-03 0,01952957 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,271E-03 0,01951042 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,271E-03 0,01949131 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,271E-03 0,01947224 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 8,271E-03 0,01945321 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 8,271E-03 0,01943421 ! salivary gland development GO:0007431 27 10 0,000 8,271E-03 0,01941525 ! prophase GO:0051324 15 10 0,000 8,271E-03 0,01939633 ! negative regulation of neurological system process GO:0031645 19 10 0,000 8,271E-03 0,01937744 ! apical protein localization GO:0045176 15 10 0,000 8,271E-03 0,01935859 ! ubiquinone metabolic process GO:0006743 15 10 0,000 8,271E-03 0,01933978 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 8,271E-03 0,019321 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 8,271E-03 0,01930226 ! midbrain development GO:0030901 13 10 0,000 8,271E-03 0,01928356 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 8,271E-03 0,01926489 ! methionine biosynthetic process GO:0009086 19 10 0,000 8,271E-03 0,01924626 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 8,271E-03 0,01922766 ! quaternary ammonium group transport GO:0015697 21 10 0,000 8,271E-03 0,0192091 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,271E-03 0,01919058 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,271E-03 0,01917209 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 8,271E-03 0,01915364 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 8,271E-03 0,01913522 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 8,271E-03 0,01911684 ! oocyte development GO:0048599 17 10 0,000 8,271E-03 0,0190985 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,271E-03 0,01908018 ! blastocyst formation GO:0001825 17 10 0,000 8,271E-03 0,01906191 ! cerebellar cortex development GO:0021695 15 10 0,000 8,271E-03 0,01904367 ! activation of innate immune response GO:0002218 12 10 0,000 8,271E-03 0,01902546 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 8,271E-03 0,01900729 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 8,271E-03 0,01898915 ! response to nicotine GO:0035094 20 10 0,000 8,271E-03 0,01897105 ! negative regulation of immune effector process GO:0002698 20 10 0,000 8,271E-03 0,01895298 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,271E-03 0,01893495 ! localization within membrane GO:0051668 20 10 0,000 8,271E-03 0,01891695 ! negative regulation of muscle development GO:0048635 20 11 0,000 9,095E-03 0,02078061 ! respiratory burst GO:0045730 17 11 0,000 9,095E-03 0,02076089 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 9,095E-03 0,02074121 ! neuron fate specification GO:0048665 17 11 0,000 9,095E-03 0,02072157 ! telencephalon cell migration GO:0022029 20 11 0,000 9,095E-03 0,02070197 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 9,095E-03 0,0206824 ! thyroid gland development GO:0030878 26 11 0,000 9,095E-03 0,02066287 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 9,095E-03 0,02064338 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 9,095E-03 0,02062392 ! response to pain GO:0048265 24 11 0,000 9,095E-03 0,0206045 ! detection of mechanical stimulus GO:0050982 22 11 0,000 9,095E-03 0,02058512 ! T cell proliferation GO:0042098 26 11 0,000 9,095E-03 0,02056577 ! blood vessel remodeling GO:0001974 29 11 0,000 9,095E-03 0,02054646 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 9,095E-03 0,02052719 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 9,095E-03 0,02050795 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 9,095E-03 0,02048875 ! ventral spinal cord development GO:0021517 21 11 0,000 9,095E-03 0,02046958 ! negative regulation of proteolysis GO:0045861 25 11 0,000 9,095E-03 0,02045045 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 9,095E-03 0,02043135 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 9,095E-03 0,0204123 ! melanocyte differentiation GO:0030318 21 11 0,000 9,095E-03 0,02039327 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 9,095E-03 0,02037428 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 9,095E-03 0,02035533 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 9,095E-03 0,02033641 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 9,095E-03 0,02031753 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 9,095E-03 0,02029868 ! lipid digestion GO:0044241 18 11 0,000 9,095E-03 0,02027987 ! UV protection GO:0009650 19 11 0,000 9,095E-03 0,02026109 ! adult heart development GO:0007512 14 11 0,000 9,095E-03 0,02024235 ! chondrocyte differentiation GO:0002062 24 11 0,000 9,095E-03 0,02022364 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 9,095E-03 0,02020497 ! temperature homeostasis GO:0001659 17 11 0,000 9,095E-03 0,02018633 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 9,095E-03 0,02016772 ! negative regulation of ossification GO:0030279 26 11 0,000 9,095E-03 0,02014915 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 9,095E-03 0,02013062 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 9,095E-03 0,02011212 ! regulation of organ growth GO:0046620 13 11 0,000 9,095E-03 0,02009365 ! pigment granule localization GO:0051875 20 11 0,000 9,095E-03 0,02007521 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 9,095E-03 0,02005681 ! vasoconstriction GO:0042310 18 11 0,000 9,095E-03 0,02003844 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 9,095E-03 0,02002011 ! embryonic axis specification GO:0000578 18 11 0,000 9,095E-03 0,02000181 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 9,095E-03 0,01998354 ! snRNA metabolic process GO:0016073 24 11 0,000 9,095E-03 0,01996531 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 9,095E-03 0,01994711 ! nitric oxide metabolic process GO:0046209 15 11 0,000 9,095E-03 0,01992894 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 9,095E-03 0,01991081 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 9,095E-03 0,01989271 ! zymogen activation GO:0031638 15 11 0,000 9,095E-03 0,01987464 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 9,095E-03 0,01985661 ! neuroblast proliferation GO:0007405 24 11 0,000 9,095E-03 0,0198386 ! nucleosome positioning GO:0016584 15 11 0,000 9,095E-03 0,01982064 ! regulation of isotype switching GO:0045191 22 11 0,000 9,095E-03 0,0198027 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 9,095E-03 0,01978479 ! glutathione biosynthetic process GO:0006750 13 11 0,000 9,095E-03 0,01976692 ! regulation of leukocyte migration GO:0002685 26 11 0,000 9,095E-03 0,01974908 ! acid secretion GO:0046717 18 11 0,000 9,095E-03 0,01973127 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 9,095E-03 0,0197135 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 9,095E-03 0,01969575 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 9,095E-03 0,01967804 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 9,095E-03 0,01966036 ! oocyte differentiation GO:0009994 18 11 0,000 9,095E-03 0,01964271 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 9,095E-03 0,0196251 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 9,095E-03 0,01960751 ! cholesterol efflux GO:0033344 19 11 0,000 9,095E-03 0,01958996 ! anterior/posterior axis specification GO:0009948 18 11 0,000 9,095E-03 0,01957243 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 9,095E-03 0,01955494 ! negative regulation of glucose import GO:0046325 17 11 0,000 9,095E-03 0,01953748 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 9,095E-03 0,01952005 ! embryonic gut development GO:0048566 15 11 0,000 9,095E-03 0,01950266 ! regulation of organic acid transport GO:0032890 18 11 0,000 9,095E-03 0,01948529 ! cardiac cell differentiation GO:0035051 31 11 0,000 9,095E-03 0,01946795 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 9,095E-03 0,01945065 ! defense response to fungus GO:0050832 13 11 0,000 9,095E-03 0,01943338 ! developmental induction GO:0031128 19 11 0,000 9,095E-03 0,01941613 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 9,095E-03 0,01939892 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 9,095E-03 0,01938174 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 9,095E-03 0,01936459 ! sequestering of metal ion GO:0051238 14 11 0,000 9,095E-03 0,01934746 ! lamellipodium assembly GO:0030032 20 11 0,000 9,095E-03 0,01933037 ! nucleus localization GO:0051647 19 11 0,000 9,095E-03 0,01931331 ! regulation of synapse organization GO:0050807 17 11 0,000 9,095E-03 0,01929628 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 9,918E-03 0,02102357 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 9,918E-03 0,02100506 ! positive regulation of blood pressure GO:0045777 17 12 0,000 9,918E-03 0,02098659 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 9,918E-03 0,02096815 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 9,918E-03 0,02094974 ! virus-host interaction GO:0019048 29 12 0,000 9,918E-03 0,02093136 ! regulation of B cell proliferation GO:0030888 20 12 0,000 9,918E-03 0,02091302 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 9,918E-03 0,0208947 ! cartilage condensation GO:0001502 20 12 0,000 9,918E-03 0,02087642 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 9,918E-03 0,02085817 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,918E-03 0,02083996 ! protein complex disassembly GO:0043241 27 12 0,000 9,918E-03 0,02082177 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,918E-03 0,02080362 ! regulation of cell projection assembly GO:0060491 30 12 0,000 9,918E-03 0,0207855 ! hippocampus development GO:0021766 26 12 0,000 9,918E-03 0,02076741 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 9,918E-03 0,02074935 ! cytokine biosynthetic process GO:0042089 21 12 0,000 9,918E-03 0,02073132 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,918E-03 0,02071333 ! positive regulation of cell growth GO:0030307 22 12 0,000 9,918E-03 0,02069536 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 9,918E-03 0,02067743 ! regulation of exit from mitosis GO:0007096 17 12 0,000 9,918E-03 0,02065952 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 9,918E-03 0,02064165 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 9,918E-03 0,02062381 ! drug transport GO:0015893 16 12 0,000 9,918E-03 0,020606 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 9,918E-03 0,02058822 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 9,918E-03 0,02057047 ! tyrosine metabolic process GO:0006570 16 12 0,000 9,918E-03 0,02055276 ! polyamine metabolic process GO:0006595 17 12 0,000 9,918E-03 0,02053507 ! focal adhesion formation GO:0048041 35 12 0,000 9,918E-03 0,02051741 ! mitotic spindle organization GO:0007052 21 12 0,000 9,918E-03 0,02049979 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 9,918E-03 0,02048219 ! forebrain cell migration GO:0021885 21 12 0,000 9,918E-03 0,02046462 ! asymmetric protein localization GO:0008105 20 12 0,000 9,918E-03 0,02044709 ! membrane protein proteolysis GO:0033619 25 12 0,000 9,918E-03 0,02042958 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 9,918E-03 0,02041211 ! entry into host cell GO:0030260 32 12 0,000 9,918E-03 0,02039466 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 9,918E-03 0,02037724 ! monoamine transport GO:0015844 18 12 0,000 9,918E-03 0,02035986 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,918E-03 0,0203425 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 9,918E-03 0,02032517 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 9,918E-03 0,02030787 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 9,918E-03 0,0202906 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,918E-03 0,02027337 ! protein targeting to peroxisome GO:0006625 23 12 0,000 9,918E-03 0,02025616 ! protein homotetramerization GO:0051289 21 12 0,000 9,918E-03 0,02023897 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 9,918E-03 0,02022182 ! regulation of phagocytosis GO:0050764 16 12 0,000 9,918E-03 0,0202047 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,918E-03 0,02018761 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 9,918E-03 0,02017054 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 9,918E-03 0,02015351 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,918E-03 0,0201365 ! cranial nerve development GO:0021545 20 12 0,000 9,918E-03 0,02011952 ! fucose catabolic process GO:0019317 22 12 0,000 9,918E-03 0,02010257 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 9,918E-03 0,02008565 ! histone acetylation GO:0016573 26 12 0,000 9,918E-03 0,02006876 ! histone methylation GO:0016571 26 12 0,000 9,918E-03 0,02005189 ! mRNA polyadenylation GO:0006378 23 12 0,000 9,918E-03 0,02003506 ! autonomic nervous system development GO:0048483 24 12 0,000 9,918E-03 0,02001825 ! gland morphogenesis GO:0022612 29 12 0,000 9,918E-03 0,02000147 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 9,918E-03 0,01998472 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,918E-03 0,01996799 ! T cell homeostasis GO:0043029 25 12 0,000 9,918E-03 0,0199513 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 9,918E-03 0,01993463 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 9,918E-03 0,01991799 ! spleen development GO:0048536 22 12 0,000 9,918E-03 0,01990138 ! digestive tract morphogenesis GO:0048546 26 12 0,000 9,918E-03 0,01988479 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 9,918E-03 0,01986824 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 9,918E-03 0,01985171 ! regulation of RNA splicing GO:0043484 20 12 0,000 9,918E-03 0,0198352 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 9,918E-03 0,01981873 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 9,918E-03 0,01980228 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 9,918E-03 0,01978586 ! response to cold GO:0009409 17 12 0,000 9,918E-03 0,01976947 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 9,918E-03 0,01975311 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 9,918E-03 0,01973677 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01073979 0,02135532 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01073979 0,02133769 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01073979 0,02132008 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01073979 0,02130251 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01073979 0,02128496 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01073979 0,02126744 ! lipid localization GO:0010876 28 13 0,000 0,01073979 0,02124995 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01073979 0,02123249 ! organelle fusion GO:0048284 32 13 0,000 0,01073979 0,02121506 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01073979 0,02119766 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01073979 0,02118028 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01073979 0,02116293 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01073979 0,02114562 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01073979 0,02112833 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01073979 0,02111106 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01073979 0,02109383 ! methionine metabolic process GO:0006555 27 13 0,000 0,01073979 0,02107663 ! plasma membrane organization GO:0007009 24 13 0,000 0,01073979 0,02105945 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01073979 0,0210423 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01073979 0,02102518 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01073979 0,02100808 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01073979 0,02099102 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01073979 0,02097398 ! response to X-ray GO:0010165 25 13 0,000 0,01073979 0,02095697 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01073979 0,02093999 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01073979 0,02092303 ! exocrine system development GO:0035272 32 13 0,000 0,01073979 0,0209061 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01073979 0,0208892 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01073979 0,02087233 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01073979 0,02085548 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01073979 0,02083866 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01073979 0,02082187 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01073979 0,02080511 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01073979 0,02078837 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01073979 0,02077166 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01073979 0,02075497 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01073979 0,02073832 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01073979 0,02072169 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01073979 0,02070508 ! ribosome assembly GO:0042255 17 13 0,000 0,01073979 0,0206885 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01073979 0,02067195 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01073979 0,02065543 ! chromatin silencing GO:0006342 26 13 0,000 0,01073979 0,02063893 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01073979 0,02062246 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01073979 0,02060601 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01073979 0,0205896 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01073979 0,0205732 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01073979 0,02055684 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01073979 0,02054049 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01073979 0,02052418 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01073979 0,02050789 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01073979 0,02049163 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01073979 0,02047539 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01073979 0,02045918 ! embryonic placenta development GO:0001892 23 13 0,000 0,01073979 0,02044299 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01073979 0,02042683 ! insulin secretion GO:0030073 23 13 0,000 0,01073979 0,0204107 ! actin filament polymerization GO:0030041 24 13 0,000 0,01073979 0,02039459 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01073979 0,0203785 ! acrosome reaction GO:0007340 18 13 0,000 0,01073979 0,02036244 ! rRNA transcription GO:0009303 25 14 0,000 0,01156133 0,0219028 ! lactation GO:0007595 26 14 0,000 0,01156133 0,02188557 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01156133 0,02186836 ! reproductive cellular process GO:0048610 20 14 0,000 0,01156133 0,02185118 ! tRNA modification GO:0006400 20 14 0,000 0,01156133 0,02183403 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01156133 0,02181691 ! regulation of S phase GO:0033261 23 14 0,000 0,01156133 0,02179981 ! water transport GO:0006833 21 14 0,000 0,01156133 0,02178274 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01156133 0,02176569 ! non-recombinational repair GO:0000726 25 14 0,000 0,01156133 0,02174868 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01156133 0,02173169 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01156133 0,02171472 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01156133 0,02169778 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01156133 0,02168087 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01156133 0,02166399 ! palate development GO:0060021 31 14 0,000 0,01156133 0,02164713 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01156133 0,02163029 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01156133 0,02161349 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01156133 0,02159671 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01156133 0,02157995 ! arginine metabolic process GO:0006525 17 14 0,000 0,01156133 0,02156322 ! regulation of heart rate GO:0002027 24 14 0,000 0,01156133 0,02154652 ! organic alcohol transport GO:0015850 29 14 0,000 0,01156133 0,02152984 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01156133 0,02151319 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01156133 0,02149657 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01156133 0,02147997 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01156133 0,02146339 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01156133 0,02144684 ! L-amino acid transport GO:0015807 30 14 0,000 0,01156133 0,02143032 ! bone mineralization GO:0030282 17 14 0,000 0,01156133 0,02141382 ! stem cell development GO:0048864 43 14 0,000 0,01156133 0,02139735 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01156133 0,0213809 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01156133 0,02136448 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01156133 0,02134809 ! cerebellum development GO:0021549 21 14 0,000 0,01156133 0,02133172 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01156133 0,02131537 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01156133 0,02129905 ! response to gamma radiation GO:0010332 28 14 0,000 0,01156133 0,02128275 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01156133 0,02126648 ! cofactor transport GO:0051181 26 14 0,000 0,01156133 0,02125023 ! NADP metabolic process GO:0006739 24 14 0,000 0,01156133 0,02123401 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01156133 0,02121782 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01156133 0,02120164 ! intestinal absorption GO:0050892 25 14 0,000 0,01156133 0,0211855 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01156133 0,02116937 ! oxygen transport GO:0015671 21 14 0,000 0,01156133 0,02115328 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01156133 0,0211372 ! male genitalia development GO:0030539 24 14 0,000 0,01156133 0,02112115 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01156133 0,02110513 ! regulation of axon extension GO:0030516 37 14 0,000 0,01156133 0,02108913 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01156133 0,02107315 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01156133 0,0210572 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01238221 0,02253525 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01238221 0,02251821 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01238221 0,02250121 ! superoxide anion generation GO:0042554 20 15 0,000 0,01238221 0,02248422 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01238221 0,02246727 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01238221 0,02245034 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01238221 0,02243343 ! copper ion transport GO:0006825 20 15 0,000 0,01238221 0,02241655 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01238221 0,0223997 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01238221 0,02238287 ! sulfate transport GO:0008272 23 15 0,000 0,01238221 0,02236606 ! response to cAMP GO:0051591 22 15 0,000 0,01238221 0,02234928 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01238221 0,02233253 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01238221 0,0223158 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01238221 0,0222991 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01238221 0,02228242 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01238221 0,02226577 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01238221 0,02224914 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01238221 0,02223253 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01238221 0,02221595 ! pituitary gland development GO:0021983 29 15 0,000 0,01238221 0,0221994 ! vesicle coating GO:0006901 33 15 0,000 0,01238221 0,02218287 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01238221 0,02216637 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01238221 0,02214989 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01238221 0,02213343 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01238221 0,022117 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01238221 0,02210059 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01238221 0,02208421 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01238221 0,02206785 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01238221 0,02205151 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01238221 0,0220352 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01238221 0,02201892 ! histone deacetylation GO:0016575 20 15 0,000 0,01238221 0,02200266 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01238221 0,02198642 ! tissue regeneration GO:0042246 26 15 0,000 0,01238221 0,0219702 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01238221 0,02195401 ! water homeostasis GO:0030104 27 15 0,000 0,01238221 0,02193785 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01238221 0,0219217 ! muscle maintenance GO:0046716 26 15 0,000 0,01238221 0,02190558 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01238221 0,02188949 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01238221 0,02187342 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01238221 0,02185737 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01238221 0,02184135 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01238221 0,02182534 ! cell killing GO:0001906 29 15 0,000 0,01238221 0,02180937 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01238221 0,02179341 ! detection of bacterium GO:0016045 18 15 0,000 0,01238221 0,02177748 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01238221 0,02176157 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01238221 0,02174569 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01238221 0,02172983 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01238221 0,02171399 ! peptide hormone processing GO:0016486 23 15 0,000 0,01238221 0,02169818 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01320244 0,02311867 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01320244 0,02310186 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01320244 0,02308507 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01320244 0,02306831 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01320244 0,02305157 ! bone remodeling GO:0046849 27 16 0,000 0,01320244 0,02303485 ! filopodium assembly GO:0046847 32 16 0,000 0,01320244 0,02301816 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01320244 0,02300149 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01320244 0,02298485 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01320244 0,02296823 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01320244 0,02295163 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01320244 0,02293506 ! startle response GO:0001964 28 16 0,000 0,01320244 0,02291851 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01320244 0,02290199 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01320244 0,02288549 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01320244 0,02286901 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01320244 0,02285256 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01320244 0,02283613 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01320244 0,02281973 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01320244 0,02280334 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01320244 0,02278699 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01320244 0,02277065 ! response to osmotic stress GO:0006970 25 16 0,000 0,01320244 0,02275434 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01320244 0,02273805 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01320244 0,02272179 ! fructose metabolic process GO:0006000 25 16 0,000 0,01320244 0,02270555 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01320244 0,02268933 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01320244 0,02267313 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01320244 0,02265696 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01320244 0,02264081 ! axon cargo transport GO:0008088 43 16 0,000 0,01320244 0,02262469 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01320244 0,02260858 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01320244 0,0225925 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01320244 0,02257645 ! DNA replication initiation GO:0006270 27 16 0,000 0,01320244 0,02256041 ! neuron recognition GO:0008038 35 16 0,000 0,01320244 0,0225444 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01320244 0,02252841 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01320244 0,02251244 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01320244 0,0224965 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01320244 0,02248058 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01320244 0,02246468 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01320244 0,02244881 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01320244 0,02243295 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01320244 0,02241712 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01320244 0,02240131 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01320244 0,02238552 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01320244 0,02236976 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01320244 0,02235402 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01320244 0,0223383 ! defense response to virus GO:0051607 37 16 0,000 0,01320244 0,0223226 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01402201 0,02369168 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01402201 0,02367505 ! metencephalon development GO:0022037 30 17 0,000 0,01402201 0,02365845 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01402201 0,02364187 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01402201 0,02362532 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01402201 0,02360878 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01402201 0,02359227 ! signal complex assembly GO:0007172 41 17 0,000 0,01402201 0,02357579 ! endothelial cell migration GO:0043542 28 17 0,000 0,01402201 0,02355932 ! inositol metabolic process GO:0006020 28 17 0,000 0,01402201 0,02354288 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01402201 0,02352646 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01402201 0,02351007 ! glial cell development GO:0021782 27 17 0,000 0,01402201 0,0234937 ! limbic system development GO:0021761 36 17 0,000 0,01402201 0,02347735 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01402201 0,02346102 ! adult walking behavior GO:0007628 33 17 0,000 0,01402201 0,02344472 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01402201 0,02342844 ! heart looping GO:0001947 30 17 0,000 0,01402201 0,02341218 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01402201 0,02339594 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01402201 0,02337973 ! myoblast differentiation GO:0045445 45 17 0,000 0,01402201 0,02336354 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01402201 0,02334737 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01402201 0,02333122 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01402201 0,0233151 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01402201 0,023299 ! glycine metabolic process GO:0006544 28 17 0,000 0,01402201 0,02328292 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01402201 0,02326686 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01402201 0,02325083 ! NAD metabolic process GO:0019674 29 17 0,000 0,01402201 0,02323481 ! DNA integration GO:0015074 29 17 0,000 0,01402201 0,02321882 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01402201 0,02320285 ! regulation of protein binding GO:0043393 33 17 0,000 0,01402201 0,02318691 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01402201 0,02317098 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01402201 0,02315508 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01402201 0,0231392 ! genitalia development GO:0048806 30 17 0,000 0,01402201 0,02312334 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01402201 0,0231075 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01402201 0,02309168 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01402201 0,02307589 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01402201 0,02306012 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01402201 0,02304436 ! steroid catabolic process GO:0006706 31 17 0,000 0,01402201 0,02302863 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01402201 0,02301293 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01402201 0,02299724 ! gas transport GO:0015669 25 17 0,000 0,01402201 0,02298157 ! organic cation transport GO:0015695 31 17 0,000 0,01402201 0,02296593 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01402201 0,02295031 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01402201 0,0229347 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01402201 0,02291912 ! microspike assembly GO:0030035 36 17 0,000 0,01402201 0,02290356 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01402201 0,02288803 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01402201 0,02287251 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01484093 0,02419192 ! neuron maturation GO:0042551 42 18 0,000 0,01484093 0,02417554 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01484093 0,02415918 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01484093 0,02414285 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01484093 0,02412653 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01484093 0,02411024 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01484093 0,02409397 ! memory GO:0007613 31 18 0,000 0,01484093 0,02407773 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01484093 0,0240615 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01484093 0,0240453 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01484093 0,02402912 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01484093 0,02401296 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01484093 0,02399682 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01484093 0,0239807 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01484093 0,02396461 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01484093 0,02394854 ! response to retinoic acid GO:0032526 26 18 0,000 0,01484093 0,02393249 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01484093 0,02391646 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01484093 0,02390045 ! response to fungus GO:0009620 21 18 0,000 0,01484093 0,02388446 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01484093 0,02386849 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01484093 0,02385255 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01484093 0,02383663 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01484093 0,02382073 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01484093 0,02380485 ! vitamin transport GO:0051180 27 18 0,000 0,01484093 0,02378899 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01484093 0,02377315 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01484093 0,02375733 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01484093 0,02374153 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01484093 0,02372576 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01484093 0,02371001 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01484093 0,02369427 ! nerve development GO:0021675 28 18 0,000 0,01484093 0,02367856 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01484093 0,02366287 ! protein secretion GO:0009306 39 19 0,000 0,01565919 0,024951 ! positive regulation of translation GO:0045727 30 19 0,000 0,01565919 0,02493449 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01565919 0,024918 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01565919 0,02490153 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01565919 0,02488508 ! skin development GO:0043588 36 19 0,000 0,01565919 0,02486866 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01565919 0,02485225 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01565919 0,02483587 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01565919 0,02481951 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01565919 0,02480317 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01565919 0,02478685 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01565919 0,02477056 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01565919 0,02475428 ! cerebral cortex development GO:0021987 36 19 0,000 0,01565919 0,02473803 ! pigmentation during development GO:0048066 41 19 0,000 0,01565919 0,02472179 ! response to vitamin A GO:0033189 27 19 0,000 0,01565919 0,02470558 ! heme metabolic process GO:0042168 36 19 0,000 0,01565919 0,02468939 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01565919 0,02467323 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01565919 0,02465708 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01565919 0,02464095 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01565919 0,02462485 ! peptide cross-linking GO:0018149 37 19 0,000 0,01565919 0,02460876 ! protein export from nucleus GO:0006611 36 19 0,000 0,01565919 0,0245927 ! heart process GO:0003015 30 19 0,000 0,01565919 0,02457666 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01565919 0,02456064 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01565919 0,02454464 ! cellular pigmentation GO:0033059 36 19 0,000 0,01565919 0,02452866 ! G1 phase GO:0051318 40 19 0,000 0,01565919 0,0245127 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01565919 0,02449676 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01565919 0,02448084 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01565919 0,02446494 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01565919 0,02444907 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01565919 0,02443321 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01565919 0,02441738 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01565919 0,02440156 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01565919 0,02438577 ! cilium assembly GO:0042384 37 19 0,000 0,01565919 0,02437 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01565919 0,02435424 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0164768 0,0256093 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0164768 0,02559276 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0164768 0,02557625 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0164768 0,02555976 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0164768 0,02554329 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,0164768 0,02552685 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0164768 0,02551042 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0164768 0,02549401 ! response to vitamin GO:0033273 31 20 0,000 0,0164768 0,02547763 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0164768 0,02546127 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0164768 0,02544492 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0164768 0,0254286 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0164768 0,0254123 ! response to alkaloid GO:0043279 38 20 0,000 0,0164768 0,02539602 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0164768 0,02537976 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0164768 0,02536353 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,0164768 0,02534731 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0164768 0,02533111 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0164768 0,02531494 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0164768 0,02529878 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0164768 0,02528265 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0164768 0,02526653 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0164768 0,02525044 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0164768 0,02523437 ! body fluid secretion GO:0007589 31 20 0,000 0,0164768 0,02521832 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0164768 0,02520228 ! peptide secretion GO:0002790 35 20 0,000 0,0164768 0,02518627 ! stem cell differentiation GO:0048863 53 20 0,000 0,0164768 0,02517028 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0164768 0,02515431 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0164768 0,02513836 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0164768 0,02512243 ! sensory perception of pain GO:0019233 30 20 0,000 0,0164768 0,02510652 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0164768 0,02509063 ! diencephalon development GO:0021536 34 20 0,000 0,0164768 0,02507476 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0164768 0,02505891 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0164768 0,02504308 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0164768 0,02502727 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0164768 0,02501148 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0164768 0,02499571 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0164768 0,02497996 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0164768 0,02496423 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0164768 0,02494852 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0164768 0,02493283 ! regulation of glucose import GO:0046324 29 20 0,000 0,0164768 0,02491715 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0164768 0,0249015 ! actin filament-based movement GO:0030048 43 20 0,000 0,0164768 0,02488587 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0164768 0,02487026 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0164768 0,02485467 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0164768 0,02483909 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0164768 0,02482354 ! regulation of cell killing GO:0031341 42 21 0,000 0,01729377 0,02603805 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01729377 0,02602176 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01729377 0,0260055 ! hormone secretion GO:0046879 38 21 0,000 0,01729377 0,02598926 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01729377 0,02597303 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01729377 0,02595683 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01729377 0,02594065 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01729377 0,02592449 ! axis specification GO:0009798 38 21 0,000 0,01729377 0,02590834 ! ovarian follicle development GO:0001541 35 21 0,000 0,01729377 0,02589222 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01729377 0,02587612 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01729377 0,02586004 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01729377 0,02584398 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01729377 0,02582793 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01729377 0,02581191 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01729377 0,02579591 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01729377 0,02577993 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01729377 0,02576396 ! cytolysis GO:0019835 24 21 0,000 0,01729377 0,02574802 ! vasodilation GO:0042311 39 21 0,000 0,01729377 0,0257321 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01729377 0,02571619 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01729377 0,02570031 ! oogenesis GO:0048477 36 21 0,000 0,01729377 0,02568444 ! DNA modification GO:0006304 34 21 0,000 0,01729377 0,0256686 ! collagen fibril organization GO:0030199 59 21 0,000 0,01729377 0,02565277 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01729377 0,02563697 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01729377 0,02562118 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01729377 0,02560542 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01729377 0,02558967 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01729377 0,02557394 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01729377 0,02555823 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01729377 0,02554254 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01729377 0,02552687 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01729377 0,02551122 ! collagen catabolic process GO:0030574 28 21 0,000 0,01729377 0,02549559 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01729377 0,02547998 ! gut development GO:0048565 39 21 0,000 0,01729377 0,02546438 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01811008 0,02665006 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01811008 0,02663377 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01811008 0,0266175 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01811008 0,02660125 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01811008 0,02658502 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01811008 0,02656881 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01811008 0,02655262 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01811008 0,02653644 ! regeneration GO:0031099 41 22 0,000 0,01811008 0,02652029 ! keratinization GO:0031424 28 22 0,000 0,01811008 0,02650416 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01811008 0,02648805 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01811008 0,02647196 ! sensory perception of taste GO:0050909 28 22 0,000 0,01811008 0,02645588 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01811008 0,02643983 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01811008 0,0264238 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01811008 0,02640778 ! vacuolar transport GO:0007034 36 22 0,000 0,01811008 0,02639179 ! lysosome organization GO:0007040 41 22 0,000 0,01811008 0,02637581 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01811008 0,02635986 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01811008 0,02634392 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01811008 0,026328 ! fucose metabolic process GO:0006004 39 22 0,000 0,01811008 0,0263121 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01811008 0,02629622 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01811008 0,02628036 ! ureteric bud development GO:0001657 43 22 0,000 0,01811008 0,02626452 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01811008 0,0262487 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01811008 0,0262329 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01811008 0,02621711 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01811008 0,02620135 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01811008 0,0261856 ! sarcomere organization GO:0045214 30 22 0,000 0,01811008 0,02616988 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01811008 0,02615417 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01811008 0,02613848 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01811008 0,02612281 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01811008 0,02610716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01811008 0,02609152 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01811008 0,02607591 ! protein stabilization GO:0050821 39 22 0,000 0,01811008 0,02606031 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01892573 0,02721776 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01892573 0,0272015 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01892573 0,02718526 ! gluconeogenesis GO:0006094 33 23 0,000 0,01892573 0,02716904 ! viral genome replication GO:0019079 41 23 0,000 0,01892573 0,02715284 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01892573 0,02713666 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01892573 0,0271205 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01892573 0,02710436 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01892573 0,02708823 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01892573 0,02707213 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01892573 0,02705604 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01892573 0,02703997 ! response to ethanol GO:0045471 46 23 0,000 0,01892573 0,02702393 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01892573 0,0270079 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01892573 0,02699189 ! peroxisome organization GO:0007031 37 23 0,000 0,01892573 0,0269759 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01892573 0,02695993 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01892573 0,02694397 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01892573 0,02692804 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01892573 0,02691213 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01892573 0,02689623 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01892573 0,02688035 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01892573 0,02686449 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01892573 0,02684865 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01892573 0,02683283 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01892573 0,02681703 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01892573 0,02680125 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01892573 0,02678548 ! fatty acid transport GO:0015908 44 23 0,000 0,01892573 0,02676973 ! platelet activation GO:0030168 37 23 0,000 0,01892573 0,02675401 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01892573 0,0267383 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01892573 0,0267226 ! hormone transport GO:0009914 40 23 0,000 0,01892573 0,02670693 ! cell-cell recognition GO:0009988 25 23 0,000 0,01892573 0,02669128 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01892573 0,02667564 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01892573 0,02666002 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01892573 0,02664442 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01892573 0,02662884 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01892573 0,02661328 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01974074 0,02774312 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01974074 0,02772693 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01974074 0,02771075 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01974074 0,02769459 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01974074 0,02767845 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01974074 0,02766233 ! vesicle docking GO:0048278 47 24 0,000 0,01974074 0,02764623 ! spinal cord development GO:0021510 47 24 0,000 0,01974074 0,02763015 ! vacuole organization GO:0007033 43 24 0,000 0,01974074 0,02761409 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01974074 0,02759804 ! digestive system process GO:0022600 39 24 0,000 0,01974074 0,02758201 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01974074 0,027566 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01974074 0,02755002 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01974074 0,02753404 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01974074 0,02751809 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01974074 0,02750216 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01974074 0,02748624 ! membrane depolarization GO:0051899 39 24 0,000 0,01974074 0,02747034 ! pallium development GO:0021543 49 24 0,000 0,01974074 0,02745447 ! pentose metabolic process GO:0019321 35 24 0,000 0,01974074 0,02743861 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01974074 0,02742276 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01974074 0,02740694 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01974074 0,02739113 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01974074 0,02737535 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01974074 0,02735958 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01974074 0,02734383 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01974074 0,02732809 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01974074 0,02731238 ! regulation of amine transport GO:0051952 40 24 0,000 0,01974074 0,02729668 ! protein tetramerization GO:0051262 52 24 0,000 0,01974074 0,027281 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0205551 0,02839011 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,0205551 0,02837382 ! myelination GO:0042552 45 25 0,000 0,0205551 0,02835755 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0205551 0,0283413 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0205551 0,02832507 ! phototransduction GO:0007602 33 25 0,000 0,0205551 0,02830886 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0205551 0,02829266 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,0205551 0,02827648 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,0205551 0,02826033 ! sperm motility GO:0030317 31 25 0,000 0,0205551 0,02824419 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0205551 0,02822807 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0205551 0,02821196 ! receptor metabolic process GO:0043112 46 25 0,000 0,0205551 0,02819588 ! chromosome condensation GO:0030261 45 25 0,000 0,0205551 0,02817981 ! response to starvation GO:0042594 42 25 0,000 0,0205551 0,02816377 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0205551 0,02814774 ! neural crest cell development GO:0014032 54 25 0,000 0,0205551 0,02813172 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0205551 0,02811573 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0205551 0,02809976 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0205551 0,0280838 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0205551 0,02806786 ! interaction with host GO:0051701 62 25 0,000 0,0205551 0,02805194 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0205551 0,02803604 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0205551 0,02802015 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0205551 0,02800429 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0205551 0,02798844 ! immunoglobulin production GO:0002377 55 25 0,000 0,0205551 0,02797261 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0205551 0,0279568 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0205551 0,027941 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,0205551 0,02792522 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0205551 0,02790947 ! telomere organization GO:0032200 43 25 0,000 0,0205551 0,02789372 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0205551 0,027878 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0205551 0,02786229 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,02136881 0,02894896 ! embryonic pattern specification GO:0009880 44 26 0,000 0,02136881 0,02893267 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,02136881 0,0289164 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,02136881 0,02890014 ! initiation of viral infection GO:0019059 57 26 0,000 0,02136881 0,02888391 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,02136881 0,02886769 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,02136881 0,02885149 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,02136881 0,02883531 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,02136881 0,02881915 ! molting cycle process GO:0022404 50 26 0,000 0,02136881 0,028803 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,02136881 0,02878687 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,02136881 0,02877076 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,02136881 0,02875467 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,02136881 0,0287386 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,02136881 0,02872254 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,02136881 0,02870651 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,02136881 0,02869049 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,02136881 0,02867449 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,02136881 0,0286585 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,02136881 0,02864254 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,02136881 0,02862659 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,02136881 0,02861066 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,02136881 0,02859475 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,02136881 0,02857885 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,02136881 0,02856298 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,02136881 0,02854712 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,02136881 0,02853127 ! blastocyst development GO:0001824 49 26 0,000 0,02136881 0,02851545 ! leukocyte proliferation GO:0070661 52 26 0,000 0,02136881 0,02849964 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,02136881 0,02848385 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,02136881 0,02846808 ! neuron fate commitment GO:0048663 48 27 0,000 0,02218187 0,02953491 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02218187 0,02951857 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,02218187 0,02950225 ! iron ion transport GO:0006826 59 27 0,000 0,02218187 0,02948595 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,02218187 0,02946967 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02218187 0,02945341 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02218187 0,02943716 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02218187 0,02942094 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02218187 0,02940473 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02218187 0,02938853 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,02218187 0,02937236 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,02218187 0,0293562 ! autophagy GO:0006914 41 27 0,000 0,02218187 0,02934006 ! male gonad development GO:0008584 44 27 0,000 0,02218187 0,02932394 ! response to toxin GO:0009636 47 27 0,000 0,02218187 0,02930784 ! primary neural tube formation GO:0014020 51 27 0,000 0,02218187 0,02929175 ! base-excision repair GO:0006284 41 27 0,000 0,02218187 0,02927569 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02218187 0,02925964 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02218187 0,0292436 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02218187 0,02922759 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02218187 0,02921159 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02218187 0,02919561 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02218187 0,02917965 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02218187 0,0291637 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02218187 0,02914778 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02299428 0,03019882 ! circadian rhythm GO:0007623 50 28 0,000 0,02299428 0,03018235 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02299428 0,03016589 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02299428 0,03014945 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02299428 0,03013303 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02299428 0,03011662 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02299428 0,03010024 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02299428 0,03008387 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02299428 0,03006752 ! synaptogenesis GO:0007416 42 28 0,000 0,02299428 0,03005119 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02299428 0,03003487 ! lipid oxidation GO:0034440 43 28 0,000 0,02299428 0,03001858 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02299428 0,0300023 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02299428 0,02998604 ! translational initiation GO:0006413 65 29 0,000 0,02380604 0,03102781 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02380604 0,03101101 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02380604 0,03099423 ! regulation of pH GO:0006885 43 29 0,000 0,02380604 0,03097747 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02380604 0,03096072 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02380604 0,030944 ! catechol metabolic process GO:0009712 54 29 0,000 0,02380604 0,03092729 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02380604 0,0309106 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02380604 0,03089393 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02380604 0,03087727 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02380604 0,03086064 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02380604 0,03084402 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02380604 0,03082742 ! cell fate determination GO:0001709 60 29 0,000 0,02380604 0,03081083 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02380604 0,03079427 ! detection of light stimulus GO:0009583 38 29 0,000 0,02380604 0,03077772 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,02380604 0,03076119 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02380604 0,03074468 ! tissue homeostasis GO:0001894 48 29 0,000 0,02380604 0,03072819 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,02461716 0,03175812 ! zinc ion transport GO:0006829 45 30 0,000 0,02461716 0,0317411 ! membrane docking GO:0022406 61 30 0,000 0,02461716 0,03172409 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02461716 0,03170711 ! cell junction assembly GO:0034329 78 30 0,000 0,02461716 0,03169015 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02461716 0,0316732 ! acute-phase response GO:0006953 49 30 0,000 0,02461716 0,03165627 ! myofibril assembly GO:0030239 47 30 0,000 0,02461716 0,03163936 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02461716 0,03162247 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02461716 0,0316056 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02461716 0,03158874 ! phospholipid transport GO:0015914 51 30 0,000 0,02461716 0,0315719 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02461716 0,03155508 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02461716 0,03153828 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02461716 0,03152149 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02461716 0,03150473 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02461716 0,03148798 ! regulation of B cell activation GO:0050864 50 30 0,000 0,02461716 0,03147125 ! response to heat GO:0009408 50 30 0,000 0,02461716 0,03145453 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02542763 0,03247286 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02542763 0,03245564 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02542763 0,03243843 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02542763 0,03242124 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02542763 0,03240406 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02542763 0,03238691 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02542763 0,03236977 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02542763 0,03235266 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02542763 0,03233556 ! ovulation cycle process GO:0022602 49 31 0,000 0,02542763 0,03231847 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02542763 0,03230141 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02542763 0,03228437 ! peptide transport GO:0015833 55 31 0,000 0,02542763 0,03226734 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02542763 0,03225033 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02542763 0,03223334 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02542763 0,03221636 ! mesoderm formation GO:0001707 69 31 0,000 0,02542763 0,03219941 ! natural killer cell activation GO:0030101 45 31 0,000 0,02542763 0,03218247 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02542763 0,03216555 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02542763 0,03214865 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02542763 0,03213176 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02542763 0,03211489 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02542763 0,03209804 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02623745 0,03310294 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02623745 0,03308559 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02623745 0,03306826 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02623745 0,03305094 ! cholesterol transport GO:0030301 56 32 0,000 0,02623745 0,03303365 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02623745 0,03301637 ! spliceosome assembly GO:0000245 67 32 0,000 0,02623745 0,03299911 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02623745 0,03298187 ! metanephros development GO:0001656 74 32 0,000 0,02623745 0,03296465 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02623745 0,03294745 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02623745 0,03293026 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02623745 0,03291309 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02623745 0,03289594 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02623745 0,0328788 ! muscle cell development GO:0055001 49 32 0,000 0,02623745 0,03286169 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02623745 0,03284459 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02623745 0,03282751 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02623745 0,03281045 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02623745 0,03279341 ! ovulation cycle GO:0042698 51 32 0,000 0,02623745 0,03277638 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02623745 0,03275937 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02623745 0,03274238 ! hindbrain development GO:0030902 61 32 0,000 0,02623745 0,0327254 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02623745 0,03270845 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02623745 0,03269151 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02623745 0,03267459 ! gene silencing GO:0016458 65 32 0,000 0,02623745 0,03265768 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02704663 0,03364746 ! post-embryonic development GO:0009791 69 33 0,000 0,02704663 0,03363007 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02704663 0,0336127 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02704663 0,03359534 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02704663 0,03357801 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02704663 0,03356069 ! cell fate specification GO:0001708 52 33 0,000 0,02704663 0,03354339 ! sterol transport GO:0015918 57 33 0,000 0,02704663 0,03352611 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02704663 0,03350885 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02704663 0,0334916 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02704663 0,03347437 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02704663 0,03345716 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02704663 0,03343997 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02785516 0,03442193 ! glial cell differentiation GO:0010001 63 34 0,000 0,02785516 0,03440426 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02785516 0,03438661 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02785516 0,03436898 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02785516 0,03435136 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02785516 0,03433376 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02785516 0,03431618 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02785516 0,03429862 ! mismatch repair GO:0006298 46 34 0,000 0,02785516 0,03428108 ! spermatid development GO:0007286 63 34 0,000 0,02785516 0,03426355 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02785516 0,03424604 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02785516 0,03422855 ! placenta development GO:0001890 53 34 0,000 0,02785516 0,03421108 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02785516 0,03419363 ! regulation of muscle development GO:0048634 70 35 0,000 0,02866304 0,0351674 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,02866304 0,03514948 ! negative regulation of secretion GO:0051048 63 35 0,000 0,02866304 0,03513157 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,02866304 0,03511369 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,02866304 0,03509582 ! odontogenesis GO:0042476 66 35 0,000 0,02866304 0,03507797 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,02866304 0,03506013 ! female gonad development GO:0008585 58 35 0,000 0,02866304 0,03504232 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,02866304 0,03502452 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,02866304 0,03500674 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,02866304 0,03498898 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,02866304 0,03497124 ! cytokine production GO:0001816 59 35 0,000 0,02866304 0,03495351 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,02866304 0,03493581 ! neural tube formation GO:0001841 67 35 0,000 0,02866304 0,03491812 ! vesicle localization GO:0051648 64 35 0,000 0,02866304 0,03490045 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02947028 0,0358652 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02947028 0,03584707 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02947028 0,03582895 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02947028 0,03581086 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02947028 0,03579278 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02947028 0,03577472 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02947028 0,03575668 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02947028 0,03573866 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02947028 0,03572066 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02947028 0,03570267 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02947028 0,0356847 ! aerobic respiration GO:0009060 55 36 0,000 0,02947028 0,03566675 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02947028 0,03564882 ! embryonic organ development GO:0048568 57 36 0,000 0,02947028 0,03563091 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02947028 0,03561301 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03027688 0,03656936 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03027688 0,03655102 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03027688 0,03653269 ! organic anion transport GO:0015711 68 37 0,000 0,03027688 0,03651437 ! tissue remodeling GO:0048771 76 37 0,000 0,03027688 0,03649608 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03027688 0,0364778 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03027688 0,03645955 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03027688 0,03644131 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03027688 0,03642309 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03027688 0,03640488 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03027688 0,0363867 ! glycogen metabolic process GO:0005977 61 37 0,000 0,03027688 0,03636853 ! pigment metabolic process GO:0042440 80 37 0,000 0,03027688 0,03635039 ! spermatid differentiation GO:0048515 66 37 0,000 0,03027688 0,03633226 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,03027688 0,03631414 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,03108283 0,03726223 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,03108283 0,03724367 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,03108283 0,03722514 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,03108283 0,03720662 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,03108283 0,03718811 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,03108283 0,03716963 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,03108283 0,03715117 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,03108283 0,03713272 ! lipid homeostasis GO:0055088 67 38 0,000 0,03108283 0,03711429 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,03108283 0,03709588 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,03108283 0,03707749 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,03108283 0,03705912 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,03108283 0,03704076 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,03108283 0,03702242 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,03108283 0,03700411 ! glucan metabolic process GO:0044042 62 38 0,000 0,03108283 0,03698581 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,03188814 0,0379253 ! mammary gland development GO:0030879 86 39 0,000 0,03188814 0,03790656 ! ear morphogenesis GO:0042471 60 39 0,000 0,03188814 0,03788784 ! organic ether metabolic process GO:0018904 55 39 0,000 0,03188814 0,03786914 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,03188814 0,03785046 ! segmentation GO:0035282 67 39 0,000 0,03188814 0,03783179 ! ion transmembrane transport GO:0034220 66 39 0,000 0,03188814 0,03781315 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,03188814 0,03779452 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,03188814 0,03777591 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,03188814 0,03775732 ! RNA modification GO:0009451 57 39 0,000 0,03188814 0,03773875 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,03188814 0,03772019 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,03269281 0,03865302 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,03269281 0,03863404 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,03269281 0,03861507 ! feeding behavior GO:0007631 59 40 0,000 0,03269281 0,03859613 ! negative regulation of binding GO:0051100 72 40 0,000 0,03269281 0,0385772 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,03269281 0,03855829 ! mesenchymal cell development GO:0014031 87 40 0,000 0,03269281 0,03853939 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,03269281 0,03852052 ! maintenance of protein location GO:0045185 91 40 0,000 0,03269281 0,03850167 ! cytokinesis GO:0000910 72 40 0,000 0,03269281 0,03848283 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03349684 0,03940997 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03349684 0,03939071 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03349684 0,03937147 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03349684 0,03935224 ! gliogenesis GO:0042063 88 41 0,000 0,03349684 0,03933304 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03349684 0,03931385 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03349684 0,03929468 ! T cell differentiation GO:0030217 81 41 0,000 0,03349684 0,03927553 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03349684 0,0392564 ! female gamete generation GO:0007292 61 41 0,000 0,03349684 0,03923729 ! polyol metabolic process GO:0019751 66 41 0,000 0,03349684 0,03921819 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03349684 0,03919912 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03430022 0,04011975 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03430022 0,04010026 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03430022 0,04008078 ! regulation of tube size GO:0035150 71 42 0,000 0,03430022 0,04006133 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03430022 0,04004189 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03430022 0,04002247 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03430022 0,04000307 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03430022 0,03998369 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03430022 0,03996433 ! neuron migration GO:0001764 79 42 0,000 0,03430022 0,03994498 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03430022 0,03992566 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03430022 0,03990635 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,03510296 0,04082056 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,03510296 0,04080084 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,03510296 0,04078114 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,03510296 0,04076145 ! glucose transport GO:0015758 65 43 0,000 0,03510296 0,04074179 ! neural tube development GO:0021915 77 43 0,000 0,03510296 0,04072215 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,03510296 0,04070252 ! striated muscle contraction GO:0006941 77 43 0,000 0,03510296 0,04068292 ! phagocytosis GO:0006909 90 43 0,000 0,03510296 0,04066333 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,03510296 0,04064376 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03590507 0,04155247 ! hexose transport GO:0008645 67 44 0,000 0,03590507 0,0415325 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03590507 0,04151254 ! male sex differentiation GO:0046661 76 44 0,000 0,03590507 0,0414926 ! double-strand break repair GO:0006302 81 44 0,000 0,03590507 0,04147268 ! biopolymer methylation GO:0043414 84 44 0,000 0,03590507 0,04145278 ! B cell differentiation GO:0030183 107 44 0,000 0,03590507 0,0414329 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03590507 0,04141303 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03590507 0,04139319 ! developmental growth GO:0048589 82 44 0,000 0,03590507 0,04137337 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03590507 0,04135356 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03670653 0,04225642 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03670653 0,04223621 ! leukocyte migration GO:0050900 68 45 0,000 0,03670653 0,04221602 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03670653 0,04219585 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03670653 0,0421757 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,03670653 0,04215556 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03670653 0,04213545 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03670653 0,04211536 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03670653 0,04209529 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03670653 0,04207523 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03670653 0,04205519 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03750735 0,04295226 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03750735 0,04293182 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03750735 0,04291141 ! pigmentation GO:0043473 100 46 0,000 0,03750735 0,04289101 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03750735 0,04287064 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03830753 0,04376445 ! endosome transport GO:0016197 108 47 0,000 0,03830753 0,04374368 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03830753 0,04372293 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03830753 0,04370219 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03830753 0,04368148 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03830753 0,04366079 ! JNK cascade GO:0007254 91 47 0,000 0,03830753 0,04364012 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03830753 0,04361946 ! methylation GO:0032259 90 47 0,000 0,03830753 0,04359883 ! protein homooligomerization GO:0051260 76 47 0,000 0,03830753 0,04357822 ! mitochondrial transport GO:0006839 82 48 0,000 0,03910708 0,04446675 ! Notch signaling pathway GO:0007219 96 48 0,000 0,03910708 0,04444574 ! cellular component disassembly GO:0022411 86 48 0,000 0,03910708 0,04442476 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,03910708 0,04440379 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,03910708 0,04438285 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,03910708 0,04436192 ! activation of caspase activity GO:0006919 84 48 0,000 0,03910708 0,04434102 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,03910708 0,04432013 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,03910708 0,04429926 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,03910708 0,04427842 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,03910708 0,04425759 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03990599 0,04514048 ! regulation of action potential GO:0001508 95 49 0,000 0,03990599 0,04511927 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03990599 0,04509808 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03990599 0,0450769 ! regulation of ion transport GO:0043269 77 49 0,000 0,03990599 0,04505575 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03990599 0,04503462 ! peptide metabolic process GO:0006518 76 49 0,000 0,03990599 0,0450135 ! response to temperature stimulus GO:0009266 76 49 0,000 0,03990599 0,04499241 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03990599 0,04497134 ! endocrine system development GO:0035270 104 49 0,000 0,03990599 0,04495028 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03990599 0,04492925 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03990599 0,04490823 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03990599 0,04488724 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03990599 0,04486626 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,04070426 0,04574238 ! neuromuscular process GO:0050905 99 50 0,000 0,04070426 0,04572103 ! regulation of ossification GO:0030278 117 50 0,000 0,04070426 0,04569969 ! inner ear development GO:0048839 79 50 0,000 0,04070426 0,04567838 ! histone modification GO:0016570 91 50 0,000 0,04070426 0,04565708 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,04070426 0,04563581 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,04070426 0,04561455 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,04070426 0,04559331 ! positive regulation of binding GO:0051099 78 51 0,000 0,04150189 0,04646512 ! viral infectious cycle GO:0019058 99 51 0,000 0,04150189 0,04644351 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,04150189 0,04642192 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,04150189 0,04640034 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,04150189 0,04637879 ! excretion GO:0007588 83 51 0,000 0,04150189 0,04635726 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,04150189 0,04633575 ! chromatin remodeling GO:0006338 109 51 0,000 0,04150189 0,04631426 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,04150189 0,04629279 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,04150189 0,04627133 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,04150189 0,0462499 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,04150189 0,04622849 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,04150189 0,0462071 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,04229888 0,04707267 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,04229888 0,04705091 ! membrane fusion GO:0006944 110 52 0,000 0,04229888 0,04702916 ! positive regulation of growth GO:0045927 90 52 0,000 0,04229888 0,04700744 ! covalent chromatin modification GO:0016569 101 52 0,000 0,04229888 0,04698574 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,04229888 0,04696406 ! amino acid activation GO:0043038 92 52 0,000 0,04229888 0,04694239 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,04229888 0,04692075 ! synapse organization GO:0050808 85 52 0,000 0,04229888 0,04689913 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,04309524 0,04776009 ! RNA catabolic process GO:0006401 93 53 0,000 0,04309524 0,0477381 ! regulation of translational initiation GO:0006446 82 53 0,000 0,04309524 0,04771613 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,04309524 0,04769418 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,04309524 0,04767225 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,04309524 0,04765034 ! cell maturation GO:0048469 100 53 0,000 0,04309524 0,04762846 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,04309524 0,04760659 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04389096 0,04846336 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04389096 0,04844113 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04389096 0,04841892 ! cell recognition GO:0008037 85 54 0,000 0,04389096 0,04839673 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04389096 0,04837456 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04389096 0,04835241 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04389096 0,04833028 ! chloride transport GO:0006821 90 55 0,000 0,04468605 0,04918328 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04468605 0,04916079 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04468605 0,04913832 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04468605 0,04911587 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04468605 0,04909344 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04468605 0,04907104 ! gastrulation GO:0007369 112 55 0,000 0,04468605 0,04904865 ! heart morphogenesis GO:0003007 97 55 0,000 0,04468605 0,04902628 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04468605 0,04900394 ! RNA elongation GO:0006354 79 55 0,000 0,04468605 0,04898161 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0454805 0,04982973 ! sensory perception of smell GO:0007608 80 56 0,000 0,0454805 0,04980705 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0454805 0,04978439 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0454805 0,04976175 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0454805 0,04973913 ! proton transport GO:0015992 94 56 0,000 0,0454805 0,04971654 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0454805 0,04969396 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04627432 0,05053837 ! muscle fiber development GO:0048747 112 57 0,000 0,04627432 0,05051544 ! lipid modification GO:0030258 97 57 0,000 0,04627432 0,05049253 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04627432 0,05046964 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04627432 0,05044677 ! maintenance of location GO:0051235 118 57 0,000 0,04627432 0,05042392 ! hydrogen transport GO:0006818 97 58 0,000 0,04706751 0,05126502 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04706751 0,05124182 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04706751 0,05121865 ! adult behavior GO:0030534 99 58 0,000 0,04706751 0,05119549 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04706751 0,05117236 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04786006 0,05201053 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04786006 0,05198705 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,04786006 0,05196359 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,04786006 0,05194015 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,04786006 0,05191673 ! DNA catabolic process GO:0006308 86 59 0,000 0,04786006 0,05189333 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04786006 0,05186996 ! establishment of organelle localization GO:0051656 109 59 0,000 0,04786006 0,0518466 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,04865198 0,05268077 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,04865198 0,05265707 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,04865198 0,05263339 ! regulation of heart contraction GO:0008016 110 60 0,000 0,04865198 0,05260974 ! camera-type eye development GO:0043010 116 60 0,000 0,04865198 0,0525861 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,04865198 0,05256249 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,04865198 0,0525389 ! kidney development GO:0001822 122 60 0,000 0,04865198 0,05251533 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,04944327 0,05334551 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,04944327 0,0533216 ! mesoderm development GO:0007498 119 61 0,000 0,04944327 0,05329771 ! tRNA processing GO:0008033 89 61 0,000 0,04944327 0,05327385 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,04944327 0,05325 ! ear development GO:0043583 103 62 0,000 0,05023392 0,05407732 ! viral reproductive process GO:0022415 126 62 0,000 0,05023392 0,05405314 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,05023392 0,05402897 ! gonad development GO:0008406 98 62 0,000 0,05023392 0,05400483 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,05023392 0,05398071 ! regulation of mitosis GO:0007088 105 63 0,000 0,05102394 0,05480518 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,05102394 0,05478073 ! detection of external stimulus GO:0009581 91 63 0,000 0,05102394 0,05475629 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,05102394 0,05473188 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,05102394 0,05470749 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,05181334 0,05552913 ! cell redox homeostasis GO:0045454 102 64 0,000 0,05181334 0,0555044 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,05181334 0,0554797 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,05181334 0,05545502 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,05181334 0,05543036 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0526021 0,05624918 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0526021 0,05622419 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0526021 0,05619922 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0526021 0,05617428 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0526021 0,05614936 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,05339023 0,05696536 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,05339023 0,05694011 ! extracellular matrix organization GO:0030198 133 66 0,000 0,05339023 0,05691488 ! secondary metabolic process GO:0019748 116 66 0,000 0,05339023 0,05688968 ! developmental maturation GO:0021700 116 66 0,000 0,05339023 0,0568645 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,05417773 0,05767771 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,05417773 0,0576522 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,05417773 0,05762671 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,05417773 0,05760125 ! activation of MAPK activity GO:0000187 115 67 0,000 0,05417773 0,05757581 ! lung development GO:0030324 144 67 0,000 0,05417773 0,05755039 ! chromosome segregation GO:0007059 113 67 0,000 0,05417773 0,05752499 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,05417773 0,05749961 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,05417773 0,05747426 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,05417773 0,05744893 ! adaptive immune response GO:0002250 119 67 0,000 0,05417773 0,05742362 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,05417773 0,05739834 ! amino acid transport GO:0006865 125 68 0,000 0,05496461 0,05820636 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,05496461 0,05818075 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05496461 0,05815516 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05496461 0,0581296 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05496461 0,05810406 ! viral reproduction GO:0016032 134 68 0,000 0,05496461 0,05807854 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05496461 0,05805305 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05496461 0,05802758 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05575085 0,05883182 ! negative regulation of cell size GO:0045792 134 69 0,000 0,05575085 0,05880603 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05575085 0,05878026 ! urogenital system development GO:0001655 137 69 0,000 0,05575085 0,05875451 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05575085 0,05872879 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05575085 0,05870309 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05575085 0,05867741 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05653647 0,05947825 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05653647 0,05945225 ! amine catabolic process GO:0009310 117 71 0,000 0,05732146 0,06025139 ! reproductive structure development GO:0048608 113 71 0,000 0,05732146 0,06022508 ! appendage development GO:0048736 136 71 0,000 0,05732146 0,06019879 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05732146 0,06017253 ! B cell activation GO:0042113 160 71 0,000 0,05732146 0,06014629 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05732146 0,06012007 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05732146 0,06009387 ! acute inflammatory response GO:0002526 113 72 0,000 0,05810582 0,06088964 ! regulation of caspase activity GO:0043281 122 72 0,000 0,05810582 0,06086313 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,05810582 0,06083664 ! carbohydrate transport GO:0008643 110 72 0,000 0,05810582 0,06081018 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,05810582 0,06078374 ! respiratory system development GO:0060541 153 72 0,000 0,05810582 0,06075733 ! regulation of blood pressure GO:0008217 125 73 0,000 0,05888956 0,06155008 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,05888956 0,06152335 ! axon guidance GO:0007411 139 73 0,000 0,05888956 0,06149665 ! fertilization GO:0009566 90 73 0,000 0,05888956 0,06146997 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,05967267 0,06226038 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,05967267 0,06223339 ! neurotransmitter transport GO:0006836 123 74 0,000 0,05967267 0,06220643 ! exocytosis GO:0006887 133 74 0,000 0,05967267 0,06217949 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,05967267 0,06215257 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,05967267 0,06212568 ! organelle localization GO:0051640 136 74 0,000 0,05967267 0,06209881 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,06045515 0,06288591 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,06045515 0,06285873 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,06045515 0,06283158 ! rhythmic process GO:0048511 128 75 0,000 0,06045515 0,06280445 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,06045515 0,06277734 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,06123701 0,0635618 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,06123701 0,06353439 ! defense response to bacterium GO:0042742 89 76 0,000 0,06123701 0,06350701 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,06123701 0,06347964 ! regulation of catabolic process GO:0009894 161 76 0,000 0,06123701 0,06345231 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,06201825 0,06423414 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,06201825 0,0642065 ! blood coagulation GO:0007596 146 78 0,000 0,06279886 0,06498669 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,06279886 0,06495875 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,06279886 0,06493083 ! protein oligomerization GO:0051259 139 78 0,000 0,06279886 0,06490294 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,06357885 0,06568085 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,06357885 0,06565266 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,06357885 0,0656245 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,06435821 0,06640045 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,06435821 0,06637199 ! protein import into nucleus GO:0006606 158 80 0,000 0,06435821 0,06634355 ! inorganic anion transport GO:0015698 138 80 0,000 0,06435821 0,06631514 ! T cell activation GO:0042110 168 81 0,000 0,06513695 0,06708883 ! digestion GO:0007586 112 81 0,000 0,06513695 0,06706012 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06513695 0,06703144 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06513695 0,06700278 ! nuclear import GO:0051170 161 81 0,000 0,06513695 0,06697415 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06513695 0,06694554 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06591507 0,06771633 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06591507 0,06768743 ! response to drug GO:0042493 143 82 0,000 0,06591507 0,06765856 ! response to nutrient GO:0007584 125 82 0,000 0,06591507 0,0676297 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06591507 0,06760088 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06591507 0,06757207 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06669257 0,06834 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,06746944 0,06910663 ! hemostasis GO:0007599 158 84 0,000 0,06746944 0,06907722 ! negative regulation of transport GO:0051051 153 84 0,000 0,06746944 0,06904784 ! negative regulation of growth GO:0045926 155 84 0,000 0,06746944 0,06901848 ! nucleosome assembly GO:0006334 122 85 0,000 0,0682457 0,06978289 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0682457 0,06975325 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,0682457 0,06972363 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,06902133 0,07048613 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,06902133 0,07045623 ! chromatin assembly GO:0031497 124 86 0,000 0,06902133 0,07042635 ! tube morphogenesis GO:0035239 176 86 0,000 0,06902133 0,07039649 ! mitochondrion organization GO:0007005 148 86 0,000 0,06902133 0,07036666 ! amine transport GO:0015837 155 86 0,000 0,06902133 0,07033686 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,06979635 0,07109653 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,06979635 0,07106644 ! protein localization in nucleus GO:0034504 176 87 0,000 0,06979635 0,07103638 ! regulation of protein transport GO:0051223 154 87 0,000 0,06979635 0,07100635 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,07057074 0,07176382 ! regulation of DNA binding GO:0051101 155 88 0,000 0,07057074 0,0717335 ! gland development GO:0048732 206 88 0,000 0,07057074 0,07170321 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,07057074 0,07167294 ! cellular defense response GO:0006968 114 89 0,000 0,07134452 0,07242823 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,07134452 0,07239768 ! ossification GO:0001503 188 90 0,000 0,07211768 0,0731514 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,07211768 0,07312058 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,07211768 0,07308978 ! sex differentiation GO:0007548 145 90 0,000 0,07211768 0,073059 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,07211768 0,07302825 ! bone development GO:0060348 189 91 0,000 0,07289022 0,07377949 ! sterol metabolic process GO:0016125 152 91 0,000 0,07289022 0,07374847 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,07289022 0,07371747 ! regulation of defense response GO:0031347 149 92 0,000 0,07366214 0,07446685 ! nucleosome organization GO:0034728 138 92 0,000 0,07366214 0,07443557 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,07366214 0,07440433 ! vitamin metabolic process GO:0006766 139 92 0,000 0,07366214 0,0743731 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,07443344 0,07512033 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,07443344 0,07508883 ! regulation of membrane potential GO:0042391 164 93 0,000 0,07443344 0,07505736 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,07520413 0,07580274 ! female pregnancy GO:0007565 164 94 0,000 0,07520413 0,075771 ! transcription initiation GO:0006352 153 94 0,000 0,07520413 0,07573928 ! regulation of T cell activation GO:0050863 158 94 0,000 0,07520413 0,07570759 ! forebrain development GO:0030900 188 95 0,000 0,07597421 0,07645083 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07674366 0,07719283 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07674366 0,07716057 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07674366 0,07712834 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07674366 0,07709614 ! detection of stimulus GO:0051606 151 96 0,000 0,07674366 0,07706396 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0775125 0,07780354 ! protein ubiquitination GO:0016567 217 97 0,000 0,0775125 0,07777109 ! hormone metabolic process GO:0042445 157 97 0,000 0,0775125 0,07773868 ! regulation of protein localization GO:0032880 176 97 0,000 0,0775125 0,07770629 ! response to virus GO:0009615 160 98 0,000 0,07828073 0,07844375 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,07828073 0,07841109 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,07828073 0,07837846 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,07904835 0,07911411 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,07904835 0,07908121 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,07981534 0,07981534