pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/51022-5-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cell redox homeostasis GO:0045454 102 64 4,000 4,198E-10 1,01E-06 ! response to hydrogen peroxide GO:0042542 50 32 3,000 4,022E-09 4,838E-06 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 7,438E-09 5,965E-06 ! response to reactive oxygen species GO:0000302 67 42 3,000 1,247E-08 7,5E-06 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 1,784E-08 8,583E-06 ! protein oligomerization GO:0051259 139 78 3,000 1,566E-07 6,281E-05 ! cellular response to hydrogen peroxide GO:0070301 23 18 2,000 1,727E-07 5,934E-05 GO:0042744|hydrogen peroxide catabolic process, ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 3,253E-07 9,784E-05 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 3,253E-07 8,697E-05 ! hydrogen peroxide metabolic process GO:0042743 33 25 2,000 4,853E-07 1,168E-04 ! cellular response to oxidative stress GO:0034599 39 26 2,000 5,484E-07 1,199E-04 ! mesoderm formation GO:0001707 69 31 2,000 9,462E-07 1,897E-04 ! formation of primary germ layer GO:0001704 72 33 2,000 1,148E-06 2,124E-04 ! mesoderm morphogenesis GO:0048332 76 34 2,000 1,258E-06 2,162E-04 ! response to redox state GO:0051775 5 5 1,000 3,766E-06 6,041E-04 GO:0006980|redox signal response, ! response to temperature stimulus GO:0009266 76 49 2,000 3,85E-06 5,79E-04 ! regulation of translational initiation GO:0006446 82 53 2,000 4,888E-06 6,918E-04 ! gastrulation GO:0007369 112 55 2,000 5,47E-06 7,311E-04 ! mesoderm development GO:0007498 119 61 2,000 7,486E-06 9,479E-04 ! protein thiol-disulfide exchange GO:0006467 9 7 1,000 7,903E-06 9,508E-04 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 8,655E-06 9,917E-04 ! protein heterooligomerization GO:0051291 16 9 1,000 1,354E-05 1,481E-03 ! glutathione metabolic process GO:0006749 39 27 1,000 1,311E-04 0,01371533 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,515E-04 0,015192 ! response to heat GO:0009408 50 30 1,000 1,623E-04 0,01562018 ! peptide metabolic process GO:0006518 76 49 1,000 4,357E-04 0,04031508 ! response to unfolded protein GO:0006986 131 85 1,000 1,305E-03 0,11626836 ! response to protein stimulus GO:0051789 149 91 1,000 1,493E-03 0,12831399 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 3,151E-03 0,26139084 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,151E-03 0,25267781 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,151E-03 0,24452691 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,151E-03 0,23688545 ! neuron fate determination GO:0048664 7 5 0,000 3,151E-03 0,2297071 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,151E-03 0,22295101 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,151E-03 0,21658098 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,151E-03 0,21056484 ! polyol transport GO:0015791 12 5 0,000 3,151E-03 0,2048739 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,151E-03 0,19948248 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,151E-03 0,19436754 ! response to superoxide GO:0000303 10 5 0,000 3,151E-03 0,18950836 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,151E-03 0,1848862 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,151E-03 0,18048415 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,151E-03 0,17628684 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,151E-03 0,17228032 ! female meiosis GO:0007143 7 5 0,000 3,151E-03 0,16845187 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,151E-03 0,16478988 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,151E-03 0,16128371 ! cobalt ion transport GO:0006824 11 5 0,000 3,151E-03 0,15792363 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,151E-03 0,1547007 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,151E-03 0,15160669 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,151E-03 0,148634 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,151E-03 0,14577566 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,151E-03 0,14302517 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,151E-03 0,14037656 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,151E-03 0,13782426 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,151E-03 0,13536311 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,151E-03 0,13298832 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,151E-03 0,13069542 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,151E-03 0,12848024 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,151E-03 0,1263389 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,151E-03 0,12426777 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,151E-03 0,12226346 ! negative chemotaxis GO:0050919 14 5 0,000 3,151E-03 0,12032277 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,151E-03 0,11844272 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,151E-03 0,11662053 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,151E-03 0,11485355 ! behavioral response to pain GO:0048266 9 5 0,000 3,151E-03 0,11313932 ! clathrin coat assembly GO:0048268 14 5 0,000 3,151E-03 0,1114755 ! Notch receptor processing GO:0007220 8 5 0,000 3,151E-03 0,10985992 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,151E-03 0,10829049 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,151E-03 0,10676527 ! micturition GO:0060073 9 5 0,000 3,151E-03 0,10528242 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,151E-03 0,1038402 ! copulation GO:0007620 9 5 0,000 3,151E-03 0,10243695 ! glial cell fate commitment GO:0021781 13 5 0,000 3,151E-03 0,10107112 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,151E-03 0,09974124 ! spermidine metabolic process GO:0008216 7 5 0,000 3,151E-03 0,0984459 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,151E-03 0,09718377 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,151E-03 0,0959536 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,151E-03 0,09475418 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,151E-03 0,09358437 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,151E-03 0,0924431 ! grooming behavior GO:0007625 6 5 0,000 3,151E-03 0,09132933 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,151E-03 0,09024207 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,151E-03 0,0891804 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,151E-03 0,08814342 ! response to protozoan GO:0001562 10 5 0,000 3,151E-03 0,08713028 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,151E-03 0,08614016 ! lymph vessel development GO:0001945 10 5 0,000 3,151E-03 0,08517229 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,151E-03 0,08422594 ! endochondral ossification GO:0001958 16 5 0,000 3,151E-03 0,08330038 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,151E-03 0,08239494 ! parathyroid gland development GO:0060017 13 5 0,000 3,151E-03 0,08150897 ! anagen GO:0042640 6 5 0,000 3,151E-03 0,08064185 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,151E-03 0,07979299 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 3,151E-03 0,07896182 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,151E-03 0,07814778 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,151E-03 0,07735035 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,151E-03 0,07656903 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,151E-03 0,07580334 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,151E-03 0,07505281 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,151E-03 0,074317 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,151E-03 0,07359548 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,151E-03 0,07288783 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,151E-03 0,07219366 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,151E-03 0,07151259 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,151E-03 0,07084425 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,151E-03 0,07018828 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,151E-03 0,06954435 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 3,151E-03 0,06891213 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,151E-03 0,0682913 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,151E-03 0,06768156 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,151E-03 0,0670826 ! histidine catabolic process GO:0006548 6 5 0,000 3,151E-03 0,06649416 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,151E-03 0,06591595 ! microvillus organization GO:0032528 7 5 0,000 3,151E-03 0,06534771 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,151E-03 0,06478918 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,151E-03 0,06424012 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,151E-03 0,06370029 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,151E-03 0,06316945 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,151E-03 0,06264739 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,151E-03 0,06213389 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,151E-03 0,06162873 ! polyol catabolic process GO:0046174 7 5 0,000 3,151E-03 0,06113173 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,151E-03 0,06064267 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,151E-03 0,06016138 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,151E-03 0,05968767 ! muscle cell migration GO:0014812 8 5 0,000 3,151E-03 0,05922136 ! mitochondrial fission GO:0000266 8 5 0,000 3,151E-03 0,05876228 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,151E-03 0,05831026 ! mRNA transcription GO:0009299 9 5 0,000 3,151E-03 0,05786515 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,151E-03 0,05742677 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,151E-03 0,05699499 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,151E-03 0,05656966 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,151E-03 0,05615062 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,151E-03 0,05573775 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,151E-03 0,05533091 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,151E-03 0,05492996 ! response to food GO:0032094 6 5 0,000 3,151E-03 0,05453478 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,151E-03 0,05414524 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,151E-03 0,05376124 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,151E-03 0,05338264 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,151E-03 0,05300933 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,151E-03 0,05264121 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,151E-03 0,05227817 ! forebrain neuron development GO:0021884 13 5 0,000 3,151E-03 0,0519201 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,151E-03 0,0515669 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,151E-03 0,05121847 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,151E-03 0,05087473 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,151E-03 0,05053556 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,151E-03 0,05020089 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,151E-03 0,04987062 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,151E-03 0,04954467 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,151E-03 0,04922295 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,151E-03 0,04890538 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,151E-03 0,04859189 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,151E-03 0,04828238 ! basic amino acid transport GO:0015802 11 5 0,000 3,151E-03 0,0479768 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,151E-03 0,04767506 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,151E-03 0,04737709 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,151E-03 0,04708282 ! depyrimidination GO:0045008 10 5 0,000 3,151E-03 0,04679219 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,151E-03 0,04650512 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,151E-03 0,04622155 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,151E-03 0,04594142 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,151E-03 0,04566466 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,151E-03 0,04539122 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,151E-03 0,04512104 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,151E-03 0,04485405 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,151E-03 0,0445902 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,151E-03 0,04432944 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,151E-03 0,04407171 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,151E-03 0,04381696 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,151E-03 0,04356514 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,151E-03 0,0433162 ! response to arsenic GO:0046685 10 5 0,000 3,151E-03 0,04307008 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,151E-03 0,04282675 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,151E-03 0,04258615 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,151E-03 0,04234824 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,151E-03 0,04211297 ! response to cadmium ion GO:0046686 7 5 0,000 3,151E-03 0,0418803 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,151E-03 0,04165019 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,151E-03 0,04142259 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,151E-03 0,04119747 ! decidualization GO:0046697 11 5 0,000 3,151E-03 0,04097478 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,151E-03 0,04075449 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,151E-03 0,04053655 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,151E-03 0,04032093 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,151E-03 0,04010759 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,151E-03 0,0398965 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,151E-03 0,03968761 ! neural tube patterning GO:0021532 7 5 0,000 3,151E-03 0,03948091 ! embryonic cleavage GO:0040016 6 5 0,000 3,151E-03 0,03927634 ! peroxisome fission GO:0016559 5 5 0,000 3,151E-03 0,03907389 ! histone demethylation GO:0016577 10 5 0,000 3,151E-03 0,03887351 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,151E-03 0,03867517 ! mitotic recombination GO:0006312 9 5 0,000 3,151E-03 0,03847885 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,151E-03 0,03828452 ! metaphase plate congression GO:0051310 7 5 0,000 3,151E-03 0,03809213 ! regulation of sterol transport GO:0032371 7 5 0,000 3,151E-03 0,03790167 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,151E-03 0,03771311 ! enteric nervous system development GO:0048484 8 5 0,000 3,151E-03 0,03752641 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,151E-03 0,03734155 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,151E-03 0,0371585 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,151E-03 0,03697724 ! muscle cell proliferation GO:0033002 11 5 0,000 3,151E-03 0,03679774 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,151E-03 0,03661997 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,151E-03 0,03644391 ! plasminogen activation GO:0031639 5 5 0,000 3,151E-03 0,03626954 ! B cell homeostasis GO:0001782 13 5 0,000 3,151E-03 0,03609683 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,151E-03 0,03592575 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,151E-03 0,03575629 ! metaphase GO:0051323 8 5 0,000 3,151E-03 0,03558842 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,151E-03 0,03542212 ! cellular response to nutrient GO:0031670 8 5 0,000 3,151E-03 0,03525737 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,151E-03 0,03509414 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,151E-03 0,03493242 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,151E-03 0,03477218 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,151E-03 0,0346134 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,151E-03 0,03445606 ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,151E-03 0,03430015 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,151E-03 0,03414565 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,151E-03 0,03399253 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,151E-03 0,03384078 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,151E-03 0,03369037 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,151E-03 0,0335413 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,151E-03 0,03339354 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,151E-03 0,03324708 ! striatum development GO:0021756 9 5 0,000 3,151E-03 0,0331019 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,151E-03 0,03295798 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 3,151E-03 0,0328153 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,151E-03 0,03267385 ! glial cell migration GO:0008347 11 5 0,000 3,151E-03 0,03253362 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,151E-03 0,03239459 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,151E-03 0,03225674 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,151E-03 0,03212006 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,151E-03 0,03198453 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,151E-03 0,03185014 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,151E-03 0,03171688 ! neuroprotection GO:0043526 6 5 0,000 3,151E-03 0,03158473 ! neural plate development GO:0001840 8 5 0,000 3,151E-03 0,03145367 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,151E-03 0,0313237 ! regulation of sensory perception GO:0051931 7 5 0,000 3,151E-03 0,03119479 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,151E-03 0,03106694 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,151E-03 0,03094014 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,151E-03 0,03081437 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,151E-03 0,03068961 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,151E-03 0,03056586 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,151E-03 0,03044311 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,151E-03 0,03032134 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,151E-03 0,03020053 ! spindle assembly GO:0051225 6 5 0,000 3,151E-03 0,03008069 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,151E-03 0,0299618 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,151E-03 0,02984384 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,151E-03 0,0297268 ! drug metabolic process GO:0017144 6 5 0,000 3,151E-03 0,02961068 ! stem cell division GO:0017145 11 5 0,000 3,151E-03 0,02949546 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,151E-03 0,02938114 ! organ regeneration GO:0031100 7 5 0,000 3,151E-03 0,0292677 ! carnitine metabolic process GO:0009437 7 5 0,000 3,151E-03 0,02915513 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,151E-03 0,02904343 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,151E-03 0,02893257 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 3,78E-03 0,03457674 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 3,78E-03 0,03444577 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 3,78E-03 0,03431579 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,78E-03 0,03418678 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 3,78E-03 0,03405874 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 3,78E-03 0,03393165 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 3,78E-03 0,03380552 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 3,78E-03 0,03368031 ! sleep GO:0030431 13 6 0,000 3,78E-03 0,03355603 ! response to oxygen radical GO:0000305 11 6 0,000 3,78E-03 0,03343266 ! positive regulation of axon extension GO:0045773 11 6 0,000 3,78E-03 0,0333102 ! myoblast cell fate commitment GO:0048625 16 6 0,000 3,78E-03 0,03318863 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 3,78E-03 0,03306794 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 3,78E-03 0,03294813 ! regulation of interferon-beta production GO:0032648 8 6 0,000 3,78E-03 0,03282918 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 3,78E-03 0,03271109 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 3,78E-03 0,03259385 ! forebrain regionalization GO:0021871 8 6 0,000 3,78E-03 0,03247744 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 3,78E-03 0,03236186 ! male meiosis GO:0007140 7 6 0,000 3,78E-03 0,0322471 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 3,78E-03 0,03213316 ! response to zinc ion GO:0010043 9 6 0,000 3,78E-03 0,03202001 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 3,78E-03 0,03190766 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 3,78E-03 0,0317961 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 3,78E-03 0,03168531 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 3,78E-03 0,03157529 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 3,78E-03 0,03146603 ! malate metabolic process GO:0006108 11 6 0,000 3,78E-03 0,03135753 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 3,78E-03 0,03124977 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 3,78E-03 0,03114275 ! protein refolding GO:0042026 15 6 0,000 3,78E-03 0,03103646 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 3,78E-03 0,0309309 ! opsonization GO:0008228 8 6 0,000 3,78E-03 0,03082605 ! mating behavior GO:0007617 7 6 0,000 3,78E-03 0,0307219 ! neuron remodeling GO:0016322 15 6 0,000 3,78E-03 0,03061846 ! erythrocyte maturation GO:0043249 7 6 0,000 3,78E-03 0,03051572 ! embryonic hemopoiesis GO:0035162 14 6 0,000 3,78E-03 0,03041366 ! equilibrioception GO:0050957 14 6 0,000 3,78E-03 0,03031228 ! protein amino acid dealkylation GO:0008214 12 6 0,000 3,78E-03 0,03021157 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 3,78E-03 0,03011153 ! photoreceptor cell development GO:0042461 10 6 0,000 3,78E-03 0,03001216 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 3,78E-03 0,02991343 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 3,78E-03 0,02981536 ! response to interferon-gamma GO:0034341 15 6 0,000 3,78E-03 0,02971792 ! toxin metabolic process GO:0009404 11 6 0,000 3,78E-03 0,02962112 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 3,78E-03 0,02952495 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 3,78E-03 0,0294294 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 3,78E-03 0,02933446 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 3,78E-03 0,02924014 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 3,78E-03 0,02914642 ! cGMP-mediated signaling GO:0019934 13 6 0,000 3,78E-03 0,0290533 ! activation of MAPKKK activity GO:0000185 12 6 0,000 3,78E-03 0,02896078 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 3,78E-03 0,02886884 ! thymic T cell selection GO:0045061 12 6 0,000 3,78E-03 0,02877748 ! protein lipoylation GO:0009249 10 6 0,000 3,78E-03 0,0286867 ! cysteine metabolic process GO:0006534 10 6 0,000 3,78E-03 0,02859649 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 3,78E-03 0,02850684 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 3,78E-03 0,02841776 ! glutamate catabolic process GO:0006538 10 6 0,000 3,78E-03 0,02832923 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 3,78E-03 0,02824125 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 3,78E-03 0,02815382 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 3,78E-03 0,02806692 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 3,78E-03 0,02798056 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 3,78E-03 0,02789473 ! hyperosmotic response GO:0006972 9 6 0,000 3,78E-03 0,02780943 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 3,78E-03 0,02772464 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 3,78E-03 0,02764038 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 3,78E-03 0,02755662 ! urea metabolic process GO:0019627 7 6 0,000 3,78E-03 0,02747336 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 3,78E-03 0,02739061 ! neutrophil activation GO:0042119 8 6 0,000 3,78E-03 0,02730836 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 3,78E-03 0,0272266 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 3,78E-03 0,02714532 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 3,78E-03 0,02706453 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,78E-03 0,02698422 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 3,78E-03 0,02690439 ! neuron apoptosis GO:0051402 9 6 0,000 3,78E-03 0,02682503 ! nucleoside salvage GO:0043174 9 6 0,000 3,78E-03 0,02674613 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 3,78E-03 0,02666769 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 3,78E-03 0,02658972 ! T cell mediated immunity GO:0002456 16 6 0,000 3,78E-03 0,0265122 ! negative regulation of platelet activation GO:0010544 9 6 0,000 3,78E-03 0,02643513 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 3,78E-03 0,0263585 ! carnitine transport GO:0015879 10 6 0,000 3,78E-03 0,02628232 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 3,78E-03 0,02620658 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,78E-03 0,02613127 ! positive regulation of exocytosis GO:0045921 8 6 0,000 3,78E-03 0,0260564 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 3,78E-03 0,02598195 ! 5S class rRNA transcription GO:0042791 11 6 0,000 3,78E-03 0,02590793 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 3,78E-03 0,02583433 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 3,78E-03 0,02576114 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 3,78E-03 0,02568837 ! sodium ion homeostasis GO:0055078 11 6 0,000 3,78E-03 0,02561601 ! establishment of spindle localization GO:0051293 12 6 0,000 3,78E-03 0,02554405 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 3,78E-03 0,0254725 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 3,78E-03 0,02540135 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 3,78E-03 0,02533059 ! neural nucleus development GO:0048857 14 6 0,000 3,78E-03 0,02526023 ! response to UV-C GO:0010225 11 6 0,000 3,78E-03 0,02519026 ! astrocyte development GO:0014002 15 6 0,000 3,78E-03 0,02512067 ! protein targeting to lysosome GO:0006622 10 6 0,000 3,78E-03 0,02505147 ! purine base biosynthetic process GO:0009113 17 6 0,000 3,78E-03 0,02498265 ! interaction with symbiont GO:0051702 13 6 0,000 3,78E-03 0,0249142 ! regulation of dendrite development GO:0050773 16 6 0,000 3,78E-03 0,02484613 ! skeletal muscle contraction GO:0003009 6 6 0,000 3,78E-03 0,02477843 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 3,78E-03 0,0247111 ! response to copper ion GO:0046688 10 6 0,000 3,78E-03 0,02464413 ! response to exogenous dsRNA GO:0043330 10 6 0,000 3,78E-03 0,02457752 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 3,78E-03 0,02451128 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,78E-03 0,02444539 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 3,78E-03 0,02437985 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 3,78E-03 0,02431466 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 3,78E-03 0,02424982 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,78E-03 0,02418533 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,78E-03 0,02412118 ! hair follicle maturation GO:0048820 7 6 0,000 3,78E-03 0,02405736 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 3,78E-03 0,02399389 ! Schwann cell development GO:0014044 15 6 0,000 3,78E-03 0,02393075 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 3,78E-03 0,02386794 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 3,78E-03 0,02380545 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 3,78E-03 0,0237433 ! subpallium development GO:0021544 10 6 0,000 3,78E-03 0,02368147 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 3,78E-03 0,02361996 ! histone ubiquitination GO:0016574 8 6 0,000 3,78E-03 0,02355877 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 3,78E-03 0,02349789 ! maintenance of organ identity GO:0048496 9 6 0,000 3,78E-03 0,02343733 ! G2 phase GO:0051319 16 6 0,000 3,78E-03 0,02337708 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 3,78E-03 0,02331714 ! establishment of planar polarity GO:0001736 7 6 0,000 3,78E-03 0,0232575 ! regulation of mast cell activation GO:0033003 12 6 0,000 3,78E-03 0,02319817 ! membrane to membrane docking GO:0022614 14 6 0,000 3,78E-03 0,02313914 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 3,78E-03 0,02308042 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 3,78E-03 0,02302198 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 3,78E-03 0,02296385 ! receptor internalization GO:0031623 10 6 0,000 3,78E-03 0,022906 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 3,78E-03 0,02284845 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 3,78E-03 0,02279119 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,78E-03 0,02273421 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 3,78E-03 0,02267752 ! protein deubiquitination GO:0016579 14 6 0,000 3,78E-03 0,0226211 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 3,78E-03 0,02256497 ! protein destabilization GO:0031648 9 6 0,000 3,78E-03 0,02250912 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 3,78E-03 0,02245354 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 3,78E-03 0,02239824 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,78E-03 0,0223432 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 3,78E-03 0,02228844 ! progesterone metabolic process GO:0042448 10 6 0,000 3,78E-03 0,02223395 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 3,78E-03 0,02217972 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 3,78E-03 0,02212575 ! negative regulation of axon extension GO:0030517 21 6 0,000 3,78E-03 0,02207205 ! removal of superoxide radicals GO:0019430 11 6 0,000 3,78E-03 0,0220186 ! triglyceride catabolic process GO:0019433 10 6 0,000 3,78E-03 0,02196542 ! determination of adult lifespan GO:0008340 15 6 0,000 3,78E-03 0,02191249 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 3,78E-03 0,02185982 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 3,78E-03 0,02180739 ! cerebellar cortex formation GO:0021697 8 6 0,000 3,78E-03 0,02175522 ! catecholamine transport GO:0051937 9 6 0,000 3,78E-03 0,0217033 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 3,78E-03 0,02165163 ! sensory cilium assembly GO:0035058 10 6 0,000 3,78E-03 0,0216002 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,78E-03 0,02154901 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 3,78E-03 0,02149807 ! maternal placenta development GO:0001893 12 6 0,000 3,78E-03 0,02144737 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 3,78E-03 0,0213969 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 3,78E-03 0,02134667 ! negative regulation of B cell activation GO:0050869 13 6 0,000 3,78E-03 0,02129668 ! protein amino acid prenylation GO:0018346 16 6 0,000 3,78E-03 0,02124692 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 3,78E-03 0,0211974 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 3,78E-03 0,0211481 ! positive regulation of coagulation GO:0050820 12 6 0,000 3,78E-03 0,02109903 ! tRNA transcription GO:0009304 14 7 0,000 4,408E-03 0,02455122 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 4,408E-03 0,02449452 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 4,408E-03 0,02443808 ! behavioral response to cocaine GO:0048148 14 7 0,000 4,408E-03 0,0243819 ! regulation of helicase activity GO:0051095 15 7 0,000 4,408E-03 0,02432598 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 4,408E-03 0,02427032 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 4,408E-03 0,0242149 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 4,408E-03 0,02415975 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 4,408E-03 0,02410484 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 4,408E-03 0,02405018 ! prostate gland development GO:0030850 13 7 0,000 4,408E-03 0,02399577 ! nucleotide-sugar transport GO:0015780 12 7 0,000 4,408E-03 0,0239416 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,408E-03 0,02388768 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 4,408E-03 0,023834 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 4,408E-03 0,02378056 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,408E-03 0,02372736 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 4,408E-03 0,02367439 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 4,408E-03 0,02362167 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 4,408E-03 0,02356917 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 4,408E-03 0,02351691 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 4,408E-03 0,02346489 ! SMAD protein complex assembly GO:0007183 12 7 0,000 4,408E-03 0,02341309 ! glycolipid transport GO:0046836 10 7 0,000 4,408E-03 0,02336152 ! protein amino acid sulfation GO:0006477 10 7 0,000 4,408E-03 0,02331017 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 4,408E-03 0,02325905 ! neuron adhesion GO:0007158 12 7 0,000 4,408E-03 0,02320816 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 4,408E-03 0,02315749 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 4,408E-03 0,02310703 ! actin-myosin filament sliding GO:0033275 11 7 0,000 4,408E-03 0,0230568 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 4,408E-03 0,02300679 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 4,408E-03 0,02295699 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 4,408E-03 0,0229074 ! mRNA stabilization GO:0048255 18 7 0,000 4,408E-03 0,02285803 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 4,408E-03 0,02280888 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 4,408E-03 0,02275993 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 4,408E-03 0,0227112 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 4,408E-03 0,02266267 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,408E-03 0,02261435 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 4,408E-03 0,02256623 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 4,408E-03 0,02251832 ! lipoprotein transport GO:0042953 14 7 0,000 4,408E-03 0,02247061 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,408E-03 0,0224231 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,408E-03 0,0223758 ! rhythmic behavior GO:0007622 15 7 0,000 4,408E-03 0,02232869 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 4,408E-03 0,02228178 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 4,408E-03 0,02223507 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 4,408E-03 0,02218855 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 4,408E-03 0,02214223 ! regulation of odontogenesis GO:0042481 13 7 0,000 4,408E-03 0,0220961 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 4,408E-03 0,02205016 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 4,408E-03 0,02200442 ! mechanosensory behavior GO:0007638 14 7 0,000 4,408E-03 0,02195886 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 4,408E-03 0,02191349 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,408E-03 0,02186831 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 4,408E-03 0,02182331 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,408E-03 0,0217785 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,408E-03 0,02173387 ! spinal cord patterning GO:0021511 13 7 0,000 4,408E-03 0,02168942 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 4,408E-03 0,02164516 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 4,408E-03 0,02160108 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 4,408E-03 0,02155717 ! adrenal gland development GO:0030325 17 7 0,000 4,408E-03 0,02151344 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 4,408E-03 0,0214699 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 4,408E-03 0,02142652 ! ovulation GO:0030728 9 7 0,000 4,408E-03 0,02138332 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 4,408E-03 0,0213403 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 4,408E-03 0,02129745 ! microtubule nucleation GO:0007020 20 7 0,000 4,408E-03 0,02125477 ! proline biosynthetic process GO:0006561 10 7 0,000 4,408E-03 0,02121226 ! thyroid hormone generation GO:0006590 13 7 0,000 4,408E-03 0,02116992 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 4,408E-03 0,02112775 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 4,408E-03 0,02108574 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 4,408E-03 0,02104391 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,408E-03 0,02100223 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,408E-03 0,02096073 ! galactose metabolic process GO:0006012 13 7 0,000 4,408E-03 0,02091938 ! vesicle fusion GO:0006906 17 7 0,000 4,408E-03 0,02087821 ! response to dietary excess GO:0002021 8 7 0,000 4,408E-03 0,02083719 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 4,408E-03 0,02079633 ! intracellular pH reduction GO:0051452 11 7 0,000 4,408E-03 0,02075563 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 4,408E-03 0,02071509 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 4,408E-03 0,02067471 ! organ growth GO:0035265 15 7 0,000 4,408E-03 0,02063449 ! purine salvage GO:0043101 10 7 0,000 4,408E-03 0,02059442 ! nucleoside transport GO:0015858 8 7 0,000 4,408E-03 0,02055451 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 4,408E-03 0,02051475 ! parturition GO:0007567 14 7 0,000 4,408E-03 0,02047515 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 4,408E-03 0,0204357 ! rRNA modification GO:0000154 14 7 0,000 4,408E-03 0,0203964 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 4,408E-03 0,02035725 ! spindle checkpoint GO:0031577 15 7 0,000 4,408E-03 0,02031825 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 4,408E-03 0,0202794 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 4,408E-03 0,0202407 ! macrophage differentiation GO:0030225 11 7 0,000 4,408E-03 0,02020215 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,408E-03 0,02016374 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 4,408E-03 0,02012548 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 4,408E-03 0,02008736 ! hyaluronan metabolic process GO:0030212 8 7 0,000 4,408E-03 0,02004939 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 4,408E-03 0,02001156 ! anterograde axon cargo transport GO:0008089 18 7 0,000 4,408E-03 0,01997388 ! fibrinolysis GO:0042730 10 7 0,000 4,408E-03 0,01993633 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 4,408E-03 0,01989893 ! eating behavior GO:0042755 7 7 0,000 4,408E-03 0,01986166 ! B cell lineage commitment GO:0002326 21 7 0,000 4,408E-03 0,01982454 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 4,408E-03 0,01978755 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 4,408E-03 0,0197507 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 4,408E-03 0,01971399 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 4,408E-03 0,01967742 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 4,408E-03 0,01964098 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 4,408E-03 0,01960467 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 4,408E-03 0,0195685 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 4,408E-03 0,01953246 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 4,408E-03 0,01949656 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 4,408E-03 0,01946079 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 4,408E-03 0,01942514 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 4,408E-03 0,01938963 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 4,408E-03 0,01935425 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 4,408E-03 0,01931899 ! regulation of meiosis GO:0040020 12 7 0,000 4,408E-03 0,01928387 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 4,408E-03 0,01924887 ! T cell lineage commitment GO:0002360 16 7 0,000 4,408E-03 0,019214 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 4,408E-03 0,01917926 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 4,408E-03 0,01914464 ! oxygen homeostasis GO:0032364 12 7 0,000 4,408E-03 0,01911014 ! transcription termination GO:0006353 13 7 0,000 4,408E-03 0,01907577 ! response to tumor cell GO:0002347 13 7 0,000 4,408E-03 0,01904152 ! regulation of respiratory burst GO:0060263 11 7 0,000 4,408E-03 0,0190074 ! coenzyme A metabolic process GO:0015936 12 7 0,000 4,408E-03 0,0189734 ! anaphase GO:0051322 17 7 0,000 4,408E-03 0,01893951 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 4,408E-03 0,01890575 ! axonal fasciculation GO:0007413 18 7 0,000 4,408E-03 0,01887211 ! negative regulation of nuclear division GO:0051784 14 7 0,000 4,408E-03 0,01883859 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 4,408E-03 0,01880519 ! peptidyl-threonine modification GO:0018210 25 7 0,000 4,408E-03 0,01877191 ! diuresis GO:0030146 12 7 0,000 4,408E-03 0,01873874 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 4,408E-03 0,01870569 ! thiamin metabolic process GO:0006772 7 7 0,000 4,408E-03 0,01867276 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,408E-03 0,01863994 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 4,408E-03 0,01860724 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 4,408E-03 0,01857466 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 4,408E-03 0,01854218 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,408E-03 0,01850982 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,408E-03 0,01847758 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,408E-03 0,01844544 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 4,408E-03 0,01841342 ! dopamine biosynthetic process GO:0042416 18 7 0,000 4,408E-03 0,0183815 ! glycolipid catabolic process GO:0019377 15 7 0,000 4,408E-03 0,0183497 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 4,408E-03 0,01831801 ! lymph node development GO:0048535 10 7 0,000 4,408E-03 0,01828643 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 4,408E-03 0,01825495 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,408E-03 0,01822359 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 4,408E-03 0,01819233 ! endosome to lysosome transport GO:0008333 11 7 0,000 4,408E-03 0,01816118 ! protein modification by small protein removal GO:0070646 16 7 0,000 4,408E-03 0,01813013 ! adult feeding behavior GO:0008343 9 7 0,000 4,408E-03 0,01809919 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 4,408E-03 0,01806836 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 4,408E-03 0,01803763 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,408E-03 0,01800701 ! muscle adaptation GO:0043500 14 7 0,000 4,408E-03 0,01797649 ! embryonic heart tube development GO:0035050 10 7 0,000 4,408E-03 0,01794607 ! retina homeostasis GO:0001895 12 7 0,000 4,408E-03 0,01791576 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 4,408E-03 0,01788554 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 4,408E-03 0,01785543 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 4,408E-03 0,01782543 ! protein prenylation GO:0018342 18 7 0,000 4,408E-03 0,01779552 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 4,408E-03 0,01776571 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 4,408E-03 0,017736 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,408E-03 0,01770639 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 5,036E-03 0,02019611 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 5,036E-03 0,02016251 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 5,036E-03 0,02012902 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 5,036E-03 0,02009564 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 5,036E-03 0,02006237 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 5,036E-03 0,0200292 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 5,036E-03 0,01999615 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 5,036E-03 0,01996321 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 5,036E-03 0,01993038 ! neutral lipid catabolic process GO:0046461 13 8 0,000 5,036E-03 0,01989765 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 5,036E-03 0,01986503 ! meiotic prophase I GO:0007128 13 8 0,000 5,036E-03 0,01983252 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 5,036E-03 0,01980011 ! oligopeptide transport GO:0006857 15 8 0,000 5,036E-03 0,01976781 ! UTP metabolic process GO:0046051 8 8 0,000 5,036E-03 0,01973562 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 5,036E-03 0,01970353 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 5,036E-03 0,01967154 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 5,036E-03 0,01963966 ! macrophage chemotaxis GO:0048246 12 8 0,000 5,036E-03 0,01960788 ! succinate metabolic process GO:0006105 14 8 0,000 5,036E-03 0,0195762 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,036E-03 0,01954463 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 5,036E-03 0,01951315 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 5,036E-03 0,01948178 ! T-helper 1 type immune response GO:0042088 12 8 0,000 5,036E-03 0,01945051 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 5,036E-03 0,01941934 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 5,036E-03 0,01938827 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,036E-03 0,0193573 ! ganglioside metabolic process GO:0001573 19 8 0,000 5,036E-03 0,01932643 ! reflex GO:0060004 16 8 0,000 5,036E-03 0,01929565 ! negative regulation of endocytosis GO:0045806 11 8 0,000 5,036E-03 0,01926497 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 5,036E-03 0,01923439 ! endothelial cell differentiation GO:0045446 17 8 0,000 5,036E-03 0,01920391 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 5,036E-03 0,01917353 ! glycerolipid catabolic process GO:0046503 13 8 0,000 5,036E-03 0,01914324 ! hemoglobin metabolic process GO:0020027 13 8 0,000 5,036E-03 0,01911304 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 5,036E-03 0,01908294 ! pigment granule organization GO:0048753 16 8 0,000 5,036E-03 0,01905294 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 5,036E-03 0,01902303 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 5,036E-03 0,01899321 ! astrocyte differentiation GO:0048708 18 8 0,000 5,036E-03 0,01896349 ! histidine metabolic process GO:0006547 16 8 0,000 5,036E-03 0,01893386 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 5,036E-03 0,01890432 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 5,036E-03 0,01887487 ! glycine catabolic process GO:0006546 13 8 0,000 5,036E-03 0,01884552 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 5,036E-03 0,01881626 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 5,036E-03 0,01878708 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 5,036E-03 0,018758 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 5,036E-03 0,01872901 ! regulation of pigmentation during development GO:0048070 24 8 0,000 5,036E-03 0,01870011 ! melanin metabolic process GO:0006582 15 8 0,000 5,036E-03 0,01867129 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 5,036E-03 0,01864257 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,036E-03 0,01861393 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 5,036E-03 0,01858538 ! macrophage activation GO:0042116 12 8 0,000 5,036E-03 0,01855692 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 5,036E-03 0,01852855 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 5,036E-03 0,01850026 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 5,036E-03 0,01847206 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 5,036E-03 0,01844394 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 5,036E-03 0,01841591 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 5,036E-03 0,01838796 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,036E-03 0,0183601 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 5,036E-03 0,01833233 ! osteoblast development GO:0002076 16 8 0,000 5,036E-03 0,01830464 ! positive regulation of vasodilation GO:0045909 13 8 0,000 5,036E-03 0,01827703 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 5,036E-03 0,0182495 ! negative regulation of translational initiation GO:0045947 10 8 0,000 5,036E-03 0,01822206 ! Schwann cell differentiation GO:0014037 19 8 0,000 5,036E-03 0,0181947 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 5,036E-03 0,01816742 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 5,036E-03 0,01814022 ! response to UV-B GO:0010224 16 8 0,000 5,036E-03 0,01811311 ! protein targeting to vacuole GO:0006623 12 8 0,000 5,036E-03 0,01808607 ! protein retention in ER lumen GO:0006621 14 8 0,000 5,036E-03 0,01805912 ! intermediate filament organization GO:0045109 12 8 0,000 5,036E-03 0,01803224 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 5,036E-03 0,01800545 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 5,036E-03 0,01797874 ! cellular extravasation GO:0045123 12 8 0,000 5,036E-03 0,0179521 ! cardiac muscle cell development GO:0055013 13 8 0,000 5,036E-03 0,01792555 ! regulation of circadian rhythm GO:0042752 16 8 0,000 5,036E-03 0,01789907 ! response to antibiotic GO:0046677 11 8 0,000 5,036E-03 0,01787267 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 5,036E-03 0,01784635 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 5,036E-03 0,0178201 ! DNA topological change GO:0006265 12 8 0,000 5,036E-03 0,01779393 ! response to tropane GO:0014073 15 8 0,000 5,036E-03 0,01776784 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 5,036E-03 0,01774183 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 5,036E-03 0,01771589 ! melanosome transport GO:0032402 13 8 0,000 5,036E-03 0,01769003 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 5,036E-03 0,01766424 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 5,036E-03 0,01763853 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 5,036E-03 0,01761289 ! mast cell activation GO:0045576 14 8 0,000 5,036E-03 0,01758733 ! multicellular organismal aging GO:0010259 18 8 0,000 5,036E-03 0,01756184 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 5,036E-03 0,01753642 ! dendrite morphogenesis GO:0048813 13 8 0,000 5,036E-03 0,01751108 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 5,036E-03 0,01748581 ! nucleosome disassembly GO:0006337 14 8 0,000 5,036E-03 0,01746062 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 5,036E-03 0,01743549 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 5,036E-03 0,01741044 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,036E-03 0,01738546 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 5,036E-03 0,01736056 ! establishment of chromosome localization GO:0051303 12 8 0,000 5,036E-03 0,01733572 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 5,036E-03 0,01731096 ! intracellular lipid transport GO:0032365 13 8 0,000 5,036E-03 0,01728626 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 5,036E-03 0,01726164 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,036E-03 0,01723708 ! regulation of macrophage activation GO:0043030 15 8 0,000 5,036E-03 0,0172126 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 5,036E-03 0,01718818 ! positive regulation of epidermis development GO:0045684 13 8 0,000 5,036E-03 0,01716384 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 5,036E-03 0,01713956 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 5,036E-03 0,01711535 ! hormone catabolic process GO:0042447 17 8 0,000 5,036E-03 0,01709121 ! positive regulation of glucose import GO:0046326 8 8 0,000 5,036E-03 0,01706714 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 5,036E-03 0,01704313 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 5,036E-03 0,0170192 ! ATP catabolic process GO:0006200 11 8 0,000 5,036E-03 0,01699533 ! blastocyst growth GO:0001832 19 8 0,000 5,036E-03 0,01697152 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 5,036E-03 0,01694779 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 5,036E-03 0,01692412 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 5,036E-03 0,01690051 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 5,036E-03 0,01687698 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,036E-03 0,0168535 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 5,036E-03 0,0168301 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 5,036E-03 0,01680675 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 5,036E-03 0,01678347 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 5,036E-03 0,01676026 ! amino sugar catabolic process GO:0046348 10 8 0,000 5,036E-03 0,01673711 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 5,036E-03 0,01671403 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 5,036E-03 0,016691 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 5,036E-03 0,01666804 ! behavioral response to nicotine GO:0035095 12 8 0,000 5,036E-03 0,01664515 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,036E-03 0,01662232 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 5,036E-03 0,01659955 ! NAD biosynthetic process GO:0009435 13 8 0,000 5,036E-03 0,01657684 ! regulation of developmental growth GO:0048638 15 9 0,000 5,664E-03 0,0186179 ! axon extension GO:0048675 15 9 0,000 5,664E-03 0,0185925 ! autophagic vacuole formation GO:0000045 15 9 0,000 5,664E-03 0,01856717 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 5,664E-03 0,01854191 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 5,664E-03 0,01851672 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 5,664E-03 0,01849159 ! pentose-phosphate shunt GO:0006098 16 9 0,000 5,664E-03 0,01846654 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 5,664E-03 0,01844155 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 5,664E-03 0,01841663 ! cell proliferation in forebrain GO:0021846 15 9 0,000 5,664E-03 0,01839178 ! phosphate transport GO:0006817 19 9 0,000 5,664E-03 0,01836699 ! reproductive behavior GO:0019098 19 9 0,000 5,664E-03 0,01834227 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 5,664E-03 0,01831761 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 5,664E-03 0,01829303 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 5,664E-03 0,01826851 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 5,664E-03 0,01824405 ! GTP metabolic process GO:0046039 9 9 0,000 5,664E-03 0,01821966 ! RNA methylation GO:0001510 15 9 0,000 5,664E-03 0,01819533 ! elastic fiber assembly GO:0048251 15 9 0,000 5,664E-03 0,01817107 ! induction of positive chemotaxis GO:0050930 15 9 0,000 5,664E-03 0,01814688 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 5,664E-03 0,01812275 ! artery development GO:0060840 24 9 0,000 5,664E-03 0,01809868 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 5,664E-03 0,01807468 ! regulation of glycolysis GO:0006110 21 9 0,000 5,664E-03 0,01805074 ! cerebral cortex cell migration GO:0021795 15 9 0,000 5,664E-03 0,01802686 ! keratinocyte proliferation GO:0043616 14 9 0,000 5,664E-03 0,01800305 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 5,664E-03 0,01797929 ! chemosensory behavior GO:0007635 20 9 0,000 5,664E-03 0,01795561 ! microtubule bundle formation GO:0001578 21 9 0,000 5,664E-03 0,01793198 ! middle ear morphogenesis GO:0042474 14 9 0,000 5,664E-03 0,01790842 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 5,664E-03 0,01788492 ! leukocyte degranulation GO:0043299 16 9 0,000 5,664E-03 0,01786148 ! bile acid and bile salt transport GO:0015721 13 9 0,000 5,664E-03 0,0178381 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 5,664E-03 0,01781478 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 5,664E-03 0,01779152 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 5,664E-03 0,01776833 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 5,664E-03 0,01774519 ! protein targeting to ER GO:0045047 22 9 0,000 5,664E-03 0,01772211 ! ceramide biosynthetic process GO:0046513 19 9 0,000 5,664E-03 0,0176991 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 5,664E-03 0,01767614 ! T cell selection GO:0045058 23 9 0,000 5,664E-03 0,01765325 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 5,664E-03 0,01763041 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 5,664E-03 0,01760763 ! phosphagen metabolic process GO:0006599 12 9 0,000 5,664E-03 0,01758491 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 5,664E-03 0,01756225 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 5,664E-03 0,01753965 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 5,664E-03 0,0175171 ! regulation of type I interferon production GO:0032479 12 9 0,000 5,664E-03 0,01749462 ! mannose metabolic process GO:0006013 13 9 0,000 5,664E-03 0,01747219 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 5,664E-03 0,01744981 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 5,664E-03 0,0174275 ! Rac protein signal transduction GO:0016601 17 9 0,000 5,664E-03 0,01740524 ! receptor clustering GO:0043113 18 9 0,000 5,664E-03 0,01738304 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 5,664E-03 0,0173609 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 5,664E-03 0,01733881 ! ruffle organization GO:0031529 15 9 0,000 5,664E-03 0,01731678 ! retinol metabolic process GO:0042572 18 9 0,000 5,664E-03 0,0172948 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 5,664E-03 0,01727288 ! behavioral fear response GO:0001662 22 9 0,000 5,664E-03 0,01725102 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 5,664E-03 0,01722921 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 5,664E-03 0,01720746 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 5,664E-03 0,01718576 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 5,664E-03 0,01716411 ! oligodendrocyte development GO:0014003 10 9 0,000 5,664E-03 0,01714252 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 5,664E-03 0,01712099 ! segment specification GO:0007379 13 9 0,000 5,664E-03 0,0170995 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 5,664E-03 0,01707808 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 5,664E-03 0,0170567 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 5,664E-03 0,01703538 ! response to amine stimulus GO:0014075 13 9 0,000 5,664E-03 0,01701411 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 5,664E-03 0,0169929 ! erythrocyte development GO:0048821 15 9 0,000 5,664E-03 0,01697174 ! gas homeostasis GO:0033483 16 9 0,000 5,664E-03 0,01695063 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 5,664E-03 0,01692957 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 5,664E-03 0,01690857 ! renal water homeostasis GO:0003091 14 9 0,000 5,664E-03 0,01688762 ! postreplication repair GO:0006301 22 9 0,000 5,664E-03 0,01686671 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 5,664E-03 0,01684587 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 5,664E-03 0,01682507 ! icosanoid secretion GO:0032309 15 9 0,000 5,664E-03 0,01680432 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 5,664E-03 0,01678363 ! cerebellum morphogenesis GO:0021587 14 9 0,000 5,664E-03 0,01676298 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 5,664E-03 0,01674239 ! regulation of cell division GO:0051302 15 9 0,000 5,664E-03 0,01672185 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 5,664E-03 0,01670135 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 5,664E-03 0,01668091 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 5,664E-03 0,01666052 ! sterol catabolic process GO:0016127 11 9 0,000 5,664E-03 0,01664018 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 5,664E-03 0,01661988 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 5,664E-03 0,01659964 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 5,664E-03 0,01657945 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 5,664E-03 0,0165593 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 5,664E-03 0,01653921 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 5,664E-03 0,01651916 ! musculoskeletal movement GO:0050881 14 9 0,000 5,664E-03 0,01649916 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 5,664E-03 0,01647921 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 5,664E-03 0,01645931 ! regulation of synaptogenesis GO:0051963 15 9 0,000 5,664E-03 0,01643945 ! purine base metabolic process GO:0006144 21 9 0,000 5,664E-03 0,01641965 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 5,664E-03 0,01639989 ! pigment granule transport GO:0051904 17 9 0,000 5,664E-03 0,01638017 ! regulation of fibrinolysis GO:0051917 16 9 0,000 5,664E-03 0,01636051 ! regulation of telomere maintenance GO:0032204 14 9 0,000 5,664E-03 0,01634089 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 5,664E-03 0,01632132 ! regulation of muscle adaptation GO:0043502 14 9 0,000 5,664E-03 0,0163018 ! regulation of amino acid transport GO:0051955 11 9 0,000 5,664E-03 0,01628232 ! mitochondrion localization GO:0051646 15 9 0,000 5,664E-03 0,01626289 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 6,292E-03 0,01804295 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 6,292E-03 0,01802148 ! negative regulation of blood pressure GO:0045776 26 10 0,000 6,292E-03 0,01800005 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 6,292E-03 0,01797867 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 6,292E-03 0,01795734 ! regulation of phosphatase activity GO:0010921 28 10 0,000 6,292E-03 0,01793607 ! synapsis GO:0007129 13 10 0,000 6,292E-03 0,01791484 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 6,292E-03 0,01789366 ! N-glycan processing GO:0006491 20 10 0,000 6,292E-03 0,01787254 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 6,292E-03 0,01785146 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 6,292E-03 0,01783043 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 6,292E-03 0,01780946 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 6,292E-03 0,01778853 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 6,292E-03 0,01776765 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 6,292E-03 0,01774682 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 6,292E-03 0,01772604 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 6,292E-03 0,01770531 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 6,292E-03 0,01768463 ! androgen metabolic process GO:0008209 17 10 0,000 6,292E-03 0,01766399 ! phospholipid efflux GO:0033700 16 10 0,000 6,292E-03 0,0176434 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 6,292E-03 0,01762286 ! positive regulation of heart contraction GO:0045823 16 10 0,000 6,292E-03 0,01760237 ! lung alveolus development GO:0048286 26 10 0,000 6,292E-03 0,01758193 ! pathogenesis GO:0009405 13 10 0,000 6,292E-03 0,01756153 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,292E-03 0,01754118 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 6,292E-03 0,01752088 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 6,292E-03 0,01750062 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 6,292E-03 0,01748041 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 6,292E-03 0,01746025 ! endoderm development GO:0007492 16 10 0,000 6,292E-03 0,01744014 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 6,292E-03 0,01742007 ! arginine catabolic process GO:0006527 13 10 0,000 6,292E-03 0,01740005 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 6,292E-03 0,01738007 ! proline metabolic process GO:0006560 13 10 0,000 6,292E-03 0,01736014 ! glucan biosynthetic process GO:0009250 14 10 0,000 6,292E-03 0,01734025 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 6,292E-03 0,01732041 ! polyamine biosynthetic process GO:0006596 12 10 0,000 6,292E-03 0,01730062 ! V(D)J recombination GO:0033151 28 10 0,000 6,292E-03 0,01728087 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,292E-03 0,01726116 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 6,292E-03 0,0172415 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 6,292E-03 0,01722189 ! B cell proliferation GO:0042100 18 10 0,000 6,292E-03 0,01720232 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 6,292E-03 0,01718279 ! regulation of sodium ion transport GO:0002028 21 10 0,000 6,292E-03 0,01716331 ! multicellular organism growth GO:0035264 18 10 0,000 6,292E-03 0,01714387 ! phagocytosis, engulfment GO:0006911 28 10 0,000 6,292E-03 0,01712448 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 6,292E-03 0,01710513 ! epithelial cell development GO:0002064 20 10 0,000 6,292E-03 0,01708582 ! lens development in camera-type eye GO:0002088 16 10 0,000 6,292E-03 0,01706656 ! retinoic acid metabolic process GO:0042573 14 10 0,000 6,292E-03 0,01704734 ! macroautophagy GO:0016236 17 10 0,000 6,292E-03 0,01702817 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 6,292E-03 0,01700903 ! positive regulation of translational initiation GO:0045948 11 10 0,000 6,292E-03 0,01698994 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 6,292E-03 0,0169709 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 6,292E-03 0,01695189 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 6,292E-03 0,01693293 ! copper ion homeostasis GO:0055070 13 10 0,000 6,292E-03 0,01691401 ! regulation of bone resorption GO:0045124 25 10 0,000 6,292E-03 0,01689513 ! regulation of gliogenesis GO:0014013 23 10 0,000 6,292E-03 0,0168763 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 6,292E-03 0,0168575 ! alpha-beta T cell activation GO:0046631 23 10 0,000 6,292E-03 0,01683875 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 6,292E-03 0,01682004 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 6,292E-03 0,01680138 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 6,292E-03 0,01678275 ! blastoderm segmentation GO:0007350 18 10 0,000 6,292E-03 0,01676416 ! response to dsRNA GO:0043331 20 10 0,000 6,292E-03 0,01674562 ! DNA ligation GO:0006266 19 10 0,000 6,292E-03 0,01672712 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,292E-03 0,01670865 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 6,292E-03 0,01669023 ! melanosome localization GO:0032400 16 10 0,000 6,292E-03 0,01667185 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 6,292E-03 0,01665351 ! regulation of B cell differentiation GO:0045577 19 10 0,000 6,292E-03 0,01663521 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 6,292E-03 0,01661695 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 6,292E-03 0,01659873 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 6,292E-03 0,01658055 ! mRNA cleavage GO:0006379 17 10 0,000 6,292E-03 0,01656241 ! protein sumoylation GO:0016925 15 10 0,000 6,292E-03 0,01654431 ! hindbrain morphogenesis GO:0021575 19 10 0,000 6,292E-03 0,01652624 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,292E-03 0,01650822 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 6,292E-03 0,01649024 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 6,292E-03 0,0164723 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 6,292E-03 0,01645439 ! salivary gland development GO:0007431 27 10 0,000 6,292E-03 0,01643652 ! prophase GO:0051324 15 10 0,000 6,292E-03 0,0164187 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,292E-03 0,01640091 ! apical protein localization GO:0045176 15 10 0,000 6,292E-03 0,01638316 ! ubiquinone metabolic process GO:0006743 15 10 0,000 6,292E-03 0,01636545 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 6,292E-03 0,01634777 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 6,292E-03 0,01633014 ! midbrain development GO:0030901 13 10 0,000 6,292E-03 0,01631254 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,292E-03 0,01629498 ! methionine biosynthetic process GO:0009086 19 10 0,000 6,292E-03 0,01627746 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 6,292E-03 0,01625998 ! quaternary ammonium group transport GO:0015697 21 10 0,000 6,292E-03 0,01624253 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 6,292E-03 0,01622512 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 6,292E-03 0,01620775 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 6,292E-03 0,01619042 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 6,292E-03 0,01617312 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 6,292E-03 0,01615586 ! oocyte development GO:0048599 17 10 0,000 6,292E-03 0,01613863 ! establishment of pigment granule localization GO:0051905 18 10 0,000 6,292E-03 0,01612145 ! blastocyst formation GO:0001825 17 10 0,000 6,292E-03 0,0161043 ! cerebellar cortex development GO:0021695 15 10 0,000 6,292E-03 0,01608718 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 6,292E-03 0,01607011 ! activation of innate immune response GO:0002218 12 10 0,000 6,292E-03 0,01605306 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 6,292E-03 0,01603606 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 6,292E-03 0,01601909 ! response to nicotine GO:0035094 20 10 0,000 6,292E-03 0,01600216 ! establishment of cell polarity GO:0030010 16 10 0,000 6,292E-03 0,01598526 ! negative regulation of immune effector process GO:0002698 20 10 0,000 6,292E-03 0,0159684 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 6,292E-03 0,01595157 ! localization within membrane GO:0051668 20 10 0,000 6,292E-03 0,01593478 ! negative regulation of muscle development GO:0048635 20 11 0,000 6,919E-03 0,0175046 ! respiratory burst GO:0045730 17 11 0,000 6,919E-03 0,01748621 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 6,919E-03 0,01746786 ! neuron fate specification GO:0048665 17 11 0,000 6,919E-03 0,01744955 ! telencephalon cell migration GO:0022029 20 11 0,000 6,919E-03 0,01743128 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 6,919E-03 0,01741304 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 6,919E-03 0,01739485 ! thyroid gland development GO:0030878 26 11 0,000 6,919E-03 0,01737669 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 6,919E-03 0,01735857 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 6,919E-03 0,01734049 ! Golgi vesicle budding GO:0048194 22 11 0,000 6,919E-03 0,01732245 ! response to pain GO:0048265 24 11 0,000 6,919E-03 0,01730444 ! detection of mechanical stimulus GO:0050982 22 11 0,000 6,919E-03 0,01728647 ! T cell proliferation GO:0042098 26 11 0,000 6,919E-03 0,01726854 ! blood vessel remodeling GO:0001974 29 11 0,000 6,919E-03 0,01725064 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 6,919E-03 0,01723278 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 6,919E-03 0,01721496 ! bone resorption GO:0045453 16 11 0,000 6,919E-03 0,01719718 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 6,919E-03 0,01717943 ! ventral spinal cord development GO:0021517 21 11 0,000 6,919E-03 0,01716172 ! negative regulation of proteolysis GO:0045861 25 11 0,000 6,919E-03 0,01714405 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 6,919E-03 0,01712641 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 6,919E-03 0,01710881 ! melanocyte differentiation GO:0030318 21 11 0,000 6,919E-03 0,01709124 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 6,919E-03 0,01707371 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 6,919E-03 0,01705622 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 6,919E-03 0,01703876 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 6,919E-03 0,01702134 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 6,919E-03 0,01700395 ! lipid digestion GO:0044241 18 11 0,000 6,919E-03 0,0169866 ! substrate-bound cell migration GO:0006929 13 11 0,000 6,919E-03 0,01696929 ! UV protection GO:0009650 19 11 0,000 6,919E-03 0,01695201 ! adult heart development GO:0007512 14 11 0,000 6,919E-03 0,01693476 ! chondrocyte differentiation GO:0002062 24 11 0,000 6,919E-03 0,01691755 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 6,919E-03 0,01690038 ! temperature homeostasis GO:0001659 17 11 0,000 6,919E-03 0,01688324 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 6,919E-03 0,01686613 ! negative regulation of ossification GO:0030279 26 11 0,000 6,919E-03 0,01684906 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 6,919E-03 0,01683202 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 6,919E-03 0,01681502 ! regulation of organ growth GO:0046620 13 11 0,000 6,919E-03 0,01679805 ! pigment granule localization GO:0051875 20 11 0,000 6,919E-03 0,01678112 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 6,919E-03 0,01676422 ! vasoconstriction GO:0042310 18 11 0,000 6,919E-03 0,01674735 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 6,919E-03 0,01673052 ! embryonic axis specification GO:0000578 18 11 0,000 6,919E-03 0,01671373 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 6,919E-03 0,01669696 ! snRNA metabolic process GO:0016073 24 11 0,000 6,919E-03 0,01668023 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 6,919E-03 0,01666353 ! nitric oxide metabolic process GO:0046209 15 11 0,000 6,919E-03 0,01664687 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 6,919E-03 0,01663024 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 6,919E-03 0,01661364 ! zymogen activation GO:0031638 15 11 0,000 6,919E-03 0,01659708 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 6,919E-03 0,01658055 ! neuroblast proliferation GO:0007405 24 11 0,000 6,919E-03 0,01656405 ! nucleosome positioning GO:0016584 15 11 0,000 6,919E-03 0,01654758 ! regulation of isotype switching GO:0045191 22 11 0,000 6,919E-03 0,01653115 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 6,919E-03 0,01651475 ! glutathione biosynthetic process GO:0006750 13 11 0,000 6,919E-03 0,01649838 ! regulation of leukocyte migration GO:0002685 26 11 0,000 6,919E-03 0,01648205 ! acid secretion GO:0046717 18 11 0,000 6,919E-03 0,01646575 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 6,919E-03 0,01644948 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 6,919E-03 0,01643324 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 6,919E-03 0,01641703 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 6,919E-03 0,01640086 ! oocyte differentiation GO:0009994 18 11 0,000 6,919E-03 0,01638471 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 6,919E-03 0,0163686 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 6,919E-03 0,01635252 ! cholesterol efflux GO:0033344 19 11 0,000 6,919E-03 0,01633648 ! anterior/posterior axis specification GO:0009948 18 11 0,000 6,919E-03 0,01632046 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 6,919E-03 0,01630448 ! negative regulation of glucose import GO:0046325 17 11 0,000 6,919E-03 0,01628852 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 6,919E-03 0,0162726 ! embryonic gut development GO:0048566 15 11 0,000 6,919E-03 0,01625671 ! regulation of organic acid transport GO:0032890 18 11 0,000 6,919E-03 0,01624085 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 6,919E-03 0,01622502 ! cardiac cell differentiation GO:0035051 31 11 0,000 6,919E-03 0,01620922 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 6,919E-03 0,01619345 ! defense response to fungus GO:0050832 13 11 0,000 6,919E-03 0,01617772 ! developmental induction GO:0031128 19 11 0,000 6,919E-03 0,01616201 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 6,919E-03 0,01614633 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 6,919E-03 0,01613069 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 6,919E-03 0,01611507 ! sequestering of metal ion GO:0051238 14 11 0,000 6,919E-03 0,01609949 ! lamellipodium assembly GO:0030032 20 11 0,000 6,919E-03 0,01608393 ! regulation of embryonic development GO:0045995 27 11 0,000 6,919E-03 0,01606841 ! nucleus localization GO:0051647 19 11 0,000 6,919E-03 0,01605291 ! regulation of synapse organization GO:0050807 17 11 0,000 6,919E-03 0,01603745 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 7,546E-03 0,01747334 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 7,546E-03 0,01745654 ! positive regulation of blood pressure GO:0045777 17 12 0,000 7,546E-03 0,01743977 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 7,546E-03 0,01742303 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 7,546E-03 0,01740633 ! virus-host interaction GO:0019048 29 12 0,000 7,546E-03 0,01738965 ! regulation of B cell proliferation GO:0030888 20 12 0,000 7,546E-03 0,01737301 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 7,546E-03 0,0173564 ! cartilage condensation GO:0001502 20 12 0,000 7,546E-03 0,01733983 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 7,546E-03 0,01732328 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 7,546E-03 0,01730677 ! protein complex disassembly GO:0043241 27 12 0,000 7,546E-03 0,01729028 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 7,546E-03 0,01727383 ! regulation of cell projection assembly GO:0060491 30 12 0,000 7,546E-03 0,01725741 ! hippocampus development GO:0021766 26 12 0,000 7,546E-03 0,01724102 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 7,546E-03 0,01722467 ! cytokine biosynthetic process GO:0042089 21 12 0,000 7,546E-03 0,01720834 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 7,546E-03 0,01719204 ! positive regulation of cell growth GO:0030307 22 12 0,000 7,546E-03 0,01717578 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 7,546E-03 0,01715955 ! regulation of exit from mitosis GO:0007096 17 12 0,000 7,546E-03 0,01714334 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 7,546E-03 0,01712717 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 7,546E-03 0,01711103 ! drug transport GO:0015893 16 12 0,000 7,546E-03 0,01709491 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 7,546E-03 0,01707883 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 7,546E-03 0,01706278 ! tyrosine metabolic process GO:0006570 16 12 0,000 7,546E-03 0,01704676 ! polyamine metabolic process GO:0006595 17 12 0,000 7,546E-03 0,01703077 ! focal adhesion formation GO:0048041 35 12 0,000 7,546E-03 0,01701481 ! mitotic spindle organization GO:0007052 21 12 0,000 7,546E-03 0,01699888 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 7,546E-03 0,01698297 ! forebrain cell migration GO:0021885 21 12 0,000 7,546E-03 0,0169671 ! asymmetric protein localization GO:0008105 20 12 0,000 7,546E-03 0,01695126 ! membrane protein proteolysis GO:0033619 25 12 0,000 7,546E-03 0,01693545 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 7,546E-03 0,01691966 ! entry into host cell GO:0030260 32 12 0,000 7,546E-03 0,01690391 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 7,546E-03 0,01688819 ! monoamine transport GO:0015844 18 12 0,000 7,546E-03 0,01687249 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 7,546E-03 0,01685682 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 7,546E-03 0,01684119 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 7,546E-03 0,01682558 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 7,546E-03 0,01681 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 7,546E-03 0,01679445 ! protein targeting to peroxisome GO:0006625 23 12 0,000 7,546E-03 0,01677893 ! protein homotetramerization GO:0051289 21 12 0,000 7,546E-03 0,01676343 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 7,546E-03 0,01674797 ! regulation of phagocytosis GO:0050764 16 12 0,000 7,546E-03 0,01673253 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 7,546E-03 0,01671713 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 7,546E-03 0,01670175 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 7,546E-03 0,0166864 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 7,546E-03 0,01667107 ! cranial nerve development GO:0021545 20 12 0,000 7,546E-03 0,01665578 ! fucose catabolic process GO:0019317 22 12 0,000 7,546E-03 0,01664051 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 7,546E-03 0,01662527 ! histone acetylation GO:0016573 26 12 0,000 7,546E-03 0,01661006 ! histone methylation GO:0016571 26 12 0,000 7,546E-03 0,01659488 ! mRNA polyadenylation GO:0006378 23 12 0,000 7,546E-03 0,01657973 ! autonomic nervous system development GO:0048483 24 12 0,000 7,546E-03 0,0165646 ! gland morphogenesis GO:0022612 29 12 0,000 7,546E-03 0,0165495 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 7,546E-03 0,01653443 ! peptidyl-lysine modification GO:0018205 21 12 0,000 7,546E-03 0,01651938 ! T cell homeostasis GO:0043029 25 12 0,000 7,546E-03 0,01650436 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 7,546E-03 0,01648937 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 7,546E-03 0,01647441 ! spleen development GO:0048536 22 12 0,000 7,546E-03 0,01645947 ! digestive tract morphogenesis GO:0048546 26 12 0,000 7,546E-03 0,01644456 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 7,546E-03 0,01642968 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 7,546E-03 0,01641483 ! regulation of RNA splicing GO:0043484 20 12 0,000 7,546E-03 0,0164 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 7,546E-03 0,0163852 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 7,546E-03 0,01637042 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 7,546E-03 0,01635567 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 7,546E-03 0,01634095 ! response to cold GO:0009409 17 12 0,000 7,546E-03 0,01632626 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 7,546E-03 0,01631159 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 7,546E-03 0,01629695 ! cGMP metabolic process GO:0046068 18 13 0,000 8,172E-03 0,01763393 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 8,172E-03 0,01761812 ! regulation of chemokine production GO:0032642 18 13 0,000 8,172E-03 0,01760235 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 8,172E-03 0,01758661 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 8,172E-03 0,01757089 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 8,172E-03 0,0175552 ! lipid localization GO:0010876 28 13 0,000 8,172E-03 0,01753954 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 8,172E-03 0,01752391 ! organelle fusion GO:0048284 32 13 0,000 8,172E-03 0,01750831 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 8,172E-03 0,01749273 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 8,172E-03 0,01747718 ! pseudouridine synthesis GO:0001522 17 13 0,000 8,172E-03 0,01746166 ! endocrine pancreas development GO:0031018 22 13 0,000 8,172E-03 0,01744616 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 8,172E-03 0,0174307 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 8,172E-03 0,01741526 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 8,172E-03 0,01739985 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 8,172E-03 0,01738446 ! methionine metabolic process GO:0006555 27 13 0,000 8,172E-03 0,0173691 ! plasma membrane organization GO:0007009 24 13 0,000 8,172E-03 0,01735377 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 8,172E-03 0,01733847 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 8,172E-03 0,0173232 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 8,172E-03 0,01730795 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 8,172E-03 0,01729272 ! cell-cell junction assembly GO:0007043 27 13 0,000 8,172E-03 0,01727753 ! response to X-ray GO:0010165 25 13 0,000 8,172E-03 0,01726236 ! cytokine metabolic process GO:0042107 22 13 0,000 8,172E-03 0,01724722 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 8,172E-03 0,0172321 ! exocrine system development GO:0035272 32 13 0,000 8,172E-03 0,01721701 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 8,172E-03 0,01720195 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 8,172E-03 0,01718691 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 8,172E-03 0,0171719 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 8,172E-03 0,01715692 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 8,172E-03 0,01714196 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 8,172E-03 0,01712703 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 8,172E-03 0,01711212 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 8,172E-03 0,01709724 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 8,172E-03 0,01708239 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 8,172E-03 0,01706756 ! regulation of cellular pH GO:0030641 22 13 0,000 8,172E-03 0,01705276 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 8,172E-03 0,01703798 ! ribosome assembly GO:0042255 17 13 0,000 8,172E-03 0,01702323 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 8,172E-03 0,0170085 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 8,172E-03 0,0169938 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 8,172E-03 0,01697912 ! chromatin silencing GO:0006342 26 13 0,000 8,172E-03 0,01696448 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 8,172E-03 0,01694985 ! regulation of epidermis development GO:0045682 19 13 0,000 8,172E-03 0,01693525 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 8,172E-03 0,01692068 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 8,172E-03 0,01690613 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 8,172E-03 0,0168916 ! regulation of mRNA stability GO:0043488 31 13 0,000 8,172E-03 0,0168771 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 8,172E-03 0,01686263 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 8,172E-03 0,01684818 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 8,172E-03 0,01683376 ! mRNA 3'-end processing GO:0031124 24 13 0,000 8,172E-03 0,01681936 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 8,172E-03 0,01680498 ! embryonic placenta development GO:0001892 23 13 0,000 8,172E-03 0,01679063 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 8,172E-03 0,0167763 ! insulin secretion GO:0030073 23 13 0,000 8,172E-03 0,016762 ! actin filament polymerization GO:0030041 24 13 0,000 8,172E-03 0,01674772 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 8,172E-03 0,01673347 ! acrosome reaction GO:0007340 18 13 0,000 8,172E-03 0,01671924 ! rRNA transcription GO:0009303 25 14 0,000 8,798E-03 0,01798467 ! lactation GO:0007595 26 14 0,000 8,798E-03 0,0179694 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 8,798E-03 0,01795416 ! reproductive cellular process GO:0048610 20 14 0,000 8,798E-03 0,01793894 ! tRNA modification GO:0006400 20 14 0,000 8,798E-03 0,01792375 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 8,798E-03 0,01790859 ! regulation of S phase GO:0033261 23 14 0,000 8,798E-03 0,01789345 ! water transport GO:0006833 21 14 0,000 8,798E-03 0,01787834 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 8,798E-03 0,01786325 ! non-recombinational repair GO:0000726 25 14 0,000 8,798E-03 0,01784819 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 8,798E-03 0,01783315 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 8,798E-03 0,01781814 ! retina development in camera-type eye GO:0060041 27 14 0,000 8,798E-03 0,01780316 ! hair follicle morphogenesis GO:0031069 26 14 0,000 8,798E-03 0,0177882 ! RNA polyadenylation GO:0043631 30 14 0,000 8,798E-03 0,01777326 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 8,798E-03 0,01775835 ! palate development GO:0060021 31 14 0,000 8,798E-03 0,01774346 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 8,798E-03 0,0177286 ! regulated secretory pathway GO:0045055 23 14 0,000 8,798E-03 0,01771377 ! regulation of mRNA processing GO:0050684 24 14 0,000 8,798E-03 0,01769896 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 8,798E-03 0,01768417 ! arginine metabolic process GO:0006525 17 14 0,000 8,798E-03 0,01766941 ! regulation of heart rate GO:0002027 24 14 0,000 8,798E-03 0,01765467 ! organic alcohol transport GO:0015850 29 14 0,000 8,798E-03 0,01763996 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 8,798E-03 0,01762527 ! negative regulation of caspase activity GO:0043154 22 14 0,000 8,798E-03 0,01761061 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 8,798E-03 0,01759597 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 8,798E-03 0,01758136 ! neutral amino acid transport GO:0015804 26 14 0,000 8,798E-03 0,01756677 ! L-amino acid transport GO:0015807 30 14 0,000 8,798E-03 0,0175522 ! bone mineralization GO:0030282 17 14 0,000 8,798E-03 0,01753766 ! stem cell development GO:0048864 43 14 0,000 8,798E-03 0,01752314 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 8,798E-03 0,01750865 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 8,798E-03 0,01749418 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 8,798E-03 0,01747973 ! cerebellum development GO:0021549 21 14 0,000 8,798E-03 0,01746531 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 8,798E-03 0,01745091 ! negative regulation of protein secretion GO:0050709 28 14 0,000 8,798E-03 0,01743653 ! response to gamma radiation GO:0010332 28 14 0,000 8,798E-03 0,01742218 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 8,798E-03 0,01740786 ! cofactor transport GO:0051181 26 14 0,000 8,798E-03 0,01739355 ! NADP metabolic process GO:0006739 24 14 0,000 8,798E-03 0,01737927 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 8,798E-03 0,01736501 ! protein-chromophore linkage GO:0018298 19 14 0,000 8,798E-03 0,01735078 ! intestinal absorption GO:0050892 25 14 0,000 8,798E-03 0,01733657 ! cAMP biosynthetic process GO:0006171 23 14 0,000 8,798E-03 0,01732238 ! oxygen transport GO:0015671 21 14 0,000 8,798E-03 0,01730822 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 8,798E-03 0,01729408 ! male genitalia development GO:0030539 24 14 0,000 8,798E-03 0,01727996 ! regulation of RNA stability GO:0043487 32 14 0,000 8,798E-03 0,01726587 ! regulation of axon extension GO:0030516 37 14 0,000 8,798E-03 0,0172518 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 8,798E-03 0,01723775 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 8,798E-03 0,01722372 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 9,424E-03 0,01843348 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 9,424E-03 0,0184185 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 9,424E-03 0,01840355 ! superoxide anion generation GO:0042554 20 15 0,000 9,424E-03 0,01838863 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 9,424E-03 0,01837373 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 9,424E-03 0,01835885 ! phospholipid catabolic process GO:0009395 22 15 0,000 9,424E-03 0,018344 ! copper ion transport GO:0006825 20 15 0,000 9,424E-03 0,01832917 ! heterophilic cell adhesion GO:0007157 39 15 0,000 9,424E-03 0,01831436 ! cardiac muscle contraction GO:0060048 26 15 0,000 9,424E-03 0,01829958 ! sulfate transport GO:0008272 23 15 0,000 9,424E-03 0,01828482 ! response to cAMP GO:0051591 22 15 0,000 9,424E-03 0,01827009 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 9,424E-03 0,01825538 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 9,424E-03 0,01824069 ! ciliary or flagellar motility GO:0001539 20 15 0,000 9,424E-03 0,01822603 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 9,424E-03 0,01821139 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 9,424E-03 0,01819677 ! response to hexose stimulus GO:0009746 22 15 0,000 9,424E-03 0,01818218 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 9,424E-03 0,01816761 ! glycoprotein catabolic process GO:0006516 26 15 0,000 9,424E-03 0,01815307 ! pituitary gland development GO:0021983 29 15 0,000 9,424E-03 0,01813854 ! vesicle coating GO:0006901 33 15 0,000 9,424E-03 0,01812404 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 9,424E-03 0,01810957 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 9,424E-03 0,01809511 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 9,424E-03 0,01808068 ! regulation of exocytosis GO:0017157 22 15 0,000 9,424E-03 0,01806628 ! G1/S transition checkpoint GO:0031575 40 15 0,000 9,424E-03 0,01805189 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 9,424E-03 0,01803753 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 9,424E-03 0,01802319 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 9,424E-03 0,01800888 ! regulation of vasodilation GO:0042312 26 15 0,000 9,424E-03 0,01799459 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 9,424E-03 0,01798032 ! histone deacetylation GO:0016575 20 15 0,000 9,424E-03 0,01796607 ! mRNA splice site selection GO:0006376 38 15 0,000 9,424E-03 0,01795184 ! tissue regeneration GO:0042246 26 15 0,000 9,424E-03 0,01793764 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 9,424E-03 0,01792346 ! water homeostasis GO:0030104 27 15 0,000 9,424E-03 0,0179093 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 9,424E-03 0,01789517 ! muscle maintenance GO:0046716 26 15 0,000 9,424E-03 0,01788106 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 9,424E-03 0,01786696 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 9,424E-03 0,0178529 ! regulation of ATPase activity GO:0043462 21 15 0,000 9,424E-03 0,01783885 ! dopamine metabolic process GO:0042417 35 15 0,000 9,424E-03 0,01782483 ! heme biosynthetic process GO:0006783 29 15 0,000 9,424E-03 0,01781082 ! cell killing GO:0001906 29 15 0,000 9,424E-03 0,01779684 ! lymphocyte homeostasis GO:0002260 30 15 0,000 9,424E-03 0,01778289 ! detection of bacterium GO:0016045 18 15 0,000 9,424E-03 0,01776895 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 9,424E-03 0,01775503 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 9,424E-03 0,01774114 ! L-fucose metabolic process GO:0042354 30 15 0,000 9,424E-03 0,01772727 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 9,424E-03 0,01771342 ! peptide hormone processing GO:0016486 23 15 0,000 9,424E-03 0,01769959 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01004884 0,01885921 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01004884 0,01884451 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01004884 0,01882983 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01004884 0,01881518 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01004884 0,01880055 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01004884 0,01878594 ! bone remodeling GO:0046849 27 16 0,000 0,01004884 0,01877135 ! filopodium assembly GO:0046847 32 16 0,000 0,01004884 0,01875679 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01004884 0,01874225 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01004884 0,01872773 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01004884 0,01871324 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01004884 0,01869877 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01004884 0,01868432 ! startle response GO:0001964 28 16 0,000 0,01004884 0,01866989 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01004884 0,01865548 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01004884 0,0186411 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01004884 0,01862674 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01004884 0,0186124 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01004884 0,01859808 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01004884 0,01858378 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01004884 0,01856951 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01004884 0,01855526 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01004884 0,01854103 ! response to osmotic stress GO:0006970 25 16 0,000 0,01004884 0,01852682 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01004884 0,01851264 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01004884 0,01849847 ! fructose metabolic process GO:0006000 25 16 0,000 0,01004884 0,01848433 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01004884 0,01847021 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01004884 0,01845611 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01004884 0,01844203 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01004884 0,01842798 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01004884 0,01841394 ! axon cargo transport GO:0008088 43 16 0,000 0,01004884 0,01839993 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01004884 0,01838593 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01004884 0,01837196 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01004884 0,01835801 ! DNA replication initiation GO:0006270 27 16 0,000 0,01004884 0,01834409 ! neuron recognition GO:0008038 35 16 0,000 0,01004884 0,01833018 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01004884 0,01831629 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01004884 0,01830243 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01004884 0,01828858 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01004884 0,01827476 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01004884 0,01826095 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01004884 0,01824717 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01004884 0,01823341 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01004884 0,01821967 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01004884 0,01820595 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01004884 0,01819225 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01004884 0,01817857 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01004884 0,01816492 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01004884 0,01815128 ! defense response to virus GO:0051607 37 16 0,000 0,01004884 0,01813766 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0106737 0,01925107 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0106737 0,01923665 ! metencephalon development GO:0022037 30 17 0,000 0,0106737 0,01922225 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0106737 0,01920788 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0106737 0,01919352 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0106737 0,01917919 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0106737 0,01916487 ! signal complex assembly GO:0007172 41 17 0,000 0,0106737 0,01915058 ! endothelial cell migration GO:0043542 28 17 0,000 0,0106737 0,01913631 ! inositol metabolic process GO:0006020 28 17 0,000 0,0106737 0,01912206 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0106737 0,01910783 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0106737 0,01909363 ! glial cell development GO:0021782 27 17 0,000 0,0106737 0,01907944 ! limbic system development GO:0021761 36 17 0,000 0,0106737 0,01906528 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0106737 0,01905114 ! adult walking behavior GO:0007628 33 17 0,000 0,0106737 0,01903701 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0106737 0,01902291 ! heart looping GO:0001947 30 17 0,000 0,0106737 0,01900883 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0106737 0,01899477 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0106737 0,01898073 ! myoblast differentiation GO:0045445 45 17 0,000 0,0106737 0,01896671 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0106737 0,01895272 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0106737 0,01893874 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0106737 0,01892478 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0106737 0,01891085 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0106737 0,01889693 ! glycine metabolic process GO:0006544 28 17 0,000 0,0106737 0,01888304 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0106737 0,01886916 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0106737 0,01885531 ! NAD metabolic process GO:0019674 29 17 0,000 0,0106737 0,01884147 ! membrane budding GO:0006900 37 17 0,000 0,0106737 0,01882766 ! DNA integration GO:0015074 29 17 0,000 0,0106737 0,01881387 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0106737 0,0188001 ! regulation of protein binding GO:0043393 33 17 0,000 0,0106737 0,01878634 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0106737 0,01877261 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0106737 0,0187589 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0106737 0,0187452 ! genitalia development GO:0048806 30 17 0,000 0,0106737 0,01873153 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0106737 0,01871788 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0106737 0,01870425 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0106737 0,01869063 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0106737 0,01867704 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0106737 0,01866347 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0106737 0,01864991 ! steroid catabolic process GO:0006706 31 17 0,000 0,0106737 0,01863638 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0106737 0,01862286 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0106737 0,01860937 ! gas transport GO:0015669 25 17 0,000 0,0106737 0,01859589 ! organic cation transport GO:0015695 31 17 0,000 0,0106737 0,01858244 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0106737 0,018569 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0106737 0,01855559 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0106737 0,01854219 ! microspike assembly GO:0030035 36 17 0,000 0,0106737 0,01852881 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0106737 0,01851545 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0106737 0,01850211 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0112982 0,01957052 ! neuron maturation GO:0042551 42 18 0,000 0,0112982 0,01955644 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0112982 0,01954238 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0112982 0,01952835 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,0112982 0,01951433 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0112982 0,01950033 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0112982 0,01948635 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0112982 0,01947239 ! memory GO:0007613 31 18 0,000 0,0112982 0,01945845 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0112982 0,01944453 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0112982 0,01943063 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0112982 0,01941676 ! centrosome cycle GO:0007098 25 18 0,000 0,0112982 0,0194029 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0112982 0,01938906 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0112982 0,01937524 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0112982 0,01936144 ! response to retinoic acid GO:0032526 26 18 0,000 0,0112982 0,01934766 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0112982 0,0193339 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,0112982 0,01932015 ! response to fungus GO:0009620 21 18 0,000 0,0112982 0,01930643 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0112982 0,01929273 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0112982 0,01927905 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0112982 0,01926538 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0112982 0,01925174 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0112982 0,01923812 ! vitamin transport GO:0051180 27 18 0,000 0,0112982 0,01922451 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0112982 0,01921092 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0112982 0,01919736 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0112982 0,01918381 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0112982 0,01917028 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0112982 0,01915677 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0112982 0,01914328 ! nerve development GO:0021675 28 18 0,000 0,0112982 0,01912981 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0112982 0,01911636 ! protein secretion GO:0009306 39 19 0,000 0,01192231 0,02015818 ! positive regulation of translation GO:0045727 30 19 0,000 0,01192231 0,02014402 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01192231 0,02012988 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01192231 0,02011577 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01192231 0,02010167 ! skin development GO:0043588 36 19 0,000 0,01192231 0,02008759 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01192231 0,02007354 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01192231 0,0200595 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01192231 0,02004548 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01192231 0,02003148 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01192231 0,02001751 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01192231 0,02000355 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01192231 0,01998961 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01192231 0,01997569 ! cerebral cortex development GO:0021987 36 19 0,000 0,01192231 0,01996179 ! pigmentation during development GO:0048066 41 19 0,000 0,01192231 0,0199479 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,01192231 0,01993404 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,01192231 0,0199202 ! heme metabolic process GO:0042168 36 19 0,000 0,01192231 0,01990637 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01192231 0,01989257 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01192231 0,01987878 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01192231 0,01986502 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01192231 0,01985127 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01192231 0,01983754 ! peptide cross-linking GO:0018149 37 19 0,000 0,01192231 0,01982383 ! protein export from nucleus GO:0006611 36 19 0,000 0,01192231 0,01981014 ! heart process GO:0003015 30 19 0,000 0,01192231 0,01979647 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01192231 0,01978282 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01192231 0,01976918 ! visual learning GO:0008542 36 19 0,000 0,01192231 0,01975557 ! cellular pigmentation GO:0033059 36 19 0,000 0,01192231 0,01974197 ! G1 phase GO:0051318 40 19 0,000 0,01192231 0,01972839 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01192231 0,01971484 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01192231 0,0197013 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01192231 0,01968777 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01192231 0,01967427 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01192231 0,01966079 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01192231 0,01964732 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01192231 0,01963387 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01192231 0,01962044 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01192231 0,01960703 ! cilium assembly GO:0042384 37 19 0,000 0,01192231 0,01959364 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01192231 0,01958026 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01254606 0,0205906 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01254606 0,02057656 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01254606 0,02056254 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01254606 0,02054855 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01254606 0,02053457 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01254606 0,02052061 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01254606 0,02050667 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01254606 0,02049275 ! response to vitamin GO:0033273 31 20 0,000 0,01254606 0,02047884 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01254606 0,02046496 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01254606 0,02045109 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01254606 0,02043725 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01254606 0,02042342 ! response to alkaloid GO:0043279 38 20 0,000 0,01254606 0,02040961 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01254606 0,02039582 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01254606 0,02038205 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01254606 0,0203683 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01254606 0,02035456 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01254606 0,02034085 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01254606 0,02032715 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01254606 0,02031347 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01254606 0,02029981 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01254606 0,02028617 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01254606 0,02027254 ! body fluid secretion GO:0007589 31 20 0,000 0,01254606 0,02025894 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01254606 0,02024535 ! peptide secretion GO:0002790 35 20 0,000 0,01254606 0,02023178 ! stem cell differentiation GO:0048863 53 20 0,000 0,01254606 0,02021823 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01254606 0,0202047 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01254606 0,02019118 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01254606 0,02017768 ! sensory perception of pain GO:0019233 30 20 0,000 0,01254606 0,02016421 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01254606 0,02015074 ! diencephalon development GO:0021536 34 20 0,000 0,01254606 0,0201373 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01254606 0,02012388 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01254606 0,02011047 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01254606 0,02009708 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01254606 0,02008371 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01254606 0,02007036 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01254606 0,02005702 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01254606 0,0200437 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01254606 0,0200304 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01254606 0,02001712 ! regulation of glucose import GO:0046324 29 20 0,000 0,01254606 0,02000385 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01254606 0,01999061 ! actin filament-based movement GO:0030048 43 20 0,000 0,01254606 0,01997738 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01254606 0,01996416 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01254606 0,01995097 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01254606 0,01993779 ! negative regulation of translation GO:0017148 29 20 0,000 0,01254606 0,01992463 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01254606 0,01991149 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01254606 0,01989836 ! regulation of cell killing GO:0031341 42 21 0,000 0,01316943 0,02087329 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01316943 0,02085955 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01316943 0,02084582 ! hormone secretion GO:0046879 38 21 0,000 0,01316943 0,02083212 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01316943 0,02081843 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01316943 0,02080476 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01316943 0,02079111 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01316943 0,02077747 ! axis specification GO:0009798 38 21 0,000 0,01316943 0,02076386 ! ovarian follicle development GO:0001541 35 21 0,000 0,01316943 0,02075026 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01316943 0,02073668 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01316943 0,02072312 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01316943 0,02070957 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01316943 0,02069605 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01316943 0,02068254 ! cell aging GO:0007569 44 21 0,000 0,01316943 0,02066905 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01316943 0,02065557 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01316943 0,02064212 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01316943 0,02062868 ! cytolysis GO:0019835 24 21 0,000 0,01316943 0,02061526 ! vasodilation GO:0042311 39 21 0,000 0,01316943 0,02060185 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01316943 0,02058847 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01316943 0,0205751 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01316943 0,02056174 ! oogenesis GO:0048477 36 21 0,000 0,01316943 0,02054841 ! DNA modification GO:0006304 34 21 0,000 0,01316943 0,02053509 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01316943 0,02052179 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01316943 0,02050851 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01316943 0,02049525 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01316943 0,020482 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01316943 0,02046877 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01316943 0,02045555 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01316943 0,02044235 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01316943 0,02042917 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01316943 0,02041601 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01316943 0,02040286 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01316943 0,02038974 ! collagen catabolic process GO:0030574 28 21 0,000 0,01316943 0,02037662 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01316943 0,02036353 ! gut development GO:0048565 39 21 0,000 0,01316943 0,02035045 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01379243 0,02129948 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01379243 0,02128581 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01379243 0,02127217 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01379243 0,02125854 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01379243 0,02124493 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01379243 0,02123134 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01379243 0,02121777 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01379243 0,02120421 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01379243 0,02119067 ! regeneration GO:0031099 41 22 0,000 0,01379243 0,02117714 ! keratinization GO:0031424 28 22 0,000 0,01379243 0,02116364 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01379243 0,02115015 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01379243 0,02113668 ! sensory perception of taste GO:0050909 28 22 0,000 0,01379243 0,02112322 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01379243 0,02110979 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01379243 0,02109637 ! vacuolar transport GO:0007034 36 22 0,000 0,01379243 0,02108296 ! lysosome organization GO:0007040 41 22 0,000 0,01379243 0,02106958 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01379243 0,02105621 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01379243 0,02104286 ! fucose metabolic process GO:0006004 39 22 0,000 0,01379243 0,02102952 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01379243 0,0210162 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01379243 0,0210029 ! ureteric bud development GO:0001657 43 22 0,000 0,01379243 0,02098962 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01379243 0,02097635 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01379243 0,0209631 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01379243 0,02094986 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01379243 0,02093665 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01379243 0,02092345 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01379243 0,02091026 ! sarcomere organization GO:0045214 30 22 0,000 0,01379243 0,02089709 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01379243 0,02088394 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01379243 0,02087081 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01379243 0,02085769 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01379243 0,02084459 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01379243 0,0208315 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01379243 0,02081843 ! protein stabilization GO:0050821 39 22 0,000 0,01379243 0,02080538 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01441506 0,02173097 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01441506 0,02171736 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01441506 0,02170377 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01441506 0,0216902 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01441506 0,02167664 ! gluconeogenesis GO:0006094 33 23 0,000 0,01441506 0,0216631 ! viral genome replication GO:0019079 41 23 0,000 0,01441506 0,02164958 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01441506 0,02163607 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01441506 0,02162258 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01441506 0,02160911 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01441506 0,02159566 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01441506 0,02158222 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01441506 0,0215688 ! visual behavior GO:0007632 42 23 0,000 0,01441506 0,02155539 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01441506 0,021542 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01441506 0,02152863 ! response to ethanol GO:0045471 46 23 0,000 0,01441506 0,02151528 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01441506 0,02150194 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01441506 0,02148861 ! peroxisome organization GO:0007031 37 23 0,000 0,01441506 0,02147531 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01441506 0,02146202 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01441506 0,02144875 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01441506 0,02143549 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01441506 0,02142225 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01441506 0,02140903 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01441506 0,02139582 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01441506 0,02138263 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01441506 0,02136945 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01441506 0,0213563 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01441506 0,02134315 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01441506 0,02133003 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01441506 0,02131692 ! fatty acid transport GO:0015908 44 23 0,000 0,01441506 0,02130382 ! platelet activation GO:0030168 37 23 0,000 0,01441506 0,02129075 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01441506 0,02127768 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01441506 0,02126464 ! hormone transport GO:0009914 40 23 0,000 0,01441506 0,02125161 ! cell-cell recognition GO:0009988 25 23 0,000 0,01441506 0,02123859 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01441506 0,0212256 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01441506 0,02121261 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01441506 0,02119965 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01441506 0,0211867 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01441506 0,02117376 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01503731 0,02207429 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01503731 0,02206083 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01503731 0,02204739 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01503731 0,02203396 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01503731 0,02202055 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01503731 0,02200716 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01503731 0,02199378 ! vesicle docking GO:0048278 47 24 0,000 0,01503731 0,02198042 ! spinal cord development GO:0021510 47 24 0,000 0,01503731 0,02196707 ! vacuole organization GO:0007033 43 24 0,000 0,01503731 0,02195374 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01503731 0,02194043 ! digestive system process GO:0022600 39 24 0,000 0,01503731 0,02192713 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01503731 0,02191385 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01503731 0,02190059 ! regulation of behavior GO:0050795 43 24 0,000 0,01503731 0,02188734 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01503731 0,0218741 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01503731 0,02186089 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01503731 0,02184769 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01503731 0,0218345 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01503731 0,02182133 ! membrane depolarization GO:0051899 39 24 0,000 0,01503731 0,02180818 ! pallium development GO:0021543 49 24 0,000 0,01503731 0,02179504 ! pentose metabolic process GO:0019321 35 24 0,000 0,01503731 0,02178192 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01503731 0,02176881 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01503731 0,02175572 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01503731 0,02174265 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01503731 0,02172959 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01503731 0,02171655 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01503731 0,02170352 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01503731 0,02169051 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01503731 0,02167751 ! regulation of amine transport GO:0051952 40 24 0,000 0,01503731 0,02166453 ! protein tetramerization GO:0051262 52 24 0,000 0,01503731 0,02165157 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01565919 0,0225335 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01565919 0,02252003 ! myelination GO:0042552 45 25 0,000 0,01565919 0,02250658 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01565919 0,02249314 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01565919 0,02247972 ! phototransduction GO:0007602 33 25 0,000 0,01565919 0,02246632 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01565919 0,02245293 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01565919 0,02243956 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01565919 0,0224262 ! sperm motility GO:0030317 31 25 0,000 0,01565919 0,02241286 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01565919 0,02239953 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01565919 0,02238622 ! receptor metabolic process GO:0043112 46 25 0,000 0,01565919 0,02237293 ! chromosome condensation GO:0030261 45 25 0,000 0,01565919 0,02235965 ! response to starvation GO:0042594 42 25 0,000 0,01565919 0,02234639 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01565919 0,02233314 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,01565919 0,02231991 ! neural crest cell development GO:0014032 54 25 0,000 0,01565919 0,0223067 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01565919 0,0222935 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01565919 0,02228032 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01565919 0,02226715 ! interaction with host GO:0051701 62 25 0,000 0,01565919 0,022254 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01565919 0,02224086 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01565919 0,02222774 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01565919 0,02221463 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01565919 0,02220154 ! immunoglobulin production GO:0002377 55 25 0,000 0,01565919 0,02218847 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01565919 0,02217541 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01565919 0,02216236 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01565919 0,02214933 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01565919 0,02213632 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01565919 0,02212332 ! telomere organization GO:0032200 43 25 0,000 0,01565919 0,02211034 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01565919 0,02209737 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01565919 0,02208442 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0162807 0,02294749 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0162807 0,02293406 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0162807 0,02292064 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0162807 0,02290723 ! initiation of viral infection GO:0019059 57 26 0,000 0,0162807 0,02289384 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0162807 0,02288047 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0162807 0,02286711 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0162807 0,02285377 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0162807 0,02284045 ! molting cycle process GO:0022404 50 26 0,000 0,0162807 0,02282714 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0162807 0,02281384 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0162807 0,02280056 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,0162807 0,0227873 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0162807 0,02277405 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0162807 0,02276082 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,0162807 0,0227476 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0162807 0,0227344 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0162807 0,02272121 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,0162807 0,02270804 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0162807 0,02269488 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0162807 0,02268174 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0162807 0,02266862 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0162807 0,0226555 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0162807 0,02264241 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0162807 0,02262933 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0162807 0,02261626 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0162807 0,02260321 ! blastocyst development GO:0001824 49 26 0,000 0,0162807 0,02259018 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0162807 0,02257716 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0162807 0,02256415 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0162807 0,02255116 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01690184 0,02339806 ! neuron fate commitment GO:0048663 48 27 0,000 0,01690184 0,0233846 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01690184 0,02337116 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01690184 0,02335774 ! iron ion transport GO:0006826 59 27 0,000 0,01690184 0,02334433 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01690184 0,02333094 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01690184 0,02331756 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01690184 0,0233042 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01690184 0,02329085 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01690184 0,02327752 ! fat cell differentiation GO:0045444 50 27 0,000 0,01690184 0,0232642 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01690184 0,0232509 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01690184 0,02323761 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01690184 0,02322434 ! autophagy GO:0006914 41 27 0,000 0,01690184 0,02321109 ! male gonad development GO:0008584 44 27 0,000 0,01690184 0,02319785 ! response to toxin GO:0009636 47 27 0,000 0,01690184 0,02318462 ! primary neural tube formation GO:0014020 51 27 0,000 0,01690184 0,02317141 ! base-excision repair GO:0006284 41 27 0,000 0,01690184 0,02315822 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01690184 0,02314503 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01690184 0,02313187 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01690184 0,02311872 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01690184 0,02310558 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01690184 0,02309246 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01690184 0,02307936 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01690184 0,02306627 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01752261 0,02389988 ! circadian rhythm GO:0007623 50 28 0,000 0,01752261 0,02388634 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01752261 0,02387281 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01752261 0,0238593 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,01752261 0,02384581 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01752261 0,02383233 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,01752261 0,02381886 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01752261 0,02380542 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01752261 0,02379198 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01752261 0,02377856 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01752261 0,02376516 ! synaptogenesis GO:0007416 42 28 0,000 0,01752261 0,02375177 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01752261 0,0237384 ! lipid oxidation GO:0034440 43 28 0,000 0,01752261 0,02372504 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01752261 0,02371169 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01752261 0,02369836 ! translational initiation GO:0006413 65 29 0,000 0,018143 0,02452363 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,018143 0,02450986 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,018143 0,02449611 ! regulation of pH GO:0006885 43 29 0,000 0,018143 0,02448237 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,018143 0,02446864 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,018143 0,02445494 ! catechol metabolic process GO:0009712 54 29 0,000 0,018143 0,02444124 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,018143 0,02442757 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,018143 0,0244139 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,018143 0,02440026 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,018143 0,02438663 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,018143 0,02437301 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,018143 0,02435941 ! cell fate determination GO:0001709 60 29 0,000 0,018143 0,02434582 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,018143 0,02433225 ! detection of light stimulus GO:0009583 38 29 0,000 0,018143 0,0243187 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,018143 0,02430516 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,018143 0,02429163 ! tissue homeostasis GO:0001894 48 29 0,000 0,018143 0,02427812 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,018143 0,02426463 ! phenol metabolic process GO:0018958 55 30 0,000 0,01876303 0,02507991 ! zinc ion transport GO:0006829 45 30 0,000 0,01876303 0,02506599 ! membrane docking GO:0022406 61 30 0,000 0,01876303 0,02505207 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01876303 0,02503818 ! cell junction assembly GO:0034329 78 30 0,000 0,01876303 0,0250243 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01876303 0,02501044 ! acute-phase response GO:0006953 49 30 0,000 0,01876303 0,02499659 ! myofibril assembly GO:0030239 47 30 0,000 0,01876303 0,02498276 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01876303 0,02496894 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01876303 0,02495513 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01876303 0,02494135 ! phospholipid transport GO:0015914 51 30 0,000 0,01876303 0,02492758 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01876303 0,02491382 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01876303 0,02490008 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01876303 0,02488635 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01876303 0,02487264 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01876303 0,02485894 ! eye morphogenesis GO:0048592 60 30 0,000 0,01876303 0,02484526 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01876303 0,02483159 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01938268 0,02563756 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01938268 0,02562347 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01938268 0,0256094 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01938268 0,02559535 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01938268 0,02558131 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01938268 0,02556728 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01938268 0,02555327 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01938268 0,02553928 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01938268 0,0255253 ! ovulation cycle process GO:0022602 49 31 0,000 0,01938268 0,02551134 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01938268 0,02549739 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01938268 0,02548346 ! peptide transport GO:0015833 55 31 0,000 0,01938268 0,02546954 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01938268 0,02545564 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01938268 0,02544175 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01938268 0,02542788 ! natural killer cell activation GO:0030101 45 31 0,000 0,01938268 0,02541402 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01938268 0,02540018 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01938268 0,02538635 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01938268 0,02537254 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01938268 0,02535874 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01938268 0,02534496 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02000196 0,02614053 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02000196 0,02612634 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02000196 0,02611216 ! cholesterol transport GO:0030301 56 32 0,000 0,02000196 0,026098 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02000196 0,02608386 ! spliceosome assembly GO:0000245 67 32 0,000 0,02000196 0,02606973 ! spindle organization GO:0007051 46 32 0,000 0,02000196 0,02605561 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02000196 0,02604151 ! metanephros development GO:0001656 74 32 0,000 0,02000196 0,02602743 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02000196 0,02601336 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02000196 0,02599931 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02000196 0,02598527 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02000196 0,02597125 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02000196 0,02595724 ! muscle cell development GO:0055001 49 32 0,000 0,02000196 0,02594324 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02000196 0,02592927 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02000196 0,0259153 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02000196 0,02590136 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02000196 0,02588742 ! ovulation cycle GO:0042698 51 32 0,000 0,02000196 0,0258735 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02000196 0,0258596 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02000196 0,02584571 ! hindbrain development GO:0030902 61 32 0,000 0,02000196 0,02583184 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02000196 0,02581798 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02000196 0,02580414 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02000196 0,02579031 ! gene silencing GO:0016458 65 32 0,000 0,02000196 0,0257765 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02062087 0,02655986 ! post-embryonic development GO:0009791 69 33 0,000 0,02062087 0,02654565 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02062087 0,02653145 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02062087 0,02651727 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02062087 0,02650311 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02062087 0,02648896 ! cell fate specification GO:0001708 52 33 0,000 0,02062087 0,02647482 ! sterol transport GO:0015918 57 33 0,000 0,02062087 0,0264607 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02062087 0,0264466 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02062087 0,02643251 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02062087 0,02641843 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02062087 0,02640437 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02062087 0,02639033 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02123941 0,02716748 ! glial cell differentiation GO:0010001 63 34 0,000 0,02123941 0,02715304 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02123941 0,02713862 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02123941 0,02712422 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02123941 0,02710983 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02123941 0,02709546 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02123941 0,0270811 ! mismatch repair GO:0006298 46 34 0,000 0,02123941 0,02706675 ! spermatid development GO:0007286 63 34 0,000 0,02123941 0,02705242 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02123941 0,02703811 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02123941 0,02702381 ! placenta development GO:0001890 53 34 0,000 0,02123941 0,02700953 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02123941 0,02699526 ! regulation of muscle development GO:0048634 70 35 0,000 0,02185759 0,02776629 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,02185759 0,02775164 ! negative regulation of secretion GO:0051048 63 35 0,000 0,02185759 0,027737 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,02185759 0,02772238 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,02185759 0,02770777 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,02185759 0,02769318 ! odontogenesis GO:0042476 66 35 0,000 0,02185759 0,02767861 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,02185759 0,02766405 ! female gonad development GO:0008585 58 35 0,000 0,02185759 0,0276495 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,02185759 0,02763497 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,02185759 0,02762046 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,02185759 0,02760596 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,02185759 0,02759147 ! cytokine production GO:0001816 59 35 0,000 0,02185759 0,02757701 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,02185759 0,02756255 ! neural tube formation GO:0001841 67 35 0,000 0,02185759 0,02754811 ! vesicle localization GO:0051648 64 35 0,000 0,02185759 0,02753369 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02247539 0,02829711 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02247539 0,02828231 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02247539 0,02826753 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02247539 0,02825276 ! cell junction organization GO:0034330 86 36 0,000 0,02247539 0,02823801 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02247539 0,02822327 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02247539 0,02820855 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02247539 0,02819384 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02247539 0,02817915 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02247539 0,02816447 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02247539 0,02814981 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02247539 0,02813516 ! aerobic respiration GO:0009060 55 36 0,000 0,02247539 0,02812053 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02247539 0,02810592 ! embryonic organ development GO:0048568 57 36 0,000 0,02247539 0,02809132 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02247539 0,02807673 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,02247539 0,02806216 ! RNA export from nucleus GO:0006405 56 37 0,000 0,02309282 0,02881811 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02309282 0,02880317 ! meiosis I GO:0007127 65 37 0,000 0,02309282 0,02878825 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02309282 0,02877334 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02309282 0,02875845 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02309282 0,02874357 ! organic anion transport GO:0015711 68 37 0,000 0,02309282 0,02872871 ! tissue remodeling GO:0048771 76 37 0,000 0,02309282 0,02871386 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02309282 0,02869903 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02309282 0,02868421 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02309282 0,02866941 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02309282 0,02865463 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02309282 0,02863986 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02309282 0,0286251 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02309282 0,02861036 ! pigment metabolic process GO:0042440 80 37 0,000 0,02309282 0,02859564 ! spermatid differentiation GO:0048515 66 37 0,000 0,02309282 0,02858093 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02309282 0,02856623 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02370988 0,02931448 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02370988 0,02929942 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02370988 0,02928438 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02370988 0,02926936 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02370988 0,02925435 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02370988 0,02923935 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02370988 0,02922437 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02370988 0,02920941 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,02370988 0,02919446 ! lipid homeostasis GO:0055088 67 38 0,000 0,02370988 0,02917953 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02370988 0,02916461 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02370988 0,02914971 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02370988 0,02913482 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02370988 0,02911995 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02370988 0,02910509 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02370988 0,02909025 ! glucan metabolic process GO:0044042 62 38 0,000 0,02370988 0,02907542 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02432657 0,02981647 ! mammary gland development GO:0030879 86 39 0,000 0,02432657 0,02980129 ! learning GO:0007612 77 39 0,000 0,02432657 0,02978613 ! ear morphogenesis GO:0042471 60 39 0,000 0,02432657 0,02977098 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02432657 0,02975584 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02432657 0,02974072 ! segmentation GO:0035282 67 39 0,000 0,02432657 0,02972562 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02432657 0,02971053 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02432657 0,02969545 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02432657 0,02968039 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02432657 0,02966535 ! RNA modification GO:0009451 57 39 0,000 0,02432657 0,02965032 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02432657 0,02963531 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0249429 0,03037076 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0249429 0,03035539 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0249429 0,03034005 ! feeding behavior GO:0007631 59 40 0,000 0,0249429 0,03032472 ! negative regulation of binding GO:0051100 72 40 0,000 0,0249429 0,0303094 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0249429 0,0302941 ! mesenchymal cell development GO:0014031 87 40 0,000 0,0249429 0,03027882 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0249429 0,03026355 ! maintenance of protein location GO:0045185 91 40 0,000 0,0249429 0,03024829 ! cytokinesis GO:0000910 72 40 0,000 0,0249429 0,03023305 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02555885 0,03096405 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02555885 0,03094847 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02555885 0,0309329 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02555885 0,03091735 ! gliogenesis GO:0042063 88 41 0,000 0,02555885 0,03090181 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02555885 0,03088629 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02555885 0,03087078 ! T cell differentiation GO:0030217 81 41 0,000 0,02555885 0,03085529 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,02555885 0,03083982 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02555885 0,03082436 ! female gamete generation GO:0007292 61 41 0,000 0,02555885 0,03080892 ! polyol metabolic process GO:0019751 66 41 0,000 0,02555885 0,03079349 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02555885 0,03077808 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02617444 0,0315036 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,02617444 0,03148785 ! regulation of tube size GO:0035150 71 42 0,000 0,02617444 0,03147212 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02617444 0,0314564 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02617444 0,03144069 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,02617444 0,031425 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,02617444 0,03140933 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02617444 0,03139367 ! neuron migration GO:0001764 79 42 0,000 0,02617444 0,03137803 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02617444 0,0313624 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02617444 0,03134679 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,02678966 0,03206762 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,02678966 0,03205167 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,02678966 0,03203574 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,02678966 0,03201983 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,02678966 0,03200393 ! glucose transport GO:0015758 65 43 0,000 0,02678966 0,03198805 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,02678966 0,03197218 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,02678966 0,03195633 ! neural tube development GO:0021915 77 43 0,000 0,02678966 0,03194049 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,02678966 0,03192467 ! striated muscle contraction GO:0006941 77 43 0,000 0,02678966 0,03190887 ! phagocytosis GO:0006909 90 43 0,000 0,02678966 0,03189308 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,02678966 0,03187731 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02740451 0,03259281 ! hexose transport GO:0008645 67 44 0,000 0,02740451 0,0325767 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02740451 0,03256062 ! male sex differentiation GO:0046661 76 44 0,000 0,02740451 0,03254454 ! double-strand break repair GO:0006302 81 44 0,000 0,02740451 0,03252849 ! biopolymer methylation GO:0043414 84 44 0,000 0,02740451 0,03251245 ! B cell differentiation GO:0030183 107 44 0,000 0,02740451 0,03249643 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02740451 0,03248042 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02740451 0,03246443 ! developmental growth GO:0048589 82 44 0,000 0,02740451 0,03244845 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02740451 0,03243249 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02801899 0,03314341 ! glycolysis GO:0006096 65 45 0,000 0,02801899 0,03312712 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02801899 0,03311085 ! leukocyte migration GO:0050900 68 45 0,000 0,02801899 0,0330946 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02801899 0,03307836 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,02801899 0,03306213 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,02801899 0,03304593 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02801899 0,03302974 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02801899 0,03301356 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02801899 0,0329974 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02801899 0,03298126 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02801899 0,03296513 ! cell growth GO:0016049 84 45 0,000 0,02801899 0,03294902 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,0286331 0,03365474 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0286331 0,03363831 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0286331 0,03362189 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0286331 0,03360549 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0286331 0,0335891 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0286331 0,03357273 ! pigmentation GO:0043473 100 46 0,000 0,0286331 0,03355638 ! response to insulin stimulus GO:0032868 95 46 0,000 0,0286331 0,03354004 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0286331 0,03352372 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02924685 0,03422564 ! response to calcium ion GO:0051592 81 47 0,000 0,02924685 0,03420901 ! endosome transport GO:0016197 108 47 0,000 0,02924685 0,03419238 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02924685 0,03417578 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02924685 0,03415919 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02924685 0,03414261 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02924685 0,03412605 ! JNK cascade GO:0007254 91 47 0,000 0,02924685 0,03410951 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02924685 0,03409299 ! methylation GO:0032259 90 47 0,000 0,02924685 0,03407648 ! protein homooligomerization GO:0051260 76 47 0,000 0,02924685 0,03405998 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,02986023 0,03475748 ! mitochondrial transport GO:0006839 82 48 0,000 0,02986023 0,03474067 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02986023 0,03472388 ! cellular component disassembly GO:0022411 86 48 0,000 0,02986023 0,03470711 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02986023 0,03469035 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02986023 0,03467361 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02986023 0,03465688 ! activation of caspase activity GO:0006919 84 48 0,000 0,02986023 0,03464017 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02986023 0,03462348 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02986023 0,0346068 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02986023 0,03459014 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02986023 0,03457349 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03047324 0,03526629 ! regulation of action potential GO:0001508 95 49 0,000 0,03047324 0,03524934 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03047324 0,0352324 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03047324 0,03521548 ! regulation of ion transport GO:0043269 77 49 0,000 0,03047324 0,03519857 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03047324 0,03518168 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03047324 0,03516481 ! endocrine system development GO:0035270 104 49 0,000 0,03047324 0,03514795 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03047324 0,03513111 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03047324 0,03511428 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03047324 0,03509747 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03047324 0,03508068 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03108589 0,03576884 ! neuromuscular process GO:0050905 99 50 0,000 0,03108589 0,03575174 ! regulation of ossification GO:0030278 117 50 0,000 0,03108589 0,03573466 ! inner ear development GO:0048839 79 50 0,000 0,03108589 0,03571759 ! histone modification GO:0016570 91 50 0,000 0,03108589 0,03570055 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03108589 0,03568351 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03108589 0,0356665 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03108589 0,0356495 ! positive regulation of binding GO:0051099 78 51 0,000 0,03169817 0,03633434 ! viral infectious cycle GO:0019058 99 51 0,000 0,03169817 0,03631704 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03169817 0,03629975 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03169817 0,03628249 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03169817 0,03626523 ! excretion GO:0007588 83 51 0,000 0,03169817 0,036248 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03169817 0,03623078 ! chromatin remodeling GO:0006338 109 51 0,000 0,03169817 0,03621357 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03169817 0,03619639 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03169817 0,03617921 ! vesicle organization GO:0016050 107 51 0,000 0,03169817 0,03616206 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,03169817 0,03614492 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,03169817 0,0361278 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03169817 0,03611069 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,03231008 0,03679037 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,03231008 0,03677296 ! membrane fusion GO:0006944 110 52 0,000 0,03231008 0,03675558 ! positive regulation of growth GO:0045927 90 52 0,000 0,03231008 0,03673821 ! covalent chromatin modification GO:0016569 101 52 0,000 0,03231008 0,03672085 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,03231008 0,03670351 ! amino acid activation GO:0043038 92 52 0,000 0,03231008 0,03668619 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,03231008 0,03666889 ! synapse organization GO:0050808 85 52 0,000 0,03231008 0,0366516 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,03292162 0,03732772 ! RNA catabolic process GO:0006401 93 53 0,000 0,03292162 0,03731014 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,03292162 0,03729257 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,03292162 0,03727502 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,03292162 0,03725749 ! cell maturation GO:0048469 100 53 0,000 0,03292162 0,03723997 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,03292162 0,03722247 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,03292162 0,03720499 ! response to UV GO:0009411 104 53 0,000 0,03292162 0,03718752 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0335328 0,03786012 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0335328 0,03784236 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0335328 0,03782462 ! cell recognition GO:0008037 85 54 0,000 0,0335328 0,0378069 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0335328 0,03778919 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0335328 0,0377715 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0335328 0,03775382 ! chloride transport GO:0006821 90 55 0,000 0,03414361 0,03842354 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,03414361 0,03840558 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,03414361 0,03838763 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,03414361 0,0383697 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,03414361 0,03835179 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,03414361 0,03833389 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,03414361 0,03831601 ! aging GO:0007568 103 55 0,000 0,03414361 0,03829815 ! heart morphogenesis GO:0003007 97 55 0,000 0,03414361 0,03828031 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,03414361 0,03826248 ! RNA elongation GO:0006354 79 55 0,000 0,03414361 0,03824466 ! nuclear export GO:0051168 97 55 0,000 0,03414361 0,03822687 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,03414361 0,03820909 ! regulation of actin filament length GO:0030832 105 56 0,000 0,03475406 0,03887414 ! sensory perception of smell GO:0007608 80 56 0,000 0,03475406 0,03885607 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,03475406 0,03883803 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,03475406 0,03882 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,03475406 0,03880198 ! regulation of DNA replication GO:0006275 101 56 0,000 0,03475406 0,03878399 ! proton transport GO:0015992 94 56 0,000 0,03475406 0,038766 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,03475406 0,03874804 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,03536414 0,03940997 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,03536414 0,03939173 ! muscle fiber development GO:0048747 112 57 0,000 0,03536414 0,0393735 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,03536414 0,03935529 ! lipid modification GO:0030258 97 57 0,000 0,03536414 0,03933709 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,03536414 0,03931891 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,03536414 0,03930075 ! maintenance of location GO:0051235 118 57 0,000 0,03536414 0,03928261 ! hydrogen transport GO:0006818 97 58 0,000 0,03597386 0,03994144 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,03597386 0,03992302 ! regulation of endocytosis GO:0030100 91 58 0,000 0,03597386 0,03990461 ! adult behavior GO:0030534 99 58 0,000 0,03597386 0,03988622 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,03597386 0,03986785 ! positive regulation of secretion GO:0051047 95 59 0,000 0,03658321 0,0405245 ! regulation of cellular component size GO:0032535 109 59 0,000 0,03658321 0,04050585 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,03658321 0,04048722 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,03658321 0,0404686 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,03658321 0,04045 ! DNA catabolic process GO:0006308 86 59 0,000 0,03658321 0,04043142 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,03658321 0,04041286 ! establishment of organelle localization GO:0051656 109 59 0,000 0,03658321 0,04039431 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0371922 0,0410479 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,0371922 0,04102908 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0371922 0,04101028 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0371922 0,04099149 ! camera-type eye development GO:0043010 116 60 0,000 0,0371922 0,04097272 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,0371922 0,04095397 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0371922 0,04093524 ! kidney development GO:0001822 122 60 0,000 0,0371922 0,04091652 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,03780082 0,04156708 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,03780082 0,04154809 ! tRNA processing GO:0008033 89 61 0,000 0,03780082 0,04152912 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,03780082 0,04151017 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,03780082 0,04149123 ! ear development GO:0043583 103 62 0,000 0,03840908 0,04213964 ! viral reproductive process GO:0022415 126 62 0,000 0,03840908 0,04212044 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,03840908 0,04210125 ! gonad development GO:0008406 98 62 0,000 0,03840908 0,04208208 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,03840908 0,04206292 ! regulation of mitosis GO:0007088 105 63 0,000 0,03901697 0,0427092 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,03901697 0,04268978 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,03901697 0,04267038 ! detection of external stimulus GO:0009581 91 63 0,000 0,03901697 0,04265099 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,03901697 0,04263162 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,03901697 0,04261227 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,0396245 0,04325615 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,0396245 0,04323653 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,0396245 0,04321693 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,0396245 0,04319735 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,04023166 0,0438394 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,04023166 0,04381955 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,04023166 0,04379972 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,04023166 0,04377991 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,04023166 0,04376012 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,04083847 0,04440007 ! actin filament organization GO:0007015 148 66 0,000 0,04083847 0,04438001 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,04083847 0,04435998 ! extracellular matrix organization GO:0030198 133 66 0,000 0,04083847 0,04433996 ! secondary metabolic process GO:0019748 116 66 0,000 0,04083847 0,04431996 ! developmental maturation GO:0021700 116 66 0,000 0,04083847 0,04429998 ! cell projection assembly GO:0030031 120 66 0,000 0,04083847 0,04428001 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,0414449 0,04491732 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,0414449 0,04489709 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,0414449 0,04487689 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,0414449 0,0448567 ! activation of MAPK activity GO:0000187 115 67 0,000 0,0414449 0,04483653 ! lung development GO:0030324 144 67 0,000 0,0414449 0,04481638 ! chromosome segregation GO:0007059 113 67 0,000 0,0414449 0,04479624 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,0414449 0,04477613 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,0414449 0,04475603 ! hexose catabolic process GO:0019320 104 67 0,000 0,0414449 0,04473595 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,0414449 0,04471589 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,0414449 0,04469585 ! adaptive immune response GO:0002250 119 67 0,000 0,0414449 0,04467582 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,0414449 0,04465582 ! amino acid transport GO:0006865 125 68 0,000 0,04205098 0,04528857 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,04205098 0,0452683 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,04205098 0,04524806 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,04205098 0,04522783 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,04205098 0,04520762 ! viral reproduction GO:0016032 134 68 0,000 0,04205098 0,04518743 ! regulation of lipase activity GO:0060191 130 68 0,000 0,04205098 0,04516726 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,04205098 0,0451471 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,04205098 0,04512697 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,04265669 0,04575658 ! negative regulation of cell size GO:0045792 134 69 0,000 0,04265669 0,04573618 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,04265669 0,04571581 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,04265669 0,04569546 ! urogenital system development GO:0001655 137 69 0,000 0,04265669 0,04567512 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,04265669 0,0456548 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,04265669 0,0456345 ! antigen processing and presentation GO:0019882 104 69 0,000 0,04265669 0,04561422 ! appendage morphogenesis GO:0035107 135 70 0,000 0,04326204 0,04624099 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,04326204 0,04622046 ! amine catabolic process GO:0009310 117 71 0,000 0,04386703 0,04684601 ! reproductive structure development GO:0048608 113 71 0,000 0,04386703 0,04682523 ! appendage development GO:0048736 136 71 0,000 0,04386703 0,04680446 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,04386703 0,04678372 ! B cell activation GO:0042113 160 71 0,000 0,04386703 0,04676299 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,04386703 0,04674228 ! regulation of immune effector process GO:0002697 137 71 0,000 0,04386703 0,04672159 ! acute inflammatory response GO:0002526 113 72 0,000 0,04447165 0,0473446 ! regulation of caspase activity GO:0043281 122 72 0,000 0,04447165 0,04732366 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,04447165 0,04730274 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,04447165 0,04728183 ! carbohydrate transport GO:0008643 110 72 0,000 0,04447165 0,04726095 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,04447165 0,04724008 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,04447165 0,04721924 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,04447165 0,04719841 ! respiratory system development GO:0060541 153 72 0,000 0,04447165 0,0471776 ! learning or memory GO:0007611 147 73 0,000 0,04507591 0,04779755 ! regulation of blood pressure GO:0008217 125 73 0,000 0,04507591 0,04777649 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,04507591 0,04775546 ! axon guidance GO:0007411 139 73 0,000 0,04507591 0,04773444 ! fertilization GO:0009566 90 73 0,000 0,04507591 0,04771344 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,04567981 0,04833141 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,04567981 0,04831016 ! neurotransmitter transport GO:0006836 123 74 0,000 0,04567981 0,04828894 ! meiosis GO:0007126 121 74 0,000 0,04567981 0,04826773 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,04567981 0,04824654 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,04567981 0,04822537 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,04567981 0,04820422 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,04567981 0,04818309 ! eye development GO:0001654 143 74 0,000 0,04567981 0,04816197 ! organelle localization GO:0051640 136 74 0,000 0,04567981 0,04814088 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,04628335 0,04875558 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,04628335 0,04873424 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,04628335 0,04871292 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,04628335 0,04869162 ! meiotic cell cycle GO:0051321 122 75 0,000 0,04628335 0,04867034 ! rhythmic process GO:0048511 128 75 0,000 0,04628335 0,04864908 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,04628335 0,04862783 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,04688652 0,04924006 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,04688652 0,04921858 ! defense response to bacterium GO:0042742 89 76 0,000 0,04688652 0,04919711 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,04688652 0,04917567 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,04688652 0,04915424 ! regulation of catabolic process GO:0009894 161 76 0,000 0,04688652 0,04913283 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,04748934 0,04974286 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,04748934 0,04972121 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,04748934 0,04969959 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,04748934 0,04967798 ! blood coagulation GO:0007596 146 78 0,000 0,04809179 0,05028633 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,04809179 0,05026449 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,04809179 0,05024266 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,04809179 0,05022086 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,04869389 0,05082754 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,04869389 0,0508055 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,04869389 0,05078348 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,04869389 0,05076148 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,04869389 0,05073949 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,04869389 0,05071753 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,04869389 0,05069558 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,04929562 0,05129985 ! response to metal ion GO:0010038 140 80 0,000 0,04929562 0,05127767 ! muscle cell differentiation GO:0042692 159 80 0,000 0,04929562 0,05125551 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,04929562 0,05123337 ! protein import into nucleus GO:0006606 158 80 0,000 0,04929562 0,05121125 ! inorganic anion transport GO:0015698 138 80 0,000 0,04929562 0,05118915 ! T cell activation GO:0042110 168 81 0,000 0,04989699 0,05179127 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,04989699 0,05176893 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,04989699 0,05174662 ! digestion GO:0007586 112 81 0,000 0,04989699 0,05172432 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,04989699 0,05170205 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,04989699 0,05167979 ! nuclear import GO:0051170 161 81 0,000 0,04989699 0,05165755 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,04989699 0,05163533 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,050498 0,05223482 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,050498 0,05221237 ! response to drug GO:0042493 143 82 0,000 0,050498 0,05218994 ! response to nutrient GO:0007584 125 82 0,000 0,050498 0,05216753 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,050498 0,05214514 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,050498 0,05212277 ! response to oxygen levels GO:0070482 176 83 0,000 0,05109865 0,05272013 ! regulation of lyase activity GO:0051339 160 83 0,000 0,05109865 0,05269754 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,05169894 0,05329377 ! hemostasis GO:0007599 158 84 0,000 0,05169894 0,05327094 ! negative regulation of transport GO:0051051 153 84 0,000 0,05169894 0,05324814 ! negative regulation of growth GO:0045926 155 84 0,000 0,05169894 0,05322535 ! regulation of ligase activity GO:0051340 142 84 0,000 0,05169894 0,05320259 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,05169894 0,05317984 ! nucleosome assembly GO:0006334 122 85 0,000 0,05229887 0,05377397 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,05229887 0,053751 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,05229887 0,05372805 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,05289844 0,05432081 ! response to inorganic substance GO:0010035 153 86 0,000 0,05289844 0,05429763 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,05289844 0,05427448 ! chromatin assembly GO:0031497 124 86 0,000 0,05289844 0,05425134 ! tube morphogenesis GO:0035239 176 86 0,000 0,05289844 0,05422823 ! mitochondrion organization GO:0007005 148 86 0,000 0,05289844 0,05420513 ! alcohol catabolic process GO:0046164 130 86 0,000 0,05289844 0,05418206 ! amine transport GO:0015837 155 86 0,000 0,05289844 0,054159 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,05349765 0,05474919 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,05349765 0,05472592 ! protein localization in nucleus GO:0034504 176 87 0,000 0,05349765 0,05470266 ! regulation of protein transport GO:0051223 154 87 0,000 0,05349765 0,05467942 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,05409651 0,05526802 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,05409651 0,05524456 ! regulation of DNA binding GO:0051101 155 88 0,000 0,05409651 0,05522113 ! gland development GO:0048732 206 88 0,000 0,05409651 0,05519771 ! regulation of neurological system process GO:0031644 148 88 0,000 0,05409651 0,05517431 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,05409651 0,05515093 ! cellular defense response GO:0006968 114 89 0,000 0,054695 0,05573747 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,054695 0,05571387 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,054695 0,0556903 ! ossification GO:0001503 188 90 0,000 0,05529313 0,0562755 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,05529313 0,05625171 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,05529313 0,05622793 ! sex differentiation GO:0007548 145 90 0,000 0,05529313 0,05620418 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,05529313 0,05618044 ! bone development GO:0060348 189 91 0,000 0,05589091 0,05676384 ! sterol metabolic process GO:0016125 152 91 0,000 0,05589091 0,05673989 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,05589091 0,05671596 ! regulation of defense response GO:0031347 149 92 0,000 0,05648833 0,05729803 ! nucleosome organization GO:0034728 138 92 0,000 0,05648833 0,05727388 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,05648833 0,05724976 ! vitamin metabolic process GO:0006766 139 92 0,000 0,05648833 0,05722565 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,05708539 0,05780616 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,05708539 0,05778185 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,05708539 0,05775755 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,05708539 0,05773327 ! regulation of membrane potential GO:0042391 164 93 0,000 0,05708539 0,05770901 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,05708539 0,05768477 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,05768209 0,05826327 ! female pregnancy GO:0007565 164 94 0,000 0,05768209 0,05823882 ! transcription initiation GO:0006352 153 94 0,000 0,05768209 0,05821439 ! regulation of T cell activation GO:0050863 158 94 0,000 0,05768209 0,05818998 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,05827844 0,05876694 ! forebrain development GO:0030900 188 95 0,000 0,05827844 0,05874232 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,05827844 0,05871772 ! leukocyte differentiation GO:0002521 202 96 0,000 0,05887442 0,05929337 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,05887442 0,05926856 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,05887442 0,05924377 ! positive regulation of immune response GO:0050778 156 96 0,000 0,05887442 0,059219 ! detection of stimulus GO:0051606 151 96 0,000 0,05887442 0,05919426 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,05947005 0,05976815 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,05947005 0,05974319 ! protein ubiquitination GO:0016567 217 97 0,000 0,05947005 0,05971826 ! hormone metabolic process GO:0042445 157 97 0,000 0,05947005 0,05969334 ! regulation of protein localization GO:0032880 176 97 0,000 0,05947005 0,05966845 ! response to virus GO:0009615 160 98 0,000 0,06006532 0,06024059 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,06006532 0,06021549 ! interphase GO:0051325 213 98 0,000 0,06006532 0,06019041 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,06006532 0,06016535 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,06066024 0,06073597 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,06066024 0,0607107 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,06066024 0,06068546 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,0612548 0,0612548