pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/4931-5-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 3,000 8,297E-11 2,963E-07 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 2,306E-08 4,118E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 3,000 5,693E-08 6,776E-05 ! protein kinase regulator activity GO:0019887 64 64 3,000 1,561E-07 1,394E-04 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 2,000 2,789E-07 1,992E-04 ! kinase regulator activity GO:0019207 77 77 3,000 3,306E-07 1,968E-04 ! interphase of mitotic cell cycle GO:0051329 84 82 3,000 4,264E-07 2,175E-04 GO:0051325|interphase, ! negative regulation of phosphorylation GO:0042326 26 22 2,000 6,301E-07 2,813E-04 ! negative regulation of phosphorus metabolic process GO:0010563 27 23 2,000 7,243E-07 2,874E-04 GO:0045936|negative regulation of phosphate metabolic process, ! glycolysis GO:0006096 42 42 2,000 4,655E-06 1,662E-03 ! cytoplasmic dynein complex GO:0005868 6 5 1,000 6,073E-06 1,971E-03 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 2,000 6,143E-06 1,828E-03 ! response to UV GO:0009411 50 49 2,000 7,446E-06 2,045E-03 ! glucose catabolic process GO:0006007 52 52 2,000 8,919E-06 2,275E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 9,105E-06 2,168E-03 ! malate metabolic process GO:0006108 6 6 1,000 9,105E-06 2,032E-03 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 1,000 1,274E-05 2,676E-03 ! phosphofructokinase activity GO:0008443 7 7 1,000 1,274E-05 2,528E-03 ! hexose catabolic process GO:0019320 63 62 2,000 1,519E-05 2,856E-03 ! malate dehydrogenase activity GO:0016615 8 8 1,000 1,698E-05 3,032E-03 ! T cell homeostasis GO:0043029 9 8 1,000 1,698E-05 2,887E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 1,698E-05 2,756E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 2,182E-05 3,388E-03 ! monosaccharide catabolic process GO:0046365 72 71 2,000 2,287E-05 3,402E-03 ! cellular carbohydrate catabolic process GO:0044275 75 74 2,000 2,59E-05 3,699E-03 ! alcohol catabolic process GO:0046164 83 80 2,000 3,274E-05 4,496E-03 ! thymus development GO:0048538 12 11 1,000 3,331E-05 4,405E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 3,331E-05 4,248E-03 ! lymphocyte homeostasis GO:0002260 14 12 1,000 3,995E-05 4,92E-03 ! carbohydrate catabolic process GO:0016052 95 94 2,000 5,307E-05 6,317E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 1,000 5,504E-05 6,34E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 5,504E-05 6,142E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,032E-04 0,01116587 GO:0030968|endoplasmic reticulum unfolded protein response, ! synaptic vesicle transport GO:0048489 21 20 1,000 1,146E-04 0,01203617 ! leukocyte homeostasis GO:0001776 22 20 1,000 1,146E-04 0,01169228 ! dicarboxylic acid metabolic process GO:0043648 22 21 1,000 1,266E-04 0,01255839 ! activation of pro-apoptotic gene products GO:0008633 22 21 1,000 1,266E-04 0,01221897 ! acetyl-CoA catabolic process GO:0046356 21 21 1,000 1,266E-04 0,01189742 GO:0006099|tricarboxylic acid cycle, ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 1,266E-04 0,01159236 ! coenzyme catabolic process GO:0009109 22 22 1,000 1,392E-04 0,01242718 ! positive regulation of B cell activation GO:0050871 26 22 1,000 1,392E-04 0,01212408 ! neural tube closure GO:0001843 24 22 1,000 1,392E-04 0,01183541 GO:0060606|tube closure, ! carbohydrate kinase activity GO:0019200 22 22 1,000 1,392E-04 0,01156017 ! tube lumen formation GO:0035148 26 23 1,000 1,524E-04 0,01236778 ! primary neural tube formation GO:0014020 26 24 1,000 1,662E-04 0,01318633 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 1,662E-04 0,01289968 ! acetyl-CoA metabolic process GO:0006084 25 25 1,000 1,805E-04 0,01371685 ! fat cell differentiation GO:0045444 26 26 1,000 1,955E-04 0,01454376 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 1,955E-04 0,01424694 ! cellular response to extracellular stimulus GO:0031668 27 26 1,000 1,955E-04 0,013962 ! neural tube formation GO:0001841 29 27 1,000 2,11E-04 0,01477661 ! dynein complex GO:0030286 29 28 1,000 2,272E-04 0,01560019 ! cofactor catabolic process GO:0051187 30 28 1,000 2,272E-04 0,01530584 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 2,272E-04 0,0150224 ! protein kinase inhibitor activity GO:0004860 28 28 1,000 2,272E-04 0,01474927 ! spindle organization GO:0007051 30 29 1,000 2,439E-04 0,01555188 ! kinase inhibitor activity GO:0019210 30 30 1,000 2,612E-04 0,01636299 ! embryonic epithelial tube formation GO:0001838 32 30 1,000 2,612E-04 0,01608087 ! meiosis I GO:0007127 31 31 1,000 2,791E-04 0,01689089 ! aerobic respiration GO:0009060 32 32 1,000 2,975E-04 0,01770866 ! regulation of B cell activation GO:0050864 36 32 1,000 2,975E-04 0,01741835 ! neural tube development GO:0021915 36 34 1,000 3,362E-04 0,0193657 ! response to calcium ion GO:0051592 39 35 1,000 3,564E-04 0,02020421 ! female gamete generation GO:0007292 38 35 1,000 3,564E-04 0,01988852 ! positive regulation of leukocyte proliferation GO:0070665 40 36 1,000 3,772E-04 0,02072508 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of cell cycle GO:0045787 39 39 1,000 4,431E-04 0,02397473 ! morphogenesis of embryonic epithelium GO:0016331 44 42 1,000 5,142E-04 0,02740426 ! induction of apoptosis by intracellular signals GO:0008629 46 43 1,000 5,39E-04 0,02830558 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 5,644E-04 0,02921049 ! epithelial tube morphogenesis GO:0060562 47 45 1,000 5,904E-04 0,03011878 ! microtubule binding GO:0008017 49 46 1,000 6,17E-04 0,03103028 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 6,17E-04 0,0305993 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 7,883E-04 0,03856073 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 9,466E-04 0,0456818 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 9,8E-04 0,04666133 GO:0045937|positive regulation of phosphate metabolic process, ! homeostasis of number of cells GO:0048872 62 58 1,000 9,8E-04 0,04604736 ! dendrite GO:0030425 61 59 1,000 1,014E-03 0,04702278 ! cell soma GO:0043025 63 59 1,000 1,014E-03 0,04641992 ! negative regulation of protein kinase activity GO:0006469 67 61 1,000 1,083E-03 0,04897562 ! negative regulation of kinase activity GO:0033673 68 62 1,000 1,119E-03 0,04995293 ! microtubule motor activity GO:0003777 67 63 1,000 1,155E-03 0,05093076 ! negative regulation of cell growth GO:0030308 68 65 1,000 1,229E-03 0,05353274 ! negative regulation of transferase activity GO:0051348 71 65 1,000 1,229E-03 0,05288776 ! response to metal ion GO:0010038 69 65 1,000 1,229E-03 0,05225815 ! positive regulation of protein modification process GO:0031401 69 65 1,000 1,229E-03 0,05164334 ! response to unfolded protein GO:0006986 68 66 1,000 1,267E-03 0,05261412 ! negative regulation of cell size GO:0045792 70 67 1,000 1,305E-03 0,0535854 ! tubulin binding GO:0015631 70 67 1,000 1,305E-03 0,05297647 ! positive regulation of lymphocyte activation GO:0051251 72 67 1,000 1,305E-03 0,05238123 ! response to inorganic substance GO:0010035 74 70 1,000 1,424E-03 0,05650178 ! meiosis GO:0007126 73 72 1,000 1,506E-03 0,05908999 GO:0051327|M phase of meiotic cell cycle, ! response to protein stimulus GO:0051789 74 72 1,000 1,506E-03 0,05844771 ! meiotic cell cycle GO:0051321 75 73 1,000 1,548E-03 0,05942106 ! positive regulation of cell activation GO:0050867 80 75 1,000 1,633E-03 0,0620212 GO:0002696|positive regulation of leukocyte activation, ! phosphoinositide-mediated signaling GO:0048015 79 75 1,000 1,633E-03 0,06136834 ! tube morphogenesis GO:0035239 79 75 1,000 1,633E-03 0,06072909 ! negative regulation of growth GO:0045926 84 80 1,000 1,855E-03 0,06828699 ! protein kinase binding GO:0019901 89 80 1,000 1,855E-03 0,06759018 ! cellular respiration GO:0045333 85 85 1,000 2,091E-03 0,07541769 ! microtubule cytoskeleton organization GO:0000226 92 87 1,000 2,189E-03 0,07816907 ! cell cycle arrest GO:0007050 92 87 1,000 2,189E-03 0,07739512 ! in utero embryonic development GO:0001701 97 95 1,000 2,603E-03 0,09113744 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 2,603E-03 0,09025261 ! microtubule associated complex GO:0005875 104 97 1,000 2,712E-03 0,09312413 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 1,000 2,767E-03 0,09411626 ! protein C-terminus binding GO:0008022 106 99 1,000 2,823E-03 0,09510757 ! kinase binding GO:0019900 108 99 1,000 2,823E-03 0,09421872 ! tRNA transcription GO:0009304 5 5 0,000 4,066E-03 0,13444607 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 4,066E-03 0,13321262 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 4,066E-03 0,1320016 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 4,066E-03 0,1308124 ! response to oxygen radical GO:0000305 5 5 0,000 4,066E-03 0,12964443 ! positive regulation of axon extension GO:0045773 6 5 0,000 4,066E-03 0,12849713 ! negative regulation of bone resorption GO:0045779 5 5 0,000 4,066E-03 0,12736997 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 4,066E-03 0,1262624 ! regulation of interferon-beta production GO:0032648 6 5 0,000 4,066E-03 0,12517393 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 4,066E-03 0,12410407 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 4,066E-03 0,12305234 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 4,066E-03 0,12201829 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 4,066E-03 0,12100147 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 4,066E-03 0,12000146 ! N-terminal protein lipidation GO:0006498 5 5 0,000 4,066E-03 0,11901784 ! glycolipid transport GO:0046836 5 5 0,000 4,066E-03 0,11805021 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 4,066E-03 0,11709819 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 4,066E-03 0,11616141 ! protein amino acid sulfation GO:0006477 5 5 0,000 4,066E-03 0,11523949 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 4,066E-03 0,11433209 ! embryonic camera-type eye development GO:0031076 7 5 0,000 4,066E-03 0,11343888 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 4,066E-03 0,1125595 ! selenocysteine incorporation GO:0001514 5 5 0,000 4,066E-03 0,11169366 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 4,066E-03 0,11084104 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 4,066E-03 0,11000133 ! elastic fiber assembly GO:0048251 5 5 0,000 4,066E-03 0,10917426 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 4,066E-03 0,10835952 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 4,066E-03 0,10755686 ! ruffle membrane GO:0032587 5 5 0,000 4,066E-03 0,106766 ! regulation of histone modification GO:0031056 5 5 0,000 4,066E-03 0,10598669 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 4,066E-03 0,10521867 ! behavioral response to pain GO:0048266 5 5 0,000 4,066E-03 0,1044617 ! clathrin coat assembly GO:0048268 6 5 0,000 4,066E-03 0,10371554 ! Notch receptor processing GO:0007220 5 5 0,000 4,066E-03 0,10297997 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 4,066E-03 0,10225476 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 4,066E-03 0,10153969 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 4,066E-03 0,10083456 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 4,066E-03 0,10013915 ! response to lipid GO:0033993 5 5 0,000 4,066E-03 0,09945326 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 4,066E-03 0,09877671 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 4,066E-03 0,0981093 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 4,066E-03 0,09745085 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 4,066E-03 0,09680117 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 4,066E-03 0,09616011 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 4,066E-03 0,09552747 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 4,066E-03 0,09490311 ! negative regulation of heart contraction GO:0045822 5 5 0,000 4,066E-03 0,09428686 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 4,066E-03 0,09367856 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 4,066E-03 0,09307805 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 4,066E-03 0,0924852 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 4,066E-03 0,09189985 ! negative regulation of endocytosis GO:0045806 5 5 0,000 4,066E-03 0,09132186 ! microfibril GO:0001527 5 5 0,000 4,066E-03 0,0907511 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 4,066E-03 0,09018743 ! toxin metabolic process GO:0009404 5 5 0,000 4,066E-03 0,08963072 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 4,066E-03 0,08908083 ! cytokine secretion GO:0050663 5 5 0,000 4,066E-03 0,08853766 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 4,066E-03 0,08800107 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 4,066E-03 0,08747094 ! skeletal myofibril assembly GO:0014866 5 5 0,000 4,066E-03 0,08694716 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 4,066E-03 0,08642962 ! epithelial cell proliferation GO:0050673 5 5 0,000 4,066E-03 0,0859182 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 4,066E-03 0,0854128 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 4,066E-03 0,08491331 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 4,066E-03 0,08441963 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 4,066E-03 0,08393165 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 4,066E-03 0,08344929 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 4,066E-03 0,08297243 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 4,066E-03 0,082501 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 4,066E-03 0,08203489 ! glutamate catabolic process GO:0006538 6 5 0,000 4,066E-03 0,08157402 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 4,066E-03 0,0811183 ! microvillus organization GO:0032528 5 5 0,000 4,066E-03 0,08066764 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 4,066E-03 0,08022197 ! L-serine biosynthetic process GO:0006564 5 5 0,000 4,066E-03 0,07978119 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 4,066E-03 0,07934522 ! pericentriolar material GO:0000242 6 5 0,000 4,066E-03 0,078914 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,066E-03 0,07848744 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 4,066E-03 0,07806546 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 4,066E-03 0,077648 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 4,066E-03 0,07723498 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 4,066E-03 0,07682633 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 4,066E-03 0,07642198 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 4,066E-03 0,07602186 ! response to tumor necrosis factor GO:0034612 6 5 0,000 4,066E-03 0,07562592 ! mRNA transcription GO:0009299 6 5 0,000 4,066E-03 0,07523407 ! response to ATP GO:0033198 5 5 0,000 4,066E-03 0,07484627 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 4,066E-03 0,07446244 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 4,066E-03 0,07408253 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 4,066E-03 0,07370648 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 4,066E-03 0,07333422 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 4,066E-03 0,07296571 ! multivesicular body GO:0005771 5 5 0,000 4,066E-03 0,07260088 ! positive regulation of transporter activity GO:0032411 5 5 0,000 4,066E-03 0,07223968 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 4,066E-03 0,07188206 ! forebrain neuron development GO:0021884 6 5 0,000 4,066E-03 0,07152796 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 4,066E-03 0,07117733 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 4,066E-03 0,07083013 ! demethylase activity GO:0032451 5 5 0,000 4,066E-03 0,07048629 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 4,066E-03 0,07014578 ! epithelial cell maturation GO:0002070 5 5 0,000 4,066E-03 0,06980854 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 4,066E-03 0,06947453 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 4,066E-03 0,0691437 ! zymogen granule GO:0042588 5 5 0,000 4,066E-03 0,068816 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 4,066E-03 0,0684914 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 4,066E-03 0,06816984 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 4,066E-03 0,06785129 ! early endosome to late endosome transport GO:0045022 5 5 0,000 4,066E-03 0,0675357 ! positive regulation of translational initiation GO:0045948 5 5 0,000 4,066E-03 0,06722304 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 4,066E-03 0,06691325 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 4,066E-03 0,06660631 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 4,066E-03 0,06630217 ! proteoglycan binding GO:0043394 9 5 0,000 4,066E-03 0,0660008 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 4,066E-03 0,06570215 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 4,066E-03 0,0654062 ! zinc ion homeostasis GO:0055069 5 5 0,000 4,066E-03 0,0651129 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 4,066E-03 0,06482221 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 4,066E-03 0,06453412 ! activated T cell proliferation GO:0050798 6 5 0,000 4,066E-03 0,06424857 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 4,066E-03 0,06396553 ! dynein binding GO:0045502 5 5 0,000 4,066E-03 0,06368498 ! regulation of dendrite development GO:0050773 5 5 0,000 4,066E-03 0,06340688 ! cardiac muscle cell development GO:0055013 5 5 0,000 4,066E-03 0,0631312 ! anterograde axon cargo transport GO:0008089 5 5 0,000 4,066E-03 0,06285791 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,066E-03 0,06258697 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 4,066E-03 0,06231835 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 4,066E-03 0,06205203 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 4,066E-03 0,06178798 ! MutLalpha complex binding GO:0032405 6 5 0,000 4,066E-03 0,06152617 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 4,066E-03 0,06126657 ! high-density lipoprotein binding GO:0008035 5 5 0,000 4,066E-03 0,06100914 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 4,066E-03 0,06075387 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 4,066E-03 0,06050073 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 4,066E-03 0,06024969 ! centromeric DNA binding GO:0019237 5 5 0,000 4,066E-03 0,06000073 ! cyclohydrolase activity GO:0019238 5 5 0,000 4,066E-03 0,05975381 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 4,066E-03 0,05950892 ! positive T cell selection GO:0043368 9 5 0,000 4,066E-03 0,05926602 ! neural tube patterning GO:0021532 5 5 0,000 4,066E-03 0,05902511 ! amylase activity GO:0016160 5 5 0,000 4,066E-03 0,05878614 ! metaphase plate congression GO:0051310 5 5 0,000 4,066E-03 0,0585491 ! regulation of sterol transport GO:0032371 5 5 0,000 4,066E-03 0,05831396 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 4,066E-03 0,0580807 ! oxygen homeostasis GO:0032364 5 5 0,000 4,066E-03 0,05784931 ! skeletal muscle regeneration GO:0043403 5 5 0,000 4,066E-03 0,05761975 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 4,066E-03 0,057392 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 4,066E-03 0,05716605 ! SAP kinase activity GO:0016909 5 5 0,000 4,066E-03 0,05694187 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 4,066E-03 0,05671944 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 4,066E-03 0,05649874 ! alpha-mannosidase activity GO:0004559 6 5 0,000 4,066E-03 0,05627975 ! alpha-glucosidase activity GO:0004558 6 5 0,000 4,066E-03 0,05606246 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 4,066E-03 0,05584683 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 4,066E-03 0,05563286 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 4,066E-03 0,05542052 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 4,066E-03 0,05520979 ! ribonuclease H activity GO:0004523 5 5 0,000 4,066E-03 0,05500067 ! CARD domain binding GO:0050700 5 5 0,000 4,066E-03 0,05479312 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 4,066E-03 0,05458713 ! AP-2 adaptor complex GO:0030122 5 5 0,000 4,066E-03 0,05438268 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 4,066E-03 0,05417976 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 4,066E-03 0,05397835 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 4,066E-03 0,05377843 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 4,066E-03 0,05357999 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 4,066E-03 0,053383 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 4,066E-03 0,05318746 ! ceramidase activity GO:0017040 5 5 0,000 4,066E-03 0,05299334 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 4,066E-03 0,05280064 ! GTP-Rho binding GO:0017049 5 5 0,000 4,066E-03 0,05260933 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 4,066E-03 0,05241941 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 4,066E-03 0,05223085 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 4,066E-03 0,05204364 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 4,066E-03 0,05185777 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 4,066E-03 0,05167322 ! TAP complex GO:0042825 5 5 0,000 4,066E-03 0,05148999 ! bHLH transcription factor binding GO:0043425 5 5 0,000 4,066E-03 0,05130804 ! actinin binding GO:0042805 6 5 0,000 4,066E-03 0,05112738 ! secretory granule organization GO:0033363 5 5 0,000 4,066E-03 0,05094799 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 4,066E-03 0,05076985 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 4,066E-03 0,05059295 ! striatum development GO:0021756 5 5 0,000 4,066E-03 0,05041728 ! photoreceptor inner segment GO:0001917 5 5 0,000 4,066E-03 0,05024282 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 4,066E-03 0,05006957 ! aldehyde-lyase activity GO:0016832 5 5 0,000 4,066E-03 0,04989751 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 4,066E-03 0,04972663 ! T cell activation during immune response GO:0002286 5 5 0,000 4,066E-03 0,04955691 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 4,066E-03 0,04938835 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 4,066E-03 0,04922094 ! dystroglycan complex GO:0016011 6 5 0,000 4,066E-03 0,04905465 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 4,066E-03 0,04888948 ! neural plate development GO:0001840 5 5 0,000 4,066E-03 0,04872542 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 4,066E-03 0,04856246 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 4,066E-03 0,04840059 ! phosphopantetheine binding GO:0031177 5 5 0,000 4,066E-03 0,04823979 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 4,066E-03 0,04808005 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 4,066E-03 0,04792137 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 4,066E-03 0,04776374 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 4,066E-03 0,04760713 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 4,066E-03 0,04745156 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 4,066E-03 0,04729699 ! retina homeostasis GO:0001895 5 5 0,000 4,066E-03 0,04714343 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 4,066E-03 0,04699086 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 4,066E-03 0,04683928 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 4,066E-03 0,04668867 ! collagen type IV GO:0005587 5 5 0,000 4,066E-03 0,04653903 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 4,066E-03 0,04639034 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 4,066E-03 0,0462426 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 4,066E-03 0,0460958 ! spindle assembly GO:0051225 5 5 0,000 4,066E-03 0,04594992 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 4,066E-03 0,04580497 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 4,066E-03 0,04566093 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 4,066E-03 0,04551779 ! protein amino acid prenylation GO:0018346 5 5 0,000 4,066E-03 0,04537555 ! stem cell division GO:0017145 5 5 0,000 4,066E-03 0,04523419 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 4,066E-03 0,04509371 ! phospholipid scrambling GO:0017121 5 5 0,000 4,066E-03 0,04495411 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 4,066E-03 0,04481536 ! regulation of humoral immune response GO:0002920 9 5 0,000 4,066E-03 0,04467746 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 4,066E-03 0,04454042 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 4,066E-03 0,04440421 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 4,066E-03 0,04426883 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 4,066E-03 0,04413427 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 4,066E-03 0,04400053 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 4,066E-03 0,0438676 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 4,066E-03 0,04373547 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 4,066E-03 0,04360413 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 4,066E-03 0,04347358 ! polyol transport GO:0015791 6 5 0,000 4,066E-03 0,04334381 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 4,066E-03 0,04321481 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 4,066E-03 0,04308658 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 4,066E-03 0,0429591 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 4,066E-03 0,04283238 ! cobalt ion transport GO:0006824 5 5 0,000 4,066E-03 0,0427064 ! response to zinc ion GO:0010043 5 5 0,000 4,066E-03 0,04258116 ! poly(U) RNA binding GO:0008266 5 5 0,000 4,066E-03 0,04245666 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 4,066E-03 0,04233287 ! adaptation of signaling pathway GO:0022401 5 5 0,000 4,066E-03 0,04220981 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 4,066E-03 0,04208747 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 4,066E-03 0,04196583 ! sensory perception of bitter taste GO:0050913 5 5 0,000 4,066E-03 0,04184489 ! regulation of dopamine uptake GO:0051584 5 5 0,000 4,066E-03 0,04172464 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 4,066E-03 0,04160509 ! protein maturation by protein folding GO:0022417 5 5 0,000 4,066E-03 0,04148622 ! neuron remodeling GO:0016322 6 5 0,000 4,066E-03 0,04136802 ! neurexin binding GO:0042043 5 5 0,000 4,066E-03 0,0412505 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 4,066E-03 0,04113364 ! regulation of potassium ion transport GO:0043266 5 5 0,000 4,066E-03 0,04101745 ! low-density lipoprotein particle GO:0034362 5 5 0,000 4,066E-03 0,0409019 ! chemoattractant activity GO:0042056 5 5 0,000 4,066E-03 0,04078701 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 4,066E-03 0,04067276 ! lipoic acid binding GO:0031405 5 5 0,000 4,066E-03 0,04055915 ! lithium ion binding GO:0031403 6 5 0,000 4,066E-03 0,04044617 ! lipoprotein particle clearance GO:0034381 5 5 0,000 4,066E-03 0,04033382 ! grooming behavior GO:0007625 5 5 0,000 4,066E-03 0,04022209 ! sequestering of actin monomers GO:0042989 5 5 0,000 4,066E-03 0,04011098 ! cobalamin binding GO:0031419 5 5 0,000 4,066E-03 0,04000049 ! retinoic acid binding GO:0001972 5 5 0,000 4,066E-03 0,03989059 ! response to axon injury GO:0048678 5 5 0,000 4,066E-03 0,0397813 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 4,066E-03 0,03967261 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 4,066E-03 0,03956451 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 4,066E-03 0,039457 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 4,066E-03 0,03935007 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 4,066E-03 0,03924372 ! female pronucleus GO:0001939 5 5 0,000 4,066E-03 0,03913794 ! F-actin capping protein complex GO:0008290 5 5 0,000 4,066E-03 0,03903273 ! DNA topoisomerase activity GO:0003916 5 5 0,000 4,066E-03 0,03892809 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 4,066E-03 0,038824 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 4,066E-03 0,03872047 ! dorsal spinal cord development GO:0021516 5 5 0,000 4,066E-03 0,03861749 ! ceramide catabolic process GO:0046514 5 5 0,000 4,066E-03 0,03851506 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 4,066E-03 0,03841316 ! neutrophil mediated immunity GO:0002446 5 5 0,000 4,066E-03 0,03831181 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 4,066E-03 0,03821099 ! Rap GTPase activator activity GO:0046582 5 5 0,000 4,066E-03 0,0381107 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 4,066E-03 0,03801093 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 4,066E-03 0,03791169 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 4,066E-03 0,03781296 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 4,066E-03 0,03771474 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 4,066E-03 0,03761704 ! neutrophil activation GO:0042119 5 5 0,000 4,066E-03 0,03751983 ! regulation of response to food GO:0032095 5 5 0,000 4,066E-03 0,03742313 ! response to food GO:0032094 5 5 0,000 4,066E-03 0,03732693 ! hedgehog receptor activity GO:0008158 5 5 0,000 4,066E-03 0,03723122 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 4,066E-03 0,037136 ! lipoprotein catabolic process GO:0042159 5 5 0,000 4,066E-03 0,03704127 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 4,066E-03 0,03694701 ! organ growth GO:0035265 7 5 0,000 4,066E-03 0,03685324 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 4,066E-03 0,03675994 ! small-subunit processome GO:0032040 5 5 0,000 4,066E-03 0,03666711 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 4,066E-03 0,03657475 ! myosin heavy chain binding GO:0032036 5 5 0,000 4,066E-03 0,03648285 ! nucleoside salvage GO:0043174 7 5 0,000 4,066E-03 0,03639142 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 4,066E-03 0,03630044 ! GPI anchor binding GO:0034235 6 5 0,000 4,066E-03 0,03620992 ! thrombin receptor activity GO:0015057 5 5 0,000 4,066E-03 0,03611984 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 4,066E-03 0,03603021 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 4,066E-03 0,03594103 ! dendritic shaft GO:0043198 5 5 0,000 4,066E-03 0,03585229 ! terminal button GO:0043195 8 5 0,000 4,066E-03 0,03576398 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 4,066E-03 0,03567611 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 4,066E-03 0,03558867 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 4,066E-03 0,03550165 ! G2/M transition checkpoint GO:0031576 5 5 0,000 4,066E-03 0,03541506 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 4,066E-03 0,0353289 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 4,066E-03 0,03524315 ! response to UV-C GO:0010225 5 5 0,000 4,066E-03 0,03515781 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 4,066E-03 0,03507289 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 4,066E-03 0,03498838 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 4,066E-03 0,03490427 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 4,066E-03 0,03482057 ! IgE binding GO:0019863 5 5 0,000 4,066E-03 0,03473726 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 4,066E-03 0,03465436 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 4,066E-03 0,03457185 ! response to cadmium ion GO:0046686 5 5 0,000 4,066E-03 0,03448973 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 4,066E-03 0,034408 ! hair follicle maturation GO:0048820 5 5 0,000 4,066E-03 0,03432666 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 4,066E-03 0,0342457 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 4,066E-03 0,03416512 ! base conversion or substitution editing GO:0016553 5 5 0,000 4,066E-03 0,03408492 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 4,066E-03 0,0340051 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 4,066E-03 0,03392565 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 4,066E-03 0,03384656 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 4,066E-03 0,03376785 ! peroxisome fission GO:0016559 5 5 0,000 4,066E-03 0,0336895 ! alpha-tubulin binding GO:0043014 5 5 0,000 4,066E-03 0,03361152 ! mitotic recombination GO:0006312 5 5 0,000 4,066E-03 0,03353389 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,066E-03 0,03345663 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 4,066E-03 0,03337972 ! positive regulation of chemokine production GO:0032722 5 5 0,000 4,066E-03 0,03330316 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,066E-03 0,03322695 ! muscle cell proliferation GO:0033002 5 5 0,000 4,066E-03 0,03315109 ! membrane to membrane docking GO:0022614 5 5 0,000 4,066E-03 0,03307557 ! translation activator activity GO:0008494 5 5 0,000 4,066E-03 0,0330004 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 4,066E-03 0,03292557 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 4,066E-03 0,03285108 ! histamine receptor activity GO:0004969 5 5 0,000 4,066E-03 0,03277692 ! dopamine receptor activity GO:0004952 5 5 0,000 4,066E-03 0,0327031 ! galactosidase activity GO:0015925 5 5 0,000 4,066E-03 0,03262961 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 4,066E-03 0,03255645 ! cellular response to nutrient GO:0031670 5 5 0,000 4,066E-03 0,03248362 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 4,066E-03 0,03241111 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 4,066E-03 0,03233892 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 4,066E-03 0,03226706 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 4,066E-03 0,03219551 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 4,066E-03 0,03212428 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 4,066E-03 0,03205337 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 4,066E-03 0,03198277 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 4,066E-03 0,03191247 ! progesterone metabolic process GO:0042448 5 5 0,000 4,066E-03 0,03184249 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 4,066E-03 0,03177281 ! disaccharide metabolic process GO:0005984 5 5 0,000 4,066E-03 0,03170344 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 4,066E-03 0,03163437 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 4,066E-03 0,0315656 ! histone acetyltransferase binding GO:0035035 5 5 0,000 4,066E-03 0,03149713 ! endosome to lysosome transport GO:0008333 5 5 0,000 4,066E-03 0,03142895 ! glial cell migration GO:0008347 5 5 0,000 4,066E-03 0,03136107 ! S-acyltransferase activity GO:0016417 5 5 0,000 4,066E-03 0,03129348 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 4,066E-03 0,03122619 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 4,066E-03 0,03115918 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 4,066E-03 0,03109245 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 4,066E-03 0,03102602 ! asparaginase activity GO:0004067 5 5 0,000 4,066E-03 0,03095986 ! insemination GO:0007320 5 5 0,000 4,066E-03 0,03089399 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 4,066E-03 0,0308284 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 4,066E-03 0,03076308 ! aminoacylase activity GO:0004046 5 5 0,000 4,066E-03 0,03069805 ! receptor biosynthetic process GO:0032800 5 5 0,000 4,066E-03 0,03063328 ! penetration of zona pellucida GO:0007341 5 5 0,000 4,066E-03 0,03056879 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 4,066E-03 0,03050457 ! aldehyde reductase activity GO:0004032 5 5 0,000 4,066E-03 0,03044062 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 4,066E-03 0,03037694 ! unconventional myosin complex GO:0016461 5 5 0,000 4,066E-03 0,03031352 ! carnitine metabolic process GO:0009437 5 5 0,000 4,066E-03 0,03025037 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 4,878E-03 0,03621145 ! regulation of helicase activity GO:0051095 6 6 0,000 4,878E-03 0,03613633 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 4,878E-03 0,03606151 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 4,878E-03 0,035987 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 4,878E-03 0,0359128 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 4,878E-03 0,03583891 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 4,878E-03 0,03576532 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 4,878E-03 0,03569203 ! ephrin receptor binding GO:0046875 7 6 0,000 4,878E-03 0,03561904 ! biotin binding GO:0009374 7 6 0,000 4,878E-03 0,03554634 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 4,878E-03 0,03547395 ! insulin receptor substrate binding GO:0043560 7 6 0,000 4,878E-03 0,03540185 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 4,878E-03 0,03533004 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 4,878E-03 0,03525852 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 4,878E-03 0,03518729 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 4,878E-03 0,03511635 ! neuron adhesion GO:0007158 6 6 0,000 4,878E-03 0,03504569 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,878E-03 0,03497532 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 4,878E-03 0,03490523 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 4,878E-03 0,03483542 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 4,878E-03 0,03476589 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 4,878E-03 0,03469663 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 4,878E-03 0,03462765 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 4,878E-03 0,03455895 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 4,878E-03 0,03449051 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 4,878E-03 0,03442235 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 4,878E-03 0,03435445 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 4,878E-03 0,03428683 ! cytoplasmic microtubule GO:0005881 7 6 0,000 4,878E-03 0,03421947 ! Arp2/3 protein complex GO:0005885 7 6 0,000 4,878E-03 0,03415237 ! neurofilament GO:0005883 6 6 0,000 4,878E-03 0,03408554 ! glial cell fate commitment GO:0021781 6 6 0,000 4,878E-03 0,03401896 ! dynactin complex GO:0005869 6 6 0,000 4,878E-03 0,03395265 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 4,878E-03 0,03388659 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 4,878E-03 0,03382079 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 4,878E-03 0,03375525 ! lipopolysaccharide binding GO:0001530 6 6 0,000 4,878E-03 0,03368996 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 4,878E-03 0,03362492 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,878E-03 0,03356013 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 4,878E-03 0,03349559 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 4,878E-03 0,0334313 ! protein lipoylation GO:0009249 6 6 0,000 4,878E-03 0,03336726 ! cysteine metabolic process GO:0006534 6 6 0,000 4,878E-03 0,03330346 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 4,878E-03 0,0332399 ! histidine catabolic process GO:0006548 6 6 0,000 4,878E-03 0,03317659 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 4,878E-03 0,03311351 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 4,878E-03 0,03305068 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 4,878E-03 0,03298808 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 4,878E-03 0,03292573 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 4,878E-03 0,0328636 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 4,878E-03 0,03280171 ! microtubule nucleation GO:0007020 6 6 0,000 4,878E-03 0,03274005 ! proline biosynthetic process GO:0006561 7 6 0,000 4,878E-03 0,03267863 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 4,878E-03 0,03261743 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 4,878E-03 0,03255646 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 4,878E-03 0,03249573 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 4,878E-03 0,03243521 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 4,878E-03 0,03237492 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 4,878E-03 0,03231486 ! paraxial mesoderm development GO:0048339 6 6 0,000 4,878E-03 0,03225502 ! melanosome organization GO:0032438 6 6 0,000 4,878E-03 0,03219539 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 4,878E-03 0,03213599 ! flotillin complex GO:0016600 6 6 0,000 4,878E-03 0,03207681 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 4,878E-03 0,03201785 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 4,878E-03 0,0319591 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 4,878E-03 0,03190057 ! positive regulation of exocytosis GO:0045921 7 6 0,000 4,878E-03 0,03184225 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 4,878E-03 0,03178414 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 4,878E-03 0,03172625 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 4,878E-03 0,03166856 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 4,878E-03 0,03161109 ! nonhomologous end joining complex GO:0070419 6 6 0,000 4,878E-03 0,03155382 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 0,000 4,878E-03 0,03149676 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! vinculin binding GO:0017166 6 6 0,000 4,878E-03 0,03143991 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 4,878E-03 0,03138326 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,878E-03 0,03132681 ! sodium ion homeostasis GO:0055078 6 6 0,000 4,878E-03 0,03127057 ! protein heterooligomerization GO:0051291 6 6 0,000 4,878E-03 0,03121453 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 4,878E-03 0,03115869 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 4,878E-03 0,03110305 ! translation termination factor activity GO:0008079 6 6 0,000 4,878E-03 0,03104761 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 4,878E-03 0,03099236 ! astrocyte development GO:0014002 6 6 0,000 4,878E-03 0,03093732 ! protein targeting to lysosome GO:0006622 6 6 0,000 4,878E-03 0,03088246 ! purine base biosynthetic process GO:0009113 7 6 0,000 4,878E-03 0,0308278 ! fibrinolysis GO:0042730 7 6 0,000 4,878E-03 0,03077334 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 4,878E-03 0,03071906 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 4,878E-03 0,03066498 ! B cell lineage commitment GO:0002326 6 6 0,000 4,878E-03 0,03061109 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 4,878E-03 0,03055738 ! response to exogenous dsRNA GO:0043330 6 6 0,000 4,878E-03 0,03050387 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 4,878E-03 0,03045054 ! melanosome transport GO:0032402 6 6 0,000 4,878E-03 0,0303974 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 4,878E-03 0,03034444 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 4,878E-03 0,03029167 ! regulation of dopamine secretion GO:0014059 6 6 0,000 4,878E-03 0,03023908 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 4,878E-03 0,03018667 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 4,878E-03 0,03013444 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,878E-03 0,0300824 ! transcription initiation factor activity GO:0016986 6 6 0,000 4,878E-03 0,03003053 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 4,878E-03 0,02997884 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 4,878E-03 0,02992733 ! Schwann cell development GO:0014044 6 6 0,000 4,878E-03 0,029876 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 4,878E-03 0,02982484 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 4,878E-03 0,02977386 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,878E-03 0,02972305 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 4,878E-03 0,02967242 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 4,878E-03 0,02962195 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 4,878E-03 0,02957166 ! nuclear envelope lumen GO:0005641 6 6 0,000 4,878E-03 0,02952154 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 4,878E-03 0,02947159 ! regulation of meiosis GO:0040020 6 6 0,000 4,878E-03 0,02942181 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 4,878E-03 0,02937219 ! lipoxygenase activity GO:0016165 6 6 0,000 4,878E-03 0,02932274 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 4,878E-03 0,02927346 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 4,878E-03 0,02922434 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 4,878E-03 0,02917539 ! DNA replication factor C complex GO:0005663 6 6 0,000 4,878E-03 0,0291266 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 4,878E-03 0,02907798 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 4,878E-03 0,02902951 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 4,878E-03 0,02898121 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 4,878E-03 0,02893307 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 4,878E-03 0,02888509 ! chromatin silencing complex GO:0005677 6 6 0,000 4,878E-03 0,02883727 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 4,878E-03 0,0287896 ! B cell homeostasis GO:0001782 7 6 0,000 4,878E-03 0,02874209 ! regulation of respiratory burst GO:0060263 6 6 0,000 4,878E-03 0,02869474 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 4,878E-03 0,02864755 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 4,878E-03 0,02860051 ! MutLalpha complex GO:0032389 6 6 0,000 4,878E-03 0,02855362 ! leading edge membrane GO:0031256 6 6 0,000 4,878E-03 0,02850689 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 4,878E-03 0,02846031 ! peptidyl-histidine modification GO:0018202 6 6 0,000 4,878E-03 0,02841388 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 4,878E-03 0,0283676 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 4,878E-03 0,02832148 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 4,878E-03 0,0282755 ! diuresis GO:0030146 6 6 0,000 4,878E-03 0,02822967 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 4,878E-03 0,02818399 ! glutathione biosynthetic process GO:0006750 6 6 0,000 4,878E-03 0,02813846 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 4,878E-03 0,02809308 ! BBSome GO:0034464 6 6 0,000 4,878E-03 0,02804784 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 4,878E-03 0,02800275 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 4,878E-03 0,0279578 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 4,878E-03 0,02791299 ! sodium channel regulator activity GO:0017080 6 6 0,000 4,878E-03 0,02786833 ! glycolipid catabolic process GO:0019377 6 6 0,000 4,878E-03 0,02782382 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 4,878E-03 0,02777944 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 4,878E-03 0,0277352 ! porphyrin catabolic process GO:0006787 8 6 0,000 4,878E-03 0,02769111 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 4,878E-03 0,02764716 ! positive regulation of glucose import GO:0046326 7 6 0,000 4,878E-03 0,02760334 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 4,878E-03 0,02755967 ! myeloid cell homeostasis GO:0002262 6 6 0,000 4,878E-03 0,02751613 ! lamin binding GO:0005521 6 6 0,000 4,878E-03 0,02747273 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 4,878E-03 0,02742946 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 4,878E-03 0,02738633 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 4,878E-03 0,02734334 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 4,878E-03 0,02730048 ! peroxiredoxin activity GO:0051920 6 6 0,000 4,878E-03 0,02725776 ! complement binding GO:0001848 8 6 0,000 4,878E-03 0,02721517 ! catecholamine transport GO:0051937 6 6 0,000 4,878E-03 0,02717271 ! regulation of sensory perception GO:0051931 6 6 0,000 4,878E-03 0,02713039 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 4,878E-03 0,02708819 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 4,878E-03 0,02704613 ! dipeptidase activity GO:0016805 6 6 0,000 4,878E-03 0,0270042 ! ether hydrolase activity GO:0016803 6 6 0,000 4,878E-03 0,0269624 ! FACIT collagen GO:0005593 6 6 0,000 4,878E-03 0,02692072 ! actin filament polymerization GO:0030041 8 6 0,000 4,878E-03 0,02687918 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 4,878E-03 0,02683776 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 4,878E-03 0,02679647 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 4,878E-03 0,02675531 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 4,878E-03 0,02671428 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 4,878E-03 0,02667337 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 4,878E-03 0,02663258 ! organ regeneration GO:0031100 6 6 0,000 4,878E-03 0,02659192 ! Golgi transport complex GO:0017119 6 6 0,000 4,878E-03 0,02655139 ! sheet-forming collagen GO:0030935 6 6 0,000 4,878E-03 0,02651097 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 4,878E-03 0,02647068 ! positive regulation of coagulation GO:0050820 7 6 0,000 4,878E-03 0,02643051 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 4,878E-03 0,02639047 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 4,878E-03 0,02635054 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 6 6 0,000 4,878E-03 0,02631074 ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 4,878E-03 0,02627105 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 4,878E-03 0,02623149 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 4,878E-03 0,02619204 ! myoblast cell fate commitment GO:0048625 6 6 0,000 4,878E-03 0,02615272 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 4,878E-03 0,02611351 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 4,878E-03 0,02607441 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 4,878E-03 0,02603544 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 4,878E-03 0,02599658 ! nuclear telomere cap complex GO:0000783 6 6 0,000 4,878E-03 0,02595784 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 4,878E-03 0,02591921 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 4,878E-03 0,0258807 ! sterol carrier activity GO:0005498 6 6 0,000 4,878E-03 0,0258423 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 4,878E-03 0,02580401 ! succinate metabolic process GO:0006105 6 6 0,000 4,878E-03 0,02576584 ! myelin sheath GO:0043209 6 6 0,000 4,878E-03 0,02572778 ! perikaryon GO:0043204 7 6 0,000 4,878E-03 0,02568984 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 4,878E-03 0,025652 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 4,878E-03 0,02561428 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 4,878E-03 0,02557666 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 4,878E-03 0,02553916 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 4,878E-03 0,02550177 ! rhythmic behavior GO:0007622 7 6 0,000 4,878E-03 0,02546449 ! copulation GO:0007620 6 6 0,000 4,878E-03 0,02542731 ! erythrocyte maturation GO:0043249 6 6 0,000 4,878E-03 0,02539025 ! equilibrioception GO:0050957 6 6 0,000 4,878E-03 0,02535329 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 4,878E-03 0,02531644 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 4,878E-03 0,02527969 ! chemosensory behavior GO:0007635 6 6 0,000 4,878E-03 0,02524306 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 4,878E-03 0,02520652 ! mechanosensory behavior GO:0007638 6 6 0,000 4,878E-03 0,0251701 ! response to interferon-gamma GO:0034341 6 6 0,000 4,878E-03 0,02513378 ! spinal cord patterning GO:0021511 6 6 0,000 4,878E-03 0,02509756 ! cGMP-mediated signaling GO:0019934 6 6 0,000 4,878E-03 0,02506145 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 4,878E-03 0,02502544 ! activation of MAPKKK activity GO:0000185 6 6 0,000 4,878E-03 0,02498954 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 4,878E-03 0,02495374 ! glucosyltransferase activity GO:0046527 6 6 0,000 4,878E-03 0,02491804 ! sphingoid catabolic process GO:0046521 6 6 0,000 4,878E-03 0,02488244 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 4,878E-03 0,02484695 ! activin receptor activity GO:0017002 6 6 0,000 4,878E-03 0,02481155 ! ovulation GO:0030728 6 6 0,000 4,878E-03 0,02477626 ! dopamine binding GO:0035240 7 6 0,000 4,878E-03 0,02474106 ! hyperosmotic response GO:0006972 6 6 0,000 4,878E-03 0,02470597 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 4,878E-03 0,02467098 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 4,878E-03 0,02463608 ! nuclear localization sequence binding GO:0008139 6 6 0,000 4,878E-03 0,02460128 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 4,878E-03 0,02456658 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 4,878E-03 0,02453198 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 4,878E-03 0,02449748 ! poly(A) RNA binding GO:0008143 6 6 0,000 4,878E-03 0,02446307 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 4,878E-03 0,02442876 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 4,878E-03 0,02439455 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 4,878E-03 0,02436043 ! intracellular pH reduction GO:0051452 6 6 0,000 4,878E-03 0,02432641 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 4,878E-03 0,02429248 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 4,878E-03 0,02425865 ! neurotrophin binding GO:0043121 6 6 0,000 4,878E-03 0,02422491 ! ciliary rootlet GO:0035253 6 6 0,000 4,878E-03 0,02419126 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 4,878E-03 0,02415771 ! ruffle organization GO:0031529 6 6 0,000 4,878E-03 0,02412425 ! T cell mediated immunity GO:0002456 6 6 0,000 4,878E-03 0,02409088 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 4,878E-03 0,02405761 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 4,878E-03 0,02402443 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 4,878E-03 0,02399133 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 4,878E-03 0,02395833 ! S-methyltransferase activity GO:0008172 6 6 0,000 4,878E-03 0,02392542 ! phospholipase D activity GO:0004630 6 6 0,000 4,878E-03 0,0238926 ! rRNA modification GO:0000154 6 6 0,000 4,878E-03 0,02385987 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 4,878E-03 0,02382723 ! neuronal ion channel clustering GO:0045161 6 6 0,000 4,878E-03 0,02379468 ! response to UV-B GO:0010224 6 6 0,000 4,878E-03 0,02376222 ! interaction with symbiont GO:0051702 6 6 0,000 4,878E-03 0,02372985 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 4,878E-03 0,02369756 ! IgG binding GO:0019864 6 6 0,000 4,878E-03 0,02366537 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 4,878E-03 0,02363325 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 4,878E-03 0,02360123 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 4,878E-03 0,02356929 ! response to copper ion GO:0046688 6 6 0,000 4,878E-03 0,02353744 ! DNA topological change GO:0006265 6 6 0,000 4,878E-03 0,02350568 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 4,878E-03 0,023474 ! dendrite morphogenesis GO:0048813 6 6 0,000 4,878E-03 0,02344241 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 4,878E-03 0,0234109 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 4,878E-03 0,02337947 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 4,878E-03 0,02334813 ! nucleosome disassembly GO:0006337 6 6 0,000 4,878E-03 0,02331688 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 4,878E-03 0,02328571 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,878E-03 0,02325462 ! guanylyltransferase activity GO:0070568 6 6 0,000 4,878E-03 0,02322361 ! receptor internalization GO:0031623 7 6 0,000 4,878E-03 0,02319269 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 4,878E-03 0,02316185 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 4,878E-03 0,02313109 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 4,878E-03 0,02310041 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 4,878E-03 0,02306981 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 4,878E-03 0,0230393 ! NuRD complex GO:0016581 6 6 0,000 4,878E-03 0,02300886 ! nucleosome positioning GO:0016584 6 6 0,000 4,878E-03 0,02297851 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 4,878E-03 0,02294823 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 4,878E-03 0,02291804 ! glycine binding GO:0016594 8 6 0,000 4,878E-03 0,02288792 ! costamere GO:0043034 7 6 0,000 4,878E-03 0,02285789 ! A band GO:0031672 6 6 0,000 4,878E-03 0,02282793 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 4,878E-03 0,02279805 ! dopamine biosynthetic process GO:0042416 7 6 0,000 4,878E-03 0,02276825 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 4,878E-03 0,02273852 ! negative regulation of axon extension GO:0030517 6 6 0,000 4,878E-03 0,02270888 ! actin monomer binding GO:0003785 6 6 0,000 4,878E-03 0,02267931 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 4,878E-03 0,02264982 ! lysozyme activity GO:0003796 6 6 0,000 4,878E-03 0,0226204 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 4,878E-03 0,02259106 ! ATP catabolic process GO:0006200 6 6 0,000 4,878E-03 0,0225618 ! determination of adult lifespan GO:0008340 6 6 0,000 4,878E-03 0,02253261 ! somatic stem cell maintenance GO:0035019 6 6 0,000 4,878E-03 0,0225035 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 4,878E-03 0,02247446 ! establishment of apical/basal cell polarity GO:0035089 6 6 0,000 4,878E-03 0,0224455 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 4,878E-03 0,02241661 ! O-acetyltransferase activity GO:0016413 6 6 0,000 4,878E-03 0,0223878 ! CoA-ligase activity GO:0016405 6 6 0,000 4,878E-03 0,02235906 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 4,878E-03 0,0223304 ! IkappaB kinase complex GO:0008385 6 6 0,000 4,878E-03 0,0223018 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 4,878E-03 0,02227328 ! store-operated calcium channel activity GO:0015279 6 6 0,000 4,878E-03 0,02224484 ! aminomethyltransferase activity GO:0004047 6 6 0,000 4,878E-03 0,02221647 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 4,878E-03 0,02218816 ! alkaline phosphatase activity GO:0004035 6 6 0,000 4,878E-03 0,02215993 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 4,878E-03 0,02213178 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 5,688E-03 0,02577802 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 5,688E-03 0,02574534 ! sleep GO:0030431 7 7 0,000 5,688E-03 0,02571276 ! synaptonemal complex assembly GO:0007130 7 7 0,000 5,688E-03 0,02568025 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 5,688E-03 0,02564782 ! cell proliferation in forebrain GO:0021846 7 7 0,000 5,688E-03 0,02561548 ! proteasome regulatory particle GO:0005838 8 7 0,000 5,688E-03 0,02558322 ! meiotic prophase I GO:0007128 7 7 0,000 5,688E-03 0,02555104 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 5,688E-03 0,02551894 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 5,688E-03 0,02548692 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 5,688E-03 0,02545498 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 5,688E-03 0,02542313 ! diphosphotransferase activity GO:0016778 8 7 0,000 5,688E-03 0,02539135 ! actin-myosin filament sliding GO:0033275 7 7 0,000 5,688E-03 0,02535965 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 5,688E-03 0,02532803 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 5,688E-03 0,02529648 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 5,688E-03 0,02526502 ! macrophage chemotaxis GO:0048246 7 7 0,000 5,688E-03 0,02523364 ! cerebral cortex cell migration GO:0021795 7 7 0,000 5,688E-03 0,02520233 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 5,688E-03 0,0251711 ! membrane hyperpolarization GO:0060081 7 7 0,000 5,688E-03 0,02513995 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 5,688E-03 0,02510887 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 5,688E-03 0,02507787 ! DNA replication origin binding GO:0003688 7 7 0,000 5,688E-03 0,02504695 ! ATPase binding GO:0051117 7 7 0,000 5,688E-03 0,0250161 ! positive regulation of glycolysis GO:0045821 7 7 0,000 5,688E-03 0,02498533 ! positive regulation of isotype switching GO:0045830 11 7 0,000 5,688E-03 0,02495464 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 5,688E-03 0,02492402 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 5,688E-03 0,02489348 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 5,688E-03 0,02486301 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 5,688E-03 0,02483261 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 5,688E-03 0,02480229 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 5,688E-03 0,02477205 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 5,688E-03 0,02474187 ! transepithelial chloride transport GO:0030321 7 7 0,000 5,688E-03 0,02471177 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 5,688E-03 0,02468175 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 5,688E-03 0,02465179 ! glycine catabolic process GO:0006546 7 7 0,000 5,688E-03 0,02462191 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 5,688E-03 0,0245921 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 5,688E-03 0,02456237 ! response to pH GO:0009268 7 7 0,000 5,688E-03 0,0245327 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,688E-03 0,02450311 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 5,688E-03 0,02447359 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 5,688E-03 0,02444414 ! endosome organization GO:0007032 7 7 0,000 5,688E-03 0,02441476 ! thyroid hormone generation GO:0006590 7 7 0,000 5,688E-03 0,02438545 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 5,688E-03 0,02435621 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 5,688E-03 0,02432704 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 5,688E-03 0,02429794 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 5,688E-03 0,02426891 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 5,688E-03 0,02423995 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 5,688E-03 0,02421106 ! retinoid X receptor binding GO:0046965 7 7 0,000 5,688E-03 0,02418223 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 5,688E-03 0,02415348 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 5,688E-03 0,02412479 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 5,688E-03 0,02409618 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 5,688E-03 0,02406763 ! urea metabolic process GO:0019627 7 7 0,000 5,688E-03 0,02403914 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 5,688E-03 0,02401073 ! regulation of type I interferon production GO:0032479 8 7 0,000 5,688E-03 0,02398238 ! peroxisomal matrix GO:0005782 7 7 0,000 5,688E-03 0,0239541 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 5,688E-03 0,02392589 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 5,688E-03 0,02389774 ! p53 binding GO:0002039 7 7 0,000 5,688E-03 0,02386966 ! osteoblast development GO:0002076 8 7 0,000 5,688E-03 0,02384164 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 5,688E-03 0,02381369 ! lipid phosphatase activity GO:0042577 7 7 0,000 5,688E-03 0,0237858 ! male sex determination GO:0030238 7 7 0,000 5,688E-03 0,02375799 ! clathrin binding GO:0030276 8 7 0,000 5,688E-03 0,02373023 ! negative regulation of translational initiation GO:0045947 7 7 0,000 5,688E-03 0,02370254 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 5,688E-03 0,02367492 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 5,688E-03 0,02364735 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 5,688E-03 0,02361986 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 5,688E-03 0,02359242 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 5,688E-03 0,02356505 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 5,688E-03 0,02353775 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 5,688E-03 0,02351051 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 5,688E-03 0,02348333 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,688E-03 0,02345621 ! protein retention in ER lumen GO:0006621 7 7 0,000 5,688E-03 0,02342915 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 5,688E-03 0,02340216 ! peptidyl-arginine modification GO:0018195 7 7 0,000 5,688E-03 0,02337523 ! regulation of circadian rhythm GO:0042752 7 7 0,000 5,688E-03 0,02334836 ! Hsp90 protein binding GO:0051879 7 7 0,000 5,688E-03 0,02332156 ! MutSalpha complex binding GO:0032407 8 7 0,000 5,688E-03 0,02329481 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 5,688E-03 0,02326813 ! establishment of melanosome localization GO:0032401 7 7 0,000 5,688E-03 0,02324151 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 5,688E-03 0,02321495 ! gas homeostasis GO:0033483 7 7 0,000 5,688E-03 0,02318844 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 5,688E-03 0,023162 ! subpallium development GO:0021544 7 7 0,000 5,688E-03 0,02313562 ! laminin-1 complex GO:0005606 7 7 0,000 5,688E-03 0,0231093 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 5,688E-03 0,02308304 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 5,688E-03 0,02305684 ! eye photoreceptor cell differentiation GO:0001754 10 7 0,000 5,688E-03 0,0230307 GO:0042462|eye photoreceptor cell development, ! T cell lineage commitment GO:0002360 7 7 0,000 5,688E-03 0,02300462 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 5,688E-03 0,02297859 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 5,688E-03 0,02295263 ! establishment of chromosome localization GO:0051303 7 7 0,000 5,688E-03 0,02292672 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 5,688E-03 0,02290088 ! regulation of cell division GO:0051302 7 7 0,000 5,688E-03 0,02287509 ! chromatin assembly complex GO:0005678 7 7 0,000 5,688E-03 0,02284936 ! sex chromatin GO:0001739 7 7 0,000 5,688E-03 0,02282368 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 5,688E-03 0,02279807 ! chitinase activity GO:0004568 7 7 0,000 5,688E-03 0,02277251 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 5,688E-03 0,02274701 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 5,688E-03 0,02272156 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 5,688E-03 0,02269618 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 5,688E-03 0,02267085 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 5,688E-03 0,02264557 ! molybdenum ion binding GO:0030151 7 7 0,000 5,688E-03 0,02262035 ! centriolar satellite GO:0034451 8 7 0,000 5,688E-03 0,02259519 ! positive regulation of epidermis development GO:0045684 7 7 0,000 5,688E-03 0,02257009 ! proteasome regulator activity GO:0010860 7 7 0,000 5,688E-03 0,02254504 ! antibiotic transport GO:0042891 7 7 0,000 5,688E-03 0,02252004 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 5,688E-03 0,0224951 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 5,688E-03 0,02247022 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 5,688E-03 0,02244539 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 5,688E-03 0,02242062 ! Wnt receptor activity GO:0042813 7 7 0,000 5,688E-03 0,0223959 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 5,688E-03 0,02237123 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 5,688E-03 0,02234662 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 5,688E-03 0,02232206 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 5,688E-03 0,02229756 ! blastocyst growth GO:0001832 7 7 0,000 5,688E-03 0,02227311 ! pigment granule transport GO:0051904 7 7 0,000 5,688E-03 0,02224872 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 5,688E-03 0,02222437 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 5,688E-03 0,02220008 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 5,688E-03 0,02217585 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 5,688E-03 0,02215167 ! cerebellar cortex formation GO:0021697 8 7 0,000 5,688E-03 0,02212754 ! activation of innate immune response GO:0002218 7 7 0,000 5,688E-03 0,02210346 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 5,688E-03 0,02207943 ! natural killer cell mediated immunity GO:0002228 7 7 0,000 5,688E-03 0,02205546 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 5,688E-03 0,02203154 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 5,688E-03 0,02200767 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 5,688E-03 0,02198385 ! regulation of muscle adaptation GO:0043502 7 7 0,000 5,688E-03 0,02196008 ! sequestering of metal ion GO:0051238 7 7 0,000 5,688E-03 0,02193637 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 5,688E-03 0,0219127 ! membrane attack complex GO:0005579 7 7 0,000 5,688E-03 0,02188909 ! fibrinogen complex GO:0005577 7 7 0,000 5,688E-03 0,02186553 ! septin complex GO:0031105 9 7 0,000 5,688E-03 0,02184202 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 5,688E-03 0,02181856 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 5,688E-03 0,02179515 ! cellular anion homeostasis GO:0030002 7 7 0,000 5,688E-03 0,02177179 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 5,688E-03 0,02174848 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 5,688E-03 0,02172522 ! autophagic vacuole formation GO:0000045 8 7 0,000 5,688E-03 0,02170201 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 5,688E-03 0,02167884 ! translation initiation factor binding GO:0031369 7 7 0,000 5,688E-03 0,02165573 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 5,688E-03 0,02163267 ! activin binding GO:0048185 7 7 0,000 5,688E-03 0,02160966 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 5,688E-03 0,02158669 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 5,688E-03 0,02156378 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 5,688E-03 0,02154091 ! phototransduction, visible light GO:0007603 7 7 0,000 5,688E-03 0,02151809 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 5,688E-03 0,02149532 ! lipoprotein transport GO:0042953 7 7 0,000 5,688E-03 0,0214726 ! cell division site part GO:0032155 7 7 0,000 5,688E-03 0,02144992 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 5,688E-03 0,0214273 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 5,688E-03 0,02140472 ! phospholipid efflux GO:0033700 7 7 0,000 5,688E-03 0,02138219 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 5,688E-03 0,0213597 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 5,688E-03 0,02133727 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 5,688E-03 0,02131488 ! poly-purine tract binding GO:0070717 7 7 0,000 5,688E-03 0,02129253 ! T-helper 1 type immune response GO:0042088 7 7 0,000 5,688E-03 0,02127024 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 5,688E-03 0,02124799 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 5,688E-03 0,02122579 ! leukocyte degranulation GO:0043299 7 7 0,000 5,688E-03 0,02120363 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 5,688E-03 0,02118152 ! bile acid and bile salt transport GO:0015721 7 7 0,000 5,688E-03 0,02115946 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 5,688E-03 0,02113744 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 5,688E-03 0,02111546 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 5,688E-03 0,02109354 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 5,688E-03 0,02107166 ! pigment granule organization GO:0048753 7 7 0,000 5,688E-03 0,02104982 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 5,688E-03 0,02102803 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 5,688E-03 0,02100628 ! regulation of pigmentation during development GO:0048070 10 7 0,000 5,688E-03 0,02098458 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 5,688E-03 0,02096293 ! macrophage activation GO:0042116 7 7 0,000 5,688E-03 0,02094132 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 5,688E-03 0,02091975 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 5,688E-03 0,02089823 ! galactose metabolic process GO:0006012 7 7 0,000 5,688E-03 0,02087675 ! vesicle fusion GO:0006906 7 7 0,000 5,688E-03 0,02085532 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 5,688E-03 0,02083393 ! glycerol ether catabolic process GO:0044269 7 7 0,000 5,688E-03 0,02081258 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 5,688E-03 0,02079128 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 5,688E-03 0,02077002 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 5,688E-03 0,0207488 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 5,688E-03 0,02072763 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 5,688E-03 0,0207065 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 5,688E-03 0,02068541 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 5,688E-03 0,02066437 ! inclusion body GO:0016234 7 7 0,000 5,688E-03 0,02064337 ! parturition GO:0007567 7 7 0,000 5,688E-03 0,02062241 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 5,688E-03 0,0206015 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 5,688E-03 0,02058063 ! intercalated disc GO:0014704 8 7 0,000 5,688E-03 0,02055979 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 5,688E-03 0,02053901 ! neural nucleus development GO:0048857 7 7 0,000 5,688E-03 0,02051826 ! intermediate filament organization GO:0045109 8 7 0,000 5,688E-03 0,02049756 ! skeletal muscle contraction GO:0003009 7 7 0,000 5,688E-03 0,02047689 ! response to antibiotic GO:0046677 7 7 0,000 5,688E-03 0,02045627 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 5,688E-03 0,02043569 ! preribosome GO:0030684 7 7 0,000 5,688E-03 0,02041515 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 5,688E-03 0,02039466 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 5,688E-03 0,0203742 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 5,688E-03 0,02035378 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 5,688E-03 0,02033341 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 5,688E-03 0,02031308 ! postreplication repair GO:0006301 7 7 0,000 5,688E-03 0,02029278 ! gap junction channel activity GO:0005243 7 7 0,000 5,688E-03 0,02027253 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 5,688E-03 0,02025232 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 5,688E-03 0,02023215 ! transcription termination GO:0006353 8 7 0,000 5,688E-03 0,02021202 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 5,688E-03 0,02019193 ! tetracycline transporter activity GO:0008493 7 7 0,000 5,688E-03 0,02017187 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 5,688E-03 0,02015186 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 5,688E-03 0,02013189 ! melanocortin receptor activity GO:0004977 7 7 0,000 5,688E-03 0,02011196 ! coenzyme A metabolic process GO:0015936 8 7 0,000 5,688E-03 0,02009206 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 5,688E-03 0,02007221 ! regulation of macrophage activation GO:0043030 7 7 0,000 5,688E-03 0,0200524 ! cytidine deaminase activity GO:0004126 7 7 0,000 5,688E-03 0,02003262 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 5,688E-03 0,02001288 ! apical protein localization GO:0045176 7 7 0,000 5,688E-03 0,01999319 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 5,688E-03 0,01997353 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 5,688E-03 0,01995391 ! virion binding GO:0046790 10 7 0,000 5,688E-03 0,01993433 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 5,688E-03 0,01991478 ! protein prenyltransferase activity GO:0008318 7 7 0,000 5,688E-03 0,01989528 ! protein modification by small protein removal GO:0070646 7 7 0,000 5,688E-03 0,01987581 ! adult feeding behavior GO:0008343 7 7 0,000 5,688E-03 0,01985638 ! CoA carboxylase activity GO:0016421 7 7 0,000 5,688E-03 0,01983699 ! microtubule basal body GO:0005932 7 7 0,000 5,688E-03 0,01981764 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 5,688E-03 0,01979832 ! embryonic heart tube development GO:0035050 7 7 0,000 5,688E-03 0,01977904 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 5,688E-03 0,0197598 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 5,688E-03 0,0197406 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 5,688E-03 0,01972143 ! rRNA transcription GO:0009303 8 8 0,000 6,499E-03 0,02250852 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 6,499E-03 0,02248671 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 6,499E-03 0,02246494 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 6,499E-03 0,02244321 GO:0005451|monovalent cation:hydrogen antiporter activity, ! negative regulation of lipid biosynthetic process GO:0051055 9 8 0,000 6,499E-03 0,02242153 ! cation:chloride symporter activity GO:0015377 9 8 0,000 6,499E-03 0,02239989 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 6,499E-03 0,02237829 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 6,499E-03 0,02235673 ! male meiosis GO:0007140 8 8 0,000 6,499E-03 0,02233521 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 6,499E-03 0,02231373 ! N-glycan processing GO:0006491 8 8 0,000 6,499E-03 0,0222923 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 6,499E-03 0,02227091 ! protein self-association GO:0043621 8 8 0,000 6,499E-03 0,02224955 ! RNA methylation GO:0001510 8 8 0,000 6,499E-03 0,02222824 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 6,499E-03 0,02220697 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 6,499E-03 0,02218574 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 6,499E-03 0,02216455 ! hexokinase activity GO:0004396 8 8 0,000 6,499E-03 0,0221434 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 6,499E-03 0,02212229 ! guanylate cyclase activity GO:0004383 8 8 0,000 6,499E-03 0,02210122 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 6,499E-03 0,02208019 ! troponin complex GO:0005861 9 8 0,000 6,499E-03 0,0220592 ! smoothened signaling pathway GO:0007224 8 8 0,000 6,499E-03 0,02203826 ! keratinocyte proliferation GO:0043616 8 8 0,000 6,499E-03 0,02201735 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 6,499E-03 0,02199648 ! ganglioside metabolic process GO:0001573 8 8 0,000 6,499E-03 0,02197565 ! reflex GO:0060004 11 8 0,000 6,499E-03 0,02195486 ! small protein activating enzyme activity GO:0008641 10 8 0,000 6,499E-03 0,0219341 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 6,499E-03 0,02191339 ! hemoglobin metabolic process GO:0020027 8 8 0,000 6,499E-03 0,02189272 ! protein targeting to ER GO:0045047 9 8 0,000 6,499E-03 0,02187209 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 6,499E-03 0,02185149 ! arginine catabolic process GO:0006527 8 8 0,000 6,499E-03 0,02183093 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 6,499E-03 0,02181042 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 6,499E-03 0,02178994 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 6,499E-03 0,0217695 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 6,499E-03 0,02174909 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 6,499E-03 0,02172873 ! proline metabolic process GO:0006560 9 8 0,000 6,499E-03 0,0217084 ! melanosome membrane GO:0033162 10 8 0,000 6,499E-03 0,02168812 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 6,499E-03 0,02166786 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 6,499E-03 0,02164765 ! melanin metabolic process GO:0006582 9 8 0,000 6,499E-03 0,02162748 ! death receptor activity GO:0005035 8 8 0,000 6,499E-03 0,02160734 ! Golgi lumen GO:0005796 8 8 0,000 6,499E-03 0,02158724 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 6,499E-03 0,02156718 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 6,499E-03 0,02154715 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 6,499E-03 0,02152716 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 6,499E-03 0,02150721 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 6,499E-03 0,0214873 ! Rac protein signal transduction GO:0016601 8 8 0,000 6,499E-03 0,02146742 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 6,499E-03 0,02144758 ! lens development in camera-type eye GO:0002088 8 8 0,000 6,499E-03 0,02142778 ! positive regulation of vasodilation GO:0045909 8 8 0,000 6,499E-03 0,02140801 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 6,499E-03 0,02138828 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 6,499E-03 0,02136858 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 6,499E-03 0,02134893 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 6,499E-03 0,0213293 ! Schwann cell differentiation GO:0014037 8 8 0,000 6,499E-03 0,02130972 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 6,499E-03 0,02129017 ! axon guidance receptor activity GO:0008046 8 8 0,000 6,499E-03 0,02127065 ! protein targeting to vacuole GO:0006623 8 8 0,000 6,499E-03 0,02125117 ! response to tropane GO:0014073 10 8 0,000 6,499E-03 0,02123173 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 6,499E-03 0,02121232 ! melanosome localization GO:0032400 8 8 0,000 6,499E-03 0,02119295 ! response to amine stimulus GO:0014075 10 8 0,000 6,499E-03 0,02117362 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 6,499E-03 0,02115431 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 6,499E-03 0,02113505 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 6,499E-03 0,02111582 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 6,499E-03 0,02109662 ! holo TFIIH complex GO:0005675 8 8 0,000 6,499E-03 0,02107746 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 6,499E-03 0,02105833 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 6,499E-03 0,02103924 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 6,499E-03 0,02102018 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 6,499E-03 0,02100116 ! vitamin transporter activity GO:0051183 8 8 0,000 6,499E-03 0,02098217 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 6,499E-03 0,02096322 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 6,499E-03 0,0209443 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 6,499E-03 0,02092541 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 6,499E-03 0,02090656 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 6,499E-03 0,02088774 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 6,499E-03 0,02086896 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 6,499E-03 0,02085021 ! regulation of synaptogenesis GO:0051963 8 8 0,000 6,499E-03 0,02083149 ! oocyte differentiation GO:0009994 8 8 0,000 6,499E-03 0,02081281 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 6,499E-03 0,02079416 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 6,499E-03 0,02077554 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 6,499E-03 0,02075696 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 6,499E-03 0,02073841 ! establishment of pigment granule localization GO:0051905 8 8 0,000 6,499E-03 0,0207199 ! regulation of telomere maintenance GO:0032204 8 8 0,000 6,499E-03 0,02070141 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 6,499E-03 0,02068296 ! amino sugar catabolic process GO:0046348 8 8 0,000 6,499E-03 0,02066454 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 6,499E-03 0,02064616 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 6,499E-03 0,02062781 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 6,499E-03 0,02060949 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 6,499E-03 0,0205912 ! cholesterol transporter activity GO:0017127 8 8 0,000 6,499E-03 0,02057295 ! GABA receptor binding GO:0050811 8 8 0,000 6,499E-03 0,02055472 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 6,499E-03 0,02053653 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 6,499E-03 0,02051838 ! regulation of developmental growth GO:0048638 8 8 0,000 6,499E-03 0,02050025 ! GMP binding GO:0019002 10 8 0,000 6,499E-03 0,02048216 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 6,499E-03 0,02046409 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 6,499E-03 0,02044606 ! prostate gland development GO:0030850 8 8 0,000 6,499E-03 0,02042807 ! 7S RNA binding GO:0008312 9 8 0,000 6,499E-03 0,0204101 ! phosphate transport GO:0006817 9 8 0,000 6,499E-03 0,02039216 ! neutral lipid catabolic process GO:0046461 8 8 0,000 6,499E-03 0,02037426 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 6,499E-03 0,02035639 ! reproductive behavior GO:0019098 8 8 0,000 6,499E-03 0,02033855 ! cell volume homeostasis GO:0006884 9 8 0,000 6,499E-03 0,02032074 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 6,499E-03 0,02030296 ! oligopeptide transport GO:0006857 8 8 0,000 6,499E-03 0,02028521 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 6,499E-03 0,0202675 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 6,499E-03 0,02024981 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 6,499E-03 0,02023216 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 6,499E-03 0,02021453 ! titin binding GO:0031432 8 8 0,000 6,499E-03 0,02019694 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 6,499E-03 0,02017938 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 6,499E-03 0,02016184 ! bone resorption GO:0045453 8 8 0,000 6,499E-03 0,02014434 ! glycerolipid catabolic process GO:0046503 8 8 0,000 6,499E-03 0,02012687 ! endoderm development GO:0007492 8 8 0,000 6,499E-03 0,02010943 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 6,499E-03 0,02009202 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 6,499E-03 0,02007464 ! astrocyte differentiation GO:0048708 8 8 0,000 6,499E-03 0,02005729 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 6,499E-03 0,02003997 ! syncytium formation GO:0006949 8 8 0,000 6,499E-03 0,02002268 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 6,499E-03 0,02000542 ! B cell proliferation GO:0042100 8 8 0,000 6,499E-03 0,01998819 ! mannose metabolic process GO:0006013 10 8 0,000 6,499E-03 0,01997098 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 6,499E-03 0,01995381 ! asymmetric protein localization GO:0008105 8 8 0,000 6,499E-03 0,01993667 ! tumor necrosis factor binding GO:0043120 8 8 0,000 6,499E-03 0,01991956 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 6,499E-03 0,01990247 ! neuron apoptosis GO:0051402 8 8 0,000 6,499E-03 0,01988542 ! macroautophagy GO:0016236 9 8 0,000 6,499E-03 0,01986839 ! Cajal body GO:0015030 8 8 0,000 6,499E-03 0,0198514 ! O-methyltransferase activity GO:0008171 9 8 0,000 6,499E-03 0,01983443 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 6,499E-03 0,01981749 ! PcG protein complex GO:0031519 8 8 0,000 6,499E-03 0,01980058 ! ferric iron binding GO:0008199 9 8 0,000 6,499E-03 0,0197837 ! spindle checkpoint GO:0031577 8 8 0,000 6,499E-03 0,01976685 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 6,499E-03 0,01975003 ! segment specification GO:0007379 8 8 0,000 6,499E-03 0,01973323 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 6,499E-03 0,01971647 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 6,499E-03 0,01969973 ! cellular extravasation GO:0045123 9 8 0,000 6,499E-03 0,01968302 ! pronucleus GO:0045120 8 8 0,000 6,499E-03 0,01966634 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 6,499E-03 0,01964969 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 6,499E-03 0,01963307 ! Rac GTPase activator activity GO:0030675 9 8 0,000 6,499E-03 0,01961647 ! regulation of DNA repair GO:0006282 8 8 0,000 6,499E-03 0,0195999 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 6,499E-03 0,01958336 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 6,499E-03 0,01956685 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 6,499E-03 0,01955036 ! DNA ligation GO:0006266 8 8 0,000 6,499E-03 0,01953391 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 6,499E-03 0,01951748 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 6,499E-03 0,01950108 ! multicellular organismal aging GO:0010259 8 8 0,000 6,499E-03 0,0194847 ! erythrocyte development GO:0048821 8 8 0,000 6,499E-03 0,01946836 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 6,499E-03 0,01945204 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 6,499E-03 0,01943575 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 6,499E-03 0,01941948 ! gamma-tubulin binding GO:0043015 8 8 0,000 6,499E-03 0,01940325 ! ribosome binding GO:0043022 9 8 0,000 6,499E-03 0,01938704 ! NADPH oxidase complex GO:0043020 8 8 0,000 6,499E-03 0,01937085 ! mRNA polyadenylation GO:0006378 8 8 0,000 6,499E-03 0,0193547 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 6,499E-03 0,01933857 ! adenylyltransferase activity GO:0070566 8 8 0,000 6,499E-03 0,01932247 ! zymogen activation GO:0031638 8 8 0,000 6,499E-03 0,01930639 ! axonal fasciculation GO:0007413 8 8 0,000 6,499E-03 0,01929034 ! negative regulation of nuclear division GO:0051784 8 8 0,000 6,499E-03 0,01927432 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 6,499E-03 0,01925833 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 6,499E-03 0,01924236 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 6,499E-03 0,01922642 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 6,499E-03 0,0192105 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 6,499E-03 0,01919461 ! wide pore channel activity GO:0022829 8 8 0,000 6,499E-03 0,01917875 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 6,499E-03 0,01916291 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 6,499E-03 0,0191471 ! hormone catabolic process GO:0042447 8 8 0,000 6,499E-03 0,01913131 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 6,499E-03 0,01911555 ! biogenic amine catabolic process GO:0042402 11 8 0,000 6,499E-03 0,01909982 ! Notch binding GO:0005112 8 8 0,000 6,499E-03 0,01908411 ! death receptor binding GO:0005123 8 8 0,000 6,499E-03 0,01906843 ! ATPase regulator activity GO:0060590 8 8 0,000 6,499E-03 0,01905278 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 6,499E-03 0,01903715 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 6,499E-03 0,01902154 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 6,499E-03 0,01900596 ! calcium-release channel activity GO:0015278 8 8 0,000 6,499E-03 0,01899041 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 6,499E-03 0,01897488 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 6,499E-03 0,01895938 ! nucleus localization GO:0051647 10 8 0,000 6,499E-03 0,0189439 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 6,499E-03 0,01892845 ! negative regulation of immune effector process GO:0002698 12 8 0,000 6,499E-03 0,01891303 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 6,499E-03 0,01889762 ! adenosine deaminase activity GO:0004000 8 8 0,000 6,499E-03 0,01888225 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 7,308E-03 0,02121734 ! respiratory burst GO:0045730 9 9 0,000 7,308E-03 0,0212001 ! telencephalon cell migration GO:0022029 9 9 0,000 7,308E-03 0,0211829 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 7,308E-03 0,02116572 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 7,308E-03 0,02114856 ! cGMP metabolic process GO:0046068 9 9 0,000 7,308E-03 0,02113144 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 7,308E-03 0,02111434 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 7,308E-03 0,02109727 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 7,308E-03 0,02108023 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 7,308E-03 0,02106322 ! RNA polyadenylation GO:0043631 9 9 0,000 7,308E-03 0,02104623 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 7,308E-03 0,02102927 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 7,308E-03 0,02101234 ! artery development GO:0060840 9 9 0,000 7,308E-03 0,02099544 GO:0048844|artery morphogenesis, ! photoreceptor cell development GO:0042461 12 9 0,000 7,308E-03 0,02097856 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 0,000 7,308E-03 0,02096171 ! middle ear morphogenesis GO:0042474 9 9 0,000 7,308E-03 0,02094489 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 7,308E-03 0,02092809 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 7,308E-03 0,02091132 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 7,308E-03 0,02089458 ! lung alveolus development GO:0048286 9 9 0,000 7,308E-03 0,02087786 ! ciliary or flagellar motility GO:0001539 9 9 0,000 7,308E-03 0,02086117 ! beta-amyloid binding GO:0001540 10 9 0,000 7,308E-03 0,02084451 ! pathogenesis GO:0009405 9 9 0,000 7,308E-03 0,02082788 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 7,308E-03 0,02081127 ! regulated secretory pathway GO:0045055 9 9 0,000 7,308E-03 0,02079468 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 7,308E-03 0,02077813 ! estrogen receptor binding GO:0030331 9 9 0,000 7,308E-03 0,0207616 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 7,308E-03 0,02074509 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 7,308E-03 0,02072862 ! histidine metabolic process GO:0006547 9 9 0,000 7,308E-03 0,02071216 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 7,308E-03 0,02069574 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 7,308E-03 0,02067934 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 7,308E-03 0,02066297 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 7,308E-03 0,02064662 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 7,308E-03 0,0206303 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 7,308E-03 0,020614 ! entry into host cell GO:0030260 9 9 0,000 7,308E-03 0,02059773 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 7,308E-03 0,02058149 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 7,308E-03 0,02056527 ! retinoic acid metabolic process GO:0042573 9 9 0,000 7,308E-03 0,02054908 ! retinol metabolic process GO:0042572 9 9 0,000 7,308E-03 0,02053291 ! behavioral fear response GO:0001662 9 9 0,000 7,308E-03 0,02051677 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 7,308E-03 0,02050065 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 7,308E-03 0,02048456 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 7,308E-03 0,02046849 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 7,308E-03 0,02045245 ! regulation of gliogenesis GO:0014013 9 9 0,000 7,308E-03 0,02043644 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 7,308E-03 0,02042044 ! pigment granule localization GO:0051875 9 9 0,000 7,308E-03 0,02040448 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 7,308E-03 0,02038854 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 7,308E-03 0,02037262 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 7,308E-03 0,02035673 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 7,308E-03 0,02034086 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 7,308E-03 0,02032502 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 7,308E-03 0,0203092 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 7,308E-03 0,02029341 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 7,308E-03 0,02027764 ! nitric oxide metabolic process GO:0046209 9 9 0,000 7,308E-03 0,0202619 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 7,308E-03 0,02024618 ! icosanoid secretion GO:0032309 9 9 0,000 7,308E-03 0,02023049 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 7,308E-03 0,02021482 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 7,308E-03 0,02019917 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 7,308E-03 0,02018355 ! sterol catabolic process GO:0016127 9 9 0,000 7,308E-03 0,02016795 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 7,308E-03 0,02015238 ! peptidyl-lysine modification GO:0018205 9 9 0,000 7,308E-03 0,02013683 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 7,308E-03 0,0201213 ! clathrin coat of coated pit GO:0030132 12 9 0,000 7,308E-03 0,0201058 ! SNARE complex GO:0031201 10 9 0,000 7,308E-03 0,02009032 ! ubiquinone metabolic process GO:0006743 10 9 0,000 7,308E-03 0,02007487 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 7,308E-03 0,02005944 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 7,308E-03 0,02004403 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 7,308E-03 0,02002865 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 7,308E-03 0,02001329 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 7,308E-03 0,01999795 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,308E-03 0,01998264 ! peptidoglycan binding GO:0042834 9 9 0,000 7,308E-03 0,01996735 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 7,308E-03 0,01995209 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 7,308E-03 0,01993684 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 7,308E-03 0,01992162 ! cholesterol efflux GO:0033344 9 9 0,000 7,308E-03 0,01990643 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 7,308E-03 0,01989126 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 7,308E-03 0,01987611 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! leukocyte mediated cytotoxicity GO:0001909 9 9 0,000 7,308E-03 0,01986098 ! anterior/posterior axis specification GO:0009948 9 9 0,000 7,308E-03 0,01984588 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 7,308E-03 0,0198308 ! detection of calcium ion GO:0005513 10 9 0,000 7,308E-03 0,01981574 ! negative regulation of glucose import GO:0046325 9 9 0,000 7,308E-03 0,0198007 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 7,308E-03 0,01978569 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 7,308E-03 0,0197707 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 7,308E-03 0,01975574 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 7,308E-03 0,01974079 ! desmosome GO:0030057 9 9 0,000 7,308E-03 0,01972587 ! prepulse inhibition GO:0060134 9 9 0,000 7,308E-03 0,01971097 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 7,308E-03 0,0196961 ! negative regulation of B cell activation GO:0050869 9 9 0,000 7,308E-03 0,01968124 ! anchoring collagen GO:0030934 9 9 0,000 7,308E-03 0,01966641 ! axon extension GO:0048675 10 9 0,000 7,308E-03 0,0196516 ! neuron fate specification GO:0048665 9 9 0,000 7,308E-03 0,01963682 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 7,308E-03 0,01962205 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 7,308E-03 0,01960731 ! virus-host interaction GO:0019048 13 9 0,000 7,308E-03 0,01959259 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 7,308E-03 0,01957789 ! pentose-phosphate shunt GO:0006098 9 9 0,000 7,308E-03 0,01956321 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 7,308E-03 0,01954856 ! DNA bending activity GO:0008301 9 9 0,000 7,308E-03 0,01953393 ! social behavior GO:0035176 9 9 0,000 7,308E-03 0,01951932 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 7,308E-03 0,01950473 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 7,308E-03 0,01949016 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 7,308E-03 0,01947562 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 7,308E-03 0,01946109 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 7,308E-03 0,01944659 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 7,308E-03 0,01943211 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 7,308E-03 0,01941765 ! blood vessel remodeling GO:0001974 10 9 0,000 7,308E-03 0,01940322 ! C-X-C chemokine binding GO:0019958 9 9 0,000 7,308E-03 0,0193888 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 7,308E-03 0,01937441 ! exosome (RNase complex) GO:0000178 9 9 0,000 7,308E-03 0,01936004 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 7,308E-03 0,01934568 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 7,308E-03 0,01933135 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 7,308E-03 0,01931705 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 7,308E-03 0,01930276 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 7,308E-03 0,01928849 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 7,308E-03 0,01927425 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 7,308E-03 0,01926002 ! phagocytosis, engulfment GO:0006911 10 9 0,000 7,308E-03 0,01924582 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 7,308E-03 0,01923163 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 7,308E-03 0,01921747 ! glutathione peroxidase activity GO:0004602 9 9 0,000 7,308E-03 0,01920333 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 7,308E-03 0,01918921 ! lysophospholipase activity GO:0004622 9 9 0,000 7,308E-03 0,01917511 ! brain morphogenesis GO:0048854 9 9 0,000 7,308E-03 0,01916103 ! apolipoprotein binding GO:0034185 9 9 0,000 7,308E-03 0,01914698 ! synaptic vesicle membrane GO:0030672 9 9 0,000 7,308E-03 0,01913294 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 7,308E-03 0,01911892 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 7,308E-03 0,01910493 ! kinesin binding GO:0019894 9 9 0,000 7,308E-03 0,01909095 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 7,308E-03 0,01907699 ! renal water homeostasis GO:0003091 9 9 0,000 7,308E-03 0,01906306 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 7,308E-03 0,01904914 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 7,308E-03 0,01903525 ! histone methylation GO:0016571 10 9 0,000 7,308E-03 0,01902138 ! mRNA cleavage GO:0006379 9 9 0,000 7,308E-03 0,01900752 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 7,308E-03 0,01899369 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 0,000 7,308E-03 0,01897987 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 7,308E-03 0,01896608 ! opioid receptor activity GO:0004985 9 9 0,000 7,308E-03 0,01895231 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 7,308E-03 0,01893855 ! salivary gland development GO:0007431 10 9 0,000 7,308E-03 0,01892482 ! glucosidase activity GO:0015926 10 9 0,000 7,308E-03 0,01891111 ! adrenoceptor activity GO:0004935 11 9 0,000 7,308E-03 0,01889741 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 0,000 7,308E-03 0,01888374 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 7,308E-03 0,01887009 ! purine base metabolic process GO:0006144 11 9 0,000 7,308E-03 0,01885645 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 7,308E-03 0,01884284 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 7,308E-03 0,01882924 ! receptor inhibitor activity GO:0030547 9 9 0,000 7,308E-03 0,01881567 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 7,308E-03 0,01880211 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 7,308E-03 0,01878857 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 7,308E-03 0,01877506 ! palmitoyltransferase activity GO:0016409 9 9 0,000 7,308E-03 0,01876156 ! arylsulfatase activity GO:0004065 9 9 0,000 7,308E-03 0,01874808 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 7,308E-03 0,01873462 ! behavioral response to nicotine GO:0035095 9 9 0,000 7,308E-03 0,01872118 ! adenylate kinase activity GO:0004017 10 9 0,000 7,308E-03 0,01870776 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 7,308E-03 0,01869436 ! mitochondrion localization GO:0051646 9 9 0,000 7,308E-03 0,01868098 ! localization within membrane GO:0051668 9 9 0,000 7,308E-03 0,01866762 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 8,117E-03 0,02071924 ! lipid particle GO:0005811 10 10 0,000 8,117E-03 0,02070444 ! myotube differentiation GO:0014902 10 10 0,000 8,117E-03 0,02068966 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 8,117E-03 0,0206749 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 8,117E-03 0,02066017 ! synapsis GO:0007129 10 10 0,000 8,117E-03 0,02064545 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 8,117E-03 0,02063076 ! UTP metabolic process GO:0046051 10 10 0,000 8,117E-03 0,02061608 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 8,117E-03 0,02060143 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 8,117E-03 0,0205868 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 8,117E-03 0,02057219 ! platelet alpha granule membrane GO:0031092 11 10 0,000 8,117E-03 0,0205576 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 8,117E-03 0,02054303 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 8,117E-03 0,02052848 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 8,117E-03 0,02051395 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 8,117E-03 0,02049944 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 8,117E-03 0,02048496 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 8,117E-03 0,02047049 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 8,117E-03 0,02045604 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 8,117E-03 0,02044162 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 8,117E-03 0,02042721 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 8,117E-03 0,02041283 ! melanocyte differentiation GO:0030318 10 10 0,000 8,117E-03 0,02039846 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 8,117E-03 0,02038412 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 8,117E-03 0,02036979 ! L-serine metabolic process GO:0006563 11 10 0,000 8,117E-03 0,02035549 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 8,117E-03 0,0203412 ! lipase inhibitor activity GO:0055102 10 10 0,000 8,117E-03 0,02032694 ! autophagic vacuole GO:0005776 11 10 0,000 8,117E-03 0,02031269 ! NAD metabolic process GO:0019674 10 10 0,000 8,117E-03 0,02029847 ! stereocilium GO:0032420 10 10 0,000 8,117E-03 0,02028426 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 8,117E-03 0,02027008 ! regulation of sodium ion transport GO:0002028 10 10 0,000 8,117E-03 0,02025591 ! forebrain cell migration GO:0021885 10 10 0,000 8,117E-03 0,02024177 ! organelle subcompartment GO:0031984 11 10 0,000 8,117E-03 0,02022764 ! chondrocyte differentiation GO:0002062 10 10 0,000 8,117E-03 0,02021354 ! negative regulation of ossification GO:0030279 10 10 0,000 8,117E-03 0,02019945 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 8,117E-03 0,02018538 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 8,117E-03 0,02017134 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 8,117E-03 0,02015731 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 8,117E-03 0,0201433 ! protein homotetramerization GO:0051289 11 10 0,000 8,117E-03 0,02012931 ! regulation of dephosphorylation GO:0035303 12 10 0,000 8,117E-03 0,02011535 ! oligodendrocyte development GO:0014003 10 10 0,000 8,117E-03 0,0201014 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 8,117E-03 0,02008747 ! response to dsRNA GO:0043331 10 10 0,000 8,117E-03 0,02007355 ! mismatch repair complex binding GO:0032404 11 10 0,000 8,117E-03 0,02005966 ! snRNA metabolic process GO:0016073 10 10 0,000 8,117E-03 0,02004579 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 8,117E-03 0,02003194 ! fucose catabolic process GO:0019317 11 10 0,000 8,117E-03 0,0200181 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 8,117E-03 0,02000429 ! retinal binding GO:0016918 10 10 0,000 8,117E-03 0,01999049 ! leukocyte activation during immune response GO:0002366 10 10 0,000 8,117E-03 0,01997671 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 8,117E-03 0,01996296 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 8,117E-03 0,01994922 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 8,117E-03 0,0199355 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 8,117E-03 0,0199218 ! ribonuclease P activity GO:0004526 10 10 0,000 8,117E-03 0,01990811 ! midbrain development GO:0030901 10 10 0,000 8,117E-03 0,01989445 ! musculoskeletal movement GO:0050881 10 10 0,000 8,117E-03 0,0198808 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 8,117E-03 0,01986718 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 8,117E-03 0,01985357 ! fatty-acid ligase activity GO:0015645 10 10 0,000 8,117E-03 0,01983998 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 8,117E-03 0,01982641 ! quaternary ammonium group transport GO:0015697 10 10 0,000 8,117E-03 0,01981286 ! regulation of RNA splicing GO:0043484 10 10 0,000 8,117E-03 0,01979933 ! embryonic gut development GO:0048566 10 10 0,000 8,117E-03 0,01978581 ! positive regulation of amine transport GO:0051954 10 10 0,000 8,117E-03 0,01977231 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 8,117E-03 0,01975884 ! mRNA 3'-end processing GO:0031124 10 10 0,000 8,117E-03 0,01974538 ! lysogeny GO:0030069 10 10 0,000 8,117E-03 0,01973194 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 8,117E-03 0,01971851 ! establishment of cell polarity GO:0030010 10 10 0,000 8,117E-03 0,01970511 ! regulation of synapse organization GO:0050807 10 10 0,000 8,117E-03 0,01969172 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 8,117E-03 0,01967835 ! acyl-CoA binding GO:0000062 10 10 0,000 8,117E-03 0,019665 ! negative regulation of muscle development GO:0048635 11 10 0,000 8,117E-03 0,01965167 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 8,117E-03 0,01963836 ! GDP binding GO:0019003 10 10 0,000 8,117E-03 0,01962506 ! photoreceptor activity GO:0009881 10 10 0,000 8,117E-03 0,01961178 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 8,117E-03 0,01959852 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 8,117E-03 0,01958528 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 8,117E-03 0,01957205 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 8,117E-03 0,01955885 ! nucleotidase activity GO:0008252 10 10 0,000 8,117E-03 0,01954566 ! detection of mechanical stimulus GO:0050982 10 10 0,000 8,117E-03 0,01953249 ! protein complex disassembly GO:0043241 11 10 0,000 8,117E-03 0,01951934 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 8,117E-03 0,0195062 ! lateral plasma membrane GO:0016328 10 10 0,000 8,117E-03 0,01949308 ! estrogen metabolic process GO:0008210 10 10 0,000 8,117E-03 0,01947998 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 8,117E-03 0,0194669 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 8,117E-03 0,01945383 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 8,117E-03 0,01944079 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 8,117E-03 0,01942776 ! interleukin-1 binding GO:0019966 10 10 0,000 8,117E-03 0,01941474 ! endothelial cell differentiation GO:0045446 10 10 0,000 8,117E-03 0,01940175 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 8,117E-03 0,01938877 ! acid phosphatase activity GO:0003993 10 10 0,000 8,117E-03 0,01937581 ! regulation of stress fiber formation GO:0051492 13 10 0,000 8,117E-03 0,01936287 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 8,117E-03 0,01934994 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 8,117E-03 0,01933703 ! telomeric DNA binding GO:0042162 11 10 0,000 8,117E-03 0,01932414 ! regulation of intracellular pH GO:0051453 10 10 0,000 8,117E-03 0,01931127 ! lipid digestion GO:0044241 10 10 0,000 8,117E-03 0,01929841 ! multicellular organism growth GO:0035264 10 10 0,000 8,117E-03 0,01928557 ! receptor clustering GO:0043113 10 10 0,000 8,117E-03 0,01927275 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 8,117E-03 0,01925994 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 8,117E-03 0,01924715 ! adult heart development GO:0007512 12 10 0,000 8,117E-03 0,01923438 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 8,117E-03 0,01922163 ! signalosome GO:0008180 10 10 0,000 8,117E-03 0,01920889 ! prefoldin complex GO:0016272 10 10 0,000 8,117E-03 0,01919617 ! neuromuscular junction GO:0031594 10 10 0,000 8,117E-03 0,01918346 ! regulation of bone resorption GO:0045124 11 10 0,000 8,117E-03 0,01917078 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 8,117E-03 0,0191581 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 8,117E-03 0,01914545 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 8,117E-03 0,01913281 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 8,117E-03 0,01912019 ! taste receptor activity GO:0008527 10 10 0,000 8,117E-03 0,01910759 ! Ran GTPase binding GO:0008536 10 10 0,000 8,117E-03 0,019095 ! endocytic vesicle membrane GO:0030666 10 10 0,000 8,117E-03 0,01908243 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 8,117E-03 0,01906988 ! ribosome assembly GO:0042255 10 10 0,000 8,117E-03 0,01905734 ! DNA methylation GO:0006306 12 10 0,000 8,117E-03 0,01904482 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 8,117E-03 0,01903231 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 8,117E-03 0,01901982 ! proteasome accessory complex GO:0022624 11 10 0,000 8,117E-03 0,01900735 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 8,117E-03 0,0189949 ! prostaglandin receptor activity GO:0004955 11 10 0,000 8,117E-03 0,01898246 ! regulation of isotype switching GO:0045191 14 10 0,000 8,117E-03 0,01897003 ! peptide transporter activity GO:0015197 10 10 0,000 8,117E-03 0,01895763 ! regulation of leukocyte migration GO:0002685 10 10 0,000 8,117E-03 0,01894524 ! retinoid-X receptor activity GO:0004886 10 10 0,000 8,117E-03 0,01893286 ! GTPase inhibitor activity GO:0005095 10 10 0,000 8,117E-03 0,0189205 ! pattern recognition receptor activity GO:0008329 10 10 0,000 8,117E-03 0,01890816 ! gamma-tubulin complex GO:0000930 12 10 0,000 8,117E-03 0,01889584 ! germ cell migration GO:0008354 10 10 0,000 8,117E-03 0,01888353 ! regulation of organic acid transport GO:0032890 10 10 0,000 8,117E-03 0,01887123 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 8,117E-03 0,01885895 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 8,117E-03 0,01884669 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 8,117E-03 0,01883445 ! sterol transporter activity GO:0015248 10 10 0,000 8,117E-03 0,01882222 ! regulation of embryonic development GO:0045995 11 10 0,000 8,117E-03 0,01881 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 8,925E-03 0,02066987 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 8,925E-03 0,02065647 ! negative regulation of blood pressure GO:0045776 11 11 0,000 8,925E-03 0,0206431 ! RNA cap binding GO:0000339 12 11 0,000 8,925E-03 0,02062973 ! CTP metabolic process GO:0046036 12 11 0,000 8,925E-03 0,02061639 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 8,925E-03 0,02060306 ! response to pain GO:0048265 11 11 0,000 8,925E-03 0,02058975 ! axonemal dynein complex GO:0005858 11 11 0,000 8,925E-03 0,02057646 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 8,925E-03 0,02056319 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 8,925E-03 0,02054993 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 8,925E-03 0,02053669 ! endocrine pancreas development GO:0031018 11 11 0,000 8,925E-03 0,02052346 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 8,925E-03 0,02051026 ! regulation of exit from mitosis GO:0007096 11 11 0,000 8,925E-03 0,02049707 ! chylomicron GO:0042627 11 11 0,000 8,925E-03 0,02048389 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 8,925E-03 0,02047074 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 8,925E-03 0,0204576 ! transforming growth factor beta binding GO:0050431 11 11 0,000 8,925E-03 0,02044448 ! glutamate metabolic process GO:0006536 12 11 0,000 8,925E-03 0,02043137 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 8,925E-03 0,02041828 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 8,925E-03 0,02040521 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 8,925E-03 0,02039216 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 8,925E-03 0,02037912 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 8,925E-03 0,0203661 ! epithelial cell development GO:0002064 11 11 0,000 8,925E-03 0,02035309 ! filamentous actin GO:0031941 11 11 0,000 8,925E-03 0,0203401 ! temperature homeostasis GO:0001659 11 11 0,000 8,925E-03 0,02032713 ! structural constituent of epidermis GO:0030280 13 11 0,000 8,925E-03 0,02031417 ! protein targeting to peroxisome GO:0006625 11 11 0,000 8,925E-03 0,02030124 ! spectrin GO:0008091 11 11 0,000 8,925E-03 0,02028831 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 8,925E-03 0,02027541 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 8,925E-03 0,02026252 ! regulation of phagocytosis GO:0050764 11 11 0,000 8,925E-03 0,02024964 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 8,925E-03 0,02023679 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 8,925E-03 0,02022395 ! regulation of B cell differentiation GO:0045577 15 11 0,000 8,925E-03 0,02021112 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 8,925E-03 0,02019831 ! basal lamina GO:0005605 12 11 0,000 8,925E-03 0,02018552 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 8,925E-03 0,02017275 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 8,925E-03 0,02015999 ! hindbrain morphogenesis GO:0021575 13 11 0,000 8,925E-03 0,02014724 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 8,925E-03 0,02013452 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 8,925E-03 0,02012181 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 8,925E-03 0,02010911 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 8,925E-03 0,02009643 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 8,925E-03 0,02008377 ! cofactor transporter activity GO:0051184 11 11 0,000 8,925E-03 0,02007112 ! cobalt ion binding GO:0050897 11 11 0,000 8,925E-03 0,02005849 ! pseudouridine synthase activity GO:0009982 12 11 0,000 8,925E-03 0,02004587 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 8,925E-03 0,02003327 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 8,925E-03 0,02002069 ! histone deacetylase binding GO:0042826 11 11 0,000 8,925E-03 0,02000812 ! spleen development GO:0048536 12 11 0,000 8,925E-03 0,01999557 ! regulation of RNA stability GO:0043487 11 11 0,000 8,925E-03 0,01998303 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 8,925E-03 0,01997051 ! acid-thiol ligase activity GO:0016878 11 11 0,000 8,925E-03 0,01995801 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 8,925E-03 0,01994552 ! blastocyst formation GO:0001825 11 11 0,000 8,925E-03 0,01993305 ! cerebellar cortex development GO:0021695 12 11 0,000 8,925E-03 0,01992059 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 8,925E-03 0,01990814 ! ADP binding GO:0043531 11 11 0,000 8,925E-03 0,01989572 ! folic acid binding GO:0005542 11 11 0,000 8,925E-03 0,01988331 ! FK506 binding GO:0005528 11 11 0,000 8,925E-03 0,01987091 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 8,925E-03 0,01985853 ! extracellular matrix binding GO:0050840 13 11 0,000 8,925E-03 0,01984616 ! microspike assembly GO:0030035 13 11 0,000 8,925E-03 0,01983381 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 8,925E-03 0,01982148 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 8,925E-03 0,01980916 ! organ formation GO:0048645 12 11 0,000 8,925E-03 0,01979686 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 8,925E-03 0,01978457 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 8,925E-03 0,0197723 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 8,925E-03 0,01976004 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 8,925E-03 0,01974779 ! Golgi vesicle budding GO:0048194 11 11 0,000 8,925E-03 0,01973557 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 8,925E-03 0,01972335 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 8,925E-03 0,01971116 ! ion channel inhibitor activity GO:0008200 13 11 0,000 8,925E-03 0,01969897 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 8,925E-03 0,01968681 ! MAP kinase kinase activity GO:0004708 11 11 0,000 8,925E-03 0,01967465 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 8,925E-03 0,01966252 ! mannosyltransferase activity GO:0000030 11 11 0,000 8,925E-03 0,01965039 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 8,925E-03 0,01963829 ! FMN binding GO:0010181 11 11 0,000 8,925E-03 0,01962619 ! response to X-ray GO:0010165 12 11 0,000 8,925E-03 0,01961412 ! focal adhesion formation GO:0048041 13 11 0,000 8,925E-03 0,01960205 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 8,925E-03 0,01959001 ! substrate-bound cell migration GO:0006929 11 11 0,000 8,925E-03 0,01957797 ! integrator complex GO:0032039 11 11 0,000 8,925E-03 0,01956595 ! UV protection GO:0009650 11 11 0,000 8,925E-03 0,01955395 ! L-glutamate transport GO:0015813 11 11 0,000 8,925E-03 0,01954196 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 8,925E-03 0,01952999 ! regulation of organ growth GO:0046620 12 11 0,000 8,925E-03 0,01951803 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 8,925E-03 0,01950608 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 8,925E-03 0,01949415 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 8,925E-03 0,01948224 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 8,925E-03 0,01947034 ! histone acetylation GO:0016573 11 11 0,000 8,925E-03 0,01945845 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 8,925E-03 0,01944658 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 8,925E-03 0,01943472 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 8,925E-03 0,01942288 ! chromatin silencing GO:0006342 11 11 0,000 8,925E-03 0,01941105 ! gland morphogenesis GO:0022612 12 11 0,000 8,925E-03 0,01939923 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 8,925E-03 0,01938743 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 8,925E-03 0,01937565 ! icosanoid receptor activity GO:0004953 12 11 0,000 8,925E-03 0,01936388 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 8,925E-03 0,01935212 ! negative regulation of neurological system process GO:0031645 12 11 0,000 8,925E-03 0,01934038 ! acid secretion GO:0046717 11 11 0,000 8,925E-03 0,01932865 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 8,925E-03 0,01931693 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 8,925E-03 0,01930523 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 8,925E-03 0,01929355 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 8,925E-03 0,01928188 ! midbody GO:0030496 11 11 0,000 8,925E-03 0,01927022 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 8,925E-03 0,01925857 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 8,925E-03 0,01924694 ! water channel activity GO:0015250 11 11 0,000 8,925E-03 0,01923533 ! response to nicotine GO:0035094 11 11 0,000 8,925E-03 0,01922373 ! response to cold GO:0009409 11 11 0,000 8,925E-03 0,01921214 ! adenylate cyclase activity GO:0004016 11 11 0,000 8,925E-03 0,01920057 ! 'de novo' protein folding GO:0006458 12 12 0,000 9,733E-03 0,02092565 ! centriole GO:0005814 12 12 0,000 9,733E-03 0,02091306 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 9,733E-03 0,02090049 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 9,733E-03 0,02088793 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 9,733E-03 0,02087538 ! bone remodeling GO:0046849 12 12 0,000 9,733E-03 0,02086285 ! peroxisomal transport GO:0043574 12 12 0,000 9,733E-03 0,02085034 ! retina development in camera-type eye GO:0060041 13 12 0,000 9,733E-03 0,02083784 ! hair follicle morphogenesis GO:0031069 12 12 0,000 9,733E-03 0,02082535 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 9,733E-03 0,02081288 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 9,733E-03 0,02080042 ! hippocampus development GO:0021766 12 12 0,000 9,733E-03 0,02078798 ! negative regulation of lipid metabolic process GO:0045833 13 12 0,000 9,733E-03 0,02077556 ! T cell selection GO:0045058 16 12 0,000 9,733E-03 0,02076315 ! cation:cation antiporter activity GO:0015491 12 12 0,000 9,733E-03 0,02075075 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 9,733E-03 0,02073837 ! T-tubule GO:0030315 13 12 0,000 9,733E-03 0,020726 ! methionine metabolic process GO:0006555 13 12 0,000 9,733E-03 0,02071365 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 9,733E-03 0,02070132 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 9,733E-03 0,02068899 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 9,733E-03 0,02067669 ! cell-cell junction assembly GO:0007043 12 12 0,000 9,733E-03 0,02066439 ! mitotic spindle organization GO:0007052 12 12 0,000 9,733E-03 0,02065212 ! fear response GO:0042596 12 12 0,000 9,733E-03 0,02063985 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 9,733E-03 0,0206276 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 9,733E-03 0,02061537 ! copper ion homeostasis GO:0055070 13 12 0,000 9,733E-03 0,02060315 ! lipoprotein receptor activity GO:0030228 12 12 0,000 9,733E-03 0,02059094 ! axon cargo transport GO:0008088 12 12 0,000 9,733E-03 0,02057875 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 9,733E-03 0,02056657 ! transcription elongation factor complex GO:0008023 13 12 0,000 9,733E-03 0,02055441 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 9,733E-03 0,02054226 ! nuclear outer membrane GO:0005640 12 12 0,000 9,733E-03 0,02053013 ! beta-tubulin binding GO:0048487 12 12 0,000 9,733E-03 0,02051801 ! autonomic nervous system development GO:0048483 12 12 0,000 9,733E-03 0,02050591 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 9,733E-03 0,02049381 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 9,733E-03 0,02048174 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 9,733E-03 0,02046968 ! regulation of epidermis development GO:0045682 12 12 0,000 9,733E-03 0,02045763 ! protein-chromophore linkage GO:0018298 12 12 0,000 9,733E-03 0,02044559 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 9,733E-03 0,02043357 ! cell killing GO:0001906 12 12 0,000 9,733E-03 0,02042157 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 9,733E-03 0,02040958 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 9,733E-03 0,0203976 ! detection of bacterium GO:0016045 13 12 0,000 9,733E-03 0,02038564 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 9,733E-03 0,02037369 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 9,733E-03 0,02036175 ! internal side of plasma membrane GO:0009898 14 12 0,000 9,733E-03 0,02034983 ! RNA 3'-end processing GO:0031123 12 12 0,000 9,733E-03 0,02033792 ! developmental induction GO:0031128 13 12 0,000 9,733E-03 0,02032603 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 9,733E-03 0,02031415 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 9,733E-03 0,02030228 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 9,733E-03 0,02029043 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 9,733E-03 0,02027859 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 9,733E-03 0,02026677 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 9,733E-03 0,02025496 ! thyroid gland development GO:0030878 12 12 0,000 9,733E-03 0,02024316 ! non-recombinational repair GO:0000726 12 12 0,000 9,733E-03 0,02023138 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 9,733E-03 0,02021961 ! lipid localization GO:0010876 12 12 0,000 9,733E-03 0,02020785 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 9,733E-03 0,02019611 ! response to cAMP GO:0051591 12 12 0,000 9,733E-03 0,02018438 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 9,733E-03 0,02017267 ! T cell proliferation GO:0042098 17 12 0,000 9,733E-03 0,02016097 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 9,733E-03 0,02014928 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 9,733E-03 0,02013761 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 9,733E-03 0,02012595 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 9,733E-03 0,0201143 ! drug transport GO:0015893 12 12 0,000 9,733E-03 0,02010267 ! GTP-dependent protein binding GO:0030742 12 12 0,000 9,733E-03 0,02009105 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 9,733E-03 0,02007944 ! T cell receptor complex GO:0042101 12 12 0,000 9,733E-03 0,02006785 ! membrane protein proteolysis GO:0033619 13 12 0,000 9,733E-03 0,02005627 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 9,733E-03 0,0200447 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 9,733E-03 0,02003315 ! histone acetyltransferase complex GO:0000123 13 12 0,000 9,733E-03 0,02002161 ! dendritic spine GO:0043197 12 12 0,000 9,733E-03 0,02001008 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 9,733E-03 0,01999857 ! alpha-beta T cell activation GO:0046631 13 12 0,000 9,733E-03 0,01998707 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 9,733E-03 0,01997558 ! vasoconstriction GO:0042310 13 12 0,000 9,733E-03 0,01996411 ! DNA unwinding during replication GO:0006268 12 12 0,000 9,733E-03 0,01995265 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 9,733E-03 0,0199412 ! mRNA splice site selection GO:0006376 13 12 0,000 9,733E-03 0,01992976 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 9,733E-03 0,01991834 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 9,733E-03 0,01990694 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 9,733E-03 0,01989554 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 9,733E-03 0,01988416 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 9,733E-03 0,01987279 ! hexosaminidase activity GO:0015929 12 12 0,000 9,733E-03 0,01986143 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 9,733E-03 0,01985009 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 9,733E-03 0,01983876 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 9,733E-03 0,01982744 ! protein kinase C binding GO:0005080 13 12 0,000 9,733E-03 0,01981614 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 9,733E-03 0,01980485 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 9,733E-03 0,01979357 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 0,000 9,733E-03 0,0197823 ! L-fucose metabolic process GO:0042354 14 12 0,000 9,733E-03 0,01977105 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 9,733E-03 0,01975981 ! C-acyltransferase activity GO:0016408 12 12 0,000 9,733E-03 0,01974859 ! steroid hydroxylase activity GO:0008395 12 12 0,000 9,733E-03 0,01973737 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 9,733E-03 0,01972617 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 9,733E-03 0,01971498 ! SWI/SNF-type complex GO:0070603 13 12 0,000 9,733E-03 0,0197038 GO:0016514|SWI/SNF complex, ! cilium part GO:0044441 12 12 0,000 9,733E-03 0,01969264 ! positive regulation of translation GO:0045727 13 13 0,000 0,01054044 0,02131366 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01054044 0,0213016 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01054044 0,02128955 ! superoxide anion generation GO:0042554 13 13 0,000 0,01054044 0,02127752 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01054044 0,02126549 ! cis-Golgi network GO:0005801 14 13 0,000 0,01054044 0,02125349 ! regulation of S phase GO:0033261 17 13 0,000 0,01054044 0,02124149 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01054044 0,02122951 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01054044 0,02121754 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 0,01054044 0,02120559 ! endothelial cell migration GO:0043542 13 13 0,000 0,01054044 0,02119365 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01054044 0,02118172 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01054044 0,02116981 ! cartilage condensation GO:0001502 14 13 0,000 0,01054044 0,02115791 ! organelle fusion GO:0048284 14 13 0,000 0,01054044 0,02114602 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01054044 0,02113415 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01054044 0,02112229 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01054044 0,02111045 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01054044 0,02109861 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01054044 0,02108679 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01054044 0,02107499 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01054044 0,02106319 ! arginine metabolic process GO:0006525 13 13 0,000 0,01054044 0,02105141 ! WW domain binding GO:0050699 14 13 0,000 0,01054044 0,02103964 ! cholesterol binding GO:0015485 13 13 0,000 0,01054044 0,02102789 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01054044 0,02101615 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01054044 0,02100442 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01054044 0,02099271 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01054044 0,02098101 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01054044 0,02096932 ! regulation of heart rate GO:0002027 14 13 0,000 0,01054044 0,02095764 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01054044 0,02094598 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01054044 0,02093433 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01054044 0,02092269 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01054044 0,02091107 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01054044 0,02089946 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01054044 0,02088786 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01054044 0,02087628 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01054044 0,0208647 ! NADP metabolic process GO:0006739 13 13 0,000 0,01054044 0,02085314 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01054044 0,0208416 ! intestinal absorption GO:0050892 13 13 0,000 0,01054044 0,02083006 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01054044 0,02081854 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01054044 0,02080703 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01054044 0,02079554 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01054044 0,02078406 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01054044 0,02077259 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01054044 0,02076113 ! embryonic placenta development GO:0001892 13 13 0,000 0,01054044 0,02074968 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01054044 0,02073825 ! insulin secretion GO:0030073 13 13 0,000 0,01054044 0,02072683 ! regulation of protein ubiquitination GO:0031396 13 13 0,000 0,01054044 0,02071542 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01054044 0,02070403 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01054044 0,02069265 ! replisome GO:0030894 14 13 0,000 0,01054044 0,02068128 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01054044 0,02066992 ! double-strand break repair via homologous recombination GO:0000724 13 13 0,000 0,01054044 0,02065858 GO:0000725|recombinational repair, ! copper ion transport GO:0006825 13 13 0,000 0,01054044 0,02064724 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01054044 0,02063592 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01054044 0,02062462 ! mating GO:0007618 13 13 0,000 0,01054044 0,02061332 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01054044 0,02060204 ! MAP kinase activity GO:0004707 14 13 0,000 0,01054044 0,02059077 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01054044 0,02057951 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01054044 0,02056826 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01054044 0,02055703 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01054044 0,02054581 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01054044 0,0205346 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01054044 0,0205234 ! protein kinase C activity GO:0004697 15 13 0,000 0,01054044 0,02051222 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01054044 0,02050105 ! water transporter activity GO:0005372 13 13 0,000 0,01054044 0,02048989 ! exocrine system development GO:0035272 14 13 0,000 0,01054044 0,02047874 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01054044 0,0204676 ! monoamine transport GO:0015844 13 13 0,000 0,01054044 0,02045648 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01054044 0,02044537 ! embryo implantation GO:0007566 13 13 0,000 0,01054044 0,02043427 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01054044 0,02042318 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01054044 0,02041211 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01054044 0,02040104 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01054044 0,02038999 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01054044 0,02037895 ! MHC class I protein binding GO:0042288 13 13 0,000 0,01054044 0,02036792 ! histone deacetylation GO:0016575 13 13 0,000 0,01054044 0,02035691 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01054044 0,02034591 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01054044 0,02033491 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01054044 0,02032393 ! response to gamma radiation GO:0010332 13 13 0,000 0,01054044 0,02031297 ! sarcomere organization GO:0045214 13 13 0,000 0,01054044 0,02030201 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01054044 0,02029106 ! cAMP binding GO:0030552 13 13 0,000 0,01054044 0,02028013 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01054044 0,02026921 ! cilium assembly GO:0042384 13 13 0,000 0,01054044 0,0202583 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01054044 0,0202474 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01054044 0,02023652 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01054044 0,02022564 ! acrosome reaction GO:0007340 13 13 0,000 0,01054044 0,02021478 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01054044 0,02020393 ! nucleolar part GO:0044452 13 13 0,000 0,01054044 0,02019309 ! axoneme part GO:0044447 13 13 0,000 0,01054044 0,02018227 ! tRNA modification GO:0006400 14 14 0,000 0,01134701 0,021715 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01134701 0,02170337 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01134701 0,02169175 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01134701 0,02168014 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01134701 0,02166855 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01134701 0,02165697 ! guanylate kinase activity GO:0004385 16 14 0,000 0,01134701 0,0216454 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01134701 0,02163384 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01134701 0,0216223 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01134701 0,02161077 ! palate development GO:0060021 15 14 0,000 0,01134701 0,02159925 ! centrosome cycle GO:0007098 14 14 0,000 0,01134701 0,02158774 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01134701 0,02157624 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01134701 0,02156476 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01134701 0,02155329 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01134701 0,02154183 ! glycine metabolic process GO:0006544 15 14 0,000 0,01134701 0,02153039 ! plasma membrane organization GO:0007009 14 14 0,000 0,01134701 0,02151895 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01134701 0,02150753 ! response to retinoic acid GO:0032526 14 14 0,000 0,01134701 0,02149612 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01134701 0,02148472 ! lysosomal transport GO:0007041 14 14 0,000 0,01134701 0,02147334 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01134701 0,02146196 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01134701 0,0214506 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01134701 0,02143925 ! bone mineralization GO:0030282 14 14 0,000 0,01134701 0,02142791 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01134701 0,02141659 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01134701 0,02140527 ! cerebellum development GO:0021549 15 14 0,000 0,01134701 0,02139397 ! G1 phase GO:0051318 14 14 0,000 0,01134701 0,02138268 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01134701 0,02137141 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01134701 0,02136014 ! water homeostasis GO:0030104 14 14 0,000 0,01134701 0,02134889 ! peptide hormone binding GO:0017046 14 14 0,000 0,01134701 0,02133764 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01134701 0,02132641 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01134701 0,02131519 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01134701 0,02130399 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01134701 0,02129279 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01134701 0,02128161 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01134701 0,02127044 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01134701 0,02125928 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01134701 0,02124813 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01134701 0,02123699 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01134701 0,02122587 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01134701 0,02121476 ! lactation GO:0007595 15 14 0,000 0,01134701 0,02120366 ! reproductive cellular process GO:0048610 14 14 0,000 0,01134701 0,02119257 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01134701 0,02118149 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01134701 0,02117042 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01134701 0,02115937 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01134701 0,02114832 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01134701 0,02113729 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01134701 0,02112627 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01134701 0,02111526 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01134701 0,02110426 ! startle response GO:0001964 14 14 0,000 0,01134701 0,02109328 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01134701 0,0210823 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01134701 0,02107134 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01134701 0,02106039 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01134701 0,02104945 ! organic alcohol transport GO:0015850 15 14 0,000 0,01134701 0,02103852 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01134701 0,0210276 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01134701 0,02101669 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01134701 0,0210058 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01134701 0,02099491 ! L-amino acid transport GO:0015807 14 14 0,000 0,01134701 0,02098404 ! microfilament motor activity GO:0000146 14 14 0,000 0,01134701 0,02097318 ! stem cell development GO:0048864 14 14 0,000 0,01134701 0,02096233 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01134701 0,02095149 ! DNA replication initiation GO:0006270 14 14 0,000 0,01134701 0,02094066 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01134701 0,02092985 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01134701 0,02091904 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01134701 0,02090825 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01134701 0,02089747 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01134701 0,02088669 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01134701 0,02087593 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01134701 0,02086518 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01134701 0,02085444 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01134701 0,02084372 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01134701 0,020833 ! ion gated channel activity GO:0022839 16 14 0,000 0,01134701 0,02082229 ! male genitalia development GO:0030539 14 14 0,000 0,01134701 0,0208116 ! regulation of axon extension GO:0030516 15 14 0,000 0,01134701 0,02080092 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01134701 0,02079024 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01134701 0,02077958 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01134701 0,02076893 ! defense response to virus GO:0051607 19 14 0,000 0,01134701 0,02075829 ! cadherin binding GO:0045296 16 14 0,000 0,01134701 0,02074766 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01215298 0,02220998 ! nuclear replication fork GO:0043596 16 15 0,000 0,01215298 0,02219862 ! skin development GO:0043588 16 15 0,000 0,01215298 0,02218727 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01215298 0,02217593 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01215298 0,0221646 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01215298 0,02215329 ! polysome GO:0005844 16 15 0,000 0,01215298 0,02214199 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01215298 0,0221307 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01215298 0,02211942 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01215298 0,02210815 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01215298 0,02209689 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01215298 0,02208565 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01215298 0,02207441 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01215298 0,02206319 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01215298 0,02205198 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01215298 0,02204078 ! response to vitamin A GO:0033189 15 15 0,000 0,01215298 0,02202959 ! protease binding GO:0002020 16 15 0,000 0,01215298 0,02201841 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01215298 0,02200725 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01215298 0,02199609 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01215298 0,02198495 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01215298 0,02197382 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01215298 0,0219627 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01215298 0,02195159 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01215298 0,02194049 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01215298 0,02192941 ! filopodium GO:0030175 15 15 0,000 0,01215298 0,02191833 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01215298 0,02190727 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01215298 0,02189621 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01215298 0,02188517 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01215298 0,02187414 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01215298 0,02186312 ! SMAD binding GO:0046332 16 15 0,000 0,01215298 0,02185211 ! nerve development GO:0021675 16 15 0,000 0,01215298 0,02184111 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01215298 0,02183013 ! mannose binding GO:0005537 15 15 0,000 0,01215298 0,02181915 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01215298 0,02180819 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01215298 0,02179723 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01215298 0,02178629 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01215298 0,02177536 ! synaptonemal complex GO:0000795 15 15 0,000 0,01215298 0,02176444 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01215298 0,02175353 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01215298 0,02174263 ! water transport GO:0006833 15 15 0,000 0,01215298 0,02173174 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01215298 0,02172087 ! viral genome replication GO:0019079 15 15 0,000 0,01215298 0,02171 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01215298 0,02169915 ! inositol metabolic process GO:0006020 15 15 0,000 0,01215298 0,0216883 ! sulfate transport GO:0008272 15 15 0,000 0,01215298 0,02167747 ! protein-lipid complex GO:0032994 15 15 0,000 0,01215298 0,02166665 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01215298 0,02165584 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01215298 0,02164503 ! heart looping GO:0001947 15 15 0,000 0,01215298 0,02163424 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01215298 0,02162346 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01215298 0,0216127 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01215298 0,02160194 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01215298 0,02159119 ! response to osmotic stress GO:0006970 16 15 0,000 0,01215298 0,02158045 ! fructose metabolic process GO:0006000 15 15 0,000 0,01215298 0,02156973 ! ubiquitin binding GO:0043130 15 15 0,000 0,01215298 0,02155901 ! vesicle coating GO:0006901 16 15 0,000 0,01215298 0,02154831 ! DNA integration GO:0015074 16 15 0,000 0,01215298 0,02153761 ! alcohol binding GO:0043178 16 15 0,000 0,01215298 0,02152693 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01215298 0,02151626 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01215298 0,0215056 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01215298 0,02149494 ! genitalia development GO:0048806 15 15 0,000 0,01215298 0,0214843 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01215298 0,02147367 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01215298 0,02146305 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01215298 0,02145244 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01215298 0,02144184 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01215298 0,02143126 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01215298 0,02142068 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01215298 0,02141011 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01215298 0,02139955 ! receptor activator activity GO:0030546 15 15 0,000 0,01215298 0,02138901 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01215298 0,02137847 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01215298 0,02136794 ! histone binding GO:0042393 15 15 0,000 0,01215298 0,02135743 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01215298 0,02134692 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01215298 0,02133643 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01215298 0,02132594 ! drug transporter activity GO:0015238 15 15 0,000 0,01215298 0,02131547 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01215298 0,021305 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01215298 0,02129455 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01215298 0,02128411 ! peptide hormone processing GO:0016486 17 15 0,000 0,01215298 0,02127367 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01215298 0,02126325 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01215298 0,02125284 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01295835 0,02265015 ! positive regulation of cell size GO:0045793 16 16 0,000 0,01295835 0,02263907 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01295835 0,022628 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01295835 0,02261694 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01295835 0,02260589 ! response to vitamin GO:0033273 16 16 0,000 0,01295835 0,02259485 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01295835 0,02258382 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01295835 0,02257281 ! kinesin complex GO:0005871 16 16 0,000 0,01295835 0,0225618 ! cornified envelope GO:0001533 18 16 0,000 0,01295835 0,0225508 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01295835 0,02253982 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01295835 0,02252885 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01295835 0,02251788 ! pituitary gland development GO:0021983 16 16 0,000 0,01295835 0,02250693 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01295835 0,02249599 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01295835 0,02248506 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01295835 0,02247414 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01295835 0,02246323 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01295835 0,02245233 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01295835 0,02244144 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01295835 0,02243056 ! beta-catenin binding GO:0008013 17 16 0,000 0,01295835 0,0224197 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01295835 0,02240884 ! neuron recognition GO:0008038 17 16 0,000 0,01295835 0,02239799 ! oogenesis GO:0048477 19 16 0,000 0,01295835 0,02238716 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01295835 0,02237633 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01295835 0,02236552 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01295835 0,02235471 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01295835 0,02234392 ! biomineral formation GO:0031214 16 16 0,000 0,01295835 0,02233313 ! vitamin transport GO:0051180 16 16 0,000 0,01295835 0,02232236 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01295835 0,0223116 ! organic cation transport GO:0015695 16 16 0,000 0,01295835 0,02230084 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01295835 0,0222901 ! regulation of glucose import GO:0046324 17 16 0,000 0,01295835 0,02227937 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01295835 0,02226865 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01295835 0,02225794 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01295835 0,02224724 ! tRNA binding GO:0000049 16 16 0,000 0,01295835 0,02223655 ! regulation of cell killing GO:0031341 20 16 0,000 0,01295835 0,02222587 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01295835 0,0222152 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01295835 0,02220454 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01295835 0,02219389 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01295835 0,02218325 ! axis specification GO:0009798 16 16 0,000 0,01295835 0,02217262 ! adult walking behavior GO:0007628 17 16 0,000 0,01295835 0,022162 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01295835 0,02215139 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01295835 0,02214079 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01295835 0,0221302 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01295835 0,02211962 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01295835 0,02210905 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01295835 0,0220985 ! SH2 domain binding GO:0042169 19 16 0,000 0,01295835 0,02208795 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01295835 0,02207741 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01295835 0,02206688 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01295835 0,02205636 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01295835 0,02204586 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01295835 0,02203536 ! cellular pigmentation GO:0033059 16 16 0,000 0,01295835 0,02202487 ! mannosidase activity GO:0015923 19 16 0,000 0,01295835 0,02201439 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01295835 0,02200392 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01295835 0,02199347 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01295835 0,02198302 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01295835 0,02197258 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01295835 0,02196215 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01295835 0,02195173 ! axoneme GO:0005930 16 16 0,000 0,01295835 0,02194132 ! anion exchanger activity GO:0015380 18 17 0,000 0,01376311 0,02329292 ! neuron maturation GO:0042551 18 17 0,000 0,01376311 0,02328189 ! metencephalon development GO:0022037 18 17 0,000 0,01376311 0,02327086 ! regulation of lipid biosynthetic process GO:0046890 18 17 0,000 0,01376311 0,02325985 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01376311 0,02324885 ! hemoglobin complex GO:0005833 18 17 0,000 0,01376311 0,02323785 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01376311 0,02322687 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01376311 0,0232159 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01376311 0,02320494 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01376311 0,02319399 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01376311 0,02318305 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01376311 0,02317212 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01376311 0,0231612 GO:0032982|myosin filament, ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 0,000 0,01376311 0,02315029 ! glial cell development GO:0021782 17 17 0,000 0,01376311 0,02313939 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01376311 0,0231285 ! pancreas development GO:0031016 17 17 0,000 0,01376311 0,02311762 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01376311 0,02310675 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01376311 0,02309589 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01376311 0,02308504 ! cerebral cortex development GO:0021987 17 17 0,000 0,01376311 0,02307421 ! cellular response to starvation GO:0009267 18 17 0,000 0,01376311 0,02306338 ! signal sequence binding GO:0005048 17 17 0,000 0,01376311 0,02305256 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01376311 0,02304175 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01376311 0,02303096 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01376311 0,02302017 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01376311 0,02300939 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01376311 0,02299862 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01376311 0,02298787 ! actin filament bundle GO:0032432 17 17 0,000 0,01376311 0,02297712 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01376311 0,02296638 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01376311 0,02295566 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01376311 0,02294494 ! regulation of protein binding GO:0043393 18 17 0,000 0,01376311 0,02293423 ! recycling endosome GO:0055037 18 17 0,000 0,01376311 0,02292354 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01376311 0,02291285 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01376311 0,02290217 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01376311 0,0228915 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01376311 0,02288085 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01376311 0,0228702 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01376311 0,02285956 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01376311 0,02284894 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01376311 0,02283832 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01376311 0,02282771 ! steroid catabolic process GO:0006706 17 17 0,000 0,01376311 0,02281711 ! oxygen transport GO:0015671 18 17 0,000 0,01376311 0,02280652 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01376311 0,02279595 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01376311 0,02278538 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01376311 0,02277482 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01376311 0,02276427 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01376311 0,02275373 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01376311 0,0227432 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01376311 0,02273268 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01376311 0,02272217 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01376311 0,02271167 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01376311 0,02270118 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01376311 0,0226907 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01376311 0,02268023 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01376311 0,02266977 ! fucose metabolic process GO:0006004 19 17 0,000 0,01376311 0,02265932 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01376311 0,02264888 ! membrane budding GO:0006900 18 17 0,000 0,01376311 0,02263844 ! AMP binding GO:0016208 17 17 0,000 0,01376311 0,02262802 ! nuclear ubiquitin ligase complex GO:0000152 17 17 0,000 0,01376311 0,02261761 ! body fluid secretion GO:0007589 18 17 0,000 0,01376311 0,0226072 ! response to fungus GO:0009620 17 17 0,000 0,01376311 0,02259681 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01376311 0,02258642 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01376311 0,02257605 ! rRNA binding GO:0019843 17 17 0,000 0,01376311 0,02256568 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01376311 0,02255533 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01376311 0,02254498 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01376311 0,02253464 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01376311 0,02252432 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01376311 0,022514 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01376311 0,02250369 ! tissue regeneration GO:0042246 17 17 0,000 0,01376311 0,02249339 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01376311 0,0224831 ! muscle maintenance GO:0046716 18 17 0,000 0,01376311 0,02247282 ! cell-cell junction organization GO:0045216 17 17 0,000 0,01376311 0,02246255 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01376311 0,02245229 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01376311 0,02244204 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01376311 0,02243179 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01376311 0,02242156 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01376311 0,02241134 ! chaperone binding GO:0051087 18 18 0,000 0,01456727 0,02370999 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01456727 0,02369919 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01456727 0,0236884 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01456727 0,02367761 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01456727 0,02366684 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01456727 0,02365608 ! limbic system development GO:0021761 18 18 0,000 0,01456727 0,02364533 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01456727 0,02363458 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01456727 0,02362385 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01456727 0,02361313 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01456727 0,02360241 ! lysosome organization GO:0007040 18 18 0,000 0,01456727 0,02359171 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01456727 0,02358102 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01456727 0,02357033 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01456727 0,02355966 ! peptide cross-linking GO:0018149 20 18 0,000 0,01456727 0,02354899 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01456727 0,02353833 ! presynaptic membrane GO:0042734 19 18 0,000 0,01456727 0,02352769 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01456727 0,02351705 ! neural crest cell migration GO:0001755 18 18 0,000 0,01456727 0,02350643 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01456727 0,02349581 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01456727 0,0234852 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01456727 0,0234746 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01456727 0,02346401 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01456727 0,02345344 ! cell-cell recognition GO:0009988 19 18 0,000 0,01456727 0,02344287 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01456727 0,02343231 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01456727 0,02342176 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01456727 0,02341122 ! actin filament-based movement GO:0030048 18 18 0,000 0,01456727 0,02340068 ! negative regulation of translation GO:0017148 20 18 0,000 0,01456727 0,02339016 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01456727 0,02337965 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01456727 0,02336915 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01456727 0,02335865 ! negative regulation of cell cycle process GO:0010948 18 18 0,000 0,01456727 0,02334817 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01456727 0,02333769 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01456727 0,02332723 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01456727 0,02331677 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01456727 0,02330633 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01456727 0,02329589 ! small conjugating protein binding GO:0032182 18 18 0,000 0,01456727 0,02328546 ! memory GO:0007613 19 18 0,000 0,01456727 0,02327504 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01456727 0,02326463 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01456727 0,02325423 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01456727 0,02324384 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01456727 0,02323346 ! pigmentation during development GO:0048066 21 18 0,000 0,01456727 0,02322309 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01456727 0,02321273 ! acetylcholine binding GO:0042166 19 18 0,000 0,01456727 0,02320237 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01456727 0,02319203 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01456727 0,02318169 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01456727 0,02317137 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01456727 0,02316105 ! coreceptor activity GO:0015026 18 18 0,000 0,01456727 0,02315074 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01456727 0,02314044 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01456727 0,02313016 ! cytolysis GO:0019835 18 18 0,000 0,01456727 0,02311988 ! phosphate binding GO:0042301 19 18 0,000 0,01456727 0,0231096 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01456727 0,02309934 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01456727 0,02308909 ! DNA modification GO:0006304 20 18 0,000 0,01456727 0,02307885 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01456727 0,02306861 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01456727 0,02305839 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01456727 0,02304817 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01456727 0,02303796 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01456727 0,02302776 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01456727 0,02301758 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01456727 0,02300739 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01456727 0,02299722 ! connexon complex GO:0005922 18 18 0,000 0,01456727 0,02298706 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01456727 0,02297691 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01537083 0,02423366 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01537083 0,02422296 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01537083 0,02421228 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01537083 0,0242016 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01537083 0,02419094 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01537083 0,02418028 ! spindle microtubule GO:0005876 20 19 0,000 0,01537083 0,02416963 ! ovarian follicle development GO:0001541 19 19 0,000 0,01537083 0,02415899 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01537083 0,02414836 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01537083 0,02413775 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01537083 0,02412714 ! vacuolar transport GO:0007034 19 19 0,000 0,01537083 0,02411653 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01537083 0,02410594 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01537083 0,02409536 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01537083 0,02408479 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01537083 0,02407423 ! cell projection membrane GO:0031253 20 19 0,000 0,01537083 0,02406367 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01537083 0,02405313 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01537083 0,02404259 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01537083 0,02403206 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01537083 0,02402155 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01537083 0,02401104 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01537083 0,02400054 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01537083 0,02399005 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01537083 0,02397957 ! retinoid binding GO:0005501 19 19 0,000 0,01537083 0,0239691 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01537083 0,02395864 ! protein stabilization GO:0050821 20 19 0,000 0,01537083 0,02394818 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01537083 0,02393774 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01537083 0,0239273 ! microtubule-based transport GO:0010970 19 19 0,000 0,01537083 0,02391688 ! protein complex scaffold GO:0032947 19 19 0,000 0,01537083 0,02390646 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01537083 0,02389605 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01537083 0,02388565 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01537083 0,02387526 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01537083 0,02386488 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01537083 0,02385451 ! glycoprotein binding GO:0001948 23 19 0,000 0,01537083 0,02384415 ! sensory perception of taste GO:0050909 19 19 0,000 0,01537083 0,0238338 ! myoblast differentiation GO:0045445 19 19 0,000 0,01537083 0,02382345 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01537083 0,02381312 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01537083 0,02380279 ! myosin binding GO:0017022 19 19 0,000 0,01537083 0,02379247 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01537083 0,02378216 ! cell aging GO:0007569 19 19 0,000 0,01537083 0,02377186 ! stem cell differentiation GO:0048863 19 19 0,000 0,01537083 0,02376157 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01537083 0,02375129 ! heart process GO:0003015 20 19 0,000 0,01537083 0,02374102 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01537083 0,02373075 ! secretory granule membrane GO:0030667 20 19 0,000 0,01537083 0,0237205 ! MHC protein binding GO:0042287 19 19 0,000 0,01537083 0,02371025 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01537083 0,02370001 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01537083 0,02368979 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01537083 0,02367957 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01537083 0,02366935 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01537083 0,02365915 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01537083 0,02364896 ! insulin receptor binding GO:0005158 20 19 0,000 0,01537083 0,02363877 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01537083 0,0236286 ! protein secretion GO:0009306 20 20 0,000 0,01617379 0,02485224 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,01617379 0,02484155 ! proteasome core complex GO:0005839 20 20 0,000 0,01617379 0,02483087 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,01617379 0,0248202 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,01617379 0,02480954 ! glutathione transferase activity GO:0004364 20 20 0,000 0,01617379 0,02479888 ! microtubule organizing center organization GO:0031023 20 20 0,000 0,01617379 0,02478824 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,01617379 0,02477761 ! actomyosin GO:0042641 20 20 0,000 0,01617379 0,02476698 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,01617379 0,02475637 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,01617379 0,02474576 ! vacuole organization GO:0007033 20 20 0,000 0,01617379 0,02473516 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,01617379 0,02472457 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,01617379 0,02471399 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,01617379 0,02470342 ! regulation of exocytosis GO:0017157 21 20 0,000 0,01617379 0,02469286 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,01617379 0,02468231 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,01617379 0,02467177 ! kinase activator activity GO:0019209 20 20 0,000 0,01617379 0,02466123 ! diencephalon development GO:0021536 20 20 0,000 0,01617379 0,02465071 ! nuclear inner membrane GO:0005637 20 20 0,000 0,01617379 0,02464019 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,01617379 0,02462968 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,01617379 0,02461918 ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 0,000 0,01617379 0,02460869 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,01617379 0,02459821 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,01617379 0,02458774 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,01617379 0,02457728 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,01617379 0,02456682 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,01617379 0,02455638 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,01617379 0,02454594 ! alditol metabolic process GO:0019400 21 20 0,000 0,01617379 0,02453551 ! liver development GO:0001889 20 20 0,000 0,01617379 0,0245251 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,01617379 0,02451469 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,01617379 0,02450429 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,01617379 0,02449389 ! response to alkaloid GO:0043279 22 20 0,000 0,01617379 0,02448351 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,01617379 0,02447314 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,01617379 0,02446277 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,01617379 0,02445241 ! heme metabolic process GO:0042168 22 20 0,000 0,01617379 0,02444207 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,01617379 0,02443173 ! sex determination GO:0007530 20 20 0,000 0,01617379 0,0244214 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,01617379 0,02441107 ! peptide secretion GO:0002790 21 20 0,000 0,01617379 0,02440076 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,01617379 0,02439046 ! interaction with host GO:0051701 24 20 0,000 0,01617379 0,02438016 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,01617379 0,02436987 ! vasodilation GO:0042311 21 20 0,000 0,01617379 0,0243596 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,01617379 0,02434933 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,01617379 0,02433907 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,01617379 0,02432881 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,01617379 0,02431857 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,01617379 0,02430833 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,01617379 0,02429811 ! microvillus GO:0005902 20 20 0,000 0,01617379 0,02428789 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,01617379 0,02427768 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,01617379 0,02426748 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,01697615 0,02546066 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,01697615 0,02544997 ! growth cone GO:0030426 22 21 0,000 0,01697615 0,02543929 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,01697615 0,02542862 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,01697615 0,02541796 ! hormone secretion GO:0046879 22 21 0,000 0,01697615 0,0254073 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,01697615 0,02539666 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,01697615 0,02538602 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,01697615 0,0253754 GO:0034704|calcium channel complex, ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,01697615 0,02536478 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,01697615 0,02535417 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 0,000 0,01697615 0,02534357 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,01697615 0,02533298 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,01697615 0,0253224 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,01697615 0,02531183 ! Golgi stack GO:0005795 25 21 0,000 0,01697615 0,02530126 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,01697615 0,02529071 ! muscle cell development GO:0055001 21 21 0,000 0,01697615 0,02528016 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,01697615 0,02526962 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,01697615 0,02525909 ! deacetylase activity GO:0019213 22 21 0,000 0,01697615 0,02524857 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,01697615 0,02523806 ! regulation of fatty acid metabolic process GO:0019217 22 21 0,000 0,01697615 0,02522756 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,01697615 0,02521707 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,01697615 0,02520658 ! pentose metabolic process GO:0019321 22 21 0,000 0,01697615 0,0251961 ! collagen fibril organization GO:0030199 22 21 0,000 0,01697615 0,02518564 ! platelet activation GO:0030168 23 21 0,000 0,01697615 0,02517518 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,01697615 0,02516473 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,01697615 0,02515429 ! glutathione metabolic process GO:0006749 21 21 0,000 0,01697615 0,02514385 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,01697615 0,02513343 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,01697615 0,02512301 ! cyclase activity GO:0009975 21 21 0,000 0,01697615 0,0251126 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,01697615 0,02510221 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,01697615 0,02509182 ! fatty acid binding GO:0005504 21 21 0,000 0,01697615 0,02508143 ! gut development GO:0048565 21 21 0,000 0,01697615 0,02507106 ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,01697615 0,0250607 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,01697615 0,02505034 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,01697615 0,02503999 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,01697615 0,02502966 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,01697615 0,02501933 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,01697615 0,025009 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,01697615 0,02499869 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,01697615 0,02498839 ! sterol binding GO:0032934 21 21 0,000 0,01697615 0,02497809 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,01697615 0,0249678 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,01697615 0,02495752 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,01697615 0,02494725 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,01697615 0,02493699 ! phosphatase binding GO:0019902 22 21 0,000 0,01697615 0,02492674 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,01697615 0,02491649 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,01697615 0,02490626 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,01697615 0,02489603 ! vesicle targeting GO:0006903 22 21 0,000 0,01697615 0,02488581 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,01697615 0,0248756 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,01697615 0,02486539 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,01697615 0,0248552 ! renal system process GO:0003014 22 21 0,000 0,01697615 0,02484501 ! base-excision repair GO:0006284 21 21 0,000 0,01697615 0,02483483 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,01697615 0,02482466 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,01697615 0,0248145 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,01697615 0,02480435 ! fatty acid transport GO:0015908 21 21 0,000 0,01697615 0,0247942 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,01697615 0,02478407 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,01697615 0,02477394 ! collagen catabolic process GO:0030574 21 21 0,000 0,01697615 0,02476382 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,01697615 0,02475371 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,01697615 0,0247436 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,01697615 0,02473351 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,01777791 0,02589107 ! site of polarized growth GO:0030427 23 22 0,000 0,01777791 0,02588052 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,01777791 0,02586997 ! leukocyte adhesion GO:0007159 27 22 0,000 0,01777791 0,02585943 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,01777791 0,0258489 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,01777791 0,02583838 ! peroxisome organization GO:0007031 22 22 0,000 0,01777791 0,02582787 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,01777791 0,02581737 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,01777791 0,02580687 ! response to starvation GO:0042594 23 22 0,000 0,01777791 0,02579639 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,01777791 0,02578591 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,01777791 0,02577544 ! membrane depolarization GO:0051899 24 22 0,000 0,01777791 0,02576498 ! somitogenesis GO:0001756 23 22 0,000 0,01777791 0,02575453 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,01777791 0,02574408 ! natural killer cell activation GO:0030101 22 22 0,000 0,01777791 0,02573365 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,01777791 0,02572322 ! basal plasma membrane GO:0009925 22 22 0,000 0,01777791 0,0257128 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,01777791 0,02570239 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,01777791 0,02569199 ! telomere organization GO:0032200 23 22 0,000 0,01777791 0,0256816 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,01777791 0,02567121 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,01777791 0,02566084 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,01777791 0,02565047 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,01777791 0,02564011 ! initiation of viral infection GO:0019059 22 22 0,000 0,01777791 0,02562976 ! RNA polymerase complex GO:0030880 23 22 0,000 0,01777791 0,02561941 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,01777791 0,02560908 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,01777791 0,02559875 ! response to ethanol GO:0045471 25 22 0,000 0,01777791 0,02558844 ! syntaxin binding GO:0019905 23 22 0,000 0,01777791 0,02557813 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,01777791 0,02556783 ! digestive system process GO:0022600 24 22 0,000 0,01777791 0,02555753 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,01777791 0,02554725 ! autophagy GO:0006914 24 22 0,000 0,01777791 0,02553697 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,01777791 0,0255267 ! transaminase activity GO:0008483 23 22 0,000 0,01777791 0,02551644 ! sarcoplasm GO:0016528 23 22 0,000 0,01777791 0,02550619 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,01777791 0,02549595 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,01777791 0,02548571 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,01777791 0,02547549 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,01777791 0,02546527 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,01777791 0,02545506 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,01777791 0,02544485 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,01777791 0,02543466 ! translational initiation GO:0006413 23 23 0,000 0,01857907 0,02657023 ! NF-kappaB binding GO:0051059 23 23 0,000 0,01857907 0,02655959 ! vesicle docking GO:0048278 23 23 0,000 0,01857907 0,02654896 ! muscle myosin complex GO:0005859 25 23 0,000 0,01857907 0,02653834 ! vasculogenesis GO:0001570 25 23 0,000 0,01857907 0,02652773 ! regulation of innate immune response GO:0045088 23 23 0,000 0,01857907 0,02651713 ! androgen receptor binding GO:0050681 23 23 0,000 0,01857907 0,02650653 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,01857907 0,02649595 ! sperm motility GO:0030317 23 23 0,000 0,01857907 0,02648537 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,01857907 0,0264748 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,01857907 0,02646424 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,01857907 0,02645369 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 24 23 0,000 0,01857907 0,02644315 ! regulation of behavior GO:0050795 23 23 0,000 0,01857907 0,02643261 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,01857907 0,02642208 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,01857907 0,02641157 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,01857907 0,02640106 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,01857907 0,02639055 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,01857907 0,02638006 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,01857907 0,02636958 ! pallium development GO:0021543 23 23 0,000 0,01857907 0,0263591 ! GABA receptor activity GO:0016917 24 23 0,000 0,01857907 0,02634863 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,01857907 0,02633817 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,01857907 0,02632772 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,01857907 0,02631728 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,01857907 0,02630684 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,01857907 0,02629641 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,01857907 0,026286 ! cell surface binding GO:0043498 25 23 0,000 0,01857907 0,02627559 ! collagen binding GO:0005518 27 23 0,000 0,01857907 0,02626518 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,01857907 0,02625479 ! regulation of amine transport GO:0051952 23 23 0,000 0,01857907 0,0262444 ! tissue homeostasis GO:0001894 24 23 0,000 0,01857907 0,02623403 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,01857907 0,02622366 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,01857907 0,0262133 ! gluconeogenesis GO:0006094 24 23 0,000 0,01857907 0,02620294 ! iron ion transport GO:0006826 24 23 0,000 0,01857907 0,0261926 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,01857907 0,02618226 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,01857907 0,02617193 ! molting cycle process GO:0022404 23 23 0,000 0,01857907 0,02616161 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,01857907 0,0261513 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,01857907 0,026141 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,01857907 0,0261307 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,01857907 0,02612041 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,01857907 0,02611013 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,01857907 0,02609986 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,01857907 0,0260896 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,01857907 0,02607934 ! brush border GO:0005903 25 23 0,000 0,01857907 0,0260691 ! caveola GO:0005901 24 23 0,000 0,01857907 0,02605886 ! gap junction GO:0005921 23 23 0,000 0,01857907 0,02604863 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,01937963 0,02716038 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,01937963 0,02714973 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,01937963 0,02713908 ! protein amino acid acylation GO:0043543 26 24 0,000 0,01937963 0,02712844 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,01937963 0,02711781 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,01937963 0,02710719 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,01937963 0,02709658 ! MHC class I protein complex GO:0042612 24 24 0,000 0,01937963 0,02708597 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 0,000 0,01937963 0,02707537 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,01937963 0,02706478 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,01937963 0,0270542 ! early endosome membrane GO:0031901 26 24 0,000 0,01937963 0,02704363 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,01937963 0,02703307 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,01937963 0,02702251 ! immunoglobulin production GO:0002377 28 24 0,000 0,01937963 0,02701197 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,01937963 0,02700143 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,01937963 0,0269909 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,01937963 0,02698037 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,01937963 0,02696986 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,01937963 0,02695935 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,01937963 0,02694885 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,01937963 0,02693836 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,01937963 0,02692788 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,01937963 0,02691741 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,01937963 0,02690694 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,01937963 0,02689648 ! Z disc GO:0030018 27 24 0,000 0,01937963 0,02688604 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,01937963 0,02687559 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,01937963 0,02686516 ! neuron fate commitment GO:0048663 24 24 0,000 0,01937963 0,02685474 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,01937963 0,02684432 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,01937963 0,02683391 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,01937963 0,02682351 ! glucose transport GO:0015758 24 24 0,000 0,01937963 0,02681312 ! dendrite development GO:0016358 26 24 0,000 0,01937963 0,02680273 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,01937963 0,02679236 ! catechol metabolic process GO:0009712 27 24 0,000 0,01937963 0,02678199 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,01937963 0,02677163 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,01937963 0,02676127 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,01937963 0,02675093 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,01937963 0,02674059 ! synaptogenesis GO:0007416 25 24 0,000 0,01937963 0,02673026 ! selenium binding GO:0008430 24 24 0,000 0,01937963 0,02671994 ! leukocyte proliferation GO:0070661 30 24 0,000 0,01937963 0,02670963 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,01937963 0,02669933 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02017959 0,02779071 ! RNA export from nucleus GO:0006405 27 25 0,000 0,02017959 0,02778 ! phenol metabolic process GO:0018958 28 25 0,000 0,02017959 0,02776929 ! myelination GO:0042552 26 25 0,000 0,02017959 0,0277586 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02017959 0,02774791 ! actin filament GO:0005884 28 25 0,000 0,02017959 0,02773723 ! hexose transport GO:0008645 25 25 0,000 0,02017959 0,02772656 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02017959 0,02771589 ! PML body GO:0016605 28 25 0,000 0,02017959 0,02770524 ! regulation of cellular ketone metabolic process GO:0010565 26 25 0,000 0,02017959 0,02769459 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02017959 0,02768395 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02017959 0,02767332 ! cell fate determination GO:0001709 25 25 0,000 0,02017959 0,02766269 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02017959 0,02765208 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02017959 0,02764147 ! hormone transport GO:0009914 26 25 0,000 0,02017959 0,02763087 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02017959 0,02762028 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02017959 0,0276097 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02017959 0,02759913 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02017959 0,02758856 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02017959 0,027578 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02017959 0,02756745 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02017959 0,02755691 ! zinc ion transport GO:0006829 26 25 0,000 0,02017959 0,02754638 ! heterochromatin GO:0000792 26 25 0,000 0,02017959 0,02753585 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02017959 0,02752533 ! phototransduction GO:0007602 25 25 0,000 0,02017959 0,02751482 ! keratinization GO:0031424 26 25 0,000 0,02017959 0,02750432 ! spinal cord development GO:0021510 25 25 0,000 0,02017959 0,02749383 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02017959 0,02748334 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02017959 0,02747286 ! response to toxin GO:0009636 25 25 0,000 0,02017959 0,02746239 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02017959 0,02745193 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02017959 0,02744148 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02017959 0,02743103 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02017959 0,02742059 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02017959 0,02741016 ! phospholipid transport GO:0015914 26 25 0,000 0,02017959 0,02739974 ! peptidase activator activity GO:0016504 25 25 0,000 0,02017959 0,02738933 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02017959 0,02737892 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02017959 0,02736852 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 0,000 0,02017959 0,02735813 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02017959 0,02734775 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02017959 0,02733737 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02017959 0,02732701 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02017959 0,02731665 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02017959 0,0273063 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02097896 0,02837722 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02097896 0,02836647 ! regeneration GO:0031099 26 26 0,000 0,02097896 0,02835573 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02097896 0,02834501 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02097896 0,02833428 ! ureteric bud development GO:0001657 26 26 0,000 0,02097896 0,02832357 ! neural crest cell development GO:0014032 26 26 0,000 0,02097896 0,02831287 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02097896 0,02830217 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02097896 0,02829148 ! lipid oxidation GO:0034440 26 26 0,000 0,02097896 0,0282808 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02097896 0,02827013 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02097896 0,02825947 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02097896 0,02824881 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02097896 0,02823816 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02097896 0,02822752 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02097896 0,02821689 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02097896 0,02820627 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02097896 0,02819565 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02097896 0,02818504 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02097896 0,02817444 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02097896 0,02816385 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02097896 0,02815327 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02097896 0,02814269 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02097896 0,02813213 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02097896 0,02812156 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02097896 0,02811101 ! chemokine binding GO:0019956 26 26 0,000 0,02097896 0,02810047 ! receptor metabolic process GO:0043112 28 26 0,000 0,02097896 0,02808993 ! nucleotide kinase activity GO:0019201 30 26 0,000 0,02097896 0,0280794 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02097896 0,02806888 ! phospholipase C activity GO:0004629 27 26 0,000 0,02097896 0,02805837 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02097896 0,02804787 ! receptor regulator activity GO:0030545 26 26 0,000 0,02097896 0,02803737 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02097896 0,02802688 ! response to heat GO:0009408 26 26 0,000 0,02097896 0,0280164 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02097896 0,02800592 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02177772 0,02906138 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02177772 0,02905052 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02177772 0,02903967 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02177772 0,02902883 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,02177772 0,029018 ! iron ion homeostasis GO:0055072 27 27 0,000 0,02177772 0,02900718 ! lipoprotein binding GO:0008034 29 27 0,000 0,02177772 0,02899636 ! deaminase activity GO:0019239 27 27 0,000 0,02177772 0,02898555 ! mesoderm formation GO:0001707 28 27 0,000 0,02177772 0,02897476 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02177772 0,02896396 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02177772 0,02895318 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02177772 0,02894241 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02177772 0,02893164 ! integrin complex GO:0008305 28 27 0,000 0,02177772 0,02892088 ! nuclear chromatin GO:0000790 28 27 0,000 0,02177772 0,02891013 ! collagen metabolic process GO:0032963 27 27 0,000 0,02177772 0,02889938 ! post-embryonic development GO:0009791 29 27 0,000 0,02177772 0,02888865 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02177772 0,02887792 ! ovulation cycle process GO:0022602 27 27 0,000 0,02177772 0,0288672 ! SNARE binding GO:0000149 28 27 0,000 0,02177772 0,02885649 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02177772 0,02884579 ! spindle pole GO:0000922 28 27 0,000 0,02177772 0,02883509 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,02177772 0,0288244 ! trans-Golgi network GO:0005802 29 28 0,000 0,02257589 0,02986977 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,02257589 0,02985871 ! cholesterol transport GO:0030301 28 28 0,000 0,02257589 0,02984765 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,02257589 0,0298366 ! formation of primary germ layer GO:0001704 29 28 0,000 0,02257589 0,02982557 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,02257589 0,02981454 ! ovulation cycle GO:0042698 28 28 0,000 0,02257589 0,02980351 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,02257589 0,0297925 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,02257589 0,02978149 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,02257589 0,0297705 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,02257589 0,02975951 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,02257589 0,02974853 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,02257589 0,02973755 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,02257589 0,02972659 ! membrane docking GO:0022406 28 28 0,000 0,02257589 0,02971563 ! sister chromatid segregation GO:0000819 28 28 0,000 0,02257589 0,02970468 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,02257589 0,02969374 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,02257589 0,02968281 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,02257589 0,02967188 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,02257589 0,02966097 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,02257589 0,02965006 ! caspase regulator activity GO:0043028 28 28 0,000 0,02257589 0,02963916 ! ensheathment of neurons GO:0007272 29 28 0,000 0,02257589 0,02962826 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,02257589 0,02961738 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,02257589 0,0296065 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,02257589 0,02959563 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,02257589 0,02958477 ! glycogen metabolic process GO:0005977 29 28 0,000 0,02257589 0,02957392 ! RNA helicase activity GO:0003724 28 28 0,000 0,02257589 0,02956307 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,02257589 0,02955224 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,02257589 0,02954141 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,02337346 0,03057386 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,02337346 0,03056266 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,02337346 0,03055148 ! scavenger receptor activity GO:0005044 30 29 0,000 0,02337346 0,0305403 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,02337346 0,03052913 ! male gonad development GO:0008584 29 29 0,000 0,02337346 0,03051796 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,02337346 0,03050681 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,02337346 0,03049566 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,02337346 0,03048453 ! endocytic vesicle GO:0030139 29 29 0,000 0,02337346 0,0304734 ! Rho GTPase binding GO:0017048 32 29 0,000 0,02337346 0,03046227 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,02337346 0,03045116 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,02337346 0,03044006 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,02337346 0,03042896 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,02337346 0,03041787 ! glucan metabolic process GO:0044042 30 29 0,000 0,02337346 0,03040679 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,02337346 0,03039571 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,02337346 0,03038465 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,02337346 0,03037359 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,02337346 0,03036254 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,02337346 0,0303515 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,02337346 0,03034047 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,02337346 0,03032944 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,02337346 0,03031843 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,02337346 0,03030742 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,02337346 0,03029642 ! detection of visible light GO:0009584 29 29 0,000 0,02337346 0,03028543 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,02337346 0,03027444 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,02337346 0,03026346 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02337346 0,03025249 ! gene silencing GO:0016458 29 29 0,000 0,02337346 0,03024153 ! hormone binding GO:0042562 30 30 0,000 0,02417044 0,03126137 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,02417044 0,03125005 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,02417044 0,03123874 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,02417044 0,03122743 ! acrosomal vesicle GO:0001669 32 30 0,000 0,02417044 0,03121614 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,02417044 0,03120486 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,02417044 0,03119358 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,02417044 0,03118231 ! glutamate receptor activity GO:0008066 33 30 0,000 0,02417044 0,03117105 ! ceramide metabolic process GO:0006672 30 30 0,000 0,02417044 0,03115979 ! cell fate specification GO:0001708 31 30 0,000 0,02417044 0,03114855 ! hexose biosynthetic process GO:0019319 32 30 0,000 0,02417044 0,03113731 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,02417044 0,03112608 ! PDZ domain binding GO:0030165 32 30 0,000 0,02417044 0,03111486 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,02417044 0,03110365 GO:0030131|clathrin adaptor complex, ! negative regulation of cell activation GO:0050866 31 30 0,000 0,02417044 0,03109245 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,02417044 0,03108125 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,02417044 0,03107006 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,02417044 0,03105888 ! drug binding GO:0008144 30 30 0,000 0,02417044 0,03104771 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,02417044 0,03103654 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,02417044 0,03102539 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,02417044 0,03101424 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,02417044 0,0310031 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,02417044 0,03099197 ! aminopeptidase activity GO:0004177 32 30 0,000 0,02417044 0,03098084 ! detection of light stimulus GO:0009583 30 30 0,000 0,02417044 0,03096973 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,02417044 0,03095862 ! regulation of microtubule-based process GO:0032886 32 30 0,000 0,02417044 0,03094752 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,02417044 0,03093643 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,02496682 0,03194428 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,02496682 0,03193284 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,02496682 0,03192141 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,02496682 0,03190999 ! spliceosome assembly GO:0000245 32 31 0,000 0,02496682 0,03189857 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,02496682 0,03188716 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,02496682 0,03187576 ! NAD or NADH binding GO:0051287 31 31 0,000 0,02496682 0,03186437 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,02496682 0,03185298 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,02496682 0,03184161 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,02496682 0,03183024 ! replication fork GO:0005657 32 31 0,000 0,02496682 0,03181888 ! placenta development GO:0001890 31 31 0,000 0,02496682 0,03180753 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,02496682 0,03179618 ! regulation of pH GO:0006885 31 31 0,000 0,02496682 0,03178485 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,02496682 0,03177352 ! acute-phase response GO:0006953 32 31 0,000 0,02496682 0,0317622 ! peptide transport GO:0015833 32 31 0,000 0,02496682 0,03175089 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,02496682 0,03173959 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,02496682 0,03172829 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,02496682 0,031717 ! regulation of protein stability GO:0031647 32 31 0,000 0,02496682 0,03170573 ! sarcolemma GO:0042383 33 31 0,000 0,02496682 0,03169445 ! vesicle localization GO:0051648 32 31 0,000 0,02496682 0,03168319 ! microtubule organizing center part GO:0044450 34 31 0,000 0,02496682 0,03167194 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,0257626 0,03266983 ! DNA helicase activity GO:0003678 34 32 0,000 0,0257626 0,03265823 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,0257626 0,03264664 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,0257626 0,03263506 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,0257626 0,03262349 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,0257626 0,03261192 ! late endosome membrane GO:0031902 32 32 0,000 0,0257626 0,03260037 ! positive regulation of cell development GO:0010720 33 32 0,000 0,0257626 0,03258882 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 0,000 0,0257626 0,03257728 ! hindbrain development GO:0030902 35 32 0,000 0,0257626 0,03256575 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,0257626 0,03255423 ! regulation of muscle development GO:0048634 33 32 0,000 0,0257626 0,03254271 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,0257626 0,0325312 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,0257626 0,0325197 ! response to ionizing radiation GO:0010212 33 32 0,000 0,0257626 0,03250821 ! flagellum GO:0019861 32 32 0,000 0,0257626 0,03249673 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,0257626 0,03248525 ! I band GO:0031674 35 32 0,000 0,0257626 0,03247379 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,0257626 0,03246233 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,0257626 0,03245088 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,0257626 0,03243944 ! adult locomotory behavior GO:0008344 33 32 0,000 0,0257626 0,032428 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,0257626 0,03241658 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,02655779 0,03340537 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,02655779 0,03339361 ! establishment or maintenance of cell polarity GO:0007163 33 33 0,000 0,02655779 0,03338186 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,02655779 0,03337011 ! negative regulation of binding GO:0051100 34 33 0,000 0,02655779 0,03335837 ! organelle envelope lumen GO:0031970 34 33 0,000 0,02655779 0,03334664 ! protein targeting to membrane GO:0006612 35 33 0,000 0,02655779 0,03333492 ! vesicle coat GO:0030120 36 33 0,000 0,02655779 0,03332321 ! endoribonuclease activity GO:0004521 34 33 0,000 0,02655779 0,03331151 ! eye morphogenesis GO:0048592 38 33 0,000 0,02655779 0,03329981 ! embryonic organ development GO:0048568 36 33 0,000 0,02655779 0,03328812 ! monosaccharide biosynthetic process GO:0046364 35 33 0,000 0,02655779 0,03327644 ! glial cell differentiation GO:0010001 33 33 0,000 0,02655779 0,03326477 ! cell junction organization GO:0034330 35 33 0,000 0,02655779 0,0332531 ! tissue remodeling GO:0048771 35 33 0,000 0,02655779 0,03324145 ! segmentation GO:0035282 34 33 0,000 0,02655779 0,0332298 ! steroid hormone receptor binding GO:0035258 33 33 0,000 0,02655779 0,03321816 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,02655779 0,03320653 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,02655779 0,03319491 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,02655779 0,03318329 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,02655779 0,03317169 ! androgen receptor signaling pathway GO:0030521 34 33 0,000 0,02655779 0,03316009 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,02655779 0,0331485 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,02655779 0,03313692 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,02735238 0,03411643 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,02735238 0,03410452 GO:0015144|carbohydrate transmembrane transporter activity, ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,02735238 0,03409262 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,02735238 0,03408072 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,02735238 0,03406883 ! telencephalon development GO:0021537 34 34 0,000 0,02735238 0,03405695 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,02735238 0,03404508 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,02735238 0,03403322 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,02735238 0,03402137 ! collagen GO:0005581 35 34 0,000 0,02735238 0,03400952 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,02735238 0,03399768 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,02735238 0,03398585 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,02735238 0,03397403 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,02735238 0,03396222 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,02735238 0,03395042 ! spermatid development GO:0007286 34 34 0,000 0,02735238 0,03393862 ! BMP signaling pathway GO:0030509 35 34 0,000 0,02735238 0,03392683 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,02735238 0,03391505 ! positive regulation of DNA metabolic process GO:0051054 40 35 0,000 0,02814638 0,03488744 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,02814638 0,03487533 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,02814638 0,03486324 ! vesicle lumen GO:0031983 37 35 0,000 0,02814638 0,03485115 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,02814638 0,03483907 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,02814638 0,034827 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,02814638 0,03481493 ! cytokine production GO:0001816 35 35 0,000 0,02814638 0,03480288 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,02814638 0,03479083 ! embryonic pattern specification GO:0009880 36 35 0,000 0,02814638 0,03477879 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,02814638 0,03476676 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,02814638 0,03475474 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,02814638 0,03474273 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,02814638 0,03473072 ! phagocytosis GO:0006909 37 35 0,000 0,02814638 0,03471873 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,02814638 0,03470674 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,02814638 0,03469476 ! ion transmembrane transport GO:0034220 35 35 0,000 0,02814638 0,03468279 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,02814638 0,03467082 ! oxygen binding GO:0019825 36 35 0,000 0,02814638 0,03465887 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,02814638 0,03464692 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,02814638 0,03463498 ! peripheral nervous system development GO:0007422 37 35 0,000 0,02814638 0,03462305 ! polyol metabolic process GO:0019751 36 35 0,000 0,02814638 0,03461113 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 0,000 0,02893978 0,03557451 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of hormone secretion GO:0046883 38 36 0,000 0,02893978 0,03556227 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,02893978 0,03555004 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,02893978 0,03553781 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,02893978 0,0355256 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,02893978 0,03551339 ! regulation of proteolysis GO:0030162 37 36 0,000 0,02893978 0,03550119 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,02893978 0,035489 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,02893978 0,03547681 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,02893978 0,03546464 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,02893978 0,03545247 ! spermatid differentiation GO:0048515 36 36 0,000 0,02893978 0,03544031 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,02893978 0,03542817 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,02893978 0,03541602 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,02893978 0,03540389 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,02893978 0,03539177 ! neuropeptide binding GO:0042923 36 36 0,000 0,02893978 0,03537965 ! organic anion transport GO:0015711 37 36 0,000 0,02893978 0,03536754 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,02893978 0,03535544 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,02893978 0,03534335 ! antigen binding GO:0003823 36 36 0,000 0,02893978 0,03533127 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,02893978 0,03531919 ! cytokinesis GO:0000910 40 36 0,000 0,02893978 0,03530713 ! coated pit GO:0005905 42 36 0,000 0,02893978 0,03529507 ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,02973259 0,0362496 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,02973259 0,03623723 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,02973259 0,03622487 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,02973259 0,03621251 ! biopolymer methylation GO:0043414 42 37 0,000 0,02973259 0,03620016 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,02973259 0,03618783 ! protein homooligomerization GO:0051260 38 37 0,000 0,02973259 0,0361755 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,02973259 0,03616318 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,02973259 0,03615086 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,02973259 0,03613856 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,02973259 0,03612626 ! amino acid binding GO:0016597 40 37 0,000 0,02973259 0,03611397 ! maintenance of protein location GO:0045185 38 37 0,000 0,02973259 0,03610169 ! maintenance of location in cell GO:0051651 38 37 0,000 0,02973259 0,03608942 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,02973259 0,03607716 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,02973259 0,03606491 ! ear morphogenesis GO:0042471 39 38 0,000 0,03052481 0,03701327 ! odontogenesis GO:0042476 40 38 0,000 0,03052481 0,03700071 ! organic ether metabolic process GO:0018904 39 38 0,000 0,03052481 0,03698815 ! alcohol biosynthetic process GO:0046165 40 38 0,000 0,03052481 0,03697561 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,03052481 0,03696307 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,03052481 0,03695054 ! B cell differentiation GO:0030183 40 38 0,000 0,03052481 0,03693802 ! clathrin coat GO:0030118 43 38 0,000 0,03052481 0,0369255 ! regulation of endocytosis GO:0030100 39 38 0,000 0,03052481 0,036913 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,03052481 0,0369005 ! cell growth GO:0016049 40 38 0,000 0,03052481 0,03688802 ! positive regulation of defense response GO:0031349 38 38 0,000 0,03052481 0,03687554 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,03052481 0,03686307 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,03052481 0,0368506 ! learning GO:0007612 42 38 0,000 0,03052481 0,03683815 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,03052481 0,03682571 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,03052481 0,03681327 ! endosome transport GO:0016197 40 38 0,000 0,03052481 0,03680084 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,03052481 0,03678842 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,03052481 0,03677601 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,03052481 0,0367636 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,03052481 0,03675121 ! pigment metabolic process GO:0042440 42 38 0,000 0,03052481 0,03673882 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,03052481 0,03672644 ! RNA modification GO:0009451 39 38 0,000 0,03052481 0,03671407 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03131643 0,03765353 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03131643 0,03764085 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03131643 0,03762819 ! keratin filament GO:0045095 41 39 0,000 0,03131643 0,03761553 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03131643 0,03760288 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03131643 0,03759024 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03131643 0,03757761 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03131643 0,03756499 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03131643 0,03755238 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03131643 0,03753977 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03131643 0,03752717 ! viral infectious cycle GO:0019058 39 39 0,000 0,03131643 0,03751458 ! mammary gland development GO:0030879 41 39 0,000 0,03131643 0,037502 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03131643 0,03748943 ! amine receptor activity GO:0008227 41 39 0,000 0,03131643 0,03747687 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,03131643 0,03746431 ! monosaccharide binding GO:0048029 39 39 0,000 0,03131643 0,03745177 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03131643 0,03743923 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 0,000 0,03210746 0,03837207 ! response to estrogen stimulus GO:0043627 41 40 0,000 0,03210746 0,03835923 ! peptide metabolic process GO:0006518 41 40 0,000 0,03210746 0,0383464 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,03210746 0,03833358 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,03210746 0,03832077 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03210746 0,03830797 ! regulation of gene expression, epigenetic GO:0040029 43 40 0,000 0,03210746 0,03829517 ! neuron migration GO:0001764 42 40 0,000 0,03210746 0,03828239 ! nuclear export GO:0051168 42 40 0,000 0,03210746 0,03826961 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03210746 0,03825684 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03210746 0,03824408 ! gliogenesis GO:0042063 40 40 0,000 0,03210746 0,03823133 ! feeding behavior GO:0007631 40 40 0,000 0,03210746 0,03821858 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,03210746 0,03820585 ! nucleus organization GO:0006997 40 40 0,000 0,03210746 0,03819312 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03210746 0,0381804 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03210746 0,03816769 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,03210746 0,03815499 ! chromatin remodeling GO:0006338 43 40 0,000 0,03210746 0,0381423 ! response to insulin stimulus GO:0032868 45 40 0,000 0,03210746 0,03812961 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,0328979 0,03905532 ! positive regulation of binding GO:0051099 42 41 0,000 0,0328979 0,03904234 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,0328979 0,03902937 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,0328979 0,03901641 ! regulation of translational initiation GO:0006446 41 41 0,000 0,0328979 0,03900346 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,0328979 0,03899051 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,0328979 0,03897757 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,0328979 0,03896465 ! exonuclease activity GO:0004527 42 41 0,000 0,0328979 0,03895173 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,0328979 0,03893882 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,0328979 0,03892591 ! hydro-lyase activity GO:0016836 44 41 0,000 0,0328979 0,03891302 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,0328979 0,03890013 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,0328979 0,03888726 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,0328979 0,03887439 ! metal cluster binding GO:0051540 43 41 0,000 0,0328979 0,03886153 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,0328979 0,03884868 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,0328979 0,03883584 ! double-strand break repair GO:0006302 41 41 0,000 0,0328979 0,038823 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,0328979 0,03881018 ! RNA catabolic process GO:0006401 44 42 0,000 0,03368775 0,03972885 ! organellar ribosome GO:0000313 43 42 0,000 0,03368775 0,03971573 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,03368775 0,03970262 ! damaged DNA binding GO:0003684 42 42 0,000 0,03368775 0,03968953 ! MHC protein complex GO:0042611 42 42 0,000 0,03368775 0,03967644 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,03368775 0,03966335 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,03368775 0,03965028 ! positive regulation of growth GO:0045927 42 42 0,000 0,03368775 0,03963722 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,03368775 0,03962416 ! chemokine activity GO:0008009 42 42 0,000 0,03368775 0,03961111 ! ruffle GO:0001726 44 42 0,000 0,03368775 0,03959807 ! pigmentation GO:0043473 46 42 0,000 0,03368775 0,03958504 ! developmental growth GO:0048589 42 42 0,000 0,03368775 0,03957202 ! methylation GO:0032259 47 42 0,000 0,03368775 0,03955901 ! regulation of tube size GO:0035150 44 42 0,000 0,03368775 0,03954601 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,03368775 0,03953301 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,03368775 0,03952002 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,03368775 0,03950704 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,034477 0,04041936 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,034477 0,0404061 ! keratinocyte differentiation GO:0030216 46 43 0,000 0,034477 0,04039284 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,034477 0,04037959 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,034477 0,04036636 ! sulfotransferase activity GO:0008146 44 43 0,000 0,034477 0,04035312 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,034477 0,0403399 ! channel regulator activity GO:0016247 46 43 0,000 0,034477 0,04032669 ! histone modification GO:0016570 44 43 0,000 0,034477 0,04031349 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,034477 0,04030029 ! synaptosome GO:0019717 47 43 0,000 0,034477 0,0402871 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,03526567 0,04119519 ! platelet alpha granule GO:0031091 46 44 0,000 0,03526567 0,04118172 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,03526567 0,04116826 ! regulation of ossification GO:0030278 48 44 0,000 0,03526567 0,04115481 ! cell recognition GO:0008037 46 44 0,000 0,03526567 0,04114136 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,03526567 0,04112792 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,03526567 0,0411145 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,03526567 0,04110108 ! cellular component disassembly GO:0022411 45 44 0,000 0,03526567 0,04108767 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,03526567 0,04107427 ! regulation of ion transport GO:0043269 47 44 0,000 0,03526567 0,04106088 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 0,000 0,03526567 0,04104749 ! inner ear development GO:0048839 46 44 0,000 0,03526567 0,04103412 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,03526567 0,04102075 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,03526567 0,04100739 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,03526567 0,04099404 ! chemokine receptor binding GO:0042379 44 44 0,000 0,03526567 0,0409807 ! regulation of action potential GO:0001508 50 45 0,000 0,03605374 0,04188286 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,03605374 0,04186924 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,03605374 0,04185563 ! response to temperature stimulus GO:0009266 45 45 0,000 0,03605374 0,04184203 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,03605374 0,04182843 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,03605374 0,04181485 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,03605374 0,04180127 ! excretion GO:0007588 46 45 0,000 0,03605374 0,04178771 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,03605374 0,04177415 ! JNK cascade GO:0007254 45 45 0,000 0,03605374 0,0417606 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,03605374 0,04174706 ! regulation of cell shape GO:0008360 46 45 0,000 0,03605374 0,04173352 ! microbody part GO:0044438 46 45 0,000 0,03605374 0,04172 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,03684123 0,04261744 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,03684123 0,04260364 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of inflammatory response GO:0050727 46 46 0,000 0,03684123 0,04258984 ! transport vesicle GO:0030133 49 46 0,000 0,03684123 0,04257606 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,03684123 0,04256229 ! synapse organization GO:0050808 51 46 0,000 0,03684123 0,04254852 ! nuclear matrix GO:0016363 49 46 0,000 0,03684123 0,04253476 ! striated muscle contraction GO:0006941 49 46 0,000 0,03684123 0,04252102 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,03684123 0,04250728 ! antioxidant activity GO:0016209 47 46 0,000 0,03684123 0,04249355 ! activation of caspase activity GO:0006919 49 46 0,000 0,03684123 0,04247983 ! aging GO:0007568 48 46 0,000 0,03684123 0,04246612 ! male sex differentiation GO:0046661 46 46 0,000 0,03684123 0,04245241 ! coated vesicle membrane GO:0030662 49 46 0,000 0,03684123 0,04243872 ! covalent chromatin modification GO:0016569 47 46 0,000 0,03684123 0,04242503 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,03684123 0,04241136 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,03762812 0,04330326 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,03762812 0,04328931 ! carbohydrate transport GO:0008643 47 47 0,000 0,03762812 0,04327537 ! proteasome complex GO:0000502 48 47 0,000 0,03762812 0,04326144 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,03762812 0,04324751 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,03762812 0,0432336 ! vesicle organization GO:0016050 50 47 0,000 0,03762812 0,04321969 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,03762812 0,0432058 ! cell cortex part GO:0044448 51 47 0,000 0,03762812 0,04319191 ! lipid modification GO:0030258 49 48 0,000 0,03841443 0,04408031 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,03841443 0,04406615 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,03841443 0,044052 ! epidermal cell differentiation GO:0009913 51 48 0,000 0,03841443 0,04403786 ! mitochondrial transport GO:0006839 49 48 0,000 0,03841443 0,04402372 ! viral reproductive process GO:0022415 52 48 0,000 0,03841443 0,0440096 ! leukocyte migration GO:0050900 49 48 0,000 0,03841443 0,04399548 ! neuromuscular process GO:0050905 49 48 0,000 0,03841443 0,04398138 ! gastrulation GO:0007369 50 48 0,000 0,03841443 0,04396728 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,03841443 0,04395319 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,03841443 0,04393912 ! B cell mediated immunity GO:0019724 51 48 0,000 0,03841443 0,04392505 ! protein N-terminus binding GO:0047485 51 48 0,000 0,03841443 0,04391099 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,03920014 0,04479479 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,03920014 0,04478046 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,03920014 0,04476614 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,03920014 0,04475183 ! ribonuclease activity GO:0004540 50 49 0,000 0,03920014 0,04473752 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,03920014 0,04472323 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,03920014 0,04470895 ! lamellipodium GO:0030027 53 49 0,000 0,03920014 0,04469467 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,03920014 0,04468041 ! nucleosome GO:0000786 49 49 0,000 0,03920014 0,04466615 ! kinetochore GO:0000776 50 49 0,000 0,03920014 0,0446519 ! membrane fusion GO:0006944 51 49 0,000 0,03920014 0,04463766 ! endocrine system development GO:0035270 49 49 0,000 0,03920014 0,04462343 ! RNA elongation GO:0006354 51 49 0,000 0,03920014 0,04460921 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,03998527 0,04548818 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,03998527 0,0454737 ! basement membrane GO:0005604 51 50 0,000 0,03998527 0,04545922 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,03998527 0,04544475 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,03998527 0,04543029 ! maintenance of location GO:0051235 51 50 0,000 0,03998527 0,04541584 ! nuclear periphery GO:0034399 53 50 0,000 0,03998527 0,0454014 ! cell redox homeostasis GO:0045454 51 50 0,000 0,03998527 0,04538697 ! integrin binding GO:0005178 53 50 0,000 0,03998527 0,04537255 ! regulation of DNA replication GO:0006275 56 50 0,000 0,03998527 0,04535813 ! amino acid activation GO:0043038 50 50 0,000 0,03998527 0,04534373 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,03998527 0,04532933 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,04076981 0,04620406 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,04076981 0,0461894 ! late endosome GO:0005770 51 51 0,000 0,04076981 0,04617475 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,04076981 0,04616011 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,04076981 0,04614548 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,04076981 0,04613086 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,04076981 0,04611625 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,04076981 0,04610164 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,04076981 0,04608705 ! heart morphogenesis GO:0003007 54 51 0,000 0,04076981 0,04607247 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,04076981 0,04605789 ! antiporter activity GO:0015297 52 51 0,000 0,04076981 0,04604333 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,04155376 0,04691384 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,04155376 0,04689902 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,04155376 0,0468842 ! DNA damage response, signal transduction GO:0042770 58 52 0,000 0,04155376 0,04686939 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,04155376 0,04685459 ! cell maturation GO:0048469 55 52 0,000 0,04155376 0,0468398 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,04155376 0,04682502 ! regulation of actin filament length GO:0030832 53 52 0,000 0,04155376 0,04681025 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,04155376 0,04679549 ! chloride transport GO:0006821 53 52 0,000 0,04155376 0,04678073 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,04155376 0,04676599 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,04155376 0,04675126 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,04155376 0,04673653 ! negative regulation of cytoskeleton organization GO:0051494 57 52 0,000 0,04155376 0,04672182 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,04155376 0,04670711 ! small ribosomal subunit GO:0015935 52 52 0,000 0,04155376 0,04669241 ! cytokine receptor activity GO:0004896 53 52 0,000 0,04155376 0,04667772 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,04233713 0,04754273 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,04233713 0,04752778 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,04233713 0,04751285 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,04233713 0,04749792 ! synaptic vesicle GO:0008021 57 53 0,000 0,04233713 0,047483 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,04233713 0,04746809 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,04233713 0,0474532 ! cell projection assembly GO:0030031 56 53 0,000 0,04233713 0,04743831 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,04233713 0,04742343 ! proton transport GO:0015992 53 53 0,000 0,04233713 0,04740855 ! mRNA binding GO:0003729 55 53 0,000 0,04233713 0,04739369 ! single fertilization GO:0007338 55 53 0,000 0,04233713 0,04737884 ! axon GO:0030424 58 54 0,000 0,0431199 0,04823972 ! heat shock protein binding GO:0031072 54 54 0,000 0,0431199 0,04822461 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,0431199 0,04820951 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,0431199 0,04819442 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,0431199 0,04817934 ! tRNA processing GO:0008033 55 54 0,000 0,0431199 0,04816427 ! regulation of cellular response to stress GO:0080135 57 54 0,000 0,0431199 0,04814921 ! growth factor receptor binding GO:0070851 56 54 0,000 0,0431199 0,04813416 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,0431199 0,04811912 ! DNA catabolic process GO:0006308 55 54 0,000 0,0431199 0,04810409 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,0431199 0,04808906 ! regulation of cellular component size GO:0032535 56 55 0,000 0,04390209 0,04894611 ! response to peptide hormone stimulus GO:0043434 60 55 0,000 0,04390209 0,04893083 ! hydrogen transport GO:0006818 55 55 0,000 0,04390209 0,04891556 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,04390209 0,04890031 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,04390209 0,04888506 ! large ribosomal subunit GO:0015934 56 55 0,000 0,04390209 0,04886982 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,04390209 0,04885459 ! positive regulation of secretion GO:0051047 60 56 0,000 0,0446837 0,04970888 ! regulation of mitosis GO:0007088 56 56 0,000 0,0446837 0,04969339 GO:0051783|regulation of nuclear division, ! actin filament organization GO:0007015 59 56 0,000 0,0446837 0,04967792 ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,0446837 0,04966246 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,0446837 0,04964701 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,0446837 0,04963157 ! cartilage development GO:0051216 59 56 0,000 0,0446837 0,04961614 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,0446837 0,04960071 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,0446837 0,0495853 ! mesoderm development GO:0007498 57 56 0,000 0,0446837 0,04956989 ! camera-type eye development GO:0043010 59 56 0,000 0,0446837 0,0495545 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,04546472 0,050405 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,04546472 0,05038936 ! chromosome segregation GO:0007059 59 57 0,000 0,04546472 0,05037372 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,04546472 0,0503581 ! kidney development GO:0001822 60 57 0,000 0,04546472 0,05034248 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,04546472 0,05032688 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,04546472 0,05031128 ! adult behavior GO:0030534 60 57 0,000 0,04546472 0,0502957 ! steroid hormone receptor signaling pathway GO:0030518 58 57 0,000 0,04546472 0,05028012 ! myosin complex GO:0016459 59 57 0,000 0,04546472 0,05026455 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,04624515 0,05111156 ! lysosomal membrane GO:0005765 59 58 0,000 0,04624515 0,05109574 ! extracellular matrix organization GO:0030198 59 58 0,000 0,04624515 0,05107994 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,04624515 0,05106414 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,04624515 0,05104836 ! detection of external stimulus GO:0009581 59 58 0,000 0,04624515 0,05103258 ! secondary metabolic process GO:0019748 59 58 0,000 0,04624515 0,05101682 ! translation initiation factor activity GO:0003743 58 58 0,000 0,04624515 0,05100106 ! molecular adaptor activity GO:0060090 65 59 0,000 0,047025 0,0518451 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,047025 0,0518291 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,047025 0,05181311 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,047025 0,05179712 ! regulation of heart contraction GO:0008016 62 59 0,000 0,047025 0,05178115 ! copper ion binding GO:0005507 61 59 0,000 0,047025 0,05176519 ! activation of immune response GO:0002253 68 59 0,000 0,047025 0,05174924 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,047025 0,0517333 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,047025 0,05171736 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,047025 0,05170144 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,047025 0,05168553 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,04780426 0,05252586 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,04780426 0,0525097 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,04780426 0,05249355 GO:0005923|tight junction, ! regulation of lipid metabolic process GO:0019216 63 60 0,000 0,04780426 0,05247741 ! myeloid cell differentiation GO:0030099 64 60 0,000 0,04780426 0,05246129 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,04780426 0,05244517 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,04780426 0,05242906 ! lymphocyte mediated immunity GO:0002449 63 60 0,000 0,04780426 0,05241297 ! chloride channel activity GO:0005254 61 60 0,000 0,04780426 0,05239688 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 0,000 0,04858294 0,05323403 ! cell cycle checkpoint GO:0000075 64 61 0,000 0,04858294 0,0532177 ! fertilization GO:0009566 64 61 0,000 0,04858294 0,05320138 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,04858294 0,05318507 ! gonad development GO:0008406 61 61 0,000 0,04858294 0,05316877 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,04858294 0,05315248 ! regulation of immune effector process GO:0002697 65 61 0,000 0,04858294 0,0531362 ! amine catabolic process GO:0009310 68 62 0,000 0,04936104 0,05397069 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,04936104 0,05395417 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,04936104 0,05393766 ! coated membrane GO:0048475 67 62 0,000 0,04936104 0,05392116 GO:0030117|membrane coat, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,04936104 0,05390467 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,04936104 0,05388819 ! germ cell development GO:0007281 62 62 0,000 0,04936104 0,05387172 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,04936104 0,05385526 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,05013855 0,05468686 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,05013855 0,05467016 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,05013855 0,05465347 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,05013855 0,05463679 ! transition metal ion transport GO:0000041 65 63 0,000 0,05013855 0,05462013 ! appendage morphogenesis GO:0035107 67 63 0,000 0,05013855 0,05460347 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,05013855 0,05458682 ! cellular defense response GO:0006968 64 63 0,000 0,05013855 0,05457018 ! B cell activation GO:0042113 66 63 0,000 0,05013855 0,05455356 ! antigen processing and presentation GO:0019882 64 63 0,000 0,05013855 0,05453694 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,05013855 0,05452033 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 0,000 0,05013855 0,05450374 ! organelle localization GO:0051640 66 63 0,000 0,05013855 0,05448715 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,05091548 0,05531463 ! lung development GO:0030324 65 64 0,000 0,05091548 0,05529781 ! respiratory chain GO:0070469 66 64 0,000 0,05091548 0,05528099 ! developmental maturation GO:0021700 67 64 0,000 0,05091548 0,05526419 ! amino acid transport GO:0006865 64 64 0,000 0,05091548 0,0552474 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 0,000 0,05091548 0,05523062 ! anion channel activity GO:0005253 65 64 0,000 0,05091548 0,05521384 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,05169183 0,05603871 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,05169183 0,05602171 ! nuclear pore GO:0005643 69 65 0,000 0,05169183 0,05600471 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,05169183 0,05598772 ! rhythmic process GO:0048511 66 65 0,000 0,05169183 0,05597075 ! regulation of lipase activity GO:0060191 67 65 0,000 0,05169183 0,05595378 ! adaptive immune response GO:0002250 68 65 0,000 0,05169183 0,05593683 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,05169183 0,05591988 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,05169183 0,05590295 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 0,000 0,05169183 0,05588602 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,05169183 0,05586911 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,05169183 0,0558522 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,0524676 0,05667326 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,0524676 0,05665612 ! urogenital system development GO:0001655 69 66 0,000 0,0524676 0,05663899 ! response to steroid hormone stimulus GO:0048545 69 66 0,000 0,0524676 0,05662187 ! diacylglycerol binding GO:0019992 71 66 0,000 0,0524676 0,05660477 ! amine binding GO:0043176 70 66 0,000 0,0524676 0,05658767 ! response to nutrient GO:0007584 67 66 0,000 0,0524676 0,05657059 ! acetyltransferase activity GO:0016407 68 66 0,000 0,0524676 0,05655351 ! respiratory tube development GO:0030323 68 67 0,000 0,05324278 0,05737175 ! mRNA transport GO:0051028 70 67 0,000 0,05324278 0,05735444 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,05324278 0,05733714 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,05324278 0,05731986 ! regulation of caspase activity GO:0043281 70 67 0,000 0,05324278 0,05730258 ! Ras GTPase binding GO:0017016 70 67 0,000 0,05324278 0,05728532 ! humoral immune response GO:0006959 70 67 0,000 0,05324278 0,05726806 ! nuclear hormone receptor binding GO:0035257 68 67 0,000 0,05324278 0,05725082 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 0,000 0,05324278 0,05723358 ! ubiquitin ligase complex GO:0000151 71 67 0,000 0,05324278 0,05721636 ! nucleosome assembly GO:0006334 69 67 0,000 0,05324278 0,05719915 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,05324278 0,05718194 ! muscle cell differentiation GO:0042692 68 68 0,000 0,05401738 0,05799641 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,05401738 0,05797898 ! protein import into nucleus GO:0006606 72 68 0,000 0,05401738 0,05796156 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,05401738 0,05794415 ! regulation of actin cytoskeleton organization GO:0032956 74 68 0,000 0,05401738 0,05792675 ! protein-DNA complex GO:0032993 69 68 0,000 0,05401738 0,05790936 ! learning or memory GO:0007611 72 68 0,000 0,05401738 0,05789198 ! chloride ion binding GO:0031404 70 68 0,000 0,05401738 0,05787461 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,05401738 0,05785725 ! chromatin assembly GO:0031497 70 68 0,000 0,05401738 0,0578399 ! leukocyte mediated immunity GO:0002443 71 68 0,000 0,05401738 0,05782256 ! extrinsic to membrane GO:0019898 68 68 0,000 0,05401738 0,05780523 ! calcium channel activity GO:0005262 73 68 0,000 0,05401738 0,05778792 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,05401738 0,05777061 ! respiratory system development GO:0060541 69 68 0,000 0,05401738 0,05775331 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,05401738 0,05773603 ! regulation of endopeptidase activity GO:0052548 72 69 0,000 0,0547914 0,05854581 ! eye development GO:0001654 74 69 0,000 0,0547914 0,0585283 ! positive regulation of ligase activity GO:0051351 71 69 0,000 0,0547914 0,05851079 ! sarcomere GO:0030017 75 69 0,000 0,0547914 0,0584933 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,0547914 0,05847582 ! axon guidance GO:0007411 74 69 0,000 0,0547914 0,05845835 ! focal adhesion GO:0005925 75 69 0,000 0,0547914 0,05844089 ! regulation of DNA binding GO:0051101 72 70 0,000 0,05556484 0,05924815 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,05556484 0,05923046 ! early endosome GO:0005769 79 70 0,000 0,05556484 0,05921279 ! response to hypoxia GO:0001666 76 70 0,000 0,05556484 0,05919512 ! nuclear import GO:0051170 74 70 0,000 0,05556484 0,05917747 ! female pregnancy GO:0007565 71 70 0,000 0,05556484 0,05915982 ! rRNA processing GO:0006364 70 70 0,000 0,05556484 0,05914219 ! cytosolic ribosome GO:0022626 70 70 0,000 0,05556484 0,05912457 ! cell cortex GO:0005938 74 70 0,000 0,05556484 0,05910696 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,0563377 0,05991124 ! FAD binding GO:0050660 72 71 0,000 0,0563377 0,0598934 ! response to oxygen levels GO:0070482 77 71 0,000 0,0563377 0,05987558 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,0563377 0,05985776 ! defense response to bacterium GO:0042742 71 71 0,000 0,0563377 0,05983996 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,0563377 0,05982216 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,0563377 0,05980438 ! reproductive structure development GO:0048608 71 71 0,000 0,0563377 0,05978661 ! neurotransmitter transport GO:0006836 73 71 0,000 0,0563377 0,05976885 ! regulation of actin filament-based process GO:0032970 77 71 0,000 0,0563377 0,05975109 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,0563377 0,05973335 ! phospholipase activity GO:0004620 75 71 0,000 0,0563377 0,05971562 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,0563377 0,0596979 ! cell projection part GO:0044463 75 71 0,000 0,0563377 0,05968019 ! amine biosynthetic process GO:0009309 75 72 0,000 0,05710998 0,06048035 ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,05710998 0,06046242 ! acute inflammatory response GO:0002526 76 72 0,000 0,05710998 0,0604445 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,05710998 0,06042659 ! lipid transporter activity GO:0005319 77 72 0,000 0,05710998 0,06040869 ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 0,000 0,05710998 0,06039081 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,05710998 0,06037293 ! negative regulation of transport GO:0051051 74 73 0,000 0,05788168 0,06117061 ! vacuolar membrane GO:0005774 74 73 0,000 0,05788168 0,06115251 ! rRNA metabolic process GO:0016072 73 73 0,000 0,05788168 0,06113443 ! negative regulation of organelle organization GO:0010639 78 73 0,000 0,05788168 0,06111635 ! regulation of protein transport GO:0051223 77 73 0,000 0,05788168 0,06109828 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,05788168 0,06108023 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,05788168 0,06106218 ! hormone receptor binding GO:0051427 75 73 0,000 0,05788168 0,06104415 ! nucleosome organization GO:0034728 76 74 0,000 0,05865281 0,06183914 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,05865281 0,06182089 ! pore complex GO:0046930 78 74 0,000 0,05865281 0,06180265 ! regulation of peptidase activity GO:0052547 78 74 0,000 0,05865281 0,06178442 ! protein localization in nucleus GO:0034504 78 74 0,000 0,05865281 0,0617662 ! myofibril GO:0030016 80 74 0,000 0,05865281 0,06174799 ! regulation of blood pressure GO:0008217 76 74 0,000 0,05865281 0,06172979 ! apical junction complex GO:0043296 74 74 0,000 0,05865281 0,0617116 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,05865281 0,06169342 ! membrane raft GO:0045121 78 74 0,000 0,05865281 0,06167526 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,05865281 0,0616571 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,05865281 0,06163896 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,05865281 0,06162082 ! nuclear chromosome part GO:0044454 76 74 0,000 0,05865281 0,0616027 ! response to drug GO:0042493 77 75 0,000 0,05942335 0,06239364 ! small GTPase binding GO:0031267 78 75 0,000 0,05942335 0,0623753 ! regulation of catabolic process GO:0009894 80 75 0,000 0,05942335 0,06235697 ! cell-substrate junction GO:0030055 82 75 0,000 0,05942335 0,06233865 ! establishment of RNA localization GO:0051236 78 75 0,000 0,05942335 0,06232035 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,05942335 0,06230205 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,05942335 0,06228376 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,05942335 0,06226549 ! structural constituent of cytoskeleton GO:0005200 81 75 0,000 0,05942335 0,06224722 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,06019331 0,06303529 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,06019331 0,06301681 ! regulation of ligase activity GO:0051340 78 76 0,000 0,06019331 0,06299834 ! vitamin metabolic process GO:0006766 77 76 0,000 0,06019331 0,06297988 ! inorganic anion transport GO:0015698 78 76 0,000 0,06019331 0,06296143 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,06019331 0,06294299 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,06019331 0,06292457 ! T cell activation GO:0042110 82 76 0,000 0,06019331 0,06290615 ! digestion GO:0007586 80 76 0,000 0,06019331 0,06288775 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,06019331 0,06286936 ! cilium GO:0005929 77 76 0,000 0,06019331 0,06285097 ! contractile fiber part GO:0044449 82 76 0,000 0,06019331 0,0628326 ! regulation of adenylate cyclase activity GO:0045761 80 77 0,000 0,0609627 0,06361713 ! RNA localization GO:0006403 80 77 0,000 0,0609627 0,06359854 ! nuclear speck GO:0016607 80 77 0,000 0,0609627 0,06357997 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,0609627 0,0635614 ! endonuclease activity GO:0004519 80 77 0,000 0,0609627 0,06354285 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,0609627 0,06352431 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,0609627 0,06350578 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,0609627 0,06348726 ! vacuolar part GO:0044437 78 77 0,000 0,0609627 0,06346875 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,06173151 0,06425043 ! potassium channel complex GO:0034705 81 78 0,000 0,06173151 0,06423171 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,06173151 0,064213 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,06173151 0,0641943 ! blood coagulation GO:0007596 81 78 0,000 0,06173151 0,06417561 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,06249974 0,06495535 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,06249974 0,06493645 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,06249974 0,06491756 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,06249974 0,06489869 ! regulation of cyclase activity GO:0031279 82 79 0,000 0,06249974 0,06487982 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,06249974 0,06486097 ! regulation of T cell activation GO:0050863 84 79 0,000 0,06249974 0,06484212 ! regulation of cAMP biosynthetic process GO:0030817 82 79 0,000 0,06249974 0,06482329 ! exocytosis GO:0006887 81 79 0,000 0,06249974 0,06480447 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,06249974 0,06478566 ! regulation of protein localization GO:0032880 83 79 0,000 0,06249974 0,06476686 ! regulation of DNA metabolic process GO:0051052 90 80 0,000 0,0632674 0,06554334 ! GTPase binding GO:0051020 83 80 0,000 0,0632674 0,06552433 ! regulation of cell cycle process GO:0010564 84 80 0,000 0,0632674 0,06550533 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,0632674 0,06548634 ! regulation of lyase activity GO:0051339 83 80 0,000 0,0632674 0,06546737 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,0632674 0,0654484 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,0632674 0,06542945 ! monooxygenase activity GO:0004497 82 80 0,000 0,0632674 0,06541051 ! condensed chromosome GO:0000793 82 80 0,000 0,0632674 0,06539157 ! contractile fiber GO:0043292 86 80 0,000 0,0632674 0,06537265 ! protein ubiquitination GO:0016567 86 80 0,000 0,0632674 0,06535374 ! ossification GO:0001503 85 81 0,000 0,06403448 0,06612699 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 0,000 0,06403448 0,06610787 ! sterol metabolic process GO:0016125 83 81 0,000 0,06403448 0,06608877 ! regulation of cAMP metabolic process GO:0030814 84 81 0,000 0,06403448 0,06606967 ! protein binding, bridging GO:0030674 86 81 0,000 0,06403448 0,06605059 ! regulation of neurological system process GO:0031644 83 81 0,000 0,06403448 0,06603151 ! protein transporter activity GO:0008565 85 82 0,000 0,06480099 0,06680263 ! positive regulation of immune response GO:0050778 91 82 0,000 0,06480099 0,06678335 ! regulation of defense response GO:0031347 82 82 0,000 0,06480099 0,06676408 ! bone development GO:0060348 86 82 0,000 0,06480099 0,06674483 ! carboxylesterase activity GO:0004091 86 82 0,000 0,06480099 0,06672558 ! transcription initiation GO:0006352 86 82 0,000 0,06480099 0,06670635 ! mitochondrion organization GO:0007005 86 83 0,000 0,06556691 0,06747535 ! organelle outer membrane GO:0031968 87 83 0,000 0,06556691 0,06745591 ! cell leading edge GO:0031252 90 83 0,000 0,06556691 0,06743648 ! SH3 domain binding GO:0017124 97 83 0,000 0,06556691 0,06741706 ! hemostasis GO:0007599 86 83 0,000 0,06556691 0,06739765 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,06556691 0,06737826 ! heparin binding GO:0008201 90 83 0,000 0,06556691 0,06735888 ! amine transport GO:0015837 83 83 0,000 0,06556691 0,0673395 ! extracellular matrix part GO:0044420 85 83 0,000 0,06556691 0,06732014 ! phosphoinositide binding GO:0035091 90 83 0,000 0,06556691 0,06730079 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 0,000 0,06633227 0,06806682 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 0,000 0,06633227 0,06804726 GO:0010498|proteasomal protein catabolic process, ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,06633227 0,06802772 ! regulation of membrane potential GO:0042391 92 84 0,000 0,06633227 0,06800819 ! perinuclear region of cytoplasm GO:0048471 91 85 0,000 0,06709705 0,06877255 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,06709705 0,06875281 ! outer membrane GO:0019867 89 85 0,000 0,06709705 0,06873309 ! DNA recombination GO:0006310 86 85 0,000 0,06709705 0,06871338 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,06709705 0,06869368 ! leukocyte differentiation GO:0002521 95 86 0,000 0,06786125 0,06945616 ! Golgi vesicle transport GO:0048193 86 86 0,000 0,06786125 0,06943625 ! pigment granule GO:0048770 90 86 0,000 0,06786125 0,06941636 GO:0042470|melanosome, ! neurotransmitter binding GO:0042165 88 86 0,000 0,06786125 0,06939649 ! anion binding GO:0043168 89 86 0,000 0,06786125 0,06937662 ! sex differentiation GO:0007548 86 86 0,000 0,06786125 0,06935676 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,06786125 0,06933692 ! spindle GO:0005819 89 87 0,000 0,06862488 0,0700971 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,06862488 0,07007705 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 0,000 0,06862488 0,07005702 ! protein processing GO:0016485 92 87 0,000 0,06862488 0,070037 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,06938794 0,07079552 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,06938794 0,0707753 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,06938794 0,07075509 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,06938794 0,07073489 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,06938794 0,07071471 ! detection of stimulus GO:0051606 90 88 0,000 0,06938794 0,07069453 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,07015042 0,07145099 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,07015042 0,07143061 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,07015042 0,07141025 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 0,000 0,07015042 0,0713899 ! regulation of binding GO:0051098 93 90 0,000 0,07091234 0,07214472 ! intermediate filament GO:0005882 92 90 0,000 0,07091234 0,07212417 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,07091234 0,07210363 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,07091234 0,07208311 ! external side of plasma membrane GO:0009897 99 90 0,000 0,07091234 0,07206259 ! growth factor binding GO:0019838 92 90 0,000 0,07091234 0,07204209 ! regulation of nucleotide metabolic process GO:0006140 93 90 0,000 0,07091234 0,0720216 ! adherens junction GO:0005912 96 90 0,000 0,07091234 0,07200112 ! ATP metabolic process GO:0046034 96 91 0,000 0,07167367 0,07275347 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,07167367 0,07273279 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,07167367 0,07271213 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,07167367 0,07269148 ! forebrain development GO:0030900 95 91 0,000 0,07167367 0,07267084 ! carbohydrate biosynthetic process GO:0016051 93 91 0,000 0,07167367 0,07265021 ! apical plasma membrane GO:0016324 96 91 0,000 0,07167367 0,0726296 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,07167367 0,07260899 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,07243444 0,07335887 ! angiogenesis GO:0001525 95 92 0,000 0,07243444 0,07333808 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,07243444 0,07331729 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,07243444 0,07329651 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,07243444 0,07327575 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,07243444 0,073255 ! gland development GO:0048732 95 92 0,000 0,07243444 0,07323426 ! DNA packaging GO:0006323 94 92 0,000 0,07243444 0,07321353 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,07319464 0,07396097 ! receptor complex GO:0043235 97 93 0,000 0,07319464 0,07394004 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,07319464 0,07391913 ! hormone metabolic process GO:0042445 96 93 0,000 0,07319464 0,07389823 ! translational elongation GO:0006414 97 94 0,000 0,07395426 0,07464406 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,07395426 0,07462296 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,07395426 0,07460188 ! protein maturation GO:0051604 99 94 0,000 0,07395426 0,07458082 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,07395426 0,07455976 ! carboxylic acid binding GO:0031406 99 95 0,000 0,07471332 0,07530377 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,07471332 0,07528252 ! response to virus GO:0009615 102 95 0,000 0,07471332 0,07526128 ! peroxisome GO:0005777 97 96 0,000 0,0754718 0,07600389 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,0754718 0,07598246 ! Wnt receptor signaling pathway GO:0016055 104 96 0,000 0,0754718 0,07596105 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,0754718 0,07593964 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,0754718 0,07591825 ! cell fate commitment GO:0045165 98 96 0,000 0,0754718 0,07589687 ! response to nutrient levels GO:0031667 98 96 0,000 0,0754718 0,07587551 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,07622971 0,0766159 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,07622971 0,07659435 ! anchoring junction GO:0070161 103 97 0,000 0,07622971 0,0765728 ! reproductive developmental process GO:0003006 97 97 0,000 0,07622971 0,07655127 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,07622971 0,07652975 ! unfolded protein binding GO:0051082 100 98 0,000 0,07698706 0,07726835 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,07698706 0,07724664 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,07698706 0,07722494 ! chromatin binding GO:0003682 102 99 0,000 0,07774383 0,07796215 ! nuclear chromosome GO:0000228 102 99 0,000 0,07774383 0,07794027 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,07774383 0,07791839 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,07774383 0,07789653 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,07774383 0,07787468 ! electron transport chain GO:0022900 102 100 0,000 0,07850004 0,07861011 ! tRNA metabolic process GO:0006399 101 100 0,000 0,07850004 0,07858807 ! protein polymerization GO:0051258 114 100 0,000 0,07850004 0,07856604 ! cytokine binding GO:0019955 101 100 0,000 0,07850004 0,07854403 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,07850004 0,07852203 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,07850004 0,07850004