pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/387-4-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! actin filament bundle formation GO:0051017 47 20 2,000 1,853E-06 4,527E-03 ! hyperosmotic response GO:0006972 10 6 1,000 2,138E-05 0,02611234 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,984E-05 0,03244541 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 1,000 3,984E-05 0,02433406 ! actin filament organization GO:0007015 167 72 2,000 9,279E-05 0,04533721 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 9,363E-05 0,0381218 ! focal adhesion formation GO:0048041 37 12 1,000 9,363E-05 0,03267583 ! cell-matrix adhesion GO:0007160 181 76 2,000 1,09E-04 0,0332881 ! cell-substrate adhesion GO:0031589 189 82 2,000 1,366E-04 0,0370872 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 1,000 1,486E-04 0,03630517 ! response to osmotic stress GO:0006970 27 16 1,000 1,697E-04 0,03769068 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,697E-04 0,03454979 ! signal complex assembly GO:0007172 47 17 1,000 1,922E-04 0,03611663 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,16E-04 0,0377 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,679E-04 0,04362876 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,679E-04 0,04090196 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,252E-04 0,04673113 ! activation of JUN kinase activity GO:0007257 47 22 1,000 3,252E-04 0,04413496 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 4,561E-04 0,05864604 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,561E-04 0,05571373 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 4,561E-04 0,0530607 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 4,922E-04 0,05465877 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 5,297E-04 0,05626079 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 5,297E-04 0,05391659 ! fat cell differentiation GO:0045444 57 28 1,000 5,297E-04 0,05175993 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 5,297E-04 0,04976916 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,685E-04 0,05143642 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 5,685E-04 0,0495994 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 5,685E-04 0,04788908 ! cell junction assembly GO:0034329 85 31 1,000 6,501E-04 0,0529387 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 6,929E-04 0,05460447 ! spliceosome assembly GO:0000245 75 34 1,000 7,825E-04 0,05973851 ! cell junction organization GO:0034330 96 37 1,000 9,268E-04 0,06861229 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 9,776E-04 0,07024005 ! Rho protein signal transduction GO:0007266 88 40 1,000 1,083E-03 0,07559073 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 1,194E-03 0,08099838 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,43E-03 0,09444567 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 1,43E-03 0,09196026 ! positive regulation of protein transport GO:0051222 80 46 1,000 1,43E-03 0,0896023 ! regulation of JNK cascade GO:0046328 104 47 1,000 1,493E-03 0,09117507 ! response to insulin stimulus GO:0032868 98 47 1,000 1,493E-03 0,08895129 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,557E-03 0,09053932 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 1,557E-03 0,08843376 ! response to calcium ion GO:0051592 94 49 1,000 1,622E-03 0,09003246 ! JNK cascade GO:0007254 106 49 1,000 1,622E-03 0,08803174 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 1,755E-03 0,0932247 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 1,824E-03 0,09481814 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 1,894E-03 0,09640973 ! response to UV GO:0009411 120 55 1,000 2,038E-03 0,10161964 ! negative regulation of cell motion GO:0051271 142 55 1,000 2,038E-03 0,09958724 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,187E-03 0,10477181 ! regulation of intracellular transport GO:0032386 108 57 1,000 2,187E-03 0,10275697 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 2,748E-03 0,12666827 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 2,748E-03 0,12432256 ! activation of MAPK activity GO:0000187 124 67 1,000 3,007E-03 0,13356162 ! regulation of cellular response to stress GO:0080135 142 68 1,000 3,096E-03 0,13504821 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 3,096E-03 0,13267894 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 3,186E-03 0,1341809 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 3,463E-03 0,14338455 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 3,463E-03 0,14099481 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 3,463E-03 0,13868341 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,654E-03 0,1439666 ! positive regulation of ligase activity GO:0051351 130 77 1,000 3,949E-03 0,15313195 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 4,152E-03 0,15848179 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 4,359E-03 0,16384568 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 4,572E-03 0,16922213 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 4,68E-03 0,17063168 ! regulation of ligase activity GO:0051340 147 84 1,000 4,68E-03 0,16812239 ! regulation of neuron differentiation GO:0045664 187 85 1,000 4,789E-03 0,16954859 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 4,789E-03 0,16712647 ! regulation of protein transport GO:0051223 165 87 1,000 5,01E-03 0,17240125 GO:0070201|regulation of establishment of protein localization, ! response to inorganic substance GO:0010035 173 90 1,000 5,352E-03 0,18158722 ! positive regulation of protein modification process GO:0031401 156 90 1,000 5,352E-03 0,17909973 ! response to unfolded protein GO:0006986 139 90 1,000 5,352E-03 0,17667946 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 5,703E-03 0,18578011 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 5,703E-03 0,18333564 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,035E-03 0,19146019 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,035E-03 0,18900557 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,035E-03 0,1866131 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,035E-03 0,18428043 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,035E-03 0,18200537 ! neuron fate determination GO:0048664 7 5 0,000 6,035E-03 0,17978579 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,035E-03 0,1776197 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,035E-03 0,17550518 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,035E-03 0,17344041 ! polyol transport GO:0015791 12 5 0,000 6,035E-03 0,17142366 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,035E-03 0,16945327 ! response to superoxide GO:0000303 10 5 0,000 6,035E-03 0,16752767 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,035E-03 0,16564533 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,035E-03 0,16380483 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,035E-03 0,16200478 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,035E-03 0,16024386 ! female meiosis GO:0007143 10 5 0,000 6,035E-03 0,1585208 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,035E-03 0,15683441 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,035E-03 0,15518352 ! hypothalamus development GO:0021854 9 5 0,000 6,035E-03 0,15356703 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,035E-03 0,15198386 ! cobalt ion transport GO:0006824 11 5 0,000 6,035E-03 0,15043301 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,035E-03 0,14891348 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,035E-03 0,14742435 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,035E-03 0,1459647 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,035E-03 0,14453367 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,035E-03 0,14313043 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,035E-03 0,14175418 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,035E-03 0,14040414 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,035E-03 0,13907957 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,035E-03 0,13777976 ! transposition GO:0032196 9 5 0,000 6,035E-03 0,13650403 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,035E-03 0,1352517 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,035E-03 0,13402213 ! negative chemotaxis GO:0050919 16 5 0,000 6,035E-03 0,13281473 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,035E-03 0,13162888 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,035E-03 0,13046402 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,035E-03 0,1293196 ! behavioral response to pain GO:0048266 10 5 0,000 6,035E-03 0,12819508 ! clathrin coat assembly GO:0048268 15 5 0,000 6,035E-03 0,12708995 ! Notch receptor processing GO:0007220 11 5 0,000 6,035E-03 0,12600372 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,035E-03 0,12493589 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,035E-03 0,12388601 ! micturition GO:0060073 9 5 0,000 6,035E-03 0,12285362 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,035E-03 0,1218383 ! copulation GO:0007620 9 5 0,000 6,035E-03 0,12083963 ! glial cell fate commitment GO:0021781 14 5 0,000 6,035E-03 0,11985719 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,035E-03 0,1188906 ! bioluminescence GO:0008218 9 5 0,000 6,035E-03 0,11793948 ! spermidine metabolic process GO:0008216 7 5 0,000 6,035E-03 0,11700345 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,035E-03 0,11608216 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,035E-03 0,11517527 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,035E-03 0,11428244 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,035E-03 0,11340334 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,035E-03 0,11253767 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,035E-03 0,11168511 ! grooming behavior GO:0007625 6 5 0,000 6,035E-03 0,11084537 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,035E-03 0,11001817 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,035E-03 0,10920322 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,035E-03 0,10840026 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,035E-03 0,10760901 ! response to protozoan GO:0001562 13 5 0,000 6,035E-03 0,10682924 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,035E-03 0,10606068 ! lymph vessel development GO:0001945 10 5 0,000 6,035E-03 0,10530311 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,035E-03 0,10455627 ! endochondral ossification GO:0001958 17 5 0,000 6,035E-03 0,10381996 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,035E-03 0,10309395 ! single strand break repair GO:0000012 8 5 0,000 6,035E-03 0,10237802 ! parathyroid gland development GO:0060017 14 5 0,000 6,035E-03 0,10167196 ! anagen GO:0042640 7 5 0,000 6,035E-03 0,10097558 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,035E-03 0,10028867 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,035E-03 0,09961105 ! cytokine secretion GO:0050663 15 5 0,000 6,035E-03 0,09894252 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,035E-03 0,0982829 ! ceramide catabolic process GO:0046514 7 5 0,000 6,035E-03 0,09763202 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,035E-03 0,0969897 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,035E-03 0,09635578 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,035E-03 0,0957301 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,035E-03 0,09511248 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,035E-03 0,09450279 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,035E-03 0,09390086 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,035E-03 0,09330655 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,035E-03 0,09271972 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,035E-03 0,09214022 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,035E-03 0,09156792 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,035E-03 0,09100268 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,035E-03 0,09044439 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,035E-03 0,08989289 ! microvillus organization GO:0032528 8 5 0,000 6,035E-03 0,08934809 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,035E-03 0,08880985 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,035E-03 0,08827805 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,035E-03 0,08775259 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,035E-03 0,08723334 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,035E-03 0,0867202 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,035E-03 0,08621307 ! polyol catabolic process GO:0046174 9 5 0,000 6,035E-03 0,08571183 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,035E-03 0,08521639 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,035E-03 0,08472664 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,035E-03 0,08424248 ! muscle cell migration GO:0014812 8 5 0,000 6,035E-03 0,08376383 ! mitochondrial fission GO:0000266 8 5 0,000 6,035E-03 0,08329059 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,035E-03 0,08282267 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,035E-03 0,08235997 ! mRNA transcription GO:0009299 10 5 0,000 6,035E-03 0,08190242 ! nerve growth factor processing GO:0032455 9 5 0,000 6,035E-03 0,08144992 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,035E-03 0,08100239 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,035E-03 0,08055975 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,035E-03 0,08012193 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,035E-03 0,07968884 ! monocyte activation GO:0042117 10 5 0,000 6,035E-03 0,0792604 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,035E-03 0,07883655 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,035E-03 0,07841721 ! response to food GO:0032094 6 5 0,000 6,035E-03 0,0780023 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,035E-03 0,07759176 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,035E-03 0,07718552 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,035E-03 0,07678351 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,035E-03 0,07638567 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,035E-03 0,07599193 ! forebrain neuron development GO:0021884 13 5 0,000 6,035E-03 0,07560223 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,035E-03 0,0752165 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,035E-03 0,07483469 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,035E-03 0,07445674 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,035E-03 0,07408259 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,035E-03 0,07371217 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,035E-03 0,07334545 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,035E-03 0,07298235 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,035E-03 0,07262283 ! lipid glycosylation GO:0030259 7 5 0,000 6,035E-03 0,07226684 ! nucleobase transport GO:0015851 6 5 0,000 6,035E-03 0,07191432 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,035E-03 0,07156522 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,035E-03 0,07121949 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,035E-03 0,07087709 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,035E-03 0,07053797 ! basic amino acid transport GO:0015802 12 5 0,000 6,035E-03 0,07020207 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,035E-03 0,06986936 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,035E-03 0,06953979 ! actin nucleation GO:0045010 11 5 0,000 6,035E-03 0,06921331 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,035E-03 0,06888988 ! depurination GO:0045007 5 5 0,000 6,035E-03 0,06856946 ! depyrimidination GO:0045008 10 5 0,000 6,035E-03 0,06825201 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,035E-03 0,06793749 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,035E-03 0,06762585 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,035E-03 0,06731705 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,035E-03 0,06701107 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,035E-03 0,06670785 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,035E-03 0,06640736 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,035E-03 0,06610957 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,035E-03 0,06581444 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,035E-03 0,06552193 ! activated T cell proliferation GO:0050798 16 5 0,000 6,035E-03 0,06523201 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,035E-03 0,06494465 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,035E-03 0,0646598 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,035E-03 0,06437744 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,035E-03 0,06409754 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,035E-03 0,06382006 ! response to arsenic GO:0046685 11 5 0,000 6,035E-03 0,06354498 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,035E-03 0,06327225 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,035E-03 0,06300186 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,035E-03 0,06273376 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,035E-03 0,06246794 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,035E-03 0,06220437 ! response to mercury ion GO:0046689 8 5 0,000 6,035E-03 0,061943 ! response to cadmium ion GO:0046686 7 5 0,000 6,035E-03 0,06168383 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,035E-03 0,06142681 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,035E-03 0,06117193 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 6,035E-03 0,06091915 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,035E-03 0,06066846 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,035E-03 0,06041981 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,035E-03 0,0601732 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,035E-03 0,0599286 ! decidualization GO:0046697 11 5 0,000 6,035E-03 0,05968597 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,035E-03 0,0594453 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,035E-03 0,05920657 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,035E-03 0,05896974 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,035E-03 0,0587348 ! embryonic cleavage GO:0040016 6 5 0,000 6,035E-03 0,05850173 ! peroxisome fission GO:0016559 5 5 0,000 6,035E-03 0,05827049 ! histone demethylation GO:0016577 13 5 0,000 6,035E-03 0,05804108 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,035E-03 0,05781347 ! mitotic recombination GO:0006312 9 5 0,000 6,035E-03 0,05758764 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,035E-03 0,05736356 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,035E-03 0,05714122 ! metaphase plate congression GO:0051310 7 5 0,000 6,035E-03 0,0569206 ! regulation of sterol transport GO:0032371 7 5 0,000 6,035E-03 0,05670167 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,035E-03 0,05648442 ! enteric nervous system development GO:0048484 8 5 0,000 6,035E-03 0,05626884 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,035E-03 0,05605489 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,035E-03 0,05584256 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,035E-03 0,05563183 ! muscle cell proliferation GO:0033002 12 5 0,000 6,035E-03 0,05542269 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,035E-03 0,05521511 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,035E-03 0,05500908 ! B cell homeostasis GO:0001782 13 5 0,000 6,035E-03 0,05480459 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,035E-03 0,05460161 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,035E-03 0,05440013 ! metaphase GO:0051323 11 5 0,000 6,035E-03 0,05420013 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,035E-03 0,05400159 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,035E-03 0,05380451 ! cellular response to nutrient GO:0031670 8 5 0,000 6,035E-03 0,05360885 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,035E-03 0,05341462 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,035E-03 0,05322179 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,035E-03 0,05303034 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,035E-03 0,05284027 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,035E-03 0,05265155 ! response to redox state GO:0051775 6 5 0,000 6,035E-03 0,05246418 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,035E-03 0,05227814 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,035E-03 0,05209341 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,035E-03 0,05190998 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,035E-03 0,05172784 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,035E-03 0,05154697 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,035E-03 0,05136737 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,035E-03 0,05118901 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,035E-03 0,05101189 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,035E-03 0,05083598 ! striatum development GO:0021756 14 5 0,000 6,035E-03 0,05066129 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,035E-03 0,05048779 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,035E-03 0,05031548 ! glial cell migration GO:0008347 10 5 0,000 6,035E-03 0,05014434 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,035E-03 0,04997436 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,035E-03 0,04980552 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,035E-03 0,04963783 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,035E-03 0,04947126 ! T cell activation during immune response GO:0002286 9 5 0,000 6,035E-03 0,0493058 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,035E-03 0,04914145 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,035E-03 0,04897819 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,035E-03 0,04881601 ! neuroprotection GO:0043526 8 5 0,000 6,035E-03 0,0486549 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,035E-03 0,04849485 ! regulation of sensory perception GO:0051931 8 5 0,000 6,035E-03 0,04833585 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,035E-03 0,04817789 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,035E-03 0,04802096 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,035E-03 0,04786505 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,035E-03 0,04771014 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,035E-03 0,04755624 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,035E-03 0,04740333 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,035E-03 0,04725139 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,035E-03 0,04710043 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,035E-03 0,04695043 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,035E-03 0,04680138 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,035E-03 0,04665327 ! spindle assembly GO:0051225 6 5 0,000 6,035E-03 0,0465061 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,035E-03 0,04635986 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,035E-03 0,04621453 ! protein palmitoylation GO:0018345 12 5 0,000 6,035E-03 0,04607011 ! drug metabolic process GO:0017144 7 5 0,000 6,035E-03 0,04592659 ! stem cell division GO:0017145 11 5 0,000 6,035E-03 0,04578396 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,035E-03 0,04564221 ! organ regeneration GO:0031100 7 5 0,000 6,035E-03 0,04550134 ! carnitine metabolic process GO:0009437 8 5 0,000 6,035E-03 0,04536134 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,035E-03 0,04522219 ! response to protein stimulus GO:0051789 158 96 1,000 6,065E-03 0,04531495 ! regulation of protein localization GO:0032880 188 97 1,000 6,188E-03 0,04609266 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 6,313E-03 0,04687409 ! skeletal muscle tissue development GO:0007519 223 100 1,000 6,564E-03 0,0485947 GO:0060538|skeletal muscle organ development, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,237E-03 0,05341534 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,237E-03 0,05325445 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,237E-03 0,05309452 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,237E-03 0,05293556 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,237E-03 0,05277754 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,237E-03 0,05262047 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,237E-03 0,05246432 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,237E-03 0,0523091 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,237E-03 0,0521548 ! response to oxygen radical GO:0000305 11 6 0,000 7,237E-03 0,0520014 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,237E-03 0,05184891 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,237E-03 0,0516973 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,237E-03 0,05154658 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,237E-03 0,05139673 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,237E-03 0,05124776 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,237E-03 0,05109964 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,237E-03 0,05095238 ! forebrain regionalization GO:0021871 9 6 0,000 7,237E-03 0,05080597 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,237E-03 0,05066039 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,237E-03 0,05051565 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,237E-03 0,05037173 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,237E-03 0,05022863 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,237E-03 0,05008634 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,237E-03 0,04994485 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,237E-03 0,04980416 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,237E-03 0,04966426 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,237E-03 0,04952515 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,237E-03 0,04938681 ! malate metabolic process GO:0006108 13 6 0,000 7,237E-03 0,04924924 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,237E-03 0,04911244 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,237E-03 0,04897639 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,237E-03 0,0488411 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,237E-03 0,04870655 ! protein refolding GO:0042026 15 6 0,000 7,237E-03 0,04857274 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,237E-03 0,04843966 ! opsonization GO:0008228 8 6 0,000 7,237E-03 0,04830731 ! mating behavior GO:0007617 7 6 0,000 7,237E-03 0,04817569 ! erythrocyte maturation GO:0043249 8 6 0,000 7,237E-03 0,04804477 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,237E-03 0,04791457 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,237E-03 0,04778507 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 7,237E-03 0,04765627 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,237E-03 0,04752816 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,237E-03 0,04740074 ! response to interferon-gamma GO:0034341 16 6 0,000 7,237E-03 0,047274 ! toxin metabolic process GO:0009404 11 6 0,000 7,237E-03 0,04714794 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,237E-03 0,04702254 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,237E-03 0,04689782 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,237E-03 0,04677375 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 7,237E-03 0,04665033 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 7,237E-03 0,04652757 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,237E-03 0,04640545 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,237E-03 0,04628397 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,237E-03 0,04616312 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,237E-03 0,04604291 ! thymic T cell selection GO:0045061 16 6 0,000 7,237E-03 0,04592332 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,237E-03 0,04580434 ! protein lipoylation GO:0009249 10 6 0,000 7,237E-03 0,04568599 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,237E-03 0,04556824 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,237E-03 0,0454511 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,237E-03 0,04533456 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,237E-03 0,04521861 ! glutamate catabolic process GO:0006538 12 6 0,000 7,237E-03 0,04510326 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 7,237E-03 0,04498849 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,237E-03 0,04487431 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,237E-03 0,0447607 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,237E-03 0,04464767 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,237E-03 0,04453521 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,237E-03 0,04442331 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,237E-03 0,04431197 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,237E-03 0,04420119 ! urea metabolic process GO:0019627 7 6 0,000 7,237E-03 0,04409096 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,237E-03 0,04398129 ! neutrophil activation GO:0042119 7 6 0,000 7,237E-03 0,04387215 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,237E-03 0,04376356 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,237E-03 0,0436555 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,237E-03 0,04354797 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,237E-03 0,04344097 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,237E-03 0,0433345 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,237E-03 0,04322855 ! neuron apoptosis GO:0051402 15 6 0,000 7,237E-03 0,04312311 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,237E-03 0,04301819 ! T cell mediated immunity GO:0002456 17 6 0,000 7,237E-03 0,04291378 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,237E-03 0,04280987 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 7,237E-03 0,04270647 ! carnitine transport GO:0015879 10 6 0,000 7,237E-03 0,04260356 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,237E-03 0,04250115 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,237E-03 0,04239922 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,237E-03 0,04229779 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,237E-03 0,04219684 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,237E-03 0,04209637 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,237E-03 0,04199638 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,237E-03 0,04189686 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,237E-03 0,04179782 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,237E-03 0,04169924 ! establishment of spindle localization GO:0051293 16 6 0,000 7,237E-03 0,04160112 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,237E-03 0,04150347 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,237E-03 0,04140627 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,237E-03 0,04130953 ! response to UV-C GO:0010225 14 6 0,000 7,237E-03 0,04121323 ! astrocyte development GO:0014002 16 6 0,000 7,237E-03 0,04111739 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,237E-03 0,04102199 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,237E-03 0,04092703 ! interaction with symbiont GO:0051702 14 6 0,000 7,237E-03 0,04083251 ! regulation of dendrite development GO:0050773 16 6 0,000 7,237E-03 0,04073843 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,237E-03 0,04064477 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,237E-03 0,04055155 ! response to copper ion GO:0046688 10 6 0,000 7,237E-03 0,04045876 ! response to exogenous dsRNA GO:0043330 13 6 0,000 7,237E-03 0,04036639 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,237E-03 0,04027443 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,237E-03 0,0401829 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,237E-03 0,04009178 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,237E-03 0,04000108 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,237E-03 0,03991078 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,237E-03 0,03982089 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,237E-03 0,03973141 ! hair follicle maturation GO:0048820 8 6 0,000 7,237E-03 0,03964232 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,237E-03 0,03955364 ! Schwann cell development GO:0014044 15 6 0,000 7,237E-03 0,03946535 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,237E-03 0,03937745 ! response to pheromone GO:0019236 6 6 0,000 7,237E-03 0,03928995 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,237E-03 0,03920283 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,237E-03 0,0391161 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,237E-03 0,03902975 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,237E-03 0,03894378 ! subpallium development GO:0021544 15 6 0,000 7,237E-03 0,03885819 ! neural tube patterning GO:0021532 8 6 0,000 7,237E-03 0,03877298 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,237E-03 0,03868813 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,237E-03 0,03860366 ! maintenance of organ identity GO:0048496 9 6 0,000 7,237E-03 0,03851956 ! G2 phase GO:0051319 16 6 0,000 7,237E-03 0,03843582 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,237E-03 0,03835244 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,237E-03 0,03826943 ! oxygen homeostasis GO:0032364 10 6 0,000 7,237E-03 0,03818677 ! establishment of planar polarity GO:0001736 7 6 0,000 7,237E-03 0,03810448 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,237E-03 0,03802253 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,237E-03 0,03794094 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,237E-03 0,03785969 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,237E-03 0,0377788 ! receptor internalization GO:0031623 11 6 0,000 7,237E-03 0,03769824 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,237E-03 0,03761804 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 7,237E-03 0,03753817 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,237E-03 0,03745864 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,237E-03 0,03737944 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,237E-03 0,03730058 ! protein deubiquitination GO:0016579 16 6 0,000 7,237E-03 0,03722206 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,237E-03 0,03714386 ! protein destabilization GO:0031648 9 6 0,000 7,237E-03 0,03706599 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,237E-03 0,03698845 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,237E-03 0,03691123 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,237E-03 0,03683433 ! regulation of viral transcription GO:0046782 11 6 0,000 7,237E-03 0,03675775 ! progesterone metabolic process GO:0042448 12 6 0,000 7,237E-03 0,03668149 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,237E-03 0,03660554 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,237E-03 0,03652991 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,237E-03 0,03645459 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,237E-03 0,03637958 ! determination of adult lifespan GO:0008340 17 6 0,000 7,237E-03 0,03630488 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,237E-03 0,03623049 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,237E-03 0,03615639 ! neural plate development GO:0001840 9 6 0,000 7,237E-03 0,03608261 ! catecholamine transport GO:0051937 9 6 0,000 7,237E-03 0,03600912 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,237E-03 0,03593593 ! sensory cilium assembly GO:0035058 10 6 0,000 7,237E-03 0,03586304 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,237E-03 0,03579044 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,237E-03 0,03571813 ! maternal placenta development GO:0001893 12 6 0,000 7,237E-03 0,03564612 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,237E-03 0,0355744 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,237E-03 0,03550297 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,237E-03 0,03543182 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,237E-03 0,03536095 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,237E-03 0,03529037 ! positive regulation of coagulation GO:0050820 13 6 0,000 7,237E-03 0,03522007 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,237E-03 0,03515005 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 8,438E-03 0,04090287 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 8,438E-03 0,04082187 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 8,438E-03 0,0407412 ! behavioral response to cocaine GO:0048148 14 7 0,000 8,438E-03 0,04066084 ! regulation of helicase activity GO:0051095 16 7 0,000 8,438E-03 0,0405808 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 8,438E-03 0,04050107 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 8,438E-03 0,04042166 ! sleep GO:0030431 16 7 0,000 8,438E-03 0,04034256 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,438E-03 0,04026376 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 8,438E-03 0,04018528 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,438E-03 0,04010709 ! prostate gland development GO:0030850 14 7 0,000 8,438E-03 0,04002922 ! nucleotide-sugar transport GO:0015780 11 7 0,000 8,438E-03 0,03995164 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,438E-03 0,03987436 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,438E-03 0,03979739 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 8,438E-03 0,03972071 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,438E-03 0,03964432 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 8,438E-03 0,03956823 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 8,438E-03 0,03949243 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,438E-03 0,03941691 ! SMAD protein complex assembly GO:0007183 13 7 0,000 8,438E-03 0,03934169 ! glycolipid transport GO:0046836 11 7 0,000 8,438E-03 0,03926676 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,438E-03 0,0391921 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,438E-03 0,03911774 ! neuron adhesion GO:0007158 14 7 0,000 8,438E-03 0,03904365 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 8,438E-03 0,03896984 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,438E-03 0,03889631 ! establishment of tissue polarity GO:0007164 8 7 0,000 8,438E-03 0,03882306 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 8,438E-03 0,03875009 ! mRNA stabilization GO:0048255 18 7 0,000 8,438E-03 0,03867739 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 8,438E-03 0,03860496 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 8,438E-03 0,0385328 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 8,438E-03 0,03846091 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 8,438E-03 0,03838929 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,438E-03 0,03831793 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,438E-03 0,03824684 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,438E-03 0,03817601 ! lipoprotein transport GO:0042953 14 7 0,000 8,438E-03 0,03810545 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,438E-03 0,03803514 ! rhythmic behavior GO:0007622 17 7 0,000 8,438E-03 0,03796509 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 8,438E-03 0,03789531 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 8,438E-03 0,03782577 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 8,438E-03 0,0377565 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 8,438E-03 0,03768747 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,438E-03 0,0376187 ! regulation of odontogenesis GO:0042481 14 7 0,000 8,438E-03 0,03755018 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,438E-03 0,0374819 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 8,438E-03 0,03741388 ! mechanosensory behavior GO:0007638 16 7 0,000 8,438E-03 0,0373461 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 8,438E-03 0,03727857 ! positive regulation of isotype switching GO:0045830 17 7 0,000 8,438E-03 0,03721128 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 8,438E-03 0,03714423 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 8,438E-03 0,03707742 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,438E-03 0,03701086 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,438E-03 0,03694453 ! spinal cord patterning GO:0021511 14 7 0,000 8,438E-03 0,03687844 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 8,438E-03 0,03681258 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 8,438E-03 0,03674696 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,438E-03 0,03668158 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 8,438E-03 0,03661642 ! adrenal gland development GO:0030325 17 7 0,000 8,438E-03 0,0365515 ! cysteine metabolic process GO:0006534 13 7 0,000 8,438E-03 0,03648681 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 8,438E-03 0,03642234 ! ovulation GO:0030728 10 7 0,000 8,438E-03 0,03635811 ! adenohypophysis development GO:0021984 11 7 0,000 8,438E-03 0,0362941 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 8,438E-03 0,03623031 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 8,438E-03 0,03616675 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 8,438E-03 0,03610341 ! microtubule nucleation GO:0007020 21 7 0,000 8,438E-03 0,03604029 ! proline biosynthetic process GO:0006561 10 7 0,000 8,438E-03 0,03597739 ! tryptophan metabolic process GO:0006568 11 7 0,000 8,438E-03 0,03591472 ! thyroid hormone generation GO:0006590 13 7 0,000 8,438E-03 0,03585225 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 8,438E-03 0,03579001 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 8,438E-03 0,03572798 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,438E-03 0,03566617 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 8,438E-03 0,03560457 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 8,438E-03 0,03554318 ! galactose metabolic process GO:0006012 13 7 0,000 8,438E-03 0,03548201 ! vesicle fusion GO:0006906 20 7 0,000 8,438E-03 0,03542104 ! response to dietary excess GO:0002021 8 7 0,000 8,438E-03 0,03536029 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,438E-03 0,03529974 ! intracellular pH reduction GO:0051452 13 7 0,000 8,438E-03 0,0352394 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,438E-03 0,03517926 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 8,438E-03 0,03511933 ! organ growth GO:0035265 15 7 0,000 8,438E-03 0,0350596 ! nucleoside transport GO:0015858 11 7 0,000 8,438E-03 0,03500008 ! nucleoside salvage GO:0043174 11 7 0,000 8,438E-03 0,03494076 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 8,438E-03 0,03488164 ! male sex determination GO:0030238 15 7 0,000 8,438E-03 0,03482271 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 8,438E-03 0,03476399 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 8,438E-03 0,03470547 ! parturition GO:0007567 16 7 0,000 8,438E-03 0,03464714 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 8,438E-03 0,034589 ! rRNA modification GO:0000154 14 7 0,000 8,438E-03 0,03453107 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 8,438E-03 0,03447332 ! spindle checkpoint GO:0031577 16 7 0,000 8,438E-03 0,03441577 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 8,438E-03 0,03435841 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 8,438E-03 0,03430124 ! monocyte differentiation GO:0030224 16 7 0,000 8,438E-03 0,03424426 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 8,438E-03 0,03418747 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,438E-03 0,03413087 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 8,438E-03 0,03407446 ! hyaluronan metabolic process GO:0030212 9 7 0,000 8,438E-03 0,03401823 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 8,438E-03 0,03396219 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,438E-03 0,03390633 ! fibrinolysis GO:0042730 11 7 0,000 8,438E-03 0,03385065 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 8,438E-03 0,03379516 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,438E-03 0,03373985 ! eating behavior GO:0042755 8 7 0,000 8,438E-03 0,03368472 ! B cell lineage commitment GO:0002326 21 7 0,000 8,438E-03 0,03362977 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,438E-03 0,03357499 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 8,438E-03 0,0335204 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 8,438E-03 0,03346598 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,438E-03 0,03341174 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 8,438E-03 0,03335768 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,438E-03 0,03330379 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 8,438E-03 0,03325008 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 8,438E-03 0,03319653 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 8,438E-03 0,03314316 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 8,438E-03 0,03308996 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,438E-03 0,03303693 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 8,438E-03 0,03298407 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,438E-03 0,03293138 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,438E-03 0,03287886 ! histone ubiquitination GO:0016574 9 7 0,000 8,438E-03 0,03282651 ! regulation of meiosis GO:0040020 12 7 0,000 8,438E-03 0,03277432 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 8,438E-03 0,0327223 ! T cell lineage commitment GO:0002360 16 7 0,000 8,438E-03 0,03267044 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 8,438E-03 0,03261874 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,438E-03 0,03256721 ! membrane to membrane docking GO:0022614 14 7 0,000 8,438E-03 0,03251585 ! transcription termination GO:0006353 14 7 0,000 8,438E-03 0,03246464 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,438E-03 0,0324136 ! anaphase GO:0051322 18 7 0,000 8,438E-03 0,03236271 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 8,438E-03 0,03231199 ! axonal fasciculation GO:0007413 19 7 0,000 8,438E-03 0,03226142 ! negative regulation of nuclear division GO:0051784 15 7 0,000 8,438E-03 0,03221101 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 8,438E-03 0,03216076 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 8,438E-03 0,03211066 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 8,438E-03 0,03206073 ! diuresis GO:0030146 12 7 0,000 8,438E-03 0,03201094 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,438E-03 0,03196131 ! thiamin metabolic process GO:0006772 7 7 0,000 8,438E-03 0,03191184 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,438E-03 0,03186251 ! antibiotic transport GO:0042891 9 7 0,000 8,438E-03 0,03181334 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,438E-03 0,03176432 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 8,438E-03 0,03171546 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 8,438E-03 0,03166674 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 8,438E-03 0,03161817 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 8,438E-03 0,03156975 ! melanin biosynthetic process GO:0042438 10 7 0,000 8,438E-03 0,03152148 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 8,438E-03 0,03147335 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,438E-03 0,03142538 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,438E-03 0,03137754 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 8,438E-03 0,03132986 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 8,438E-03 0,03128232 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 8,438E-03 0,03123492 ! endosome to lysosome transport GO:0008333 12 7 0,000 8,438E-03 0,03118766 ! protein modification by small protein removal GO:0070646 19 7 0,000 8,438E-03 0,03114055 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 8,438E-03 0,03109358 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 8,438E-03 0,03104676 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 8,438E-03 0,03100007 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 8,438E-03 0,03095352 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,438E-03 0,03090712 ! muscle adaptation GO:0043500 13 7 0,000 8,438E-03 0,03086085 ! embryonic heart tube development GO:0035050 14 7 0,000 8,438E-03 0,03081472 ! retina homeostasis GO:0001895 12 7 0,000 8,438E-03 0,03076873 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 8,438E-03 0,03072287 ! protein amino acid prenylation GO:0018346 19 7 0,000 8,438E-03 0,03067715 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 8,438E-03 0,03063157 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 8,438E-03 0,03058612 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 9,638E-03 0,03488318 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 9,638E-03 0,03483158 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 9,638E-03 0,03478013 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 9,638E-03 0,03472883 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 9,638E-03 0,03467768 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,638E-03 0,03462669 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,638E-03 0,03457584 ! male meiosis GO:0007140 9 8 0,000 9,638E-03 0,03452514 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 9,638E-03 0,03447459 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 9,638E-03 0,03442419 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 9,638E-03 0,03437394 ! meiotic prophase I GO:0007128 14 8 0,000 9,638E-03 0,03432383 ! response to zinc ion GO:0010043 12 8 0,000 9,638E-03 0,03427387 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 9,638E-03 0,03422405 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,638E-03 0,03417438 ! oligopeptide transport GO:0006857 16 8 0,000 9,638E-03 0,03412485 ! actin-myosin filament sliding GO:0033275 13 8 0,000 9,638E-03 0,03407547 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 9,638E-03 0,03402623 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 9,638E-03 0,03397713 ! signal peptide processing GO:0006465 12 8 0,000 9,638E-03 0,03392817 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 9,638E-03 0,03387935 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 9,638E-03 0,03383067 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,638E-03 0,03378213 ! succinate metabolic process GO:0006105 17 8 0,000 9,638E-03 0,03373374 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 9,638E-03 0,03368548 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,638E-03 0,03363735 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,638E-03 0,03358937 ! estrogen metabolic process GO:0008210 17 8 0,000 9,638E-03 0,03354152 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 9,638E-03 0,03349381 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,638E-03 0,03344623 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 9,638E-03 0,03339879 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,638E-03 0,03335148 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,638E-03 0,03330431 ! reflex GO:0060004 17 8 0,000 9,638E-03 0,03325727 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,638E-03 0,03321036 ! glycerolipid catabolic process GO:0046503 14 8 0,000 9,638E-03 0,03316359 ! hemoglobin metabolic process GO:0020027 14 8 0,000 9,638E-03 0,03311695 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,638E-03 0,03307043 ! pigment granule organization GO:0048753 17 8 0,000 9,638E-03 0,03302405 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,638E-03 0,0329778 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 9,638E-03 0,03293168 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 9,638E-03 0,03288568 ! astrocyte differentiation GO:0048708 19 8 0,000 9,638E-03 0,03283982 ! histidine catabolic process GO:0006548 10 8 0,000 9,638E-03 0,03279408 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,638E-03 0,03274847 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 9,638E-03 0,03270298 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 9,638E-03 0,03265763 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 9,638E-03 0,03261239 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 9,638E-03 0,03256729 ! regulation of pigmentation during development GO:0048070 25 8 0,000 9,638E-03 0,0325223 ! melanin metabolic process GO:0006582 17 8 0,000 9,638E-03 0,03247745 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 9,638E-03 0,03243271 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 9,638E-03 0,0323881 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 9,638E-03 0,03234361 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,638E-03 0,03229924 ! macrophage activation GO:0042116 13 8 0,000 9,638E-03 0,032255 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,638E-03 0,03221087 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,638E-03 0,03216687 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 9,638E-03 0,03212298 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,638E-03 0,03207922 ! purine salvage GO:0043101 12 8 0,000 9,638E-03 0,03203558 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 9,638E-03 0,03199205 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,638E-03 0,03194864 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 9,638E-03 0,03190535 ! osteoblast development GO:0002076 17 8 0,000 9,638E-03 0,03186218 ! positive regulation of vasodilation GO:0045909 14 8 0,000 9,638E-03 0,03181912 ! negative regulation of translational initiation GO:0045947 12 8 0,000 9,638E-03 0,03177618 ! Schwann cell differentiation GO:0014037 21 8 0,000 9,638E-03 0,03173335 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 9,638E-03 0,03169064 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,638E-03 0,03164805 ! response to UV-B GO:0010224 17 8 0,000 9,638E-03 0,03160557 ! protein targeting to vacuole GO:0006623 14 8 0,000 9,638E-03 0,0315632 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,638E-03 0,03152095 ! intermediate filament organization GO:0045109 12 8 0,000 9,638E-03 0,03147881 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 9,638E-03 0,03143678 ! cellular extravasation GO:0045123 13 8 0,000 9,638E-03 0,03139486 ! cardiac muscle cell development GO:0055013 14 8 0,000 9,638E-03 0,03135306 ! response to antibiotic GO:0046677 11 8 0,000 9,638E-03 0,03131137 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 9,638E-03 0,03126978 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 9,638E-03 0,03122831 ! DNA topological change GO:0006265 12 8 0,000 9,638E-03 0,03118695 ! response to tropane GO:0014073 15 8 0,000 9,638E-03 0,0311457 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 9,638E-03 0,03110455 ! melanosome transport GO:0032402 13 8 0,000 9,638E-03 0,03106352 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 9,638E-03 0,03102259 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 9,638E-03 0,03098177 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,638E-03 0,03094106 ! mast cell activation GO:0045576 14 8 0,000 9,638E-03 0,03090046 ! multicellular organismal aging GO:0010259 20 8 0,000 9,638E-03 0,03085996 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 9,638E-03 0,03081957 ! gas homeostasis GO:0033483 14 8 0,000 9,638E-03 0,03077928 ! dendrite morphogenesis GO:0048813 14 8 0,000 9,638E-03 0,0307391 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 9,638E-03 0,03069902 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 9,638E-03 0,03065905 ! nucleosome disassembly GO:0006337 14 8 0,000 9,638E-03 0,03061918 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,638E-03 0,03057941 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 9,638E-03 0,03053975 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,638E-03 0,03050019 ! establishment of chromosome localization GO:0051303 14 8 0,000 9,638E-03 0,03046073 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 9,638E-03 0,03042138 ! intracellular lipid transport GO:0032365 16 8 0,000 9,638E-03 0,03038213 ! response to tumor cell GO:0002347 16 8 0,000 9,638E-03 0,03034297 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,638E-03 0,03030392 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 9,638E-03 0,03026497 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 9,638E-03 0,03022612 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 9,638E-03 0,03018737 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,638E-03 0,03014872 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 9,638E-03 0,03011016 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 9,638E-03 0,03007171 ! hormone catabolic process GO:0042447 17 8 0,000 9,638E-03 0,03003335 ! glycolipid catabolic process GO:0019377 16 8 0,000 9,638E-03 0,02999509 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 9,638E-03 0,02995693 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 9,638E-03 0,02991887 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 9,638E-03 0,0298809 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,638E-03 0,02984303 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 9,638E-03 0,02980525 ! adult feeding behavior GO:0008343 10 8 0,000 9,638E-03 0,02976757 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 9,638E-03 0,02972998 ! ATP catabolic process GO:0006200 11 8 0,000 9,638E-03 0,02969249 ! blastocyst growth GO:0001832 19 8 0,000 9,638E-03 0,0296551 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,638E-03 0,0296178 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,638E-03 0,02958059 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 9,638E-03 0,02954347 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,638E-03 0,02950645 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 9,638E-03 0,02946952 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 9,638E-03 0,02943269 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 9,638E-03 0,02939594 ! amino sugar catabolic process GO:0046348 11 8 0,000 9,638E-03 0,02935929 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 9,638E-03 0,02932272 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,638E-03 0,02928625 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 9,638E-03 0,02924987 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 9,638E-03 0,02921358 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,638E-03 0,02917738 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 9,638E-03 0,02914127 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 9,638E-03 0,02910525 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,638E-03 0,02906932 ! NAD biosynthetic process GO:0009435 17 8 0,000 9,638E-03 0,02903347 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 9,638E-03 0,02899772 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 9,638E-03 0,02896205 ! axon extension GO:0048675 16 9 0,000 0,01083659 0,03252308 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01083659 0,03248317 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01083659 0,03244336 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01083659 0,03240365 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01083659 0,03236404 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01083659 0,03232452 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01083659 0,0322851 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01083659 0,03224578 ! reproductive behavior GO:0019098 22 9 0,000 0,01083659 0,03220655 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01083659 0,03216742 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01083659 0,03212838 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01083659 0,03208944 ! UTP metabolic process GO:0046051 10 9 0,000 0,01083659 0,03205059 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01083659 0,03201183 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01083659 0,03197317 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01083659 0,0319346 ! artery development GO:0060840 25 9 0,000 0,01083659 0,03189613 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01083659 0,03185774 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01083659 0,03181945 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01083659 0,03178125 ! equilibrioception GO:0050957 20 9 0,000 0,01083659 0,03174315 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01083659 0,03170513 ! chemosensory behavior GO:0007635 21 9 0,000 0,01083659 0,03166721 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01083659 0,03162937 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01083659 0,03159163 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01083659 0,03155398 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01083659 0,03151641 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01083659 0,03147894 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01083659 0,03144155 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01083659 0,03140425 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01083659 0,03136704 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01083659 0,03132992 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01083659 0,03129289 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01083659 0,03125594 ! protein targeting to ER GO:0045047 25 9 0,000 0,01083659 0,03121909 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01083659 0,03118231 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01083659 0,03114563 ! T cell selection GO:0045058 27 9 0,000 0,01083659 0,03110903 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01083659 0,03107252 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01083659 0,03103609 ! glycine catabolic process GO:0006546 15 9 0,000 0,01083659 0,03099975 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01083659 0,03096349 ! endosome organization GO:0007032 20 9 0,000 0,01083659 0,03092732 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01083659 0,03089123 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01083659 0,03085523 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01083659 0,03081931 ! mannose metabolic process GO:0006013 13 9 0,000 0,01083659 0,03078347 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01083659 0,03074772 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01083659 0,03071205 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01083659 0,03067646 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01083659 0,03064096 ! receptor clustering GO:0043113 20 9 0,000 0,01083659 0,03060553 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01083659 0,03057019 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01083659 0,03053493 ! retinol metabolic process GO:0042572 20 9 0,000 0,01083659 0,03049975 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01083659 0,03046466 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01083659 0,03042964 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01083659 0,0303947 ! macrophage differentiation GO:0030225 15 9 0,000 0,01083659 0,03035985 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01083659 0,03032507 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01083659 0,03029037 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01083659 0,03025575 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01083659 0,03022122 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01083659 0,03018676 ! response to amine stimulus GO:0014075 13 9 0,000 0,01083659 0,03015237 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01083659 0,03011807 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01083659 0,03008385 ! erythrocyte development GO:0048821 17 9 0,000 0,01083659 0,0300497 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01083659 0,03001563 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01083659 0,02998164 ! renal water homeostasis GO:0003091 15 9 0,000 0,01083659 0,02994772 ! postreplication repair GO:0006301 25 9 0,000 0,01083659 0,02991388 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01083659 0,02988012 ! icosanoid secretion GO:0032309 15 9 0,000 0,01083659 0,02984643 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01083659 0,02981282 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01083659 0,02977929 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01083659 0,02974583 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01083659 0,02971244 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01083659 0,02967913 ! sterol catabolic process GO:0016127 14 9 0,000 0,01083659 0,0296459 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01083659 0,02961274 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01083659 0,02957965 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01083659 0,02954664 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01083659 0,0295137 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01083659 0,02948083 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01083659 0,02944804 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01083659 0,02941532 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01083659 0,02938267 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01083659 0,02935009 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01083659 0,02931759 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01083659 0,02928516 ! purine base metabolic process GO:0006144 25 9 0,000 0,01083659 0,0292528 ! pigment granule transport GO:0051904 17 9 0,000 0,01083659 0,02922051 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01083659 0,0291883 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01083659 0,02915615 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01083659 0,02912408 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01083659 0,02909207 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01083659 0,02906014 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01083659 0,02902827 ! mitochondrion localization GO:0051646 18 9 0,000 0,01083659 0,02899648 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01203355 0,03216407 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01203355 0,03212892 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01203355 0,03209385 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01203355 0,03205885 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01203355 0,03202392 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01203355 0,03198908 ! associative learning GO:0008306 21 10 0,000 0,01203355 0,03195431 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01203355 0,03191961 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01203355 0,03188499 ! phosphate transport GO:0006817 24 10 0,000 0,01203355 0,03185045 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01203355 0,03181598 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01203355 0,03178158 ! CTP metabolic process GO:0046036 11 10 0,000 0,01203355 0,03174726 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01203355 0,03171301 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01203355 0,03167884 ! GTP metabolic process GO:0046039 11 10 0,000 0,01203355 0,03164474 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01203355 0,03161071 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01203355 0,03157676 ! social behavior GO:0035176 29 10 0,000 0,01203355 0,03154288 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01203355 0,03150907 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01203355 0,03147533 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01203355 0,03144167 ! androgen metabolic process GO:0008209 17 10 0,000 0,01203355 0,03140808 ! phospholipid efflux GO:0033700 19 10 0,000 0,01203355 0,03137456 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01203355 0,03134111 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01203355 0,03130773 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01203355 0,03127443 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01203355 0,03124119 ! lung alveolus development GO:0048286 26 10 0,000 0,01203355 0,03120803 ! pathogenesis GO:0009405 17 10 0,000 0,01203355 0,03117493 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01203355 0,03114191 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01203355 0,03110895 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01203355 0,03107607 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01203355 0,03104325 ! endoderm development GO:0007492 18 10 0,000 0,01203355 0,03101051 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01203355 0,03097783 ! arginine catabolic process GO:0006527 17 10 0,000 0,01203355 0,03094522 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01203355 0,03091268 ! proline metabolic process GO:0006560 13 10 0,000 0,01203355 0,03088021 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01203355 0,03084781 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01203355 0,03081547 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01203355 0,03078321 ! V(D)J recombination GO:0033151 34 10 0,000 0,01203355 0,03075101 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01203355 0,03071887 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01203355 0,03068681 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01203355 0,03065481 ! B cell proliferation GO:0042100 19 10 0,000 0,01203355 0,03062288 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01203355 0,03059101 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01203355 0,03055921 ! multicellular organism growth GO:0035264 19 10 0,000 0,01203355 0,03052748 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01203355 0,03049581 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01203355 0,03046421 ! ruffle organization GO:0031529 17 10 0,000 0,01203355 0,03043267 ! epithelial cell development GO:0002064 21 10 0,000 0,01203355 0,0304012 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01203355 0,0303698 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01203355 0,03033845 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01203355 0,03030718 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01203355 0,03027597 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01203355 0,03024482 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01203355 0,03021373 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01203355 0,03018271 ! motor axon guidance GO:0008045 22 10 0,000 0,01203355 0,03015176 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01203355 0,03012086 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01203355 0,03009003 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01203355 0,03005927 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01203355 0,03002856 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01203355 0,02999792 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01203355 0,02996734 ! segment specification GO:0007379 15 10 0,000 0,01203355 0,02993682 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01203355 0,02990637 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01203355 0,02987598 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01203355 0,02984565 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01203355 0,02981538 ! response to dsRNA GO:0043331 23 10 0,000 0,01203355 0,02978517 ! DNA ligation GO:0006266 18 10 0,000 0,01203355 0,02975502 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01203355 0,02972494 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01203355 0,02969491 ! melanosome localization GO:0032400 16 10 0,000 0,01203355 0,02966495 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01203355 0,02963504 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01203355 0,0296052 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01203355 0,02957541 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01203355 0,02954569 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01203355 0,02951603 ! induction of an organ GO:0001759 17 10 0,000 0,01203355 0,02948642 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01203355 0,02945688 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01203355 0,02942739 ! protein sumoylation GO:0016925 17 10 0,000 0,01203355 0,02939796 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01203355 0,02936859 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01203355 0,02933928 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01203355 0,02931003 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01203355 0,02928084 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01203355 0,0292517 ! salivary gland development GO:0007431 28 10 0,000 0,01203355 0,02922263 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01203355 0,02919361 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01203355 0,02916464 ! midbrain development GO:0030901 14 10 0,000 0,01203355 0,02913574 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01203355 0,02910689 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01203355 0,0290781 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01203355 0,02904937 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01203355 0,02902069 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01203355 0,02899207 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01203355 0,02896351 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01203355 0,028935 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01203355 0,02890655 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01203355 0,02887816 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01203355 0,02884982 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01203355 0,02882153 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01203355 0,0287933 ! blastocyst formation GO:0001825 18 10 0,000 0,01203355 0,02876513 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01203355 0,02873701 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01203355 0,02870895 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01203355 0,02868094 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01203355 0,02865298 ! response to nicotine GO:0035094 20 10 0,000 0,01203355 0,02862508 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01203355 0,02859724 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01203355 0,02856945 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0132291 0,03137736 ! respiratory burst GO:0045730 17 11 0,000 0,0132291 0,03134693 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0132291 0,03131655 ! neuron fate specification GO:0048665 18 11 0,000 0,0132291 0,03128624 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0132291 0,03125598 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0132291 0,03122578 ! thyroid gland development GO:0030878 26 11 0,000 0,0132291 0,03119564 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,0132291 0,03116556 ! synapsis GO:0007129 14 11 0,000 0,0132291 0,03113553 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0132291 0,03110557 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0132291 0,03107566 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,0132291 0,0310458 ! response to pain GO:0048265 27 11 0,000 0,0132291 0,03101601 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0132291 0,03098627 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0132291 0,03095659 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0132291 0,03092697 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0132291 0,0308974 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0132291 0,03086789 ! bone resorption GO:0045453 16 11 0,000 0,0132291 0,03083844 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0132291 0,03080904 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0132291 0,0307797 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0132291 0,03075041 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0132291 0,03072118 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0132291 0,03069201 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0132291 0,03066289 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0132291 0,03063382 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0132291 0,03060481 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0132291 0,03057586 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0132291 0,03054696 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0132291 0,03051811 ! UV protection GO:0009650 20 11 0,000 0,0132291 0,03048932 ! adult heart development GO:0007512 16 11 0,000 0,0132291 0,03046059 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0132291 0,0304319 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0132291 0,03040328 ! macroautophagy GO:0016236 19 11 0,000 0,0132291 0,0303747 ! temperature homeostasis GO:0001659 18 11 0,000 0,0132291 0,03034618 ! behavioral fear response GO:0001662 27 11 0,000 0,0132291 0,03031771 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0132291 0,0302893 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0132291 0,03026094 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0132291 0,03023263 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0132291 0,03020438 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0132291 0,03017617 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0132291 0,03014802 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0132291 0,03011993 ! regulation of organ growth GO:0046620 14 11 0,000 0,0132291 0,03009188 ! pigment granule localization GO:0051875 20 11 0,000 0,0132291 0,03006389 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0132291 0,03003595 ! vasoconstriction GO:0042310 20 11 0,000 0,0132291 0,03000806 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0132291 0,02998023 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0132291 0,02995244 ! embryonic axis specification GO:0000578 19 11 0,000 0,0132291 0,02992471 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0132291 0,02989702 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0132291 0,02986939 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0132291 0,02984181 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0132291 0,02981428 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0132291 0,0297868 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0132291 0,02975938 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0132291 0,029732 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0132291 0,02970467 ! prophase GO:0051324 17 11 0,000 0,0132291 0,02967739 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0132291 0,02965017 ! nucleosome positioning GO:0016584 15 11 0,000 0,0132291 0,02962299 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0132291 0,02959586 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0132291 0,02956879 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0132291 0,02954176 ! apical protein localization GO:0045176 18 11 0,000 0,0132291 0,02951478 ! acid secretion GO:0046717 20 11 0,000 0,0132291 0,02948785 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0132291 0,02946097 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0132291 0,02943414 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0132291 0,02940735 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0132291 0,02938062 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0132291 0,02935394 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0132291 0,0293273 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0132291 0,02930071 ! cholesterol efflux GO:0033344 21 11 0,000 0,0132291 0,02927417 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0132291 0,02924768 ! oocyte development GO:0048599 20 11 0,000 0,0132291 0,02922123 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0132291 0,02919484 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0132291 0,02916849 ! embryonic gut development GO:0048566 19 11 0,000 0,0132291 0,02914218 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0132291 0,02911593 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0132291 0,02908972 ! activation of innate immune response GO:0002218 16 11 0,000 0,0132291 0,02906356 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0132291 0,02903745 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0132291 0,02901138 ! lysogeny GO:0030069 22 11 0,000 0,0132291 0,02898537 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0132291 0,02895939 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0132291 0,02893347 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0132291 0,02890759 ! regulation of embryonic development GO:0045995 35 11 0,000 0,0132291 0,02888175 ! nucleus localization GO:0051647 22 11 0,000 0,0132291 0,02885597 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01442323 0,03143261 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01442323 0,03140459 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01442323 0,03137663 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01442323 0,03134871 ! virus-host interaction GO:0019048 30 12 0,000 0,01442323 0,03132085 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01442323 0,03129303 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01442323 0,03126526 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01442323 0,03123755 ! protein complex disassembly GO:0043241 28 12 0,000 0,01442323 0,03120988 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01442323 0,03118226 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01442323 0,03115469 ! hippocampus development GO:0021766 29 12 0,000 0,01442323 0,03112717 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01442323 0,03109969 ! T cell proliferation GO:0042098 32 12 0,000 0,01442323 0,03107227 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01442323 0,03104489 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01442323 0,03101756 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01442323 0,03099028 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01442323 0,03096305 ! drug transport GO:0015893 16 12 0,000 0,01442323 0,03093587 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01442323 0,03090873 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01442323 0,03088164 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01442323 0,0308546 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01442323 0,0308276 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01442323 0,03080066 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01442323 0,03077376 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01442323 0,0307469 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01442323 0,0307201 ! lipid digestion GO:0044241 21 12 0,000 0,01442323 0,03069334 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01442323 0,03066662 ! entry into host cell GO:0030260 34 12 0,000 0,01442323 0,03063996 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01442323 0,03061334 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01442323 0,03058676 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01442323 0,03056024 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01442323 0,03053375 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01442323 0,03050732 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01442323 0,03048093 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01442323 0,03045458 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01442323 0,03042828 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01442323 0,03040203 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01442323 0,03037582 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01442323 0,03034966 ! cranial nerve development GO:0021545 23 12 0,000 0,01442323 0,03032354 ! fucose catabolic process GO:0019317 25 12 0,000 0,01442323 0,03029746 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01442323 0,03027144 ! histone acetylation GO:0016573 27 12 0,000 0,01442323 0,03024545 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01442323 0,03021951 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01442323 0,03019362 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01442323 0,03016777 ! zymogen activation GO:0031638 18 12 0,000 0,01442323 0,03014196 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01442323 0,0301162 ! T cell homeostasis GO:0043029 28 12 0,000 0,01442323 0,03009048 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01442323 0,0300648 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01442323 0,03003917 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01442323 0,03001359 ! oocyte differentiation GO:0009994 21 12 0,000 0,01442323 0,02998804 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01442323 0,02996254 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01442323 0,02993709 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01442323 0,02991167 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01442323 0,0298863 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01442323 0,02986098 ! defense response to fungus GO:0050832 15 12 0,000 0,01442323 0,02983569 ! developmental induction GO:0031128 22 12 0,000 0,01442323 0,02981045 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01442323 0,02978525 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01442323 0,02976009 ! response to cold GO:0009409 17 12 0,000 0,01442323 0,02973498 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01442323 0,02970991 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01442323 0,02968488 ! localization within membrane GO:0051668 26 12 0,000 0,01442323 0,02965989 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01561595 0,03208559 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01561595 0,03205863 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01561595 0,03203171 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01561595 0,03200484 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01561595 0,03197801 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01561595 0,03195123 ! peroxisomal transport GO:0043574 28 13 0,000 0,01561595 0,03192449 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01561595 0,0318978 ! cartilage condensation GO:0001502 22 13 0,000 0,01561595 0,03187115 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01561595 0,03184455 ! organelle fusion GO:0048284 36 13 0,000 0,01561595 0,03181799 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01561595 0,03179148 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01561595 0,03176501 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01561595 0,03173858 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01561595 0,0317122 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01561595 0,03168586 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01561595 0,03165956 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01561595 0,03163331 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01561595 0,0316071 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01561595 0,03158094 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01561595 0,03155481 ! methionine metabolic process GO:0006555 31 13 0,000 0,01561595 0,03152874 ! plasma membrane organization GO:0007009 27 13 0,000 0,01561595 0,0315027 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01561595 0,03147671 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01561595 0,03145076 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01561595 0,03142485 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01561595 0,03139899 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01561595 0,03137317 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01561595 0,03134739 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01561595 0,03132165 ! exocrine system development GO:0035272 34 13 0,000 0,01561595 0,03129596 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01561595 0,0312703 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01561595 0,03124469 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01561595 0,03121913 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01561595 0,0311936 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01561595 0,03116811 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01561595 0,03114267 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01561595 0,03111727 ! protein homotetramerization GO:0051289 24 13 0,000 0,01561595 0,03109191 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01561595 0,03106659 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01561595 0,03104131 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01561595 0,03101607 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01561595 0,03099088 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01561595 0,03096572 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01561595 0,03094061 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01561595 0,03091554 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01561595 0,0308905 ! histone methylation GO:0016571 29 13 0,000 0,01561595 0,03086551 ! chromatin silencing GO:0006342 29 13 0,000 0,01561595 0,03084056 ! gland morphogenesis GO:0022612 31 13 0,000 0,01561595 0,03081565 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01561595 0,03079078 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01561595 0,03076594 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01561595 0,03074115 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01561595 0,0307164 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01561595 0,03069169 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01561595 0,03066702 ! spleen development GO:0048536 24 13 0,000 0,01561595 0,03064239 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01561595 0,03061779 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01561595 0,03059324 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01561595 0,03056873 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01561595 0,03054425 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01561595 0,03051982 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01561595 0,03049542 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01561595 0,03047106 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01561595 0,03044674 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01561595 0,03042247 ! insulin secretion GO:0030073 24 13 0,000 0,01561595 0,03039822 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01561595 0,03037402 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01561595 0,03034986 ! acrosome reaction GO:0007340 19 13 0,000 0,01561595 0,03032573 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01561595 0,03030165 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01561595 0,0302776 ! rRNA transcription GO:0009303 28 14 0,000 0,01680726 0,03256158 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01680726 0,03253577 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01680726 0,03251001 ! water transport GO:0006833 21 14 0,000 0,01680726 0,03248429 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01680726 0,03245861 ! non-recombinational repair GO:0000726 29 14 0,000 0,01680726 0,03243298 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01680726 0,03240738 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01680726 0,03238182 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01680726 0,0323563 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01680726 0,03233082 ! lipid localization GO:0010876 32 14 0,000 0,01680726 0,03230539 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01680726 0,03227999 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01680726 0,03225463 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01680726 0,03222931 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01680726 0,03220404 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01680726 0,0321788 ! arginine metabolic process GO:0006525 21 14 0,000 0,01680726 0,0321536 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01680726 0,03212844 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01680726 0,03210332 ! regulation of heart rate GO:0002027 25 14 0,000 0,01680726 0,03207824 ! fear response GO:0042596 34 14 0,000 0,01680726 0,0320532 ! organic alcohol transport GO:0015850 29 14 0,000 0,01680726 0,0320282 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01680726 0,03200323 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01680726 0,03197831 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01680726 0,03195342 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01680726 0,03192857 ! bone mineralization GO:0030282 18 14 0,000 0,01680726 0,03190377 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01680726 0,031879 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01680726 0,03185426 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01680726 0,03182957 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01680726 0,03180492 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01680726 0,0317803 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01680726 0,03175572 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01680726 0,03173118 ! ribosome assembly GO:0042255 18 14 0,000 0,01680726 0,03170668 ! cerebellum development GO:0021549 23 14 0,000 0,01680726 0,03168221 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01680726 0,03165778 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01680726 0,0316334 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01680726 0,03160904 ! response to gamma radiation GO:0010332 30 14 0,000 0,01680726 0,03158473 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01680726 0,03156045 ! NADP metabolic process GO:0006739 24 14 0,000 0,01680726 0,03153621 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01680726 0,03151201 ! oxygen transport GO:0015671 22 14 0,000 0,01680726 0,03148784 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01680726 0,03146371 ! male genitalia development GO:0030539 26 14 0,000 0,01680726 0,03143962 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01680726 0,03141557 ! regulation of axon extension GO:0030516 43 14 0,000 0,01680726 0,03139155 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01680726 0,03136757 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01680726 0,03134362 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01680726 0,03131972 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01799717 0,0335115 ! lactation GO:0007595 30 15 0,000 0,01799717 0,03348597 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01799717 0,03346049 ! reproductive cellular process GO:0048610 22 15 0,000 0,01799717 0,03343504 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01799717 0,03340964 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01799717 0,03338427 ! superoxide anion generation GO:0042554 22 15 0,000 0,01799717 0,03335894 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01799717 0,03333365 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01799717 0,0333084 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01799717 0,03328318 ! copper ion transport GO:0006825 22 15 0,000 0,01799717 0,033258 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01799717 0,03323287 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01799717 0,03320777 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01799717 0,0331827 ! sulfate transport GO:0008272 27 15 0,000 0,01799717 0,03315768 ! response to cAMP GO:0051591 25 15 0,000 0,01799717 0,03313269 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01799717 0,03310774 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01799717 0,03308283 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01799717 0,03305796 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01799717 0,03303312 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01799717 0,03300832 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01799717 0,03298356 ! vesicle coating GO:0006901 38 15 0,000 0,01799717 0,03295883 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01799717 0,03293414 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01799717 0,03290949 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01799717 0,03288488 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01799717 0,0328603 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01799717 0,03283576 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01799717 0,03281126 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01799717 0,03278679 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01799717 0,03276236 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01799717 0,03273796 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01799717 0,0327136 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01799717 0,03268928 ! histone deacetylation GO:0016575 24 15 0,000 0,01799717 0,03266499 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01799717 0,03264074 ! water homeostasis GO:0030104 28 15 0,000 0,01799717 0,03261653 ! cofactor transport GO:0051181 30 15 0,000 0,01799717 0,03259235 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01799717 0,03256821 ! muscle maintenance GO:0046716 26 15 0,000 0,01799717 0,0325441 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01799717 0,03252003 ! intestinal absorption GO:0050892 31 15 0,000 0,01799717 0,032496 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01799717 0,032472 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01799717 0,03244803 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01799717 0,0324241 ! cell killing GO:0001906 32 15 0,000 0,01799717 0,03240021 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01799717 0,03237635 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01799717 0,03235253 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01799717 0,03232874 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01799717 0,03230498 ! actin filament polymerization GO:0030041 27 15 0,000 0,01799717 0,03228126 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01799717 0,03225758 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01918567 0,0343626 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01918567 0,03433742 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01918567 0,03431228 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01918567 0,03428718 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01918567 0,03426212 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01918567 0,03423709 ! bone remodeling GO:0046849 28 16 0,000 0,01918567 0,0342121 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01918567 0,03418715 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01918567 0,03416223 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01918567 0,03413735 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01918567 0,0341125 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01918567 0,0340877 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01918567 0,03406292 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01918567 0,03403819 ! startle response GO:0001964 28 16 0,000 0,01918567 0,03401348 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01918567 0,03398882 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01918567 0,03396419 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01918567 0,0339396 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01918567 0,03391504 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01918567 0,03389051 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01918567 0,03386603 ! pituitary gland development GO:0021983 30 16 0,000 0,01918567 0,03384157 ! lysosomal transport GO:0007041 31 16 0,000 0,01918567 0,03381716 ! fructose metabolic process GO:0006000 25 16 0,000 0,01918567 0,03379278 ! L-amino acid transport GO:0015807 33 16 0,000 0,01918567 0,03376843 ! stem cell development GO:0048864 46 16 0,000 0,01918567 0,03374412 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01918567 0,03371984 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01918567 0,0336956 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01918567 0,03367139 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01918567 0,03364722 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01918567 0,03362309 ! axon cargo transport GO:0008088 46 16 0,000 0,01918567 0,03359898 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01918567 0,03357491 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01918567 0,03355088 ! DNA replication initiation GO:0006270 28 16 0,000 0,01918567 0,03352688 ! neuron recognition GO:0008038 40 16 0,000 0,01918567 0,03350292 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01918567 0,03347899 ! tissue regeneration GO:0042246 27 16 0,000 0,01918567 0,03345509 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01918567 0,03343123 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01918567 0,0334074 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01918567 0,0333836 ! biomineral formation GO:0031214 22 16 0,000 0,01918567 0,03335984 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01918567 0,03333612 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01918567 0,03331242 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01918567 0,03328877 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01918567 0,03326514 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01918567 0,03324155 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01918567 0,03321799 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01918567 0,03319446 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01918567 0,03317097 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01918567 0,03314751 ! peptide hormone processing GO:0016486 27 16 0,000 0,01918567 0,03312409 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02037276 0,03514876 ! metencephalon development GO:0022037 32 17 0,000 0,02037276 0,03512396 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02037276 0,03509919 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02037276 0,03507445 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02037276 0,03504975 ! filopodium assembly GO:0046847 42 17 0,000 0,02037276 0,03502509 ! endothelial cell migration GO:0043542 31 17 0,000 0,02037276 0,03500046 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02037276 0,03497586 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02037276 0,0349513 ! glial cell development GO:0021782 28 17 0,000 0,02037276 0,03492677 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02037276 0,03490228 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02037276 0,03487782 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02037276 0,03485339 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02037276 0,034829 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02037276 0,03480465 ! myoblast differentiation GO:0045445 50 17 0,000 0,02037276 0,03478033 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02037276 0,03475604 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02037276 0,03473178 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02037276 0,03470756 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02037276 0,03468338 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02037276 0,03465923 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02037276 0,03463511 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02037276 0,03461102 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02037276 0,03458697 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02037276 0,03456295 ! membrane budding GO:0006900 42 17 0,000 0,02037276 0,03453896 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02037276 0,03451501 ! regulation of protein binding GO:0043393 33 17 0,000 0,02037276 0,03449109 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02037276 0,03446721 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02037276 0,03444335 ! genitalia development GO:0048806 32 17 0,000 0,02037276 0,03441954 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02037276 0,03439575 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02037276 0,03437199 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02037276 0,03434827 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02037276 0,03432458 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02037276 0,03430093 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02037276 0,03427731 ! steroid catabolic process GO:0006706 34 17 0,000 0,02037276 0,03425371 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02037276 0,03423016 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02037276 0,03420663 ! gas transport GO:0015669 26 17 0,000 0,02037276 0,03418314 ! organic cation transport GO:0015695 32 17 0,000 0,02037276 0,03415968 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02037276 0,03413625 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02037276 0,03411285 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02037276 0,03408948 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02155845 0,03604879 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02155845 0,03602414 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02155845 0,03599951 ! limbic system development GO:0021761 40 18 0,000 0,02155845 0,03597492 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02155845 0,03595037 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02155845 0,03592584 ! adult walking behavior GO:0007628 36 18 0,000 0,02155845 0,03590135 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02155845 0,0358769 ! heart looping GO:0001947 34 18 0,000 0,02155845 0,03585248 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02155845 0,03582809 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02155845 0,03580373 ! centrosome cycle GO:0007098 26 18 0,000 0,02155845 0,03577941 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02155845 0,03575512 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02155845 0,03573086 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02155845 0,03570663 ! glycine metabolic process GO:0006544 30 18 0,000 0,02155845 0,03568244 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02155845 0,03565828 ! response to retinoic acid GO:0032526 31 18 0,000 0,02155845 0,03563416 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02155845 0,03561006 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02155845 0,035586 ! DNA integration GO:0015074 32 18 0,000 0,02155845 0,03556198 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02155845 0,03553798 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02155845 0,03551402 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02155845 0,03549008 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02155845 0,03546619 ! neural crest cell migration GO:0001755 41 18 0,000 0,02155845 0,03544232 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02155845 0,03541848 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02155845 0,03539468 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02155845 0,03537091 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02155845 0,03534717 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02155845 0,03532346 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02155845 0,03529979 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02155845 0,03527615 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02155845 0,03525253 ! detection of bacterium GO:0016045 22 18 0,000 0,02155845 0,03522895 ! nerve development GO:0021675 34 18 0,000 0,02155845 0,03520541 ! defense response to virus GO:0051607 43 18 0,000 0,02155845 0,03518189 ! microspike assembly GO:0030035 46 18 0,000 0,02155845 0,0351584 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02155845 0,03513495 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02155845 0,03511152 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02274273 0,03701566 ! positive regulation of translation GO:0045727 31 19 0,000 0,02274273 0,03699101 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02274273 0,0369664 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02274273 0,03694182 ! neuron maturation GO:0042551 46 19 0,000 0,02274273 0,03691728 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02274273 0,03689276 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02274273 0,03686828 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02274273 0,03684383 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02274273 0,03681942 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02274273 0,03679503 ! inositol metabolic process GO:0006020 33 19 0,000 0,02274273 0,03677068 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02274273 0,03674636 ! memory GO:0007613 34 19 0,000 0,02274273 0,03672208 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02274273 0,03669782 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02274273 0,0366736 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02274273 0,03664941 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02274273 0,03662525 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02274273 0,03660112 ! cerebral cortex development GO:0021987 40 19 0,000 0,02274273 0,03657702 ! pigmentation during development GO:0048066 42 19 0,000 0,02274273 0,03655296 ! response to vitamin A GO:0033189 32 19 0,000 0,02274273 0,03652893 ! heme metabolic process GO:0042168 40 19 0,000 0,02274273 0,03650493 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02274273 0,03648096 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02274273 0,03645702 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02274273 0,03643311 ! response to fungus GO:0009620 26 19 0,000 0,02274273 0,03640924 ! peptide cross-linking GO:0018149 39 19 0,000 0,02274273 0,0363854 ! protein export from nucleus GO:0006611 40 19 0,000 0,02274273 0,03636158 ! heart process GO:0003015 32 19 0,000 0,02274273 0,0363378 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02274273 0,03631405 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02274273 0,03629033 ! visual learning GO:0008542 38 19 0,000 0,02274273 0,03626664 ! cellular pigmentation GO:0033059 37 19 0,000 0,02274273 0,03624299 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02274273 0,03621936 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02274273 0,03619577 ! vitamin transport GO:0051180 31 19 0,000 0,02274273 0,0361722 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02274273 0,03614867 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02274273 0,03612516 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02274273 0,03610169 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02274273 0,03607825 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02274273 0,03605483 ! cilium assembly GO:0042384 38 19 0,000 0,02274273 0,03603145 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02274273 0,0360081 ! protein secretion GO:0009306 45 20 0,000 0,02392562 0,03785641 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02392562 0,0378319 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02392562 0,03780743 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02392562 0,03778299 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02392562 0,03775859 ! skin development GO:0043588 42 20 0,000 0,02392562 0,03773421 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02392562 0,03770987 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02392562 0,03768555 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02392562 0,03766127 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02392562 0,03763702 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02392562 0,0376128 ! response to vitamin GO:0033273 36 20 0,000 0,02392562 0,03758861 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02392562 0,03756446 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02392562 0,03754033 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02392562 0,03751623 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02392562 0,03749217 ! response to alkaloid GO:0043279 38 20 0,000 0,02392562 0,03746814 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02392562 0,03744413 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02392562 0,03742016 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02392562 0,03739622 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02392562 0,03737231 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02392562 0,03734843 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02392562 0,03732458 ! body fluid secretion GO:0007589 33 20 0,000 0,02392562 0,03730076 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02392562 0,03727697 ! peptide secretion GO:0002790 38 20 0,000 0,02392562 0,03725321 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02392562 0,03722949 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02392562 0,03720579 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02392562 0,03718212 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02392562 0,03715848 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02392562 0,03713487 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02392562 0,0371113 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02392562 0,03708775 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02392562 0,03706423 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02392562 0,03704074 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02392562 0,03701728 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02392562 0,03699386 ! regulation of glucose import GO:0046324 30 20 0,000 0,02392562 0,03697046 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02392562 0,03694709 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02392562 0,03692375 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02392562 0,03690044 ! negative regulation of translation GO:0017148 32 20 0,000 0,02392562 0,03687716 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02392562 0,0368539 ! regulation of cell killing GO:0031341 46 21 0,000 0,02510711 0,03864944 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02510711 0,03862511 ! hormone secretion GO:0046879 39 21 0,000 0,02510711 0,0386008 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02510711 0,03857652 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02510711 0,03855227 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02510711 0,03852806 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02510711 0,03850387 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02510711 0,03847972 ! ovarian follicle development GO:0001541 39 21 0,000 0,02510711 0,03845559 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02510711 0,0384315 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02510711 0,03840743 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02510711 0,0383834 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02510711 0,03835939 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02510711 0,03833542 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02510711 0,03831147 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02510711 0,03828756 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02510711 0,03826367 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02510711 0,03823982 ! sensory perception of pain GO:0019233 33 21 0,000 0,02510711 0,03821599 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02510711 0,0381922 ! diencephalon development GO:0021536 36 21 0,000 0,02510711 0,03816843 ! collagen fibril organization GO:0030199 62 21 0,000 0,02510711 0,03814469 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02510711 0,03812099 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02510711 0,03809731 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02510711 0,03807366 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02510711 0,03805004 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02510711 0,03802645 ! collagen catabolic process GO:0030574 29 21 0,000 0,02510711 0,03800289 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02510711 0,03797936 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02510711 0,03795586 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02510711 0,03793239 ! actin filament-based movement GO:0030048 47 21 0,000 0,02510711 0,03790894 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02510711 0,03788553 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,0262872 0,03964175 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,0262872 0,03961729 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,0262872 0,03959287 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,0262872 0,03956847 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,0262872 0,03954411 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,0262872 0,03951977 ! microtubule-based transport GO:0010970 59 22 0,000 0,0262872 0,03949547 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,0262872 0,03947119 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,0262872 0,03944695 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,0262872 0,03942273 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,0262872 0,03939855 ! cellular response to starvation GO:0009267 37 22 0,000 0,0262872 0,03937439 ! vacuolar transport GO:0007034 41 22 0,000 0,0262872 0,03935027 ! central nervous system neuron development GO:0021954 47 22 0,000 0,0262872 0,03932617 ! fucose metabolic process GO:0006004 44 22 0,000 0,0262872 0,0393021 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,0262872 0,03927806 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,0262872 0,03925405 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,0262872 0,03923008 ! ureteric bud development GO:0001657 50 22 0,000 0,0262872 0,03920613 ! cell aging GO:0007569 48 22 0,000 0,0262872 0,0391822 ! stem cell differentiation GO:0048863 57 22 0,000 0,0262872 0,03915831 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,0262872 0,03913445 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,0262872 0,03911062 ! cytolysis GO:0019835 27 22 0,000 0,0262872 0,03908681 ! renal system process GO:0003014 42 22 0,000 0,0262872 0,03906304 ! vasodilation GO:0042311 40 22 0,000 0,0262872 0,03903929 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,0262872 0,03901557 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,0262872 0,03899188 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,0262872 0,03896822 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,0262872 0,03894459 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,0262872 0,03892099 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,0262872 0,03889742 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,0262872 0,03887387 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,0262872 0,03885035 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,0262872 0,03882686 ! sarcomere organization GO:0045214 32 22 0,000 0,0262872 0,0388034 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,0262872 0,03877997 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,0262872 0,03875657 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,0262872 0,03873319 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,0262872 0,03870985 ! gut development GO:0048565 44 22 0,000 0,0262872 0,03868653 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,0262872 0,03866323 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,0262872 0,03863997 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,0262872 0,03861674 ! protein stabilization GO:0050821 41 22 0,000 0,0262872 0,03859353 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,0274659 0,04029981 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0274659 0,04027562 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0274659 0,04025146 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0274659 0,04022733 ! gluconeogenesis GO:0006094 38 23 0,000 0,0274659 0,04020323 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0274659 0,04017915 ! viral genome replication GO:0019079 44 23 0,000 0,0274659 0,04015511 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0274659 0,04013109 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0274659 0,04010711 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,0274659 0,04008315 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0274659 0,04005922 ! regeneration GO:0031099 42 23 0,000 0,0274659 0,04003532 ! axis specification GO:0009798 43 23 0,000 0,0274659 0,04001144 ! visual behavior GO:0007632 46 23 0,000 0,0274659 0,0399876 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,0274659 0,03996378 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0274659 0,03993999 ! response to ethanol GO:0045471 47 23 0,000 0,0274659 0,03991623 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0274659 0,0398925 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0274659 0,0398688 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0274659 0,03984512 ! peroxisome organization GO:0007031 43 23 0,000 0,0274659 0,03982148 ! lysosome organization GO:0007040 47 23 0,000 0,0274659 0,03979786 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0274659 0,03977427 ! vesicle targeting GO:0006903 49 23 0,000 0,0274659 0,0397507 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,0274659 0,03972717 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0274659 0,03970366 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0274659 0,03968018 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0274659 0,03965673 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0274659 0,03963331 ! DNA modification GO:0006304 36 23 0,000 0,0274659 0,03960991 ! fatty acid transport GO:0015908 47 23 0,000 0,0274659 0,03958654 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0274659 0,0395632 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,0274659 0,03953989 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0274659 0,0395166 ! hormone transport GO:0009914 41 23 0,000 0,0274659 0,03949334 ! cell-cell recognition GO:0009988 28 23 0,000 0,0274659 0,03947011 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0274659 0,03944691 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0274659 0,03942373 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0274659 0,03940058 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0286432 0,04106534 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0286432 0,04104125 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0286432 0,0410172 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0286432 0,04099317 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0286432 0,04096917 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0286432 0,0409452 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0286432 0,04092125 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0286432 0,04089733 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0286432 0,04087345 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0286432 0,04084958 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0286432 0,04082575 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0286432 0,04080195 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0286432 0,04077817 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0286432 0,04075442 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0286432 0,0407307 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0286432 0,040707 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0286432 0,04068334 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0286432 0,0406597 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0286432 0,04063608 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0286432 0,0406125 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0286432 0,04058894 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,0286432 0,04056541 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0286432 0,04054191 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0286432 0,04051844 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0286432 0,04049499 ! membrane depolarization GO:0051899 45 24 0,000 0,0286432 0,04047157 ! pallium development GO:0021543 56 24 0,000 0,0286432 0,04044817 ! oogenesis GO:0048477 44 24 0,000 0,0286432 0,04042481 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0286432 0,04040147 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0286432 0,04037815 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0286432 0,04035487 ! platelet activation GO:0030168 41 24 0,000 0,0286432 0,04033161 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0286432 0,04030837 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0286432 0,04028517 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0286432 0,04026199 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0286432 0,04023884 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0286432 0,04021571 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0286432 0,04019261 ! regulation of amine transport GO:0051952 41 24 0,000 0,0286432 0,04016954 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0286432 0,04014649 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02981911 0,04177069 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,02981911 0,04174676 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02981911 0,04172285 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,02981911 0,04169896 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02981911 0,04167511 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02981911 0,04165128 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02981911 0,04162748 ! phototransduction GO:0007602 37 25 0,000 0,02981911 0,04160371 ! keratinization GO:0031424 37 25 0,000 0,02981911 0,04157996 ! vasculogenesis GO:0001570 49 25 0,000 0,02981911 0,04155624 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02981911 0,04153255 ! vacuole organization GO:0007033 49 25 0,000 0,02981911 0,04150888 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02981911 0,04148524 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02981911 0,04146163 ! receptor metabolic process GO:0043112 53 25 0,000 0,02981911 0,04143805 ! chromosome condensation GO:0030261 48 25 0,000 0,02981911 0,04141449 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02981911 0,04139096 ! regulation of behavior GO:0050795 48 25 0,000 0,02981911 0,04136745 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02981911 0,04134398 ! interaction with host GO:0051701 66 25 0,000 0,02981911 0,04132053 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02981911 0,0412971 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02981911 0,0412737 ! immunoglobulin production GO:0002377 62 25 0,000 0,02981911 0,04125033 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02981911 0,04122699 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02981911 0,04120367 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02981911 0,04118038 ! liver development GO:0001889 55 25 0,000 0,02981911 0,04115711 ! protein tetramerization GO:0051262 57 25 0,000 0,02981911 0,04113387 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03099363 0,04272993 ! myelination GO:0042552 50 26 0,000 0,03099363 0,04270583 ! initiation of viral infection GO:0019059 60 26 0,000 0,03099363 0,04268176 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03099363 0,04265771 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03099363 0,04263369 ! molting cycle process GO:0022404 52 26 0,000 0,03099363 0,0426097 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03099363 0,04258574 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03099363 0,0425618 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03099363 0,04253789 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03099363 0,042514 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03099363 0,04249015 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03099363 0,04246632 ! digestive system process GO:0022600 49 26 0,000 0,03099363 0,04244251 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03099363 0,04241873 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03099363 0,04239498 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03099363 0,04237126 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03099363 0,04234756 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03099363 0,04232389 ! neural crest cell development GO:0014032 59 26 0,000 0,03099363 0,04230025 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03099363 0,04227663 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03099363 0,04225304 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03099363 0,04222947 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03099363 0,04220593 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03099363 0,04218242 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03099363 0,04215893 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03099363 0,04213547 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03099363 0,04211204 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03099363 0,04208863 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03099363 0,04206524 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03099363 0,04204189 ! blastocyst development GO:0001824 50 26 0,000 0,03099363 0,04201856 ! telomere organization GO:0032200 46 26 0,000 0,03099363 0,04199525 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03099363 0,04197197 ! neural tube closure GO:0001843 58 26 0,000 0,03099363 0,04194872 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03099363 0,04192549 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03099363 0,04190229 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03216676 0,04346427 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03216676 0,04344024 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03216676 0,04341624 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03216676 0,04339227 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03216676 0,04336832 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03216676 0,0433444 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03216676 0,04332051 ! iron ion transport GO:0006826 65 27 0,000 0,03216676 0,04329664 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03216676 0,0432728 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03216676 0,04324898 ! tube lumen formation GO:0035148 59 27 0,000 0,03216676 0,04322519 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03216676 0,04320143 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03216676 0,04317769 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03216676 0,04315398 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03216676 0,0431303 ! response to starvation GO:0042594 47 27 0,000 0,03216676 0,04310664 ! response to toxin GO:0009636 49 27 0,000 0,03216676 0,043083 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03216676 0,0430594 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03216676 0,04303582 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03216676 0,04301226 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03216676 0,04298873 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03216676 0,04296523 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03216676 0,04294175 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,03333851 0,04448169 ! neuron fate commitment GO:0048663 52 28 0,000 0,03333851 0,04445741 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03333851 0,04443315 ! vesicle docking GO:0048278 55 28 0,000 0,03333851 0,04440893 ! circadian rhythm GO:0007623 56 28 0,000 0,03333851 0,04438472 ! dendrite development GO:0016358 67 28 0,000 0,03333851 0,04436055 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03333851 0,0443364 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03333851 0,04431228 ! sperm motility GO:0030317 37 28 0,000 0,03333851 0,04428818 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03333851 0,04426411 ! base-excision repair GO:0006284 41 28 0,000 0,03333851 0,04424007 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03333851 0,04421605 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03333851 0,04419206 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03333851 0,0441681 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03333851 0,04414416 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03333851 0,04412024 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03333851 0,04409636 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03333851 0,04407249 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03333851 0,04404866 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03333851 0,04402485 ! lipid oxidation GO:0034440 48 28 0,000 0,03333851 0,04400106 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03333851 0,04397731 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03450886 0,04549658 ! translational initiation GO:0006413 66 29 0,000 0,03450886 0,04547204 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03450886 0,04544752 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03450886 0,04542304 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03450886 0,04539858 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03450886 0,04537414 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03450886 0,04534973 ! primary neural tube formation GO:0014020 61 29 0,000 0,03450886 0,04532535 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03450886 0,045301 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03450886 0,04527667 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03450886 0,04525236 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03450886 0,04522809 ! somitogenesis GO:0001756 52 29 0,000 0,03450886 0,04520384 ! synaptogenesis GO:0007416 46 29 0,000 0,03450886 0,04517961 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03450886 0,04515541 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03450886 0,04513124 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03567784 0,04663508 ! phenol metabolic process GO:0018958 56 30 0,000 0,03567784 0,04661014 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03567784 0,04658523 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03567784 0,04656034 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03567784 0,04653548 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03567784 0,04651065 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03567784 0,04648585 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03567784 0,04646107 ! acute-phase response GO:0006953 50 30 0,000 0,03567784 0,04643631 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03567784 0,04641159 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03567784 0,04638689 ! myofibril assembly GO:0030239 50 30 0,000 0,03567784 0,04636221 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03567784 0,04633756 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03567784 0,04631294 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03567784 0,04628835 ! cell fate determination GO:0001709 64 30 0,000 0,03567784 0,04626378 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03567784 0,04623924 ! phospholipid transport GO:0015914 65 30 0,000 0,03567784 0,04621472 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03567784 0,04619023 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03567784 0,04616576 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03567784 0,04614132 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03567784 0,04611691 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03567784 0,04609252 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03567784 0,04606816 ! regulation of coagulation GO:0050818 52 30 0,000 0,03567784 0,04604382 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03684543 0,04752555 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03684543 0,04750047 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03684543 0,04747541 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03684543 0,04745039 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03684543 0,04742539 ! ovulation cycle process GO:0022602 55 31 0,000 0,03684543 0,04740041 ! peptide transport GO:0015833 60 31 0,000 0,03684543 0,04737547 ! male gonad development GO:0008584 56 31 0,000 0,03684543 0,04735054 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03684543 0,04732565 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03684543 0,04730078 ! detection of light stimulus GO:0009583 44 31 0,000 0,03684543 0,04727594 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,03684543 0,04725112 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,03684543 0,04722633 ! natural killer cell activation GO:0030101 50 31 0,000 0,03684543 0,04720157 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03684543 0,04717683 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03684543 0,04715211 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03684543 0,04712743 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03684543 0,04710277 ! eye morphogenesis GO:0048592 65 31 0,000 0,03684543 0,04707813 ! response to heat GO:0009408 54 31 0,000 0,03684543 0,04705352 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03684543 0,04702894 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03801164 0,04849214 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03801164 0,04846683 ! collagen metabolic process GO:0032963 49 32 0,000 0,03801164 0,04844154 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03801164 0,04841629 ! spindle organization GO:0007051 50 32 0,000 0,03801164 0,04839106 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03801164 0,04836585 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03801164 0,04834068 ! metanephros development GO:0001656 81 32 0,000 0,03801164 0,04831553 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03801164 0,0482904 ! muscle cell development GO:0055001 52 32 0,000 0,03801164 0,0482653 ! mesoderm formation GO:0001707 73 32 0,000 0,03801164 0,04824023 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,03801164 0,04821518 ! ovulation cycle GO:0042698 57 32 0,000 0,03801164 0,04819016 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03801164 0,04816517 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03801164 0,0481402 ! hindbrain development GO:0030902 65 32 0,000 0,03801164 0,04811525 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03801164 0,04809034 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03801164 0,04806544 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03801164 0,04804058 ! gene silencing GO:0016458 71 32 0,000 0,03801164 0,04801574 ! regulation of pH GO:0006885 56 33 0,000 0,03917647 0,04946156 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,03917647 0,04943601 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,03917647 0,04941049 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,03917647 0,049385 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,03917647 0,04935953 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,03917647 0,04933408 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,03917647 0,04930867 ! response to ionizing radiation GO:0010212 74 33 0,000 0,03917647 0,04928328 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,03917647 0,04925791 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,03917647 0,04923257 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,03917647 0,04920726 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,03917647 0,04918197 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,03917647 0,04915671 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,03917647 0,04913148 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,03917647 0,04910627 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04033993 0,05053869 ! glial cell differentiation GO:0010001 67 34 0,000 0,04033993 0,05051278 ! post-embryonic development GO:0009791 76 34 0,000 0,04033993 0,05048691 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04033993 0,05046106 ! cholesterol transport GO:0030301 62 34 0,000 0,04033993 0,05043523 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04033993 0,05040943 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04033993 0,05038366 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04033993 0,05035792 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04033993 0,0503322 ! cell fate specification GO:0001708 56 34 0,000 0,04033993 0,0503065 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04033993 0,05028084 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04033993 0,0502552 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04033993 0,05022958 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04033993 0,05020399 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,041502 0,05162393 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,041502 0,05159766 ! negative regulation of secretion GO:0051048 68 35 0,000 0,041502 0,05157141 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,041502 0,05154519 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,041502 0,051519 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,041502 0,05149284 ! membrane docking GO:0022406 69 35 0,000 0,041502 0,0514667 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,041502 0,05144059 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,041502 0,0514145 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,041502 0,05138844 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,041502 0,05136241 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,041502 0,0513364 ! ceramide metabolic process GO:0006672 72 35 0,000 0,041502 0,05131042 ! telencephalon development GO:0021537 81 35 0,000 0,041502 0,05128447 ! sterol transport GO:0015918 63 35 0,000 0,041502 0,05125854 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,041502 0,05123264 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,041502 0,05120677 ! placenta development GO:0001890 53 35 0,000 0,041502 0,05118092 ! vesicle localization GO:0051648 70 35 0,000 0,041502 0,05115509 ! regulation of muscle development GO:0048634 82 36 0,000 0,04266271 0,05255925 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04266271 0,05253276 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04266271 0,05250629 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04266271 0,05247986 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04266271 0,05245344 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04266271 0,05242706 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04266271 0,0524007 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04266271 0,05237437 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04266271 0,05234806 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04266271 0,05232178 ! aerobic respiration GO:0009060 56 36 0,000 0,04266271 0,05229553 ! cytokine production GO:0001816 68 36 0,000 0,04266271 0,05226931 ! embryonic organ development GO:0048568 67 36 0,000 0,04266271 0,05224311 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04266271 0,05221693 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,04266271 0,05219078 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,04382204 0,0535822 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04382204 0,0535554 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04382204 0,05352862 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04382204 0,05350187 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04382204 0,05347514 ! odontogenesis GO:0042476 74 37 0,000 0,04382204 0,05344845 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04382204 0,05342178 ! tissue remodeling GO:0048771 78 37 0,000 0,04382204 0,05339513 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04382204 0,05336851 ! female gonad development GO:0008585 71 37 0,000 0,04382204 0,05334192 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04382204 0,05331536 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04382204 0,05328882 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,04382204 0,05326231 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04382204 0,05323582 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,04498 0,05461537 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04498 0,05458824 ! meiosis I GO:0007127 74 38 0,000 0,04498 0,05456114 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04498 0,05453406 ! organic anion transport GO:0015711 82 38 0,000 0,04498 0,05450701 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04498 0,05447999 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04498 0,05445299 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04498 0,05442602 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04498 0,05439908 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04498 0,05437216 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,04498 0,05434527 ! regulation of protein stability GO:0031647 77 38 0,000 0,04498 0,0543184 ! spermatid development GO:0007286 69 38 0,000 0,04498 0,05429157 ! glycogen metabolic process GO:0005977 63 38 0,000 0,04498 0,05426476 ! pigment metabolic process GO:0042440 87 38 0,000 0,04498 0,05423797 ! neural tube formation GO:0001841 79 38 0,000 0,04498 0,05421122 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04613659 0,05557775 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04613659 0,05555036 ! negative regulation of binding GO:0051100 71 39 0,000 0,04613659 0,055523 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04613659 0,05549566 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04613659 0,05546835 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04613659 0,05544106 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04613659 0,05541381 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04613659 0,05538658 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04613659 0,05535937 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,04613659 0,05533219 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04613659 0,05530504 ! glucan metabolic process GO:0044042 64 39 0,000 0,04613659 0,05527792 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04729181 0,05663426 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04729181 0,05660651 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04729181 0,05657879 ! learning GO:0007612 82 40 0,000 0,04729181 0,05655109 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04729181 0,05652343 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04729181 0,05649579 ! lipid homeostasis GO:0055088 75 40 0,000 0,04729181 0,05646817 ! mismatch repair GO:0006298 58 40 0,000 0,04729181 0,05644059 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04729181 0,05641303 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04729181 0,0563855 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04844566 0,05773305 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04844566 0,0577049 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04844566 0,05767678 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04844566 0,05764869 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,04844566 0,05762062 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04844566 0,05759258 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04844566 0,05756457 ! gliogenesis GO:0042063 91 41 0,000 0,04844566 0,05753658 ! feeding behavior GO:0007631 69 41 0,000 0,04844566 0,05750863 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04844566 0,0574807 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04844566 0,05745279 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04844566 0,05742492 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04844566 0,05739707 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04844566 0,05736925 ! spermatid differentiation GO:0048515 73 41 0,000 0,04844566 0,05734145 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04844566 0,05731368 ! RNA modification GO:0009451 64 41 0,000 0,04844566 0,05728594 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,04959815 0,05862036 ! ear morphogenesis GO:0042471 64 42 0,000 0,04959815 0,05859201 ! organic ether metabolic process GO:0018904 59 42 0,000 0,04959815 0,05856369 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,04959815 0,0585354 ! T cell differentiation GO:0030217 93 42 0,000 0,04959815 0,05850714 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,04959815 0,0584789 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,04959815 0,05845069 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,04959815 0,05842251 ! regulation of protein secretion GO:0050708 77 42 0,000 0,04959815 0,05839435 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,04959815 0,05836623 ! cytokinesis GO:0000910 84 42 0,000 0,04959815 0,05833812 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,04959815 0,05831005 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05074928 0,05963467 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05074928 0,059606 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05074928 0,05957736 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05074928 0,05954874 ! regulation of tube size GO:0035150 76 43 0,000 0,05074928 0,05952016 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05074928 0,0594916 ! glucose transport GO:0015758 66 43 0,000 0,05074928 0,05946306 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05074928 0,05943456 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05074928 0,05940608 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05074928 0,05937763 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05074928 0,0593492 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05074928 0,05932081 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05074928 0,05929244 ! segmentation GO:0035282 78 43 0,000 0,05074928 0,05926409 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05074928 0,05923578 ! neuron migration GO:0001764 85 43 0,000 0,05074928 0,05920749 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05074928 0,05917923 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05189904 0,06049111 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05189904 0,06046226 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05189904 0,06043344 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05189904 0,06040465 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05189904 0,06037589 ! hexose transport GO:0008645 68 44 0,000 0,05189904 0,06034715 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05189904 0,06031844 ! striated muscle contraction GO:0006941 85 44 0,000 0,05189904 0,06028976 ! phagocytosis GO:0006909 105 44 0,000 0,05189904 0,0602611 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05189904 0,06023248 ! double-strand break repair GO:0006302 85 44 0,000 0,05189904 0,06020387 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05304745 0,06150684 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05304745 0,06147766 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05304745 0,06144851 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,05304745 0,06141939 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05304745 0,06139029 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05304745 0,06136123 ! biopolymer methylation GO:0043414 91 45 0,000 0,05304745 0,06133219 ! B cell differentiation GO:0030183 124 45 0,000 0,05304745 0,06130317 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05304745 0,06127419 ! female gamete generation GO:0007292 71 45 0,000 0,05304745 0,06124523 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05304745 0,0612163 ! polyol metabolic process GO:0019751 77 45 0,000 0,05304745 0,0611874 ! developmental growth GO:0048589 88 45 0,000 0,05304745 0,06115852 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05304745 0,06112967 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05419449 0,06242204 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05419449 0,06239262 ! glycolysis GO:0006096 71 46 0,000 0,05419449 0,06236323 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05419449 0,06233387 ! leukocyte migration GO:0050900 75 46 0,000 0,05419449 0,06230454 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,05419449 0,06227523 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05419449 0,06224595 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05419449 0,0622167 ! pigmentation GO:0043473 103 46 0,000 0,05419449 0,06218748 ! cell growth GO:0016049 90 46 0,000 0,05419449 0,06215828 ! neural tube development GO:0021915 91 47 0,000 0,05534018 0,06344254 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05648451 0,06472404 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05648451 0,0646937 ! mitochondrial transport GO:0006839 94 48 0,000 0,05648451 0,06466338 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05648451 0,0646331 ! cellular component disassembly GO:0022411 89 48 0,000 0,05648451 0,06460284 ! endosome transport GO:0016197 127 48 0,000 0,05648451 0,06457261 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05648451 0,06454241 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05648451 0,06451223 ! male sex differentiation GO:0046661 93 48 0,000 0,05648451 0,06448209 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05648451 0,06445197 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05648451 0,06442188 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05648451 0,06439182 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05648451 0,06436178 ! methylation GO:0032259 97 48 0,000 0,05648451 0,06433178 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05762749 0,06560296 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05762749 0,06557241 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05762749 0,06554188 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,05762749 0,06551138 ! protein homooligomerization GO:0051260 84 49 0,000 0,05762749 0,06548091 ! regulation of action potential GO:0001508 102 50 0,000 0,05876912 0,06674707 ! regulation of ion transport GO:0043269 86 50 0,000 0,05876912 0,06671606 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,05876912 0,06668507 ! endocrine system development GO:0035270 109 50 0,000 0,05876912 0,06665411 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,05876912 0,06662318 ! activation of caspase activity GO:0006919 95 50 0,000 0,05876912 0,06659228 ! regulation of ossification GO:0030278 123 50 0,000 0,05876912 0,06656141 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,05876912 0,06653056 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,05876912 0,06649975 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,05876912 0,06646896 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,05876912 0,0664382 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,05876912 0,06640747 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,05990939 0,06766465 ! viral infectious cycle GO:0019058 104 51 0,000 0,05990939 0,06763338 ! peptide metabolic process GO:0006518 80 51 0,000 0,05990939 0,06760215 ! response to temperature stimulus GO:0009266 84 51 0,000 0,05990939 0,06757093 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,05990939 0,06753975 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,05990939 0,0675086 ! positive regulation of binding GO:0051099 88 52 0,000 0,06104832 0,06876028 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06104832 0,06872859 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06104832 0,06869693 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06104832 0,0686653 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06104832 0,0686337 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06104832 0,06860213 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06104832 0,06857059 ! excretion GO:0007588 87 52 0,000 0,06104832 0,06853908 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,06104832 0,0685076 ! histone modification GO:0016570 104 52 0,000 0,06104832 0,06847614 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06104832 0,06844472 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06104832 0,06841332 ! amino acid activation GO:0043038 98 52 0,000 0,06104832 0,06838195 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,0621859 0,06962426 ! positive regulation of growth GO:0045927 96 53 0,000 0,0621859 0,06959237 ! inner ear development GO:0048839 89 53 0,000 0,0621859 0,06956051 ! chromatin remodeling GO:0006338 122 53 0,000 0,0621859 0,06952867 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,0621859 0,06949686 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0621859 0,06946509 ! vesicle organization GO:0016050 127 53 0,000 0,0621859 0,06943334 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,0621859 0,06940162 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,0621859 0,06936993 ! synapse organization GO:0050808 102 53 0,000 0,0621859 0,06933827 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,06332213 0,07057297 ! regulation of translational initiation GO:0006446 87 54 0,000 0,06332213 0,07054079 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06332213 0,07050864 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06332213 0,07047652 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06332213 0,07044443 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06332213 0,07041236 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06332213 0,07038033 ! membrane fusion GO:0006944 122 54 0,000 0,06332213 0,07034832 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06332213 0,07031634 ! covalent chromatin modification GO:0016569 115 54 0,000 0,06332213 0,0702844 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06332213 0,07025248 ! regulation of cell shape GO:0008360 142 54 0,000 0,06332213 0,07022059 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,06332213 0,07018873 ! RNA catabolic process GO:0006401 103 55 0,000 0,06445701 0,07141428 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06445701 0,07138191 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06445701 0,07134956 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06445701 0,07131725 ! cell recognition GO:0008037 98 55 0,000 0,06445701 0,07128496 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06445701 0,07125271 ! cell maturation GO:0048469 107 55 0,000 0,06445701 0,07122048 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06445701 0,07118829 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06559056 0,07240747 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,06559056 0,07237477 ! glucose catabolic process GO:0006007 88 56 0,000 0,06559056 0,07234209 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06559056 0,07230945 ! regulation of DNA replication GO:0006275 105 56 0,000 0,06559056 0,07227683 ! RNA elongation GO:0006354 90 56 0,000 0,06559056 0,07224425 ! chloride transport GO:0006821 102 57 0,000 0,06672276 0,07345818 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06672276 0,07342509 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,06672276 0,07339203 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,06672276 0,073359 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06672276 0,073326 ! heart morphogenesis GO:0003007 105 57 0,000 0,06672276 0,07329303 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06672276 0,07326009 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06785362 0,07446829 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06785362 0,07443485 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06785362 0,07440144 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06785362 0,07436806 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06785362 0,07433471 ! aging GO:0007568 112 58 0,000 0,06785362 0,07430139 ! gastrulation GO:0007369 122 58 0,000 0,06785362 0,0742681 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06785362 0,07423484 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06785362 0,07420161 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06785362 0,07416841 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06785362 0,07413524 ! maintenance of location GO:0051235 124 58 0,000 0,06785362 0,0741021 ! nuclear export GO:0051168 110 59 0,000 0,06898315 0,07530198 ! establishment of organelle localization GO:0051656 122 59 0,000 0,06898315 0,07526835 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07011134 0,07646518 ! lipid modification GO:0030258 112 60 0,000 0,07011134 0,07643105 ! DNA catabolic process GO:0006308 94 60 0,000 0,07011134 0,07639696 ! regulation of endocytosis GO:0030100 104 60 0,000 0,07011134 0,0763629 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07011134 0,07632887 ! adult behavior GO:0030534 104 60 0,000 0,07011134 0,07629487 ! kidney development GO:0001822 133 60 0,000 0,07011134 0,07626091 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07123819 0,07745211 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07123819 0,07741766 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07123819 0,07738323 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07123819 0,07734884 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07123819 0,07731448 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07123819 0,07728015 ! camera-type eye development GO:0043010 126 61 0,000 0,07123819 0,07724585 ! proton transport GO:0015992 117 61 0,000 0,07123819 0,07721158 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07123819 0,07717734 ! viral reproductive process GO:0022415 132 62 0,000 0,07236371 0,07836194 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,07236371 0,07832722 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07236371 0,07829253 ! tRNA processing GO:0008033 102 62 0,000 0,07236371 0,07825787 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07236371 0,07822324 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07348789 0,07940333 ! regulation of mitosis GO:0007088 112 63 0,000 0,07348789 0,07936822 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,07348789 0,07933315 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07348789 0,07929811 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07348789 0,0792631 ! hydrogen transport GO:0006818 121 64 0,000 0,07461075 0,08043868 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07461075 0,0804032 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07461075 0,08036775 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07573227 0,08153986 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,07573227 0,08150394 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07573227 0,08146805 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07573227 0,08143219 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07573227 0,08139637 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,07573227 0,08136057 ! ear development GO:0043583 114 66 0,000 0,07685247 0,08252773 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,07685247 0,08249147 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,07685247 0,08245524 ! gonad development GO:0008406 115 66 0,000 0,07685247 0,08241905 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,07685247 0,08238288 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,07797134 0,08354561 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07797134 0,08350898 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,07797134 0,08347239 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,07797134 0,08343583 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07797134 0,0833993 ! secondary metabolic process GO:0019748 125 67 0,000 0,07797134 0,0833628 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07797134 0,08332633 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,07908889 0,08448367 ! hexose catabolic process GO:0019320 113 68 0,000 0,07908889 0,08444675 ! extracellular matrix organization GO:0030198 146 68 0,000 0,07908889 0,08440986 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,07908889 0,084373 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,07908889 0,08433617 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,07908889 0,08429937 ! viral reproduction GO:0016032 142 68 0,000 0,07908889 0,08426261 ! regulation of lipase activity GO:0060191 137 68 0,000 0,07908889 0,08422588 ! adaptive immune response GO:0002250 126 68 0,000 0,07908889 0,08418918 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,07908889 0,08415251 ! negative regulation of cell size GO:0045792 144 69 0,000 0,08020511 0,08530305 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08020511 0,08526592 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,08020511 0,08522884 ! lung development GO:0030324 165 69 0,000 0,08020511 0,08519178 ! urogenital system development GO:0001655 149 69 0,000 0,08020511 0,08515476 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08020511 0,08511777 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,08020511 0,08508081 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08020511 0,08504388 ! developmental maturation GO:0021700 128 69 0,000 0,08020511 0,08500698 ! single fertilization GO:0007338 83 69 0,000 0,08020511 0,08497012 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,08132002 0,08611392 ! cell redox homeostasis GO:0045454 114 70 0,000 0,08132002 0,0860766 ! germ cell development GO:0007281 133 70 0,000 0,08132002 0,08603933 ! activation of immune response GO:0002253 120 70 0,000 0,08132002 0,08600208 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,08132002 0,08596486 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,0824336 0,08710436 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,0824336 0,0870667 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,0824336 0,08702908 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,0824336 0,08699148 ! appendage morphogenesis GO:0035107 150 72 0,000 0,08354586 0,08812718 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,08354586 0,08808914 ! respiratory tube development GO:0030323 171 72 0,000 0,08354586 0,08805114 ! B cell activation GO:0042113 179 72 0,000 0,08354586 0,08801317 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,08354586 0,08797524 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,08354586 0,08793733 ! appendage development GO:0048736 151 73 0,000 0,08465681 0,0890683 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,08465681 0,08902996 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,08465681 0,08899165 ! regulation of immune effector process GO:0002697 156 73 0,000 0,08465681 0,08895337 ! acute inflammatory response GO:0002526 118 74 0,000 0,08576644 0,09008058 ! amino acid transport GO:0006865 148 74 0,000 0,08576644 0,09004187 ! regulation of caspase activity GO:0043281 136 74 0,000 0,08576644 0,09000319 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,08576644 0,08996454 ! respiratory system development GO:0060541 175 74 0,000 0,08576644 0,08992593 ! organelle localization GO:0051640 155 74 0,000 0,08576644 0,08988735 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,08687476 0,09100988 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,08687476 0,09097087 ! reproductive structure development GO:0048608 131 75 0,000 0,08687476 0,0909319 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,08687476 0,09089295 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,08687476 0,09085404 ! eye development GO:0001654 155 75 0,000 0,08687476 0,09081517 ! axon guidance GO:0007411 162 75 0,000 0,08687476 0,09077632 ! rhythmic process GO:0048511 142 75 0,000 0,08687476 0,09073751 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,08798177 0,09185447 ! learning or memory GO:0007611 161 76 0,000 0,08798177 0,09181523 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,08798177 0,09177603 ! regulation of blood pressure GO:0008217 134 76 0,000 0,08798177 0,09173686 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,08798177 0,09169772 ! amine catabolic process GO:0009310 136 77 0,000 0,08908746 0,09281052 ! neurotransmitter transport GO:0006836 142 77 0,000 0,08908746 0,09277096 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,08908746 0,09273143 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,08908746 0,09269194 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,08908746 0,09265248 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,08908746 0,09261305 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,08908746 0,09257366 ! regulation of catabolic process GO:0009894 173 77 0,000 0,08908746 0,0925343 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,09019185 0,0936416 ! antigen processing and presentation GO:0019882 117 78 0,000 0,09019185 0,09360182 ! fertilization GO:0009566 99 78 0,000 0,09019185 0,09356207 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,09019185 0,09352236 ! blood coagulation GO:0007596 151 79 0,000 0,09129493 0,09462601 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,09129493 0,09458588 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,09129493 0,09454578 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,09129493 0,09450572 ! protein oligomerization GO:0051259 149 79 0,000 0,09129493 0,09446569 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,09129493 0,0944257 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,0923967 0,09552481 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,0923967 0,0954844 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,0923967 0,09544403 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,0923967 0,09540369 ! meiosis GO:0007126 143 81 0,000 0,09349716 0,09649919 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,09349716 0,09645843 ! response to hypoxia GO:0001666 178 81 0,000 0,09349716 0,09641772 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,09349716 0,09637703 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,09459633 0,09746893 ! protein import into nucleus GO:0006606 174 82 0,000 0,09459633 0,09742784 ! meiotic cell cycle GO:0051321 144 82 0,000 0,09459633 0,09738678 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,09569419 0,09847553 ! exocytosis GO:0006887 153 83 0,000 0,09569419 0,09843406 ! response to drug GO:0042493 149 83 0,000 0,09569419 0,09839264 ! response to oxygen levels GO:0070482 183 83 0,000 0,09569419 0,09835124 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,09569419 0,09830988 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,09569419 0,09826856 ! nuclear import GO:0051170 177 83 0,000 0,09569419 0,09822727 ! inorganic anion transport GO:0015698 156 83 0,000 0,09569419 0,09818601 ! T cell activation GO:0042110 189 84 0,000 0,09679075 0,09926944 ! response to nutrient GO:0007584 135 84 0,000 0,09679075 0,09922778 ! digestion GO:0007586 130 84 0,000 0,09679075 0,09918616 ! hemostasis GO:0007599 165 85 0,000 0,09788601 0,10026647 ! negative regulation of transport GO:0051051 164 85 0,000 0,09788601 0,10022444 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,09788601 0,10018246 ! negative regulation of growth GO:0045926 168 85 0,000 0,09788601 0,1001405 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,09788601 0,10009859 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,09788601 0,10005671 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,09897998 0,10113261 ! regulation of lyase activity GO:0051339 169 86 0,000 0,09897998 0,10109034 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,09897998 0,10104809 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,10007265 0,10212092 ! mitochondrion organization GO:0007005 159 87 0,000 0,10007265 0,10207828 ! alcohol catabolic process GO:0046164 142 87 0,000 0,10007265 0,10203567 ! nucleosome assembly GO:0006334 126 87 0,000 0,10007265 0,1019931 ! cellular respiration GO:0045333 143 88 0,000 0,10116402 0,10306243 ! amine biosynthetic process GO:0009309 146 88 0,000 0,10116402 0,10301947 ! sensory perception of smell GO:0007608 117 88 0,000 0,10116402 0,10297654 ! chromatin assembly GO:0031497 128 88 0,000 0,10116402 0,10293365 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,10116402 0,1028908 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,1022541 0,10395621 ! regulation of DNA binding GO:0051101 167 89 0,000 0,1022541 0,10391297 ! tube morphogenesis GO:0035239 194 89 0,000 0,1022541 0,10386976 ! cellular defense response GO:0006968 123 89 0,000 0,1022541 0,10382659 ! protein localization in nucleus GO:0034504 192 89 0,000 0,1022541 0,10378345 ! regulation of neurological system process GO:0031644 175 89 0,000 0,1022541 0,10374035 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,10334289 0,10480145 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,10334289 0,10475796 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,10443039 0,10581645 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,10443039 0,10577258 ! gland development GO:0048732 220 91 0,000 0,10443039 0,10572874 ! defense response to bacterium GO:0042742 112 91 0,000 0,10443039 0,10568494 ! bone development GO:0060348 206 92 0,000 0,10551661 0,10673999 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,10551661 0,10669581 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,10551661 0,10665166 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,10660153 0,1077037 ! amine transport GO:0015837 181 93 0,000 0,10660153 0,10765917 ! vitamin metabolic process GO:0006766 153 93 0,000 0,10660153 0,10761469 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,10768517 0,10866372 ! female pregnancy GO:0007565 166 94 0,000 0,10768517 0,10861886 ! sterol metabolic process GO:0016125 166 94 0,000 0,10768517 0,10857403 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,10768517 0,10852924 ! regulation of membrane potential GO:0042391 179 94 0,000 0,10768517 0,10848448 ! regulation of defense response GO:0031347 171 95 0,000 0,10876753 0,10952971 ! nucleosome organization GO:0034728 143 95 0,000 0,10876753 0,10948458 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,10876753 0,10943949 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,10876753 0,10939443 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,10876753 0,10934941 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,10876753 0,10930443 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,10876753 0,10925949 ! sex differentiation GO:0007548 171 96 0,000 0,1098486 0,1103001 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1098486 0,11025478 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,1109284 0,11129284 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,1109284 0,11124716 ! transcription initiation GO:0006352 171 97 0,000 0,1109284 0,11120151 ! leukocyte differentiation GO:0002521 232 98 0,000 0,11200691 0,11223662 ! forebrain development GO:0030900 210 98 0,000 0,11200691 0,1121906 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,11200691 0,11214462 ! mRNA transport GO:0051028 185 100 0,000 0,11416011 0,11425364 ! positive regulation of immune response GO:0050778 175 100 0,000 0,11416011 0,11420685 ! hormone metabolic process GO:0042445 171 100 0,000 0,11416011 0,11416011