pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3799-4-real-Parker_GPL1390-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL1390.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cyclin-dependent protein kinase regulator activity GO:0016538 11 11 3,000 2,285E-10 8,161E-07 ! G2/M transition of mitotic cell cycle GO:0000086 17 17 3,000 1,642E-09 2,932E-06 ! interphase of mitotic cell cycle GO:0051329 84 82 4,000 1,356E-08 1,615E-05 GO:0051325|interphase, ! microtubule cytoskeleton organization GO:0000226 92 87 4,000 1,832E-08 1,635E-05 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 2,000 4,766E-08 3,404E-05 ! gamma-tubulin complex GO:0000930 12 10 2,000 1,02E-07 6,071E-05 ! G1/S transition of mitotic cell cycle GO:0000082 47 46 3,000 1,107E-07 5,646E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 51 50 3,000 1,558E-07 6,955E-05 ! protein kinase regulator activity GO:0019887 64 64 3,000 4,263E-07 1,691E-04 ! tubulin binding GO:0015631 70 67 3,000 5,133E-07 1,833E-04 ! kinase regulator activity GO:0019207 77 77 3,000 9,009E-07 2,925E-04 ! spindle organization GO:0007051 30 29 2,000 3,07E-06 9,136E-04 ! microtubule organizing center part GO:0044450 34 31 2,000 3,772E-06 1,036E-03 ! spindle assembly GO:0051225 5 5 1,000 9,657E-06 2,463E-03 ! induction of apoptosis by intracellular signals GO:0008629 46 43 2,000 1,028E-05 2,447E-03 ! microtubule binding GO:0008017 49 46 2,000 1,262E-05 2,817E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 1,000 1,448E-05 3,041E-03 ! flotillin complex GO:0016600 6 6 1,000 1,448E-05 2,872E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 9 6 1,000 1,448E-05 2,721E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of protein ubiquitination GO:0031398 6 6 1,000 1,448E-05 2,585E-03 ! ciliary rootlet GO:0035253 6 6 1,000 1,448E-05 2,462E-03 ! establishment of apical/basal cell polarity GO:0035089 6 6 1,000 1,448E-05 2,35E-03 ! response to UV GO:0009411 50 49 2,000 1,529E-05 2,374E-03 ! eye photoreceptor cell differentiation GO:0001754 10 7 1,000 2,026E-05 3,014E-03 GO:0042462|eye photoreceptor cell development, ! natural killer cell mediated immunity GO:0002228 7 7 1,000 2,026E-05 2,893E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! postreplication repair GO:0006301 7 7 1,000 2,026E-05 2,782E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 8 1,000 2,699E-05 3,57E-03 ! regulation of DNA repair GO:0006282 8 8 1,000 2,699E-05 3,442E-03 ! gamma-tubulin binding GO:0043015 8 8 1,000 2,699E-05 3,324E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 8 8 1,000 2,699E-05 3,213E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 9 9 1,000 3,468E-05 3,995E-03 ! photoreceptor cell development GO:0042461 12 9 1,000 3,468E-05 3,87E-03 GO:0046530|photoreceptor cell differentiation, ! microtubule bundle formation GO:0001578 9 9 1,000 3,468E-05 3,753E-03 ! leukocyte mediated cytotoxicity GO:0001909 9 9 1,000 3,468E-05 3,643E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 9 9 1,000 3,468E-05 3,539E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 9 9 1,000 3,468E-05 3,44E-03 ! positive regulation of protein modification process GO:0031401 69 65 2,000 3,59E-05 3,465E-03 ! establishment of cell polarity GO:0030010 10 10 1,000 4,333E-05 4,072E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 5,293E-05 4,846E-03 ! Golgi vesicle budding GO:0048194 11 11 1,000 5,293E-05 4,725E-03 ! negative regulation of lipid metabolic process GO:0045833 13 12 1,000 6,347E-05 5,528E-03 ! cell killing GO:0001906 12 12 1,000 6,347E-05 5,397E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 12 12 1,000 6,347E-05 5,271E-03 ! cilium part GO:0044441 12 12 1,000 6,347E-05 5,151E-03 ! regulation of protein ubiquitination GO:0031396 13 13 1,000 7,497E-05 5,949E-03 ! double-strand break repair via homologous recombination GO:0000724 13 13 1,000 7,497E-05 5,82E-03 GO:0000725|recombinational repair, ! MHC class I protein binding GO:0042288 13 13 1,000 7,497E-05 5,696E-03 ! guanylate kinase activity GO:0004385 16 14 1,000 8,741E-05 6,503E-03 ! centrosome cycle GO:0007098 14 14 1,000 8,741E-05 6,371E-03 ! protein serine/threonine kinase inhibitor activity GO:0030291 14 14 1,000 8,741E-05 6,243E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 8,741E-05 6,121E-03 ! fructose metabolic process GO:0006000 15 15 1,000 1,008E-04 6,922E-03 ! ubiquitin binding GO:0043130 15 15 1,000 1,008E-04 6,792E-03 ! kinesin complex GO:0005871 16 16 1,000 1,151E-04 7,614E-03 ! regulation of lipid biosynthetic process GO:0046890 18 17 1,000 1,304E-04 8,467E-03 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 17 1,000 1,304E-04 8,316E-03 ! membrane budding GO:0006900 18 17 1,000 1,304E-04 8,17E-03 ! nuclear ubiquitin ligase complex GO:0000152 17 17 1,000 1,304E-04 8,029E-03 ! cell-cell junction organization GO:0045216 17 17 1,000 1,304E-04 7,893E-03 ! chaperone binding GO:0051087 18 18 1,000 1,466E-04 8,727E-03 ! negative regulation of cell cycle process GO:0010948 18 18 1,000 1,466E-04 8,584E-03 ! small conjugating protein binding GO:0032182 18 18 1,000 1,466E-04 8,445E-03 ! cellular response to unfolded protein GO:0034620 21 19 1,000 1,638E-04 9,283E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! microtubule-based transport GO:0010970 19 19 1,000 1,638E-04 9,138E-03 ! MHC protein binding GO:0042287 19 19 1,000 1,638E-04 8,998E-03 ! microtubule organizing center organization GO:0031023 20 20 1,000 1,819E-04 9,84E-03 GO:0051297|centrosome organization, ! negative regulation of Wnt receptor signaling pathway GO:0030178 21 20 1,000 1,819E-04 9,693E-03 ! alditol metabolic process GO:0019400 21 20 1,000 1,819E-04 9,551E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 24 21 1,000 2,009E-04 0,01039711 ! regulation of fatty acid metabolic process GO:0019217 22 21 1,000 2,009E-04 0,01024858 ! positive regulation of fibroblast proliferation GO:0048146 22 21 1,000 2,009E-04 0,01010424 ! site of polarized growth GO:0030427 23 22 1,000 2,209E-04 0,01095384 ! positive regulation of B cell activation GO:0050871 26 22 1,000 2,209E-04 0,01080379 ! negative regulation of phosphorylation GO:0042326 26 22 1,000 2,209E-04 0,01065779 ! androgen receptor binding GO:0050681 23 23 1,000 2,417E-04 0,01151041 ! sperm motility GO:0030317 23 23 1,000 2,417E-04 0,01135896 ! negative regulation of phosphorus metabolic process GO:0010563 27 23 1,000 2,417E-04 0,01121144 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 24 23 1,000 2,417E-04 0,0110677 ! GABA receptor activity GO:0016917 24 23 1,000 2,417E-04 0,01092761 ! caveola GO:0005901 24 23 1,000 2,417E-04 0,01079101 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 24 24 1,000 2,636E-04 0,01161984 ! regulation of fibroblast proliferation GO:0048145 25 24 1,000 2,636E-04 0,01147814 ! regulation of cellular ketone metabolic process GO:0010565 26 25 1,000 2,863E-04 0,01231867 ! regulation of microtubule cytoskeleton organization GO:0070507 27 25 1,000 2,863E-04 0,01217202 ! fat cell differentiation GO:0045444 26 26 1,000 3,1E-04 0,01302356 ! nucleotide kinase activity GO:0019201 30 26 1,000 3,1E-04 0,01287212 ! response to endoplasmic reticulum stress GO:0034976 29 26 1,000 3,1E-04 0,01272417 ! cellular response to extracellular stimulus GO:0031668 27 26 1,000 3,1E-04 0,01257958 ! ER-nuclear signaling pathway GO:0006984 31 28 1,000 3,601E-04 0,01444961 ! protein kinase inhibitor activity GO:0004860 28 28 1,000 3,601E-04 0,01428906 ! glutamate receptor activity GO:0008066 33 30 1,000 4,139E-04 0,01624395 ! kinase inhibitor activity GO:0019210 30 30 1,000 4,139E-04 0,01606738 ! hexose biosynthetic process GO:0019319 32 30 1,000 4,139E-04 0,01589461 ! regulation of microtubule-based process GO:0032886 32 30 1,000 4,139E-04 0,01572552 ! meiosis I GO:0007127 31 31 1,000 4,422E-04 0,01662331 ! NAD or NADH binding GO:0051287 31 31 1,000 4,422E-04 0,01645015 ! regulation of Wnt receptor signaling pathway GO:0030111 35 32 1,000 4,714E-04 0,01735573 ! regulation of B cell activation GO:0050864 36 32 1,000 4,714E-04 0,01717863 ! establishment or maintenance of cell polarity GO:0007163 33 33 1,000 5,016E-04 0,01809157 ! protein targeting to membrane GO:0006612 35 33 1,000 5,016E-04 0,01791065 ! eye morphogenesis GO:0048592 38 33 1,000 5,016E-04 0,01773332 ! monosaccharide biosynthetic process GO:0046364 35 33 1,000 5,016E-04 0,01755946 ! cell junction organization GO:0034330 35 33 1,000 5,016E-04 0,01738898 ! steroid hormone receptor binding GO:0035258 33 33 1,000 5,016E-04 0,01722178 ! androgen receptor signaling pathway GO:0030521 34 33 1,000 5,016E-04 0,01705776 ! positive regulation of DNA metabolic process GO:0051054 40 35 1,000 5,645E-04 0,01901857 ! response to calcium ion GO:0051592 39 35 1,000 5,645E-04 0,01884082 ! polyol metabolic process GO:0019751 36 35 1,000 5,645E-04 0,01866637 ! negative regulation of adenylate cyclase activity GO:0007194 38 36 1,000 5,974E-04 0,01957156 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of leukocyte proliferation GO:0070665 40 36 1,000 5,974E-04 0,01939363 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! alcohol biosynthetic process GO:0046165 40 38 1,000 6,658E-04 0,02142067 ! positive regulation of cell cycle GO:0045787 39 39 1,000 7,014E-04 0,02236379 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 44 40 1,000 7,379E-04 0,02331879 ! response to estrogen stimulus GO:0043627 41 40 1,000 7,379E-04 0,02311424 ! regulation of gene expression, epigenetic GO:0040029 43 40 1,000 7,379E-04 0,02291325 ! double-strand break repair GO:0006302 41 41 1,000 7,753E-04 0,02386659 ! damaged DNA binding GO:0003684 42 42 1,000 8,136E-04 0,02483113 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 50 44 1,000 8,928E-04 0,02701953 ! regulation of mast cell proliferation GO:0070666 48 44 1,000 8,928E-04 0,02679247 ! regulation of leukocyte proliferation GO:0070663 50 46 1,000 9,757E-04 0,02903468 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! vesicle organization GO:0016050 50 47 1,000 1,018E-03 0,03005682 ! cell cortex part GO:0044448 51 47 1,000 1,018E-03 0,02981045 ! DNA damage response, signal transduction GO:0042770 58 52 1,000 1,246E-03 0,03616301 ! positive regulation of protein amino acid phosphorylation GO:0001934 54 52 1,000 1,246E-03 0,03587138 ! negative regulation of cytoskeleton organization GO:0051494 57 52 1,000 1,246E-03 0,03558441 ! regulation of cellular response to stress GO:0080135 57 54 1,000 1,343E-03 0,03805264 ! actin filament organization GO:0007015 59 56 1,000 1,443E-03 0,04058095 ! chromosome segregation GO:0007059 59 57 1,000 1,495E-03 0,04170353 ! positive regulation of phosphorylation GO:0042327 59 57 1,000 1,495E-03 0,04138025 ! steroid hormone receptor signaling pathway GO:0030518 58 57 1,000 1,495E-03 0,04106194 ! positive regulation of phosphorus metabolic process GO:0010562 61 58 1,000 1,547E-03 0,042179 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipid metabolic process GO:0019216 63 60 1,000 1,655E-03 0,04476964 ! lymphocyte mediated immunity GO:0002449 63 60 1,000 1,655E-03 0,04443302 ! negative regulation of protein kinase activity GO:0006469 67 61 1,000 1,71E-03 0,04556961 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 62 61 1,000 1,71E-03 0,04523206 ! cell cycle checkpoint GO:0000075 64 61 1,000 1,71E-03 0,04489947 ! negative regulation of kinase activity GO:0033673 68 62 1,000 1,766E-03 0,0460304 ! microtubule motor activity GO:0003777 67 63 1,000 1,823E-03 0,04716738 ! intracellular receptor-mediated signaling pathway GO:0030522 64 63 1,000 1,823E-03 0,04682805 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 66 64 1,000 1,88E-03 0,04796516 ! negative regulation of cell growth GO:0030308 68 65 1,000 1,939E-03 0,04910802 ! negative regulation of transferase activity GO:0051348 71 65 1,000 1,939E-03 0,04876219 ! response to metal ion GO:0010038 69 65 1,000 1,939E-03 0,04842119 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 67 65 1,000 1,939E-03 0,04808494 ! response to steroid hormone stimulus GO:0048545 69 66 1,000 1,998E-03 0,04921668 ! response to unfolded protein GO:0006986 68 66 1,000 1,998E-03 0,04887958 ! diacylglycerol binding GO:0019992 71 66 1,000 1,998E-03 0,04854706 ! negative regulation of cell size GO:0045792 70 67 1,000 2,059E-03 0,04967351 ! positive regulation of lymphocyte activation GO:0051251 72 67 1,000 2,059E-03 0,04934013 ! nuclear hormone receptor binding GO:0035257 68 67 1,000 2,059E-03 0,0490112 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 69 67 1,000 2,059E-03 0,04868662 ! ubiquitin ligase complex GO:0000151 71 67 1,000 2,059E-03 0,04836631 ! leukocyte mediated immunity GO:0002443 71 68 1,000 2,12E-03 0,04947718 ! eye development GO:0001654 74 69 1,000 2,182E-03 0,0505935 ! positive regulation of ligase activity GO:0051351 71 69 1,000 2,182E-03 0,05026709 ! response to inorganic substance GO:0010035 74 70 1,000 2,245E-03 0,05138364 ! cell cortex GO:0005938 74 70 1,000 2,245E-03 0,05105635 ! cell projection part GO:0044463 75 71 1,000 2,308E-03 0,05217308 ! meiosis GO:0007126 73 72 1,000 2,373E-03 0,05329491 GO:0051327|M phase of meiotic cell cycle, ! regulation of ubiquitin-protein ligase activity GO:0051438 74 72 1,000 2,373E-03 0,05296182 ! response to protein stimulus GO:0051789 74 72 1,000 2,373E-03 0,05263286 ! meiotic cell cycle GO:0051321 75 73 1,000 2,438E-03 0,05374984 ! negative regulation of organelle organization GO:0010639 78 73 1,000 2,438E-03 0,05342009 ! hormone receptor binding GO:0051427 75 73 1,000 2,438E-03 0,05309436 ! cellular carbohydrate catabolic process GO:0044275 75 74 1,000 2,505E-03 0,05420662 ! membrane raft GO:0045121 78 74 1,000 2,505E-03 0,05388008 ! positive regulation of cell activation GO:0050867 80 75 1,000 2,572E-03 0,05499245 GO:0002696|positive regulation of leukocyte activation, ! phosphoinositide-mediated signaling GO:0048015 79 75 1,000 2,572E-03 0,05466512 ! structural constituent of cytoskeleton GO:0005200 81 75 1,000 2,572E-03 0,05434165 ! regulation of ligase activity GO:0051340 78 76 1,000 2,64E-03 0,05544947 ! cilium GO:0005929 77 76 1,000 2,64E-03 0,0551252 ! regulation of adenylate cyclase activity GO:0045761 80 77 1,000 2,709E-03 0,05623312 ! regulation of cyclase activity GO:0031279 82 79 1,000 2,849E-03 0,05880059 ! regulation of cAMP biosynthetic process GO:0030817 82 79 1,000 2,849E-03 0,05846266 ! regulation of DNA metabolic process GO:0051052 90 80 1,000 2,92E-03 0,05958405 ! alcohol catabolic process GO:0046164 83 80 1,000 2,92E-03 0,05924551 ! regulation of cell cycle process GO:0010564 84 80 1,000 2,92E-03 0,05891079 ! negative regulation of growth GO:0045926 84 80 1,000 2,92E-03 0,05857983 ! regulation of lyase activity GO:0051339 83 80 1,000 2,92E-03 0,05825256 ! condensed chromosome GO:0000793 82 80 1,000 2,92E-03 0,05792894 ! protein kinase binding GO:0019901 89 80 1,000 2,92E-03 0,05760889 ! regulation of cAMP metabolic process GO:0030814 84 81 1,000 2,992E-03 0,0587083 ! ossification GO:0001503 85 81 1,000 2,992E-03 0,05838749 ! cellular carbohydrate biosynthetic process GO:0034637 83 81 1,000 2,992E-03 0,05807017 ! bone development GO:0060348 86 82 1,000 3,065E-03 0,05916542 ! regulation of nucleotide biosynthetic process GO:0030808 87 84 1,000 3,214E-03 0,06169857 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 85 84 1,000 3,214E-03 0,06136863 GO:0010498|proteasomal protein catabolic process, ! perinuclear region of cytoplasm GO:0048471 91 85 1,000 3,289E-03 0,06247639 ! cellular respiration GO:0045333 85 85 1,000 3,289E-03 0,06214583 ! DNA recombination GO:0006310 86 85 1,000 3,289E-03 0,06181875 ! Golgi vesicle transport GO:0048193 86 86 1,000 3,365E-03 0,06292229 ! pigment granule GO:0048770 90 86 1,000 3,365E-03 0,06259457 GO:0042470|melanosome, ! cell cycle arrest GO:0007050 92 87 1,000 3,443E-03 0,06369801 ! regulation of cyclic nucleotide metabolic process GO:0030799 90 87 1,000 3,443E-03 0,06336967 ! regulation of nucleotide metabolic process GO:0006140 93 90 1,000 3,679E-03 0,06737491 ! carbohydrate biosynthetic process GO:0016051 93 91 1,000 3,76E-03 0,06849725 ! carbohydrate catabolic process GO:0016052 95 94 1,000 4,006E-03 0,07261474 ! regulation of lymphocyte activation GO:0051249 100 95 1,000 4,09E-03 0,0737584 ! Wnt receptor signaling pathway GO:0016055 104 96 1,000 4,174E-03 0,0749052 ! microtubule associated complex GO:0005875 104 97 1,000 4,26E-03 0,07605507 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 99 98 1,000 4,346E-03 0,07720794 ! kinase binding GO:0019900 108 99 1,000 4,433E-03 0,07836373 ! protein polymerization GO:0051258 114 100 1,000 4,521E-03 0,07952239 ! tRNA transcription GO:0009304 5 5 0,000 5,081E-03 0,08893544 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 5 5 0,000 5,081E-03 0,08850161 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,081E-03 0,08807199 ! benzene and derivative metabolic process GO:0042537 5 5 0,000 5,081E-03 0,08764652 ! response to oxygen radical GO:0000305 5 5 0,000 5,081E-03 0,08722514 ! positive regulation of axon extension GO:0045773 6 5 0,000 5,081E-03 0,0868078 ! negative regulation of bone resorption GO:0045779 5 5 0,000 5,081E-03 0,08639443 ! positive regulation of lipid biosynthetic process GO:0046889 5 5 0,000 5,081E-03 0,08598497 ! regulation of interferon-beta production GO:0032648 6 5 0,000 5,081E-03 0,08557938 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! sodium-independent organic anion transmembrane transporter activity GO:0015347 6 5 0,000 5,081E-03 0,0851776 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,081E-03 0,08477958 ! negative regulation of transmembrane transport GO:0034763 5 5 0,000 5,081E-03 0,08438525 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! hypothalamus development GO:0021854 5 5 0,000 5,081E-03 0,08399458 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,081E-03 0,08360751 ! N-terminal protein lipidation GO:0006498 5 5 0,000 5,081E-03 0,08322399 ! glycolipid transport GO:0046836 5 5 0,000 5,081E-03 0,08284397 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 5 5 0,000 5,081E-03 0,08246741 ! phosphoinositide 3-kinase binding GO:0043548 5 5 0,000 5,081E-03 0,08209425 ! protein amino acid sulfation GO:0006477 5 5 0,000 5,081E-03 0,08172446 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 6 5 0,000 5,081E-03 0,08135798 ! embryonic camera-type eye development GO:0031076 7 5 0,000 5,081E-03 0,08099477 GO:0048596|embryonic camera-type eye morphogenesis, ! opioid peptide activity GO:0001515 5 5 0,000 5,081E-03 0,0806348 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,081E-03 0,08027801 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 5 5 0,000 5,081E-03 0,07992436 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 5 5 0,000 5,081E-03 0,07957381 ! elastic fiber assembly GO:0048251 5 5 0,000 5,081E-03 0,07922633 ! regulation of mitochondrial membrane permeability GO:0046902 5 5 0,000 5,081E-03 0,07888187 ! neurofilament cytoskeleton organization GO:0060052 5 5 0,000 5,081E-03 0,07854039 ! ruffle membrane GO:0032587 5 5 0,000 5,081E-03 0,07820185 ! regulation of histone modification GO:0031056 5 5 0,000 5,081E-03 0,07786622 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,081E-03 0,07753346 ! behavioral response to pain GO:0048266 5 5 0,000 5,081E-03 0,07720353 ! clathrin coat assembly GO:0048268 6 5 0,000 5,081E-03 0,0768764 ! Notch receptor processing GO:0007220 5 5 0,000 5,081E-03 0,07655202 ! cerebral cortex radially oriented cell migration GO:0021799 5 5 0,000 5,081E-03 0,07623038 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 6 5 0,000 5,081E-03 0,07591142 ! serotonin receptor signaling pathway GO:0007210 5 5 0,000 5,081E-03 0,07559512 ! oxidoreductase activity, oxidizing metal ions GO:0016722 5 5 0,000 5,081E-03 0,07528145 ! response to lipid GO:0033993 5 5 0,000 5,081E-03 0,07497037 ! cytoplasmic dynein complex GO:0005868 6 5 0,000 5,081E-03 0,07466185 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,081E-03 0,07435586 ! positive regulation of muscle cell differentiation GO:0051149 5 5 0,000 5,081E-03 0,07405237 ! smooth muscle cell differentiation GO:0051145 5 5 0,000 5,081E-03 0,07375134 ! exo-alpha-sialidase activity GO:0004308 5 5 0,000 5,081E-03 0,07345275 GO:0016997|alpha-sialidase activity, ! regulation of odontogenesis GO:0042481 5 5 0,000 5,081E-03 0,07315657 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,081E-03 0,07286277 ! formate-tetrahydrofolate ligase activity GO:0004329 5 5 0,000 5,081E-03 0,07257132 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,081E-03 0,07228219 ! ovulation from ovarian follicle GO:0001542 5 5 0,000 5,081E-03 0,07199535 ! DNA ligation during DNA repair GO:0051103 5 5 0,000 5,081E-03 0,07171079 ! 1-acylglycerophosphocholine O-acyltransferase activity GO:0047184 5 5 0,000 5,081E-03 0,07142846 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,081E-03 0,07114835 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,081E-03 0,07087043 ! microfibril GO:0001527 5 5 0,000 5,081E-03 0,07059467 GO:0043205|fibril, ! parathyroid gland development GO:0060017 5 5 0,000 5,081E-03 0,07032104 ! toxin metabolic process GO:0009404 5 5 0,000 5,081E-03 0,07004953 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,081E-03 0,06978011 ! cytokine secretion GO:0050663 5 5 0,000 5,081E-03 0,06951276 ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 5 5 0,000 5,081E-03 0,06924744 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,081E-03 0,06898414 ! skeletal myofibril assembly GO:0014866 5 5 0,000 5,081E-03 0,06872284 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 5 0,000 5,081E-03 0,06846351 ! epithelial cell proliferation GO:0050673 5 5 0,000 5,081E-03 0,06820613 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 5 5 0,000 5,081E-03 0,06795067 ! regulation of retroviral genome replication GO:0045091 5 5 0,000 5,081E-03 0,06769712 ! negative regulation of survival gene product expression GO:0008634 5 5 0,000 5,081E-03 0,06744546 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,081E-03 0,06719566 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of defense response to virus by host GO:0050691 5 5 0,000 5,081E-03 0,06694771 ! transmembrane-ephrin receptor activity GO:0005005 5 5 0,000 5,081E-03 0,06670158 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,081E-03 0,06645725 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,081E-03 0,06621471 ! glutamate catabolic process GO:0006538 6 5 0,000 5,081E-03 0,06597393 ! positive regulation of isotype switching to IgG isotypes GO:0048304 9 5 0,000 5,081E-03 0,06573489 ! microvillus organization GO:0032528 5 5 0,000 5,081E-03 0,06549758 GO:0030033|microvillus assembly, ! tyrosine catabolic process GO:0006572 5 5 0,000 5,081E-03 0,06526198 ! L-serine biosynthetic process GO:0006564 5 5 0,000 5,081E-03 0,06502806 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,081E-03 0,06479582 ! pericentriolar material GO:0000242 6 5 0,000 5,081E-03 0,06456523 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,081E-03 0,06433627 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 6 5 0,000 5,081E-03 0,06410894 ! platelet-derived growth factor alpha-receptor activity GO:0005018 5 5 0,000 5,081E-03 0,0638832 ! proton-transporting V-type ATPase, V0 domain GO:0033179 5 5 0,000 5,081E-03 0,06365905 ! fibroblast growth factor receptor activity GO:0005007 5 5 0,000 5,081E-03 0,06343647 ! protein-DNA loading ATPase activity GO:0033170 5 5 0,000 5,081E-03 0,06321543 GO:0003689|DNA clamp loader activity, ! insulin-like growth factor receptor activity GO:0005010 5 5 0,000 5,081E-03 0,06299594 ! response to tumor necrosis factor GO:0034612 6 5 0,000 5,081E-03 0,06277796 ! mRNA transcription GO:0009299 6 5 0,000 5,081E-03 0,06256148 ! response to ATP GO:0033198 5 5 0,000 5,081E-03 0,06234649 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 5 5 0,000 5,081E-03 0,06213298 ! adenosine receptor activity, G-protein coupled GO:0001609 5 5 0,000 5,081E-03 0,06192092 ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,081E-03 0,0617103 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 5 5 0,000 5,081E-03 0,06150112 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,081E-03 0,06129334 ! multivesicular body GO:0005771 5 5 0,000 5,081E-03 0,06108697 ! positive regulation of transporter activity GO:0032411 5 5 0,000 5,081E-03 0,06088198 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 5 5 0,000 5,081E-03 0,06067836 ! forebrain neuron development GO:0021884 6 5 0,000 5,081E-03 0,0604761 ! insulin-like growth factor I binding GO:0031994 5 5 0,000 5,081E-03 0,06027518 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 5 5 0,000 5,081E-03 0,06007559 ! demethylase activity GO:0032451 5 5 0,000 5,081E-03 0,05987732 ! peptidyl-histidine phosphorylation GO:0018106 5 5 0,000 5,081E-03 0,05968036 ! epithelial cell maturation GO:0002070 5 5 0,000 5,081E-03 0,05948469 ! nitric-oxide synthase regulator activity GO:0030235 5 5 0,000 5,081E-03 0,05929029 ! regulation of immunoglobulin secretion GO:0051023 5 5 0,000 5,081E-03 0,05909716 ! zymogen granule GO:0042588 5 5 0,000 5,081E-03 0,05890529 ! guanylate cyclase regulator activity GO:0030249 5 5 0,000 5,081E-03 0,05871466 GO:0010851|cyclase regulator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 6 5 0,000 5,081E-03 0,05852526 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,081E-03 0,05833707 ! early endosome to late endosome transport GO:0045022 5 5 0,000 5,081E-03 0,05815009 ! positive regulation of translational initiation GO:0045948 5 5 0,000 5,081E-03 0,05796431 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,081E-03 0,05777971 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,081E-03 0,05759628 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! semaphorin receptor activity GO:0017154 6 5 0,000 5,081E-03 0,05741402 ! proteoglycan binding GO:0043394 9 5 0,000 5,081E-03 0,0572329 ! regulation of collagen metabolic process GO:0010712 6 5 0,000 5,081E-03 0,05705292 ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 6 5 0,000 5,081E-03 0,05687407 ! zinc ion homeostasis GO:0055069 5 5 0,000 5,081E-03 0,05669634 GO:0006882|cellular zinc ion homeostasis, ! deoxyribonucleoside metabolic process GO:0009120 6 5 0,000 5,081E-03 0,05651972 ! nucleoside monophosphate catabolic process GO:0009125 5 5 0,000 5,081E-03 0,05634419 ! activated T cell proliferation GO:0050798 6 5 0,000 5,081E-03 0,05616975 ! advanced glycation end-product receptor activity GO:0050785 5 5 0,000 5,081E-03 0,05599639 ! dynein binding GO:0045502 5 5 0,000 5,081E-03 0,05582409 ! regulation of dendrite development GO:0050773 5 5 0,000 5,081E-03 0,05565285 ! cardiac muscle cell development GO:0055013 5 5 0,000 5,081E-03 0,05548266 ! anterograde axon cargo transport GO:0008089 5 5 0,000 5,081E-03 0,0553135 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,081E-03 0,05514538 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,081E-03 0,05497827 GO:0003923|GPI-anchor transamidase activity, ! lymphoid progenitor cell differentiation GO:0002320 5 5 0,000 5,081E-03 0,05481217 ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,081E-03 0,05464708 ! MutLalpha complex binding GO:0032405 6 5 0,000 5,081E-03 0,05448297 ! sphingomyelin catabolic process GO:0006685 6 5 0,000 5,081E-03 0,05431985 ! high-density lipoprotein binding GO:0008035 5 5 0,000 5,081E-03 0,0541577 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,081E-03 0,05399652 ! positive regulation of B cell differentiation GO:0045579 5 5 0,000 5,081E-03 0,05383629 ! regulation of acetylcholine secretion GO:0014056 5 5 0,000 5,081E-03 0,05367701 ! centromeric DNA binding GO:0019237 5 5 0,000 5,081E-03 0,05351867 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,081E-03 0,05336126 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,081E-03 0,05320478 ! positive T cell selection GO:0043368 9 5 0,000 5,081E-03 0,05304921 ! neural tube patterning GO:0021532 5 5 0,000 5,081E-03 0,05289455 ! amylase activity GO:0016160 5 5 0,000 5,081E-03 0,05274078 ! metaphase plate congression GO:0051310 5 5 0,000 5,081E-03 0,05258791 ! regulation of sterol transport GO:0032371 5 5 0,000 5,081E-03 0,05243592 GO:0032374|regulation of cholesterol transport, ! sympathetic nervous system development GO:0048485 5 5 0,000 5,081E-03 0,05228481 ! oxygen homeostasis GO:0032364 5 5 0,000 5,081E-03 0,05213457 ! skeletal muscle regeneration GO:0043403 5 5 0,000 5,081E-03 0,05198518 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 5 5 0,000 5,081E-03 0,05183666 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! response to tumor cell GO:0002347 5 5 0,000 5,081E-03 0,05168897 ! SAP kinase activity GO:0016909 5 5 0,000 5,081E-03 0,05154213 ! positive regulation of pseudopodium assembly GO:0031274 5 5 0,000 5,081E-03 0,05139612 GO:0031272|regulation of pseudopodium assembly, ! phosphatidylserine binding GO:0001786 5 5 0,000 5,081E-03 0,05125093 ! alpha-mannosidase activity GO:0004559 6 5 0,000 5,081E-03 0,05110656 ! alpha-glucosidase activity GO:0004558 6 5 0,000 5,081E-03 0,050963 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,081E-03 0,05082025 ! myeloid dendritic cell activation GO:0001773 5 5 0,000 5,081E-03 0,05067829 GO:0043011|myeloid dendritic cell differentiation, ! anaphase GO:0051322 5 5 0,000 5,081E-03 0,05053713 GO:0000090|mitotic anaphase, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,081E-03 0,05039675 ! ribonuclease H activity GO:0004523 5 5 0,000 5,081E-03 0,05025715 ! CARD domain binding GO:0050700 5 5 0,000 5,081E-03 0,05011831 ! regulation of muscle cell apoptosis GO:0010660 5 5 0,000 5,081E-03 0,04998025 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,081E-03 0,04984294 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 5 5 0,000 5,081E-03 0,04970638 ! negative regulation of myoblast differentiation GO:0045662 5 5 0,000 5,081E-03 0,04957057 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,081E-03 0,0494355 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,081E-03 0,04930117 ! negative regulation of macrophage differentiation GO:0045650 5 5 0,000 5,081E-03 0,04916756 ! negative regulation of osteoclast differentiation GO:0045671 5 5 0,000 5,081E-03 0,04903467 ! ceramidase activity GO:0017040 5 5 0,000 5,081E-03 0,04890251 ! negative regulation of osteoblast differentiation GO:0045668 6 5 0,000 5,081E-03 0,04877105 ! GTP-Rho binding GO:0017049 5 5 0,000 5,081E-03 0,04864029 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,081E-03 0,04851024 ! chondroitin sulfotransferase activity GO:0034481 5 5 0,000 5,081E-03 0,04838088 ! positive regulation of T-helper 2 cell differentiation GO:0045630 5 5 0,000 5,081E-03 0,04825221 ! alcohol transmembrane transporter activity GO:0015665 5 5 0,000 5,081E-03 0,04812422 GO:0015166|polyol transmembrane transporter activity, ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,081E-03 0,0479969 ! TAP complex GO:0042825 5 5 0,000 5,081E-03 0,04787026 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,081E-03 0,04774429 ! actinin binding GO:0042805 6 5 0,000 5,081E-03 0,04761897 ! secretory granule organization GO:0033363 5 5 0,000 5,081E-03 0,04749432 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 5 5 0,000 5,081E-03 0,04737031 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,081E-03 0,04724695 ! striatum development GO:0021756 5 5 0,000 5,081E-03 0,04712423 ! photoreceptor inner segment GO:0001917 5 5 0,000 5,081E-03 0,04700215 ! regulation of T cell mediated cytotoxicity GO:0001914 9 5 0,000 5,081E-03 0,0468807 ! aldehyde-lyase activity GO:0016832 5 5 0,000 5,081E-03 0,04675987 ! regulation of mitochondrial depolarization GO:0051900 5 5 0,000 5,081E-03 0,04663966 ! T cell activation during immune response GO:0002286 5 5 0,000 5,081E-03 0,04652008 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,081E-03 0,0464011 ! 1-aminocyclopropane-1-carboxylate synthase activity GO:0016847 5 5 0,000 5,081E-03 0,04628273 ! dystroglycan complex GO:0016011 6 5 0,000 5,081E-03 0,04616496 ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 5 5 0,000 5,081E-03 0,04604779 ! neural plate development GO:0001840 5 5 0,000 5,081E-03 0,04593121 ! toll-like receptor signaling pathway GO:0002224 5 5 0,000 5,081E-03 0,04581523 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,081E-03 0,04569982 ! phosphopantetheine binding GO:0031177 5 5 0,000 5,081E-03 0,045585 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,081E-03 0,04547075 ! negative regulation of actin filament bundle formation GO:0032232 8 5 0,000 5,081E-03 0,04535707 GO:0051497|negative regulation of stress fiber formation, ! organ or tissue specific immune response GO:0002251 5 5 0,000 5,081E-03 0,04524396 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,081E-03 0,04513142 ! diacylglycerol metabolic process GO:0046339 5 5 0,000 5,081E-03 0,04501943 ! cytoplasmic microtubule organization GO:0031122 5 5 0,000 5,081E-03 0,04490799 ! retina homeostasis GO:0001895 5 5 0,000 5,081E-03 0,04479711 ! release of sequestered calcium ion into cytosol GO:0051209 10 5 0,000 5,081E-03 0,04468677 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! maternal placenta development GO:0001893 5 5 0,000 5,081E-03 0,04457698 ! regulation of growth hormone secretion GO:0060123 6 5 0,000 5,081E-03 0,04446772 ! collagen type IV GO:0005587 5 5 0,000 5,081E-03 0,044359 ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,081E-03 0,0442508 ! testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045 5 5 0,000 5,081E-03 0,04414314 ! retrograde protein transport, ER to cytosol GO:0030970 5 5 0,000 5,081E-03 0,04403599 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,081E-03 0,04392937 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 5 5 0,000 5,081E-03 0,04382326 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 5 5 0,000 5,081E-03 0,04371766 ! protein amino acid prenylation GO:0018346 5 5 0,000 5,081E-03 0,04361257 ! stem cell division GO:0017145 5 5 0,000 5,081E-03 0,04350798 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,081E-03 0,0434039 ! phospholipid scrambling GO:0017121 5 5 0,000 5,081E-03 0,04330031 GO:0017128|phospholipid scramblase activity, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 5 0,000 5,081E-03 0,04319721 ! regulation of humoral immune response GO:0002920 9 5 0,000 5,081E-03 0,04309461 ! H3/H4 histone acetyltransferase activity GO:0004406 5 5 0,000 5,081E-03 0,04299249 ! regulation of interferon-alpha biosynthetic process GO:0045354 6 5 0,000 5,081E-03 0,04289085 ! negative regulation of protein ubiquitination GO:0031397 5 5 0,000 5,081E-03 0,04278969 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,081E-03 0,04268901 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 5 5 0,000 5,081E-03 0,0425888 GO:0030816|positive regulation of cAMP metabolic process, ! phagocytic vesicle GO:0045335 5 5 0,000 5,081E-03 0,04248906 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,081E-03 0,04238979 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,081E-03 0,04229098 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,081E-03 0,04219263 ! polyol transport GO:0015791 6 5 0,000 5,081E-03 0,04209473 ! cell adhesion mediated by integrin GO:0033627 6 5 0,000 5,081E-03 0,04199729 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,081E-03 0,0419003 ! glycerol-3-phosphate metabolic process GO:0006072 5 5 0,000 5,081E-03 0,04180375 ! platelet activating factor metabolic process GO:0046469 5 5 0,000 5,081E-03 0,04170765 ! cobalt ion transport GO:0006824 5 5 0,000 5,081E-03 0,04161199 ! response to zinc ion GO:0010043 5 5 0,000 5,081E-03 0,04151677 ! poly(U) RNA binding GO:0008266 5 5 0,000 5,081E-03 0,04142198 ! negative regulation of cell-cell adhesion GO:0022408 5 5 0,000 5,081E-03 0,04132763 ! adaptation of signaling pathway GO:0022401 5 5 0,000 5,081E-03 0,0412337 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! glucocorticoid receptor signaling pathway GO:0042921 5 5 0,000 5,081E-03 0,0411402 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 5 5 0,000 5,081E-03 0,04104713 ! sensory perception of bitter taste GO:0050913 5 5 0,000 5,081E-03 0,04095447 ! regulation of dopamine uptake GO:0051584 5 5 0,000 5,081E-03 0,04086223 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! opsonization GO:0008228 5 5 0,000 5,081E-03 0,0407704 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,081E-03 0,04067899 ! neuron remodeling GO:0016322 6 5 0,000 5,081E-03 0,04058799 ! neurexin binding GO:0042043 5 5 0,000 5,081E-03 0,04049739 ! sensory perception of temperature stimulus GO:0050951 5 5 0,000 5,081E-03 0,04040719 ! regulation of potassium ion transport GO:0043266 5 5 0,000 5,081E-03 0,0403174 ! low-density lipoprotein particle GO:0034362 5 5 0,000 5,081E-03 0,040228 ! chemoattractant activity GO:0042056 5 5 0,000 5,081E-03 0,040139 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 6 5 0,000 5,081E-03 0,0400504 ! lipoic acid binding GO:0031405 5 5 0,000 5,081E-03 0,03996218 ! lithium ion binding GO:0031403 6 5 0,000 5,081E-03 0,03987435 ! lipoprotein particle clearance GO:0034381 5 5 0,000 5,081E-03 0,03978691 ! grooming behavior GO:0007625 5 5 0,000 5,081E-03 0,03969985 ! sequestering of actin monomers GO:0042989 5 5 0,000 5,081E-03 0,03961316 ! cobalamin binding GO:0031419 5 5 0,000 5,081E-03 0,03952686 ! retinoic acid binding GO:0001972 5 5 0,000 5,081E-03 0,03944093 ! response to axon injury GO:0048678 5 5 0,000 5,081E-03 0,03935538 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,081E-03 0,03927019 ! regulation of activin receptor signaling pathway GO:0032925 5 5 0,000 5,081E-03 0,03918538 ! positive regulation of neurotransmitter secretion GO:0001956 5 5 0,000 5,081E-03 0,03910093 ! mitochondrial genome maintenance GO:0000002 5 5 0,000 5,081E-03 0,03901684 ! protein-lysine 6-oxidase activity GO:0004720 6 5 0,000 5,081E-03 0,03893311 ! female pronucleus GO:0001939 5 5 0,000 5,081E-03 0,03884974 ! F-actin capping protein complex GO:0008290 5 5 0,000 5,081E-03 0,03876673 ! DNA topoisomerase activity GO:0003916 5 5 0,000 5,081E-03 0,03868407 ! poly(ADP-ribose) glycohydrolase activity GO:0004649 6 5 0,000 5,081E-03 0,03860176 ! spinal cord dorsal/ventral patterning GO:0021513 5 5 0,000 5,081E-03 0,03851981 ! dorsal spinal cord development GO:0021516 5 5 0,000 5,081E-03 0,0384382 ! ceramide catabolic process GO:0046514 5 5 0,000 5,081E-03 0,03835693 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,081E-03 0,03827601 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,081E-03 0,03819543 ! regulation of oligodendrocyte differentiation GO:0048713 5 5 0,000 5,081E-03 0,03811519 ! Rap GTPase activator activity GO:0046582 5 5 0,000 5,081E-03 0,03803528 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 6 5 0,000 5,081E-03 0,03795571 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 5 5 0,000 5,081E-03 0,03787647 ! positive regulation of filopodium assembly GO:0051491 5 5 0,000 5,081E-03 0,03779756 GO:0051489|regulation of filopodium assembly, ! heart trabecula formation GO:0060347 5 5 0,000 5,081E-03 0,03771898 GO:0060343|trabecula formation, ! amine oxidase activity GO:0008131 6 5 0,000 5,081E-03 0,03764072 ! neutrophil activation GO:0042119 5 5 0,000 5,081E-03 0,03756279 ! regulation of response to food GO:0032095 5 5 0,000 5,081E-03 0,03748518 ! response to food GO:0032094 5 5 0,000 5,081E-03 0,0374079 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,081E-03 0,03733092 ! protein phosphatase 1 binding GO:0008157 5 5 0,000 5,081E-03 0,03725427 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,081E-03 0,03717793 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,081E-03 0,0371019 ! organ growth GO:0035265 7 5 0,000 5,081E-03 0,03702618 ! positive regulation of multicellular organismal metabolic process GO:0044253 6 5 0,000 5,081E-03 0,03695077 ! small-subunit processome GO:0032040 5 5 0,000 5,081E-03 0,03687567 ! UDP-glucosyltransferase activity GO:0035251 5 5 0,000 5,081E-03 0,03680087 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,081E-03 0,03672638 ! nucleoside salvage GO:0043174 7 5 0,000 5,081E-03 0,03665218 GO:0006166|purine ribonucleoside salvage, ! nucleobase transport GO:0015851 5 5 0,000 5,081E-03 0,03657829 ! GPI anchor binding GO:0034235 6 5 0,000 5,081E-03 0,03650469 ! thrombin receptor activity GO:0015057 5 5 0,000 5,081E-03 0,03643138 ! nucleotide-excision repair complex GO:0000109 6 5 0,000 5,081E-03 0,03635838 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 5 5 0,000 5,081E-03 0,03628566 ! dendritic shaft GO:0043198 5 5 0,000 5,081E-03 0,03621323 ! terminal button GO:0043195 8 5 0,000 5,081E-03 0,03614109 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,081E-03 0,03606924 GO:0016274|protein-arginine N-methyltransferase activity, ! ferrous iron binding GO:0008198 6 5 0,000 5,081E-03 0,03599768 ! eukaryotic initiation factor 4E binding GO:0008190 5 5 0,000 5,081E-03 0,03592639 ! G2/M transition checkpoint GO:0031576 5 5 0,000 5,081E-03 0,03585539 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,081E-03 0,03578467 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 5 5 0,000 5,081E-03 0,03571423 ! response to UV-C GO:0010225 5 5 0,000 5,081E-03 0,03564407 ! carbonyl reductase (NADPH) activity GO:0004090 5 5 0,000 5,081E-03 0,03557418 ! regulation of alpha-beta T cell proliferation GO:0046640 9 5 0,000 5,081E-03 0,03550456 GO:0046641|positive regulation of alpha-beta T cell proliferation, ! positive regulation of organ growth GO:0046622 5 5 0,000 5,081E-03 0,03543521 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 5 5 0,000 5,081E-03 0,03536614 ! IgE binding GO:0019863 5 5 0,000 5,081E-03 0,03529733 ! 3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 5 5 0,000 5,081E-03 0,0352288 ! monoamine transmembrane transporter activity GO:0008504 5 5 0,000 5,081E-03 0,03516052 ! response to cadmium ion GO:0046686 5 5 0,000 5,081E-03 0,03509251 ! regulation of interleukin-4 production GO:0032673 5 5 0,000 5,081E-03 0,03502477 ! hair follicle maturation GO:0048820 5 5 0,000 5,081E-03 0,03495728 ! regulation of interleukin-10 production GO:0032653 5 5 0,000 5,081E-03 0,03489006 ! ribosomal large subunit biogenesis GO:0042273 5 5 0,000 5,081E-03 0,03482309 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,081E-03 0,03475638 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,081E-03 0,03468992 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,081E-03 0,03462372 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,081E-03 0,03455777 GO:0005218|intracellular ligand-gated calcium channel activity, ! general transcriptional repressor activity GO:0016565 5 5 0,000 5,081E-03 0,03449207 ! peroxisome fission GO:0016559 5 5 0,000 5,081E-03 0,03442662 ! alpha-tubulin binding GO:0043014 5 5 0,000 5,081E-03 0,03436142 ! mitotic recombination GO:0006312 5 5 0,000 5,081E-03 0,03429646 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,081E-03 0,03423175 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,081E-03 0,03416729 ! positive regulation of chemokine production GO:0032722 5 5 0,000 5,081E-03 0,03410306 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,081E-03 0,03403908 ! muscle cell proliferation GO:0033002 5 5 0,000 5,081E-03 0,03397534 ! membrane to membrane docking GO:0022614 5 5 0,000 5,081E-03 0,03391183 ! translation activator activity GO:0008494 5 5 0,000 5,081E-03 0,03384856 ! N-formyl peptide receptor activity GO:0004982 5 5 0,000 5,081E-03 0,03378553 ! coenzyme A biosynthetic process GO:0015937 6 5 0,000 5,081E-03 0,03372273 ! histamine receptor activity GO:0004969 5 5 0,000 5,081E-03 0,03366017 ! dopamine receptor activity GO:0004952 5 5 0,000 5,081E-03 0,03359783 ! galactosidase activity GO:0015925 5 5 0,000 5,081E-03 0,03353573 ! prostaglandin E receptor activity GO:0004957 6 5 0,000 5,081E-03 0,03347386 ! cellular response to nutrient GO:0031670 5 5 0,000 5,081E-03 0,03341221 ! basic amino acid transmembrane transporter activity GO:0015174 5 5 0,000 5,081E-03 0,03335079 ! ATP-gated cation channel activity GO:0004931 7 5 0,000 5,081E-03 0,0332896 ! cytochrome-b5 reductase activity GO:0004128 5 5 0,000 5,081E-03 0,03322863 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,081E-03 0,03316788 ! glycine transmembrane transporter activity GO:0015187 5 5 0,000 5,081E-03 0,03310735 ! tyrosine phosphorylation of STAT protein GO:0007260 6 5 0,000 5,081E-03 0,03304705 ! tricarboxylic acid cycle enzyme complex GO:0045239 5 5 0,000 5,081E-03 0,03298696 ! RNA polymerase I transcription factor activity GO:0003701 5 5 0,000 5,081E-03 0,0329271 ! progesterone metabolic process GO:0042448 5 5 0,000 5,081E-03 0,03286744 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 5 5 0,000 5,081E-03 0,03280801 ! disaccharide metabolic process GO:0005984 5 5 0,000 5,081E-03 0,03274879 ! 5'-3' exonuclease activity GO:0008409 5 5 0,000 5,081E-03 0,03268978 ! type II transforming growth factor beta receptor binding GO:0005114 5 5 0,000 5,081E-03 0,03263099 ! histone acetyltransferase binding GO:0035035 5 5 0,000 5,081E-03 0,0325724 ! endosome to lysosome transport GO:0008333 5 5 0,000 5,081E-03 0,03251403 ! glial cell migration GO:0008347 5 5 0,000 5,081E-03 0,03245587 ! S-acyltransferase activity GO:0016417 5 5 0,000 5,081E-03 0,03239791 ! phosphoinositide 3-kinase regulator activity GO:0035014 5 5 0,000 5,081E-03 0,03234016 ! phosphatidylinositol-4-phosphate 3-kinase activity GO:0035005 5 5 0,000 5,081E-03 0,03228261 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,081E-03 0,03222527 ! nucleobase transmembrane transporter activity GO:0015205 5 5 0,000 5,081E-03 0,03216814 ! asparaginase activity GO:0004067 5 5 0,000 5,081E-03 0,0321112 ! insemination GO:0007320 5 5 0,000 5,081E-03 0,03205447 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,081E-03 0,03199794 ! negative regulation of smooth muscle contraction GO:0045986 6 5 0,000 5,081E-03 0,0319416 ! aminoacylase activity GO:0004046 5 5 0,000 5,081E-03 0,03188546 ! receptor biosynthetic process GO:0032800 5 5 0,000 5,081E-03 0,03182953 ! penetration of zona pellucida GO:0007341 5 5 0,000 5,081E-03 0,03177378 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 6 5 0,000 5,081E-03 0,03171823 ! aldehyde reductase activity GO:0004032 5 5 0,000 5,081E-03 0,03166288 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 5 0,000 5,081E-03 0,03160772 ! unconventional myosin complex GO:0016461 5 5 0,000 5,081E-03 0,03155275 ! carnitine metabolic process GO:0009437 5 5 0,000 5,081E-03 0,03149797 GO:0006577|betaine metabolic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 6 6 0,000 6,094E-03 0,03771413 ! regulation of helicase activity GO:0051095 6 6 0,000 6,094E-03 0,03764889 ! testosterone 17-beta-dehydrogenase activity GO:0050327 6 6 0,000 6,094E-03 0,03758386 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 6 6 0,000 6,094E-03 0,03751906 ! tumor necrosis factor-mediated signaling pathway GO:0033209 6 6 0,000 6,094E-03 0,03745449 ! negative regulation of small GTPase mediated signal transduction GO:0051058 7 6 0,000 6,094E-03 0,03739013 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 7 6 0,000 6,094E-03 0,037326 ! regulation of hormone biosynthetic process GO:0046885 6 6 0,000 6,094E-03 0,03726208 ! ephrin receptor binding GO:0046875 7 6 0,000 6,094E-03 0,03719839 ! biotin binding GO:0009374 7 6 0,000 6,094E-03 0,03713491 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,094E-03 0,03707165 ! insulin receptor substrate binding GO:0043560 7 6 0,000 6,094E-03 0,0370086 ! drug:hydrogen antiporter activity GO:0015307 6 6 0,000 6,094E-03 0,03694577 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,094E-03 0,03688315 ! carbohydrate phosphorylation GO:0046835 6 6 0,000 6,094E-03 0,03682074 ! regulation of respiratory gaseous exchange GO:0043576 6 6 0,000 6,094E-03 0,03675854 ! neuron adhesion GO:0007158 6 6 0,000 6,094E-03 0,03669655 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,094E-03 0,03663477 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 6 6 0,000 6,094E-03 0,0365732 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,094E-03 0,03651184 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 6 0,000 6,094E-03 0,03645068 ! regulation of cardiac muscle cell proliferation GO:0060043 6 6 0,000 6,094E-03 0,03638973 ! positive regulation of receptor-mediated endocytosis GO:0048260 6 6 0,000 6,094E-03 0,03632897 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 6 6 0,000 6,094E-03 0,03626843 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,094E-03 0,03620808 ! eukaryotic translation elongation factor 1 complex GO:0005853 6 6 0,000 6,094E-03 0,03614793 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,094E-03 0,03608799 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 6 6 0,000 6,094E-03 0,03602824 ! cytoplasmic microtubule GO:0005881 7 6 0,000 6,094E-03 0,03596869 ! Arp2/3 protein complex GO:0005885 7 6 0,000 6,094E-03 0,03590933 ! neurofilament GO:0005883 6 6 0,000 6,094E-03 0,03585017 ! glial cell fate commitment GO:0021781 6 6 0,000 6,094E-03 0,03579121 ! dynactin complex GO:0005869 6 6 0,000 6,094E-03 0,03573244 ! fibroblast growth factor receptor antagonist activity GO:0030353 6 6 0,000 6,094E-03 0,03567386 GO:0005104|fibroblast growth factor receptor binding, GO:0005152|interleukin-1 receptor antagonist activity, ! translation repressor activity GO:0030371 6 6 0,000 6,094E-03 0,03561548 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 6 6 0,000 6,094E-03 0,03555728 ! lipopolysaccharide binding GO:0001530 6 6 0,000 6,094E-03 0,03549928 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,094E-03 0,03544146 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,094E-03 0,03538383 ! negative regulation of viral genome replication GO:0045071 6 6 0,000 6,094E-03 0,03532639 ! traversing start control point of mitotic cell cycle GO:0007089 6 6 0,000 6,094E-03 0,03526913 ! protein lipoylation GO:0009249 6 6 0,000 6,094E-03 0,03521206 ! cysteine metabolic process GO:0006534 6 6 0,000 6,094E-03 0,03515518 ! regulation of isotype switching to IgG isotypes GO:0048302 10 6 0,000 6,094E-03 0,03509848 ! histidine catabolic process GO:0006548 6 6 0,000 6,094E-03 0,03504196 GO:0009077|histidine family amino acid catabolic process, ! centromeric heterochromatin GO:0005721 6 6 0,000 6,094E-03 0,03498562 ! mitochondrial respiratory chain complex assembly GO:0033108 6 6 0,000 6,094E-03 0,03492946 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 6 6 0,000 6,094E-03 0,03487349 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 6 6 0,000 6,094E-03 0,03481769 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 6 6 0,000 6,094E-03 0,03476207 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 6 0,000 6,094E-03 0,03470663 ! microtubule nucleation GO:0007020 6 6 0,000 6,094E-03 0,03465136 ! proline biosynthetic process GO:0006561 7 6 0,000 6,094E-03 0,03459627 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,094E-03 0,03454136 ! transforming growth factor beta receptor activity, type I GO:0005025 6 6 0,000 6,094E-03 0,03448662 ! phasic smooth muscle contraction GO:0014821 6 6 0,000 6,094E-03 0,03443205 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,094E-03 0,03437766 ! peptidoglycan metabolic process GO:0000270 6 6 0,000 6,094E-03 0,03432343 GO:0009253|peptidoglycan catabolic process, ! cerebral cortex neuron differentiation GO:0021895 6 6 0,000 6,094E-03 0,03426938 ! paraxial mesoderm development GO:0048339 6 6 0,000 6,094E-03 0,0342155 ! melanosome organization GO:0032438 6 6 0,000 6,094E-03 0,03416178 ! mitochondrial outer membrane translocase complex GO:0005742 6 6 0,000 6,094E-03 0,03410824 ! positive regulation of neuroblast proliferation GO:0002052 6 6 0,000 6,094E-03 0,03405486 ! positive regulation of vasoconstriction GO:0045907 6 6 0,000 6,094E-03 0,03400165 ! negative regulation of DNA recombination GO:0045910 6 6 0,000 6,094E-03 0,03394861 ! positive regulation of exocytosis GO:0045921 7 6 0,000 6,094E-03 0,03389573 ! protein tyrosine kinase activator activity GO:0030296 6 6 0,000 6,094E-03 0,03384301 ! positive regulation of fatty acid metabolic process GO:0045923 6 6 0,000 6,094E-03 0,03379046 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,094E-03 0,03373807 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of mitotic cell cycle GO:0045931 6 6 0,000 6,094E-03 0,03368585 ! nonhomologous end joining complex GO:0070419 6 6 0,000 6,094E-03 0,03363378 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! vinculin binding GO:0017166 6 6 0,000 6,094E-03 0,03358188 ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,094E-03 0,03353013 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,094E-03 0,03347855 ! sodium ion homeostasis GO:0055078 6 6 0,000 6,094E-03 0,03342712 ! protein heterooligomerization GO:0051291 6 6 0,000 6,094E-03 0,03337585 ! negative regulation of gliogenesis GO:0014014 6 6 0,000 6,094E-03 0,03332474 GO:0045686|negative regulation of glial cell differentiation, ! macrophage differentiation GO:0030225 8 6 0,000 6,094E-03 0,03327379 ! translation termination factor activity GO:0008079 6 6 0,000 6,094E-03 0,03322299 GO:0003747|translation release factor activity, ! centrosome duplication GO:0051298 6 6 0,000 6,094E-03 0,03317234 ! astrocyte development GO:0014002 6 6 0,000 6,094E-03 0,03312185 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,094E-03 0,03307151 ! purine base biosynthetic process GO:0009113 7 6 0,000 6,094E-03 0,03302133 ! fibrinolysis GO:0042730 7 6 0,000 6,094E-03 0,0329713 ! peptidyl-asparagine modification GO:0018196 6 6 0,000 6,094E-03 0,03292142 GO:0018279|protein amino acid N-linked glycosylation via asparagine, GO:0004579|dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ! eating behavior GO:0042755 6 6 0,000 6,094E-03 0,03287169 ! B cell lineage commitment GO:0002326 6 6 0,000 6,094E-03 0,03282211 ! thiamin and derivative metabolic process GO:0042723 6 6 0,000 6,094E-03 0,03277267 ! response to exogenous dsRNA GO:0043330 6 6 0,000 6,094E-03 0,03272339 ! enucleate erythrocyte differentiation GO:0043353 6 6 0,000 6,094E-03 0,03267426 ! melanosome transport GO:0032402 6 6 0,000 6,094E-03 0,03262527 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 6 6 0,000 6,094E-03 0,03257643 GO:0014066|regulation of phosphoinositide 3-kinase cascade, ! mast cell activation GO:0045576 6 6 0,000 6,094E-03 0,03252774 ! regulation of dopamine secretion GO:0014059 6 6 0,000 6,094E-03 0,03247919 ! regulation of protein kinase B signaling cascade GO:0051896 6 6 0,000 6,094E-03 0,03243078 ! negative regulation of focal adhesion formation GO:0051895 8 6 0,000 6,094E-03 0,03238252 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,094E-03 0,03233441 ! transcription initiation factor activity GO:0016986 6 6 0,000 6,094E-03 0,03228643 ! negative regulation of T cell differentiation GO:0045581 6 6 0,000 6,094E-03 0,0322386 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,094E-03 0,03219091 ! Schwann cell development GO:0014044 6 6 0,000 6,094E-03 0,03214336 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 6 0,000 6,094E-03 0,03209595 ! G-protein coupled photoreceptor activity GO:0008020 6 6 0,000 6,094E-03 0,03204868 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,094E-03 0,03200155 ! regulation of chondrocyte differentiation GO:0032330 6 6 0,000 6,094E-03 0,03195456 ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,094E-03 0,03190771 ! superoxide-generating NADPH oxidase activity GO:0016175 6 6 0,000 6,094E-03 0,03186099 ! nuclear envelope lumen GO:0005641 6 6 0,000 6,094E-03 0,03181441 ! RNA polymerase II transcription elongation factor activity GO:0016944 7 6 0,000 6,094E-03 0,03176796 ! regulation of meiosis GO:0040020 6 6 0,000 6,094E-03 0,03172166 GO:0051445|regulation of meiotic cell cycle, ! establishment of nucleus localization GO:0040023 8 6 0,000 6,094E-03 0,03167548 ! lipoxygenase activity GO:0016165 6 6 0,000 6,094E-03 0,03162944 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,094E-03 0,03158354 ! alpha DNA polymerase:primase complex GO:0005658 7 6 0,000 6,094E-03 0,03153776 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,094E-03 0,03149212 ! DNA replication factor C complex GO:0005663 6 6 0,000 6,094E-03 0,03144661 ! nuclear origin of replication recognition complex GO:0005664 6 6 0,000 6,094E-03 0,03140124 GO:0000808|origin recognition complex, ! DNA replication factor A complex GO:0005662 6 6 0,000 6,094E-03 0,03135599 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,094E-03 0,03131087 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,094E-03 0,03126588 ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,094E-03 0,03122103 ! chromatin silencing complex GO:0005677 6 6 0,000 6,094E-03 0,0311763 GO:0034979|NAD-dependent protein deacetylase activity, GO:0017136|NAD-dependent histone deacetylase activity, ! U12-type spliceosomal complex GO:0005689 7 6 0,000 6,094E-03 0,0311317 ! B cell homeostasis GO:0001782 7 6 0,000 6,094E-03 0,03108722 ! regulation of respiratory burst GO:0060263 6 6 0,000 6,094E-03 0,03104288 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 10 6 0,000 6,094E-03 0,03099866 GO:0002820|negative regulation of adaptive immune response, ! immunological synapse GO:0001772 6 6 0,000 6,094E-03 0,03095456 ! MutLalpha complex GO:0032389 6 6 0,000 6,094E-03 0,03091059 ! leading edge membrane GO:0031256 6 6 0,000 6,094E-03 0,03086675 ! bis(5'-adenosyl)-triphosphatase activity GO:0047710 6 6 0,000 6,094E-03 0,03082303 ! peptidyl-histidine modification GO:0018202 6 6 0,000 6,094E-03 0,03077943 ! exodeoxyribonuclease activity GO:0004529 6 6 0,000 6,094E-03 0,03073595 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! COPII vesicle coat GO:0030127 6 6 0,000 6,094E-03 0,0306926 GO:0012507|ER to Golgi transport vesicle membrane, ! peptidyl-threonine modification GO:0018210 6 6 0,000 6,094E-03 0,03064937 ! diuresis GO:0030146 6 6 0,000 6,094E-03 0,03060627 GO:0030147|natriuresis, ! definitive hemopoiesis GO:0060216 6 6 0,000 6,094E-03 0,03056328 ! glutathione biosynthetic process GO:0006750 6 6 0,000 6,094E-03 0,03052041 ! HLA-B specific inhibitory MHC class I receptor activity GO:0030109 6 6 0,000 6,094E-03 0,03047767 ! BBSome GO:0034464 6 6 0,000 6,094E-03 0,03043504 ! regulation of keratinocyte differentiation GO:0045616 6 6 0,000 6,094E-03 0,03039254 ! glycerophosphodiester phosphodiesterase activity GO:0008889 6 6 0,000 6,094E-03 0,03035015 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,094E-03 0,03030788 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,094E-03 0,03026572 ! glycolipid catabolic process GO:0019377 6 6 0,000 6,094E-03 0,03022369 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 6 6 0,000 6,094E-03 0,03018177 ! nicotinamide nucleotide biosynthetic process GO:0019359 6 6 0,000 6,094E-03 0,03013997 ! porphyrin catabolic process GO:0006787 8 6 0,000 6,094E-03 0,03009828 GO:0033015|tetrapyrrole catabolic process, ! removal of superoxide radicals GO:0019430 6 6 0,000 6,094E-03 0,03005671 ! positive regulation of glucose import GO:0046326 7 6 0,000 6,094E-03 0,03001525 GO:0010828|positive regulation of glucose transport, ! triglyceride catabolic process GO:0019433 6 6 0,000 6,094E-03 0,02997391 ! myeloid cell homeostasis GO:0002262 6 6 0,000 6,094E-03 0,02993268 ! lamin binding GO:0005521 6 6 0,000 6,094E-03 0,02989156 ! ectodermal gut morphogenesis GO:0048567 6 6 0,000 6,094E-03 0,02985056 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 6 6 0,000 6,094E-03 0,02980967 ! pattern recognition receptor signaling pathway GO:0002221 6 6 0,000 6,094E-03 0,02976889 ! negative regulation of calcium ion transport GO:0051926 6 6 0,000 6,094E-03 0,02972822 ! peroxiredoxin activity GO:0051920 6 6 0,000 6,094E-03 0,02968766 ! complement binding GO:0001848 8 6 0,000 6,094E-03 0,02964722 ! catecholamine transport GO:0051937 6 6 0,000 6,094E-03 0,02960688 ! regulation of sensory perception GO:0051931 6 6 0,000 6,094E-03 0,02956665 GO:0051930|regulation of sensory perception of pain, ! muscle adaptation GO:0043500 6 6 0,000 6,094E-03 0,02952653 ! hemopoietic progenitor cell differentiation GO:0002244 6 6 0,000 6,094E-03 0,02948653 ! dipeptidase activity GO:0016805 6 6 0,000 6,094E-03 0,02944663 ! ether hydrolase activity GO:0016803 6 6 0,000 6,094E-03 0,02940683 ! FACIT collagen GO:0005593 6 6 0,000 6,094E-03 0,02936715 ! actin filament polymerization GO:0030041 8 6 0,000 6,094E-03 0,02932757 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,094E-03 0,0292881 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 6 6 0,000 6,094E-03 0,02924873 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 6 0,000 6,094E-03 0,02920947 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,094E-03 0,02917032 ! negative regulation of synaptic transmission GO:0050805 7 6 0,000 6,094E-03 0,02913127 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,094E-03 0,02909232 ! organ regeneration GO:0031100 6 6 0,000 6,094E-03 0,02905348 ! Golgi transport complex GO:0017119 6 6 0,000 6,094E-03 0,02901474 ! sheet-forming collagen GO:0030935 6 6 0,000 6,094E-03 0,02897611 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,094E-03 0,02893757 ! positive regulation of coagulation GO:0050820 7 6 0,000 6,094E-03 0,02889914 ! defense response to Gram-negative bacterium GO:0050829 6 6 0,000 6,094E-03 0,02886082 ! positive regulation of MHC class II biosynthetic process GO:0045348 6 6 0,000 6,094E-03 0,02882259 GO:0045346|regulation of MHC class II biosynthetic process, ! thioredoxin-disulfide reductase activity GO:0004791 6 6 0,000 6,094E-03 0,02878447 ! sphingomyelin phosphodiesterase activity GO:0004767 7 6 0,000 6,094E-03 0,02874644 ! regulation of cGMP metabolic process GO:0030823 6 6 0,000 6,094E-03 0,02870852 ! myoblast cell fate commitment GO:0048625 6 6 0,000 6,094E-03 0,02867069 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,094E-03 0,02863297 ! DNA synthesis during DNA repair GO:0000731 7 6 0,000 6,094E-03 0,02859534 ! neutral lipid biosynthetic process GO:0046460 6 6 0,000 6,094E-03 0,02855782 GO:0046463|acylglycerol biosynthetic process, ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 6 6 0,000 6,094E-03 0,02852039 ! nuclear telomere cap complex GO:0000783 6 6 0,000 6,094E-03 0,02848306 GO:0000782|telomere cap complex, ! Golgi to endosome transport GO:0006895 6 6 0,000 6,094E-03 0,02844582 ! negative regulation of JAK-STAT cascade GO:0046426 7 6 0,000 6,094E-03 0,02840869 ! sterol carrier activity GO:0005498 6 6 0,000 6,094E-03 0,02837165 ! positive regulation of cell-cell adhesion GO:0022409 6 6 0,000 6,094E-03 0,02833471 ! succinate metabolic process GO:0006105 6 6 0,000 6,094E-03 0,02829786 ! myelin sheath GO:0043209 6 6 0,000 6,094E-03 0,02826111 ! perikaryon GO:0043204 7 6 0,000 6,094E-03 0,02822446 ! oxaloacetate metabolic process GO:0006107 7 6 0,000 6,094E-03 0,0281879 ! malate metabolic process GO:0006108 6 6 0,000 6,094E-03 0,02815143 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 6 6 0,000 6,094E-03 0,02811506 ! posttranscriptional gene silencing by RNA GO:0035194 6 6 0,000 6,094E-03 0,02807878 GO:0016441|posttranscriptional gene silencing, ! mating behavior GO:0007617 6 6 0,000 6,094E-03 0,0280426 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,094E-03 0,02800651 ! rhythmic behavior GO:0007622 7 6 0,000 6,094E-03 0,02797051 ! copulation GO:0007620 6 6 0,000 6,094E-03 0,0279346 ! erythrocyte maturation GO:0043249 6 6 0,000 6,094E-03 0,02789879 ! equilibrioception GO:0050957 6 6 0,000 6,094E-03 0,02786307 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,094E-03 0,02782744 ! G-protein coupled receptor kinase activity GO:0004703 6 6 0,000 6,094E-03 0,0277919 ! chemosensory behavior GO:0007635 6 6 0,000 6,094E-03 0,02775645 ! synaptic transmission, dopaminergic GO:0001963 7 6 0,000 6,094E-03 0,02772109 ! mechanosensory behavior GO:0007638 6 6 0,000 6,094E-03 0,02768582 ! response to interferon-gamma GO:0034341 6 6 0,000 6,094E-03 0,02765064 ! spinal cord patterning GO:0021511 6 6 0,000 6,094E-03 0,02761555 ! cGMP-mediated signaling GO:0019934 6 6 0,000 6,094E-03 0,02758055 ! protein geranylgeranyltransferase activity GO:0004661 6 6 0,000 6,094E-03 0,02754564 ! activation of MAPKKK activity GO:0000185 6 6 0,000 6,094E-03 0,02751082 ! nerve growth factor receptor signaling pathway GO:0048011 8 6 0,000 6,094E-03 0,02747608 ! glucosyltransferase activity GO:0046527 6 6 0,000 6,094E-03 0,02744143 ! sphingoid catabolic process GO:0046521 6 6 0,000 6,094E-03 0,02740687 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,094E-03 0,0273724 ! activin receptor activity GO:0017002 6 6 0,000 6,094E-03 0,02733801 ! ovulation GO:0030728 6 6 0,000 6,094E-03 0,02730371 ! dopamine binding GO:0035240 7 6 0,000 6,094E-03 0,02726949 ! hyperosmotic response GO:0006972 6 6 0,000 6,094E-03 0,02723536 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 6 6 0,000 6,094E-03 0,02720132 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 6 0,000 6,094E-03 0,02716736 ! nuclear localization sequence binding GO:0008139 6 6 0,000 6,094E-03 0,02713349 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,094E-03 0,0270997 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,094E-03 0,02706599 ! copper ion transmembrane transporter activity GO:0005375 6 6 0,000 6,094E-03 0,02703237 ! poly(A) RNA binding GO:0008143 6 6 0,000 6,094E-03 0,02699883 ! positive transcription elongation factor activity GO:0008159 6 6 0,000 6,094E-03 0,02696537 ! regulation of glycogen metabolic process GO:0070873 7 6 0,000 6,094E-03 0,026932 GO:0032881|regulation of polysaccharide metabolic process, ! maintenance of protein location in nucleus GO:0051457 6 6 0,000 6,094E-03 0,02689871 ! intracellular pH reduction GO:0051452 6 6 0,000 6,094E-03 0,0268655 GO:0045851|pH reduction, ! purine salvage GO:0043101 8 6 0,000 6,094E-03 0,02683237 ! nucleotide-sugar transmembrane transporter activity GO:0005338 6 6 0,000 6,094E-03 0,02679933 ! neurotrophin binding GO:0043121 6 6 0,000 6,094E-03 0,02676637 ! neurotransmitter catabolic process GO:0042135 10 6 0,000 6,094E-03 0,02673348 ! ruffle organization GO:0031529 6 6 0,000 6,094E-03 0,02670068 ! T cell mediated immunity GO:0002456 6 6 0,000 6,094E-03 0,02666796 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 7 6 0,000 6,094E-03 0,02663532 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! carnitine transport GO:0015879 6 6 0,000 6,094E-03 0,02660276 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,094E-03 0,02657028 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! palmitoyl-CoA hydrolase activity GO:0016290 6 6 0,000 6,094E-03 0,02653787 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,094E-03 0,02650555 ! phospholipase D activity GO:0004630 6 6 0,000 6,094E-03 0,0264733 ! rRNA modification GO:0000154 6 6 0,000 6,094E-03 0,02644114 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,094E-03 0,02640905 ! neuronal ion channel clustering GO:0045161 6 6 0,000 6,094E-03 0,02637704 ! response to UV-B GO:0010224 6 6 0,000 6,094E-03 0,0263451 ! interaction with symbiont GO:0051702 6 6 0,000 6,094E-03 0,02631325 ! negative regulation of insulin receptor signaling pathway GO:0046627 6 6 0,000 6,094E-03 0,02628147 ! IgG binding GO:0019864 6 6 0,000 6,094E-03 0,02624977 ! positive regulation of cytokine production during immune response GO:0002720 6 6 0,000 6,094E-03 0,02621814 ! base-excision repair, AP site formation GO:0006285 6 6 0,000 6,094E-03 0,02618659 ! benzodiazepine receptor activity GO:0008503 6 6 0,000 6,094E-03 0,02615512 ! response to copper ion GO:0046688 6 6 0,000 6,094E-03 0,02612372 ! DNA topological change GO:0006265 6 6 0,000 6,094E-03 0,02609239 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,094E-03 0,02606114 ! dendrite morphogenesis GO:0048813 6 6 0,000 6,094E-03 0,02602997 ! regulation of interleukin-1 beta production GO:0032651 6 6 0,000 6,094E-03 0,02599887 ! regulation of myeloid cell apoptosis GO:0033032 6 6 0,000 6,094E-03 0,02596785 ! positive regulation of tumor necrosis factor production GO:0032760 6 6 0,000 6,094E-03 0,0259369 ! nucleosome disassembly GO:0006337 6 6 0,000 6,094E-03 0,02590602 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! inositol trisphosphate 3-kinase activity GO:0008440 6 6 0,000 6,094E-03 0,02587522 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,094E-03 0,02584448 ! guanylyltransferase activity GO:0070568 6 6 0,000 6,094E-03 0,02581383 ! receptor internalization GO:0031623 7 6 0,000 6,094E-03 0,02578324 ! neuropeptide Y receptor activity GO:0004983 6 6 0,000 6,094E-03 0,02575273 ! ATP-dependent peptidase activity GO:0004176 6 6 0,000 6,094E-03 0,02572229 ! serine-type carboxypeptidase activity GO:0004185 6 6 0,000 6,094E-03 0,02569192 GO:0070008|serine-type exopeptidase activity, ! protein deubiquitination GO:0016579 6 6 0,000 6,094E-03 0,02566162 ! negative regulation of neuroblast proliferation GO:0007406 6 6 0,000 6,094E-03 0,0256314 ! NuRD complex GO:0016581 6 6 0,000 6,094E-03 0,02560124 ! nucleosome positioning GO:0016584 6 6 0,000 6,094E-03 0,02557116 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,094E-03 0,02554115 ! alpha-adrenergic receptor activity GO:0004936 8 6 0,000 6,094E-03 0,0255112 ! glycine binding GO:0016594 8 6 0,000 6,094E-03 0,02548133 ! costamere GO:0043034 7 6 0,000 6,094E-03 0,02545153 ! A band GO:0031672 6 6 0,000 6,094E-03 0,02542179 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,094E-03 0,02539213 ! dopamine biosynthetic process GO:0042416 7 6 0,000 6,094E-03 0,02536254 ! procollagen-proline dioxygenase activity GO:0019798 6 6 0,000 6,094E-03 0,02533301 ! negative regulation of axon extension GO:0030517 6 6 0,000 6,094E-03 0,02530355 ! actin monomer binding GO:0003785 6 6 0,000 6,094E-03 0,02527416 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,094E-03 0,02524484 ! lysozyme activity GO:0003796 6 6 0,000 6,094E-03 0,02521559 ! regulation of Rac protein signal transduction GO:0035020 6 6 0,000 6,094E-03 0,02518641 ! ATP catabolic process GO:0006200 6 6 0,000 6,094E-03 0,02515729 ! determination of adult lifespan GO:0008340 6 6 0,000 6,094E-03 0,02512824 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,094E-03 0,02509926 ! negative regulation of organic acid transport GO:0032891 6 6 0,000 6,094E-03 0,02507034 ! calcium-dependent phospholipase A2 activity GO:0047498 6 6 0,000 6,094E-03 0,02504149 ! O-acetyltransferase activity GO:0016413 6 6 0,000 6,094E-03 0,02501271 ! CoA-ligase activity GO:0016405 6 6 0,000 6,094E-03 0,02498399 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,094E-03 0,02495534 ! IkappaB kinase complex GO:0008385 6 6 0,000 6,094E-03 0,02492675 ! pyrimidine nucleotide catabolic process GO:0006244 6 6 0,000 6,094E-03 0,02489823 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,094E-03 0,02486978 ! aminomethyltransferase activity GO:0004047 6 6 0,000 6,094E-03 0,02484139 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 6 6 0,000 6,094E-03 0,02481306 ! alkaline phosphatase activity GO:0004035 6 6 0,000 6,094E-03 0,0247848 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 6 6 0,000 6,094E-03 0,02475661 ! oligosaccharide biosynthetic process GO:0009312 7 7 0,000 7,106E-03 0,02883619 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,106E-03 0,02880345 ! sleep GO:0030431 7 7 0,000 7,106E-03 0,0287708 ! synaptonemal complex assembly GO:0007130 7 7 0,000 7,106E-03 0,02873821 GO:0070193|synaptonemal complex organization, ! forebrain regionalization GO:0021871 7 7 0,000 7,106E-03 0,0287057 ! cell proliferation in forebrain GO:0021846 7 7 0,000 7,106E-03 0,02867327 ! proteasome regulatory particle GO:0005838 8 7 0,000 7,106E-03 0,02864091 ! meiotic prophase I GO:0007128 7 7 0,000 7,106E-03 0,02860862 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 7 0,000 7,106E-03 0,0285764 ! SMAD protein nuclear translocation GO:0007184 8 7 0,000 7,106E-03 0,02854426 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 7 7 0,000 7,106E-03 0,02851218 ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,106E-03 0,02848018 ! diphosphotransferase activity GO:0016778 8 7 0,000 7,106E-03 0,02844825 ! actin-myosin filament sliding GO:0033275 7 7 0,000 7,106E-03 0,0284164 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! signal peptide processing GO:0006465 7 7 0,000 7,106E-03 0,02838461 ! glycine hydroxymethyltransferase activity GO:0004372 8 7 0,000 7,106E-03 0,0283529 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,106E-03 0,02832125 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,106E-03 0,02828968 ! cerebral cortex cell migration GO:0021795 7 7 0,000 7,106E-03 0,02825818 ! tachykinin receptor signaling pathway GO:0007217 7 7 0,000 7,106E-03 0,02822674 ! membrane hyperpolarization GO:0060081 7 7 0,000 7,106E-03 0,02819538 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,106E-03 0,02816409 ! enoyl-CoA hydratase activity GO:0004300 7 7 0,000 7,106E-03 0,02813286 ! DNA replication origin binding GO:0003688 7 7 0,000 7,106E-03 0,02810171 ! ATPase binding GO:0051117 7 7 0,000 7,106E-03 0,02807062 ! positive regulation of glycolysis GO:0045821 7 7 0,000 7,106E-03 0,02803961 ! positive regulation of isotype switching GO:0045830 11 7 0,000 7,106E-03 0,02800866 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 8 7 0,000 7,106E-03 0,02797778 ! ribonucleoside triphosphate catabolic process GO:0009203 7 7 0,000 7,106E-03 0,02794696 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! protein-cofactor linkage GO:0018065 7 7 0,000 7,106E-03 0,02791622 ! positive regulation of chemokine biosynthetic process GO:0045080 7 7 0,000 7,106E-03 0,02788554 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 7 7 0,000 7,106E-03 0,02785493 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! thymic T cell selection GO:0045061 11 7 0,000 7,106E-03 0,02782439 ! structural constituent of tooth enamel GO:0030345 7 7 0,000 7,106E-03 0,02779391 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,106E-03 0,0277635 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,106E-03 0,02773316 ! activation of caspase activity by cytochrome c GO:0008635 7 7 0,000 7,106E-03 0,02770289 ! glycine catabolic process GO:0006546 7 7 0,000 7,106E-03 0,02767267 GO:0009071|serine family amino acid catabolic process, ! deoxyribonucleotide biosynthetic process GO:0009263 8 7 0,000 7,106E-03 0,02764253 ! cytoskeletal anchoring at plasma membrane GO:0007016 8 7 0,000 7,106E-03 0,02761245 ! response to pH GO:0009268 7 7 0,000 7,106E-03 0,02758244 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,106E-03 0,02755249 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! polyamine biosynthetic process GO:0006596 7 7 0,000 7,106E-03 0,02752261 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 7 7 0,000 7,106E-03 0,02749279 ! endosome organization GO:0007032 7 7 0,000 7,106E-03 0,02746303 ! thyroid hormone generation GO:0006590 7 7 0,000 7,106E-03 0,02743334 ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,106E-03 0,02740372 GO:0021940|positive regulation of granule cell precursor proliferation, ! reverse cholesterol transport GO:0043691 7 7 0,000 7,106E-03 0,02737416 ! tumor necrosis factor receptor activity GO:0005031 7 7 0,000 7,106E-03 0,02734466 ! indolalkylamine metabolic process GO:0006586 7 7 0,000 7,106E-03 0,02731522 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! proton-transporting V-type ATPase, V1 domain GO:0033180 7 7 0,000 7,106E-03 0,02728585 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,106E-03 0,02725654 ! retinoid X receptor binding GO:0046965 7 7 0,000 7,106E-03 0,0272273 ! central nervous system neuron axonogenesis GO:0021955 7 7 0,000 7,106E-03 0,02719812 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,106E-03 0,027169 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! regulation of phosphoprotein phosphatase activity GO:0043666 7 7 0,000 7,106E-03 0,02713994 GO:0010921|regulation of phosphatase activity, ! platelet-derived growth factor receptor activity GO:0005017 7 7 0,000 7,106E-03 0,02711094 ! urea metabolic process GO:0019627 7 7 0,000 7,106E-03 0,02708201 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! retinoic acid receptor signaling pathway GO:0048384 7 7 0,000 7,106E-03 0,02705314 ! regulation of type I interferon production GO:0032479 8 7 0,000 7,106E-03 0,02702433 ! peroxisomal matrix GO:0005782 7 7 0,000 7,106E-03 0,02699558 GO:0031907|microbody lumen, ! methyltransferase complex GO:0034708 7 7 0,000 7,106E-03 0,02696689 GO:0035097|histone methyltransferase complex, ! response to dietary excess GO:0002021 7 7 0,000 7,106E-03 0,02693826 ! p53 binding GO:0002039 7 7 0,000 7,106E-03 0,0269097 ! osteoblast development GO:0002076 8 7 0,000 7,106E-03 0,02688119 ! positive regulation of nitric-oxide synthase activity GO:0051000 7 7 0,000 7,106E-03 0,02685274 ! lipid phosphatase activity GO:0042577 7 7 0,000 7,106E-03 0,02682436 ! male sex determination GO:0030238 7 7 0,000 7,106E-03 0,02679603 ! clathrin binding GO:0030276 8 7 0,000 7,106E-03 0,02676777 ! negative regulation of translational initiation GO:0045947 7 7 0,000 7,106E-03 0,02673956 ! determination of anterior/posterior axis, embryo GO:0008595 7 7 0,000 7,106E-03 0,02671141 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 7 7 0,000 7,106E-03 0,02668333 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 7,106E-03 0,0266553 GO:0030204|chondroitin sulfate metabolic process, ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,106E-03 0,02662733 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,106E-03 0,02659942 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,106E-03 0,02657156 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,106E-03 0,02654377 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 8 7 0,000 7,106E-03 0,02651603 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,106E-03 0,02648835 ! protein retention in ER lumen GO:0006621 7 7 0,000 7,106E-03 0,02646073 ! cardiac muscle cell differentiation GO:0055007 7 7 0,000 7,106E-03 0,02643317 ! peptidyl-arginine modification GO:0018195 7 7 0,000 7,106E-03 0,02640566 ! regulation of circadian rhythm GO:0042752 7 7 0,000 7,106E-03 0,02637822 ! Hsp90 protein binding GO:0051879 7 7 0,000 7,106E-03 0,02635082 ! MutSalpha complex binding GO:0032407 8 7 0,000 7,106E-03 0,02632349 ! regulation of fat cell differentiation GO:0045598 7 7 0,000 7,106E-03 0,02629621 ! establishment of melanosome localization GO:0032401 7 7 0,000 7,106E-03 0,02626899 ! regulation of focal adhesion formation GO:0051893 9 7 0,000 7,106E-03 0,02624182 ! gas homeostasis GO:0033483 7 7 0,000 7,106E-03 0,02621471 ! cranial nerve morphogenesis GO:0021602 7 7 0,000 7,106E-03 0,02618766 ! subpallium development GO:0021544 7 7 0,000 7,106E-03 0,02616066 ! laminin-1 complex GO:0005606 7 7 0,000 7,106E-03 0,02613372 GO:0043256|laminin complex, ! molybdopterin cofactor biosynthetic process GO:0032324 7 7 0,000 7,106E-03 0,02610683 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! cell differentiation in hindbrain GO:0021533 8 7 0,000 7,106E-03 0,02608 ! T cell lineage commitment GO:0002360 7 7 0,000 7,106E-03 0,02605323 ! positive regulation of immunoglobulin mediated immune response GO:0002891 11 7 0,000 7,106E-03 0,02602651 GO:0002714|positive regulation of B cell mediated immunity, ! protein sumoylation GO:0016925 7 7 0,000 7,106E-03 0,02599984 ! establishment of chromosome localization GO:0051303 7 7 0,000 7,106E-03 0,02597323 GO:0050000|chromosome localization, ! regulation of lipid transport GO:0032368 7 7 0,000 7,106E-03 0,02594667 ! regulation of cell division GO:0051302 7 7 0,000 7,106E-03 0,02592017 ! chromatin assembly complex GO:0005678 7 7 0,000 7,106E-03 0,02589372 ! sex chromatin GO:0001739 7 7 0,000 7,106E-03 0,02586732 GO:0000803|sex chromosome, ! oligosaccharyl transferase activity GO:0004576 7 7 0,000 7,106E-03 0,02584098 ! chitinase activity GO:0004568 7 7 0,000 7,106E-03 0,02581469 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 7 7 0,000 7,106E-03 0,02578846 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 7 7 0,000 7,106E-03 0,02576228 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 10 7 0,000 7,106E-03 0,02573615 ! inhibitory MHC class I receptor activity GO:0032396 7 7 0,000 7,106E-03 0,02571007 GO:0030110|HLA-C specific inhibitory MHC class I receptor activity, ! ER to Golgi transport vesicle GO:0030134 7 7 0,000 7,106E-03 0,02568405 ! molybdenum ion binding GO:0030151 7 7 0,000 7,106E-03 0,02565808 ! centriolar satellite GO:0034451 8 7 0,000 7,106E-03 0,02563216 ! positive regulation of epidermis development GO:0045684 7 7 0,000 7,106E-03 0,0256063 ! proteasome regulator activity GO:0010860 7 7 0,000 7,106E-03 0,02558049 ! antibiotic transport GO:0042891 7 7 0,000 7,106E-03 0,02555473 ! negative regulation of transmission of nerve impulse GO:0051970 8 7 0,000 7,106E-03 0,02552902 ! regulation of synaptic transmission, glutamatergic GO:0051966 7 7 0,000 7,106E-03 0,02550336 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,106E-03 0,02547775 ! aspartate family amino acid catabolic process GO:0009068 7 7 0,000 7,106E-03 0,0254522 ! Wnt receptor activity GO:0042813 7 7 0,000 7,106E-03 0,0254267 ! regulation of protein homodimerization activity GO:0043496 7 7 0,000 7,106E-03 0,02540124 ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 7 7 0,000 7,106E-03 0,02537584 ! positive regulation of viral reproduction GO:0048524 7 7 0,000 7,106E-03 0,02535049 ! negative regulation of viral reproduction GO:0048525 7 7 0,000 7,106E-03 0,02532519 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 9 7 0,000 7,106E-03 0,02529994 ! blastocyst growth GO:0001832 7 7 0,000 7,106E-03 0,02527474 ! pigment granule transport GO:0051904 7 7 0,000 7,106E-03 0,02524959 ! lymphocyte activation during immune response GO:0002285 7 7 0,000 7,106E-03 0,0252245 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,106E-03 0,02519945 ! negative regulation of fibrinolysis GO:0051918 7 7 0,000 7,106E-03 0,02517445 ! negative regulation of telomere maintenance GO:0032205 7 7 0,000 7,106E-03 0,0251495 ! cerebellar cortex formation GO:0021697 8 7 0,000 7,106E-03 0,0251246 ! activation of innate immune response GO:0002218 7 7 0,000 7,106E-03 0,02509975 GO:0002758|innate immune response-activating signal transduction, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 7 7 0,000 7,106E-03 0,02507494 ! regulation of synaptic transmission, dopaminergic GO:0032225 7 7 0,000 7,106E-03 0,02505019 ! regulation of synaptic transmission, GABAergic GO:0032228 7 7 0,000 7,106E-03 0,02502549 ! flavin-containing monooxygenase activity GO:0004499 7 7 0,000 7,106E-03 0,02500083 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,106E-03 0,02497622 ! sequestering of metal ion GO:0051238 7 7 0,000 7,106E-03 0,02495166 ! regulation of T cell receptor signaling pathway GO:0050856 8 7 0,000 7,106E-03 0,02492715 ! membrane attack complex GO:0005579 7 7 0,000 7,106E-03 0,02490269 ! fibrinogen complex GO:0005577 7 7 0,000 7,106E-03 0,02487828 ! septin complex GO:0031105 9 7 0,000 7,106E-03 0,02485391 GO:0032156|septin cytoskeleton, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 7 7 0,000 7,106E-03 0,02482959 ! positive regulation of microtubule polymerization GO:0031116 7 7 0,000 7,106E-03 0,02480532 ! cellular anion homeostasis GO:0030002 7 7 0,000 7,106E-03 0,0247811 GO:0055081|anion homeostasis, ! positive regulation of cyclic nucleotide metabolic process GO:0030801 7 7 0,000 7,106E-03 0,02475692 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! behavioral response to cocaine GO:0048148 9 7 0,000 7,106E-03 0,02473279 ! autophagic vacuole formation GO:0000045 8 7 0,000 7,106E-03 0,02470871 ! negative regulation of smooth muscle cell proliferation GO:0048662 7 7 0,000 7,106E-03 0,02468467 ! translation initiation factor binding GO:0031369 7 7 0,000 7,106E-03 0,02466068 ! regulation of lipid catabolic process GO:0050994 7 7 0,000 7,106E-03 0,02463674 ! activin binding GO:0048185 7 7 0,000 7,106E-03 0,02461284 ! syncytium formation by plasma membrane fusion GO:0000768 7 7 0,000 7,106E-03 0,024589 GO:0007520|myoblast fusion, ! nucleotide-excision repair, DNA incision GO:0033683 7 7 0,000 7,106E-03 0,02456519 ! oligosaccharyltransferase complex GO:0008250 7 7 0,000 7,106E-03 0,02454143 ! phototransduction, visible light GO:0007603 7 7 0,000 7,106E-03 0,02451772 ! positive regulation of neurotransmitter transport GO:0051590 7 7 0,000 7,106E-03 0,02449406 ! lipoprotein transport GO:0042953 7 7 0,000 7,106E-03 0,02447044 ! cell division site part GO:0032155 7 7 0,000 7,106E-03 0,02444686 GO:0032153|cell division site, ! laminin binding GO:0043236 9 7 0,000 7,106E-03 0,02442333 ! detection of mechanical stimulus involved in sensory perception GO:0050974 7 7 0,000 7,106E-03 0,02439985 ! phospholipid efflux GO:0033700 7 7 0,000 7,106E-03 0,02437641 ! DNA insertion or deletion binding GO:0032135 7 7 0,000 7,106E-03 0,02435302 GO:0032138|single base insertion or deletion binding, ! glucocorticoid metabolic process GO:0008211 7 7 0,000 7,106E-03 0,02432967 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 7 7 0,000 7,106E-03 0,02430636 ! poly-purine tract binding GO:0070717 7 7 0,000 7,106E-03 0,0242831 ! T-helper 1 type immune response GO:0042088 7 7 0,000 7,106E-03 0,02425989 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,106E-03 0,02423672 GO:0032107|regulation of response to nutrient levels, ! amyloid precursor protein catabolic process GO:0042987 7 7 0,000 7,106E-03 0,02421359 ! leukocyte degranulation GO:0043299 7 7 0,000 7,106E-03 0,02419051 ! sodium:phosphate symporter activity GO:0005436 7 7 0,000 7,106E-03 0,02416747 ! bile acid and bile salt transport GO:0015721 7 7 0,000 7,106E-03 0,02414447 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,106E-03 0,02412152 ! glycerol ether biosynthetic process GO:0046504 7 7 0,000 7,106E-03 0,02409862 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,106E-03 0,02407575 GO:0046513|ceramide biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 7,106E-03 0,02405293 ! pigment granule organization GO:0048753 7 7 0,000 7,106E-03 0,02403015 ! eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 7 7 0,000 7,106E-03 0,02400742 ! regulation of interleukin-8 biosynthetic process GO:0045414 8 7 0,000 7,106E-03 0,02398473 ! regulation of pigmentation during development GO:0048070 10 7 0,000 7,106E-03 0,02396208 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 7 7 0,000 7,106E-03 0,02393947 ! macrophage activation GO:0042116 7 7 0,000 7,106E-03 0,02391691 ! positive regulation of activated T cell proliferation GO:0042104 7 7 0,000 7,106E-03 0,02389439 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 7 7 0,000 7,106E-03 0,02387191 ! galactose metabolic process GO:0006012 7 7 0,000 7,106E-03 0,02384948 ! vesicle fusion GO:0006906 7 7 0,000 7,106E-03 0,02382708 ! positive regulation of insulin secretion GO:0032024 7 7 0,000 7,106E-03 0,02380473 ! glycerol ether catabolic process GO:0044269 7 7 0,000 7,106E-03 0,02378242 GO:0046464|acylglycerol catabolic process, ! virus-infected cell apoptosis GO:0006926 7 7 0,000 7,106E-03 0,02376015 ! NuA4 histone acetyltransferase complex GO:0035267 8 7 0,000 7,106E-03 0,02373793 ! nucleoside transmembrane transporter activity GO:0005337 7 7 0,000 7,106E-03 0,02371574 GO:0015858|nucleoside transport, ! regulation of vascular permeability GO:0043114 7 7 0,000 7,106E-03 0,0236936 ! regulation of multicellular organismal metabolic process GO:0044246 8 7 0,000 7,106E-03 0,0236715 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,106E-03 0,02364943 ! peptidyl-proline dioxygenase activity GO:0031543 7 7 0,000 7,106E-03 0,02362741 ! inclusion body GO:0016234 7 7 0,000 7,106E-03 0,02360544 ! parturition GO:0007567 7 7 0,000 7,106E-03 0,0235835 ! tRNA methyltransferase activity GO:0008175 7 7 0,000 7,106E-03 0,0235616 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 7 7 0,000 7,106E-03 0,02353974 ! intercalated disc GO:0014704 8 7 0,000 7,106E-03 0,02351793 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,106E-03 0,02349615 ! neural nucleus development GO:0048857 7 7 0,000 7,106E-03 0,02347442 ! intermediate filament organization GO:0045109 8 7 0,000 7,106E-03 0,02345272 ! skeletal muscle contraction GO:0003009 7 7 0,000 7,106E-03 0,02343106 ! response to antibiotic GO:0046677 7 7 0,000 7,106E-03 0,02340945 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 7 7 0,000 7,106E-03 0,02338787 ! preribosome GO:0030684 7 7 0,000 7,106E-03 0,02336634 ! positive regulation of production of molecular mediator of immune response GO:0002702 7 7 0,000 7,106E-03 0,02334484 ! hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 7 7 0,000 7,106E-03 0,02332339 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 7 7 0,000 7,106E-03 0,02330197 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,106E-03 0,02328059 ! regulation of interleukin-1 production GO:0032652 7 7 0,000 7,106E-03 0,02325925 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,106E-03 0,02323795 ! gap junction channel activity GO:0005243 7 7 0,000 7,106E-03 0,02321669 ! transcription from RNA polymerase I promoter GO:0006360 7 7 0,000 7,106E-03 0,02319547 ! mitochondrion morphogenesis GO:0070584 8 7 0,000 7,106E-03 0,02317429 ! transcription termination GO:0006353 8 7 0,000 7,106E-03 0,02315314 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 7 7 0,000 7,106E-03 0,02313204 ! tetracycline transporter activity GO:0008493 7 7 0,000 7,106E-03 0,02311097 GO:0042895|antibiotic transporter activity, ! cytidylyltransferase activity GO:0070567 7 7 0,000 7,106E-03 0,02308994 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,106E-03 0,02306895 ! melanocortin receptor activity GO:0004977 7 7 0,000 7,106E-03 0,023048 ! coenzyme A metabolic process GO:0015936 8 7 0,000 7,106E-03 0,02302708 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 7 0,000 7,106E-03 0,0230062 ! regulation of macrophage activation GO:0043030 7 7 0,000 7,106E-03 0,02298537 ! cytidine deaminase activity GO:0004126 7 7 0,000 7,106E-03 0,02296456 ! inositol trisphosphate kinase activity GO:0051766 7 7 0,000 7,106E-03 0,0229438 ! apical protein localization GO:0045176 7 7 0,000 7,106E-03 0,02292307 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,106E-03 0,02290239 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,106E-03 0,02288173 ! virion binding GO:0046790 10 7 0,000 7,106E-03 0,02286112 ! nonprotein amino acid metabolic process GO:0019794 7 7 0,000 7,106E-03 0,02284054 ! protein prenyltransferase activity GO:0008318 7 7 0,000 7,106E-03 0,02282 ! protein modification by small protein removal GO:0070646 7 7 0,000 7,106E-03 0,0227995 ! adult feeding behavior GO:0008343 7 7 0,000 7,106E-03 0,02277903 ! CoA carboxylase activity GO:0016421 7 7 0,000 7,106E-03 0,0227586 ! microtubule basal body GO:0005932 7 7 0,000 7,106E-03 0,02273821 ! positive regulation of NF-kappaB import into nucleus GO:0042346 7 7 0,000 7,106E-03 0,02271785 ! embryonic heart tube development GO:0035050 7 7 0,000 7,106E-03 0,02269753 ! kainate selective glutamate receptor activity GO:0015277 7 7 0,000 7,106E-03 0,02267725 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,106E-03 0,022657 ! positive regulation of smooth muscle contraction GO:0045987 7 7 0,000 7,106E-03 0,02263679 ! rRNA transcription GO:0009303 8 8 0,000 8,117E-03 0,02583529 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 8 8 0,000 8,117E-03 0,02581228 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,117E-03 0,02578932 ! sodium:hydrogen antiporter activity GO:0015385 8 8 0,000 8,117E-03 0,02576639 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cation:chloride symporter activity GO:0015377 9 8 0,000 8,117E-03 0,02574351 ! positive regulation of small GTPase mediated signal transduction GO:0051057 8 8 0,000 8,117E-03 0,02572067 GO:0046579|positive regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 8 0,000 8,117E-03 0,02569787 ! male meiosis GO:0007140 8 8 0,000 8,117E-03 0,02567511 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8 8 0,000 8,117E-03 0,02565238 ! N-glycan processing GO:0006491 8 8 0,000 8,117E-03 0,0256297 ! regulation of smooth muscle cell migration GO:0014910 9 8 0,000 8,117E-03 0,02560706 ! protein self-association GO:0043621 8 8 0,000 8,117E-03 0,02558446 ! RNA methylation GO:0001510 8 8 0,000 8,117E-03 0,0255619 ! prostaglandin biosynthetic process GO:0001516 9 8 0,000 8,117E-03 0,02553938 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 8 8 0,000 8,117E-03 0,0255169 ! regulation of activated T cell proliferation GO:0046006 8 8 0,000 8,117E-03 0,02549445 ! hexokinase activity GO:0004396 8 8 0,000 8,117E-03 0,02547205 ! neurofilament cytoskeleton GO:0060053 8 8 0,000 8,117E-03 0,02544969 ! guanylate cyclase activity GO:0004383 8 8 0,000 8,117E-03 0,02542736 ! integral to mitochondrial membrane GO:0032592 8 8 0,000 8,117E-03 0,02540508 ! troponin complex GO:0005861 9 8 0,000 8,117E-03 0,02538283 ! smoothened signaling pathway GO:0007224 8 8 0,000 8,117E-03 0,02536062 ! keratinocyte proliferation GO:0043616 8 8 0,000 8,117E-03 0,02533846 ! negative regulation of muscle cell differentiation GO:0051148 8 8 0,000 8,117E-03 0,02531633 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,117E-03 0,02529424 ! reflex GO:0060004 11 8 0,000 8,117E-03 0,02527218 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,117E-03 0,02525017 ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,117E-03 0,02522819 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,117E-03 0,02520626 ! protein targeting to ER GO:0045047 9 8 0,000 8,117E-03 0,02518436 ! positive regulation of survival gene product expression GO:0045885 8 8 0,000 8,117E-03 0,02516249 ! arginine catabolic process GO:0006527 8 8 0,000 8,117E-03 0,02514067 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,117E-03 0,02511889 ! malate dehydrogenase activity GO:0016615 8 8 0,000 8,117E-03 0,02509714 ! inner mitochondrial membrane organization GO:0007007 9 8 0,000 8,117E-03 0,02507543 ! telomere maintenance via telomerase GO:0007004 8 8 0,000 8,117E-03 0,02505375 GO:0010833|telomere maintenance via telomere lengthening, ! DNA secondary structure binding GO:0000217 8 8 0,000 8,117E-03 0,02503212 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 9 8 0,000 8,117E-03 0,02501052 ! proline metabolic process GO:0006560 9 8 0,000 8,117E-03 0,02498896 ! melanosome membrane GO:0033162 10 8 0,000 8,117E-03 0,02496744 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,117E-03 0,02494595 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 8,117E-03 0,0249245 ! melanin metabolic process GO:0006582 9 8 0,000 8,117E-03 0,02490309 ! death receptor activity GO:0005035 8 8 0,000 8,117E-03 0,02488171 ! Golgi lumen GO:0005796 8 8 0,000 8,117E-03 0,02486037 ! smooth endoplasmic reticulum GO:0005790 9 8 0,000 8,117E-03 0,02483907 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 8,117E-03 0,0248178 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 9 8 0,000 8,117E-03 0,02479657 GO:0048500|signal recognition particle, ! Golgi cisterna GO:0031985 9 8 0,000 8,117E-03 0,02477538 ! positive regulation of mesenchymal cell proliferation GO:0002053 8 8 0,000 8,117E-03 0,02475422 ! Rac protein signal transduction GO:0016601 8 8 0,000 8,117E-03 0,0247331 ! positive regulation of calcium ion transport into cytosol GO:0010524 11 8 0,000 8,117E-03 0,02471202 ! lens development in camera-type eye GO:0002088 8 8 0,000 8,117E-03 0,02469097 ! positive regulation of vasodilation GO:0045909 8 8 0,000 8,117E-03 0,02466995 ! intestinal cholesterol absorption GO:0030299 8 8 0,000 8,117E-03 0,02464897 ! negative regulation of muscle contraction GO:0045932 9 8 0,000 8,117E-03 0,02462803 ! positive regulation vascular endothelial growth factor production GO:0010575 8 8 0,000 8,117E-03 0,02460713 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 8 8 0,000 8,117E-03 0,02458625 ! Schwann cell differentiation GO:0014037 8 8 0,000 8,117E-03 0,02456542 ! sodium:dicarboxylate symporter activity GO:0017153 8 8 0,000 8,117E-03 0,02454462 ! axon guidance receptor activity GO:0008046 8 8 0,000 8,117E-03 0,02452385 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,117E-03 0,02450312 ! response to tropane GO:0014073 10 8 0,000 8,117E-03 0,02448243 GO:0042220|response to cocaine, ! purine nucleoside triphosphate catabolic process GO:0009146 8 8 0,000 8,117E-03 0,02446177 ! melanosome localization GO:0032400 8 8 0,000 8,117E-03 0,02444114 ! response to amine stimulus GO:0014075 10 8 0,000 8,117E-03 0,02442055 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 8 8 0,000 8,117E-03 0,02439999 ! sphingomyelin metabolic process GO:0006684 9 8 0,000 8,117E-03 0,02437947 ! regulation of mitochondrial membrane potential GO:0051881 8 8 0,000 8,117E-03 0,02435899 ! synaptic vesicle endocytosis GO:0048488 8 8 0,000 8,117E-03 0,02433853 ! holo TFIIH complex GO:0005675 8 8 0,000 8,117E-03 0,02431812 ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,117E-03 0,02429773 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 8 0,000 8,117E-03 0,02427738 ! negative regulation of cytokine secretion GO:0050710 8 8 0,000 8,117E-03 0,02425707 ! regulation of myoblast differentiation GO:0045661 8 8 0,000 8,117E-03 0,02423678 ! vitamin transporter activity GO:0051183 8 8 0,000 8,117E-03 0,02421654 ! positive regulation of erythrocyte differentiation GO:0045648 8 8 0,000 8,117E-03 0,02419632 ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,117E-03 0,02417614 ! heparan sulfate sulfotransferase activity GO:0034483 8 8 0,000 8,117E-03 0,02415599 ! regulation of epidermal cell differentiation GO:0045604 8 8 0,000 8,117E-03 0,02413588 ! regulation of T-helper 2 cell differentiation GO:0045628 8 8 0,000 8,117E-03 0,0241158 ! positive regulation of T-helper cell differentiation GO:0045624 8 8 0,000 8,117E-03 0,02409576 ! branched chain family amino acid catabolic process GO:0009083 8 8 0,000 8,117E-03 0,02407574 ! regulation of synaptogenesis GO:0051963 8 8 0,000 8,117E-03 0,02405576 ! oocyte differentiation GO:0009994 8 8 0,000 8,117E-03 0,02403582 GO:0048599|oocyte development, ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 8 8 0,000 8,117E-03 0,0240159 GO:0003756|protein disulfide isomerase activity, ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,117E-03 0,02399602 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 8 0,000 8,117E-03 0,02397617 ! beta-1,3-galactosyltransferase activity GO:0048531 8 8 0,000 8,117E-03 0,02395636 ! establishment of pigment granule localization GO:0051905 8 8 0,000 8,117E-03 0,02393658 ! regulation of telomere maintenance GO:0032204 8 8 0,000 8,117E-03 0,02391683 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 8 0,000 8,117E-03 0,02389711 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,117E-03 0,02387742 GO:0006043|glucosamine catabolic process, ! regulation of amino acid transport GO:0051955 8 8 0,000 8,117E-03 0,02385777 ! B cell receptor signaling pathway GO:0050853 14 8 0,000 8,117E-03 0,02383815 ! T cell receptor signaling pathway GO:0050852 13 8 0,000 8,117E-03 0,02381857 ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 8 0,000 8,117E-03 0,02379901 ! cholesterol transporter activity GO:0017127 8 8 0,000 8,117E-03 0,02377949 ! GABA receptor binding GO:0050811 8 8 0,000 8,117E-03 0,02375999 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 8 8 0,000 8,117E-03 0,02374054 ! regulation of microtubule polymerization GO:0031113 8 8 0,000 8,117E-03 0,02372111 ! regulation of developmental growth GO:0048638 8 8 0,000 8,117E-03 0,02370171 ! GMP binding GO:0019002 10 8 0,000 8,117E-03 0,02368235 GO:0030553|cGMP binding, ! regulation of epithelial cell differentiation GO:0030856 8 8 0,000 8,117E-03 0,02366302 ! negative regulation of cellular catabolic process GO:0031330 9 8 0,000 8,117E-03 0,02364371 ! prostate gland development GO:0030850 8 8 0,000 8,117E-03 0,02362444 ! 7S RNA binding GO:0008312 9 8 0,000 8,117E-03 0,02360521 ! phosphate transport GO:0006817 9 8 0,000 8,117E-03 0,023586 ! neutral lipid catabolic process GO:0046461 8 8 0,000 8,117E-03 0,02356682 ! protein phosphorylated amino acid binding GO:0045309 10 8 0,000 8,117E-03 0,02354768 ! reproductive behavior GO:0019098 8 8 0,000 8,117E-03 0,02352857 ! cell volume homeostasis GO:0006884 9 8 0,000 8,117E-03 0,02350948 ! regulation of long-term neuronal synaptic plasticity GO:0048169 8 8 0,000 8,117E-03 0,02349043 ! oligopeptide transport GO:0006857 8 8 0,000 8,117E-03 0,02347141 GO:0015198|oligopeptide transporter activity, ! induction of positive chemotaxis GO:0050930 8 8 0,000 8,117E-03 0,02345242 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,117E-03 0,02343346 ! regulation of dopamine metabolic process GO:0042053 8 8 0,000 8,117E-03 0,02341453 GO:0042069|regulation of catecholamine metabolic process, ! regulation of carbohydrate biosynthetic process GO:0043255 8 8 0,000 8,117E-03 0,02339564 ! titin binding GO:0031432 8 8 0,000 8,117E-03 0,02337677 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,117E-03 0,02335793 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 8 0,000 8,117E-03 0,02333913 ! bone resorption GO:0045453 8 8 0,000 8,117E-03 0,02332035 ! glycerolipid catabolic process GO:0046503 8 8 0,000 8,117E-03 0,0233016 ! endoderm development GO:0007492 8 8 0,000 8,117E-03 0,02328289 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,117E-03 0,0232642 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,117E-03 0,02324554 ! astrocyte differentiation GO:0048708 8 8 0,000 8,117E-03 0,02322692 ! embryonic cranial skeleton morphogenesis GO:0048701 8 8 0,000 8,117E-03 0,02320832 ! syncytium formation GO:0006949 8 8 0,000 8,117E-03 0,02318975 ! embryonic eye morphogenesis GO:0048048 10 8 0,000 8,117E-03 0,02317122 ! B cell proliferation GO:0042100 8 8 0,000 8,117E-03 0,02315271 ! mannose metabolic process GO:0006013 10 8 0,000 8,117E-03 0,02313423 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 8 8 0,000 8,117E-03 0,02311578 ! asymmetric protein localization GO:0008105 8 8 0,000 8,117E-03 0,02309737 ! tumor necrosis factor binding GO:0043120 8 8 0,000 8,117E-03 0,02307898 ! synaptic transmission, glutamatergic GO:0035249 9 8 0,000 8,117E-03 0,02306062 ! neuron apoptosis GO:0051402 8 8 0,000 8,117E-03 0,02304228 ! macroautophagy GO:0016236 9 8 0,000 8,117E-03 0,02302398 ! Cajal body GO:0015030 8 8 0,000 8,117E-03 0,02300571 ! O-methyltransferase activity GO:0008171 9 8 0,000 8,117E-03 0,02298747 ! H4/H2A histone acetyltransferase complex GO:0043189 9 8 0,000 8,117E-03 0,02296925 ! PcG protein complex GO:0031519 8 8 0,000 8,117E-03 0,02295106 ! ferric iron binding GO:0008199 9 8 0,000 8,117E-03 0,02293291 ! spindle checkpoint GO:0031577 8 8 0,000 8,117E-03 0,02291478 ! G1 DNA damage checkpoint GO:0031571 8 8 0,000 8,117E-03 0,02289668 ! segment specification GO:0007379 8 8 0,000 8,117E-03 0,02287861 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,117E-03 0,02286056 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 8,117E-03 0,02284255 ! cellular extravasation GO:0045123 9 8 0,000 8,117E-03 0,02282456 ! pronucleus GO:0045120 8 8 0,000 8,117E-03 0,0228066 ! regulation of insulin receptor signaling pathway GO:0046626 8 8 0,000 8,117E-03 0,02278867 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 8 8 0,000 8,117E-03 0,02277077 ! Rac GTPase activator activity GO:0030675 9 8 0,000 8,117E-03 0,0227529 ! transcription-coupled nucleotide-excision repair GO:0006283 9 8 0,000 8,117E-03 0,02273505 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,117E-03 0,02271724 ! antigen processing and presentation of exogenous antigen GO:0019884 9 8 0,000 8,117E-03 0,02269945 ! DNA ligation GO:0006266 8 8 0,000 8,117E-03 0,02268169 ! regulation of T cell differentiation in the thymus GO:0033081 8 8 0,000 8,117E-03 0,02266395 ! negative regulation of systemic arterial blood pressure GO:0003085 8 8 0,000 8,117E-03 0,02264625 ! multicellular organismal aging GO:0010259 8 8 0,000 8,117E-03 0,02262857 ! erythrocyte development GO:0048821 8 8 0,000 8,117E-03 0,02261092 ! interleukin-1 receptor activity GO:0004908 8 8 0,000 8,117E-03 0,02259329 ! positive regulation of monooxygenase activity GO:0032770 8 8 0,000 8,117E-03 0,0225757 ! protein import into peroxisome matrix GO:0016558 8 8 0,000 8,117E-03 0,02255813 ! ribosome binding GO:0043022 9 8 0,000 8,117E-03 0,02254059 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,117E-03 0,02252307 ! mRNA polyadenylation GO:0006378 8 8 0,000 8,117E-03 0,02250559 ! sodium:amino acid symporter activity GO:0005283 8 8 0,000 8,117E-03 0,02248813 ! adenylyltransferase activity GO:0070566 8 8 0,000 8,117E-03 0,02247069 ! zymogen activation GO:0031638 8 8 0,000 8,117E-03 0,02245329 ! axonal fasciculation GO:0007413 8 8 0,000 8,117E-03 0,02243591 ! T cell homeostasis GO:0043029 9 8 0,000 8,117E-03 0,02241856 ! negative regulation of nuclear division GO:0051784 8 8 0,000 8,117E-03 0,02240123 GO:0045839|negative regulation of mitosis, ! caspase inhibitor activity GO:0043027 8 8 0,000 8,117E-03 0,02238393 ! energy coupled proton transport, against electrochemical gradient GO:0015988 8 8 0,000 8,117E-03 0,02236666 GO:0015991|ATP hydrolysis coupled proton transport, ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 8 8 0,000 8,117E-03 0,02234942 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,117E-03 0,0223322 ! thyroid hormone receptor activity GO:0004887 8 8 0,000 8,117E-03 0,02231501 ! wide pore channel activity GO:0022829 8 8 0,000 8,117E-03 0,02229784 ! ligand-regulated transcription factor activity GO:0003706 8 8 0,000 8,117E-03 0,0222807 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,117E-03 0,02226359 ! hormone catabolic process GO:0042447 8 8 0,000 8,117E-03 0,0222465 ! positive regulation of ATPase activity GO:0032781 8 8 0,000 8,117E-03 0,02222944 ! biogenic amine catabolic process GO:0042402 11 8 0,000 8,117E-03 0,02221241 ! Notch binding GO:0005112 8 8 0,000 8,117E-03 0,0221954 ! death receptor binding GO:0005123 8 8 0,000 8,117E-03 0,02217842 ! ATPase regulator activity GO:0060590 8 8 0,000 8,117E-03 0,02216146 ! pyrimidine base metabolic process GO:0006206 10 8 0,000 8,117E-03 0,02214453 ! epidermal growth factor receptor binding GO:0005154 9 8 0,000 8,117E-03 0,02212763 ! dihydropyridine-sensitive calcium channel activity GO:0015270 8 8 0,000 8,117E-03 0,02211075 ! calcium-release channel activity GO:0015278 8 8 0,000 8,117E-03 0,0220939 ! tubulin-tyrosine ligase activity GO:0004835 8 8 0,000 8,117E-03 0,02207707 ! fusion of sperm to egg plasma membrane GO:0007342 9 8 0,000 8,117E-03 0,02206027 ! nucleus localization GO:0051647 10 8 0,000 8,117E-03 0,02204349 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,117E-03 0,02202674 ! negative regulation of immune effector process GO:0002698 12 8 0,000 8,117E-03 0,02201002 ! C-X-C chemokine receptor activity GO:0016494 8 8 0,000 8,117E-03 0,02199332 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,117E-03 0,02197664 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 9 9 0,000 9,128E-03 0,02469327 ! respiratory burst GO:0045730 9 9 0,000 9,128E-03 0,02467457 ! telencephalon cell migration GO:0022029 9 9 0,000 9,128E-03 0,02465591 ! 'de novo' posttranslational protein folding GO:0051084 9 9 0,000 9,128E-03 0,02463727 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 9,128E-03 0,02461866 ! cGMP metabolic process GO:0046068 9 9 0,000 9,128E-03 0,02460008 GO:0006182|cGMP biosynthetic process, ! regulation of epidermal growth factor receptor activity GO:0007176 9 9 0,000 9,128E-03 0,02458153 GO:0010469|regulation of receptor activity, ! inositol trisphosphate phosphatase activity GO:0046030 11 9 0,000 9,128E-03 0,02456301 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! axon part GO:0033267 12 9 0,000 9,128E-03 0,02454451 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9 9 0,000 9,128E-03 0,02452604 ! RNA polyadenylation GO:0043631 9 9 0,000 9,128E-03 0,0245076 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 9 0,000 9,128E-03 0,02448919 ! regulation of receptor-mediated endocytosis GO:0048259 9 9 0,000 9,128E-03 0,0244708 ! artery development GO:0060840 9 9 0,000 9,128E-03 0,02445245 GO:0048844|artery morphogenesis, ! middle ear morphogenesis GO:0042474 9 9 0,000 9,128E-03 0,02443412 ! regulation of mesenchymal cell proliferation GO:0010464 9 9 0,000 9,128E-03 0,02441581 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 12 9 0,000 9,128E-03 0,02439754 GO:0046330|positive regulation of JNK cascade, ! positive regulation of heart contraction GO:0045823 10 9 0,000 9,128E-03 0,02437929 ! lung alveolus development GO:0048286 9 9 0,000 9,128E-03 0,02436107 ! ciliary or flagellar motility GO:0001539 9 9 0,000 9,128E-03 0,02434288 ! beta-amyloid binding GO:0001540 10 9 0,000 9,128E-03 0,02432471 ! pathogenesis GO:0009405 9 9 0,000 9,128E-03 0,02430657 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 10 9 0,000 9,128E-03 0,02428846 ! regulated secretory pathway GO:0045055 9 9 0,000 9,128E-03 0,02427037 ! regulation of S phase of mitotic cell cycle GO:0007090 9 9 0,000 9,128E-03 0,02425231 ! estrogen receptor binding GO:0030331 9 9 0,000 9,128E-03 0,02423428 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 10 9 0,000 9,128E-03 0,02421628 ! regulation of defense response to virus by virus GO:0050690 9 9 0,000 9,128E-03 0,0241983 ! histidine metabolic process GO:0006547 9 9 0,000 9,128E-03 0,02418035 GO:0009075|histidine family amino acid metabolic process, ! L-phenylalanine metabolic process GO:0006558 10 9 0,000 9,128E-03 0,02416242 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 9 9 0,000 9,128E-03 0,02414453 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 9 9 0,000 9,128E-03 0,02412666 ! nucleobase biosynthetic process GO:0046112 11 9 0,000 9,128E-03 0,02410881 ! regulation of Cdc42 protein signal transduction GO:0032489 9 9 0,000 9,128E-03 0,02409099 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of calcium ion transport into cytosol GO:0010522 12 9 0,000 9,128E-03 0,0240732 ! entry into host cell GO:0030260 9 9 0,000 9,128E-03 0,02405543 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 9 9 0,000 9,128E-03 0,02403769 ! regulation of lipoprotein lipase activity GO:0051004 9 9 0,000 9,128E-03 0,02401998 ! retinoic acid metabolic process GO:0042573 9 9 0,000 9,128E-03 0,02400229 ! retinol metabolic process GO:0042572 9 9 0,000 9,128E-03 0,02398463 ! behavioral fear response GO:0001662 9 9 0,000 9,128E-03 0,02396699 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 10 9 0,000 9,128E-03 0,02394938 ! regulation of vascular endothelial growth factor production GO:0010574 9 9 0,000 9,128E-03 0,0239318 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9 9 0,000 9,128E-03 0,02391424 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! motor axon guidance GO:0008045 9 9 0,000 9,128E-03 0,02389671 ! regulation of gliogenesis GO:0014013 9 9 0,000 9,128E-03 0,0238792 GO:0045685|regulation of glial cell differentiation, ! recycling endosome membrane GO:0055038 10 9 0,000 9,128E-03 0,02386172 ! pigment granule localization GO:0051875 9 9 0,000 9,128E-03 0,02384427 ! platelet-derived growth factor binding GO:0048407 10 9 0,000 9,128E-03 0,02382684 ! glycosphingolipid biosynthetic process GO:0006688 9 9 0,000 9,128E-03 0,02380943 ! nucleoside diphosphate metabolic process GO:0009132 10 9 0,000 9,128E-03 0,02379205 ! phosphoinositide 3-kinase cascade GO:0014065 9 9 0,000 9,128E-03 0,0237747 ! cell wall macromolecule catabolic process GO:0016998 10 9 0,000 9,128E-03 0,02375737 ! purine ribonucleotide catabolic process GO:0009154 9 9 0,000 9,128E-03 0,02374007 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 9 9 0,000 9,128E-03 0,02372279 ! positive regulation of Rho GTPase activity GO:0032321 9 9 0,000 9,128E-03 0,02370554 ! nitric oxide metabolic process GO:0046209 9 9 0,000 9,128E-03 0,02368831 GO:0006809|nitric oxide biosynthetic process, ! mismatch repair complex GO:0032300 9 9 0,000 9,128E-03 0,0236711 ! icosanoid secretion GO:0032309 9 9 0,000 9,128E-03 0,02365393 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 10 9 0,000 9,128E-03 0,02363677 GO:0010092|specification of organ identity, ! retinal ganglion cell axon guidance GO:0031290 9 9 0,000 9,128E-03 0,02361965 ! morphogenesis of a polarized epithelium GO:0001738 9 9 0,000 9,128E-03 0,02360254 ! sterol catabolic process GO:0016127 9 9 0,000 9,128E-03 0,02358546 GO:0006707|cholesterol catabolic process, ! prophase GO:0051324 9 9 0,000 9,128E-03 0,02356841 ! peptidyl-lysine modification GO:0018205 9 9 0,000 9,128E-03 0,02355138 ! pancreatic ribonuclease activity GO:0004522 9 9 0,000 9,128E-03 0,02353438 ! clathrin coat of coated pit GO:0030132 12 9 0,000 9,128E-03 0,0235174 ! SNARE complex GO:0031201 10 9 0,000 9,128E-03 0,02350044 ! ubiquinone metabolic process GO:0006743 10 9 0,000 9,128E-03 0,02348351 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! snRNA binding GO:0017069 9 9 0,000 9,128E-03 0,0234666 ! regulation of macrophage differentiation GO:0045649 9 9 0,000 9,128E-03 0,02344972 ! regulation of osteoclast differentiation GO:0045670 10 9 0,000 9,128E-03 0,02343286 ! positive regulation of neuron differentiation GO:0045666 9 9 0,000 9,128E-03 0,02341603 ! negative regulation of lymphocyte differentiation GO:0045620 9 9 0,000 9,128E-03 0,02339922 ! methionine biosynthetic process GO:0009086 10 9 0,000 9,128E-03 0,02338243 ! peptidoglycan binding GO:0042834 9 9 0,000 9,128E-03 0,02336567 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 9,128E-03 0,02334893 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! pyridine nucleotide biosynthetic process GO:0019363 9 9 0,000 9,128E-03 0,02333222 ! intramolecular transferase activity, phosphotransferases GO:0016868 9 9 0,000 9,128E-03 0,02331553 ! cholesterol efflux GO:0033344 9 9 0,000 9,128E-03 0,02329886 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 9 9 0,000 9,128E-03 0,02328222 ! metalloenzyme inhibitor activity GO:0048551 10 9 0,000 9,128E-03 0,0232656 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 9 9 0,000 9,128E-03 0,02324901 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 9,128E-03 0,02323244 ! detection of calcium ion GO:0005513 10 9 0,000 9,128E-03 0,02321589 ! negative regulation of glucose import GO:0046325 9 9 0,000 9,128E-03 0,02319937 GO:0010829|negative regulation of glucose transport, ! regulation of fibrinolysis GO:0051917 9 9 0,000 9,128E-03 0,02318287 ! trophectodermal cell differentiation GO:0001829 9 9 0,000 9,128E-03 0,02316639 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 9 0,000 9,128E-03 0,02314994 ! hydrolase activity, acting on ether bonds GO:0016801 9 9 0,000 9,128E-03 0,02313351 ! desmosome GO:0030057 9 9 0,000 9,128E-03 0,0231171 ! prepulse inhibition GO:0060134 9 9 0,000 9,128E-03 0,02310072 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 15 9 0,000 9,128E-03 0,02308436 ! negative regulation of B cell activation GO:0050869 9 9 0,000 9,128E-03 0,02306802 ! anchoring collagen GO:0030934 9 9 0,000 9,128E-03 0,02305171 ! axon extension GO:0048675 10 9 0,000 9,128E-03 0,02303541 ! neuron fate specification GO:0048665 9 9 0,000 9,128E-03 0,02301915 ! positive regulation of glucose metabolic process GO:0010907 9 9 0,000 9,128E-03 0,0230029 ! cortical actin cytoskeleton organization GO:0030866 9 9 0,000 9,128E-03 0,02298668 ! virus-host interaction GO:0019048 13 9 0,000 9,128E-03 0,02297048 ! rough endoplasmic reticulum membrane GO:0030867 9 9 0,000 9,128E-03 0,0229543 ! pentose-phosphate shunt GO:0006098 9 9 0,000 9,128E-03 0,02293815 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 9,128E-03 0,02292202 ! DNA bending activity GO:0008301 9 9 0,000 9,128E-03 0,02290591 ! social behavior GO:0035176 9 9 0,000 9,128E-03 0,02288983 ! secondary active sulfate transmembrane transporter activity GO:0008271 9 9 0,000 9,128E-03 0,02287376 ! dipeptidyl-peptidase activity GO:0008239 11 9 0,000 9,128E-03 0,02285772 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 9,128E-03 0,0228417 ! very-low-density lipoprotein particle GO:0034361 9 9 0,000 9,128E-03 0,02282571 GO:0034385|triglyceride-rich lipoprotein particle, ! high-density lipoprotein particle GO:0034364 9 9 0,000 9,128E-03 0,02280973 ! amyloid precursor protein metabolic process GO:0042982 10 9 0,000 9,128E-03 0,02279378 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 11 9 0,000 9,128E-03 0,02277786 ! blood vessel remodeling GO:0001974 10 9 0,000 9,128E-03 0,02276195 ! C-X-C chemokine binding GO:0019958 9 9 0,000 9,128E-03 0,02274606 ! 3'-5'-exoribonuclease activity GO:0000175 9 9 0,000 9,128E-03 0,0227302 ! exosome (RNase complex) GO:0000178 9 9 0,000 9,128E-03 0,02271436 ! inositol phosphate-mediated signaling GO:0048016 9 9 0,000 9,128E-03 0,02269855 ! DNA N-glycosylase activity GO:0019104 9 9 0,000 9,128E-03 0,02268275 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 9 9 0,000 9,128E-03 0,02266698 GO:0033549|MAP kinase phosphatase activity, ! ER overload response GO:0006983 11 9 0,000 9,128E-03 0,02265122 ! zinc ion transmembrane transporter activity GO:0005385 9 9 0,000 9,128E-03 0,02263549 ! glucose transmembrane transporter activity GO:0005355 9 9 0,000 9,128E-03 0,02261979 ! retrograde transport, endosome to Golgi GO:0042147 10 9 0,000 9,128E-03 0,0226041 ! phagocytosis, engulfment GO:0006911 10 9 0,000 9,128E-03 0,02258843 ! neurotransmitter biosynthetic process GO:0042136 10 9 0,000 9,128E-03 0,02257279 ! carbohydrate phosphatase activity GO:0019203 9 9 0,000 9,128E-03 0,02255717 ! glutathione peroxidase activity GO:0004602 9 9 0,000 9,128E-03 0,02254157 ! acyl-CoA thioesterase activity GO:0016291 9 9 0,000 9,128E-03 0,02252599 ! lysophospholipase activity GO:0004622 9 9 0,000 9,128E-03 0,02251044 ! brain morphogenesis GO:0048854 9 9 0,000 9,128E-03 0,0224949 ! apolipoprotein binding GO:0034185 9 9 0,000 9,128E-03 0,02247939 ! synaptic vesicle membrane GO:0030672 9 9 0,000 9,128E-03 0,02246389 ! RNA-dependent DNA replication GO:0006278 9 9 0,000 9,128E-03 0,02244842 ! positive regulation of systemic arterial blood pressure GO:0003084 10 9 0,000 9,128E-03 0,02243297 ! kinesin binding GO:0019894 9 9 0,000 9,128E-03 0,02241755 ! nucleoside bisphosphate metabolic process GO:0033865 10 9 0,000 9,128E-03 0,02240214 ! renal water homeostasis GO:0003091 9 9 0,000 9,128E-03 0,02238675 ! positive regulation of interleukin-6 production GO:0032755 9 9 0,000 9,128E-03 0,02237139 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 9,128E-03 0,02235604 ! histone methylation GO:0016571 10 9 0,000 9,128E-03 0,02234072 ! mRNA cleavage GO:0006379 9 9 0,000 9,128E-03 0,02232542 ! negative regulation of tumor necrosis factor production GO:0032720 9 9 0,000 9,128E-03 0,02231014 ! sarcoplasmic reticulum membrane GO:0033017 10 9 0,000 9,128E-03 0,02229488 ! opioid receptor activity GO:0004985 9 9 0,000 9,128E-03 0,02227964 ! cellular metabolic compound salvage GO:0043094 12 9 0,000 9,128E-03 0,02226442 ! salivary gland development GO:0007431 10 9 0,000 9,128E-03 0,02224922 ! glucosidase activity GO:0015926 10 9 0,000 9,128E-03 0,02223405 ! adrenoceptor activity GO:0004935 11 9 0,000 9,128E-03 0,02221889 ! positive regulation of leukocyte migration GO:0002687 9 9 0,000 9,128E-03 0,02220375 ! purine base metabolic process GO:0006144 11 9 0,000 9,128E-03 0,02218864 ! mRNA 3'-UTR binding GO:0003730 9 9 0,000 9,128E-03 0,02217354 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 9 9 0,000 9,128E-03 0,02215847 ! receptor inhibitor activity GO:0030547 9 9 0,000 9,128E-03 0,02214342 GO:0048019|receptor antagonist activity, ! negative regulation of BMP signaling pathway GO:0030514 9 9 0,000 9,128E-03 0,02212839 ! ionotropic glutamate receptor complex GO:0008328 11 9 0,000 9,128E-03 0,02211337 ! transforming growth factor beta receptor binding GO:0005160 9 9 0,000 9,128E-03 0,02209838 ! palmitoyltransferase activity GO:0016409 9 9 0,000 9,128E-03 0,02208341 ! arylsulfatase activity GO:0004065 9 9 0,000 9,128E-03 0,02206846 ! phospholipase inhibitor activity GO:0004859 9 9 0,000 9,128E-03 0,02205353 ! behavioral response to nicotine GO:0035095 9 9 0,000 9,128E-03 0,02203861 ! adenylate kinase activity GO:0004017 10 9 0,000 9,128E-03 0,02202372 ! alcohol dehydrogenase (NAD) activity GO:0004022 9 9 0,000 9,128E-03 0,02200885 ! mitochondrion localization GO:0051646 9 9 0,000 9,128E-03 0,021994 ! localization within membrane GO:0051668 9 9 0,000 9,128E-03 0,02197917 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 10 0,000 0,0101371 0,02439326 ! lipid particle GO:0005811 10 10 0,000 0,0101371 0,02437683 ! myotube differentiation GO:0014902 10 10 0,000 0,0101371 0,02436043 ! generation of neurons in the forebrain GO:0021872 11 10 0,000 0,0101371 0,02434405 ! regulation of cellular amine metabolic process GO:0033238 10 10 0,000 0,0101371 0,02432769 ! synapsis GO:0007129 10 10 0,000 0,0101371 0,02431135 GO:0070192|chromosome organization involved in meiosis, ! filopodium assembly GO:0046847 12 10 0,000 0,0101371 0,02429503 ! UTP metabolic process GO:0046051 10 10 0,000 0,0101371 0,02427874 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 10 10 0,000 0,0101371 0,02426247 ! COPI coating of Golgi vesicle GO:0048205 10 10 0,000 0,0101371 0,02424621 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 10 10 0,000 0,0101371 0,02422999 ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,0101371 0,02421378 ! macromolecule transmembrane transporter activity GO:0022884 10 10 0,000 0,0101371 0,02419759 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! lipoprotein receptor binding GO:0070325 10 10 0,000 0,0101371 0,02418143 GO:0050750|low-density lipoprotein receptor binding, ! thyroid hormone receptor coactivator activity GO:0030375 10 10 0,000 0,0101371 0,02416529 GO:0010861|thyroid hormone receptor activator activity, ! auditory receptor cell differentiation GO:0042491 11 10 0,000 0,0101371 0,02414916 ! regulation of chemokine biosynthetic process GO:0045073 10 10 0,000 0,0101371 0,02413307 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 10 10 0,000 0,0101371 0,02411699 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,0101371 0,02410093 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 10 0,000 0,0101371 0,0240849 ! nucleotide-sugar metabolic process GO:0009225 11 10 0,000 0,0101371 0,02406888 ! regulation of catecholamine secretion GO:0050433 10 10 0,000 0,0101371 0,02405289 ! melanocyte differentiation GO:0030318 10 10 0,000 0,0101371 0,02403692 GO:0050931|pigment cell differentiation, ! ER-Golgi intermediate compartment membrane GO:0033116 10 10 0,000 0,0101371 0,02402097 ! deoxyribonucleotide catabolic process GO:0009264 10 10 0,000 0,0101371 0,02400504 ! L-serine metabolic process GO:0006563 11 10 0,000 0,0101371 0,02398913 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 10 10 0,000 0,0101371 0,02397324 ! lipase inhibitor activity GO:0055102 10 10 0,000 0,0101371 0,02395738 ! autophagic vacuole GO:0005776 11 10 0,000 0,0101371 0,02394153 ! NAD metabolic process GO:0019674 10 10 0,000 0,0101371 0,02392571 ! stereocilium GO:0032420 10 10 0,000 0,0101371 0,02390991 GO:0032421|stereocilium bundle, ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,0101371 0,02389412 ! regulation of sodium ion transport GO:0002028 10 10 0,000 0,0101371 0,02387836 ! forebrain cell migration GO:0021885 10 10 0,000 0,0101371 0,02386262 ! organelle subcompartment GO:0031984 11 10 0,000 0,0101371 0,0238469 ! chondrocyte differentiation GO:0002062 10 10 0,000 0,0101371 0,0238312 ! negative regulation of ossification GO:0030279 10 10 0,000 0,0101371 0,02381553 ! regulation of smoothened signaling pathway GO:0008589 10 10 0,000 0,0101371 0,02379987 ! heparan sulfate proteoglycan metabolic process GO:0030201 10 10 0,000 0,0101371 0,02378423 ! phosphatidylcholine biosynthetic process GO:0006656 12 10 0,000 0,0101371 0,02376861 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 10 10 0,000 0,0101371 0,02375302 ! protein homotetramerization GO:0051289 11 10 0,000 0,0101371 0,02373744 ! regulation of dephosphorylation GO:0035303 12 10 0,000 0,0101371 0,02372189 ! oligodendrocyte development GO:0014003 10 10 0,000 0,0101371 0,02370635 ! positive regulation of phagocytosis GO:0050766 10 10 0,000 0,0101371 0,02369084 ! response to dsRNA GO:0043331 10 10 0,000 0,0101371 0,02367534 ! mismatch repair complex binding GO:0032404 11 10 0,000 0,0101371 0,02365987 ! snRNA metabolic process GO:0016073 10 10 0,000 0,0101371 0,02364441 GO:0016180|snRNA processing, ! cranial nerve development GO:0021545 10 10 0,000 0,0101371 0,02362898 ! fucose catabolic process GO:0019317 11 10 0,000 0,0101371 0,02361357 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,0101371 0,02359817 ! retinal binding GO:0016918 10 10 0,000 0,0101371 0,0235828 ! leukocyte activation during immune response GO:0002366 10 10 0,000 0,0101371 0,02356745 GO:0002263|cell activation during immune response, ! cerebellum morphogenesis GO:0021587 11 10 0,000 0,0101371 0,02355211 GO:0021696|cerebellar cortex morphogenesis, ! photoreceptor outer segment GO:0001750 10 10 0,000 0,0101371 0,0235368 ! negative regulation of MAPKKK cascade GO:0043409 10 10 0,000 0,0101371 0,02352151 ! regulation of T-helper 2 type immune response GO:0002828 10 10 0,000 0,0101371 0,02350623 ! ribonuclease P activity GO:0004526 10 10 0,000 0,0101371 0,02349098 ! midbrain development GO:0030901 10 10 0,000 0,0101371 0,02347574 ! musculoskeletal movement GO:0050881 10 10 0,000 0,0101371 0,02346053 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 10 10 0,000 0,0101371 0,02344534 ! regulation of T-helper cell differentiation GO:0045622 10 10 0,000 0,0101371 0,02343016 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,0101371 0,02341501 GO:0004467|long-chain-fatty-acid-CoA ligase activity, ! regulation of mRNA stability GO:0043488 10 10 0,000 0,0101371 0,02339987 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,0101371 0,02338475 ! regulation of RNA splicing GO:0043484 10 10 0,000 0,0101371 0,02336966 ! embryonic gut development GO:0048566 10 10 0,000 0,0101371 0,02335458 ! positive regulation of amine transport GO:0051954 10 10 0,000 0,0101371 0,02333952 ! defense response to Gram-positive bacterium GO:0050830 10 10 0,000 0,0101371 0,02332448 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0101371 0,02330946 ! lysogeny GO:0030069 10 10 0,000 0,0101371 0,02329446 GO:0019047|provirus integration, ! lamellipodium assembly GO:0030032 11 10 0,000 0,0101371 0,02327948 ! regulation of synapse organization GO:0050807 10 10 0,000 0,0101371 0,02326452 ! cell wall macromolecule metabolic process GO:0044036 11 10 0,000 0,0101371 0,02324958 ! acyl-CoA binding GO:0000062 10 10 0,000 0,0101371 0,02323466 ! negative regulation of muscle development GO:0048635 11 10 0,000 0,0101371 0,02321976 GO:0045843|negative regulation of striated muscle development, ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,0101371 0,02320487 ! GDP binding GO:0019003 10 10 0,000 0,0101371 0,02319001 ! photoreceptor activity GO:0009881 10 10 0,000 0,0101371 0,02317516 ! somatic diversification of immune receptors via somatic mutation GO:0002566 10 10 0,000 0,0101371 0,02316033 GO:0016446|somatic hypermutation of immunoglobulin genes, ! cortical cytoskeleton organization GO:0030865 10 10 0,000 0,0101371 0,02314552 ! nitric-oxide synthase binding GO:0050998 11 10 0,000 0,0101371 0,02313073 ! nuclear chromosome, telomeric region GO:0000784 10 10 0,000 0,0101371 0,02311596 ! nucleotidase activity GO:0008252 10 10 0,000 0,0101371 0,02310121 ! detection of mechanical stimulus GO:0050982 10 10 0,000 0,0101371 0,02308648 ! protein complex disassembly GO:0043241 11 10 0,000 0,0101371 0,02307176 GO:0043624|cellular protein complex disassembly, ! androgen metabolic process GO:0008209 10 10 0,000 0,0101371 0,02305707 ! lateral plasma membrane GO:0016328 10 10 0,000 0,0101371 0,02304239 ! estrogen metabolic process GO:0008210 10 10 0,000 0,0101371 0,02302773 ! nucleocytoplasmic transporter activity GO:0005487 10 10 0,000 0,0101371 0,02301309 ! retinol dehydrogenase activity GO:0004745 10 10 0,000 0,0101371 0,02299847 ! negative regulation of cell-matrix adhesion GO:0001953 12 10 0,000 0,0101371 0,02298387 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 11 10 0,000 0,0101371 0,02296929 ! interleukin-1 binding GO:0019966 10 10 0,000 0,0101371 0,02295472 ! endothelial cell differentiation GO:0045446 10 10 0,000 0,0101371 0,02294018 ! cullin-RING ubiquitin ligase complex GO:0031461 10 10 0,000 0,0101371 0,02292565 ! acid phosphatase activity GO:0003993 10 10 0,000 0,0101371 0,02291114 ! regulation of stress fiber formation GO:0051492 13 10 0,000 0,0101371 0,02289665 ! sodium:potassium-exchanging ATPase activity GO:0005391 11 10 0,000 0,0101371 0,02288217 ! calcium-transporting ATPase activity GO:0005388 12 10 0,000 0,0101371 0,02286772 ! telomeric DNA binding GO:0042162 11 10 0,000 0,0101371 0,02285328 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,0101371 0,02283886 ! lipid digestion GO:0044241 10 10 0,000 0,0101371 0,02282446 ! multicellular organism growth GO:0035264 10 10 0,000 0,0101371 0,02281008 ! receptor clustering GO:0043113 10 10 0,000 0,0101371 0,02279572 ! L-glutamate transmembrane transporter activity GO:0005313 10 10 0,000 0,0101371 0,02278137 GO:0015172|acidic amino acid transmembrane transporter activity, ! brush border membrane GO:0031526 11 10 0,000 0,0101371 0,02276704 ! adult heart development GO:0007512 12 10 0,000 0,0101371 0,02275273 ! actin cytoskeleton reorganization GO:0031532 12 10 0,000 0,0101371 0,02273844 ! signalosome GO:0008180 10 10 0,000 0,0101371 0,02272417 ! prefoldin complex GO:0016272 10 10 0,000 0,0101371 0,02270991 ! neuromuscular junction GO:0031594 10 10 0,000 0,0101371 0,02269567 ! regulation of bone resorption GO:0045124 11 10 0,000 0,0101371 0,02268145 ! positive regulation of peptide secretion GO:0002793 10 10 0,000 0,0101371 0,02266725 ! alpha-beta T cell differentiation GO:0046632 11 10 0,000 0,0101371 0,02265307 ! negative regulation of myeloid leukocyte differentiation GO:0002762 10 10 0,000 0,0101371 0,0226389 ! positive regulation of T cell mediated immunity GO:0002711 14 10 0,000 0,0101371 0,02262475 ! taste receptor activity GO:0008527 10 10 0,000 0,0101371 0,02261062 ! Ran GTPase binding GO:0008536 10 10 0,000 0,0101371 0,0225965 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,0101371 0,02258241 ! regulation of interleukin-12 production GO:0032655 10 10 0,000 0,0101371 0,02256833 ! ribosome assembly GO:0042255 10 10 0,000 0,0101371 0,02255427 ! DNA methylation GO:0006306 12 10 0,000 0,0101371 0,02254022 GO:0006305|DNA alkylation, ! protein-hormone receptor activity GO:0016500 10 10 0,000 0,0101371 0,0225262 ! bile acid transmembrane transporter activity GO:0015125 10 10 0,000 0,0101371 0,02251219 ! proteasome accessory complex GO:0022624 11 10 0,000 0,0101371 0,0224982 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 13 10 0,000 0,0101371 0,02248422 ! prostaglandin receptor activity GO:0004955 11 10 0,000 0,0101371 0,02247027 ! regulation of isotype switching GO:0045191 14 10 0,000 0,0101371 0,02245633 ! peptide transporter activity GO:0015197 10 10 0,000 0,0101371 0,0224424 ! regulation of leukocyte migration GO:0002685 10 10 0,000 0,0101371 0,0224285 ! retinoid-X receptor activity GO:0004886 10 10 0,000 0,0101371 0,02241461 ! GTPase inhibitor activity GO:0005095 10 10 0,000 0,0101371 0,02240074 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,0101371 0,02238689 ! germ cell migration GO:0008354 10 10 0,000 0,0101371 0,02237305 ! regulation of organic acid transport GO:0032890 10 10 0,000 0,0101371 0,02235923 ! negative regulation of mast cell proliferation GO:0070667 10 10 0,000 0,0101371 0,02234543 GO:0042130|negative regulation of T cell proliferation, ! cardiac cell differentiation GO:0035051 11 10 0,000 0,0101371 0,02233165 ! amiloride-sensitive sodium channel activity GO:0015280 10 10 0,000 0,0101371 0,02231788 ! sterol transporter activity GO:0015248 10 10 0,000 0,0101371 0,02230413 ! regulation of embryonic development GO:0045995 11 10 0,000 0,0101371 0,02229039 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 11 11 0,000 0,01114552 0,02449271 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 11 0,000 0,01114552 0,02447765 ! negative regulation of blood pressure GO:0045776 11 11 0,000 0,01114552 0,0244626 ! RNA cap binding GO:0000339 12 11 0,000 0,01114552 0,02444758 ! CTP metabolic process GO:0046036 12 11 0,000 0,01114552 0,02443257 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 11 0,000 0,01114552 0,02441758 ! response to pain GO:0048265 11 11 0,000 0,01114552 0,02440261 ! axonemal dynein complex GO:0005858 11 11 0,000 0,01114552 0,02438766 ! eukaryotic translation initiation factor 3 complex GO:0005852 11 11 0,000 0,01114552 0,02437272 ! dopamine receptor signaling pathway GO:0007212 13 11 0,000 0,01114552 0,02435781 ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 11 0,000 0,01114552 0,02434291 ! endocrine pancreas development GO:0031018 11 11 0,000 0,01114552 0,02432803 ! regulation of interferon-gamma biosynthetic process GO:0045072 12 11 0,000 0,01114552 0,02431317 ! regulation of exit from mitosis GO:0007096 11 11 0,000 0,01114552 0,02429833 ! chylomicron GO:0042627 11 11 0,000 0,01114552 0,0242835 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 11 11 0,000 0,01114552 0,02426869 ! glycolipid biosynthetic process GO:0009247 11 11 0,000 0,01114552 0,02425391 ! transforming growth factor beta binding GO:0050431 11 11 0,000 0,01114552 0,02423913 ! glutamate metabolic process GO:0006536 12 11 0,000 0,01114552 0,02422438 ! ribonucleotide catabolic process GO:0009261 11 11 0,000 0,01114552 0,02420965 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01114552 0,02419493 ! vascular endothelial growth factor receptor activity GO:0005021 11 11 0,000 0,01114552 0,02418023 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 11 11 0,000 0,01114552 0,02416555 GO:0045125|bioactive lipid receptor activity, ! Rac GTPase binding GO:0048365 11 11 0,000 0,01114552 0,02415088 ! epithelial cell development GO:0002064 11 11 0,000 0,01114552 0,02413624 ! filamentous actin GO:0031941 11 11 0,000 0,01114552 0,02412161 ! temperature homeostasis GO:0001659 11 11 0,000 0,01114552 0,024107 ! structural constituent of epidermis GO:0030280 13 11 0,000 0,01114552 0,02409241 ! protein targeting to peroxisome GO:0006625 11 11 0,000 0,01114552 0,02407783 ! spectrin GO:0008091 11 11 0,000 0,01114552 0,02406328 ! cytoskeletal adaptor activity GO:0008093 14 11 0,000 0,01114552 0,02404874 ! negative regulation of axonogenesis GO:0050771 13 11 0,000 0,01114552 0,02403421 ! regulation of phagocytosis GO:0050764 11 11 0,000 0,01114552 0,02401971 ! nucleoside triphosphate catabolic process GO:0009143 11 11 0,000 0,01114552 0,02400522 ! synaptic vesicle exocytosis GO:0016079 12 11 0,000 0,01114552 0,02399075 ! regulation of B cell differentiation GO:0045577 15 11 0,000 0,01114552 0,0239763 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 11 11 0,000 0,01114552 0,02396187 ! basal lamina GO:0005605 12 11 0,000 0,01114552 0,02394745 ! gastrulation with mouth forming second GO:0001702 12 11 0,000 0,01114552 0,02393305 ! spinal cord motor neuron differentiation GO:0021522 11 11 0,000 0,01114552 0,02391866 ! hindbrain morphogenesis GO:0021575 13 11 0,000 0,01114552 0,0239043 ! regulation of hormone metabolic process GO:0032350 12 11 0,000 0,01114552 0,02388995 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 11 0,000 0,01114552 0,02387562 GO:0050706|regulation of interleukin-1 beta secretion, ! COPI vesicle coat GO:0030126 11 11 0,000 0,01114552 0,02386131 GO:0030663|COPI coated vesicle membrane, ! clathrin coat of trans-Golgi network vesicle GO:0030130 14 11 0,000 0,01114552 0,02384701 ! tRNA-specific ribonuclease activity GO:0004549 11 11 0,000 0,01114552 0,02383273 ! cofactor transporter activity GO:0051184 11 11 0,000 0,01114552 0,02381847 ! cobalt ion binding GO:0050897 11 11 0,000 0,01114552 0,02380422 ! pseudouridine synthase activity GO:0009982 12 11 0,000 0,01114552 0,02378999 ! aromatic amino acid family catabolic process GO:0009074 12 11 0,000 0,01114552 0,02377578 ! serine family amino acid biosynthetic process GO:0009070 11 11 0,000 0,01114552 0,02376159 ! histone deacetylase binding GO:0042826 11 11 0,000 0,01114552 0,02374741 ! thymus development GO:0048538 12 11 0,000 0,01114552 0,02373325 ! spleen development GO:0048536 12 11 0,000 0,01114552 0,02371911 ! regulation of RNA stability GO:0043487 11 11 0,000 0,01114552 0,02370498 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 12 11 0,000 0,01114552 0,02369087 ! acid-thiol ligase activity GO:0016878 11 11 0,000 0,01114552 0,02367677 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 11 11 0,000 0,01114552 0,0236627 ! blastocyst formation GO:0001825 11 11 0,000 0,01114552 0,02364864 ! cerebellar cortex development GO:0021695 12 11 0,000 0,01114552 0,0236346 ! regulation of actin filament bundle formation GO:0032231 14 11 0,000 0,01114552 0,02362057 ! ADP binding GO:0043531 11 11 0,000 0,01114552 0,02360656 ! folic acid binding GO:0005542 11 11 0,000 0,01114552 0,02359257 ! FK506 binding GO:0005528 11 11 0,000 0,01114552 0,02357859 GO:0005527|macrolide binding, ! defense response to fungus GO:0050832 11 11 0,000 0,01114552 0,02356463 ! extracellular matrix binding GO:0050840 13 11 0,000 0,01114552 0,02355069 ! microspike assembly GO:0030035 13 11 0,000 0,01114552 0,02353676 ! cytoplasmic sequestering of protein GO:0051220 11 11 0,000 0,01114552 0,02352285 ! regulation of synapse structure and activity GO:0050803 11 11 0,000 0,01114552 0,02350895 ! organ formation GO:0048645 12 11 0,000 0,01114552 0,02349508 ! embryonic hindlimb morphogenesis GO:0035116 11 11 0,000 0,01114552 0,02348121 ! embryonic forelimb morphogenesis GO:0035115 11 11 0,000 0,01114552 0,02346737 ! cellular copper ion homeostasis GO:0006878 12 11 0,000 0,01114552 0,02345354 ! glycosaminoglycan catabolic process GO:0006027 11 11 0,000 0,01114552 0,02343973 ! regulation of positive chemotaxis GO:0050926 11 11 0,000 0,01114552 0,02342593 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01114552 0,02341215 ! ion channel inhibitor activity GO:0008200 13 11 0,000 0,01114552 0,02339839 GO:0016248|channel inhibitor activity, ! positive regulation of transcription factor import into nucleus GO:0042993 12 11 0,000 0,01114552 0,02338464 ! MAP kinase kinase activity GO:0004708 11 11 0,000 0,01114552 0,02337091 GO:0004712|protein serine/threonine/tyrosine kinase activity, ! cation:amino acid symporter activity GO:0005416 11 11 0,000 0,01114552 0,02335719 ! mannosyltransferase activity GO:0000030 11 11 0,000 0,01114552 0,02334349 ! cAMP-dependent protein kinase activity GO:0004691 11 11 0,000 0,01114552 0,02332981 ! FMN binding GO:0010181 11 11 0,000 0,01114552 0,02331614 ! response to X-ray GO:0010165 12 11 0,000 0,01114552 0,02330249 ! focal adhesion formation GO:0048041 13 11 0,000 0,01114552 0,02328886 ! actin polymerization or depolymerization GO:0008154 13 11 0,000 0,01114552 0,02327524 ! substrate-bound cell migration GO:0006929 11 11 0,000 0,01114552 0,02326164 ! integrator complex GO:0032039 11 11 0,000 0,01114552 0,02324805 ! UV protection GO:0009650 11 11 0,000 0,01114552 0,02323448 ! L-glutamate transport GO:0015813 11 11 0,000 0,01114552 0,02322092 GO:0015800|acidic amino acid transport, ! retinol binding GO:0019841 11 11 0,000 0,01114552 0,02320738 ! regulation of organ growth GO:0046620 12 11 0,000 0,01114552 0,02319386 ! regulation of cytokine production during immune response GO:0002718 11 11 0,000 0,01114552 0,02318035 ! regulation of T cell mediated immunity GO:0002709 15 11 0,000 0,01114552 0,02316686 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 11 11 0,000 0,01114552 0,02315338 ! regulation of interleukin-8 production GO:0032677 12 11 0,000 0,01114552 0,02313992 ! histone acetylation GO:0016573 11 11 0,000 0,01114552 0,02312647 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 12 11 0,000 0,01114552 0,02311304 ! delayed rectifier potassium channel activity GO:0005251 11 11 0,000 0,01114552 0,02309963 ! organic cation transmembrane transporter activity GO:0015101 11 11 0,000 0,01114552 0,02308623 ! chromatin silencing GO:0006342 11 11 0,000 0,01114552 0,02307285 ! gland morphogenesis GO:0022612 12 11 0,000 0,01114552 0,02305948 ! sulfate transmembrane transporter activity GO:0015116 11 11 0,000 0,01114552 0,02304613 ! hexose transmembrane transporter activity GO:0015149 11 11 0,000 0,01114552 0,02303279 ! icosanoid receptor activity GO:0004953 12 11 0,000 0,01114552 0,02301947 GO:0004954|prostanoid receptor activity, ! non-G-protein coupled 7TM receptor activity GO:0004926 12 11 0,000 0,01114552 0,02300616 ! negative regulation of neurological system process GO:0031645 12 11 0,000 0,01114552 0,02299287 ! acid secretion GO:0046717 11 11 0,000 0,01114552 0,02297959 ! nitric oxide mediated signal transduction GO:0007263 11 11 0,000 0,01114552 0,02296633 ! thyroid hormone metabolic process GO:0042403 11 11 0,000 0,01114552 0,02295309 ! quinone cofactor metabolic process GO:0042375 12 11 0,000 0,01114552 0,02293986 ! insulin-like growth factor receptor binding GO:0005159 12 11 0,000 0,01114552 0,02292665 ! midbody GO:0030496 11 11 0,000 0,01114552 0,02291345 ! interferon-alpha/beta receptor binding GO:0005132 11 11 0,000 0,01114552 0,02290026 ! cAMP-dependent protein kinase complex GO:0005952 11 11 0,000 0,01114552 0,02288709 ! water channel activity GO:0015250 11 11 0,000 0,01114552 0,02287394 ! response to nicotine GO:0035094 11 11 0,000 0,01114552 0,0228608 ! response to cold GO:0009409 11 11 0,000 0,01114552 0,02284768 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01114552 0,02283457 ! 'de novo' protein folding GO:0006458 12 12 0,000 0,01215298 0,02488434 ! centriole GO:0005814 12 12 0,000 0,01215298 0,02487008 ! organellar large ribosomal subunit GO:0000315 13 12 0,000 0,01215298 0,02485584 GO:0005762|mitochondrial large ribosomal subunit, ! cadmium ion binding GO:0046870 13 12 0,000 0,01215298 0,02484161 ! folic acid and derivative biosynthetic process GO:0009396 12 12 0,000 0,01215298 0,0248274 ! bone remodeling GO:0046849 12 12 0,000 0,01215298 0,0248132 ! peroxisomal transport GO:0043574 12 12 0,000 0,01215298 0,02479903 ! retina development in camera-type eye GO:0060041 13 12 0,000 0,01215298 0,02478486 ! hair follicle morphogenesis GO:0031069 12 12 0,000 0,01215298 0,02477072 ! voltage-gated sodium channel complex GO:0001518 13 12 0,000 0,01215298 0,02475659 GO:0034706|sodium channel complex, ! regulation of excitatory postsynaptic membrane potential GO:0060079 14 12 0,000 0,01215298 0,02474247 ! hippocampus development GO:0021766 12 12 0,000 0,01215298 0,02472837 ! T cell selection GO:0045058 16 12 0,000 0,01215298 0,02471429 ! cation:cation antiporter activity GO:0015491 12 12 0,000 0,01215298 0,02470022 ! induction of apoptosis via death domain receptors GO:0008625 12 12 0,000 0,01215298 0,02468617 ! T-tubule GO:0030315 13 12 0,000 0,01215298 0,02467214 ! methionine metabolic process GO:0006555 13 12 0,000 0,01215298 0,02465812 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 14 12 0,000 0,01215298 0,02464412 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! peptide antigen binding GO:0042605 12 12 0,000 0,01215298 0,02463013 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,01215298 0,02461616 ! cell-cell junction assembly GO:0007043 12 12 0,000 0,01215298 0,02460221 ! mitotic spindle organization GO:0007052 12 12 0,000 0,01215298 0,02458827 ! fear response GO:0042596 12 12 0,000 0,01215298 0,02457435 ! negative regulation of mitotic cell cycle GO:0045930 13 12 0,000 0,01215298 0,02456044 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,01215298 0,02454655 ! copper ion homeostasis GO:0055070 13 12 0,000 0,01215298 0,02453267 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,01215298 0,02451881 ! axon cargo transport GO:0008088 12 12 0,000 0,01215298 0,02450497 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 13 12 0,000 0,01215298 0,02449114 ! transcription elongation factor complex GO:0008023 13 12 0,000 0,01215298 0,02447732 ! positive regulation of Ras GTPase activity GO:0032320 12 12 0,000 0,01215298 0,02446353 ! nuclear outer membrane GO:0005640 12 12 0,000 0,01215298 0,02444974 ! beta-tubulin binding GO:0048487 12 12 0,000 0,01215298 0,02443598 ! autonomic nervous system development GO:0048483 12 12 0,000 0,01215298 0,02442223 ! positive regulation of interleukin-1 secretion GO:0050716 12 12 0,000 0,01215298 0,02440849 GO:0050704|regulation of interleukin-1 secretion, ! exoribonuclease activity GO:0004532 12 12 0,000 0,01215298 0,02439477 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! cofactor transport GO:0051181 12 12 0,000 0,01215298 0,02438106 ! regulation of epidermis development GO:0045682 12 12 0,000 0,01215298 0,02436737 ! protein-chromophore linkage GO:0018298 12 12 0,000 0,01215298 0,0243537 ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 12 12 0,000 0,01215298 0,02434004 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 12 0,000 0,01215298 0,0243264 ! lymphocyte homeostasis GO:0002260 14 12 0,000 0,01215298 0,02431277 ! regulation of fatty acid oxidation GO:0046320 13 12 0,000 0,01215298 0,02429916 ! detection of bacterium GO:0016045 13 12 0,000 0,01215298 0,02428556 ! positive regulation of neuron apoptosis GO:0043525 12 12 0,000 0,01215298 0,02427198 ! dystrophin-associated glycoprotein complex GO:0016010 14 12 0,000 0,01215298 0,02425841 ! internal side of plasma membrane GO:0009898 14 12 0,000 0,01215298 0,02424486 ! RNA 3'-end processing GO:0031123 12 12 0,000 0,01215298 0,02423132 ! developmental induction GO:0031128 13 12 0,000 0,01215298 0,0242178 GO:0045168|cell-cell signaling involved in cell fate specification, ! fibrillar collagen GO:0005583 13 12 0,000 0,01215298 0,02420429 ! positive regulation of calcium-mediated signaling GO:0050850 14 12 0,000 0,01215298 0,0241908 ! inner ear receptor cell differentiation GO:0060113 13 12 0,000 0,01215298 0,02417732 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,01215298 0,02416386 ! very-long-chain fatty acid metabolic process GO:0000038 12 12 0,000 0,01215298 0,02415041 ! negative regulation of cell projection organization GO:0031345 14 12 0,000 0,01215298 0,02413698 ! thyroid gland development GO:0030878 12 12 0,000 0,01215298 0,02412357 ! non-recombinational repair GO:0000726 12 12 0,000 0,01215298 0,02411016 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 12 12 0,000 0,01215298 0,02409678 ! lipid localization GO:0010876 12 12 0,000 0,01215298 0,0240834 GO:0019915|lipid storage, ! regulation of glycolysis GO:0006110 12 12 0,000 0,01215298 0,02407005 ! response to cAMP GO:0051591 12 12 0,000 0,01215298 0,0240567 ! negative regulation of transcription factor import into nucleus GO:0042992 12 12 0,000 0,01215298 0,02404338 ! T cell proliferation GO:0042098 17 12 0,000 0,01215298 0,02403006 ! negative regulation of protein amino acid phosphorylation GO:0001933 16 12 0,000 0,01215298 0,02401676 ! receptor signaling protein tyrosine kinase activity GO:0004716 13 12 0,000 0,01215298 0,02400348 ! two-component signal transduction system (phosphorelay) GO:0000160 13 12 0,000 0,01215298 0,02399021 ! peptide or protein amino-terminal blocking GO:0018409 13 12 0,000 0,01215298 0,02397696 ! drug transport GO:0015893 12 12 0,000 0,01215298 0,02396372 ! GTP-dependent protein binding GO:0030742 12 12 0,000 0,01215298 0,02395049 ! regulation of interleukin-6 biosynthetic process GO:0045408 12 12 0,000 0,01215298 0,02393728 ! T cell receptor complex GO:0042101 12 12 0,000 0,01215298 0,02392409 ! membrane protein proteolysis GO:0033619 13 12 0,000 0,01215298 0,02391091 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of caspase activity GO:0043154 12 12 0,000 0,01215298 0,02389774 ! protein disulfide oxidoreductase activity GO:0015035 12 12 0,000 0,01215298 0,02388459 ! histone acetyltransferase complex GO:0000123 13 12 0,000 0,01215298 0,02387145 ! dendritic spine GO:0043197 12 12 0,000 0,01215298 0,02385833 ! ATP-binding cassette (ABC) transporter complex GO:0043190 12 12 0,000 0,01215298 0,02384522 ! alpha-beta T cell activation GO:0046631 13 12 0,000 0,01215298 0,02383212 ! organic anion transmembrane transporter activity GO:0008514 13 12 0,000 0,01215298 0,02381904 ! vasoconstriction GO:0042310 13 12 0,000 0,01215298 0,02380598 ! DNA unwinding during replication GO:0006268 12 12 0,000 0,01215298 0,02379292 ! cellular amino acid derivative catabolic process GO:0042219 16 12 0,000 0,01215298 0,02377989 ! mRNA splice site selection GO:0006376 13 12 0,000 0,01215298 0,02376686 ! phosphate transmembrane transporter activity GO:0015114 13 12 0,000 0,01215298 0,02375386 ! trans-Golgi network transport vesicle membrane GO:0012510 15 12 0,000 0,01215298 0,02374086 ! ubiquitin protein ligase binding GO:0031625 12 12 0,000 0,01215298 0,02372788 ! monosaccharide transmembrane transporter activity GO:0015145 12 12 0,000 0,01215298 0,02371491 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 12 12 0,000 0,01215298 0,02370196 ! hexosaminidase activity GO:0015929 12 12 0,000 0,01215298 0,02368903 ! diacylglycerol kinase activity GO:0004143 13 12 0,000 0,01215298 0,0236761 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,01215298 0,02366319 ! activation of NF-kappaB-inducing kinase activity GO:0007250 12 12 0,000 0,01215298 0,0236503 ! protein kinase C binding GO:0005080 13 12 0,000 0,01215298 0,02363741 ! catecholamine biosynthetic process GO:0042423 13 12 0,000 0,01215298 0,02362455 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 15 12 0,000 0,01215298 0,02361169 ! L-fucose metabolic process GO:0042354 14 12 0,000 0,01215298 0,02359885 ! acylglycerol O-acyltransferase activity GO:0016411 12 12 0,000 0,01215298 0,02358603 ! C-acyltransferase activity GO:0016408 12 12 0,000 0,01215298 0,02357322 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,01215298 0,02356042 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01215298 0,02354764 ! calcium-activated potassium channel activity GO:0015269 14 12 0,000 0,01215298 0,02353487 ! SWI/SNF-type complex GO:0070603 13 12 0,000 0,01215298 0,02352211 GO:0016514|SWI/SNF complex, ! positive regulation of translation GO:0045727 13 13 0,000 0,01315948 0,0254564 ! ER-associated protein catabolic process GO:0030433 13 13 0,000 0,01315948 0,02544261 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01315948 0,02542885 ! superoxide anion generation GO:0042554 13 13 0,000 0,01315948 0,02541509 ! pteridine and derivative biosynthetic process GO:0042559 14 13 0,000 0,01315948 0,02540136 ! cis-Golgi network GO:0005801 14 13 0,000 0,01315948 0,02538763 ! regulation of S phase GO:0033261 17 13 0,000 0,01315948 0,02537392 ! regulation of chemokine production GO:0032642 13 13 0,000 0,01315948 0,02536023 ! phospholipid catabolic process GO:0009395 14 13 0,000 0,01315948 0,02534655 ! positive regulation of GTPase activity GO:0043547 14 13 0,000 0,01315948 0,02533289 ! endothelial cell migration GO:0043542 13 13 0,000 0,01315948 0,02531924 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 13 13 0,000 0,01315948 0,0253056 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01315948 0,02529199 ! cartilage condensation GO:0001502 14 13 0,000 0,01315948 0,02527838 ! organelle fusion GO:0048284 14 13 0,000 0,01315948 0,02526479 ! positive regulation of lipid metabolic process GO:0045834 13 13 0,000 0,01315948 0,02525121 ! pseudouridine synthesis GO:0001522 14 13 0,000 0,01315948 0,02523765 ! negative regulation of gene expression, epigenetic GO:0045814 13 13 0,000 0,01315948 0,02522411 ! positive regulation of cell growth GO:0030307 13 13 0,000 0,01315948 0,02521057 ! regulation of interleukin-2 biosynthetic process GO:0045076 13 13 0,000 0,01315948 0,02519706 ! negative regulation of proteolysis GO:0045861 13 13 0,000 0,01315948 0,02518355 ! regulation of mRNA processing GO:0050684 13 13 0,000 0,01315948 0,02517006 ! arginine metabolic process GO:0006525 13 13 0,000 0,01315948 0,02515659 ! WW domain binding GO:0050699 14 13 0,000 0,01315948 0,02514313 ! cholesterol binding GO:0015485 13 13 0,000 0,01315948 0,02512968 ! negative regulation of microtubule depolymerization GO:0007026 15 13 0,000 0,01315948 0,02511625 GO:0031114|regulation of microtubule depolymerization, ! Golgi organization GO:0007030 16 13 0,000 0,01315948 0,02510284 ! negative regulation of endothelial cell migration GO:0010596 13 13 0,000 0,01315948 0,02508943 ! integral to peroxisomal membrane GO:0005779 13 13 0,000 0,01315948 0,02507605 GO:0031231|intrinsic to peroxisomal membrane, ! integral to membrane of membrane fraction GO:0000299 14 13 0,000 0,01315948 0,02506267 ! regulation of heart rate GO:0002027 14 13 0,000 0,01315948 0,02504931 ! positive regulation of carbohydrate metabolic process GO:0045913 14 13 0,000 0,01315948 0,02503597 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cotranslational protein targeting to membrane GO:0006613 14 13 0,000 0,01315948 0,02502263 ! negative regulation of immune response GO:0050777 17 13 0,000 0,01315948 0,02500932 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 13 0,000 0,01315948 0,02499602 ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01315948 0,02498273 ! response to estradiol stimulus GO:0032355 14 13 0,000 0,01315948 0,02496945 ! anaphase-promoting complex GO:0005680 13 13 0,000 0,01315948 0,02495619 ! nucleotide diphosphatase activity GO:0004551 13 13 0,000 0,01315948 0,02494294 ! NADP metabolic process GO:0006739 13 13 0,000 0,01315948 0,02492971 ! regulation of erythrocyte differentiation GO:0045646 13 13 0,000 0,01315948 0,02491649 ! intestinal absorption GO:0050892 13 13 0,000 0,01315948 0,02490329 ! eukaryotic cell surface binding GO:0043499 14 13 0,000 0,01315948 0,0248901 ! digestive tract morphogenesis GO:0048546 13 13 0,000 0,01315948 0,02487692 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 14 13 0,000 0,01315948 0,02486376 ! regulation of cellular carbohydrate catabolic process GO:0043471 14 13 0,000 0,01315948 0,02485061 GO:0043470|regulation of carbohydrate catabolic process, ! tropomyosin binding GO:0005523 13 13 0,000 0,01315948 0,02483748 ! carbon-sulfur lyase activity GO:0016846 13 13 0,000 0,01315948 0,02482436 ! embryonic placenta development GO:0001892 13 13 0,000 0,01315948 0,02481125 ! positive regulation of protein polymerization GO:0032273 13 13 0,000 0,01315948 0,02479816 ! insulin secretion GO:0030073 13 13 0,000 0,01315948 0,02478508 ! positive regulation of cellular catabolic process GO:0031331 14 13 0,000 0,01315948 0,02477201 ! G1 phase of mitotic cell cycle GO:0000080 13 13 0,000 0,01315948 0,02475896 ! replisome GO:0030894 14 13 0,000 0,01315948 0,02474592 GO:0043601|nuclear replisome, ! regulation of nitric-oxide synthase activity GO:0050999 13 13 0,000 0,01315948 0,0247329 ! copper ion transport GO:0006825 13 13 0,000 0,01315948 0,02471989 ! regulation of cell-cell adhesion GO:0022407 13 13 0,000 0,01315948 0,02470689 ! forelimb morphogenesis GO:0035136 13 13 0,000 0,01315948 0,02469391 ! mating GO:0007618 13 13 0,000 0,01315948 0,02468094 ! phosphatidylinositol phosphate kinase activity GO:0016307 14 13 0,000 0,01315948 0,02466798 ! MAP kinase activity GO:0004707 14 13 0,000 0,01315948 0,02465504 ! cytokine biosynthetic process GO:0042089 13 13 0,000 0,01315948 0,02464211 ! ventral spinal cord development GO:0021517 13 13 0,000 0,01315948 0,0246292 ! prenyltransferase activity GO:0004659 14 13 0,000 0,01315948 0,0246163 ! platelet-derived growth factor receptor signaling pathway GO:0048008 15 13 0,000 0,01315948 0,02460341 ! regulation of skeletal muscle fiber development GO:0048742 13 13 0,000 0,01315948 0,02459053 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 15 13 0,000 0,01315948 0,02457767 ! protein kinase C activity GO:0004697 15 13 0,000 0,01315948 0,02456482 ! oligodendrocyte differentiation GO:0048709 13 13 0,000 0,01315948 0,02455199 ! water transporter activity GO:0005372 13 13 0,000 0,01315948 0,02453917 ! exocrine system development GO:0035272 14 13 0,000 0,01315948 0,02452636 ! dicarboxylic acid transmembrane transporter activity GO:0005310 13 13 0,000 0,01315948 0,02451357 ! monoamine transport GO:0015844 13 13 0,000 0,01315948 0,02450079 ! CoA hydrolase activity GO:0016289 13 13 0,000 0,01315948 0,02448802 ! embryo implantation GO:0007566 13 13 0,000 0,01315948 0,02447526 ! G1/S transition checkpoint GO:0031575 13 13 0,000 0,01315948 0,02446252 ! positive regulation of alpha-beta T cell differentiation GO:0046638 13 13 0,000 0,01315948 0,0244498 ! immunoglobulin binding GO:0019865 13 13 0,000 0,01315948 0,02443708 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01315948 0,02442438 ! anchored to plasma membrane GO:0046658 14 13 0,000 0,01315948 0,02441169 ! histone deacetylation GO:0016575 13 13 0,000 0,01315948 0,02439902 ! calcium channel regulator activity GO:0005246 14 13 0,000 0,01315948 0,02438636 ! neuroblast proliferation GO:0007405 13 13 0,000 0,01315948 0,02437371 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01315948 0,02436107 ! response to gamma radiation GO:0010332 13 13 0,000 0,01315948 0,02434845 ! sarcomere organization GO:0045214 13 13 0,000 0,01315948 0,02433584 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 15 13 0,000 0,01315948 0,02432324 ! cAMP binding GO:0030552 13 13 0,000 0,01315948 0,02431066 ! fucosyltransferase activity GO:0008417 14 13 0,000 0,01315948 0,02429809 ! cilium assembly GO:0042384 13 13 0,000 0,01315948 0,02428553 ! negative regulation of leukocyte proliferation GO:0070664 13 13 0,000 0,01315948 0,02427299 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! bacterial binding GO:0008367 13 13 0,000 0,01315948 0,02426046 ! regulation of NF-kappaB import into nucleus GO:0042345 13 13 0,000 0,01315948 0,02424794 ! acrosome reaction GO:0007340 13 13 0,000 0,01315948 0,02423543 ! microtubule-based flagellum GO:0009434 13 13 0,000 0,01315948 0,02422294 ! nucleolar part GO:0044452 13 13 0,000 0,01315948 0,02421046 ! axoneme part GO:0044447 13 13 0,000 0,01315948 0,024198 ! tRNA modification GO:0006400 14 14 0,000 0,01416503 0,02603361 ! positive regulation of blood pressure GO:0045777 15 14 0,000 0,01416503 0,02602022 ! transferase activity, transferring amino-acyl groups GO:0016755 14 14 0,000 0,01416503 0,02600684 ! negative regulation of bone remodeling GO:0046851 14 14 0,000 0,01416503 0,02599348 ! 2'-deoxyribonucleotide metabolic process GO:0009394 15 14 0,000 0,01416503 0,02598013 GO:0019692|deoxyribose phosphate metabolic process, ! transcription from RNA polymerase III promoter GO:0006383 14 14 0,000 0,01416503 0,02596679 ! striated muscle thin filament GO:0005865 15 14 0,000 0,01416503 0,02595347 ! patterning of blood vessels GO:0001569 14 14 0,000 0,01416503 0,02594016 ! mechanoreceptor differentiation GO:0042490 15 14 0,000 0,01416503 0,02592686 ! palate development GO:0060021 15 14 0,000 0,01416503 0,02591358 ! regulation of defense response to virus GO:0050688 14 14 0,000 0,01416503 0,02590031 ! cAMP-dependent protein kinase regulator activity GO:0008603 14 14 0,000 0,01416503 0,02588705 ! ephrin receptor activity GO:0005003 16 14 0,000 0,01416503 0,02587381 ! protein polyubiquitination GO:0000209 15 14 0,000 0,01416503 0,02586059 ! glycine metabolic process GO:0006544 15 14 0,000 0,01416503 0,02584737 ! plasma membrane organization GO:0007009 14 14 0,000 0,01416503 0,02583417 ! tyrosine metabolic process GO:0006570 16 14 0,000 0,01416503 0,02582098 ! response to retinoic acid GO:0032526 14 14 0,000 0,01416503 0,02580781 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 16 14 0,000 0,01416503 0,02579465 ! lysosomal transport GO:0007041 14 14 0,000 0,01416503 0,0257815 ! rough endoplasmic reticulum GO:0005791 14 14 0,000 0,01416503 0,02576837 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 14 14 0,000 0,01416503 0,02575525 ! regulation of the force of heart contraction GO:0002026 15 14 0,000 0,01416503 0,02574214 ! bone mineralization GO:0030282 14 14 0,000 0,01416503 0,02572905 ! protein kinase activator activity GO:0030295 14 14 0,000 0,01416503 0,02571597 ! NLS-bearing substrate import into nucleus GO:0006607 15 14 0,000 0,01416503 0,0257029 ! cerebellum development GO:0021549 15 14 0,000 0,01416503 0,02568984 ! G1 phase GO:0051318 14 14 0,000 0,01416503 0,0256768 ! negative regulation of blood coagulation GO:0030195 16 14 0,000 0,01416503 0,02566378 ! negative regulation of protein secretion GO:0050709 14 14 0,000 0,01416503 0,02565076 ! water homeostasis GO:0030104 14 14 0,000 0,01416503 0,02563776 ! peptide hormone binding GO:0017046 14 14 0,000 0,01416503 0,02562477 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,01416503 0,0256118 ! glutamine family amino acid biosynthetic process GO:0009084 15 14 0,000 0,01416503 0,02559884 ! regulation of ATPase activity GO:0043462 15 14 0,000 0,01416503 0,02558589 ! racemase and epimerase activity GO:0016854 14 14 0,000 0,01416503 0,02557295 ! regulation of leukocyte mediated cytotoxicity GO:0001910 18 14 0,000 0,01416503 0,02556003 ! release of cytochrome c from mitochondria GO:0001836 14 14 0,000 0,01416503 0,02554712 ! positive regulation of calcium ion transport GO:0051928 17 14 0,000 0,01416503 0,02553423 ! regulation of blood vessel endothelial cell migration GO:0043535 14 14 0,000 0,01416503 0,02552134 ! regulation of calcium-mediated signaling GO:0050848 16 14 0,000 0,01416503 0,02550847 ! positive regulation of synaptic transmission GO:0050806 14 14 0,000 0,01416503 0,02549562 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 16 14 0,000 0,01416503 0,02548277 ! lactation GO:0007595 15 14 0,000 0,01416503 0,02546994 ! reproductive cellular process GO:0048610 14 14 0,000 0,01416503 0,02545712 ! positive regulation of cell killing GO:0031343 18 14 0,000 0,01416503 0,02544432 ! sulfur amino acid biosynthetic process GO:0000097 15 14 0,000 0,01416503 0,02543153 ! dicarboxylic acid transport GO:0006835 14 14 0,000 0,01416503 0,02541875 ! inorganic anion exchanger activity GO:0005452 15 14 0,000 0,01416503 0,02540598 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 15 14 0,000 0,01416503 0,02539323 ! negative regulation of cytokine biosynthetic process GO:0042036 14 14 0,000 0,01416503 0,02538048 ! negative regulation of ion transport GO:0043271 14 14 0,000 0,01416503 0,02536776 ! retinoic acid receptor binding GO:0042974 14 14 0,000 0,01416503 0,02535504 ! startle response GO:0001964 14 14 0,000 0,01416503 0,02534234 ! 2 iron, 2 sulfur cluster binding GO:0051537 14 14 0,000 0,01416503 0,02532965 ! activation of MAPKK activity GO:0000186 15 14 0,000 0,01416503 0,02531697 ! response to hexose stimulus GO:0009746 14 14 0,000 0,01416503 0,0253043 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! cytokine metabolic process GO:0042107 14 14 0,000 0,01416503 0,02529165 ! organic alcohol transport GO:0015850 15 14 0,000 0,01416503 0,02527901 ! preassembly of GPI anchor in ER membrane GO:0016254 15 14 0,000 0,01416503 0,02526639 ! calcium ion transmembrane transporter activity GO:0015085 16 14 0,000 0,01416503 0,02525377 ! eukaryotic translation initiation factor 4F complex GO:0016281 14 14 0,000 0,01416503 0,02524117 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,01416503 0,02522858 ! L-amino acid transport GO:0015807 14 14 0,000 0,01416503 0,025216 ! microfilament motor activity GO:0000146 14 14 0,000 0,01416503 0,02520344 ! stem cell development GO:0048864 14 14 0,000 0,01416503 0,02519089 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 15 14 0,000 0,01416503 0,02517835 ! DNA replication initiation GO:0006270 14 14 0,000 0,01416503 0,02516582 ! T cell differentiation in the thymus GO:0033077 18 14 0,000 0,01416503 0,02515331 ! regulation of cellular pH GO:0030641 14 14 0,000 0,01416503 0,02514081 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,01416503 0,02512832 ! calcium activated cation channel activity GO:0005227 16 14 0,000 0,01416503 0,02511584 ! sulfuric ester hydrolase activity GO:0008484 15 14 0,000 0,01416503 0,02510338 ! serotonin receptor activity GO:0004993 14 14 0,000 0,01416503 0,02509092 ! positive regulation of bone mineralization GO:0030501 15 14 0,000 0,01416503 0,02507849 ! synaptic transmission, cholinergic GO:0007271 15 14 0,000 0,01416503 0,02506606 ! dopamine metabolic process GO:0042417 17 14 0,000 0,01416503 0,02505364 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,01416503 0,02504124 ! ion gated channel activity GO:0022839 16 14 0,000 0,01416503 0,02502885 ! male genitalia development GO:0030539 14 14 0,000 0,01416503 0,02501647 ! regulation of axon extension GO:0030516 15 14 0,000 0,01416503 0,02500411 ! regulation of BMP signaling pathway GO:0030510 14 14 0,000 0,01416503 0,02499175 ! estrogen receptor signaling pathway GO:0030520 14 14 0,000 0,01416503 0,02497941 ! interleukin-1 receptor binding GO:0005149 14 14 0,000 0,01416503 0,02496708 ! defense response to virus GO:0051607 19 14 0,000 0,01416503 0,02495476 ! cadherin binding GO:0045296 16 14 0,000 0,01416503 0,02494246 ! negative regulation of hormone secretion GO:0046888 16 15 0,000 0,01516961 0,02669822 ! nuclear replication fork GO:0043596 16 15 0,000 0,01516961 0,02668507 ! skin development GO:0043588 16 15 0,000 0,01516961 0,02667193 ! phosphoinositide phosphorylation GO:0046854 16 15 0,000 0,01516961 0,0266588 GO:0046834|lipid phosphorylation, ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01516961 0,02664569 ! cardiac muscle contraction GO:0060048 16 15 0,000 0,01516961 0,02663259 ! polysome GO:0005844 16 15 0,000 0,01516961 0,0266195 ! negative regulation of peptidase activity GO:0010466 16 15 0,000 0,01516961 0,02660643 ! mitotic chromosome condensation GO:0007076 15 15 0,000 0,01516961 0,02659337 ! regulation of viral genome replication GO:0045069 15 15 0,000 0,01516961 0,02658032 ! regulation of survival gene product expression GO:0045884 15 15 0,000 0,01516961 0,02656728 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 15 0,000 0,01516961 0,02655426 ! glycoprotein catabolic process GO:0006516 15 15 0,000 0,01516961 0,02654125 ! DNA duplex unwinding GO:0032508 15 15 0,000 0,01516961 0,02652825 GO:0032392|DNA geometric change, ! glutamine metabolic process GO:0006541 16 15 0,000 0,01516961 0,02651526 ! proton-transporting V-type ATPase complex GO:0033176 15 15 0,000 0,01516961 0,02650229 ! response to vitamin A GO:0033189 15 15 0,000 0,01516961 0,02648933 ! protease binding GO:0002020 16 15 0,000 0,01516961 0,02647639 ! regulation of ion transmembrane transporter activity GO:0032412 15 15 0,000 0,01516961 0,02646345 ! actin filament bundle formation GO:0051017 15 15 0,000 0,01516961 0,02645053 ! calcium ion-dependent exocytosis GO:0017156 15 15 0,000 0,01516961 0,02643762 ! purine nucleoside monophosphate metabolic process GO:0009126 16 15 0,000 0,01516961 0,02642472 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! protein export from nucleus GO:0006611 15 15 0,000 0,01516961 0,02641184 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01516961 0,02639897 ! positive regulation of biomineral formation GO:0070169 16 15 0,000 0,01516961 0,02638611 ! positive regulation of oxidoreductase activity GO:0051353 15 15 0,000 0,01516961 0,02637326 ! filopodium GO:0030175 15 15 0,000 0,01516961 0,02636043 ! negative regulation of inflammatory response GO:0050728 15 15 0,000 0,01516961 0,02634761 ! positive regulation of transmission of nerve impulse GO:0051971 15 15 0,000 0,01516961 0,0263348 ! branched chain family amino acid metabolic process GO:0009081 15 15 0,000 0,01516961 0,026322 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01516961 0,02630922 ! heme biosynthetic process GO:0006783 15 15 0,000 0,01516961 0,02629645 ! SMAD binding GO:0046332 16 15 0,000 0,01516961 0,02628369 ! nerve development GO:0021675 16 15 0,000 0,01516961 0,02627094 ! epithelial to mesenchymal transition GO:0001837 16 15 0,000 0,01516961 0,02625821 ! mannose binding GO:0005537 15 15 0,000 0,01516961 0,02624549 ! phosphoprotein binding GO:0051219 17 15 0,000 0,01516961 0,02623278 ! mismatched DNA binding GO:0030983 15 15 0,000 0,01516961 0,02622008 ! antigen receptor-mediated signaling pathway GO:0050851 21 15 0,000 0,01516961 0,0262074 ! regulation of skeletal muscle tissue development GO:0048641 15 15 0,000 0,01516961 0,02619472 ! synaptonemal complex GO:0000795 15 15 0,000 0,01516961 0,02618206 ! N-terminal protein amino acid modification GO:0031365 16 15 0,000 0,01516961 0,02616941 ! positive regulation of protein complex assembly GO:0031334 15 15 0,000 0,01516961 0,02615678 ! water transport GO:0006833 15 15 0,000 0,01516961 0,02614415 GO:0042044|fluid transport, ! phosphatidylinositol metabolic process GO:0046488 16 15 0,000 0,01516961 0,02613154 ! viral genome replication GO:0019079 15 15 0,000 0,01516961 0,02611894 ! phosphatidylcholine metabolic process GO:0046470 17 15 0,000 0,01516961 0,02610635 ! inositol metabolic process GO:0006020 15 15 0,000 0,01516961 0,02609378 ! sulfate transport GO:0008272 15 15 0,000 0,01516961 0,02608122 ! protein-lipid complex GO:0032994 15 15 0,000 0,01516961 0,02606866 GO:0034358|plasma lipoprotein particle, ! positive regulation of ion transport GO:0043270 18 15 0,000 0,01516961 0,02605613 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 15 15 0,000 0,01516961 0,0260436 ! heart looping GO:0001947 15 15 0,000 0,01516961 0,02603108 ! isoprenoid biosynthetic process GO:0008299 16 15 0,000 0,01516961 0,02601858 ! protein histidine kinase activity GO:0004673 16 15 0,000 0,01516961 0,02600609 GO:0000155|two-component sensor activity, ! cardiac muscle tissue development GO:0048738 15 15 0,000 0,01516961 0,02599361 ! regulation of striated muscle contraction GO:0006942 16 15 0,000 0,01516961 0,02598114 ! response to osmotic stress GO:0006970 16 15 0,000 0,01516961 0,02596869 ! vesicle coating GO:0006901 16 15 0,000 0,01516961 0,02595625 ! DNA integration GO:0015074 16 15 0,000 0,01516961 0,02594382 ! alcohol binding GO:0043178 16 15 0,000 0,01516961 0,0259314 ! disulfide oxidoreductase activity GO:0015036 15 15 0,000 0,01516961 0,02591899 ! intermediate filament cytoskeleton organization GO:0045104 16 15 0,000 0,01516961 0,02590659 ! regulation of vasodilation GO:0042312 15 15 0,000 0,01516961 0,02589421 ! genitalia development GO:0048806 15 15 0,000 0,01516961 0,02588184 ! structural constituent of eye lens GO:0005212 15 15 0,000 0,01516961 0,02586948 ! regulation of monooxygenase activity GO:0032768 15 15 0,000 0,01516961 0,02585713 ! voltage-gated sodium channel activity GO:0005248 17 15 0,000 0,01516961 0,02584479 ! ribonucleoprotein binding GO:0043021 16 15 0,000 0,01516961 0,02583247 ! proton-transporting ATP synthase complex GO:0045259 15 15 0,000 0,01516961 0,02582016 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 15 15 0,000 0,01516961 0,02580785 ! regulation of immunoglobulin production GO:0002637 19 15 0,000 0,01516961 0,02579556 ! retinoic acid receptor activity GO:0003708 15 15 0,000 0,01516961 0,02578329 ! receptor activator activity GO:0030546 15 15 0,000 0,01516961 0,02577102 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 15 15 0,000 0,01516961 0,02575877 ! protein transmembrane transporter activity GO:0008320 15 15 0,000 0,01516961 0,02574652 ! histone binding GO:0042393 15 15 0,000 0,01516961 0,02573429 ! phosphoinositide 3-kinase activity GO:0035004 16 15 0,000 0,01516961 0,02572207 ! sialyltransferase activity GO:0008373 15 15 0,000 0,01516961 0,02570987 ! platelet-derived growth factor receptor binding GO:0005161 16 15 0,000 0,01516961 0,02569767 ! drug transporter activity GO:0015238 15 15 0,000 0,01516961 0,02568548 ! negative regulation of homeostatic process GO:0032845 15 15 0,000 0,01516961 0,02567331 ! phosphoinositide 3-kinase complex GO:0005942 16 15 0,000 0,01516961 0,02566115 ! binding of sperm to zona pellucida GO:0007339 16 15 0,000 0,01516961 0,025649 ! peptide hormone processing GO:0016486 17 15 0,000 0,01516961 0,02563686 ! aldo-keto reductase activity GO:0004033 15 15 0,000 0,01516961 0,02562473 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01516961 0,02561262 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 16 16 0,000 0,01617324 0,02729426 ! positive regulation of cell size GO:0045793 16 16 0,000 0,01617324 0,02728137 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01617324 0,02726849 ! positive regulation of hormone secretion GO:0046887 17 16 0,000 0,01617324 0,02725562 ! protein amino acid ADP-ribosylation GO:0006471 18 16 0,000 0,01617324 0,02724276 ! response to vitamin GO:0033273 16 16 0,000 0,01617324 0,02722992 ! gene silencing by RNA GO:0031047 16 16 0,000 0,01617324 0,02721709 ! regulation of postsynaptic membrane potential GO:0060078 18 16 0,000 0,01617324 0,02720427 ! cornified envelope GO:0001533 18 16 0,000 0,01617324 0,02719146 ! regulation of transmembrane transporter activity GO:0022898 16 16 0,000 0,01617324 0,02717866 GO:0032409|regulation of transporter activity, ! negative regulation of epithelial cell proliferation GO:0050680 17 16 0,000 0,01617324 0,02716588 ! pyrimidine ribonucleotide metabolic process GO:0009218 18 16 0,000 0,01617324 0,02715311 ! pituitary gland development GO:0021983 16 16 0,000 0,01617324 0,02714035 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 18 16 0,000 0,01617324 0,0271276 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 19 16 0,000 0,01617324 0,02711486 ! cell-substrate junction assembly GO:0007044 18 16 0,000 0,01617324 0,02710214 ! peptidyl-serine phosphorylation GO:0018105 16 16 0,000 0,01617324 0,02708943 ! branching involved in ureteric bud morphogenesis GO:0001658 16 16 0,000 0,01617324 0,02707673 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 16 16 0,000 0,01617324 0,02706404 ! nucleobase metabolic process GO:0009112 19 16 0,000 0,01617324 0,02705136 ! beta-catenin binding GO:0008013 17 16 0,000 0,01617324 0,0270387 ! regulation of steroid metabolic process GO:0019218 17 16 0,000 0,01617324 0,02702604 ! neuron recognition GO:0008038 17 16 0,000 0,01617324 0,0270134 ! oogenesis GO:0048477 19 16 0,000 0,01617324 0,02700077 ! low-density lipoprotein binding GO:0030169 17 16 0,000 0,01617324 0,02698816 ! clathrin vesicle coat GO:0030125 19 16 0,000 0,01617324 0,02697555 ! COPI-coated vesicle GO:0030137 16 16 0,000 0,01617324 0,02696296 ! sphingolipid biosynthetic process GO:0030148 16 16 0,000 0,01617324 0,02695038 ! biomineral formation GO:0031214 16 16 0,000 0,01617324 0,02693781 ! vitamin transport GO:0051180 16 16 0,000 0,01617324 0,02692525 ! folic acid and derivative metabolic process GO:0006760 16 16 0,000 0,01617324 0,0269127 ! organic cation transport GO:0015695 16 16 0,000 0,01617324 0,02690017 ! proximal/distal pattern formation GO:0009954 16 16 0,000 0,01617324 0,02688764 ! regulation of glucose import GO:0046324 17 16 0,000 0,01617324 0,02687513 GO:0010827|regulation of glucose transport, ! aromatic compound biosynthetic process GO:0019438 17 16 0,000 0,01617324 0,02686263 ! aromatic compound catabolic process GO:0019439 18 16 0,000 0,01617324 0,02685014 ! negative regulation of coagulation GO:0050819 18 16 0,000 0,01617324 0,02683766 ! tRNA binding GO:0000049 16 16 0,000 0,01617324 0,0268252 ! regulation of cell killing GO:0031341 20 16 0,000 0,01617324 0,02681275 ! negative regulation of defense response GO:0031348 16 16 0,000 0,01617324 0,0268003 ! regulation of neuronal synaptic plasticity GO:0048168 16 16 0,000 0,01617324 0,02678787 ! hindlimb morphogenesis GO:0035137 16 16 0,000 0,01617324 0,02677545 ! bile acid metabolic process GO:0008206 16 16 0,000 0,01617324 0,02676305 ! axis specification GO:0009798 16 16 0,000 0,01617324 0,02675065 ! adult walking behavior GO:0007628 17 16 0,000 0,01617324 0,02673827 ! C-C chemokine binding GO:0019957 16 16 0,000 0,01617324 0,02672589 GO:0016493|C-C chemokine receptor activity, ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 18 16 0,000 0,01617324 0,02671353 ! protein phosphatase binding GO:0019903 17 16 0,000 0,01617324 0,02670118 ! epidermis morphogenesis GO:0048730 16 16 0,000 0,01617324 0,02668884 ! acyl-CoA dehydrogenase activity GO:0003995 16 16 0,000 0,01617324 0,02667651 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01617324 0,0266642 ! SH2 domain binding GO:0042169 19 16 0,000 0,01617324 0,02665189 ! UDP-galactosyltransferase activity GO:0035250 17 16 0,000 0,01617324 0,0266396 ! RNA methyltransferase activity GO:0008173 16 16 0,000 0,01617324 0,02662732 ! neutral amino acid transport GO:0015804 16 16 0,000 0,01617324 0,02661505 ! glucuronosyltransferase activity GO:0015020 17 16 0,000 0,01617324 0,02660279 ! regulation of alpha-beta T cell differentiation GO:0046637 16 16 0,000 0,01617324 0,02659054 ! cellular pigmentation GO:0033059 16 16 0,000 0,01617324 0,0265783 ! mannosidase activity GO:0015923 19 16 0,000 0,01617324 0,02656608 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 16 16 0,000 0,01617324 0,02655386 ! negative regulation of tissue remodeling GO:0034104 16 16 0,000 0,01617324 0,02654166 ! positive regulation of neurological system process GO:0031646 16 16 0,000 0,01617324 0,02652947 ! neuromuscular synaptic transmission GO:0007274 16 16 0,000 0,01617324 0,02651729 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01617324 0,02650512 ! sperm-egg recognition GO:0035036 17 16 0,000 0,01617324 0,02649296 ! axoneme GO:0005930 16 16 0,000 0,01617324 0,02648081 ! anion exchanger activity GO:0015380 18 17 0,000 0,01717592 0,02810963 ! neuron maturation GO:0042551 18 17 0,000 0,01717592 0,02809675 ! metencephalon development GO:0022037 18 17 0,000 0,01717592 0,02808389 ! reciprocal meiotic recombination GO:0007131 17 17 0,000 0,01717592 0,02807104 ! hemoglobin complex GO:0005833 18 17 0,000 0,01717592 0,0280582 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 17 17 0,000 0,01717592 0,02804537 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 17 17 0,000 0,01717592 0,02803255 ! protein amino acid deacetylation GO:0006476 17 17 0,000 0,01717592 0,02801974 ! protein amino acid acetylation GO:0006473 19 17 0,000 0,01717592 0,02800695 ! positive regulation of nucleocytoplasmic transport GO:0046824 18 17 0,000 0,01717592 0,02799416 ! regulation of neurotransmitter secretion GO:0046928 18 17 0,000 0,01717592 0,02798139 ! striated muscle thick filament GO:0005863 19 17 0,000 0,01717592 0,02796863 GO:0032982|myosin filament, ! glial cell development GO:0021782 17 17 0,000 0,01717592 0,02795589 ! regulation of muscle cell differentiation GO:0051147 17 17 0,000 0,01717592 0,02794315 ! pancreas development GO:0031016 17 17 0,000 0,01717592 0,02793043 ! acetylcholine receptor activity GO:0015464 17 17 0,000 0,01717592 0,02791771 ! nuclear heterochromatin GO:0005720 18 17 0,000 0,01717592 0,02790501 ! calcium-dependent protein binding GO:0048306 19 17 0,000 0,01717592 0,02789232 ! cerebral cortex development GO:0021987 17 17 0,000 0,01717592 0,02787964 ! cellular response to starvation GO:0009267 18 17 0,000 0,01717592 0,02786698 ! signal sequence binding GO:0005048 17 17 0,000 0,01717592 0,02785432 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 17 17 0,000 0,01717592 0,02784168 ! cellular macromolecular complex disassembly GO:0034623 18 17 0,000 0,01717592 0,02782904 ! transforming growth factor beta receptor activity GO:0005024 17 17 0,000 0,01717592 0,02781642 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01717592 0,02780381 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 17 17 0,000 0,01717592 0,02779122 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 17 0,000 0,01717592 0,02777863 ! actin filament bundle GO:0032432 17 17 0,000 0,01717592 0,02776605 GO:0001725|stress fiber, ! small nucleolar ribonucleoprotein complex GO:0005732 17 17 0,000 0,01717592 0,02775349 ! response to lipopolysaccharide GO:0032496 17 17 0,000 0,01717592 0,02774094 ! plasma membrane fusion GO:0045026 18 17 0,000 0,01717592 0,0277284 ! regulation of protein binding GO:0043393 18 17 0,000 0,01717592 0,02771587 ! recycling endosome GO:0055037 18 17 0,000 0,01717592 0,02770335 ! prostaglandin metabolic process GO:0006693 18 17 0,000 0,01717592 0,02769084 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 19 17 0,000 0,01717592 0,02767835 ! regulation of Rho GTPase activity GO:0032319 17 17 0,000 0,01717592 0,02766586 ! regulation of immunoglobulin mediated immune response GO:0002889 21 17 0,000 0,01717592 0,02765339 GO:0002712|regulation of B cell mediated immunity, ! receptor signaling complex scaffold activity GO:0030159 17 17 0,000 0,01717592 0,02764093 ! positive regulation of cytokine secretion GO:0050715 17 17 0,000 0,01717592 0,02762848 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 17 0,000 0,01717592 0,02761604 ! endodeoxyribonuclease activity GO:0004520 17 17 0,000 0,01717592 0,02760361 ! sphingolipid catabolic process GO:0030149 18 17 0,000 0,01717592 0,02759119 ! steroid catabolic process GO:0006706 17 17 0,000 0,01717592 0,02757878 ! oxygen transport GO:0015671 18 17 0,000 0,01717592 0,02756639 GO:0005344|oxygen transporter activity, ! phosphatidylinositol binding GO:0005545 19 17 0,000 0,01717592 0,027554 ! hyaluronic acid binding GO:0005540 17 17 0,000 0,01717592 0,02754163 ! negative regulation of T cell activation GO:0050868 17 17 0,000 0,01717592 0,02752927 ! regulation of glucose metabolic process GO:0010906 17 17 0,000 0,01717592 0,02751692 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 17 17 0,000 0,01717592 0,02750458 ! glycosaminoglycan biosynthetic process GO:0006024 17 17 0,000 0,01717592 0,02749225 ! MAP kinase kinase kinase activity GO:0004709 18 17 0,000 0,01717592 0,02747993 ! L-ascorbic acid binding GO:0031418 17 17 0,000 0,01717592 0,02746763 ! negative regulation of endothelial cell proliferation GO:0001937 17 17 0,000 0,01717592 0,02745533 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 18 17 0,000 0,01717592 0,02744305 ! photoreceptor cell maintenance GO:0045494 17 17 0,000 0,01717592 0,02743078 ! response to carbohydrate stimulus GO:0009743 17 17 0,000 0,01717592 0,02741851 ! calmodulin-dependent protein kinase activity GO:0004683 19 17 0,000 0,01717592 0,02740626 ! fucose metabolic process GO:0006004 19 17 0,000 0,01717592 0,02739402 ! D-ribose metabolic process GO:0006014 18 17 0,000 0,01717592 0,02738179 ! AMP binding GO:0016208 17 17 0,000 0,01717592 0,02736957 ! body fluid secretion GO:0007589 18 17 0,000 0,01717592 0,02735737 ! response to fungus GO:0009620 17 17 0,000 0,01717592 0,02734517 ! positive regulation of alpha-beta T cell activation GO:0046635 21 17 0,000 0,01717592 0,02733298 ! intermediate filament-based process GO:0045103 18 17 0,000 0,01717592 0,02732081 ! rRNA binding GO:0019843 17 17 0,000 0,01717592 0,02730864 ! nucleotide-excision repair, DNA gap filling GO:0006297 18 17 0,000 0,01717592 0,02729649 ! regulation of interleukin-2 production GO:0032663 17 17 0,000 0,01717592 0,02728435 ! voltage-gated chloride channel activity GO:0005247 17 17 0,000 0,01717592 0,02727222 ! DNA fragmentation involved in apoptosis GO:0006309 17 17 0,000 0,01717592 0,0272601 ! neutrophil chemotaxis GO:0030593 18 17 0,000 0,01717592 0,02724799 ! long-chain fatty acid transport GO:0015909 17 17 0,000 0,01717592 0,02723589 ! tissue regeneration GO:0042246 17 17 0,000 0,01717592 0,0272238 ! detection of biotic stimulus GO:0009595 18 17 0,000 0,01717592 0,02721172 ! muscle maintenance GO:0046716 18 17 0,000 0,01717592 0,02719965 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 17 17 0,000 0,01717592 0,0271876 ! somatic recombination of immunoglobulin gene segments GO:0016447 17 17 0,000 0,01717592 0,02717555 ! cell-cell adherens junction GO:0005913 17 17 0,000 0,01717592 0,02716351 ! triacylglycerol lipase activity GO:0004806 17 17 0,000 0,01717592 0,02715149 ! ATP-dependent DNA helicase activity GO:0004003 17 17 0,000 0,01717592 0,02713948 ! positive regulation of ossification GO:0045778 19 18 0,000 0,01817764 0,02870958 ! pteridine and derivative metabolic process GO:0042558 19 18 0,000 0,01817764 0,02869689 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,01817764 0,02868421 GO:0005763|mitochondrial small ribosomal subunit, ! signal complex assembly GO:0007172 18 18 0,000 0,01817764 0,02867154 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 19 18 0,000 0,01817764 0,02865888 ! limbic system development GO:0021761 18 18 0,000 0,01817764 0,02864623 ! cellular response to hydrogen peroxide GO:0070301 18 18 0,000 0,01817764 0,0286336 GO:0042744|hydrogen peroxide catabolic process, ! MHC class II protein complex GO:0042613 18 18 0,000 0,01817764 0,02862097 ! positive regulation of proteolysis GO:0045862 19 18 0,000 0,01817764 0,02860836 ! deoxyribonucleotide metabolic process GO:0009262 19 18 0,000 0,01817764 0,02859576 ! lysosome organization GO:0007040 18 18 0,000 0,01817764 0,02858317 ! central nervous system neuron development GO:0021954 19 18 0,000 0,01817764 0,02857058 ! fatty acid beta-oxidation GO:0006635 18 18 0,000 0,01817764 0,02855802 ! regulation of viral reproduction GO:0050792 18 18 0,000 0,01817764 0,02854546 ! peptide cross-linking GO:0018149 20 18 0,000 0,01817764 0,02853291 ! ventricular cardiac muscle morphogenesis GO:0055010 19 18 0,000 0,01817764 0,02852037 ! presynaptic membrane GO:0042734 19 18 0,000 0,01817764 0,02850785 ! embryonic digit morphogenesis GO:0042733 20 18 0,000 0,01817764 0,02849533 ! neural crest cell migration GO:0001755 18 18 0,000 0,01817764 0,02848283 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,01817764 0,02847034 ! positive regulation of adaptive immune response GO:0002821 22 18 0,000 0,01817764 0,02845786 ! positive regulation of intracellular transport GO:0032388 19 18 0,000 0,01817764 0,02844538 ! negative regulation of intracellular transport GO:0032387 18 18 0,000 0,01817764 0,02843293 ! peptidyl-serine modification GO:0018209 18 18 0,000 0,01817764 0,02842048 ! cell-cell recognition GO:0009988 19 18 0,000 0,01817764 0,02840804 ! vitamin D receptor binding GO:0042809 19 18 0,000 0,01817764 0,02839561 ! porphyrin biosynthetic process GO:0006779 18 18 0,000 0,01817764 0,0283832 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 18 0,000 0,01817764 0,02837079 ! actin filament-based movement GO:0030048 18 18 0,000 0,01817764 0,0283584 ! negative regulation of translation GO:0017148 20 18 0,000 0,01817764 0,02834601 ! Rab GTPase binding GO:0017137 18 18 0,000 0,01817764 0,02833364 ! histone deacetylase activity GO:0004407 19 18 0,000 0,01817764 0,02832128 GO:0033558|protein deacetylase activity, ! protein import into nucleus, docking GO:0000059 18 18 0,000 0,01817764 0,02830893 ! glycerol metabolic process GO:0006071 19 18 0,000 0,01817764 0,02829659 ! post-Golgi vesicle-mediated transport GO:0006892 18 18 0,000 0,01817764 0,02828426 ! intra-Golgi vesicle-mediated transport GO:0006891 18 18 0,000 0,01817764 0,02827194 ! aminoglycan catabolic process GO:0006026 18 18 0,000 0,01817764 0,02825963 ! aminoglycan biosynthetic process GO:0006023 18 18 0,000 0,01817764 0,02824733 ! memory GO:0007613 19 18 0,000 0,01817764 0,02823504 ! C21-steroid hormone metabolic process GO:0008207 18 18 0,000 0,01817764 0,02822277 ! regulation of DNA recombination GO:0000018 22 18 0,000 0,01817764 0,0282105 ! protein phosphatase type 2A complex GO:0000159 20 18 0,000 0,01817764 0,02819825 ! inactivation of MAPK activity GO:0000188 19 18 0,000 0,01817764 0,028186 ! pigmentation during development GO:0048066 21 18 0,000 0,01817764 0,02817377 ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 18 0,000 0,01817764 0,02816155 ! acetylcholine binding GO:0042166 19 18 0,000 0,01817764 0,02814934 ! neurotransmitter:sodium symporter activity GO:0005328 18 18 0,000 0,01817764 0,02813713 ! neurotransmitter metabolic process GO:0042133 23 18 0,000 0,01817764 0,02812494 ! neuromuscular junction development GO:0007528 21 18 0,000 0,01817764 0,02811276 ! nonmotile primary cilium GO:0031513 19 18 0,000 0,01817764 0,02810059 ! coreceptor activity GO:0015026 18 18 0,000 0,01817764 0,02808843 ! behavioral interaction between organisms GO:0051705 18 18 0,000 0,01817764 0,02807628 ! carbonate dehydratase activity GO:0004089 19 18 0,000 0,01817764 0,02806415 ! cytolysis GO:0019835 18 18 0,000 0,01817764 0,02805202 ! phosphate binding GO:0042301 19 18 0,000 0,01817764 0,0280399 ! transport vesicle membrane GO:0030658 21 18 0,000 0,01817764 0,02802779 ! specific transcriptional repressor activity GO:0016566 18 18 0,000 0,01817764 0,0280157 ! DNA modification GO:0006304 20 18 0,000 0,01817764 0,02800361 ! bicarbonate transmembrane transporter activity GO:0015106 19 18 0,000 0,01817764 0,02799153 ! detection of chemical stimulus GO:0009593 19 18 0,000 0,01817764 0,02797947 ! ionotropic glutamate receptor activity GO:0004970 20 18 0,000 0,01817764 0,02796741 ! aspartic-type endopeptidase activity GO:0004190 19 18 0,000 0,01817764 0,02795537 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 18 18 0,000 0,01817764 0,02794334 ! 3'-5' exonuclease activity GO:0008408 18 18 0,000 0,01817764 0,02793131 ! RNA polymerase II transcription mediator activity GO:0016455 19 18 0,000 0,01817764 0,0279193 ! water-soluble vitamin biosynthetic process GO:0042364 19 18 0,000 0,01817764 0,0279073 ! connexon complex GO:0005922 18 18 0,000 0,01817764 0,0278953 ! solute:hydrogen antiporter activity GO:0015299 18 18 0,000 0,01817764 0,02788332 ! mRNA export from nucleus GO:0006406 21 19 0,000 0,01917841 0,0294058 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 20 19 0,000 0,01917841 0,02939318 ! regulation of interferon-gamma production GO:0032649 20 19 0,000 0,01917841 0,02938057 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 20 19 0,000 0,01917841 0,02936798 ! anion:anion antiporter activity GO:0015301 20 19 0,000 0,01917841 0,02935539 ! cAMP metabolic process GO:0046058 19 19 0,000 0,01917841 0,02934281 ! spindle microtubule GO:0005876 20 19 0,000 0,01917841 0,02933024 ! ovarian follicle development GO:0001541 19 19 0,000 0,01917841 0,02931769 ! retinoid metabolic process GO:0001523 19 19 0,000 0,01917841 0,02930514 GO:0016101|diterpenoid metabolic process, ! caspase activator activity GO:0008656 19 19 0,000 0,01917841 0,02929261 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 21 19 0,000 0,01917841 0,02928009 ! vacuolar transport GO:0007034 19 19 0,000 0,01917841 0,02926757 ! threonine-type endopeptidase activity GO:0004298 19 19 0,000 0,01917841 0,02925507 GO:0070003|threonine-type peptidase activity, ! myofibril assembly GO:0030239 19 19 0,000 0,01917841 0,02924258 GO:0055002|striated muscle cell development, ! monocarboxylic acid transmembrane transporter activity GO:0008028 20 19 0,000 0,01917841 0,0292301 ! positive regulation of multicellular organism growth GO:0040018 19 19 0,000 0,01917841 0,02921763 ! cell projection membrane GO:0031253 20 19 0,000 0,01917841 0,02920517 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,01917841 0,02919272 ! transcriptional repressor complex GO:0017053 19 19 0,000 0,01917841 0,02918028 ! vitamin A metabolic process GO:0006776 19 19 0,000 0,01917841 0,02916785 ! positive regulation of myeloid cell differentiation GO:0045639 20 19 0,000 0,01917841 0,02915544 ! negative regulation of myeloid cell differentiation GO:0045638 19 19 0,000 0,01917841 0,02914303 ! glutamine family amino acid catabolic process GO:0009065 21 19 0,000 0,01917841 0,02913063 ! leukotriene biosynthetic process GO:0019370 19 19 0,000 0,01917841 0,02911825 GO:0043450|alkene biosynthetic process, ! gas transport GO:0015669 20 19 0,000 0,01917841 0,02910587 ! retinoid binding GO:0005501 19 19 0,000 0,01917841 0,02909351 GO:0019840|isoprenoid binding, ! peptide hormone secretion GO:0030072 20 19 0,000 0,01917841 0,02908115 ! protein stabilization GO:0050821 20 19 0,000 0,01917841 0,02906881 ! cellular monovalent inorganic cation homeostasis GO:0030004 20 19 0,000 0,01917841 0,02905648 ! myeloid leukocyte differentiation GO:0002573 21 19 0,000 0,01917841 0,02904416 ! protein complex scaffold GO:0032947 19 19 0,000 0,01917841 0,02903184 ! SNAP receptor activity GO:0005484 21 19 0,000 0,01917841 0,02901954 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,01917841 0,02900725 GO:0006479|protein amino acid methylation, ! regulation of systemic arterial blood pressure by hormone GO:0001990 19 19 0,000 0,01917841 0,02899497 GO:0050886|endocrine process, ! visual behavior GO:0007632 22 19 0,000 0,01917841 0,0289827 GO:0008542|visual learning, ! 4 iron, 4 sulfur cluster binding GO:0051539 21 19 0,000 0,01917841 0,02897044 ! glycoprotein binding GO:0001948 23 19 0,000 0,01917841 0,02895819 ! sensory perception of taste GO:0050909 19 19 0,000 0,01917841 0,02894595 ! myoblast differentiation GO:0045445 19 19 0,000 0,01917841 0,02893372 ! cell differentiation in spinal cord GO:0021515 19 19 0,000 0,01917841 0,0289215 ! immune response-activating cell surface receptor signaling pathway GO:0002429 25 19 0,000 0,01917841 0,02890929 ! myosin binding GO:0017022 19 19 0,000 0,01917841 0,0288971 ! organic acid:sodium symporter activity GO:0005343 19 19 0,000 0,01917841 0,02888491 ! cell aging GO:0007569 19 19 0,000 0,01917841 0,02887273 ! stem cell differentiation GO:0048863 19 19 0,000 0,01917841 0,02886056 ! regulation of myeloid leukocyte differentiation GO:0002761 21 19 0,000 0,01917841 0,02884841 ! heart process GO:0003015 20 19 0,000 0,01917841 0,02883626 GO:0060047|heart contraction, ! mismatch repair GO:0006298 19 19 0,000 0,01917841 0,02882412 ! secretory granule membrane GO:0030667 20 19 0,000 0,01917841 0,028812 ! extracellular-glutamate-gated ion channel activity GO:0005234 21 19 0,000 0,01917841 0,02879988 ! chloride transmembrane transporter activity GO:0015108 20 19 0,000 0,01917841 0,02878778 ! GABA-A receptor activity GO:0004890 20 19 0,000 0,01917841 0,02877568 ! response to cytokine stimulus GO:0034097 20 19 0,000 0,01917841 0,02876359 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,01917841 0,02875152 ! translation elongation factor activity GO:0003746 22 19 0,000 0,01917841 0,02873945 ! insulin receptor binding GO:0005158 20 19 0,000 0,01917841 0,0287274 ! phosphoprotein phosphatase inhibitor activity GO:0004864 21 19 0,000 0,01917841 0,02871535 ! protein secretion GO:0009306 20 20 0,000 0,02017823 0,03019969 ! positive regulation of angiogenesis GO:0045766 22 20 0,000 0,02017823 0,03018704 ! proteasome core complex GO:0005839 20 20 0,000 0,02017823 0,0301744 ! positive regulation of bone remodeling GO:0046852 21 20 0,000 0,02017823 0,03016177 ! heterophilic cell adhesion GO:0007157 21 20 0,000 0,02017823 0,03014915 ! glutathione transferase activity GO:0004364 20 20 0,000 0,02017823 0,03013654 ! positive regulation of endocytosis GO:0045807 20 20 0,000 0,02017823 0,03012394 ! actomyosin GO:0042641 20 20 0,000 0,02017823 0,03011135 ! positive regulation of innate immune response GO:0045089 20 20 0,000 0,02017823 0,03009878 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 20 0,000 0,02017823 0,03008621 ! vacuole organization GO:0007033 20 20 0,000 0,02017823 0,03007365 ! oxidoreductase activity, acting on heme group of donors GO:0016675 21 20 0,000 0,02017823 0,03006111 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! purine ribonucleoside metabolic process GO:0046128 23 20 0,000 0,02017823 0,03004857 GO:0042278|purine nucleoside metabolic process, ! chromosome condensation GO:0030261 20 20 0,000 0,02017823 0,03003604 ! regulation of exocytosis GO:0017157 21 20 0,000 0,02017823 0,03002353 ! vitamin biosynthetic process GO:0009110 21 20 0,000 0,02017823 0,03001102 ! glycosphingolipid metabolic process GO:0006687 20 20 0,000 0,02017823 0,02999853 ! kinase activator activity GO:0019209 20 20 0,000 0,02017823 0,02998605 ! diencephalon development GO:0021536 20 20 0,000 0,02017823 0,02997357 ! nuclear inner membrane GO:0005637 20 20 0,000 0,02017823 0,02996111 ! positive regulation of locomotion GO:0040017 20 20 0,000 0,02017823 0,02994866 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! synaptic vesicle transport GO:0048489 21 20 0,000 0,02017823 0,02993622 ! proteoglycan biosynthetic process GO:0030166 20 20 0,000 0,02017823 0,02992378 ! leukocyte homeostasis GO:0001776 22 20 0,000 0,02017823 0,02991136 ! regulation of blood coagulation GO:0030193 22 20 0,000 0,02017823 0,02989895 ! positive regulation of osteoblast differentiation GO:0045669 22 20 0,000 0,02017823 0,02988655 ! regulation of generation of precursor metabolites and energy GO:0043467 21 20 0,000 0,02017823 0,02987416 ! ligase activity, forming carbon-sulfur bonds GO:0016877 20 20 0,000 0,02017823 0,02986178 ! phosphorus-oxygen lyase activity GO:0016849 20 20 0,000 0,02017823 0,02984941 ! embryonic organ morphogenesis GO:0048562 22 20 0,000 0,02017823 0,02983705 ! liver development GO:0001889 20 20 0,000 0,02017823 0,0298247 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 20 0,000 0,02017823 0,02981236 ! chromosome, telomeric region GO:0000781 21 20 0,000 0,02017823 0,02980003 ! calcium-independent cell-cell adhesion GO:0016338 20 20 0,000 0,02017823 0,02978771 ! response to alkaloid GO:0043279 22 20 0,000 0,02017823 0,0297754 ! regulation of cell-matrix adhesion GO:0001952 22 20 0,000 0,02017823 0,0297631 GO:0010810|regulation of cell-substrate adhesion, ! transmembrane receptor protein phosphatase activity GO:0019198 27 20 0,000 0,02017823 0,02975081 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! smooth muscle contraction GO:0006939 21 20 0,000 0,02017823 0,02973853 ! heme metabolic process GO:0042168 22 20 0,000 0,02017823 0,02972627 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 20 20 0,000 0,02017823 0,02971401 ! sex determination GO:0007530 20 20 0,000 0,02017823 0,02970176 ! negative regulation of protein catabolic process GO:0042177 21 20 0,000 0,02017823 0,02968952 ! peptide secretion GO:0002790 21 20 0,000 0,02017823 0,02967729 ! regulation of alpha-beta T cell activation GO:0046634 24 20 0,000 0,02017823 0,02966508 ! interaction with host GO:0051701 24 20 0,000 0,02017823 0,02965287 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 26 20 0,000 0,02017823 0,02964067 ! vasodilation GO:0042311 21 20 0,000 0,02017823 0,02962848 ! regulation of tumor necrosis factor production GO:0032680 20 20 0,000 0,02017823 0,0296163 ! regulation of chromosome organization GO:0033044 20 20 0,000 0,02017823 0,02960414 ! inward rectifier potassium channel activity GO:0005242 20 20 0,000 0,02017823 0,02959198 ! activation of JUN kinase activity GO:0007257 20 20 0,000 0,02017823 0,02957983 ! cyclic nucleotide binding GO:0030551 22 20 0,000 0,02017823 0,02956769 ! somatic diversification of immunoglobulins GO:0016445 20 20 0,000 0,02017823 0,02955557 ! microvillus GO:0005902 20 20 0,000 0,02017823 0,02954345 ! tumor necrosis factor receptor binding GO:0005164 20 20 0,000 0,02017823 0,02953134 ! ATP-dependent RNA helicase activity GO:0004004 20 20 0,000 0,02017823 0,02951924 ! positive regulation of protein catabolic process GO:0045732 22 21 0,000 0,0211771 0,03096782 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 22 21 0,000 0,0211771 0,03095515 ! growth cone GO:0030426 22 21 0,000 0,0211771 0,03094248 ! oligosaccharide metabolic process GO:0009311 23 21 0,000 0,0211771 0,03092983 ! regulation of anti-apoptosis GO:0045767 21 21 0,000 0,0211771 0,03091718 ! hormone secretion GO:0046879 22 21 0,000 0,0211771 0,03090455 ! protein amino acid O-linked glycosylation GO:0006493 22 21 0,000 0,0211771 0,03089192 ! transition metal ion transmembrane transporter activity GO:0046915 21 21 0,000 0,0211771 0,03087931 ! voltage-gated calcium channel complex GO:0005891 24 21 0,000 0,0211771 0,0308667 GO:0034704|calcium channel complex, ! dicarboxylic acid metabolic process GO:0043648 22 21 0,000 0,0211771 0,03085411 ! apoptotic mitochondrial changes GO:0008637 21 21 0,000 0,0211771 0,03084153 ! protein phosphatase type 2A regulator activity GO:0008601 23 21 0,000 0,0211771 0,03082895 ! histone-lysine N-methyltransferase activity GO:0018024 23 21 0,000 0,0211771 0,03081639 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! activation of pro-apoptotic gene products GO:0008633 22 21 0,000 0,0211771 0,03080384 ! mitochondrial membrane organization GO:0007006 22 21 0,000 0,0211771 0,0307913 ! central nervous system neuron differentiation GO:0021953 22 21 0,000 0,0211771 0,03077876 ! Golgi stack GO:0005795 25 21 0,000 0,0211771 0,03076624 ! regulation of endothelial cell migration GO:0010594 21 21 0,000 0,0211771 0,03075373 ! muscle cell development GO:0055001 21 21 0,000 0,0211771 0,03074123 ! cholesterol biosynthetic process GO:0006695 22 21 0,000 0,0211771 0,03072874 ! regulation of vasoconstriction GO:0019229 22 21 0,000 0,0211771 0,03071626 ! deacetylase activity GO:0019213 22 21 0,000 0,0211771 0,03070379 ! phosphatase inhibitor activity GO:0019212 23 21 0,000 0,0211771 0,03069132 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,0211771 0,03067887 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! sensory perception of pain GO:0019233 21 21 0,000 0,0211771 0,03066643 ! pentose metabolic process GO:0019321 22 21 0,000 0,0211771 0,030654 ! collagen fibril organization GO:0030199 22 21 0,000 0,0211771 0,03064158 ! platelet activation GO:0030168 23 21 0,000 0,0211771 0,03062917 ! response to glucocorticoid stimulus GO:0051384 22 21 0,000 0,0211771 0,03061677 ! trans-Golgi network transport vesicle GO:0030140 24 21 0,000 0,0211771 0,03060438 ! glutathione metabolic process GO:0006749 21 21 0,000 0,0211771 0,030592 ! DNA-directed RNA polymerase complex GO:0000428 22 21 0,000 0,0211771 0,03057963 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! terpenoid metabolic process GO:0006721 21 21 0,000 0,0211771 0,03056727 ! cyclase activity GO:0009975 21 21 0,000 0,0211771 0,03055492 ! intramolecular transferase activity GO:0016866 22 21 0,000 0,0211771 0,03054258 ! negative regulation of cytokine production GO:0001818 21 21 0,000 0,0211771 0,03053025 ! fatty acid binding GO:0005504 21 21 0,000 0,0211771 0,03051793 ! gut development GO:0048565 21 21 0,000 0,0211771 0,03050562 ! acetyl-CoA catabolic process GO:0046356 21 21 0,000 0,0211771 0,03049332 GO:0006099|tricarboxylic acid cycle, ! phosphoinositide phospholipase C activity GO:0004435 21 21 0,000 0,0211771 0,03048103 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! protein tetramerization GO:0051262 22 21 0,000 0,0211771 0,03046874 ! regulation of microtubule polymerization or depolymerization GO:0031110 23 21 0,000 0,0211771 0,03045647 ! sulfur amino acid metabolic process GO:0000096 22 21 0,000 0,0211771 0,03044421 ! voltage-gated anion channel activity GO:0008308 21 21 0,000 0,0211771 0,03043196 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,0211771 0,03041972 ! cellular polysaccharide biosynthetic process GO:0033692 21 21 0,000 0,0211771 0,03040749 ! positive regulation of JAK-STAT cascade GO:0046427 22 21 0,000 0,0211771 0,03039527 ! sterol binding GO:0032934 21 21 0,000 0,0211771 0,03038305 ! regulation of chemotaxis GO:0050920 21 21 0,000 0,0211771 0,03037085 ! regulation of carbohydrate metabolic process GO:0006109 22 21 0,000 0,0211771 0,03035866 GO:0010675|regulation of cellular carbohydrate metabolic process, ! superoxide metabolic process GO:0006801 21 21 0,000 0,0211771 0,03034648 ! calcium-dependent cell-cell adhesion GO:0016339 21 21 0,000 0,0211771 0,03033431 ! phosphatase binding GO:0019902 22 21 0,000 0,0211771 0,03032214 ! NAD+ ADP-ribosyltransferase activity GO:0003950 21 21 0,000 0,0211771 0,03030999 ! positive regulation of cytoskeleton organization GO:0051495 21 21 0,000 0,0211771 0,03029785 ! negative regulation of DNA replication GO:0008156 25 21 0,000 0,0211771 0,03028571 ! vesicle targeting GO:0006903 22 21 0,000 0,0211771 0,03027359 ! vesicle docking during exocytosis GO:0006904 21 21 0,000 0,0211771 0,03026147 ! cell structure disassembly during apoptosis GO:0006921 21 21 0,000 0,0211771 0,03024937 ! RNA-dependent ATPase activity GO:0008186 21 21 0,000 0,0211771 0,03023727 ! renal system process GO:0003014 22 21 0,000 0,0211771 0,03022519 ! base-excision repair GO:0006284 21 21 0,000 0,0211771 0,03021311 ! positive regulation of leukocyte mediated immunity GO:0002705 25 21 0,000 0,0211771 0,03020105 GO:0002708|positive regulation of lymphocyte mediated immunity, ! nuclear-transcribed mRNA catabolic process GO:0000956 22 21 0,000 0,0211771 0,03018899 ! apoptotic protease activator activity GO:0016505 21 21 0,000 0,0211771 0,03017694 ! fatty acid transport GO:0015908 21 21 0,000 0,0211771 0,03016491 ! sarcoplasmic reticulum GO:0016529 22 21 0,000 0,0211771 0,03015288 ! positive regulation of tissue remodeling GO:0034105 22 21 0,000 0,0211771 0,03014086 ! collagen catabolic process GO:0030574 21 21 0,000 0,0211771 0,03012885 ! pyrimidine nucleotide biosynthetic process GO:0006221 25 21 0,000 0,0211771 0,03011686 ! regulation of multi-organism process GO:0043900 21 21 0,000 0,0211771 0,03010487 ! ubiquitin-specific protease activity GO:0004843 22 21 0,000 0,0211771 0,03009289 ! positive regulation of DNA replication GO:0045740 23 22 0,000 0,02217502 0,0314984 ! positive regulation of cell adhesion GO:0045785 23 22 0,000 0,02217502 0,03148588 ! leukocyte adhesion GO:0007159 27 22 0,000 0,02217502 0,03147336 ! glutamate signaling pathway GO:0007215 25 22 0,000 0,02217502 0,03146086 ! potassium channel regulator activity GO:0015459 24 22 0,000 0,02217502 0,03144836 ! peroxisome organization GO:0007031 22 22 0,000 0,02217502 0,03143588 ! cellular response to reactive oxygen species GO:0034614 22 22 0,000 0,02217502 0,03142341 ! polysaccharide catabolic process GO:0000272 22 22 0,000 0,02217502 0,03141094 ! response to starvation GO:0042594 23 22 0,000 0,02217502 0,03139849 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 22 22 0,000 0,02217502 0,03138604 ! coenzyme catabolic process GO:0009109 22 22 0,000 0,02217502 0,03137361 ! regulation of insulin secretion GO:0050796 23 22 0,000 0,02217502 0,03136118 ! membrane depolarization GO:0051899 24 22 0,000 0,02217502 0,03134877 ! somitogenesis GO:0001756 23 22 0,000 0,02217502 0,03133636 ! regulation of cytokine secretion GO:0050707 22 22 0,000 0,02217502 0,03132396 ! natural killer cell activation GO:0030101 22 22 0,000 0,02217502 0,03131158 ! aromatic amino acid family metabolic process GO:0009072 25 22 0,000 0,02217502 0,0312992 ! basal plasma membrane GO:0009925 22 22 0,000 0,02217502 0,03128684 GO:0045178|basal part of cell, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 22 22 0,000 0,02217502 0,03127448 ! camera-type eye morphogenesis GO:0048593 25 22 0,000 0,02217502 0,03126213 ! telomere organization GO:0032200 23 22 0,000 0,02217502 0,0312498 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 24 22 0,000 0,02217502 0,03123747 GO:0060606|tube closure, ! response to molecule of bacterial origin GO:0002237 22 22 0,000 0,02217502 0,03122515 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 22 0,000 0,02217502 0,03121284 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 22 22 0,000 0,02217502 0,03120054 GO:0016444|somatic cell DNA recombination, ! cortical actin cytoskeleton GO:0030864 22 22 0,000 0,02217502 0,03118826 ! initiation of viral infection GO:0019059 22 22 0,000 0,02217502 0,03117598 ! RNA polymerase complex GO:0030880 23 22 0,000 0,02217502 0,03116371 ! regulation of neurotransmitter transport GO:0051588 23 22 0,000 0,02217502 0,03115145 ! macromolecular complex disassembly GO:0032984 23 22 0,000 0,02217502 0,0311392 ! response to ethanol GO:0045471 25 22 0,000 0,02217502 0,03112696 ! syntaxin binding GO:0019905 23 22 0,000 0,02217502 0,03111473 ! regulation of nitric oxide biosynthetic process GO:0045428 22 22 0,000 0,02217502 0,03110251 ! digestive system process GO:0022600 24 22 0,000 0,02217502 0,0310903 ! neurotransmitter transporter activity GO:0005326 22 22 0,000 0,02217502 0,03107809 ! autophagy GO:0006914 24 22 0,000 0,02217502 0,0310659 ! carbohydrate kinase activity GO:0019200 22 22 0,000 0,02217502 0,03105372 ! neuropeptide hormone activity GO:0005184 23 22 0,000 0,02217502 0,03104155 ! transaminase activity GO:0008483 23 22 0,000 0,02217502 0,03102938 ! sarcoplasm GO:0016528 23 22 0,000 0,02217502 0,03101723 ! metallocarboxypeptidase activity GO:0004181 23 22 0,000 0,02217502 0,03100508 ! cellular response to nutrient levels GO:0031669 23 22 0,000 0,02217502 0,03099295 ! positive regulation of nuclear division GO:0051785 22 22 0,000 0,02217502 0,03098082 GO:0045840|positive regulation of mitosis, ! nerve-nerve synaptic transmission GO:0007270 25 22 0,000 0,02217502 0,03096871 ! small conjugating protein-specific protease activity GO:0019783 24 22 0,000 0,02217502 0,0309566 ! pyrimidine nucleoside metabolic process GO:0006213 25 22 0,000 0,02217502 0,0309445 ! solute:cation antiporter activity GO:0015298 22 22 0,000 0,02217502 0,03093242 ! translational initiation GO:0006413 23 23 0,000 0,02317198 0,03231048 ! NF-kappaB binding GO:0051059 23 23 0,000 0,02317198 0,03229787 ! vesicle docking GO:0048278 23 23 0,000 0,02317198 0,03228527 ! muscle myosin complex GO:0005859 25 23 0,000 0,02317198 0,03227268 ! vasculogenesis GO:0001570 25 23 0,000 0,02317198 0,0322601 ! regulation of innate immune response GO:0045088 23 23 0,000 0,02317198 0,03224753 ! positive regulation of epithelial cell proliferation GO:0050679 24 23 0,000 0,02317198 0,03223496 ! response to corticosteroid stimulus GO:0031960 24 23 0,000 0,02317198 0,03222241 ! apoptotic nuclear changes GO:0030262 23 23 0,000 0,02317198 0,03220987 ! barbed-end actin filament capping GO:0051016 23 23 0,000 0,02317198 0,03219733 GO:0051693|actin filament capping, ! regulation of behavior GO:0050795 23 23 0,000 0,02317198 0,03218481 ! cardiac muscle tissue morphogenesis GO:0055008 24 23 0,000 0,02317198 0,0321723 GO:0060415|muscle tissue morphogenesis, ! cyclic nucleotide biosynthetic process GO:0009190 23 23 0,000 0,02317198 0,03215979 ! leukotriene metabolic process GO:0006691 23 23 0,000 0,02317198 0,0321473 ! positive regulation of T cell differentiation GO:0045582 27 23 0,000 0,02317198 0,03213482 ! glycolipid metabolic process GO:0006664 23 23 0,000 0,02317198 0,03212234 ! regulation of ARF GTPase activity GO:0032312 26 23 0,000 0,02317198 0,03210988 ! pallium development GO:0021543 23 23 0,000 0,02317198 0,03209742 ! positive regulation of MAPKKK cascade GO:0043410 30 23 0,000 0,02317198 0,03208498 ! regulation of response to biotic stimulus GO:0002831 23 23 0,000 0,02317198 0,03207254 ! MHC class II receptor activity GO:0032395 23 23 0,000 0,02317198 0,03206011 ! nicotinamide metabolic process GO:0006769 23 23 0,000 0,02317198 0,0320477 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of neuron differentiation GO:0045665 23 23 0,000 0,02317198 0,03203529 ! aspartate family amino acid metabolic process GO:0009066 24 23 0,000 0,02317198 0,03202289 ! cell surface binding GO:0043498 25 23 0,000 0,02317198 0,0320105 ! collagen binding GO:0005518 27 23 0,000 0,02317198 0,03199812 ! insulin-like growth factor binding GO:0005520 23 23 0,000 0,02317198 0,03198576 ! regulation of amine transport GO:0051952 23 23 0,000 0,02317198 0,0319734 ! tissue homeostasis GO:0001894 24 23 0,000 0,02317198 0,03196105 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 25 23 0,000 0,02317198 0,03194871 ! protein import into nucleus, translocation GO:0000060 25 23 0,000 0,02317198 0,03193638 ! gluconeogenesis GO:0006094 24 23 0,000 0,02317198 0,03192406 ! iron ion transport GO:0006826 24 23 0,000 0,02317198 0,03191174 ! nucleotide-excision repair, DNA damage removal GO:0000718 24 23 0,000 0,02317198 0,03189944 ! N-acetylglucosamine metabolic process GO:0006044 23 23 0,000 0,02317198 0,03188715 ! molting cycle process GO:0022404 23 23 0,000 0,02317198 0,03187487 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! circadian rhythm GO:0007623 24 23 0,000 0,02317198 0,03186259 ! tube lumen formation GO:0035148 26 23 0,000 0,02317198 0,03185033 ! insulin receptor signaling pathway GO:0008286 28 23 0,000 0,02317198 0,03183807 ! multicellular organismal response to stress GO:0033555 23 23 0,000 0,02317198 0,03182583 ! immune response-activating signal transduction GO:0002757 29 23 0,000 0,02317198 0,03181359 ! lymphocyte proliferation GO:0046651 29 23 0,000 0,02317198 0,03180136 ! fibroblast growth factor receptor signaling pathway GO:0008543 24 23 0,000 0,02317198 0,03178915 ! regulation of bone mineralization GO:0030500 25 23 0,000 0,02317198 0,03177694 ! single-stranded RNA binding GO:0003727 24 23 0,000 0,02317198 0,03176474 ! brush border GO:0005903 25 23 0,000 0,02317198 0,03175255 ! gap junction GO:0005921 23 23 0,000 0,02317198 0,03174037 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 25 24 0,000 0,024168 0,033092 ! regulation of transmembrane transport GO:0034762 24 24 0,000 0,024168 0,03307931 ! heterotrimeric G-protein complex GO:0005834 24 24 0,000 0,024168 0,03306664 ! protein amino acid acylation GO:0043543 26 24 0,000 0,024168 0,03305398 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 24 0,000 0,024168 0,03304132 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 25 24 0,000 0,024168 0,03302868 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,024168 0,03301604 ! MHC class I protein complex GO:0042612 24 24 0,000 0,024168 0,03300342 ! G-protein chemoattractant receptor activity GO:0001637 24 24 0,000 0,024168 0,0329908 GO:0004950|chemokine receptor activity, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 24 24 0,000 0,024168 0,03297819 ! early endosome membrane GO:0031901 26 24 0,000 0,024168 0,0329656 ! primary neural tube formation GO:0014020 26 24 0,000 0,024168 0,03295301 ! ARF GTPase activator activity GO:0008060 27 24 0,000 0,024168 0,03294043 ! hydrogen peroxide metabolic process GO:0042743 24 24 0,000 0,024168 0,03292786 ! immunoglobulin production GO:0002377 28 24 0,000 0,024168 0,03291531 GO:0002440|production of molecular mediator of immune response, ! lipid kinase activity GO:0001727 26 24 0,000 0,024168 0,03290276 ! positive regulation of protein secretion GO:0050714 26 24 0,000 0,024168 0,03289022 ! MHC class I receptor activity GO:0032393 24 24 0,000 0,024168 0,03287769 ! RNA splicing factor activity, transesterification mechanism GO:0031202 24 24 0,000 0,024168 0,03286517 ! fat-soluble vitamin metabolic process GO:0006775 24 24 0,000 0,024168 0,03285266 ! regulation of osteoblast differentiation GO:0045667 27 24 0,000 0,024168 0,03284016 ! cellular alkene metabolic process GO:0043449 24 24 0,000 0,024168 0,03282766 ! somatic diversification of immune receptors GO:0002200 24 24 0,000 0,024168 0,03281518 ! calcium-dependent phospholipid binding GO:0005544 24 24 0,000 0,024168 0,03280271 ! positive regulation of JUN kinase activity GO:0043507 24 24 0,000 0,024168 0,03279025 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 26 24 0,000 0,024168 0,03277779 ! Z disc GO:0030018 27 24 0,000 0,024168 0,03276535 ! negative regulation of lymphocyte activation GO:0051250 24 24 0,000 0,024168 0,03275291 ! alkaloid metabolic process GO:0009820 24 24 0,000 0,024168 0,03274049 ! neuron fate commitment GO:0048663 24 24 0,000 0,024168 0,03272807 ! DNA catabolic process, endonucleolytic GO:0000737 24 24 0,000 0,024168 0,03271567 ! glucosamine metabolic process GO:0006041 24 24 0,000 0,024168 0,03270327 ! regulation of transcription factor import into nucleus GO:0042990 25 24 0,000 0,024168 0,03269088 ! glucose transport GO:0015758 24 24 0,000 0,024168 0,0326785 ! dendrite development GO:0016358 26 24 0,000 0,024168 0,03266614 ! negative regulation of protein modification process GO:0031400 28 24 0,000 0,024168 0,03265378 ! catechol metabolic process GO:0009712 27 24 0,000 0,024168 0,03264143 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phospholipase A2 activity GO:0004623 26 24 0,000 0,024168 0,03262909 ! immune response-regulating signal transduction GO:0002764 30 24 0,000 0,024168 0,03261675 ! regulation of production of molecular mediator of immune response GO:0002700 28 24 0,000 0,024168 0,03260443 ! DNA-directed DNA polymerase activity GO:0003887 25 24 0,000 0,024168 0,03259212 ! synaptogenesis GO:0007416 25 24 0,000 0,024168 0,03257982 ! selenium binding GO:0008430 24 24 0,000 0,024168 0,03256752 ! leukocyte proliferation GO:0070661 30 24 0,000 0,024168 0,03255524 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 26 24 0,000 0,024168 0,03254296 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 25 25 0,000 0,02516307 0,03387008 ! RNA export from nucleus GO:0006405 27 25 0,000 0,02516307 0,03385732 ! phenol metabolic process GO:0018958 28 25 0,000 0,02516307 0,03384457 ! myelination GO:0042552 26 25 0,000 0,02516307 0,03383182 ! epidermal growth factor receptor signaling pathway GO:0007173 28 25 0,000 0,02516307 0,03381909 ! actin filament GO:0005884 28 25 0,000 0,02516307 0,03380637 ! hexose transport GO:0008645 25 25 0,000 0,02516307 0,03379365 GO:0015749|monosaccharide transport, ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 27 25 0,000 0,02516307 0,03378095 ! PML body GO:0016605 28 25 0,000 0,02516307 0,03376825 ! negative regulation of cell development GO:0010721 28 25 0,000 0,02516307 0,03375557 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 27 25 0,000 0,02516307 0,03374289 ! cell fate determination GO:0001709 25 25 0,000 0,02516307 0,03373023 ! regulation of oxidoreductase activity GO:0051341 25 25 0,000 0,02516307 0,03371757 ! group transfer coenzyme metabolic process GO:0006752 26 25 0,000 0,02516307 0,03370492 ! hormone transport GO:0009914 26 25 0,000 0,02516307 0,03369229 ! neuromuscular process controlling balance GO:0050885 26 25 0,000 0,02516307 0,03367966 ! porphyrin metabolic process GO:0006778 27 25 0,000 0,02516307 0,03366704 GO:0033013|tetrapyrrole metabolic process, ! blastocyst development GO:0001824 25 25 0,000 0,02516307 0,03365443 ! regulation of JUN kinase activity GO:0043506 25 25 0,000 0,02516307 0,03364183 ! cell adhesion molecule binding GO:0050839 27 25 0,000 0,02516307 0,03362924 ! negative regulation of actin filament depolymerization GO:0030835 25 25 0,000 0,02516307 0,03361666 ! acetyl-CoA metabolic process GO:0006084 25 25 0,000 0,02516307 0,03360409 ! membrane lipid catabolic process GO:0046466 26 25 0,000 0,02516307 0,03359152 ! zinc ion transport GO:0006829 26 25 0,000 0,02516307 0,03357897 ! heterochromatin GO:0000792 26 25 0,000 0,02516307 0,03356643 ! cellular iron ion homeostasis GO:0006879 25 25 0,000 0,02516307 0,03355389 ! phototransduction GO:0007602 25 25 0,000 0,02516307 0,03354137 ! keratinization GO:0031424 26 25 0,000 0,02516307 0,03352885 ! spinal cord development GO:0021510 25 25 0,000 0,02516307 0,03351635 ! cyclin-dependent protein kinase activity GO:0004693 26 25 0,000 0,02516307 0,03350385 ! regulation of smooth muscle contraction GO:0006940 28 25 0,000 0,02516307 0,03349136 ! response to toxin GO:0009636 25 25 0,000 0,02516307 0,03347888 ! regulation of peptide secretion GO:0002791 26 25 0,000 0,02516307 0,03346642 ! determination of left/right symmetry GO:0007368 25 25 0,000 0,02516307 0,03345396 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 25 0,000 0,02516307 0,03344151 ! regulation of interleukin-6 production GO:0032675 25 25 0,000 0,02516307 0,03342906 ! voltage-gated calcium channel activity GO:0005245 28 25 0,000 0,02516307 0,03341663 ! phospholipid transport GO:0015914 26 25 0,000 0,02516307 0,03340421 ! peptidase activator activity GO:0016504 25 25 0,000 0,02516307 0,0333918 ! protein localization in mitochondrion GO:0070585 26 25 0,000 0,02516307 0,03337939 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 25 25 0,000 0,02516307 0,033367 ! ethanolamine and derivative metabolic process GO:0042439 28 25 0,000 0,02516307 0,03335461 ! small nuclear ribonucleoprotein complex GO:0030532 25 25 0,000 0,02516307 0,03334224 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 25 25 0,000 0,02516307 0,03332987 ! negative regulation of transcription regulator activity GO:0090048 26 25 0,000 0,02516307 0,03331751 GO:0043433|negative regulation of transcription factor activity, ! acetylgalactosaminyltransferase activity GO:0008376 27 25 0,000 0,02516307 0,03330516 ! solute:solute antiporter activity GO:0015300 26 26 0,000 0,02615719 0,03460813 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 27 26 0,000 0,02615719 0,03459531 ! regeneration GO:0031099 26 26 0,000 0,02615719 0,0345825 ! cholesterol homeostasis GO:0042632 26 26 0,000 0,02615719 0,0345697 GO:0055092|sterol homeostasis, ! peptidyl-tyrosine phosphorylation GO:0018108 27 26 0,000 0,02615719 0,03455691 ! ureteric bud development GO:0001657 26 26 0,000 0,02615719 0,03454413 ! neural crest cell development GO:0014032 26 26 0,000 0,02615719 0,03453136 GO:0014033|neural crest cell differentiation, ! negative regulation of protein kinase cascade GO:0010741 27 26 0,000 0,02615719 0,0345186 ! cellular response to oxidative stress GO:0034599 26 26 0,000 0,02615719 0,03450585 ! lipid oxidation GO:0034440 26 26 0,000 0,02615719 0,03449311 GO:0019395|fatty acid oxidation, ! positive regulation of lymphocyte differentiation GO:0045621 30 26 0,000 0,02615719 0,03448038 ! pyridine nucleotide metabolic process GO:0019362 26 26 0,000 0,02615719 0,03446765 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 26 26 0,000 0,02615719 0,03445494 ! carboxy-lyase activity GO:0016831 26 26 0,000 0,02615719 0,03444223 ! myeloid leukocyte activation GO:0002274 27 26 0,000 0,02615719 0,03442954 ! negative regulation of neuron apoptosis GO:0043524 26 26 0,000 0,02615719 0,03441685 ! negative regulation of catabolic process GO:0009895 28 26 0,000 0,02615719 0,03440418 ! lysine N-acetyltransferase activity GO:0004468 26 26 0,000 0,02615719 0,03439151 GO:0004402|histone acetyltransferase activity, ! regulation of actin filament depolymerization GO:0030834 26 26 0,000 0,02615719 0,03437885 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02615719 0,0343662 ! determination of bilateral symmetry GO:0009855 26 26 0,000 0,02615719 0,03435356 GO:0009799|determination of symmetry, ! regulation of cellular catabolic process GO:0031329 28 26 0,000 0,02615719 0,03434093 ! pyruvate metabolic process GO:0006090 27 26 0,000 0,02615719 0,03432831 ! cellular component assembly involved in morphogenesis GO:0010927 26 26 0,000 0,02615719 0,0343157 ! histone methyltransferase activity GO:0042054 29 26 0,000 0,02615719 0,0343031 ! regulation of endothelial cell proliferation GO:0001936 27 26 0,000 0,02615719 0,03429051 ! chemokine binding GO:0019956 26 26 0,000 0,02615719 0,03427792 ! receptor metabolic process GO:0043112 28 26 0,000 0,02615719 0,03426535 ! histone deacetylase complex GO:0000118 27 26 0,000 0,02615719 0,03425278 ! phospholipase C activity GO:0004629 27 26 0,000 0,02615719 0,03424023 ! negative regulation of leukocyte activation GO:0002695 26 26 0,000 0,02615719 0,03422768 ! receptor regulator activity GO:0030545 26 26 0,000 0,02615719 0,03421514 ! galactosyltransferase activity GO:0008378 27 26 0,000 0,02615719 0,03420261 ! response to heat GO:0009408 26 26 0,000 0,02615719 0,03419009 ! positive regulation of immune effector process GO:0002699 30 26 0,000 0,02615719 0,03417758 ! mRNA catabolic process GO:0006402 28 27 0,000 0,02715037 0,03546232 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 28 27 0,000 0,02715037 0,03544935 ! actomyosin structure organization GO:0031032 28 27 0,000 0,02715037 0,03543639 ! nucleotide receptor activity, G-protein coupled GO:0001608 27 27 0,000 0,02715037 0,03542345 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 28 27 0,000 0,02715037 0,03541051 ! iron ion homeostasis GO:0055072 27 27 0,000 0,02715037 0,03539758 ! lipoprotein binding GO:0008034 29 27 0,000 0,02715037 0,03538466 ! deaminase activity GO:0019239 27 27 0,000 0,02715037 0,03537175 ! mesoderm formation GO:0001707 28 27 0,000 0,02715037 0,03535885 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 27 27 0,000 0,02715037 0,03534596 ! phospholipid transporter activity GO:0005548 29 27 0,000 0,02715037 0,03533308 ! neural tube formation GO:0001841 29 27 0,000 0,02715037 0,03532021 ! mitotic sister chromatid segregation GO:0000070 27 27 0,000 0,02715037 0,03530735 ! regulation of smooth muscle cell proliferation GO:0048660 27 27 0,000 0,02715037 0,03529449 ! integrin complex GO:0008305 28 27 0,000 0,02715037 0,03528165 ! nuclear chromatin GO:0000790 28 27 0,000 0,02715037 0,03526882 ! collagen metabolic process GO:0032963 27 27 0,000 0,02715037 0,03525599 ! post-embryonic development GO:0009791 29 27 0,000 0,02715037 0,03524317 ! antigen processing and presentation of peptide antigen GO:0048002 28 27 0,000 0,02715037 0,03523037 ! ovulation cycle process GO:0022602 27 27 0,000 0,02715037 0,03521757 ! SNARE binding GO:0000149 28 27 0,000 0,02715037 0,03520478 ! biogenic amine biosynthetic process GO:0042401 28 27 0,000 0,02715037 0,035192 ! spindle pole GO:0000922 28 27 0,000 0,02715037 0,03517924 ! anion:cation symporter activity GO:0015296 28 27 0,000 0,02715037 0,03516648 ! trans-Golgi network GO:0005802 29 28 0,000 0,0281426 0,03643844 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 28 0,000 0,0281426 0,03642524 ! cholesterol transport GO:0030301 28 28 0,000 0,0281426 0,03641204 GO:0015918|sterol transport, ! thyroid hormone receptor binding GO:0046966 29 28 0,000 0,0281426 0,03639885 ! dynein complex GO:0030286 29 28 0,000 0,0281426 0,03638567 ! formation of primary germ layer GO:0001704 29 28 0,000 0,0281426 0,0363725 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 30 28 0,000 0,0281426 0,03635935 ! ovulation cycle GO:0042698 28 28 0,000 0,0281426 0,0363462 ! peptidyl-tyrosine modification GO:0018212 29 28 0,000 0,0281426 0,03633306 ! deoxyribonuclease activity GO:0004536 28 28 0,000 0,0281426 0,03631992 ! cofactor catabolic process GO:0051187 30 28 0,000 0,0281426 0,0363068 ! DNA damage checkpoint GO:0000077 31 28 0,000 0,0281426 0,03629369 ! negative regulation of actin filament polymerization GO:0030837 28 28 0,000 0,0281426 0,03628059 ! cortical cytoskeleton GO:0030863 29 28 0,000 0,0281426 0,0362675 ! icosanoid biosynthetic process GO:0046456 29 28 0,000 0,0281426 0,03625441 ! amino sugar metabolic process GO:0006040 28 28 0,000 0,0281426 0,03624134 ! membrane docking GO:0022406 28 28 0,000 0,0281426 0,03622827 ! sister chromatid segregation GO:0000819 28 28 0,000 0,0281426 0,03621522 ! detection of light stimulus involved in sensory perception GO:0050962 28 28 0,000 0,0281426 0,03620217 GO:0050908|detection of light stimulus involved in visual perception, ! cell junction assembly GO:0034329 30 28 0,000 0,0281426 0,03618914 ! complement activation, classical pathway GO:0006958 31 28 0,000 0,0281426 0,03617611 ! multicellular organismal catabolic process GO:0044243 28 28 0,000 0,0281426 0,03616309 ! response to mechanical stimulus GO:0009612 28 28 0,000 0,0281426 0,03615008 ! caspase regulator activity GO:0043028 28 28 0,000 0,0281426 0,03613708 ! ensheathment of neurons GO:0007272 29 28 0,000 0,0281426 0,03612409 GO:0008366|axon ensheathment, ! DNA polymerase activity GO:0034061 29 28 0,000 0,0281426 0,03611111 ! calcium-mediated signaling GO:0019722 28 28 0,000 0,0281426 0,03609814 ! neurotransmitter secretion GO:0007269 29 28 0,000 0,0281426 0,03608518 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 28 28 0,000 0,0281426 0,03607223 ! glycogen metabolic process GO:0005977 29 28 0,000 0,0281426 0,03605929 ! RNA helicase activity GO:0003724 28 28 0,000 0,0281426 0,03604635 ! Rho GTPase activator activity GO:0005100 32 28 0,000 0,0281426 0,03603343 ! symbiosis, encompassing mutualism through parasitism GO:0044403 32 28 0,000 0,0281426 0,03602051 ! transferase activity, transferring nitrogenous groups GO:0016769 30 29 0,000 0,02913389 0,03727593 ! spliceosomal snRNP biogenesis GO:0000387 30 29 0,000 0,02913389 0,03726258 ! odontogenesis of dentine-containing tooth GO:0042475 30 29 0,000 0,02913389 0,03724924 ! scavenger receptor activity GO:0005044 30 29 0,000 0,02913389 0,0372359 ! mesoderm morphogenesis GO:0048332 30 29 0,000 0,02913389 0,03722258 ! male gonad development GO:0008584 29 29 0,000 0,02913389 0,03720927 ! response to organic cyclic substance GO:0014070 31 29 0,000 0,02913389 0,03719597 ! negative regulation of MAP kinase activity GO:0043407 30 29 0,000 0,02913389 0,03718267 ! sterol biosynthetic process GO:0016126 30 29 0,000 0,02913389 0,03716939 ! endocytic vesicle GO:0030139 29 29 0,000 0,02913389 0,03715611 ! Rho GTPase binding GO:0017048 32 29 0,000 0,02913389 0,03714285 ! serine family amino acid metabolic process GO:0009069 30 29 0,000 0,02913389 0,03712959 ! fatty acid catabolic process GO:0009062 30 29 0,000 0,02913389 0,03711634 ! regulation of calcium ion transport GO:0051924 32 29 0,000 0,02913389 0,03710311 ! negative regulation of protein polymerization GO:0032272 29 29 0,000 0,02913389 0,03708988 ! glucan metabolic process GO:0044042 30 29 0,000 0,02913389 0,03707666 GO:0006073|cellular glucan metabolic process, ! regulation of synaptic plasticity GO:0048167 29 29 0,000 0,02913389 0,03706345 ! proteoglycan metabolic process GO:0006029 30 29 0,000 0,02913389 0,03705025 ! xenobiotic metabolic process GO:0006805 29 29 0,000 0,02913389 0,03703706 ! negative regulation of response to external stimulus GO:0032102 29 29 0,000 0,02913389 0,03702388 ! positive regulation of T cell proliferation GO:0042102 33 29 0,000 0,02913389 0,03701071 ! steroid dehydrogenase activity GO:0016229 29 29 0,000 0,02913389 0,03699755 ! regulation of protein import into nucleus GO:0042306 30 29 0,000 0,02913389 0,0369844 ! clathrin coated vesicle membrane GO:0030665 32 29 0,000 0,02913389 0,03697126 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 30 29 0,000 0,02913389 0,03695812 ! cytosolic small ribosomal subunit GO:0022627 29 29 0,000 0,02913389 0,036945 ! detection of visible light GO:0009584 29 29 0,000 0,02913389 0,03693188 ! tumor necrosis factor receptor superfamily binding GO:0032813 29 29 0,000 0,02913389 0,03691878 ! acetylglucosaminyltransferase activity GO:0008375 30 29 0,000 0,02913389 0,03690568 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,02913389 0,03689259 ! gene silencing GO:0016458 29 29 0,000 0,02913389 0,03687952 ! hormone binding GO:0042562 30 30 0,000 0,03012423 0,03811964 ! negative regulation of DNA metabolic process GO:0051053 34 30 0,000 0,03012423 0,03810614 ! inner ear morphogenesis GO:0042472 31 30 0,000 0,03012423 0,03809264 ! GPI anchor biosynthetic process GO:0006506 32 30 0,000 0,03012423 0,03807916 ! acrosomal vesicle GO:0001669 32 30 0,000 0,03012423 0,03806569 ! negative regulation of DNA binding GO:0043392 31 30 0,000 0,03012423 0,03805222 ! triglyceride metabolic process GO:0006641 31 30 0,000 0,03012423 0,03803877 ! erythrocyte differentiation GO:0030218 32 30 0,000 0,03012423 0,03802532 ! ceramide metabolic process GO:0006672 30 30 0,000 0,03012423 0,03801188 ! cell fate specification GO:0001708 31 30 0,000 0,03012423 0,03799846 ! negative regulation of hydrolase activity GO:0051346 32 30 0,000 0,03012423 0,03798504 ! PDZ domain binding GO:0030165 32 30 0,000 0,03012423 0,03797163 ! AP-type membrane coat adaptor complex GO:0030119 31 30 0,000 0,03012423 0,03795823 GO:0030131|clathrin adaptor complex, ! embryonic epithelial tube formation GO:0001838 32 30 0,000 0,03012423 0,03794484 ! negative regulation of cell activation GO:0050866 31 30 0,000 0,03012423 0,03793146 ! negative regulation of protein transport GO:0051224 30 30 0,000 0,03012423 0,03791809 ! negative regulation of protein complex assembly GO:0031333 30 30 0,000 0,03012423 0,03790473 ! regulation of JAK-STAT cascade GO:0046425 32 30 0,000 0,03012423 0,03789138 ! drug binding GO:0008144 30 30 0,000 0,03012423 0,03787804 ! multicellular organismal macromolecule metabolic process GO:0044259 30 30 0,000 0,03012423 0,03786471 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 33 30 0,000 0,03012423 0,03785138 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03012423 0,03783807 ! regulation of systemic arterial blood pressure GO:0003073 32 30 0,000 0,03012423 0,03782476 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 31 30 0,000 0,03012423 0,03781147 ! aminopeptidase activity GO:0004177 32 30 0,000 0,03012423 0,03779818 ! detection of light stimulus GO:0009583 30 30 0,000 0,03012423 0,03778491 ! L-amino acid transmembrane transporter activity GO:0015179 30 30 0,000 0,03012423 0,03777164 ! cysteine-type endopeptidase inhibitor activity GO:0004869 32 30 0,000 0,03012423 0,03775838 ! negative regulation of cell adhesion GO:0007162 33 31 0,000 0,03111363 0,03898483 ! striated muscle cell differentiation GO:0051146 31 31 0,000 0,03111363 0,03897116 ! GPI anchor metabolic process GO:0006505 33 31 0,000 0,03111363 0,0389575 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03111363 0,03894384 ! spliceosome assembly GO:0000245 32 31 0,000 0,03111363 0,03893019 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 32 31 0,000 0,03111363 0,03891656 GO:0004601|peroxidase activity, ! unsaturated fatty acid biosynthetic process GO:0006636 32 31 0,000 0,03111363 0,03890293 ! positive regulation of neurogenesis GO:0050769 32 31 0,000 0,03111363 0,03888932 ! cyclic nucleotide metabolic process GO:0009187 31 31 0,000 0,03111363 0,03887571 ! nucleotide catabolic process GO:0009166 32 31 0,000 0,03111363 0,03886211 ! replication fork GO:0005657 32 31 0,000 0,03111363 0,03884852 ! placenta development GO:0001890 31 31 0,000 0,03111363 0,03883494 ! condensed nuclear chromosome GO:0000794 32 31 0,000 0,03111363 0,03882138 ! regulation of pH GO:0006885 31 31 0,000 0,03111363 0,03880782 ! protein methyltransferase activity GO:0008276 36 31 0,000 0,03111363 0,03879427 ! acute-phase response GO:0006953 32 31 0,000 0,03111363 0,03878072 ! peptide transport GO:0015833 32 31 0,000 0,03111363 0,03876719 ! respiratory gaseous exchange GO:0007585 32 31 0,000 0,03111363 0,03875367 ! DNA integrity checkpoint GO:0031570 34 31 0,000 0,03111363 0,03874016 ! Golgi-associated vesicle membrane GO:0030660 34 31 0,000 0,03111363 0,03872666 ! regulation of protein stability GO:0031647 32 31 0,000 0,03111363 0,03871316 ! sarcolemma GO:0042383 33 31 0,000 0,03111363 0,03869968 ! vesicle localization GO:0051648 32 31 0,000 0,03111363 0,0386862 ! response to hydrogen peroxide GO:0042542 34 32 0,000 0,03210209 0,03990134 ! DNA helicase activity GO:0003678 34 32 0,000 0,03210209 0,03988746 ! NADP or NADPH binding GO:0050661 33 32 0,000 0,03210209 0,03987359 ! pigment biosynthetic process GO:0046148 34 32 0,000 0,03210209 0,03985972 ! purinergic nucleotide receptor activity GO:0001614 34 32 0,000 0,03210209 0,03984587 GO:0016502|nucleotide receptor activity, ! female gonad development GO:0008585 32 32 0,000 0,03210209 0,03983202 ! late endosome membrane GO:0031902 32 32 0,000 0,03210209 0,03981819 ! positive regulation of cell development GO:0010720 33 32 0,000 0,03210209 0,03980436 ! hindbrain development GO:0030902 35 32 0,000 0,03210209 0,03979054 ! aerobic respiration GO:0009060 32 32 0,000 0,03210209 0,03977674 ! positive regulation of catabolic process GO:0009896 34 32 0,000 0,03210209 0,03976294 ! regulation of muscle development GO:0048634 33 32 0,000 0,03210209 0,03974915 GO:0016202|regulation of striated muscle tissue development, ! cation:sugar symporter activity GO:0005402 32 32 0,000 0,03210209 0,03973538 GO:0005351|sugar:hydrogen symporter activity, ! sphingoid metabolic process GO:0046519 32 32 0,000 0,03210209 0,03972161 ! response to ionizing radiation GO:0010212 33 32 0,000 0,03210209 0,03970785 ! flagellum GO:0019861 32 32 0,000 0,03210209 0,0396941 ! regulation of lymphocyte mediated immunity GO:0002706 36 32 0,000 0,03210209 0,03968036 ! I band GO:0031674 35 32 0,000 0,03210209 0,03966663 ! JAK-STAT cascade GO:0007259 34 32 0,000 0,03210209 0,03965291 ! double-stranded RNA binding GO:0003725 33 32 0,000 0,03210209 0,0396392 ! cellular response to insulin stimulus GO:0032869 37 32 0,000 0,03210209 0,0396255 ! adult locomotory behavior GO:0008344 33 32 0,000 0,03210209 0,0396118 ! pyrimidine nucleotide metabolic process GO:0006220 37 32 0,000 0,03210209 0,03959812 ! positive regulation of transcription factor activity GO:0051091 34 33 0,000 0,03308961 0,04080213 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 34 33 0,000 0,03308961 0,04078805 ! platelet alpha granule lumen GO:0031093 34 33 0,000 0,03308961 0,04077398 ! negative regulation of binding GO:0051100 34 33 0,000 0,03308961 0,04075991 ! organelle envelope lumen GO:0031970 34 33 0,000 0,03308961 0,04074586 ! vesicle coat GO:0030120 36 33 0,000 0,03308961 0,04073181 ! endoribonuclease activity GO:0004521 34 33 0,000 0,03308961 0,04071777 ! embryonic organ development GO:0048568 36 33 0,000 0,03308961 0,04070375 ! glial cell differentiation GO:0010001 33 33 0,000 0,03308961 0,04068973 ! tissue remodeling GO:0048771 35 33 0,000 0,03308961 0,04067572 ! segmentation GO:0035282 34 33 0,000 0,03308961 0,04066173 ! positive regulation of gene-specific transcription GO:0043193 34 33 0,000 0,03308961 0,04064774 ! energy coupled proton transport, down electrochemical gradient GO:0015985 33 33 0,000 0,03308961 0,04063376 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03308961 0,04061979 ! hormone biosynthetic process GO:0042446 33 33 0,000 0,03308961 0,04060584 ! O-acyltransferase activity GO:0008374 33 33 0,000 0,03308961 0,04059189 ! response to xenobiotic stimulus GO:0009410 33 33 0,000 0,03308961 0,04057795 ! cellular amide metabolic process GO:0043603 34 34 0,000 0,03407618 0,04177344 ! sugar transmembrane transporter activity GO:0051119 34 34 0,000 0,03407618 0,04175911 GO:0015144|carbohydrate transmembrane transporter activity, ! neural tube development GO:0021915 36 34 0,000 0,03407618 0,04174478 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 34 0,000 0,03407618 0,04173047 ! neutral lipid metabolic process GO:0006638 35 34 0,000 0,03407618 0,04171616 GO:0006639|acylglycerol metabolic process, ! lipid homeostasis GO:0055088 34 34 0,000 0,03407618 0,04170187 ! telencephalon development GO:0021537 34 34 0,000 0,03407618 0,04168758 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 35 34 0,000 0,03407618 0,0416733 ! integral to Golgi membrane GO:0030173 34 34 0,000 0,03407618 0,04165904 ! intramolecular oxidoreductase activity GO:0016860 35 34 0,000 0,03407618 0,04164478 ! collagen GO:0005581 35 34 0,000 0,03407618 0,04163053 ! development of primary female sexual characteristics GO:0046545 34 34 0,000 0,03407618 0,04161629 GO:0046660|female sex differentiation, ! DNA-directed RNA polymerase activity GO:0003899 35 34 0,000 0,03407618 0,04160207 GO:0034062|RNA polymerase activity, ! leukocyte chemotaxis GO:0030595 35 34 0,000 0,03407618 0,04158785 GO:0060326|cell chemotaxis, ! sodium channel activity GO:0005272 36 34 0,000 0,03407618 0,04157364 ! carboxypeptidase activity GO:0004180 35 34 0,000 0,03407618 0,04155944 ! spermatid development GO:0007286 34 34 0,000 0,03407618 0,04154525 ! BMP signaling pathway GO:0030509 35 34 0,000 0,03407618 0,04153107 ! specific RNA polymerase II transcription factor activity GO:0003704 35 34 0,000 0,03407618 0,0415169 ! mitotic cell cycle checkpoint GO:0007093 35 35 0,000 0,03506182 0,04270319 ! regulation of intracellular protein transport GO:0033157 37 35 0,000 0,03506182 0,04268863 ! vesicle lumen GO:0031983 37 35 0,000 0,03506182 0,04267408 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! metanephros development GO:0001656 35 35 0,000 0,03506182 0,04265954 ! regulation of action potential in neuron GO:0019228 38 35 0,000 0,03506182 0,04264501 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 39 35 0,000 0,03506182 0,04263049 ! cytokine production GO:0001816 35 35 0,000 0,03506182 0,04261598 ! carbon-carbon lyase activity GO:0016830 35 35 0,000 0,03506182 0,04260148 ! embryonic pattern specification GO:0009880 36 35 0,000 0,03506182 0,04258699 ! regulation of metal ion transport GO:0010959 38 35 0,000 0,03506182 0,04257251 ! energy reserve metabolic process GO:0006112 36 35 0,000 0,03506182 0,04255804 ! metalloexopeptidase activity GO:0008235 36 35 0,000 0,03506182 0,04254358 ! protein serine/threonine phosphatase complex GO:0008287 38 35 0,000 0,03506182 0,04252913 ! phagocytosis GO:0006909 37 35 0,000 0,03506182 0,04251469 ! regulation of ARF protein signal transduction GO:0032012 40 35 0,000 0,03506182 0,04250026 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 37 35 0,000 0,03506182 0,04248583 ! ion transmembrane transport GO:0034220 35 35 0,000 0,03506182 0,04247142 ! neuropeptide receptor activity GO:0008188 35 35 0,000 0,03506182 0,04245702 ! oxygen binding GO:0019825 36 35 0,000 0,03506182 0,04244263 ! regulation of leukocyte mediated immunity GO:0002703 39 35 0,000 0,03506182 0,04242825 ! erythrocyte homeostasis GO:0034101 37 35 0,000 0,03506182 0,04241387 ! peripheral nervous system development GO:0007422 37 35 0,000 0,03506182 0,04239951 ! female gamete generation GO:0007292 38 35 0,000 0,03506182 0,04238516 ! regulation of hormone secretion GO:0046883 38 36 0,000 0,03604652 0,04356078 ! monocarboxylic acid binding GO:0033293 37 36 0,000 0,03604652 0,04354604 ! polysaccharide biosynthetic process GO:0000271 36 36 0,000 0,03604652 0,04353132 ! regulation of axonogenesis GO:0050770 39 36 0,000 0,03604652 0,0435166 ! glycerol ether metabolic process GO:0006662 37 36 0,000 0,03604652 0,0435019 ! regulation of proteolysis GO:0030162 37 36 0,000 0,03604652 0,0434872 ! integral to endoplasmic reticulum membrane GO:0030176 36 36 0,000 0,03604652 0,04347251 ! regulation of adaptive immune response GO:0002819 40 36 0,000 0,03604652 0,04345784 ! oxidoreduction coenzyme metabolic process GO:0006733 37 36 0,000 0,03604652 0,04344317 ! isoprenoid metabolic process GO:0006720 37 36 0,000 0,03604652 0,04342851 ! spermatid differentiation GO:0048515 36 36 0,000 0,03604652 0,04341386 ! phosphoinositide biosynthetic process GO:0046489 38 36 0,000 0,03604652 0,04339923 ! ER to Golgi vesicle-mediated transport GO:0006888 36 36 0,000 0,03604652 0,0433846 ! condensed chromosome kinetochore GO:0000777 37 36 0,000 0,03604652 0,04336998 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 38 36 0,000 0,03604652 0,04335537 ! neuropeptide binding GO:0042923 36 36 0,000 0,03604652 0,04334078 ! organic anion transport GO:0015711 37 36 0,000 0,03604652 0,04332619 ! carbohydrate homeostasis GO:0033500 38 36 0,000 0,03604652 0,04331161 GO:0042593|glucose homeostasis, ! complement activation GO:0006956 39 36 0,000 0,03604652 0,04329704 ! antigen binding GO:0003823 36 36 0,000 0,03604652 0,04328248 ! extrinsic to plasma membrane GO:0019897 36 36 0,000 0,03604652 0,04326794 ! cytokinesis GO:0000910 40 36 0,000 0,03604652 0,0432534 ! coated pit GO:0005905 42 36 0,000 0,03604652 0,04323887 ! protein amino acid N-linked glycosylation GO:0006487 40 37 0,000 0,03703028 0,044404 ! ribonucleoside metabolic process GO:0009119 43 37 0,000 0,03703028 0,0443891 ! DNA-dependent ATPase activity GO:0008094 39 37 0,000 0,03703028 0,0443742 ! regulation of T cell differentiation GO:0045580 41 37 0,000 0,03703028 0,04435931 ! biopolymer methylation GO:0043414 42 37 0,000 0,03703028 0,04434444 ! intrinsic to Golgi membrane GO:0031228 37 37 0,000 0,03703028 0,04432957 ! protein homooligomerization GO:0051260 38 37 0,000 0,03703028 0,04431472 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 38 37 0,000 0,03703028 0,04429987 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 41 37 0,000 0,03703028 0,04428504 ! regulation of T cell proliferation GO:0042129 41 37 0,000 0,03703028 0,04427021 ! multicellular organismal metabolic process GO:0044236 38 37 0,000 0,03703028 0,04425539 ! amino acid binding GO:0016597 40 37 0,000 0,03703028 0,04424059 ! maintenance of protein location GO:0045185 38 37 0,000 0,03703028 0,04422579 ! maintenance of location in cell GO:0051651 38 37 0,000 0,03703028 0,044211 ! solute:hydrogen symporter activity GO:0015295 37 37 0,000 0,03703028 0,04419623 ! proton-transporting two-sector ATPase complex GO:0016469 37 37 0,000 0,03703028 0,04418146 ! ear morphogenesis GO:0042471 39 38 0,000 0,0380131 0,04533894 ! odontogenesis GO:0042476 40 38 0,000 0,0380131 0,0453238 ! organic ether metabolic process GO:0018904 39 38 0,000 0,0380131 0,04530867 ! monovalent inorganic cation homeostasis GO:0055067 39 38 0,000 0,0380131 0,04529355 ! positive regulation of DNA binding GO:0043388 39 38 0,000 0,0380131 0,04527844 ! B cell differentiation GO:0030183 40 38 0,000 0,0380131 0,04526335 ! clathrin coat GO:0030118 43 38 0,000 0,0380131 0,04524826 ! regulation of endocytosis GO:0030100 39 38 0,000 0,0380131 0,04523318 ! dorsal/ventral pattern formation GO:0009953 38 38 0,000 0,0380131 0,04521811 ! cell growth GO:0016049 40 38 0,000 0,0380131 0,04520306 ! positive regulation of defense response GO:0031349 38 38 0,000 0,0380131 0,04518801 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 38 0,000 0,0380131 0,04517297 ! condensed chromosome, centromeric region GO:0000779 39 38 0,000 0,0380131 0,04515794 ! learning GO:0007612 42 38 0,000 0,0380131 0,04514292 ! negative regulation of protein complex disassembly GO:0043242 40 38 0,000 0,0380131 0,04512792 ! monocarboxylic acid transport GO:0015718 39 38 0,000 0,0380131 0,04511292 ! endosome transport GO:0016197 40 38 0,000 0,0380131 0,04509793 ! hormone-mediated signaling GO:0009755 39 38 0,000 0,0380131 0,04508295 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 40 38 0,000 0,0380131 0,04506799 ! N-methyltransferase activity GO:0008170 42 38 0,000 0,0380131 0,04505303 ! cytosolic large ribosomal subunit GO:0022625 38 38 0,000 0,0380131 0,04503808 ! pigment metabolic process GO:0042440 42 38 0,000 0,0380131 0,04502314 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 38 38 0,000 0,0380131 0,04500821 ! RNA modification GO:0009451 39 38 0,000 0,0380131 0,0449933 ! regulation of nucleocytoplasmic transport GO:0046822 41 39 0,000 0,03899498 0,04614019 ! Notch signaling pathway GO:0007219 41 39 0,000 0,03899498 0,04612491 ! induction of apoptosis by extracellular signals GO:0008624 39 39 0,000 0,03899498 0,04610963 ! keratin filament GO:0045095 41 39 0,000 0,03899498 0,04609437 ! ER-Golgi intermediate compartment GO:0005793 42 39 0,000 0,03899498 0,04607912 ! peroxisomal membrane GO:0005778 40 39 0,000 0,03899498 0,04606387 GO:0031903|microbody membrane, ! mitochondrial respiratory chain complex I GO:0005747 39 39 0,000 0,03899498 0,04604864 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! actin filament binding GO:0051015 39 39 0,000 0,03899498 0,04603342 ! regulation of protein secretion GO:0050708 41 39 0,000 0,03899498 0,04601821 ! cis-trans isomerase activity GO:0016859 39 39 0,000 0,03899498 0,046003 ! regulation of cell morphogenesis involved in differentiation GO:0010769 42 39 0,000 0,03899498 0,04598781 ! viral infectious cycle GO:0019058 39 39 0,000 0,03899498 0,04597263 ! mammary gland development GO:0030879 41 39 0,000 0,03899498 0,04595746 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 39 39 0,000 0,03899498 0,04594229 ! amine receptor activity GO:0008227 41 39 0,000 0,03899498 0,04592714 ! positive regulation of response to external stimulus GO:0032103 39 39 0,000 0,03899498 0,045912 ! monosaccharide binding GO:0048029 39 39 0,000 0,03899498 0,04589687 ! NADH dehydrogenase (ubiquinone) activity GO:0008137 39 39 0,000 0,03899498 0,04588174 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! peptide metabolic process GO:0006518 41 40 0,000 0,03997594 0,04702044 ! regulation of Rab protein signal transduction GO:0032483 41 40 0,000 0,03997594 0,04700496 GO:0032313|regulation of Rab GTPase activity, ! T cell differentiation GO:0030217 45 40 0,000 0,03997594 0,04698949 ! regulation of multicellular organism growth GO:0040014 42 40 0,000 0,03997594 0,04697403 ! neuron migration GO:0001764 42 40 0,000 0,03997594 0,04695857 ! nuclear export GO:0051168 42 40 0,000 0,03997594 0,04694313 ! inositol or phosphatidylinositol kinase activity GO:0004428 42 40 0,000 0,03997594 0,0469277 ! structural constituent of muscle GO:0008307 43 40 0,000 0,03997594 0,04691228 ! gliogenesis GO:0042063 40 40 0,000 0,03997594 0,04689687 ! feeding behavior GO:0007631 40 40 0,000 0,03997594 0,04688147 ! protein serine/threonine phosphatase activity GO:0004722 42 40 0,000 0,03997594 0,04686608 ! nucleus organization GO:0006997 40 40 0,000 0,03997594 0,04685069 ! positive regulation of cytokine biosynthetic process GO:0042108 41 40 0,000 0,03997594 0,04683532 ! sulfur compound biosynthetic process GO:0044272 41 40 0,000 0,03997594 0,04681996 ! inorganic anion transmembrane transporter activity GO:0015103 42 40 0,000 0,03997594 0,04680461 ! chromatin remodeling GO:0006338 43 40 0,000 0,03997594 0,04678927 ! response to insulin stimulus GO:0032868 45 40 0,000 0,03997594 0,04677394 ! activation of adenylate cyclase activity GO:0007190 42 41 0,000 0,04095595 0,04790492 ! positive regulation of binding GO:0051099 42 41 0,000 0,04095595 0,04788923 ! response to reactive oxygen species GO:0000302 43 41 0,000 0,04095595 0,04787355 ! solute:sodium symporter activity GO:0015370 41 41 0,000 0,04095595 0,04785789 ! regulation of translational initiation GO:0006446 41 41 0,000 0,04095595 0,04784223 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 44 41 0,000 0,04095595 0,04782659 GO:0046328|regulation of JNK cascade, ! mesenchymal cell development GO:0014031 43 41 0,000 0,04095595 0,04781095 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! heterocycle biosynthetic process GO:0018130 43 41 0,000 0,04095595 0,04779533 ! exonuclease activity GO:0004527 42 41 0,000 0,04095595 0,04777971 ! regulation of myeloid cell differentiation GO:0045637 43 41 0,000 0,04095595 0,04776411 ! positive regulation of cytokine production GO:0001819 42 41 0,000 0,04095595 0,04774852 ! hydro-lyase activity GO:0016836 44 41 0,000 0,04095595 0,04773293 ! positive regulation of protein transport GO:0051222 44 41 0,000 0,04095595 0,04771736 ! receptor-mediated endocytosis GO:0006898 43 41 0,000 0,04095595 0,0477018 ! regulation of neuron projection development GO:0010975 44 41 0,000 0,04095595 0,04768624 ! metal cluster binding GO:0051540 43 41 0,000 0,04095595 0,0476707 GO:0051536|iron-sulfur cluster binding, ! embryonic skeletal system morphogenesis GO:0048704 42 41 0,000 0,04095595 0,04765517 ! development of primary male sexual characteristics GO:0046546 41 41 0,000 0,04095595 0,04763964 ! Rab GTPase activator activity GO:0005097 42 41 0,000 0,04095595 0,04762413 ! RNA catabolic process GO:0006401 44 42 0,000 0,04193503 0,04874675 ! organellar ribosome GO:0000313 43 42 0,000 0,04193503 0,04873089 GO:0005761|mitochondrial ribosome, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 44 42 0,000 0,04193503 0,04871503 ! MHC protein complex GO:0042611 42 42 0,000 0,04193503 0,04869919 ! regulation of epithelial cell proliferation GO:0050678 44 42 0,000 0,04193503 0,04868336 ! negative regulation of cell migration GO:0030336 44 42 0,000 0,04193503 0,04866754 ! positive regulation of growth GO:0045927 42 42 0,000 0,04193503 0,04865173 ! icosanoid metabolic process GO:0006690 43 42 0,000 0,04193503 0,04863592 ! chemokine activity GO:0008009 42 42 0,000 0,04193503 0,04862013 ! ruffle GO:0001726 44 42 0,000 0,04193503 0,04860435 ! pigmentation GO:0043473 46 42 0,000 0,04193503 0,04858858 ! developmental growth GO:0048589 42 42 0,000 0,04193503 0,04857282 ! methylation GO:0032259 47 42 0,000 0,04193503 0,04855707 ! glycolysis GO:0006096 42 42 0,000 0,04193503 0,04854133 ! morphogenesis of embryonic epithelium GO:0016331 44 42 0,000 0,04193503 0,0485256 ! regulation of tube size GO:0035150 44 42 0,000 0,04193503 0,04850988 GO:0050880|regulation of blood vessel size, ! branching morphogenesis of a tube GO:0048754 43 42 0,000 0,04193503 0,04849417 ! general RNA polymerase II transcription factor activity GO:0016251 44 42 0,000 0,04193503 0,04847848 ! cellular amino acid derivative biosynthetic process GO:0042398 43 42 0,000 0,04193503 0,04846279 ! positive regulation of adenylate cyclase activity GO:0045762 44 43 0,000 0,04291318 0,04957715 ! transferase activity, transferring pentosyl groups GO:0016763 45 43 0,000 0,04291318 0,04956112 ! keratinocyte differentiation GO:0030216 46 43 0,000 0,04291318 0,0495451 ! epithelial cell differentiation GO:0030855 45 43 0,000 0,04291318 0,04952908 ! detection of stimulus involved in sensory perception GO:0050906 43 43 0,000 0,04291318 0,04951308 ! sulfotransferase activity GO:0008146 44 43 0,000 0,04291318 0,04949709 ! cellular polysaccharide metabolic process GO:0044264 44 43 0,000 0,04291318 0,0494811 ! channel regulator activity GO:0016247 46 43 0,000 0,04291318 0,04946513 ! histone modification GO:0016570 44 43 0,000 0,04291318 0,04944917 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 45 43 0,000 0,04291318 0,04943322 ! synaptosome GO:0019717 47 43 0,000 0,04291318 0,04941728 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 45 44 0,000 0,0438904 0,05052631 ! platelet alpha granule GO:0031091 46 44 0,000 0,0438904 0,05051003 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 44 44 0,000 0,0438904 0,05049376 ! regulation of ossification GO:0030278 48 44 0,000 0,0438904 0,0504775 ! cell recognition GO:0008037 46 44 0,000 0,0438904 0,05046124 ! positive regulation of cyclase activity GO:0031281 45 44 0,000 0,0438904 0,050445 ! regulation of lymphocyte differentiation GO:0045619 48 44 0,000 0,0438904 0,05042877 ! regulation of actin filament polymerization GO:0030833 45 44 0,000 0,0438904 0,05041255 ! cellular component disassembly GO:0022411 45 44 0,000 0,0438904 0,05039634 ! regulation of protein complex disassembly GO:0043244 46 44 0,000 0,0438904 0,05038014 ! regulation of ion transport GO:0043269 47 44 0,000 0,0438904 0,05036395 ! inner ear development GO:0048839 46 44 0,000 0,0438904 0,05034778 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 48 44 0,000 0,0438904 0,05033161 ! amino acid transmembrane transporter activity GO:0015171 44 44 0,000 0,0438904 0,05031545 ! negative regulation of immune system process GO:0002683 49 44 0,000 0,0438904 0,0502993 ! chemokine receptor binding GO:0042379 44 44 0,000 0,0438904 0,05028317 ! regulation of action potential GO:0001508 50 45 0,000 0,04486669 0,05138516 ! regulation of gene-specific transcription GO:0032583 47 45 0,000 0,04486669 0,05136869 ! cellular amino acid biosynthetic process GO:0008652 47 45 0,000 0,04486669 0,05135223 ! response to temperature stimulus GO:0009266 45 45 0,000 0,04486669 0,05133577 ! nucleoside monophosphate biosynthetic process GO:0009124 50 45 0,000 0,04486669 0,05131933 ! positive regulation of lyase activity GO:0051349 46 45 0,000 0,04486669 0,0513029 ! regulation of neuron apoptosis GO:0043523 45 45 0,000 0,04486669 0,05128647 ! excretion GO:0007588 46 45 0,000 0,04486669 0,05127006 ! protein phosphatase regulator activity GO:0019888 49 45 0,000 0,04486669 0,05125366 ! JNK cascade GO:0007254 45 45 0,000 0,04486669 0,05123727 ! SH3/SH2 adaptor activity GO:0005070 48 45 0,000 0,04486669 0,05122089 ! regulation of cell shape GO:0008360 46 45 0,000 0,04486669 0,05120452 ! epithelial tube morphogenesis GO:0060562 47 45 0,000 0,04486669 0,05118816 ! microbody part GO:0044438 46 45 0,000 0,04486669 0,05117181 GO:0044439|peroxisomal part, ! auxiliary transport protein activity GO:0015457 50 46 0,000 0,04584204 0,05226754 ! ATP synthesis coupled electron transport GO:0042773 46 46 0,000 0,04584204 0,05225086 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of inflammatory response GO:0050727 46 46 0,000 0,04584204 0,05223419 ! transport vesicle GO:0030133 49 46 0,000 0,04584204 0,05221752 ! glutamine family amino acid metabolic process GO:0009064 49 46 0,000 0,04584204 0,05220087 ! synapse organization GO:0050808 51 46 0,000 0,04584204 0,05218423 ! nuclear matrix GO:0016363 49 46 0,000 0,04584204 0,0521676 ! striated muscle contraction GO:0006941 49 46 0,000 0,04584204 0,05215098 ! unsaturated fatty acid metabolic process GO:0033559 47 46 0,000 0,04584204 0,05213438 ! antioxidant activity GO:0016209 47 46 0,000 0,04584204 0,05211778 ! activation of caspase activity GO:0006919 49 46 0,000 0,04584204 0,05210119 ! aging GO:0007568 48 46 0,000 0,04584204 0,05208461 ! male sex differentiation GO:0046661 46 46 0,000 0,04584204 0,05206805 ! coated vesicle membrane GO:0030662 49 46 0,000 0,04584204 0,05205149 ! covalent chromatin modification GO:0016569 47 46 0,000 0,04584204 0,05203495 ! RNA elongation from RNA polymerase II promoter GO:0006368 48 46 0,000 0,04584204 0,05201841 ! protein amino acid lipidation GO:0006497 50 47 0,000 0,04681647 0,05310725 ! stress-activated protein kinase signaling pathway GO:0031098 47 47 0,000 0,04681647 0,05309038 ! carbohydrate transport GO:0008643 47 47 0,000 0,04681647 0,05307353 ! proteasome complex GO:0000502 48 47 0,000 0,04681647 0,05305668 ! immunoglobulin mediated immune response GO:0016064 50 47 0,000 0,04681647 0,05303985 ! phosphatase regulator activity GO:0019208 51 47 0,000 0,04681647 0,05302303 ! vascular process in circulatory system GO:0003018 49 47 0,000 0,04681647 0,05300622 ! lipid modification GO:0030258 49 48 0,000 0,04778997 0,05409127 ! cytokine-mediated signaling pathway GO:0019221 49 48 0,000 0,04778997 0,05407414 ! morphogenesis of a branching structure GO:0001763 49 48 0,000 0,04778997 0,05405701 ! epidermal cell differentiation GO:0009913 51 48 0,000 0,04778997 0,05403989 ! mitochondrial transport GO:0006839 49 48 0,000 0,04778997 0,05402278 ! viral reproductive process GO:0022415 52 48 0,000 0,04778997 0,05400569 ! leukocyte migration GO:0050900 49 48 0,000 0,04778997 0,0539886 ! neuromuscular process GO:0050905 49 48 0,000 0,04778997 0,05397153 ! gastrulation GO:0007369 50 48 0,000 0,04778997 0,05395446 ! detection of abiotic stimulus GO:0009582 48 48 0,000 0,04778997 0,05393741 ! heterocycle catabolic process GO:0046700 53 48 0,000 0,04778997 0,05392037 ! B cell mediated immunity GO:0019724 51 48 0,000 0,04778997 0,05390334 ! protein N-terminus binding GO:0047485 51 48 0,000 0,04778997 0,05388632 ! transferase activity, transferring sulfur-containing groups GO:0016782 50 49 0,000 0,04876254 0,0549656 ! single-stranded DNA binding GO:0003697 49 49 0,000 0,04876254 0,05494825 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 54 49 0,000 0,04876254 0,05493092 ! intrinsic to endoplasmic reticulum membrane GO:0031227 50 49 0,000 0,04876254 0,0549136 ! ribonuclease activity GO:0004540 50 49 0,000 0,04876254 0,05489629 ! positive regulation of organelle organization GO:0010638 49 49 0,000 0,04876254 0,05487898 ! water-soluble vitamin metabolic process GO:0006767 50 49 0,000 0,04876254 0,05486169 ! lamellipodium GO:0030027 53 49 0,000 0,04876254 0,05484441 ! negative regulation of cell motion GO:0051271 51 49 0,000 0,04876254 0,05482715 ! nucleosome GO:0000786 49 49 0,000 0,04876254 0,05480989 ! kinetochore GO:0000776 50 49 0,000 0,04876254 0,05479264 ! membrane fusion GO:0006944 51 49 0,000 0,04876254 0,05477541 ! endocrine system development GO:0035270 49 49 0,000 0,04876254 0,05475818 ! RNA elongation GO:0006354 51 49 0,000 0,04876254 0,05474097 ! glycosaminoglycan metabolic process GO:0030203 53 50 0,000 0,04973418 0,05581419 ! regulation of actin polymerization or depolymerization GO:0008064 51 50 0,000 0,04973418 0,05579665 ! basement membrane GO:0005604 51 50 0,000 0,04973418 0,05577913 ! regulation of intracellular transport GO:0032386 52 50 0,000 0,04973418 0,05576162 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,04973418 0,05574412 ! maintenance of location GO:0051235 51 50 0,000 0,04973418 0,05572662 ! nuclear periphery GO:0034399 53 50 0,000 0,04973418 0,05570914 ! cell redox homeostasis GO:0045454 51 50 0,000 0,04973418 0,05569167 ! integrin binding GO:0005178 53 50 0,000 0,04973418 0,05567422 ! regulation of DNA replication GO:0006275 56 50 0,000 0,04973418 0,05565677 ! amino acid activation GO:0043038 50 50 0,000 0,04973418 0,05563933 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of organelle localization GO:0051656 53 50 0,000 0,04973418 0,05562191 ! regulation of bone remodeling GO:0046850 55 51 0,000 0,05070489 0,05668979 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 52 51 0,000 0,05070489 0,05667204 ! late endosome GO:0005770 51 51 0,000 0,05070489 0,05665431 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 56 51 0,000 0,05070489 0,05663659 ! ligase activity, forming carbon-oxygen bonds GO:0016875 51 51 0,000 0,05070489 0,05661888 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! negative regulation of response to stimulus GO:0048585 55 51 0,000 0,05070489 0,05660118 ! carbon-oxygen lyase activity GO:0016835 54 51 0,000 0,05070489 0,05658349 ! skeletal muscle fiber development GO:0048741 54 51 0,000 0,05070489 0,05656582 ! lipoprotein biosynthetic process GO:0042158 54 51 0,000 0,05070489 0,05654815 ! heart morphogenesis GO:0003007 54 51 0,000 0,05070489 0,0565305 ! steroid hormone receptor activity GO:0003707 53 51 0,000 0,05070489 0,05651285 ! antiporter activity GO:0015297 52 51 0,000 0,05070489 0,05649522 ! respiratory electron transport chain GO:0022904 52 52 0,000 0,05167468 0,0575578 ! positive regulation of cell migration GO:0030335 55 52 0,000 0,05167468 0,05753985 ! Golgi-associated vesicle GO:0005798 55 52 0,000 0,05167468 0,05752191 ! sphingolipid metabolic process GO:0006665 53 52 0,000 0,05167468 0,05750399 ! cell maturation GO:0048469 55 52 0,000 0,05167468 0,05748607 ! regulation of protein polymerization GO:0032271 53 52 0,000 0,05167468 0,05746817 ! regulation of actin filament length GO:0030832 53 52 0,000 0,05167468 0,05745028 ! regulation of cell projection organization GO:0031344 55 52 0,000 0,05167468 0,0574324 ! chloride transport GO:0006821 53 52 0,000 0,05167468 0,05741453 ! positive regulation of caspase activity GO:0043280 55 52 0,000 0,05167468 0,05739667 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 55 52 0,000 0,05167468 0,05737882 ! regulation of muscle contraction GO:0006937 56 52 0,000 0,05167468 0,05736099 ! glucose catabolic process GO:0006007 52 52 0,000 0,05167468 0,05734316 ! generation of a signal involved in cell-cell signaling GO:0003001 54 52 0,000 0,05167468 0,05732535 ! small ribosomal subunit GO:0015935 52 52 0,000 0,05167468 0,05730755 ! cytokine receptor activity GO:0004896 53 52 0,000 0,05167468 0,05728975 ! activation of phospholipase C activity GO:0007202 55 53 0,000 0,05264355 0,05834578 GO:0010863|positive regulation of phospholipase C activity, ! nucleoside monophosphate metabolic process GO:0009123 58 53 0,000 0,05264355 0,05832768 ! nucleoside metabolic process GO:0009116 61 53 0,000 0,05264355 0,05830959 ! N-acetyltransferase activity GO:0008080 54 53 0,000 0,05264355 0,05829151 ! synaptic vesicle GO:0008021 57 53 0,000 0,05264355 0,05827344 ! pyridoxal phosphate binding GO:0030170 56 53 0,000 0,05264355 0,05825538 GO:0070279|vitamin B6 binding, ! viral reproduction GO:0016032 57 53 0,000 0,05264355 0,05823733 ! cell projection assembly GO:0030031 56 53 0,000 0,05264355 0,0582193 ! embryonic skeletal system development GO:0048706 54 53 0,000 0,05264355 0,05820127 ! proton transport GO:0015992 53 53 0,000 0,05264355 0,05818326 ! mRNA binding GO:0003729 55 53 0,000 0,05264355 0,05816526 ! single fertilization GO:0007338 55 53 0,000 0,05264355 0,05814727 ! axon GO:0030424 58 54 0,000 0,05361149 0,05919809 ! heat shock protein binding GO:0031072 54 54 0,000 0,05361149 0,05917979 ! regulation of neurotransmitter levels GO:0001505 60 54 0,000 0,05361149 0,05916151 ! double-stranded DNA binding GO:0003690 55 54 0,000 0,05361149 0,05914323 ! positive regulation of phospholipase activity GO:0010518 56 54 0,000 0,05361149 0,05912496 ! tRNA processing GO:0008033 55 54 0,000 0,05361149 0,05910671 ! growth factor receptor binding GO:0070851 56 54 0,000 0,05361149 0,05908847 ! regulation of protein catabolic process GO:0042176 57 54 0,000 0,05361149 0,05907024 ! DNA catabolic process GO:0006308 55 54 0,000 0,05361149 0,05905201 ! regulation of tissue remodeling GO:0034103 58 54 0,000 0,05361149 0,05903381 ! regulation of cellular component size GO:0032535 56 55 0,000 0,05457851 0,0600801 ! response to peptide hormone stimulus GO:0043434 60 55 0,000 0,05457851 0,06006159 ! hydrogen transport GO:0006818 55 55 0,000 0,05457851 0,06004309 ! glycerophospholipid biosynthetic process GO:0046474 59 55 0,000 0,05457851 0,06002459 ! nucleotide-excision repair GO:0006289 58 55 0,000 0,05457851 0,06000611 ! large ribosomal subunit GO:0015934 56 55 0,000 0,05457851 0,05998764 ! protein amino acid autophosphorylation GO:0046777 57 55 0,000 0,05457851 0,05996919 ! positive regulation of secretion GO:0051047 60 56 0,000 0,0555446 0,06101193 ! regulation of mitosis GO:0007088 56 56 0,000 0,0555446 0,06099317 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 58 56 0,000 0,0555446 0,06097442 ! coenzyme biosynthetic process GO:0009108 59 56 0,000 0,0555446 0,06095568 ! cellular amino acid catabolic process GO:0009063 59 56 0,000 0,0555446 0,06093695 ! cartilage development GO:0051216 59 56 0,000 0,0555446 0,06091824 ! regulation of protein complex assembly GO:0043254 57 56 0,000 0,0555446 0,06089953 ! receptor signaling protein serine/threonine kinase activity GO:0004702 58 56 0,000 0,0555446 0,06088084 ! mesoderm development GO:0007498 57 56 0,000 0,0555446 0,06086216 ! camera-type eye development GO:0043010 59 56 0,000 0,0555446 0,06084349 ! regulation of transcription factor activity GO:0051090 59 57 0,000 0,05650978 0,06188176 GO:0090046|regulation of transcription regulator activity, ! ear development GO:0043583 60 57 0,000 0,05650978 0,06186279 ! positive regulation of T cell activation GO:0050870 62 57 0,000 0,05650978 0,06184383 ! kidney development GO:0001822 60 57 0,000 0,05650978 0,06182488 ! positive regulation of lipase activity GO:0060193 59 57 0,000 0,05650978 0,06180595 ! integrin-mediated signaling pathway GO:0007229 61 57 0,000 0,05650978 0,06178702 ! adult behavior GO:0030534 60 57 0,000 0,05650978 0,06176811 ! myosin complex GO:0016459 59 57 0,000 0,05650978 0,06174921 ! regulation of angiogenesis GO:0045765 60 58 0,000 0,05747403 0,06278366 ! lysosomal membrane GO:0005765 59 58 0,000 0,05747403 0,06276446 ! extracellular matrix organization GO:0030198 59 58 0,000 0,05747403 0,06274527 ! positive regulation of cell motion GO:0051272 61 58 0,000 0,05747403 0,06272609 ! homeostasis of number of cells GO:0048872 62 58 0,000 0,05747403 0,06270693 ! regulation of vesicle-mediated transport GO:0060627 60 58 0,000 0,05747403 0,06268777 ! detection of external stimulus GO:0009581 59 58 0,000 0,05747403 0,06266863 ! secondary metabolic process GO:0019748 59 58 0,000 0,05747403 0,0626495 ! translation initiation factor activity GO:0003743 58 58 0,000 0,05747403 0,06263038 ! dendrite GO:0030425 61 59 0,000 0,05843737 0,06366072 ! molecular adaptor activity GO:0060090 65 59 0,000 0,05843737 0,0636413 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 60 59 0,000 0,05843737 0,0636219 GO:0051213|dioxygenase activity, ! embryonic limb morphogenesis GO:0030326 63 59 0,000 0,05843737 0,06360251 GO:0035113|embryonic appendage morphogenesis, ! ubiquitin thiolesterase activity GO:0004221 62 59 0,000 0,05843737 0,06358313 ! regulation of heart contraction GO:0008016 62 59 0,000 0,05843737 0,06356376 ! copper ion binding GO:0005507 61 59 0,000 0,05843737 0,06354441 ! activation of immune response GO:0002253 68 59 0,000 0,05843737 0,06352506 ! aminoglycan metabolic process GO:0006022 62 59 0,000 0,05843737 0,06350573 ! amine transmembrane transporter activity GO:0005275 59 59 0,000 0,05843737 0,06348641 ! chromatin remodeling complex GO:0016585 61 59 0,000 0,05843737 0,0634671 ! cell soma GO:0043025 63 59 0,000 0,05843737 0,06344781 ! regulation of homeostatic process GO:0032844 68 59 0,000 0,05843737 0,06342852 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 61 60 0,000 0,05939978 0,06445355 ! multicellular organism reproduction GO:0032504 62 60 0,000 0,05939978 0,06443397 GO:0048609|reproductive process in a multicellular organism, ! occluding junction GO:0070160 60 60 0,000 0,05939978 0,0644144 GO:0005923|tight junction, ! myeloid cell differentiation GO:0030099 64 60 0,000 0,05939978 0,06439485 ! oxygen and reactive oxygen species metabolic process GO:0006800 60 60 0,000 0,05939978 0,0643753 ! regulation of cytokine biosynthetic process GO:0042035 63 60 0,000 0,05939978 0,06435577 ! chloride channel activity GO:0005254 61 60 0,000 0,05939978 0,06433625 ! fertilization GO:0009566 64 61 0,000 0,06036128 0,06535783 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 65 61 0,000 0,06036128 0,06533802 ! gonad development GO:0008406 61 61 0,000 0,06036128 0,06531822 ! protein maturation by peptide bond cleavage GO:0051605 64 61 0,000 0,06036128 0,06529843 ! regulation of immune effector process GO:0002697 65 61 0,000 0,06036128 0,06527866 ! amine catabolic process GO:0009310 68 62 0,000 0,06132186 0,06629741 ! phosphoinositide metabolic process GO:0030384 66 62 0,000 0,06132186 0,06627735 ! glycerolipid biosynthetic process GO:0045017 66 62 0,000 0,06132186 0,06625729 ! coated membrane GO:0048475 67 62 0,000 0,06132186 0,06623725 GO:0030117|membrane coat, ! hexose catabolic process GO:0019320 63 62 0,000 0,06132186 0,06621722 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 63 62 0,000 0,06132186 0,06619721 ! extracellular ligand-gated ion channel activity GO:0005230 67 62 0,000 0,06132186 0,0661772 ! germ cell development GO:0007281 62 62 0,000 0,06132186 0,06615721 ! ligand-dependent nuclear receptor activity GO:0004879 65 62 0,000 0,06132186 0,06613723 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 70 63 0,000 0,06228152 0,06715197 ! mitochondrial respiratory chain GO:0005746 65 63 0,000 0,06228152 0,0671317 ! negative regulation of ligase activity GO:0051352 64 63 0,000 0,06228152 0,06711144 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein oligomerization GO:0051259 64 63 0,000 0,06228152 0,06709119 ! transition metal ion transport GO:0000041 65 63 0,000 0,06228152 0,06707096 ! appendage morphogenesis GO:0035107 67 63 0,000 0,06228152 0,06705074 GO:0035108|limb morphogenesis, ! activation of MAPK activity GO:0000187 69 63 0,000 0,06228152 0,06703053 ! cellular defense response GO:0006968 64 63 0,000 0,06228152 0,06701034 ! B cell activation GO:0042113 66 63 0,000 0,06228152 0,06699015 ! antigen processing and presentation GO:0019882 64 63 0,000 0,06228152 0,06696998 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 65 63 0,000 0,06228152 0,06694982 ! organelle localization GO:0051640 66 63 0,000 0,06228152 0,06692968 ! transforming growth factor beta receptor signaling pathway GO:0007179 67 64 0,000 0,06324027 0,06793953 ! lung development GO:0030324 65 64 0,000 0,06324027 0,0679191 ! respiratory chain GO:0070469 66 64 0,000 0,06324027 0,06789868 ! developmental maturation GO:0021700 67 64 0,000 0,06324027 0,06787827 ! amino acid transport GO:0006865 64 64 0,000 0,06324027 0,06785787 ! anion channel activity GO:0005253 65 64 0,000 0,06324027 0,06783749 ! cellular hormone metabolic process GO:0034754 65 65 0,000 0,0641981 0,06884427 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 65 0,000 0,0641981 0,0688236 ! nuclear pore GO:0005643 69 65 0,000 0,0641981 0,06880295 ! regulation of MAPKKK cascade GO:0043408 72 65 0,000 0,0641981 0,0687823 ! rhythmic process GO:0048511 66 65 0,000 0,0641981 0,06876167 ! regulation of lipase activity GO:0060191 67 65 0,000 0,0641981 0,06874105 ! adaptive immune response GO:0002250 68 65 0,000 0,0641981 0,06872045 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 69 65 0,000 0,0641981 0,06869985 GO:0060173|limb development, ! skeletal system morphogenesis GO:0048705 66 65 0,000 0,0641981 0,06867927 ! lipoprotein metabolic process GO:0042157 68 65 0,000 0,0641981 0,0686587 ! DNA-dependent DNA replication GO:0006261 66 65 0,000 0,0641981 0,06863815 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 71 66 0,000 0,06515502 0,0696404 ! endoplasmic reticulum lumen GO:0005788 66 66 0,000 0,06515502 0,06961956 ! urogenital system development GO:0001655 69 66 0,000 0,06515502 0,06959873 ! amine binding GO:0043176 70 66 0,000 0,06515502 0,06957792 ! response to nutrient GO:0007584 67 66 0,000 0,06515502 0,06955712 ! acetyltransferase activity GO:0016407 68 66 0,000 0,06515502 0,06953633 ! respiratory tube development GO:0030323 68 67 0,000 0,06611102 0,07053554 ! mRNA transport GO:0051028 70 67 0,000 0,06611102 0,07051447 ! intracellular protein transmembrane transport GO:0065002 70 67 0,000 0,06611102 0,07049342 ! activation of protein kinase activity GO:0032147 70 67 0,000 0,06611102 0,07047238 ! regulation of caspase activity GO:0043281 70 67 0,000 0,06611102 0,07045135 ! Ras GTPase binding GO:0017016 70 67 0,000 0,06611102 0,07043033 ! humoral immune response GO:0006959 70 67 0,000 0,06611102 0,07040932 ! nucleosome assembly GO:0006334 69 67 0,000 0,06611102 0,07038833 ! transcription initiation from RNA polymerase II promoter GO:0006367 71 67 0,000 0,06611102 0,07036735 ! muscle cell differentiation GO:0042692 68 68 0,000 0,06706611 0,07136266 ! fatty acid biosynthetic process GO:0006633 70 68 0,000 0,06706611 0,0713414 ! protein import into nucleus GO:0006606 72 68 0,000 0,06706611 0,07132016 ! lymphocyte differentiation GO:0030098 75 68 0,000 0,06706611 0,07129893 ! regulation of actin cytoskeleton organization GO:0032956 74 68 0,000 0,06706611 0,07127771 ! protein-DNA complex GO:0032993 69 68 0,000 0,06706611 0,0712565 ! learning or memory GO:0007611 72 68 0,000 0,06706611 0,0712353 ! chloride ion binding GO:0031404 70 68 0,000 0,06706611 0,07121412 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 71 68 0,000 0,06706611 0,07119295 ! chromatin assembly GO:0031497 70 68 0,000 0,06706611 0,0711718 ! extrinsic to membrane GO:0019898 68 68 0,000 0,06706611 0,07115065 ! calcium channel activity GO:0005262 73 68 0,000 0,06706611 0,07112952 ! ribonucleoprotein complex assembly GO:0022618 69 68 0,000 0,06706611 0,0711084 ! respiratory system development GO:0060541 69 68 0,000 0,06706611 0,07108729 ! N-acyltransferase activity GO:0016410 69 68 0,000 0,06706611 0,0710662 ! regulation of endopeptidase activity GO:0052548 72 69 0,000 0,06802029 0,07205591 ! sarcomere GO:0030017 75 69 0,000 0,06802029 0,07203454 ! cAMP-mediated signaling GO:0019933 72 69 0,000 0,06802029 0,07201318 ! axon guidance GO:0007411 74 69 0,000 0,06802029 0,07199184 ! focal adhesion GO:0005925 75 69 0,000 0,06802029 0,07197051 ! regulation of DNA binding GO:0051101 72 70 0,000 0,06897356 0,07295752 ! carboxylic acid transmembrane transporter activity GO:0046943 71 70 0,000 0,06897356 0,07293592 ! early endosome GO:0005769 79 70 0,000 0,06897356 0,07291433 ! response to hypoxia GO:0001666 76 70 0,000 0,06897356 0,07289275 ! nuclear import GO:0051170 74 70 0,000 0,06897356 0,07287118 ! female pregnancy GO:0007565 71 70 0,000 0,06897356 0,07284963 ! rRNA processing GO:0006364 70 70 0,000 0,06897356 0,07282809 ! cytosolic ribosome GO:0022626 70 70 0,000 0,06897356 0,07280656 ! cell-matrix adhesion GO:0007160 76 71 0,000 0,06992592 0,07379003 ! FAD binding GO:0050660 72 71 0,000 0,06992592 0,07376823 ! response to oxygen levels GO:0070482 77 71 0,000 0,06992592 0,07374645 ! mitochondrial outer membrane GO:0005741 75 71 0,000 0,06992592 0,07372467 ! defense response to bacterium GO:0042742 71 71 0,000 0,06992592 0,07370291 ! steroid biosynthetic process GO:0006694 72 71 0,000 0,06992592 0,07368117 ! monosaccharide catabolic process GO:0046365 72 71 0,000 0,06992592 0,07365943 ! regulation of synaptic transmission GO:0050804 73 71 0,000 0,06992592 0,07363771 ! reproductive structure development GO:0048608 71 71 0,000 0,06992592 0,073616 ! neurotransmitter transport GO:0006836 73 71 0,000 0,06992592 0,0735943 ! regulation of actin filament-based process GO:0032970 77 71 0,000 0,06992592 0,07357262 ! organic acid transmembrane transporter activity GO:0005342 72 71 0,000 0,06992592 0,07355095 ! phospholipase activity GO:0004620 75 71 0,000 0,06992592 0,07352929 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 75 71 0,000 0,06992592 0,07350765 ! amine biosynthetic process GO:0009309 75 72 0,000 0,07087737 0,0744859 ! elevation of cytosolic calcium ion concentration GO:0007204 77 72 0,000 0,07087737 0,07446399 ! acute inflammatory response GO:0002526 76 72 0,000 0,07087737 0,07444209 ! cholesterol metabolic process GO:0008203 74 72 0,000 0,07087737 0,0744202 ! lipid transporter activity GO:0005319 77 72 0,000 0,07087737 0,07439832 ! cell-substrate adherens junction GO:0005924 78 72 0,000 0,07087737 0,07437646 ! negative regulation of transport GO:0051051 74 73 0,000 0,07182791 0,07535179 ! vacuolar membrane GO:0005774 74 73 0,000 0,07182791 0,07532966 ! rRNA metabolic process GO:0016072 73 73 0,000 0,07182791 0,07530754 ! regulation of protein transport GO:0051223 77 73 0,000 0,07182791 0,07528544 GO:0070201|regulation of establishment of protein localization, ! exopeptidase activity GO:0008238 78 73 0,000 0,07182791 0,07526335 ! cytosolic calcium ion homeostasis GO:0051480 78 73 0,000 0,07182791 0,07524127 ! nucleosome organization GO:0034728 76 74 0,000 0,07277755 0,07621367 ! neuropeptide signaling pathway GO:0007218 79 74 0,000 0,07277755 0,07619133 ! pore complex GO:0046930 78 74 0,000 0,07277755 0,076169 ! regulation of peptidase activity GO:0052547 78 74 0,000 0,07277755 0,07614668 ! protein localization in nucleus GO:0034504 78 74 0,000 0,07277755 0,07612438 ! myofibril GO:0030016 80 74 0,000 0,07277755 0,07610209 ! regulation of blood pressure GO:0008217 76 74 0,000 0,07277755 0,07607981 ! apical junction complex GO:0043296 74 74 0,000 0,07277755 0,07605754 ! development of primary sexual characteristics GO:0045137 74 74 0,000 0,07277755 0,07603529 ! regulation of Rho protein signal transduction GO:0035023 79 74 0,000 0,07277755 0,07601305 ! cellular response to hormone stimulus GO:0032870 81 74 0,000 0,07277755 0,07599083 ! serine-type endopeptidase inhibitor activity GO:0004867 75 74 0,000 0,07277755 0,07596861 ! nuclear chromosome part GO:0044454 76 74 0,000 0,07277755 0,07594641 ! response to drug GO:0042493 77 75 0,000 0,07372628 0,07691397 ! small GTPase binding GO:0031267 78 75 0,000 0,07372628 0,07689151 ! regulation of catabolic process GO:0009894 80 75 0,000 0,07372628 0,07686906 ! cell-substrate junction GO:0030055 82 75 0,000 0,07372628 0,07684662 ! establishment of RNA localization GO:0051236 78 75 0,000 0,07372628 0,0768242 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! membrane lipid biosynthetic process GO:0046467 77 75 0,000 0,07372628 0,07680179 ! tube morphogenesis GO:0035239 79 75 0,000 0,07372628 0,07677939 ! cellular lipid catabolic process GO:0044242 77 75 0,000 0,07372628 0,07675701 ! cysteine-type endopeptidase activity GO:0004197 75 75 0,000 0,07372628 0,07673463 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 80 76 0,000 0,0746741 0,07769848 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 76 76 0,000 0,0746741 0,07767585 ! vitamin metabolic process GO:0006766 77 76 0,000 0,0746741 0,07765323 ! inorganic anion transport GO:0015698 78 76 0,000 0,0746741 0,07763063 ! chromosome, centromeric region GO:0000775 78 76 0,000 0,0746741 0,07760803 ! apicolateral plasma membrane GO:0016327 76 76 0,000 0,0746741 0,07758545 ! T cell activation GO:0042110 82 76 0,000 0,0746741 0,07756288 ! digestion GO:0007586 80 76 0,000 0,0746741 0,07754033 ! cell-substrate adhesion GO:0031589 81 76 0,000 0,0746741 0,07751779 ! contractile fiber part GO:0044449 82 76 0,000 0,0746741 0,07749526 ! RNA localization GO:0006403 80 77 0,000 0,07562101 0,07845515 ! nuclear speck GO:0016607 80 77 0,000 0,07562101 0,07843237 ! G-protein-coupled receptor binding GO:0001664 78 77 0,000 0,07562101 0,07840959 ! endonuclease activity GO:0004519 80 77 0,000 0,07562101 0,07838683 ! regulation of transmission of nerve impulse GO:0051969 79 77 0,000 0,07562101 0,07836408 ! hydrogen ion transmembrane transporter activity GO:0015078 78 77 0,000 0,07562101 0,07834135 ! extracellular matrix structural constituent GO:0005201 80 77 0,000 0,07562101 0,07831863 ! vacuolar part GO:0044437 78 77 0,000 0,07562101 0,07829592 ! thiolester hydrolase activity GO:0016790 81 78 0,000 0,07656702 0,07925242 ! potassium channel complex GO:0034705 81 78 0,000 0,07656702 0,07922945 GO:0008076|voltage-gated potassium channel complex, ! regulation of cell adhesion GO:0030155 82 78 0,000 0,07656702 0,0792065 ! cofactor biosynthetic process GO:0051188 81 78 0,000 0,07656702 0,07918356 ! blood coagulation GO:0007596 81 78 0,000 0,07656702 0,07916064 GO:0050817|coagulation, ! phospholipid biosynthetic process GO:0008654 83 79 0,000 0,07751213 0,08011456 ! biogenic amine metabolic process GO:0006576 85 79 0,000 0,07751213 0,08009138 ! phosphoric diester hydrolase activity GO:0008081 82 79 0,000 0,07751213 0,08006821 ! positive regulation of MAP kinase activity GO:0043406 85 79 0,000 0,07751213 0,08004506 ! regulation of neuron differentiation GO:0045664 82 79 0,000 0,07751213 0,08002192 ! regulation of T cell activation GO:0050863 84 79 0,000 0,07751213 0,07999879 ! exocytosis GO:0006887 81 79 0,000 0,07751213 0,07997568 ! nitrogen compound catabolic process GO:0044270 89 79 0,000 0,07751213 0,07995258 ! regulation of protein localization GO:0032880 83 79 0,000 0,07751213 0,07992949 ! GTPase binding GO:0051020 83 80 0,000 0,07845633 0,08087978 ! regulation of Ras GTPase activity GO:0032318 84 80 0,000 0,07845633 0,08085644 ! ATP biosynthetic process GO:0006754 85 80 0,000 0,07845633 0,08083311 ! one-carbon metabolic process GO:0006730 87 80 0,000 0,07845633 0,0808098 ! monooxygenase activity GO:0004497 82 80 0,000 0,07845633 0,0807865 ! contractile fiber GO:0043292 86 80 0,000 0,07845633 0,08076321 ! protein ubiquitination GO:0016567 86 80 0,000 0,07845633 0,08073993 ! sterol metabolic process GO:0016125 83 81 0,000 0,07939964 0,08168715 ! protein binding, bridging GO:0030674 86 81 0,000 0,07939964 0,08166362 ! regulation of neurological system process GO:0031644 83 81 0,000 0,07939964 0,08164011 ! protein transporter activity GO:0008565 85 82 0,000 0,08034204 0,08258533 ! positive regulation of immune response GO:0050778 91 82 0,000 0,08034204 0,08256156 ! regulation of defense response GO:0031347 82 82 0,000 0,08034204 0,08253781 ! carboxylesterase activity GO:0004091 86 82 0,000 0,08034204 0,08251407 ! transcription initiation GO:0006352 86 82 0,000 0,08034204 0,08249035 ! mitochondrion organization GO:0007005 86 83 0,000 0,08128354 0,08343303 ! organelle outer membrane GO:0031968 87 83 0,000 0,08128354 0,08340906 ! cell leading edge GO:0031252 90 83 0,000 0,08128354 0,0833851 ! SH3 domain binding GO:0017124 97 83 0,000 0,08128354 0,08336115 ! hemostasis GO:0007599 86 83 0,000 0,08128354 0,08333721 ! oxidative phosphorylation GO:0006119 83 83 0,000 0,08128354 0,08331329 ! heparin binding GO:0008201 90 83 0,000 0,08128354 0,08328939 ! amine transport GO:0015837 83 83 0,000 0,08128354 0,0832655 ! extracellular matrix part GO:0044420 85 83 0,000 0,08128354 0,08324162 ! phosphoinositide binding GO:0035091 90 83 0,000 0,08128354 0,08321775 ! Ras GTPase activator activity GO:0005099 89 84 0,000 0,08222414 0,08415661 ! regulation of membrane potential GO:0042391 92 84 0,000 0,08222414 0,08413249 ! transmembrane receptor protein kinase activity GO:0019199 88 85 0,000 0,08316384 0,08506963 ! outer membrane GO:0019867 89 85 0,000 0,08316384 0,08504527 ! neurotransmitter receptor activity GO:0030594 86 85 0,000 0,08316384 0,08502092 ! leukocyte differentiation GO:0002521 95 86 0,000 0,08410265 0,08595608 ! neurotransmitter binding GO:0042165 88 86 0,000 0,08410265 0,08593149 ! anion binding GO:0043168 89 86 0,000 0,08410265 0,08590691 ! sex differentiation GO:0007548 86 86 0,000 0,08410265 0,08588234 ! UDP-glycosyltransferase activity GO:0008194 91 86 0,000 0,08410265 0,08585779 ! spindle GO:0005819 89 87 0,000 0,08504055 0,08679046 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 93 87 0,000 0,08504055 0,08676566 ! protein processing GO:0016485 92 87 0,000 0,08504055 0,08674088 ! ATP-dependent helicase activity GO:0008026 92 88 0,000 0,08597756 0,08767158 GO:0070035|purine NTP-dependent helicase activity, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 89 88 0,000 0,08597756 0,08764655 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 89 88 0,000 0,08597756 0,08762154 ! skeletal muscle tissue development GO:0007519 92 88 0,000 0,08597756 0,08759654 GO:0060538|skeletal muscle organ development, ! lipase activity GO:0016298 92 88 0,000 0,08597756 0,08757156 ! detection of stimulus GO:0051606 90 88 0,000 0,08597756 0,08754659 ! carboxylic acid catabolic process GO:0046395 93 89 0,000 0,08691368 0,08847456 GO:0016054|organic acid catabolic process, ! sulfur metabolic process GO:0006790 90 89 0,000 0,08691368 0,08844934 ! negative regulation of multicellular organismal process GO:0051241 93 89 0,000 0,08691368 0,08842414 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 92 89 0,000 0,08691368 0,08839896 ! regulation of binding GO:0051098 93 90 0,000 0,0878489 0,08932472 ! intermediate filament GO:0005882 92 90 0,000 0,0878489 0,08929929 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 95 90 0,000 0,0878489 0,08927388 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! nuclear membrane GO:0031965 92 90 0,000 0,0878489 0,08924848 ! external side of plasma membrane GO:0009897 99 90 0,000 0,0878489 0,0892231 ! growth factor binding GO:0019838 92 90 0,000 0,0878489 0,08919773 ! adherens junction GO:0005912 96 90 0,000 0,0878489 0,08917238 ! ATP metabolic process GO:0046034 96 91 0,000 0,08878322 0,09009517 ! homophilic cell adhesion GO:0007156 93 91 0,000 0,08878322 0,09006957 ! ribonucleoside triphosphate biosynthetic process GO:0009201 97 91 0,000 0,08878322 0,09004399 ! protein modification by small protein conjugation GO:0032446 98 91 0,000 0,08878322 0,09001843 ! forebrain development GO:0030900 95 91 0,000 0,08878322 0,08999287 ! apical plasma membrane GO:0016324 96 91 0,000 0,08878322 0,08996734 ! intermediate filament cytoskeleton GO:0045111 93 91 0,000 0,08878322 0,08994181 ! structure-specific DNA binding GO:0043566 93 92 0,000 0,08971666 0,09086165 ! angiogenesis GO:0001525 95 92 0,000 0,08971666 0,09083589 ! glycerophospholipid metabolic process GO:0006650 98 92 0,000 0,08971666 0,09081014 ! nucleoside triphosphate biosynthetic process GO:0009142 98 92 0,000 0,08971666 0,09078441 ! clathrin-coated vesicle GO:0030136 100 92 0,000 0,08971666 0,09075869 ! protein tyrosine phosphatase activity GO:0004725 104 92 0,000 0,08971666 0,09073299 ! gland development GO:0048732 95 92 0,000 0,08971666 0,0907073 ! DNA packaging GO:0006323 94 92 0,000 0,08971666 0,09068163 ! anatomical structure homeostasis GO:0060249 96 93 0,000 0,0906492 0,09159827 ! receptor complex GO:0043235 97 93 0,000 0,0906492 0,09157236 ! voltage-gated potassium channel activity GO:0005249 99 93 0,000 0,0906492 0,09154646 ! hormone metabolic process GO:0042445 96 93 0,000 0,0906492 0,09152058 ! translational elongation GO:0006414 97 94 0,000 0,09158085 0,09243505 ! nucleotidyltransferase activity GO:0016779 96 94 0,000 0,09158085 0,09240893 ! metalloendopeptidase activity GO:0004222 105 94 0,000 0,09158085 0,09238282 ! protein maturation GO:0051604 99 94 0,000 0,09158085 0,09235674 ! solute:cation symporter activity GO:0015294 95 94 0,000 0,09158085 0,09233066 ! in utero embryonic development GO:0001701 97 95 0,000 0,0925116 0,09324271 ! carboxylic acid binding GO:0031406 99 95 0,000 0,0925116 0,0932164 ! regulation of response to external stimulus GO:0032101 97 95 0,000 0,0925116 0,09319011 ! response to virus GO:0009615 102 95 0,000 0,0925116 0,09316383 ! peroxisome GO:0005777 97 96 0,000 0,09344147 0,09407372 GO:0042579|microbody, ! integral to organelle membrane GO:0031301 96 96 0,000 0,09344147 0,09404721 ! translation factor activity, nucleic acid binding GO:0008135 99 96 0,000 0,09344147 0,09402071 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 97 96 0,000 0,09344147 0,09399422 ! cell fate commitment GO:0045165 98 96 0,000 0,09344147 0,09396775 ! response to nutrient levels GO:0031667 98 96 0,000 0,09344147 0,0939413 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 101 97 0,000 0,09437045 0,09484854 ! peptidyl-amino acid modification GO:0018193 99 97 0,000 0,09437045 0,09482185 ! anchoring junction GO:0070161 103 97 0,000 0,09437045 0,09479518 ! reproductive developmental process GO:0003006 97 97 0,000 0,09437045 0,09476852 ! regulation of GTPase activity GO:0043087 104 97 0,000 0,09437045 0,09474188 ! unfolded protein binding GO:0051082 100 98 0,000 0,09529854 0,09564673 ! polysaccharide metabolic process GO:0005976 102 98 0,000 0,09529854 0,09561986 ! protein modification by small protein conjugation or removal GO:0070647 105 98 0,000 0,09529854 0,095593 ! chromatin binding GO:0003682 102 99 0,000 0,09622574 0,09649596 ! nuclear chromosome GO:0000228 102 99 0,000 0,09622574 0,09646887 ! protein C-terminus binding GO:0008022 106 99 0,000 0,09622574 0,09644179 ! regulation of cellular component biogenesis GO:0044087 106 99 0,000 0,09622574 0,09641473 ! anterior/posterior pattern formation GO:0009952 102 99 0,000 0,09622574 0,09638769 ! Ras protein signal transduction GO:0007265 105 99 0,000 0,09622574 0,09636066 ! electron transport chain GO:0022900 102 100 0,000 0,09715205 0,097261 ! tRNA metabolic process GO:0006399 101 100 0,000 0,09715205 0,09723374 ! cytokine binding GO:0019955 101 100 0,000 0,09715205 0,0972065 ! regulation of cell morphogenesis GO:0022604 104 100 0,000 0,09715205 0,09717927 ! chromatin assembly or disassembly GO:0006333 104 100 0,000 0,09715205 0,09715205