pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3799-4-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 1,02E-11 2,492E-08 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 4,264E-10 5,209E-07 GO:0042267|natural killer cell mediated cytotoxicity, ! spindle organization GO:0007051 50 32 4,000 4,514E-10 3,676E-07 ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 1,003E-09 6,128E-07 ! cell killing GO:0001906 32 15 3,000 2,759E-09 1,348E-06 ! polyol catabolic process GO:0046174 9 5 2,000 1,767E-08 7,193E-06 GO:0019405|alditol catabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 2,534E-08 8,844E-06 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1,433E-07 4,377E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 3,208E-07 8,708E-05 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 5,018E-07 1,226E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 7,689E-07 1,708E-04 ! fructose metabolic process GO:0006000 25 16 2,000 9,8E-07 1,995E-04 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 1,308E-06 2,459E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 2,317E-06 4,044E-04 ! leukocyte mediated immunity GO:0002443 136 75 3,000 2,328E-06 3,791E-04 ! alditol metabolic process GO:0019400 44 26 2,000 4,511E-06 6,887E-04 ! osteoblast differentiation GO:0001649 63 26 2,000 4,511E-06 6,482E-04 ! sperm motility GO:0030317 37 28 2,000 5,674E-06 7,7E-04 ! hexose biosynthetic process GO:0019319 53 32 2,000 8,56E-06 1,101E-03 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,228E-05 1,5E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 1,335E-05 1,553E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,494E-05 1,659E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,964E-05 2,086E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 2,239E-05 2,279E-03 ! photoreceptor cell development GO:0042461 10 6 1,000 2,239E-05 2,188E-03 GO:0046530|photoreceptor cell differentiation, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,239E-05 2,104E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,422E-05 2,191E-03 ! polyol metabolic process GO:0019751 77 45 2,000 2,422E-05 2,113E-03 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 3,133E-05 2,639E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 4,174E-05 3,399E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,174E-05 3,289E-03 ! response to UV GO:0009411 120 55 2,000 4,439E-05 3,389E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 5,362E-05 3,969E-03 ! postreplication repair GO:0006301 25 9 1,000 5,362E-05 3,853E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 5,362E-05 3,743E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 6,697E-05 4,545E-03 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 6,697E-05 4,422E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 6,697E-05 4,305E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 8,179E-05 5,123E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 8,179E-05 4,995E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 8,385E-05 4,996E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 8,758E-05 5,094E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 9,807E-05 5,572E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 9,807E-05 5,445E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 9,943E-05 5,398E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 9,943E-05 5,281E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,158E-04 6,019E-03 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 1,158E-04 5,894E-03 ! regulation of DNA repair GO:0006282 23 13 1,000 1,158E-04 5,774E-03 ! positive regulation of ligase activity GO:0051351 130 77 2,000 1,214E-04 5,933E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 1,311E-04 6,278E-03 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,517E-04 7,129E-03 ! regulation of ligase activity GO:0051340 147 84 2,000 1,572E-04 7,247E-03 ! regulation of cyclase activity GO:0031279 168 85 2,000 1,628E-04 7,367E-03 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,686E-04 7,488E-03 ! regulation of lyase activity GO:0051339 169 86 2,000 1,686E-04 7,354E-03 ! alcohol catabolic process GO:0046164 142 87 2,000 1,744E-04 7,477E-03 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 1,777E-04 7,487E-03 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,866E-04 7,726E-03 ! positive regulation of protein modification process GO:0031401 156 90 2,000 1,928E-04 7,852E-03 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,993E-04 7,98E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,993E-04 7,851E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,013E-04 7,805E-03 ! membrane budding GO:0006900 42 17 1,000 2,013E-04 7,683E-03 ! bone development GO:0060348 206 92 2,000 2,058E-04 7,735E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 2,125E-04 7,864E-03 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 2,193E-04 7,996E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 2,262E-04 8,128E-03 ! centrosome cycle GO:0007098 26 18 1,000 2,263E-04 8,011E-03 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 2,48E-04 8,654E-03 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 2,527E-04 8,695E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,805E-04 9,519E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 2,805E-04 9,389E-03 ! cell-cell junction organization GO:0045216 43 20 1,000 2,805E-04 9,262E-03 ! microtubule-based transport GO:0010970 59 22 1,000 3,405E-04 0,01109263 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,405E-04 0,01094667 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,405E-04 0,01080451 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 3,727E-04 0,01167261 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 4,062E-04 0,01256268 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,412E-04 0,0134738 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,412E-04 0,01330745 ! microtubule organizing center organization GO:0031023 42 26 1,000 4,776E-04 0,0142294 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,776E-04 0,01405796 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 4,776E-04 0,0138906 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,776E-04 0,01372718 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,546E-04 0,01575532 ! fat cell differentiation GO:0045444 57 28 1,000 5,546E-04 0,01557422 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,952E-04 0,01652478 ! regulation of B cell activation GO:0050864 55 30 1,000 6,373E-04 0,01749242 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 6,807E-04 0,01847649 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 6,807E-04 0,01827346 ! eye morphogenesis GO:0048592 65 31 1,000 6,807E-04 0,01807483 ! protein targeting to membrane GO:0006612 75 36 1,000 9,186E-04 0,02413012 ! cell junction organization GO:0034330 96 37 1,000 9,703E-04 0,02521778 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 9,703E-04 0,02495233 ! regulation of microtubule-based process GO:0032886 86 37 1,000 9,703E-04 0,02469241 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 1,023E-03 0,02577524 ! meiosis I GO:0007127 74 38 1,000 1,023E-03 0,02551223 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 1,023E-03 0,02525453 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 1,078E-03 0,02633274 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 1,191E-03 0,02880632 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 1,309E-03 0,03136176 ! double-strand break repair GO:0006302 85 44 1,000 1,371E-03 0,03251065 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,629E-03 0,03827217 ! response to calcium ion GO:0051592 94 49 1,000 1,697E-03 0,03948974 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 1,697E-03 0,03911719 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 1,767E-03 0,04033458 ! response to estrogen stimulus GO:0043627 98 52 1,000 1,909E-03 0,04318799 ! vesicle organization GO:0016050 127 53 1,000 1,983E-03 0,04443499 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 1,983E-03 0,04403103 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 2,21E-03 0,04864939 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 2,701E-03 0,05892623 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 3,055E-03 0,06604219 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 3,055E-03 0,06546287 ! negative regulation of cell growth GO:0030308 142 67 1,000 3,146E-03 0,06683793 ! chromosome segregation GO:0007059 127 67 1,000 3,146E-03 0,06626174 ! regulation of cellular response to stress GO:0080135 142 68 1,000 3,239E-03 0,06763311 ! negative regulation of cell size GO:0045792 144 69 1,000 3,333E-03 0,06900762 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 3,333E-03 0,06842772 ! negative regulation of kinase activity GO:0033673 145 70 1,000 3,429E-03 0,06979856 ! cell cycle checkpoint GO:0000075 145 71 1,000 3,525E-03 0,07117232 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 3,525E-03 0,07058894 ! actin filament organization GO:0007015 167 72 1,000 3,623E-03 0,07195905 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,823E-03 0,07530985 ! negative regulation of transferase activity GO:0051348 155 74 1,000 3,823E-03 0,07470738 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 3,924E-03 0,07608534 ! eye development GO:0001654 155 75 1,000 3,924E-03 0,07548625 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 4,237E-03 0,08085988 ! steroid biosynthetic process GO:0006694 146 79 1,000 4,343E-03 0,08225257 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 4,343E-03 0,08161986 ! negative regulation of organelle organization GO:0010639 181 80 1,000 4,451E-03 0,08300859 ! meiosis GO:0007126 143 81 1,000 4,56E-03 0,08439917 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 4,56E-03 0,08376459 ! meiotic cell cycle GO:0051321 144 82 1,000 4,671E-03 0,08515125 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 4,782E-03 0,08653962 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 4,895E-03 0,08792962 ! negative regulation of growth GO:0045926 168 85 1,000 5,009E-03 0,08932115 ! positive regulation of cell activation GO:0050867 161 86 1,000 5,124E-03 0,09071412 GO:0002696|positive regulation of leukocyte activation, ! cellular respiration GO:0045333 143 88 1,000 5,358E-03 0,09417676 ! response to inorganic substance GO:0010035 173 90 1,000 5,597E-03 0,0976745 ! response to unfolded protein GO:0006986 139 90 1,000 5,597E-03 0,09698177 ! regulation of cell cycle process GO:0010564 161 90 1,000 5,597E-03 0,0962988 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,175E-03 0,10548555 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,175E-03 0,10475301 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,175E-03 0,10403057 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,175E-03 0,10331804 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,175E-03 0,10261519 ! neuron fate determination GO:0048664 7 5 0,000 6,175E-03 0,10192185 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,175E-03 0,10123781 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,175E-03 0,10056289 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,175E-03 0,09989691 ! polyol transport GO:0015791 12 5 0,000 6,175E-03 0,09923969 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,175E-03 0,09859107 ! response to superoxide GO:0000303 10 5 0,000 6,175E-03 0,09795087 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,175E-03 0,09731892 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,175E-03 0,09669508 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,175E-03 0,09607919 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,175E-03 0,0954711 ! female meiosis GO:0007143 10 5 0,000 6,175E-03 0,09487065 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,175E-03 0,09427771 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,175E-03 0,09369213 ! hypothalamus development GO:0021854 9 5 0,000 6,175E-03 0,09311379 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,175E-03 0,09254254 ! cobalt ion transport GO:0006824 11 5 0,000 6,175E-03 0,09197825 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,175E-03 0,09142081 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,175E-03 0,09087008 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,175E-03 0,09032595 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,175E-03 0,08978829 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,175E-03 0,089257 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,175E-03 0,08873196 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,175E-03 0,08821306 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,175E-03 0,08770019 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,175E-03 0,08719326 ! transposition GO:0032196 9 5 0,000 6,175E-03 0,08669215 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,175E-03 0,08619676 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,175E-03 0,08570701 ! negative chemotaxis GO:0050919 16 5 0,000 6,175E-03 0,08522279 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,175E-03 0,08474401 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,175E-03 0,08427058 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,175E-03 0,08380241 ! behavioral response to pain GO:0048266 10 5 0,000 6,175E-03 0,08333941 ! clathrin coat assembly GO:0048268 15 5 0,000 6,175E-03 0,0828815 ! Notch receptor processing GO:0007220 11 5 0,000 6,175E-03 0,0824286 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,175E-03 0,08198062 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,175E-03 0,08153748 ! micturition GO:0060073 9 5 0,000 6,175E-03 0,0810991 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,175E-03 0,08066542 ! copulation GO:0007620 9 5 0,000 6,175E-03 0,08023635 ! glial cell fate commitment GO:0021781 14 5 0,000 6,175E-03 0,07981182 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,175E-03 0,07939175 ! bioluminescence GO:0008218 9 5 0,000 6,175E-03 0,07897609 ! spermidine metabolic process GO:0008216 7 5 0,000 6,175E-03 0,07856476 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,175E-03 0,07815769 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,175E-03 0,07775481 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,175E-03 0,07735607 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,175E-03 0,07696139 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,175E-03 0,07657073 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,175E-03 0,07618401 ! grooming behavior GO:0007625 6 5 0,000 6,175E-03 0,07580117 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,175E-03 0,07542217 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,175E-03 0,07504693 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,175E-03 0,07467541 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,175E-03 0,07430755 ! response to protozoan GO:0001562 13 5 0,000 6,175E-03 0,0739433 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,175E-03 0,0735826 ! lymph vessel development GO:0001945 10 5 0,000 6,175E-03 0,0732254 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,175E-03 0,07287166 ! endochondral ossification GO:0001958 17 5 0,000 6,175E-03 0,07252131 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,175E-03 0,07217432 ! single strand break repair GO:0000012 8 5 0,000 6,175E-03 0,07183063 ! parathyroid gland development GO:0060017 14 5 0,000 6,175E-03 0,0714902 ! anagen GO:0042640 7 5 0,000 6,175E-03 0,07115299 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,175E-03 0,07081894 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,175E-03 0,07048801 ! cytokine secretion GO:0050663 15 5 0,000 6,175E-03 0,07016015 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,175E-03 0,06983534 ! ceramide catabolic process GO:0046514 7 5 0,000 6,175E-03 0,06951352 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,175E-03 0,06919465 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,175E-03 0,06887869 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,175E-03 0,06856561 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,175E-03 0,06825535 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,175E-03 0,0679479 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,175E-03 0,0676432 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,175E-03 0,06734122 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,175E-03 0,06704193 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,175E-03 0,06674528 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,175E-03 0,06645125 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,175E-03 0,06615979 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,175E-03 0,06587089 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,175E-03 0,06558449 ! microvillus organization GO:0032528 8 5 0,000 6,175E-03 0,06530058 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,175E-03 0,06501911 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,175E-03 0,06474006 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,175E-03 0,06446339 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,175E-03 0,06418908 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,175E-03 0,06391709 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,175E-03 0,0636474 ! polyol biosynthetic process GO:0046173 6 5 0,000 6,175E-03 0,06337997 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,175E-03 0,06311478 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,175E-03 0,06285181 ! muscle cell migration GO:0014812 8 5 0,000 6,175E-03 0,06259101 ! mitochondrial fission GO:0000266 8 5 0,000 6,175E-03 0,06233237 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,175E-03 0,06207586 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,175E-03 0,06182145 ! mRNA transcription GO:0009299 10 5 0,000 6,175E-03 0,06156912 ! nerve growth factor processing GO:0032455 9 5 0,000 6,175E-03 0,06131883 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,175E-03 0,06107058 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,175E-03 0,06082433 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,175E-03 0,06058005 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,175E-03 0,06033773 ! monocyte activation GO:0042117 10 5 0,000 6,175E-03 0,06009734 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,175E-03 0,05985886 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,175E-03 0,05962227 ! response to food GO:0032094 6 5 0,000 6,175E-03 0,05938753 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,175E-03 0,05915464 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,175E-03 0,05892357 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,175E-03 0,05869429 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,175E-03 0,0584668 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,175E-03 0,05824105 ! forebrain neuron development GO:0021884 13 5 0,000 6,175E-03 0,05801705 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,175E-03 0,05779476 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,175E-03 0,05757417 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,175E-03 0,05735526 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,175E-03 0,057138 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,175E-03 0,05692239 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,175E-03 0,0567084 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,175E-03 0,056496 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,175E-03 0,0562852 ! lipid glycosylation GO:0030259 7 5 0,000 6,175E-03 0,05607596 ! nucleobase transport GO:0015851 6 5 0,000 6,175E-03 0,05586827 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,175E-03 0,05566212 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,175E-03 0,05545748 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,175E-03 0,05525433 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,175E-03 0,05505268 ! basic amino acid transport GO:0015802 12 5 0,000 6,175E-03 0,05485248 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,175E-03 0,05465374 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,175E-03 0,05445644 ! actin nucleation GO:0045010 11 5 0,000 6,175E-03 0,05426055 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,175E-03 0,05406607 ! depurination GO:0045007 5 5 0,000 6,175E-03 0,05387298 ! depyrimidination GO:0045008 10 5 0,000 6,175E-03 0,05368126 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,175E-03 0,0534909 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,175E-03 0,05330188 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,175E-03 0,0531142 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,175E-03 0,05292784 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,175E-03 0,05274277 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,175E-03 0,052559 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,175E-03 0,0523765 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,175E-03 0,05219527 ! activated T cell proliferation GO:0050798 16 5 0,000 6,175E-03 0,05201529 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,175E-03 0,05183654 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,175E-03 0,05165902 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,175E-03 0,05148271 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,175E-03 0,0513076 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,175E-03 0,05113367 ! response to arsenic GO:0046685 11 5 0,000 6,175E-03 0,05096092 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,175E-03 0,05078934 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,175E-03 0,0506189 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,175E-03 0,05044961 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,175E-03 0,05028144 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,175E-03 0,0501144 ! response to mercury ion GO:0046689 8 5 0,000 6,175E-03 0,04994845 ! response to cadmium ion GO:0046686 7 5 0,000 6,175E-03 0,04978361 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,175E-03 0,04961985 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,175E-03 0,04945716 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 6,175E-03 0,04929553 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,175E-03 0,04913496 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,175E-03 0,04897543 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,175E-03 0,04881694 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,175E-03 0,04865946 ! decidualization GO:0046697 11 5 0,000 6,175E-03 0,048503 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,175E-03 0,04834754 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,175E-03 0,04819308 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,175E-03 0,0480396 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,175E-03 0,04788709 ! embryonic cleavage GO:0040016 6 5 0,000 6,175E-03 0,04773555 ! peroxisome fission GO:0016559 5 5 0,000 6,175E-03 0,04758496 ! histone demethylation GO:0016577 13 5 0,000 6,175E-03 0,04743532 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,175E-03 0,04728662 ! mitotic recombination GO:0006312 9 5 0,000 6,175E-03 0,04713885 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,175E-03 0,046992 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,175E-03 0,04684607 ! metaphase plate congression GO:0051310 7 5 0,000 6,175E-03 0,04670103 ! regulation of sterol transport GO:0032371 7 5 0,000 6,175E-03 0,04655689 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,175E-03 0,04641364 ! enteric nervous system development GO:0048484 8 5 0,000 6,175E-03 0,04627127 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,175E-03 0,04612977 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,175E-03 0,04598913 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,175E-03 0,04584934 ! muscle cell proliferation GO:0033002 12 5 0,000 6,175E-03 0,0457104 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,175E-03 0,04557231 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,175E-03 0,04543504 ! B cell homeostasis GO:0001782 13 5 0,000 6,175E-03 0,0452986 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,175E-03 0,04516297 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,175E-03 0,04502816 ! metaphase GO:0051323 11 5 0,000 6,175E-03 0,04489415 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,175E-03 0,04476093 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,175E-03 0,0446285 ! cellular response to nutrient GO:0031670 8 5 0,000 6,175E-03 0,04449685 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,175E-03 0,04436598 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,175E-03 0,04423587 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,175E-03 0,04410653 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,175E-03 0,04397794 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,175E-03 0,0438501 ! response to redox state GO:0051775 6 5 0,000 6,175E-03 0,04372299 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,175E-03 0,04359663 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,175E-03 0,04347099 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,175E-03 0,04334607 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,175E-03 0,04322187 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,175E-03 0,04309838 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,175E-03 0,04297559 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,175E-03 0,0428535 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,175E-03 0,04273211 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,175E-03 0,04261139 ! striatum development GO:0021756 14 5 0,000 6,175E-03 0,04249136 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,175E-03 0,042372 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,175E-03 0,04225331 ! glial cell migration GO:0008347 10 5 0,000 6,175E-03 0,04213529 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,175E-03 0,04201792 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,175E-03 0,0419012 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,175E-03 0,04178513 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,175E-03 0,04166971 ! T cell activation during immune response GO:0002286 9 5 0,000 6,175E-03 0,04155491 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,175E-03 0,04144075 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,175E-03 0,04132721 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,175E-03 0,0412143 ! neuroprotection GO:0043526 8 5 0,000 6,175E-03 0,041102 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,175E-03 0,04099031 ! regulation of sensory perception GO:0051931 8 5 0,000 6,175E-03 0,04087922 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,175E-03 0,04076874 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,175E-03 0,04065885 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,175E-03 0,04054955 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,175E-03 0,04044084 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,175E-03 0,04033271 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,175E-03 0,04022516 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,175E-03 0,04011817 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,175E-03 0,04001176 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,175E-03 0,03990591 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,175E-03 0,03980062 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,175E-03 0,03969588 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,175E-03 0,03959169 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,175E-03 0,03948805 ! protein palmitoylation GO:0018345 12 5 0,000 6,175E-03 0,03938494 ! drug metabolic process GO:0017144 7 5 0,000 6,175E-03 0,03928238 ! stem cell division GO:0017145 11 5 0,000 6,175E-03 0,03918035 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,175E-03 0,03907884 ! organ regeneration GO:0031100 7 5 0,000 6,175E-03 0,03897786 ! carnitine metabolic process GO:0009437 8 5 0,000 6,175E-03 0,03887741 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,175E-03 0,03877746 ! response to protein stimulus GO:0051789 158 96 1,000 6,343E-03 0,03973452 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 6,472E-03 0,04043562 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,405E-03 0,04614892 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,405E-03 0,0460315 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,405E-03 0,04591467 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,405E-03 0,04579843 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,405E-03 0,04568277 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,405E-03 0,0455677 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,405E-03 0,04545321 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,405E-03 0,04533929 ! response to oxygen radical GO:0000305 11 6 0,000 7,405E-03 0,04522595 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,405E-03 0,04511316 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,405E-03 0,04500094 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,405E-03 0,04488928 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,405E-03 0,04477816 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,405E-03 0,0446676 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,405E-03 0,04455758 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,405E-03 0,0444481 ! forebrain regionalization GO:0021871 9 6 0,000 7,405E-03 0,04433916 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,405E-03 0,04423075 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,405E-03 0,04412287 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,405E-03 0,04401552 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,405E-03 0,04390869 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,405E-03 0,04380237 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,405E-03 0,04369657 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,405E-03 0,04359127 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,405E-03 0,04348649 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,405E-03 0,0433822 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,405E-03 0,04327842 ! malate metabolic process GO:0006108 13 6 0,000 7,405E-03 0,04317513 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,405E-03 0,04307233 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,405E-03 0,04297002 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,405E-03 0,0428682 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,405E-03 0,04276685 ! protein refolding GO:0042026 15 6 0,000 7,405E-03 0,04266599 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,405E-03 0,0425656 ! opsonization GO:0008228 8 6 0,000 7,405E-03 0,04246568 ! mating behavior GO:0007617 7 6 0,000 7,405E-03 0,04236623 ! erythrocyte maturation GO:0043249 8 6 0,000 7,405E-03 0,04226724 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,405E-03 0,04216871 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,405E-03 0,04207065 GO:0006482|protein amino acid demethylation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,405E-03 0,04197304 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,405E-03 0,04187588 ! response to interferon-gamma GO:0034341 16 6 0,000 7,405E-03 0,04177916 ! toxin metabolic process GO:0009404 11 6 0,000 7,405E-03 0,0416829 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,405E-03 0,04158708 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,405E-03 0,04149169 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,405E-03 0,04139675 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 7,405E-03 0,04130223 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 7,405E-03 0,04120815 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,405E-03 0,0411145 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,405E-03 0,04102127 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,405E-03 0,04092846 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,405E-03 0,04083607 ! thymic T cell selection GO:0045061 16 6 0,000 7,405E-03 0,0407441 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,405E-03 0,04065254 ! protein lipoylation GO:0009249 10 6 0,000 7,405E-03 0,04056139 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,405E-03 0,04047065 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,405E-03 0,04038031 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,405E-03 0,04029038 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,405E-03 0,04020084 ! glutamate catabolic process GO:0006538 12 6 0,000 7,405E-03 0,0401117 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 7,405E-03 0,04002296 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,405E-03 0,03993461 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,405E-03 0,03984665 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,405E-03 0,03975907 ! hyperosmotic response GO:0006972 10 6 0,000 7,405E-03 0,03967188 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,405E-03 0,03958507 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,405E-03 0,03949864 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,405E-03 0,03941259 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,405E-03 0,03932691 ! urea metabolic process GO:0019627 7 6 0,000 7,405E-03 0,0392416 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,405E-03 0,03915666 ! neutrophil activation GO:0042119 7 6 0,000 7,405E-03 0,03907209 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,405E-03 0,03898788 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,405E-03 0,03890404 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,405E-03 0,03882055 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,405E-03 0,03873743 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,405E-03 0,03865465 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,405E-03 0,03857224 ! neuron apoptosis GO:0051402 15 6 0,000 7,405E-03 0,03849017 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,405E-03 0,03840845 ! T cell mediated immunity GO:0002456 17 6 0,000 7,405E-03 0,03832707 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,405E-03 0,03824604 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 7,405E-03 0,03816536 ! carnitine transport GO:0015879 10 6 0,000 7,405E-03 0,03808501 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,405E-03 0,038005 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,405E-03 0,03792532 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,405E-03 0,03784598 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,405E-03 0,03776697 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,405E-03 0,03768829 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,405E-03 0,03760993 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,405E-03 0,03753191 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,405E-03 0,0374542 ! establishment of spindle localization GO:0051293 16 6 0,000 7,405E-03 0,03737681 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,405E-03 0,03729975 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,405E-03 0,037223 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,405E-03 0,03714657 ! response to UV-C GO:0010225 14 6 0,000 7,405E-03 0,03707045 ! astrocyte development GO:0014002 16 6 0,000 7,405E-03 0,03699464 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,405E-03 0,03691914 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,405E-03 0,03684395 ! interaction with symbiont GO:0051702 14 6 0,000 7,405E-03 0,03676906 ! regulation of dendrite development GO:0050773 16 6 0,000 7,405E-03 0,03669448 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,405E-03 0,0366202 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,405E-03 0,03654622 ! response to copper ion GO:0046688 10 6 0,000 7,405E-03 0,03647254 ! response to exogenous dsRNA GO:0043330 13 6 0,000 7,405E-03 0,03639915 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,405E-03 0,03632606 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,405E-03 0,03625326 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,405E-03 0,03618076 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,405E-03 0,03610854 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,405E-03 0,03603661 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,405E-03 0,03596497 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,405E-03 0,03589361 ! hair follicle maturation GO:0048820 8 6 0,000 7,405E-03 0,03582253 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,405E-03 0,03575174 ! Schwann cell development GO:0014044 15 6 0,000 7,405E-03 0,03568122 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,405E-03 0,03561098 ! response to pheromone GO:0019236 6 6 0,000 7,405E-03 0,03554102 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,405E-03 0,03547133 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,405E-03 0,03540191 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,405E-03 0,03533277 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,405E-03 0,0352639 ! subpallium development GO:0021544 15 6 0,000 7,405E-03 0,03519529 ! neural tube patterning GO:0021532 8 6 0,000 7,405E-03 0,03512695 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,405E-03 0,03505887 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,405E-03 0,03499106 ! maintenance of organ identity GO:0048496 9 6 0,000 7,405E-03 0,03492351 ! G2 phase GO:0051319 16 6 0,000 7,405E-03 0,03485622 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,405E-03 0,03478919 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,405E-03 0,03472242 ! oxygen homeostasis GO:0032364 10 6 0,000 7,405E-03 0,0346559 ! establishment of planar polarity GO:0001736 7 6 0,000 7,405E-03 0,03458963 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,405E-03 0,03452362 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,405E-03 0,03445786 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,405E-03 0,03439235 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,405E-03 0,03432709 ! receptor internalization GO:0031623 11 6 0,000 7,405E-03 0,03426208 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 7,405E-03 0,03419731 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 7,405E-03 0,03413279 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,405E-03 0,03406851 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,405E-03 0,03400447 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,405E-03 0,03394067 ! protein deubiquitination GO:0016579 16 6 0,000 7,405E-03 0,03387711 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,405E-03 0,03381379 ! protein destabilization GO:0031648 9 6 0,000 7,405E-03 0,03375071 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,405E-03 0,03368786 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,405E-03 0,03362524 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,405E-03 0,03356285 ! regulation of viral transcription GO:0046782 11 6 0,000 7,405E-03 0,0335007 ! progesterone metabolic process GO:0042448 12 6 0,000 7,405E-03 0,03343878 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,405E-03 0,03337708 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,405E-03 0,03331561 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,405E-03 0,03325437 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,405E-03 0,03319335 ! determination of adult lifespan GO:0008340 17 6 0,000 7,405E-03 0,03313256 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,405E-03 0,03307199 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,405E-03 0,03301164 ! neural plate development GO:0001840 9 6 0,000 7,405E-03 0,03295151 ! catecholamine transport GO:0051937 9 6 0,000 7,405E-03 0,0328916 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,405E-03 0,0328319 ! sensory cilium assembly GO:0035058 10 6 0,000 7,405E-03 0,03277242 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,405E-03 0,03271316 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,405E-03 0,03265411 ! maternal placenta development GO:0001893 12 6 0,000 7,405E-03 0,03259528 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,405E-03 0,03253665 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,405E-03 0,03247824 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,405E-03 0,03242003 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,405E-03 0,03236204 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,405E-03 0,03230425 ! positive regulation of coagulation GO:0050820 13 6 0,000 7,405E-03 0,03224666 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,405E-03 0,03218929 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 8,634E-03 0,03746481 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 8,634E-03 0,03739838 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 8,634E-03 0,03733219 ! regulation of helicase activity GO:0051095 16 7 0,000 8,634E-03 0,03726623 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 8,634E-03 0,03720051 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 8,634E-03 0,03713501 ! sleep GO:0030431 16 7 0,000 8,634E-03 0,03706975 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 8,634E-03 0,03700471 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 8,634E-03 0,03693991 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 8,634E-03 0,03687533 ! prostate gland development GO:0030850 14 7 0,000 8,634E-03 0,03681097 ! nucleotide-sugar transport GO:0015780 11 7 0,000 8,634E-03 0,03674684 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,634E-03 0,03668293 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 8,634E-03 0,03661925 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 8,634E-03 0,03655578 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,634E-03 0,03649254 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 8,634E-03 0,03642951 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 8,634E-03 0,0363667 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 8,634E-03 0,03630411 ! SMAD protein complex assembly GO:0007183 13 7 0,000 8,634E-03 0,03624173 ! glycolipid transport GO:0046836 11 7 0,000 8,634E-03 0,03617957 ! protein amino acid sulfation GO:0006477 10 7 0,000 8,634E-03 0,03611761 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 8,634E-03 0,03605587 ! neuron adhesion GO:0007158 14 7 0,000 8,634E-03 0,03599435 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 8,634E-03 0,03593303 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 8,634E-03 0,03587192 ! establishment of tissue polarity GO:0007164 8 7 0,000 8,634E-03 0,03581101 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 8,634E-03 0,03575032 ! mRNA stabilization GO:0048255 18 7 0,000 8,634E-03 0,03568982 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 8,634E-03 0,03562954 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 8,634E-03 0,03556945 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 8,634E-03 0,03550957 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 8,634E-03 0,03544989 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 8,634E-03 0,03539041 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 8,634E-03 0,03533113 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 8,634E-03 0,03527205 ! lipoprotein transport GO:0042953 14 7 0,000 8,634E-03 0,03521317 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 8,634E-03 0,03515448 ! rhythmic behavior GO:0007622 17 7 0,000 8,634E-03 0,03509598 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 8,634E-03 0,03503769 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 8,634E-03 0,03497958 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 8,634E-03 0,03492167 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 8,634E-03 0,03486394 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 8,634E-03 0,03480641 ! regulation of odontogenesis GO:0042481 14 7 0,000 8,634E-03 0,03474907 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 8,634E-03 0,03469192 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 8,634E-03 0,03463495 ! mechanosensory behavior GO:0007638 16 7 0,000 8,634E-03 0,03457817 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 8,634E-03 0,03452158 ! positive regulation of isotype switching GO:0045830 17 7 0,000 8,634E-03 0,03446517 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 8,634E-03 0,03440895 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 8,634E-03 0,03435291 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,634E-03 0,03429705 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,634E-03 0,03424137 ! spinal cord patterning GO:0021511 14 7 0,000 8,634E-03 0,03418588 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 8,634E-03 0,03413056 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 8,634E-03 0,03407542 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 8,634E-03 0,03402046 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 8,634E-03 0,03396568 ! adrenal gland development GO:0030325 17 7 0,000 8,634E-03 0,03391107 ! cysteine metabolic process GO:0006534 13 7 0,000 8,634E-03 0,03385664 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 8,634E-03 0,03380238 ! ovulation GO:0030728 10 7 0,000 8,634E-03 0,0337483 ! adenohypophysis development GO:0021984 11 7 0,000 8,634E-03 0,03369439 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 8,634E-03 0,03364065 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 8,634E-03 0,03358708 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 8,634E-03 0,03353368 ! microtubule nucleation GO:0007020 21 7 0,000 8,634E-03 0,03348045 ! proline biosynthetic process GO:0006561 10 7 0,000 8,634E-03 0,0334274 ! tryptophan metabolic process GO:0006568 11 7 0,000 8,634E-03 0,0333745 ! thyroid hormone generation GO:0006590 13 7 0,000 8,634E-03 0,03332178 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 8,634E-03 0,03326922 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 8,634E-03 0,03321683 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,634E-03 0,0331646 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 8,634E-03 0,03311254 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 8,634E-03 0,03306064 ! galactose metabolic process GO:0006012 13 7 0,000 8,634E-03 0,0330089 ! vesicle fusion GO:0006906 20 7 0,000 8,634E-03 0,03295732 ! response to dietary excess GO:0002021 8 7 0,000 8,634E-03 0,03290591 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 8,634E-03 0,03285465 ! intracellular pH reduction GO:0051452 13 7 0,000 8,634E-03 0,03280356 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 8,634E-03 0,03275262 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 8,634E-03 0,03270184 ! organ growth GO:0035265 15 7 0,000 8,634E-03 0,03265122 ! nucleoside transport GO:0015858 11 7 0,000 8,634E-03 0,03260075 ! nucleoside salvage GO:0043174 11 7 0,000 8,634E-03 0,03255044 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 8,634E-03 0,03250029 ! male sex determination GO:0030238 15 7 0,000 8,634E-03 0,03245029 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 8,634E-03 0,03240044 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 8,634E-03 0,03235075 ! parturition GO:0007567 16 7 0,000 8,634E-03 0,0323012 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 8,634E-03 0,03225181 ! rRNA modification GO:0000154 14 7 0,000 8,634E-03 0,03220257 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 8,634E-03 0,03215349 ! spindle checkpoint GO:0031577 16 7 0,000 8,634E-03 0,03210455 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 8,634E-03 0,03205575 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 8,634E-03 0,03200711 ! monocyte differentiation GO:0030224 16 7 0,000 8,634E-03 0,03195862 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 8,634E-03 0,03191027 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 8,634E-03 0,03186206 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 8,634E-03 0,03181401 ! hyaluronan metabolic process GO:0030212 9 7 0,000 8,634E-03 0,03176609 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 8,634E-03 0,03171833 ! anterograde axon cargo transport GO:0008089 18 7 0,000 8,634E-03 0,0316707 ! fibrinolysis GO:0042730 11 7 0,000 8,634E-03 0,03162322 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 8,634E-03 0,03157588 ! skeletal muscle contraction GO:0003009 8 7 0,000 8,634E-03 0,03152868 ! eating behavior GO:0042755 8 7 0,000 8,634E-03 0,03148162 ! B cell lineage commitment GO:0002326 21 7 0,000 8,634E-03 0,0314347 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 8,634E-03 0,03138793 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 8,634E-03 0,03134129 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 8,634E-03 0,03129479 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 8,634E-03 0,03124842 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 8,634E-03 0,0312022 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 8,634E-03 0,03115611 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 8,634E-03 0,03111016 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 8,634E-03 0,03106434 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 8,634E-03 0,03101866 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 8,634E-03 0,03097311 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 8,634E-03 0,03092769 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 8,634E-03 0,03088241 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 8,634E-03 0,03083726 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 8,634E-03 0,03079224 ! histone ubiquitination GO:0016574 9 7 0,000 8,634E-03 0,03074736 ! regulation of meiosis GO:0040020 12 7 0,000 8,634E-03 0,0307026 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 8,634E-03 0,03065797 ! T cell lineage commitment GO:0002360 16 7 0,000 8,634E-03 0,03061348 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 8,634E-03 0,03056911 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 8,634E-03 0,03052487 ! membrane to membrane docking GO:0022614 14 7 0,000 8,634E-03 0,03048076 ! transcription termination GO:0006353 14 7 0,000 8,634E-03 0,03043678 ! coenzyme A metabolic process GO:0015936 12 7 0,000 8,634E-03 0,03039292 ! anaphase GO:0051322 18 7 0,000 8,634E-03 0,03034919 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 8,634E-03 0,03030558 ! axonal fasciculation GO:0007413 19 7 0,000 8,634E-03 0,0302621 ! negative regulation of nuclear division GO:0051784 15 7 0,000 8,634E-03 0,03021875 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 8,634E-03 0,03017552 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 8,634E-03 0,03013241 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 8,634E-03 0,03008942 ! diuresis GO:0030146 12 7 0,000 8,634E-03 0,03004656 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 8,634E-03 0,03000382 ! thiamin metabolic process GO:0006772 7 7 0,000 8,634E-03 0,0299612 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,634E-03 0,0299187 ! antibiotic transport GO:0042891 9 7 0,000 8,634E-03 0,02987633 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 8,634E-03 0,02983407 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 8,634E-03 0,02979193 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 8,634E-03 0,02974991 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 8,634E-03 0,02970801 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 8,634E-03 0,02966623 ! melanin biosynthetic process GO:0042438 10 7 0,000 8,634E-03 0,02962456 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 8,634E-03 0,02958301 ! dopamine biosynthetic process GO:0042416 18 7 0,000 8,634E-03 0,02954158 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 8,634E-03 0,02950026 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 8,634E-03 0,02945906 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 8,634E-03 0,02941797 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 8,634E-03 0,029377 ! endosome to lysosome transport GO:0008333 12 7 0,000 8,634E-03 0,02933614 ! protein modification by small protein removal GO:0070646 19 7 0,000 8,634E-03 0,0292954 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 8,634E-03 0,02925477 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 8,634E-03 0,02921425 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 8,634E-03 0,02917384 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 8,634E-03 0,02913354 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 8,634E-03 0,02909336 ! muscle adaptation GO:0043500 13 7 0,000 8,634E-03 0,02905329 ! embryonic heart tube development GO:0035050 14 7 0,000 8,634E-03 0,02901332 ! retina homeostasis GO:0001895 12 7 0,000 8,634E-03 0,02897347 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 8,634E-03 0,02893373 ! protein amino acid prenylation GO:0018346 19 7 0,000 8,634E-03 0,02889409 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 8,634E-03 0,02885456 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 8,634E-03 0,02881515 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 9,861E-03 0,0328668 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 9,861E-03 0,03282202 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 9,861E-03 0,03277736 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 9,861E-03 0,03273283 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 9,861E-03 0,03268841 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 9,861E-03 0,03264412 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 9,861E-03 0,03259995 ! male meiosis GO:0007140 9 8 0,000 9,861E-03 0,03255589 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 9,861E-03 0,03251196 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 9,861E-03 0,03246814 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 9,861E-03 0,03242444 ! meiotic prophase I GO:0007128 14 8 0,000 9,861E-03 0,03238086 ! response to zinc ion GO:0010043 12 8 0,000 9,861E-03 0,0323374 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 9,861E-03 0,03229405 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 9,861E-03 0,03225082 ! oligopeptide transport GO:0006857 16 8 0,000 9,861E-03 0,0322077 ! actin-myosin filament sliding GO:0033275 13 8 0,000 9,861E-03 0,0321647 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 9,861E-03 0,03212182 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 9,861E-03 0,03207904 ! signal peptide processing GO:0006465 12 8 0,000 9,861E-03 0,03203639 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 9,861E-03 0,03199384 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 9,861E-03 0,03195141 ! macrophage chemotaxis GO:0048246 12 8 0,000 9,861E-03 0,03190909 ! succinate metabolic process GO:0006105 17 8 0,000 9,861E-03 0,03186688 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 9,861E-03 0,03182478 ! membrane hyperpolarization GO:0060081 11 8 0,000 9,861E-03 0,0317828 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 9,861E-03 0,03174092 ! estrogen metabolic process GO:0008210 17 8 0,000 9,861E-03 0,03169916 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 9,861E-03 0,03165751 ! T-helper 1 type immune response GO:0042088 12 8 0,000 9,861E-03 0,03161596 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 9,861E-03 0,03157452 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 9,861E-03 0,0315332 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,861E-03 0,03149198 ! reflex GO:0060004 17 8 0,000 9,861E-03 0,03145086 ! endothelial cell differentiation GO:0045446 17 8 0,000 9,861E-03 0,03140986 ! glycerolipid catabolic process GO:0046503 14 8 0,000 9,861E-03 0,03136896 ! hemoglobin metabolic process GO:0020027 14 8 0,000 9,861E-03 0,03132817 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 9,861E-03 0,03128748 ! pigment granule organization GO:0048753 17 8 0,000 9,861E-03 0,0312469 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 9,861E-03 0,03120643 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 9,861E-03 0,03116606 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 9,861E-03 0,03112579 ! astrocyte differentiation GO:0048708 19 8 0,000 9,861E-03 0,03108563 ! histidine catabolic process GO:0006548 10 8 0,000 9,861E-03 0,03104557 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 9,861E-03 0,03100561 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 9,861E-03 0,03096576 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 9,861E-03 0,03092601 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 9,861E-03 0,03088636 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 9,861E-03 0,03084681 ! regulation of pigmentation during development GO:0048070 25 8 0,000 9,861E-03 0,03080737 ! melanin metabolic process GO:0006582 17 8 0,000 9,861E-03 0,03076802 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 9,861E-03 0,03072878 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 9,861E-03 0,03068963 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 9,861E-03 0,03065059 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 9,861E-03 0,03061164 ! macrophage activation GO:0042116 13 8 0,000 9,861E-03 0,03057279 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 9,861E-03 0,03053405 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 9,861E-03 0,03049539 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 9,861E-03 0,03045684 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 9,861E-03 0,03041839 ! purine salvage GO:0043101 12 8 0,000 9,861E-03 0,03038003 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 9,861E-03 0,03034177 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,861E-03 0,0303036 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 9,861E-03 0,03026553 ! osteoblast development GO:0002076 17 8 0,000 9,861E-03 0,03022756 ! positive regulation of vasodilation GO:0045909 14 8 0,000 9,861E-03 0,03018968 ! negative regulation of translational initiation GO:0045947 12 8 0,000 9,861E-03 0,03015189 ! Schwann cell differentiation GO:0014037 21 8 0,000 9,861E-03 0,0301142 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 9,861E-03 0,03007661 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 9,861E-03 0,0300391 ! response to UV-B GO:0010224 17 8 0,000 9,861E-03 0,0300017 ! protein targeting to vacuole GO:0006623 14 8 0,000 9,861E-03 0,02996438 ! protein retention in ER lumen GO:0006621 14 8 0,000 9,861E-03 0,02992716 ! intermediate filament organization GO:0045109 12 8 0,000 9,861E-03 0,02989003 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 9,861E-03 0,02985299 ! cellular extravasation GO:0045123 13 8 0,000 9,861E-03 0,02981604 ! cardiac muscle cell development GO:0055013 14 8 0,000 9,861E-03 0,02977919 ! response to antibiotic GO:0046677 11 8 0,000 9,861E-03 0,02974242 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 9,861E-03 0,02970575 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 9,861E-03 0,02966916 ! DNA topological change GO:0006265 12 8 0,000 9,861E-03 0,02963267 ! response to tropane GO:0014073 15 8 0,000 9,861E-03 0,02959627 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 9,861E-03 0,02955995 ! melanosome transport GO:0032402 13 8 0,000 9,861E-03 0,02952373 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 9,861E-03 0,02948759 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 9,861E-03 0,02945154 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 9,861E-03 0,02941558 ! mast cell activation GO:0045576 14 8 0,000 9,861E-03 0,02937971 ! multicellular organismal aging GO:0010259 20 8 0,000 9,861E-03 0,02934392 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 9,861E-03 0,02930823 ! gas homeostasis GO:0033483 14 8 0,000 9,861E-03 0,02927261 ! dendrite morphogenesis GO:0048813 14 8 0,000 9,861E-03 0,02923709 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 9,861E-03 0,02920165 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 9,861E-03 0,0291663 ! nucleosome disassembly GO:0006337 14 8 0,000 9,861E-03 0,02913103 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 9,861E-03 0,02909585 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 9,861E-03 0,02906075 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 9,861E-03 0,02902574 ! establishment of chromosome localization GO:0051303 14 8 0,000 9,861E-03 0,02899081 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 9,861E-03 0,02895596 ! intracellular lipid transport GO:0032365 16 8 0,000 9,861E-03 0,0289212 ! response to tumor cell GO:0002347 16 8 0,000 9,861E-03 0,02888652 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 9,861E-03 0,02885193 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 9,861E-03 0,02881742 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 9,861E-03 0,02878299 ! positive regulation of epidermis development GO:0045684 13 8 0,000 9,861E-03 0,02874864 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 9,861E-03 0,02871438 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 9,861E-03 0,02868019 ! hormone catabolic process GO:0042447 17 8 0,000 9,861E-03 0,02864609 ! glycolipid catabolic process GO:0019377 16 8 0,000 9,861E-03 0,02861207 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 9,861E-03 0,02857813 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 9,861E-03 0,02854427 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 9,861E-03 0,02851049 ! positive regulation of glucose import GO:0046326 8 8 0,000 9,861E-03 0,02847679 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 9,861E-03 0,02844317 ! adult feeding behavior GO:0008343 10 8 0,000 9,861E-03 0,02840962 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 9,861E-03 0,02837616 ! ATP catabolic process GO:0006200 11 8 0,000 9,861E-03 0,02834278 ! blastocyst growth GO:0001832 19 8 0,000 9,861E-03 0,02830947 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 9,861E-03 0,02827625 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 9,861E-03 0,0282431 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 9,861E-03 0,02821003 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 9,861E-03 0,02817703 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 9,861E-03 0,02814411 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 9,861E-03 0,02811127 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 9,861E-03 0,02807851 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 9,861E-03 0,02804582 ! amino sugar catabolic process GO:0046348 11 8 0,000 9,861E-03 0,02801321 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 9,861E-03 0,02798068 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 9,861E-03 0,02794822 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 9,861E-03 0,02791583 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 9,861E-03 0,02788352 ! behavioral response to nicotine GO:0035095 12 8 0,000 9,861E-03 0,02785129 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 9,861E-03 0,02781912 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 9,861E-03 0,02778704 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 9,861E-03 0,02775502 ! NAD biosynthetic process GO:0009435 17 8 0,000 9,861E-03 0,02772309 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 9,861E-03 0,02769122 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 9,861E-03 0,02765943 ! axon extension GO:0048675 16 9 0,000 0,01108736 0,03106239 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01108736 0,03102681 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01108736 0,03099131 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01108736 0,0309559 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01108736 0,03092056 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01108736 0,0308853 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01108736 0,03085012 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01108736 0,03081503 ! reproductive behavior GO:0019098 22 9 0,000 0,01108736 0,03078001 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01108736 0,03074507 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01108736 0,03071021 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01108736 0,03067543 ! UTP metabolic process GO:0046051 10 9 0,000 0,01108736 0,03064073 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01108736 0,03060611 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01108736 0,03057157 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01108736 0,0305371 ! artery development GO:0060840 25 9 0,000 0,01108736 0,03050271 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01108736 0,0304684 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01108736 0,03043417 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01108736 0,03040001 ! equilibrioception GO:0050957 20 9 0,000 0,01108736 0,03036593 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01108736 0,03033192 ! chemosensory behavior GO:0007635 21 9 0,000 0,01108736 0,030298 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01108736 0,03026414 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01108736 0,03023037 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01108736 0,03019666 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01108736 0,03016304 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01108736 0,03012949 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01108736 0,03009601 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01108736 0,03006261 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01108736 0,03002928 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01108736 0,02999602 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01108736 0,02996284 ! protein targeting to ER GO:0045047 25 9 0,000 0,01108736 0,02992973 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01108736 0,0298967 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01108736 0,02986374 ! T cell selection GO:0045058 27 9 0,000 0,01108736 0,02983085 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01108736 0,02979803 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01108736 0,02976528 ! glycine catabolic process GO:0006546 15 9 0,000 0,01108736 0,02973261 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01108736 0,02970001 ! endosome organization GO:0007032 20 9 0,000 0,01108736 0,02966748 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01108736 0,02963502 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01108736 0,02960263 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01108736 0,02957031 ! mannose metabolic process GO:0006013 13 9 0,000 0,01108736 0,02953807 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01108736 0,02950589 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01108736 0,02947378 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01108736 0,02944175 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01108736 0,02940978 ! receptor clustering GO:0043113 20 9 0,000 0,01108736 0,02937788 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01108736 0,02934605 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01108736 0,02931429 ! retinol metabolic process GO:0042572 20 9 0,000 0,01108736 0,0292826 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01108736 0,02925098 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01108736 0,02921943 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01108736 0,02918794 ! macrophage differentiation GO:0030225 15 9 0,000 0,01108736 0,02915652 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01108736 0,02912517 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01108736 0,02909389 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01108736 0,02906267 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01108736 0,02903152 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01108736 0,02900044 ! response to amine stimulus GO:0014075 13 9 0,000 0,01108736 0,02896942 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01108736 0,02893847 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01108736 0,02890759 ! erythrocyte development GO:0048821 17 9 0,000 0,01108736 0,02887677 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01108736 0,02884602 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01108736 0,02881533 ! renal water homeostasis GO:0003091 15 9 0,000 0,01108736 0,02878471 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01108736 0,02875415 ! icosanoid secretion GO:0032309 15 9 0,000 0,01108736 0,02872366 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01108736 0,02869323 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01108736 0,02866287 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01108736 0,02863257 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01108736 0,02860233 ! sterol catabolic process GO:0016127 14 9 0,000 0,01108736 0,02857216 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01108736 0,02854205 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01108736 0,02851201 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01108736 0,02848203 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01108736 0,02845211 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01108736 0,02842225 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01108736 0,02839246 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01108736 0,02836273 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01108736 0,02833306 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01108736 0,02830346 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01108736 0,02827391 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01108736 0,02824443 ! purine base metabolic process GO:0006144 25 9 0,000 0,01108736 0,02821501 ! pigment granule transport GO:0051904 17 9 0,000 0,01108736 0,02818565 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01108736 0,02815635 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01108736 0,02812711 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01108736 0,02809793 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01108736 0,02806882 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01108736 0,02803976 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01108736 0,02801076 ! mitochondrion localization GO:0051646 18 9 0,000 0,01108736 0,02798183 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01231184 0,03104007 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01231184 0,03100807 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01231184 0,03097614 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01231184 0,03094427 ! associative learning GO:0008306 21 10 0,000 0,01231184 0,03091247 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01231184 0,03088073 ! phosphate transport GO:0006817 24 10 0,000 0,01231184 0,03084906 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01231184 0,03081745 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01231184 0,03078591 ! CTP metabolic process GO:0046036 11 10 0,000 0,01231184 0,03075443 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01231184 0,03072301 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01231184 0,03069166 ! GTP metabolic process GO:0046039 11 10 0,000 0,01231184 0,03066038 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01231184 0,03062916 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01231184 0,030598 ! social behavior GO:0035176 29 10 0,000 0,01231184 0,0305669 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01231184 0,03053587 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01231184 0,0305049 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01231184 0,03047399 ! androgen metabolic process GO:0008209 17 10 0,000 0,01231184 0,03044315 ! phospholipid efflux GO:0033700 19 10 0,000 0,01231184 0,03041237 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01231184 0,03038165 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01231184 0,03035099 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01231184 0,03032039 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01231184 0,03028986 ! lung alveolus development GO:0048286 26 10 0,000 0,01231184 0,03025939 ! pathogenesis GO:0009405 17 10 0,000 0,01231184 0,03022898 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01231184 0,03019863 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01231184 0,03016834 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01231184 0,03013811 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01231184 0,03010794 ! endoderm development GO:0007492 18 10 0,000 0,01231184 0,03007783 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01231184 0,03004778 ! arginine catabolic process GO:0006527 17 10 0,000 0,01231184 0,0300178 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01231184 0,02998787 ! proline metabolic process GO:0006560 13 10 0,000 0,01231184 0,029958 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01231184 0,02992819 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01231184 0,02989844 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01231184 0,02986875 ! V(D)J recombination GO:0033151 34 10 0,000 0,01231184 0,02983912 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01231184 0,02980954 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01231184 0,02978003 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01231184 0,02975057 ! B cell proliferation GO:0042100 19 10 0,000 0,01231184 0,02972118 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01231184 0,02969184 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01231184 0,02966256 ! multicellular organism growth GO:0035264 19 10 0,000 0,01231184 0,02963333 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01231184 0,02960416 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01231184 0,02957505 ! ruffle organization GO:0031529 17 10 0,000 0,01231184 0,029546 ! epithelial cell development GO:0002064 21 10 0,000 0,01231184 0,02951701 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01231184 0,02948807 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01231184 0,02945919 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01231184 0,02943036 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01231184 0,02940159 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01231184 0,02937288 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01231184 0,02934423 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01231184 0,02931562 ! motor axon guidance GO:0008045 22 10 0,000 0,01231184 0,02928708 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01231184 0,02925859 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01231184 0,02923016 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01231184 0,02920178 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01231184 0,02917345 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01231184 0,02914518 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01231184 0,02911697 ! segment specification GO:0007379 15 10 0,000 0,01231184 0,02908881 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01231184 0,02906071 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01231184 0,02903266 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01231184 0,02900466 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01231184 0,02897672 ! response to dsRNA GO:0043331 23 10 0,000 0,01231184 0,02894883 ! DNA ligation GO:0006266 18 10 0,000 0,01231184 0,02892099 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01231184 0,02889321 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01231184 0,02886548 ! melanosome localization GO:0032400 16 10 0,000 0,01231184 0,02883781 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01231184 0,02881018 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01231184 0,02878261 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01231184 0,0287551 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01231184 0,02872763 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01231184 0,02870022 ! induction of an organ GO:0001759 17 10 0,000 0,01231184 0,02867286 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01231184 0,02864555 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01231184 0,0286183 ! protein sumoylation GO:0016925 17 10 0,000 0,01231184 0,02859109 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01231184 0,02856394 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01231184 0,02853684 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01231184 0,02850979 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01231184 0,02848279 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01231184 0,02845585 ! salivary gland development GO:0007431 28 10 0,000 0,01231184 0,02842895 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01231184 0,02840211 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01231184 0,02837531 ! midbrain development GO:0030901 14 10 0,000 0,01231184 0,02834857 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01231184 0,02832187 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01231184 0,02829523 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01231184 0,02826864 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01231184 0,02824209 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01231184 0,0282156 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01231184 0,02818916 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01231184 0,02816276 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01231184 0,02813642 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01231184 0,02811012 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01231184 0,02808388 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01231184 0,02805768 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01231184 0,02803153 ! blastocyst formation GO:0001825 18 10 0,000 0,01231184 0,02800543 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01231184 0,02797938 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01231184 0,02795337 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01231184 0,02792742 ! response to nicotine GO:0035094 20 10 0,000 0,01231184 0,02790151 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01231184 0,02787565 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01231184 0,02784984 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01353485 0,03058801 ! respiratory burst GO:0045730 17 11 0,000 0,01353485 0,03055974 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01353485 0,03053152 ! neuron fate specification GO:0048665 18 11 0,000 0,01353485 0,03050335 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01353485 0,03047524 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01353485 0,03044718 ! thyroid gland development GO:0030878 26 11 0,000 0,01353485 0,03041917 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01353485 0,03039121 ! synapsis GO:0007129 14 11 0,000 0,01353485 0,0303633 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01353485 0,03033544 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01353485 0,03030764 ! response to pain GO:0048265 27 11 0,000 0,01353485 0,03027988 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01353485 0,03025218 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01353485 0,03022453 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01353485 0,03019693 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01353485 0,03016937 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01353485 0,03014187 ! bone resorption GO:0045453 16 11 0,000 0,01353485 0,03011442 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01353485 0,03008702 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01353485 0,03005967 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01353485 0,03003236 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01353485 0,03000511 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01353485 0,02997791 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01353485 0,02995075 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01353485 0,02992365 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01353485 0,02989659 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01353485 0,02986959 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01353485 0,02984263 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01353485 0,02981572 ! UV protection GO:0009650 20 11 0,000 0,01353485 0,02978886 ! adult heart development GO:0007512 16 11 0,000 0,01353485 0,02976205 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01353485 0,02973528 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01353485 0,02970857 ! macroautophagy GO:0016236 19 11 0,000 0,01353485 0,0296819 ! temperature homeostasis GO:0001659 18 11 0,000 0,01353485 0,02965528 ! behavioral fear response GO:0001662 27 11 0,000 0,01353485 0,0296287 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01353485 0,02960218 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01353485 0,0295757 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01353485 0,02954927 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01353485 0,02952289 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01353485 0,02949655 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01353485 0,02947026 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01353485 0,02944402 ! regulation of organ growth GO:0046620 14 11 0,000 0,01353485 0,02941782 ! pigment granule localization GO:0051875 20 11 0,000 0,01353485 0,02939167 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01353485 0,02936557 ! vasoconstriction GO:0042310 20 11 0,000 0,01353485 0,02933952 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01353485 0,0293135 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01353485 0,02928754 ! embryonic axis specification GO:0000578 19 11 0,000 0,01353485 0,02926162 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01353485 0,02923575 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01353485 0,02920992 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01353485 0,02918414 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01353485 0,02915841 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01353485 0,02913272 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01353485 0,02910707 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01353485 0,02908147 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01353485 0,02905592 ! prophase GO:0051324 17 11 0,000 0,01353485 0,02903041 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01353485 0,02900494 ! nucleosome positioning GO:0016584 15 11 0,000 0,01353485 0,02897952 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01353485 0,02895414 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01353485 0,02892881 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01353485 0,02890353 ! apical protein localization GO:0045176 18 11 0,000 0,01353485 0,02887828 ! acid secretion GO:0046717 20 11 0,000 0,01353485 0,02885308 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01353485 0,02882793 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01353485 0,02880282 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01353485 0,02877775 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01353485 0,02875272 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01353485 0,02872774 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01353485 0,02870281 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01353485 0,02867791 ! cholesterol efflux GO:0033344 21 11 0,000 0,01353485 0,02865306 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01353485 0,02862825 ! oocyte development GO:0048599 20 11 0,000 0,01353485 0,02860349 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01353485 0,02857877 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01353485 0,02855409 ! embryonic gut development GO:0048566 19 11 0,000 0,01353485 0,02852945 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01353485 0,02850486 ! activation of innate immune response GO:0002218 16 11 0,000 0,01353485 0,0284803 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01353485 0,02845579 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01353485 0,02843133 ! lysogeny GO:0030069 22 11 0,000 0,01353485 0,0284069 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01353485 0,02838252 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01353485 0,02835818 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01353485 0,02833388 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01353485 0,02830962 ! nucleus localization GO:0051647 22 11 0,000 0,01353485 0,0282854 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01475637 0,03081181 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01475637 0,0307855 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01475637 0,03075923 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01475637 0,03073301 ! virus-host interaction GO:0019048 30 12 0,000 0,01475637 0,03070683 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01475637 0,0306807 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01475637 0,03065461 ! protein complex disassembly GO:0043241 28 12 0,000 0,01475637 0,03062856 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01475637 0,03060256 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01475637 0,03057661 ! hippocampus development GO:0021766 29 12 0,000 0,01475637 0,0305507 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01475637 0,03052483 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01475637 0,030499 ! T cell proliferation GO:0042098 32 12 0,000 0,01475637 0,03047322 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01475637 0,03044748 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01475637 0,03042179 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01475637 0,03039614 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01475637 0,03037053 ! drug transport GO:0015893 16 12 0,000 0,01475637 0,03034497 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01475637 0,03031945 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01475637 0,03029397 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01475637 0,03026853 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01475637 0,03024314 ! focal adhesion formation GO:0048041 37 12 0,000 0,01475637 0,03021779 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01475637 0,03019248 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01475637 0,03016721 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01475637 0,03014199 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01475637 0,03011681 ! lipid digestion GO:0044241 21 12 0,000 0,01475637 0,03009167 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01475637 0,03006657 ! entry into host cell GO:0030260 34 12 0,000 0,01475637 0,03004152 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01475637 0,0300165 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01475637 0,02999153 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01475637 0,0299666 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01475637 0,02994171 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01475637 0,02991686 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01475637 0,02989206 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01475637 0,02986729 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01475637 0,02984257 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01475637 0,02981788 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01475637 0,02979324 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01475637 0,02976864 ! cranial nerve development GO:0021545 23 12 0,000 0,01475637 0,02974408 ! fucose catabolic process GO:0019317 25 12 0,000 0,01475637 0,02971956 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01475637 0,02969507 ! histone acetylation GO:0016573 27 12 0,000 0,01475637 0,02967063 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01475637 0,02964623 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01475637 0,02962187 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01475637 0,02959755 ! zymogen activation GO:0031638 18 12 0,000 0,01475637 0,02957327 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01475637 0,02954903 ! T cell homeostasis GO:0043029 28 12 0,000 0,01475637 0,02952483 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01475637 0,02950067 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01475637 0,02947655 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01475637 0,02945247 ! oocyte differentiation GO:0009994 21 12 0,000 0,01475637 0,02942842 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01475637 0,02940442 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01475637 0,02938046 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01475637 0,02935653 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01475637 0,02933264 ! defense response to fungus GO:0050832 15 12 0,000 0,01475637 0,0293088 ! developmental induction GO:0031128 22 12 0,000 0,01475637 0,02928499 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01475637 0,02926122 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01475637 0,02923749 ! response to cold GO:0009409 17 12 0,000 0,01475637 0,02921379 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01475637 0,02919014 ! localization within membrane GO:0051668 26 12 0,000 0,01475637 0,02916652 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01597642 0,03155246 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01597642 0,03152698 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01597642 0,03150153 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01597642 0,03147613 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01597642 0,03145076 ! peroxisomal transport GO:0043574 28 13 0,000 0,01597642 0,03142544 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01597642 0,03140016 ! cartilage condensation GO:0001502 22 13 0,000 0,01597642 0,03137492 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01597642 0,03134972 ! organelle fusion GO:0048284 36 13 0,000 0,01597642 0,03132456 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01597642 0,03129944 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01597642 0,03127436 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01597642 0,03124932 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01597642 0,03122432 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01597642 0,03119936 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01597642 0,03117444 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01597642 0,03114956 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01597642 0,03112472 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01597642 0,03109992 ! methionine metabolic process GO:0006555 31 13 0,000 0,01597642 0,03107516 ! plasma membrane organization GO:0007009 27 13 0,000 0,01597642 0,03105043 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01597642 0,03102575 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01597642 0,03100111 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01597642 0,0309765 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01597642 0,03095194 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01597642 0,03092741 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01597642 0,03090293 ! exocrine system development GO:0035272 34 13 0,000 0,01597642 0,03087848 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01597642 0,03085407 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01597642 0,0308297 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01597642 0,03080536 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01597642 0,03078107 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01597642 0,03075681 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01597642 0,0307326 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01597642 0,03070842 ! protein homotetramerization GO:0051289 24 13 0,000 0,01597642 0,03068427 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01597642 0,03066017 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01597642 0,0306361 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01597642 0,03061208 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01597642 0,03058808 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01597642 0,03056413 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01597642 0,03054022 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01597642 0,03051634 ! histone methylation GO:0016571 29 13 0,000 0,01597642 0,0304925 ! chromatin silencing GO:0006342 29 13 0,000 0,01597642 0,03046869 ! gland morphogenesis GO:0022612 31 13 0,000 0,01597642 0,03044493 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01597642 0,0304212 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01597642 0,0303975 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01597642 0,03037385 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01597642 0,03035023 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01597642 0,03032665 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01597642 0,0303031 ! spleen development GO:0048536 24 13 0,000 0,01597642 0,03027959 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01597642 0,03025612 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01597642 0,03023268 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01597642 0,03020928 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01597642 0,03018592 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01597642 0,03016259 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01597642 0,0301393 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01597642 0,03011605 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01597642 0,03009283 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01597642 0,03006964 ! insulin secretion GO:0030073 24 13 0,000 0,01597642 0,03004649 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01597642 0,03002338 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01597642 0,0300003 ! acrosome reaction GO:0007340 19 13 0,000 0,01597642 0,02997726 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01597642 0,02995426 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01597642 0,02993129 ! rRNA transcription GO:0009303 28 14 0,000 0,01719499 0,03218955 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01719499 0,0321649 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01719499 0,03214029 ! water transport GO:0006833 21 14 0,000 0,01719499 0,03211572 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01719499 0,03209119 ! non-recombinational repair GO:0000726 29 14 0,000 0,01719499 0,03206669 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01719499 0,03204223 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01719499 0,03201781 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01719499 0,03199342 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01719499 0,03196907 ! lipid localization GO:0010876 32 14 0,000 0,01719499 0,03194476 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01719499 0,03192049 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01719499 0,03189625 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01719499 0,03187205 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01719499 0,03184789 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01719499 0,03182376 ! arginine metabolic process GO:0006525 21 14 0,000 0,01719499 0,03179967 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01719499 0,03177562 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01719499 0,0317516 ! regulation of heart rate GO:0002027 25 14 0,000 0,01719499 0,03172762 ! fear response GO:0042596 34 14 0,000 0,01719499 0,03170367 ! organic alcohol transport GO:0015850 29 14 0,000 0,01719499 0,03167976 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01719499 0,03165589 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01719499 0,03163205 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01719499 0,03160825 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01719499 0,03158448 ! bone mineralization GO:0030282 18 14 0,000 0,01719499 0,03156075 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01719499 0,03153706 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01719499 0,0315134 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01719499 0,03148978 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01719499 0,03146619 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01719499 0,03144264 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01719499 0,03141912 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01719499 0,03139564 ! ribosome assembly GO:0042255 18 14 0,000 0,01719499 0,03137219 ! cerebellum development GO:0021549 23 14 0,000 0,01719499 0,03134878 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01719499 0,0313254 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01719499 0,03130206 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01719499 0,03127875 ! response to gamma radiation GO:0010332 30 14 0,000 0,01719499 0,03125548 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01719499 0,03123224 ! NADP metabolic process GO:0006739 24 14 0,000 0,01719499 0,03120904 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01719499 0,03118587 ! oxygen transport GO:0015671 22 14 0,000 0,01719499 0,03116273 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01719499 0,03113963 ! male genitalia development GO:0030539 26 14 0,000 0,01719499 0,03111657 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01719499 0,03109353 ! regulation of axon extension GO:0030516 43 14 0,000 0,01719499 0,03107054 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01719499 0,03104757 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01719499 0,03102464 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01719499 0,03100174 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01841209 0,03317163 ! lactation GO:0007595 30 15 0,000 0,01841209 0,03314718 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01841209 0,03312278 ! reproductive cellular process GO:0048610 22 15 0,000 0,01841209 0,0330984 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01841209 0,03307407 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01841209 0,03304976 ! superoxide anion generation GO:0042554 22 15 0,000 0,01841209 0,0330255 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01841209 0,03300127 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01841209 0,03297707 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01841209 0,03295292 ! copper ion transport GO:0006825 22 15 0,000 0,01841209 0,03292879 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01841209 0,0329047 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01841209 0,03288065 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01841209 0,03285663 ! sulfate transport GO:0008272 27 15 0,000 0,01841209 0,03283265 ! response to cAMP GO:0051591 25 15 0,000 0,01841209 0,0328087 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01841209 0,03278479 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01841209 0,03276091 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01841209 0,03273707 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01841209 0,03271326 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01841209 0,03268948 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01841209 0,03266574 ! vesicle coating GO:0006901 38 15 0,000 0,01841209 0,03264204 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01841209 0,03261837 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01841209 0,03259473 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01841209 0,03257113 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01841209 0,03254756 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01841209 0,03252403 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01841209 0,03250053 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01841209 0,03247706 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01841209 0,03245363 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01841209 0,03243023 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01841209 0,03240687 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01841209 0,03238353 ! histone deacetylation GO:0016575 24 15 0,000 0,01841209 0,03236024 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01841209 0,03233697 ! water homeostasis GO:0030104 28 15 0,000 0,01841209 0,03231374 ! cofactor transport GO:0051181 30 15 0,000 0,01841209 0,03229055 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01841209 0,03226738 ! muscle maintenance GO:0046716 26 15 0,000 0,01841209 0,03224425 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01841209 0,03222115 ! intestinal absorption GO:0050892 31 15 0,000 0,01841209 0,03219809 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01841209 0,03217506 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01841209 0,03215206 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01841209 0,03212909 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01841209 0,03210616 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01841209 0,03208326 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01841209 0,03206039 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01841209 0,03203756 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01841209 0,03201475 ! actin filament polymerization GO:0030041 27 15 0,000 0,01841209 0,03199198 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01841209 0,03196925 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01962771 0,03405575 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01962771 0,03403158 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01962771 0,03400744 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01962771 0,03398334 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01962771 0,03395928 ! bone remodeling GO:0046849 28 16 0,000 0,01962771 0,03393524 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01962771 0,03391124 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01962771 0,03388728 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01962771 0,03386334 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01962771 0,03383945 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01962771 0,03381558 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01962771 0,03379175 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01962771 0,03376796 ! startle response GO:0001964 28 16 0,000 0,01962771 0,03374419 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01962771 0,03372046 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01962771 0,03369676 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01962771 0,0336731 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01962771 0,03364947 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01962771 0,03362587 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01962771 0,03360231 ! pituitary gland development GO:0021983 30 16 0,000 0,01962771 0,03357878 ! response to osmotic stress GO:0006970 27 16 0,000 0,01962771 0,03355528 ! lysosomal transport GO:0007041 31 16 0,000 0,01962771 0,03353182 ! L-amino acid transport GO:0015807 33 16 0,000 0,01962771 0,03350838 ! stem cell development GO:0048864 46 16 0,000 0,01962771 0,03348498 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01962771 0,03346162 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01962771 0,03343828 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01962771 0,03341498 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01962771 0,03339171 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01962771 0,03336847 ! axon cargo transport GO:0008088 46 16 0,000 0,01962771 0,03334527 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01962771 0,0333221 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,01962771 0,03329896 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01962771 0,03327585 ! DNA replication initiation GO:0006270 28 16 0,000 0,01962771 0,03325277 ! neuron recognition GO:0008038 40 16 0,000 0,01962771 0,03322973 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01962771 0,03320672 ! tissue regeneration GO:0042246 27 16 0,000 0,01962771 0,03318373 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01962771 0,03316079 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01962771 0,03313787 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01962771 0,03311498 ! biomineral formation GO:0031214 22 16 0,000 0,01962771 0,03309213 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01962771 0,03306931 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01962771 0,03304652 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01962771 0,03302376 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01962771 0,03300103 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01962771 0,03297833 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01962771 0,03295567 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01962771 0,03293303 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01962771 0,03291043 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01962771 0,03288786 ! peptide hormone processing GO:0016486 27 16 0,000 0,01962771 0,03286532 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02084186 0,03487443 ! metencephalon development GO:0022037 32 17 0,000 0,02084186 0,03485056 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02084186 0,03482672 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02084186 0,03480292 ! signal complex assembly GO:0007172 47 17 0,000 0,02084186 0,03477915 ! filopodium assembly GO:0046847 42 17 0,000 0,02084186 0,03475541 ! endothelial cell migration GO:0043542 31 17 0,000 0,02084186 0,0347317 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02084186 0,03470802 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02084186 0,03468438 ! glial cell development GO:0021782 28 17 0,000 0,02084186 0,03466077 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02084186 0,03463719 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02084186 0,03461364 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02084186 0,03459013 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02084186 0,03456665 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02084186 0,03454319 ! myoblast differentiation GO:0045445 50 17 0,000 0,02084186 0,03451978 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02084186 0,03449639 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02084186 0,03447303 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02084186 0,03444971 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02084186 0,03442642 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02084186 0,03440315 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02084186 0,03437993 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02084186 0,03435673 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02084186 0,03433356 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02084186 0,03431042 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02084186 0,03428732 ! regulation of protein binding GO:0043393 33 17 0,000 0,02084186 0,03426425 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02084186 0,0342412 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02084186 0,03421819 ! genitalia development GO:0048806 32 17 0,000 0,02084186 0,03419521 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02084186 0,03417226 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02084186 0,03414934 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02084186 0,03412645 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02084186 0,0341036 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02084186 0,03408077 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02084186 0,03405797 ! steroid catabolic process GO:0006706 34 17 0,000 0,02084186 0,03403521 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02084186 0,03401247 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02084186 0,03398977 ! gas transport GO:0015669 26 17 0,000 0,02084186 0,03396709 ! organic cation transport GO:0015695 32 17 0,000 0,02084186 0,03394445 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02084186 0,03392183 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02084186 0,03389925 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02084186 0,03387669 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02205454 0,03582397 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02205454 0,03580017 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02205454 0,0357764 ! limbic system development GO:0021761 40 18 0,000 0,02205454 0,03575266 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02205454 0,03572895 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02205454 0,03570527 ! adult walking behavior GO:0007628 36 18 0,000 0,02205454 0,03568162 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02205454 0,03565801 ! heart looping GO:0001947 34 18 0,000 0,02205454 0,03563443 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02205454 0,03561087 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02205454 0,03558735 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02205454 0,03556386 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02205454 0,0355404 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02205454 0,03551698 ! glycine metabolic process GO:0006544 30 18 0,000 0,02205454 0,03549358 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02205454 0,03547021 ! response to retinoic acid GO:0032526 31 18 0,000 0,02205454 0,03544688 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02205454 0,03542357 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02205454 0,0354003 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02205454 0,03537705 ! DNA integration GO:0015074 32 18 0,000 0,02205454 0,03535384 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02205454 0,03533066 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02205454 0,0353075 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02205454 0,03528438 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02205454 0,03526129 ! neural crest cell migration GO:0001755 41 18 0,000 0,02205454 0,03523823 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02205454 0,0352152 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02205454 0,0351922 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02205454 0,03516922 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02205454 0,03514628 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02205454 0,03512337 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02205454 0,03510049 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02205454 0,03507764 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02205454 0,03505482 ! detection of bacterium GO:0016045 22 18 0,000 0,02205454 0,03503202 ! nerve development GO:0021675 34 18 0,000 0,02205454 0,03500926 ! defense response to virus GO:0051607 43 18 0,000 0,02205454 0,03498653 ! microspike assembly GO:0030035 46 18 0,000 0,02205454 0,03496382 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02205454 0,03494115 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02205454 0,0349185 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02326576 0,03681234 ! positive regulation of translation GO:0045727 31 19 0,000 0,02326576 0,03678851 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02326576 0,03676471 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02326576 0,03674095 ! neuron maturation GO:0042551 46 19 0,000 0,02326576 0,03671721 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02326576 0,03669351 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02326576 0,03666984 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02326576 0,03664619 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02326576 0,03662258 ! inositol metabolic process GO:0006020 33 19 0,000 0,02326576 0,036599 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02326576 0,03657545 ! memory GO:0007613 34 19 0,000 0,02326576 0,03655193 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02326576 0,03652844 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02326576 0,03650498 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02326576 0,03648155 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02326576 0,03645815 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02326576 0,03643477 ! cerebral cortex development GO:0021987 40 19 0,000 0,02326576 0,03641143 ! pigmentation during development GO:0048066 42 19 0,000 0,02326576 0,03638812 ! response to vitamin A GO:0033189 32 19 0,000 0,02326576 0,03636484 ! heme metabolic process GO:0042168 40 19 0,000 0,02326576 0,03634159 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02326576 0,03631837 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02326576 0,03629518 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02326576 0,03627202 ! response to fungus GO:0009620 26 19 0,000 0,02326576 0,03624888 ! peptide cross-linking GO:0018149 39 19 0,000 0,02326576 0,03622578 ! protein export from nucleus GO:0006611 40 19 0,000 0,02326576 0,03620271 ! heart process GO:0003015 32 19 0,000 0,02326576 0,03617966 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02326576 0,03615665 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02326576 0,03613366 ! visual learning GO:0008542 38 19 0,000 0,02326576 0,0361107 ! cellular pigmentation GO:0033059 37 19 0,000 0,02326576 0,03608778 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02326576 0,03606488 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02326576 0,03604201 ! vitamin transport GO:0051180 31 19 0,000 0,02326576 0,03601917 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02326576 0,03599636 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02326576 0,03597357 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02326576 0,03595082 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02326576 0,0359281 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02326576 0,0359054 ! cilium assembly GO:0042384 38 19 0,000 0,02326576 0,03588273 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02326576 0,03586009 ! protein secretion GO:0009306 45 20 0,000 0,02447551 0,03770092 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02447551 0,03767717 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02447551 0,03765344 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02447551 0,03762974 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02447551 0,03760608 ! skin development GO:0043588 42 20 0,000 0,02447551 0,03758244 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02447551 0,03755883 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02447551 0,03753526 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02447551 0,03751171 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02447551 0,03748819 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02447551 0,0374647 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02447551 0,03744124 ! response to vitamin GO:0033273 36 20 0,000 0,02447551 0,03741781 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02447551 0,03739441 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02447551 0,03737104 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02447551 0,0373477 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02447551 0,03732438 ! response to alkaloid GO:0043279 38 20 0,000 0,02447551 0,0373011 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02447551 0,03727784 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02447551 0,03725462 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02447551 0,03723142 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02447551 0,03720825 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02447551 0,03718511 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02447551 0,037162 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02447551 0,03713892 ! body fluid secretion GO:0007589 33 20 0,000 0,02447551 0,03711587 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02447551 0,03709284 ! peptide secretion GO:0002790 38 20 0,000 0,02447551 0,03706985 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02447551 0,03704688 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02447551 0,03702394 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02447551 0,03700103 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02447551 0,03697815 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02447551 0,03695529 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02447551 0,03693247 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02447551 0,03690967 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02447551 0,0368869 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02447551 0,03686416 ! regulation of glucose import GO:0046324 30 20 0,000 0,02447551 0,03684144 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02447551 0,03681876 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02447551 0,0367961 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02447551 0,03677347 ! negative regulation of translation GO:0017148 32 20 0,000 0,02447551 0,03675087 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02447551 0,03672829 ! regulation of cell killing GO:0031341 46 21 0,000 0,02568379 0,0385178 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02568379 0,03849417 ! hormone secretion GO:0046879 39 21 0,000 0,02568379 0,03847057 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02568379 0,038447 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02568379 0,03842345 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02568379 0,03839994 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02568379 0,03837645 ! ovarian follicle development GO:0001541 39 21 0,000 0,02568379 0,038353 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02568379 0,03832957 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02568379 0,03830617 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02568379 0,03828279 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02568379 0,03825945 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02568379 0,03823614 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02568379 0,03821285 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02568379 0,03818959 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02568379 0,03816636 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02568379 0,03814316 ! sensory perception of pain GO:0019233 33 21 0,000 0,02568379 0,03811999 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02568379 0,03809684 ! diencephalon development GO:0021536 36 21 0,000 0,02568379 0,03807373 ! collagen fibril organization GO:0030199 62 21 0,000 0,02568379 0,03805064 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02568379 0,03802758 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02568379 0,03800454 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02568379 0,03798154 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02568379 0,03795856 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02568379 0,03793561 ! collagen catabolic process GO:0030574 29 21 0,000 0,02568379 0,03791269 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02568379 0,0378898 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02568379 0,03786693 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02568379 0,03784409 ! actin filament-based movement GO:0030048 47 21 0,000 0,02568379 0,03782128 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02568379 0,03779849 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02689061 0,03955073 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02689061 0,03952693 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02689061 0,03950317 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02689061 0,03947943 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02689061 0,03945571 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02689061 0,03943203 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02689061 0,03940838 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02689061 0,03938475 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02689061 0,03936115 ! cellular response to starvation GO:0009267 37 22 0,000 0,02689061 0,03933758 ! vacuolar transport GO:0007034 41 22 0,000 0,02689061 0,03931404 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02689061 0,03929053 ! fucose metabolic process GO:0006004 44 22 0,000 0,02689061 0,03926704 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02689061 0,03924359 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02689061 0,03922016 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02689061 0,03919676 ! ureteric bud development GO:0001657 50 22 0,000 0,02689061 0,03917338 ! cell aging GO:0007569 48 22 0,000 0,02689061 0,03915004 ! stem cell differentiation GO:0048863 57 22 0,000 0,02689061 0,03912672 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02689061 0,03910343 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02689061 0,03908017 ! cytolysis GO:0019835 27 22 0,000 0,02689061 0,03905694 ! renal system process GO:0003014 42 22 0,000 0,02689061 0,03903373 ! vasodilation GO:0042311 40 22 0,000 0,02689061 0,03901055 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02689061 0,0389874 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02689061 0,03896427 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02689061 0,03894118 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02689061 0,03891811 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02689061 0,03889507 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02689061 0,03887205 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02689061 0,03884906 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02689061 0,0388261 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02689061 0,03880317 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02689061 0,03878026 ! sarcomere organization GO:0045214 32 22 0,000 0,02689061 0,03875738 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02689061 0,03873453 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02689061 0,03871171 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02689061 0,03868891 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02689061 0,03866614 ! gut development GO:0048565 44 22 0,000 0,02689061 0,03864339 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02689061 0,03862067 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02689061 0,03859798 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02689061 0,03857532 ! protein stabilization GO:0050821 41 22 0,000 0,02689061 0,03855268 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02809597 0,04025716 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02809597 0,04023356 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02809597 0,04020999 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02809597 0,04018645 ! gluconeogenesis GO:0006094 38 23 0,000 0,02809597 0,04016294 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02809597 0,04013945 ! viral genome replication GO:0019079 44 23 0,000 0,02809597 0,04011599 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02809597 0,04009256 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02809597 0,04006915 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02809597 0,04004578 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02809597 0,04002243 ! regeneration GO:0031099 42 23 0,000 0,02809597 0,0399991 ! axis specification GO:0009798 43 23 0,000 0,02809597 0,03997581 ! visual behavior GO:0007632 46 23 0,000 0,02809597 0,03995254 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02809597 0,0399293 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02809597 0,03990608 ! response to ethanol GO:0045471 47 23 0,000 0,02809597 0,03988289 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02809597 0,03985973 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02809597 0,0398366 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02809597 0,03981349 ! peroxisome organization GO:0007031 43 23 0,000 0,02809597 0,03979041 ! lysosome organization GO:0007040 47 23 0,000 0,02809597 0,03976736 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02809597 0,03974433 ! vesicle targeting GO:0006903 49 23 0,000 0,02809597 0,03972133 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02809597 0,03969836 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02809597 0,03967541 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02809597 0,03965249 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02809597 0,0396296 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02809597 0,03960673 ! DNA modification GO:0006304 36 23 0,000 0,02809597 0,03958389 ! fatty acid transport GO:0015908 47 23 0,000 0,02809597 0,03956107 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02809597 0,03953828 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02809597 0,03951552 ! hormone transport GO:0009914 41 23 0,000 0,02809597 0,03949279 ! cell-cell recognition GO:0009988 28 23 0,000 0,02809597 0,03947008 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02809597 0,03944739 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02809597 0,03942473 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02809597 0,0394021 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,02929987 0,04106689 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,02929987 0,04104334 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,02929987 0,04101982 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,02929987 0,04099633 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,02929987 0,04097286 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,02929987 0,04094942 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,02929987 0,04092601 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,02929987 0,04090262 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,02929987 0,04087926 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,02929987 0,04085593 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,02929987 0,04083262 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,02929987 0,04080935 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,02929987 0,04078609 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,02929987 0,04076287 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,02929987 0,04073967 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,02929987 0,04071649 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,02929987 0,04069334 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,02929987 0,04067022 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,02929987 0,04064713 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,02929987 0,04062406 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,02929987 0,04060102 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,02929987 0,040578 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,02929987 0,04055501 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,02929987 0,04053204 ! membrane depolarization GO:0051899 45 24 0,000 0,02929987 0,04050911 ! pallium development GO:0021543 56 24 0,000 0,02929987 0,04048619 ! oogenesis GO:0048477 44 24 0,000 0,02929987 0,04046331 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,02929987 0,04044045 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,02929987 0,04041761 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,02929987 0,0403948 ! platelet activation GO:0030168 41 24 0,000 0,02929987 0,04037202 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,02929987 0,04034926 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,02929987 0,04032653 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,02929987 0,04030382 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,02929987 0,04028114 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,02929987 0,04025849 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,02929987 0,04023586 ! regulation of amine transport GO:0051952 41 24 0,000 0,02929987 0,04021325 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,02929987 0,04019067 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03050232 0,04181659 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03050232 0,04179314 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03050232 0,04176971 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03050232 0,04174631 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03050232 0,04172293 ! phototransduction GO:0007602 37 25 0,000 0,03050232 0,04169959 ! keratinization GO:0031424 37 25 0,000 0,03050232 0,04167626 ! vasculogenesis GO:0001570 49 25 0,000 0,03050232 0,04165297 ! vacuole organization GO:0007033 49 25 0,000 0,03050232 0,0416297 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03050232 0,04160646 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03050232 0,04158324 ! receptor metabolic process GO:0043112 53 25 0,000 0,03050232 0,04156005 ! chromosome condensation GO:0030261 48 25 0,000 0,03050232 0,04153688 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03050232 0,04151374 ! regulation of behavior GO:0050795 48 25 0,000 0,03050232 0,04149062 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03050232 0,04146754 ! interaction with host GO:0051701 66 25 0,000 0,03050232 0,04144447 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03050232 0,04142144 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03050232 0,04139842 ! immunoglobulin production GO:0002377 62 25 0,000 0,03050232 0,04137544 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03050232 0,04135248 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03050232 0,04132954 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03050232 0,04130663 ! liver development GO:0001889 55 25 0,000 0,03050232 0,04128375 ! protein tetramerization GO:0051262 57 25 0,000 0,03050232 0,04126089 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03170331 0,04286175 ! myelination GO:0042552 50 26 0,000 0,03170331 0,04283804 ! initiation of viral infection GO:0019059 60 26 0,000 0,03170331 0,04281436 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03170331 0,0427907 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03170331 0,04276708 ! molting cycle process GO:0022404 52 26 0,000 0,03170331 0,04274347 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03170331 0,0427199 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03170331 0,04269635 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03170331 0,04267282 ! spinal cord development GO:0021510 54 26 0,000 0,03170331 0,04264933 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03170331 0,04262585 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03170331 0,04260241 ! digestive system process GO:0022600 49 26 0,000 0,03170331 0,04257899 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03170331 0,04255559 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03170331 0,04253222 ! neural crest cell development GO:0014032 59 26 0,000 0,03170331 0,04250888 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03170331 0,04248556 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03170331 0,04246227 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03170331 0,042439 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03170331 0,04241576 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03170331 0,04239254 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03170331 0,04236935 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03170331 0,04234619 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03170331 0,04232305 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03170331 0,04229993 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03170331 0,04227684 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03170331 0,04225378 ! blastocyst development GO:0001824 50 26 0,000 0,03170331 0,04223074 ! telomere organization GO:0032200 46 26 0,000 0,03170331 0,04220773 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03170331 0,04218474 ! neural tube closure GO:0001843 58 26 0,000 0,03170331 0,04216177 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03170331 0,04213883 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03170331 0,04211592 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03290284 0,04368567 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03290284 0,04366194 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03290284 0,04363824 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03290284 0,04361456 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03290284 0,04359091 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03290284 0,04356728 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03290284 0,04354368 ! iron ion transport GO:0006826 65 27 0,000 0,03290284 0,04352011 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03290284 0,04349656 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03290284 0,04347303 ! tube lumen formation GO:0035148 59 27 0,000 0,03290284 0,04344953 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03290284 0,04342606 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03290284 0,04340261 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03290284 0,04337919 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03290284 0,04335579 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03290284 0,04333242 ! response to starvation GO:0042594 47 27 0,000 0,03290284 0,04330907 ! response to toxin GO:0009636 49 27 0,000 0,03290284 0,04328575 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03290284 0,04326245 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03290284 0,04323918 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03290284 0,04321593 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03290284 0,04319271 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03290284 0,04316952 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03290284 0,04314634 ! neuron fate commitment GO:0048663 52 28 0,000 0,03410092 0,04469343 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03410092 0,04466946 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03410092 0,04464553 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03410092 0,04462161 ! vesicle docking GO:0048278 55 28 0,000 0,03410092 0,04459773 ! circadian rhythm GO:0007623 56 28 0,000 0,03410092 0,04457386 ! dendrite development GO:0016358 67 28 0,000 0,03410092 0,04455003 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03410092 0,04452622 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03410092 0,04450243 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03410092 0,04447867 ! base-excision repair GO:0006284 41 28 0,000 0,03410092 0,04445494 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03410092 0,04443123 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03410092 0,04440754 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03410092 0,04438388 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03410092 0,04436025 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03410092 0,04433664 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03410092 0,04431306 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03410092 0,0442895 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03410092 0,04426597 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03410092 0,04424246 ! lipid oxidation GO:0034440 48 28 0,000 0,03410092 0,04421898 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03410092 0,04419552 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03410092 0,04417208 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03529755 0,04569789 ! translational initiation GO:0006413 66 29 0,000 0,03529755 0,04567369 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03529755 0,04564951 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03529755 0,04562536 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03529755 0,04560123 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03529755 0,04557713 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03529755 0,04555305 ! primary neural tube formation GO:0014020 61 29 0,000 0,03529755 0,045529 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03529755 0,04550497 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03529755 0,04548097 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03529755 0,045457 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03529755 0,04543305 ! somitogenesis GO:0001756 52 29 0,000 0,03529755 0,04540912 ! synaptogenesis GO:0007416 46 29 0,000 0,03529755 0,04538522 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03529755 0,04536135 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03529755 0,0453375 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03529755 0,04531367 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03529755 0,04528988 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03649274 0,04679882 ! phenol metabolic process GO:0018958 56 30 0,000 0,03649274 0,04677427 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03649274 0,04674974 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03649274 0,04672524 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03649274 0,04670076 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03649274 0,04667631 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03649274 0,04665189 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03649274 0,04662749 ! acute-phase response GO:0006953 50 30 0,000 0,03649274 0,04660311 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03649274 0,04657876 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03649274 0,04655444 ! myofibril assembly GO:0030239 50 30 0,000 0,03649274 0,04653014 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03649274 0,04650587 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03649274 0,04648162 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03649274 0,0464574 ! cell fate determination GO:0001709 64 30 0,000 0,03649274 0,0464332 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03649274 0,04640903 ! phospholipid transport GO:0015914 65 30 0,000 0,03649274 0,04638489 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03649274 0,04636077 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03649274 0,04633667 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03649274 0,0463126 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03649274 0,04628855 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03649274 0,04626453 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,03649274 0,04624054 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03768647 0,04772838 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03768647 0,04770365 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03768647 0,04767895 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03768647 0,04765427 ! cell junction assembly GO:0034329 85 31 0,000 0,03768647 0,04762962 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03768647 0,04760499 ! ovulation cycle process GO:0022602 55 31 0,000 0,03768647 0,04758039 ! peptide transport GO:0015833 60 31 0,000 0,03768647 0,04755581 ! male gonad development GO:0008584 56 31 0,000 0,03768647 0,04753126 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03768647 0,04750673 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03768647 0,04748223 ! detection of light stimulus GO:0009583 44 31 0,000 0,03768647 0,04745776 ! natural killer cell activation GO:0030101 50 31 0,000 0,03768647 0,04743331 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03768647 0,04740888 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03768647 0,04738448 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03768647 0,04736011 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03768647 0,04733576 ! response to heat GO:0009408 54 31 0,000 0,03768647 0,04731143 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03768647 0,04728713 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,03887876 0,04875812 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,03887876 0,0487331 ! collagen metabolic process GO:0032963 49 32 0,000 0,03887876 0,04870811 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,03887876 0,04868314 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,03887876 0,0486582 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,03887876 0,04863329 ! metanephros development GO:0001656 81 32 0,000 0,03887876 0,0486084 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,03887876 0,04858354 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,03887876 0,0485587 ! muscle cell development GO:0055001 52 32 0,000 0,03887876 0,04853389 ! mesoderm formation GO:0001707 73 32 0,000 0,03887876 0,0485091 ! ovulation cycle GO:0042698 57 32 0,000 0,03887876 0,04848434 ! peripheral nervous system development GO:0007422 68 32 0,000 0,03887876 0,0484596 ! BMP signaling pathway GO:0030509 71 32 0,000 0,03887876 0,04843489 ! hindbrain development GO:0030902 65 32 0,000 0,03887876 0,0484102 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,03887876 0,04838554 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,03887876 0,0483609 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,03887876 0,04833629 ! gene silencing GO:0016458 71 32 0,000 0,03887876 0,04831171 ! regulation of pH GO:0006885 56 33 0,000 0,04006961 0,04976617 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04006961 0,04974088 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04006961 0,04971562 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04006961 0,04969038 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04006961 0,04966517 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04006961 0,04963999 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04006961 0,04961483 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04006961 0,04958969 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04006961 0,04956458 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04006961 0,0495395 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04006961 0,04951444 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04006961 0,04948941 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04006961 0,0494644 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04006961 0,04943942 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04006961 0,04941446 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04125901 0,05085558 ! glial cell differentiation GO:0010001 67 34 0,000 0,04125901 0,05082994 ! post-embryonic development GO:0009791 76 34 0,000 0,04125901 0,05080432 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04125901 0,05077872 ! cholesterol transport GO:0030301 62 34 0,000 0,04125901 0,05075315 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04125901 0,05072761 ! spliceosome assembly GO:0000245 75 34 0,000 0,04125901 0,0507021 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04125901 0,0506766 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04125901 0,05065114 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04125901 0,0506257 ! cell fate specification GO:0001708 56 34 0,000 0,04125901 0,05060028 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04125901 0,05057489 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04125901 0,05054953 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04125901 0,05052419 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04125901 0,05049888 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04244698 0,05192687 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04244698 0,05190088 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04244698 0,05187492 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04244698 0,05184898 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04244698 0,05182307 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04244698 0,05179718 ! membrane docking GO:0022406 69 35 0,000 0,04244698 0,05177132 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04244698 0,05174549 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04244698 0,05171968 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04244698 0,0516939 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04244698 0,05166814 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04244698 0,05164241 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04244698 0,05161671 ! telencephalon development GO:0021537 81 35 0,000 0,04244698 0,05159103 ! sterol transport GO:0015918 63 35 0,000 0,04244698 0,05156537 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04244698 0,05153974 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04244698 0,05151414 ! placenta development GO:0001890 53 35 0,000 0,04244698 0,05148856 ! vesicle localization GO:0051648 70 35 0,000 0,04244698 0,05146301 ! regulation of muscle development GO:0048634 82 36 0,000 0,0436335 0,05287532 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,0436335 0,0528491 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0436335 0,05282292 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,0436335 0,05279675 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0436335 0,05277062 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0436335 0,0527445 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0436335 0,05271842 ! regulation of proteolysis GO:0030162 77 36 0,000 0,0436335 0,05269236 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0436335 0,05266633 ! aerobic respiration GO:0009060 56 36 0,000 0,0436335 0,05264032 ! cytokine production GO:0001816 68 36 0,000 0,0436335 0,05261434 ! embryonic organ development GO:0048568 67 36 0,000 0,0436335 0,05258838 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0436335 0,05256245 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04481859 0,05396344 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04481859 0,05393685 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04481859 0,0539103 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04481859 0,05388377 ! odontogenesis GO:0042476 74 37 0,000 0,04481859 0,05385726 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04481859 0,05383078 ! tissue remodeling GO:0048771 78 37 0,000 0,04481859 0,05380433 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04481859 0,05377791 ! female gonad development GO:0008585 71 37 0,000 0,04481859 0,0537515 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04481859 0,05372513 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04481859 0,05369878 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04600224 0,05508994 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04600224 0,05506295 ! organic anion transport GO:0015711 82 38 0,000 0,04600224 0,05503598 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04600224 0,05500905 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04600224 0,05498213 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04600224 0,05495525 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04600224 0,05492839 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04600224 0,05490155 ! regulation of protein stability GO:0031647 77 38 0,000 0,04600224 0,05487475 ! spermatid development GO:0007286 69 38 0,000 0,04600224 0,05484797 ! glycogen metabolic process GO:0005977 63 38 0,000 0,04600224 0,05482121 ! pigment metabolic process GO:0042440 87 38 0,000 0,04600224 0,05479448 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,04600224 0,05476778 ! neural tube formation GO:0001841 79 38 0,000 0,04600224 0,0547411 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04718446 0,05612057 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04718446 0,05609326 ! negative regulation of binding GO:0051100 71 39 0,000 0,04718446 0,05606597 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,04718446 0,05603872 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04718446 0,05601149 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04718446 0,05598429 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04718446 0,05595711 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04718446 0,05592996 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04718446 0,05590283 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04718446 0,05587574 ! glucan metabolic process GO:0044042 64 39 0,000 0,04718446 0,05584866 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,04836525 0,05721855 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,04836525 0,05719086 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,04836525 0,05716319 ! learning GO:0007612 82 40 0,000 0,04836525 0,05713555 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,04836525 0,05710793 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,04836525 0,05708034 ! lipid homeostasis GO:0055088 75 40 0,000 0,04836525 0,05705278 ! mismatch repair GO:0006298 58 40 0,000 0,04836525 0,05702525 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,04836525 0,05699774 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,04836525 0,05697026 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,04836525 0,0569428 ! RNA export from nucleus GO:0006405 61 41 0,000 0,04954461 0,05830322 ! mRNA catabolic process GO:0006402 79 41 0,000 0,04954461 0,05827515 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,04954461 0,0582471 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,04954461 0,05821909 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,04954461 0,0581911 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,04954461 0,05816313 ! gliogenesis GO:0042063 91 41 0,000 0,04954461 0,0581352 ! feeding behavior GO:0007631 69 41 0,000 0,04954461 0,05810729 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,04954461 0,05807941 ! mesenchymal cell development GO:0014031 94 41 0,000 0,04954461 0,05805155 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,04954461 0,05802372 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,04954461 0,05799592 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,04954461 0,05796814 ! spermatid differentiation GO:0048515 73 41 0,000 0,04954461 0,05794039 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,04954461 0,05791267 ! RNA modification GO:0009451 64 41 0,000 0,04954461 0,05788497 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05072254 0,05923287 ! ear morphogenesis GO:0042471 64 42 0,000 0,05072254 0,05920457 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05072254 0,0591763 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,05072254 0,05914805 ! T cell differentiation GO:0030217 93 42 0,000 0,05072254 0,05911983 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05072254 0,05909164 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05072254 0,05906347 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05072254 0,05903533 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05072254 0,05900722 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05072254 0,05897914 ! cytokinesis GO:0000910 84 42 0,000 0,05072254 0,05895108 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05072254 0,05892304 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05189904 0,0602611 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05189904 0,06023248 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05189904 0,06020387 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05189904 0,0601753 ! regulation of tube size GO:0035150 76 43 0,000 0,05189904 0,06014676 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05189904 0,06011824 ! glucose transport GO:0015758 66 43 0,000 0,05189904 0,06008974 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05189904 0,06006128 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05189904 0,06003284 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05189904 0,06000443 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05189904 0,05997605 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05189904 0,05994769 ! segmentation GO:0035282 78 43 0,000 0,05189904 0,05991936 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05189904 0,05989105 ! neuron migration GO:0001764 85 43 0,000 0,05189904 0,05986278 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05189904 0,05983453 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05307412 0,06116041 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05307412 0,06113158 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05307412 0,06110277 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,05307412 0,06107399 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05307412 0,06104523 ! hexose transport GO:0008645 68 44 0,000 0,05307412 0,06101651 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05307412 0,06098781 ! striated muscle contraction GO:0006941 85 44 0,000 0,05307412 0,06095913 ! phagocytosis GO:0006909 105 44 0,000 0,05307412 0,06093049 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05307412 0,06090187 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05424777 0,0622194 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05424777 0,0621902 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,05424777 0,06216103 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05424777 0,06213189 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05424777 0,06210277 ! biopolymer methylation GO:0043414 91 45 0,000 0,05424777 0,06207368 ! B cell differentiation GO:0030183 124 45 0,000 0,05424777 0,06204462 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05424777 0,06201559 ! female gamete generation GO:0007292 71 45 0,000 0,05424777 0,06198658 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05424777 0,0619576 ! developmental growth GO:0048589 88 45 0,000 0,05424777 0,06192865 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05424777 0,06189973 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05542001 0,06320779 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05542001 0,06317829 ! glycolysis GO:0006096 71 46 0,000 0,05542001 0,06314882 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,05542001 0,06311938 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05542001 0,06308997 ! leukocyte migration GO:0050900 75 46 0,000 0,05542001 0,06306059 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,05542001 0,06303123 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05542001 0,0630019 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05542001 0,06297259 ! pigmentation GO:0043473 103 46 0,000 0,05542001 0,06294332 ! cell growth GO:0016049 90 46 0,000 0,05542001 0,06291407 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,05542001 0,06288485 ! neural tube development GO:0021915 91 47 0,000 0,05659082 0,06418355 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05659082 0,06415377 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05659082 0,06412401 ! positive regulation of defense response GO:0031349 88 48 0,000 0,05776022 0,06541873 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,05776022 0,06538842 ! mitochondrial transport GO:0006839 94 48 0,000 0,05776022 0,06535813 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,05776022 0,06532787 ! cellular component disassembly GO:0022411 89 48 0,000 0,05776022 0,06529764 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,05776022 0,06526744 ! endosome transport GO:0016197 127 48 0,000 0,05776022 0,06523727 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,05776022 0,06520712 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,05776022 0,065177 ! male sex differentiation GO:0046661 93 48 0,000 0,05776022 0,06514691 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,05776022 0,06511685 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,05776022 0,06508681 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,05776022 0,0650568 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,05776022 0,06502682 ! methylation GO:0032259 97 48 0,000 0,05776022 0,06499687 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,05892819 0,06628065 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,05892819 0,06625015 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,05892819 0,06621968 ! JNK cascade GO:0007254 106 49 0,000 0,05892819 0,06618923 ! protein homooligomerization GO:0051260 84 49 0,000 0,05892819 0,06615881 ! regulation of action potential GO:0001508 102 50 0,000 0,06009476 0,06743752 ! regulation of ion transport GO:0043269 86 50 0,000 0,06009476 0,06740656 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06009476 0,06737563 ! endocrine system development GO:0035270 109 50 0,000 0,06009476 0,06734472 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06009476 0,06731384 ! activation of caspase activity GO:0006919 95 50 0,000 0,06009476 0,06728299 ! regulation of ossification GO:0030278 123 50 0,000 0,06009476 0,06725217 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06009476 0,06722138 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06009476 0,06719061 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06009476 0,06715988 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06009476 0,06712917 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,06125991 0,06839943 ! viral infectious cycle GO:0019058 104 51 0,000 0,06125991 0,06836818 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06125991 0,06833696 ! peptide metabolic process GO:0006518 80 51 0,000 0,06125991 0,06830577 ! response to temperature stimulus GO:0009266 84 51 0,000 0,06125991 0,06827461 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06125991 0,06824348 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06125991 0,06821238 ! positive regulation of binding GO:0051099 88 52 0,000 0,06242364 0,06947652 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06242364 0,06944488 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,06242364 0,06941327 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06242364 0,06938169 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06242364 0,06935014 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06242364 0,06931862 ! excretion GO:0007588 87 52 0,000 0,06242364 0,06928713 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,06242364 0,06925566 ! histone modification GO:0016570 104 52 0,000 0,06242364 0,06922422 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06242364 0,06919282 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06242364 0,06916144 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06242364 0,06913008 ! amino acid activation GO:0043038 98 52 0,000 0,06242364 0,06909876 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,06358597 0,0703535 ! positive regulation of growth GO:0045927 96 53 0,000 0,06358597 0,07032165 ! inner ear development GO:0048839 89 53 0,000 0,06358597 0,07028983 ! chromatin remodeling GO:0006338 122 53 0,000 0,06358597 0,07025804 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,06358597 0,07022628 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,06358597 0,07019455 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,06358597 0,07016284 ! cartilage development GO:0051216 99 53 0,000 0,06358597 0,07013117 ! synapse organization GO:0050808 102 53 0,000 0,06358597 0,07009952 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,06474689 0,07134716 ! regulation of translational initiation GO:0006446 87 54 0,000 0,06474689 0,071315 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06474689 0,07128286 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06474689 0,07125075 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06474689 0,07121867 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06474689 0,07118662 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06474689 0,07115459 ! membrane fusion GO:0006944 122 54 0,000 0,06474689 0,0711226 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06474689 0,07109063 ! covalent chromatin modification GO:0016569 115 54 0,000 0,06474689 0,0710587 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06474689 0,07102679 ! regulation of cell shape GO:0008360 142 54 0,000 0,06474689 0,07099491 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,06474689 0,07096306 ! RNA catabolic process GO:0006401 103 55 0,000 0,06590641 0,0722015 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06590641 0,07216914 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06590641 0,07213681 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06590641 0,0721045 ! cell recognition GO:0008037 98 55 0,000 0,06590641 0,07207223 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06590641 0,07203998 ! cell maturation GO:0048469 107 55 0,000 0,06590641 0,07200776 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06590641 0,07197557 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,06590641 0,07194341 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,06706452 0,0731749 ! glucose catabolic process GO:0006007 88 56 0,000 0,06706452 0,07314224 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,06706452 0,0731096 ! regulation of DNA replication GO:0006275 105 56 0,000 0,06706452 0,07307699 ! RNA elongation GO:0006354 90 56 0,000 0,06706452 0,07304441 ! chloride transport GO:0006821 102 57 0,000 0,06822122 0,07427114 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,06822122 0,07423806 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,06822122 0,07420501 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,06822122 0,07417198 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,06822122 0,07413899 ! heart morphogenesis GO:0003007 105 57 0,000 0,06822122 0,07410602 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,06822122 0,07407309 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,06822122 0,07404018 ! regulation of actin filament length GO:0030832 118 58 0,000 0,06937652 0,07526059 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,06937652 0,07522719 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,06937652 0,07519381 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,06937652 0,07516047 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,06937652 0,07512715 ! aging GO:0007568 112 58 0,000 0,06937652 0,07509386 ! gastrulation GO:0007369 122 58 0,000 0,06937652 0,07506061 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,06937652 0,07502738 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,06937652 0,07499418 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,06937652 0,07496101 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,06937652 0,07492787 ! maintenance of location GO:0051235 124 58 0,000 0,06937652 0,07489476 ! nuclear export GO:0051168 110 59 0,000 0,07053043 0,07610682 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07053043 0,07607322 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07168293 0,07728217 ! lipid modification GO:0030258 112 60 0,000 0,07168293 0,07724808 ! DNA catabolic process GO:0006308 94 60 0,000 0,07168293 0,07721402 ! regulation of endocytosis GO:0030100 104 60 0,000 0,07168293 0,07717999 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07168293 0,07714599 ! adult behavior GO:0030534 104 60 0,000 0,07168293 0,07711202 ! kidney development GO:0001822 133 60 0,000 0,07168293 0,07707808 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07283404 0,07828138 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07283404 0,07824695 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07283404 0,07821256 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07283404 0,07817819 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07283404 0,07814386 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07283404 0,07810956 ! camera-type eye development GO:0043010 126 61 0,000 0,07283404 0,07807528 ! proton transport GO:0015992 117 61 0,000 0,07283404 0,07804104 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07283404 0,07800682 ! viral reproductive process GO:0022415 132 62 0,000 0,07398376 0,07920347 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07398376 0,07916878 ! tRNA processing GO:0008033 102 62 0,000 0,07398376 0,07913412 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07398376 0,07909948 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07513208 0,08029207 ! regulation of mitosis GO:0007088 112 63 0,000 0,07513208 0,08025696 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,07513208 0,08022188 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07513208 0,08018684 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07513208 0,08015182 ! hydrogen transport GO:0006818 121 64 0,000 0,07627901 0,08133986 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07627901 0,08130437 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,07627901 0,08126891 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07627901 0,08123348 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,07627901 0,08119809 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,07742455 0,08238161 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,07742455 0,08234574 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,07742455 0,08230991 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,07742455 0,0822741 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,07742455 0,08223833 ! ear development GO:0043583 114 66 0,000 0,0785687 0,08341735 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,0785687 0,08338111 ! gonad development GO:0008406 115 66 0,000 0,0785687 0,08334491 ! activation of MAPK activity GO:0000187 124 67 0,000 0,07971146 0,08452044 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,07971146 0,08448377 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,07971146 0,08444714 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,07971146 0,08441053 ! secondary metabolic process GO:0019748 125 67 0,000 0,07971146 0,08437396 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,07971146 0,08433742 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08085284 0,085508 ! hexose catabolic process GO:0019320 113 68 0,000 0,08085284 0,085471 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08085284 0,08543403 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08085284 0,0853971 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08085284 0,08536019 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08085284 0,08532332 ! viral reproduction GO:0016032 142 68 0,000 0,08085284 0,08528648 ! regulation of lipase activity GO:0060191 137 68 0,000 0,08085284 0,08524967 ! adaptive immune response GO:0002250 126 68 0,000 0,08085284 0,08521289 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,08085284 0,08517615 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08199283 0,08633987 ! lung development GO:0030324 165 69 0,000 0,08199283 0,08630267 ! urogenital system development GO:0001655 149 69 0,000 0,08199283 0,0862655 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08199283 0,08622837 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,08199283 0,08619126 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08199283 0,08615419 ! developmental maturation GO:0021700 128 69 0,000 0,08199283 0,08611715 ! single fertilization GO:0007338 83 69 0,000 0,08199283 0,08608014 ! cell redox homeostasis GO:0045454 114 70 0,000 0,08313145 0,08723803 ! germ cell development GO:0007281 133 70 0,000 0,08313145 0,08720057 ! activation of immune response GO:0002253 120 70 0,000 0,08313145 0,08716315 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,08313145 0,08712575 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,08426868 0,08827976 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,08426868 0,08824192 ! appendage morphogenesis GO:0035107 150 72 0,000 0,08540454 0,08939301 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,08540454 0,08935472 ! respiratory tube development GO:0030323 171 72 0,000 0,08540454 0,08931647 ! B cell activation GO:0042113 179 72 0,000 0,08540454 0,08927826 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,08540454 0,08924007 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,08540454 0,08920192 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,08540454 0,0891638 ! appendage development GO:0048736 151 73 0,000 0,08653901 0,09030962 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,08653901 0,09027106 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,08653901 0,09023253 ! regulation of immune effector process GO:0002697 156 73 0,000 0,08653901 0,09019403 ! acute inflammatory response GO:0002526 118 74 0,000 0,08767212 0,09133603 ! amino acid transport GO:0006865 148 74 0,000 0,08767212 0,09129709 ! regulation of caspase activity GO:0043281 136 74 0,000 0,08767212 0,09125819 ! respiratory system development GO:0060541 175 74 0,000 0,08767212 0,09121933 ! organelle localization GO:0051640 155 74 0,000 0,08767212 0,09118049 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,08880385 0,09231821 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,08880385 0,09227894 ! reproductive structure development GO:0048608 131 75 0,000 0,08880385 0,09223971 ! axon guidance GO:0007411 162 75 0,000 0,08880385 0,09220051 ! rhythmic process GO:0048511 142 75 0,000 0,08880385 0,09216134 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,0899342 0,0932948 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,0899342 0,0932552 ! learning or memory GO:0007611 161 76 0,000 0,0899342 0,09321564 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,0899342 0,09317611 ! regulation of blood pressure GO:0008217 134 76 0,000 0,0899342 0,09313661 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,0899342 0,09309714 ! amine catabolic process GO:0009310 136 77 0,000 0,09106319 0,09422591 ! neurotransmitter transport GO:0006836 142 77 0,000 0,09106319 0,09418602 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,09106319 0,09414616 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,09106319 0,09410633 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,09106319 0,09406654 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,09106319 0,09402678 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,09106319 0,09398706 ! regulation of catabolic process GO:0009894 173 77 0,000 0,09106319 0,09394737 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,09219081 0,09507055 ! antigen processing and presentation GO:0019882 117 78 0,000 0,09219081 0,09503044 ! fertilization GO:0009566 99 78 0,000 0,09219081 0,09499036 ! blood coagulation GO:0007596 151 79 0,000 0,09331706 0,09611027 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,09331706 0,09606977 ! protein oligomerization GO:0051259 149 79 0,000 0,09331706 0,09602931 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,09331706 0,09598887 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,09444194 0,09710508 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,09444194 0,09706423 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,09444194 0,09702341 ! muscle cell differentiation GO:0042692 178 81 0,000 0,09556546 0,09813637 ! response to hypoxia GO:0001666 178 81 0,000 0,09556546 0,09809514 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,09556546 0,09805394 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,09668762 0,09916367 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,09668762 0,09912206 ! protein import into nucleus GO:0006606 174 82 0,000 0,09668762 0,09908048 ! exocytosis GO:0006887 153 83 0,000 0,09780842 0,10018699 ! response to drug GO:0042493 149 83 0,000 0,09780842 0,100145 ! response to oxygen levels GO:0070482 183 83 0,000 0,09780842 0,10010305 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,09780842 0,10006113 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,09780842 0,10001924 ! nuclear import GO:0051170 177 83 0,000 0,09780842 0,09997739 ! inorganic anion transport GO:0015698 156 83 0,000 0,09780842 0,09993558 ! T cell activation GO:0042110 189 84 0,000 0,09892786 0,10103711 ! response to nutrient GO:0007584 135 84 0,000 0,09892786 0,10099489 ! digestion GO:0007586 130 84 0,000 0,09892786 0,1009527 ! hemostasis GO:0007599 165 85 0,000 0,10004594 0,10205104 ! negative regulation of transport GO:0051051 164 85 0,000 0,10004594 0,10200845 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,10004594 0,10196589 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,10004594 0,10192337 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,10004594 0,10188088 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,10004594 0,10183843 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,10227804 0,10406716 ! mitochondrion organization GO:0007005 159 87 0,000 0,10227804 0,10402383 ! nucleosome assembly GO:0006334 126 87 0,000 0,10227804 0,10398054 ! regulation of protein transport GO:0051223 165 87 0,000 0,10227804 0,10393729 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,10339206 0,1050257 ! sensory perception of smell GO:0007608 117 88 0,000 0,10339206 0,10498204 ! chromatin assembly GO:0031497 128 88 0,000 0,10339206 0,10493843 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,10339206 0,10489485 ! regulation of DNA binding GO:0051101 167 89 0,000 0,10450473 0,10597968 ! tube morphogenesis GO:0035239 194 89 0,000 0,10450473 0,1059357 ! cellular defense response GO:0006968 123 89 0,000 0,10450473 0,10589176 ! protein localization in nucleus GO:0034504 192 89 0,000 0,10450473 0,10584786 ! regulation of neurological system process GO:0031644 175 89 0,000 0,10450473 0,105804 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,10561604 0,10688484 ! gland development GO:0048732 220 91 0,000 0,10672601 0,10796342 ! defense response to bacterium GO:0042742 112 91 0,000 0,10672601 0,10791873 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,10783464 0,10899463 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,10783464 0,10894955 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,10894192 0,11002278 ! amine transport GO:0015837 181 93 0,000 0,10894192 0,10997732 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,10894192 0,10993189 ! vitamin metabolic process GO:0006766 153 93 0,000 0,10894192 0,1098865 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,11004785 0,11095622 ! female pregnancy GO:0007565 166 94 0,000 0,11004785 0,11091044 ! sterol metabolic process GO:0016125 166 94 0,000 0,11004785 0,1108647 ! regulation of membrane potential GO:0042391 179 94 0,000 0,11004785 0,11081901 ! regulation of defense response GO:0031347 171 95 0,000 0,11115245 0,11188522 ! nucleosome organization GO:0034728 143 95 0,000 0,11115245 0,11183914 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,11115245 0,1117931 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,11115245 0,11174709 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,11115245 0,11170113 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,11115245 0,1116552 ! sex differentiation GO:0007548 171 96 0,000 0,11225571 0,11271709 ! regulation of T cell activation GO:0050863 175 96 0,000 0,11225571 0,11267078 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,11335762 0,11373005 ! transcription initiation GO:0006352 171 97 0,000 0,11335762 0,11368336 ! regulation of protein localization GO:0032880 188 97 0,000 0,11335762 0,11363671 ! leukocyte differentiation GO:0002521 232 98 0,000 0,1144582 0,11469294 ! forebrain development GO:0030900 210 98 0,000 0,1144582 0,11464592 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,11665536 0,11679879 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,11665536 0,11675094 ! positive regulation of immune response GO:0050778 175 100 0,000 0,11665536 0,11670313 ! hormone metabolic process GO:0042445 171 100 0,000 0,11665536 0,11665536