pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3796-4-real-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 7,997E-08 1,839E-04 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 1,308E-06 1,505E-03 ! fructose metabolic process GO:0006000 20 16 2,000 4,409E-06 3,38E-03 ! alditol metabolic process GO:0019400 24 20 2,000 8,925E-06 5,132E-03 ! sperm motility GO:0030317 27 24 2,000 1,576E-05 7,248E-03 ! hexose biosynthetic process GO:0019319 35 29 2,000 2,824E-05 0,01082693 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 3,818E-05 0,01254377 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 4,107E-05 0,01180757 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 4,107E-05 0,01049562 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 4,107E-05 9,446E-03 ! polyol metabolic process GO:0019751 44 34 2,000 4,593E-05 9,603E-03 ! alcohol biosynthetic process GO:0046165 45 38 2,000 6,438E-05 0,01233994 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 8,602E-05 0,01521949 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 8,602E-05 0,01413238 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 1,145E-04 0,01756417 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,471E-04 0,02114366 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,471E-04 0,01989992 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,471E-04 0,01879437 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,836E-04 0,02222765 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,836E-04 0,02111627 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 2,241E-04 0,02454794 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 3,694E-04 0,03861908 GO:0031114|regulation of microtubule depolymerization, ! regulation of protein ubiquitination GO:0031396 19 15 1,000 4,257E-04 0,04256787 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 4,257E-04 0,04079421 ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,859E-04 0,04469913 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 4,859E-04 0,04297993 ! negative regulation of translation GO:0017148 22 16 1,000 4,859E-04 0,04138808 ! response to unfolded protein GO:0006986 99 76 2,000 5,085E-04 0,04176698 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 5,283E-04 0,04190241 ! inactivation of MAPK activity GO:0000188 27 17 1,000 5,499E-04 0,04216119 ! alcohol catabolic process GO:0046164 104 80 2,000 5,909E-04 0,04384118 ! response to protein stimulus GO:0051789 111 81 2,000 6,128E-04 0,04404244 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 6,897E-04 0,0480676 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 8,448E-04 0,05714602 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 9,163E-04 0,06021573 ! carbohydrate catabolic process GO:0016052 121 93 2,000 9,163E-04 0,05854307 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 9,28E-04 0,05768908 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 1,015E-03 0,06144098 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 1,015E-03 0,05986557 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 1,098E-03 0,06314863 ! fat cell differentiation GO:0045444 37 24 1,000 1,106E-03 0,06204179 ! regulation of translation GO:0006417 151 100 2,000 1,131E-03 0,06191424 ! negative regulation of protein modification process GO:0031400 50 26 1,000 1,299E-03 0,06947843 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,299E-03 0,06789937 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,507E-03 0,07701772 ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,73E-03 0,08648073 ! response to heat GO:0009408 41 30 1,000 1,73E-03 0,08464071 ! RNA export from nucleus GO:0006405 44 33 1,000 2,091E-03 0,10020651 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 2,912E-03 0,13669666 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 2,912E-03 0,13396273 ! response to calcium ion GO:0051592 58 40 1,000 3,062E-03 0,13806996 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 3,531E-03 0,15616243 ! response to insulin stimulus GO:0032868 63 43 1,000 3,531E-03 0,15321597 ! positive regulation of cell cycle GO:0045787 77 45 1,000 3,861E-03 0,16444179 ! regulation of translational initiation GO:0006446 64 45 1,000 3,861E-03 0,16145194 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 4,031E-03 0,1655627 ! response to UV GO:0009411 75 46 1,000 4,031E-03 0,16265809 ! response to temperature stimulus GO:0009266 62 48 1,000 4,382E-03 0,1737682 ! nuclear export GO:0051168 69 48 1,000 4,382E-03 0,17082298 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 4,747E-03 0,18195054 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 4,934E-03 0,18603241 ! aging GO:0007568 79 52 1,000 5,125E-03 0,19010779 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 6,128E-03 0,22373843 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 6,128E-03 0,22024251 ! negative regulation of kinase activity GO:0033673 100 58 1,000 6,339E-03 0,22430966 ! negative regulation of transferase activity GO:0051348 105 61 1,000 6,991E-03 0,24362215 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 6,991E-03 0,239986 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 7,215E-03 0,24402412 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 7,672E-03 0,25572478 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 7,672E-03 0,25207157 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 7,905E-03 0,25608085 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 7,905E-03 0,25252417 ! regulation of actin filament-based process GO:0032970 99 66 1,000 8,142E-03 0,2565177 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 8,142E-03 0,25305125 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 8,624E-03 0,26447655 ! positive regulation of ligase activity GO:0051351 99 69 1,000 8,87E-03 0,26844179 ! response to metal ion GO:0010038 103 70 1,000 9,119E-03 0,27239755 ! eye development GO:0001654 111 70 1,000 9,119E-03 0,26890528 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 9,119E-03 0,26550141 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 9,372E-03 0,26943521 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 9,627E-03 0,27336001 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 9,627E-03 0,27002636 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01025515 0,28417899 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01025515 0,28079591 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01025515 0,27749243 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01025515 0,27426577 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01025515 0,27111329 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01025515 0,26803246 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01025515 0,26502086 ! sleep GO:0030431 11 5 0,000 0,01025515 0,26207618 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01025515 0,25919622 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01025515 0,25637887 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01025515 0,25362211 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01025515 0,250924 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01025515 0,2482827 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01025515 0,24569642 ! tongue development GO:0043586 6 5 0,000 0,01025515 0,24316347 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01025515 0,24068221 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01025515 0,23825107 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01025515 0,23586856 ! cobalt ion transport GO:0006824 9 5 0,000 0,01025515 0,23353323 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01025515 0,23124369 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01025515 0,2289986 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01025515 0,2267967 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01025515 0,22463673 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01025515 0,22251751 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01025515 0,22043791 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01025515 0,21839682 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01025515 0,21639318 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01025515 0,21442597 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01025515 0,2124942 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01025515 0,21059693 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01025515 0,20873324 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01025515 0,20690225 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01025515 0,2051031 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01025515 0,20333497 ! malate metabolic process GO:0006108 7 5 0,000 0,01025515 0,20159706 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01025515 0,19988861 ! behavioral response to pain GO:0048266 7 5 0,000 0,01025515 0,19820888 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01025515 0,19655714 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01025515 0,1949327 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01025515 0,19333489 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01025515 0,19176306 ! mating behavior GO:0007617 6 5 0,000 0,01025515 0,19021658 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01025515 0,18869485 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01025515 0,18719727 ! rhythmic behavior GO:0007622 12 5 0,000 0,01025515 0,18572328 ! copulation GO:0007620 7 5 0,000 0,01025515 0,18427231 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01025515 0,18284385 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01025515 0,18143736 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01025515 0,18005234 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01025515 0,17868831 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01025515 0,17734478 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01025515 0,17602132 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01025515 0,17471745 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01025515 0,17343277 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01025515 0,17216683 ! response to protozoan GO:0001562 9 5 0,000 0,01025515 0,17091925 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01025515 0,16968961 ! lymph vessel development GO:0001945 7 5 0,000 0,01025515 0,16847754 ! endochondral ossification GO:0001958 12 5 0,000 0,01025515 0,16728267 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01025515 0,16610462 ! parathyroid gland development GO:0060017 8 5 0,000 0,01025515 0,16494305 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01025515 0,16379761 ! anagen GO:0042640 6 5 0,000 0,01025515 0,16266797 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01025515 0,16155381 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01025515 0,1604548 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01025515 0,15937065 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01025515 0,15830105 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01025515 0,15724571 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01025515 0,15620435 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01025515 0,15517669 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01025515 0,15416246 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01025515 0,1531614 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01025515 0,15217327 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01025515 0,1511978 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01025515 0,15023475 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01025515 0,1492839 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01025515 0,14834501 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01025515 0,14741785 ! ovulation GO:0030728 6 5 0,000 0,01025515 0,14650221 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01025515 0,14559788 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01025515 0,14470464 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01025515 0,14382229 ! response to pH GO:0009268 9 5 0,000 0,01025515 0,14295064 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01025515 0,1420895 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01025515 0,14123866 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01025515 0,14039795 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01025515 0,1395672 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01025515 0,13874621 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01025515 0,13793483 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01025515 0,13713289 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01025515 0,13634021 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01025515 0,13555665 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01025515 0,13478204 ! urea metabolic process GO:0019627 6 5 0,000 0,01025515 0,13401623 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01025515 0,13325908 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01025515 0,13251043 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01025515 0,13177015 ! neutrophil activation GO:0042119 5 5 0,000 0,01025515 0,13103809 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01025515 0,13031412 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01025515 0,12959811 ! response to food GO:0032094 5 5 0,000 0,01025515 0,12888993 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01025515 0,12818944 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01025515 0,12749652 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01025515 0,12681106 ! forebrain neuron development GO:0021884 7 5 0,000 0,01025515 0,12613292 ! melanosome organization GO:0032438 7 5 0,000 0,01025515 0,125462 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01025515 0,12479818 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01025515 0,12414135 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01025515 0,12349139 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01025515 0,12284821 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01025515 0,12221169 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01025515 0,12158173 ! nucleoside transport GO:0015858 6 5 0,000 0,01025515 0,12095824 ! nucleoside salvage GO:0043174 7 5 0,000 0,01025515 0,1203411 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01025515 0,11973023 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01025515 0,11912554 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01025515 0,11852692 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01025515 0,11793428 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01025515 0,11734754 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01025515 0,11676662 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01025515 0,11619141 ! depyrimidination GO:0045008 8 5 0,000 0,01025515 0,11562184 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01025515 0,11505784 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01025515 0,1144993 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01025515 0,11394617 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01025515 0,11339835 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01025515 0,11285577 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01025515 0,11231836 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01025515 0,11178605 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01025515 0,11125876 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01025515 0,11073641 ! monocyte differentiation GO:0030224 8 5 0,000 0,01025515 0,11021895 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01025515 0,10970631 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01025515 0,10919841 ! centrosome duplication GO:0051298 5 5 0,000 0,01025515 0,10869519 ! response to UV-C GO:0010225 6 5 0,000 0,01025515 0,10819659 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01025515 0,10770254 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01025515 0,10721298 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01025515 0,10672786 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01025515 0,1062471 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01025515 0,10577066 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01025515 0,10529847 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01025515 0,10483047 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01025515 0,10436662 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01025515 0,10390686 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01025515 0,10345112 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01025515 0,10299937 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01025515 0,10255155 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01025515 0,1021076 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01025515 0,10166748 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01025515 0,10123114 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01025515 0,10079853 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01025515 0,1003696 ! neural tube patterning GO:0021532 6 5 0,000 0,01025515 0,09994431 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01025515 0,0995226 ! histone demethylation GO:0016577 9 5 0,000 0,01025515 0,09910444 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01025515 0,09868978 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01025515 0,09827857 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01025515 0,09787077 ! enteric nervous system development GO:0048484 8 5 0,000 0,01025515 0,09746635 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01025515 0,09706525 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01025515 0,09666744 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01025515 0,09627288 ! transcription termination GO:0006353 8 5 0,000 0,01025515 0,09588153 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01025515 0,09549335 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01025515 0,09510829 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01025515 0,09472633 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01025515 0,09434743 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01025515 0,09397154 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01025515 0,09359864 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01025515 0,09322868 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01025515 0,09286164 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01025515 0,09249748 ! apical protein localization GO:0045176 6 5 0,000 0,01025515 0,09213616 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01025515 0,09177765 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01025515 0,09142192 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01025515 0,09106894 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01025515 0,09071868 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01025515 0,0903711 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01025515 0,09002617 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01025515 0,08968386 ! glial cell migration GO:0008347 10 5 0,000 0,01025515 0,08934415 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01025515 0,089007 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01025515 0,08867239 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01025515 0,08834029 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01025515 0,08801066 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01025515 0,08768348 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01025515 0,08735873 ! neural plate development GO:0001840 6 5 0,000 0,01025515 0,08703637 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01025515 0,08671638 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01025515 0,08639874 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01025515 0,08608342 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01025515 0,08577039 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01025515 0,08545962 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01025515 0,08515111 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01025515 0,08484481 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01025515 0,0845407 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01025515 0,08423877 ! spindle assembly GO:0051225 5 5 0,000 0,01025515 0,08393899 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01025515 0,08364133 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01025515 0,08334578 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01025515 0,08305231 ! organ regeneration GO:0031100 7 5 0,000 0,01025515 0,0827609 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01025515 0,08247153 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01025515 0,08218417 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01025515 0,08189881 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01025515 0,08161542 GO:0055081|anion homeostasis, ! response to inorganic substance GO:0010035 115 75 1,000 0,01041162 0,08257493 ! regulation of ligase activity GO:0051340 114 75 1,000 0,01041162 0,08229117 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,01122368 0,08840573 ! cellular respiration GO:0045333 107 79 1,000 0,01150041 0,09027629 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,01178015 0,0921576 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 0,01178015 0,09184521 ! tRNA transcription GO:0009304 11 6 0,000 0,01229388 0,09552678 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01229388 0,09520514 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01229388 0,09488566 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01229388 0,09456831 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01229388 0,09425309 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01229388 0,09393995 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01229388 0,09362889 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01229388 0,09331989 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01229388 0,09301291 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01229388 0,09270795 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01229388 0,09240499 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01229388 0,09210399 ! prostate gland development GO:0030850 9 6 0,000 0,01229388 0,09180495 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01229388 0,09150785 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01229388 0,09121266 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01229388 0,09091938 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01229388 0,09062797 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01229388 0,09033842 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01229388 0,09005072 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01229388 0,08976484 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01229388 0,08948078 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01229388 0,08919851 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01229388 0,08891801 ! neuron adhesion GO:0007158 9 6 0,000 0,01229388 0,08863927 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01229388 0,08836227 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01229388 0,088087 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01229388 0,08781344 ! signal peptide processing GO:0006465 8 6 0,000 0,01229388 0,08754157 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01229388 0,08727138 ! mRNA stabilization GO:0048255 15 6 0,000 0,01229388 0,08700285 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01229388 0,08673597 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01229388 0,08647072 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01229388 0,08620709 ! opsonization GO:0008228 8 6 0,000 0,01229388 0,08594506 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01229388 0,08568462 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01229388 0,08542576 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01229388 0,08516845 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01229388 0,08491269 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01229388 0,08465846 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01229388 0,08440575 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01229388 0,08415454 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01229388 0,08390483 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01229388 0,08365659 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01229388 0,08340981 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01229388 0,08316449 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01229388 0,0829206 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01229388 0,08267815 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01229388 0,0824371 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01229388 0,08219746 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01229388 0,08195921 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01229388 0,08172233 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01229388 0,08148682 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01229388 0,08125266 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01229388 0,08101985 ! thymic T cell selection GO:0045061 12 6 0,000 0,01229388 0,08078836 ! protein lipoylation GO:0009249 10 6 0,000 0,01229388 0,08055819 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01229388 0,08032934 ! pigment granule organization GO:0048753 11 6 0,000 0,01229388 0,08010177 ! drug transport GO:0015893 6 6 0,000 0,01229388 0,0798755 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01229388 0,0796505 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01229388 0,07942676 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01229388 0,07920427 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01229388 0,07898303 ! histidine metabolic process GO:0006547 6 6 0,000 0,01229388 0,07876303 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01229388 0,07854424 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01229388 0,07832667 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01229388 0,07811029 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01229388 0,07789511 ! adenohypophysis development GO:0021984 10 6 0,000 0,01229388 0,07768112 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01229388 0,07746829 ! hyperosmotic response GO:0006972 8 6 0,000 0,01229388 0,07725663 ! microtubule nucleation GO:0007020 10 6 0,000 0,01229388 0,07704612 ! ER overload response GO:0006983 7 6 0,000 0,01229388 0,07683676 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01229388 0,07662853 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01229388 0,07642142 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01229388 0,07621543 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01229388 0,07601055 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01229388 0,07580677 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01229388 0,07560408 ! response to dietary excess GO:0002021 7 6 0,000 0,01229388 0,07540247 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01229388 0,07520193 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01229388 0,07500246 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01229388 0,07480404 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01229388 0,07460667 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01229388 0,07441033 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01229388 0,07421503 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01229388 0,07402075 ! neuron apoptosis GO:0051402 8 6 0,000 0,01229388 0,07382748 ! organic alcohol transport GO:0015850 9 6 0,000 0,01229388 0,07363522 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01229388 0,07344396 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01229388 0,07325369 ! male sex determination GO:0030238 9 6 0,000 0,01229388 0,07306441 ! carnitine transport GO:0015879 8 6 0,000 0,01229388 0,0728761 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01229388 0,07268876 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01229388 0,07250237 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01229388 0,07231695 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01229388 0,07213246 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01229388 0,07194892 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01229388 0,07176631 ! parturition GO:0007567 12 6 0,000 0,01229388 0,07158462 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01229388 0,07140385 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01229388 0,071224 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01229388 0,07104504 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01229388 0,07086698 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01229388 0,07068982 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01229388 0,07051353 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01229388 0,07033812 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01229388 0,07016359 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01229388 0,06998992 ! macrophage differentiation GO:0030225 10 6 0,000 0,01229388 0,0698171 ! astrocyte development GO:0014002 14 6 0,000 0,01229388 0,06964514 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01229388 0,06947402 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01229388 0,06930374 ! interaction with symbiont GO:0051702 8 6 0,000 0,01229388 0,06913429 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01229388 0,06896567 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01229388 0,06879787 ! eating behavior GO:0042755 6 6 0,000 0,01229388 0,06863089 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01229388 0,06846471 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01229388 0,06829934 ! response to copper ion GO:0046688 9 6 0,000 0,01229388 0,06813476 ! DNA topological change GO:0006265 8 6 0,000 0,01229388 0,06797098 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01229388 0,06780798 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01229388 0,06764576 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01229388 0,06748431 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01229388 0,06732363 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01229388 0,06716372 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01229388 0,06700456 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01229388 0,06684616 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01229388 0,0666885 ! gas homeostasis GO:0033483 11 6 0,000 0,01229388 0,06653159 ! hair follicle maturation GO:0048820 7 6 0,000 0,01229388 0,06637541 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01229388 0,06621997 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01229388 0,06606525 ! Schwann cell development GO:0014044 14 6 0,000 0,01229388 0,06591125 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01229388 0,06575797 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01229388 0,0656054 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01229388 0,06545353 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01229388 0,06530237 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01229388 0,0651519 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01229388 0,06500213 ! histone ubiquitination GO:0016574 7 6 0,000 0,01229388 0,06485304 ! regulation of meiosis GO:0040020 10 6 0,000 0,01229388 0,06470464 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01229388 0,06455691 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01229388 0,06440985 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01229388 0,06426347 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01229388 0,06411775 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01229388 0,06397268 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01229388 0,06382828 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01229388 0,06368452 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01229388 0,06354141 ! receptor internalization GO:0031623 9 6 0,000 0,01229388 0,06339894 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01229388 0,06325711 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01229388 0,06311591 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01229388 0,06297534 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01229388 0,06283539 ! protein deubiquitination GO:0016579 8 6 0,000 0,01229388 0,06269607 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01229388 0,06255736 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01229388 0,06241926 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01229388 0,06228178 ! axonal fasciculation GO:0007413 9 6 0,000 0,01229388 0,06214489 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01229388 0,06200861 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01229388 0,06187292 ! midbrain development GO:0030901 6 6 0,000 0,01229388 0,06173783 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01229388 0,06160332 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01229388 0,0614694 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01229388 0,06133607 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01229388 0,0612033 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01229388 0,06107111 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01229388 0,0609395 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01229388 0,06080844 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01229388 0,06067795 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01229388 0,06054802 ! adult feeding behavior GO:0008343 6 6 0,000 0,01229388 0,06041865 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01229388 0,06028982 ! blastocyst growth GO:0001832 15 6 0,000 0,01229388 0,06016154 ! pigment granule transport GO:0051904 12 6 0,000 0,01229388 0,06003381 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01229388 0,05990662 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01229388 0,05977997 ! catecholamine transport GO:0051937 7 6 0,000 0,01229388 0,05965385 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01229388 0,05952827 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01229388 0,05940321 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01229388 0,05927867 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01229388 0,05915466 ! protein prenylation GO:0018342 10 6 0,000 0,01229388 0,05903116 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01229388 0,05890818 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01229388 0,05878571 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01229388 0,05866375 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01229388 0,05854229 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01229388 0,05842133 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,01263721 0,05992905 ! cell cycle arrest GO:0007050 150 86 1,000 0,01352082 0,06398743 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,01352082 0,06385604 ! interphase GO:0051325 159 88 1,000 0,01412447 0,06657027 ! establishment of RNA localization GO:0051236 128 88 1,000 0,01412447 0,06643413 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01432852 0,06725634 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01432852 0,06711936 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01432852 0,06698294 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01432852 0,06684707 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01432852 0,06671175 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01432852 0,06657698 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01432852 0,06644275 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01432852 0,06630906 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01432852 0,06617591 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01432852 0,0660433 ! reproductive behavior GO:0019098 12 7 0,000 0,01432852 0,06591121 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01432852 0,06577965 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01432852 0,06564862 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01432852 0,0655181 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01432852 0,0653881 ! oligopeptide transport GO:0006857 11 7 0,000 0,01432852 0,06525862 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01432852 0,06512965 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01432852 0,06500119 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01432852 0,06487324 ! RNA methylation GO:0001510 11 7 0,000 0,01432852 0,06474579 ! pericardium development GO:0060039 8 7 0,000 0,01432852 0,06461883 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01432852 0,06449238 ! fibril organization GO:0043206 13 7 0,000 0,01432852 0,06436642 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01432852 0,06424095 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01432852 0,06411596 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01432852 0,06399147 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01432852 0,06386745 ! lipoprotein transport GO:0042953 9 7 0,000 0,01432852 0,06374392 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01432852 0,06362086 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01432852 0,06349828 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01432852 0,06337616 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01432852 0,06325452 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01432852 0,06313334 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01432852 0,06301263 ! chemosensory behavior GO:0007635 9 7 0,000 0,01432852 0,06289238 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01432852 0,06277258 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01432852 0,06265324 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01432852 0,06253435 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01432852 0,06241592 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01432852 0,06229793 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01432852 0,06218039 ! reflex GO:0060004 12 7 0,000 0,01432852 0,06206329 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01432852 0,06194663 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01432852 0,0618304 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01432852 0,06171462 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01432852 0,06159926 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01432852 0,06148434 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01432852 0,06136984 ! spinal cord patterning GO:0021511 7 7 0,000 0,01432852 0,06125577 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01432852 0,06114212 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01432852 0,0610289 ! adrenal gland development GO:0030325 17 7 0,000 0,01432852 0,06091609 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01432852 0,0608037 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01432852 0,06069172 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01432852 0,06058016 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01432852 0,060469 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01432852 0,06035825 ! endosome organization GO:0007032 10 7 0,000 0,01432852 0,06024791 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01432852 0,06013797 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01432852 0,06002842 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01432852 0,05991928 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01432852 0,05981054 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01432852 0,05970218 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01432852 0,05959422 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01432852 0,05948665 ! galactose metabolic process GO:0006012 10 7 0,000 0,01432852 0,05937947 ! vesicle fusion GO:0006906 15 7 0,000 0,01432852 0,05927267 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01432852 0,05916626 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01432852 0,05906022 ! organ growth GO:0035265 11 7 0,000 0,01432852 0,05895457 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01432852 0,05884929 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01432852 0,05874439 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01432852 0,05863987 ! retinol metabolic process GO:0042572 9 7 0,000 0,01432852 0,05853571 ! behavioral fear response GO:0001662 13 7 0,000 0,01432852 0,05843192 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01432852 0,0583285 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01432852 0,05822545 ! rRNA modification GO:0000154 12 7 0,000 0,01432852 0,05812276 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01432852 0,05802043 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01432852 0,05791846 ! response to UV-B GO:0010224 11 7 0,000 0,01432852 0,05781685 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01432852 0,0577156 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01432852 0,05761469 ! intermediate filament organization GO:0045109 11 7 0,000 0,01432852 0,05751414 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01432852 0,05741395 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01432852 0,0573141 ! fibrinolysis GO:0042730 9 7 0,000 0,01432852 0,05721459 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01432852 0,05711543 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01432852 0,05701662 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01432852 0,05691814 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01432852 0,05682001 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01432852 0,05672221 ! response to tropane GO:0014073 13 7 0,000 0,01432852 0,05662475 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01432852 0,05652762 ! melanosome localization GO:0032400 10 7 0,000 0,01432852 0,05643083 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01432852 0,05633437 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01432852 0,05623823 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01432852 0,05614243 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01432852 0,05604695 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01432852 0,05595179 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01432852 0,05585696 ! mast cell activation GO:0045576 9 7 0,000 0,01432852 0,05576244 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01432852 0,05566825 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01432852 0,05557438 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01432852 0,05548082 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01432852 0,05538757 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01432852 0,05529464 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01432852 0,05520202 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01432852 0,05510971 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01432852 0,0550177 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01432852 0,05492601 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01432852 0,05483462 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01432852 0,05474353 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01432852 0,05465274 ! response to tumor cell GO:0002347 12 7 0,000 0,01432852 0,05456226 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01432852 0,05447207 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01432852 0,05438219 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01432852 0,05429259 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01432852 0,0542033 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01432852 0,05411429 ! diuresis GO:0030146 12 7 0,000 0,01432852 0,05402558 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01432852 0,05393716 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01432852 0,05384903 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01432852 0,05376118 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01432852 0,05367362 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01432852 0,05358635 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01432852 0,05349936 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01432852 0,05341265 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01432852 0,05332622 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01432852 0,05324007 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01432852 0,0531542 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01432852 0,05306861 ! lymph node development GO:0048535 9 7 0,000 0,01432852 0,05298329 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01432852 0,05289824 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01432852 0,05281347 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01432852 0,05272897 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01432852 0,05264474 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01432852 0,05256077 ! ATP catabolic process GO:0006200 10 7 0,000 0,01432852 0,05247708 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01432852 0,05239365 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01432852 0,05231048 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01432852 0,05222758 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01432852 0,05214494 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01432852 0,05206257 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01432852 0,05198045 ! muscle adaptation GO:0043500 12 7 0,000 0,01432852 0,05189859 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01432852 0,05181699 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01432852 0,05173564 ! retina homeostasis GO:0001895 9 7 0,000 0,01432852 0,05165455 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01432852 0,05157372 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01432852 0,05149313 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01432852 0,0514128 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01432852 0,05133272 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01432852 0,05125288 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01432852 0,0511733 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01432852 0,05109396 ! RNA localization GO:0006403 135 91 1,000 0,01505157 0,05358917 ! response to virus GO:0009615 122 91 1,000 0,01505157 0,05350634 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01635909 0,05806468 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01635909 0,05797521 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01635909 0,05788602 ! axon extension GO:0048675 11 8 0,000 0,01635909 0,0577971 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01635909 0,05770845 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01635909 0,05762008 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01635909 0,05753197 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01635909 0,05744414 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01635909 0,05735657 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01635909 0,05726927 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01635909 0,05718224 ! phosphate transport GO:0006817 10 8 0,000 0,01635909 0,05709546 ! N-glycan processing GO:0006491 12 8 0,000 0,01635909 0,05700896 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01635909 0,05692271 ! UTP metabolic process GO:0046051 8 8 0,000 0,01635909 0,05683672 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01635909 0,056751 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01635909 0,05666553 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01635909 0,05658032 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01635909 0,05649536 ! succinate metabolic process GO:0006105 14 8 0,000 0,01635909 0,05641066 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01635909 0,05632621 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01635909 0,05624202 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01635909 0,05615808 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01635909 0,05607438 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01635909 0,05599094 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01635909 0,05590774 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01635909 0,05582479 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01635909 0,05574209 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01635909 0,05565963 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01635909 0,05557742 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01635909 0,05549544 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01635909 0,05541371 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01635909 0,05533222 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01635909 0,05525097 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01635909 0,05516996 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01635909 0,05508918 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01635909 0,05500864 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01635909 0,05492834 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01635909 0,05484827 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01635909 0,05476843 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01635909 0,05468882 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01635909 0,05460945 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01635909 0,05453031 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01635909 0,05445139 ! melanin metabolic process GO:0006582 12 8 0,000 0,01635909 0,0543727 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01635909 0,05429424 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01635909 0,05421601 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01635909 0,054138 ! macrophage activation GO:0042116 12 8 0,000 0,01635909 0,05406022 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01635909 0,05398266 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01635909 0,05390532 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01635909 0,0538282 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01635909 0,0537513 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01635909 0,05367462 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01635909 0,05359816 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01635909 0,05352192 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01635909 0,0534459 ! ruffle organization GO:0031529 11 8 0,000 0,01635909 0,05337009 ! osteoblast development GO:0002076 13 8 0,000 0,01635909 0,05329449 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01635909 0,05321911 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01635909 0,05314394 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01635909 0,05306899 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01635909 0,05299424 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01635909 0,05291971 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01635909 0,05284538 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01635909 0,05277126 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01635909 0,05269735 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01635909 0,05262365 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01635909 0,05255015 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01635909 0,05247686 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01635909 0,05240378 ! segment specification GO:0007379 10 8 0,000 0,01635909 0,05233089 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01635909 0,05225821 ! cellular extravasation GO:0045123 11 8 0,000 0,01635909 0,05218573 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01635909 0,05211345 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01635909 0,05204137 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01635909 0,05196949 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01635909 0,05189781 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01635909 0,05182632 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01635909 0,05175504 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01635909 0,05168394 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01635909 0,05161305 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01635909 0,05154234 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01635909 0,05147183 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01635909 0,05140152 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01635909 0,05133139 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01635909 0,05126146 ! icosanoid secretion GO:0032309 12 8 0,000 0,01635909 0,05119172 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01635909 0,05112216 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01635909 0,0510528 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01635909 0,05098362 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01635909 0,05091463 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01635909 0,05084583 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01635909 0,05077721 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01635909 0,05070877 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01635909 0,05064053 ! sterol catabolic process GO:0016127 9 8 0,000 0,01635909 0,05057246 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01635909 0,05050458 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01635909 0,05043688 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01635909 0,05036936 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01635909 0,05030202 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01635909 0,05023486 ! prophase GO:0051324 11 8 0,000 0,01635909 0,05016788 ! S phase GO:0051320 8 8 0,000 0,01635909 0,05010108 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01635909 0,05003446 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01635909 0,04996801 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01635909 0,04990174 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01635909 0,04983564 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01635909 0,04976972 ! hormone catabolic process GO:0042447 13 8 0,000 0,01635909 0,04970398 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01635909 0,0496384 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01635909 0,04957301 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01635909 0,04950778 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01635909 0,04944272 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01635909 0,04937784 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01635909 0,04931312 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01635909 0,04924857 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01635909 0,0491842 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01635909 0,04911999 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01635909 0,04905595 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01635909 0,04899207 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01635909 0,04892836 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01635909 0,04886482 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01635909 0,04880144 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01635909 0,04873823 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01635909 0,04867518 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,01665354 0,04948726 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01665354 0,0494234 ! response to light stimulus GO:0009416 153 96 1,000 0,01665354 0,04935971 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,01798536 0,05323853 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01838559 0,05435329 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01838559 0,05428352 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01838559 0,05421393 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01838559 0,05414451 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01838559 0,05407527 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01838559 0,05400621 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01838559 0,05393732 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01838559 0,05386861 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01838559 0,05380008 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01838559 0,05373172 ! GTP metabolic process GO:0046039 9 9 0,000 0,01838559 0,05366353 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01838559 0,05359552 ! social behavior GO:0035176 14 9 0,000 0,01838559 0,05352767 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01838559 0,05346 ! artery development GO:0060840 19 9 0,000 0,01838559 0,0533925 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01838559 0,05332517 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01838559 0,05325801 ! response to pain GO:0048265 16 9 0,000 0,01838559 0,05319102 ! protein complex disassembly GO:0043241 17 9 0,000 0,01838559 0,0531242 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01838559 0,05305754 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01838559 0,05299106 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01838559 0,05292473 ! lung alveolus development GO:0048286 17 9 0,000 0,01838559 0,05285858 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01838559 0,05279259 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01838559 0,05272676 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01838559 0,0526611 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01838559 0,0525956 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01838559 0,05253026 ! protein targeting to ER GO:0045047 19 9 0,000 0,01838559 0,05246509 ! T cell selection GO:0045058 18 9 0,000 0,01838559 0,05240008 ! endoderm development GO:0007492 12 9 0,000 0,01838559 0,05233523 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01838559 0,05227053 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01838559 0,052206 ! arginine catabolic process GO:0006527 10 9 0,000 0,01838559 0,05214163 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01838559 0,05207742 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01838559 0,05201336 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01838559 0,05194946 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01838559 0,05188572 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01838559 0,05182214 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01838559 0,05175871 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01838559 0,05169543 ! mannose metabolic process GO:0006013 9 9 0,000 0,01838559 0,05163231 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01838559 0,05156934 ! receptor clustering GO:0043113 15 9 0,000 0,01838559 0,05150653 ! epithelial cell development GO:0002064 10 9 0,000 0,01838559 0,05144387 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01838559 0,05138136 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01838559 0,05131901 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01838559 0,0512568 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01838559 0,05119475 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01838559 0,05113284 ! motor axon guidance GO:0008045 14 9 0,000 0,01838559 0,05107109 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01838559 0,05100948 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01838559 0,05094803 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01838559 0,05088672 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01838559 0,05082556 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01838559 0,05076454 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01838559 0,05070367 ! DNA ligation GO:0006266 14 9 0,000 0,01838559 0,05064295 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01838559 0,05058237 ! response to amine stimulus GO:0014075 13 9 0,000 0,01838559 0,05052194 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01838559 0,05046165 ! erythrocyte development GO:0048821 11 9 0,000 0,01838559 0,0504015 ! renal water homeostasis GO:0003091 14 9 0,000 0,01838559 0,0503415 ! postreplication repair GO:0006301 11 9 0,000 0,01838559 0,05028164 ! mRNA cleavage GO:0006379 13 9 0,000 0,01838559 0,05022193 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01838559 0,05016235 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01838559 0,05010292 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01838559 0,05004362 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01838559 0,04998447 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01838559 0,04992546 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01838559 0,04986658 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01838559 0,04980785 ! acid secretion GO:0046717 14 9 0,000 0,01838559 0,04974925 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01838559 0,04969079 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01838559 0,04963247 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01838559 0,04957428 ! purine base metabolic process GO:0006144 18 9 0,000 0,01838559 0,04951623 ! oocyte differentiation GO:0009994 12 9 0,000 0,01838559 0,04945832 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01838559 0,04940054 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01838559 0,0493429 ! spleen development GO:0048536 15 9 0,000 0,01838559 0,04928539 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01838559 0,04922801 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01838559 0,04917077 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01838559 0,04911366 ! detection of calcium ion GO:0005513 13 9 0,000 0,01838559 0,04905669 ! blastocyst formation GO:0001825 12 9 0,000 0,01838559 0,04899984 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01838559 0,04894313 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01838559 0,04888655 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01838559 0,0488301 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01838559 0,04877377 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01838559 0,04871758 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01838559 0,04866152 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01838559 0,04860559 ! prepulse inhibition GO:0060134 14 9 0,000 0,01838559 0,04854978 ! embryonic placenta development GO:0001892 12 9 0,000 0,01838559 0,04849411 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01838559 0,04843856 ! insulin secretion GO:0030073 17 9 0,000 0,01838559 0,04838314 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01838559 0,04832784 ! response to nicotine GO:0035094 16 9 0,000 0,01838559 0,04827267 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01838559 0,04821763 ! nucleus localization GO:0051647 15 9 0,000 0,01838559 0,04816271 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01838559 0,04810792 ! localization within membrane GO:0051668 15 9 0,000 0,01838559 0,04805325 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02040803 0,05327864 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02040803 0,05321823 ! neuron fate specification GO:0048665 11 10 0,000 0,02040803 0,05315796 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02040803 0,05309783 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02040803 0,05303783 ! thyroid gland development GO:0030878 19 10 0,000 0,02040803 0,05297797 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02040803 0,05291824 ! synapsis GO:0007129 13 10 0,000 0,02040803 0,05285865 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02040803 0,05279919 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02040803 0,05273986 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02040803 0,05268067 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02040803 0,05262161 ! sulfate transport GO:0008272 12 10 0,000 0,02040803 0,05256269 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02040803 0,05250389 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02040803 0,05244523 ! androgen metabolic process GO:0008209 13 10 0,000 0,02040803 0,05238669 ! phospholipid efflux GO:0033700 16 10 0,000 0,02040803 0,05232829 ! hippocampus development GO:0021766 19 10 0,000 0,02040803 0,05227002 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,02040803 0,05221188 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02040803 0,05215386 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02040803 0,05209598 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02040803 0,05203822 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02040803 0,0519806 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02040803 0,05192309 ! pathogenesis GO:0009405 13 10 0,000 0,02040803 0,05186572 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02040803 0,05180847 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02040803 0,05175135 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02040803 0,05169436 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02040803 0,05163749 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02040803 0,05158074 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02040803 0,05152412 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02040803 0,05146763 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02040803 0,05141126 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02040803 0,05135501 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02040803 0,05129888 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02040803 0,05124288 ! response to X-ray GO:0010165 16 10 0,000 0,02040803 0,051187 ! B cell proliferation GO:0042100 14 10 0,000 0,02040803 0,05113124 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02040803 0,0510756 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02040803 0,05102008 ! forebrain cell migration GO:0021885 17 10 0,000 0,02040803 0,05096469 ! lipid digestion GO:0044241 15 10 0,000 0,02040803 0,05090941 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02040803 0,05085426 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02040803 0,05079922 ! UV protection GO:0009650 14 10 0,000 0,02040803 0,0507443 ! entry into host cell GO:0030260 20 10 0,000 0,02040803 0,0506895 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02040803 0,05063482 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02040803 0,05058026 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02040803 0,05052581 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02040803 0,05047148 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02040803 0,05041727 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02040803 0,05036317 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02040803 0,05030919 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02040803 0,05025533 ! regulation of organ growth GO:0046620 11 10 0,000 0,02040803 0,05020158 ! response to dsRNA GO:0043331 18 10 0,000 0,02040803 0,05014795 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02040803 0,05009443 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02040803 0,05004102 ! embryonic axis specification GO:0000578 12 10 0,000 0,02040803 0,04998773 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02040803 0,04993455 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02040803 0,04988149 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02040803 0,04982853 ! cranial nerve development GO:0021545 12 10 0,000 0,02040803 0,04977569 ! fucose catabolic process GO:0019317 16 10 0,000 0,02040803 0,04972296 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02040803 0,04967035 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02040803 0,04961784 ! protein sumoylation GO:0016925 12 10 0,000 0,02040803 0,04956545 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02040803 0,04951316 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02040803 0,04946099 ! zymogen activation GO:0031638 14 10 0,000 0,02040803 0,04940892 ! salivary gland development GO:0007431 22 10 0,000 0,02040803 0,04935697 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02040803 0,04930512 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02040803 0,04925339 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02040803 0,04920176 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02040803 0,04915024 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02040803 0,04909883 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02040803 0,04904752 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02040803 0,04899632 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02040803 0,04894523 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02040803 0,04889425 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02040803 0,04884337 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02040803 0,0487926 ! detection of bacterium GO:0016045 10 10 0,000 0,02040803 0,04874193 ! embryonic gut development GO:0048566 11 10 0,000 0,02040803 0,04869137 ! activation of innate immune response GO:0002218 10 10 0,000 0,02040803 0,04864091 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02040803 0,04859056 ! developmental induction GO:0031128 13 10 0,000 0,02040803 0,04854031 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02040803 0,04849016 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02040803 0,04844012 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02040803 0,04839018 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02040803 0,04834035 ! rRNA transcription GO:0009303 17 11 0,000 0,02242642 0,05306664 ! respiratory burst GO:0045730 14 11 0,000 0,02242642 0,0530121 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02242642 0,05295767 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02242642 0,05290336 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02242642 0,05284915 ! virus-host interaction GO:0019048 17 11 0,000 0,02242642 0,05279506 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02242642 0,05274108 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02242642 0,05268721 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02242642 0,05263344 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02242642 0,05257979 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02242642 0,05252625 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02242642 0,05247281 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02242642 0,05241949 ! mating GO:0007618 14 11 0,000 0,02242642 0,05236627 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02242642 0,05231316 ! T cell proliferation GO:0042098 20 11 0,000 0,02242642 0,05226016 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02242642 0,05220726 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02242642 0,05215447 ! bone resorption GO:0045453 16 11 0,000 0,02242642 0,05210179 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02242642 0,05204922 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02242642 0,05199675 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02242642 0,05194439 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02242642 0,05189213 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02242642 0,05183997 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02242642 0,05178793 ! syncytium formation GO:0006949 15 11 0,000 0,02242642 0,05173598 ! plasma membrane organization GO:0007009 18 11 0,000 0,02242642 0,05168414 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02242642 0,05163241 ! focal adhesion formation GO:0048041 24 11 0,000 0,02242642 0,05158077 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02242642 0,05152925 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02242642 0,05147782 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02242642 0,0514265 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02242642 0,05137527 ! adult heart development GO:0007512 11 11 0,000 0,02242642 0,05132415 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02242642 0,05127314 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02242642 0,05122222 ! temperature homeostasis GO:0001659 16 11 0,000 0,02242642 0,0511714 ! L-glutamate transport GO:0015813 16 11 0,000 0,02242642 0,05112069 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02242642 0,05107007 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02242642 0,05101956 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02242642 0,05096915 ! stem cell development GO:0048864 29 11 0,000 0,02242642 0,05091883 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02242642 0,05086861 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02242642 0,0508185 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02242642 0,05076848 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02242642 0,05071856 ! vasoconstriction GO:0042310 15 11 0,000 0,02242642 0,05066874 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02242642 0,05061901 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02242642 0,05056939 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02242642 0,05051986 ! ribosome assembly GO:0042255 13 11 0,000 0,02242642 0,05047043 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02242642 0,05042109 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02242642 0,05037185 ! chromatin silencing GO:0006342 19 11 0,000 0,02242642 0,05032271 ! nucleosome positioning GO:0016584 13 11 0,000 0,02242642 0,05027366 ! T cell homeostasis GO:0043029 20 11 0,000 0,02242642 0,05022471 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02242642 0,05017585 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02242642 0,05012709 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02242642 0,05007842 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02242642 0,05002985 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02242642 0,04998137 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02242642 0,04993299 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02242642 0,0498847 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02242642 0,0498365 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02242642 0,04978839 ! male genitalia development GO:0030539 13 11 0,000 0,02242642 0,04974038 ! cholesterol efflux GO:0033344 19 11 0,000 0,02242642 0,04969246 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02242642 0,04964463 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02242642 0,0495969 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02242642 0,04954926 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02242642 0,0495017 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02242642 0,04945424 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02242642 0,04940687 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02242642 0,04935959 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02242642 0,0493124 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02242642 0,04926531 ! lysogeny GO:0030069 18 11 0,000 0,02242642 0,0492183 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02242642 0,04917138 ! acrosome reaction GO:0007340 13 11 0,000 0,02242642 0,04912455 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02242642 0,04907781 ! lactation GO:0007595 20 12 0,000 0,02444077 0,05343514 ! reproductive cellular process GO:0048610 14 12 0,000 0,02444077 0,0533844 ! tRNA modification GO:0006400 14 12 0,000 0,02444077 0,05333375 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02444077 0,0532832 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02444077 0,05323274 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02444077 0,05318238 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02444077 0,05313211 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02444077 0,05308194 ! non-recombinational repair GO:0000726 19 12 0,000 0,02444077 0,05303186 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02444077 0,05298188 ! peroxisomal transport GO:0043574 21 12 0,000 0,02444077 0,05293199 ! cartilage condensation GO:0001502 18 12 0,000 0,02444077 0,05288219 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02444077 0,05283249 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02444077 0,05278288 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02444077 0,05273337 ! heart looping GO:0001947 15 12 0,000 0,02444077 0,05268395 ! palate development GO:0060021 15 12 0,000 0,02444077 0,05263462 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02444077 0,05258538 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02444077 0,05253624 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02444077 0,05248718 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02444077 0,05243822 ! arginine metabolic process GO:0006525 13 12 0,000 0,02444077 0,05238935 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02444077 0,05234057 ! methionine metabolic process GO:0006555 13 12 0,000 0,02444077 0,05229188 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02444077 0,05224328 ! Golgi organization GO:0007030 18 12 0,000 0,02444077 0,05219477 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02444077 0,05214636 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02444077 0,05209803 ! monoamine transport GO:0015844 13 12 0,000 0,02444077 0,05204979 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02444077 0,05200164 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02444077 0,05195358 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02444077 0,05190561 ! L-amino acid transport GO:0015807 20 12 0,000 0,02444077 0,05185772 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02444077 0,05180993 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02444077 0,05176222 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02444077 0,0517146 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02444077 0,05166707 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02444077 0,05161963 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02444077 0,05157227 ! cerebellum development GO:0021549 13 12 0,000 0,02444077 0,051525 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02444077 0,05147781 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02444077 0,05143072 ! histone acetylation GO:0016573 23 12 0,000 0,02444077 0,0513837 ! histone methylation GO:0016571 15 12 0,000 0,02444077 0,05133678 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02444077 0,05128994 ! gland morphogenesis GO:0022612 23 12 0,000 0,02444077 0,05124318 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02444077 0,05119651 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02444077 0,05114993 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02444077 0,05110343 ! response to gamma radiation GO:0010332 20 12 0,000 0,02444077 0,05105701 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02444077 0,05101068 ! intestinal absorption GO:0050892 19 12 0,000 0,02444077 0,05096444 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02444077 0,05091827 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02444077 0,05087219 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02444077 0,0508262 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02444077 0,05078028 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02444077 0,05073445 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02444077 0,0506887 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02444077 0,05064304 ! microspike assembly GO:0030035 23 12 0,000 0,02444077 0,05059745 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02444077 0,05055195 ! response to cold GO:0009409 14 12 0,000 0,02444077 0,05050653 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02645108 0,05461175 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02645108 0,05456277 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02645108 0,05451388 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02645108 0,05446507 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02645108 0,05441636 ! water transport GO:0006833 17 13 0,000 0,02645108 0,05436773 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02645108 0,05431918 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02645108 0,05427073 ! lipid localization GO:0010876 24 13 0,000 0,02645108 0,05422236 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02645108 0,05417408 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02645108 0,05412588 ! organelle fusion GO:0048284 28 13 0,000 0,02645108 0,05407777 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02645108 0,05402974 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02645108 0,0539818 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02645108 0,05393394 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02645108 0,05388617 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02645108 0,05383848 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02645108 0,05379088 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02645108 0,05374336 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02645108 0,05369593 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02645108 0,05364858 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02645108 0,05360131 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02645108 0,05355413 ! NAD metabolic process GO:0019674 21 13 0,000 0,02645108 0,05350702 ! exocrine system development GO:0035272 27 13 0,000 0,02645108 0,05346001 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02645108 0,05341307 ! bone mineralization GO:0030282 15 13 0,000 0,02645108 0,05336622 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02645108 0,05331945 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02645108 0,05327276 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02645108 0,05322615 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02645108 0,05317962 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02645108 0,05313318 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02645108 0,05308681 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02645108 0,05304053 ! genitalia development GO:0048806 15 13 0,000 0,02645108 0,05299433 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02645108 0,0529482 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02645108 0,05290216 ! cellular pigmentation GO:0033059 24 13 0,000 0,02645108 0,0528562 ! tissue regeneration GO:0042246 21 13 0,000 0,02645108 0,05281032 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02645108 0,05276452 ! cofactor transport GO:0051181 19 13 0,000 0,02645108 0,05271879 ! NADP metabolic process GO:0006739 18 13 0,000 0,02645108 0,05267315 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02645108 0,05262758 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02645108 0,0525821 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02645108 0,05253669 ! gas transport GO:0015669 18 13 0,000 0,02645108 0,05249136 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02645108 0,05244611 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02645108 0,05240094 ! regulation of axon extension GO:0030516 23 13 0,000 0,02645108 0,05235584 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02645108 0,05231082 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02645108 0,05226588 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02645108 0,05222102 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02645108 0,05217623 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02645108 0,05213152 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02645108 0,05208689 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02845736 0,05598968 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02845736 0,05594183 ! superoxide anion generation GO:0042554 18 14 0,000 0,02845736 0,05589406 ! neuron maturation GO:0042551 21 14 0,000 0,02845736 0,05584636 ! regulation of S phase GO:0033261 18 14 0,000 0,02845736 0,05579875 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02845736 0,05575123 ! myotube differentiation GO:0014902 21 14 0,000 0,02845736 0,05570378 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02845736 0,05565641 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02845736 0,05560912 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02845736 0,05556192 ! inositol metabolic process GO:0006020 20 14 0,000 0,02845736 0,05551479 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02845736 0,05546774 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02845736 0,05542078 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02845736 0,05537389 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02845736 0,05532708 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02845736 0,05528035 ! response to cAMP GO:0051591 19 14 0,000 0,02845736 0,0552337 ! limbic system development GO:0021761 25 14 0,000 0,02845736 0,05518713 ! startle response GO:0001964 21 14 0,000 0,02845736 0,05514064 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02845736 0,05509422 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02845736 0,05504789 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02845736 0,05500163 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02845736 0,05495545 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02845736 0,05490934 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02845736 0,05486332 ! glycine metabolic process GO:0006544 22 14 0,000 0,02845736 0,05481737 ! pituitary gland development GO:0021983 23 14 0,000 0,02845736 0,0547715 ! cellular response to starvation GO:0009267 21 14 0,000 0,02845736 0,0547257 ! lysosomal transport GO:0007041 20 14 0,000 0,02845736 0,05467998 ! regulation of heart rate GO:0002027 23 14 0,000 0,02845736 0,05463434 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02845736 0,05458877 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02845736 0,05454328 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02845736 0,05449787 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02845736 0,05445253 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02845736 0,05440726 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02845736 0,05436208 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02845736 0,05431696 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02845736 0,05427192 ! axon cargo transport GO:0008088 27 14 0,000 0,02845736 0,05422696 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02845736 0,05418207 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02845736 0,05413725 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02845736 0,05409251 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02845736 0,05404784 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02845736 0,05400325 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02845736 0,05395873 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02845736 0,05391428 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02845736 0,05386991 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02845736 0,05382561 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02845736 0,05378138 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02845736 0,05373722 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02845736 0,05369314 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02845736 0,05364913 ! muscle maintenance GO:0046716 19 14 0,000 0,02845736 0,05360519 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02845736 0,05356132 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02845736 0,05351753 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02845736 0,05347381 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02845736 0,05343015 ! cell killing GO:0001906 20 14 0,000 0,02845736 0,05338657 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02845736 0,05334306 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02845736 0,05329962 ! cilium assembly GO:0042384 20 14 0,000 0,02845736 0,05325626 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02845736 0,05321296 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03045963 0,05691076 ! metencephalon development GO:0022037 19 15 0,000 0,03045963 0,05686456 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03045963 0,05681845 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03045963 0,0567724 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03045963 0,05672643 ! skin development GO:0043588 25 15 0,000 0,03045963 0,05668054 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03045963 0,05663472 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03045963 0,05658897 ! lipid phosphorylation GO:0046834 23 15 0,000 0,03045963 0,0565433 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03045963 0,0564977 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03045963 0,05645217 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03045963 0,05640672 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03045963 0,05636134 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03045963 0,05631603 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03045963 0,0562708 ! adult walking behavior GO:0007628 25 15 0,000 0,03045963 0,05622564 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03045963 0,05618055 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03045963 0,05613553 ! myoblast differentiation GO:0045445 27 15 0,000 0,03045963 0,05609059 ! centrosome cycle GO:0007098 16 15 0,000 0,03045963 0,05604572 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03045963 0,05600091 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03045963 0,05595619 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03045963 0,05591153 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03045963 0,05586694 ! cerebral cortex development GO:0021987 29 15 0,000 0,03045963 0,05582243 ! response to osmotic stress GO:0006970 22 15 0,000 0,03045963 0,05577798 ! vesicle coating GO:0006901 25 15 0,000 0,03045963 0,05573361 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03045963 0,0556893 ! DNA integration GO:0015074 22 15 0,000 0,03045963 0,05564507 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03045963 0,05560091 ! peptide secretion GO:0002790 27 15 0,000 0,03045963 0,05555682 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03045963 0,05551279 ! regulation of vasodilation GO:0042312 24 15 0,000 0,03045963 0,05546884 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03045963 0,05542496 ! neuron recognition GO:0008038 22 15 0,000 0,03045963 0,05538114 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03045963 0,0553374 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03045963 0,05529372 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03045963 0,05525011 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03045963 0,05520658 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03045963 0,05516311 ! biomineral formation GO:0031214 18 15 0,000 0,03045963 0,0551197 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03045963 0,05507637 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03045963 0,05503311 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03045963 0,05498991 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03045963 0,05494678 ! organic cation transport GO:0015695 19 15 0,000 0,03045963 0,05490372 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03045963 0,05486072 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03045963 0,0548178 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03045963 0,05477494 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03045963 0,05473214 ! defense response to virus GO:0051607 27 15 0,000 0,03045963 0,05468942 ! peptide hormone processing GO:0016486 19 15 0,000 0,03045963 0,05464676 ! protein secretion GO:0009306 27 16 0,000 0,03245788 0,05818638 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03245788 0,05814106 ! hormone secretion GO:0046879 25 16 0,000 0,03245788 0,05809581 ! bone remodeling GO:0046849 24 16 0,000 0,03245788 0,05805064 ! endothelial cell migration GO:0043542 22 16 0,000 0,03245788 0,05800553 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03245788 0,0579605 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03245788 0,05791553 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03245788 0,05787064 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03245788 0,05782581 ! glial cell development GO:0021782 24 16 0,000 0,03245788 0,05778105 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03245788 0,05773637 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03245788 0,05769175 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03245788 0,0576472 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03245788 0,05760272 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03245788 0,05755831 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03245788 0,05751396 ! regulation of protein binding GO:0043393 27 16 0,000 0,03245788 0,05746969 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03245788 0,05742548 ! protein export from nucleus GO:0006611 24 16 0,000 0,03245788 0,05738134 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03245788 0,05733727 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03245788 0,05729326 ! DNA replication initiation GO:0006270 25 16 0,000 0,03245788 0,05724933 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03245788 0,05720546 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03245788 0,05716166 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03245788 0,05711792 ! diencephalon development GO:0021536 25 16 0,000 0,03245788 0,05707425 ! oogenesis GO:0048477 23 16 0,000 0,03245788 0,05703065 ! neural crest cell migration GO:0001755 24 16 0,000 0,03245788 0,05698712 ! G1 phase GO:0051318 27 16 0,000 0,03245788 0,05694365 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03245788 0,05690025 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03245788 0,05685691 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03245788 0,05681364 ! steroid catabolic process GO:0006706 22 16 0,000 0,03245788 0,05677043 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03245788 0,0567273 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03245788 0,05668422 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03245788 0,05664122 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03245788 0,05659827 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03245788 0,0565554 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03245788 0,05651258 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03245788 0,05646983 ! nerve development GO:0021675 18 16 0,000 0,03245788 0,05642715 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03245788 0,05638453 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03245788 0,05634198 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03445213 0,05975859 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03445213 0,05971356 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03445213 0,05966859 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03445213 0,05962369 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03445213 0,05957886 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03445213 0,0595341 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03445213 0,05948941 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03445213 0,05944478 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03445213 0,05940022 ! signal complex assembly GO:0007172 29 17 0,000 0,03445213 0,05935572 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03445213 0,05931129 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03445213 0,05926693 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03445213 0,05922264 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03445213 0,05917841 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03445213 0,05913425 ! memory GO:0007613 25 17 0,000 0,03445213 0,05909015 ! keratinization GO:0031424 17 17 0,000 0,03445213 0,05904612 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03445213 0,05900215 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03445213 0,05895825 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03445213 0,05891442 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03445213 0,05887065 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03445213 0,05882694 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03445213 0,0587833 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03445213 0,05873973 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03445213 0,05869621 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03445213 0,05865277 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03445213 0,05860939 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03445213 0,05856607 ! membrane budding GO:0006900 29 17 0,000 0,03445213 0,05852281 ! heme metabolic process GO:0042168 27 17 0,000 0,03445213 0,05847962 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03445213 0,0584365 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03445213 0,05839343 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03445213 0,05835043 ! body fluid secretion GO:0007589 27 17 0,000 0,03445213 0,0583075 ! stem cell differentiation GO:0048863 36 17 0,000 0,03445213 0,05826462 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03445213 0,05822181 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03445213 0,05817907 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03445213 0,05813638 ! sensory perception of pain GO:0019233 23 17 0,000 0,03445213 0,05809376 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03445213 0,0580512 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03445213 0,0580087 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03445213 0,05796627 ! synaptogenesis GO:0007416 24 17 0,000 0,03445213 0,0579239 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03445213 0,05788158 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03445213 0,05783934 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03445213 0,05779715 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03445213 0,05775502 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03445213 0,05771296 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03445213 0,05767095 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03445213 0,05762901 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03445213 0,05758713 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03445213 0,05754531 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03445213 0,05750355 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03644238 0,06078134 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03644238 0,06073729 ! positive regulation of translation GO:0045727 28 18 0,000 0,03644238 0,06069331 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03644238 0,0606494 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03644238 0,06060554 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03644238 0,06056175 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03644238 0,06051803 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03644238 0,06047436 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03644238 0,06043076 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03644238 0,06038722 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03644238 0,06034375 ! axis specification GO:0009798 26 18 0,000 0,03644238 0,06030033 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03644238 0,06025698 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03644238 0,0602137 ! pancreas development GO:0031016 26 18 0,000 0,03644238 0,06017047 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03644238 0,06012731 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03644238 0,0600842 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03644238 0,06004116 ! response to retinoic acid GO:0032526 25 18 0,000 0,03644238 0,05999819 ! pigmentation during development GO:0048066 31 18 0,000 0,03644238 0,05995527 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03644238 0,05991241 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03644238 0,05986962 ! fucose metabolic process GO:0006004 26 18 0,000 0,03644238 0,05982688 ! response to fungus GO:0009620 19 18 0,000 0,03644238 0,05978421 ! peptide cross-linking GO:0018149 31 18 0,000 0,03644238 0,0597416 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03644238 0,05969905 ! heart process GO:0003015 27 18 0,000 0,03644238 0,05965656 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03644238 0,05961413 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03644238 0,05957176 ! visual learning GO:0008542 35 18 0,000 0,03644238 0,05952945 ! somitogenesis GO:0001756 24 18 0,000 0,03644238 0,0594872 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03644238 0,05944501 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03644238 0,05940288 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03644238 0,05936081 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03644238 0,0593188 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03644238 0,05927685 ! vitamin transport GO:0051180 24 18 0,000 0,03644238 0,05923496 ! hormone transport GO:0009914 27 18 0,000 0,03644238 0,05919313 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03644238 0,05915135 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03644238 0,05910964 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03644238 0,05906798 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03644238 0,05902638 ! cell-cell recognition GO:0009988 20 18 0,000 0,03644238 0,05898485 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03644238 0,05894337 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03644238 0,05890194 ! regulation of glucose import GO:0046324 21 18 0,000 0,03644238 0,05886058 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03644238 0,05881927 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03644238 0,05877803 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03644238 0,05873684 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03644238 0,0586957 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03842864 0,06185155 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03842864 0,0618083 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,03842864 0,06176511 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03842864 0,06172197 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03842864 0,0616789 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03842864 0,06163589 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03842864 0,06159294 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03842864 0,06155005 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03842864 0,06150721 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03842864 0,06146444 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03842864 0,06142173 ! regeneration GO:0031099 32 19 0,000 0,03842864 0,06137907 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03842864 0,06133648 ! response to alkaloid GO:0043279 32 19 0,000 0,03842864 0,06129394 ! sensory perception of taste GO:0050909 23 19 0,000 0,03842864 0,06125147 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03842864 0,06120905 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03842864 0,06116669 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03842864 0,06112439 ! peroxisome organization GO:0007031 29 19 0,000 0,03842864 0,06108215 ! digestive system process GO:0022600 30 19 0,000 0,03842864 0,06103996 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03842864 0,06099784 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03842864 0,06095577 ! response to vitamin A GO:0033189 26 19 0,000 0,03842864 0,06091376 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03842864 0,06087181 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03842864 0,06082992 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03842864 0,06078808 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03842864 0,0607463 ! response to starvation GO:0042594 30 19 0,000 0,03842864 0,06070458 ! sex determination GO:0007530 29 19 0,000 0,03842864 0,06066292 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03842864 0,06062131 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03842864 0,06057976 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03842864 0,06053827 ! cytolysis GO:0019835 20 19 0,000 0,03842864 0,06049683 ! renal system process GO:0003014 35 19 0,000 0,03842864 0,06045545 ! vasodilation GO:0042311 33 19 0,000 0,03842864 0,06041413 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03842864 0,06037286 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03842864 0,06033165 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03842864 0,0602905 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03842864 0,0602494 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03842864 0,06020836 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03842864 0,06016737 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03842864 0,06012644 ! sarcomere organization GO:0045214 23 19 0,000 0,03842864 0,06008557 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03842864 0,06004475 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03842864 0,06000398 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03842864 0,05996328 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03842864 0,05992262 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03842864 0,05988202 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03842864 0,05984148 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03842864 0,05980099 ! protein stabilization GO:0050821 26 19 0,000 0,03842864 0,05976056 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04041092 0,06280075 ! iron ion transport GO:0006826 37 20 0,000 0,04041092 0,06275835 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04041092 0,062716 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04041092 0,06267371 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04041092 0,06263148 ! response to vitamin GO:0033273 29 20 0,000 0,04041092 0,0625893 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04041092 0,06254718 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04041092 0,06250512 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04041092 0,06246311 ! spinal cord development GO:0021510 31 20 0,000 0,04041092 0,06242116 ! response to ethanol GO:0045471 37 20 0,000 0,04041092 0,06237927 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04041092 0,06233743 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,04041092 0,06229565 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04041092 0,06225393 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04041092 0,06221226 ! chromosome condensation GO:0030261 31 20 0,000 0,04041092 0,06217064 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04041092 0,06212909 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,04041092 0,06208758 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04041092 0,06204614 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04041092 0,06200475 ! pallium development GO:0021543 38 20 0,000 0,04041092 0,06196341 ! DNA modification GO:0006304 28 20 0,000 0,04041092 0,06192213 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04041092 0,0618809 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04041092 0,06183973 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04041092 0,06179861 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04041092 0,06175755 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04041092 0,06171654 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,04041092 0,06167559 ! collagen catabolic process GO:0030574 25 20 0,000 0,04041092 0,06163469 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04041092 0,06159385 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04041092 0,06155306 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04041092 0,06151232 ! actin filament-based movement GO:0030048 34 20 0,000 0,04041092 0,06147164 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04238923 0,06443835 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04238923 0,06439579 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04238923 0,06435328 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04238923 0,06431083 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,04238923 0,06426844 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04238923 0,0642261 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04238923 0,06418382 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04238923 0,06414159 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04238923 0,06409942 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04238923 0,06405731 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04238923 0,06401525 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04238923 0,06397324 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04238923 0,06393129 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04238923 0,0638894 ! vesicle docking GO:0048278 27 21 0,000 0,04238923 0,06384756 ! phototransduction GO:0007602 25 21 0,000 0,04238923 0,06380577 ! dendrite development GO:0016358 35 21 0,000 0,04238923 0,06376404 ! visual behavior GO:0007632 39 21 0,000 0,04238923 0,06372237 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04238923 0,06368075 ! ovarian follicle development GO:0001541 30 21 0,000 0,04238923 0,06363918 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04238923 0,06359767 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04238923 0,06355621 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04238923 0,0635148 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04238923 0,06347345 ! cell aging GO:0007569 32 21 0,000 0,04238923 0,06343215 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04238923 0,06339091 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04238923 0,06334972 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04238923 0,06330858 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04238923 0,0632675 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04238923 0,06322647 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04238923 0,0631855 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04238923 0,06314457 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04238923 0,0631037 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04238923 0,06306289 ! fatty acid transport GO:0015908 30 21 0,000 0,04238923 0,06302212 ! immunoglobulin production GO:0002377 33 21 0,000 0,04238923 0,06298141 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04238923 0,06294075 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,04238923 0,06290014 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04238923 0,06285959 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04238923 0,06281909 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,04238923 0,06277864 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04238923 0,06273824 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04238923 0,06269789 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04238923 0,0626576 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04238923 0,06261735 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04238923 0,06257716 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04238923 0,06253702 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04238923 0,06249694 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04238923 0,0624569 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04238923 0,06241691 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04238923 0,06237698 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04436357 0,06524054 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04436357 0,06519885 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,04436357 0,06515722 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04436357 0,06511564 ! viral genome replication GO:0019079 29 22 0,000 0,04436357 0,06507411 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04436357 0,06503264 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04436357 0,06499121 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04436357 0,06494985 ! molting cycle process GO:0022404 40 22 0,000 0,04436357 0,06490853 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04436357 0,06486726 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04436357 0,06482605 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04436357 0,06478489 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04436357 0,06474379 ! vasculogenesis GO:0001570 33 22 0,000 0,04436357 0,06470273 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04436357 0,06466173 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04436357 0,06462078 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04436357 0,06457988 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04436357 0,06453903 ! lysosome organization GO:0007040 37 22 0,000 0,04436357 0,06449823 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04436357 0,06445749 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04436357 0,0644168 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04436357 0,06437616 ! regulation of behavior GO:0050795 38 22 0,000 0,04436357 0,06433557 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04436357 0,06429503 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04436357 0,06425454 ! membrane depolarization GO:0051899 35 22 0,000 0,04436357 0,0642141 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04436357 0,06417372 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04436357 0,06413338 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,04436357 0,0640931 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04436357 0,06405286 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04436357 0,06401268 ! blastocyst development GO:0001824 37 22 0,000 0,04436357 0,06397254 ! neural tube closure GO:0001843 33 22 0,000 0,04436357 0,06393246 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04436357 0,06389243 ! protein tetramerization GO:0051262 39 22 0,000 0,04436357 0,06385245 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04633395 0,06664671 ! neuron fate commitment GO:0048663 32 23 0,000 0,04633395 0,06660506 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04633395 0,06656346 ! myelination GO:0042552 35 23 0,000 0,04633395 0,0665219 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04633395 0,06648041 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04633395 0,06643896 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,04633395 0,06639756 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04633395 0,06635622 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04633395 0,06631493 ! vesicle targeting GO:0006903 32 23 0,000 0,04633395 0,06627369 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04633395 0,0662325 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04633395 0,06619136 ! osteoblast differentiation GO:0001649 40 23 0,000 0,04633395 0,06615027 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04633395 0,06610924 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04633395 0,06606825 ! interaction with host GO:0051701 37 23 0,000 0,04633395 0,06602732 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04633395 0,06598643 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04633395 0,0659456 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04633395 0,06590482 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04633395 0,06586409 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,04633395 0,0658234 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04633395 0,06578277 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04633395 0,06574219 ! cell fate determination GO:0001709 45 23 0,000 0,04633395 0,06570166 ! pentose metabolic process GO:0019321 31 23 0,000 0,04633395 0,06566118 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04633395 0,06562075 ! spermatid development GO:0007286 33 23 0,000 0,04633395 0,06558036 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04633395 0,06554003 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04633395 0,06549975 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04633395 0,06545952 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04633395 0,06541933 ! telomere organization GO:0032200 32 23 0,000 0,04633395 0,0653792 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04633395 0,06533911 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04633395 0,06529908 ! regulation of amine transport GO:0051952 38 23 0,000 0,04633395 0,06525909 ! liver development GO:0001889 40 23 0,000 0,04633395 0,06521915 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04830039 0,0679455 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04830039 0,06790397 ! initiation of viral infection GO:0019059 42 24 0,000 0,04830039 0,06786249 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04830039 0,06782106 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04830039 0,06777968 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04830039 0,06773835 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04830039 0,06769707 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04830039 0,06765584 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04830039 0,06761466 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04830039 0,06757353 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04830039 0,06753246 ! vacuole organization GO:0007033 39 24 0,000 0,04830039 0,06749143 ! receptor metabolic process GO:0043112 37 24 0,000 0,04830039 0,06745045 ! neural crest cell development GO:0014032 39 24 0,000 0,04830039 0,06740952 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04830039 0,06736864 ! primary neural tube formation GO:0014020 35 24 0,000 0,04830039 0,06732781 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04830039 0,06728703 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04830039 0,0672463 ! base-excision repair GO:0006284 31 24 0,000 0,04830039 0,06720562 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04830039 0,06716499 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04830039 0,06712441 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04830039 0,06708387 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04830039 0,06704339 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04830039 0,06700295 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04830039 0,06696256 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04830039 0,06692222 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05026288 0,06959941 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05026288 0,06955753 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05026288 0,06951571 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05026288 0,06947393 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05026288 0,06943221 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05026288 0,06939053 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,05026288 0,0693489 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,05026288 0,06930733 ! peptide transport GO:0015833 43 25 0,000 0,05026288 0,0692658 ! male gonad development GO:0008584 33 25 0,000 0,05026288 0,06922432 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05026288 0,0691829 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,05026288 0,06914152 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05026288 0,06910019 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05026288 0,06905891 ! phospholipid transport GO:0015914 35 25 0,000 0,05026288 0,06901768 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05026288 0,0689765 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,05026288 0,06893537 ! detection of light stimulus GO:0009583 30 25 0,000 0,05026288 0,06889429 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05026288 0,06885326 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05026288 0,06881228 ! leukocyte proliferation GO:0070661 39 25 0,000 0,05026288 0,06877134 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05026288 0,06873045 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05222144 0,07136619 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05222144 0,07132381 ! translational initiation GO:0006413 43 26 0,000 0,05222144 0,07128149 ! regulation of pH GO:0006885 36 26 0,000 0,05222144 0,07123921 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,05222144 0,07119698 ! circadian rhythm GO:0007623 42 26 0,000 0,05222144 0,0711548 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05222144 0,07111267 ! post-embryonic development GO:0009791 42 26 0,000 0,05222144 0,07107059 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05222144 0,07102857 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,05222144 0,07098659 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,05222144 0,07094466 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05222144 0,07090278 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05222144 0,07086095 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,05222144 0,07081917 ! regulation of coagulation GO:0050818 39 26 0,000 0,05222144 0,07077743 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05417607 0,07338337 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05417607 0,07334017 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05417607 0,07329703 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05417607 0,07325394 ! membrane docking GO:0022406 39 27 0,000 0,05417607 0,0732109 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05417607 0,07316791 ! catechol metabolic process GO:0009712 43 27 0,000 0,05417607 0,07312497 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05417607 0,07308208 ! acute-phase response GO:0006953 42 27 0,000 0,05417607 0,07303925 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05417607 0,07299646 ! myofibril assembly GO:0030239 36 27 0,000 0,05417607 0,07295372 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05417607 0,07291103 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05417607 0,07286839 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05417607 0,07282581 ! natural killer cell activation GO:0030101 35 27 0,000 0,05417607 0,07278327 ! lipid oxidation GO:0034440 38 27 0,000 0,05417607 0,07274078 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05417607 0,07269834 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05417607 0,07265595 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05417607 0,07261361 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05417607 0,07257132 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05417607 0,07252908 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05417607 0,07248688 ! gene silencing GO:0016458 41 27 0,000 0,05417607 0,07244474 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05612678 0,07500964 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05612678 0,07496608 ! phenol metabolic process GO:0018958 44 28 0,000 0,05612678 0,07492257 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05612678 0,07487911 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05612678 0,0748357 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05612678 0,07479235 ! cell junction assembly GO:0034329 56 28 0,000 0,05612678 0,07474904 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05612678 0,07470578 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05612678 0,07466257 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05612678 0,07461942 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05612678 0,07457631 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05612678 0,07453325 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05612678 0,07449024 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05612678 0,07444728 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05612678 0,07440437 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05612678 0,07436151 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05612678 0,0743187 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05612678 0,07427594 ! mesoderm formation GO:0001707 46 28 0,000 0,05612678 0,07423323 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05612678 0,07419057 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05612678 0,07414796 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05612678 0,07410539 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05612678 0,07406287 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05612678 0,07402041 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05612678 0,07397799 ! neural tube formation GO:0001841 41 28 0,000 0,05612678 0,07393562 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05612678 0,0738933 ! placenta development GO:0001890 37 28 0,000 0,05612678 0,07385102 ! regulation of B cell activation GO:0050864 42 28 0,000 0,05612678 0,0738088 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05807358 0,07632527 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05807358 0,07628168 ! ovulation cycle process GO:0022602 41 29 0,000 0,05807358 0,07623814 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05807358 0,07619465 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05807358 0,07615121 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05807358 0,07610782 ! mismatch repair GO:0006298 34 29 0,000 0,05807358 0,07606448 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05807358 0,07602119 ! muscle cell development GO:0055001 38 29 0,000 0,05807358 0,07597795 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05807358 0,07593475 ! telencephalon development GO:0021537 52 29 0,000 0,05807358 0,07589161 ! eye morphogenesis GO:0048592 51 29 0,000 0,05807358 0,07584851 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05807358 0,07580546 ! tissue homeostasis GO:0001894 42 29 0,000 0,05807358 0,07576247 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06001647 0,07825277 ! collagen metabolic process GO:0032963 40 30 0,000 0,06001647 0,07820843 ! organic anion transport GO:0015711 51 30 0,000 0,06001647 0,07816415 ! cholesterol transport GO:0030301 46 30 0,000 0,06001647 0,07811991 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06001647 0,07807573 ! spliceosome assembly GO:0000245 49 30 0,000 0,06001647 0,07803159 ! spindle organization GO:0007051 37 30 0,000 0,06001647 0,07798751 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06001647 0,07794347 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06001647 0,07789948 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06001647 0,07785555 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06001647 0,07781166 ! ovulation cycle GO:0042698 43 30 0,000 0,06001647 0,07776782 ! hindbrain development GO:0030902 45 30 0,000 0,06001647 0,07772404 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06001647 0,0776803 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06001647 0,07763661 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06001647 0,07759297 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06001647 0,07754937 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06001647 0,07750583 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06001647 0,07746234 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06195547 0,07992013 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06195547 0,07987533 ! mammary gland development GO:0030879 57 31 0,000 0,06195547 0,07983058 ! glial cell differentiation GO:0010001 55 31 0,000 0,06195547 0,07978588 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,06195547 0,07974123 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06195547 0,07969664 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06195547 0,07965209 ! odontogenesis GO:0042476 50 31 0,000 0,06195547 0,07960759 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06195547 0,07956314 ! segmentation GO:0035282 41 31 0,000 0,06195547 0,07951874 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06195547 0,07947439 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,06195547 0,07943009 ! metanephros development GO:0001656 58 31 0,000 0,06195547 0,07938584 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06195547 0,07934164 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06195547 0,07929749 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,06195547 0,07925338 ! cell fate specification GO:0001708 37 31 0,000 0,06195547 0,07920933 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06195547 0,07916532 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06195547 0,07912137 ! RNA modification GO:0009451 40 31 0,000 0,06195547 0,07907746 ! regulation of muscle development GO:0048634 48 32 0,000 0,06389058 0,08150213 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06389058 0,08145695 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06389058 0,08141182 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06389058 0,08136674 ! meiosis I GO:0007127 52 32 0,000 0,06389058 0,08132171 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06389058 0,08127674 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06389058 0,08123181 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,06389058 0,08118693 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06389058 0,0811421 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06389058 0,08109732 ! regulation of protein stability GO:0031647 48 32 0,000 0,06389058 0,08105259 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,06389058 0,0810079 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06389058 0,08096327 ! cytokine production GO:0001816 44 32 0,000 0,06389058 0,08091869 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06389058 0,08087415 ! vesicle localization GO:0051648 47 32 0,000 0,06389058 0,08082967 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06582181 0,08322714 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06582181 0,08318141 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06582181 0,08313573 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06582181 0,0830901 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06582181 0,08304452 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06582181 0,08299899 ! ear morphogenesis GO:0042471 42 33 0,000 0,06582181 0,08295351 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06582181 0,08290808 ! cell junction organization GO:0034330 63 33 0,000 0,06582181 0,08286271 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06582181 0,08281738 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06582181 0,0827721 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06582181 0,08272687 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06582181 0,08268168 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06582181 0,08263655 ! female gonad development GO:0008585 49 33 0,000 0,06582181 0,08259147 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06582181 0,08254644 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06582181 0,08250145 ! lipid homeostasis GO:0055088 55 33 0,000 0,06582181 0,08245652 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06582181 0,08241163 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06582181 0,08236679 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06582181 0,082322 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06582181 0,08227726 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,06582181 0,08223257 ! cytokinesis GO:0000910 52 33 0,000 0,06582181 0,08218793 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06582181 0,08214333 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06774916 0,08450275 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06774916 0,08445695 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06774916 0,0844112 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06774916 0,0843655 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,06774916 0,08431985 ! feeding behavior GO:0007631 45 34 0,000 0,06774916 0,08427425 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06774916 0,08422869 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06774916 0,08418319 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06774916 0,08413773 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06774916 0,08409233 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06774916 0,08404697 ! neuron migration GO:0001764 46 34 0,000 0,06774916 0,08400166 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,06774916 0,0839564 ! female gamete generation GO:0007292 43 34 0,000 0,06774916 0,08391119 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06774916 0,08386603 ! aerobic respiration GO:0009060 47 34 0,000 0,06774916 0,08382091 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06774916 0,08377585 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,06774916 0,08373083 ! embryonic organ development GO:0048568 45 34 0,000 0,06774916 0,08368586 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06774916 0,08364094 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06967265 0,08596948 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06967265 0,08592338 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,06967265 0,08587733 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06967265 0,08583134 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06967265 0,08578539 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,06967265 0,08573949 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06967265 0,08569364 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06967265 0,08564784 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06967265 0,08560209 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06967265 0,08555638 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06967265 0,08551073 ! glycogen metabolic process GO:0005977 48 35 0,000 0,06967265 0,08546512 ! pigment metabolic process GO:0042440 61 35 0,000 0,06967265 0,08541956 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,06967265 0,08537406 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,06967265 0,0853286 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,07159228 0,08763292 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,07159228 0,0875863 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,07159228 0,08753974 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,07159228 0,08749323 ! negative regulation of binding GO:0051100 58 36 0,000 0,07159228 0,08744676 ! organic ether metabolic process GO:0018904 46 36 0,000 0,07159228 0,08740035 ! tissue remodeling GO:0048771 62 36 0,000 0,07159228 0,08735398 ! neural tube development GO:0021915 50 36 0,000 0,07159228 0,08730766 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,07159228 0,08726139 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,07159228 0,08721518 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,07159228 0,08716901 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,07159228 0,08712288 ! glucan metabolic process GO:0044042 49 36 0,000 0,07159228 0,08707681 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,07350806 0,0893597 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,07350806 0,08931249 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,07350806 0,08926533 ! learning GO:0007612 67 37 0,000 0,07350806 0,08921823 ! ion transmembrane transport GO:0034220 56 37 0,000 0,07350806 0,08917117 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,07350806 0,08912417 ! regulation of protein secretion GO:0050708 51 37 0,000 0,07350806 0,08907721 ! amino acid activation GO:0043038 52 37 0,000 0,07350806 0,0890303 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,07350806 0,08898344 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,07542 0,09124987 ! gliogenesis GO:0042063 71 38 0,000 0,07542 0,09120189 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,07542 0,09115396 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,07542 0,09110609 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,07542 0,09105826 ! phagocytosis GO:0006909 60 38 0,000 0,07542 0,09101049 ! mesenchymal cell development GO:0014031 64 38 0,000 0,07542 0,09096277 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,07542 0,09091509 ! maintenance of location in cell GO:0051651 69 38 0,000 0,07542 0,09086747 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,0773281 0,0931176 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,0773281 0,09306888 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,0773281 0,0930202 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,0773281 0,09297157 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,0773281 0,092923 ! male sex differentiation GO:0046661 53 39 0,000 0,0773281 0,09287448 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,0773281 0,092826 ! chromatin remodeling GO:0006338 68 39 0,000 0,0773281 0,09277758 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,0773281 0,09272921 ! JNK cascade GO:0007254 54 39 0,000 0,0773281 0,09268089 ! developmental growth GO:0048589 62 39 0,000 0,0773281 0,09263262 ! cell growth GO:0016049 61 39 0,000 0,0773281 0,09258439 ! synapse organization GO:0050808 55 39 0,000 0,0773281 0,09253622 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07923237 0,0947657 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07923237 0,09471645 ! regulation of tube size GO:0035150 60 40 0,000 0,07923237 0,09466724 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07923237 0,09461809 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07923237 0,09456899 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07923237 0,09451994 ! peptide metabolic process GO:0006518 56 40 0,000 0,07923237 0,09447094 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,07923237 0,09442199 ! inner ear development GO:0048839 57 40 0,000 0,07923237 0,09437309 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07923237 0,09432425 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07923237 0,09427545 ! double-strand break repair GO:0006302 67 40 0,000 0,07923237 0,0942267 ! B cell differentiation GO:0030183 62 40 0,000 0,07923237 0,09417801 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,07923237 0,09412936 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07923237 0,09408077 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07923237 0,09403222 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07923237 0,09398373 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,08113282 0,09618839 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,08113282 0,09613883 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,08113282 0,09608933 ! glucose transport GO:0015758 52 41 0,000 0,08113282 0,09603988 ! endosome transport GO:0016197 71 41 0,000 0,08113282 0,09599047 ! striated muscle contraction GO:0006941 62 41 0,000 0,08113282 0,09594112 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,08113282 0,09589182 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,08113282 0,09584257 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,08113282 0,09579337 ! biopolymer methylation GO:0043414 62 41 0,000 0,08113282 0,09574422 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,08113282 0,09569512 ! mitochondrial transport GO:0006839 60 42 0,000 0,08302945 0,09788198 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,08302945 0,09783183 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,08302945 0,09778174 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,08302945 0,0977317 ! cellular component disassembly GO:0022411 64 42 0,000 0,08302945 0,09768171 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08302945 0,09763177 ! hexose transport GO:0008645 54 42 0,000 0,08302945 0,09758188 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08302945 0,09753204 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,08302945 0,09748226 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08302945 0,09743252 ! excretion GO:0007588 63 42 0,000 0,08302945 0,09738283 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08302945 0,0973332 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08302945 0,09728362 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08302945 0,09723408 ! regulation of cell shape GO:0008360 78 42 0,000 0,08302945 0,0971846 ! positive regulation of binding GO:0051099 59 43 0,000 0,08492228 0,09934957 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08492228 0,09929906 ! leukocyte migration GO:0050900 60 43 0,000 0,08492228 0,0992486 ! neuromuscular process GO:0050905 79 43 0,000 0,08492228 0,09919819 ! activation of caspase activity GO:0006919 65 43 0,000 0,08492228 0,09914784 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08492228 0,09909754 ! tRNA processing GO:0008033 49 43 0,000 0,08492228 0,09904728 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,08492228 0,09899708 ! vesicle organization GO:0016050 79 43 0,000 0,08492228 0,09894693 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08492228 0,09889683 ! methylation GO:0032259 64 43 0,000 0,08492228 0,09884678 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,08681131 0,10099444 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,08681131 0,10094338 ! glycolysis GO:0006096 53 44 0,000 0,08681131 0,10089238 ! regulation of action potential GO:0001508 71 44 0,000 0,08681131 0,10084142 ! regulation of ion transport GO:0043269 57 44 0,000 0,08681131 0,10079052 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,08681131 0,10073966 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,08681131 0,10068886 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,08681131 0,10063811 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,08681131 0,10058741 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,08681131 0,10053677 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,08681131 0,10048617 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,08681131 0,10043562 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,08681131 0,10038513 ! RNA catabolic process GO:0006401 64 45 0,000 0,08869655 0,1025136 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08869655 0,10246211 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08869655 0,10241067 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08869655 0,10235929 ! cell recognition GO:0008037 58 45 0,000 0,08869655 0,10230796 ! cell maturation GO:0048469 60 45 0,000 0,08869655 0,10225667 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,08869655 0,10220544 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,090578 0,10432119 ! cell redox homeostasis GO:0045454 63 46 0,000 0,090578 0,10426897 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,090578 0,10421681 ! regulation of ossification GO:0030278 71 46 0,000 0,090578 0,10416471 ! histone modification GO:0016570 68 46 0,000 0,090578 0,10411265 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,090578 0,10406064 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09245568 0,10616479 ! viral infectious cycle GO:0019058 71 47 0,000 0,09245568 0,10611181 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,09245568 0,10605889 ! endocrine system development GO:0035270 83 47 0,000 0,09245568 0,10600602 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09245568 0,1059532 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,09245568 0,10590043 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09245568 0,10584772 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,09245568 0,10579506 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09245568 0,10574245 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,09245568 0,1056899 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,09245568 0,10563739 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,09245568 0,10558494 ! chloride transport GO:0006821 67 48 0,000 0,09432959 0,10767149 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,09432959 0,10761808 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,09432959 0,10756473 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,09432959 0,10751143 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,09432959 0,10745818 ! gastrulation GO:0007369 73 48 0,000 0,09432959 0,10740498 ! heart morphogenesis GO:0003007 65 48 0,000 0,09432959 0,10735184 ! regulation of DNA replication GO:0006275 75 48 0,000 0,09432959 0,10729874 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,09432959 0,1072457 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,09432959 0,10719272 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,09432959 0,10713978 ! regulation of endocytosis GO:0030100 63 48 0,000 0,09432959 0,1070869 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,09432959 0,10703407 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,09432959 0,10698129 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,09619974 0,10904849 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,09619974 0,10899478 ! sensory perception of smell GO:0007608 61 49 0,000 0,09619974 0,10894111 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,09619974 0,1088875 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,09619974 0,10883394 ! RNA elongation GO:0006354 62 49 0,000 0,09619974 0,10878043 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,09619974 0,10872698 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,09619974 0,10867357 ! germ cell development GO:0007281 68 49 0,000 0,09619974 0,10862022 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,09619974 0,10856693 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,09619974 0,10851368 ! cartilage development GO:0051216 70 49 0,000 0,09619974 0,10846049 ! maintenance of location GO:0051235 84 49 0,000 0,09619974 0,10840735 ! regulation of actin filament length GO:0030832 72 50 0,000 0,09806613 0,11045646 ! ear development GO:0043583 72 50 0,000 0,09806613 0,1104024 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,09806613 0,11034838 ! membrane fusion GO:0006944 80 50 0,000 0,09806613 0,11029442 ! lipid modification GO:0030258 73 50 0,000 0,09806613 0,11024052 ! positive regulation of growth GO:0045927 67 50 0,000 0,09806613 0,11018666 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09806613 0,11013286 ! proton transport GO:0015992 75 50 0,000 0,09806613 0,11007911 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09806613 0,11002541 ! positive regulation of secretion GO:0051047 71 51 0,000 0,09992877 0,11206055 ! hydrogen transport GO:0006818 77 51 0,000 0,09992877 0,11200594 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,09992877 0,11195138 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,09992877 0,11189687 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,09992877 0,11184242 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,09992877 0,11178803 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,09992877 0,11173368 ! adult behavior GO:0030534 80 51 0,000 0,09992877 0,11167939 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,09992877 0,11162515 ! transition metal ion transport GO:0000041 74 52 0,000 0,10178768 0,11364644 ! regulation of cellular component size GO:0032535 74 52 0,000 0,10178768 0,1135913 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,10178768 0,11353621 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,10178768 0,11348117 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,10178768 0,11342619 ! establishment of organelle localization GO:0051656 85 52 0,000 0,10178768 0,11337126 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,10364285 0,11538168 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,10364285 0,11532586 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,10364285 0,11527009 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,10364285 0,11521438 ! kidney development GO:0001822 90 53 0,000 0,10364285 0,11515872 ! single fertilization GO:0007338 59 53 0,000 0,10364285 0,11510312 ! cell projection assembly GO:0030031 76 53 0,000 0,10364285 0,11504757 ! amino acid transport GO:0006865 84 54 0,000 0,1054943 0,11704625 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,1054943 0,11698982 ! regulation of mitosis GO:0007088 84 54 0,000 0,1054943 0,11693344 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,1054943 0,11687711 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,1054943 0,11682084 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,1054943 0,11676462 ! DNA catabolic process GO:0006308 67 54 0,000 0,1054943 0,11670846 ! detection of external stimulus GO:0009581 66 54 0,000 0,1054943 0,11665235 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,1054943 0,11659629 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,1054943 0,11654029 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,1054943 0,11648434 ! exocytosis GO:0006887 74 55 0,000 0,10734202 0,11846769 ! mesoderm development GO:0007498 76 55 0,000 0,10734202 0,11841087 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,10734202 0,1183541 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,10734202 0,11829739 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,10918604 0,12027198 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,10918604 0,12021441 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10918604 0,12015689 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,10918604 0,12009942 ! carbohydrate transport GO:0008643 74 57 0,000 0,11102636 0,1220653 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,11102636 0,12200698 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,11102636 0,12194872 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,11102636 0,12189051 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,11102636 0,12183236 ! camera-type eye development GO:0043010 88 57 0,000 0,11102636 0,12177426 ! secondary metabolic process GO:0019748 84 57 0,000 0,11102636 0,12171621 ! developmental maturation GO:0021700 75 57 0,000 0,11102636 0,12165823 ! gonad development GO:0008406 79 57 0,000 0,11102636 0,12160029 ! viral reproductive process GO:0022415 87 58 0,000 0,11286297 0,12355299 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,11286297 0,12349421 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,11286297 0,12343549 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,11286297 0,12337682 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1146959 0,12532094 ! activation of MAPK activity GO:0000187 84 59 0,000 0,1146959 0,12526143 ! lung development GO:0030324 94 59 0,000 0,1146959 0,12520198 ! actin filament organization GO:0007015 95 59 0,000 0,1146959 0,12514259 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1146959 0,12508325 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,1146959 0,12502397 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,11652515 0,12695776 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,11652515 0,12689765 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,11652515 0,12683759 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,11652515 0,12677759 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,11652515 0,12671765 ! regulation of heart contraction GO:0008016 91 60 0,000 0,11652515 0,12665777 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,11652515 0,12659794 ! fertilization GO:0009566 68 60 0,000 0,11652515 0,12653817 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,11652515 0,12647845 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,11835072 0,12839936 ! meiosis GO:0007126 96 61 0,000 0,11835072 0,12833882 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,11835072 0,12827834 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,11835072 0,12821792 ! urogenital system development GO:0001655 101 61 0,000 0,11835072 0,12815756 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,11835072 0,12809725 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,11835072 0,12803699 ! extracellular matrix organization GO:0030198 103 61 0,000 0,11835072 0,1279768 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,11835072 0,12791666 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,12017262 0,12982481 ! neurotransmitter transport GO:0006836 81 62 0,000 0,12017262 0,12976386 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,12017262 0,12970297 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,12017262 0,12964213 ! respiratory tube development GO:0030323 99 62 0,000 0,12017262 0,12958135 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,12017262 0,12952063 ! meiotic cell cycle GO:0051321 97 62 0,000 0,12017262 0,12945996 ! organelle localization GO:0051640 96 62 0,000 0,12017262 0,12939936 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,12199086 0,13129573 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,12199086 0,13123432 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,12199086 0,13117297 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,12199086 0,13111167 ! viral reproduction GO:0016032 92 63 0,000 0,12199086 0,13105044 ! regulation of lipase activity GO:0060191 109 63 0,000 0,12199086 0,13098925 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,12380545 0,13287566 ! negative regulation of cell size GO:0045792 108 64 0,000 0,12380545 0,13281368 ! appendage morphogenesis GO:0035107 93 64 0,000 0,12380545 0,13275177 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,12380545 0,13268991 ! hexose catabolic process GO:0019320 82 64 0,000 0,12380545 0,1326281 ! respiratory system development GO:0060541 100 64 0,000 0,12380545 0,13256636 ! adaptive immune response GO:0002250 94 64 0,000 0,12380545 0,13250467 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,12561639 0,13438033 ! regulation of caspase activity GO:0043281 97 65 0,000 0,12561639 0,13431786 ! appendage development GO:0048736 94 65 0,000 0,12561639 0,13425544 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,12561639 0,13419308 ! defense response to bacterium GO:0042742 73 65 0,000 0,12561639 0,13413078 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,12561639 0,13406854 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,12561639 0,13400636 ! activation of immune response GO:0002253 83 65 0,000 0,12561639 0,13394423 ! protein oligomerization GO:0051259 100 65 0,000 0,12561639 0,13388216 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,1274237 0,13574549 ! antigen processing and presentation GO:0019882 96 66 0,000 0,1274237 0,13568264 ! axon guidance GO:0007411 99 66 0,000 0,1274237 0,13561985 ! regulation of immune effector process GO:0002697 101 66 0,000 0,1274237 0,13555713 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,12922737 0,13741237 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,12922737 0,13734887 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,12922737 0,13728543 ! acute inflammatory response GO:0002526 92 68 0,000 0,13102742 0,13913345 ! learning or memory GO:0007611 123 68 0,000 0,13102742 0,13906925 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,13102742 0,1390051 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,13102742 0,13894101 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,13102742 0,13887699 ! rhythmic process GO:0048511 105 68 0,000 0,13102742 0,13881302 ! inorganic anion transport GO:0015698 93 68 0,000 0,13102742 0,13874911 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,13282385 0,14058667 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,13282385 0,14052201 ! response to drug GO:0042493 108 69 0,000 0,13282385 0,1404574 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,13461666 0,14228783 ! humoral immune response GO:0006959 86 70 0,000 0,13461666 0,14222247 ! amine transport GO:0015837 101 70 0,000 0,13461666 0,14215717 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,13461666 0,14209193 ! regulation of catabolic process GO:0009894 106 70 0,000 0,13461666 0,14202675 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,13640588 0,14384847 ! muscle cell differentiation GO:0042692 104 71 0,000 0,13640588 0,14378255 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,13640588 0,14371668 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,13640588 0,14365088 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,13640588 0,14358513 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,13640588 0,14351945 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,1381915 0,14533171 ! response to hypoxia GO:0001666 132 72 0,000 0,1381915 0,14526528 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,1381915 0,14519892 ! negative regulation of transport GO:0051051 116 73 0,000 0,13997352 0,14700416 ! regulation of blood pressure GO:0008217 107 73 0,000 0,13997352 0,14693706 ! tube morphogenesis GO:0035239 118 73 0,000 0,13997352 0,14687003 ! mitochondrion organization GO:0007005 104 73 0,000 0,13997352 0,14680306 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,13997352 0,14673615 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,13997352 0,1466693 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,14175197 0,14846518 ! response to oxygen levels GO:0070482 137 74 0,000 0,14175197 0,1483976 ! digestion GO:0007586 97 74 0,000 0,14175197 0,14833009 ! protein import into nucleus GO:0006606 118 74 0,000 0,14175197 0,14826263 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,14175197 0,14819524 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,14175197 0,14812791 ! blood coagulation GO:0007596 116 75 0,000 0,14352684 0,1499145 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,14352684 0,14984645 ! response to nutrient GO:0007584 104 75 0,000 0,14352684 0,14977846 ! nuclear import GO:0051170 121 75 0,000 0,14352684 0,14971053 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,14352684 0,14964267 ! amine biosynthetic process GO:0009309 97 76 0,000 0,14529814 0,15142081 ! tRNA metabolic process GO:0006399 95 76 0,000 0,14529814 0,15135223 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,14529814 0,15128371 ! regulation of protein transport GO:0051223 114 76 0,000 0,14529814 0,15121526 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,14706588 0,15298576 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,14706588 0,1529166 ! regulation of DNA binding GO:0051101 119 77 0,000 0,14706588 0,1528475 ! gland development GO:0048732 148 77 0,000 0,14706588 0,15277846 ! sex differentiation GO:0007548 105 77 0,000 0,14706588 0,15270949 ! protein ubiquitination GO:0016567 125 77 0,000 0,14706588 0,15264058 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,14706588 0,15257173 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,14706588 0,15250294 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,14883006 0,1542628 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,14883006 0,15419331 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1505907 0,15594714 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1505907 0,15587696 ! T cell activation GO:0042110 134 79 0,000 0,1505907 0,15580684 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1505907 0,15573678 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1505907 0,15566679 ! chromatin assembly GO:0031497 102 80 0,000 0,15234779 0,15741237 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,15234779 0,15734168 ! forebrain development GO:0030900 131 80 0,000 0,15234779 0,15727106 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,15410136 0,15900992 ! hemostasis GO:0007599 125 81 0,000 0,15410136 0,15893862 ! mRNA transport GO:0051028 121 81 0,000 0,15410136 0,15886738 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,15410136 0,1587962 ! regulation of neurological system process GO:0031644 122 81 0,000 0,15410136 0,15872509 ! vitamin metabolic process GO:0006766 103 81 0,000 0,15410136 0,15865404 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,15410136 0,15858305 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,15585139 0,16031225 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,15585139 0,16024059 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,1575979 0,16196389 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,1575979 0,16189155 ! regulation of defense response GO:0031347 117 84 0,000 0,15934091 0,16360897 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,15934091 0,16353596 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,15934091 0,16346302 ! sterol metabolic process GO:0016125 120 84 0,000 0,15934091 0,16339014 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,1610804 0,16510023 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,1610804 0,16502669 ! rRNA metabolic process GO:0016072 107 85 0,000 0,1610804 0,16495322 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,1610804 0,1648798 ! transcription initiation GO:0006352 118 85 0,000 0,1610804 0,16480646 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,1610804 0,16473318 ! regulation of protein localization GO:0032880 132 85 0,000 0,1610804 0,16465997 ! regulation of membrane potential GO:0042391 128 85 0,000 0,1610804 0,16458682 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,1610804 0,16451373 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,1628164 0,16621292 ! nucleosome organization GO:0034728 114 87 0,000 0,1645489 0,16790704 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,1645489 0,16783258 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,1645489 0,16775818 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,1645489 0,16768386 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,1645489 0,16760959 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,1645489 0,1675354 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,16627791 0,16922089 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,16627791 0,16914604 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,16627791 0,16907127 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,16627791 0,16899655 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,16800345 0,17067488 ! reproductive developmental process GO:0003006 127 89 0,000 0,16800345 0,17059953 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,16800345 0,17052424 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,16800345 0,17044902 ! regulation of T cell activation GO:0050863 128 89 0,000 0,16800345 0,17037387 ! leukocyte differentiation GO:0002521 143 90 0,000 0,16972552 0,17204438 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,16972552 0,17196859 ! hormone metabolic process GO:0042445 121 90 0,000 0,16972552 0,17189286 ! ATP metabolic process GO:0046034 137 91 0,000 0,17144412 0,17355698 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,17315926 0,17521614 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,17315926 0,17513909 ! cell fate commitment GO:0045165 141 92 0,000 0,17315926 0,17506211 ! positive regulation of immune response GO:0050778 121 92 0,000 0,17315926 0,17498519 ! DNA recombination GO:0006310 146 92 0,000 0,17315926 0,17490834 ! sulfur metabolic process GO:0006790 118 92 0,000 0,17315926 0,17483156 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,17487095 0,17648231 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,17487095 0,1764049 ! electron transport chain GO:0022900 123 94 0,000 0,17657919 0,17805004 ! response to oxidative stress GO:0006979 141 94 0,000 0,17657919 0,17797201 ! regulation of binding GO:0051098 151 95 0,000 0,17828399 0,17961156 ! angiogenesis GO:0001525 149 95 0,000 0,17828399 0,17953292 ! carboxylic acid transport GO:0046942 147 95 0,000 0,17828399 0,17945435 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,17998537 0,18108764 ! in utero embryonic development GO:0001701 147 96 0,000 0,17998537 0,18100846 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,17998537 0,18092935 ! protein maturation GO:0051604 129 96 0,000 0,17998537 0,1808503 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,18168332 0,18247669 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,18168332 0,18239704 ! calcium ion transport GO:0006816 167 99 0,000 0,18506896 0,18571493 ! extracellular structure organization GO:0043062 156 99 0,000 0,18506896 0,18563394 ! protein import GO:0017038 156 99 0,000 0,18506896 0,18555301 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,18675668 0,18716355 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,18675668 0,18708204 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,18675668 0,18700059 ! divalent metal ion transport GO:0070838 171 100 0,000 0,18675668 0,18691921 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,18675668 0,18683791 ! protein localization in organelle GO:0033365 161 100 0,000 0,18675668 0,18675668