pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3796-4-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 3,791E-08 9,121E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 1,074E-06 1,293E-03 ! fructose metabolic process GO:0006000 25 16 2,000 2,097E-06 1,682E-03 ! alditol metabolic process GO:0019400 38 24 2,000 7,511E-06 4,518E-03 ! sperm motility GO:0030317 31 25 2,000 8,526E-06 4,103E-03 ! hexose biosynthetic process GO:0019319 48 32 2,000 1,824E-05 7,315E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 2,48E-05 8,523E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 2,48E-05 7,458E-03 GO:0032862|activation of Rho GTPase activity, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,48E-05 6,629E-03 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 2,614E-05 6,29E-03 ! polyol metabolic process GO:0019751 66 41 2,000 3,881E-05 8,489E-03 ! alcohol biosynthetic process GO:0046165 59 42 2,000 4,175E-05 8,371E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,922E-05 0,01281109 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 6,922E-05 0,01189602 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 8,891E-05 0,01426069 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,11E-04 0,01669474 ! regulation of stress fiber formation GO:0051492 30 10 1,000 1,11E-04 0,0157127 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 1,11E-04 0,01483977 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 1,356E-04 0,01716541 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 1,918E-04 0,02307946 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 2,236E-04 0,02561776 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 2,943E-04 0,03218057 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,943E-04 0,03078142 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 2,943E-04 0,02949886 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,331E-04 0,03206212 ! response to unfolded protein GO:0006986 131 85 2,000 3,424E-04 0,03168088 ! alcohol catabolic process GO:0046164 130 86 2,000 3,543E-04 0,03157491 ! cellular response to unfolded protein GO:0034620 33 19 1,000 4,18E-04 0,03592096 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to protein stimulus GO:0051789 149 91 2,000 4,183E-04 0,03470247 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 4,458E-04 0,03575244 ! negative regulation of translation GO:0017148 29 20 1,000 4,64E-04 0,03601306 ! inactivation of MAPK activity GO:0000188 39 21 1,000 5,123E-04 0,03852084 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 5,123E-04 0,03735354 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,63E-04 0,03983987 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,16E-04 0,04234438 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,16E-04 0,04116815 GO:0010810|regulation of cell-substrate adhesion, ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,289E-04 0,04740016 ! fat cell differentiation GO:0045444 50 27 1,000 8,511E-04 0,05388911 ! negative regulation of protein modification process GO:0031400 60 28 1,000 9,157E-04 0,05648893 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,157E-04 0,05507671 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,825E-04 0,05765501 ! response to heat GO:0009408 50 30 1,000 1,052E-03 0,0602412 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,197E-03 0,06695523 ! regulation of microtubule-based process GO:0032886 78 35 1,000 1,431E-03 0,07825505 ! RNA export from nucleus GO:0006405 56 37 1,000 1,599E-03 0,0854728 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 2,056E-03 0,1075493 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 2,154E-03 0,11028375 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,462E-03 0,12339543 ! response to insulin stimulus GO:0032868 95 46 1,000 2,462E-03 0,12087716 ! response to calcium ion GO:0051592 81 47 1,000 2,569E-03 0,12359907 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,678E-03 0,1263159 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 2,789E-03 0,12902762 ! response to temperature stimulus GO:0009266 76 49 1,000 2,789E-03 0,12659314 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 2,789E-03 0,12424882 ! regulation of translational initiation GO:0006446 82 53 1,000 3,254E-03 0,14236533 ! response to UV GO:0009411 104 53 1,000 3,254E-03 0,13982309 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 3,376E-03 0,14250902 ! aging GO:0007568 103 55 1,000 3,5E-03 0,14518974 ! nuclear export GO:0051168 97 55 1,000 3,5E-03 0,1427289 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 3,754E-03 0,15053555 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 4,287E-03 0,16909048 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 5,148E-03 0,19978232 ! negative regulation of kinase activity GO:0033673 131 68 1,000 5,299E-03 0,20236419 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 5,299E-03 0,19920225 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 5,451E-03 0,20178817 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 5,921E-03 0,21586385 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 5,921E-03 0,21264201 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 5,921E-03 0,20951492 ! negative regulation of transferase activity GO:0051348 140 72 1,000 5,921E-03 0,20647847 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 6,245E-03 0,21464021 ! eye development GO:0001654 143 74 1,000 6,245E-03 0,21161711 ! regulation of actin filament-based process GO:0032970 152 77 1,000 6,744E-03 0,22537671 ! positive regulation of ligase activity GO:0051351 124 77 1,000 6,744E-03 0,22228935 ! negative regulation of organelle organization GO:0010639 161 78 1,000 6,915E-03 0,22482872 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 7,087E-03 0,22736292 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 7,087E-03 0,2243713 ! response to metal ion GO:0010038 140 80 1,000 7,262E-03 0,22690634 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 7,438E-03 0,22943612 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,944E-03 0,24194267 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,944E-03 0,23891839 ! positive regulation of helicase activity GO:0051096 11 5 0,000 7,944E-03 0,23596878 ! neuron fate determination GO:0048664 7 5 0,000 7,944E-03 0,23309111 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,944E-03 0,23028278 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 7,944E-03 0,22754132 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,944E-03 0,22486437 ! polyol transport GO:0015791 12 5 0,000 7,944E-03 0,22224966 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 7,944E-03 0,21969507 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,944E-03 0,21719853 ! response to superoxide GO:0000303 10 5 0,000 7,944E-03 0,2147581 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,944E-03 0,2123719 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 7,944E-03 0,21003814 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 7,944E-03 0,20775512 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,944E-03 0,20552119 ! female meiosis GO:0007143 7 5 0,000 7,944E-03 0,2033348 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,944E-03 0,20119443 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,944E-03 0,19909866 ! cobalt ion transport GO:0006824 11 5 0,000 7,944E-03 0,19704609 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 7,944E-03 0,19503542 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 7,944E-03 0,19306536 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 7,944E-03 0,19113471 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,944E-03 0,18924229 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,944E-03 0,18738697 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 7,944E-03 0,18556768 ! embryonic camera-type eye development GO:0031076 10 5 0,000 7,944E-03 0,18378338 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,944E-03 0,18203306 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 7,944E-03 0,18031576 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 7,944E-03 0,17863057 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,944E-03 0,17697658 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,944E-03 0,17535295 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,944E-03 0,17375883 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 7,944E-03 0,17219343 ! negative chemotaxis GO:0050919 14 5 0,000 7,944E-03 0,17065599 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,944E-03 0,16914576 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,944E-03 0,16766203 ! sensory perception of bitter taste GO:0050913 7 5 0,000 7,944E-03 0,1662041 ! behavioral response to pain GO:0048266 9 5 0,000 7,944E-03 0,1647713 ! clathrin coat assembly GO:0048268 14 5 0,000 7,944E-03 0,163363 ! Notch receptor processing GO:0007220 8 5 0,000 7,944E-03 0,16197857 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,944E-03 0,1606174 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,944E-03 0,15927893 ! micturition GO:0060073 9 5 0,000 7,944E-03 0,15796257 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,944E-03 0,1566678 ! copulation GO:0007620 9 5 0,000 7,944E-03 0,15539407 ! glial cell fate commitment GO:0021781 13 5 0,000 7,944E-03 0,1541409 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,944E-03 0,15290777 ! spermidine metabolic process GO:0008216 7 5 0,000 7,944E-03 0,15169421 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,944E-03 0,15049977 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,944E-03 0,14932399 ! apoptotic cell clearance GO:0043277 20 5 0,000 7,944E-03 0,14816644 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,944E-03 0,1470267 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,944E-03 0,14590436 ! grooming behavior GO:0007625 6 5 0,000 7,944E-03 0,14479902 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,944E-03 0,14371031 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 7,944E-03 0,14263784 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,944E-03 0,14158127 ! response to protozoan GO:0001562 10 5 0,000 7,944E-03 0,14054023 ! positive regulation of glycolysis GO:0045821 14 5 0,000 7,944E-03 0,13951439 ! lymph vessel development GO:0001945 10 5 0,000 7,944E-03 0,13850341 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 7,944E-03 0,13750699 ! endochondral ossification GO:0001958 16 5 0,000 7,944E-03 0,13652479 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,944E-03 0,13555653 ! parathyroid gland development GO:0060017 13 5 0,000 7,944E-03 0,13460191 ! anagen GO:0042640 6 5 0,000 7,944E-03 0,13366064 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,944E-03 0,13273244 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,944E-03 0,13181704 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 7,944E-03 0,13091419 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 7,944E-03 0,13002361 ! dorsal spinal cord development GO:0021516 7 5 0,000 7,944E-03 0,12914507 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 7,944E-03 0,12827833 ! sphingoid catabolic process GO:0046521 6 5 0,000 7,944E-03 0,12742314 ! skeletal myofibril assembly GO:0014866 10 5 0,000 7,944E-03 0,12657928 ! smooth muscle tissue development GO:0048745 28 5 0,000 7,944E-03 0,12574652 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,944E-03 0,12492465 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,944E-03 0,12411345 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,944E-03 0,12331272 ! cardiac muscle fiber development GO:0048739 10 5 0,000 7,944E-03 0,12252225 ! transepithelial chloride transport GO:0030321 9 5 0,000 7,944E-03 0,12174185 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,944E-03 0,12097134 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 7,944E-03 0,12021051 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 7,944E-03 0,11945919 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,944E-03 0,11871721 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,944E-03 0,11798439 ! histidine catabolic process GO:0006548 6 5 0,000 7,944E-03 0,11726056 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 7,944E-03 0,11654556 ! microvillus organization GO:0032528 7 5 0,000 7,944E-03 0,11583922 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 7,944E-03 0,11514139 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,944E-03 0,11445192 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,944E-03 0,11377066 ! tryptophan metabolic process GO:0006568 9 5 0,000 7,944E-03 0,11309746 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 7,944E-03 0,11243218 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,944E-03 0,11177468 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 7,944E-03 0,11112483 ! polyol biosynthetic process GO:0046173 5 5 0,000 7,944E-03 0,11048249 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,944E-03 0,10984753 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,944E-03 0,10921983 ! muscle cell migration GO:0014812 8 5 0,000 7,944E-03 0,10859927 ! mitochondrial fission GO:0000266 8 5 0,000 7,944E-03 0,10798571 ! sister chromatid cohesion GO:0007062 12 5 0,000 7,944E-03 0,10737905 ! mRNA transcription GO:0009299 9 5 0,000 7,944E-03 0,10677917 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 7,944E-03 0,10618595 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 7,944E-03 0,10559929 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 7,944E-03 0,10501907 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,944E-03 0,1044452 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,944E-03 0,10387756 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,944E-03 0,10331606 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,944E-03 0,1027606 ! response to food GO:0032094 6 5 0,000 7,944E-03 0,10221108 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,944E-03 0,1016674 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,944E-03 0,10112948 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 7,944E-03 0,10059722 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,944E-03 0,10007053 ! paraxial mesoderm development GO:0048339 14 5 0,000 7,944E-03 0,09954933 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 7,944E-03 0,09903353 ! forebrain neuron development GO:0021884 13 5 0,000 7,944E-03 0,09852305 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,944E-03 0,0980178 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 7,944E-03 0,09751771 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,944E-03 0,0970227 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,944E-03 0,09653268 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,944E-03 0,09604759 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 7,944E-03 0,09556736 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,944E-03 0,0950919 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 7,944E-03 0,09462114 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 7,944E-03 0,09415503 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,944E-03 0,09369349 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 7,944E-03 0,09323644 ! basic amino acid transport GO:0015802 11 5 0,000 7,944E-03 0,09278384 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,944E-03 0,09233561 ! early endosome to late endosome transport GO:0045022 12 5 0,000 7,944E-03 0,09189169 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,944E-03 0,09145201 ! depyrimidination GO:0045008 10 5 0,000 7,944E-03 0,09101653 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,944E-03 0,09058517 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,944E-03 0,09015788 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,944E-03 0,08973461 ! zinc ion homeostasis GO:0055069 8 5 0,000 7,944E-03 0,08931529 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 7,944E-03 0,08889987 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 7,944E-03 0,08848829 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,944E-03 0,08808051 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,944E-03 0,08767647 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,944E-03 0,08727612 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 7,944E-03 0,08687941 ! peptidyl-arginine modification GO:0018195 9 5 0,000 7,944E-03 0,08648629 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,944E-03 0,08609672 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,944E-03 0,08571063 ! response to arsenic GO:0046685 10 5 0,000 7,944E-03 0,085328 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,944E-03 0,08494876 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,944E-03 0,08457288 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 7,944E-03 0,08420031 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 7,944E-03 0,08383101 ! response to cadmium ion GO:0046686 7 5 0,000 7,944E-03 0,08346494 ! bile acid biosynthetic process GO:0006699 6 5 0,000 7,944E-03 0,08310205 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 7,944E-03 0,0827423 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,944E-03 0,08238565 ! decidualization GO:0046697 11 5 0,000 7,944E-03 0,08203206 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 7,944E-03 0,0816815 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 7,944E-03 0,08133392 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,944E-03 0,08098928 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,944E-03 0,08064756 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 7,944E-03 0,0803087 ! base conversion or substitution editing GO:0016553 5 5 0,000 7,944E-03 0,07997268 ! neural tube patterning GO:0021532 7 5 0,000 7,944E-03 0,07963946 ! embryonic cleavage GO:0040016 6 5 0,000 7,944E-03 0,07930901 ! peroxisome fission GO:0016559 5 5 0,000 7,944E-03 0,07898129 ! histone demethylation GO:0016577 10 5 0,000 7,944E-03 0,07865626 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 7,944E-03 0,0783339 ! mitotic recombination GO:0006312 9 5 0,000 7,944E-03 0,07801417 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,944E-03 0,07769704 ! metaphase plate congression GO:0051310 7 5 0,000 7,944E-03 0,07738247 ! regulation of sterol transport GO:0032371 7 5 0,000 7,944E-03 0,07707045 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,944E-03 0,07676093 ! enteric nervous system development GO:0048484 8 5 0,000 7,944E-03 0,07645388 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 7,944E-03 0,07614929 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 7,944E-03 0,07584711 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 7,944E-03 0,07554732 ! muscle cell proliferation GO:0033002 11 5 0,000 7,944E-03 0,07524989 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,944E-03 0,07495479 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 7,944E-03 0,074662 ! plasminogen activation GO:0031639 5 5 0,000 7,944E-03 0,07437148 ! B cell homeostasis GO:0001782 13 5 0,000 7,944E-03 0,07408322 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,944E-03 0,07379719 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,944E-03 0,07351335 ! metaphase GO:0051323 8 5 0,000 7,944E-03 0,07323169 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 7,944E-03 0,07295218 ! cellular response to nutrient GO:0031670 8 5 0,000 7,944E-03 0,07267479 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,944E-03 0,07239951 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,944E-03 0,07212631 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,944E-03 0,07185515 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 7,944E-03 0,07158603 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 7,944E-03 0,07131892 ! response to redox state GO:0051775 5 5 0,000 7,944E-03 0,0710538 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 7,944E-03 0,07079063 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 7,944E-03 0,07052941 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,944E-03 0,07027011 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,944E-03 0,07001271 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,944E-03 0,06975719 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 7,944E-03 0,06950353 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,944E-03 0,06925171 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 7,944E-03 0,0690017 ! striatum development GO:0021756 9 5 0,000 7,944E-03 0,06875349 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 7,944E-03 0,06850706 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,944E-03 0,0682624 ! glial cell migration GO:0008347 11 5 0,000 7,944E-03 0,06801947 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,944E-03 0,06777827 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 7,944E-03 0,06753877 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,944E-03 0,06730095 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,944E-03 0,06706481 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,944E-03 0,06683032 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,944E-03 0,06659746 ! neuroprotection GO:0043526 6 5 0,000 7,944E-03 0,06636622 ! neural plate development GO:0001840 8 5 0,000 7,944E-03 0,06613658 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,944E-03 0,06590852 ! regulation of sensory perception GO:0051931 7 5 0,000 7,944E-03 0,06568203 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,944E-03 0,06545709 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 7,944E-03 0,06523369 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 7,944E-03 0,06501181 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,944E-03 0,06479143 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,944E-03 0,06457254 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,944E-03 0,06435512 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,944E-03 0,06413916 ! spindle assembly GO:0051225 6 5 0,000 7,944E-03 0,06392465 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 7,944E-03 0,06371157 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,944E-03 0,0634999 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,944E-03 0,06328964 ! drug metabolic process GO:0017144 6 5 0,000 7,944E-03 0,06308076 ! stem cell division GO:0017145 11 5 0,000 7,944E-03 0,06287326 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,944E-03 0,06266712 ! organ regeneration GO:0031100 7 5 0,000 7,944E-03 0,06246232 ! carnitine metabolic process GO:0009437 7 5 0,000 7,944E-03 0,06225886 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 7,944E-03 0,06205672 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,944E-03 0,06185589 ! regulation of ligase activity GO:0051340 142 84 1,000 7,979E-03 0,06192424 ! response to inorganic substance GO:0010035 153 86 1,000 8,349E-03 0,06458693 ! cellular respiration GO:0045333 135 88 1,000 8,726E-03 0,06729114 ! positive regulation of protein modification process GO:0031401 136 88 1,000 8,726E-03 0,06707615 ! regulation of cell adhesion GO:0030155 212 89 1,000 8,918E-03 0,06833057 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,525E-03 0,07275646 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,525E-03 0,07252622 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,525E-03 0,07229743 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,525E-03 0,07207008 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,525E-03 0,07184415 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,525E-03 0,07161964 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,525E-03 0,07139653 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,525E-03 0,0711748 ! sleep GO:0030431 13 6 0,000 9,525E-03 0,07095444 ! response to oxygen radical GO:0000305 11 6 0,000 9,525E-03 0,07073545 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,525E-03 0,0705178 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,525E-03 0,07030149 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,525E-03 0,0700865 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,525E-03 0,06987282 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,525E-03 0,06966044 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,525E-03 0,06944935 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,525E-03 0,06923953 ! forebrain regionalization GO:0021871 8 6 0,000 9,525E-03 0,06903098 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,525E-03 0,06882368 ! male meiosis GO:0007140 7 6 0,000 9,525E-03 0,06861762 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,525E-03 0,06841279 ! response to zinc ion GO:0010043 9 6 0,000 9,525E-03 0,06820918 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,525E-03 0,06800678 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,525E-03 0,06780558 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,525E-03 0,06760556 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,525E-03 0,06740672 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,525E-03 0,06720905 ! malate metabolic process GO:0006108 11 6 0,000 9,525E-03 0,06701253 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,525E-03 0,06681716 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,525E-03 0,06662292 ! protein refolding GO:0042026 15 6 0,000 9,525E-03 0,06642981 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,525E-03 0,06623782 ! opsonization GO:0008228 8 6 0,000 9,525E-03 0,06604693 ! mating behavior GO:0007617 7 6 0,000 9,525E-03 0,06585714 ! neuron remodeling GO:0016322 15 6 0,000 9,525E-03 0,06566844 ! erythrocyte maturation GO:0043249 7 6 0,000 9,525E-03 0,06548081 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,525E-03 0,06529426 ! equilibrioception GO:0050957 14 6 0,000 9,525E-03 0,06510876 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,525E-03 0,06492432 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,525E-03 0,06474092 ! photoreceptor cell development GO:0042461 10 6 0,000 9,525E-03 0,06455855 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,525E-03 0,0643772 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,525E-03 0,06419688 ! response to interferon-gamma GO:0034341 15 6 0,000 9,525E-03 0,06401756 ! toxin metabolic process GO:0009404 11 6 0,000 9,525E-03 0,06383923 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,525E-03 0,0636619 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,525E-03 0,06348555 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,525E-03 0,06331018 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,525E-03 0,06313577 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,525E-03 0,06296232 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,525E-03 0,06278982 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,525E-03 0,06261826 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,525E-03 0,06244764 ! thymic T cell selection GO:0045061 12 6 0,000 9,525E-03 0,06227795 ! protein lipoylation GO:0009249 10 6 0,000 9,525E-03 0,06210917 ! cysteine metabolic process GO:0006534 10 6 0,000 9,525E-03 0,06194131 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,525E-03 0,06177435 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,525E-03 0,06160829 ! glutamate catabolic process GO:0006538 10 6 0,000 9,525E-03 0,06144312 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,525E-03 0,06127884 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,525E-03 0,06111543 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 9,525E-03 0,06095289 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,525E-03 0,06079121 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,525E-03 0,06063038 ! hyperosmotic response GO:0006972 9 6 0,000 9,525E-03 0,06047041 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,525E-03 0,06031128 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,525E-03 0,06015298 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,525E-03 0,05999551 ! urea metabolic process GO:0019627 7 6 0,000 9,525E-03 0,05983886 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,525E-03 0,05968303 ! neutrophil activation GO:0042119 8 6 0,000 9,525E-03 0,05952801 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,525E-03 0,0593738 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,525E-03 0,05922037 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,525E-03 0,05906774 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,525E-03 0,0589159 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,525E-03 0,05876483 ! neuron apoptosis GO:0051402 9 6 0,000 9,525E-03 0,05861454 ! nucleoside salvage GO:0043174 9 6 0,000 9,525E-03 0,05846501 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,525E-03 0,05831625 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,525E-03 0,05816824 ! T cell mediated immunity GO:0002456 16 6 0,000 9,525E-03 0,05802097 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,525E-03 0,05787446 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,525E-03 0,05772868 ! carnitine transport GO:0015879 10 6 0,000 9,525E-03 0,05758363 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,525E-03 0,05743931 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,525E-03 0,05729571 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,525E-03 0,05715283 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,525E-03 0,05701066 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,525E-03 0,05686919 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,525E-03 0,05672843 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,525E-03 0,05658836 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,525E-03 0,05644898 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,525E-03 0,05631028 ! establishment of spindle localization GO:0051293 12 6 0,000 9,525E-03 0,05617227 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,525E-03 0,05603493 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,525E-03 0,05589826 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,525E-03 0,05576225 ! neural nucleus development GO:0048857 14 6 0,000 9,525E-03 0,05562691 ! response to UV-C GO:0010225 11 6 0,000 9,525E-03 0,05549222 ! astrocyte development GO:0014002 15 6 0,000 9,525E-03 0,05535818 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,525E-03 0,05522478 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,525E-03 0,05509203 ! interaction with symbiont GO:0051702 13 6 0,000 9,525E-03 0,05495992 ! regulation of dendrite development GO:0050773 16 6 0,000 9,525E-03 0,05482843 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,525E-03 0,05469758 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,525E-03 0,05456734 ! response to copper ion GO:0046688 10 6 0,000 9,525E-03 0,05443773 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,525E-03 0,05430873 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,525E-03 0,05418034 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,525E-03 0,05405256 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,525E-03 0,05392538 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,525E-03 0,05379879 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,525E-03 0,0536728 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,525E-03 0,05354739 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,525E-03 0,05342258 ! hair follicle maturation GO:0048820 7 6 0,000 9,525E-03 0,05329834 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,525E-03 0,05317467 ! Schwann cell development GO:0014044 15 6 0,000 9,525E-03 0,05305159 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,525E-03 0,05292906 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,525E-03 0,05280711 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,525E-03 0,05268571 ! subpallium development GO:0021544 10 6 0,000 9,525E-03 0,05256487 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,525E-03 0,05244459 ! histone ubiquitination GO:0016574 8 6 0,000 9,525E-03 0,05232485 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,525E-03 0,05220566 ! maintenance of organ identity GO:0048496 9 6 0,000 9,525E-03 0,05208701 ! G2 phase GO:0051319 16 6 0,000 9,525E-03 0,0519689 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,525E-03 0,05185132 ! establishment of planar polarity GO:0001736 7 6 0,000 9,525E-03 0,05173428 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,525E-03 0,05161776 ! membrane to membrane docking GO:0022614 14 6 0,000 9,525E-03 0,05150176 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,525E-03 0,05138629 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,525E-03 0,05127133 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,525E-03 0,05115689 ! receptor internalization GO:0031623 10 6 0,000 9,525E-03 0,05104295 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,525E-03 0,05092952 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,525E-03 0,0508166 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,525E-03 0,05070417 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,525E-03 0,05059224 ! protein deubiquitination GO:0016579 14 6 0,000 9,525E-03 0,0504808 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,525E-03 0,05036986 ! protein destabilization GO:0031648 9 6 0,000 9,525E-03 0,0502594 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,525E-03 0,05014942 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,525E-03 0,05003992 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,525E-03 0,0499309 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,525E-03 0,04982236 ! progesterone metabolic process GO:0042448 10 6 0,000 9,525E-03 0,04971428 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,525E-03 0,04960668 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,525E-03 0,04949954 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,525E-03 0,04939286 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,525E-03 0,04928663 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,525E-03 0,04918087 ! determination of adult lifespan GO:0008340 15 6 0,000 9,525E-03 0,04907556 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,525E-03 0,04897069 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,525E-03 0,04886628 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,525E-03 0,04876231 ! catecholamine transport GO:0051937 9 6 0,000 9,525E-03 0,04865878 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,525E-03 0,04855569 ! sensory cilium assembly GO:0035058 10 6 0,000 9,525E-03 0,04845303 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,525E-03 0,04835081 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,525E-03 0,04824902 ! maternal placenta development GO:0001893 12 6 0,000 9,525E-03 0,04814766 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,525E-03 0,04804672 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,525E-03 0,0479462 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,525E-03 0,04784611 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,525E-03 0,04774643 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,525E-03 0,04764716 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 9,525E-03 0,04754831 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,525E-03 0,04744987 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 9,703E-03 0,04823296 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01010643 0,05013623 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,01010643 0,05003307 ! response to virus GO:0009615 160 98 1,000 0,0107258 0,0529903 ! interphase GO:0051325 213 98 1,000 0,0107258 0,05288172 ! tRNA transcription GO:0009304 14 7 0,000 0,01110439 0,05463632 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01110439 0,05452482 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01110439 0,05441377 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01110439 0,05430317 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01110439 0,05419302 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01110439 0,05408332 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01110439 0,05397406 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01110439 0,05386524 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01110439 0,05375686 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01110439 0,05364892 ! prostate gland development GO:0030850 13 7 0,000 0,01110439 0,0535414 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01110439 0,05343432 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01110439 0,05332766 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01110439 0,05322143 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01110439 0,05311563 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01110439 0,05301024 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01110439 0,05290527 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01110439 0,05280071 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01110439 0,05269657 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01110439 0,05259283 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01110439 0,05248951 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01110439 0,05238659 ! glycolipid transport GO:0046836 10 7 0,000 0,01110439 0,05228407 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01110439 0,05218195 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01110439 0,05208023 ! neuron adhesion GO:0007158 12 7 0,000 0,01110439 0,05197891 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01110439 0,05187798 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01110439 0,05177744 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01110439 0,05167729 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01110439 0,05157753 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01110439 0,05147815 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01110439 0,05137915 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01110439 0,05128054 ! mRNA stabilization GO:0048255 18 7 0,000 0,01110439 0,0511823 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01110439 0,05108444 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01110439 0,05098695 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01110439 0,05088983 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01110439 0,05079308 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01110439 0,0506967 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01110439 0,05060068 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01110439 0,05050503 ! lipoprotein transport GO:0042953 14 7 0,000 0,01110439 0,05040974 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01110439 0,0503148 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01110439 0,05022023 ! rhythmic behavior GO:0007622 15 7 0,000 0,01110439 0,050126 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01110439 0,05003213 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01110439 0,04993862 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01110439 0,04984545 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01110439 0,04975263 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01110439 0,04966015 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01110439 0,04956801 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01110439 0,04947622 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01110439 0,04938477 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01110439 0,04929365 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01110439 0,04920287 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01110439 0,04911243 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01110439 0,04902231 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01110439 0,04893253 ! spinal cord patterning GO:0021511 13 7 0,000 0,01110439 0,04884307 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01110439 0,04875394 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01110439 0,04866514 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01110439 0,04857665 ! adrenal gland development GO:0030325 17 7 0,000 0,01110439 0,04848849 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01110439 0,04840065 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01110439 0,04831313 ! ovulation GO:0030728 9 7 0,000 0,01110439 0,04822592 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01110439 0,04813903 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01110439 0,04805245 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01110439 0,04796618 ! microtubule nucleation GO:0007020 20 7 0,000 0,01110439 0,04788021 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01110439 0,04779456 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01110439 0,04770921 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01110439 0,04762417 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01110439 0,04753943 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01110439 0,04745499 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01110439 0,04737085 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01110439 0,04728701 ! galactose metabolic process GO:0006012 13 7 0,000 0,01110439 0,04720346 ! vesicle fusion GO:0006906 17 7 0,000 0,01110439 0,04712021 ! response to dietary excess GO:0002021 8 7 0,000 0,01110439 0,04703725 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01110439 0,04695459 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01110439 0,04687221 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01110439 0,04679012 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01110439 0,04670832 ! organ growth GO:0035265 15 7 0,000 0,01110439 0,04662681 ! purine salvage GO:0043101 10 7 0,000 0,01110439 0,04654557 ! nucleoside transport GO:0015858 8 7 0,000 0,01110439 0,04646463 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01110439 0,04638396 ! parturition GO:0007567 14 7 0,000 0,01110439 0,04630357 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01110439 0,04622346 ! rRNA modification GO:0000154 14 7 0,000 0,01110439 0,04614363 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01110439 0,04606407 ! spindle checkpoint GO:0031577 15 7 0,000 0,01110439 0,04598478 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01110439 0,04590577 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01110439 0,04582703 ! macrophage differentiation GO:0030225 11 7 0,000 0,01110439 0,04574856 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01110439 0,04567036 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01110439 0,04559242 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01110439 0,04551475 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01110439 0,04543735 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01110439 0,0453602 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01110439 0,04528332 ! fibrinolysis GO:0042730 10 7 0,000 0,01110439 0,0452067 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01110439 0,04513034 ! eating behavior GO:0042755 7 7 0,000 0,01110439 0,04505423 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01110439 0,04497838 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01110439 0,04490279 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01110439 0,04482745 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01110439 0,04475236 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01110439 0,04467752 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01110439 0,04460294 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01110439 0,0445286 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01110439 0,04445451 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01110439 0,04438066 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01110439 0,04430706 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01110439 0,04423371 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01110439 0,04416059 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01110439 0,04408772 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01110439 0,04401509 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01110439 0,0439427 ! regulation of meiosis GO:0040020 12 7 0,000 0,01110439 0,04387054 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01110439 0,04379862 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01110439 0,04372694 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01110439 0,04365549 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01110439 0,04358427 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01110439 0,04351329 ! transcription termination GO:0006353 13 7 0,000 0,01110439 0,04344254 ! response to tumor cell GO:0002347 13 7 0,000 0,01110439 0,04337201 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01110439 0,04330172 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01110439 0,04323165 ! anaphase GO:0051322 17 7 0,000 0,01110439 0,04316181 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01110439 0,04309219 ! axonal fasciculation GO:0007413 18 7 0,000 0,01110439 0,0430228 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01110439 0,04295363 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01110439 0,04288469 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01110439 0,04281596 ! diuresis GO:0030146 12 7 0,000 0,01110439 0,04274746 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01110439 0,04267917 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01110439 0,0426111 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01110439 0,04254325 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01110439 0,04247561 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01110439 0,04240819 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01110439 0,04234098 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01110439 0,04227399 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01110439 0,0422072 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01110439 0,04214063 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01110439 0,04207427 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01110439 0,04200811 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01110439 0,04194217 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01110439 0,04187643 ! lymph node development GO:0048535 10 7 0,000 0,01110439 0,04181089 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01110439 0,04174556 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01110439 0,04168044 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01110439 0,04161551 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01110439 0,04155079 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01110439 0,04148627 ! adult feeding behavior GO:0008343 9 7 0,000 0,01110439 0,04142195 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01110439 0,04135783 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01110439 0,04129391 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01110439 0,04123018 ! muscle adaptation GO:0043500 14 7 0,000 0,01110439 0,04116666 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01110439 0,04110332 ! retina homeostasis GO:0001895 12 7 0,000 0,01110439 0,04104018 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01110439 0,04097724 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01110439 0,04091449 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01110439 0,04085193 ! protein prenylation GO:0018342 18 7 0,000 0,01110439 0,04078956 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01110439 0,04072738 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01110439 0,04066539 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01110439 0,04060359 ! cell cycle arrest GO:0007050 213 100 1,000 0,01114785 0,04070065 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01268084 0,04622743 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01268084 0,0461575 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01268084 0,04608777 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01268084 0,04601826 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01268084 0,04594895 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01268084 0,04587986 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01268084 0,04581097 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01268084 0,04574229 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01268084 0,04567381 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01268084 0,04560554 ! meiotic prophase I GO:0007128 13 8 0,000 0,01268084 0,04553747 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01268084 0,0454696 ! oligopeptide transport GO:0006857 15 8 0,000 0,01268084 0,04540194 ! UTP metabolic process GO:0046051 8 8 0,000 0,01268084 0,04533448 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01268084 0,04526722 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01268084 0,04520016 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01268084 0,04513329 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01268084 0,04506662 ! succinate metabolic process GO:0006105 14 8 0,000 0,01268084 0,04500015 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01268084 0,04493388 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01268084 0,0448678 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01268084 0,04480192 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01268084 0,04473622 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01268084 0,04467072 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01268084 0,04460542 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01268084 0,0445403 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01268084 0,04447537 ! reflex GO:0060004 16 8 0,000 0,01268084 0,04441063 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01268084 0,04434608 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01268084 0,04428172 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01268084 0,04421754 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01268084 0,04415355 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01268084 0,04408975 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01268084 0,04402613 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01268084 0,04396269 ! pigment granule organization GO:0048753 16 8 0,000 0,01268084 0,04389943 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01268084 0,04383636 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01268084 0,04377346 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01268084 0,04371075 ! histidine metabolic process GO:0006547 16 8 0,000 0,01268084 0,04364822 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01268084 0,04358586 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01268084 0,04352369 ! glycine catabolic process GO:0006546 13 8 0,000 0,01268084 0,04346169 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01268084 0,04339986 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01268084 0,04333822 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01268084 0,04327674 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01268084 0,04321545 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01268084 0,04315432 ! melanin metabolic process GO:0006582 15 8 0,000 0,01268084 0,04309337 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01268084 0,04303259 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01268084 0,04297198 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01268084 0,04291154 ! macrophage activation GO:0042116 12 8 0,000 0,01268084 0,04285127 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01268084 0,04279117 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01268084 0,04273124 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01268084 0,04267148 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01268084 0,04261188 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01268084 0,04255245 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01268084 0,04249318 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01268084 0,04243408 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01268084 0,04237515 ! osteoblast development GO:0002076 16 8 0,000 0,01268084 0,04231637 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01268084 0,04225776 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01268084 0,04219932 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01268084 0,04214103 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01268084 0,0420829 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01268084 0,04202494 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01268084 0,04196713 ! response to UV-B GO:0010224 16 8 0,000 0,01268084 0,04190948 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01268084 0,041852 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01268084 0,04179466 ! intermediate filament organization GO:0045109 12 8 0,000 0,01268084 0,04173749 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01268084 0,04168047 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01268084 0,04162361 ! cellular extravasation GO:0045123 12 8 0,000 0,01268084 0,0415669 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01268084 0,04151035 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01268084 0,04145395 ! response to antibiotic GO:0046677 11 8 0,000 0,01268084 0,0413977 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01268084 0,04134161 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01268084 0,04128566 ! DNA topological change GO:0006265 12 8 0,000 0,01268084 0,04122987 ! response to tropane GO:0014073 15 8 0,000 0,01268084 0,04117423 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01268084 0,04111874 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01268084 0,0410634 ! melanosome transport GO:0032402 13 8 0,000 0,01268084 0,04100821 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01268084 0,04095316 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01268084 0,04089826 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01268084 0,04084351 ! mast cell activation GO:0045576 14 8 0,000 0,01268084 0,04078891 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01268084 0,04073445 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01268084 0,04068014 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01268084 0,04062597 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01268084 0,04057195 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01268084 0,04051807 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01268084 0,04046433 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01268084 0,04041073 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01268084 0,04035728 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01268084 0,04030397 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01268084 0,0402508 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01268084 0,04019777 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01268084 0,04014487 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01268084 0,04009212 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01268084 0,04003951 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01268084 0,03998703 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01268084 0,03993469 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01268084 0,03988249 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01268084 0,03983042 ! hormone catabolic process GO:0042447 17 8 0,000 0,01268084 0,03977849 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01268084 0,0397267 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01268084 0,03967504 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01268084 0,03962351 ! ATP catabolic process GO:0006200 11 8 0,000 0,01268084 0,03957212 ! blastocyst growth GO:0001832 19 8 0,000 0,01268084 0,03952086 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01268084 0,03946973 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01268084 0,03941874 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01268084 0,03936788 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01268084 0,03931715 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01268084 0,03926654 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01268084 0,03921607 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01268084 0,03916573 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01268084 0,03911552 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01268084 0,03906544 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01268084 0,03901548 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01268084 0,03896565 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01268084 0,03891595 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01268084 0,03886638 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01268084 0,03881693 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01268084 0,0387676 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01268084 0,03871841 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01268084 0,03866933 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01425483 0,04341409 ! axon extension GO:0048675 15 9 0,000 0,01425483 0,0433592 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01425483 0,04330446 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01425483 0,04324985 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01425483 0,04319538 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01425483 0,04314104 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01425483 0,04308685 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01425483 0,04303278 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01425483 0,04297886 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01425483 0,04292507 ! phosphate transport GO:0006817 19 9 0,000 0,01425483 0,04287141 ! reproductive behavior GO:0019098 19 9 0,000 0,01425483 0,04281789 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01425483 0,0427645 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01425483 0,04271124 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01425483 0,04265812 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01425483 0,04260513 ! GTP metabolic process GO:0046039 9 9 0,000 0,01425483 0,04255227 ! RNA methylation GO:0001510 15 9 0,000 0,01425483 0,04249954 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01425483 0,04244694 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01425483 0,04239447 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01425483 0,04234213 ! artery development GO:0060840 24 9 0,000 0,01425483 0,04228992 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01425483 0,04223784 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01425483 0,04218589 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01425483 0,04213407 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01425483 0,04208237 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01425483 0,0420308 ! chemosensory behavior GO:0007635 20 9 0,000 0,01425483 0,04197935 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01425483 0,04192803 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01425483 0,04187684 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01425483 0,04182577 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01425483 0,04177482 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01425483 0,041724 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01425483 0,0416733 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01425483 0,04162273 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01425483 0,04157228 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01425483 0,04152195 ! protein targeting to ER GO:0045047 22 9 0,000 0,01425483 0,04147174 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01425483 0,04142165 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01425483 0,04137169 ! T cell selection GO:0045058 23 9 0,000 0,01425483 0,04132184 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01425483 0,04127212 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01425483 0,04122251 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01425483 0,04117302 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01425483 0,04112366 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01425483 0,04107441 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01425483 0,04102527 ! mannose metabolic process GO:0006013 13 9 0,000 0,01425483 0,04097626 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01425483 0,04092736 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01425483 0,04087858 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01425483 0,04082992 ! receptor clustering GO:0043113 18 9 0,000 0,01425483 0,04078137 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01425483 0,04073293 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01425483 0,04068461 ! ruffle organization GO:0031529 15 9 0,000 0,01425483 0,04063641 ! retinol metabolic process GO:0042572 18 9 0,000 0,01425483 0,04058832 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01425483 0,04054034 ! behavioral fear response GO:0001662 22 9 0,000 0,01425483 0,04049248 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01425483 0,04044473 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01425483 0,04039709 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01425483 0,04034956 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01425483 0,04030215 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01425483 0,04025485 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01425483 0,04020765 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01425483 0,04016057 ! segment specification GO:0007379 13 9 0,000 0,01425483 0,0401136 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01425483 0,04006674 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01425483 0,04001999 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01425483 0,03997334 ! response to amine stimulus GO:0014075 13 9 0,000 0,01425483 0,03992681 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01425483 0,03988038 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01425483 0,03983406 ! erythrocyte development GO:0048821 15 9 0,000 0,01425483 0,03978785 ! gas homeostasis GO:0033483 16 9 0,000 0,01425483 0,03974175 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01425483 0,03969575 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01425483 0,03964986 ! renal water homeostasis GO:0003091 14 9 0,000 0,01425483 0,03960408 ! postreplication repair GO:0006301 22 9 0,000 0,01425483 0,0395584 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01425483 0,03951282 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01425483 0,03946735 ! icosanoid secretion GO:0032309 15 9 0,000 0,01425483 0,03942199 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01425483 0,03937673 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01425483 0,03933157 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01425483 0,03928652 ! regulation of cell division GO:0051302 15 9 0,000 0,01425483 0,03924157 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01425483 0,03919672 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01425483 0,03915197 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01425483 0,03910733 ! sterol catabolic process GO:0016127 11 9 0,000 0,01425483 0,03906279 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01425483 0,03901835 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01425483 0,03897401 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01425483 0,03892977 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01425483 0,03888563 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01425483 0,0388416 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01425483 0,03879766 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01425483 0,03875382 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01425483 0,03871008 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01425483 0,03866644 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01425483 0,03862289 ! purine base metabolic process GO:0006144 21 9 0,000 0,01425483 0,03857945 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01425483 0,0385361 ! pigment granule transport GO:0051904 17 9 0,000 0,01425483 0,03849285 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01425483 0,0384497 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01425483 0,03840664 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01425483 0,03836368 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01425483 0,03832081 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01425483 0,03827805 ! mitochondrion localization GO:0051646 15 9 0,000 0,01425483 0,03823537 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01582637 0,04240339 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01582637 0,04235622 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01582637 0,04230916 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01582637 0,0422622 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01582637 0,04221535 ! synapsis GO:0007129 13 10 0,000 0,01582637 0,0421686 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01582637 0,04212195 ! N-glycan processing GO:0006491 20 10 0,000 0,01582637 0,04207541 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01582637 0,04202896 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01582637 0,04198263 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01582637 0,04193639 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01582637 0,04189025 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01582637 0,04184422 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01582637 0,04179829 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01582637 0,04175246 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01582637 0,04170673 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01582637 0,0416611 ! androgen metabolic process GO:0008209 17 10 0,000 0,01582637 0,04161556 ! phospholipid efflux GO:0033700 16 10 0,000 0,01582637 0,04157013 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01582637 0,0415248 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01582637 0,04147957 ! lung alveolus development GO:0048286 26 10 0,000 0,01582637 0,04143443 ! pathogenesis GO:0009405 13 10 0,000 0,01582637 0,04138939 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01582637 0,04134445 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01582637 0,04129961 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01582637 0,04125487 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01582637 0,04121022 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01582637 0,04116567 ! endoderm development GO:0007492 16 10 0,000 0,01582637 0,04112121 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01582637 0,04107685 ! arginine catabolic process GO:0006527 13 10 0,000 0,01582637 0,04103259 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01582637 0,04098842 ! proline metabolic process GO:0006560 13 10 0,000 0,01582637 0,04094435 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01582637 0,04090037 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01582637 0,04085648 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01582637 0,04081269 ! V(D)J recombination GO:0033151 28 10 0,000 0,01582637 0,040769 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01582637 0,04072539 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01582637 0,04068188 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 0,01582637 0,04063847 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01582637 0,04059514 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01582637 0,04055191 ! multicellular organism growth GO:0035264 18 10 0,000 0,01582637 0,04050877 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01582637 0,04046572 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01582637 0,04042276 ! epithelial cell development GO:0002064 20 10 0,000 0,01582637 0,0403799 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01582637 0,04033712 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01582637 0,04029444 ! macroautophagy GO:0016236 17 10 0,000 0,01582637 0,04025184 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01582637 0,04020934 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01582637 0,04016692 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01582637 0,0401246 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01582637 0,04008236 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01582637 0,04004021 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01582637 0,03999815 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01582637 0,03995618 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01582637 0,0399143 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01582637 0,0398725 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01582637 0,0398308 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01582637 0,03978918 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01582637 0,03974764 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01582637 0,0397062 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01582637 0,03966484 ! response to dsRNA GO:0043331 20 10 0,000 0,01582637 0,03962356 ! DNA ligation GO:0006266 19 10 0,000 0,01582637 0,03958237 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01582637 0,03954127 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01582637 0,03950025 ! melanosome localization GO:0032400 16 10 0,000 0,01582637 0,03945932 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01582637 0,03941847 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01582637 0,03937771 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01582637 0,03933703 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01582637 0,03929643 ! mRNA cleavage GO:0006379 17 10 0,000 0,01582637 0,03925592 ! protein sumoylation GO:0016925 15 10 0,000 0,01582637 0,03921549 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01582637 0,03917515 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01582637 0,03913488 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01582637 0,0390947 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01582637 0,03905461 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01582637 0,03901459 ! salivary gland development GO:0007431 27 10 0,000 0,01582637 0,03897466 ! prophase GO:0051324 15 10 0,000 0,01582637 0,03893481 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01582637 0,03889504 ! apical protein localization GO:0045176 15 10 0,000 0,01582637 0,03885535 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01582637 0,03881574 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01582637 0,03877621 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01582637 0,03873677 ! midbrain development GO:0030901 13 10 0,000 0,01582637 0,0386974 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01582637 0,03865811 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01582637 0,03861891 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01582637 0,03857978 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01582637 0,03854073 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01582637 0,03850176 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01582637 0,03846287 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01582637 0,03842406 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01582637 0,03838532 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01582637 0,03834667 ! oocyte development GO:0048599 17 10 0,000 0,01582637 0,03830809 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01582637 0,03826959 ! blastocyst formation GO:0001825 17 10 0,000 0,01582637 0,03823117 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01582637 0,03819282 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01582637 0,03815455 ! activation of innate immune response GO:0002218 12 10 0,000 0,01582637 0,03811636 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01582637 0,03807824 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01582637 0,0380402 ! response to nicotine GO:0035094 20 10 0,000 0,01582637 0,03800224 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01582637 0,03796435 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01582637 0,03792654 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01582637 0,0378888 ! localization within membrane GO:0051668 20 10 0,000 0,01582637 0,03785113 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01739545 0,04156251 ! respiratory burst GO:0045730 17 11 0,000 0,01739545 0,04152128 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01739545 0,04148013 ! neuron fate specification GO:0048665 17 11 0,000 0,01739545 0,04143906 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01739545 0,04139807 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01739545 0,04135717 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01739545 0,04131634 ! thyroid gland development GO:0030878 26 11 0,000 0,01739545 0,04127559 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01739545 0,04123493 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01739545 0,04119434 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01739545 0,04115384 ! response to pain GO:0048265 24 11 0,000 0,01739545 0,04111341 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01739545 0,04107306 ! T cell proliferation GO:0042098 26 11 0,000 0,01739545 0,0410328 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01739545 0,04099261 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01739545 0,0409525 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01739545 0,04091246 ! bone resorption GO:0045453 16 11 0,000 0,01739545 0,04087251 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01739545 0,04083264 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01739545 0,04079284 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01739545 0,04075312 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01739545 0,04071347 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01739545 0,04067391 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01739545 0,04063442 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01739545 0,04059501 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01739545 0,04055567 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01739545 0,04051641 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01739545 0,04047723 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01739545 0,04043812 ! lipid digestion GO:0044241 18 11 0,000 0,01739545 0,04039908 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01739545 0,04036013 ! UV protection GO:0009650 19 11 0,000 0,01739545 0,04032124 ! adult heart development GO:0007512 14 11 0,000 0,01739545 0,04028244 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01739545 0,0402437 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01739545 0,04020504 ! temperature homeostasis GO:0001659 17 11 0,000 0,01739545 0,04016646 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01739545 0,04012795 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01739545 0,04008951 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01739545 0,04005115 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01739545 0,04001286 ! regulation of organ growth GO:0046620 13 11 0,000 0,01739545 0,03997464 ! pigment granule localization GO:0051875 20 11 0,000 0,01739545 0,0399365 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01739545 0,03989843 ! vasoconstriction GO:0042310 18 11 0,000 0,01739545 0,03986043 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01739545 0,0398225 ! embryonic axis specification GO:0000578 18 11 0,000 0,01739545 0,03978465 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01739545 0,03974687 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01739545 0,03970916 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01739545 0,03967152 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01739545 0,03963395 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01739545 0,03959645 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01739545 0,03955903 ! zymogen activation GO:0031638 15 11 0,000 0,01739545 0,03952167 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01739545 0,03948439 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01739545 0,03944717 ! nucleosome positioning GO:0016584 15 11 0,000 0,01739545 0,03941003 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01739545 0,03937296 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01739545 0,03933595 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01739545 0,03929902 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01739545 0,03926215 ! acid secretion GO:0046717 18 11 0,000 0,01739545 0,03922535 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01739545 0,03918863 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01739545 0,03915197 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01739545 0,03911538 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01739545 0,03907885 ! oocyte differentiation GO:0009994 18 11 0,000 0,01739545 0,0390424 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01739545 0,03900601 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01739545 0,03896969 ! cholesterol efflux GO:0033344 19 11 0,000 0,01739545 0,03893344 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01739545 0,03889726 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01739545 0,03886114 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01739545 0,03882509 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01739545 0,03878911 ! embryonic gut development GO:0048566 15 11 0,000 0,01739545 0,0387532 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01739545 0,03871735 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01739545 0,03868156 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01739545 0,03864585 ! defense response to fungus GO:0050832 13 11 0,000 0,01739545 0,0386102 ! developmental induction GO:0031128 19 11 0,000 0,01739545 0,03857461 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01739545 0,03853909 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01739545 0,03850364 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01739545 0,03846825 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01739545 0,03843292 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01739545 0,03839766 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01739545 0,03836247 ! nucleus localization GO:0051647 19 11 0,000 0,01739545 0,03832734 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01739545 0,03829227 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01896208 0,04170271 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01896208 0,04166463 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01896208 0,04162661 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01896208 0,04158867 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01896208 0,04155079 ! virus-host interaction GO:0019048 29 12 0,000 0,01896208 0,04151298 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01896208 0,04147524 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01896208 0,04143757 ! cartilage condensation GO:0001502 20 12 0,000 0,01896208 0,04139997 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01896208 0,04136244 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01896208 0,04132497 ! protein complex disassembly GO:0043241 27 12 0,000 0,01896208 0,04128757 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01896208 0,04125024 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01896208 0,04121298 ! hippocampus development GO:0021766 26 12 0,000 0,01896208 0,04117578 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01896208 0,04113865 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01896208 0,04110159 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01896208 0,0410646 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01896208 0,04102767 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01896208 0,04099081 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01896208 0,04095401 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01896208 0,04091728 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01896208 0,04088062 ! drug transport GO:0015893 16 12 0,000 0,01896208 0,04084402 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01896208 0,04080748 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01896208 0,04077102 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01896208 0,04073461 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01896208 0,04069828 ! focal adhesion formation GO:0048041 35 12 0,000 0,01896208 0,040662 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01896208 0,0406258 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01896208 0,04058965 ! forebrain cell migration GO:0021885 21 12 0,000 0,01896208 0,04055357 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01896208 0,04051756 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01896208 0,0404816 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01896208 0,04044572 ! entry into host cell GO:0030260 32 12 0,000 0,01896208 0,04040989 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01896208 0,04037413 ! monoamine transport GO:0015844 18 12 0,000 0,01896208 0,04033843 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01896208 0,0403028 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01896208 0,04026723 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01896208 0,04023172 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01896208 0,04019627 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01896208 0,04016089 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01896208 0,04012557 ! protein homotetramerization GO:0051289 21 12 0,000 0,01896208 0,04009031 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01896208 0,04005511 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01896208 0,04001997 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01896208 0,0399849 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01896208 0,03994988 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01896208 0,03991493 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01896208 0,03988004 ! cranial nerve development GO:0021545 20 12 0,000 0,01896208 0,03984521 ! fucose catabolic process GO:0019317 22 12 0,000 0,01896208 0,03981044 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01896208 0,03977573 ! histone acetylation GO:0016573 26 12 0,000 0,01896208 0,03974109 ! histone methylation GO:0016571 26 12 0,000 0,01896208 0,0397065 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01896208 0,03967197 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01896208 0,0396375 ! gland morphogenesis GO:0022612 29 12 0,000 0,01896208 0,0396031 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01896208 0,03956875 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01896208 0,03953446 ! T cell homeostasis GO:0043029 25 12 0,000 0,01896208 0,03950023 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01896208 0,03946606 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01896208 0,03943195 ! spleen development GO:0048536 22 12 0,000 0,01896208 0,0393979 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01896208 0,03936391 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01896208 0,03932997 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01896208 0,0392961 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01896208 0,03926228 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01896208 0,03922852 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01896208 0,03919482 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01896208 0,03916117 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01896208 0,03912759 ! response to cold GO:0009409 17 12 0,000 0,01896208 0,03909406 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01896208 0,03906059 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01896208 0,03902718 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02052627 0,04221043 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02052627 0,04217438 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02052627 0,0421384 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02052627 0,04210247 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02052627 0,04206661 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02052627 0,04203081 ! lipid localization GO:0010876 28 13 0,000 0,02052627 0,04199507 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02052627 0,04195939 ! organelle fusion GO:0048284 32 13 0,000 0,02052627 0,04192377 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02052627 0,04188821 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02052627 0,04185271 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02052627 0,04181727 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02052627 0,04178189 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02052627 0,04174658 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02052627 0,04171132 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02052627 0,04167612 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02052627 0,04164098 ! methionine metabolic process GO:0006555 27 13 0,000 0,02052627 0,0416059 ! plasma membrane organization GO:0007009 24 13 0,000 0,02052627 0,04157087 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02052627 0,04153591 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02052627 0,04150101 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02052627 0,04146616 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02052627 0,04143138 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02052627 0,04139665 ! response to X-ray GO:0010165 25 13 0,000 0,02052627 0,04136198 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02052627 0,04132736 ! exocrine system development GO:0035272 32 13 0,000 0,02052627 0,04129281 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02052627 0,04125831 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02052627 0,04122387 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02052627 0,04118949 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02052627 0,04115517 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02052627 0,0411209 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02052627 0,04108669 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02052627 0,04105253 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02052627 0,04101844 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02052627 0,0409844 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02052627 0,04095041 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02052627 0,04091649 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02052627 0,04088262 ! ribosome assembly GO:0042255 17 13 0,000 0,02052627 0,0408488 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02052627 0,04081504 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02052627 0,04078134 ! chromatin silencing GO:0006342 26 13 0,000 0,02052627 0,04074769 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02052627 0,0407141 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02052627 0,04068056 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02052627 0,04064708 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02052627 0,04061365 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02052627 0,04058028 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02052627 0,04054696 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02052627 0,0405137 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02052627 0,04048049 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02052627 0,04044734 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02052627 0,04041424 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02052627 0,04038119 ! embryonic placenta development GO:0001892 23 13 0,000 0,02052627 0,0403482 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02052627 0,04031526 ! insulin secretion GO:0030073 23 13 0,000 0,02052627 0,04028238 ! actin filament polymerization GO:0030041 24 13 0,000 0,02052627 0,04024955 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02052627 0,04021677 ! acrosome reaction GO:0007340 18 13 0,000 0,02052627 0,04018405 ! rRNA transcription GO:0009303 25 14 0,000 0,02208801 0,04320631 ! lactation GO:0007595 26 14 0,000 0,02208801 0,04317121 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02208801 0,04313617 ! reproductive cellular process GO:0048610 20 14 0,000 0,02208801 0,04310118 ! tRNA modification GO:0006400 20 14 0,000 0,02208801 0,04306625 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02208801 0,04303138 ! regulation of S phase GO:0033261 23 14 0,000 0,02208801 0,04299657 ! water transport GO:0006833 21 14 0,000 0,02208801 0,04296181 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02208801 0,0429271 ! non-recombinational repair GO:0000726 25 14 0,000 0,02208801 0,04289246 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02208801 0,04285787 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02208801 0,04282333 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02208801 0,04278885 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02208801 0,04275443 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02208801 0,04272006 ! palate development GO:0060021 31 14 0,000 0,02208801 0,04268575 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02208801 0,04265149 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02208801 0,04261729 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02208801 0,04258314 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02208801 0,04254904 ! arginine metabolic process GO:0006525 17 14 0,000 0,02208801 0,042515 ! regulation of heart rate GO:0002027 24 14 0,000 0,02208801 0,04248102 ! organic alcohol transport GO:0015850 29 14 0,000 0,02208801 0,04244709 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02208801 0,04241321 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02208801 0,04237939 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02208801 0,04234562 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02208801 0,04231191 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02208801 0,04227825 ! L-amino acid transport GO:0015807 30 14 0,000 0,02208801 0,04224464 ! bone mineralization GO:0030282 17 14 0,000 0,02208801 0,04221108 ! stem cell development GO:0048864 43 14 0,000 0,02208801 0,04217758 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02208801 0,04214414 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02208801 0,04211074 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02208801 0,0420774 ! cerebellum development GO:0021549 21 14 0,000 0,02208801 0,04204411 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02208801 0,04201087 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02208801 0,04197769 ! response to gamma radiation GO:0010332 28 14 0,000 0,02208801 0,04194456 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02208801 0,04191148 ! cofactor transport GO:0051181 26 14 0,000 0,02208801 0,04187845 ! NADP metabolic process GO:0006739 24 14 0,000 0,02208801 0,04184548 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02208801 0,04181255 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02208801 0,04177968 ! intestinal absorption GO:0050892 25 14 0,000 0,02208801 0,04174686 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02208801 0,04171409 ! oxygen transport GO:0015671 21 14 0,000 0,02208801 0,04168138 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02208801 0,04164871 ! male genitalia development GO:0030539 24 14 0,000 0,02208801 0,0416161 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02208801 0,04158353 ! regulation of axon extension GO:0030516 37 14 0,000 0,02208801 0,04155102 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02208801 0,04151856 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02208801 0,04148615 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02364732 0,04438022 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02364732 0,04434563 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02364732 0,04431109 ! superoxide anion generation GO:0042554 20 15 0,000 0,02364732 0,04427661 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02364732 0,04424218 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02364732 0,0442078 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02364732 0,04417348 ! copper ion transport GO:0006825 20 15 0,000 0,02364732 0,04413921 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02364732 0,044105 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02364732 0,04407083 ! sulfate transport GO:0008272 23 15 0,000 0,02364732 0,04403672 ! response to cAMP GO:0051591 22 15 0,000 0,02364732 0,04400266 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02364732 0,04396866 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02364732 0,04393471 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02364732 0,04390081 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02364732 0,04386696 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02364732 0,04383316 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02364732 0,04379942 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02364732 0,04376573 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02364732 0,04373209 ! pituitary gland development GO:0021983 29 15 0,000 0,02364732 0,0436985 ! vesicle coating GO:0006901 33 15 0,000 0,02364732 0,04366496 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02364732 0,04363148 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02364732 0,04359804 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02364732 0,04356466 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02364732 0,04353133 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02364732 0,04349805 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02364732 0,04346482 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02364732 0,04343164 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02364732 0,04339851 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02364732 0,04336543 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02364732 0,0433324 ! histone deacetylation GO:0016575 20 15 0,000 0,02364732 0,04329943 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02364732 0,0432665 ! tissue regeneration GO:0042246 26 15 0,000 0,02364732 0,04323362 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02364732 0,04320079 ! water homeostasis GO:0030104 27 15 0,000 0,02364732 0,04316802 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02364732 0,04313529 ! muscle maintenance GO:0046716 26 15 0,000 0,02364732 0,04310261 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02364732 0,04306998 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02364732 0,0430374 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02364732 0,04300487 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02364732 0,04297239 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02364732 0,04293996 ! cell killing GO:0001906 29 15 0,000 0,02364732 0,04290758 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02364732 0,04287524 ! detection of bacterium GO:0016045 18 15 0,000 0,02364732 0,04284296 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02364732 0,04281072 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02364732 0,04277853 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02364732 0,04274639 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02364732 0,0427143 ! peptide hormone processing GO:0016486 23 15 0,000 0,02364732 0,04268225 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02520419 0,04545823 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02520419 0,04542418 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02520419 0,04539018 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02520419 0,04535623 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02520419 0,04532233 ! bone remodeling GO:0046849 27 16 0,000 0,02520419 0,04528848 ! filopodium assembly GO:0046847 32 16 0,000 0,02520419 0,04525468 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02520419 0,04522094 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02520419 0,04518724 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02520419 0,04515359 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02520419 0,04512 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02520419 0,04508645 ! startle response GO:0001964 28 16 0,000 0,02520419 0,04505295 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02520419 0,04501951 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02520419 0,04498611 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02520419 0,04495276 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02520419 0,04491946 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02520419 0,04488621 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02520419 0,04485301 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02520419 0,04481986 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02520419 0,04478676 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02520419 0,04475371 ! response to osmotic stress GO:0006970 25 16 0,000 0,02520419 0,04472071 ! lysosomal transport GO:0007041 26 16 0,000 0,02520419 0,04468775 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02520419 0,04465484 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,02520419 0,04462198 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02520419 0,04458917 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02520419 0,04455641 ! axon cargo transport GO:0008088 43 16 0,000 0,02520419 0,0445237 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02520419 0,04449103 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02520419 0,04445841 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02520419 0,04442584 ! DNA replication initiation GO:0006270 27 16 0,000 0,02520419 0,04439332 ! neuron recognition GO:0008038 35 16 0,000 0,02520419 0,04436085 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02520419 0,04432842 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02520419 0,04429604 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02520419 0,04426371 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02520419 0,04423142 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02520419 0,04419918 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02520419 0,04416699 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02520419 0,04413484 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02520419 0,04410275 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02520419 0,04407069 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02520419 0,04403869 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02520419 0,04400673 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02520419 0,04397482 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02520419 0,04394295 ! defense response to virus GO:0051607 37 16 0,000 0,02520419 0,04391113 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02675863 0,04658557 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02675863 0,04655189 ! metencephalon development GO:0022037 30 17 0,000 0,02675863 0,04651825 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02675863 0,04648466 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02675863 0,04645112 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02675863 0,04641763 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02675863 0,04638419 ! signal complex assembly GO:0007172 41 17 0,000 0,02675863 0,0463508 ! endothelial cell migration GO:0043542 28 17 0,000 0,02675863 0,04631745 ! inositol metabolic process GO:0006020 28 17 0,000 0,02675863 0,04628415 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02675863 0,0462509 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02675863 0,0462177 ! glial cell development GO:0021782 27 17 0,000 0,02675863 0,04618455 ! limbic system development GO:0021761 36 17 0,000 0,02675863 0,04615144 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02675863 0,04611838 ! adult walking behavior GO:0007628 33 17 0,000 0,02675863 0,04608537 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02675863 0,0460524 ! heart looping GO:0001947 30 17 0,000 0,02675863 0,04601948 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02675863 0,04598661 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02675863 0,04595379 ! myoblast differentiation GO:0045445 45 17 0,000 0,02675863 0,04592101 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02675863 0,04588828 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02675863 0,0458556 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02675863 0,04582296 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02675863 0,04579037 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02675863 0,04575782 ! glycine metabolic process GO:0006544 28 17 0,000 0,02675863 0,04572533 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02675863 0,04569287 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02675863 0,04566047 ! NAD metabolic process GO:0019674 29 17 0,000 0,02675863 0,04562811 ! membrane budding GO:0006900 37 17 0,000 0,02675863 0,04559579 ! DNA integration GO:0015074 29 17 0,000 0,02675863 0,04556352 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02675863 0,0455313 ! regulation of protein binding GO:0043393 33 17 0,000 0,02675863 0,04549912 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02675863 0,04546699 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02675863 0,0454349 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02675863 0,04540286 ! genitalia development GO:0048806 30 17 0,000 0,02675863 0,04537087 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02675863 0,04533891 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02675863 0,04530701 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02675863 0,04527515 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02675863 0,04524333 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02675863 0,04521156 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02675863 0,04517983 ! steroid catabolic process GO:0006706 31 17 0,000 0,02675863 0,04514815 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02675863 0,04511651 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02675863 0,04508492 ! gas transport GO:0015669 25 17 0,000 0,02675863 0,04505337 ! organic cation transport GO:0015695 31 17 0,000 0,02675863 0,04502186 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02675863 0,0449904 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02675863 0,04495898 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02675863 0,04492761 ! microspike assembly GO:0030035 36 17 0,000 0,02675863 0,04489628 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02675863 0,04486499 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02831064 0,04743412 ! neuron maturation GO:0042551 42 18 0,000 0,02831064 0,04740111 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02831064 0,04736815 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02831064 0,04733523 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02831064 0,04730236 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02831064 0,04726954 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02831064 0,04723676 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02831064 0,04720402 ! memory GO:0007613 31 18 0,000 0,02831064 0,04717133 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02831064 0,04713869 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02831064 0,04710609 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02831064 0,04707353 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02831064 0,04704102 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02831064 0,04700856 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02831064 0,04697614 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02831064 0,04694376 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02831064 0,04691143 ! response to retinoic acid GO:0032526 26 18 0,000 0,02831064 0,04687915 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02831064 0,04684691 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02831064 0,04681471 ! response to fungus GO:0009620 21 18 0,000 0,02831064 0,04678256 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02831064 0,04675045 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02831064 0,04671838 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02831064 0,04668636 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02831064 0,04665438 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02831064 0,04662245 ! vitamin transport GO:0051180 27 18 0,000 0,02831064 0,04659056 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02831064 0,04655872 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02831064 0,04652691 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02831064 0,04649515 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02831064 0,04646344 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02831064 0,04643177 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02831064 0,04640014 ! nerve development GO:0021675 28 18 0,000 0,02831064 0,04636855 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02831064 0,04633701 ! protein secretion GO:0009306 39 19 0,000 0,02986023 0,04884005 ! positive regulation of translation GO:0045727 30 19 0,000 0,02986023 0,04880687 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02986023 0,04877374 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02986023 0,04874065 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02986023 0,0487076 ! skin development GO:0043588 36 19 0,000 0,02986023 0,0486746 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02986023 0,04864165 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02986023 0,04860874 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02986023 0,04857587 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02986023 0,04854305 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02986023 0,04851027 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02986023 0,04847754 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02986023 0,04844485 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02986023 0,04841221 ! cerebral cortex development GO:0021987 36 19 0,000 0,02986023 0,04837961 ! pigmentation during development GO:0048066 41 19 0,000 0,02986023 0,04834705 ! response to vitamin A GO:0033189 27 19 0,000 0,02986023 0,04831453 ! heme metabolic process GO:0042168 36 19 0,000 0,02986023 0,04828207 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02986023 0,04824964 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02986023 0,04821726 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02986023 0,04818492 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02986023 0,04815262 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02986023 0,04812037 ! peptide cross-linking GO:0018149 37 19 0,000 0,02986023 0,04808816 ! protein export from nucleus GO:0006611 36 19 0,000 0,02986023 0,048056 ! heart process GO:0003015 30 19 0,000 0,02986023 0,04802387 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02986023 0,04799179 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02986023 0,04795976 ! visual learning GO:0008542 36 19 0,000 0,02986023 0,04792776 ! cellular pigmentation GO:0033059 36 19 0,000 0,02986023 0,04789581 ! G1 phase GO:0051318 40 19 0,000 0,02986023 0,0478639 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02986023 0,04783203 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02986023 0,04780021 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02986023 0,04776843 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02986023 0,04773669 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02986023 0,04770499 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02986023 0,04767333 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02986023 0,04764172 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02986023 0,04761015 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02986023 0,04757862 ! cilium assembly GO:0042384 37 19 0,000 0,02986023 0,04754713 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02986023 0,04751568 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0314074 0,04994462 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0314074 0,04991163 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0314074 0,04987868 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0314074 0,04984578 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0314074 0,04981292 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,0314074 0,04978011 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0314074 0,04974734 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0314074 0,04971461 ! response to vitamin GO:0033273 31 20 0,000 0,0314074 0,04968192 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0314074 0,04964928 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,0314074 0,04961668 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0314074 0,04958412 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0314074 0,04955161 ! response to alkaloid GO:0043279 38 20 0,000 0,0314074 0,04951914 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0314074 0,04948671 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0314074 0,04945432 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,0314074 0,04942198 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0314074 0,04938968 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0314074 0,04935742 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0314074 0,0493252 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0314074 0,04929302 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,0314074 0,04926089 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0314074 0,0492288 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0314074 0,04919675 ! body fluid secretion GO:0007589 31 20 0,000 0,0314074 0,04916474 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0314074 0,04913277 ! peptide secretion GO:0002790 35 20 0,000 0,0314074 0,04910085 ! stem cell differentiation GO:0048863 53 20 0,000 0,0314074 0,04906896 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0314074 0,04903712 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0314074 0,04900532 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0314074 0,04897356 ! sensory perception of pain GO:0019233 30 20 0,000 0,0314074 0,04894184 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0314074 0,04891016 ! diencephalon development GO:0021536 34 20 0,000 0,0314074 0,04887853 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0314074 0,04884693 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0314074 0,04881538 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0314074 0,04878386 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0314074 0,04875239 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0314074 0,04872096 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0314074 0,04868956 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0314074 0,04865821 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0314074 0,0486269 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0314074 0,04859563 ! regulation of glucose import GO:0046324 29 20 0,000 0,0314074 0,0485644 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0314074 0,04853321 ! actin filament-based movement GO:0030048 43 20 0,000 0,0314074 0,04850206 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0314074 0,04847095 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0314074 0,04843987 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0314074 0,04840884 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0314074 0,04837785 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0314074 0,0483469 ! regulation of cell killing GO:0031341 42 21 0,000 0,03295215 0,05069238 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03295215 0,05065999 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03295215 0,05062764 ! hormone secretion GO:0046879 38 21 0,000 0,03295215 0,05059533 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03295215 0,05056306 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03295215 0,05053084 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03295215 0,05049865 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03295215 0,05046651 ! axis specification GO:0009798 38 21 0,000 0,03295215 0,0504344 ! ovarian follicle development GO:0001541 35 21 0,000 0,03295215 0,05040234 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03295215 0,05037032 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03295215 0,05033834 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03295215 0,0503064 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03295215 0,0502745 ! cell aging GO:0007569 44 21 0,000 0,03295215 0,05024264 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03295215 0,05021082 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03295215 0,05017904 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03295215 0,0501473 ! cytolysis GO:0019835 24 21 0,000 0,03295215 0,0501156 ! vasodilation GO:0042311 39 21 0,000 0,03295215 0,05008394 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03295215 0,05005232 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03295215 0,05002074 ! oogenesis GO:0048477 36 21 0,000 0,03295215 0,04998921 ! DNA modification GO:0006304 34 21 0,000 0,03295215 0,04995771 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03295215 0,04992625 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03295215 0,04989483 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03295215 0,04986345 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03295215 0,04983211 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03295215 0,0498008 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03295215 0,04976954 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03295215 0,04973832 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03295215 0,04970713 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03295215 0,04967599 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03295215 0,04964488 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03295215 0,04961382 ! collagen catabolic process GO:0030574 28 21 0,000 0,03295215 0,04958279 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03295215 0,0495518 ! gut development GO:0048565 39 21 0,000 0,03295215 0,04952085 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03449449 0,05180634 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03449449 0,05177402 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03449449 0,05174174 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03449449 0,0517095 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03449449 0,05167731 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03449449 0,05164515 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03449449 0,05161303 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03449449 0,05158095 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03449449 0,05154891 ! regeneration GO:0031099 41 22 0,000 0,03449449 0,05151692 ! keratinization GO:0031424 28 22 0,000 0,03449449 0,05148496 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03449449 0,05145304 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03449449 0,05142116 ! sensory perception of taste GO:0050909 28 22 0,000 0,03449449 0,05138932 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03449449 0,05135752 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03449449 0,05132576 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03449449 0,05129404 ! vacuolar transport GO:0007034 36 22 0,000 0,03449449 0,05126236 ! lysosome organization GO:0007040 41 22 0,000 0,03449449 0,05123071 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03449449 0,05119911 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03449449 0,05116754 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03449449 0,05113602 ! fucose metabolic process GO:0006004 39 22 0,000 0,03449449 0,05110453 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03449449 0,05107308 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03449449 0,05104167 ! ureteric bud development GO:0001657 43 22 0,000 0,03449449 0,0510103 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03449449 0,05097896 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03449449 0,05094767 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03449449 0,05091641 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,03449449 0,05088519 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03449449 0,05085402 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03449449 0,05082287 ! sarcomere organization GO:0045214 30 22 0,000 0,03449449 0,05079177 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,03449449 0,05076071 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03449449 0,05072968 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03449449 0,05069869 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03449449 0,05066774 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03449449 0,05063682 ! protein stabilization GO:0050821 39 22 0,000 0,03449449 0,05060595 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03603443 0,05283293 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03603443 0,05280075 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03603443 0,05276861 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03603443 0,05273651 ! gluconeogenesis GO:0006094 33 23 0,000 0,03603443 0,05270446 ! viral genome replication GO:0019079 41 23 0,000 0,03603443 0,05267244 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03603443 0,05264046 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03603443 0,05260851 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03603443 0,05257661 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03603443 0,05254475 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03603443 0,05251292 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03603443 0,05248113 ! visual behavior GO:0007632 42 23 0,000 0,03603443 0,05244938 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03603443 0,05241767 ! response to ethanol GO:0045471 46 23 0,000 0,03603443 0,052386 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03603443 0,05235437 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03603443 0,05232277 ! peroxisome organization GO:0007031 37 23 0,000 0,03603443 0,05229121 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03603443 0,05225969 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03603443 0,05222821 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03603443 0,05219677 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03603443 0,05216536 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03603443 0,05213399 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03603443 0,05210266 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03603443 0,05207137 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03603443 0,05204011 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03603443 0,0520089 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03603443 0,05197772 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03603443 0,05194657 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03603443 0,05191547 ! fatty acid transport GO:0015908 44 23 0,000 0,03603443 0,0518844 ! platelet activation GO:0030168 37 23 0,000 0,03603443 0,05185337 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03603443 0,05182237 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03603443 0,05179142 ! hormone transport GO:0009914 40 23 0,000 0,03603443 0,0517605 ! cell-cell recognition GO:0009988 25 23 0,000 0,03603443 0,05172961 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03603443 0,05169877 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03603443 0,05166796 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03603443 0,05163718 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03603443 0,05160645 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03603443 0,05157575 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03757195 0,05374442 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03757195 0,05371249 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03757195 0,05368059 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03757195 0,05364874 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03757195 0,05361692 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03757195 0,05358513 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03757195 0,05355339 ! vesicle docking GO:0048278 47 24 0,000 0,03757195 0,05352168 ! spinal cord development GO:0021510 47 24 0,000 0,03757195 0,05349001 ! vacuole organization GO:0007033 43 24 0,000 0,03757195 0,05345838 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03757195 0,05342679 ! digestive system process GO:0022600 39 24 0,000 0,03757195 0,05339523 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03757195 0,05336371 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03757195 0,05333222 ! regulation of behavior GO:0050795 43 24 0,000 0,03757195 0,05330078 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03757195 0,05326937 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03757195 0,053238 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03757195 0,05320666 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03757195 0,05317537 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03757195 0,0531441 ! membrane depolarization GO:0051899 39 24 0,000 0,03757195 0,05311288 ! pallium development GO:0021543 49 24 0,000 0,03757195 0,05308169 ! pentose metabolic process GO:0019321 35 24 0,000 0,03757195 0,05305054 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03757195 0,05301943 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03757195 0,05298835 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03757195 0,05295731 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03757195 0,0529263 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03757195 0,05289533 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03757195 0,0528644 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03757195 0,0528335 ! regulation of amine transport GO:0051952 40 24 0,000 0,03757195 0,05280264 ! protein tetramerization GO:0051262 52 24 0,000 0,03757195 0,05277182 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03910708 0,05489594 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03910708 0,05486393 ! myelination GO:0042552 45 25 0,000 0,03910708 0,05483195 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03910708 0,05480002 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03910708 0,05476812 ! phototransduction GO:0007602 33 25 0,000 0,03910708 0,05473626 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03910708 0,05470444 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03910708 0,05467265 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03910708 0,0546409 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03910708 0,05460919 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03910708 0,05457751 ! receptor metabolic process GO:0043112 46 25 0,000 0,03910708 0,05454587 ! chromosome condensation GO:0030261 45 25 0,000 0,03910708 0,05451427 ! response to starvation GO:0042594 42 25 0,000 0,03910708 0,05448271 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03910708 0,05445118 ! neural crest cell development GO:0014032 54 25 0,000 0,03910708 0,05441968 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03910708 0,05438823 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03910708 0,05435681 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03910708 0,05432542 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03910708 0,05429408 ! interaction with host GO:0051701 62 25 0,000 0,03910708 0,05426276 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03910708 0,05423149 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03910708 0,05420025 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03910708 0,05416905 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03910708 0,05413788 ! immunoglobulin production GO:0002377 55 25 0,000 0,03910708 0,05410675 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03910708 0,05407565 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03910708 0,05404459 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03910708 0,05401357 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03910708 0,05398258 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03910708 0,05395162 ! telomere organization GO:0032200 43 25 0,000 0,03910708 0,05392071 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03910708 0,05388982 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03910708 0,05385898 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04063981 0,05593786 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04063981 0,05590588 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04063981 0,05587393 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04063981 0,05584202 ! initiation of viral infection GO:0019059 57 26 0,000 0,04063981 0,05581015 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04063981 0,05577831 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04063981 0,05574651 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04063981 0,05571475 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04063981 0,05568302 ! molting cycle process GO:0022404 50 26 0,000 0,04063981 0,05565133 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04063981 0,05561967 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04063981 0,05558805 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,04063981 0,05555646 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04063981 0,05552492 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04063981 0,0554934 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,04063981 0,05546193 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,04063981 0,05543049 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04063981 0,05539908 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04063981 0,05536771 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,04063981 0,05533638 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04063981 0,05530508 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04063981 0,05527381 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04063981 0,05524259 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04063981 0,05521139 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04063981 0,05518024 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04063981 0,05514911 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04063981 0,05511803 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04063981 0,05508697 ! blastocyst development GO:0001824 49 26 0,000 0,04063981 0,05505596 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04063981 0,05502497 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04063981 0,05499403 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04063981 0,05496311 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04217014 0,05700077 ! neuron fate commitment GO:0048663 48 27 0,000 0,04217014 0,05696876 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04217014 0,05693679 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04217014 0,05690486 ! iron ion transport GO:0006826 59 27 0,000 0,04217014 0,05687296 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04217014 0,0568411 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04217014 0,05680927 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04217014 0,05677748 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04217014 0,05674573 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04217014 0,05671401 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04217014 0,05668233 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04217014 0,05665068 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04217014 0,05661906 ! autophagy GO:0006914 41 27 0,000 0,04217014 0,05658749 ! male gonad development GO:0008584 44 27 0,000 0,04217014 0,05655594 ! response to toxin GO:0009636 47 27 0,000 0,04217014 0,05652444 ! primary neural tube formation GO:0014020 51 27 0,000 0,04217014 0,05649296 ! base-excision repair GO:0006284 41 27 0,000 0,04217014 0,05646153 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04217014 0,05643012 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04217014 0,05639876 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04217014 0,05636742 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04217014 0,05633613 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04217014 0,05630486 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04217014 0,05627363 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04217014 0,05624244 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04217014 0,05621128 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04369809 0,05821572 ! circadian rhythm GO:0007623 50 28 0,000 0,04369809 0,05818351 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04369809 0,05815133 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04369809 0,05811918 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04369809 0,05808707 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04369809 0,05805499 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04369809 0,05802296 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04369809 0,05799095 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04369809 0,05795898 ! synaptogenesis GO:0007416 42 28 0,000 0,04369809 0,05792705 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04369809 0,05789515 ! lipid oxidation GO:0034440 43 28 0,000 0,04369809 0,05786329 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04369809 0,05783146 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04369809 0,05779967 ! translational initiation GO:0006413 65 29 0,000 0,04522364 0,05978466 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04522364 0,05975183 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04522364 0,05971904 ! regulation of pH GO:0006885 43 29 0,000 0,04522364 0,05968628 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04522364 0,05965356 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04522364 0,05962087 ! catechol metabolic process GO:0009712 54 29 0,000 0,04522364 0,05958822 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04522364 0,0595556 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04522364 0,05952302 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04522364 0,05949048 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04522364 0,05945797 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04522364 0,0594255 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04522364 0,05939306 ! cell fate determination GO:0001709 60 29 0,000 0,04522364 0,05936066 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04522364 0,05932829 ! detection of light stimulus GO:0009583 38 29 0,000 0,04522364 0,05929596 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04522364 0,05926366 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04522364 0,0592314 ! tissue homeostasis GO:0001894 48 29 0,000 0,04522364 0,05919918 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04522364 0,05916699 ! phenol metabolic process GO:0018958 55 30 0,000 0,04674682 0,06112655 ! zinc ion transport GO:0006829 45 30 0,000 0,04674682 0,06109334 ! membrane docking GO:0022406 61 30 0,000 0,04674682 0,06106018 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04674682 0,06102704 ! cell junction assembly GO:0034329 78 30 0,000 0,04674682 0,06099395 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04674682 0,06096089 ! acute-phase response GO:0006953 49 30 0,000 0,04674682 0,06092787 ! myofibril assembly GO:0030239 47 30 0,000 0,04674682 0,06089488 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04674682 0,06086193 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04674682 0,06082901 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04674682 0,06079613 ! phospholipid transport GO:0015914 51 30 0,000 0,04674682 0,06076329 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04674682 0,06073048 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04674682 0,0606977 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04674682 0,06066496 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04674682 0,06063226 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04674682 0,06059959 ! eye morphogenesis GO:0048592 60 30 0,000 0,04674682 0,06056696 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04674682 0,06053436 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04826761 0,06247008 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04826761 0,06243649 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04826761 0,06240294 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04826761 0,06236943 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04826761 0,06233595 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04826761 0,06230251 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04826761 0,0622691 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04826761 0,06223573 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04826761 0,0622024 ! ovulation cycle process GO:0022602 49 31 0,000 0,04826761 0,0621691 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04826761 0,06213584 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04826761 0,06210261 ! peptide transport GO:0015833 55 31 0,000 0,04826761 0,06206942 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04826761 0,06203626 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04826761 0,06200314 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04826761 0,06197005 ! mesoderm formation GO:0001707 69 31 0,000 0,04826761 0,061937 ! natural killer cell activation GO:0030101 45 31 0,000 0,04826761 0,06190398 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04826761 0,061871 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04826761 0,06183806 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04826761 0,06180515 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04826761 0,06177227 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04826761 0,06173943 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04978603 0,06364782 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04978603 0,06361402 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04978603 0,06358025 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04978603 0,06354652 ! cholesterol transport GO:0030301 56 32 0,000 0,04978603 0,06351283 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04978603 0,06347917 ! spliceosome assembly GO:0000245 67 32 0,000 0,04978603 0,06344555 ! spindle organization GO:0007051 46 32 0,000 0,04978603 0,06341196 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04978603 0,06337841 ! metanephros development GO:0001656 74 32 0,000 0,04978603 0,06334489 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04978603 0,06331141 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04978603 0,06327797 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04978603 0,06324456 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04978603 0,06321118 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04978603 0,06317784 ! muscle cell development GO:0055001 49 32 0,000 0,04978603 0,06314454 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04978603 0,06311127 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04978603 0,06307804 ! ovulation cycle GO:0042698 51 32 0,000 0,04978603 0,06304484 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04978603 0,06301167 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04978603 0,06297854 ! hindbrain development GO:0030902 61 32 0,000 0,04978603 0,06294545 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04978603 0,06291239 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04978603 0,06287937 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04978603 0,06284638 ! gene silencing GO:0016458 65 32 0,000 0,04978603 0,06281342 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,05130208 0,06469224 ! post-embryonic development GO:0009791 69 33 0,000 0,05130208 0,06465836 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,05130208 0,0646245 ! protein targeting to membrane GO:0006612 68 33 0,000 0,05130208 0,06459069 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05130208 0,0645569 ! ceramide metabolic process GO:0006672 64 33 0,000 0,05130208 0,06452316 ! formation of primary germ layer GO:0001704 72 33 0,000 0,05130208 0,06448945 ! cell fate specification GO:0001708 52 33 0,000 0,05130208 0,06445577 ! sterol transport GO:0015918 57 33 0,000 0,05130208 0,06442213 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05130208 0,06438852 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05130208 0,06435495 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05130208 0,06432142 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05130208 0,06428792 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05130208 0,06425445 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05281576 0,06611587 ! glial cell differentiation GO:0010001 63 34 0,000 0,05281576 0,06608149 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05281576 0,06604715 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05281576 0,06601284 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05281576 0,06597856 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05281576 0,06594432 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05281576 0,06591012 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05281576 0,06587595 ! mismatch repair GO:0006298 46 34 0,000 0,05281576 0,06584182 ! spermatid development GO:0007286 63 34 0,000 0,05281576 0,06580772 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05281576 0,06577366 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05281576 0,06573963 ! placenta development GO:0001890 53 34 0,000 0,05281576 0,06570564 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,05281576 0,06567169 ! regulation of muscle development GO:0048634 70 35 0,000 0,05432707 0,06751598 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05432707 0,06748112 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05432707 0,0674463 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05432707 0,06741152 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05432707 0,06737677 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05432707 0,06734206 ! odontogenesis GO:0042476 66 35 0,000 0,05432707 0,06730738 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05432707 0,06727274 ! female gonad development GO:0008585 58 35 0,000 0,05432707 0,06723813 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,05432707 0,06720356 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,05432707 0,06716903 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05432707 0,06713453 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,05432707 0,06710007 ! cytokine production GO:0001816 59 35 0,000 0,05432707 0,06706564 ! neural tube formation GO:0001841 67 35 0,000 0,05432707 0,06703125 ! vesicle localization GO:0051648 64 35 0,000 0,05432707 0,06699689 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05583602 0,06882247 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05583602 0,06878724 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05583602 0,06875203 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05583602 0,06871686 ! cell junction organization GO:0034330 86 36 0,000 0,05583602 0,06868173 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05583602 0,06864664 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05583602 0,06861158 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05583602 0,06857655 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,05583602 0,06854157 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05583602 0,06850661 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,05583602 0,0684717 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05583602 0,06843682 ! aerobic respiration GO:0009060 55 36 0,000 0,05583602 0,06840197 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,05583602 0,06836716 ! embryonic organ development GO:0048568 57 36 0,000 0,05583602 0,06833239 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05583602 0,06829765 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05734262 0,07010485 ! meiosis I GO:0007127 65 37 0,000 0,05734262 0,07006924 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05734262 0,07003367 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05734262 0,06999814 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05734262 0,06996265 ! organic anion transport GO:0015711 68 37 0,000 0,05734262 0,06992719 ! tissue remodeling GO:0048771 76 37 0,000 0,05734262 0,06989176 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05734262 0,06985637 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05734262 0,06982102 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05734262 0,0697857 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,05734262 0,06975042 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05734262 0,06971518 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05734262 0,06967997 ! glycogen metabolic process GO:0005977 61 37 0,000 0,05734262 0,06964479 ! pigment metabolic process GO:0042440 80 37 0,000 0,05734262 0,06960966 ! spermatid differentiation GO:0048515 66 37 0,000 0,05734262 0,06957455 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,05734262 0,06953948 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,05884686 0,07132773 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,05884686 0,07129181 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05884686 0,07125593 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05884686 0,07122009 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05884686 0,07118428 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,05884686 0,07114851 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,05884686 0,07111278 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05884686 0,07107708 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05884686 0,07104141 ! lipid homeostasis GO:0055088 67 38 0,000 0,05884686 0,07100579 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05884686 0,0709702 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,05884686 0,07093464 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05884686 0,07089912 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05884686 0,07086363 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,05884686 0,07082818 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05884686 0,07079277 ! glucan metabolic process GO:0044042 62 38 0,000 0,05884686 0,07075739 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,06034875 0,07252702 ! mammary gland development GO:0030879 86 39 0,000 0,06034875 0,07249081 ! learning GO:0007612 77 39 0,000 0,06034875 0,07245463 ! ear morphogenesis GO:0042471 60 39 0,000 0,06034875 0,0724185 ! organic ether metabolic process GO:0018904 55 39 0,000 0,06034875 0,0723824 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06034875 0,07234633 ! segmentation GO:0035282 67 39 0,000 0,06034875 0,0723103 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06034875 0,07227431 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,06034875 0,07223835 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06034875 0,07220243 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06034875 0,07216654 ! RNA modification GO:0009451 57 39 0,000 0,06034875 0,07213069 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,06034875 0,07209488 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06184829 0,07384962 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06184829 0,07381299 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06184829 0,07377639 ! feeding behavior GO:0007631 59 40 0,000 0,06184829 0,07373984 ! negative regulation of binding GO:0051100 72 40 0,000 0,06184829 0,07370331 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06184829 0,07366683 ! mesenchymal cell development GO:0014031 87 40 0,000 0,06184829 0,07363037 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06184829 0,07359396 ! maintenance of protein location GO:0045185 91 40 0,000 0,06184829 0,07355758 ! cytokinesis GO:0000910 72 40 0,000 0,06184829 0,07352124 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06334549 0,07526383 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06334549 0,07522668 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06334549 0,07518957 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06334549 0,07515249 ! gliogenesis GO:0042063 88 41 0,000 0,06334549 0,07511545 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06334549 0,07507845 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06334549 0,07504148 ! T cell differentiation GO:0030217 81 41 0,000 0,06334549 0,07500455 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06334549 0,07496766 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06334549 0,0749308 ! female gamete generation GO:0007292 61 41 0,000 0,06334549 0,07489398 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06334549 0,0748572 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06484035 0,0765861 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06484035 0,07654852 ! regulation of tube size GO:0035150 71 42 0,000 0,06484035 0,07651098 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06484035 0,07647347 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06484035 0,076436 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,06484035 0,07639857 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06484035 0,07636118 ! neuron migration GO:0001764 79 42 0,000 0,06484035 0,07632382 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06484035 0,0762865 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06484035 0,07624921 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,06633288 0,07796624 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,06633288 0,07792817 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,06633288 0,07789014 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,06633288 0,07785215 ! glucose transport GO:0015758 65 43 0,000 0,06633288 0,07781419 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06633288 0,07777627 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06633288 0,07773838 ! neural tube development GO:0021915 77 43 0,000 0,06633288 0,07770053 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,06633288 0,07766272 ! striated muscle contraction GO:0006941 77 43 0,000 0,06633288 0,07762495 ! phagocytosis GO:0006909 90 43 0,000 0,06633288 0,07758721 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06633288 0,07754951 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06782307 0,07925318 ! hexose transport GO:0008645 67 44 0,000 0,06782307 0,07921471 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,06782307 0,07917627 ! male sex differentiation GO:0046661 76 44 0,000 0,06782307 0,07913788 ! double-strand break repair GO:0006302 81 44 0,000 0,06782307 0,07909951 ! biopolymer methylation GO:0043414 84 44 0,000 0,06782307 0,07906119 ! B cell differentiation GO:0030183 107 44 0,000 0,06782307 0,0790229 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,06782307 0,07898466 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06782307 0,07894644 ! developmental growth GO:0048589 82 44 0,000 0,06782307 0,07890827 ! maintenance of location in cell GO:0051651 97 44 0,000 0,06782307 0,07887013 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06931093 0,0805614 ! glycolysis GO:0006096 65 45 0,000 0,06931093 0,0805225 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,06931093 0,08048364 ! leukocyte migration GO:0050900 68 45 0,000 0,06931093 0,08044481 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06931093 0,08040603 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,06931093 0,08036728 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,06931093 0,08032856 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06931093 0,08028989 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,06931093 0,08025125 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06931093 0,08021265 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06931093 0,08017408 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06931093 0,08013556 ! cell growth GO:0016049 84 45 0,000 0,06931093 0,08009707 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07079647 0,08177451 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,07079647 0,08173527 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,07079647 0,08169607 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07079647 0,0816569 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,07079647 0,08161778 ! pigmentation GO:0043473 100 46 0,000 0,07079647 0,08157869 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,07079647 0,08153964 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07227968 0,08320809 ! endosome transport GO:0016197 108 47 0,000 0,07227968 0,0831683 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07227968 0,08312854 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07227968 0,08308883 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07227968 0,08304915 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,07227968 0,08300951 ! JNK cascade GO:0007254 91 47 0,000 0,07227968 0,0829699 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,07227968 0,08293034 ! methylation GO:0032259 90 47 0,000 0,07227968 0,08289081 ! protein homooligomerization GO:0051260 76 47 0,000 0,07227968 0,08285132 ! mitochondrial transport GO:0006839 82 48 0,000 0,07376058 0,08450855 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07376058 0,08446833 ! cellular component disassembly GO:0022411 86 48 0,000 0,07376058 0,08442814 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07376058 0,08438799 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,07376058 0,08434789 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07376058 0,08430782 ! activation of caspase activity GO:0006919 84 48 0,000 0,07376058 0,08426778 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07376058 0,08422779 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07376058 0,08418783 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07376058 0,08414792 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07376058 0,08410803 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07523916 0,0857534 ! regulation of action potential GO:0001508 95 49 0,000 0,07523916 0,08571279 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07523916 0,08567223 ! regulation of ion transport GO:0043269 77 49 0,000 0,07523916 0,0856317 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07523916 0,08559122 ! peptide metabolic process GO:0006518 76 49 0,000 0,07523916 0,08555077 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07523916 0,08551036 ! endocrine system development GO:0035270 104 49 0,000 0,07523916 0,08546998 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,07523916 0,08542965 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07523916 0,08538935 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07523916 0,08534909 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07671543 0,08698272 ! neuromuscular process GO:0050905 99 50 0,000 0,07671543 0,08694175 ! regulation of ossification GO:0030278 117 50 0,000 0,07671543 0,08690081 ! inner ear development GO:0048839 79 50 0,000 0,07671543 0,08685992 ! histone modification GO:0016570 91 50 0,000 0,07671543 0,08681906 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,07671543 0,08677825 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07671543 0,08673747 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07671543 0,08669673 ! positive regulation of binding GO:0051099 78 51 0,000 0,0781894 0,08832098 ! viral infectious cycle GO:0019058 99 51 0,000 0,0781894 0,08827953 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,0781894 0,08823813 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,0781894 0,08819676 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,0781894 0,08815543 ! excretion GO:0007588 83 51 0,000 0,0781894 0,08811414 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,0781894 0,08807289 ! chromatin remodeling GO:0006338 109 51 0,000 0,0781894 0,08803167 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,0781894 0,0879905 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,0781894 0,08794936 ! vesicle organization GO:0016050 107 51 0,000 0,0781894 0,08790826 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,0781894 0,08786721 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,0781894 0,08782618 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,0781894 0,0877852 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,07966106 0,08939576 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,07966106 0,08935408 ! membrane fusion GO:0006944 110 52 0,000 0,07966106 0,08931244 ! positive regulation of growth GO:0045927 90 52 0,000 0,07966106 0,08927084 ! covalent chromatin modification GO:0016569 101 52 0,000 0,07966106 0,08922928 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,07966106 0,08918776 ! amino acid activation GO:0043038 92 52 0,000 0,07966106 0,08914628 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,07966106 0,08910483 ! synapse organization GO:0050808 85 52 0,000 0,07966106 0,08906343 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08113041 0,09066409 ! RNA catabolic process GO:0006401 93 53 0,000 0,08113041 0,09062199 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08113041 0,09057994 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08113041 0,09053793 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,08113041 0,09049596 ! cell maturation GO:0048469 100 53 0,000 0,08113041 0,09045402 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,08113041 0,09041212 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,08113041 0,09037027 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,08259748 0,09196184 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08259748 0,0919193 ! cell recognition GO:0008037 85 54 0,000 0,08259748 0,0918768 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,08259748 0,09183435 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08259748 0,09179193 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08259748 0,09174955 ! chloride transport GO:0006821 90 55 0,000 0,08406224 0,09333353 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,08406224 0,09329048 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,08406224 0,09324747 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,08406224 0,0932045 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08406224 0,09316157 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08406224 0,09311867 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08406224 0,09307582 ! gastrulation GO:0007369 112 55 0,000 0,08406224 0,09303301 ! heart morphogenesis GO:0003007 97 55 0,000 0,08406224 0,09299023 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08406224 0,0929475 ! RNA elongation GO:0006354 79 55 0,000 0,08406224 0,0929048 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08406224 0,09286215 ! regulation of actin filament length GO:0030832 105 56 0,000 0,08552472 0,09443436 ! sensory perception of smell GO:0007608 80 56 0,000 0,08552472 0,09439105 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08552472 0,09434777 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08552472 0,09430453 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08552472 0,09426133 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08552472 0,09421817 ! proton transport GO:0015992 94 56 0,000 0,08552472 0,09417505 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,08552472 0,09413197 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,08698491 0,09569534 ! muscle fiber development GO:0048747 112 57 0,000 0,08698491 0,0956516 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,08698491 0,0956079 ! lipid modification GO:0030258 97 57 0,000 0,08698491 0,09556425 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,08698491 0,09552063 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,08698491 0,09547705 ! maintenance of location GO:0051235 118 57 0,000 0,08698491 0,09543352 ! hydrogen transport GO:0006818 97 58 0,000 0,08844282 0,0969888 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,08844282 0,09694461 ! regulation of endocytosis GO:0030100 91 58 0,000 0,08844282 0,09690047 ! adult behavior GO:0030534 99 58 0,000 0,08844282 0,09685636 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,08844282 0,0968123 ! positive regulation of secretion GO:0051047 95 59 0,000 0,08989845 0,09836092 ! regulation of cellular component size GO:0032535 109 59 0,000 0,08989845 0,09831621 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,08989845 0,09827155 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,08989845 0,09822692 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,08989845 0,09818233 ! DNA catabolic process GO:0006308 86 59 0,000 0,08989845 0,09813778 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,08989845 0,09809327 ! establishment of organelle localization GO:0051656 109 59 0,000 0,08989845 0,09804881 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0913518 0,09958878 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,0913518 0,09954368 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0913518 0,09949861 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0913518 0,09945359 ! camera-type eye development GO:0043010 116 60 0,000 0,0913518 0,09940861 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,0913518 0,09936367 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0913518 0,09931877 ! kidney development GO:0001822 122 60 0,000 0,0913518 0,09927391 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,09280288 0,1008053 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,09280288 0,10075981 ! mesoderm development GO:0007498 119 61 0,000 0,09280288 0,10071436 ! tRNA processing GO:0008033 89 61 0,000 0,09280288 0,10066895 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,09280288 0,10062359 ! ear development GO:0043583 103 62 0,000 0,09425169 0,10214846 ! viral reproductive process GO:0022415 126 62 0,000 0,09425169 0,10210247 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09425169 0,10205651 ! gonad development GO:0008406 98 62 0,000 0,09425169 0,10201061 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,09425169 0,10196474 ! regulation of mitosis GO:0007088 105 63 0,000 0,09569824 0,10348313 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09569824 0,10343664 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,09569824 0,10339019 ! detection of external stimulus GO:0009581 91 63 0,000 0,09569824 0,10334379 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09569824 0,10329743 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,09569824 0,1032511 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,09714252 0,1047624 ! cell redox homeostasis GO:0045454 102 64 0,000 0,09714252 0,10471546 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,09714252 0,10466857 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,09714252 0,10462171 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,09714252 0,1045749 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,09714252 0,10452813 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,09858455 0,10603237 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,09858455 0,10598499 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,09858455 0,10593766 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,09858455 0,10589037 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,09858455 0,10584311 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10002432 0,10734099 ! actin filament organization GO:0007015 148 66 0,000 0,10002432 0,10729314 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10002432 0,10724532 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10002432 0,10719755 ! secondary metabolic process GO:0019748 116 66 0,000 0,10002432 0,10714982 ! developmental maturation GO:0021700 116 66 0,000 0,10002432 0,10710214 ! cell projection assembly GO:0030031 120 66 0,000 0,10002432 0,10705449 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,10146183 0,10854476 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,10146183 0,10849652 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,10146183 0,10844832 ! activation of MAPK activity GO:0000187 115 67 0,000 0,10146183 0,10840016 ! lung development GO:0030324 144 67 0,000 0,10146183 0,10835205 ! chromosome segregation GO:0007059 113 67 0,000 0,10146183 0,10830398 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,10146183 0,10825595 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,10146183 0,10820797 ! hexose catabolic process GO:0019320 104 67 0,000 0,10146183 0,10816002 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,10146183 0,10811212 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,10146183 0,10806426 ! adaptive immune response GO:0002250 119 67 0,000 0,10146183 0,10801645 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,10146183 0,10796867 ! amino acid transport GO:0006865 125 68 0,000 0,1028971 0,10944758 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,1028971 0,10939922 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,1028971 0,1093509 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,1028971 0,10930262 ! viral reproduction GO:0016032 134 68 0,000 0,1028971 0,10925438 ! regulation of lipase activity GO:0060191 130 68 0,000 0,1028971 0,10920619 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,1028971 0,10915804 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,10433013 0,11062948 ! negative regulation of cell size GO:0045792 134 69 0,000 0,10433013 0,11058074 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,10433013 0,11053205 ! urogenital system development GO:0001655 137 69 0,000 0,10433013 0,1104834 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,10433013 0,11043479 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,10433013 0,11038623 ! antigen processing and presentation GO:0019882 104 69 0,000 0,10433013 0,11033771 ! appendage morphogenesis GO:0035107 135 70 0,000 0,10576091 0,11180173 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,10576091 0,11175263 ! amine catabolic process GO:0009310 117 71 0,000 0,10718945 0,11321239 ! reproductive structure development GO:0048608 113 71 0,000 0,10718945 0,11316271 ! appendage development GO:0048736 136 71 0,000 0,10718945 0,11311308 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,10718945 0,11306349 ! B cell activation GO:0042113 160 71 0,000 0,10718945 0,11301395 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,10718945 0,11296444 ! regulation of immune effector process GO:0002697 137 71 0,000 0,10718945 0,11291498 ! acute inflammatory response GO:0002526 113 72 0,000 0,10861576 0,11436741 ! regulation of caspase activity GO:0043281 122 72 0,000 0,10861576 0,11431738 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,10861576 0,11426739 ! carbohydrate transport GO:0008643 110 72 0,000 0,10861576 0,11421745 ! respiratory system development GO:0060541 153 72 0,000 0,10861576 0,11416755 ! learning or memory GO:0007611 147 73 0,000 0,11003984 0,11561391 ! regulation of blood pressure GO:0008217 125 73 0,000 0,11003984 0,11556345 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,11003984 0,11551303 ! axon guidance GO:0007411 139 73 0,000 0,11003984 0,11546265 ! fertilization GO:0009566 90 73 0,000 0,11003984 0,11541232 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,11146169 0,11685265 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,11146169 0,11680176 ! neurotransmitter transport GO:0006836 123 74 0,000 0,11146169 0,11675091 ! meiosis GO:0007126 121 74 0,000 0,11146169 0,1167001 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,11146169 0,11664934 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,11146169 0,11659862 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,11146169 0,11654795 ! organelle localization GO:0051640 136 74 0,000 0,11146169 0,11649732 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,11288132 0,11792985 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,11288132 0,11787867 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11288132 0,11782753 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11288132 0,11777643 ! meiotic cell cycle GO:0051321 122 75 0,000 0,11288132 0,11772538 ! rhythmic process GO:0048511 128 75 0,000 0,11288132 0,11767437 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,11288132 0,11762341 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,11429872 0,1190488 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,11429872 0,11899729 ! defense response to bacterium GO:0042742 89 76 0,000 0,11429872 0,11894582 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,11429872 0,11889439 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,11429872 0,11884301 ! regulation of catabolic process GO:0009894 161 76 0,000 0,11429872 0,11879168 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,11571391 0,12021057 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,11571391 0,12015868 ! blood coagulation GO:0007596 146 78 0,000 0,11712689 0,12157346 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,11712689 0,12152104 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,11712689 0,12146866 ! protein oligomerization GO:0051259 139 78 0,000 0,11712689 0,12141632 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,11853765 0,12282583 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,11853765 0,12277296 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,11853765 0,12272013 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,11853765 0,12266735 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,11853765 0,12261461 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1199462 0,12401829 ! muscle cell differentiation GO:0042692 159 80 0,000 0,1199462 0,12396502 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1199462 0,12391179 ! protein import into nucleus GO:0006606 158 80 0,000 0,1199462 0,12385861 ! inorganic anion transport GO:0015698 138 80 0,000 0,1199462 0,12380548 ! T cell activation GO:0042110 168 81 0,000 0,12135256 0,12520337 ! response to hypoxia GO:0001666 171 81 0,000 0,12135256 0,1251497 ! digestion GO:0007586 112 81 0,000 0,12135256 0,12509608 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,12135256 0,12504251 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,12135256 0,12498898 ! nuclear import GO:0051170 161 81 0,000 0,12135256 0,12493549 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,12135256 0,12488206 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,12275671 0,12627304 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,12275671 0,12621908 ! response to drug GO:0042493 143 82 0,000 0,12275671 0,12616516 ! response to nutrient GO:0007584 125 82 0,000 0,12275671 0,12611129 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,12275671 0,12605746 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,12275671 0,12600368 ! response to oxygen levels GO:0070482 176 83 0,000 0,12415866 0,12738837 ! regulation of lyase activity GO:0051339 160 83 0,000 0,12415866 0,12733407 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,12555842 0,12871477 ! hemostasis GO:0007599 158 84 0,000 0,12555842 0,12865995 ! negative regulation of transport GO:0051051 153 84 0,000 0,12555842 0,12860518 ! negative regulation of growth GO:0045926 155 84 0,000 0,12555842 0,12855045 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,12555842 0,12849577 ! nucleosome assembly GO:0006334 122 85 0,000 0,12695599 0,1298708 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,12695599 0,1298156 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,12695599 0,12976046 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,12835137 0,13113096 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,12835137 0,1310753 ! chromatin assembly GO:0031497 124 86 0,000 0,12835137 0,13101969 ! tube morphogenesis GO:0035239 176 86 0,000 0,12835137 0,13096412 ! mitochondrion organization GO:0007005 148 86 0,000 0,12835137 0,13090861 ! amine transport GO:0015837 155 86 0,000 0,12835137 0,13085314 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,12974457 0,13221747 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,12974457 0,13216149 ! protein localization in nucleus GO:0034504 176 87 0,000 0,12974457 0,13210556 ! regulation of protein transport GO:0051223 154 87 0,000 0,12974457 0,13204968 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 0,000 0,13113559 0,13340897 ! gland development GO:0048732 206 88 0,000 0,13113559 0,13335259 ! regulation of neurological system process GO:0031644 148 88 0,000 0,13113559 0,13329625 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,13113559 0,13323996 ! cellular defense response GO:0006968 114 89 0,000 0,13252443 0,13459425 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,13252443 0,13453746 ! ossification GO:0001503 188 90 0,000 0,13391109 0,13588785 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,13391109 0,13583056 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,13391109 0,13577332 ! sex differentiation GO:0007548 145 90 0,000 0,13391109 0,13571613 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,13391109 0,13565899 ! bone development GO:0060348 189 91 0,000 0,13529559 0,13700387 ! sterol metabolic process GO:0016125 152 91 0,000 0,13529559 0,13694623 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,13529559 0,13688864 ! regulation of defense response GO:0031347 149 92 0,000 0,13667792 0,13822912 ! nucleosome organization GO:0034728 138 92 0,000 0,13667792 0,13817104 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,13667792 0,13811301 ! vitamin metabolic process GO:0006766 139 92 0,000 0,13667792 0,13805503 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,13805809 0,13939058 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,13805809 0,13933211 ! regulation of membrane potential GO:0042391 164 93 0,000 0,13805809 0,13927369 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,13805809 0,13921532 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,13943609 0,14054597 ! female pregnancy GO:0007565 164 94 0,000 0,13943609 0,14048712 ! transcription initiation GO:0006352 153 94 0,000 0,13943609 0,14042831 ! regulation of T cell activation GO:0050863 158 94 0,000 0,13943609 0,14036955 ! forebrain development GO:0030900 188 95 0,000 0,14081194 0,14169532 ! leukocyte differentiation GO:0002521 202 96 0,000 0,14218563 0,14301782 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,14218563 0,14295806 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,14218563 0,14289834 ! positive regulation of immune response GO:0050778 156 96 0,000 0,14218563 0,14283868 ! detection of stimulus GO:0051606 151 96 0,000 0,14218563 0,14277906 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,14355717 0,14409619 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,14355717 0,1440361 ! protein ubiquitination GO:0016567 217 97 0,000 0,14355717 0,14397606 ! hormone metabolic process GO:0042445 157 97 0,000 0,14355717 0,14391607 ! regulation of protein localization GO:0032880 176 97 0,000 0,14355717 0,14385613 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,14492657 0,14516791 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,14492657 0,1451075 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,14629382 0,14641553 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,14629382 0,14635465 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,14629382 0,14629382 GO:0060538|skeletal muscle organ development,