pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a1/out-0.05-06-0.01-300-run-a1//th1-pval-1e-02-02-th2-pval-1e-01-11-th3-pval-1e-01-01-run-a1/go_data/3796-4-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 9 5 2,000 2,457E-08 6,003E-05 GO:0019405|alditol catabolic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 6,973E-07 8,518E-04 ! fructose metabolic process GO:0006000 25 16 2,000 1,361E-06 1,109E-03 ! alditol metabolic process GO:0019400 44 26 2,000 6,26E-06 3,823E-03 ! sperm motility GO:0030317 37 28 2,000 7,872E-06 3,846E-03 ! hexose biosynthetic process GO:0019319 53 32 2,000 1,187E-05 4,834E-03 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,702E-05 5,941E-03 ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 1,857E-05 5,67E-03 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 1,000 1,857E-05 5,04E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,857E-05 4,536E-03 ! alcohol biosynthetic process GO:0046165 65 42 2,000 2,721E-05 6,044E-03 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 2,783E-05 5,665E-03 GO:0032862|activation of Rho GTPase activity, ! polyol metabolic process GO:0019751 77 45 2,000 3,354E-05 6,303E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 5,185E-05 9,048E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 5,185E-05 8,445E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 6,661E-05 0,0101705 ! regulation of phosphatase activity GO:0010921 28 10 1,000 8,319E-05 0,01195475 ! regulation of stress fiber formation GO:0051492 34 10 1,000 8,319E-05 0,0112906 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 1,016E-04 0,01306181 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 1,016E-04 0,01240872 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 1,676E-04 0,01950151 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 1,933E-04 0,02146002 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 2,207E-04 0,02343875 ! regulation of dephosphorylation GO:0035303 43 16 1,000 2,207E-04 0,02246213 ! alcohol catabolic process GO:0046164 142 87 2,000 2,405E-04 0,02350582 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,499E-04 0,02347816 GO:0031114|regulation of microtubule depolymerization, ! response to unfolded protein GO:0006986 139 90 2,000 2,658E-04 0,02405301 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,809E-04 0,0245047 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 3,021E-04 0,02545294 ! response to protein stimulus GO:0051789 158 96 2,000 3,214E-04 0,02617572 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,482E-04 0,0274374 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 32 20 1,000 3,482E-04 0,02657998 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,225E-04 0,03128126 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,624E-04 0,0332235 GO:0010810|regulation of cell-substrate adhesion, ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 4,624E-04 0,03227426 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,04E-04 0,03420016 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,04E-04 0,03327583 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 5,924E-04 0,03808524 ! negative regulation of protein modification process GO:0031400 66 28 1,000 6,878E-04 0,04308437 ! fat cell differentiation GO:0045444 57 28 1,000 6,878E-04 0,04200726 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 7,381E-04 0,04397974 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 8,439E-04 0,04908513 ! response to heat GO:0009408 54 31 1,000 8,439E-04 0,04794361 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 1,015E-03 0,0563781 ! regulation of microtubule-based process GO:0032886 86 37 1,000 1,202E-03 0,0652704 ! RNA export from nucleus GO:0006405 61 41 1,000 1,475E-03 0,07833997 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 1,697E-03 0,08822176 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 1,697E-03 0,0863838 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,854E-03 0,09241948 ! response to insulin stimulus GO:0032868 98 47 1,000 1,934E-03 0,09451341 ! positive regulation of cell cycle GO:0045787 96 48 1,000 2,017E-03 0,09660402 ! response to calcium ion GO:0051592 94 49 1,000 2,101E-03 0,09869128 ! response to temperature stimulus GO:0009266 84 51 1,000 2,274E-03 0,10479639 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 2,362E-03 0,10687606 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 2,362E-03 0,10493286 ! regulation of translational initiation GO:0006446 87 54 1,000 2,545E-03 0,11102472 ! response to UV GO:0009411 120 55 1,000 2,639E-03 0,1130937 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 2,734E-03 0,11515912 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,831E-03 0,11722097 ! aging GO:0007568 112 58 1,000 2,929E-03 0,11927925 ! nuclear export GO:0051168 110 59 1,000 3,03E-03 0,12133396 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 3,554E-03 0,14004127 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 4,002E-03 0,15518401 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 4,118E-03 0,15718138 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 4,118E-03 0,1547632 ! negative regulation of kinase activity GO:0033673 145 70 1,000 4,235E-03 0,15676371 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 4,475E-03 0,16315374 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 4,475E-03 0,16075442 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 4,72E-03 0,16711879 ! negative regulation of transferase activity GO:0051348 155 74 1,000 4,72E-03 0,16473138 ! eye development GO:0001654 155 75 1,000 4,845E-03 0,1667147 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 4,972E-03 0,16869457 ! positive regulation of ligase activity GO:0051351 130 77 1,000 5,1E-03 0,170671 ! regulation of actin filament-based process GO:0032970 170 79 1,000 5,361E-03 0,17697315 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 5,361E-03 0,17461351 ! negative regulation of organelle organization GO:0010639 181 80 1,000 5,493E-03 0,1765796 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 5,627E-03 0,17854225 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 5,9E-03 0,18479639 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 6,039E-03 0,1867438 ! regulation of ligase activity GO:0051340 147 84 1,000 6,039E-03 0,18440951 ! cellular respiration GO:0045333 143 88 1,000 6,608E-03 0,19930227 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,874E-03 0,20480302 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,874E-03 0,20233551 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,874E-03 0,19992676 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,874E-03 0,19757468 ! neuron fate determination GO:0048664 7 5 0,000 6,874E-03 0,1952773 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,874E-03 0,19303273 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,874E-03 0,19083918 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,874E-03 0,18869492 ! polyol transport GO:0015791 12 5 0,000 6,874E-03 0,18659831 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,874E-03 0,18454778 ! response to superoxide GO:0000303 10 5 0,000 6,874E-03 0,18254182 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,874E-03 0,18057901 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,874E-03 0,17865795 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,874E-03 0,17677734 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,874E-03 0,17493591 ! female meiosis GO:0007143 10 5 0,000 6,874E-03 0,17313245 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,874E-03 0,17136579 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,874E-03 0,16963482 ! hypothalamus development GO:0021854 9 5 0,000 6,874E-03 0,16793848 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,874E-03 0,16627572 ! cobalt ion transport GO:0006824 11 5 0,000 6,874E-03 0,16464557 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,874E-03 0,16304706 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,874E-03 0,1614793 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,874E-03 0,15994141 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,874E-03 0,15843253 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,874E-03 0,15695185 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,874E-03 0,15549859 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,874E-03 0,154072 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,874E-03 0,15267134 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,874E-03 0,15129592 ! transposition GO:0032196 9 5 0,000 6,874E-03 0,14994507 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,874E-03 0,14861812 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,874E-03 0,14731445 ! negative chemotaxis GO:0050919 16 5 0,000 6,874E-03 0,14603346 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,874E-03 0,14477455 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,874E-03 0,14353716 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,874E-03 0,14232074 ! behavioral response to pain GO:0048266 10 5 0,000 6,874E-03 0,14112477 ! clathrin coat assembly GO:0048268 15 5 0,000 6,874E-03 0,13994873 ! Notch receptor processing GO:0007220 11 5 0,000 6,874E-03 0,13879213 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,874E-03 0,13765449 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,874E-03 0,13653535 ! micturition GO:0060073 9 5 0,000 6,874E-03 0,13543426 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,874E-03 0,13435078 ! copulation GO:0007620 9 5 0,000 6,874E-03 0,13328451 ! glial cell fate commitment GO:0021781 14 5 0,000 6,874E-03 0,13223502 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,874E-03 0,13120193 ! bioluminescence GO:0008218 9 5 0,000 6,874E-03 0,13018487 ! spermidine metabolic process GO:0008216 7 5 0,000 6,874E-03 0,12918344 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,874E-03 0,12819731 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,874E-03 0,12722612 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,874E-03 0,12626953 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,874E-03 0,12532722 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,874E-03 0,12439887 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,874E-03 0,12348417 ! grooming behavior GO:0007625 6 5 0,000 6,874E-03 0,12258283 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,874E-03 0,12169455 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,874E-03 0,12081905 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,874E-03 0,11995605 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,874E-03 0,1191053 ! response to protozoan GO:0001562 13 5 0,000 6,874E-03 0,11826653 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,874E-03 0,11743949 ! lymph vessel development GO:0001945 10 5 0,000 6,874E-03 0,11662394 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,874E-03 0,11581964 ! endochondral ossification GO:0001958 17 5 0,000 6,874E-03 0,11502635 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,874E-03 0,11424386 ! single strand break repair GO:0000012 8 5 0,000 6,874E-03 0,11347194 ! parathyroid gland development GO:0060017 14 5 0,000 6,874E-03 0,11271039 ! anagen GO:0042640 7 5 0,000 6,874E-03 0,11195898 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,874E-03 0,11121753 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,874E-03 0,11048584 ! cytokine secretion GO:0050663 15 5 0,000 6,874E-03 0,10976371 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,874E-03 0,10905096 ! ceramide catabolic process GO:0046514 7 5 0,000 6,874E-03 0,1083474 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,874E-03 0,10765287 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,874E-03 0,10696718 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,874E-03 0,10629018 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,874E-03 0,10562168 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,874E-03 0,10496155 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,874E-03 0,10430961 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,874E-03 0,10366573 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,874E-03 0,10302974 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,874E-03 0,10240151 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,874E-03 0,10178089 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,874E-03 0,10116776 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,874E-03 0,10056196 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,874E-03 0,09996338 ! microvillus organization GO:0032528 8 5 0,000 6,874E-03 0,09937188 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 6,874E-03 0,09878734 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,874E-03 0,09820964 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,874E-03 0,09763865 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,874E-03 0,09707426 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,874E-03 0,09651637 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,874E-03 0,09596484 ! polyol biosynthetic process GO:0046173 6 5 0,000 6,874E-03 0,09541959 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,874E-03 0,0948805 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,874E-03 0,09434746 ! muscle cell migration GO:0014812 8 5 0,000 6,874E-03 0,09382038 ! mitochondrial fission GO:0000266 8 5 0,000 6,874E-03 0,09329915 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,874E-03 0,09278369 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,874E-03 0,09227389 ! mRNA transcription GO:0009299 10 5 0,000 6,874E-03 0,09176966 ! nerve growth factor processing GO:0032455 9 5 0,000 6,874E-03 0,09127091 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,874E-03 0,09077755 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,874E-03 0,0902895 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,874E-03 0,08980667 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,874E-03 0,08932898 ! monocyte activation GO:0042117 10 5 0,000 6,874E-03 0,08885634 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,874E-03 0,08838867 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,874E-03 0,0879259 ! response to food GO:0032094 6 5 0,000 6,874E-03 0,08746796 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,874E-03 0,08701475 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,874E-03 0,08656623 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,874E-03 0,0861223 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,874E-03 0,0856829 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,874E-03 0,08524796 ! forebrain neuron development GO:0021884 13 5 0,000 6,874E-03 0,08481741 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,874E-03 0,08439119 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,874E-03 0,08396924 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,874E-03 0,08355148 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,874E-03 0,08313786 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,874E-03 0,08272831 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,874E-03 0,08232278 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,874E-03 0,08192121 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,874E-03 0,08152353 ! lipid glycosylation GO:0030259 7 5 0,000 6,874E-03 0,0811297 ! nucleobase transport GO:0015851 6 5 0,000 6,874E-03 0,08073965 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,874E-03 0,08035334 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,874E-03 0,0799707 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,874E-03 0,0795917 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,874E-03 0,07921626 ! basic amino acid transport GO:0015802 12 5 0,000 6,874E-03 0,07884436 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,874E-03 0,07847592 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,874E-03 0,07811092 ! actin nucleation GO:0045010 11 5 0,000 6,874E-03 0,07774929 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,874E-03 0,077391 ! depurination GO:0045007 5 5 0,000 6,874E-03 0,077036 ! depyrimidination GO:0045008 10 5 0,000 6,874E-03 0,07668424 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,874E-03 0,07633567 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,874E-03 0,07599026 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,874E-03 0,07564796 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,874E-03 0,07530873 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,874E-03 0,07497253 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,874E-03 0,07463932 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,874E-03 0,07430906 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,874E-03 0,07398171 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,874E-03 0,07365723 ! activated T cell proliferation GO:0050798 16 5 0,000 6,874E-03 0,07333558 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,874E-03 0,07301673 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,874E-03 0,07270064 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,874E-03 0,07238727 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,874E-03 0,0720766 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,874E-03 0,07176858 ! response to arsenic GO:0046685 11 5 0,000 6,874E-03 0,07146318 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,874E-03 0,07116037 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,874E-03 0,07086012 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,874E-03 0,07056239 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,874E-03 0,07026714 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,874E-03 0,06997437 ! response to mercury ion GO:0046689 8 5 0,000 6,874E-03 0,06968402 ! response to cadmium ion GO:0046686 7 5 0,000 6,874E-03 0,06939606 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,874E-03 0,06911048 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,874E-03 0,06882724 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,874E-03 0,06854632 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,874E-03 0,06826767 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,874E-03 0,06799129 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,874E-03 0,06771713 ! decidualization GO:0046697 11 5 0,000 6,874E-03 0,06744517 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,874E-03 0,06717539 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,874E-03 0,06690776 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,874E-03 0,06664225 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 6,874E-03 0,06637884 ! embryonic cleavage GO:0040016 6 5 0,000 6,874E-03 0,06611751 ! peroxisome fission GO:0016559 5 5 0,000 6,874E-03 0,06585823 ! histone demethylation GO:0016577 13 5 0,000 6,874E-03 0,06560097 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,874E-03 0,06534571 ! mitotic recombination GO:0006312 9 5 0,000 6,874E-03 0,06509243 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,874E-03 0,06484111 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,874E-03 0,06459172 ! metaphase plate congression GO:0051310 7 5 0,000 6,874E-03 0,06434424 ! regulation of sterol transport GO:0032371 7 5 0,000 6,874E-03 0,06409866 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,874E-03 0,06385493 ! enteric nervous system development GO:0048484 8 5 0,000 6,874E-03 0,06361306 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,874E-03 0,06337301 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,874E-03 0,06313477 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,874E-03 0,06289831 ! muscle cell proliferation GO:0033002 12 5 0,000 6,874E-03 0,06266361 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,874E-03 0,06243066 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,874E-03 0,06219944 ! B cell homeostasis GO:0001782 13 5 0,000 6,874E-03 0,06196992 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,874E-03 0,06174209 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,874E-03 0,06151593 ! metaphase GO:0051323 11 5 0,000 6,874E-03 0,06129141 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,874E-03 0,06106854 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,874E-03 0,06084727 ! cellular response to nutrient GO:0031670 8 5 0,000 6,874E-03 0,06062761 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,874E-03 0,06040952 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,874E-03 0,060193 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,874E-03 0,05997803 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,874E-03 0,05976458 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,874E-03 0,05955265 ! response to redox state GO:0051775 6 5 0,000 6,874E-03 0,05934222 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,874E-03 0,05913327 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,874E-03 0,05892578 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,874E-03 0,05871975 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,874E-03 0,05851515 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,874E-03 0,05831197 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,874E-03 0,0581102 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,874E-03 0,05790982 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,874E-03 0,05771082 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,874E-03 0,05751318 ! striatum development GO:0021756 14 5 0,000 6,874E-03 0,05731689 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,874E-03 0,05712193 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,874E-03 0,0569283 ! glial cell migration GO:0008347 10 5 0,000 6,874E-03 0,05673597 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,874E-03 0,05654494 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,874E-03 0,05635519 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,874E-03 0,05616671 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,874E-03 0,05597949 ! T cell activation during immune response GO:0002286 9 5 0,000 6,874E-03 0,05579351 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,874E-03 0,05560877 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,874E-03 0,05542524 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,874E-03 0,05524292 ! neuroprotection GO:0043526 8 5 0,000 6,874E-03 0,0550618 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,874E-03 0,05488186 ! regulation of sensory perception GO:0051931 8 5 0,000 6,874E-03 0,05470309 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,874E-03 0,05452548 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,874E-03 0,05434902 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,874E-03 0,0541737 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,874E-03 0,05399951 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,874E-03 0,05382643 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,874E-03 0,05365447 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,874E-03 0,05348359 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,874E-03 0,0533138 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,874E-03 0,05314509 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,874E-03 0,05297744 ! spindle assembly GO:0051225 6 5 0,000 6,874E-03 0,05281084 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,874E-03 0,05264529 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,874E-03 0,05248077 ! protein palmitoylation GO:0018345 12 5 0,000 6,874E-03 0,05231728 ! drug metabolic process GO:0017144 7 5 0,000 6,874E-03 0,05215481 ! stem cell division GO:0017145 11 5 0,000 6,874E-03 0,05199334 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,874E-03 0,05183286 ! organ regeneration GO:0031100 7 5 0,000 6,874E-03 0,05167338 ! carnitine metabolic process GO:0009437 8 5 0,000 6,874E-03 0,05151487 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,874E-03 0,05135733 ! response to inorganic substance GO:0010035 173 90 1,000 6,902E-03 0,05140365 ! positive regulation of protein modification process GO:0031401 156 90 1,000 6,902E-03 0,05124741 ! regulation of cell adhesion GO:0030155 241 92 1,000 7,201E-03 0,05330778 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 7,353E-03 0,0542673 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 8,133E-03 0,05984889 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,244E-03 0,06047754 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,244E-03 0,06029647 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 8,244E-03 0,06011648 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 8,244E-03 0,05993756 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,244E-03 0,05975971 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 8,244E-03 0,0595829 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 8,244E-03 0,05940714 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,244E-03 0,05923241 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 8,244E-03 0,05905871 ! response to oxygen radical GO:0000305 11 6 0,000 8,244E-03 0,05888603 ! positive regulation of axon extension GO:0045773 13 6 0,000 8,244E-03 0,05871435 ! myoblast cell fate commitment GO:0048625 18 6 0,000 8,244E-03 0,05854366 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 8,244E-03 0,05837397 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 8,244E-03 0,05820526 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,244E-03 0,05803752 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,244E-03 0,05787075 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 8,244E-03 0,05770493 ! forebrain regionalization GO:0021871 9 6 0,000 8,244E-03 0,05754006 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,244E-03 0,05737613 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,244E-03 0,05721313 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 8,244E-03 0,05705105 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,244E-03 0,05688989 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 8,244E-03 0,05672964 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 8,244E-03 0,05657028 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,244E-03 0,05641182 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 8,244E-03 0,05625425 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 8,244E-03 0,05609755 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,244E-03 0,05594172 ! malate metabolic process GO:0006108 13 6 0,000 8,244E-03 0,05578676 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 8,244E-03 0,05563265 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 8,244E-03 0,0554794 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 8,244E-03 0,05532698 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 8,244E-03 0,0551754 ! protein refolding GO:0042026 15 6 0,000 8,244E-03 0,05502465 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,244E-03 0,05487472 ! opsonization GO:0008228 8 6 0,000 8,244E-03 0,0547256 ! mating behavior GO:0007617 7 6 0,000 8,244E-03 0,05457729 ! erythrocyte maturation GO:0043249 8 6 0,000 8,244E-03 0,05442979 ! embryonic hemopoiesis GO:0035162 16 6 0,000 8,244E-03 0,05428307 ! protein amino acid dealkylation GO:0008214 15 6 0,000 8,244E-03 0,05413715 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 8,244E-03 0,05399201 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 8,244E-03 0,05384765 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,244E-03 0,05370405 ! response to interferon-gamma GO:0034341 16 6 0,000 8,244E-03 0,05356123 ! toxin metabolic process GO:0009404 11 6 0,000 8,244E-03 0,05341915 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,244E-03 0,05327783 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 8,244E-03 0,05313726 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 8,244E-03 0,05299742 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 8,244E-03 0,05285832 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 8,244E-03 0,05271995 ! cGMP-mediated signaling GO:0019934 14 6 0,000 8,244E-03 0,0525823 ! dorsal spinal cord development GO:0021516 10 6 0,000 8,244E-03 0,05244537 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,244E-03 0,05230914 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 8,244E-03 0,05217363 ! thymic T cell selection GO:0045061 16 6 0,000 8,244E-03 0,05203881 ! sphingoid catabolic process GO:0046521 8 6 0,000 8,244E-03 0,05190469 ! protein lipoylation GO:0009249 10 6 0,000 8,244E-03 0,05177126 ! transepithelial chloride transport GO:0030321 12 6 0,000 8,244E-03 0,05163851 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 8,244E-03 0,05150645 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,244E-03 0,05137505 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 8,244E-03 0,05124433 ! glutamate catabolic process GO:0006538 12 6 0,000 8,244E-03 0,05111427 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 8,244E-03 0,05098486 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,244E-03 0,05085611 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 8,244E-03 0,05072801 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,244E-03 0,05060055 ! hyperosmotic response GO:0006972 10 6 0,000 8,244E-03 0,05047374 ! L-serine biosynthetic process GO:0006564 7 6 0,000 8,244E-03 0,05034755 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 8,244E-03 0,050222 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 8,244E-03 0,05009707 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,244E-03 0,04997276 ! urea metabolic process GO:0019627 7 6 0,000 8,244E-03 0,04984906 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,244E-03 0,04972598 ! neutrophil activation GO:0042119 7 6 0,000 8,244E-03 0,0496035 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,244E-03 0,04948162 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 8,244E-03 0,04936034 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,244E-03 0,04923966 ! paraxial mesoderm development GO:0048339 16 6 0,000 8,244E-03 0,04911956 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 8,244E-03 0,04900005 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,244E-03 0,04888112 ! neuron apoptosis GO:0051402 15 6 0,000 8,244E-03 0,04876276 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,244E-03 0,04864498 ! T cell mediated immunity GO:0002456 17 6 0,000 8,244E-03 0,04852776 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,244E-03 0,04841111 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 8,244E-03 0,04829501 ! carnitine transport GO:0015879 10 6 0,000 8,244E-03 0,04817948 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,244E-03 0,04806449 ! positive regulation of exocytosis GO:0045921 11 6 0,000 8,244E-03 0,04795005 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 8,244E-03 0,04783615 ! early endosome to late endosome transport GO:0045022 16 6 0,000 8,244E-03 0,0477228 ! 5S class rRNA transcription GO:0042791 13 6 0,000 8,244E-03 0,04760998 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,244E-03 0,04749769 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 8,244E-03 0,04738593 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 8,244E-03 0,0472747 ! sodium ion homeostasis GO:0055078 12 6 0,000 8,244E-03 0,04716398 ! establishment of spindle localization GO:0051293 16 6 0,000 8,244E-03 0,04705379 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 8,244E-03 0,0469441 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,244E-03 0,04683493 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 8,244E-03 0,04672627 ! response to UV-C GO:0010225 14 6 0,000 8,244E-03 0,0466181 ! astrocyte development GO:0014002 16 6 0,000 8,244E-03 0,04651044 ! protein targeting to lysosome GO:0006622 12 6 0,000 8,244E-03 0,04640327 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,244E-03 0,0462966 ! interaction with symbiont GO:0051702 14 6 0,000 8,244E-03 0,04619041 ! regulation of dendrite development GO:0050773 16 6 0,000 8,244E-03 0,04608472 ! peptidyl-arginine modification GO:0018195 13 6 0,000 8,244E-03 0,0459795 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 8,244E-03 0,04587476 ! response to copper ion GO:0046688 10 6 0,000 8,244E-03 0,0457705 ! response to exogenous dsRNA GO:0043330 13 6 0,000 8,244E-03 0,04566671 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 8,244E-03 0,0455634 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,244E-03 0,04546054 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 8,244E-03 0,04535815 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,244E-03 0,04525623 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 8,244E-03 0,04515475 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,244E-03 0,04505374 ! nucleoside catabolic process GO:0009164 10 6 0,000 8,244E-03 0,04495317 ! hair follicle maturation GO:0048820 8 6 0,000 8,244E-03 0,04485305 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,244E-03 0,04475338 ! Schwann cell development GO:0014044 15 6 0,000 8,244E-03 0,04465415 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 8,244E-03 0,04455536 ! response to pheromone GO:0019236 6 6 0,000 8,244E-03 0,044457 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 8,244E-03 0,04435908 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 8,244E-03 0,04426158 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 8,244E-03 0,04416452 ! base conversion or substitution editing GO:0016553 6 6 0,000 8,244E-03 0,04406788 ! subpallium development GO:0021544 15 6 0,000 8,244E-03 0,04397166 ! neural tube patterning GO:0021532 8 6 0,000 8,244E-03 0,04387586 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 8,244E-03 0,04378048 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 8,244E-03 0,04368551 ! maintenance of organ identity GO:0048496 9 6 0,000 8,244E-03 0,04359095 ! G2 phase GO:0051319 16 6 0,000 8,244E-03 0,0434968 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 8,244E-03 0,04340306 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 8,244E-03 0,04330972 ! oxygen homeostasis GO:0032364 10 6 0,000 8,244E-03 0,04321678 ! establishment of planar polarity GO:0001736 7 6 0,000 8,244E-03 0,04312424 ! regulation of mast cell activation GO:0033003 13 6 0,000 8,244E-03 0,0430321 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,244E-03 0,04294034 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 8,244E-03 0,04284898 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,244E-03 0,04275801 ! receptor internalization GO:0031623 11 6 0,000 8,244E-03 0,04266742 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,244E-03 0,04257721 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 8,244E-03 0,04248739 ! neutrophil homeostasis GO:0001780 11 6 0,000 8,244E-03 0,04239794 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,244E-03 0,04230887 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 8,244E-03 0,04222017 ! protein deubiquitination GO:0016579 16 6 0,000 8,244E-03 0,04213184 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 8,244E-03 0,04204388 ! protein destabilization GO:0031648 9 6 0,000 8,244E-03 0,04195629 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 8,244E-03 0,04186907 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,244E-03 0,0417822 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 8,244E-03 0,04169569 ! regulation of viral transcription GO:0046782 11 6 0,000 8,244E-03 0,04160955 ! progesterone metabolic process GO:0042448 12 6 0,000 8,244E-03 0,04152375 ! negative regulation of axon extension GO:0030517 24 6 0,000 8,244E-03 0,04143831 ! removal of superoxide radicals GO:0019430 12 6 0,000 8,244E-03 0,04135323 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,244E-03 0,04126848 ! determination of adult lifespan GO:0008340 17 6 0,000 8,244E-03 0,04118409 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 8,244E-03 0,04110004 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 8,244E-03 0,04101634 ! neural plate development GO:0001840 9 6 0,000 8,244E-03 0,04093297 ! catecholamine transport GO:0051937 9 6 0,000 8,244E-03 0,04084994 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 8,244E-03 0,04076725 ! sensory cilium assembly GO:0035058 10 6 0,000 8,244E-03 0,04068489 ! organ or tissue specific immune response GO:0002251 8 6 0,000 8,244E-03 0,04060286 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 8,244E-03 0,04052117 ! maternal placenta development GO:0001893 12 6 0,000 8,244E-03 0,0404398 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 8,244E-03 0,04035876 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,244E-03 0,04027804 ! negative regulation of B cell activation GO:0050869 14 6 0,000 8,244E-03 0,04019765 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 8,244E-03 0,04011757 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 8,244E-03 0,04003781 ! positive regulation of coagulation GO:0050820 13 6 0,000 8,244E-03 0,03995837 ! cellular anion homeostasis GO:0030002 11 6 0,000 8,244E-03 0,03987925 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 9,611E-03 0,04640252 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,611E-03 0,046311 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,611E-03 0,04621983 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,611E-03 0,04612903 ! regulation of helicase activity GO:0051095 16 7 0,000 9,611E-03 0,04603858 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,611E-03 0,04594848 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,611E-03 0,04585874 ! sleep GO:0030431 16 7 0,000 9,611E-03 0,04576935 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,611E-03 0,0456803 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,611E-03 0,0455916 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,611E-03 0,04550325 ! prostate gland development GO:0030850 14 7 0,000 9,611E-03 0,04541523 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,611E-03 0,04532756 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,611E-03 0,04524022 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,611E-03 0,04515322 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,611E-03 0,04506656 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,611E-03 0,04498022 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,611E-03 0,04489422 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,611E-03 0,04480854 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,611E-03 0,04472319 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,611E-03 0,04463817 ! glycolipid transport GO:0046836 11 7 0,000 9,611E-03 0,04455346 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,611E-03 0,04446908 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,611E-03 0,04438502 ! neuron adhesion GO:0007158 14 7 0,000 9,611E-03 0,04430127 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 9,611E-03 0,04421784 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,611E-03 0,04413473 ! establishment of tissue polarity GO:0007164 8 7 0,000 9,611E-03 0,04405192 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,611E-03 0,04396943 ! mRNA stabilization GO:0048255 18 7 0,000 9,611E-03 0,04388724 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,611E-03 0,04380536 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,611E-03 0,04372379 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,611E-03 0,04364252 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,611E-03 0,04356155 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,611E-03 0,04348088 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,611E-03 0,04340051 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,611E-03 0,04332043 ! lipoprotein transport GO:0042953 14 7 0,000 9,611E-03 0,04324065 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,611E-03 0,04316117 ! rhythmic behavior GO:0007622 17 7 0,000 9,611E-03 0,04308197 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,611E-03 0,04300307 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,611E-03 0,04292445 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,611E-03 0,04284612 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,611E-03 0,04276808 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,611E-03 0,04269032 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,611E-03 0,04261284 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,611E-03 0,04253564 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,611E-03 0,04245873 ! mechanosensory behavior GO:0007638 16 7 0,000 9,611E-03 0,04238209 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,611E-03 0,04230572 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,611E-03 0,04222963 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,611E-03 0,04215382 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,611E-03 0,04207827 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,611E-03 0,042003 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,611E-03 0,04192799 ! spinal cord patterning GO:0021511 14 7 0,000 9,611E-03 0,04185325 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,611E-03 0,04177878 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,611E-03 0,04170457 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,611E-03 0,04163063 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,611E-03 0,04155695 ! adrenal gland development GO:0030325 17 7 0,000 9,611E-03 0,04148353 ! cysteine metabolic process GO:0006534 13 7 0,000 9,611E-03 0,04141036 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,611E-03 0,04133746 ! ovulation GO:0030728 10 7 0,000 9,611E-03 0,04126481 ! adenohypophysis development GO:0021984 11 7 0,000 9,611E-03 0,04119241 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,611E-03 0,04112027 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,611E-03 0,04104838 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,611E-03 0,04097675 ! microtubule nucleation GO:0007020 21 7 0,000 9,611E-03 0,04090536 ! proline biosynthetic process GO:0006561 10 7 0,000 9,611E-03 0,04083422 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,611E-03 0,04076333 ! thyroid hormone generation GO:0006590 13 7 0,000 9,611E-03 0,04069268 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 9,611E-03 0,04062228 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,611E-03 0,04055212 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,611E-03 0,0404822 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,611E-03 0,04041252 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,611E-03 0,04034308 ! galactose metabolic process GO:0006012 13 7 0,000 9,611E-03 0,04027389 ! vesicle fusion GO:0006906 20 7 0,000 9,611E-03 0,04020492 ! response to dietary excess GO:0002021 8 7 0,000 9,611E-03 0,0401362 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,611E-03 0,04006771 ! intracellular pH reduction GO:0051452 13 7 0,000 9,611E-03 0,03999945 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,611E-03 0,03993142 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,611E-03 0,03986363 ! organ growth GO:0035265 15 7 0,000 9,611E-03 0,03979606 ! nucleoside transport GO:0015858 11 7 0,000 9,611E-03 0,03972872 ! nucleoside salvage GO:0043174 11 7 0,000 9,611E-03 0,03966161 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,611E-03 0,03959473 ! male sex determination GO:0030238 15 7 0,000 9,611E-03 0,03952807 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,611E-03 0,03946164 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,611E-03 0,03939543 ! parturition GO:0007567 16 7 0,000 9,611E-03 0,03932944 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,611E-03 0,03926367 ! rRNA modification GO:0000154 14 7 0,000 9,611E-03 0,03919812 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,611E-03 0,03913279 ! spindle checkpoint GO:0031577 16 7 0,000 9,611E-03 0,03906768 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,611E-03 0,03900278 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,611E-03 0,0389381 ! monocyte differentiation GO:0030224 16 7 0,000 9,611E-03 0,03887363 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,611E-03 0,03880938 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,611E-03 0,03874534 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,611E-03 0,03868151 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,611E-03 0,03861789 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,611E-03 0,03855448 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,611E-03 0,03849127 ! fibrinolysis GO:0042730 11 7 0,000 9,611E-03 0,03842827 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,611E-03 0,03836548 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,611E-03 0,0383029 ! eating behavior GO:0042755 8 7 0,000 9,611E-03 0,03824051 ! B cell lineage commitment GO:0002326 21 7 0,000 9,611E-03 0,03817833 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,611E-03 0,03811636 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,611E-03 0,03805458 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,611E-03 0,037993 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,611E-03 0,03793162 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,611E-03 0,03787044 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,611E-03 0,03780946 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,611E-03 0,03774867 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,611E-03 0,03768808 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,611E-03 0,03762768 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,611E-03 0,03756748 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,611E-03 0,03750747 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,611E-03 0,03744765 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,611E-03 0,03738802 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,611E-03 0,03732858 ! histone ubiquitination GO:0016574 9 7 0,000 9,611E-03 0,03726933 ! regulation of meiosis GO:0040020 12 7 0,000 9,611E-03 0,03721026 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,611E-03 0,03715139 ! T cell lineage commitment GO:0002360 16 7 0,000 9,611E-03 0,03709269 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,611E-03 0,03703419 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,611E-03 0,03697587 ! membrane to membrane docking GO:0022614 14 7 0,000 9,611E-03 0,03691773 ! transcription termination GO:0006353 14 7 0,000 9,611E-03 0,03685977 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,611E-03 0,036802 ! anaphase GO:0051322 18 7 0,000 9,611E-03 0,03674441 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,611E-03 0,03668699 ! axonal fasciculation GO:0007413 19 7 0,000 9,611E-03 0,03662976 ! negative regulation of nuclear division GO:0051784 15 7 0,000 9,611E-03 0,0365727 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 9,611E-03 0,03651582 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,611E-03 0,03645912 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,611E-03 0,0364026 ! diuresis GO:0030146 12 7 0,000 9,611E-03 0,03634625 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,611E-03 0,03629007 ! thiamin metabolic process GO:0006772 7 7 0,000 9,611E-03 0,03623407 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,611E-03 0,03617824 ! antibiotic transport GO:0042891 9 7 0,000 9,611E-03 0,03612258 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,611E-03 0,03606709 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,611E-03 0,03601177 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,611E-03 0,03595662 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,611E-03 0,03590164 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,611E-03 0,03584683 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,611E-03 0,03579219 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,611E-03 0,03573771 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,611E-03 0,0356834 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,611E-03 0,03562925 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 9,611E-03 0,03557527 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,611E-03 0,03552145 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,611E-03 0,03546779 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,611E-03 0,03541429 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,611E-03 0,03536096 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 9,611E-03 0,03530778 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,611E-03 0,03525477 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,611E-03 0,03520191 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,611E-03 0,03514921 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,611E-03 0,03509667 ! muscle adaptation GO:0043500 13 7 0,000 9,611E-03 0,03504429 ! embryonic heart tube development GO:0035050 14 7 0,000 9,611E-03 0,03499206 ! retina homeostasis GO:0001895 12 7 0,000 9,611E-03 0,03493999 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,611E-03 0,03488808 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,611E-03 0,03483631 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 9,611E-03 0,0347847 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,611E-03 0,03473325 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01097659 0,03960978 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01097659 0,03955135 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01097659 0,0394931 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01097659 0,03943503 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01097659 0,03937712 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01097659 0,03931938 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01097659 0,03926181 ! male meiosis GO:0007140 9 8 0,000 0,01097659 0,03920441 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01097659 0,03914718 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01097659 0,03909011 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01097659 0,03903321 ! meiotic prophase I GO:0007128 14 8 0,000 0,01097659 0,03897648 ! response to zinc ion GO:0010043 12 8 0,000 0,01097659 0,03891991 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01097659 0,0388635 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01097659 0,03880726 ! oligopeptide transport GO:0006857 16 8 0,000 0,01097659 0,03875118 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01097659 0,03869526 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01097659 0,03863951 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01097659 0,03858391 ! signal peptide processing GO:0006465 12 8 0,000 0,01097659 0,03852847 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01097659 0,0384732 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01097659 0,03841808 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01097659 0,03836312 ! succinate metabolic process GO:0006105 17 8 0,000 0,01097659 0,03830831 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01097659 0,03825366 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01097659 0,03819917 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01097659 0,03814483 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01097659 0,03809065 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01097659 0,03803662 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01097659 0,03798274 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01097659 0,03792902 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01097659 0,03787545 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01097659 0,03782203 ! reflex GO:0060004 17 8 0,000 0,01097659 0,03776876 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01097659 0,03771564 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01097659 0,03766267 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01097659 0,03760984 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01097659 0,03755717 ! pigment granule organization GO:0048753 17 8 0,000 0,01097659 0,03750464 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01097659 0,03745226 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01097659 0,03740002 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01097659 0,03734794 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01097659 0,03729599 ! histidine catabolic process GO:0006548 10 8 0,000 0,01097659 0,03724419 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01097659 0,03719254 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01097659 0,03714102 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01097659 0,03708965 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01097659 0,03703842 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01097659 0,03698733 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01097659 0,03693639 ! melanin metabolic process GO:0006582 17 8 0,000 0,01097659 0,03688558 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01097659 0,03683491 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01097659 0,03678439 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01097659 0,036734 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01097659 0,03668375 ! macrophage activation GO:0042116 13 8 0,000 0,01097659 0,03663363 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01097659 0,03658365 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01097659 0,03653381 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01097659 0,03648411 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01097659 0,03643454 ! purine salvage GO:0043101 12 8 0,000 0,01097659 0,0363851 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01097659 0,0363358 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01097659 0,03628663 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01097659 0,03623759 ! osteoblast development GO:0002076 17 8 0,000 0,01097659 0,03618869 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01097659 0,03613992 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01097659 0,03609128 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01097659 0,03604277 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01097659 0,03599439 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01097659 0,03594614 ! response to UV-B GO:0010224 17 8 0,000 0,01097659 0,03589802 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01097659 0,03585002 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01097659 0,03580216 ! intermediate filament organization GO:0045109 12 8 0,000 0,01097659 0,03575442 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01097659 0,03570681 ! cellular extravasation GO:0045123 13 8 0,000 0,01097659 0,03565933 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01097659 0,03561198 ! response to antibiotic GO:0046677 11 8 0,000 0,01097659 0,03556475 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01097659 0,03551764 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01097659 0,03547066 ! DNA topological change GO:0006265 12 8 0,000 0,01097659 0,0354238 ! response to tropane GO:0014073 15 8 0,000 0,01097659 0,03537707 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01097659 0,03533046 ! melanosome transport GO:0032402 13 8 0,000 0,01097659 0,03528397 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01097659 0,03523761 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01097659 0,03519136 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01097659 0,03514524 ! mast cell activation GO:0045576 14 8 0,000 0,01097659 0,03509924 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01097659 0,03505336 ! gas homeostasis GO:0033483 14 8 0,000 0,01097659 0,0350076 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01097659 0,03496195 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01097659 0,03491643 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01097659 0,03487102 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01097659 0,03482574 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01097659 0,03478057 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01097659 0,03473552 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01097659 0,03469058 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01097659 0,03464576 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01097659 0,03460106 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01097659 0,03455647 ! response to tumor cell GO:0002347 16 8 0,000 0,01097659 0,03451199 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01097659 0,03446763 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01097659 0,03442339 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01097659 0,03437925 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01097659 0,03433523 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01097659 0,03429133 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01097659 0,03424753 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01097659 0,03420385 ! hormone catabolic process GO:0042447 17 8 0,000 0,01097659 0,03416028 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01097659 0,03411682 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01097659 0,03407347 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01097659 0,03403023 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01097659 0,03398709 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01097659 0,03394407 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01097659 0,03390116 ! adult feeding behavior GO:0008343 10 8 0,000 0,01097659 0,03385836 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01097659 0,03381566 ! ATP catabolic process GO:0006200 11 8 0,000 0,01097659 0,03377307 ! blastocyst growth GO:0001832 19 8 0,000 0,01097659 0,03373059 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01097659 0,03368821 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01097659 0,03364594 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01097659 0,03360378 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01097659 0,03356172 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01097659 0,03351977 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01097659 0,03347792 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01097659 0,03343618 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01097659 0,03339454 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01097659 0,03335301 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01097659 0,03331157 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01097659 0,03327025 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01097659 0,03322902 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01097659 0,03318789 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01097659 0,03314687 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01097659 0,03310595 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01097659 0,03306513 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01097659 0,03302441 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01097659 0,03298379 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01097659 0,03294327 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01097659 0,03290284 ! axon extension GO:0048675 16 9 0,000 0,01234034 0,03694541 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01234034 0,03690019 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01234034 0,03685508 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01234034 0,03681008 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01234034 0,03676519 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01234034 0,03672041 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01234034 0,03667573 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01234034 0,03663117 ! reproductive behavior GO:0019098 22 9 0,000 0,01234034 0,03658672 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01234034 0,03654237 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01234034 0,03649813 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01234034 0,036454 ! UTP metabolic process GO:0046051 10 9 0,000 0,01234034 0,03640997 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01234034 0,03636605 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01234034 0,03632223 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01234034 0,03627852 ! artery development GO:0060840 25 9 0,000 0,01234034 0,03623492 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01234034 0,03619142 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01234034 0,03614803 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01234034 0,03610474 ! equilibrioception GO:0050957 20 9 0,000 0,01234034 0,03606155 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01234034 0,03601846 ! chemosensory behavior GO:0007635 21 9 0,000 0,01234034 0,03597548 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01234034 0,0359326 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01234034 0,03588983 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01234034 0,03584715 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01234034 0,03580458 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01234034 0,0357621 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01234034 0,03571973 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01234034 0,03567746 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01234034 0,03563529 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01234034 0,03559322 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01234034 0,03555124 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01234034 0,03550937 ! protein targeting to ER GO:0045047 25 9 0,000 0,01234034 0,03546759 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01234034 0,03542592 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01234034 0,03538434 ! T cell selection GO:0045058 27 9 0,000 0,01234034 0,03534285 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01234034 0,03530147 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01234034 0,03526018 ! glycine catabolic process GO:0006546 15 9 0,000 0,01234034 0,03521899 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01234034 0,03517789 ! endosome organization GO:0007032 20 9 0,000 0,01234034 0,03513689 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01234034 0,03509599 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01234034 0,03505518 ! mannose metabolic process GO:0006013 13 9 0,000 0,01234034 0,03501446 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01234034 0,03497384 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01234034 0,03493332 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01234034 0,03489289 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01234034 0,03485255 ! receptor clustering GO:0043113 20 9 0,000 0,01234034 0,0348123 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01234034 0,03477215 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01234034 0,03473209 ! retinol metabolic process GO:0042572 20 9 0,000 0,01234034 0,03469212 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01234034 0,03465225 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01234034 0,03461246 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01234034 0,03457277 ! macrophage differentiation GO:0030225 15 9 0,000 0,01234034 0,03453317 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01234034 0,03449365 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01234034 0,03445423 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01234034 0,0344149 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01234034 0,03437566 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01234034 0,03433651 ! response to amine stimulus GO:0014075 13 9 0,000 0,01234034 0,03429744 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01234034 0,03425847 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01234034 0,03421958 ! erythrocyte development GO:0048821 17 9 0,000 0,01234034 0,03418079 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01234034 0,03414208 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01234034 0,03410345 ! renal water homeostasis GO:0003091 15 9 0,000 0,01234034 0,03406492 ! postreplication repair GO:0006301 25 9 0,000 0,01234034 0,03402647 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01234034 0,03398811 ! icosanoid secretion GO:0032309 15 9 0,000 0,01234034 0,03394984 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01234034 0,03391165 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01234034 0,03387354 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01234034 0,03383553 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01234034 0,03379759 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01234034 0,03375975 ! sterol catabolic process GO:0016127 14 9 0,000 0,01234034 0,03372198 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01234034 0,03368431 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01234034 0,03364671 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01234034 0,0336092 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01234034 0,03357178 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01234034 0,03353443 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01234034 0,03349717 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01234034 0,03345999 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01234034 0,0334229 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01234034 0,03338588 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01234034 0,03334895 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01234034 0,0333121 ! purine base metabolic process GO:0006144 25 9 0,000 0,01234034 0,03327534 ! pigment granule transport GO:0051904 17 9 0,000 0,01234034 0,03323865 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01234034 0,03320204 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01234034 0,03316552 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01234034 0,03312907 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01234034 0,0330927 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01234034 0,03305642 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01234034 0,03302021 ! mitochondrion localization GO:0051646 18 9 0,000 0,01234034 0,03298409 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01370225 0,03658425 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01370225 0,03654431 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01370225 0,03650446 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01370225 0,03646469 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01370225 0,03642502 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01370225 0,03638542 ! associative learning GO:0008306 21 10 0,000 0,01370225 0,03634592 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01370225 0,0363065 ! phosphate transport GO:0006817 24 10 0,000 0,01370225 0,03626716 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01370225 0,03622791 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01370225 0,03618875 ! CTP metabolic process GO:0046036 11 10 0,000 0,01370225 0,03614967 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01370225 0,03611067 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01370225 0,03607176 ! GTP metabolic process GO:0046039 11 10 0,000 0,01370225 0,03603293 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01370225 0,03599418 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01370225 0,03595552 ! social behavior GO:0035176 29 10 0,000 0,01370225 0,03591694 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01370225 0,03587845 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01370225 0,03584003 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01370225 0,0358017 ! androgen metabolic process GO:0008209 17 10 0,000 0,01370225 0,03576345 ! phospholipid efflux GO:0033700 19 10 0,000 0,01370225 0,03572528 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01370225 0,0356872 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01370225 0,03564919 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01370225 0,03561127 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01370225 0,03557342 ! lung alveolus development GO:0048286 26 10 0,000 0,01370225 0,03553566 ! pathogenesis GO:0009405 17 10 0,000 0,01370225 0,03549797 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01370225 0,03546037 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01370225 0,03542285 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01370225 0,0353854 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01370225 0,03534804 ! endoderm development GO:0007492 18 10 0,000 0,01370225 0,03531075 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01370225 0,03527354 ! arginine catabolic process GO:0006527 17 10 0,000 0,01370225 0,03523641 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01370225 0,03519936 ! proline metabolic process GO:0006560 13 10 0,000 0,01370225 0,03516238 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01370225 0,03512549 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01370225 0,03508867 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01370225 0,03505193 ! V(D)J recombination GO:0033151 34 10 0,000 0,01370225 0,03501526 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01370225 0,03497867 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01370225 0,03494216 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 0,01370225 0,03490572 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01370225 0,03486936 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01370225 0,03483308 ! multicellular organism growth GO:0035264 19 10 0,000 0,01370225 0,03479687 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01370225 0,03476074 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01370225 0,03472468 ! ruffle organization GO:0031529 17 10 0,000 0,01370225 0,03468869 ! epithelial cell development GO:0002064 21 10 0,000 0,01370225 0,03465278 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01370225 0,03461695 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01370225 0,03458119 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01370225 0,0345455 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01370225 0,03450989 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01370225 0,03447435 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01370225 0,03443888 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01370225 0,03440348 ! motor axon guidance GO:0008045 22 10 0,000 0,01370225 0,03436816 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01370225 0,03433291 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01370225 0,03429774 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01370225 0,03426263 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01370225 0,0342276 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01370225 0,03419264 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01370225 0,03415774 ! segment specification GO:0007379 15 10 0,000 0,01370225 0,03412293 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01370225 0,03408818 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01370225 0,0340535 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01370225 0,03401889 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01370225 0,03398436 ! response to dsRNA GO:0043331 23 10 0,000 0,01370225 0,03394989 ! DNA ligation GO:0006266 18 10 0,000 0,01370225 0,03391549 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01370225 0,03388116 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01370225 0,03384691 ! melanosome localization GO:0032400 16 10 0,000 0,01370225 0,03381272 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01370225 0,0337786 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01370225 0,03374455 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01370225 0,03371056 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01370225 0,03367665 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01370225 0,0336428 ! induction of an organ GO:0001759 17 10 0,000 0,01370225 0,03360903 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01370225 0,03357532 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01370225 0,03354167 ! protein sumoylation GO:0016925 17 10 0,000 0,01370225 0,0335081 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01370225 0,03347459 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01370225 0,03344115 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01370225 0,03340777 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01370225 0,03337447 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01370225 0,03334123 ! salivary gland development GO:0007431 28 10 0,000 0,01370225 0,03330805 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01370225 0,03327494 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01370225 0,0332419 ! midbrain development GO:0030901 14 10 0,000 0,01370225 0,03320892 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01370225 0,03317601 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01370225 0,03314316 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01370225 0,03311038 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01370225 0,03307766 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01370225 0,033045 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01370225 0,03301242 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01370225 0,03297989 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01370225 0,03294743 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01370225 0,03291503 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01370225 0,0328827 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01370225 0,03285043 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01370225 0,03281823 ! blastocyst formation GO:0001825 18 10 0,000 0,01370225 0,03278608 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01370225 0,032754 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01370225 0,03272198 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01370225 0,03269003 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01370225 0,03265814 ! response to nicotine GO:0035094 20 10 0,000 0,01370225 0,03262631 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01370225 0,03259454 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01370225 0,03256283 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01506231 0,03576019 ! respiratory burst GO:0045730 17 11 0,000 0,01506231 0,03572547 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01506231 0,03569082 ! neuron fate specification GO:0048665 18 11 0,000 0,01506231 0,03565623 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01506231 0,03562171 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01506231 0,03558726 ! thyroid gland development GO:0030878 26 11 0,000 0,01506231 0,03555288 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01506231 0,03551856 ! synapsis GO:0007129 14 11 0,000 0,01506231 0,03548431 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01506231 0,03545013 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01506231 0,03541601 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01506231 0,03538195 ! response to pain GO:0048265 27 11 0,000 0,01506231 0,03534796 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01506231 0,03531404 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01506231 0,03528018 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01506231 0,03524639 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01506231 0,03521266 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01506231 0,035179 ! bone resorption GO:0045453 16 11 0,000 0,01506231 0,0351454 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01506231 0,03511186 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01506231 0,03507839 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01506231 0,03504498 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01506231 0,03501164 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01506231 0,03497836 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01506231 0,03494514 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01506231 0,03491198 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01506231 0,03487889 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01506231 0,03484586 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01506231 0,0348129 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01506231 0,03477999 ! UV protection GO:0009650 20 11 0,000 0,01506231 0,03474715 ! adult heart development GO:0007512 16 11 0,000 0,01506231 0,03471437 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01506231 0,03468165 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01506231 0,03464899 ! macroautophagy GO:0016236 19 11 0,000 0,01506231 0,0346164 ! temperature homeostasis GO:0001659 18 11 0,000 0,01506231 0,03458386 ! behavioral fear response GO:0001662 27 11 0,000 0,01506231 0,03455139 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01506231 0,03451898 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01506231 0,03448663 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01506231 0,03445434 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01506231 0,03442211 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01506231 0,03438994 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01506231 0,03435783 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01506231 0,03432578 ! regulation of organ growth GO:0046620 14 11 0,000 0,01506231 0,03429379 ! pigment granule localization GO:0051875 20 11 0,000 0,01506231 0,03426185 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01506231 0,03422998 ! vasoconstriction GO:0042310 20 11 0,000 0,01506231 0,03419817 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01506231 0,03416642 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01506231 0,03413472 ! embryonic axis specification GO:0000578 19 11 0,000 0,01506231 0,03410309 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01506231 0,03407151 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01506231 0,03403999 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01506231 0,03400853 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01506231 0,03397713 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01506231 0,03394579 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01506231 0,0339145 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01506231 0,03388327 ! prophase GO:0051324 17 11 0,000 0,01506231 0,0338521 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01506231 0,03382098 ! nucleosome positioning GO:0016584 15 11 0,000 0,01506231 0,03378993 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01506231 0,03375893 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01506231 0,03372798 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01506231 0,0336971 ! apical protein localization GO:0045176 18 11 0,000 0,01506231 0,03366627 ! acid secretion GO:0046717 20 11 0,000 0,01506231 0,0336355 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01506231 0,03360478 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01506231 0,03357412 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01506231 0,03354351 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01506231 0,03351296 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01506231 0,03348247 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01506231 0,03345203 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01506231 0,03342165 ! cholesterol efflux GO:0033344 21 11 0,000 0,01506231 0,03339132 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01506231 0,03336104 ! oocyte development GO:0048599 20 11 0,000 0,01506231 0,03333083 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01506231 0,03330066 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01506231 0,03327055 ! embryonic gut development GO:0048566 19 11 0,000 0,01506231 0,0332405 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01506231 0,0332105 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01506231 0,03318055 ! activation of innate immune response GO:0002218 16 11 0,000 0,01506231 0,03315066 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01506231 0,03312082 ! lysogeny GO:0030069 22 11 0,000 0,01506231 0,03309104 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01506231 0,0330613 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01506231 0,03303163 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01506231 0,033002 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01506231 0,03297243 ! nucleus localization GO:0051647 22 11 0,000 0,01506231 0,03294291 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01642054 0,03588138 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01642054 0,03584932 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01642054 0,03581731 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01642054 0,03578536 ! virus-host interaction GO:0019048 30 12 0,000 0,01642054 0,03575346 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01642054 0,03572162 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01642054 0,03568984 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01642054 0,03565812 ! protein complex disassembly GO:0043241 28 12 0,000 0,01642054 0,03562645 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01642054 0,03559484 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01642054 0,03556328 ! hippocampus development GO:0021766 29 12 0,000 0,01642054 0,03553178 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01642054 0,03550034 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01642054 0,03546895 ! T cell proliferation GO:0042098 32 12 0,000 0,01642054 0,03543762 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01642054 0,03540634 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01642054 0,03537512 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01642054 0,03534395 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01642054 0,03531284 ! drug transport GO:0015893 16 12 0,000 0,01642054 0,03528178 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01642054 0,03525078 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01642054 0,03521983 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01642054 0,03518893 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01642054 0,03515809 ! focal adhesion formation GO:0048041 37 12 0,000 0,01642054 0,03512731 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01642054 0,03509657 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01642054 0,0350659 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01642054 0,03503527 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01642054 0,0350047 ! lipid digestion GO:0044241 21 12 0,000 0,01642054 0,03497418 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01642054 0,03494371 ! entry into host cell GO:0030260 34 12 0,000 0,01642054 0,0349133 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01642054 0,03488294 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01642054 0,03485264 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01642054 0,03482238 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01642054 0,03479218 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01642054 0,03476203 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01642054 0,03473193 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01642054 0,03470189 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01642054 0,0346719 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01642054 0,03464196 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01642054 0,03461207 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01642054 0,03458223 ! cranial nerve development GO:0021545 23 12 0,000 0,01642054 0,03455244 ! fucose catabolic process GO:0019317 25 12 0,000 0,01642054 0,03452271 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01642054 0,03449302 ! histone acetylation GO:0016573 27 12 0,000 0,01642054 0,03446339 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01642054 0,03443381 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01642054 0,03440428 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01642054 0,03437479 ! zymogen activation GO:0031638 18 12 0,000 0,01642054 0,03434536 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01642054 0,03431598 ! T cell homeostasis GO:0043029 28 12 0,000 0,01642054 0,03428665 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01642054 0,03425737 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01642054 0,03422814 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01642054 0,03419896 ! oocyte differentiation GO:0009994 21 12 0,000 0,01642054 0,03416983 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01642054 0,03414075 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01642054 0,03411172 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01642054 0,03408274 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01642054 0,03405381 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01642054 0,03402492 ! defense response to fungus GO:0050832 15 12 0,000 0,01642054 0,03399609 ! developmental induction GO:0031128 22 12 0,000 0,01642054 0,0339673 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01642054 0,03393857 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01642054 0,03390988 ! response to cold GO:0009409 17 12 0,000 0,01642054 0,03388124 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01642054 0,03385265 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01642054 0,0338241 ! localization within membrane GO:0051668 26 12 0,000 0,01642054 0,03379561 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01777694 0,03655644 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01777694 0,0365257 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01777694 0,036495 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01777694 0,03646436 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01777694 0,03643377 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01777694 0,03640323 ! peroxisomal transport GO:0043574 28 13 0,000 0,01777694 0,03637274 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01777694 0,03634231 ! cartilage condensation GO:0001502 22 13 0,000 0,01777694 0,03631192 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01777694 0,03628158 ! organelle fusion GO:0048284 36 13 0,000 0,01777694 0,0362513 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01777694 0,03622106 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01777694 0,03619088 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01777694 0,03616075 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01777694 0,03613066 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01777694 0,03610063 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01777694 0,03607064 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01777694 0,03604071 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01777694 0,03601083 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01777694 0,03598099 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01777694 0,0359512 ! methionine metabolic process GO:0006555 31 13 0,000 0,01777694 0,03592147 ! plasma membrane organization GO:0007009 27 13 0,000 0,01777694 0,03589178 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01777694 0,03586214 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01777694 0,03583255 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01777694 0,03580301 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01777694 0,03577352 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01777694 0,03574408 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01777694 0,03571468 ! exocrine system development GO:0035272 34 13 0,000 0,01777694 0,03568534 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01777694 0,03565604 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01777694 0,03562679 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01777694 0,03559759 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01777694 0,03556843 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01777694 0,03553933 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01777694 0,03551027 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01777694 0,03548125 ! protein homotetramerization GO:0051289 24 13 0,000 0,01777694 0,03545229 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01777694 0,03542337 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01777694 0,0353945 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01777694 0,03536568 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01777694 0,0353369 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01777694 0,03530818 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01777694 0,03527949 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01777694 0,03525086 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01777694 0,03522227 ! histone methylation GO:0016571 29 13 0,000 0,01777694 0,03519372 ! chromatin silencing GO:0006342 29 13 0,000 0,01777694 0,03516523 ! gland morphogenesis GO:0022612 31 13 0,000 0,01777694 0,03513678 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01777694 0,03510837 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01777694 0,03508001 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01777694 0,0350517 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01777694 0,03502343 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01777694 0,03499521 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01777694 0,03496703 ! spleen development GO:0048536 24 13 0,000 0,01777694 0,0349389 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01777694 0,03491082 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01777694 0,03488278 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01777694 0,03485478 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01777694 0,03482683 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01777694 0,03479892 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01777694 0,03477106 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01777694 0,03474324 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01777694 0,03471547 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01777694 0,03468774 ! insulin secretion GO:0030073 24 13 0,000 0,01777694 0,03466006 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01777694 0,03463242 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01777694 0,03460482 ! acrosome reaction GO:0007340 19 13 0,000 0,01777694 0,03457727 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01777694 0,03454977 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01777694 0,0345223 ! rRNA transcription GO:0009303 28 14 0,000 0,0191315 0,03712331 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0191315 0,03709385 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0191315 0,03706443 ! water transport GO:0006833 21 14 0,000 0,0191315 0,03703506 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0191315 0,03700574 ! non-recombinational repair GO:0000726 29 14 0,000 0,0191315 0,03697646 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0191315 0,03694723 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0191315 0,03691805 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0191315 0,03688891 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0191315 0,03685982 ! lipid localization GO:0010876 32 14 0,000 0,0191315 0,03683077 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0191315 0,03680177 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0191315 0,03677282 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0191315 0,03674391 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0191315 0,03671504 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0191315 0,03668622 ! arginine metabolic process GO:0006525 21 14 0,000 0,0191315 0,03665745 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0191315 0,03662872 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0191315 0,03660004 ! regulation of heart rate GO:0002027 25 14 0,000 0,0191315 0,0365714 ! fear response GO:0042596 34 14 0,000 0,0191315 0,03654281 ! organic alcohol transport GO:0015850 29 14 0,000 0,0191315 0,03651426 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0191315 0,03648575 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0191315 0,03645729 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0191315 0,03642888 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0191315 0,03640051 ! bone mineralization GO:0030282 18 14 0,000 0,0191315 0,03637218 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0191315 0,0363439 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0191315 0,03631566 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0191315 0,03628746 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0191315 0,03625931 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0191315 0,0362312 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0191315 0,03620314 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0191315 0,03617512 ! ribosome assembly GO:0042255 18 14 0,000 0,0191315 0,03614714 ! cerebellum development GO:0021549 23 14 0,000 0,0191315 0,0361192 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0191315 0,03609131 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0191315 0,03606346 ! response to gamma radiation GO:0010332 30 14 0,000 0,0191315 0,03603566 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0191315 0,0360079 ! NADP metabolic process GO:0006739 24 14 0,000 0,0191315 0,03598018 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0191315 0,0359525 ! oxygen transport GO:0015671 22 14 0,000 0,0191315 0,03592487 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0191315 0,03589727 ! male genitalia development GO:0030539 26 14 0,000 0,0191315 0,03586972 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0191315 0,03584222 ! regulation of axon extension GO:0030516 43 14 0,000 0,0191315 0,03581475 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,0191315 0,03578733 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0191315 0,03575995 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0191315 0,03573261 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02048423 0,03822993 ! lactation GO:0007595 30 15 0,000 0,02048423 0,03820074 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02048423 0,0381716 ! reproductive cellular process GO:0048610 22 15 0,000 0,02048423 0,03814251 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02048423 0,03811346 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02048423 0,03808445 ! superoxide anion generation GO:0042554 22 15 0,000 0,02048423 0,03805549 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02048423 0,03802658 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02048423 0,0379977 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02048423 0,03796887 ! copper ion transport GO:0006825 22 15 0,000 0,02048423 0,03794009 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02048423 0,03791134 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02048423 0,03788264 ! sulfate transport GO:0008272 27 15 0,000 0,02048423 0,03785399 ! response to cAMP GO:0051591 25 15 0,000 0,02048423 0,03782538 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02048423 0,03779681 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02048423 0,03776828 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02048423 0,0377398 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02048423 0,03771136 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02048423 0,03768296 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02048423 0,03765461 ! vesicle coating GO:0006901 38 15 0,000 0,02048423 0,0376263 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02048423 0,03759803 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02048423 0,0375698 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02048423 0,03754162 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02048423 0,03751347 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02048423 0,03748537 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02048423 0,03745732 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02048423 0,0374293 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02048423 0,03740133 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02048423 0,03737339 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02048423 0,0373455 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02048423 0,03731765 ! histone deacetylation GO:0016575 24 15 0,000 0,02048423 0,03728985 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02048423 0,03726208 ! water homeostasis GO:0030104 28 15 0,000 0,02048423 0,03723435 ! cofactor transport GO:0051181 30 15 0,000 0,02048423 0,03720667 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02048423 0,03717903 ! muscle maintenance GO:0046716 26 15 0,000 0,02048423 0,03715143 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02048423 0,03712387 ! intestinal absorption GO:0050892 31 15 0,000 0,02048423 0,03709635 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02048423 0,03706887 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02048423 0,03704143 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02048423 0,03701403 ! cell killing GO:0001906 32 15 0,000 0,02048423 0,03698668 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02048423 0,03695936 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02048423 0,03693208 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02048423 0,03690485 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02048423 0,03687765 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02048423 0,0368505 ! actin filament polymerization GO:0030041 27 15 0,000 0,02048423 0,03682338 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02048423 0,0367963 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02183513 0,03919415 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02183513 0,03916537 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02183513 0,03913663 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02183513 0,03910794 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02183513 0,03907929 ! bone remodeling GO:0046849 28 16 0,000 0,02183513 0,03905068 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02183513 0,03902212 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02183513 0,03899359 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02183513 0,03896511 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02183513 0,03893667 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02183513 0,03890827 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02183513 0,03887991 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02183513 0,03885159 ! startle response GO:0001964 28 16 0,000 0,02183513 0,03882331 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02183513 0,03879508 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02183513 0,03876688 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02183513 0,03873873 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02183513 0,03871062 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02183513 0,03868255 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02183513 0,03865452 ! pituitary gland development GO:0021983 30 16 0,000 0,02183513 0,03862653 ! response to osmotic stress GO:0006970 27 16 0,000 0,02183513 0,03859858 ! lysosomal transport GO:0007041 31 16 0,000 0,02183513 0,03857067 ! L-amino acid transport GO:0015807 33 16 0,000 0,02183513 0,0385428 ! stem cell development GO:0048864 46 16 0,000 0,02183513 0,03851497 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02183513 0,03848718 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,02183513 0,03845943 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02183513 0,03843172 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02183513 0,03840405 ! axon cargo transport GO:0008088 46 16 0,000 0,02183513 0,03837643 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02183513 0,03834884 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02183513 0,03832129 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02183513 0,03829378 ! DNA replication initiation GO:0006270 28 16 0,000 0,02183513 0,03826631 ! neuron recognition GO:0008038 40 16 0,000 0,02183513 0,03823888 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02183513 0,03821148 ! tissue regeneration GO:0042246 27 16 0,000 0,02183513 0,03818413 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02183513 0,03815682 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02183513 0,03812954 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02183513 0,03810231 ! biomineral formation GO:0031214 22 16 0,000 0,02183513 0,03807511 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02183513 0,03804795 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02183513 0,03802084 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02183513 0,03799375 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02183513 0,03796671 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02183513 0,03793971 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02183513 0,03791274 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02183513 0,03788582 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02183513 0,03785893 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02183513 0,03783208 ! peptide hormone processing GO:0016486 27 16 0,000 0,02183513 0,03780527 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02318421 0,04011263 ! metencephalon development GO:0022037 32 17 0,000 0,02318421 0,04008424 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02318421 0,04005589 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02318421 0,04002758 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02318421 0,03999932 ! signal complex assembly GO:0007172 47 17 0,000 0,02318421 0,03997109 ! filopodium assembly GO:0046847 42 17 0,000 0,02318421 0,0399429 ! endothelial cell migration GO:0043542 31 17 0,000 0,02318421 0,03991475 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02318421 0,03988664 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02318421 0,03985857 ! glial cell development GO:0021782 28 17 0,000 0,02318421 0,03983054 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02318421 0,03980255 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02318421 0,0397746 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02318421 0,03974669 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02318421 0,03971882 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02318421 0,03969098 ! myoblast differentiation GO:0045445 50 17 0,000 0,02318421 0,03966319 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02318421 0,03963543 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02318421 0,03960771 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02318421 0,03958004 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02318421 0,0395524 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02318421 0,0395248 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02318421 0,03949723 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02318421 0,03946971 ! NAD metabolic process GO:0019674 33 17 0,000 0,02318421 0,03944222 ! membrane budding GO:0006900 42 17 0,000 0,02318421 0,03941478 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02318421 0,03938737 ! regulation of protein binding GO:0043393 33 17 0,000 0,02318421 0,03935999 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02318421 0,03933266 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02318421 0,03930537 ! genitalia development GO:0048806 32 17 0,000 0,02318421 0,03927811 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02318421 0,03925089 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02318421 0,03922371 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02318421 0,03919656 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02318421 0,03916945 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02318421 0,03914239 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02318421 0,03911535 ! steroid catabolic process GO:0006706 34 17 0,000 0,02318421 0,03908836 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02318421 0,0390614 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02318421 0,03903448 ! gas transport GO:0015669 26 17 0,000 0,02318421 0,0390076 ! organic cation transport GO:0015695 32 17 0,000 0,02318421 0,03898075 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02318421 0,03895394 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02318421 0,03892717 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02318421 0,03890043 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02453147 0,04113272 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02453147 0,04110451 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02453147 0,04107634 ! limbic system development GO:0021761 40 18 0,000 0,02453147 0,0410482 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02453147 0,04102011 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02453147 0,04099205 ! adult walking behavior GO:0007628 36 18 0,000 0,02453147 0,04096403 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02453147 0,04093605 ! heart looping GO:0001947 34 18 0,000 0,02453147 0,04090811 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02453147 0,0408802 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02453147 0,04085234 ! centrosome cycle GO:0007098 26 18 0,000 0,02453147 0,04082451 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02453147 0,04079672 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02453147 0,04076897 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02453147 0,04074125 ! glycine metabolic process GO:0006544 30 18 0,000 0,02453147 0,04071357 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02453147 0,04068593 ! response to retinoic acid GO:0032526 31 18 0,000 0,02453147 0,04065833 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02453147 0,04063077 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02453147 0,04060324 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02453147 0,04057575 ! DNA integration GO:0015074 32 18 0,000 0,02453147 0,04054829 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02453147 0,04052088 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02453147 0,0404935 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02453147 0,04046616 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02453147 0,04043885 ! neural crest cell migration GO:0001755 41 18 0,000 0,02453147 0,04041158 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02453147 0,04038435 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02453147 0,04035716 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02453147 0,04033 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02453147 0,04030288 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02453147 0,04027579 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02453147 0,04024874 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02453147 0,04022173 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02453147 0,04019475 ! detection of bacterium GO:0016045 22 18 0,000 0,02453147 0,04016781 ! nerve development GO:0021675 34 18 0,000 0,02453147 0,04014091 ! defense response to virus GO:0051607 43 18 0,000 0,02453147 0,04011404 ! microspike assembly GO:0030035 46 18 0,000 0,02453147 0,04008721 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02453147 0,04006041 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0258769 0,04222931 ! positive regulation of translation GO:0045727 31 19 0,000 0,0258769 0,04220112 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0258769 0,04217297 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0258769 0,04214485 ! neuron maturation GO:0042551 46 19 0,000 0,0258769 0,04211677 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0258769 0,04208873 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,0258769 0,04206073 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0258769 0,04203277 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0258769 0,04200484 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0258769 0,04197694 ! inositol metabolic process GO:0006020 33 19 0,000 0,0258769 0,04194909 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0258769 0,04192127 ! memory GO:0007613 34 19 0,000 0,0258769 0,04189349 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0258769 0,04186575 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0258769 0,04183804 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0258769 0,04181037 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0258769 0,04178274 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0258769 0,04175514 ! cerebral cortex development GO:0021987 40 19 0,000 0,0258769 0,04172758 ! pigmentation during development GO:0048066 42 19 0,000 0,0258769 0,04170005 ! response to vitamin A GO:0033189 32 19 0,000 0,0258769 0,04167256 ! heme metabolic process GO:0042168 40 19 0,000 0,0258769 0,04164511 ! neuromuscular junction development GO:0007528 43 19 0,000 0,0258769 0,0416177 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0258769 0,04159032 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,0258769 0,04156297 ! response to fungus GO:0009620 26 19 0,000 0,0258769 0,04153566 ! peptide cross-linking GO:0018149 39 19 0,000 0,0258769 0,04150839 ! protein export from nucleus GO:0006611 40 19 0,000 0,0258769 0,04148115 ! heart process GO:0003015 32 19 0,000 0,0258769 0,04145395 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0258769 0,04142679 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0258769 0,04139966 ! visual learning GO:0008542 38 19 0,000 0,0258769 0,04137256 ! cellular pigmentation GO:0033059 37 19 0,000 0,0258769 0,04134551 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0258769 0,04131848 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0258769 0,0412915 ! vitamin transport GO:0051180 31 19 0,000 0,0258769 0,04126454 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0258769 0,04123762 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0258769 0,04121074 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0258769 0,0411839 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0258769 0,04115708 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0258769 0,04113031 ! cilium assembly GO:0042384 38 19 0,000 0,0258769 0,04110356 ! peptide hormone secretion GO:0030072 32 19 0,000 0,0258769 0,04107685 ! protein secretion GO:0009306 45 20 0,000 0,02722052 0,04318165 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02722052 0,04315363 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02722052 0,04312564 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02722052 0,04309769 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02722052 0,04306978 ! skin development GO:0043588 42 20 0,000 0,02722052 0,0430419 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02722052 0,04301406 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02722052 0,04298626 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02722052 0,04295849 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02722052 0,04293075 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,02722052 0,04290306 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02722052 0,0428754 ! response to vitamin GO:0033273 36 20 0,000 0,02722052 0,04284777 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02722052 0,04282018 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02722052 0,04279262 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02722052 0,0427651 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02722052 0,04273762 ! response to alkaloid GO:0043279 38 20 0,000 0,02722052 0,04271017 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02722052 0,04268276 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02722052 0,04265538 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02722052 0,04262804 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02722052 0,04260073 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02722052 0,04257346 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02722052 0,04254622 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02722052 0,04251901 ! body fluid secretion GO:0007589 33 20 0,000 0,02722052 0,04249185 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02722052 0,04246471 ! peptide secretion GO:0002790 38 20 0,000 0,02722052 0,04243761 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02722052 0,04241055 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02722052 0,04238352 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02722052 0,04235652 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02722052 0,04232956 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02722052 0,04230263 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02722052 0,04227574 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02722052 0,04224888 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02722052 0,04222206 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02722052 0,04219527 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02722052 0,04216851 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02722052 0,04214179 ! regulation of glucose import GO:0046324 30 20 0,000 0,02722052 0,0421151 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02722052 0,04208844 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02722052 0,04206182 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02722052 0,04203523 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02722052 0,04200868 ! regulation of cell killing GO:0031341 46 21 0,000 0,02856233 0,04405162 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02856233 0,04402382 ! hormone secretion GO:0046879 39 21 0,000 0,02856233 0,04399607 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02856233 0,04396834 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02856233 0,04394066 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02856233 0,043913 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02856233 0,04388538 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02856233 0,0438578 ! ovarian follicle development GO:0001541 39 21 0,000 0,02856233 0,04383025 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02856233 0,04380274 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02856233 0,04377526 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02856233 0,04374781 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02856233 0,0437204 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02856233 0,04369303 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02856233 0,04366568 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02856233 0,04363837 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02856233 0,0436111 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02856233 0,04358386 ! sensory perception of pain GO:0019233 33 21 0,000 0,02856233 0,04355666 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02856233 0,04352948 ! diencephalon development GO:0021536 36 21 0,000 0,02856233 0,04350235 ! collagen fibril organization GO:0030199 62 21 0,000 0,02856233 0,04347524 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02856233 0,04344817 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02856233 0,04342113 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02856233 0,04339413 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02856233 0,04336716 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02856233 0,04334022 ! collagen catabolic process GO:0030574 29 21 0,000 0,02856233 0,04331332 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02856233 0,04328645 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02856233 0,04325962 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02856233 0,04323281 ! actin filament-based movement GO:0030048 47 21 0,000 0,02856233 0,04320604 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02856233 0,04317931 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02990232 0,04517709 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02990232 0,04514917 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02990232 0,04512128 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02990232 0,04509343 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02990232 0,04506561 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02990232 0,04503783 ! microtubule-based transport GO:0010970 59 22 0,000 0,02990232 0,04501008 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02990232 0,04498236 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02990232 0,04495468 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02990232 0,04492703 ! cellular response to starvation GO:0009267 37 22 0,000 0,02990232 0,04489942 ! vacuolar transport GO:0007034 41 22 0,000 0,02990232 0,04487184 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02990232 0,04484429 ! fucose metabolic process GO:0006004 44 22 0,000 0,02990232 0,04481678 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02990232 0,0447893 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02990232 0,04476186 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02990232 0,04473445 ! ureteric bud development GO:0001657 50 22 0,000 0,02990232 0,04470707 ! cell aging GO:0007569 48 22 0,000 0,02990232 0,04467973 ! stem cell differentiation GO:0048863 57 22 0,000 0,02990232 0,04465242 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02990232 0,04462514 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02990232 0,0445979 ! cytolysis GO:0019835 27 22 0,000 0,02990232 0,04457069 ! renal system process GO:0003014 42 22 0,000 0,02990232 0,04454351 ! vasodilation GO:0042311 40 22 0,000 0,02990232 0,04451637 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02990232 0,04448925 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02990232 0,04446218 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02990232 0,04443513 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02990232 0,04440812 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02990232 0,04438114 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,02990232 0,04435419 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02990232 0,04432728 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,02990232 0,0443004 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02990232 0,04427355 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02990232 0,04424673 ! sarcomere organization GO:0045214 32 22 0,000 0,02990232 0,04421995 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,02990232 0,0441932 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02990232 0,04416648 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02990232 0,04413979 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02990232 0,04411314 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02990232 0,04408652 ! gut development GO:0048565 44 22 0,000 0,02990232 0,04405993 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02990232 0,04403337 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,02990232 0,04400684 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02990232 0,04398035 ! protein stabilization GO:0050821 41 22 0,000 0,02990232 0,04395388 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,03124049 0,04589328 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03124049 0,0458657 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03124049 0,04583815 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03124049 0,04581064 ! gluconeogenesis GO:0006094 38 23 0,000 0,03124049 0,04578316 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03124049 0,04575571 ! viral genome replication GO:0019079 44 23 0,000 0,03124049 0,0457283 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03124049 0,04570091 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03124049 0,04567356 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03124049 0,04564625 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03124049 0,04561896 ! regeneration GO:0031099 42 23 0,000 0,03124049 0,04559171 ! axis specification GO:0009798 43 23 0,000 0,03124049 0,04556449 ! visual behavior GO:0007632 46 23 0,000 0,03124049 0,04553731 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03124049 0,04551015 ! response to ethanol GO:0045471 47 23 0,000 0,03124049 0,04548303 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03124049 0,04545594 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03124049 0,04542888 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03124049 0,04540186 ! peroxisome organization GO:0007031 43 23 0,000 0,03124049 0,04537487 ! lysosome organization GO:0007040 47 23 0,000 0,03124049 0,04534791 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03124049 0,04532098 ! vesicle targeting GO:0006903 49 23 0,000 0,03124049 0,04529408 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03124049 0,04526722 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03124049 0,04524038 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03124049 0,04521358 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03124049 0,04518681 ! DNA modification GO:0006304 36 23 0,000 0,03124049 0,04516007 ! fatty acid transport GO:0015908 47 23 0,000 0,03124049 0,04513337 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03124049 0,04510669 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03124049 0,04508005 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03124049 0,04505344 ! hormone transport GO:0009914 41 23 0,000 0,03124049 0,04502686 ! cell-cell recognition GO:0009988 28 23 0,000 0,03124049 0,04500031 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03124049 0,04497379 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03124049 0,04494731 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03124049 0,04492085 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03257686 0,04681487 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03257686 0,04678735 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03257686 0,04675986 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03257686 0,0467324 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03257686 0,04670498 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03257686 0,04667758 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03257686 0,04665022 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03257686 0,04662289 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03257686 0,0465956 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03257686 0,04656833 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03257686 0,0465411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03257686 0,0465139 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03257686 0,04648673 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03257686 0,04645959 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03257686 0,04643249 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03257686 0,04640541 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03257686 0,04637837 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03257686 0,04635136 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03257686 0,04632438 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03257686 0,04629743 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03257686 0,04627051 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03257686 0,04624363 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03257686 0,04621677 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03257686 0,04618995 ! membrane depolarization GO:0051899 45 24 0,000 0,03257686 0,04616316 ! pallium development GO:0021543 56 24 0,000 0,03257686 0,04613639 ! oogenesis GO:0048477 44 24 0,000 0,03257686 0,04610966 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03257686 0,04608296 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03257686 0,0460563 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03257686 0,04602966 ! platelet activation GO:0030168 41 24 0,000 0,03257686 0,04600305 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03257686 0,04597648 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03257686 0,04594993 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03257686 0,04592342 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03257686 0,04589693 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03257686 0,04587048 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03257686 0,04584406 ! regulation of amine transport GO:0051952 41 24 0,000 0,03257686 0,04581766 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03391143 0,04766722 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03391143 0,0476398 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03391143 0,04761243 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03391143 0,04758508 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03391143 0,04755776 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03391143 0,04753048 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03391143 0,04750322 ! phototransduction GO:0007602 37 25 0,000 0,03391143 0,047476 ! keratinization GO:0031424 37 25 0,000 0,03391143 0,04744881 ! vasculogenesis GO:0001570 49 25 0,000 0,03391143 0,04742165 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03391143 0,04739452 ! vacuole organization GO:0007033 49 25 0,000 0,03391143 0,04736742 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03391143 0,04734035 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03391143 0,04731332 ! receptor metabolic process GO:0043112 53 25 0,000 0,03391143 0,04728631 ! chromosome condensation GO:0030261 48 25 0,000 0,03391143 0,04725934 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03391143 0,04723239 ! regulation of behavior GO:0050795 48 25 0,000 0,03391143 0,04720548 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03391143 0,0471786 ! interaction with host GO:0051701 66 25 0,000 0,03391143 0,04715175 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03391143 0,04712493 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03391143 0,04709814 ! immunoglobulin production GO:0002377 62 25 0,000 0,03391143 0,04707138 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03391143 0,04704465 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03391143 0,04701795 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03391143 0,04699128 ! liver development GO:0001889 55 25 0,000 0,03391143 0,04696464 ! protein tetramerization GO:0051262 57 25 0,000 0,03391143 0,04693803 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03524419 0,04875513 ! myelination GO:0042552 50 26 0,000 0,03524419 0,04872754 ! initiation of viral infection GO:0019059 60 26 0,000 0,03524419 0,04869998 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03524419 0,04867245 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03524419 0,04864495 ! molting cycle process GO:0022404 52 26 0,000 0,03524419 0,04861748 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03524419 0,04859004 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03524419 0,04856264 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,03524419 0,04853526 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03524419 0,04850792 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03524419 0,04848061 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03524419 0,04845332 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03524419 0,04842607 ! digestive system process GO:0022600 49 26 0,000 0,03524419 0,04839885 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03524419 0,04837166 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03524419 0,0483445 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03524419 0,04831737 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03524419 0,04829027 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03524419 0,0482632 ! neural crest cell development GO:0014032 59 26 0,000 0,03524419 0,04823617 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03524419 0,04820916 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03524419 0,04818218 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03524419 0,04815523 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03524419 0,04812832 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03524419 0,04810143 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03524419 0,04807457 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03524419 0,04804774 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03524419 0,04802095 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03524419 0,04799418 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03524419 0,04796744 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03524419 0,04794073 ! blastocyst development GO:0001824 50 26 0,000 0,03524419 0,04791405 ! telomere organization GO:0032200 46 26 0,000 0,03524419 0,04788741 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03524419 0,04786079 ! neural tube closure GO:0001843 58 26 0,000 0,03524419 0,0478342 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03524419 0,04780764 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03524419 0,04778111 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03657515 0,04955801 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03657515 0,04953054 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03657515 0,0495031 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03657515 0,04947569 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03657515 0,04944831 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03657515 0,04942096 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03657515 0,04939364 ! iron ion transport GO:0006826 65 27 0,000 0,03657515 0,04936635 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03657515 0,04933909 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03657515 0,04931186 ! tube lumen formation GO:0035148 59 27 0,000 0,03657515 0,04928466 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03657515 0,04925749 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03657515 0,04923035 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03657515 0,04920324 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03657515 0,04917616 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03657515 0,04914912 ! response to starvation GO:0042594 47 27 0,000 0,03657515 0,0491221 ! response to toxin GO:0009636 49 27 0,000 0,03657515 0,04909511 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03657515 0,04906814 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03657515 0,04904121 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03657515 0,04901431 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03657515 0,04898744 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03657515 0,0489606 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03657515 0,04893378 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,03790431 0,05068431 ! neuron fate commitment GO:0048663 52 28 0,000 0,03790431 0,05065658 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03790431 0,05062889 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03790431 0,05060122 ! protein amino acid acylation GO:0043543 59 28 0,000 0,03790431 0,05057358 ! vesicle docking GO:0048278 55 28 0,000 0,03790431 0,05054598 ! circadian rhythm GO:0007623 56 28 0,000 0,03790431 0,0505184 ! dendrite development GO:0016358 67 28 0,000 0,03790431 0,05049086 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03790431 0,05046334 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03790431 0,05043586 ! base-excision repair GO:0006284 41 28 0,000 0,03790431 0,0504084 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03790431 0,05038097 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03790431 0,05035358 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03790431 0,05032621 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03790431 0,05029888 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03790431 0,05027157 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03790431 0,05024429 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03790431 0,05021705 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03790431 0,05018983 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03790431 0,05016264 ! lipid oxidation GO:0034440 48 28 0,000 0,03790431 0,05013548 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03790431 0,05010835 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03790431 0,05008125 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03923168 0,05180702 ! translational initiation GO:0006413 66 29 0,000 0,03923168 0,05177903 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03923168 0,05175107 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03923168 0,05172314 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03923168 0,05169524 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03923168 0,05166738 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03923168 0,05163954 ! primary neural tube formation GO:0014020 61 29 0,000 0,03923168 0,05161173 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03923168 0,05158395 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03923168 0,0515562 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03923168 0,05152849 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03923168 0,0515008 ! somitogenesis GO:0001756 52 29 0,000 0,03923168 0,05147314 ! synaptogenesis GO:0007416 46 29 0,000 0,03923168 0,05144551 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03923168 0,05141791 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03923168 0,05139034 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03923168 0,0513628 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03923168 0,05133529 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,04055725 0,05304141 ! phenol metabolic process GO:0018958 56 30 0,000 0,04055725 0,05301303 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,04055725 0,05298468 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,04055725 0,05295636 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,04055725 0,05292807 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,04055725 0,05289982 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,04055725 0,05287159 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,04055725 0,05284339 ! acute-phase response GO:0006953 50 30 0,000 0,04055725 0,05281522 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,04055725 0,05278708 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,04055725 0,05275897 ! myofibril assembly GO:0030239 50 30 0,000 0,04055725 0,0527309 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,04055725 0,05270285 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,04055725 0,05267483 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,04055725 0,05264684 ! cell fate determination GO:0001709 64 30 0,000 0,04055725 0,05261888 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,04055725 0,05259095 ! phospholipid transport GO:0015914 65 30 0,000 0,04055725 0,05256305 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,04055725 0,05253518 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,04055725 0,05250734 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,04055725 0,05247953 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,04055725 0,05245175 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,04055725 0,052424 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,04055725 0,05239627 ! regulation of coagulation GO:0050818 52 30 0,000 0,04055725 0,05236858 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04188103 0,05404931 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04188103 0,05402077 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04188103 0,05399227 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04188103 0,05396379 ! cell junction assembly GO:0034329 85 31 0,000 0,04188103 0,05393534 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04188103 0,05390693 ! ovulation cycle process GO:0022602 55 31 0,000 0,04188103 0,05387854 ! peptide transport GO:0015833 60 31 0,000 0,04188103 0,05385018 ! male gonad development GO:0008584 56 31 0,000 0,04188103 0,05382185 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04188103 0,05379356 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04188103 0,05376529 ! detection of light stimulus GO:0009583 44 31 0,000 0,04188103 0,05373705 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,04188103 0,05370884 ! natural killer cell activation GO:0030101 50 31 0,000 0,04188103 0,05368066 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04188103 0,05365252 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04188103 0,0536244 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04188103 0,05359631 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04188103 0,05356824 ! eye morphogenesis GO:0048592 65 31 0,000 0,04188103 0,05354021 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04188103 0,05351221 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04320302 0,05517249 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04320302 0,05514366 ! collagen metabolic process GO:0032963 49 32 0,000 0,04320302 0,05511487 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04320302 0,0550861 ! spindle organization GO:0007051 50 32 0,000 0,04320302 0,05505736 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04320302 0,05502866 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04320302 0,05499998 ! metanephros development GO:0001656 81 32 0,000 0,04320302 0,05497134 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04320302 0,05494272 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,04320302 0,05491414 ! muscle cell development GO:0055001 52 32 0,000 0,04320302 0,05488558 ! mesoderm formation GO:0001707 73 32 0,000 0,04320302 0,05485705 ! ovulation cycle GO:0042698 57 32 0,000 0,04320302 0,05482855 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04320302 0,05480009 ! BMP signaling pathway GO:0030509 71 32 0,000 0,04320302 0,05477165 ! hindbrain development GO:0030902 65 32 0,000 0,04320302 0,05474324 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04320302 0,05471486 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04320302 0,05468651 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,04320302 0,05465819 ! gene silencing GO:0016458 71 32 0,000 0,04320302 0,0546299 ! regulation of pH GO:0006885 56 33 0,000 0,04452322 0,05627016 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04452322 0,05624107 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04452322 0,056212 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04452322 0,05618297 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04452322 0,05615396 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04452322 0,05612499 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04452322 0,05609604 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04452322 0,05606713 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04452322 0,05603824 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04452322 0,05600938 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04452322 0,05598056 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04452322 0,05595176 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04452322 0,05592299 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04452322 0,05589426 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04452322 0,05586555 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04584164 0,05749031 ! glial cell differentiation GO:0010001 67 34 0,000 0,04584164 0,05746081 ! post-embryonic development GO:0009791 76 34 0,000 0,04584164 0,05743134 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04584164 0,05740191 ! cholesterol transport GO:0030301 62 34 0,000 0,04584164 0,0573725 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04584164 0,05734312 ! spliceosome assembly GO:0000245 75 34 0,000 0,04584164 0,05731378 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04584164 0,05728446 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04584164 0,05725517 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04584164 0,05722592 ! cell fate specification GO:0001708 56 34 0,000 0,04584164 0,05719669 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04584164 0,05716749 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04584164 0,05713833 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04584164 0,05710919 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04715827 0,0587195 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04715827 0,05868959 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04715827 0,05865971 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04715827 0,05862985 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04715827 0,05860003 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04715827 0,05857024 ! membrane docking GO:0022406 69 35 0,000 0,04715827 0,05854048 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04715827 0,05851075 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04715827 0,05848105 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04715827 0,05845138 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04715827 0,05842174 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04715827 0,05839213 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04715827 0,05836254 ! telencephalon development GO:0021537 81 35 0,000 0,04715827 0,05833299 ! sterol transport GO:0015918 63 35 0,000 0,04715827 0,05830347 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04715827 0,05827398 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04715827 0,05824452 ! placenta development GO:0001890 53 35 0,000 0,04715827 0,05821509 ! vesicle localization GO:0051648 70 35 0,000 0,04715827 0,05818569 ! regulation of muscle development GO:0048634 82 36 0,000 0,04847313 0,05977782 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04847313 0,05974766 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04847313 0,05971753 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04847313 0,05968743 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04847313 0,05965736 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04847313 0,05962732 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04847313 0,05959731 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04847313 0,05956733 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04847313 0,05953738 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04847313 0,05950747 ! aerobic respiration GO:0009060 56 36 0,000 0,04847313 0,05947758 ! cytokine production GO:0001816 68 36 0,000 0,04847313 0,05944772 ! embryonic organ development GO:0048568 67 36 0,000 0,04847313 0,05941789 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04847313 0,05938809 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,04978621 0,06096627 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04978621 0,06093573 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04978621 0,06090521 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04978621 0,06087473 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04978621 0,06084428 ! odontogenesis GO:0042476 74 37 0,000 0,04978621 0,06081386 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04978621 0,06078346 ! cell junction organization GO:0034330 96 37 0,000 0,04978621 0,0607531 ! tissue remodeling GO:0048771 78 37 0,000 0,04978621 0,06072277 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04978621 0,06069247 ! female gonad development GO:0008585 71 37 0,000 0,04978621 0,0606622 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04978621 0,06063196 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,04978621 0,06060175 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04978621 0,06057157 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,05109751 0,062136 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05109751 0,06210509 ! meiosis I GO:0007127 74 38 0,000 0,05109751 0,06207421 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05109751 0,06204335 ! organic anion transport GO:0015711 82 38 0,000 0,05109751 0,06201253 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05109751 0,06198174 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05109751 0,06195098 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,05109751 0,06192025 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05109751 0,06188955 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05109751 0,06185888 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05109751 0,06182825 ! regulation of protein stability GO:0031647 77 38 0,000 0,05109751 0,06179764 ! spermatid development GO:0007286 69 38 0,000 0,05109751 0,06176706 ! glycogen metabolic process GO:0005977 63 38 0,000 0,05109751 0,06173651 ! pigment metabolic process GO:0042440 87 38 0,000 0,05109751 0,06170599 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,05109751 0,06167551 ! neural tube formation GO:0001841 79 38 0,000 0,05109751 0,06164505 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05240705 0,06319369 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05240705 0,06316251 ! negative regulation of binding GO:0051100 71 39 0,000 0,05240705 0,06313137 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05240705 0,06310025 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05240705 0,06306917 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05240705 0,06303812 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05240705 0,06300709 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,05240705 0,0629761 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05240705 0,06294514 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,05240705 0,06291421 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05240705 0,06288331 ! glucan metabolic process GO:0044042 64 39 0,000 0,05240705 0,06285244 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05371481 0,06438924 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,05371481 0,06435766 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05371481 0,06432611 ! learning GO:0007612 82 40 0,000 0,05371481 0,0642946 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05371481 0,06426311 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05371481 0,06423166 ! lipid homeostasis GO:0055088 75 40 0,000 0,05371481 0,06420023 ! mismatch repair GO:0006298 58 40 0,000 0,05371481 0,06416884 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05371481 0,06413747 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05371481 0,06410614 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05371481 0,06407484 ! mRNA catabolic process GO:0006402 79 41 0,000 0,0550208 0,06560069 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,0550208 0,06556869 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,0550208 0,06553672 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,0550208 0,06550478 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,0550208 0,06547288 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,0550208 0,065441 ! gliogenesis GO:0042063 91 41 0,000 0,0550208 0,06540915 ! feeding behavior GO:0007631 69 41 0,000 0,0550208 0,06537734 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,0550208 0,06534556 ! mesenchymal cell development GO:0014031 94 41 0,000 0,0550208 0,06531381 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,0550208 0,06528208 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,0550208 0,06525039 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,0550208 0,06521874 ! spermatid differentiation GO:0048515 73 41 0,000 0,0550208 0,06518711 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,0550208 0,06515551 ! RNA modification GO:0009451 64 41 0,000 0,0550208 0,06512394 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05632503 0,06663537 ! ear morphogenesis GO:0042471 64 42 0,000 0,05632503 0,06660312 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05632503 0,0665709 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,05632503 0,0665387 ! T cell differentiation GO:0030217 93 42 0,000 0,05632503 0,06650654 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05632503 0,06647442 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05632503 0,06644232 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05632503 0,06641025 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05632503 0,06637822 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05632503 0,06634621 ! cytokinesis GO:0000910 84 42 0,000 0,05632503 0,06631424 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05632503 0,06628229 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05762749 0,06778236 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05762749 0,06774974 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05762749 0,06771715 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05762749 0,0676846 ! regulation of tube size GO:0035150 76 43 0,000 0,05762749 0,06765207 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05762749 0,06761958 ! glucose transport GO:0015758 66 43 0,000 0,05762749 0,06758711 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05762749 0,06755468 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05762749 0,06752228 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05762749 0,06748991 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05762749 0,06745758 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05762749 0,06742527 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05762749 0,06739299 ! segmentation GO:0035282 78 43 0,000 0,05762749 0,06736075 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05762749 0,06732853 ! neuron migration GO:0001764 85 43 0,000 0,05762749 0,06729635 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05762749 0,06726419 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05892819 0,06874956 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,05892819 0,06871674 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05892819 0,06868396 ! hexose transport GO:0008645 68 44 0,000 0,05892819 0,0686512 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05892819 0,06861848 ! striated muscle contraction GO:0006941 85 44 0,000 0,05892819 0,06858579 ! phagocytosis GO:0006909 105 44 0,000 0,05892819 0,06855313 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05892819 0,0685205 ! double-strand break repair GO:0006302 85 44 0,000 0,05892819 0,06848791 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,06022714 0,06996429 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,06022714 0,06993103 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,06022714 0,06989781 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,06022714 0,06986462 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,06022714 0,06983147 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,06022714 0,06979834 ! biopolymer methylation GO:0043414 91 45 0,000 0,06022714 0,06976524 ! B cell differentiation GO:0030183 124 45 0,000 0,06022714 0,06973218 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,06022714 0,06969915 ! female gamete generation GO:0007292 71 45 0,000 0,06022714 0,06966614 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,06022714 0,06963317 ! developmental growth GO:0048589 88 45 0,000 0,06022714 0,06960024 ! maintenance of location in cell GO:0051651 101 45 0,000 0,06022714 0,06956733 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06152433 0,0710321 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06152433 0,07099855 ! glycolysis GO:0006096 71 46 0,000 0,06152433 0,07096503 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,06152433 0,07093154 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,06152433 0,07089808 ! leukocyte migration GO:0050900 75 46 0,000 0,06152433 0,07086465 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06152433 0,07083126 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06152433 0,07079789 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06152433 0,07076456 ! pigmentation GO:0043473 103 46 0,000 0,06152433 0,07073126 ! cell growth GO:0016049 90 46 0,000 0,06152433 0,07069799 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,06152433 0,07066475 ! neural tube development GO:0021915 91 47 0,000 0,06281976 0,07211874 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,06281976 0,07208486 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06411344 0,07353481 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06411344 0,0735003 ! mitochondrial transport GO:0006839 94 48 0,000 0,06411344 0,07346582 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,06411344 0,07343138 ! cellular component disassembly GO:0022411 89 48 0,000 0,06411344 0,07339697 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,06411344 0,07336259 ! endosome transport GO:0016197 127 48 0,000 0,06411344 0,07332825 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,06411344 0,07329393 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06411344 0,07325965 ! male sex differentiation GO:0046661 93 48 0,000 0,06411344 0,0732254 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06411344 0,07319119 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06411344 0,073157 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06411344 0,07312285 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06411344 0,07308872 ! methylation GO:0032259 97 48 0,000 0,06411344 0,07305463 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06540537 0,07449199 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06540537 0,07445728 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06540537 0,0744226 ! JNK cascade GO:0007254 106 49 0,000 0,06540537 0,07438796 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,06540537 0,07435334 ! protein homooligomerization GO:0051260 84 49 0,000 0,06540537 0,07431876 ! regulation of action potential GO:0001508 102 50 0,000 0,06669556 0,07574954 ! regulation of ion transport GO:0043269 86 50 0,000 0,06669556 0,07571434 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06669556 0,07567917 ! endocrine system development GO:0035270 109 50 0,000 0,06669556 0,07564404 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06669556 0,07560893 ! activation of caspase activity GO:0006919 95 50 0,000 0,06669556 0,07557386 ! regulation of ossification GO:0030278 123 50 0,000 0,06669556 0,07553883 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06669556 0,07550382 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06669556 0,07546885 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06669556 0,07543391 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06669556 0,07539901 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06669556 0,07536413 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,067984 0,07678452 ! viral infectious cycle GO:0019058 104 51 0,000 0,067984 0,07674904 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,067984 0,07671359 ! peptide metabolic process GO:0006518 80 51 0,000 0,067984 0,07667817 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,067984 0,07664278 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,067984 0,07660743 ! positive regulation of binding GO:0051099 88 52 0,000 0,0692707 0,07802135 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,0692707 0,0779854 ! Notch signaling pathway GO:0007219 111 52 0,000 0,0692707 0,07794948 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,0692707 0,07791359 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,0692707 0,07787773 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,0692707 0,07784191 ! excretion GO:0007588 87 52 0,000 0,0692707 0,07780612 ! histone modification GO:0016570 104 52 0,000 0,0692707 0,07777037 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,0692707 0,07773464 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,0692707 0,07769895 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,0692707 0,07766329 ! amino acid activation GO:0043038 98 52 0,000 0,0692707 0,07762767 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,07055566 0,07903139 ! positive regulation of growth GO:0045927 96 53 0,000 0,07055566 0,07899517 ! inner ear development GO:0048839 89 53 0,000 0,07055566 0,07895899 ! chromatin remodeling GO:0006338 122 53 0,000 0,07055566 0,07892283 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,07055566 0,07888671 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,07055566 0,07885063 ! vesicle organization GO:0016050 127 53 0,000 0,07055566 0,07881457 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,07055566 0,07877855 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,07055566 0,07874256 ! cartilage development GO:0051216 99 53 0,000 0,07055566 0,07870661 ! synapse organization GO:0050808 102 53 0,000 0,07055566 0,07867068 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,07183888 0,08006495 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,07183888 0,08002844 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,07183888 0,07999197 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,07183888 0,07995552 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,07183888 0,07991912 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,07183888 0,07988274 ! membrane fusion GO:0006944 122 54 0,000 0,07183888 0,0798464 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,07183888 0,07981008 ! covalent chromatin modification GO:0016569 115 54 0,000 0,07183888 0,07977381 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,07183888 0,07973756 ! regulation of cell shape GO:0008360 142 54 0,000 0,07183888 0,07970135 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,07183888 0,07966517 ! RNA catabolic process GO:0006401 103 55 0,000 0,07312036 0,08104948 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,07312036 0,08101272 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07312036 0,08097599 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07312036 0,0809393 ! cell recognition GO:0008037 98 55 0,000 0,07312036 0,08090265 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07312036 0,08086602 ! cell maturation GO:0048469 107 55 0,000 0,07312036 0,08082943 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,07312036 0,08079287 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,07312036 0,08075635 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,07440011 0,08213262 ! glucose catabolic process GO:0006007 88 56 0,000 0,07440011 0,08209552 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07440011 0,08205845 ! regulation of DNA replication GO:0006275 105 56 0,000 0,07440011 0,08202142 ! RNA elongation GO:0006354 90 56 0,000 0,07440011 0,08198443 ! chloride transport GO:0006821 102 57 0,000 0,07567813 0,08335513 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,07567813 0,08331757 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07567813 0,08328004 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,07567813 0,08324254 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,07567813 0,08320508 ! heart morphogenesis GO:0003007 105 57 0,000 0,07567813 0,08316765 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07567813 0,08313025 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,07567813 0,08309289 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07695443 0,08445627 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,07695443 0,08441835 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,07695443 0,08438046 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,07695443 0,0843426 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07695443 0,08430478 ! gastrulation GO:0007369 122 58 0,000 0,07695443 0,08426699 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,07695443 0,08422924 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,07695443 0,08419152 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07695443 0,08415383 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,07695443 0,08411618 ! maintenance of location GO:0051235 124 58 0,000 0,07695443 0,08407856 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07822899 0,08543291 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,07950183 0,08678417 ! lipid modification GO:0030258 112 60 0,000 0,07950183 0,08674541 ! DNA catabolic process GO:0006308 94 60 0,000 0,07950183 0,08670669 ! regulation of endocytosis GO:0030100 104 60 0,000 0,07950183 0,086668 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,07950183 0,08662934 ! adult behavior GO:0030534 104 60 0,000 0,07950183 0,08659072 ! kidney development GO:0001822 133 60 0,000 0,07950183 0,08655213 ! positive regulation of secretion GO:0051047 110 61 0,000 0,08077295 0,0878968 ! regulation of cellular component size GO:0032535 125 61 0,000 0,08077295 0,08785767 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,08077295 0,08781857 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,08077295 0,0877795 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,08077295 0,08774047 ! regulation of heart contraction GO:0008016 123 61 0,000 0,08077295 0,08770148 ! camera-type eye development GO:0043010 126 61 0,000 0,08077295 0,08766252 ! proton transport GO:0015992 117 61 0,000 0,08077295 0,08762359 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,08077295 0,0875847 ! viral reproductive process GO:0022415 132 62 0,000 0,08204235 0,08892168 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,08204235 0,08888225 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,08204235 0,08884285 ! tRNA processing GO:0008033 102 62 0,000 0,08204235 0,08880349 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,08204235 0,08876416 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,08331004 0,0900958 ! regulation of mitosis GO:0007088 112 63 0,000 0,08331004 0,09005594 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,08331004 0,09001611 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08331004 0,08997631 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08331004 0,08993655 ! hydrogen transport GO:0006818 121 64 0,000 0,084576 0,09126289 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,084576 0,09122259 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,084576 0,09118234 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,084576 0,09114212 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08584026 0,09246374 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,08584026 0,09242298 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08584026 0,09238227 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08584026 0,09234159 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08584026 0,09230095 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,08584026 0,09226034 ! ear development GO:0043583 114 66 0,000 0,0871028 0,09357614 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,0871028 0,09353501 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,0871028 0,09349391 ! gonad development GO:0008406 115 66 0,000 0,0871028 0,09345285 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,0871028 0,09341183 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,08836364 0,09472241 ! activation of MAPK activity GO:0000187 124 67 0,000 0,08836364 0,09468087 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,08836364 0,09463936 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,08836364 0,09459788 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,08836364 0,09455645 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,08836364 0,09451505 ! secondary metabolic process GO:0019748 125 67 0,000 0,08836364 0,09447369 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,08836364 0,09443236 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,08962277 0,09573609 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08962277 0,09569424 ! hexose catabolic process GO:0019320 113 68 0,000 0,08962277 0,09565244 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08962277 0,09561067 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08962277 0,09556893 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08962277 0,09552724 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08962277 0,09548558 ! viral reproduction GO:0016032 142 68 0,000 0,08962277 0,09544395 ! regulation of lipase activity GO:0060191 137 68 0,000 0,08962277 0,09540237 ! adaptive immune response GO:0002250 126 68 0,000 0,08962277 0,09536081 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,08962277 0,0953193 ! negative regulation of cell size GO:0045792 144 69 0,000 0,0908802 0,09661459 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,0908802 0,09657256 ! lung development GO:0030324 165 69 0,000 0,0908802 0,09653058 ! urogenital system development GO:0001655 149 69 0,000 0,0908802 0,09648862 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,0908802 0,09644671 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,0908802 0,09640483 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,0908802 0,09636299 ! developmental maturation GO:0021700 128 69 0,000 0,0908802 0,09632118 ! single fertilization GO:0007338 83 69 0,000 0,0908802 0,09627941 ! cell redox homeostasis GO:0045454 114 70 0,000 0,09213592 0,09756743 ! germ cell development GO:0007281 133 70 0,000 0,09213592 0,09752516 ! activation of immune response GO:0002253 120 70 0,000 0,09213592 0,09748292 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,09213592 0,09744072 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,09338995 0,09872421 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,09338995 0,09868151 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,09338995 0,09863885 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,09338995 0,09859622 ! appendage morphogenesis GO:0035107 150 72 0,000 0,09464228 0,0998752 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,09464228 0,09983208 ! respiratory tube development GO:0030323 171 72 0,000 0,09464228 0,09978899 ! actin filament organization GO:0007015 167 72 0,000 0,09464228 0,09974594 ! B cell activation GO:0042113 179 72 0,000 0,09464228 0,09970293 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,09464228 0,09965995 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,09464228 0,09961701 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,09464228 0,09957411 ! appendage development GO:0048736 151 73 0,000 0,09589292 0,10084649 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,09589292 0,10080309 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09589292 0,10075974 ! regulation of immune effector process GO:0002697 156 73 0,000 0,09589292 0,10071642 ! acute inflammatory response GO:0002526 118 74 0,000 0,09714186 0,10198434 ! amino acid transport GO:0006865 148 74 0,000 0,09714186 0,10194053 ! regulation of caspase activity GO:0043281 136 74 0,000 0,09714186 0,10189676 ! respiratory system development GO:0060541 175 74 0,000 0,09714186 0,10185303 ! organelle localization GO:0051640 155 74 0,000 0,09714186 0,10180933 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,09838911 0,1030723 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,09838911 0,10302812 ! reproductive structure development GO:0048608 131 75 0,000 0,09838911 0,10298397 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,09838911 0,10293987 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,09838911 0,1028958 ! axon guidance GO:0007411 162 75 0,000 0,09838911 0,10285177 ! rhythmic process GO:0048511 142 75 0,000 0,09838911 0,10280778 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,09963468 0,10406478 ! learning or memory GO:0007611 161 76 0,000 0,09963468 0,1040203 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,09963468 0,10397587 ! regulation of blood pressure GO:0008217 134 76 0,000 0,09963468 0,10393147 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,09963468 0,10388712 ! amine catabolic process GO:0009310 136 77 0,000 0,10087855 0,10513921 ! neurotransmitter transport GO:0006836 142 77 0,000 0,10087855 0,10509437 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,10087855 0,10504958 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,10087855 0,10500482 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,10087855 0,1049601 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,10087855 0,10491541 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,10087855 0,10487077 ! regulation of catabolic process GO:0009894 173 77 0,000 0,10087855 0,10482616 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,10212075 0,10607185 ! antigen processing and presentation GO:0019882 117 78 0,000 0,10212075 0,10602677 ! fertilization GO:0009566 99 78 0,000 0,10212075 0,10598173 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,10212075 0,10593673 ! blood coagulation GO:0007596 151 79 0,000 0,10336126 0,10717809 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,10336126 0,10713261 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,10336126 0,10708718 ! protein oligomerization GO:0051259 149 79 0,000 0,10336126 0,10704178 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,10336126 0,10699643 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,1046001 0,10823297 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,1046001 0,10818715 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,1046001 0,10814136 ! meiosis GO:0007126 143 81 0,000 0,10583726 0,10937412 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,10583726 0,10932787 ! response to hypoxia GO:0001666 178 81 0,000 0,10583726 0,10928167 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,10583726 0,1092355 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,10707274 0,11046398 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,10707274 0,11041735 ! protein import into nucleus GO:0006606 174 82 0,000 0,10707274 0,11037076 ! meiotic cell cycle GO:0051321 144 82 0,000 0,10707274 0,11032421 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,10830655 0,11154845 ! exocytosis GO:0006887 153 83 0,000 0,10830655 0,11150144 ! response to drug GO:0042493 149 83 0,000 0,10830655 0,11145447 ! response to oxygen levels GO:0070482 183 83 0,000 0,10830655 0,11140754 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,10830655 0,11136065 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,10830655 0,1113138 ! nuclear import GO:0051170 177 83 0,000 0,10830655 0,11126699 ! inorganic anion transport GO:0015698 156 83 0,000 0,10830655 0,11122022 ! T cell activation GO:0042110 189 84 0,000 0,1095387 0,11243825 ! response to nutrient GO:0007584 135 84 0,000 0,1095387 0,11239103 ! digestion GO:0007586 130 84 0,000 0,1095387 0,11234384 ! hemostasis GO:0007599 165 85 0,000 0,11076917 0,11355815 ! negative regulation of transport GO:0051051 164 85 0,000 0,11076917 0,11351052 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,11076917 0,11346293 ! negative regulation of growth GO:0045926 168 85 0,000 0,11076917 0,11341537 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,11076917 0,11336786 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,11076917 0,11332039 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,11076917 0,11327295 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,11076917 0,11322556 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,11199798 0,11443374 ! regulation of lyase activity GO:0051339 169 86 0,000 0,11199798 0,11438589 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,11199798 0,11433809 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,11322512 0,1155426 ! mitochondrion organization GO:0007005 159 87 0,000 0,11322512 0,11549435 ! nucleosome assembly GO:0006334 126 87 0,000 0,11322512 0,11544615 ! regulation of protein transport GO:0051223 165 87 0,000 0,11322512 0,11539799 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 0,000 0,11445061 0,11659835 ! sensory perception of smell GO:0007608 117 88 0,000 0,11445061 0,11654974 ! chromatin assembly GO:0031497 128 88 0,000 0,11445061 0,11650118 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,11445061 0,11645266 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,11567443 0,11764889 ! regulation of DNA binding GO:0051101 167 89 0,000 0,11567443 0,11759993 ! tube morphogenesis GO:0035239 194 89 0,000 0,11567443 0,11755101 ! cellular defense response GO:0006968 123 89 0,000 0,11567443 0,11750214 ! protein localization in nucleus GO:0034504 192 89 0,000 0,11567443 0,1174533 ! regulation of neurological system process GO:0031644 175 89 0,000 0,11567443 0,1174045 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,1168966 0,11859568 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,1168966 0,11854645 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,11811711 0,11973448 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,11811711 0,11968482 ! gland development GO:0048732 220 91 0,000 0,11811711 0,1196352 ! defense response to bacterium GO:0042742 112 91 0,000 0,11811711 0,11958562 ! bone development GO:0060348 206 92 0,000 0,11933597 0,12076959 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,11933597 0,12071958 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,12055318 0,12190042 ! amine transport GO:0015837 181 93 0,000 0,12055318 0,12184999 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,12055318 0,1217996 ! vitamin metabolic process GO:0006766 153 93 0,000 0,12055318 0,12174925 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,12176874 0,12292605 ! female pregnancy GO:0007565 166 94 0,000 0,12176874 0,12287528 ! sterol metabolic process GO:0016125 166 94 0,000 0,12176874 0,12282454 ! regulation of membrane potential GO:0042391 179 94 0,000 0,12176874 0,12277385 ! regulation of defense response GO:0031347 171 95 0,000 0,12298266 0,12394663 ! nucleosome organization GO:0034728 143 95 0,000 0,12298266 0,12389552 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,12298266 0,12384445 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,12298266 0,12379342 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,12298266 0,12374244 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,12298266 0,12369149 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,12298266 0,12364059 ! sex differentiation GO:0007548 171 96 0,000 0,12419493 0,12480799 ! regulation of T cell activation GO:0050863 175 96 0,000 0,12419493 0,12475667 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,12540556 0,125921 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,12540556 0,12586927 ! transcription initiation GO:0006352 171 97 0,000 0,12540556 0,12581757 ! regulation of protein localization GO:0032880 188 97 0,000 0,12540556 0,12576593 ! leukocyte differentiation GO:0002521 232 98 0,000 0,12661456 0,12692629 ! forebrain development GO:0030900 210 98 0,000 0,12661456 0,12687422 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,12661456 0,12682221 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,12902763 0,12918627 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,12902763 0,12913335 ! positive regulation of immune response GO:0050778 175 100 0,000 0,12902763 0,12908047 ! hormone metabolic process GO:0042445 171 100 0,000 0,12902763 0,12902763